LOCUS       DAVLXH010000001        85947 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00028199
            SAMN33607166-rid17955573.denovo.001, whole genome shotgun sequence.
ACCESSION   DAVLXH010000001 DAVLXH010000000
VERSION     DAVLXH010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607166
            Sequence Read Archive: SRR23725544
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 85947)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 85947)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721421.1
            Genome Coverage       :: 115x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:42:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,210
            CDSs (total)                      :: 2,161
            Genes (coding)                    :: 2,023
            CDSs (with protein)               :: 2,023
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 73 of 138
            Pseudo Genes (incomplete)         :: 60 of 138
            Pseudo Genes (internal stop)      :: 40 of 138
            Pseudo Genes (multiple problems)  :: 31 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..85947
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607166-rid17955573.denovo.001"
                     /strain="AUSMDU00028199"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1349"
     gene            505..1368
                     /locus_tag="VYO11_000001"
     CDS             505..1368
                     /locus_tag="VYO11_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HEV1594637.1"
                     /translation="MIEKMELGEFYKELRLARKLKQSDVACAGLTASQLSKFELGQSM
                     LSADKLILAIQGINMNFDEFGHKLNNYQESPHMRIGRRVVDCFSHQDIAALEQLLEEV
                     DQEQMAQTYRRLNAIVIKNALHSLDKSYPLTEEDSEFLTTYLYAIESWTWFELYLFCN
                     TMPFLSNQDLIFLSTSLLEKSKEFKELVHNRWYMKSGYLNIISELMERKLFSYIPIFE
                     AELERMLRPYDVFEKVLWQFLKKMQIFLQTKGSNQKEIEHFIQSLQVLENPQLTALFE
                     LRLQQYKELID"
     gene            1654..1887
                     /locus_tag="VYO11_000002"
     CDS             1654..1887
                     /locus_tag="VYO11_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000933479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1594638.1"
                     /translation="MLNLQFAETMELTEAELQDVRGGNLVNSMGGGGRSGISGWGVPG
                     IYPGWGNQGMSPNRGAFDWTIDLADGLFGRRRR"
     gene            1909..2586
                     /locus_tag="VYO11_000003"
     CDS             1909..2586
                     /locus_tag="VYO11_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV1594639.1"
                     /translation="MKKMKEVKFHLATGLLILTYYLIFNVTSDLDFMVALSDNMYYVF
                     QVLLVLILGTIATIAFVKSEHWKECGRFQFRWSYLGVFLLSFFLLFVWANLTTYIFPR
                     TQNGSTVVEVATSLTGISYFVTRILYTSIIAPVSEEVVCRGLLMTSLSKVNRYYLDVL
                     VSAAIFGAMHVLQYGWITTDFIKYFGMGLIFCMMFRYTRSIYWAIALHASWNSFLLIV
                     TLLVFGY"
     gene            2598..3263
                     /locus_tag="VYO11_000004"
     CDS             2598..3263
                     /locus_tag="VYO11_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV1594640.1"
                     /translation="MKKIISHRYFIIVFLLVIADQKFSVLVLRSDLVAGLSDFAYYLS
                     DMMLNFLVVLFALIAMIWSGKWQKINSRKFKGSYLFYSFLALLAFVAWNFVTFFLFPP
                     TRNEISYQHAAPTFTGATAFLMYFFYPVIAGPIFEDMIYRGLVMTALEKGKKWGLDVL
                     GSAVLFGVSHISNHGWVLTDFVFYMGGGLIFAVLFRMTKSIYWPIGLHIVYNGIGQLL
                     MLL"
     gene            3335..4561
                     /locus_tag="VYO11_000005"
     CDS             3335..4561
                     /locus_tag="VYO11_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEV1594641.1"
                     /translation="MKVFLQNRDFRQLTINQWISTLGDTIFYLAFLNYVADASFAPLA
                     ILLITISETLPQVLQIFLGVLADFQHHRVLKYTVISFTKFLLYSIVSLSLSGQSFSLL
                     LVTFICLINLLSDTLSYFSGAMLTPIFIRIIGQDHLAEAIGFKQSTVSLVKTISNILG
                     GVLLGILSIQFISLLNALTFLIAFLGILFIKTDLLKVEKTISYQEGLSVKSFCQHLLQ
                     SSKLIWNMNKVLLVLFIISTSQAVINVTVPVSTLFLRNQPFLNLQTGQSLALLSTFEL
                     SALIVGSLVSGYLQHTISIKTALYASLVIQLLLLVGFATVRFDWILIFSTLDAFFAGV
                     LSPRLQELVFKQIPEESMGAVQSSISAITVVLPSLFTISLVTIATSFGTLAVSFVLLL
                     FLLVAFVMLLNIRESI"
     gene            complement(4957..5034)
                     /locus_tag="VYO11_000006"
                     /pseudo
     CDS             complement(4957..5034)
                     /locus_tag="VYO11_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            5105..5761
                     /locus_tag="VYO11_000007"
     CDS             5105..5761
                     /locus_tag="VYO11_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001141648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HEV1594642.1"
                     /translation="MPTALGYVSIGLACGTIGAPYVTPVEMGLMSLFVYAGSAQFAML
                     ALIVVQAPVAAIAMTVFLINLRLFLLSLHASTYFRHTSLWYNIGMSSILTDETYGVLM
                     GELAHTDKVNPMWMHGNNLNSYVAWFVGTVVGTDLGGLLPNPEIFGLDFALVGMFIGI
                     FASQFQMMQRRIPVRNLLIILAVVAVSFFLLLTVVSQSLAVLFATLLGCSMGVVLDGQ
                     "
     gene            5751..6074
                     /locus_tag="VYO11_000008"
     CDS             5751..6074
                     /locus_tag="VYO11_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000253911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HEV1594643.1"
                     /translation="MVSKYLLLAVIFSGLVTWILRMIPFILVKYKGLPAIVERFLKFL
                     PVSIIFALILSSVVTGKVGSLPQIKWLDFLAVFPTAWVAFRYRNLVGTVLFGVVLIAI
                     LRLVF"
     gene            6178..7008
                     /locus_tag="VYO11_000009"
     CDS             6178..7008
                     /locus_tag="VYO11_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV1594644.1"
                     /translation="MKKIVKYSSLAALGLVAAGVLAACSGGAKKEGEAASKKEIIVAT
                     NGSPRPFIYEENGELTGYEIEVVRAIFKDSDKYDVKFEKTEWSGVFAGLDADRYNMAV
                     NNLSYTKERAEKYLYAAPIAQNPNVLVVKKDDSSIKSLDDIGGKSTEVVQATTSAKQL
                     EAYNAEHTDNPTILNYTKADFQQIMVRLSDGQFDYKIFDKIGVETVIKNQGLDNLKVI
                     ELPSDQQPYVYPLLAQGQDELKSFVDKRIKELYKDGTLEKLSKQFFGDTYLPAEADIK
                     "
     gene            7162..8016
                     /locus_tag="VYO11_000010"
     CDS             7162..8016
                     /locus_tag="VYO11_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000694494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HEV1594645.1"
                     /translation="MKIKKWLGLAALATVAGLALAACGNSEKKADNATTIKIATVNRS
                     GSEEKRWDKIQELVKKDGITLEFTEFTDYSQPNKATADGEVDLNAFQHYNFLNNWNKE
                     NGKDLVAIADTYISPIRLYSGLNGSANKYTKVEDIPANGEIAVPNDATNESRALYLLQ
                     SAGLIKLDVSGTALATVANIKENPKNLKITELDASQTARSLSSVDAAVVNNTFVTEAK
                     LDYKKALFKEQADENSKQWYNIIVAKKDWETSPKADAIKKVIAAYHTDDVKKVIEESS
                     DGLDQPVW"
     gene            8116..9489
                     /locus_tag="VYO11_000011"
     CDS             8116..9489
                     /locus_tag="VYO11_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HEV1594646.1"
                     /translation="MVFPSEQEQIEKFEKDHVVQHYFEVLRTLISKKSVFAQQVGLKE
                     VANYLGEIFKRVGAEVEIDESYTAPFVMAHFKSSRPDAKTLIFYNHYDTVPADGDQVW
                     TEDPFTLSVRNGFMYGRGVDDDKGHITARLSALRKYMQHHDDLPVNISFIMEGAEESA
                     STDLDKYLEKHADKLRGADLLVWEQGTKNALEQLEISGGNKGIVTFDAKVKSADVDIH
                     SSYGGVVESAPWYLLQALQSLRAADGRILVEGLYEEVQELNEREMALLETYGQRNPEE
                     VSRIYGLELPLLQEERMAFLKRFFFEPALNIEGIQSGYQGQGVKTILPAEASAKLEVR
                     LVPGLEPHDVLEKIRKQLDKNGFDKVELYYTLGEMSYRSDMSAPAILNVIELAKKFYP
                     QGVSVLPTTAGTGPMHTVFDALEVPMVAFGLGNANSRDHGGDENVRIADYYTHIELVE
                     ELIRSYE"
     gene            9482..10543
                     /locus_tag="VYO11_000012"
     CDS             9482..10543
                     /locus_tag="VYO11_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000085652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HEV1594647.1"
                     /translation="MSRDIIKLDQIDVTFHQKKRTITAVKDVTIHIQEGDIYGIVGYS
                     GAGKSTLVRVINLLQKPSAGKITIDDDVIFDGKVTLTAEQLRRKRQDIGMIFQHFNLM
                     SQKTAEENVAFALKHSGLSKEEKKAKVAKLLDLVGLADRAENYPSQLSGGQKQRVAIA
                     RALANDPKILISDESTSALDPKTTKQILALLQDLNQKLGLTVVLITHEMQIVKDIANR
                     VAVMQDGHLIEEGSVLEIFSNPKQPLTQDFISTATGIDEAMVKIEKQEIVEHLSENSL
                     LVQLKYAGASTDEPLLNELYKHYQVMANILYGNIEILDGTPVGELVVVLSGEKAALAG
                     AQEAIRQAGVQLKVLKGVQ"
     gene            10545..11237
                     /locus_tag="VYO11_000013"
     CDS             10545..11237
                     /locus_tag="VYO11_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1594648.1"
                     /translation="MESLIQTYLPNVYKMGWAGQAGWGTAIYLTLYMTVLSFIIGGFL
                     GLVAGLFLVLTAPGGVLENKVVFWILDKITSIFRAVPFIILLAILSPLSHLIVKTSIG
                     PNAALVPLSFAVFAFFARQVQVVLAELDGGVIEAAQASGATFWDIVGVYLSEGLPDLI
                     RVTTVTLISLVGETAMAGAVGAGGIGNVAIAYGFNRYNHDVTILATIIIILIIFAIQF
                     LGDFSTKKLSHK"
     gene            complement(11267..11836)
                     /locus_tag="VYO11_000014"
     CDS             complement(11267..11836)
                     /locus_tag="VYO11_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HEV1594649.1"
                     /translation="MKKSILTTLLFAVLYFLCMGIGVLLGNLFDQTGNMFYAPAFTAL
                     VGGSVYMILVAKVPRFGAITTIGLVIAFFFLGTKHGAGSFLPGIICGLLADEVAHLGK
                     YKDKTKNFLSFIIFAFSTTGPILLMWIAPKAYMATLLARGKSQEYIDRIMVAPNPGTV
                     LLFIASIVIGALVGALIGQALSKKFAQKI"
     gene            11971..12585
                     /locus_tag="VYO11_000015"
     CDS             11971..12585
                     /locus_tag="VYO11_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000532354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HEV1594650.1"
                     /translation="MGRFLDFVFNRFFLGMIATAFFWLLTLAGGIILGLAPASATLMS
                     LYAEHGYSFREYSLKEAWSLYKQNFVSSNLIFYSFLGVGLVLTYGLYLLVQLPHQTIV
                     HLIATLLNVLVVALIFLAYTVSLKLQVYFALSYRNSLKLSLIGIFMSLAAVAKVLLGT
                     VLLVAIGYYMPALLFFVGIGMWHFFISDMLEPVYEIIHEKLATK"
     gene            12587..14233
                     /locus_tag="VYO11_000016"
     CDS             12587..14233
                     /locus_tag="VYO11_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV1594651.1"
                     /translation="MKQFWLHTLLRTYSSVMIIIIASFAILLSYADWDSREKEAQRVA
                     QRVTARTVSEIEYYHRESTQIAQALVENQARIEGIYKYFSLSMPDYFYWQLERKASPY
                     ISVSLYENVDDLYVRNDFVTGVAIAFQDYKEVYVSTKDKRSGEKIRAEDFKPAGNSFA
                     IPVSDPVSDQDLGVIYISLDSAVLYHAIDNTRGHTPMAVTVTSPFDTEIFHIGETVDK
                     ESENWLVGLTSHGYQVQVAVPKNFVLQGTVTSSALIVGLSLLFIVILYLTLRQTFANY
                     QKQVVDLVESIQVIAQGEEGRRIDISEKDQELLLIAETTNDMLDRLEKNIHDIYQLEL
                     SQKDANMRALQAQINPHFMYNTLEFLRMYAVMQSQDELADIIYEFSSLLRNNISDERE
                     TLLKQELEFCRKYSYLCMVRYPKSIAYGFKIDPELENMKIPKFTLQPLVENYFAHGVD
                     HRRTDNVISIKALKQDGFVEILVVDNGRGMSAEKLANIREKLSQRYFEHQASYSDQRQ
                     SIGIVNVHERFVLYFGDRYAITIESAEQAGVQYRITIQDE"
     gene            14245..15531
                     /locus_tag="VYO11_000017"
     CDS             14245..15531
                     /locus_tag="VYO11_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1594652.1"
                     /translation="MYKVLLVDDEYMVTEGLKRLIPFDKWDMEVVATASHADEALEYV
                     QENPVDVIISDVNMPDKTGLDMIREMKEILPDAAYILLSGYQEFDYVKRAMNLSVVDY
                     LVKPVDKVELGNLLEKIAGQLGERGKKSQTLSQELDEAGFVSYLGDKENWWIGLSKEK
                     QGSFTIPYYVLGQDWQIFISGHPLDGLVVTPFEAPYQEHFERWKLNAEKTLFYGSVNL
                     QQSESLFAYYEPIYRVIIQGNLNQIVEELNLLEKVVLENTPRVSITKQLFIQFVMDVF
                     HLFEHLKADDMTDIVKTIHAIQSFDELVSYIKETLISFFGQYRMNENVVSVLEVIGRD
                     YQKELSLKDISKALFINPVYLGQLIKRETDSTFAELLNKQRIKAAQQLLLSTSDSIED
                     ICYAVGYSNLGYFYKVFRKLCGKSPKAYRKQVETIL"
     gene            15583..16116
                     /locus_tag="VYO11_000018"
     CDS             15583..16116
                     /locus_tag="VYO11_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1594653.1"
                     /translation="MKKKPIYLWVLLILSALISVPSLFGIVSPLPSKEALRAAQKQVA
                     GVNAQQLEDQLNYTYRVAEASHSIFNVALIVLSTILVVVAIVFLVRKNLQYANYTYVG
                     YVLLAIIGSIYGYVGLQDAVQLVQDESMRLTVSIGSKAVSIFYIVINVLFLALVFYKM
                     WRQQKALAEEEETEELA"
     gene            16194..16664
                     /gene="nrdI"
                     /locus_tag="VYO11_000019"
     CDS             16194..16664
                     /gene="nrdI"
                     /locus_tag="VYO11_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HEV1594654.1"
                     /translation="MKTISLVYISLSGNTESFVTRLKDYLLSQYKGIEVQKIHIKDLV
                     KEGKNFYEMDHPYVAFLPTYLEGGNGVDNGDVEILTTPVGDFIAYGNNASKCFGVVGS
                     GNRNFNNQYCLTAKQYSQRFGFPVLADFEMRGMLEDIKHVAAIIADLYELEKEN"
     gene            complement(16957..18219)
                     /locus_tag="VYO11_000020"
     CDS             complement(16957..18219)
                     /locus_tag="VYO11_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000075801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divalent metal cation transporter"
                     /protein_id="HEV1594655.1"
                     /translation="MSQAISLNQSTWASKLKAMGPGILMATAAVGGSHIVSSTQAGGS
                     YGWSLLLLVILANVFKYPFFRFGAEYTADTGKTLVEGYAEKGKLYLWIFFILNVFSAM
                     VNTAGVAILCSAIIASAFPMIGLSITQWSLILVAIIWAMLLFGGYKLLDGMVKWIMSA
                     LTIATVLAVIIAAVKHPEYSSDFVEKTPWQMAALPFIVSLLGWMPAPIEISAINSLWS
                     AEKRKTVNFNTEDALFDFNTGYIGTAILAVFFVALGALIQYPTGQAVEAASAKYISQF
                     VGMYASVLGEWSRYLITFIAFLCIFGTVITVIDGYSRVNQESLRLLISQKEDNRKSLN
                     IWMTITAIIGIVIIKFFAGQVSTMLRFAMIGSFLTTPFFALLNYALVTRENKNLPSWL
                     KHLAIAGLIFLFGFAIFFIYALAIGKAG"
     gene            complement(18529..18987)
                     /locus_tag="VYO11_000021"
     CDS             complement(18529..18987)
                     /locus_tag="VYO11_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3021 domain-containing protein"
                     /protein_id="HEV1594656.1"
                     /translation="MKKQVFHDAAAGVLIGLILSILFSLIYAPNTYAPLNPYSLIGQV
                     MDQQQVHGALVLLYCTLIWAAIGMLFNFGNRLFSRDWSMLRATLTHFFLMLAGFVPLA
                     TLAGWFPFHWIFYLQLIIEFAIVYLIIWAILYKREAKKVDHINQLLEHRK"
     gene            complement(18984..19424)
                     /locus_tag="VYO11_000022"
     CDS             complement(18984..19424)
                     /locus_tag="VYO11_000022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000861967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1594657.1"
                     /translation="MKVELQISETYEEEKLIVQAPQETEKVQKVIEFAENLDQREKIK
                     GKIYDQVYLVEIGKIQRFYIENRKVLAETASQTYSIDLRLYQVLKLLPTNFIQISQSE
                     IINIDSISHLKLTPNGLVEIFLKNESFTYSSRRYLKTIKEKLEL"
     gene            19780..21729
                     /gene="mutL"
                     /locus_tag="VYO11_000023"
     CDS             19780..21729
                     /gene="mutL"
                     /locus_tag="VYO11_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HEV1594658.1"
                     /translation="MSHIIELPEMLANQIAAGEVIERPASVVKELVENAIDAGSSQII
                     IEIEEAGLKKVQITDNGHGIAHDEVELALRRHATSKIKNQADLFRIRTLGFRGEALPS
                     IASVSVLTLLTAVDGASHGTKLVARGGEVEEVIPATSPVGTKVCVEDLFFNTPARLKY
                     MKSQQAELSHIIDIVNRLGLAHPEISFSLISDGKEMTRTAGTGQLRQAIAGIYGLVSA
                     KKMIEIENSDLDFEISGFVSLPELTRANRNYISLFINGRYIKNFLLNRAILDGFGSKL
                     MVGRFPLAVIHIHIDPYLADVNVHPTKQEVRISKEKELMTLVSEAIANSLKEQTLIPD
                     ALENLAKSTVRNREKVEQTILPLKENTLYYEKTEPSRPSQTEVADYQVELTDEGQDLT
                     LFAKETLDRLTKPAKLHFAERKPANYDQLDHPELDLASIDKAYDKLEREEASSFPELE
                     FFGQMHGTYLFAQGRDGLYIIDQHAAQERVKYEEYRESIGNVDQSQQQLLVPYIFEFP
                     ADDALRLKERMPLLEEVGVFLAEYGENQFILREHPIWMAEEEIESGIYEMCDMLLLTK
                     EVSIKKYRAELAIMMSCKRSIKANHRIDDHSARQLLYQLSQCDNPYNCPHGRPVLVHF
                     TKSDMEKMFRRIQENHTSLRELGKY"
     gene            complement(22054..22521)
                     /locus_tag="VYO11_000024"
     CDS             complement(22054..22521)
                     /locus_tag="VYO11_000024"
                     /EC_number="2.5.1.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6,7-dimethyl-8-ribityllumazine synthase"
                     /protein_id="HEV1594659.1"
                     /translation="MNTYEGNLVANNIKIGIVVARFNEFITSKLLSGALDNLKRENVN
                     EKDIEVAWVPGAFEIPLIASKMAKSKKYDAIICLGAVIRGNTSHYDYVCSEVSKGIAQ
                     ISLNSEIPVMFGVLTTDTIEQAIERAGTKAGNKGSECAQGAIEMVNLIRTLDA"
     gene            complement(22522..23727)
                     /locus_tag="VYO11_000025"
     CDS             complement(22522..23727)
                     /locus_tag="VYO11_000025"
                     /EC_number="3.5.4.25"
                     /EC_number="4.1.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP
                     cyclohydrolase II"
                     /protein_id="HEV1594660.1"
                     /translation="MEYRKIQEALEALQKGRLVLVIDDKDRENEGDLICSAQAATTEN
                     VNFMATYAKGLICMPMSESLANQLMLSPMVENNTDNHKTAFTVSIDYKETTTGISAEE
                     RGLTARMCVAEDITPSDFRRPGHMFPLIAKKGGVLERNGHTEATVDLLKLAGLKECGL
                     CCEIMNHDGKMMRTDDLIQFSKKHNIPLITIKELQEYRKVYDQLVERVSTVNMPTRYG
                     NFKAISYIDKLNGEHHLALIMGNIEDEANVLCRVHSECLTGDVLGSLRCDCGQQFDKA
                     MKMIVENGSGVLLYLRQEGRGIGLINKLKAYHLQDQGMDTLDANLALGFEGDLREYHI
                     GAQMLKDLGLQSLHLLTNNPDKVEQLEKYGITISSRISIEIEANPYDSFYLETKKNRM
                     GHILNMEEK"
     gene            complement(23747..24382)
                     /gene="ribE"
                     /locus_tag="VYO11_000026"
     CDS             complement(23747..24382)
                     /gene="ribE"
                     /locus_tag="VYO11_000026"
                     /EC_number="2.5.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin synthase"
                     /protein_id="HEV1594661.1"
                     /translation="MFTGIIEEIGKVERIQKDSRNCKLSIKASKILTDIHLGDSIAVN
                     GICLTVTHFNHQSFTVDVMNETWSRTALTLLKHGSEVNLERALSVNGRLGGHVVTGHI
                     DGTGKISSIKKDDNAVWYQINTQKEILDLIVEKGSITIDGISLTVAKVSKVNFSVSVI
                     PHTLEQTILKSKQVGSTVNLENDILGKYVQKLMDNSPKSEISKELLYQNGF"
     gene            complement(24367..25467)
                     /gene="ribD"
                     /locus_tag="VYO11_000027"
     CDS             complement(24367..25467)
                     /gene="ribD"
                     /locus_tag="VYO11_000027"
                     /EC_number="1.1.1.193"
                     /EC_number="3.5.4.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     diaminohydroxyphosphoribosylaminopyrimidine
                     deaminase/5-amino-6-(5-phosphoribosylamino)uracil
                     reductase RibD"
                     /protein_id="HEV1594662.1"
                     /translation="MSDSKYMKLAIKLAQKGAGYVNPNPMVGAVIVKDNHIIGQGYHE
                     FFGGPHAERNALKNCRESPVGATLYVTLEPCCHFGKTPPCIDAIIDSGITRVVIGSLD
                     CNPIVSGKGVKILEENNLQVTVGILENECLNLIKSFRKYITQHVPYVFMKYAMSMDGK
                     IATKTNQSKWITEEEARKHVHQLRHHVSAIMVGVNTVIQDDPLLTCRLEEGKNPIRII
                     CDTHLRTPLTSKIVKTANDIKTYIATSSEDKNKMKLYQNHGCEILSIKKKGNHIDLSS
                     LMQHLGNMQIDSLVLEGGSLMNWSALEQQIVDELKIYIAPKIFGGSAKFPVGGEGISL
                     PNDAIRLKPYAFSQIGNDYLIESEVIYPCSQE"
     regulatory      complement(25601..25715)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            25872..26465
                     /gene="ruvA"
                     /locus_tag="VYO11_000028"
     CDS             25872..26465
                     /gene="ruvA"
                     /locus_tag="VYO11_000028"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000271492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HEV1594663.1"
                     /translation="MYAYLKGIITKITAKYIVLETNGIGYILHVANPYAYSGQVNQEA
                     QIYVHQVVREDAHLLYGFRSEDEKKLFLSLISVSGIGPVSALAIIAADDNAGLVQAIE
                     TKNITYLTKFPKIGKKTAQQMVLDLEGKVVVAGDGLPAKVAVQASAENQELEEAMEAM
                     LALGYKATELKKIKKFFEGTTDTAENYIKSALKMLVK"
     gene            26475..27038
                     /locus_tag="VYO11_000029"
     CDS             26475..27038
                     /locus_tag="VYO11_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HEV1594664.1"
                     /translation="MTKRCSWVKMTNPLYIAYHDEEWAQPLHDDQALFELLCMETYQA
                     GLSWETVLNKRQAFREAFHSYQIHSVAEMTDTELEAMLENPAIIRNRAKIFATRANAQ
                     AFLQLQAEYGSFDAYLWSFVEGKTVVNDVPDYRQAPAKTPLSEKLAKDLKKRGFKFTG
                     PVAVLSFLQAAGLVDDHENDCEWKGLK"
     gene            27035..27712
                     /locus_tag="VYO11_000030"
     CDS             27035..27712
                     /locus_tag="VYO11_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000987430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV1594665.1"
                     /translation="MMSNKNKGILIFAILYTVLFVFDGVKLLASLMPSAIANYLVYVV
                     LALYGSFLFKDRLIQQWKEIRKTKRKFFFGVLTGWLFLILMTVVFEFVSEMLKQFVGL
                     DGQGLNQSNIQSTFQEQPLLIAVFACVIGPLVEELFFRQVLLHYLQERLPGLLSIILV
                     GLVFALTHMHSLALSEWIGAVGYLGGGLAFSIIYVKEKENIYYPLLVHMLSNSLSLII
                     LAISIVK"
     gene            complement(27849..28880)
                     /locus_tag="VYO11_000031"
     CDS             complement(27849..28880)
                     /locus_tag="VYO11_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000255096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HEV1594666.1"
                     /translation="MVSTIGIVSLSSGIIGEDFVKHEVDLGIQRLKDLGLNPIFLPHS
                     LKGLDFIKDHPEARAEDLIHAFSDDSIDMILCAIGRDDTYRLLPYLFENDQLQKVIKQ
                     KIFLGFSDTTMNHLMLHKLGIKTFYGQSFLADICELDKEMLAYSLHYFKELIETGRIS
                     EIRPSDVWYEERTDFSPTALGTPRVSHTNTGFDLLQGSAQFEGKILGGCLESLYDIFD
                     NSRYADSTELCQKYKLFPDLSDWEGKILLLETSEEKPKPEDFKKMLLTLKDTGIFAVI
                     NGLLVGKPMDETFHDDYKEALLDIIDSNIPIVYNLNVGHATPRAIVPFGVHAHVDAQE
                     QVILFDYNK"
     gene            complement(29135..29818)
                     /locus_tag="VYO11_000032"
     CDS             complement(29135..29818)
                     /locus_tag="VYO11_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HEV1594667.1"
                     /translation="MSQIDLQKLTKKNQEFVHIATQQFIKDGKTDAEIQTIFEEVIPQ
                     ILEEQSKGTTARSLYGAPTHWAHSFTVKEQYEKEHPKENDDPKLMIMDSALFITSLFA
                     LVSALTTFFAADQAFGYGLITLLLVGLVGGFAFYLMYYFVYQYYGPDMDRSQRPPFWK
                     SVLVILASMFLWLLVFFATSFLPASLNPVLDPLPLAIIGVALLALRFYLKKRLNIRSA
                     SAGPTRYQE"
     gene            complement(29830..30774)
                     /locus_tag="VYO11_000033"
     CDS             complement(29830..30774)
                     /locus_tag="VYO11_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000815632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HEV1594668.1"
                     /translation="MKQVFLSTTTEFKEIDTLEPGTWINLVNPTQNESLEIANTFDID
                     IADLRAPLDAEEMSRITIEDEYTLIIVDVPVTEERNNRTYYVTIPLGIIITEETIITT
                     CLEPLPVLDVFINRRLRNFYTFMRSRFIFQILYRNAELYLTALRSIDRKSEQIESQLH
                     QSTRNEELIELMELEKTIVYFKASLKTNERVIKKLTSSTSNIKKYLEDEDLLEDTLIE
                     TQQAIEMADIYGNVLHSMTETFASIISNNQNNIMKTLALVTIVMSIPTMVFSAYGMNF
                     KDNEIPLNGEPNAFWLIVFIAFAMSVSLTLYLIHKKWF"
     gene            complement(30935..32101)
                     /locus_tag="VYO11_000034"
     CDS             complement(30935..32101)
                     /locus_tag="VYO11_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000704663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEV1594669.1"
                     /translation="MKITEVIKKDGSKVYRANVYLGVDQVTGKKVKTKVTGRTQKEVK
                     QKANQEKIAFQKAGSTRQKAVTIKNYQELATLWLESYKNTVKPNTQGNVKKLIDNHIL
                     PIFGAYKLDKLTTPLIQSIINELADKTNRGEKAAFLHYDKIHALNKRILQYGVTMQAI
                     PSNPARDVVLPRNTQKAKRKKVKHFENQELKKFLGYLDNLDTHRYRYYYETTLYKFLL
                     ATGCRINEALALSWSDIDLDNAVVHITKTLNRDIEINSPKSKASYRDIDIDQATVSML
                     KQYKLRQTKEAWKIGQRERVVFSDFIHEYPSSSRLKRRLQTHFKRADVPNIGFHGFRH
                     THASLLLNSGIPYKELQYRLGHSTLSMTMDIYSHLSKENAKKAVSFYETALKAL"
     gene            complement(32186..33700)
                     /locus_tag="VYO11_000035"
     CDS             complement(32186..33700)
                     /locus_tag="VYO11_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001233766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA binding domain-containing protein"
                     /protein_id="HEV1594670.1"
                     /translation="MRKYDIPKLLLSGENQGVEFKEAKNSFPKDGMKTICSFANTNNG
                     LLILGVSENTKNKDFYISGVNDPDKVLDELYSLLNNPNKINRNVINEESVEVVNIKGK
                     EIVIIPVNKVDYKDKPIYLNDNIASTYFRQGTGDFRCSQEQINSMLRDSAKESFDSTL
                     IQDFSILDLDTETIKLYREKFDNINAEHPFSKLDNEQFLIKINALRRDRKDDKIKPTV
                     AGLLIFGTHNSIKEFIPHYNVEYVLKEFSENNRFKDRVIYDGTWGEDNLFNFFYLVIE
                     KLYLTLNDNSNIQENSMNRIGISKLRIAIREAFINSLIHSDYKSEKGIMIIRYPDRYI
                     FTNGGTLRIDIKDFFSGAHSDPRNYLIQEIFRFLNLCEKAGTGIPKIMEAVKESHLKY
                     PNLRTELDSVEFTLWDTSLIDNLDIDNEYEKKILELIIEHRFVTREALEEKLKIHKNT
                     ILKYLKKLVEKQAIDKFKSGRQYVYFITQNQDPEFQKYNHINAMYSLLEEIKRK"
     gene            complement(33861..34574)
                     /locus_tag="VYO11_000036"
     CDS             complement(33861..34574)
                     /locus_tag="VYO11_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001107589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV1594671.1"
                     /translation="MAKNSPQDLKNREYFSNNLNRVMKEKGIRQIDLHNALEIPKSTI
                     TGYVKGRSMPTSGNLQKLADYLGVKKSDLDPRFSDKDVYKEFLYMLDKQLDEEKYLVK
                     NVSKDKIFQKVKEREKRDKEIIELAKSKNFPISPEEFLTTITESLNEYNPKDNYEVLN
                     ALALKTSNILFWLDIVFQKTSSEFYIVFEDKEFNQEYYNKLYKKFENLFEEIKSLALQ
                     EAKKDKENLDDFALLWGID"
     gene            34727..34956
                     /locus_tag="VYO11_000037"
                     /pseudo
     CDS             34727..34956
                     /locus_tag="VYO11_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000438800.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            34972..35598
                     /locus_tag="VYO11_000038"
     CDS             34972..35598
                     /locus_tag="VYO11_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rha family transcriptional regulator"
                     /protein_id="HEV1594672.1"
                     /translation="MELVYMDGKKEPYTLSSIVAECAEVKHRHLKILLNKHREDFESF
                     GKVQFKISPSESGQNVRDYILNEQQATLLITYLRNTEPVKEFKKNLVKAFFEMREELS
                     KFRMQRALEKPKRKTLHDSIETWEAKPKHAHSTMNNLLLKAVTDMNAKQLREERGGYN
                     GIDSLTSDELEQYQAFEDMVIAMIGLNMSYQEIKAMAFRNKKTRQRSA"
     gene            35970..36422
                     /locus_tag="VYO11_000039"
     CDS             35970..36422
                     /locus_tag="VYO11_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000141097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1594673.1"
                     /translation="MTETTYENLTRHIDRISAEMREIGEKNGLSRLSLLANQTKFIKE
                     NLHRLLWIELPELNDSHKIEAVSKSTTGMFFHAGIFEMDAMRQAFFKRQAMHFFDNEA
                     EQQAYIEHAEKEYLEATITLKDILFNSKNGTQRVNKSCLIEKFEEAMQ"
     gene            36419..36619
                     /locus_tag="VYO11_000040"
     CDS             36419..36619
                     /locus_tag="VYO11_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000174331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1594674.1"
                     /translation="MTLNLDNMTQAEFDEVMAEIKEKRPNLFQFIADFVDRKVSTEEV
                     DEYLKMKHEKQVEFIKNYQARA"
     gene            36621..36836
                     /locus_tag="VYO11_000041"
     CDS             36621..36836
                     /locus_tag="VYO11_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1594675.1"
                     /translation="MNELDLTNTQSVIFMVVLIGLLLYLNHRDRKKSAQFERENQQRI
                     ETPSEDLSPDYGRYIQLAGVRVYGGTE"
     gene            36833..37174
                     /locus_tag="VYO11_000042"
     CDS             36833..37174
                     /locus_tag="VYO11_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEV1594676.1"
                     /translation="MSLSENDKRVLRLIKVGAENSITGAEISLITKLAERTVQDIISR
                     LITRHSVPIVGVRHGTFRGYFIPANKEELLDGAKAFYNQVQEEQKRLTVLLNADLESY
                     KETLKEVGGYV"
     gene            37167..37448
                     /locus_tag="VYO11_000043"
     CDS             37167..37448
                     /locus_tag="VYO11_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000492137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HEV1594677.1"
                     /translation="MFSLSRESEQDLAHGILEVVERYLEARDTVKPRLTGLISAQEVM
                     DELDIKYMTLQKWEKAGLRRYQPPLEDTRKIYYKISDIWKFLGVENGKV"
     gene            37583..38449
                     /locus_tag="VYO11_000044"
     CDS             37583..38449
                     /locus_tag="VYO11_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000158206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primase alpha helix C-terminal domain-containing
                     protein"
                     /protein_id="HEV1594678.1"
                     /translation="MTIYEAKGFQSNLVYPFDKIEPFQYIERFKPLVVPEGADIEEYK
                     RTQAPYCISGKVTPEKHGSYKRNNSSLIYRDLIFLDYDDIQGTSEGFIKAISSALFGY
                     SYILYPTIKHSLEKPRFRLVVKPDNVMNEATYKQVVKEIADKIGLPFDMASLTWSQLQ
                     GLPVTTGDPASYQKIVEHGLDYPVPQTTAEPVKQNAASLPYTPRPSGQKSMTMRIIDT
                     LFNGFGDEGGRNVALTRFVGLLFNKWVDCDLETAYELTKIANSVTVEPLPIEELDRTF
                     SSIARAEYRKRG"
     gene            38502..39971
                     /locus_tag="VYO11_000045"
     CDS             38502..39971
                     /locus_tag="VYO11_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase family protein"
                     /protein_id="HEV1594679.1"
                     /translation="MEQEHPPRTMKELENRIFKAGEEWRAEHTETKVNENTGDVTEKV
                     AMPQTFTVAKILSEIVTFTFISKSNIPDYSLLYIYDLDEGIYTASNDLFNLLCKTFDV
                     RIKPREWPQIKLMVRTLAKIRKPLESANLIPVQNGIINLETKELLPFSPKYVITSKIS
                     TAYHAPKRVPTDREGKTFDDWLNSIACNDSELVTLFWQIILEAINPNHTRNKFAIFYG
                     DGNNGKGTFQRFLINLIGESNISALKPAQFAEKHNLETLVGKVCNIGDEAPNEYLKNP
                     SDLMSITSGDTVLVNPKGRPAFEATFKLFNIFSGNYIPNGGNKTKGWYRRIMIVPFNA
                     DFNGEKEKPWIKNEFLANKEVLEYALYKAINQEPFTHFIEPKAVKGLLEEYQEDNDYL
                     LSWVKHEYMEKGWHELDVVPVFIVTRSLKHYAEDMGIPKPNVYGAGKETIKHLQQLTP
                     NRYSLRKKRVSPEDFEKLEAWDVDKIKMRTPQHSITKQE"
     gene            40334..40501
                     /locus_tag="VYO11_000046"
     CDS             40334..40501
                     /locus_tag="VYO11_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000865230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1594680.1"
                     /translation="MKVKLFEYTRRWEKEDFEKEIDDFMATVEVLDVKFSGTPSSESF
                     NSVAIVLVLYR"
     gene            40585..41115
                     /locus_tag="VYO11_000047"
     CDS             40585..41115
                     /locus_tag="VYO11_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1594681.1"
                     /translation="MTLKTFSSKAKTFTFTYEFKDLDTALVAGHALLGYMTGTYCQPV
                     ISLTYKDKGTLVAEYVEDHKLNKTFKRICDSFKDYHKQPGEAEAFEERYKRERVLQLK
                     ESEDFESLLNKVTDYELELLDYADRLLSDKPIPMDSMTAFATLEMLGDESISLLQKLD
                     VEGEYKGLAGYTEHLK"
     gene            41186..41695
                     /locus_tag="VYO11_000048"
     CDS             41186..41695
                     /locus_tag="VYO11_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000811078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1594682.1"
                     /translation="MKQLAIEAITKPMKLRGISKGIAELDGQRLEIDLDSLMIDFGGE
                     SFELDRIAGTKGGNRYFFLCPDCGRRCRLLYKRYLYFSCGTCLDIHKHTLNRSKTDCQ
                     YYWELALKEARKVEPGWSPRRGGYMFDSFPERPKYMKQKRYYKHYQKFINYTRKGDSF
                     WLNGLSSLR"
     gene            42902..43321
                     /locus_tag="VYO11_000049"
     CDS             42902..43321
                     /locus_tag="VYO11_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1492 domain-containing protein"
                     /protein_id="HEV1594683.1"
                     /translation="MTPEQVKEKLEGVKWINKEIKGLYLELETLEGGIIKKPTLSHSR
                     VQTSRENKTENNLISVLKLKEDTLQRIERLTEERMKISELIDKLANPLERSVLRLFYL
                     NDLVVSEVAEEIDRSNTTVYIIRQKAIEHLTGIVNGD"
     gene            43810..46641
                     /gene="uvrA"
                     /locus_tag="VYO11_000050"
     CDS             43810..46641
                     /gene="uvrA"
                     /locus_tag="VYO11_000050"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HEV1594684.1"
                     /translation="MQDKIVIHGARAHNLKNIDVEIPRDKLVVVTGLSGSGKSSLAFD
                     TLYAEGQRRYVESLSAYARQFLGNMEKPDVDAIDGLSPAISIDQKTTSKNPRSTVGTT
                     TEINDYLRLLYARVGTPYCINGHGAINASSVEQIVDKVLELPERQRLQILAPVIRKKK
                     GQHKSVIEKVQKDGYVRVRVDGEVYDVTEVPELSKSKQHNIDVVVDRIVIKEGIRSRL
                     FDSIEAALRIAEGYVIIDTMDDSELLFSEHYACPVCGFTVPELEPRLFSFNAPFGSCS
                     ECDGLGIKLEVDTDLVVPDASKTLHEGALAPWNPISSNYYPNMLEQAMKVFGVAMDKP
                     FEDLSEEDKNLILYGSDGKEFHFHYENEFGGVRDIDIPFEGVINNIKRRYHETNSDYT
                     RTQMRLYMNELTCGTCQGYRLNDQALSVRVGGQQGPHIGEISDLSIADHLDLVSQLTL
                     SENEAIIARPILKEIKDRLTFLNNVGLNYLTLSRSAGTLSGGESQRIRLATQIGSNLS
                     GVLYILDEPSIGLHQRDNDRLIASLKKMRDLGNTLIVVEHDEDTMREADYLIDVGPGA
                     GVFGGEIVAAGTPKQVARNSKSITGQYLSGKRVIPVPEERRVGNGRFIEVIGARENNL
                     QNVTARFPLGKFIAVTGVSGSGKSTLINSILKKAIAQKLNRNSDKPGKFKTITGIEHV
                     DRLIDIDQSPIGRTPRSNPATYTGVFDDIRDLFAQTNEAKIRGYKKGRFSFNVKGGRC
                     EACSGDGIIKIEMHFLPDVYVACEVCHGTRYNSETLEVHYKEKNISQVLDMTVNDAVE
                     FFQHIPKIQRKLQTIKDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSTGKSFYIL
                     DEPTTGLHTEDIARLLKVLARFVDDGNTVLVIEHNLDVIKTADHIIDLGPEGGVGGGT
                     IIVTGTPEEVAANEASYTGHYLKGKLHHE"
     gene            46634..47695
                     /locus_tag="VYO11_000051"
     CDS             46634..47695
                     /locus_tag="VYO11_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HEV1594685.1"
                     /translation="MNKRVQAFLAKMQEKELDGIIINNLKNVYYLTGFWGSNGTVFIS
                     RDRQVLVTDSRYIIAAKQETSGFEIVADRDELAVIAGIVKDMGLTRIGFEDEISVSYY
                     HRMQAAFAGLNLLPQTQFVEGLRMIKDEAEIAAIRKACSISDQAFRDALDFIKPGKTE
                     IEIANFLDFRMRELGASGLSFDTILASGINSSKPHAHPMHKPVELGEAITMDFGCLYD
                     HYVSDMTRTIYLGHVSDEQAEIYNTVLKANQALIDQAKAGLGFRDFDKIPRDIIIEAG
                     YGDYFTHGIGHGIGLDIHEEPYFSQTSTETIKTGMALTDEPGIYIEGKYGVRIEDDIL
                     ITETGCELLTLAPKELIVI"
     gene            47827..48225
                     /gene="spx"
                     /locus_tag="VYO11_000052"
     CDS             47827..48225
                     /gene="spx"
                     /locus_tag="VYO11_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HEV1594686.1"
                     /translation="MIKIYTVSSCTSCKKAKTWLNAHQLSYKEQNLGKEGITREELLD
                     ILTKTDNGIASIVSSKNRYAKALGVDIEDLSVNEVLNLIMETPRILKSPILVDEKRLQ
                     VGYKEDDIRAFLPRSVRNVENAEARLRAAL"
     gene            48291..48860
                     /locus_tag="VYO11_000053"
     CDS             48291..48860
                     /locus_tag="VYO11_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEV1594687.1"
                     /translation="MKKIVLVSLAFLFVLVGCGQKKETGPATKTEKDTLQSALPVIEN
                     AEKNTVVTKTLVLPKSDDGSQQTQTITYKDKTFLSLTIQQKRPVSDELKTYIDQHGVE
                     ETQKALLEAEEKDKSIIEARKLAGFKLETKLLSATELQTTTSFDFQVLDVKKASQLEH
                     LKNIGLENLLKNEPSKYISDRLANGATEQ"
     gene            48947..49213
                     /locus_tag="VYO11_000054"
     CDS             48947..49213
                     /locus_tag="VYO11_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HEV1594688.1"
                     /translation="MGFTEETVRFKLDDSNKKEISETLTDVYASLNDKGYNPINQIVG
                     YVLSGDPAYVPRYNNARNQIRKYERDEIVEELVRYYLKGQGVDL"
     gene            49217..49636
                     /gene="ruvX"
                     /locus_tag="VYO11_000055"
     CDS             49217..49636
                     /gene="ruvX"
                     /locus_tag="VYO11_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HEV1594689.1"
                     /translation="MRIMGLDVGSKTVGVAISDPLGFTAQGLEIIQINEEQGQFGFDR
                     VKELVDTYKVERFVVGLPKNMNNTSGPRVEASQAYGAKLEEFFGLPVDYQDERLTTVA
                     AERMLIEQADISRNKRKKVIDKLAAQLILQNYLDRKF"
     gene            49652..49957
                     /locus_tag="VYO11_000056"
     CDS             49652..49957
                     /locus_tag="VYO11_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HEV1594690.1"
                     /translation="MSHDHNHDHEERELITLVDEQGNETLFEILLTIDGKEEFGKNYV
                     LLVPVNAEEDEDGQVEIQAYSFIENEDGTEGELQPIPEDSEDEWNMIEEVFNSFMEE"
     gene            50216..51466
                     /locus_tag="VYO11_000057"
     CDS             50216..51466
                     /locus_tag="VYO11_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000464354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HEV1594691.1"
                     /translation="MFEVEEWLHSRIGLNFRSGLGRMQQAVDLLGNPEQSYPIIHVTG
                     TNGKGSTIAFMRELFMGHGKKVATFTSPHIVSINDRICINGQPIADADFIRLADQVKE
                     MEKTLLQTPDQLSFFELLTLVAFLYFREQEVDLVLLEVGIGGLLDTTNVVTGELAVIT
                     SIGLDHQETLGDSLEAIAEQKAGIFKAGKKAVIAKLPPEARLICQKKAESLAVDLYQA
                     GQDFSVLNGDFSSSLLNLSQLNIGLEGAYQQENAALALQTFLLFMGERKEAIDEQAVR
                     KTLEQTHWAGRLERIRPQIYLDGAHNLPALTRLVEFIKEKEQEGYRPQILFGSLKRKD
                     YQGMLGYLTENLPQVELKMTGFDYQGSLDETDVTGYHVIPSYREFISSFEERADAQDL
                     LFVTGSLYFISEVRGYLLDREQIN"
     gene            51463..52005
                     /locus_tag="VYO11_000058"
     CDS             51463..52005
                     /locus_tag="VYO11_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipocalin/fatty acid-binding family protein"
                     /protein_id="HEV1594692.1"
                     /translation="MTPFFELVILGELLVRENFSKLVAERKFIMKLKRFTLSLASLAS
                     FSLLVACSQRAQQVQQPVAQQVQQPAQQNTNTANAGGNQNQAAPVQNQPVAQPTDIDG
                     TYTGQDDGDRITLVVTGTTGTWTELESDGDQKVKQVTFDSANQRMIIGDDVKIYTVNG
                     NQIVVDDMDRDPSDQIVLTK"
     gene            52151..53683
                     /gene="cls"
                     /locus_tag="VYO11_000059"
     CDS             52151..53683
                     /gene="cls"
                     /locus_tag="VYO11_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000877342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HEV1594693.1"
                     /translation="MKYRKFQLLMSKYGFSLSIMLLELCLVFGLFLYLGRMAPILWIT
                     VLILLSIITIISIVNRNTTPENKVTWLLVAFVPVFGPLLYLMFGERRLSKKEIKQLKK
                     LGSMHFQEANSQLLKEKLKESDKAAYGVIKSLLSMDTNADIYDQTASTFFPNGEAMWK
                     KMVEDLKKAEKFIFLEYYIIEEGLMWNRILDILEQKVAQGVEVKMLYDDIGCMATLTG
                     DYAHRLRQLGIEAHKFNKVIPRLTVAYNNRDHRKILIVDGQIAYTGGVNLADEYINHV
                     ERFGYWKDSGIRLDGLAVKALTRLFLTTWYINRGEISDFDQYHLENHSIPSDGLTIPY
                     GSGPKPIFRAQVGKKVYQSLINQATESVYITTPYLIIDYDLTETIKNAAMRGVDVRII
                     TPYIPDKKFIQLVTRGAYPDLLSAGVRIYEYSPGFIHSKQMLVDEDFAVVGTINLDYR
                     SLVHHYENAVLLYKTPSIREIARDFRNIFADSQEVYPHSIKTSWYQKLVKEIAQLFAP
                     IL"
     gene            53761..53904
                     /locus_tag="VYO11_000060"
     CDS             53761..53904
                     /locus_tag="VYO11_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000956126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1594694.1"
                     /translation="MLTKEEVNDMIEFKQTHLHRFREIETFVKLCKKSLKQPSQADNP
                     RTF"
     gene            53941..55479
                     /locus_tag="VYO11_000061"
     CDS             53941..55479
                     /locus_tag="VYO11_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
                     /protein_id="HEV1594695.1"
                     /translation="MSVYGRVEEVHKENREPLEYQIEQESHHRESSRLPLVKILLWST
                     LVTGITLGVPLLLDLMSAQEVQDFYAGWALHQTGKIYSDYYGSQGLLYYLLTYVSQGG
                     FFFAIFEWLALVAGGFFLFRSADTLTEQGDQAGHLVTIFYMLVTGLAFGGGYATLLAL
                     PFLFAAFSLVAAYLSNPSHDKGFVRIGLALAGGFFFAPLSSLLFIAVVSLGLLVFNLG
                     HRRFAHGFYQFLAVALGFSLVFYPTAYYSAATGSFGDAISGIRYPIDSIRFDFTSKIL
                     ENMFFYGLLSLGLGFVVCIFLGLFQSKPFKLYVISVPASLVVILGLILLFFSQEPLHA
                     SYLMVVFPVFLLLLVTNIKSQQRGRSARRSRRETPVSLWSRFFKGNLYLLVFGFVYLL
                     SVPFLMKFVLYPVPYQERNRLADLVKEETNTEDAIYAWDDTATLYRKSERLSPSAILS
                     PLHYTATEENRNKLLNDLKEKQPKVIVVNDKVVVWSEVETLLKENYQQVKTDYSEFKV
                     YKIK"
     gene            55599..57806
                     /gene="nrdD"
                     /locus_tag="VYO11_000062"
     CDS             55599..57806
                     /gene="nrdD"
                     /locus_tag="VYO11_000062"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004239081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HEV1594696.1"
                     /translation="MIALEEKITILPTLFVEKRDGRRVVFDVDKIDKALHKAADKVMD
                     VTPLVEKCLNDLTERIITEIHSRFPQGIKIYEIQNIVEHELLEAKEYALAEEYITYRT
                     QRDFERSKATDINFSIHKLLNKDQTVVNENANKDSDVFNTQRDLTAGIVGKSIGLQML
                     PKHVANAHQKGDIHYHDLDYSPYTPMTNCCLIDFKGMLENGFKIGNAEVESPKSIQTA
                     TAQISQIIANVASSQYGGCSADRIDEILAPYAEKNYQKHLKDAEEWVLPEKQEDYAWK
                     KAQKDIYDAMQSLEYEINTLFTSNGQTPFTSLGFGLGTSRFEREIQKAILNIRIKGLG
                     SEHRTAIFPKLIFTLKRGLNLEEGTPNYDIKQLALECATKRMYPDVLSYDKIVDLTGS
                     FKVPMGCRSFLQGWKDENGVEVNSGRMNLGVVTVNLPRIALESEGDMNKFWEIFNERM
                     NIAEDALVYRVERTKEATPANAPILYQYGAFGHRLGKEESVDQLFKNRRATVSLGYIG
                     LYEVATVFFGNSWESNPDAKEFTLDIIHDMKRRVEEWSDQYGYHFSIYSTPSESLTDR
                     FCRLDIDKFGSIPDITDKEYYTNSFHYDVRKNPTPFEKLDFEKVYPEAGASGGFIHYC
                     EYPVLQQNPKALEAVWDYAYDRVGYLGTNTPIDRCYKCDFEGDFEPTERGFACPNCGN
                     SDPKTVDVVKRTCGYLGNPQARPMVNGRHKEIAARVKHMNGSTIKIAGHQVTN"
     gene            57818..57958
                     /locus_tag="VYO11_000063"
     CDS             57818..57958
                     /locus_tag="VYO11_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1594697.1"
                     /translation="MGKYQLDDKGRAQVTRYHEKHSKGGAGKKERLLSFREQFLNKNK
                     KK"
     gene            58002..58508
                     /locus_tag="VYO11_000064"
     CDS             58002..58508
                     /locus_tag="VYO11_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000423399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1594698.1"
                     /translation="MELRRPRLADKKAVLDMMTEFEKSQSAHDGGFWDVEDFSYEEWL
                     EGNRNKEMGIWLPENRVPSIQFVLFGESGCALGFLNLRLRLNEGLLNYAGHIGYSIRP
                     SERGKGYAKETLRQGLQVAKEKNIKKALVTCSVNNPASRAVILANGGIFEDARNGVER
                     YWIEVANE"
     gene            58501..59091
                     /gene="nrdG"
                     /locus_tag="VYO11_000065"
     CDS             58501..59091
                     /gene="nrdG"
                     /locus_tag="VYO11_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001064213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HEV1594699.1"
                     /translation="MNNPKPQEWKSEELSQGRIIDYKAFNFVDGEGVRNSLYVAGCMF
                     HCEGCYNVATWSFNAGIPYTAELEEQIMADLAQPYVQGLTLLGGEPFLNTGILLPLVK
                     RIRKELPDKDIWSWTGYTWEEMMLETPDKLELLSLIDILVDGRYDRTKRNLMLQFRGS
                     SNQRIIDVQKSLKSGQVVIWDKLNDGKESYEQVKRE"
     gene            59088..59705
                     /locus_tag="VYO11_000066"
     CDS             59088..59705
                     /locus_tag="VYO11_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribulokinase"
                     /protein_id="HEV1594700.1"
                     /translation="MKKKDLVDQLVSEIETGKVRTLGIYGHGASGKSTFAQELYQALD
                     STTVNLLETDPYITSGRHLVVPKDAPNQKVTASLPVAHELESLQRDILALQAGMDVLT
                     IEEPWKASEVLSGVKPILIVEGMSVGFLPKELFEKTICFYTDEETELKRRLARDTTVR
                     NRDASFILASHQMRREQYLRYYKETESKADILVDQSEDKFDVKRT"
     gene            59971..60279
                     /gene="rpsJ"
                     /locus_tag="VYO11_000067"
     CDS             59971..60279
                     /gene="rpsJ"
                     /locus_tag="VYO11_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HEV1594701.1"
                     /translation="MANKKIRIRLKAYEHRTLDTAAAKIVESATRTGAQVAGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTQKTVDALMKLDLPSGVNVEIKL
                     "
     gene            60496..61122
                     /gene="rplC"
                     /locus_tag="VYO11_000068"
     CDS             60496..61122
                     /gene="rplC"
                     /locus_tag="VYO11_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HEV1594702.1"
                     /translation="MTKGILGKKVGMTQIFTEAGELIPVTVIEATPNVVLQVKTVETD
                     GYNAIQVGFDDKREVLSNKPAKGHVAKANTAPKRFIREFKNVEGLEVGAEITVETFAA
                     GDVVDVTGTSKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKGKNLAG
                     RMGGDRVTIQNLEVVQVVPEKNVILIKGNVPGAKKSLITIKSAVKAGK"
     gene            61147..61770
                     /gene="rplD"
                     /locus_tag="VYO11_000069"
     CDS             61147..61770
                     /gene="rplD"
                     /locus_tag="VYO11_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HEV1594703.1"
                     /translation="MANVTLFDQTGKEAGQVVLNDAVFGIEPNESVVFDVIISQRASL
                     RQGTHAVKNRSAVSGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYGYKLP
                     QKVRRLALKSVYSEKVAENKFVAVDALSFTAPKTAEFAKVLAALSIDSKVLVILEEGN
                     EFAALSARNLPNVKVATATTASVLDIANSDKLLVTQAAISKIEEVLA"
     gene            61770..62066
                     /locus_tag="VYO11_000070"
     CDS             61770..62066
                     /locus_tag="VYO11_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HEV1594704.1"
                     /translation="MNLYDVIKKPVITESSMAQLEAGKYVFEVDTRAHKLLIKQAVEA
                     AFEGVKVANVNTINVKPKAKRVGRYTGFTNKTKKAIITLTADSKAIELFAAEAE"
     gene            62084..62917
                     /gene="rplB"
                     /locus_tag="VYO11_000071"
     CDS             62084..62917
                     /gene="rplB"
                     /locus_tag="VYO11_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019790357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HEV1594705.1"
                     /translation="MGIRVYKPTTNGRRNMTSLDFAEITTSTPEKSLLVALKSKAGRN
                     NNGRITVRHQGGGHKRFYRLVDFKRNKDNVEAVVKTIEYDPNRSANIALVHYTDGVKA
                     YIIAPKGLEVGQRIVSGPEADIKVGNALPLANIPVGTLIHNIELKPGRGGELVRAAGA
                     SAQVLGSEGKYVLVRLQSGEVRMILGTCRATVGVVGNEQHGLVNLGKAGRSRWKGIRP
                     TVRGSVMNPNDHPHGGGEGKAPVGRKAPSTPWGKPALGLKTRNKKAKSDKLIVRRRNE
                     K"
     gene            63021..63302
                     /gene="rpsS"
                     /locus_tag="VYO11_000072"
     CDS             63021..63302
                     /gene="rpsS"
                     /locus_tag="VYO11_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HEV1594706.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQANDEKKKVIKTWSRRSTIFPSF
                     IGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYKGHAADDKKTRRK"
     gene            63314..63658
                     /gene="rplV"
                     /locus_tag="VYO11_000073"
     CDS             63314..63658
                     /gene="rplV"
                     /locus_tag="VYO11_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HEV1594707.1"
                     /translation="MAEITSAKAMARTVRVSPRKSRLVLDNIRGKSVADAIAILTFTP
                     NKAAEIILKVLNSAVANAENNFGLDKANLVVSEAFANEGPTMKRFRPRAKGSASPINK
                     RTAHITVAVAEK"
     gene            63671..64324
                     /gene="rpsC"
                     /locus_tag="VYO11_000074"
     CDS             63671..64324
                     /gene="rpsC"
                     /locus_tag="VYO11_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HEV1594708.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYADYLHEDLAIRKFVQK
                     ELADAAVSTIEIERAVNKVNVSLHTAKPGMVIGKGGANVDALRAKLNKLTGKQVHINI
                     IEIKQPDLDAHLVGEGIARQLEQRVAFRRAQKQAIQRAMRAGAKGIKTQVSGRLNGAD
                     IARAEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEVLPARKNTKGGK"
     gene            64328..64741
                     /gene="rplP"
                     /locus_tag="VYO11_000075"
     CDS             64328..64741
                     /gene="rplP"
                     /locus_tag="VYO11_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003029477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HEV1594709.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQATTSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKV
                     MFEIAGVSEEIAREALRLASHKLPVKCKFVKREAE"
     gene            64751..64957
                     /locus_tag="VYO11_000076"
     CDS             64751..64957
                     /locus_tag="VYO11_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HEV1594710.1"
                     /translation="MKLNEVKEFVKELRGLSQEELAKRENELKKELFELRFQAATGQL
                     EQTARLKEVKKQIARIKTVQSEAK"
     gene            64982..65242
                     /gene="rpsQ"
                     /locus_tag="VYO11_000077"
     CDS             64982..65242
                     /gene="rpsQ"
                     /locus_tag="VYO11_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HEV1594711.1"
                     /translation="MERNNRKVLVGRVVSDKMDKTITVVVETKRNHPVYGKRINYSKK
                     YKAHDENNVAKEGDIVRIMETRPLSATKRFRLVEVVEEAVII"
     gene            65268..65636
                     /gene="rplN"
                     /locus_tag="VYO11_000078"
     CDS             65268..65636
                     /gene="rplN"
                     /locus_tag="VYO11_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HEV1594712.1"
                     /translation="MIQTETRLKVADNSGAREILTIKVLGGSGRKFANIGDVIVASVK
                     QATPGGAVKKGDVVKAVIVRTKSGARRADGSYIKFDENAAVIIREDKTPRGTRIFGPV
                     ARELREGGFMKIVSLAPEVL"
     gene            65714..66019
                     /gene="rplX"
                     /locus_tag="VYO11_000079"
     CDS             65714..66019
                     /gene="rplX"
                     /locus_tag="VYO11_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HEV1594713.1"
                     /translation="MFVKKGDKVRVIAGKDKGTEAVVLTALPKVNKVIVEGVNIVKKH
                     QRPTNELPQGGIIEKEAAIHVSNVQVLDKNGVAGRVGYKFVDGKKVRYNKKSGEVLD"
     gene            66043..66585
                     /gene="rplE"
                     /locus_tag="VYO11_000080"
     CDS             66043..66585
                     /gene="rplE"
                     /locus_tag="VYO11_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HEV1594714.1"
                     /translation="MANRLKEKYLNEVVPALTEQFNYSSVMAVPKVDKIVLNMGVGEA
                     VSNAKSLEKAAEELALISGQKPLITKAKKSIAGFRLREGVAIGAKVTLRGERMYEFLD
                     KLVSVSLPRVRDFHGVPTKSFDGRGNYTLGVKEQLIFPEINFDDVDKTRGLDIVIVTT
                     ANTDEESRALLTGLGMPFAK"
     gene            66603..66872
                     /gene="rpsN"
                     /locus_tag="VYO11_000081"
     CDS             66603..66872
                     /gene="rpsN"
                     /locus_tag="VYO11_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HEV1594715.1"
                     /translation="MAKKSMVAREAKRQKIVDRYAEKRAALKAAGDYEGLSKLPRNAS
                     PTRLHNRCRVTGRPHSVYRKFGLSRIAFRELAHKGQIPGVTKASW"
     gene            67157..67555
                     /gene="rpsH"
                     /locus_tag="VYO11_000082"
     CDS             67157..67555
                     /gene="rpsH"
                     /locus_tag="VYO11_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009754342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HEV1594716.1"
                     /translation="MVMTDPIADFLTRIRNANQAKHEVLEVPASNIKKGIAEILKREG
                     FVKNVEIIEDDKQGVIRVFLKYGPNGEKVITNLKRVSKPGLRVYKKREDLPKVLNGLG
                     IAILSTSEGLLTDKEARQKNVGGEVIAYVW"
     gene            67747..68283
                     /gene="rplF"
                     /locus_tag="VYO11_000083"
     CDS             67747..68283
                     /gene="rplF"
                     /locus_tag="VYO11_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HEV1594717.1"
                     /translation="MSRIGNKVIVLPAGVELANNDNVVTVKGPKGELTREFSKDIEIR
                     VEGTEITLHRPNDSKEMKTIHGTTRALLNNMVVGVSEGFKKELEMRGVGYRAQLQGSK
                     LVLAVGKSHPDEVEAPEGITFELPNPTTIVVSGISKEVVGQTAAYVRSLRSPEPYKGK
                     GIRYVGEFVRRKEGKTGK"
     gene            68367..68723
                     /gene="rplR"
                     /locus_tag="VYO11_000084"
     CDS             68367..68723
                     /gene="rplR"
                     /locus_tag="VYO11_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HEV1594718.1"
                     /translation="MISKPDKNKLRQKRHRRVRGKLSGTADRPRLNVFRSNTGIYAQV
                     IDDVAGVTLASASTLDKEVSKGTKTEQAVAVGKLVAERANAKGISEVVFDRGGYLYHG
                     RVKALADAARENGLKF"
     gene            68741..69235
                     /gene="rpsE"
                     /locus_tag="VYO11_000085"
     CDS             68741..69235
                     /gene="rpsE"
                     /locus_tag="VYO11_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HEV1594719.1"
                     /translation="MAFKDNAVELEERVVAVNRVTKVVKGGRRLRFAALVVVGDHNGR
                     VGFGTGKAQEVPEAIRKAVDDAKKNLIEVPMVGTTIPHEVLSEFGGAKVLLKPAVEGS
                     GVAAGGAVRAVVELAGVADITSKSLGSNTPINIVRATVEGLKQLKRAEEIAALRGISV
                     SDLA"
     gene            69207..69431
                     /gene="rpmD"
                     /locus_tag="VYO11_000086"
     CDS             69207..69431
                     /gene="rpmD"
                     /locus_tag="VYO11_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012386624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HEV1594720.1"
                     /translation="MVFQFLIWHKKGDKMAQIKITLTKSPIGRIPSQRKTVVALGLGK
                     LNSSVIKEDNAAIRGMITAVSHLVTVEEVN"
     gene            69576..70016
                     /gene="rplO"
                     /locus_tag="VYO11_000087"
     CDS             69576..70016
                     /gene="rplO"
                     /locus_tag="VYO11_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004225266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HEV1594721.1"
                     /translation="MKLHELKPAEGSRKVRNRVGRGTSSGNGKTSGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNINAKEYAIVNLDQLNVFEDGAEVTPVVLIEAGIV
                     KAEKSGIKILGNGELTKKLTVKAAKFSKSAEEAITAKGGSVEVI"
     gene            70029..71339
                     /gene="secY"
                     /locus_tag="VYO11_000088"
     CDS             70029..71339
                     /gene="secY"
                     /locus_tag="VYO11_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HEV1594722.1"
                     /translation="MFFKLLREALKVKQVRSKILFTIFIVLVFRIGTSITVPGVNANS
                     LNALSGLSFLNMLSLVSGNALKNFSIFALGVSPYITASIVVQLLQMDILPKFVEWGKQ
                     GEVGRRKLNQATRYIALVLAFVQSIGITAGFNTLAGAQLIKTALTPQVFLTIGIILTA
                     GSMIVTWLGEQITDKGYGNGVSMIIFAGIVSSIPEMIQGIYVDYFVNVPSSRITSSII
                     FVIILIITVLLIIYFTTYVQQAEYKIPIQYTKVAQGAPSSSYLPLKVNPAGVIPVIFA
                     SSITAAPAAILQFLSATGHDWAWVRVAQEMLATTSPTGIAMYALLIILFTFFYTFVQI
                     NPEKAAESLQKSGAYIHGVRPGKGTEEYMSKLLRRLATVGSLFLGVISILPIAAKDVF
                     GLSDVVAFGGTSLLIIISTGIEGIKQLEGYLLKRKYVGFMDRTE"
     gene            71490..72128
                     /locus_tag="VYO11_000089"
     CDS             71490..72128
                     /locus_tag="VYO11_000089"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HEV1594723.1"
                     /translation="MNLLIMGLPGAGKGTQAAKIVEQFHVAHISTGDMFRAAMANQTE
                     MGVLAKSYIDKGELVPDEVTNGIVKERLSQDDIKETGFLLDGYPRTIEQAHALDKTLA
                     ELGIELEGIINIEVNPDSLLERLSGRIIHCVTGETFHKVFNPPVDYKEEDYYQREDDK
                     PETVKRRLDVNIAQGEPIIAHYRAKGLVHDIEGNQDINDVFSDIEKVLTNLK"
     gene            72245..72463
                     /gene="infA"
                     /locus_tag="VYO11_000090"
     CDS             72245..72463
                     /gene="infA"
                     /locus_tag="VYO11_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HEV1594724.1"
                     /translation="MAKDDVIEVEGKVVDTMPNAMFTVELENGHQILATVSGKIRKNY
                     IRILAGDRVTVEMSPYDLTRGRITYRFK"
     gene            72488..72604
                     /gene="rpmJ"
                     /locus_tag="VYO11_000091"
     CDS             72488..72604
                     /gene="rpmJ"
                     /locus_tag="VYO11_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HEV1594725.1"
                     /translation="MKVRPSVKPICEYCKVIRRNGRVMVICPANPKHKQRQG"
     gene            72622..72987
                     /gene="rpsM"
                     /locus_tag="VYO11_000092"
     CDS             72622..72987
                     /gene="rpsM"
                     /locus_tag="VYO11_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HEV1594726.1"
                     /translation="MARIAGVDIPNDKRVVISLTYVYGIGLATSKKILAAAGISEDVR
                     VRDLTSDQEDAIRREVDAIKVEGDLRREVNLNIKRLMEIGSYLGIRHRRGLPVRGQNT
                     KNNARTRKGKAVAIAGKKK"
     gene            73005..73388
                     /gene="rpsK"
                     /locus_tag="VYO11_000093"
     CDS             73005..73388
                     /gene="rpsK"
                     /locus_tag="VYO11_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HEV1594727.1"
                     /translation="MAKPTRKRRVKKNIESGIAHIHATFNNTIVMITDVHGNAIAWSS
                     AGALGFKGSRKSTPFAAQMASEAAAKSAQEHGLKSVEVTVKGPGSGRESAIRALAAAG
                     LEVTAIRDVTPVPHNGARPPKRRRV"
     gene            73431..74366
                     /locus_tag="VYO11_000094"
     CDS             73431..74366
                     /locus_tag="VYO11_000094"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HEV1594728.1"
                     /translation="MIEFEKPNITKIDENKDYGKFVIEPLERGYGTTLGNSLRRVLLA
                     SLPGAAVTSINIDGVLHEFDTVPGVREDVMQIILNIKGIAVKSYVEDEKIIELDVEGP
                     AEVTAGDILTDSDIEIVNPDHYLFTIGEGSSLKATMTVNSGRGYVPADENKKDNAPVG
                     TLAVDSIYTPVTKVNYQVEPARVGSNDGFDKLTLEILTNGTIIPEDALGLSARILTEH
                     LDLFTNLTEIAKSTEVMKEADTESDDRILDRTIEELDLSVRSYNCLKRAGINTVHDLT
                     EKSEAEMMKVRNLGRKSLEEVKLKLIDLGLGLKDK"
     gene            74378..74764
                     /gene="rplQ"
                     /locus_tag="VYO11_000095"
     CDS             74378..74764
                     /gene="rplQ"
                     /locus_tag="VYO11_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002887523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HEV1594729.1"
                     /translation="MAYRKLGRTSSQRKAMLRDLTTDLLINESIVTTEARAKEIRKTV
                     EKMITLGKRGDLHARRQAAAFVRNEIASENYDEATDKYTSTTALQKLFSEIAPRYAER
                     NGGYTRILKTEPRRGDAAPMAIIELV"
     gene            75029..75295
                     /locus_tag="VYO11_000096"
     CDS             75029..75295
                     /locus_tag="VYO11_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002905356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HEV1594730.1"
                     /translation="MKAIITVVGKDKSGIVAGVSGKIAELGLNIDDISQTVLDEYFTM
                     MAVVSSDEKQDFTYLRNEFEAFGQTLNVKINIQSAAIFEAMYNI"
     gene            75305..76642
                     /locus_tag="VYO11_000097"
     CDS             75305..76642
                     /locus_tag="VYO11_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PFL family protein"
                     /protein_id="HEV1594731.1"
                     /translation="MDIRQVTETIAMIEEQNFDIRTITMGISLLDCIDPNINRAAEKI
                     YQKITTKAANLVAVGDEIAAELGIPIVNKRVSVTPISLIGAATDATDYVVLAKALDKA
                     AKEIGVDFIGGFSALVQKGYQKGDEILINSIPRALAETDKVCSSVNIGSTKSGINMTA
                     VADMGRIIKETANLSDMGVAKLVVFANAVEDNPFMAGAFHGVGEADVIINVGVSGPGV
                     VKRALEKVRGQSFDVVAETVKKTAFKITRIGQLVGQMASERLGVEFGIVDLSLAPTPA
                     VGDSVARVLEEMGLETVGTHGTTAALALLNDQVKKGGVMACNQVGGLSGAFIPVSEDE
                     GMIAAVQNGSLNLEKLEAMTAICSVGLDMIAIPEDTPAETIAAMIADEAAIGVINMKT
                     TAVRIIPKGREGDMIEFGGLLGTAPVMKVNGASSVDFISRGGQIPAPIHSFKN"
     gene            76886..77578
                     /locus_tag="VYO11_000098"
     CDS             76886..77578
                     /locus_tag="VYO11_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEV1594732.1"
                     /translation="MVKVRLYLVRHGKTMFNTIGRAQGWSDTPLTAEGERGIQELGIG
                     LRESDLQFERAYSSDSGRTIQTMGIILEELGLQGKIPYRMDKRIREWCFGSFDGAYDG
                     DLFMGIIPRIFNVDHVHQLSYAELAEGLVEVDTAGWAEGWEKLSGRIKEGFEMIAKEM
                     EDQGGGNALVVSHGMTIGTIVYLINGMHPHGLDNGSVTILEYEDGQFRVEVVGDRSYR
                     ELGREKMEEGSI"
     gene            complement(77681..79316)
                     /locus_tag="VYO11_000099"
                     /pseudo
     CDS             complement(77681..79316)
                     /locus_tag="VYO11_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520796.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
     gene            complement(79306..80397)
                     /locus_tag="VYO11_000100"
                     /pseudo
     CDS             complement(79306..80397)
                     /locus_tag="VYO11_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001289362.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            complement(80410..81531)
                     /locus_tag="VYO11_000101"
                     /pseudo
     CDS             complement(80410..81531)
                     /locus_tag="VYO11_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931989.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
     gene            complement(81748..81891)
                     /locus_tag="VYO11_000102"
     CDS             complement(81748..81891)
                     /locus_tag="VYO11_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001833196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HEV1594733.1"
                     /translation="MAESPNSPLSAISDQVGFSDYKYFAKVFKKHLHISPKELKLLGR
                     IVK"
     gene            complement(81990..82223)
                     /locus_tag="VYO11_000103"
     CDS             complement(81990..82223)
                     /locus_tag="VYO11_000103"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HEV1594734.1"
                     /translation="MQYGAVDFLSKPIDTKELTECLQKIVLRLQISTSQETPFLEEYQ
                     TLLTSIQQVDTQNQIIQQIISFVHKHYAEHYYC"
     gene            complement(82272..82499)
                     /locus_tag="VYO11_000104"
     CDS             complement(82272..82499)
                     /locus_tag="VYO11_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HEV1594735.1"
                     /translation="MFKLIIVEDEHLIRKWLEIAVDYSALGIQVVGTASHGQEGMKLI
                     QEKETHICLNRHHNANYGCFYDVQSHSYSFL"
     gene            complement(82503..82886)
                     /locus_tag="VYO11_000105"
     CDS             complement(82503..82886)
                     /locus_tag="VYO11_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEV1594736.1"
                     /translation="MIHKIRFEHFSYDIVCPETVDNQPIPKLFLLPLVENAIKHGMQY
                     RIDLHIDIHITLEADSLTFLVKDNAGGLTKQERFAILDSLESPHTQHGIMNSYKQLSN
                     FFSDVQLDLGVNRQGETWVKFVTKD"
     gene            complement(83219..83995)
                     /locus_tag="VYO11_000106"
     CDS             complement(83219..83995)
                     /locus_tag="VYO11_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000406168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HEV1594737.1"
                     /translation="MEISKGIIFNIQHFSIHDGPGIRTTVFLKGCPLRCPWCSNPESQ
                     RMKPEKMKDAQREKFTLVGEEKTVEEIITEVLKDKEFYEESGGGLTLSGGEIFAQFEF
                     AKAILKSAKEHHIHTAIETTAFVDHEKFIDLIQYVDFIYTDLKHYNSIKHKKVTGVFN
                     QMIIKNIHYAFSQNKTIVLRIPVIPNFNNSLEDAEKFATLFNSLNIDQVQLLPFHQFG
                     ENKYRLLNRKYEMDGINALHPEDLIDYQKVFLNHHINCYF"
     gene            84117..84863
                     /locus_tag="VYO11_000107"
     CDS             84117..84863
                     /locus_tag="VYO11_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEV1594738.1"
                     /translation="MKRLEQIIKLVSEYEKIDVNTLSEKLNVSKVTIRKDLDKLESKG
                     LLHREHGYAVLNSGDDLNVRLSINYEIKRKIVQEAVKLVSDNETIMIESGSTCALLAE
                     EICKQKRNVTIVTNSFFIANFVRAYDSCRIIVLGGEFQKDSQVTVGPLLKEMIQTFHV
                     HQAFVGTDGYDKEMGFTGKDLMRSEVVQYISAASDKVIVLTDSSKFDKRGTVRRFALS
                     QVYEVITDEKLSKQNIATLENAGIMVKVVS"
     gene            84876..85856
                     /locus_tag="VYO11_000108"
     CDS             84876..85856
                     /locus_tag="VYO11_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001070834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HEV1594739.1"
                     /translation="MNQDRNKLLSKIAYLYYIENLNQSQIAAKLGIYRTSISRMLTEA
                     RNAGIVKIEIENFDTNMFKLENYVKEKYGLESLEIIPNEFDDNPTILSERISQVAAGV
                     LRNLIDDNMKIGFSWGKSLSNLVDLIHSKSVRNVHFYPLAGGPSHIHAKYHVNTLIYE
                     MSRKFHGECTFMNATIVQENKLLADGILQSRYFENLKNSWKDLDIAVVGIGDFSNKGK
                     HQWLDMLTEDDFKELTKVKTVGEICCRFFDSKGKEVYENLQERTIAISLEDLKNIPQS
                     LAVAYGDTKVSSILSVLRANLVNHLITDKNTILKVLEEDGDLTFREILGE"
BASE COUNT        26237 a        15700 c        18467 g        25543 t
ORIGIN      
        1 ttgaactatt tataaaacaa agtgatctaa ttgttgcaaa tagatgggat agggaccttg
       61 aagcttataa agataaagtt tacacaaggg ggatctggat aagagattaa ctattgatat
      121 taaaaaggca ataatttata aaatttgtac aaaaaaatgt taaattttca cattttcata
      181 gtatactgtt taatagaaag taggttcttt gtaaccgctc cattataaaa tcctttcact
      241 cttccggtat actattagga aaaacataac tggaggatat tttgagctca cacctcatcg
      301 ttccagtggc tgttccccaa gctcgtgtac tgcccaaaaa agttagacat tctatttaga
      361 acgaggattg agttctgtat tgtacaaggc tcggtccttt tagagtcagc ttaaggctgg
      421 ctttttcaat caccaaagtg tcagaatgtt ttgacaaatg aacacaaata atgatataat
      481 atgcaaaagc taggaggtgg taggatgatt gaaaaaatgg aactggggga attttacaag
      541 gaattgcgct tggcgagaaa gctcaagcag tcagatgtgg cttgtgctgg actaacagcc
      601 tctcagttgt ccaagtttga actaggacag tctatgctgt ctgcagacaa gctgatccta
      661 gccatccaag ggatcaatat gaattttgat gagtttgggc acaaactcaa caactatcaa
      721 gaatctccac atatgcgaat tggtagaagg gttgtggatt gcttttccca tcaggatata
      781 gctgctttag agcagctatt ggaggaagtc gatcaagaac agatggcgca gacctatcgt
      841 cgtttgaatg ccattgtgat taaaaatgca ctccattcct tagataaaag ctacccgcta
      901 acagaggagg atagcgagtt tttgactacc tacctctacg ctattgagtc ttggacctgg
      961 tttgaactct atcttttttg caatactatg cccttcttga gcaatcaaga tctgatcttt
     1021 ttatcaacct ccttactcga aaaatccaag gaatttaaag agttagtaca caatcgatgg
     1081 tatatgaaaa gtggttatct taatatcatc tcagaactta tggagcgcaa gctattttct
     1141 tatattccaa tctttgaagc tgagctggag cgcatgctcc gtccatacga tgtttttgaa
     1201 aaagtattgt ggcagttttt aaagaaaatg cagatttttc ttcaaaccaa aggaagcaat
     1261 caaaaagaga ttgaacactt tatccaatct ctgcaagtat tagaaaatcc acaattgaca
     1321 gccctttttg aattgcgttt gcagcaatac aaagagctta tcgattagtt agaaatggga
     1381 aaaagataat aatatcagca acgatcgtca ataatgttaa aacttgtttc ttcatattac
     1441 ttccctcctc attagtaata actttattat accagggaaa taatcaaatc taccaaaatc
     1501 gcaaatctga aatttctata agaaaaaata tcaaatatgc gattttctaa aataagccaa
     1561 tttccgtgtt atactgtcct tgtaaaacat ttgaagcaaa tcctaggtcg cagaagtggt
     1621 ttacaaatga agataattga aggagtgtaa aagatgttaa atttacaatt tgcagaaaca
     1681 atggaattga cagaagctga gttgcaagat gttagaggag gcaacctcgt aaattctatg
     1741 ggaggtggtg gaagaagtgg tatatctggt tggggcgtcc caggaattta ccctggttgg
     1801 ggcaatcaag ggatgagtcc taatcgtgga gcttttgatt ggactataga tttagcagat
     1861 ggattgtttg gccgccgtag aagataggct cttataggag ataataggat gaagaaaatg
     1921 aaagaagtga aatttcacct agcaactggc ttgttgattt tgacttatta cctcattttt
     1981 aatgtcacat cagacttaga ttttatggtt gctttgtctg ataatatgta ctatgtgttc
     2041 caagttttat tggtacttat tctgggaact atagctacaa ttgcttttgt caaaagtgaa
     2101 cattggaaag agtgtggtcg tttccagttt cgttggtctt acctgggtgt tttccttctt
     2161 tcttttttct tattgttcgt gtgggcaaat ctaacaacct atatctttcc tcgtacccag
     2221 aatggaagta cagtcgtaga agtagccacc agtttaacag gaattagcta ttttgttacg
     2281 cgaatacttt atactagtat tatcgcacct gtatcagaag aggttgtttg tcgtggtctt
     2341 ttgatgacaa gtttatctaa agttaataga tactatcttg atgttcttgt ttccgctgcc
     2401 atatttggcg ctatgcatgt tttgcagtat ggttggataa cgacagattt cataaagtat
     2461 tttggaatgg gcttgatatt ttgtatgatg tttcgctaca cccgatccat ctattgggct
     2521 atagctctgc atgcttcatg gaatagcttc ttactcattg ttactttatt ggtatttgga
     2581 tattagaaag gtgatatatg aaaaagataa tctcacaccg ctactttatt atagtttttc
     2641 tactagttat tgctgaccag aagttcagtg ttttagtttt acgcagcgac cttgttgctg
     2701 ggctatctga ctttgcctat tatctgtcgg atatgatgtt gaattttctt gtggttttat
     2761 ttgctcttat tgctatgatt tggtcgggga aatggcagaa aatcaatagt agaaagttta
     2821 aaggatccta tcttttctat tccttcctag ctctgcttgc ttttgttgct tggaattttg
     2881 tcaccttttt tcttttccca cctactcgaa atgaaatttc ttatcaacat gctgctccta
     2941 cttttacagg agctacggca tttttgatgt atttttttta tcctgtgatt gcaggtccca
     3001 tttttgaaga catgatttat cgtggattag tgatgactgc tctggaaaaa ggaaagaaat
     3061 gggggctaga tgtacttggt tccgctgttt tatttggggt ctcgcacatt agtaatcacg
     3121 gttgggtctt gacagacttt gtcttctata tgggtggagg tcttatattt gcagtcttat
     3181 ttagaatgac aaagtcaatt tattggccta ttggactgca tatagtctac aatggtattg
     3241 gtcagctttt gatgttactg taattttggt tgttagtagt atcgcggtct attcttgggg
     3301 aaagattccc atttgaattt aaaaaggagt tgtaatgaaa gtatttcttc aaaatagaga
     3361 ttttaggcaa ttaactatca atcagtggat ttcaacgctt ggggatacga ttttttatct
     3421 ggccttcctg aattatgtgg cagatgcgtc ttttgcccct ttggcgattt tacttatcac
     3481 gatttcagaa acccttcccc aagttctaca aatctttctg ggagttttgg cggattttca
     3541 acatcatcgt gtcttgaaat acacagtcat tagttttaca aaatttttgc tttactctat
     3601 agtgtcccta tcgctttcag ggcagtcttt ttccttgttg ctagtaacct ttatttgtct
     3661 gattaacctc ttgtctgaca cattgagtta tttttcaggc gccatgctca ctccgatttt
     3721 cattagaatt attgggcaag atcatctggc agaagctatt ggatttaaac agtcaactgt
     3781 tagtttagtg aaaacaatca gtaatatcct aggaggagtc ttactaggta ttctatccat
     3841 ccagtttatt tccttactga acgctcttac ctttttaatc gcatttttag gtatcctctt
     3901 cataaaaact gacctcttga aagtagaaaa aacgattagc tatcaagaag gactctctgt
     3961 aaaatccttt tgccagcatt tgctccaatc atcgaaattg atatggaata tgaataaggt
     4021 gctcttggtt ttgtttatta tctctactag tcaagcagtg ataaatgtta cagttcctgt
     4081 ctctactcta tttttgagga atcaaccctt tttgaattta caaacaggtc aatctcttgc
     4141 cttgctatcc acttttgaac tgtcagccct gattgtcgga agccttgtaa gtggctatct
     4201 gcaacatacc atttccataa aaacagctct ctatgcctca cttgtcatcc agttgcttct
     4261 tctagtagga tttgccacag ttcgttttga ctggattctc atctttagta ccttggatgc
     4321 ctttttcgca ggtgttctct ctcctagatt gcaagaactc gtctttaaac aaatacctga
     4381 ggagtcaatg ggagcagttc aatcttctat cagtgccatt acggttgttt tacctagctt
     4441 atttacaata tctttggtaa ccattgctac tagctttgga actctggcag ttagctttgt
     4501 tttattgcta tttcttctag ttgcctttgt tatgcttctg aatattcgtg aaagtattta
     4561 gtggagaatt tctataatat atgtttgaga ctggattgcc agtcttttta tgatggtcaa
     4621 aatcaacaga cttttttctc ttttctgaat gtgttatagt agactgaatc taaaatagta
     4681 cgaaacaatt gctaaaacat ttatagaaat taattttact ttcccaatcg atttgttcat
     4741 atcttatttc aatctgctat ataatagtcc atgctatggc tggattcttt tcagtctact
     4801 tatactcttc gaaactctct tcaaaccacg tcagcttcac cttgccgtag tacggttact
     4861 gacttcgtca gttctatcca caacctcaaa acggtgtttt gagctgactt cgtcagttct
     4921 atccacaatc tcaaaacggt gttttgagct gacttcgtca gttctatcca caacctcaaa
     4981 acggtgtttt gagcaacctg cggctagttt cctagtttgc tctttgattt tcattgagta
     5041 ttattaagac aatatgagga gaaagatgaa agaaaaagga ttttaggagg gggcgcaggc
     5101 agccatgcca acggctcttg gctatgtcag tatcggcctg gcctgtggga ctatcggtgc
     5161 gccctatgtg acacctgttg agatgggctt gatgagtctc tttgtttatg ctgggagtgc
     5221 ccagtttgcc atgttggcac tgattgtggt tcaagctcct gtggcagcta ttgctatgac
     5281 ggtttttcta atcaacttgc gtctcttttt gttgagttta cacgcatcga cttatttccg
     5341 tcataccagt ctttggtaca atatcggtat gtctagtatc ttgacagatg agacctatgg
     5401 cgttttgatg ggtgaattgg cccatacaga caaggtaaat cctatgtgga tgcacggaaa
     5461 caatcttaac agctatgtgg cttggtttgt ggggacagta gtcggaacgg atctgggtgg
     5521 cctgctacca aatccagaaa tctttggctt ggattttgcc ctggttggga tgtttattgg
     5581 tatttttgct tcgcaatttc agatgatgca aagacggatt cctgtccgca atctgctcat
     5641 tatcctagca gttgttgcgg tgtccttctt tttgctcttg acagtggtgt ctcagtcact
     5701 agctgttctg tttgcgacgc tacttggttg tagcatgggg gtggttttag atggtcagta
     5761 agtatctttt attagcagtt attttctctg gcttggtgac ttggattctc cgtatgattc
     5821 ccttcatctt agtcaagtat aagggcttgc ctgcaatcgt tgagcgtttt ttgaagttct
     5881 tgcccgtttc cattatcttt gccttgattc tttcaagcgt agtgacaggt aaggttggga
     5941 gccttcctca aattaaatgg ctagacttct tagccgtctt tccaacagct tgggtagcct
     6001 ttcgctaccg caatctagtc ggaacagttc tctttggagt ggtcttgatt gccatcttgc
     6061 gtttggtctt ttaaattacc cataaaaaaa acttatcaca gagatagata tcatataatg
     6121 gcgtaaatgc tctttttctg ttaagattat aaggtattct attttggagg aaatgacatg
     6181 aaaaaaatcg ttaaatactc atctcttgct gccctaggac ttgttgctgc aggtgtgctt
     6241 gcggcttgct cagggggtgc taagaaagaa ggagaagcag ctagcaagaa agaaatcatc
     6301 gttgcaacca atggatcacc aaggccattt atctatgaag aaaatggcga attgactggt
     6361 tacgagattg aagtcgttcg cgctatcttt aaagattctg acaaatatga tgtcaagttt
     6421 gaaaagacag aatggtcagg tgtctttgct ggtcttgacg ctgaccgtta caatatggct
     6481 gtcaacaatc ttagctacac taaagaacgt gcggagaaat acctctatgc cgcaccaatt
     6541 gcccaaaatc ctaatgtcct tgtcgtgaag aaagatgact ctagtatcaa gtctctcgat
     6601 gatatcggtg gaaaatcgac ggaagtcgtt caagccacta catcagctaa gcagttagaa
     6661 gcatacaatg ctgaacacac ggacaaccca actatcctta actatactaa ggcagacttc
     6721 caacaaatca tggtacgttt gagcgatgga caatttgact ataagatttt tgataaaatc
     6781 ggtgttgaaa cagtgatcaa gaaccaaggt ttggacaact tgaaagttat cgaacttcca
     6841 agcgaccaac aaccgtacgt ttacccactt cttgctcagg gtcaagatga gttgaaatcg
     6901 tttgtagaca aacgcatcaa agaactttat aaagatggaa ctcttgaaaa attgtctaaa
     6961 caattcttcg gagacactta tctaccggca gaagctgata ttaaataatt tcttgaaatc
     7021 atccattctg agtaaggtgg gtggtttctc agtttttagg gatatagttt taaactatat
     7081 atctgactat ctaataacaa tttgtgaaat caaacaaatt gtgagatact agtacggtat
     7141 tatttttaag gagaaagaat catgaaaatc aaaaaatggc ttggtctagc agcccttgct
     7201 acagtcgcag gtttggctct tgcagcttgc ggaaactcag aaaagaaagc agacaatgca
     7261 acaactatca aaatcgcaac tgttaaccgt agcggttctg aagaaaaacg ttgggacaaa
     7321 atccaagaat tggttaaaaa agacggaatt accttggaat ttacagagtt cacagactac
     7381 tcacaaccaa acaaagcaac tgctgatggc gaagtagatt tgaacgcttt ccaacactat
     7441 aacttcttga acaactggaa caaagaaaac ggaaaagacc ttgtagcgat tgcagatact
     7501 tacatctctc caatccgcct ttactcaggt ttgaatggaa gtgccaacaa gtacactaaa
     7561 gtagaagaca tcccagcaaa cggagaaatc gctgtaccga atgacgctac aaatgaaagc
     7621 cgtgcgcttt acttgcttca atcagctggc ttgattaaat tggatgtttc tggaactgct
     7681 cttgcaacag ttgccaacat caaagaaaat ccaaagaatt tgaaaatcac tgaattggac
     7741 gctagccaaa cagctcgttc attgtcatca gttgacgctg ccgttgtaaa caataccttc
     7801 gttacagaag caaaattgga ctacaagaaa gcacttttca aagaacaagc tgatgaaaac
     7861 tcaaaacaat ggtacaacat cattgttgca aaaaaagatt gggaaacatc acctaaggct
     7921 gatgctatca agaaagtaat cgcagcttac cacacagatg acgtgaaaaa agttatcgaa
     7981 gaatcatcag atggtttgga tcaaccagtt tggtaataag aaacagggag gtgggagaga
     8041 aaattccacc tcttgctttt gtatagagta tagattgtaa agaagactat tcgttcatag
     8101 aaaggtagag agaatatggt ttttcctagc gaacaagaac agattgaaaa atttgaaaag
     8161 gatcatgtag tccaacatta ttttgaggtt ttgcgtacct tgatttctaa gaaatcagtc
     8221 tttgcccagc aggttggact caaggaagtc gcaaattatc tgggtgagat tttcaagcgt
     8281 gttggagctg aagtggagat tgatgagagc tatacagcgc cctttgtcat ggcacatttc
     8341 aagagttcgc gtccagatgc caagaccttg attttctata accactatga cactgtgcca
     8401 gcggatgggg atcaggtctg gacagaggat ccttttacgc tttcggtccg caatggcttc
     8461 atgtatgggc gtggggttga tgacgacaag ggtcatatca cagctcgctt gagtgctttg
     8521 agaaaatata tgcagcacca tgatgattta cctgtcaata tcagctttat catggaggga
     8581 gcggaggaat cggcttcaac agacctagat aagtatttgg aaaagcatgc agacaaactc
     8641 cgtggggcgg atttgttggt ctgggaacaa gggaccaaaa atgccttgga acagctggaa
     8701 atttctggtg gcaataaggg gattgtgacc tttgatgcca aggtaaaaag cgctgatgtg
     8761 gatatccact cgagttatgg tggtgttgtg gaatcagctc cttggtatct cctccaagcc
     8821 ttacagtctc ttcgtgctgc ggatggccgt atcttggttg aaggcttgta cgaagaagta
     8881 caagagctca atgaacgaga aatggccttg ctagaaactt atggtcaacg aaacccagag
     8941 gaagttagtc ggatttatgg attggagttg cctctcttac aggaggagcg gatggccttt
     9001 ctaaaacgtt tctttttcga gccagcgctt aatatcgaag gaatccagtc tggttatcaa
     9061 ggtcagggtg ttaagactat tttacctgca gaagccagtg ccaagctaga ggttcgtctg
     9121 gttccgggcc tagaaccgca tgatgttctg gaaaaaattc ggaaacaact agacaaaaat
     9181 ggctttgata aggtagaatt atactatacc ttgggagaga tgagctatcg aagcgatatg
     9241 agcgcaccag ccattctcaa tgtgatcgag ttggccaaga aattctatcc acagggcgtt
     9301 tcagtcttgc cgacgacagc ggggacagga cctatgcata cggtctttga tgccctagag
     9361 gtaccaatgg ttgcattcgg tctaggaaat gccaatagcc gagaccacgg tggagatgaa
     9421 aatgtgcgaa tcgctgatta ttacacccat atcgaattag tagaggagct gattagaagc
     9481 tatgagtaga gatattatca agttagatca gatcgatgtg acttttcacc aaaagaagag
     9541 aaccattaca gcggttaagg atgtgaccat tcacatccaa gaaggggata tctacggaat
     9601 cgttggatat tctggagcag ggaaatcaac ccttgtacgg gtgattaacc tcttgcaaaa
     9661 accatctgca gggaaaatta ccattgacga cgatgtgatt tttgatggta aggtcacctt
     9721 gacggcagag cagttgcgtc gtaaacgtca agatatcggg atgattttcc agcattttaa
     9781 cctgatgagc caaaagacag cagaggagaa tgtagccttt gcccttaaac actctggact
     9841 cagcaaggaa gaaaagaagg ctaaagtagc taagttgttg gacttggttg gtttggcaga
     9901 tcgtgctgaa aactaccctt cacaactatc tggagggcaa aaacagcgtg tggcaattgc
     9961 gcgtgccttg gccaatgatc caaaaatctt gatttcagac gagtcaactt ctgcccttga
    10021 ccctaagaca accaagcaga ttttggcctt gttgcaagat ttgaaccaaa aattaggctt
    10081 gactgttgtc ttgattacgc atgaaatgca gattgtcaaa gacattgcca accgtgttgc
    10141 agttatgcag gatgggcatt tgattgaaga gggtagtgtg cttgaaatct tctcaaaccc
    10201 taaacaacct ttgactcaag actttatctc aacagctaca ggtattgacg aagccatggt
    10261 caaaatcgag aagcaagaaa tcgtggaaca cttgtctgaa aacagtctct tggtgcaact
    10321 caagtacgct ggagcttcaa cagacgagcc acttttgaat gaattgtaca agcattacca
    10381 agtaatggct aatattctct atgggaatat cgaaattctc gatggtactc ctgttggaga
    10441 attggtggtg gttttgtcag gtgaaaaagc agcgttggca ggtgcccaag aagccattcg
    10501 tcaagcaggt gtacaactaa aagtattgaa gggagtacag taagatggaa tcattgattc
    10561 aaacctattt accaaatgtc tataagatgg gttgggctgg tcaggcaggc tggggaacgg
    10621 ctatctactt aactctttat atgacagttc tttccttcat tatcggaggc ttcttggggc
    10681 tagtggcagg tctctttctc gtcttgacag cgccaggtgg tgtcttggag aataaagtcg
    10741 tattctggat tttagacaaa attacctcaa tttttcgtgc ggttcccttt atcatcctct
    10801 tggcaatctt gtcaccactt tctcacttga ttgttaaaac aagtatcggg ccaaatgcag
    10861 cccttgtccc actttctttt gcagtctttg ccttctttgc ccgtcaggtg caggttgtct
    10921 tggctgaatt ggatggcggt gtcattgagg cggctcaagc gagcggagcg actttctggg
    10981 acatcgtggg tgtttaccta tcagaaggtc ttccagattt gatccgtgtg acgactgtga
    11041 ccttgatttc ccttgttggg gaaacagcta tggccggtgc ggttggagct ggtggtatcg
    11101 gtaacgtagc catcgcttat ggatttaacc gctacaatca cgatgtgacc atcttggcaa
    11161 ccatcattat cattttgatt atctttgcaa tccaattctt gggagatttc tcgactaaga
    11221 aattgagcca taaataaaaa agagccgcgt ggctcttttt aactgatcag attttctgtg
    11281 caaatttttt actcaaggct tgtccaatca aggcacccac tagggctccg atgacaatac
    11341 ttgcgataaa tagaaggaca gttccagggt ttggagcgac catgatgcgg tcgatatatt
    11401 cttgggattt tcctcttgcc agaagagtag ccatataggc tttgggcgca atccacataa
    11461 gcaagattgg tcctgttgta ctaaaggcga aaataatgaa agaaaggaag ttctttgttt
    11521 tgtccttgta ttttcctaaa tgagctactt catctgctag gaggccacag ataattccag
    11581 gaaggaagga accagcaccg tgtttagttc ccaagaaaaa gaaggcaatg acaaggccga
    11641 tagtggtaat ggctccaaag cgcggaactt ttgcgactag gatcatatag acgctaccgc
    11701 cgacaagggc agtaaaggca ggcgcataaa acatgtttcc agtttggtca aagagattgc
    11761 ccaaaaggac accaatcccc atgcagagga agtaaagaac tgcaaaaagc agtgtagtta
    11821 agatagattt cttcatgaat tgtctcctga taattttttc acaattctca ttttaccatg
    11881 gtttggtggg attgtaaatg gatactagaa gtttttgaaa acgcttgaaa tatgatataa
    11941 tggtttcata gttattttta ggggaatatc atgggtagat ttttagactt tgtctttaat
    12001 cgtttctttt tagggatgat tgcgacagcc ttcttttggc tattaacttt agcaggaggg
    12061 attatccttg gtctagcgcc ggctagtgcc accttgatga gcttatatgc agaacatggt
    12121 tatagctttc gggaatacag tttgaaggag gcttggtctc tttacaagca aaattttgtc
    12181 tcaagcaacc tgattttcta tagcttttta ggtgtgggtc tagttttgac ctatggtttg
    12241 tatctcttgg tgcaattgcc tcatcagacc attgttcatt tgattgcgac ccttttgaat
    12301 gtcctagtag ttgccctgat ctttttggct tatacagtat ctttaaaatt acaagtttat
    12361 tttgccttgt cctatcgaaa tagtctcaaa ttatccttga ttggcatctt tatgagtcta
    12421 gcagctgtgg ccaaggttct ccttgggact gtgctacttg tagcaattgg ttactatatg
    12481 cctgccctgc tattttttgt aggaattggg atgtggcatt tctttatcag tgatatgttg
    12541 gaacctgtct atgaaatcat ccatgaaaaa ttggcgacaa aatagaatga agcagttttg
    12601 gctacatacg cttctaagaa cctatagttc agtgatgatc attatcattg cgagttttgc
    12661 aatcttactc tcttacgctg actgggattc acgtgaaaag gaagcccaga gagtagccca
    12721 gcgtgtaact gctagaacag tgagtgaaat tgaatattac catagagagt caacccagat
    12781 agctcaggct ttagttgaaa atcaagctcg tattgaggga atctataaat actttagcct
    12841 tagcatgcca gactattttt actggcaatt agagcggaaa gcttcgcctt atatatcagt
    12901 ctctctgtat gaaaatgttg atgacctcta tgttcgaaat gattttgtaa ctggagtggc
    12961 cattgctttt caagattaca aggaagtcta tgtttctact aaagacaaac gtagtggaga
    13021 aaaaatcagg gctgaggatt tcaaaccagc aggaaatagt tttgccattc cggtgtcaga
    13081 tccagtgtca gatcaagatt taggagtgat ttacatctcc ttggattctg ctgttttata
    13141 ccatgccatt gataatacta gaggtcatac tccgatggca gtaacagtga cctcaccttt
    13201 tgatacggag atttttcata ttggtgagac agttgataag gagagtgaaa attggctagt
    13261 tggcttaact tctcatggat atcaggttca ggtggcagtt cctaaaaact ttgttttaca
    13321 aggaacagtg actagctctg ctttgattgt gggtttgagc cttctcttta ttgtcattct
    13381 ttatctgact ttgaggcaga cttttgctaa ttaccaaaag caggtagtgg atttagtaga
    13441 atccattcaa gtcattgctc aaggcgaaga ggggcgtcgg attgacattt ccgaaaaaga
    13501 tcaggaatta ctcctaatcg cggagacgac caatgatatg ttggatcgat tggaaaagaa
    13561 tatccatgat atttaccagt tagagcttag tcaaaaagat gccaatatgc gagccttgca
    13621 ggcgcaaatc aatcctcatt ttatgtataa tacgctggag ttcttgcgca tgtatgcagt
    13681 tatgcagagt caagatgagt tggcagatat catttatgaa ttcagtagtc tcttgcgtaa
    13741 caatatttcc gacgaaagag agaccctcct caaacaggaa ttagaatttt gccgtaaata
    13801 cagctatctc tgcatggttc gctatcccaa gtccattgcc tatggtttca agatagatcc
    13861 agagttagag aatatgaaga ttcccaagtt taccttgcaa ccgctggtag aaaactattt
    13921 cgcgcatggt gttgaccaca ggaggacaga taatgtgatt agcatcaagg ctcttaaaca
    13981 ggatgggttt gtggaaattt tggtggtcga taatggtaga ggaatgtcgg ctgaaaagtt
    14041 ggcaaatatc cgagaaaaat taagtcagag atattttgaa caccaagcca gctacagtga
    14101 tcaaaggcag tctatcggga ttgtcaatgt acacgagcgt tttgtgctct attttggaga
    14161 ccgctatgcc attacgatag agtctgcaga gcaagccggt gttcagtatc gtattacaat
    14221 tcaagatgag tagaaaggga gaaaatgtat aaagtattat tagtagatga tgagtacatg
    14281 gtgacagaag gtctgaagcg tttgattccc tttgataagt gggatatgga ggtcgtcgca
    14341 acagccagtc atgccgatga agctctagaa tatgttcagg aaaatcctgt cgatgtcatc
    14401 atttccgatg tcaatatgcc agacaaaaca gggcttgata tgattcggga gatgaaagag
    14461 atcttaccag atgctgccta tatcctgctc tcaggttatc aggagtttga ttatgtaaaa
    14521 agagcaatga accttagtgt ggtggactat ttggtcaagc ctgttgataa ggtagagctg
    14581 ggaaatctgc tggagaagat tgcaggtcag ctcggcgaga gagggaagaa aagtcagact
    14641 cttagtcaag aattagacga ggctggattt gttagttatt taggggataa ggagaattgg
    14701 tggataggtc tatccaagga aaaacaaggt tccttcacca ttccctacta tgtcttgggt
    14761 caagactggc agattttcat ttctggccac cccctagatg gtttagtcgt tacacctttt
    14821 gaagctcctt atcaagaaca ctttgaacgc tggaagctga atgctgagaa aaccctcttt
    14881 tacggttctg taaatctgca gcagtctgag agtctctttg cctattacga accgatttat
    14941 agggttatca ttcagggaaa tctcaatcaa atcgtagaag agttaaatct cttggagaag
    15001 gtagttcttg aaaatacacc tcgtgtttcg attactaaac agctttttat ccagtttgtc
    15061 atggatgttt tccatttatt tgaacatctc aaagctgatg atatgacgga cattgtcaaa
    15121 accattcatg ctattcaatc cttcgatgaa ttggtttctt atatcaagga aactctgatc
    15181 agctttttcg gtcaataccg tatgaatgaa aatgtggtca gtgtgctgga agtcattggt
    15241 cgtgattacc aaaaagagct ttccctcaag gatatcagta aggccctctt tatcaatcct
    15301 gtctatctag ggcagttgat taagcgtgaa accgattcga cctttgcaga gttactaaac
    15361 aaacaacgta ttaaggctgc ccagcagctc ttgctttcaa ccagtgacag tatcgaagat
    15421 atttgttatg ctgttggtta cagtaacctt ggatatttct ataaagtttt ccgaaaattg
    15481 tgcggaaaat cgccaaaagc ctaccgaaaa caggtagaaa ctatactata agatttgtat
    15541 tcctttacaa aaggtgctat aatattatca ggaggtccta tcatgaaaaa gaaaccaatt
    15601 tatctatggg ttttgctaat cttgtctgcc cttatttcag ttccgtctct gtttggaatt
    15661 gtgagtccct tgcctagtaa agaagccctt cgtgctgctc agaaacaagt tgcaggggtc
    15721 aatgctcagc aattagaaga ccagcttaat tatacctata gagtagcaga agcatctcat
    15781 tctattttta atgttgcttt gattgtgcta tctactattt tagtggtcgt agcgattgtc
    15841 ttccttgttc gtaaaaattt gcaatatgca aactatactt acgttggcta tgttttgtta
    15901 gctattattg gttcgattta tggctatgtt ggtttacaag acgctgtgca gttggttcaa
    15961 gatgagagca tgcgtttgac agtgagtatt ggttcaaaag ctgttagcat tttctatatc
    16021 gtcatcaatg ttctcttcct agcgcttgtc ttctataaga tgtggcgaca acagaaagcc
    16081 ttggcagaag aagaggaaac agaagagctt gcctaagtat tgacaaaaaa gaactatcaa
    16141 gatacaatct tggtagttgt tttttgatta tagataaaat catggaggta catatgaaga
    16201 caatttcttt agtttatatt agtttgagtg gcaacactga aagttttgtg acgcgcttga
    16261 aagactatct cttgtcccag tacaaaggga ttgaggttca aaagattcat atcaaggatt
    16321 tggtcaagga aggcaaaaat ttctatgaaa tggaccatcc ctatgtcgct tttttgccga
    16381 cctatctcga aggtgggaat ggcgtggata acggagatgt tgagattttg acgacaccgg
    16441 tgggagattt tattgcctat ggtaacaatg ctagtaagtg ttttggtgtg gttgggtcag
    16501 gaaatcgtaa ctttaataac caatactgcc taacagccaa gcaatacagt caacgctttg
    16561 gcttccctgt attggctgac tttgaaatgc gaggcatgct ggaagatatc aaacatgtcg
    16621 cagctattat cgcagatttg tatgagttgg aaaaggagaa ttaatactca atgaaaatca
    16681 aagagcaaac taggaagcta gtcgcaggtt gctcaaagca cagctttgag gttgcagata
    16741 gagctgacgt ggtttgaaga gattctcgaa tagtataaag ttcttataag aggtggttga
    16801 agttgttcaa ctgttttttg agtataaaca gtctttaaga acgtaaaaaa gcataagttc
    16861 aggtcttcaa aaccttgttc ttatgctttt tatcatagaa atatttgctg aattttctct
    16921 tgaaatgaaa ccttatcttc atctcgcgct tgtcccttac cctgcttttc cgattgcgag
    16981 tgcgtagata aagaagatgg cgaagccaaa gaggaaaatc aatcccgcaa tggcaaggtg
    17041 tttgagccaa gaaggaagat ttttgttttc acgcgttacc aaggcgtaat tcaaaagagc
    17101 aaagaaaggt gttgtcagga aagatccaat catggcaaag cggagcatgg ttgaaacctg
    17161 accagcgaag aacttgataa tgacgatacc gatgatagca gtgatggtca tccagatgtt
    17221 caaagattta cgattgtcct ctttttgact gattagcagt cggagagatt cctgattaac
    17281 gcgagaatag ccatcgataa cagttataac tgttccaaag atacagagga aggcaataaa
    17341 ggtaatcaag taacgggacc attcgccaag aacagaggca tacatgccca cgaattgaga
    17401 gatgtatttg gctgaagcag cttcaaccgc ctgccctgta ggatactgaa tcagtgctcc
    17461 cagtgccaca aagaagacgg ctaggatagc tgttccaata taaccagtgt taaagtcaaa
    17521 cagagcgtct tctgtgttaa agttgacggt ctttctcttt tcagctgacc aaagtgaatt
    17581 gatggctgaa atttcaatag gagccggcat ccatcctagg agggagacga tgaagggcag
    17641 agctgccatt tgccaaggtg tcttctcgac aaaatcagaa ctgtattctg gatgcttgac
    17701 cgccgcaatg ataactgcca gaacagtcgc aatggttaag gcagacataa tccatttgac
    17761 catgccgtct aaaagtttgt agcctccaaa gagtagcata gcccaaatga ttgcaacgag
    17821 aatgagggac cactgagtaa tgctaagtcc aatcattggg aaggcactgg cgatgatagc
    17881 tgagcacaga atggcaacac cagccgtgtt gaccatagcc gaaaagacat tgaggataaa
    17941 gaaaatccag agatagagtt ttcctttttc ggcataacct tcaaccaaag tctttccagt
    18001 atcagctgtg tattcagcac caaaacggaa aaatggatat ttaaagacat tggctaagat
    18061 gaccaagaga agtagagacc aaccgtaaga accgccagct tgagttgagg atacaatgtg
    18121 ggaacctcca acagcggcag ttgccattag gattccaggt cccattgctt ttagcttgct
    18181 tgcccaggtt gattgattta aggaaatagc ttgcgacatg ataaatactc ctttttgaat
    18241 tttcagaata atctgtatat gtaatctata ttctacaaaa aattttggaa aaatgcaaga
    18301 gtattttgaa aaaagataga aaatttacaa agaaaatctg aaataactgt tatgatatag
    18361 cagattgaaa ctagaatagt acacctttgc ttctaaaaca ttgttagaaa tcgatttgac
    18421 tgtcctgatc gatttatcct gttcttattt catttcacta tagtaaggtg cagcaggata
    18481 aagaaaaacc gagaagtttc tttctcggat ttgcttatta tgaggttcct attttctatg
    18541 ctccaagagt tgattgatgt gatctacttt tttagcctct cttttataga gaatagccca
    18601 gattatgaga tagacaatcg caaactcgat aatgagctgg aggtagaaaa tccagtggaa
    18661 agggaaccaa ccagcaagag ttgctagtgg gacaaagcca gccagcataa ggaagaaatg
    18721 agtcagagtg gcacgaagca tgctccagtc acggctgaat aagcggttgc caaagttgaa
    18781 gagcataccg atggctgccc agataagtgt gcagtagagc aagaccaggg caccgtgaac
    18841 ctgctgctga tccatcactt ggccgatgag agagtaggga tttagtggtg cgtaggtatt
    18901 tggtgcataa atgagtgaaa agaggatgga gaggatgagg ccgataagaa caccggcagc
    18961 tgcatcgtga aatacttgtt ttttcatagt tctaatttct ccttgatggt ttttagataa
    19021 cggcgtgaag agtaggtgaa gctttcgttt ttcaagaaaa tttctaccag accgtttggc
    19081 gtgagcttga ggtgagagat ggaatcgata ttgatgattt ctgattggga aatttggata
    19141 aaattggttg gcaagagttt aagaacctga tagagtcgca aatcaatgct gtaggtctga
    19201 ctcgcggttt ctgctagaac cttccgattc tcgatataga agcgctgaat cttgccaatc
    19261 tcaactagat agacctgatc atagattttc cctttgattt tttctctttg gtccagattt
    19321 tctgcgaact cgatgacttt ctggactttt tcggtttctt gaggtgcttg gacaatcagc
    19381 ttttcctcct cgtaagtctc actaatctgt agttctactt tcataaattt ctctccttgt
    19441 ttttcataca aaattaatct cacttcttgt acacctttat taatactctt caaaaatctc
    19501 ttcaaaccac gtcagcgtcg tctcgccgta ggatagttgt tgactttgtc agttttatct
    19561 acaacctcaa aacagtgttt tgaactgtct gcgcctagct ttctagtttg ctctttgatt
    19621 tttattgagt ataccactat tttactccct ctggcaaggg actttgtcta tgtagaggga
    19681 ttgggctcct atgtggtgga gcttttctgt tctttctgaa atatggtata atagcactaa
    19741 ttaatttcta ggaaaataga tacagaaagg ggctgaaaga tgtctcatat tattgaattg
    19801 ccagagatgc tggcaaacca aatcgcagct ggagaggtca ttgaacgtcc tgccagtgtg
    19861 gtcaaagagt tggtagaaaa tgccattgac gcgggctcta gtcagattat cattgagatt
    19921 gaggaagctg gtctcaagaa ggttcaaatc acggataacg gtcatggaat tgcccacgat
    19981 gaggtggagt tggccctgcg tcgccatgcg accagtaaga taaaaaatca agcagatctc
    20041 tttcggattc ggacgcttgg ttttcgtggt gaagccttgc cttctattgc gtctgttagt
    20101 gtcttgactc tgttaacggc ggtggatggt gctagtcatg gaaccaagtt agtcgcgcgt
    20161 gggggtgaag ttgaggaagt catcccagcg actagtcctg tgggaaccaa ggtttgtgtg
    20221 gaggatctct ttttcaacac gcctgcccgt ctcaagtata tgaagagcca gcaagcggag
    20281 ttgtctcata tcattgatat tgtcaaccgt ctgggcttgg cccatcctga gatttctttt
    20341 agcttgatta gtgatggcaa ggaaatgacg cggacagcag ggactggtca actgcgccaa
    20401 gcaatcgcag ggatttacgg tttggtcagt gccaagaaga tgattgaaat tgagaactct
    20461 gacctagatt tcgaaatttc aggttttgtg tctttacctg agttgactcg ggctaaccgc
    20521 aattatatca gcctcttcat caatggccgt tatatcaaga acttcctgct caatcgtgct
    20581 attttggatg gtttcggaag caagcttatg gttggacgtt ttccactggc tgtcattcac
    20641 atccatatcg acccttatct agcggatgtc aatgtgcatc caactaagca agaggtgcgg
    20701 atttccaagg aaaaagaact gatgaccctg gtttcagaag ctattgcaaa tagtctcaag
    20761 gaacaaacct tgattccaga tgccttggaa aatcttgcca aatcgaccgt gcgcaatcgt
    20821 gagaaggtgg agcaaactat tctcccactc aaagaaaata cgctctacta tgagaaaact
    20881 gagccgtcaa gacctagtca aactgaagta gctgattatc aggtagaatt gactgatgaa
    20941 gggcaggatt tgaccctgtt tgccaaggaa accttggacc gattgaccaa gccagcaaaa
    21001 ctgcattttg cagagagaaa gcctgctaac tacgaccagc tagaccatcc agagttagat
    21061 cttgctagca tcgataaggc ttatgacaaa ctggagcgag aagaagcatc cagcttccca
    21121 gagttggagt ttttcggaca aatgcacggg acttatctct ttgcccaagg gcgagatgga
    21181 ctttacatca tagatcagca cgctgctcag gaacgggtca agtacgagga gtaccgtgaa
    21241 agcattggca atgttgacca gagccagcag caactcctag tgccctatat ctttgaattt
    21301 cctgcggatg atgccctgcg tctcaaggaa agaatgcctc tcttagagga agtgggcgtc
    21361 tttctagcag agtacggaga aaatcaattt attctacgtg aacatcctat ttggatggca
    21421 gaagaagaga ttgaatcagg catctatgag atgtgcgaca tgctcctttt gaccaaggaa
    21481 gtttctatca agaaataccg agcagagctg gctatcatga tgtcttgtaa gcgatctatc
    21541 aaggccaatc atcgtattga tgatcattca gctagacaac tcctctatca gctttctcaa
    21601 tgtgacaatc cctataactg tcctcacgga cgtcctgttt tggtgcattt taccaagtcg
    21661 gatatggaaa agatgttccg acgtattcag gaaaatcaca ccagtctccg tgagttgggg
    21721 aaatattaaa agtataaaaa agtctgggaa aaattttcaa aatcagaaaa acgcataaaa
    21781 tcaggtgttc aaaaaccttg attttatgcg ttttatcata gaaatattta cttcattttt
    21841 tcctaattct tttcgaaact ctttttaaac cacgtcagtt ttatcagtaa tctcaaaaca
    21901 gtgttttgag ctaattttgc cagttttgtc tgtaacatcg aagttgtgtt ttaccactct
    21961 gcgactggtt tcctagtttg ctctatgatt ttcacagagt attaaattgc gattttgcca
    22021 agtttcttta ttcgtctaaa agtagagtct gttctatgcg tctaatgtac gaattaggtt
    22081 gaccatttca atagctcctt gtgcacactc agaaccctta tttcctgctt tagtaccagc
    22141 tcgttctatg gcttgttcaa ttgtatctgt cgttaacaca ccaaacataa caggaatttc
    22201 gctatttaaa ctgatttggg cgattccctt agatacctcg ctacatacat aatcataatg
    22261 acttgtattt cctctaatga cagctcccaa gcagataatt gcatcatatt ttttactttt
    22321 tgccattttt gatgcaatca gtggtatttc aaaagctcct ggaacccagg ctacctcgat
    22381 atctttctcg tttacattct ctcttttgag attatctagt gctccagata ataattttga
    22441 agttataaat tcattaaatc tcgctacaac aatacctatt ttaatattgt ttgctactaa
    22501 attaccttca taagtgttca tttatttttc ctccatattt aaaatgtgac ccattcgatt
    22561 tttctttgtt tctaaataaa aactatcgta aggattggct tctatttcga ttgatattct
    22621 actggaaatg gtaattccat atttttctaa ctgttcaacc ttgtcaggat tatttgtcag
    22681 taaatgaagt gactgaagtc ccagatcttt aagcatttgt gctccaatat gatattctct
    22741 taaatcacct tcaaagccta atgcaagatt ggcatcaagc gtatccatgc cttgatcttg
    22801 taaatgatag gcttttaatt tattgataag tccaattcct cgtccctcct gtcgcaagta
    22861 aagtaagaca cccgaaccat tctcaacaat cattttcata gctttatcga attgctgtcc
    22921 acaatcgcaa cgtaaagagc ctaaaacatc tcctgttaaa cattcggagt ggacccgaca
    22981 taatacattg gcttcatcct ctatgtttcc cataataaga gcaagatgat gttccccatt
    23041 tagtttatct atatagctaa ttgctttgaa attaccgtat ctagtaggca tattgacagt
    23101 tgaaactcgt tctaccagct gatcatatac ttttctatat tcttgtaatt ctttgatggt
    23161 aattagtgga atgttgtgtt tcttcgagaa ctgaattaaa tcatctgttc tcatcatttt
    23221 gccatcatga ttcattattt cacaacatag gccacactct tttagtccag ctaattttaa
    23281 taaatcaaca gttgcttctg tgtgtccatt tctttctaga acaccacctt tttttgcaat
    23341 taaaggaaac atgtgtcctg gcctgcgaaa atcagagggt gttatatctt cagctacaca
    23401 catacgtgcg gtcagtcctc tttcctcggc agaaatacct gtggtcgttt ctttataatc
    23461 aattgaaact gtaaaagcag tcttatgatt atctgtattg ttttcaacca taggtgaaag
    23521 cattaattga ttagctaaac tttcgctcat aggcatacaa attaatcctt tggcataagt
    23581 agccataaaa ttaacatttt ctgttgtagc tgcttgtgca gaacaaatta agtctccttc
    23641 attttctcta tccttgtcgt ctataacaag aacaagtcgt cccttctgca atgcttctaa
    23701 tgcttcttgt atttttcgat attccattga ctgattatcc tttctgctaa aatccatttt
    23761 gatataatag ttccttagat atttctgatt ttggagagtt atccatcagt ttttgcacat
    23821 atttacctaa gatatcattt tcaagattta ctgtactccc gacttgttta ctcttaagaa
    23881 tggtttgttc caaggtatga gggataacag atactgaaaa gtttactttg gagactttag
    23941 cgacagtcag actaatgccg tcaattgtaa tagatccttt ttcaactatt aaatctaaaa
    24001 tttctttttg tgtgttgatt tgataccata cagcattatc atcttttttt attgacgaga
    24061 tttttcctgt accatcaatg tgtcctgtaa cgacgtgacc cccaagtcga ccgttgacag
    24121 ataaggctct ttctagattc acctcacttc catgttttaa tagagtaaga gctgttcgac
    24181 tccatgtttc attcattaca tcaactgtaa aggattgatg attgaaatga gtaactgtaa
    24241 gacagatacc atttactgct atactatcgc ctaaatggat atccgttaat atttttgagg
    24301 ctttaattga tagtttacaa ttacgagagt ctttctgtat tctttcaact tttccgattt
    24361 cttcaattat tcctgtgaac atggataaat cacttcactt tctatgagat agtcatttcc
    24421 tatttgagaa aatgcataag gtttcaatct aatagcgtca tttggcaaag aaataccttc
    24481 acctccgaca ggaaacttgg cactacctcc aaaaattttt ggtgcaatat atattttcag
    24541 ctcatcaaca atttgttgtt ccaaagcact ccaattcatt agactgcccc cttctagaac
    24601 taggctatca atctgcatgt ttcctagatg ttgcattaaa ctcgataagt ctatatgatt
    24661 gccttttttc tttatggaaa gtatttcaca gccatgattt tgatatagct tcattttatt
    24721 tttgtcttca gaggaagtgg caatgtaagt tttaatatca tttgctgttt ttacgatttt
    24781 agaggtaaga ggagttcgta aatgtgtatc gcatatgata cggataggat ttttcccttc
    24841 ctccaatcta catgtcagca aaggatcgtc ttgaataaca gtattgactc ccaccataat
    24901 tgcactaaca tggtgtcgta actgatgcac atgctttctt gcttcttctt cagtaatcca
    24961 tttggattga tttgttttag tggctatttt tccatccatt gacattgcat atttcataaa
    25021 aacatagggt acatgctggg taatatactt tctaaaactt tttattaagt taagacactc
    25081 attttctaaa attccaacag taacttgaag attattttcc tcaagtatct ttactccttt
    25141 tccagataca ataggattac agtctaggct tccaatgact actcttgtaa taccactatc
    25201 gattatagca tctatacagg gaggtgtttt cccgaagtga caacagggtt caagtgttac
    25261 ataaagcgtc gctccgacag gggattctct acagttttta agagcatttc tctcagcatg
    25321 tgggccacca aaaaactcat gataaccttg tccgataatg tgattatctt ttacaataac
    25381 tgcgccgacc ataggattgg gattgacgta accagcccct ttttgtgcca gttttattgc
    25441 taatttcata tattttgaat cgctcatctc actacctcca aaaaaatatg ccttgaatag
    25501 gggactactc aaggcataca aaagaaaact tatgcgatta acaaaaatgc tctgaaatga
    25561 caagtaatca tttcagagca cgcaaaaagc acaaatatac ttttatcttc tttcatccag
    25621 actatactgt cggctttgga atttcaccaa atcatgcctt tcggctcgtg ggctatacca
    25681 ccggtaggga atttcaccct gccctgaaga tagttattca attacagatg attatagtac
    25741 ttaattttga atatgtcaac agataaatac cgattgtttt tgatatactg tatttgtgat
    25801 aatcgattct cgctcctcgg ataaagaaaa tatgatatac tagataaacg aaataagaga
    25861 gaaggaatac tatgtacgca tatttaaaag gaatcattac caaaattact gccaaataca
    25921 ttgttcttga aaccaatggt attggttata tcctgcatgt ggccaatcct tatgcctatt
    25981 caggtcaggt taatcaggag gctcagattt atgtgcatca ggttgtgcgt gaggacgccc
    26041 atttgcttta tggatttcgc tcagaggatg agaaaaagct ctttcttagt ctgatttcgg
    26101 tctctgggat tggtcctgta tcagctcttg ctattatcgc tgctgatgac aatgctggct
    26161 tggttcaagc cattgaaacc aagaacatca cctacttgac caagttccct aaaattggca
    26221 agaaaacagc ccagcagatg gtgctggact tggaaggcaa ggtagtagtt gcaggagatg
    26281 gccttcctgc caaggtcgca gtgcaagcaa gtgctgaaaa ccaagaattg gaagaagcta
    26341 tggaagccat gttggctctg ggctacaagg caacagagct caagaaaatc aagaaattct
    26401 ttgaaggaac gacagataca gctgagaact atatcaagtc ggcccttaaa atgttggtca
    26461 aataggagca gagaatgaca aaacgttgtt cgtgggtcaa gatgaccaac ccactctaca
    26521 tcgcctatca tgatgaggag tgggcccagc ccctccatga tgaccaagcg ttgtttgagt
    26581 tgttgtgtat ggaaacctat caggcaggcc tgtcttggga aacggtactc aacaaacgcc
    26641 aagctttccg agaagccttt catagctatc aaattcactc agtcgcagag atgactgaca
    26701 ctgaattgga agccatgctg gagaatccag ctatcattcg aaatagagcc aagatttttg
    26761 ctacacgcgc taacgcccaa gcctttctac agttacaggc agagtacggc tcttttgatg
    26821 cctatctttg gtcttttgtt gaggggaaaa ctgtcgttaa cgatgttcct gattatcgcc
    26881 aagccccagc taaaacaccc ttatctgaga aattagccaa agatctcaaa aaacgaggct
    26941 tcaagttcac aggcccagtc gccgtattgt cttttctaca ggctgcaggg ctagttgatg
    27001 accacgagaa tgattgtgag tggaaaggtc ttaaatgatg tctaacaaaa ataagggaat
    27061 tctgattttt gcgattctct atacagtcct ctttgtgttt gatggcgtta aattgctggc
    27121 ttctttaatg ccatctgcca ttgcaaatta tcttgtttat gtagttttag ctttatatgg
    27181 ctccttcttg ttcaaggata gattgatcca acaatggaag gagattagaa agactaaaag
    27241 aaaattcttc tttggagtct taacaggatg gctctttctc attctgatga ctgttgtctt
    27301 tgaatttgta tcagagatgt tgaagcagtt tgtgggacta gatggacaag gtctaaatca
    27361 gtctaatatt caaagtacct ttcaagaaca accactactg atagctgttt ttgcttgtgt
    27421 cattggacct ctggtagaag aattattttt ccgtcaggtc ttattgcatt acttgcagga
    27481 acggttgcca ggtttactaa gcattattct ggtaggactt gtttttgctc tgactcatat
    27541 gcacagtttg gctctatcag agtggattgg tgcagttggt tacttaggtg gaggccttgc
    27601 cttttctatt atttatgtga aagaaaaaga gaatatctac tatcccctac ttgttcacat
    27661 gttaagcaac agcctctcct taatcatttt agctatcagt atagtaaaat gaaatgagaa
    27721 caggacaaat cgatttctaa caatgtttta gaagtagagg tgtactattc tagtttcaat
    27781 atactgtaat atgtgatgaa aatgccagta atgataccga gaaaaaagct gagaaacttt
    27841 tcccagcttt atttgttata gtcaaagaga atgacttgtt cctgtgcatc tacatgagca
    27901 tggaccccaa agggtacaat tgctcttgga gttgcgtggc cgacattcag attatagaca
    27961 atcgggatat tgctgtcaat gatatccaat agtgcctctt tatagtcgtc atggaaagtt
    28021 tcatccatag gttttccgac caagagtcca ttgatgaccg cgaatatgcc agtgtccttt
    28081 aaagttagca acatcttttt gaagtcttct ggcttaggct tttcttcgct tgtttcgagc
    28141 aagaggattt tcccttccca gtctgacaag tcagggaaaa gtttgtattt ttggcagagt
    28201 tccgtgctat ctgcgtatcg agagttgtca aagatatcgt agagggattc gaggcaacca
    28261 ccgaggattt tcccctcgaa ctgggcactt ccttgcaaca agtcaaaacc tgtatttgta
    28321 tgactgacac gaggtgttcc cagggccgtg ggactaaaat cagttcgttc ctcataccaa
    28381 acgtcactag ggcggatttc tgaaattctt cccgtctcaa tcaattcttt aaagtagtga
    28441 aggctatagg ctagcatttc tttgtctaat tcacaaatgt ctgctaaaaa ggattgacca
    28501 taaaaagtct tgattcctaa tttatgcaac atgaggtggt tcatggttgt atccgagaag
    28561 ccaagaaaaa ttttttgttt gataaccttt tggagttggt cattttcaaa aagataaggt
    28621 agcaagcgat aggtatcgtc tctaccgatg gcacatagga tcatgtcgat gctatcatca
    28681 gaaaaggcat gaatcaaatc ctctgcacga gcttcaggat ggtccttgat aaagtctaat
    28741 ccttttaacg aatggggcaa aaagatggga ttgagtccca gatccttgag acgttggata
    28801 cccaagtcca cttcgtgttt gacaaaatcc tctccgataa tgccactaga taaactaaca
    28861 ataccaatag tagaaaccat atctcatcct cctagaaata gattgagcct attttatcac
    28921 aaaatataag agaaagctat gtgggatttc agaagaatac ttttaatact cttcgaaaat
    28981 ctcttcaaac cacgtcagtt ttatctgcaa cctcaaagct gtgctttgag caacctgcag
    29041 ctagcttcct agtttgctct ttgattttca ttgaatataa ctcaaaaaag taagtgaaaa
    29101 agcaaccgca cctgcagttg cttttatcgt tttcttattc ttgatagcgt gttggtcctg
    29161 cacttgcact acggatattc aagcgtttct tgagatagaa gcgaagggct aggagggcta
    29221 ctccaataat agctagtggc aatggatcca gtactgggtt aaggctagct ggtaggaagc
    29281 ttgttgcaaa gaagacaagc aaccaaagga acatagaagc taggataact agtacagatt
    29341 tccagaaagg tggacgttga ctgcgatcca tatctggtcc atagtattgg taaacaaagt
    29401 agtacatcaa gtagaaggca aatccaccaa ccagtccaac taatagaaga gtaatcaatc
    29461 catagccgaa agcttgatct gccgcaaaga aggttgtgag ggcgctgaca agggcaaaga
    29521 ggctagtgat gaaaagagct gagtccataa tcatcagttt tgggtcatca ttttcttttg
    29581 gatgctcttt ttcgtactgc tctttgacag tgaagctatg agcccaatga gttggtgcgc
    29641 cgtataggga acgggcagtt gtacctttag attgctcctc aaggatttgg ggaatgactt
    29701 cctcaaaaat agtctggatt tcagcgtctg ttttcccatc tttgatgaat tgttgggtag
    29761 caatgtggac aaactcttgg tttttcttag ttaatttttg tagatcaatt tgagacatag
    29821 gaactcctct tagaaccatt ttttatggat gagatagaga gtgagcgaga cactcatagc
    29881 aaaggcgata aagacgatta accagaaggc atttggctct ccgtttaggg gaatttcatt
    29941 atccttaaag ttcatcccgt aggcagaaaa gaccatggtt gggatggaca tgacgatggt
    30001 cacaagggcc aaggttttca tgatgttgtt ctggttgtta gaaatgatag aggcaaaggt
    30061 ctctgtcata gaatgcaaga cgtttccata aatatctgcc atctcgatgg cctgttgggt
    30121 ttcaatcagg gtgtcttcaa gcaggtcttc gtcctcaagg tatttcttga tattgctggt
    30181 tgaactggtc aatttcttaa tcacgcgctc atttgttttg agggaggcct tgaaatagac
    30241 gatagttttt tccaattcca tgagctcaat caattcttca ttacgagttg attgatgcag
    30301 ttgactttcg atttgttcac tcttgcggtc gattgaacga agggctgtta ggtaaagctc
    30361 tgcattgcga taaagaattt gaaagataaa acgtgaacgc atgaaggtat agaaattacg
    30421 caatcgacgg ttgataaaga catcaaggac aggtagtggt tccaaacacg tagtgataat
    30481 ggtttcctca gtgatgataa taccaagcgg gatggttacg tagtaggtgc ggttatttct
    30541 ttcctccgtg accggcacgt ctacgataat cagggtatac tcgtcttcaa tggtaatacg
    30601 agacatttct tccgcatcga gcggtgctcg aaggtcggca atatcaatat cgaaggtgtt
    30661 ggcgatttcg agtgattcat tttgagtcgg attgacgaga ttgatccaag tacccggttc
    30721 aagcgtatcg atctctttaa attcagttgt tgtagagaga aaaacttgtt tcatatccct
    30781 tatcctttct catttttcag attttttcac actgtactat tatactacaa aatcggcttt
    30841 tttcaaataa aatcttacaa agacaccgtt gttattggat ttttactttg tcttgaaatg
    30901 ttgattttta aatttgctcc cctttttgct ccccctatag tgcttttagt gcagtttcgt
    30961 agaatgatac tgcttttttt gcgttctctt ttgagaggtg actatatata tccatggtca
    31021 ttgataaagt ggaatgacct aggcggtact ggagttcctt gtatggtatt ccagagttaa
    31081 gcaagagact agcgtgagtg tgacggaatc cgtgaaatcc aatgttagga acatcagcac
    31141 gcttaaaatg tgtttgcaat cttcttttaa gtcttgaact gctaggatac tcatgaatga
    31201 aatcagaaaa taccacgcgt tcacgttgcc ctatcttcca ggcctcttta gtttggcgta
    31261 gtttgtactg cttcagcatg ctaacagtcg cttgatctat atctatatcc cgataactag
    31321 ccttagactt tgggctattg atttctatat cccgatttag tgttttggta atatgcacaa
    31381 cggcattatc taagtcaata tcagaccagg aaagagctaa agcttcattg atacggcaac
    31441 cagtagccaa taggaactta tagagtgttg tctcatagta gtaacgatat ctatgagtat
    31501 ctaaattatc gagataacca agaaattttt ttagttcttg attttcaaag tgctttactt
    31561 ttttccgctt tgctttctga gtgttacgag gtaaaacaac atcacgcgca ggattggacg
    31621 gtatagcctg catggttacg ccatactgta agatacgttt gtttaaagcg tgtatcttgt
    31681 cataatgtag aaaagccgct ttttcccctc tattagtctt gtcagcaagt tcgttgataa
    31741 ttgactggat aagtggagta gtgagcttat cgagcttgta agccccaaaa ataggcaata
    31801 tatgattatc gattagcttt ttaacattgc cttgagtgtt tggcttaacc gtattcttat
    31861 aactttccaa ccagagagtt gccaattctt gatagttttt tatggtaaca gccttttgtc
    31921 tggtagatcc tgctttttga aaagctattt tttcttgatt ggctttctgc ttaacttcct
    31981 tttgtgtccg acctgttact ttggttttta ctttctttcc tgttacctgg tcaactccta
    32041 gatatacatt agcacgataa actttgctac cgtctttttt tataacttca gttattttca
    32101 tgatgataaa cctttctaaa atacatcagc aggcaagcca ttatcaaaaa ggttttatat
    32161 catgctagga gctacgagaa cccccttatt ttcgttttat ttcttccagt aaagaataca
    32221 tagcattaat gtggttatat ttttgaaatt caggatcttg gttttgtgta ataaagtata
    32281 cgtattgtct accagatttg aatttatcga tagcttgttt ttccactaat ttttttaaat
    32341 attttaaaat tgtatttttg tggattttta gtttttcttc caaagcctct cttgttacga
    32401 aacggtgttc gattattaac tctaatatct ttttctcata ttcgttatca atatccagat
    32461 tatctataag ggaagtatcc cataatgtaa attcaactga gtctaattca gttcgtaaat
    32521 tgggatattt taaatgactc tctttaactg cttccattat tttgggtata ccagttcccg
    32581 ctttttcaca taaatttaaa aatctaaaaa tttcttgtat taagtagttt cttggatcag
    32641 aatgtgcccc actaaaaaag tcctttatgt caattctaag tgttccgcca tttgtgaata
    32701 tatacctgtc gggatatcta attatcatta tccctttttc gcttttatag tcgctatgaa
    32761 taaggctatt aatgaatgcc tcacgaattg caattcgtaa ttttgaaatt ccaattctat
    32821 tcatagaatt ttcttgaatg ttagagttgt catttaaagt tagatataat ttttcaataa
    32881 ctaggtaaaa gaaattaaaa agattatctt ccccccatgt accatcataa atcacacgat
    32941 ctttaaagcg attgttttca gaaaactctt ttagaacata ttctacgtta tagtgtggaa
    33001 taaactcttt tattgaatta tgtgtaccaa aaattaatag tccagcaact gttggcttta
    33061 ttttatcgtc cttgcgatct cttcgtaaag catttatttt tattaaaaat tgttcgttat
    33121 ccaactttga aaaagggtgc tccgcattta tattatcaaa tttttctcta tatagcttta
    33181 ttgtttctgt atctaagtct aaaatagaaa aatcctgaat aagtgtgcta tcaaaacttt
    33241 ccttagcgga atctcttaac atagagttga tttgctcttg tgaacaccta aaatcaccag
    33301 tcccctgacg aaaataggta gatgctatgt tgtcattaag atatataggt ttatccttgt
    33361 agtctacctt gttaacaggg ataatgacaa tctcttttcc ttttatattt acgacttcaa
    33421 cactttcttc attaatcaca tttctattaa ttttattagg gttattaagt aaactatata
    33481 attcgtccag tactttatcg ggatcattaa ctccagaaat ataaaaatct ttattctttg
    33541 tattctctga gacacctaga attaacagac cattatttgt attagcgaag gaacaaattg
    33601 ttttcatacc gtctttaggg aaagaatttt tagcttcttt gaattcaaca ccttggttct
    33661 cccctgataa taacaatttt ggtatatcgt attttctcat tttttctcca atcaatttgc
    33721 acacgcattc gcacacgcgc gggaaaaata gtttattttt agttagctaa cagtgctatt
    33781 aaaggttttt ttgaaagtag attattcgca cacgcattcg cacacgcgct tcaggattgt
    33841 tgaacattgt ggcgcgtggg ttagtctata ccccaaagta acgcaaaatc atctagattt
    33901 tctttatctt tcttagcttc ttgaagagct aaagacttaa tttcttcaaa tagattttca
    33961 aactttttat ataatttgtt gtaatattct tggttgaatt ccttatcttc aaaaactatg
    34021 tagaattcac tacttgtttt ttgaaataca atatctagcc agaataggat attacttgtc
    34081 tttagcgcaa gggcatttaa aacttcatag ttgtctttgg gattgtattc atttaatgat
    34141 tcagtgatag tagtgagaaa ctcttcagga ctgattggga aatttttact ctttgctagt
    34201 tcaattattt ccttgtctct tttctctctc tcttttactt tctgaaaaat tttatctttt
    34261 gaaacatttt ttacgaggta tttttcttcg tctaattgtt tatctaacat atataaaaat
    34321 tctttgtaaa catctttgtc agaaaagcga gggtcaagat cagatttttt cactcccaaa
    34381 taatcagcaa gtttttgaag attgccagat gttggcattg atctaccttt tacataacca
    34441 gttattgtac ttttaggaat ttctaaagca ttatgcaggt ctatctgtct gatacctttt
    34501 tctttcataa cacggttaag attattagag aaatattctc tattctttaa atcctgaggg
    34561 ctattttttg ccattgttaa aaactccctt actttaattc tacaacctga ttataacaca
    34621 aaaaagacaa agtacgaaaa aaataaaatt tttcaacaac agcgttgaca aagtacgaaa
    34681 aaaatagtac catgatttta tcaatcttga aaggagctat aagaatatgg cacaatggac
    34741 gctaagagcg tgtcgagtaa atgcaggttt tactttgcgc caagtggcta agaaggtcaa
    34801 caagaatttt cagactatct caaagtacga aaaagatagt acgctaatcc cttttgagct
    34861 acttaaagag ttatcggaac tgtatcaggt aaaactggac gatatttttt aggagatagt
    34921 acgaaaaaaa tagaactaaa tcaaaaggaa atctaagaaa ggagcaaacc aatggaatta
    34981 gtctacatgg acggtaagaa agagccgtat acactgagca gtattgttgc ggagtgtgca
    35041 gaagttaagc acagacattt gaagattttg ctgaataaac atcgagagga cttcgagagt
    35101 ttcggaaagg tgcaatttaa aatttcacct tcagaaagtg ggcaaaatgt acgggactat
    35161 attttgaatg agcaacaagc aaccttgctg atcacttact tacgaaatac agaacccgta
    35221 aaagagttta agaagaacct ggtcaaagca ttctttgaaa tgcgtgagga gctttctaag
    35281 ttccgtatgc agagggcgct agaaaagcca aaaagaaaaa ccttgcatga cagtatagag
    35341 acatgggagg caaaacccaa gcacgcgcat agcaccatga acaacctgct actaaaagca
    35401 gtaactgaca tgaacgctaa gcagttaagg gaagaacgtg ggggctataa cggtattgat
    35461 agcttgacca gtgacgagct ggagcaatac caggcatttg aggatatggt aatagccatg
    35521 atcggcttga atatgagtta ccaagaaatc aaggctatgg cattcagaaa taaaaaaaca
    35581 cgccaaagaa gcgcgtgaga gcaacaaaaa aggcttagca ataaccacac cgcagagcct
    35641 ttcacactaa cactaaaacg aatttaacaa agcaggcaag ctattatcaa agaggtttta
    35701 gtaaagattt atacctagat tatagcatat ttagggcaat ttgaccatac ggagagcgcc
    35761 aactctttaa actggtactt tctcatgctc tcaatttggc gactcagagc gtgaggctat
    35821 gaattgcaag aaaaactgta taagaaacaa ccattaaaaa cccccacact ctcggtcggc
    35881 aaacttctga gcgtgaggat atccagtata gtaaaaggca ttaaaagctc ttagagcaat
    35941 tacacaacat agaaacaaag gtaaaaaaca tgacagaaac aacatacgag aatttaacta
    36001 gacatataga cagaattagc gcagaaatgc gagaaattgg cgaaaaaaat gggcttagta
    36061 gactttcatt attggcaaat cagacaaaat tcatcaaaga aaatttacac cgtttacttt
    36121 ggattgaact tcctgaattg aatgacagcc ataaaatcga ggcagtttct aaaagcacta
    36181 cgggaatgtt tttccacgct ggtatttttg aaatggacgc tatgcgacaa gcattcttta
    36241 aacgccaagc tatgcacttt tttgacaacg aagcagagca acaggcgtat atagaacatg
    36301 ctgaaaagga gtatttagag gctactataa ccttaaaaga tattcttttt aactctaaaa
    36361 atggaactca gagagtaaat aaaagttgtc ttatagagaa gtttgaggag gcaatgcaat
    36421 gacactaaac ctagacaaca tgacacaagc agagtttgat gaagtaatgg ctgaaattaa
    36481 ggaaaaacgc cccaacctct tccagtttat tgctgatttt gtagatcgaa aagtaagcac
    36541 tgaggaggta gacgaatacc tgaagatgaa acatgaaaaa caagtggaat ttatcaagaa
    36601 ttatcaagcg agggcataac atgaatgagt tagatttgac caatacacaa tcggtaatct
    36661 ttatggtggt attgattggc ttactgcttt acctaaacca ccgagaccgc aaaaaaagcg
    36721 cccaatttga gcgagaaaac caacagagga tagaaacacc tagcgaggat ttaagccctg
    36781 attatgggcg ttatatccag cttgcagggg taagagttta cggaggaact gaatgagtct
    36841 atcagagaat gacaaacgag tattaagact aatcaaggta ggggctgaga actccataac
    36901 aggggcagaa atcagcctta taactaagct ggcggaaaga accgtacaag atattatcag
    36961 ccgtctaatc acgcgtcata gtgttcctat tgttggggtt cgccatggga catttagagg
    37021 atattttatc ccagctaaca aagaggagct actggacgga gcaaaggcat tctataacca
    37081 agtacaggaa gaacagaaac gcctaactgt ccttttgaat gctgatttag agagttacaa
    37141 agaaaccttg aaggaggtgg gcggatatgt ttagcctaag ccgagaaagt gagcaagacc
    37201 tagcgcatgg cattctggag gtagtagaaa gatacctgga agcgcgtgat acagtcaagc
    37261 cacgactgac aggtttaata tcagcccagg aagtcatgga cgagttagat ataaaataca
    37321 tgacactcca aaagtgggaa aaagcagggc taagacggta tcagccaccg ctagaagata
    37381 ctaggaaaat ctattataaa atatctgaca tctggaagtt tttgggggtg gaaaatggca
    37441 aggtatagta ttcatccggc agataataaa gggcattatc acaatattaa attttacaaa
    37501 gagcgcaggc caaccctaga ccagctaaag gaacagcaaa ggcttaaaaa gctgaagaaa
    37561 aaacgcaaaa aggggcgata gtatgacaat ttatgaggct aaaggctttc agagtaatct
    37621 tgtctatcca tttgataaaa ttgagccttt ccagtatatt gaacgattca agcccttagt
    37681 agttcctgaa ggggcagata ttgaggaata caagcgaact caagcgcctt actgtataag
    37741 tggcaaagtg acgccagaaa agcatggcag ttacaagcga aacaactcca gtctaatcta
    37801 tcgggatttg attttccttg attatgacga tatacagggg acgtctgagg gctttataaa
    37861 agccatttct agcgctttat ttggctactc ttacatctta tacccgacta tcaaacatag
    37921 cttagaaaag ccccgttttc gccttgtagt gaagcctgac aacgtgatga atgaggcgac
    37981 ctataagcag gtagtgaaag agattgctga caagattgga ctcccctttg atatggccag
    38041 tttaacatgg tcacaactcc aagggctacc agtcacaaca ggcgacccag caagttatca
    38101 aaagattgta gagcatggac ttgattatcc agtaccacag acaacggctg aaccagtcaa
    38161 acagaatgcg gcaagccttc catacactcc aaggccaagc gggcagaaat ctatgaccat
    38221 gaggatcatt gacacgcttt tcaacggatt tggagacgag ggagggcgca acgtagcact
    38281 gacacgattt gtaggcttac tctttaataa gtgggttgat tgtgacctag agacagccta
    38341 tgaacttaca aagatagcca atagcgtgac agttgaacca ttgccgattg aggagctaga
    38401 ccgcactttt agcagtatag cacgggctga atatagaaag agaggttaga accatagaac
    38461 tagaagaatt agcaaaccta aaaagtgaaa tcttggaggt aatggagcaa gaacaccctc
    38521 ctagaacgat gaaggagctt gaaaatcgta tctttaaagc tggagaagaa tggcgggcag
    38581 aacatactga aactaaggta aatgagaaca caggggacgt taccgaaaag gttgccatgc
    38641 cccaaacctt cacagtagct aaaatactga gcgagattgt cacatttact tttatcagca
    38701 agagcaatat acctgattat agcctactct atatctatga tttagacgag ggtatctata
    38761 ccgctagtaa tgatctattc aatcttttgt gtaagacctt tgacgttaga attaaaccca
    38821 gagagtggcc acagattaag ttaatggtta gaacattggc aaagatacga aaacctttag
    38881 aaagtgctaa cctcattccc gtacagaacg gcattatcaa cttagaaact aaggaactac
    38941 tcccctttag tcctaagtat gtaattacaa gtaagataag cacggcctac cacgcgccta
    39001 aacgagtccc aacagataga gagggaaaaa cttttgatga ttggttgaac tcaatcgctt
    39061 gtaatgatag tgaactggta acactgtttt ggcagattat ccttgaagct attaacccta
    39121 accatactcg aaataagttt gctatcttct acggggacgg taacaatggt aaagggacat
    39181 ttcagcgctt ccttatcaac ctgatagggg aaagcaatat atcagcctta aagcctgcac
    39241 agtttgctga aaagcataac ttggagacct tggtaggtaa ggtttgtaat attggggatg
    39301 aagcacctaa cgaatactta aaaaatccgt ctgatttaat gagtatcact agtggcgaca
    39361 ctgttctagt caatccaaaa ggacgcccag cctttgaagc tactttcaag ttattcaata
    39421 tcttttcagg gaattatatc cccaatggtg gcaacaagac aaaaggctgg tatcgtagaa
    39481 ttatgattgt cccttttaat gctgacttta acggggagaa ggaaaaacct tggataaaaa
    39541 atgagttttt agcaaacaag gaagtcctag aatatgccct ctacaaagct atcaatcaag
    39601 agccatttac tcactttatc gaacctaaag cagttaaagg actcctagaa gaataccagg
    39661 aagataatga ctacttactt tcatgggtta agcatgaata catggaaaaa ggttggcatg
    39721 agctggacgt agtacctgtt tttatcgtta caagatcact aaagcactat gccgaagata
    39781 tgggaatacc caagcccaat gtttacgggg ctggtaaaga aactatcaag cacttacaac
    39841 agttgacacc taatcggtat tctctaagaa agaaaagagt ttctccagaa gattttgaaa
    39901 aactagaggc atgggacgtt gacaagataa aaatgcggac acctcaacac tctatcacta
    39961 aacaagaata agtgtgacgt tctttttttg cttaaaccct tgataatact gattttcttg
    40021 aaaaaagtgt gacgttgtgt gacgttctca aaaaagaagg tcacacccct tgaagccttg
    40081 atatatctaa ctttagggga ataggtgtga cgttgtgaca ttctttccaa ctcttatata
    40141 tagagaaaaa tacagtattt atatatatag gaacgataaa acaaaagaac gtcacagggt
    40201 cacaggggtg gtgaaacacc tagagcctca agggtttgaa cgtgtgacgt tctttgtcac
    40261 aaaaggtcac agaaggtcac agaaaacgaa aaatattaca taatttacct taaaacaaag
    40321 aaatgacaac aacatgaaag ttaaactatt tgaatatact agacgatggg aaaaagaaga
    40381 ctttgagaaa gagatcgatg acttcatggc aactgttgaa gtgctggacg ttaaattttc
    40441 tggtacacca tctagtgaat cctttaattc ggtggctatc gtattggtat tatacagata
    40501 acaaaatggg gtagatagta ccgaccccct tgcaatggtg taactactag tgacaccctt
    40561 aaaaacagaa agaggaaaaa caacatgaca ttaaaaacat tttcatctaa agccaaaaca
    40621 tttactttca cttacgaatt taaagaccta gatacagctc tggtagcagg tcacgcgtta
    40681 ctgggatata tgactggaac atattgccag cctgtaatct cattgaccta caaggataaa
    40741 ggcacgctag tagctgagta tgtggaagat cacaagctaa acaagacctt taagcgtatt
    40801 tgtgacagtt ttaaagacta ccacaaacaa ccaggagagg ctgaagcatt tgaagaacgt
    40861 tacaaacggg agcgcgtgct ccaactcaaa gagtcagagg actttgagag tttactgaat
    40921 aaggtcacag actacgagct ggaactatta gactatgctg accgcctgct ttctgataag
    40981 cctatcccta tggactctat gactgctttt gctacgttgg aaatgctggg cgatgaaagt
    41041 attagcctac tccaaaagtt ggacgtagag ggcgaatata aaggccttgc tggttataca
    41101 gagcatttga agtagaatac aggggagcaa tccccttttt gctatcaagt caatagtttt
    41161 gggtttttcc atataggggg aaataatgaa gcagttagca atagaagcaa tcactaaacc
    41221 aatgaagctg agaggaatat ctaagggtat agccgagttg gatggtcaac gtttagagat
    41281 tgatttggat agtttaatga ttgattttgg tggagagtca tttgaattag acagaatagc
    41341 aggaactaag ggaggtaatc gatatttttt tctttgccct gattgtggta gacggtgcag
    41401 gttgctttat aaacggtatt tgtattttag ttgcggtact tgtctagata tccacaagca
    41461 caccctgaac cgcagtaaaa cggattgcca atactactgg gagcttgcac taaaagaagc
    41521 tagaaaggta gaaccagggt ggagtcctag acgtggcgga tatatgtttg atagttttcc
    41581 tgaaagacca aaatacatga aacagaaacg atattacaag cattatcaaa agtttattaa
    41641 ctacaccaga aaaggggata gcttttggct gaatggtttg agttctctaa ggtaatttgt
    41701 agtagtgtgc aatttacaaa acaaacaaat actacatatt agacggtttg aatgttaaaa
    41761 aagctagata tatcaaggat ttaattaagt atagcgttcc aaaaaaaggg tgcagtaagc
    41821 gttccaaaaa agggtgaggt aagggtgagg ttgaatattt aaaaaaggct aagattaggc
    41881 taaggtcaca tacttcaaaa tagcaaggtt ttagcaaggt acagggcttt tttctagtga
    41941 tagaacccca aggttaccac aaggtatagc tactttttta gaaccataga acggtaaggt
    42001 tacggtaagg tatcgaagtt ttccaatggt aaggttttgg taaggtagca tatataaaaa
    42061 gtacaaggtt agtacaaggt tacatactta aaaatactaa ggttttacaa aggtagagag
    42121 gtttaccgag ggttagaaaa ggtgagattt tgcttaggta gtggcagtaa atatgcctga
    42181 caaatggcag ggttatgtgt gttgaactcc gagcgaacgc cgagaaagtg gctatatccc
    42241 ccctatcatt tatcaagtag ataagagcaa taaaaaccct ccttaacccc ctgagaaacg
    42301 acaagcagat aagagaagtt tttagccctc ttatttcgga tctactcctt gcagaatgac
    42361 aagcagataa ggacgacaat aagccttctt aactgcttac aaaacgatag ggagttaaga
    42421 cgaatttaaa agccccttat tttcgttttt ctccttgtca aacgggaagg aaataagaca
    42481 ggaaataaca tcgcttattt tgattttgct ccctgaaaaa ctgtaaggag ataaggagac
    42541 ttattagctt ccttaatttg aattttctcc ttacaaaatg acagggaaat aagaactaaa
    42601 ataactcccc ttattttcct accaaatgat aaggagataa gagcagttta aaagtctgtt
    42661 attttggatt tgttgcttac aaaatgataa gcagataagc aaagaaataa cttgccttaa
    42721 ttgcttgcag aatgacaagg aaataagaga gataaaaaca tcccttaatt gcttatcaaa
    42781 tggtatggag aatggacttg aacctagagc gaagctagag aaaatgaaaa aaagccagca
    42841 cagggctgac tcctttatga attattccat aaaactatta tatcacaaag gaggccgagg
    42901 catgacacca gagcaagtaa aagaaaaact agagggcgtt aagtggataa acaaggagat
    42961 caaaggctta tatttggaat tggaaaccct ggaaggtggc attatcaaaa aaccaacact
    43021 aagccatagc agggtgcaga caagtagaga gaataagaca gagaacaatc ttataagtgt
    43081 tctgaagcta aaagaggaca ctttacagag aattgagcga cttactgaag agagaatgaa
    43141 aatatctgag ctaatcgata aactggccaa tccgcttgag cgttctgttc taagactttt
    43201 ttacttgaat gatcttgtag tttcggaggt ggctgaagaa atagatagat caaatactac
    43261 agtatacatt ataaggcaaa aagctataga acacttaaca ggtattgtaa acggggattg
    43321 atttaacctt accacggaat taggagagta tgggggagtc ctaagccaca tattcgcccg
    43381 tatttcgctt tgtttcgtac tggacaacta aaacaccatg gataaactac aaaccctcag
    43441 aaacgaatct gggggctttt gtgaggtcat aatcttataa accacgcgct tcatggtata
    43501 atatatctat cagcaaccag caataaaaaa gcacgtttga ccgtgctagt ttcttgcctg
    43561 ctgaactcgt caaatcttag cccttttgtg gggctttttt gctccccttt ttgcgtactt
    43621 tgggggagca agtagtaaaa agtaatgtta gtaattttta ttaaaaagcg cgtgatataa
    43681 gggttaggaa gccctaagga aacataaaat aagcgattgt tgattatact acaaaatcgg
    43741 ccttttgggt aatagaatct cacttttttt ggtataatgg taagcaataa tggactagaa
    43801 agaacaaaga tgcaagataa aattgtcatt catggggcgc gtgcccataa tttaaaaaat
    43861 attgatgtgg agattccgcg agacaagttg gttgtcgtga ctggcttgtc aggttcaggg
    43921 aagtccagtc tggcttttga tactctctat gcggagggac aacgtcgcta tgtagagagt
    43981 ttgtctgcct acgctcgtca gttcttggga aatatggaaa aaccagatgt agatgccatt
    44041 gatggtctca gcccagctat ttccatcgac cagaaaacga ctagtaaaaa tcctcgctcg
    44101 acggtgggaa cgacgactga aatcaatgac tatctgcgtc tcctctacgc acgtgtgggg
    44161 acgccttact gtatcaacgg acatggagct atcaatgctt cttctgtgga gcaaatcgtt
    44221 gataaggttt tggagttacc tgaacgccag cgcttgcaga tcttggctcc tgtcatccgc
    44281 aagaaaaaag gccaacataa gagtgttatc gagaaggttc agaaagacgg gtatgttcgt
    44341 gttcgtgtgg atggggaagt ctatgatgtg accgaagtgc cagagttgtc taagagcaag
    44401 caacacaata tcgatgtcgt ggttgaccgt attgttatca aggagggcat tcgtagccgt
    44461 ctctttgatt ccattgaagc tgcccttcgt atcgcagaag gttatgtgat tatcgacacc
    44521 atggacgact ctgagttgtt gttctctgag cattatgcct gtccagtttg tggatttact
    44581 gtcccagagt tagaacctcg tctcttctct ttcaatgctc cctttggctc ttgtagtgag
    44641 tgtgacggct tggggattaa gctggaggtg gatactgatt tggtagtgcc agatgccagc
    44701 aaaaccttac atgagggagc gctggcacct tggaatccta tctcatccaa ctactatcca
    44761 aacatgttag agcaggccat gaaagtcttt ggagtggcta tggataagcc ttttgaggac
    44821 ctgtcagaag aagataagaa cttgattctc tatgggtcag atggtaagga attccatttc
    44881 cactatgaga atgaatttgg tggcgtgcgc gatatcgaca ttccgtttga gggagttatc
    44941 aataatatca aacgtcgtta ccatgaaacc aatagcgatt acactcgcac tcagatgcgt
    45001 ctctacatga atgagctgac ctgcggaacc tgtcaaggct atcgtctcaa tgaccaggcc
    45061 ttgtctgtcc gtgtgggcgg ccagcaaggg ccacatattg gagaaatctc agacctgtct
    45121 atcgctgacc acttggactt ggtgagccag ttaactttgt ctgaaaatga agccatcatt
    45181 gctcgtccca ttctcaagga aatcaaggat cgtttgacct tccttaataa tgtgggtctt
    45241 aactatctaa ccctgtcacg ttcagcagga accctttcag gtggggaaag tcagcgcatt
    45301 cgtttggcaa cccagattgg ttccaaccta tcaggcgtcc tctatatcct agacgagccg
    45361 tcaatcggtc ttcaccagag ggacaatgac cgcctgattg ccagtctgaa aaagatgcgt
    45421 gacttgggca atactcttat cgtggtggaa cacgacgaag ataccatgcg tgaagctgat
    45481 tatctgattg acgttggtcc tggtgccggt gtttttggtg gtgagattgt tgcagcaggt
    45541 acacctaagc aagtggctcg caacagcaag tctatcacag gtcagtactt gtcaggcaaa
    45601 cgtgtcatcc cagtaccaga agagcgccgt gtcggaaatg gtcgttttat tgaagtgata
    45661 ggagcgcgtg agaacaactt gcaaaatgtc acggctcgct ttccactagg aaaatttatc
    45721 gcagtgacag gtgtgtcggg ttcagggaaa tcgactctaa tcaacagcat tctcaaaaaa
    45781 gccattgccc agaagctcaa ccgtaattca gacaaacctg gtaagtttaa gactattaca
    45841 gggattgagc atgtcgaccg tttgattgat attgaccaga gccctatcgg acggacgccg
    45901 aggtctaacc cagctaccta tacaggagtt tttgacgata tacgtgacct ttttgctcag
    45961 acaaatgaag ccaagattcg aggctacaag aaggggcgct tcagtttcaa cgtcaaggga
    46021 ggtcgctgtg aagcttgctc aggtgacggg attatcaaga ttgagatgca cttcttgcca
    46081 gatgtttatg tggcttgtga agtttgccac ggaacccgct ataacagtga aaccctagaa
    46141 gttcactaca aggaaaagaa tatttcgcag gtcttggata tgacggtcaa cgatgcggta
    46201 gaatttttcc aacacattcc gaaaattcaa cgcaaactcc agaccatcaa ggatgtaggt
    46261 ctaggctatg tgaccttggg acagccagct accacccttt ctgggggaga agcccaacgt
    46321 atgaagttag ctagcgaact ccacaaacgc tcgacaggaa aatctttcta cattctggat
    46381 gagccgacga cagggcttca tacagaggac attgctcgcc tgctcaaggt tttagctcgc
    46441 tttgtagacg acggcaatac agtcctcgtc atcgagcaca atctggatgt tatcaagacg
    46501 gcagaccata tcattgactt gggacctgag ggcggtgtcg gtggtggaac catcatcgta
    46561 acaggaactc cagaagaagt agctgccaac gaagccagct atacaggaca ctatttgaaa
    46621 ggaaagttac atcatgaata aacgcgtaca agcatttcta gctaaaatgc aagaaaaaga
    46681 actagatggt atcatcatca acaatcttaa aaacgtctat tatttgactg gtttttgggg
    46741 ctcaaacgga acagtcttta tcagccgtga ccgtcaggtc ttagtgacag actctcgcta
    46801 tatcatcgca gctaagcaag aaaccagtgg ttttgagatt gtggctgatc gtgatgaatt
    46861 ggctgtcatt gcaggaattg ttaaggacat gggcttgact cgtatcggtt ttgaagatga
    46921 gatttcagtg tcttattacc accgtatgca ggcagctttt gcaggtttga acttgcttcc
    46981 acaaactcag tttgtggaag gtcttcgtat gattaaggat gaggcagaga ttgcagcgat
    47041 tcgcaaggct tgttctatct cagaccaagc tttccgcgat gcgcttgact ttatcaaacc
    47101 aggaaaaact gaaattgaga ttgccaactt ccttgacttc cgcatgcgtg agttgggagc
    47161 atctggctta tcttttgata cgatcctagc tagcggtatc aattcttcta aaccccatgc
    47221 ccatccaatg cacaaaccag tggagttggg agaagccatt accatggact tcggctgtct
    47281 ctatgaccac tatgtcagtg atatgacccg gactatctat ctagggcatg ttagcgatga
    47341 gcaggcagag atttacaata cggttctaaa agctaaccaa gccttgattg accaagctaa
    47401 ggcaggctta ggtttccgtg actttgacaa aatccctcgt gatattatca ttgaggcagg
    47461 ttatggcgac tactttactc acggcattgg ccacggtatt ggtctggata tccatgagga
    47521 accctacttt agccagactt ctacagaaac tattaagaca ggtatggcct tgaccgatga
    47581 accaggtatc tatatcgaag gcaaatatgg cgttcgtatc gaggatgata tcctgattac
    47641 agagacaggt tgtgaattat tgaccctagc tccaaaagag ttgatagtca tttagttgtt
    47701 tgtcaagaaa aaagtacgaa aatgacgaaa aaagtcaaaa aaaattaaaa ataggtcgca
    47761 agtcggatgt tttttatggt ataatagact aaactgatag taacatgtag cgaaaggggt
    47821 aggtacatga ttaaaattta tacagtctca agttgtacta gctgtaaaaa agcaaaaacc
    47881 tggctcaatg cccaccagtt aagttataaa gaacaaaacc ttggtaaaga aggaattacg
    47941 agagaagaat tactggatat tctaaccaaa acagataacg gaatagccag catcgtttca
    48001 tctaaaaatc gctatgccaa agcccttgga gtggatattg aagatttgag tgtcaatgaa
    48061 gttctcaatc tgattatgga aacaccgaga attttaaaga gcccaatcct tgtagatgaa
    48121 aaacgcctgc aagttggcta caaggaagac gatattcgtg ccttcctacc acgctctgtc
    48181 cgtaatgtag aaaatgcaga agcacgtttg cgtgcagctc tataaacatc aaggctggga
    48241 gcacttccca gtcttattct attttaattt caaaaagaaa gaagaaagaa atgaaaaaaa
    48301 tagttcttgt tagtctagct ttcctttttg tcctggttgg ttgcggacag aaaaaagaaa
    48361 ctggaccagc tacaaaaaca gaaaaagata cgcttcagtc ggcattgcca gttattgaaa
    48421 atgctgagaa gaatacagtt gtaactaaga ctttggtctt gcccaagtca gatgatggta
    48481 gccagcagac acaaacaatt acttataaag acaagacttt tttgagtcta actatccaac
    48541 aaaaacgtcc agtctctgat gagttgaaga cttatattga ccaacatgga gtggaggaaa
    48601 ctcaaaaagc tcttcttgaa gcggaggaga aggataagtc tatcattgaa gctcgtaaat
    48661 tggcaggttt caaacttgaa acaaaactat tgagcgcaac ggaacttcaa acaacgacta
    48721 gttttgattt tcaagttctg gatgtcaaga aggcttccca gttggaacat ctgaagaata
    48781 ttggtttgga aaatcttttg aaaaatgaac caagcaaata tatttcagat agattggcaa
    48841 atggcgcgac agaacaatag aaaatccaaa taaatagact gcctgaattg tagaaggtaa
    48901 ggaattatgc tataatggta ctattctaag gaaagagggt gttagaatgg gatttactga
    48961 agaaacagta cgttttaaat tggacgattc caataaaaaa gaaattagcg aaactttgac
    49021 agatgtttat gcttcgttga acgataaggg ttacaaccca attaaccaaa tcgtaggtta
    49081 cgtattgagt ggagaccctg cctacgttcc tcgttataat aatgcacgaa atcaaatccg
    49141 taagtatgag cgtgatgaaa tcgttgagga attggttcgc tactacctca aaggacaagg
    49201 agtcgatcta taacctatga gaattatggg attggacgtc ggttcaaaaa cggtaggggt
    49261 ggcgattagc gatccgcttg gttttacagc tcaagggctt gaaatcatcc agataaatga
    49321 agaacaaggc caatttggtt ttgaccgcgt taaggaattg gttgatactt acaaggtgga
    49381 acgatttgta gtgggcttgc ctaaaaacat gaacaataca agtggaccgc gcgtagaagc
    49441 tagtcaagcc tacggagcaa agctagaaga gttttttggt ttaccagtag actatcagga
    49501 tgaacgcttg acaacagtgg ctgctgagcg catgttgatt gaacaagcag atatcagtcg
    49561 caataagcgc aagaaagtca ttgataagtt agcagctcag ctgattttac aaaattattt
    49621 agatagaaaa ttttaatata aaggagaggc tatgtcacac gatcataacc acgaccacga
    49681 agaacgtgaa ctaatcacac tagtagatga gcaaggaaat gaaaccttgt ttgaaatcct
    49741 tttgacaatt gatggaaaag aagaatttgg taaaaactat gttcttctag taccagttaa
    49801 cgcagaagaa gacgaagacg gacaagttga aatccaagct tactcattca tcgaaaacga
    49861 agatggaaca gaaggcgaat tgcaaccaat cccagaagac tcagaagacg aatggaacat
    49921 gattgaagaa gtcttcaaca gctttatgga ggagtgatac agtctgggag actgtatcag
    49981 cccaactccc agaaatgggg aagagttgga acgtccagtg aacattttta ccccaactct
    50041 tagaaattga gaagagttgg aacatctagt ggatgttttt agcccatatt cacattcata
    50101 gtggctagtt attagctaac caggtaagag gtcgggacga aaatcctggc cttgttttta
    50161 ttagtaacca tactttaatg cgataattga ttggactttt gtcaaggaga tgtgtatgtt
    50221 tgaagtagaa gaatggctcc atagtcggat tggtttaaat tttcgatcag gtttgggccg
    50281 aatgcagcaa gcggtggatt tgttaggaaa tcctgagcag tcttacccta ttatccacgt
    50341 aacagggact aatgggaaag gatctaccat tgcttttatg agggaattat ttatggggca
    50401 tggcaaaaaa gttgcgacct ttacctcccc tcatatcgta tccatcaatg accgaatttg
    50461 cattaatggg caacctatag cagacgcaga ctttatccgt ttggctgatc aggtcaagga
    50521 gatggagaaa acgcttctgc aaactcctga ccagttgtcc ttttttgaat tgctgacctt
    50581 ggttgctttt ctttatttta gggagcaaga ggtggatttg gttttattag aagtgggaat
    50641 tggtggctta cttgacacga ccaatgtggt aactggagag cttgctgtca tcacctccat
    50701 tgggcttgac catcaagaaa ccttgggtga tagtctagaa gcaattgcag agcagaaagc
    50761 tggtattttc aaggctggta agaaggcagt gattgcgaaa ttgcctccag aagctaggct
    50821 tatctgtcag aaaaaagccg aatctttagc tgttgacctt tatcaggcag gtcaagattt
    50881 ttcagtgctg aatggtgatt tttcaagctc tttactaaat ctttcacagc tgaacatagg
    50941 cttagaagga gcctatcagc aggagaatgc ggccttggcg ttgcaaactt ttcttctttt
    51001 tatgggagaa agaaaggaag ctattgatga acaggctgta agaaagacct tggaacaaac
    51061 ccattgggct ggtcgcttgg agcgtattcg cccacagatt tacttggatg gtgctcataa
    51121 cctccctgcc ttgactcgct tggttgagtt tatcaaagaa aaagagcagg aaggctatcg
    51181 acctcaaatc ctctttggat ccttgaaacg taaggattat caagggatgt tgggttatct
    51241 gactgaaaat ttacctcaag tggaactcaa aatgaccggc tttgactatc aagggtcttt
    51301 ggacgagaca gatgtaacag gttaccatgt aattccctct taccgagaat ttatcagcag
    51361 tttcgaagaa agggcagacg ctcaagactt gctgttcgtt acagggtctc tctattttat
    51421 ctcagaagta cggggctacc tgctggaccg tgagcagata aattgacccc cttttttgaa
    51481 cttgttatac taggggaatt gctggttaga gaaaatttct ctaaattggt agcagaaagg
    51541 aaattcatca tgaaattaaa aagattcaca ctttctcttg cttctctagc aagttttagt
    51601 ctcttagtag cttgttcaca aagagctcaa caggttcaac agcctgttgc tcagcaggtc
    51661 caacagcctg ctcaacagaa taccaatact gcaaatgcag gaggtaacca aaatcaagcg
    51721 gctccagtac aaaaccaacc tgttgctcaa ccgaccgata ttgatgggac ttatactggt
    51781 caggatgacg gagaccgtat cactttagtg gtaactggaa cgactggtac atggactgag
    51841 ctcgaatctg acggggatca gaaagtcaaa caggttacat ttgattcagc aaatcaacgc
    51901 atgattattg gcgatgatgt caaaatttac actgtaaacg gtaatcaaat cgtcgtagat
    51961 gatatggata gagacccatc ggaccaaatc gttttaacta aataagacta tgcaagtaga
    52021 aagggctgga tttttcagcc tttttacttt tacctagaaa ataatcataa atacttgcct
    52081 tctaccgaat acctgcgtta tactagtatc aattacttgt ttttagcatt caaactatca
    52141 aggaggggat atgaaatata ggaaatttca attattgatg tccaagtatg gctttagtct
    52201 ttcgattatg ttacttgaac tttgtcttgt ttttggtctc tttctttatt taggacgcat
    52261 ggctcccatt ttatggatta ctgtcctcat tctactgagt atcatcacaa tcatttcgat
    52321 agtcaaccgt aatacgactc ctgagaataa ggtaacctgg ttgttagtag cctttgtgcc
    52381 agtatttggt cccttgctct atctgatgtt tggtgaaagg cgattgtcca aaaaagaaat
    52441 caaacaactg aagaagctag gctctatgca tttccaagaa gcaaatagcc agctactaaa
    52501 agagaaatta aaagaaagtg acaaggcagc ttatggagtc atcaagtcct tattgagtat
    52561 ggataccaat gctgacatct atgatcaaac tgcctctaca ttttttccta acggagaagc
    52621 tatgtggaaa aagatggtag aagatcttaa aaaggctgag aaatttattt tcttggaata
    52681 ttacattata gaagaaggtt tgatgtggaa tcgcatacta gatatactag agcaaaaggt
    52741 agctcagggt gtagaggtta agatgctcta tgatgatatc ggctgtatgg ctactttaac
    52801 aggagattat gcacatcgac ttcgtcagct gggcatcgag gcccataaat tcaataaagt
    52861 tattcctcgt ttgacagtgg cttataataa cagagatcat agaaaaatat tgattgttga
    52921 tggtcagata gcctatactg gtggggtcaa tctggcagat gagtacatta accacgtcga
    52981 gagatttggt tattggaagg atagtggaat tcgcttagac ggactagcag taaaagccct
    53041 gacacgctta tttttgacca cttggtacat taatcgagga gaaattagtg attttgatca
    53101 atatcattta gaaaatcatt ctatcccgag tgacggttta accattccat acggaagtgg
    53161 acccaagcca atttttcgag cgcaggtagg gaaaaaagtt tatcagagtt taatcaatca
    53221 agcaacggaa tcggtctata ttacgacacc ttatttgatt atagattatg atttaacaga
    53281 gacaatcaaa aatgcagcta tgagaggggt cgatgttcga attatcaccc cttacatacc
    53341 agataagaag ttcattcagt tagtcacgag aggagcttat cccgaccttc tttctgctgg
    53401 tgttcggatt tatgagtata gtccaggttt tattcatagt aagcagatgt tggtagacga
    53461 agattttgcg gtggtgggga caatcaatct cgactaccgg agcttggtac accattatga
    53521 aaatgcagtc ttactctata aaactccttc tataagggaa atcgcccgag attttcgaaa
    53581 tatatttgca gattctcagg aagtctatcc tcattctatc aaaacgagct ggtatcaaaa
    53641 gcttgtaaaa gaaatcgccc agctattcgc ccctatctta taagaaatct agaacttagg
    53701 atacaaacca gacctatttt tcttgtcttt tacgaataga aagaaagagg aggggaattc
    53761 atgctaacta aggaagaagt gaatgatatg attgagttca aacagacaca tttacaccgc
    53821 tttcgggaaa ttgaaacctt tgtgaaacta tgcaaaaaat cactcaaaca gccatcgcaa
    53881 gctgacaatc ctaggacttt ttgatatact aagacagata aattgaacag gagaaacgat
    53941 atgagtgtgt atggtagagt agaagaagtt cataaggaga atcgtgaacc tctagaatac
    54001 caaatcgaac aagaatcgca tcatcgtgaa tcaagtcgtc ttcctttagt gaaaatttta
    54061 ctatggagta cgcttgtaac ggggataact ctaggagtac cgctattact cgacttaatg
    54121 agtgcacaag aagtgcagga tttttatgca ggttgggcgc ttcatcagac agggaagatt
    54181 tacagcgact attatggaag tcaaggtttg ctttattatt tgctgactta cgtgagtcag
    54241 ggcggatttt tctttgccat ctttgagtgg ttagccttgg tagcaggcgg atttttcctt
    54301 tttagatcag cggacacctt gacagagcaa ggagaccaag ctggacatct ggtgactatt
    54361 ttttacatgc tagttacagg tcttgctttt ggtggaggct atgcgactct tttagcgctt
    54421 cctttcttat tcgcagcctt tagtttagtt gcggcttacc taagcaatcc aagccatgat
    54481 aagggatttg tacggattgg gctagctttg gcaggcggat ttttctttgc tcccttatca
    54541 tcgctcctgt ttattgctgt agtgagttta ggcttgttgg tctttaacct tgggcataga
    54601 cgctttgcgc atgggtttta tcagtttctt gcagtggctt taggtttttc acttgtcttt
    54661 tatccaactg cctactatag tgctgcaaca ggaagttttg gggatgcgat tagtggtatt
    54721 cgttatccta ttgacagtat tcgctttgat tttacttcta aaattttaga gaatatgttt
    54781 ttttatggct tgttgtccct tggtttggga tttgtggttt gtatcttttt aggtctcttt
    54841 caatccaaac cctttaaact atacgtcatt tcggttcctg caagtcttgt ggtaatttta
    54901 ggtttgattt tacttttctt ttcacaagag cctctgcacg cttcttattt gatggtcgtc
    54961 ttccctgttt tcctactttt attggtaacc aatattaaga gtcaacagag ggggcgtagt
    55021 gctagaagaa gccgaagaga aacgccagtt agcctatgga gtcgtttctt caaaggaaat
    55081 ctatatctgc tagtttttgg gtttgtctat cttttgtctg ttcctttttt gatgaagttt
    55141 gtcctttatc cagtacctta tcaagaacgt aatcgtcttg ctgatttggt aaaagaggag
    55201 acaaatacgg aagatgctat ctatgcatgg gatgatactg cgactcttta tcgtaagagt
    55261 gagcgcttgt cgccatcggc gattttgtcc ccgttgcact atacagcaac tgaggaaaat
    55321 cgtaataagt tacttaatga cttgaaagaa aaacaaccta aggtgattgt ggtaaatgat
    55381 aaggtggtag tctggtctga agtggaaaca ctcttaaaag aaaattacca acaagtaaag
    55441 actgattact cagagtttaa agtctataaa attaaataac caaatcaata tcttgtgtat
    55501 ttttaaaaat tttaggattt ttaacacaag atattgattt ttctttttag agtggtataa
    55561 tactttttag aaagaacatt ttagaaaaga gcatgcatat gattgcacta gaagaaaaaa
    55621 ttacaatttt gccaactctc ttcgtcgaga aacgagatgg gagacgtgtt gtatttgatg
    55681 tggacaagat tgacaaggct ctccacaagg cggctgacaa ggttatggat gtgacacccc
    55741 tggttgaaaa atgcctcaat gatctgactg agcgaattat tacagaaatt catagtcgct
    55801 ttccacaggg aattaagatt tacgaaattc aaaatatcgt agaacatgaa ctccttgaag
    55861 ccaaagaata tgcgctggct gaggagtata ttacttatcg gacacagagg gattttgagc
    55921 gctcaaaagc gacggatatc aactttagta ttcataaact tctcaacaaa gaccagacag
    55981 ttgtcaatga aaacgctaat aaagacagtg atgtctttaa cactcagcgt gatttgacag
    56041 cagggattgt tgggaaatca atcggactgc aaatgcttcc taagcacgta gccaatgccc
    56101 accaaaaggg ggatatccac tatcacgatt tggactacag tccctatacc cctatgacca
    56161 actgctgttt gattgatttt aagggtatgt tggaaaatgg ttttaagatt ggaaatgcag
    56221 aggtagagag tcccaagtct atccagactg cgacagcaca gatttctcaa atcattgcca
    56281 acgttgcttc tagccagtac ggtggctgtt cagctgaccg tatcgatgaa attttggcgc
    56341 cttatgcaga gaagaattat caaaaacatc tcaaagatgc agaagagtgg gtattgcctg
    56401 aaaaacagga agattacgct tggaagaaag cgcaaaagga catctacgat gccatgcaat
    56461 ctcttgagta tgaaatcaat actctcttca cttcaaatgg acaaacacct tttacttcgt
    56521 taggttttgg tctgggaacc agtcgttttg aacgagaaat tcaaaaagct attttaaaca
    56581 ttcgcatcaa gggtcttggt tcagaacacc gtacggctat ctttcctaaa cttatcttta
    56641 cgcttaaaag aggcctcaac ttagaggaag gaactcccaa ctatgacatc aagcagttgg
    56701 ctctagagtg tgcaaccaag cggatgtatc cagacgtttt atcttacgat aagattgttg
    56761 acttgacagg atccttcaag gtgcctatgg gttgccgttc tttcctccaa ggatggaagg
    56821 atgaaaatgg tgtagaagtc aattcaggtc gcatgaatct gggtgttgtg acggttaatc
    56881 tgcctcgtat tgctcttgag tctgaaggtg atatgaataa gttctgggaa atcttcaacg
    56941 agcgaatgaa tatcgcagaa gatgctcttg tttaccgtgt cgaacgcact aaagaggcga
    57001 caccagcaaa tgctcctatt ctttatcagt acggtgcttt tggccatcgt ctaggtaaag
    57061 aagaaagtgt tgaccagctc tttaagaatc gtcgtgctac cgtttcgctg ggctatatcg
    57121 gcttgtatga agtagcgaca gttttctttg gtaacagctg ggaaagtaat ccagatgcta
    57181 aggaattcac gctagacatc attcacgata tgaaacgccg tgtagaagag tggtcagacc
    57241 aatatggcta ccatttctct atctactcaa caccatccga aagtctgaca gaccgtttct
    57301 gccgactaga tatagacaag tttggctcta ttcctgatat cacagacaag gaatactaca
    57361 ccaactcttt ccactacgat gttcgtaaaa atccaacacc gtttgaaaaa ttggactttg
    57421 agaaagtcta tccagaagca ggtgcgtcag gtggtttcat ccattattgt gagtatccag
    57481 tccttcagca aaatccaaag gccttggaag ctgtctggga ttatgcttat gaccgtgtag
    57541 gctatctagg caccaatact ccgattgacc gttgctacaa gtgtgacttt gaaggggatt
    57601 ttgaaccaac tgagagaggg tttgcttgtc caaactgtgg caatagcgac cctaaaacag
    57661 tagatgtggt gaagcgaact tgtggctacc taggtaatcc tcaagcaaga ccgatggtca
    57721 acgggcgtca caaggaaatc gctgcgcgtg tcaaacatat gaatggttca acgattaaaa
    57781 tagctgggca tcaagtaaca aattagaaag aaatgaaatg ggaaaatatc aactagacga
    57841 taaggggcgc gcacaagtga cccgttatca cgagaaacac tctaaaggtg gagctggtaa
    57901 gaaagaacgc ttgcttagct tcagagaaca atttttaaac aagaacaaga aaaaataaaa
    57961 gtgagagcca gctctcgctt ttctcatagt gggaggtaag gatggaatta cgcagaccaa
    58021 gattagcgga taagaaagct gttttagata tgatgacaga gtttgaaaag agccaatcag
    58081 cccatgatgg aggattttgg gatgttgagg atttttctta cgaggagtgg ctagaaggta
    58141 accgtaataa agaaatggga atatggctac ctgaaaatcg cgttccatcg atacagttcg
    58201 tattgtttgg tgaatcaggt tgtgctctag gatttttgaa tctgcgattg agactgaatg
    58261 aggggttact gaattatgct ggccacattg gctactccat ccgtccatct gaaagaggca
    58321 agggttatgc aaaagagact ctccgtcagg gcttgcaagt tgctaaggaa aagaacatca
    58381 agaaagctct ggtgacctgt agcgtgaata atcctgctag cagagcagtc attctagcaa
    58441 atggtggaat atttgaggat gctcgcaatg gagtcgagcg ttattggata gaggtagcga
    58501 atgaataatc caaaaccaca agaatggaaa agcgaggaac ttagtcaagg tcgtatcatt
    58561 gactacaagg cctttaactt tgttgatggc gaaggcgtgc gtaactctct ctatgtagca
    58621 ggctgtatgt ttcactgcga ggggtgttat aatgtagcga cctggtcctt caatgcaggc
    58681 attccctata cagctgagtt ggaagaacag attatggcag atcttgccca gccttatgtt
    58741 caggggttaa ccttactagg aggggagcct tttcttaata ctgggattct cttgccactt
    58801 gttaagcgga ttcggaagga attgccagac aaggacattt ggtcctggac cggctacact
    58861 tgggaagaaa tgatgttgga aactccagat aaactggaac tcttgtcact gattgacatt
    58921 cttgtcgatg gaagatatga tcgaactaag agaaatctta tgctccagtt tcgaggttcg
    58981 tctaaccaac gaattatcga tgtgcaaaaa tcgctcaaaa gtgggcaagt agtgatttgg
    59041 gacaagctca atgacggaaa agaaagctat gaacaggtga agagagaatg aagaaaaagg
    59101 acttagtaga ccaactagtc tcagagatcg agacggggaa agtcaggaca ctgggaatat
    59161 acggtcatgg agcttcaggt aaatcaacct ttgcacagga attgtaccaa gctttagatt
    59221 ctactacagt aaatttgcta gagacagatc cttatatcac ctcaggacgc catctggtag
    59281 tacccaagga cgcgccgaat caaaaggtga cagccagtct gccagtggcg catgaactgg
    59341 agagtttgca gagagatatc cttgccttgc aggcgggtat ggatgtcttg acaattgaag
    59401 aaccttggaa ggctagtgag gtcttgtctg gagtcaaacc aattttgatt gtcgaaggga
    59461 tgtctgttgg ctttctaccc aaggaactct ttgaaaaaac catctgtttc tacacggatg
    59521 aggagaccga attaaagcga cgccttgcta gagatacgac tgtgagaaat cgtgatgcat
    59581 cctttatatt ggctagccat cagatgagac gggagcagta tctgcgatac tataaagaaa
    59641 ctgagtctaa ggcggatatc ttagtggatc aatcagaaga taaatttgat gtcaagagga
    59701 cttaacttat gtatagaaga aatatagaag aaaatcccta attttaggaa gaaaaagtag
    59761 gaaaacagtt tcatcccaaa aaaacgaaaa aacctaacaa atcccttgca atcgcagggg
    59821 atttgtgtta ttctattatg gtgctgtaaa ttacagcctt agttttgata caagaggttg
    59881 cgacacgctc ggttgcattg ccacgcaaca ccgtgtcggt tttcttgtgg agctagccta
    59941 ttatcttaga tagacgaaaa ggagaaaaag atggcaaaca aaaaaatccg tatccgtttg
    60001 aaagcttacg aacaccgtac gcttgacaca gcggctgcaa aaatcgtaga atcagctact
    60061 cgtacaggtg cacaagttgc gggtccaatc ccacttccaa ctgaacgtag cctctacaca
    60121 atcattcgtg cgactcacaa atacaaagac tctcgcgaac aatttgaaat gcgtacacac
    60181 aaacgtttga tcgatatcgt taacccaact caaaaaacag ttgatgcctt gatgaaattg
    60241 gatcttccaa gtggtgtaaa cgtagaaatc aaactttaat ctaaaatata aaagagcaga
    60301 ggctggtgtt tcaatctaat tgaacacgga ctaaactcgg tgtgaaaaag ataaacttcc
    60361 tattgtccgt tagacactgc gttagtttcc tattttcacg ttgagtttga cgccctttgt
    60421 atcttagact tgagcataaa aaacgctcgt taaaaacttt ttgaataaaa aatatagaaa
    60481 aggaactatt ttctcatgac aaaaggaatc ttagggaaaa aagtgggaat gactcaaatc
    60541 ttcactgaag ctggcgaatt gatccctgta acagttattg aagcaactcc aaacgttgtt
    60601 cttcaagtta aaactgttga aacagacgga tacaacgcta tccaagttgg tttcgatgac
    60661 aaacgcgaag tattgagcaa caaacctgct aaaggacatg tagcgaaagc taacacggct
    60721 cctaagcgct tcattcgtga attcaaaaac gttgaaggct tggaagttgg cgctgaaatc
    60781 acagttgaaa cattcgcagc tggagatgtt gttgatgtaa ctggtacttc taaaggtaaa
    60841 ggtttccaag gtgttatcaa acgccacgga caatcacgtg gaccaatggc tcacggttct
    60901 cgttaccacc gtcgtccagg ttctatgggg cctgttgcac ctaaccgcgt attcaaaggt
    60961 aaaaaccttg caggacgtat gggtggcgac cgcgtaacaa ttcaaaacct tgaagttgta
    61021 caagttgttc cagaaaagaa cgttatcctt atcaaaggta acgtaccagg tgctaagaaa
    61081 tctcttatca ctatcaaatc agcagttaaa gctggtaaat aataaagaaa ggggaaatca
    61141 gtcacaatgg caaacgtaac attatttgac caaactggta aagaagctgg ccaagttgtt
    61201 cttaacgatg cagtatttgg tatcgaacca aatgaatcag ttgtgtttga tgtaatcatc
    61261 agccaacgcg caagccttcg tcaaggaaca cacgctgtta aaaaccgctc tgcagtatca
    61321 ggtggtggac gcaaaccatg gcgtcaaaaa ggaactggac gtgctcgtca aggttctatc
    61381 cgctcaccac aatggcgtgg tggtggtgtt gtcttcggac caactccacg ttcatacggc
    61441 tacaaacttc cacaaaaagt tcgtcgccta gctcttaaat cagtttactc tgaaaaagtt
    61501 gctgaaaaca aattcgtagc tgtagacgct ctttcattta cagctccaaa aactgctgaa
    61561 tttgcaaaag ttcttgcagc attgagcatc gattctaaag ttcttgttat ccttgaagaa
    61621 ggaaatgaat tcgcagctct ttcagctcgt aaccttccaa acgtgaaagt tgcaactgct
    61681 acaactgcaa gtgttcttga catcgcaaat agcgacaaac ttcttgtcac acaagcagct
    61741 atctctaaaa tcgaggaggt tcttgcataa tgaatttgta tgatgttatc aaaaaacctg
    61801 tcatcactga aagctcaatg gctcaacttg aagcagggaa atatgtattt gaagttgaca
    61861 ctcgtgcaca caaacttttg atcaagcaag ctgttgaagc tgctttcgaa ggtgttaaag
    61921 ttgccaatgt taacacaatc aacgtaaaac caaaagctaa acgtgttgga cgttacactg
    61981 gttttactaa caaaactaaa aaagctatca tcacacttac agctgattct aaagcaatcg
    62041 agttgtttgc tgctgaagct gaataatcta aggaggaaat atcgtgggaa ttcgtgttta
    62101 taaaccaaca acaaacggtc gccgtaatat gacttctttg gatttcgctg aaatcacaac
    62161 aagcactcct gaaaaatcat tgcttgttgc attgaagagc aaggctggtc gtaacaacaa
    62221 cggtcgtatc acagttcgtc accaaggtgg tggacacaaa cgtttctacc gtttggttga
    62281 cttcaaacgt aataaagaca acgttgaagc agttgttaaa acaatcgagt acgatccaaa
    62341 ccgttctgca aacatcgctc ttgtacacta cactgacggt gtgaaagcat acatcatcgc
    62401 tccaaaaggt cttgaagtag gtcaacgtat cgtttcaggt ccagaagcag atatcaaagt
    62461 cggaaacgct cttccacttg ctaacatccc agttggtact ttgattcaca acatcgagtt
    62521 gaaaccaggt cgtggtggtg aattggtacg tgctgctggt gcatctgctc aagtattggg
    62581 ttctgaaggt aaatatgttc ttgttcgtct tcaatcaggt gaagttcgta tgattcttgg
    62641 aacttgccgt gctacagttg gtgttgtcgg aaacgaacaa catggacttg taaaccttgg
    62701 taaagcagga cgtagccgtt ggaaaggtat ccgcccaaca gttcgtggtt ctgtaatgaa
    62761 ccctaacgat cacccacacg gtggtggtga aggtaaagca ccagttggtc gtaaagcacc
    62821 atctactcca tggggcaaac ctgctcttgg tcttaaaact cgtaacaaga aagcgaaatc
    62881 tgacaaactt atcgttcgtc gtcgcaacga gaaataatat taaactagtc gcttaagcaa
    62941 ctagtaaatc cgccagctcg gtagcgctcc ataggagtgc aagccgctgt ggtacaacat
    63001 ttaaaggaga aaatataaaa atgggacgca gtcttaaaaa aggacctttc gtcgatgagc
    63061 atttgatgaa aaaagttgaa gctcaagcta acgacgaaaa gaaaaaagtt attaaaactt
    63121 ggtcacgtcg ttcaacgatc ttcccaagtt tcattggtta cactattgca gtttatgacg
    63181 gacgtaaaca cgtacctgtt tacatccaag aagacatggt aggccacaaa cttggtgaat
    63241 ttgcaccaac tcgtacttac aaaggtcacg ctgcagacga caagaaaaca cgtagaaaat
    63301 aaggagaaca taaatggcag aaattacttc agctaaagca atggctcgta cagtacgtgt
    63361 ttcacctcgt aaatcacgtc ttgttcttga taacatccgt ggtaaaagcg tagccgatgc
    63421 aatcgcaatc ttgacattca ctccaaacaa agctgctgaa atcatcttga aagttttgaa
    63481 ctcagctgta gctaacgctg aaaacaactt tggtttggat aaagctaact tggtagtatc
    63541 tgaagcattc gcaaacgaag gaccaactat gaaacgtttc cgtccacgtg cgaaaggttc
    63601 agcttcacca atcaacaaac gtacagctca catcactgta gctgttgcag aaaaataagg
    63661 aggtaaaatc gtgggtcaaa aagtacatcc aattggtatg cgtgtcggca tcatccgtga
    63721 ttgggatgcc aaatggtatg ctgaaaaaga atacgcggat taccttcatg aagatcttgc
    63781 aatccgtaaa ttcgttcaaa aagaacttgc tgacgcagca gtttcaacta ttgaaatcga
    63841 acgcgcagta aacaaagtta acgtttcact tcacactgct aaaccaggta tggttatcgg
    63901 taaaggtggt gctaacgttg atgcactccg tgcaaaactt aacaaattga ctggaaaaca
    63961 agtacacatc aacatcatcg aaatcaaaca acctgatttg gatgctcacc ttgtaggtga
    64021 aggaattgct cgtcaattgg agcaacgtgt tgctttccgt cgtgcacaaa aacaagcaat
    64081 ccaacgtgca atgcgtgctg gagctaaagg aatcaaaact caagtatcag gtcgtttgaa
    64141 cggtgcagat atcgcccgtg ctgaaggata ctctgaagga actgttccgc ttcacacact
    64201 tcgtgcagat atcgattacg cttgggaaga agcagatact acatacggta aacttggtgt
    64261 taaagtatgg atctaccgtg gtgaagttct tccagctcgt aaaaacacta aaggaggtaa
    64321 ataaccaatg ttagtaccta aacgtgttaa acaccgtcgt gagttccgtg gaaaaatgcg
    64381 cggtgaagca aaaggtggaa aagaagtagc attcggtgaa tacggtcttc aagctacaac
    64441 tagccactgg atcactaacc gccaaatcga agctgctcgt atcgccatga ctcgttacat
    64501 gaaacgtggt ggtaaagttt ggattaaaat cttcccacac aaatcataca ctgctaaagc
    64561 tatcggtgtg cgtatgggat ctggtaaagg ggcacctgaa ggttgggtag caccagttaa
    64621 acgtggtaaa gtgatgttcg aaatcgctgg tgtatctgaa gagattgcac gtgaagcgct
    64681 tcgacttgct agccacaaat tgccagttaa atgtaaattc gtaaaacgtg aagcagaata
    64741 aggagaaggc atgaaactta atgaagtaaa agaatttgtt aaagaacttc gtggtctttc
    64801 tcaagaagaa ctcgcgaagc gcgaaaacga attgaaaaaa gaattgtttg aacttcgttt
    64861 ccaagctgct actggtcaat tggaacaaac agctcgcttg aaagaagtta aaaaacaaat
    64921 cgctcgtatc aaaacagttc aatctgaagc gaaataatag actagggaag gagaaatttc
    64981 aatggaacgc aataatcgta aagttcttgt tggacgtgtt gtatctgaca aaatggacaa
    65041 gacaatcaca gttgtagttg aaacaaaacg taaccaccca gtctatggta aacgtattaa
    65101 ctactctaaa aaatacaaag ctcatgatga aaacaatgtt gccaaagaag gcgatatcgt
    65161 acgtatcatg gaaactcgcc cgctttcagc tacaaaacgt ttccgtcttg tagaagttgt
    65221 tgaagaagcg gtcatcatct aatcaaacct gaaaggagaa aactgaaatg attcaaacag
    65281 aaactcgttt gaaagtcgca gacaacagcg gtgctcgcga aatcttgact atcaaagttc
    65341 ttggtggttc aggacgtaaa tttgcaaaca tcggtgatgt tatcgtggca tctgtaaaac
    65401 aagctactcc tggtggtgcg gttaaaaaag gtgacgttgt taaagcagtt atcgttcgta
    65461 ctaaatcagg tgctcgtcgt gctgatggtt catacatcaa atttgacgaa aacgcagcag
    65521 ttatcatccg tgaagacaaa actcctcgcg gaacacgtat ctttggccca gttgcacgtg
    65581 aattgcgtga aggtggcttc atgaagatcg tgtcacttgc tccagaagta ctttaatttt
    65641 taggaacaaa ctagtcccct agcttcaagc tagggtgccc ttatgggcgt aagaaaaatc
    65701 aaggagaaac ctaatgtttg taaaaaaagg cgacaaagtt cgcgtaatcg ctggtaaaga
    65761 taagggaaca gaagctgttg tccttactgc ccttccaaaa gtaaacaaag ttatcgttga
    65821 aggtgttaac attgttaaga aacaccaacg tccaactaac gagcttcctc aaggtggtat
    65881 catcgagaaa gaagcagcta tccacgtatc aaatgttcaa gttttggaca aaaatggtgt
    65941 agctggtcgt gttggttaca aatttgtaga cggtaaaaaa gttcgctaca acaaaaaatc
    66001 aggcgaagtg cttgattaat cacgaaggaa aggagaagta taatggcaaa tcgtttaaaa
    66061 gaaaaatatc ttaatgaagt agttcctgct ttgacagaac aattcaacta ctcatcagtg
    66121 atggctgtgc ctaaagtaga taagattgtt ttgaacatgg gtgttggtga agctgtatca
    66181 aacgctaaaa gccttgaaaa agctgctgaa gaattggcac ttatctcagg tcaaaaacca
    66241 cttatcacta aagctaaaaa atcaatcgcc ggcttccgtc ttcgtgaagg tgttgcgatc
    66301 ggtgcaaaag ttacccttcg tggtgaacgt atgtacgaat tcttggataa attggtatca
    66361 gtttcacttc cacgtgtacg tgacttccac ggtgttccaa caaaatcatt tgatggacgc
    66421 gggaactaca cacttggtgt gaaagaacaa ttaatcttcc cagaaatcaa cttcgatgac
    66481 gttgacaaaa ctcgtggtct tgacatcgtt atcgtaacaa ctgctaacac tgacgaagag
    66541 tcacgtgcat tgcttacagg ccttggaatg ccttttgcaa aataatatag gaggtaaatc
    66601 taatggctaa aaaatcaatg gtagctagag aggctaaacg ccaaaaaatt gttgaccgtt
    66661 atgctgaaaa acgtgctgca ttaaaggcgg caggggacta cgaaggttta tctaaattac
    66721 ctcgcaacgc ctcaccgact cgtttacata atcgttgtag agttacgggg cgcccacatt
    66781 cagtttaccg caaatttggt ctgagtcgta tcgcttttcg cgaacttgcg cataaaggtc
    66841 aaattcctgg tgtaacaaaa gcatcttggt aatttaagat atcaagagcg tcaaaactcc
    66901 aagtaaaaat aggaaacttg acgaagaaac taaagtttct aggaaagttt atctttttca
    66961 cacagagttt agcccgggtt caattgggct tgccaatttg aacacgagct acagctttgg
    67021 caaaaaagac caatttgctt tggagcattg cttctgcatt aaattgtcta tttttgctcg
    67081 tactgttacg ctctttgtat catgtattaa ctagcaagtg caacttgcaa actactagta
    67141 agaggagaaa aacaaaatgg ttatgactga cccaatcgca gacttcctaa ctcgtattcg
    67201 taatgctaac caagctaaac acgaagtact tgaagtacct gcatcaaaca tcaaaaaagg
    67261 gattgctgaa atccttaaac gcgaaggttt tgtaaaaaac gttgaaatca ttgaagatga
    67321 caaacaaggc gtcatccgtg tatttcttaa atacggacca aatggtgaga aagttatcac
    67381 taacttgaaa cgtgtttcta aaccaggact tcgtgtctac aaaaaacgtg aagaccttcc
    67441 aaaagttctt aacggacttg gaattgccat cctttcaact tctgaaggtt tgcttactga
    67501 taaagaagca cgccaaaaga atgttggtgg tgaggttatc gcttacgttt ggtaaaatca
    67561 agatacaaag ctcgtaaaga acaaagcaaa attaggaagt tggagaagtt tgtttacaaa
    67621 caagccaact tatctatttt gcacagttct tagagcgtgt tcagttcagc tcttgaacta
    67681 aataagtatc tgaaccccgt gaaaactggc cgttctggcc tgacaattta acaggagaaa
    67741 ataaacatgt cacgtattgg taataaagtt atcgtgttgc ctgctggtgt tgaactcgct
    67801 aacaatgaca acgttgtaac tgtaaaagga cctaaaggag aacttactcg tgagttctca
    67861 aaagatattg aaatccgtgt ggaaggtact gaaataactc ttcaccgtcc aaacgattca
    67921 aaagaaatga aaactatcca cggaactact cgtgcccttt tgaacaacat ggttgttggt
    67981 gtatcagaag gattcaagaa agaacttgaa atgcgtgggg ttggttaccg tgcacagctt
    68041 caaggatcta aacttgtttt ggctgttggt aaatctcatc cagacgaagt tgaagctcca
    68101 gaaggaatta cttttgaact tccaaaccca acaacaatcg ttgttagcgg aatttcaaaa
    68161 gaagtagttg gtcaaacagc tgcttacgta cgtagccttc gttcaccaga accatataaa
    68221 ggtaaaggta tccgttacgt tggtgaattc gttcgccgta aagaaggtaa aacaggtaaa
    68281 taatgttgag tggttgatca tcaaccacca acctattttc caactttgtg catagcacac
    68341 gatttaaaac taaagaggtg aaaactgtga tttcaaaacc agataaaaac aaactccgcc
    68401 aaaaacgcca ccgtcgcgtt cgcggaaaac tctctggaac tgctgatcgc ccacgtttga
    68461 acgtattccg ttctaataca ggcatctacg ctcaagtgat tgatgacgta gcgggtgtaa
    68521 cgctcgcaag tgcttcaact cttgataaag aagtttcaaa aggaactaaa actgaacaag
    68581 ccgttgctgt cggtaaactc gttgcagaac gtgcaaacgc taaaggtatt tcagaagtgg
    68641 tgttcgaccg cggtggatat ctatatcacg gacgtgtgaa agctttggct gatgcagctc
    68701 gtgaaaacgg attgaaattc taataggagg acactagaaa atggcattta aagacaatgc
    68761 agttgaatta gaagaacgcg tagttgctgt caaccgtgtt acaaaagttg ttaaaggtgg
    68821 acgtcgtctt cgtttcgcag ctcttgttgt tgttggtgac cacaatggtc gcgtaggatt
    68881 tggtactggt aaagctcaag aagttccaga agcaatccgt aaagcagtag atgatgctaa
    68941 gaaaaacttg atcgaagttc ctatggttgg aacaacaatc ccacacgaag ttctttcaga
    69001 attcggtgga gctaaagtat tgttgaaacc tgctgtagaa ggttctggag ttgccgctgg
    69061 tggtgcagtt cgtgccgttg tggaattggc aggtgtggca gatattacat ctaaatcact
    69121 tggttctaac actccaatca acattgttcg tgcaactgtt gaaggtttga aacaattgaa
    69181 acgcgctgaa gaaattgctg cccttcgtgg tatttcagtt tctgatttgg cataagaaag
    69241 gggataaaat ggctcaaatt aaaattactt tgactaagtc tccaatcgga cgcattccat
    69301 cacaacgtaa aactgttgta gcacttggac ttggcaaatt gaacagctct gttattaaag
    69361 aagataacgc tgctatccgt ggtatgatca cagcagtatc tcacttagta acagttgaag
    69421 aagtaaacta atgaagtttt aggggatgtg cactgtacca tcccctaaaa ctagatatag
    69481 tcatctatga tgacatcgta taggcgagtt gatgggggag acaacctttt ctcccttatc
    69541 ggcgctagca ttttacaaaa gaggagaaaa taaaaatgaa acttcatgaa ttgaaacctg
    69601 cagaaggttc tcgtaaagta cgtaaccgcg ttggtcgtgg tacttcatca ggtaacggta
    69661 aaacatctgg tcgtggtcaa aaaggtcaaa aagctcgtag cggtggcgga gttcgccttg
    69721 gttttgaagg tggacaaact ccattgttcc gtcgtcttcc aaaacgtgga ttcactaaca
    69781 tcaacgctaa agaatacgca attgtgaacc ttgaccaatt gaacgtcttt gaagatggtg
    69841 ctgaagtaac tccagttgtt cttatcgaag caggaattgt taaagctgaa aagtcaggta
    69901 ttaaaattct tggtaacggt gagttgacta agaaattgac tgtgaaagca gctaaattct
    69961 ctaaatcagc tgaagaagct atcactgcta aaggtggttc agtagaagtc atctaagaga
    70021 ggtgacctat gttttttaaa ttattaagag aagctcttaa agtcaagcag gttcgatcaa
    70081 aaattttatt tacaattttt atcgttttgg tctttcgtat cggaactagc attacagttc
    70141 ctggtgtgaa tgccaatagc ttgaatgctt taagtggatt atccttctta aacatgttga
    70201 gcttggtgtc ggggaatgcc ctaaaaaact tttcgatttt tgccttagga gttagtccct
    70261 atatcaccgc ttctattgtt gtccaactct tgcaaatgga tattttaccc aagtttgtag
    70321 agtggggtaa acaaggggaa gtaggtcgaa gaaaattgaa tcaagctact cgttatattg
    70381 ctctagttct cgcttttgtg caatctatcg ggattacagc tggttttaat accttggctg
    70441 gagctcaatt gattaaaact gctttaactc cacaagtttt tctgacgatt ggtatcatct
    70501 taacagctgg tagtatgatt gtcacttggt tgggtgagca aattacagat aagggatacg
    70561 gaaacggtgt ttccatgatt atctttgccg ggattgtttc ttcaattcca gagatgattc
    70621 agggcatcta tgtggactac tttgtgaacg tcccaagtag ccgtatcact tcatctatca
    70681 ttttcgtaat cattttgatt attactgtat tgttgattat ttactttaca acttatgttc
    70741 aacaagcaga atacaaaatt ccaatccaat atactaaggt tgcacaaggt gctccatcta
    70801 gctcttacct tccgttaaag gtaaatcctg ctggagttat ccctgttatc tttgccagtt
    70861 cgattactgc agcgcctgcg gctattcttc agtttttgag tgccacaggt catgattggg
    70921 cttgggtaag ggtagcacaa gagatgttgg caactacttc tccaactggt attgccatgt
    70981 atgctttgtt gattattctc tttacattct tctatacgtt tgtacagatt aatcctgaaa
    71041 aagcagcaga gagcctacaa aagagtggtg cctatatcca tggagttcgt cctggtaaag
    71101 gtacagaaga atatatgtct aaacttcttc gtcgtcttgc aactgttggt tccctcttcc
    71161 ttggtgtgat ttccatttta ccgattgcag ctaaagatgt atttggtctt tctgatgttg
    71221 ttgcctttgg tggaacaagt ctcttgatca ttatctctac aggtatcgaa ggaatcaagc
    71281 aattggaagg ttacctattg aaacgtaagt atgttggttt catggacaga acagaataaa
    71341 agtatttact gaatcagtaa atactgaggg agtggaggtt taaactctga catttgtaag
    71401 agttggatct cccctcttct attttgtttt taaatagggg tgaaaagact ttttgcttct
    71461 atttaaaaat aaaataagga gatcaaatca tgaatctttt gattatgggc ttacctggtg
    71521 caggtaaggg aactcaagca gcaaaaatcg tagaacaatt ccatgttgca catatctcaa
    71581 caggtgatat gttccgcgct gcaatggcaa atcaaactga aatgggtgtt cttgctaagt
    71641 catatattga caagggtgaa ttggttcctg acgaagttac aaatggaatc gtaaaagaac
    71701 gcctttcaca agatgatatt aaagaaacag gattcttatt ggatggttac ccacgtacaa
    71761 ttgaacaagc tcatgccttg gacaaaacat tggctgaact tggcattgaa ctagaaggta
    71821 ttatcaatat tgaagtgaac cctgacagcc tcttggaacg tttgagtggc cgtatcatcc
    71881 actgcgtaac tggagaaact ttccacaagg tctttaaccc accagttgac tataaagaag
    71941 aagattacta ccaacgtgaa gatgataagc ctgagacagt aaaacgtcgt ttggatgtta
    72001 atattgctca aggagaacca atcattgctc actaccgtgc caaaggtttg gttcatgaca
    72061 tcgaaggtaa tcaagatatc aatgatgtct tctcagatat tgaaaaagta ttgacaaatt
    72121 tgaaataaag cgtttttcac acttgcaaaa atccgctaca aatgttatac tgagatagtc
    72181 tgacttataa ttgttgtctc tgtgtctaga ggcatcgaat cgaaatttat ggaggtgctt
    72241 ttgcgtggca aaagacgatg tgattgaagt tgaaggcaaa gtagttgata caatgccgaa
    72301 tgcaatgttt acggttgaac ttgaaaatgg acatcagatt ttagcaacag tttctggtaa
    72361 aattcgtaaa aactatattc gtattttagc gggagatcgt gttactgtcg aaatgagtcc
    72421 atatgacttg acacgtggac gtatcactta ccgctttaaa taatcgaaaa acttggaggg
    72481 ataagaaatg aaagtaagac catcggtcaa accaatttgc gaatactgta aagttattcg
    72541 tcgtaatggt cgtgttatgg taatttgccc agcaaatcca aaacacaaac aacgtcaagg
    72601 ataagataga aaggagaaaa catggctcgt attgctggag ttgatattcc aaatgacaaa
    72661 cgcgtagtaa tctcattgac ttatgtttat ggtatcggac ttgcaacatc taagaaaatt
    72721 ttggctgctg ctggaatctc agaagatgtt cgtgtacgtg atcttacatc agatcaagaa
    72781 gatgctatcc gtcgtgaagt ggatgcaatc aaagttgaag gtgaccttcg tcgtgaagta
    72841 aacttgaaca tcaaacgttt gatggaaatc ggttcatacc ttggtatccg tcaccgtcgt
    72901 ggacttcctg tccgtggaca aaatactaaa aacaacgctc gcactcgtaa aggtaaagct
    72961 gttgcgattg ctggtaagaa aaaataatat aggaggtaaa agtcttggct aaaccaacac
    73021 gtaaacgtcg tgtgaaaaag aatatcgaat ctggtattgc tcatattcac gctacattta
    73081 ataacactat tgttatgatt actgatgtgc atggtaatgc aattgcttgg tcatcagctg
    73141 gtgctcttgg tttcaaaggt tctcgtaaat ctacaccatt cgctgctcaa atggcttctg
    73201 aagctgctgc taaatctgca caagaacacg gtcttaaatc agttgaagtt actgtaaaag
    73261 gtccaggttc tggtcgtgag tcagctattc gtgcgcttgc tgccgctggt cttgaagtaa
    73321 cagcaattcg tgatgtgact ccagtgccac acaatggtgc tcgtcctcca aaacgtcgcc
    73381 gtgtataatc atcgcattac actgcttttc gtttaagagg gagtaactaa atgatcgagt
    73441 ttgaaaaacc aaatataaca aaaattgatg aaaataaaga ttatggcaag tttgtaatcg
    73501 aaccacttga acgtggctac ggtacaactc ttggtaactc tcttcgtcgt gtacttctag
    73561 cttctctacc aggagcagct gtgacatcta tcaacattga tggtgtgtta catgagtttg
    73621 acacagttcc aggtgttcgt gaagacgtga tgcaaatcat tctgaacatt aaaggaattg
    73681 cagtgaaatc gtacgttgaa gacgaaaaaa tcatcgaact ggatgttgaa ggtcctgctg
    73741 aagtaacagc tggtgacatt ttgacagata gcgatattga aattgtaaat ccagatcatt
    73801 atctctttac aatcggtgaa ggttcttctc taaaagcgac tatgactgtt aacagtggtc
    73861 gtggatatgt acctgctgat gaaaataaaa aggataatgc accagttgga acacttgctg
    73921 tagattctat ttatacacca gttacaaaag tcaactatca agtggaacct gctcgtgtag
    73981 gtagcaatga tggtttcgac aaattaaccc ttgaaatctt gacaaatgga acaattattc
    74041 cagaagatgc tttagggctt tcagcacgta ttttgacaga acatcttgat ttgtttacaa
    74101 atcttactga gattgctaag tcaactgaag tgatgaaaga agctgatact gaatctgacg
    74161 accgtatttt agatcgtacg attgaggaac tggacttgtc tgtgcgttca tacaactgtt
    74221 taaaacgtgc cggtatcaat actgtgcatg atttgacaga aaaatctgaa gcagagatga
    74281 tgaaagtacg aaatcttgga cgcaagagtt tggaagaagt gaaactcaaa ctcattgatt
    74341 tgggtcttgg attaaaagat aaataaagga ggaatacatg gcttaccgta aactaggacg
    74401 cactagctca caacgtaaag caatgcttcg cgatttgaca actgaccttt tgatcaacga
    74461 atcaatcgtg acaactgaag ctcgtgctaa agaaatccgt aaaactgttg aaaaaatgat
    74521 tactctaggt aaacgtggtg atttgcatgc acgtcgtcaa gcagctgctt tcgtacgtaa
    74581 tgaaatcgca tctgaaaact atgatgaagc aactgataag tacacttcta ctacagcact
    74641 tcaaaaattg ttctcagaaa tcgcacctcg ttatgctgaa cgtaacggtg gatacactcg
    74701 tatccttaaa actgaaccac gtcgtggtga tgcagcgcca atggcgatca tcgaattagt
    74761 ataaaatcat caattttgtt gagtgttatg atgatggagt cttgtgctct tagtctagct
    74821 ctggtctacc gctaggattt cggtcctagc gggaacactc atcataagtt gggatagtag
    74881 acgcttgttt acgaaattgt ttttttctta agaacaactt cgtaagcagg cgtttttgag
    74941 tattttcgtt agaattatgc tatactattt gaaaagaatc ctgtttaatg ttaaggtttc
    75001 ttattttaag aagaattgga gtttacttat gaaagcgatt ataactgttg ttggtaaaga
    75061 taaatctgga attgttgcag gtgtttctgg taaaattgca gaattaggat tgaatattga
    75121 cgatatctct caaactgtat tggatgaata ttttacgatg atggctgttg tatctagtga
    75181 tgaaaagcaa gattttacct atcttcgtaa tgaatttgaa gcttttgggc aaactttgaa
    75241 tgtaaaaatc aatattcaga gtgcagcgat tttcgaagct atgtataata tctaggaggt
    75301 catcatggat attagacaag ttactgaaac catcgccatg attgaggagc aaaacttcga
    75361 tattagaacc attaccatgg ggatttctct tttggactgt atcgatccaa atatcaatcg
    75421 tgctgcggag aaaatctatc aaaaaattac gacaaaggcg gctaatttag tagctgttgg
    75481 tgatgaaatt gcggctgagt tgggaattcc tatcgttaat aagcgtgtat cggtgacacc
    75541 tatttctctg attggggcag cgacagatgc gacggactac gtggttctgg caaaagcgct
    75601 tgataaggct gcgaaagaga ttggtgtgga ctttattggt ggtttttctg ccttagtaca
    75661 aaaaggttat caaaagggag atgagattct catcaattcc attcctcgcg ctttggctga
    75721 gacggataag gtctgctcgt cagtcaatat cggctcaacc aagtctggta ttaatatgac
    75781 ggctgtggca gatatgggac gaattatcaa ggaaacagca aatctttcag atatgggagt
    75841 ggccaagttg gttgtattcg ctaatgctgt tgaggacaat ccatttatgg cgggtgcctt
    75901 tcatggtgtt ggggaagcag atgttatcat caatgtcgga gtttctggtc ctggtgttgt
    75961 gaaacgtgct ttggaaaaag ttcgtggaca gagctttgat gtagtagccg aaacagttaa
    76021 gaaaactgcc tttaaaatca ctcgtatcgg tcaattggtt ggtcaaatgg ccagtgagag
    76081 actgggtgtg gagtttggta ttgtggactt gagtttggca ccaacccctg cggttggaga
    76141 ctctgtggca cgtgtccttg aggaaatggg gctagaaaca gttggcacgc atggaacgac
    76201 agctgccttg gccctcttga acgaccaagt taaaaagggt ggagtgatgg cctgcaacca
    76261 ggtcggtggt ctatctggtg cctttatccc tgtttctgag gatgaaggaa tgattgctgc
    76321 agtgcaaaat ggctctctta atttagaaaa actagaagct atgacggcta tctgttctgt
    76381 tggattggat atgattgcca tcccagaaga tacgcctgct gaaactattg cggctatgat
    76441 tgcggatgaa gcagcaatcg gtgttatcaa catgaaaaca acagctgttc gtatcattcc
    76501 caaaggaaga gaaggcgata tgattgagtt tggtggtcta ttaggaactg cacccgttat
    76561 gaaggttaat ggggcttcgt ctgtcgactt catctctcgc ggtggacaaa tcccagcacc
    76621 aattcatagt tttaaaaatt aagaaaatag gagaaatttt aagttctatt taagattaga
    76681 tgtgtatact ataatcatta aataaagacc tcctaatatt atttgaaaca gataacactg
    76741 aattagtttg aatttgattt tcatctaata tctttattta atgaactcct aaactttttc
    76801 ataataatct ccttcaaaag tcgcctgtat gggtggcttt tattttatca ttcatgatat
    76861 aatagaagca aacggaggac ggaaaatggt aaaagtacga ttgtatttgg tacgtcatgg
    76921 caagaccatg tttaacacga ttggtcgcgc gcaaggttgg agcgatactc ccttaactgc
    76981 tgaaggtgaa cgagggattc aagagttagg aatcggtttg cgagaatctg atctacagtt
    77041 tgagcgcgct tattcgagtg attctggtcg taccattcag accatgggaa ttatccttga
    77101 agaacttggc ttgcagggga aaatccctta tcgcatggac aagcgtatca gagaatggtg
    77161 tttcggtagt tttgatggag cctatgatgg cgatcttttc atgggcatta ttcctcgtat
    77221 ctttaatgtg gaccacgttc accaattgtc ttatgctgaa ctggctgagg gcttggtaga
    77281 ggtcgataca gctggttggg ctgaaggctg ggaaaaactc agtggccgaa tcaaggaagg
    77341 ctttgaaatg attgcaaaag aaatggaaga tcaaggtgga ggtaacgccc ttgttgtcag
    77401 ccatggaatg actattggaa ccattgttta tctgattaat ggcatgcatc cgcatggtct
    77461 agataatggt agcgtgacga ttcttgaata tgaggacggt cagtttaggg ttgaagttgt
    77521 cggtgaccgt agttaccgag agctaggacg tgagaagatg gaagaaggct ctatttaatc
    77581 agtctagact tgcttgccat gagctaggga tttgataaga atatcaagat aagaaaaaac
    77641 agccgagggt actcctttcg gctgtttttg atgtggaaaa ctaaagtgta atgctattgc
    77701 ttttagagat tttcataaac aagagcaagg aacctactgt tagaacagtc aggatagttg
    77761 acaaggctgc ggctacaccg taatttcctc tgagaacctc tgtataaata gctacagtca
    77821 ttgttcttgt tttgacattg tagaggagga tagaagtaga gagttttgaa atcattgtga
    77881 cccaagataa gatggctcca gaaatgatac cagatagcat cattggagtt gtaatcttag
    77941 caaaggtatt gagacgacta cttcctaagc tttcagcagc ttcttcaata cttggtgcta
    78001 tttgttgtaa gctagcaaca gatgagcgaa tagtatacgg taatcttctg acagatagag
    78061 acataatcaa gatgaaagca gtccctgtaa tcataagaaa tccacttcca aatagaccag
    78121 agaaatgaag gcaatcccta gaacggttcc tggtacaata taaggtacca tactgaggct
    78181 gtcaattaag tttgtaaaca aattccgttt tctaacggct aggtaggaga taaatgtcgc
    78241 aaatagaaca actagaacta aggcaatcaa agggatacga atggtattga aaatagcaga
    78301 tcccatacga ttgaaagcta ccttgtaact gtttggagaa taacctttaa caaataccat
    78361 acctgatgtt tttaggaaag aggtataaat taagtagatt tgaggtaaaa cagagataaa
    78421 gataattccg tagactgttg cataaatggc agccattttt ccttttgtag tttttttagg
    78481 ctcaattgga tggagcagat tcatgctgaa actgtagcgg tttgcaatgt gtttttggat
    78541 aaggaaaatt gccaaggcaa tgataatcgc cataattgca aaagcagaat ttcctccaac
    78601 ctcgctaata aattgggtat aaatcaggac agggaaagtc cgatatcctt cgccaatcaa
    78661 cataggcgtt ccaaagtctg agaatgctct cataaataca agcaaggagc tgctagtaag
    78721 gttggaacta ggagaggtaa aacaaccgtt acgataggtt taaatccgaa ggaccccatg
    78781 ctttcagctg cttcaagtag agaattgtca atactgttca ttgttccagc aacatataga
    78841 aataccagtg ggaatagttg cagtgtaaag acaagtacaa ttcctttgaa tccataaata
    78901 tcgatagctg gaagatgaag ggcatttgtc aaaaatttag tgatgacccc atttcgtcct
    78961 agcaagagaa cccaggagta ggctcctacg aaaggagctg acatggaagc aatgataatc
    79021 aatatttgta gaaatttctt ccccttgaag tcatacatag agaagagata agctaatagg
    79081 gttcctacaa ctaaggaagt gacagtagcg gtaatggaaa ccttgaaact gttgactagt
    79141 gtctcagagt agtagacttt actaaagaaa gtgacaaaat tagctagtga gaattgtcct
    79201 tcatgtataa gtgcttgctt gagcacggta acgataggat aaacgagaaa gacaagatag
    79261 gtaagaaaga tgaagaaaga ggaggttgtc caaatattta gttttttaca ttccatggtt
    79321 gactcctttt atcaggtttt gggaaccatc tgcagaaaag atgtttaatt tttgcgtatt
    79381 gattcgtaga cgaatacgat tgcctttttg tagttcttct tcaaaagttg attcttcact
    79441 aacttgaatt tttgaggcaa aacctgtctc aatgaaatac tccgtattta gtccaagata
    79501 gacgctatcg ctaatagttc cttcaatatc tccagattca tctttgataa actcttcggg
    79561 acgaatgctt acatgaatag cttgctcctc aacctgatca agagctggca ttcgaagggc
    79621 atagccatct gaaaagacga tataagcgcc gtcgctccgt ttttcaagat tagtagggat
    79681 aatatttgtg catccgataa aggttgccac aaactcatta gctggtttat gatagagttc
    79741 ttttggtcgg ccgatttgtt ggatcacccc atctttcata gcagcaattt ggtctgaaat
    79801 agccatggct tcttcttggt cgtgggttac ataaacagtt gtaattccca cttcgtgttg
    79861 gattgctcgg atggcttgac gcatatccaa gcgaagtttg gcctccagat tactaagtgg
    79921 ctcgtccatg aggagaacac ttggattaac cgctaaggcg catgccaagg tgacacgttg
    79981 ttgttgtcca ccactgagtt tatcgggctt tcaatccgca tattgagcaa tttgcatgag
    80041 ttcaagatac ttgttggtct gttgaatcaa ttcttctttt ggaaccttct tttgcataag
    80101 accaaaagca acgttgtctc ggacagtcaa atgtgggaaa atagcgtagt tttggaaaac
    80161 cagcccgata ttgcgtttgc tgggttccat attattgatt tttgtatcat cgaagtaaaa
    80221 ttctccatct ttgatactgt tgaaacctgc aatcatacga agaagggtcg ttttcccaca
    80281 tcctgaagct ccaagaaggg taaagagact tccttttgga attgtaatgt tcaaattctc
    80341 aataacaggg acatcgtggt agattttttt ggcgttaata atttcgatct cactcatagt
    80401 gaacctcttt tactgtttag attggatatc tgtaaagact tcgttgtatt tcttaacgat
    80461 atctgattta ttcttgatga cataatcata atcttcagtg agtgttttga ttttgtcaat
    80521 tggtttcatg ttttcgcttg ttttagcatt tttacgaaca ggacggttag tagtggttgt
    80581 accaagtgta tcttgtactt cttgagagat aataaaatcg ataaatttct tggcattttc
    80641 catattttta gcttttttaa cgatagcagc actagcaggt aggaagacgg ttccttcttt
    80701 tggatagact actttaatgt tagctccgtc atttaagagt ttaactgctg gatcctcata
    80761 agagagacca acagccattt ctccatcaac gactgcttta tagacaccag atgaacttaa
    80821 accgatttta tagtgtattg aaactagaat agtacacctc tacttctaaa acattgttag
    80881 aaatcgattt gactgtcctg attaatttgt cctgttctta tttcatttta ctataccatc
    80941 aataagtgtg aaaagatctt ttacataaga ccaagcctta tcatctttgt aaccaccttg
    81001 agcttgtagc atatttgtta attgagcaaa ggcgctagaa gagtttgctg ggtcagcagt
    81061 tgcgattttt ccttttagtt caggtttgag aaggtcgcta tatccttcga tgttcatgcc
    81121 tttagttaaa tcagggtgga cgattaaaac actaccatct agtgtataag gagtagagaa
    81181 gccagttgtg ttttgatatt ctttgataac attatcattt tcttttgaaa tatagttttc
    81241 aaagagttct ccgtgggtag catattgtgt ataagaacca ccaaagataa catcagctac
    81301 aggaacttct ttttctgact ctagtttttt gaaaagttct ccagtaccag cttgaatcag
    81361 ttctattttg ataccatatt tttcttcaaa ggcaggaata gttgctccaa ttaagccttc
    81421 tgagtttggt caataaacga ctagcgaacc accgtctcct ttatcagatg aactgtcatc
    81481 ggcagattca ttagaagaac aagcagcata atacatccat ttctttttca tgatggatac
    81541 ctccgttgtg ttatttaagt ttattttaaa acaatgtaag cgtttttaaa acctacaatt
    81601 ctattctata gtgtattgaa tctataacag tacactttga ctgctaaaat atttctataa
    81661 attaatttga ctttcctgat agagatgttc acatcttatt tcaattcact atattagagt
    81721 aaaattctct acaaaaagaa gaatagccta ttttactatt cttccgagta atttcaattc
    81781 ctttggggaa atatggagat gctttttaaa tactttggca aaatatttat agtctgaaaa
    81841 tccaacttgg tcagagatag cgcttaaagg ggagttggga gattcagcca tcttatctat
    81901 agcttgtttc aggcgatatt gtaagatata ttcatttaga gtcatctttg ataaccttat
    81961 atagatagct ttcgttatag tttaaagctt cagcaatagt aatgctctgc atagtgcttg
    82021 tggacaaagg agataatttg ttgaatgatt tggttttgtg tatcaacctg ttggatagag
    82081 gtgagtaaag tttgatattc ttctaaaaaa ggagtttctt gagatgtgct aatttgtaat
    82141 cgcaaaacaa ttttttgaag acattctgtc aattccttgg tatcaattgg cttggataag
    82201 aaatcaactg ctccatattg catggctttt tggcattttg aaaatcgtta taacctgata
    82261 agataacttt ttcataagaa agagtacgag tggctttgaa catcataaaa gcatccataa
    82321 ttggcattgt gatgtctgtt aagacaaata tgagtttctt tttcttggat gagtttcatt
    82381 ccttcttgac cgtgactggc agttcctacg acttggatgc ctaaggcaga gtagtctacg
    82441 gcaatctcta gccattttcg gatgaggtgt tcatcttcta caataatgag cttaaacatg
    82501 agttagtctt tcgttacaaa tttgacccaa gtttctcctt ggcgattgac tcctaaatct
    82561 agctggacat cagaaaagaa attgctcaat tgtttgtagc tgttcatgat gccatgctgg
    82621 gtatgagggc tttctaaaga gtctaaaata gcgaatcgct cttgtttggt gagtcctcca
    82681 gcattatcct tgactaaaaa agttagagaa tctgcttcca aggtaatgtg gatatcaata
    82741 tgaagatcaa tacggtattg catcccatgt tttatagcat tttctactag aggaagcaag
    82801 aaaagtttag ggataggctg attatcgaca gtttctgggc agacaatatc ataggaaaag
    82861 tgctcgaaac gaatcttatg aatcataagg taatcctcta taatctttaa atcctgacaa
    82921 atggttgttt ctttttctaa atcggtgata ctgtatcgga gaatgcgcgt gaggtcacaa
    82981 aggctgcgat agagcttcta tggagaattt ctttttggag agatttttta aaggaatgag
    83041 acatccgcta cctcattgga aggttttttt gtgataagta tagcagttta aaaattctag
    83101 agcaaggtaa aatagaaaag gtttggctaa aattttttag ctaaaccttt tgaaaagtta
    83161 agtatgtatt atagatgctt gttatctgca aatagctaga gcatttcaag gaaatgaact
    83221 agaaataaca attaatatgg tggttcagaa ataccttttg ataatcaata agatcttcag
    83281 gatgaagtgc gttgattcca tccatttcat atttccgatt taataaacga tatttgtttt
    83341 caccaaattg atgaaaaggg agtagttgaa cttggtcgat atttaatgag ttaaatagag
    83401 tagcgaattt ttctgcatcc tctaaactat tgttaaaatt aggaataact gggattctta
    83461 aaacgatagt tttattttga gaaaaagcat aatgaatgtt tttaataatc atttgattaa
    83521 aaaccccagt cactttttta tgttttatag agttataatg ttttaggtct gtgtagataa
    83581 aatccacata ttgaattaaa tcgataaatt tttcatgatc aacaaaggca gtagtttcaa
    83641 tggcagtgtg tatgtgatgt tctttagctg attttaagat ggctttagca aattcaaact
    83701 gagcaaatat ttcacctcct gataaagtta aacctccacc ggattcttcg taaaattctt
    83761 tgtcttttaa tacctctgta ataatttctt ctacagtctt ttcttcaccg actaaggtga
    83821 atttctctcg ttgagcatct ttcatttttt caggtttcat tctttgagat tcaggattag
    83881 aacaccatgg acagcgcaga ggacatcctt ttaaaaaaac agttgtacga atacccgggc
    83941 cgtcatgaat tgaaaagtgt tgaatattaa aaataattcc tttagatatt tccataagag
    84001 ttcctcctct tcataagtct atcctatcac aaaaacgaaa gaaaaacaat tacgaacgaa
    84061 aggttaattt gttgtttttt gctttttatt ttggtagaat aaaacggagg tgtaaaatga
    84121 aaagattgga acaaattatt aaattagtat cagaatatga aaagatcgac gttaatacat
    84181 tatcggaaaa attaaatgta tcgaaagtaa cgattagaaa agatttagat aaattagagt
    84241 caaaaggttt attacacaga gagcatggat atgctgtatt aaatagtgga gatgacttaa
    84301 atgtacgttt gtcaattaac tatgaaatta agagaaaaat tgttcaggaa gcagtaaaat
    84361 tggtgtcaga taatgaaaca ataatgatag aatctggatc gacctgtgct ttacttgctg
    84421 aggaaatttg caagcaaaaa agaaatgtta cgattgtaac aaattcattt tttatagcaa
    84481 attttgtgag agcttatgat tcatgtcgta ttattgttct tggtggagag tttcagaagg
    84541 attcacaggt tactgtggga cctttattaa aagaaatgat acagactttt catgtgcatc
    84601 aagcttttgt tgggacagat ggttacgata aagagatggg ctttacagga aaagatttaa
    84661 tgcgcagtga ggtagttcaa tatatttcag cagcgtcgga taaagtcatt gtactaactg
    84721 actcaagtaa atttgataaa aggggtacag taagaagatt tgctttaagt caagtctatg
    84781 aagtaataac agacgaaaaa ctttctaaac aaaatatagc tacattagaa aatgctggga
    84841 taatggttaa ggtagtttcg taagaggtta aatgtatgaa tcaagatagg aataaactgc
    84901 tctctaaaat tgcttatctg tattatattg aaaacttaaa tcagtcacaa atagcagcaa
    84961 aattaggaat ttatagaacc tctattagta gaatgttaac agaagcaagg aatgcaggaa
    85021 ttgttaaaat tgaaatagag aattttgata ccaatatgtt taagttggaa aattatgtaa
    85081 aagaaaaata tggtctggaa agtttagaaa ttattccaaa tgaatttgat gataatccaa
    85141 caattttatc tgaaagaatt tctcaagttg cagcaggtgt ccttaggaat ctaattgatg
    85201 ataatatgaa aattggcttt tcttggggga aaagtttaag taatttagta gatttaattc
    85261 acagtaaaag tgtccgaaat gttcacttct atcctctagc aggtggtcct agtcacatac
    85321 acgctaaata ccatgtgaat acactgattt atgaaatgtc tagaaaattt catggagagt
    85381 gtacatttat gaatgcaacg attgtgcaag aaaataaatt gttagcagat ggtattttgc
    85441 aatcaagata ttttgaaaat ttgaaaaata gttggaaaga tttagatata gctgtagtcg
    85501 gaattggtga ttttagcaat aaaggaaagc atcaatggtt agacatgctt acagaggatg
    85561 actttaaaga attgaccaaa gttaaaactg taggagaaat ttgttgtcga ttttttgatt
    85621 caaaaggtaa agaagtctat gaaaacttac aggaaagaac gatagcaatc tctttggaag
    85681 atttaaaaaa tattcctcaa agtttagctg ttgcttacgg tgatacgaaa gtatcttcga
    85741 ttctttctgt cttgcgtgct aatttagtaa atcatttgat tacagacaaa aatacaattt
    85801 taaaagtttt ggaagaagat ggggatttga cttttagaga gattctaggt gagtgaaaat
    85861 gatagactga ttcagtttat cgtttttctt tttagttgat tgcacatttg tgcttatata
    85921 aacaaaaata gtttatctgt tgttttt
//
LOCUS       DAVLXH010000002        79374 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00028199
            SAMN33607166-rid17955573.denovo.002, whole genome shotgun sequence.
ACCESSION   DAVLXH010000002 DAVLXH010000000
VERSION     DAVLXH010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607166
            Sequence Read Archive: SRR23725544
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 79374)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 79374)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721421.1
            Genome Coverage       :: 115x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:42:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,210
            CDSs (total)                      :: 2,161
            Genes (coding)                    :: 2,023
            CDSs (with protein)               :: 2,023
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 73 of 138
            Pseudo Genes (incomplete)         :: 60 of 138
            Pseudo Genes (internal stop)      :: 40 of 138
            Pseudo Genes (multiple problems)  :: 31 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..79374
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607166-rid17955573.denovo.002"
                     /strain="AUSMDU00028199"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1349"
     gene            complement(193..1161)
                     /locus_tag="VYO11_000109"
     CDS             complement(193..1161)
                     /locus_tag="VYO11_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000081018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEV1594740.1"
                     /translation="MSQLYDITIVGGGPVGLFAAFYAHLRQAKVQIIDSLPQLGGQPA
                     ILYPEKEILDVPGFPNLTGEELTNRLIEQLNGFDTPIHLNETVLEIDKQEEEFAITTS
                     KGSHLTKTVIIAMGGGAFKPRPLELEGVEGYENIHYHVSNIQQYAGKKVTILGGGDSA
                     VDWALAFEKIAPTTLVHRRDNFRALEHSVQALQESSVTIKTPFAPSQLLGNGKTLDKL
                     EITKVKSDETETIDLDHLFVNYGFKSSVGNLKNWGLDLNRHKIIVNSKQESSQAGIYA
                     IGDCCYYDGKIDLIATGLGEAPTAVNNAINYIDPEQKVQPKHSTSL"
     gene            1297..2154
                     /locus_tag="VYO11_000110"
     CDS             1297..2154
                     /locus_tag="VYO11_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001867651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HEV1594741.1"
                     /translation="MNFQQLSNLQYWTSLFASPWTIAINLIDILIVAYILYHFTKAIA
                     GTKIMILVRGVLVFILAQILANMIGLTTISWLINQIITYGVIAAVVIFSPEIRTGLER
                     LGRATDFFSNAPISAEEQMIRAFVKSVEYMSPRKIGALVAIQRVRTLQEYISTGIPLD
                     AKISAELLINIFIPNTPLHDGAVIIKEERIAVTSAYLPLTKNTGISKEFGTRHRAAIG
                     LSEVSDALTFVVSEETGGISITYNGRFKHNLTLDEFETELREILLPKEEVGLSFKERL
                     LGGWKHEKK"
     gene            2141..2920
                     /locus_tag="VYO11_000111"
     CDS             2141..2920
                     /locus_tag="VYO11_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbbR-like domain-containing protein"
                     /protein_id="HEV1594742.1"
                     /translation="MKKNSLYIISSLFFACVLFVYATATNFQNSTSARQVKTETYTNT
                     VTNVPIDIRYNSDKYFISGFASEVSVVLTGANRLSLASEMQESTRKFKVTADLTDAGV
                     GTIEVPLSIEDLPNGLTAVATPQKITVKIGKKAQKDKVKIVPEIDPSQIDSRVQIENV
                     MVSDKEVSITSDQETLDRIDKIIAVLPTSERITGNYSGSVPLQAIDRNGVVLPAVITP
                     FDTIMKVTTKPVAPSSSTSNSSTSSSSETSSSTKATSSKTN"
     gene            2944..4296
                     /locus_tag="VYO11_000112"
     CDS             2944..4296
                     /locus_tag="VYO11_000112"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HEV1594743.1"
                     /translation="MGKYFGTDGVRGEANLELTPELAFKLGRFGGYVLSQHETEAPKV
                     FVGRDTRISGEMLESALVAGLLSVGIHVYKLGVLATPAVAYLVETEGASAGVMISASH
                     NPALDNGIKFFGGDGFKLDDEKEAEIEALLDAEEDTLPRPSAEGLGILVDYPEGLRKY
                     EGYLVSTGTPLDGMKVALDTANGAASTSARQIFADLGAQLTVIGETPDGLNINLNVGS
                     THPEALQEVVKESGSAIGLAFDGDSDRLIAVDENGDIVDGDKIMYIIGKYLSEKGQLA
                     QNTIVTTVMSNLGFHKALNREGINKAVTAVGDRYVVEEMRKSGYNLGGEQSGHVILMD
                     YNTTGDGQLSAVQLTKIMKETGKSLSELAAEVTIYPQKLVNIRVENVMKEKAMEVPAI
                     KAIIEKMEEEMAGNGRILVRPSGTEPLLRVMAEAPTTEEVDYYVDTITDVVRAEIGID
                     "
     gene            4370..4744
                     /locus_tag="VYO11_000113"
     CDS             4370..4744
                     /locus_tag="VYO11_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HEV1594744.1"
                     /translation="MNLKREQEFVSQYHFDARNFEWENENGAPETKVDVNFQLLQHDQ
                     ENQVTSLIVILSFMIVFDKFVISGTISQVNHIDGRIVNEPSELNQEEVETLARPCLNM
                     LNRLTYEVTEIALDLPGINLEF"
     gene            4746..5594
                     /locus_tag="VYO11_000114"
     CDS             4746..5594
                     /locus_tag="VYO11_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEV1594745.1"
                     /translation="MKLAVFTDSSAYLSEETLQREDLFVLDIPVNIDGEEYVEGINLS
                     AEEFYQKMAQASELPKTSQPSIAKLDEILTSLKEQGYTHALGLFLSSGISGFYQNIQY
                     MVDDYEGLTIAFPDTLITSAPLGIMVESVFNWRDQGDDFASIQDKLAIQISRTSAFIM
                     VDDLDHLVKGGRLSNGAAILGNLLSIKPILYFNDQGVIEVYEKVRTEKKATKRLIEII
                     KETTASGQYRVIVIHGNAPEKAEELRQHLLDFGLGSDVSLATFGSVIGTHLGAGSIAL
                     GYIPVI"
     gene            5871..6638
                     /locus_tag="VYO11_000115"
     CDS             5871..6638
                     /locus_tag="VYO11_000115"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HEV1594746.1"
                     /translation="MSIRVIIAGFKGKMGQAACQMVLTDPDLDLVAVLDPFESESEWQ
                     GIPVFKDKADLAGFEADVWVDFTTPAVAYENTRFALENGFAPVVGTTGFTSEEIAELK
                     EFSRAQDLGGLIAPNFALGAVLLMQFATQAAKYFPNVEIIELHHDKKKDAPSGTAIKT
                     AELMAEVRESIQQGAADEEELIAGARGADFDGMRIHSVRLPGLVAHQEVIFGNQGEGL
                     TLRHDSYDRISFMTGVNLGIKEVVKRHELVYGLEHLL"
     gene            6650..7834
                     /locus_tag="VYO11_000116"
     CDS             6650..7834
                     /locus_tag="VYO11_000116"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001138849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HEV1594747.1"
                     /translation="MPSEFQKALPVLEKIKEAGFEAYFVGGSVRDALLHSPIHDVDIA
                     TSSYPEETKQIFPRTADIGIEHGTVLVLDGDEEYEVTTFRTEDVYVDYRRPSAVSFVR
                     SLEEDLKRRDFTVNAFALDETGEIVDLFHGLEDLEKQVLRAVGVASERFNEDALRIMR
                     GFRFQASLGFALEPETFKAMKTLTPLLEKISVERTFVEFDKLLLAPFWRRGLASMIES
                     QAYDYLPDMASSQDKLNRLFDLETDFTFESSEQAWAALLWALEIENAQSFLKSWKTSR
                     QFAKQVQDLLIILALRENGELSKRDCYRFDIDLLLQAENLRQAQGKEVNPQAITEKYQ
                     SLTIHDKKEIQINGGILIKEYGYQPGPDLGEILTEIEFAIVDGELENNREAIHAYLRE
                     KK"
     gene            7831..9702
                     /locus_tag="VYO11_000117"
     CDS             7831..9702
                     /locus_tag="VYO11_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001279112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEV1594748.1"
                     /translation="MSDFIVEKLSKSVGDKTVFRDISFIIHDLDRIGLIGVNGTGKTT
                     LLDVLSGVSGFDGDVSPFSAKNDYQIGYLTQDPDFDDRKTVLDTVLSSELKEIQLIRE
                     YELIMLDYSEDKQARLERVMAEMDSLQAWEIESQVKTVLSKLGIQDLSTPVGELSGGL
                     RRRVQLAQVLLGNHDLLLLDEPTNHLDIAIIEWLTLFLKNSKKTVLFITHDRYFLDAL
                     STRIFELDRAGLTEYQGNYQDYVRLKAEQDERDAALLHKKEQLYKQELAWMRRQPQAR
                     ATKQQARINRFHDLKKEVSGSSAETDLTMNFETSRIGKKVIEFQAVSFAYENKPILQD
                     FNLLVQAKDRIGIVGDNGVGKSTLLNLIAGSLEPTKGQVVIGETVRIAYFSQQIEGLD
                     ESKRVINYLQEVAEEVKTSGGSTTSIAELLEQFLFPRSTHGTLIGKLSGGEKKRLYLL
                     KLLLEKPNVLLLDEPTNDLDIATLTVLENFLQGFAGPVLTVSHDRYFLDKVATKILAF
                     EDGKIRPFFGHYTDYLDEKAFETDMVNQVQKVEKEKVVKVREDKKRMTYQEKQEWASI
                     EGDIETLEKRIAAIEEEMQANGSDFGKLATLQKELDEKNEALLEKYERYEYLSEFDS"
     gene            complement(9845..11029)
                     /gene="mntE"
                     /locus_tag="VYO11_000118"
     CDS             complement(9845..11029)
                     /gene="mntE"
                     /locus_tag="VYO11_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDF family manganese efflux transporter MntE"
                     /protein_id="HEV1594749.1"
                     /translation="MKQSISNLKLAERGAIISISTYLILSAAKLATGHLLHSSSLVAD
                     GFNNVSDIIGNVALLIGIRMARQPADRDHRFGHWKIEDLASLITSIIMFYVGFDVLRD
                     TIQKILSREETVIDPLGATLGIISAAIMFVVYLYNTRLSKKSNSKALKAAAKDNLSDA
                     VTSLGTAIAILASSFNYPIVDKLVAIIITFFILKTAYDIFIESSFSLSDGFDDRLLED
                     YQKAIMEIPKISKVKSQRGRTYGSNIYLDITLEMNPDLSVFESHEIADQVESMLENRF
                     GVFDTDVHIEPAPIPEDEILDNVYKKLLMREQLIDQGNQLEELLTDDFVYIRQDGEQM
                     DKEAYKTKKELNSAIKDIQITSISQKTKLICYELDGIIHTSIWRRHETWQNIFHQETK
                     KE"
     gene            11333..14029
                     /locus_tag="VYO11_000119"
     CDS             11333..14029
                     /locus_tag="VYO11_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HEV1594750.1"
                     /translation="MSKEQKRQAFYTQSPEEVLQAVDATEQGLSSSEAEKRLAEFGHN
                     ELEEGEKRSILVKFIEQFKDLMIIILVAAAILSVVTSGGEDIADAIIILAVVIINAAF
                     GVYQEGKAEEAIEALKSMSSPVARVLRDGHMAEIDSKELVPGDIVALEAGDVVPADLR
                     LIEANSLKIEEAALTGESVPVEKDLSVELATDAGIGDRVNMAFQNSNVTYGRGMGVVV
                     NTGMYTEVGHIAGMLQDADETDTPLKQNLNNLSKVLTYAILVIALVTFVVGVFIQGKN
                     PLGELLTSVALAVAAIPEGLPAIVTIVLSLGTQVLAKRHSIVRKLPAVETLGSTEIIA
                     SDKTGTLTMNKMTVEKVFYDAVLHDSADDIELGLEMPLLRSVVLANDTKIDVEGNLIG
                     DPTETAFIQYALDKGYDVKGFLEKYPRVAELPFDSDRKLMSTVHPLPDGRFLVAVKGA
                     PDQLLKRCLLRDKAGDIAPIDEKVTNLIHTNNSEMAHQALRVLAGAYKIIDSIPENLT
                     SEELENDLIFTGLIGMIDPERPEAAEAVRVAKEAGIRPIMITGDHQDTAEAIAKRLGI
                     IDANDTEGHVLTGAELNELSDEEFEKVVGQYSVYARVSPEHKVRIVKAWQKQGKVVAM
                     TGDGVNDAPALKTADIGIGMGITGTEVSKGASDMILADDNFATIIVAVEEGRKVFSNI
                     QKTIQYLLSANTAEVLTIFLSTLFGWDVLQPVHLLWINLVTDTFPAIALGVEPAEPGV
                     MNHKPRGRKASFFSGGVLSSIIYQGVLQAALVMSVYGLAIAYPVHVGDNHAIHADALT
                     MAFATLGLIQLFHAYNVKSVYQSILTVGPFKSKTFNWSILVSFILLMATIVVEPLEGI
                     FHVTKLDLSQWGIVMAGSFSMIIIVEIVKFIQRKLGFDKNAI"
     gene            14042..14833
                     /gene="yghU"
                     /locus_tag="VYO11_000120"
     CDS             14042..14833
                     /gene="yghU"
                     /locus_tag="VYO11_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-dependent disulfide-bond
                     oxidoreductase"
                     /protein_id="HEV1594751.1"
                     /translation="MSAYQLPTVWQDEASNQGAFTGLNRPTAGARFEQNLPKGEQAFQ
                     LYSLGTPNGVKVTILLEELLEAGFKEAAYDLYKIAIMDGDQFGSDFVKLNPNSKIPAL
                     LDQSGTENVRVFESAHILLYLAEKFGAFLPSNPVEKVEVLNWLFWQAGAAPFLGGGFG
                     HFFNYAPEKLEYPINRFTMEVKRQLDLLDKELAQKPYIAGNDYTIADIAIWSWYGQLV
                     QGNLYQGSAKFLDASSYQNLVKWAEKIANRPAVKRGLEVTYTEIK"
     gene            14949..15359
                     /locus_tag="VYO11_000121"
     CDS             14949..15359
                     /locus_tag="VYO11_000121"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEV1594752.1"
                     /translation="MEKKIVKDILFLSQVSQPASQEDLYLARDLQDTLLANRDTCVGL
                     AANMIGVQKRVIIFNLGLVPVVMFNPVLLSFEGSYEAEEGCLSFVGVRSTKRYETTRL
                     AYRDSKWQEQTITLTGFPAQICQHELDHLEGRII"
     gene            15371..16966
                     /locus_tag="VYO11_000122"
     CDS             15371..16966
                     /locus_tag="VYO11_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000822862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1594753.1"
                     /translation="MKRIVFELIFIATTWYIFLPPLNLTSWEFLFFLCGHLLVVAILF
                     GFGKGINLVKTVHVRHGKAEAALNLEGFKINRLGKILLASIGGILLLAALVSLVTSSM
                     FQAKNYANVVTVTEKDFTEFPRSDTSKVPILDRSTAEKIGDRYLGSLTDKVSQYVAAD
                     TYTQLTIDGKPYRVTPLEYADPIKWFNNQAKGIGEYIKVDMVTGNADLVDLKTPIKYS
                     DSEYFNRDVKRHLRLKYPTKIFKTPSFEVDDEGNPFYVATVYQKQFGLAVPRPASVII
                     LDATNGETKEYSLSDVPEWVDRIYPAEETIEQINYNGKYKDGFLNAMISKKNVTQTTN
                     GYNYLSIGNDIYLYTGVTSANADESNLGFILENMRTGEITKYSLASATEESARESAEG
                     AVQEKSYKATFPILINLNDKPLYIMGLKDNAGLVKEYALVDAVEYQNVIVATTVEEML
                     SKYANKNDLEIDNATTESIKGVVADLKSAVIKGDTVYFFKVDGKIYKVKASVSDDLPY
                     LENGKTFEGQVGKDNYLKTFKVQ"
     gene            17155..17310
                     /locus_tag="VYO11_000123"
     CDS             17155..17310
                     /locus_tag="VYO11_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000508323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3953 domain-containing protein"
                     /protein_id="HEV1594754.1"
                     /translation="MGFYLMVASMLLGLLALKIGFSQFKEKKDKFLSILTSLAGTALV
                     LVAVWLG"
     gene            17398..18126
                     /gene="yaaA"
                     /locus_tag="VYO11_000124"
     CDS             17398..18126
                     /gene="yaaA"
                     /locus_tag="VYO11_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HEV1594755.1"
                     /translation="MKILIPTAKEMNTDLPSIEAIPLKPESQAVLDALALYSASQLES
                     FYKVSAEKAAEEFQNIQALKRQTAQHYPALKLFDGLMYRNIKRDKLTEAEQDYLENHV
                     FITSALYGVVPALSPMAPHRLDFLMKLKVAGKTLKSHWKAVYDEALKKEEVIFSLLSS
                     EFETVFSKEIRAKMVTFKFMEDRGGQLKIHSTISKKARGAFLTALIENQVQTVGEARR
                     LNFAGFVYREDLSQPQGLVFVKEV"
     gene            complement(18177..19661)
                     /locus_tag="VYO11_000125"
     CDS             complement(18177..19661)
                     /locus_tag="VYO11_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003096885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV1594756.1"
                     /translation="MRNLLSTKVQRQLRLMETLIQNRNWMKLHELAEKLGCTERILKS
                     DLNELRIAFPSINIQSSVNGIMIDLEVNTSVEDIYQYFLANSQSFQLLEYMFFNEGLP
                     IYRTIENLYFSSANLYRLGRNITKVLSSQFQIELSFTPSEIRGNEIDIRYFFAQYFSE
                     RYYFLDWPFPDLPEEDLTEFADFFYKITNYPMRFSIYRMYKLMIAISIHRVKNGHFID
                     LPNHFYKEYYPLLKSIPNFQETLAYFSKHFGLEMTPDTIAQIFISFLQNDIFLDPQEF
                     FNSLEDNSQARYSYQLLSQILERLSKQYKITFTNHDELIWHLHNTAFFERQEIFSTPI
                     LFEQKALTIKKFEVYFPDFMGSARQELAQYRQAIGQHDHPEQLEHLMYTILTHAENLS
                     TQLLENRPPIKVLIISNFDHAISLTFVDMLSYYCNNRFTFDIWDELKTSPEILNQTDY
                     DIIVSNFYIPGITKKFICRNHLSIMNLVNHLNTLSNEIHLSNTL"
     gene            19877..25366
                     /locus_tag="VYO11_000126"
     CDS             19877..25366
                     /locus_tag="VYO11_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HEV1594757.1"
                     /translation="MKHSHKKSFDWYSMQQRYSIRKYYFGAASVLFGTALVLGAAASV
                     QTVQAEENKQETTNSISVGRGEAATKPAEVSASNKEKTYAAPTVANPVETTPVKTEEV
                     TKPAEKVEEAKDKKEEVTHQDAVDKSKLLTALSRAKKLESKLYTEASAANLQTSIQAG
                     QSLLGKADASEAELSAAESSIQSSIIGLELRSNSNKGTVSETPVAKKANIVEAKEETN
                     PAATTDRSAVDSAILPTSTADKVETTSAPASINEILKLGLSLSDARQNPAIRKEDVNR
                     GYSGFRAAPAPTNKLVTNLGNNTVFTDISRGSHTFRGNGNSRGGNPIHFDVTTTRVGN
                     RVEFSIAYSGPGEFVNNNFLLDKGNGFGEPSRATISTNRLRDQTKDIRKGANFVSHSS
                     YSLTSAVETNSNQTIRFSLPIANPNGDLSVRLRPVTFNVGQGESGSATSNDPYSNSNY
                     YFREKPLLLDANPNGGTNNKTVSEDIDFQTVYLPTSKLPEGQTRLVREGEKGQRQIIY
                     KVHQLGNETILGLPISNSVIKEVKPRIMQIGVAKDLIDTVKPRVDQNKVGDTNNLTFY
                     LDNDGNGVYTEGVDELVQKIAIKDGAKGEKGVQGERGLTGAQGQAGRDGVTPTVTVKD
                     NKNDGTHTITINDGRGNVASTVVRDGFDGASPLVATQRNEADKTTTVIFYYDQNGNNE
                     LDASDKKLKEVIIADGAKGEQGLQGRDGAQGPKGADGQRGPAGPQGPKGEQGNPGTPG
                     KDGKSLIAVKNGTETKVYVEDPARPGQPLNPNQPLATITDGRNGTNGQSPTITATRSV
                     QNGKNGVLVTITPVGGRPQTTFVEDGQKGADGKTPTVTITEGQNGTHTLTVHNPGSPD
                     VTTTIRDGATGQAGRDGKDVLNGKVNPQPNQGKNGDKYINTETGDVYVKNNGNWDKEG
                     NIKGPKGDKGADGAKGEKGDQGERGLTGAQGAKGADGAVGRDGRDGKDVLNGKANPEA
                     HQGKDGDKYVNTETGDVFVKNNGNWDKEGNIKGPKGDKGERGEDGKTPEVTVTPGKDG
                     HSTDITFTVPGKDPVTVNVKDGENGLNGKTPKVDLLRVQGKNGNPSHTIVTFYTDENN
                     DGKYTPGTDELLGSEMIKDGAKGADGRDGKSLLTVKDGKETKVYQEDPANPGQPLNPE
                     KPLAVIRDGVDGKSPTVTAVRKDEAGHKGVEITVDNHDGSQPTTVFVQDGAKGETGAT
                     GQDGQTPTITTQRGQDGQSTVVTITTSGKDPVTFTVKDGKNGKDGRAPKIKVEDITSP
                     SRIRRDTDAAATPTRNGIRVTVYDDVNDNGVYDGGVDKVLNSKDIYNGIDGRDGSAPT
                     ITTKDNGDGTHTITVQNPDGSESTTVVKDGKDGKTANITTTENPDGSHTITVTNPDGS
                     TKETVVKNGKDGKTPKVEVTDNNDGTHTVKVTDGDGNVTNAIIKDGKDGKAATATTTE
                     NPDGSHTVTITNPDGTKNEFVVKNGRDGVDGRTPTASVRDNGDGSHTIVITNPEGVTT
                     ETTVRDGKSPKVTITDEQNGTHKISVLNGDGTTTETIITDGKSPVATVRDNQDGTYTI
                     RVENGNGTVSETTVRDGKSPKANIVDNGDGTHTLTIVDSDGREYKSIIKDGKDGKDSV
                     SPTVTVKNNNDGTHVVTITNPDGSKTEMVIKDGKDGKSPKVSVEDNGDGSHTITIINS
                     DGTVTKTVIKDGRDGRDGRDGKDGKDGKDGKCGCQDKPVTPSNDKPVPPTPNVPTPEV
                     PVKPVPAQPTPNVPTPEVPVQPTPAVPTPEVPVKPVPAVPEQPVVPTPAQPATPVNAN
                     PVAPTTGKENRGDKLPETGSQSDYISVLLGSGILLSLYVGRRKEA"
     gene            complement(25603..26151)
                     /locus_tag="VYO11_000127"
     CDS             complement(25603..26151)
                     /locus_tag="VYO11_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEV1594758.1"
                     /translation="MSKKVLFIVGSLRQGSFNHQMALEAEKALAGKAEVSYLDYSALP
                     LFSQDLEVPTHPAVAAAREAVLVADAIWIFSPVYNFSIPGTVKNLLDWLSRALDLSDT
                     RGVSALQDKFVTVSSVANAGHDQLFAIYKDLLPFIRTQGVGDFTAARVNDSAWADGKL
                     VLEETVLNSLEKQAQDLVEAIQ"
     gene            26472..26960
                     /locus_tag="VYO11_000128"
     CDS             26472..26960
                     /locus_tag="VYO11_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HEV1594759.1"
                     /translation="MKKRQNKAKNNLLWQYGLGMTILFVVISASFLYMVSLSMKPYQT
                     AKSEGEKLAQQYAGLEQADQVDLYNGLESYYSVLGRNKQQEALAVLIGKDDHKIYVYQ
                     LNQGVSQEKAETVSKEKGAGEIDKIIFGRYQDKPIWEVKSGSDFYLVDFETGALVNKE
                     GL"
     gene            26957..28144
                     /locus_tag="VYO11_000129"
     CDS             26957..28144
                     /locus_tag="VYO11_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEV1594760.1"
                     /translation="MKLSNRVLEMEESVTLAAGARAKALKAEGRDILSLTLGEPDFTT
                     PKNIQDAAIASIRDGRASFYTVTSGLPELKAAVNSYFERFYGYSVASNQVTVAAGAKY
                     SLYTFFMAVVNPGDEVIIPTPYWVSYGDQVKMAEGVPVFVSAKEDNHFKVTVEQLEAA
                     RTDKTKVLVLNSPSNPTGMIYTREELLAIGNWAVENDILILADDIYGRLVYNGHEFTP
                     ISSLSEAIRKQTVVINGVSKTYAMTGWRIGYAVGEADIIAAMSKIAGQTTSNPSAVAQ
                     YAAVEALSGEQDTVESMRQAFEERLNTIYPLLAEVPGFEVVKPQGAFYLFPNVKKAME
                     MKGYTDVTDFTTVILEEAEVALVTGAGFGAPENVRLSYATDLDTLKEAVERLKAFMGS
                     END"
     gene            28137..28502
                     /locus_tag="VYO11_000130"
     CDS             28137..28502
                     /locus_tag="VYO11_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEV1594761.1"
                     /translation="MIDHFEIKVKDLQISEGFYRSFLAPLDYKLAFKTSSLISFLSPN
                     SPHPGGDFWLTQGTQDPVHFAFLAENKEEVQACYEAGLEAGGRDNGAPGYRSEHPIYY
                     AAFMIDLDGNNIEVVCHKE"
     gene            28518..29864
                     /gene="asnS"
                     /locus_tag="VYO11_000131"
     CDS             28518..29864
                     /gene="asnS"
                     /locus_tag="VYO11_000131"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HEV1594762.1"
                     /translation="MMTKRVTIIDVKDYVGQEVTIGAWVANKSGKGKIAFLQLRDGTA
                     FFQGVAFKPNFVEKFGEEVGLEKFDVIKRLSQETSVYVTGIVKEDERSKFGYELDITD
                     IEVIGESQDYPITPKEHGTDFLMDNRHLWLRSRKQVAVLQIRNAIIYATYEFFDKNGF
                     MKFDSPILSGNAAEDSTELFETDYFGTPAYLSQSGQLYLEAGAMALGRVFDFGPVFRA
                     EKSKTRRHLTEFWMMDAEYSYLTHDESLDLQEAYVKALLQGVLDRAPQALETLERDTE
                     LLKRYIAEPFKRITYDQAIDLLQEHENDEDADYEHLEHGDDFGSPHETWISNHFGVPT
                     FVMNYPAAIKAFYMKPVPGNPERVLCADLLAPEGYGEIIGGSMREEDYDALVAKMDEL
                     GMDRTEYEFYLDLRKYGTVPHGGFGIGIERMVTFAAGTKHIREAIPFPRMLHRIKP"
     gene            30017..30307
                     /locus_tag="VYO11_000132"
     CDS             30017..30307
                     /locus_tag="VYO11_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018030687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HEV1594763.1"
                     /translation="MAKYEILYIIRPNIEEEAKNALVARFDSILTDNGATVVESKTWE
                     KRRLAYEIQDFREGLYHIVNVEANDDAALKEFDRLSKINADILRHMIVKIDA"
     gene            30319..30789
                     /gene="ssbA"
                     /locus_tag="VYO11_000133"
     CDS             30319..30789
                     /gene="ssbA"
                     /locus_tag="VYO11_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein SsbA"
                     /protein_id="HEV1594764.1"
                     /translation="MINNVVLVGRMTRDAELRYTPSNVAVATFTLAVNRTFKSQNGER
                     EADFINVVMWRQQAENLANWAKKGSLIGVTGRIQTRSYDNQQGQRVYVTEVVAENFQM
                     LESRSVREGHTGGAYSAPTANYSAPTNSVPDFSRNENPFGATNPLDISDDDLPF"
     gene            30821..31060
                     /locus_tag="VYO11_000134"
     CDS             30821..31060
                     /locus_tag="VYO11_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HEV1594765.1"
                     /translation="MAQQRRGGFKRRKKVDYIAANKIEYVDYKDTELLSRFVSERGKI
                     LPRRVTGTSAKNQRKVTTAIKRARVMALMPFVNED"
     gene            31355..32755
                     /locus_tag="VYO11_000135"
     CDS             31355..32755
                     /locus_tag="VYO11_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional Cof-type HAD-IIB family
                     hydrolase/peptidylprolyl isomerase"
                     /protein_id="HEV1594766.1"
                     /translation="MDAKLRYKAKKIKIVFFDIDDTLRNSKTGFIPTTIPTVFKQLRE
                     KGILIGIASGRGIFGVVPEIRDLKPDFFVTLNGAYIEDKKGQVIYQHQIEKSDVEEYI
                     SWAKQEGIEYGLVGSHDAKLSTRTDMMSEAINPIYPDLDVDPDFHEKEDIYQMWTFED
                     KGDDLHLPDSLSDKLRMVRWHQHSSDIVPISGSKATGVEKVVEHLGLKPEKVMVFGDG
                     LNDLELFDYAGISVAMGISHDKIKEKADYITKTLEEDGIFAALEVFGMVEKELHFPQV
                     DIETVEGPLATIKTNHGDLRIKLFPEHAPKTVANFVSLSKDGYYDGVIFHRIIKDFMI
                     QGGDPTGTGMGGQSIYGESFEDEFSEELYNIRGALSMANAGPNTNGSQFFIVQNQHLP
                     YSKKEITRGGWPEPIAEIYANQGGTPHLDRRHTIFGQLADEASYAVLDAIAAVETGAM
                     DKPVEDVVIETIEIED"
     gene            32757..33116
                     /locus_tag="VYO11_000136"
     CDS             32757..33116
                     /locus_tag="VYO11_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HEV1594767.1"
                     /translation="MKIGDKLKGRITGIQPYGAFVELETGDTGLIHISEIRTGFIENI
                     HETLKVDEEVQVQVVDLDEFTGKASLSIRTLEEEKYQFPRRRRFSSDRFNYGFAPFRR
                     MLPIWTGEALHHLKKKK"
     gene            33170..33919
                     /locus_tag="VYO11_000137"
     CDS             33170..33919
                     /locus_tag="VYO11_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HEV1594768.1"
                     /translation="MEEEQLLKSGERINQLFSTDIKIIQNREVFSYSVDSVLLSRFPR
                     FPKKGLIVDFCAGNGAVGLFASTRTQAQILSVEIQERLADMAERSVRLNGLEEQMQVI
                     CDDLKNMPAHIQGSKVDMILCNPPYFKVDPHSNLNESEHYLLARHEITTNLEEICHSA
                     QSILKSNGRLAMVHRPDRLLDILDTLKRHNLAPKRLQFVYPKREKEANMLLIEAIKDG
                     STSGFKVLPPLIVHNDDGSYTPEIEEIYYGS"
     gene            33909..34208
                     /locus_tag="VYO11_000138"
     CDS             33909..34208
                     /locus_tag="VYO11_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HEV1594769.1"
                     /translation="MDHKAYMYVLECRDGSYYIGYTTDMRRRLAIHNSGKGAKYTRAR
                     LPVKLIYAQGFASKEEAMSAEALLKRKKRPQKEEFLSENQDRNLLSYFEESWGVL"
     gene            34279..35214
                     /locus_tag="VYO11_000139"
     CDS             34279..35214
                     /locus_tag="VYO11_000139"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HEV1594770.1"
                     /translation="MSKILVFGHQNPDSDAIGSSVAFAYLAKEAYGLDTEAVALGTPN
                     EETAFVLNYFGVEAPRVITSAKAEGAEQVILTDHNEFQQSVSDIAEVEVYGVVDHHRV
                     ANFETASPLYMRLEPVGSASSIVYRMFKEHGVAVPKEIAGLMLSGLISDTLLLKSPTT
                     HPTDKIIAPELAELAGVNLEEYGLAMLKAGTNLASKSAEELIDIDAKTFELNGNNVRV
                     AQVNTVDIAEVLERQAEIEAAMQAANESNGYSDFVLMITDIVNSNSEILALGANMDKV
                     EAAFNFKLENNHAFLAGAVSRKKQVVPQLTESFNA"
     gene            35301..35813
                     /locus_tag="VYO11_000140"
     CDS             35301..35813
                     /locus_tag="VYO11_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000892254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoylalanyl-D-glutamate--2,
                     6-diaminopimelate ligase"
                     /protein_id="HEV1594771.1"
                     /translation="MLENGDLIFVRDGSDMGQAIQTSTGNYSHVAIYLDGMIYHASGQ
                     AGVVCQEPADFFESNHLYDLYVYPEMDIQSVKERACRHLGAPYNASFYPDAAAFYCSQ
                     YIAEILPIFETIPMKFGDGEQEISDFWREYYIELGLPVPLNQAGTNPSQLAASPLLQC
                     KERDLHDSDF"
     gene            35850..36446
                     /locus_tag="VYO11_000141"
                     /pseudo
     CDS             35850..36446
                     /locus_tag="VYO11_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809149.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
     gene            36547..36741
                     /locus_tag="VYO11_000142"
     CDS             36547..36741
                     /locus_tag="VYO11_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HEV1594772.1"
                     /translation="MSLENKLEQATGAVKEGFGKVTGDSKTELEGAVEKTVSKAKDVV
                     EDAKGAVEGAVEGLKNVFTK"
     gene            complement(36787..38232)
                     /locus_tag="VYO11_000143"
     CDS             complement(36787..38232)
                     /locus_tag="VYO11_000143"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HEV1594773.1"
                     /translation="MIKIETVLDILKKDGLFREIIDQGHYHYNYSKVVFDSISYDSRK
                     VTEDTLFFAKGAAFKKEYLLSAITQGLAWYIAEKDYEVGIPVIIVNDIKKAMSLIAME
                     FYGNPQEKLKLLAFTGTKGKTTAAYFAYNILSQGHRPAMLSTMNTTLDGETFFKSALT
                     TPESIDLFDMMNQAVQNDRTHLIMEVSSQAYLVKRVYGLTFDVGVFLNISLDHIGPIE
                     HPSFEDYFYHKRLLMENSRAVIINSDMDHFSVLKEQVEDQDHDFYGSQFDNQIENSKA
                     FRFSATGKLAGDYDIQLIGNFNQENAVAAGLACLRLGASLEDIKKGIAATRVPGRMEV
                     LTQKNGAKVFIDYAHNGDSLKKLINVVETHQTRKIALVLGSTGNKGESRRKDFGLLLN
                     QHPEIQVFLTADDPNYEDPMAIADEISSYINHPVEKIADRQEAIKAAMAITNHELDAV
                     IIAGKGADCYQIIQGKKESYPGDTAVAENYL"
     gene            38338..39960
                     /locus_tag="VYO11_000144"
     CDS             38338..39960
                     /locus_tag="VYO11_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HEV1594774.1"
                     /translation="MSHENNHQQAQMLRGTAWLTASNFISRLLGAVYIIPWYIWMGAY
                     AAKANGLFTMGYNIYAWFLLVSTAGIPVAVAKQVAKYNTMREEEHSFALIRSFLGFMT
                     GLGLVFALVLYVFAPWLADLSGVGKDLIPIMQSLAWGVLIFPSMSVIRGFFQGMNNLK
                     PYAMSQIAEQVIRVIWMLLATFIIMKLGSGDYLAAVTQSTFAAFVGMVASFAVLIYFL
                     AQEGSLKRVFETGDKINSKRLLVDTIKEAIPFILTGSAIQLFQILDQLTFINSMSWFT
                     NYSNEDLVVMFSYFSANPNKITMILISVGVSIGSVGLPLLTENYVKGDLKAASRLVQD
                     SLTLLFMFLLPATVGVVMVGEPLYTVFYGKPDSLALGLFVFAVLQSIILGLYMVLSPM
                     LQAMFRNRKAVLYFIYGSIAKLVLQLPTIALFHSYGPLISTTIALIIPNVLMYRDICK
                     VTGVKRKVILKRTILISLLTLVMFLLIGTIQWLLGFFFQPSGRLWSFFYVALVGAMGG
                     GLYMVMSLRTYLLDKVIGKAQADRLRAKFKLS"
     gene            40163..42124
                     /locus_tag="VYO11_000145"
     CDS             40163..42124
                     /locus_tag="VYO11_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV1594775.1"
                     /translation="MKKSKSKYLTLAGLVLGTGVLLSACGNSSTASKTYNYVYSSDPS
                     SLNYLAENRATTNDIVTNLVDGLMENDQYGNYVPSLAEDWTVSQDGLTYTYKLRKDAK
                     WFTSEGEEYAPVTAQDFVTGLQYAADKKSEALYLVQDSVAGLDDYITGKTSDFSTVGI
                     KALDDQTVQYTLARPEPYWNSKTTSTILFPVNADFLKSKGDDFGKVDPANILYSGPFL
                     MKAFVSKSVIEYKKNPNYWDAKNVFVDDVKLTYYDGSDQDALVRNFTDGAYSYARLYP
                     NSSSFEGIKEKYKDDIIYSMQDATSYYWNFNLDRQAYKFTSKTTDIEKKSTQEAVLNK
                     NFRQAINFAYDRTSYGAQTQGEDGATKILRNLVVPPTFVSIKGKDFGEVVASKMVNNY
                     GKEWQGINFADGQDPYYNPEKAKAKFAEAKKELEAKGVQFPIHLDATVDQASKKGIQE
                     VSSMKQSIEAALGTENVVIDIQQLSTEDYDNSSYLAQTAIQKDYDLYNGGWSPDYLDP
                     STYLDIFSVKNGGVLQNLGLDPGEANDKAKAVGLDTYTQMLEEANKEQDPAKRYEKYA
                     DIQAWLIDSSLAIPNVSLGGTPSLRKTVPFSAPYSLAGNKGVESYKYLKVQDKIVTTD
                     EYAKAREKWLKEKEESNKKAQEELAKHVK"
     gene            42296..43183
                     /locus_tag="VYO11_000146"
     CDS             42296..43183
                     /locus_tag="VYO11_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1594776.1"
                     /translation="MKLKLLRVDTKVIMGSFLLVLSSLLALLLPLILKGLIDGSSIEN
                     IGSKVFQSFLIFIGQALFSSIGYYLFSQSGEKKIAKIRKKVIEGLIYAEKSFFDKSQS
                     GELTSAIVNDMSVIREFLITTFPNIILSLVMVLGSIVVLFSLDWNLSLLLFITLPCMM
                     FIILPLSNISEKYSRRLQKEIGFLTGQLTEKIQEHELIKTNQAEKSVQNVLDNCIERV
                     QNNSLKSDRVTSFETPFALLFIFATIAVMLTYGSYRVSAGYISVGTLVSFLIYLFQLL
                     NPISNIANFVTVYSRSKGS"
     gene            43256..43978
                     /locus_tag="VYO11_000147"
     CDS             43256..43978
                     /locus_tag="VYO11_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV1594777.1"
                     /translation="MNFNHVYFGYDENRPVLKDITCSIFKGQKIAFVGPSGSGKSTIV
                     RLLERFYKPLSGDILMEQSSIYDFNLKEWRSKIAWVSQNNAVLSGSIRDNLCLGLNRL
                     VTDDELMKVLDLVSLGDEIRSMKEGLDTEVGERGRFLSGGQSQRLQIARTYLKDAEIL
                     IFDEATANLDADSEYAIISSLYSVLKEKTVVIIAHRLSTVKDVDCIFFLEEGKITGSG
                     THKELLENHERYARFVQEQMIE"
     gene            44135..45229
                     /locus_tag="VYO11_000148"
     CDS             44135..45229
                     /locus_tag="VYO11_000148"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HEV1594778.1"
                     /translation="MSKELHINTILAQAGIKSDEATGALVTPLHFSTTYQHPEFGRST
                     GFDYTRTKNPTRSKAEEVLAAIESADYALATSSGMSAIVLAFSVFPVGSKVLAVRDLY
                     GGSFRWFNQVEQEGHFHFTYANTEEELIAELEKDVDVLYIETPTNPLMLEFDIEKLAK
                     LAHAKGAKVVVDNTFYSPIYQRPIEDGADIVLHSATKYLAGHNDVLAGVVVTNSLELY
                     EKLFYNLNTTGAVLSPFDSYQLLRGLKTLSLRMERSTANAQEVVAFLKDSPAVKEVLY
                     TGRGGMISFKVADETRIPHILNSLKVFSFAESLGGVESLITYPTTQTHADIPAEVRHS
                     YGLTDDLLRLSIGIEDARDLIADLRQAIEG"
     gene            45237..46403
                     /locus_tag="VYO11_000149"
     CDS             45237..46403
                     /locus_tag="VYO11_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEV1594779.1"
                     /translation="MGKYDFTSLPNRLGHHTYKWKETETDSEVLPAWIADMDFVVLPE
                     IRQAVQTYADQLVYGYTYASEDLIKEIQKWEATQYGYNFDKEALVFIEGVVPAISTAI
                     QTFTKEGEAVLINTPVYPPFARSVKLNNRRLITNSLVEKDGLFEIDFDQLEKDLVEEE
                     VKLYILCNPHNPGGRVWEKEVLEKIGQLCQKHGVLLVSDEIHQDLTLFGHKHQSFNTI
                     NPAFKNFAIVLSSATKTFNIAGTKNSYAVIENPKLRLAFQKRLLANNQHEISGLGYLA
                     TEAAYRYGKDWLEELKQVFEDHINYVVDLFGKETKIKVMKPQGTYLIWLDFSAYDLTD
                     ETLQELLRNEAKVILNRGLDFGEEGSLHARINIAMPKSLLQEVCQRIVATFAKC"
     gene            46496..49594
                     /locus_tag="VYO11_000150"
     CDS             46496..49594
                     /locus_tag="VYO11_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEV1594780.1"
                     /translation="MAKLIPGKIRIEGVALYETGKVDIIKEKNNRLYARVAEEELRYS
                     LEDDLVFCACDFFQKRGYCVHLAALEHFLKNDERGQEILWSLEEGHEEKEAVETKVTL
                     GGKFLDRILSPKSECAYELSAVGQVEAGTNHILWTLRIGQINSQKYYIIRDIPLFLRI
                     VEQRKSYMIGKIYEESLSWEAFDDASQELLTFLHGLTEEGLVPDLFFQNQGRHLFFPL
                     TFFEQGVNLLMALPHFQFDHQVDSYQTLLFQDMHADANLFAFAVTEYSDYFEMEISES
                     PRVNVFYQGAVLFHKGQVYFLTDQQMRLLKEIKALPVGQQGKKYLQFDSSDRDKLASC
                     LTLFIQMGTVSAPERLQIKTFAPSFYFDREEDNRIRLEIQFDYGNRQVSSRQELEELP
                     FSSDADLEERIFQVCLAAGFEADFQSWRQALKAESVYHFFHDIIPVFEKLGHVDLSDK
                     LEELYSLASPQVQIASKGGLLEIQFDFQNIAQEEIDQAMQALVANQDFYIDSSNQVYF
                     FDEETRKIRQNLQELGQFELKDGTLQARKSLAYSLAHLFEGRDRVSFSQEFQNLAQDL
                     THPEDFPLQATQVKADLRDYQEKGIGWLQMLHHYGFGGILADDMGLGKTLQTIAFLTS
                     QVTKESRVLILAPSGLIYNWADEFQKFAPQLDVAVVHGLKASREEILAESHQIYVTSY
                     ATFRQDSEFYQGMAFDFLFLDEAQVMKNAQTKIAQTLRQFVVPSVFALSGTPIENHLG
                     ELWSIFQIVMPGLLPSKKEFMKLPAERVAQFIKPFVMRRKKEEVLTELPDLIEVVYKN
                     ELEDQQKAIYLAQLQQMRDHLAQVSEQEFQRSRVEILSGLMRLRQICDTPALFMEDYQ
                     GASGKLDSLRDLLVQVADGGHRVLIFSQFKGMLEKIEQELPDLGLTSFKITGSTPAKE
                     RQDMTKAFNQGERDAFLISLKAGGVGLNLTGADTVILVDLWWNPAVEAQAIGRAHRMG
                     QEETVEVYRLVTKGTIEEKIQELQEQKKHLVSQVLDGTESRGSLTLAEIREILGISEA
                     ST"
     gene            49642..50259
                     /locus_tag="VYO11_000151"
     CDS             49642..50259
                     /locus_tag="VYO11_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HEV1594781.1"
                     /translation="MKQERFPLVSDDEVMLTEMPVMNLYDESDLISNIKGEYRDKNYL
                     EWAPITEEKPVKPIEKQVEKPKKAPLGVKKEGKSYAEVAREEARADLKKKRSANYLTQ
                     DFSLARRHSQPSLVRQGNQPTTPFQKENPGEFVKYSQKLTQSHYILAEEVHSIPTKNE
                     EVSAPAPKKNNYDFLKKSQIYNKKSKQTEQERRVAQELNLTRMTE"
     gene            50270..51604
                     /locus_tag="VYO11_000152"
     CDS             50270..51604
                     /locus_tag="VYO11_000152"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HEV1594782.1"
                     /translation="MSKTYHFIGIKGSGMSALALMLHQMGHKVQGSDVEKYYFTQRGL
                     EQAGITILPFDEKNLDGDMEIIAGNAFRPDNNVEIAYADQNGISYKRYHEFLGSFMRD
                     FVSMGVAGAHGKTSTTGMLSHVLSHITDTSFLIGDGTGRGSANAKYFVFESDEYERHF
                     MPYHPEYSIITNIDFDHPDYFTSLEDVFNAFNDYAKQITKGLFVYGEDAELRKITSDA
                     PIYYYGFEAEGNDFVASDLLRSTTGSTFTVHFRGQNLGQFHIPTFGRHNIMNATAVIG
                     LLYTAGFDLNLVREHLKTFAGVKRRFTEKIVNDTVIIDDFAHHPTEIIATLDAARQKY
                     PSKEIVAVFQPHTFTRTIALLDDFAHALNQADAVYLAQIYGSAREVDHGDVKVEDLAN
                     KINKKHQVITVENVSPLLDHDNAVYVFMGAGDIQTYEYSFERLLSNLTSNVQ"
     gene            51614..52078
                     /locus_tag="VYO11_000153"
     CDS             51614..52078
                     /locus_tag="VYO11_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1594783.1"
                     /translation="MEIPIKIIQASKFDLPEIGALQTSSFPAEKQQLSHILEESIRKC
                     ADTFLLARDENQLLGYILSSPQSDNPQCLKVHSLVIESDHQRQGLGTLLLAALKEVAV
                     ELDYKGIRLESPDELLSYFEMNGFVDEEETLLYATSQGYSMIWFNPFYLEEQ"
     gene            52075..52569
                     /locus_tag="VYO11_000154"
     CDS             52075..52569
                     /locus_tag="VYO11_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000702438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1594784.1"
                     /translation="MKIRQARLEDLDRIVELEFENFSVEEAIPPSVFEAHLREIQTSF
                     LVAEKEGRIMGYIEGPVGLHRHLQDQSFTEEIKDYSHEPGGYISVTCLSIAKEAQGLG
                     LGQKLLTALKEVALEDERDGINLTCHDYLIAYYEKHGFVNEGQSQSTFAGETWYDMVW
                     EMKK"
     gene            52650..54305
                     /gene="mltG"
                     /locus_tag="VYO11_000155"
     CDS             52650..54305
                     /gene="mltG"
                     /locus_tag="VYO11_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HEV1594785.1"
                     /translation="MSEKSREEEKLSFKEQILRDLEKVKGYDEVLKEDEAVVRTPANE
                     PSAEELMADSLSTVEEIMRKAPTVPTHPSQGVPASPADESQRETPGVPSHPSQDVPSS
                     PAEESGSRPGPGPVRPKKLEREYNETPTRVAVSYTTAEKKAEQAGPETPTPATEIVDI
                     ISDTSRRSRREGAKPVKPKKEKKSHVKAFVISFLVFLALLSAGGYFGYQYVLDSLLPI
                     DANSKKYVTVGIPEGSNVQEIGTTLEKAGLVKHGLIFSFYAKYKNYTDLKAGYYNLQK
                     SMSTEDLLKELQKGGTDEPQEPVLATLTIPEGYTLDQIAQAVGQLQGDFKESLTAEAF
                     LAKVQDETFISQAVAKYPTLLESLPVKDSGARYRLEGYLFPATYSIKESTTIESLIDE
                     MLAAMDKNLSPYYSTIKSKNLTVNELLTIASLVEKEGAKTEDRKLIAGVFYNRLNRDM
                     PLQSNIAILYAQGKLGQNISLAEDVAIDTNIDSPYNVYKNVGLMPGPVDSPSLDAIES
                     SINQTKSDNLYFVADVTEGKVYYANNQEDHDRNVAEHVNSKLN"
     gene            54376..54858
                     /gene="greA"
                     /locus_tag="VYO11_000156"
     CDS             54376..54858
                     /gene="greA"
                     /locus_tag="VYO11_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018370745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HEV1594786.1"
                     /translation="MAEKTYPMTLEEKEKLEKELEELKLVRRPEVVERIKIARSYGDL
                     SENSEYEAAKDEQAFVEGQISSLETKIRYAEIVNSDAVAQDEVAIGKTVTIQEIGEDE
                     EEVYIIVGSAGADAFAGKVSNESPIGQALIGKKTGDTATIETPVGSYDVKILKVEKTA
                     "
     gene            complement(55071..55148)
                     /locus_tag="VYO11_000157"
                     /pseudo
     CDS             complement(55071..55148)
                     /locus_tag="VYO11_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            55276..55674
                     /locus_tag="VYO11_000158"
     CDS             55276..55674
                     /locus_tag="VYO11_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1594787.1"
                     /translation="MENKESHKSQEIGNLIRVYNRSKREEAESEPLNLYVEDEKGNLL
                     AGLIAETFGNWLEIEYLFVKEELRGQGIGSKLLQQAESEAKNRNCCFAFVNTYQFQAP
                     DFYQKHGYKEVFSLQDYLYIRQRYYYQKNL"
     gene            56132..57139
                     /locus_tag="VYO11_000159"
     CDS             56132..57139
                     /locus_tag="VYO11_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HEV1594788.1"
                     /translation="MQDNYTTKAKHLTIDSRRLIERWKKEGKSNREIASLLGKAPQTI
                     HTEIKRGTVRQCLGKGRFKEVYSADYAQQSYENNRKRSVKKSSVTKELKEKILHYHNQ
                     KFSPEMMVMAKGVNVGISTIYYWIHHGKLGLSKQDLLYPRKGKALKKQASTNFKPAGQ
                     SIEQRSEAINLRLENGHYEIDTVLLTRAKNYCLLVLTDRKSRHQIIRLIPNKSAEVVN
                     QALKLILKQHKILSITADNGTEFNRLFDVFSEEHIYYAHPYAFWERGTNENHNRFIRR
                     WLPKGTKKMTPKEVAFIEKWINNYPKKCLDYKSPREDFWMANLNLKFSKMEIIFIKRF
                     Q"
     gene            57214..57414
                     /locus_tag="VYO11_000160"
     CDS             57214..57414
                     /locus_tag="VYO11_000160"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit C"
                     /protein_id="HEV1594789.1"
                     /translation="MNLTFLGLCIACMGVSVGEGLLMNGLFKSVARQPDMLSEFRSLM
                     FLGVAFIEGTFFVTLVFSFIIK"
     gene            57449..58165
                     /gene="atpB"
                     /locus_tag="VYO11_000161"
     CDS             57449..58165
                     /gene="atpB"
                     /locus_tag="VYO11_000161"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HEV1594790.1"
                     /translation="MEESINPIISIGPVIFNLTMLAMTLLIVGVIFVFIYWASRNMTL
                     KPKGKQNVLEYVYDFVIGFTEPNIGSRYMKDYSLFFLCLFLFMVIANNLGLMTKLQTI
                     DGTNWWSSPTANLPYDLTLSFLVILLTHIESVRRRGFKKSIKSFMSPVFVIPMNILEE
                     FTNFLSLALRIFGNIFAGEVMTSLLLLLSHQAIYWYPVAFGANLAWTAFSVFISCIQA
                     YVFTLLTSVYLGNKINIEEE"
     gene            58179..58673
                     /gene="atpF"
                     /locus_tag="VYO11_000162"
     CDS             58179..58673
                     /gene="atpF"
                     /locus_tag="VYO11_000162"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HEV1594791.1"
                     /translation="MHVTVGELIGNFILITGSFILLLVLIKKFAWSNITGIFEERAEK
                     IASDIDRAEEARQKAEVLAQKREDELAGSRKEAKTIIENAKETAEQSKANILADAKLE
                     AGHLKEKANQEIAQNKAEALQSVKGEVADLTISLAGKIISQNLDGHAHKELIDQYIDQ
                     LGEA"
     gene            58673..59209
                     /locus_tag="VYO11_000163"
     CDS             58673..59209
                     /locus_tag="VYO11_000163"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HEV1594792.1"
                     /translation="MDKKTVKVIEKYSMPFVQLVLEKGEEDRIFSDLTQIKQVAEETG
                     LPSFLKQVAVDESDKEKTIAFFQDSVSPLIQNFIQVLAYNHRANLFYDVIVDCLNRLE
                     KETNRFEVTITSAHPLTDEQKTRLLPLIEKKMSLKVRSVKEQIDESLIGGFVIFANHK
                     TIDVSIKQQLKVVKENLK"
     gene            59224..60729
                     /locus_tag="VYO11_000164"
     CDS             59224..60729
                     /locus_tag="VYO11_000164"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HEV1594793.1"
                     /translation="MAINAQEISALIKQQIENFKPNFDVTETGVVTYIGDGIARAHGL
                     ENVMSGELLNFENGSYGMAQNLESTDVGIIILGDFTDIREGDTIRRTGKIMEVPVGES
                     LIGRVVDPLGRPVDGLGEIHTDKTRPVEAPAPGVMQRKSVSEPLQTGLKAIDALVPIG
                     RGQRELIIGDRQTGKTTIAIDTILNQKDQDMICIYVAIGQKESTVRTQVETLRQYGAL
                     DYTIVVTASASQPSPLLFLAPYTGVAMAEEFMYQGKHVLIVYDDLSKQAVAYRELSLL
                     LRRPPGREAFPGDVFYLHSRLLERSAKVSDELGGGSITALPFIETQAGDISAYIATNV
                     ISITDGQIFLGDGLFNAGIRPAIDAGSSVSRVGGSAQIKAMKKVAGTLRIDLASYREL
                     EAFTKFGSDLDAATQAKLNRGRRTVEVLKQPVHKPLPVEKQVTILYALTHGFLDTVPV
                     DDIVRFEEEFHTFFDAQHPEILETIRDTKDLPEEAVLDAAITEFLNQSSFQ"
     gene            60745..61623
                     /locus_tag="VYO11_000165"
     CDS             60745..61623
                     /locus_tag="VYO11_000165"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002895995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HEV1594794.1"
                     /translation="MAVSLNDIKTKIASTKNTSQITNAMQMVSAAKLGRSEEAARNFQ
                     VYAQKVRKLLTDILHGNGAGASTNPMLISRSVKKTGYIVITSDRGLVGGYNSSILKAV
                     MELKEEYHPDGKGFEMICIGGMGADFFKARGIQPLYELRGLADQPSFDQVRKIISKTV
                     EMYQNELFDELYVCYNHHVNTLTSQMRVEQMLPIVDLDPNEADEEYSLTFELETSREE
                     ILEQLLPQFAESMIYGAIIDAKTAENAAGMTAMQTATDNAKKVINDLTIQYNRARQAA
                     ITQEITEIVAGASALE"
     gene            61709..63115
                     /gene="atpD"
                     /locus_tag="VYO11_000166"
     CDS             61709..63115
                     /gene="atpD"
                     /locus_tag="VYO11_000166"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HEV1594795.1"
                     /translation="MSSGKIAQVIGPVVDVLFAAGEKLPEINNALVVYKNDERKTKIV
                     LEVALELGDGMVRTIAMESTDGLTRGMEVLDTGRPISVPVGKETLGRVFNVLGDTIDL
                     EAPFTEDAERQPIHKKAPTFDELSTSSEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYWEMKESGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSVTSIQAIYVPADDYTDPAPATAFAHLDSTTNLERKLVQ
                     LGIYPAVDPLASSSRALAPEIVGEEHYAVAAEVKRVLQRYHELQDIIAILGMDELSDE
                     EKTLVARARRIQFFLSQNFNVAEQFTGQPGSYVPVAETVRGFKEILDGKYDHLPEDAF
                     RGVGSIEDVIAKAEKMGF"
     gene            63126..63545
                     /locus_tag="VYO11_000167"
     CDS             63126..63545
                     /locus_tag="VYO11_000167"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HEV1594796.1"
                     /translation="MAQLTVQIVTPDGLVYDHHASYVSVRTLDGEMGILPRHENMIAV
                     LAVDEVKVKRIDDKDHVNWIAVNGGVIEIANDMITIVADSAERARDIDISRAERAKLR
                     AERAIEEAQDKHLIDQERRAKIALQRAINRINVGNRL"
     gene            complement(63590..64603)
                     /locus_tag="VYO11_000168"
     CDS             complement(63590..64603)
                     /locus_tag="VYO11_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HEV1594797.1"
                     /translation="MKETVYFGTYTRRTSQGIYKADFDTETGQLSNLELFAAEPSPTY
                     LAFDQHQHLYTVGSQDDKGGIAAYQTDGTVLNHVVEEGAPHCYVAVDEKRDLVYAANY
                     HKGQVLVYKRQEDGSLLLSDMDQHSGQGPHENQASPHVHYTDLTPDHYLVTCDLGTDQ
                     VITYDLDQEGKLSKLYTYHSKPGAGSRHIIFHNHYKIAYLICELNSTIEVLIYDGVGE
                     FERMQVISTLPEAYEGFNGTAAIHLSKDGKYLYASNRGHDSIAVYTILADGSLELLEI
                     VPTHGQTPRDFDLTPDQKFLIVVHQDSDNATVFKRNCDNGRLAELSNDFHVPEAVCIR
                     FAP"
     gene            64747..65913
                     /locus_tag="VYO11_000169"
     CDS             64747..65913
                     /locus_tag="VYO11_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEV1594798.1"
                     /translation="MEQKEKHFSLSWFFKWFLDNKAITVFLVTLLLGLNLFILSKISF
                     LFSPVLDFLAVVMLPVILSGLLYYLLNPIVDWMEKHKVNRVIAITIVFVIIALFIIWG
                     LAVAIPNLQRQVLTFARNVPVYLEDIDRIVNGLVAQHLPDDFRPQLEQVLTNFSSQAT
                     VLASKVSSQAVNWVSAFISGASQVIVALIIVPFMLFYLLRDGKGLRNYLTQFIPRKLK
                     EPVGQVLSDVNQQLSNYVRGQVTVAIIVAVMFIIFFKIIGLRYAVTLGVTAGILNLVP
                     YLGSFLAMLPALVLGLIAGPVMLLKVVIVFIVEQTIEGRFVSPLILGSQLNIHPINVL
                     FVLLTSGSMFGIWGVLLGIPVYASAKVVISAIFEWYKVVSGLYELEGEEVKSEQ"
     gene            65903..67132
                     /locus_tag="VYO11_000170"
     CDS             65903..67132
                     /locus_tag="VYO11_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HEV1594799.1"
                     /translation="MNNSQQMLQALEEQDLTKAEHYFAKALENDSSDLLYELATYLEG
                     IGFYPQAKEIYLKIVEDFPEVHLNLAAIASEDGQIEEAFTYLEEIQADSDWYVSSLAL
                     KADLYQLEGLTDVAREKLLEALTYSEDSLLILGLAELDSELENYQAAIQAYAQLDNRS
                     IYEQTGISTYQRIGFAYAQLGKFETATEFLEKALELEYDDLTAFELASLYFDQEEYQK
                     ATLYFKQLDTISPDFEGYEYGYSQALHKEHQVQEALRIAKQGLEKNPFETRLLLAASQ
                     FSYELHDASGAENYLLTAKEDAEDTEEILLRLATIYLEQERYEDILDLQSEEPENLLT
                     KWMIARSYQEMDDLDTAYEHYQELTGDLKDNPEFLEHYIYLLRELGHFEEAKVHAHTY
                     LKLVPDDVQMQELFERL"
     gene            67278..67919
                     /locus_tag="VYO11_000171"
     CDS             67278..67919
                     /locus_tag="VYO11_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV1594800.1"
                     /translation="MSYLFEILPSLLNGASTTVQVFALVLLFSIPLGVLIAFALQVHW
                     KPLHYLINIYIWVMRGTPLLLQLIFIYYVLPSIGIRLDRLPAAIIAFVLNYAAYFAEI
                     FRGGIDTIPRGQYEAAKVLKFSPFDRVRYIILPQVTKIVLPSVFNEVMSLVKDTSLVY
                     ALGISDLILASRTAANRDASLVPMFLAGAIYLILIGIVTIISKKVEKKYSYYR"
     gene            67929..68558
                     /locus_tag="VYO11_000172"
     CDS             67929..68558
                     /locus_tag="VYO11_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000891751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV1594801.1"
                     /translation="MLELRNINKVFGDKQILSDFSLSIPEKQILAIVGPSGGGKTTLL
                     RMLAGLETIDSGQIFYNGQPLELDELQKRNLLGFVFQDFQLFPHLSVLENLTLSPVKT
                     MGMKQEEAEKKASGLLEQLGLGGHAEAYPFSLSGGQKQRVALARAMMIDPEIIGYDEP
                     TSALDPELRLEVEKLILQNRELGMTQIVVTHDLQFAENIADVLLKVEPK"
     gene            68571..69407
                     /locus_tag="VYO11_000173"
     CDS             68571..69407
                     /locus_tag="VYO11_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV1594802.1"
                     /translation="MKKWMLVLVSLMTALFLVACGKNSSETSGDNWSKYQSNKSITIG
                     FDSTFVPMGFAQKDGSYAGFDIDLATAVFEKYGITVNWQPIDWDLKEAELTKGTIDLI
                     WNGYSATDERREKVAFSNSYMKNEQVLVTKKSSGITTAKDMTGKTLGAQAGSSGYADF
                     EANPEILKNIVANKEANQYQTFNEALIDLKNDRIDGLLIDRVYANYYLEAEGVLNDYN
                     VFTVGLETEAFAVGARKEDTTLVKKINEAFSSLYKDGKFQEISQKWFGEDVATKEVKE
                     GQ"
     gene            complement(69685..70032)
                     /locus_tag="VYO11_000174"
     CDS             complement(69685..70032)
                     /locus_tag="VYO11_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HEV1594803.1"
                     /translation="MEQFLDNIKDLEVTTVVRAQEALDKKETATFFIGRKTCPYCRKF
                     ADTLSGVVAETKAHIYFINSEEPSQLNDLQAFRSRYGIPTVPGFVHITDGQINVRCDS
                     SMSAQEIKDFAGL"
     gene            complement(70143..71861)
                     /locus_tag="VYO11_000175"
     CDS             complement(70143..71861)
                     /locus_tag="VYO11_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HEV1594804.1"
                     /translation="MSYQENYQKWVDFVELPDYLRQDLENMDEKTKEDAFYTNLEFGT
                     AGMRGLVGAGTNRINIYVVRQATEGLARLIESKGGNEKERGVAIAYDSRHFSPEFAFE
                     SAAVLAKHGIKSYVFESLRPTPELSFAVRHLNCFAGIMVTASHNPAPFNGYKVYGEDG
                     GQMPPHDADALTTYIRAIENPFAVEVADVETEKASGLIEVIGEAVDIEYLKEVKDINI
                     NPALIEEFGKDMKIVYTPLHGTGEMLARRALAQAGFDSVQVVEAQATADPDFSTVTSP
                     NPESQAAFALAEELGRQVGADVLVATDPDADRVGVEVLQKDGSYLNLSGNQIGAIMAK
                     YILEAHKNAGTLPENAALCKSIVSTDLVTKIAESYGATMFNVLTGFKFIAEKIQEFEE
                     KHNHTYMMGFEESFGYLIKPFVRDKDAIQAVLVVAELAAYYRSRGLTLADGIEEIYKE
                     YGYYAEKTISVTLSGVDGAEQIKAIMAKFRNNAPKEWNETAITVVEDFKAQTATVADG
                     TVTNLTTPPSDVLKYTLADGSWIAVRPSGTEPKIKFYIAVVGETNEESQAKIANIEAE
                     INAFVK"
     gene            72095..72238
                     /locus_tag="VYO11_000176"
     CDS             72095..72238
                     /locus_tag="VYO11_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tnpB"
                     /protein_id="HEV1594805.1"
                     /translation="MAYSTDFKQRALDYIKEGHSHVEAAKFFGVGVRTLFTWEKKDVN
                     KDT"
     gene            72205..72420
                     /locus_tag="VYO11_000177"
     CDS             72205..72420
                     /locus_tag="VYO11_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV1594806.1"
                     /translation="MGKERCEQGHIERKKRVVKNRKIPLEELKAFVEAHPDAFLREIA
                     AHFDCAVPSVWAALKQIKVTLKKDDEL"
     gene            72407..72940
                     /locus_tag="VYO11_000178"
     CDS             72407..72940
                     /locus_tag="VYO11_000178"
                     /inference="COORDINATES: protein motif:HMM:NF024751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
                     /protein_id="HEV1594807.1"
                     /translation="MTSFKEQEPEKVAEFLDILDNLKNLPIVYIDETGIDRYLYRPYA
                     GAPRGEKVYEKISGRRFERTSIVAGQVDGEFIAPMIYKKSMTSDFFVEWFKTQLLPAL
                     KTPHVIVMGNASFHPKNILDELCIQDKHFFLPLPPYSPDLNPIEQAWAILKKKVTDLL
                     REVPTIFECLECFFKTR"
     gene            73280..73534
                     /locus_tag="VYO11_000179"
     CDS             73280..73534
                     /locus_tag="VYO11_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1594808.1"
                     /translation="MLNVDQDFMSISKSNKSGSDWKKTFTVRTTNRLANDLNNVLKQA
                     DKDTPNTPIWLNSAASKAKDDDRAYKLLKTLIPGENYLSC"
     gene            73645..74724
                     /locus_tag="VYO11_000180"
     CDS             73645..74724
                     /locus_tag="VYO11_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HEV1594809.1"
                     /translation="MNIILIAKPLRENTNTKANALNNGWARSGSEEFKKFSHFVGVDK
                     GIVRTNVLTGKKLSDKIRKEVDSGDSKLGKGGYFSTGDVLLGKDVVSYTVQVFSENNE
                     RVGVNTQSHRVQYNLPILADFSVIQDIVEPSRTVVEKIIPKLNIPEEEKKKKTSELAE
                     LISENVKVCYVDEQGRLLSLKNDTGIGEKESDGTYITNKKQLIGTSYNVTDKKLSSMT
                     TTDGKYYTFKEADTNSASLTGNIVSEGRTVTLVYRESEAPTTATVTANYYKEGSQEKL
                     AESVIKADLAIGSEYTTESKTIEGKTTTEDKEDRVITRKTTYTLVATPANAYQKTVQQ
                     LTITTVRMLRKQWFPKQQPLLRRRL"
     gene            74682..75359
                     /locus_tag="VYO11_000181"
     CDS             74682..75359
                     /locus_tag="VYO11_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEV1594810.1"
                     /translation="MVPKTATSTETKTITRIIHYVDKVTNQNVKEDVVQPVTLSRTKT
                     ENKVTGVVTYGEWTTGNWDEVISGKIDKYKDPDIPTVESQEVTSDSSDKEITVRYDRL
                     STPDKPTPEKPEIPSPQEPGTPGEPTPEKPIPQPNPEHPSVPTPNPELPNQETPIPEP
                     TPEPGTPKTETPVNPDPEVPTYETGKREELPNTGTEANATLASAGIMTLLASLVLGFF
                     KKKEDEK"
     gene            75583..76452
                     /locus_tag="VYO11_000182"
     CDS             75583..76452
                     /locus_tag="VYO11_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000348128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HEV1594811.1"
                     /translation="MDFTWALKYATEFLGTAILIILGNGAVANVELKGTKGHQSGWIV
                     IAVGYGMGVMIPALMFGNVSGNHINPAFTLGLAVSGLFPWAQVVPYIIAQVLGAIFGQ
                     ALVVATYRPFYLKTEKPNNILGTFSTISSIDHGTKESRYAATVNGLINEFVGSFVLFF
                     AALGLTKNFFGAEVLQFMKQKAIEAGQTVDFSDLAIKAQVAPHTASGLSVAHLALGFL
                     VMALVTSLGGPTGPALNPARDLGPRLLHAFLPKSVLGEHKGDSKWWYSWVPVVAPIAA
                     AIAAVAVFKFLYL"
     gene            77363..78559
                     /gene="tuf"
                     /locus_tag="VYO11_000183"
     CDS             77363..78559
                     /gene="tuf"
                     /locus_tag="VYO11_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HEV1594812.1"
                     /translation="MAKEKYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLARRLPSSV
                     NQPKDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQM
                     DGAILVVASTDGPMPQTREHILLSRQVGVKHLIVFMNKVDLVDDEELLELVEMEIRDL
                     LSEYDFPGDDLPVIQGSALKALEGDSKYEDIVMELMNTVDEYIPEPERDTDKPLLLPV
                     EDVFSITGRGTVASGRIDRGIVKVNDEIEIVGIKEETQKAVVTGVEMFRKQLDEGLAG
                     DNVGVLLRGVQRDEIERGQVIAKPGSINPHTKFKGEVYILTKEEGGRHTPFFNNYRPQ
                     FYFRTTDVTGSIELPAGTEMVMPGDNVTIDVELIHPIAVEQGTTFSIREGGRTVGSGM
                     VTEIEA"
     gene            78943..79374
                     /locus_tag="VYO11_000184"
                     /pseudo
     CDS             78943..79374
                     /locus_tag="VYO11_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix domain-containing
                     protein"
BASE COUNT        24256 a        14713 c        17588 g        22817 t
ORIGIN      
        1 tttgctcaaa aggggcaaaa aaggggcaaa agtgtcgtaa atctctgtaa aaggatgtaa
       61 aaacatttat ttaaaagctc aaaatatagc tgttttaaaa ggtattgtaa gatatagtaa
      121 aacgatgtaa aggtattttt aaatgcggat gaattataaa accacgaatc ctatgtgact
      181 cgtggttctt ttttataaac tggtagagtg ttttggttgt actttttgtt cagggtcaat
      241 gtagttgata gcgttgttga cagcagttgg agcttctccg aggcctgtcg caatcagatc
      301 aatttttccg tcatagtagc agcagtcacc gatagcatag atacctgctt ggctggattc
      361 ctgtttgctg ttgacgataa tcttgtgacg gttgaggtcg agcccccagt ttttaaggtt
      421 accgacagaa gatttgaaac catagttgac aaagaggtgg tctaggtcaa tggtttcagt
      481 ttcatcagat ttgacttttg tgatttcaag tttatcaagt gtttttccat ttccaaggag
      541 ttggctaggg gcgaatggtg tcttgatggt tacagatgat tcttgcaagg cttgaacact
      601 gtgttccaag gcacggaaat tatctctgcg gtgaacaagg gtagttggtg cgattttttc
      661 aaaagccaaa gcccaatcca cagccgagtc tcccccacca agaatcgtca ctttcttacc
      721 agcgtattgc tgaatgttag aaacgtggta gtggatattt tcatagccct caacaccttc
      781 aagttccagc ggacgtggtt tgaaggcacc gccacccata gcgatgatga ctgttttagt
      841 caggtgactt cctttagaag ttgtgatggc aaattcttct tcttgtttgt caatctcaag
      901 aaccgtttca ttgagatgaa taggggtatc aaatccattt agctgttcaa tcaagcggtt
      961 agtcaactct tctccagtca ggtttgggaa gcctggtacg tctaggattt ccttttcagg
     1021 gtagagaata gcaggttgtc cacctagctg gggaagagag tcgatgattt gaaccttggc
     1081 ttggcgtagg tgggcataaa aggctgcaaa aagcccgaca ggaccaccac ccacaatggt
     1141 aatatcatag agttgagaca tagtttctcc tttgtttttt ctagtcagtt tattttatca
     1201 tatttttgtt caatgtaaaa tggactagga tagggaaaaa aatgccagaa aatggtataa
     1261 taggacgaaa gtgttttgat agggaggata tcagggatga attttcaaca attatccaat
     1321 ctgcaatatt ggaccagttt gtttgcaagt ccatggacga tagctatcaa tctgattgat
     1381 attttgattg ttgcttatat tttataccat tttacaaaag ctattgcagg aaccaagatt
     1441 atgattttgg tacgtggagt tttggtgttt attttagctc aaatccttgc aaatatgatt
     1501 ggtttgacta cgatttcttg gttaatcaat caaattatta cttatggggt tattgcggcg
     1561 gttgttatct tctctccaga gattcggact ggtttggaac gtttgggaag agcgacagat
     1621 ttcttttcca atgcccctat tagtgctgag gaacagatga ttcgtgcctt tgttaagtct
     1681 gttgaataca tgagtcctcg taaaatcggg gccttggttg ctattcagcg tgtacgtacc
     1741 ttgcaggagt atatttcgac aggaattccc ttggatgcta agatttctgc agaacttctc
     1801 attaacattt ttattcccaa cactccccta catgatggtg cggtgattat caaagaagaa
     1861 cgtatcgctg tgacgtctgc ctatctgccc ttgacaaaaa acacagggat ttccaaggaa
     1921 tttgggacca gacaccgggc ggctatcggt ttatcagaag tctcagatgc cttgactttt
     1981 gtcgtatcag aggaaacggg aggaatttcg ataacctata atggaaggtt taagcacaac
     2041 ctaacacttg atgaatttga aacagaatta cgtgaaatct tacttccaaa agaggaagtg
     2101 ggtcttagtt ttaaagaacg attgctagga ggatggaaac atgaaaaaaa atagtttata
     2161 tatcatatcc tcactctttt ttgcttgtgt cttatttgtc tatgctacgg cgacgaattt
     2221 tcaaaacagt accagtgcta ggcaggtaaa aacggaaacc tatactaata cagtaacaaa
     2281 tgtccctatt gacatacgct ataatagtga taagtatttt attagcggtt ttgcttcaga
     2341 agtatcagtg gtcttgactg gtgcaaatcg cctatcgcta gctagtgaaa tgcaagaaag
     2401 tacacgtaaa ttcaaggtta ctgctgacct aacagatgcc ggtgttggaa cgattgaagt
     2461 tcctttgagc attgaagatt tacccaatgg gctgaccgct gtggcgactc cgcaaaaaat
     2521 tacagtcaag attggtaaga aggctcagaa ggataaggta aagattgtac cagagattga
     2581 ccctagtcaa attgatagtc gggtacaaat tgaaaatgtc atggtgtcag ataaagaagt
     2641 gtctattacg agtgaccaag agacattgga tagaattgat aagattatcg ctgtcttgcc
     2701 aactagcgaa cgcataacag gtaattacag tggttcagta cctttgcagg caatcgatcg
     2761 caatggtgtt gtcttaccgg cagttatcac tccgtttgat acaataatga aggtgactac
     2821 aaaaccagta gcaccaagtt caagcacatc aaattcaagt acaagcagtt catcggagac
     2881 atcttcgtca acgaaagcaa ctagttcaaa aacgaattaa aaatagaaaa ggattttata
     2941 acaatgggta aatattttgg gactgatgga gtccgtggag aagctaacct agaactaaca
     3001 ccagaattag cctttaaact aggacgtttt ggaggctatg ttcttagtca acatgaaacg
     3061 gaagcgccga aagtctttgt aggacgtgac acacgtattt caggggaaat gctggaatcg
     3121 gccttggtgg caggtctcct ttcagtaggg attcacgtat acaaacttgg tgtccttgca
     3181 acaccagcag tagcttactt ggttgaaact gaaggagcaa gtgccggtgt catgatttct
     3241 gctagccaca acccagccct tgataacgga atcaagttct ttggcggtga tggcttcaaa
     3301 ctagatgatg aaaaagaagc agaaattgaa gccttgctag atgctgagga agacactctt
     3361 cctcgtccaa gtgcagaagg cttaggaatt ttggtagatt atccagaagg cttgcgtaag
     3421 tatgaaggat accttgtttc aactggaact cctcttgatg gaatgaaggt tgccttggat
     3481 acagctaatg gagcagcttc taccagtgcc cgtcaaatct ttgcagacct tggtgcccaa
     3541 ttgacggtta tcggggaaac accagacggt cttaacatca accttaatgt tggttcaaca
     3601 catccagaag cccttcaaga agtggtcaaa gaaagtgggt cagctattgg tttggccttt
     3661 gatggagaca gtgaccgctt gattgctgtt gatgagaatg gtgacatcgt cgatggtgac
     3721 aagattatgt acatcatcgg aaaatacctt tctgaaaaag gacaattggc tcaaaataca
     3781 attgtgacaa ctgttatgtc taaccttggt ttccacaagg ccttgaatcg cgaaggtatt
     3841 aacaaggcag ttactgcagt tggtgaccgc tacgttgttg aagaaatgag aaaatcaggc
     3901 tacaaccttg gtggtgaaca gtctggtcac gttatcttga tggattacaa taccacaggt
     3961 gatggtcaat tatcagcagt tcaattgact aaaattatga aggaaactgg taagagctta
     4021 tcagagttgg cggcagaagt aacgatttat ccacaaaaat tagttaatat ccgagtggaa
     4081 aacgtcatga aggaaaaggc catggaagtg ccagctatca aggccatcat cgagaagatg
     4141 gaagaagaaa tggcggggaa cggccgtatc cttgttcgtc caagtggaac agagcccctc
     4201 ttgcgtgtta tggcagaagc gcctacaaca gaagaagtgg actactatgt tgataccatc
     4261 acagatgtag ttcgtgctga aattgggatt gactaaatcc tagaaaacta gatgaaaata
     4321 aaaaattatg gtacaatagc ttataatatt gtagccgatg gagaaagaca tgaatcttaa
     4381 acgtgaacaa gaatttgtta gtcagtatca ttttgatgca cgtaattttg aatgggaaaa
     4441 tgaaaatgga gctcctgaaa ccaaggtgga tgtgaatttc caattgctcc aacatgacca
     4501 agaaaatcaa gtgacttcct tgattgtcat cttgagcttt atgattgtat ttgataagtt
     4561 tgtcattagt ggaacaatct cacaagtaaa ccatatcgat ggccgtattg tcaatgaacc
     4621 aagtgaattg aaccaagaag aggtggaaac cttggctcgt ccatgtttga acatgctcaa
     4681 tcgtttgact tacgaagtga ctgaaattgc attagactta ccaggaatta atttggagtt
     4741 ctaatatgaa attagctgtt ttcacagatt cctctgctta tctcagtgaa gagaccttgc
     4801 aaagagaaga cttgtttgtc ttggatattc ctgtcaatat tgatggtgag gaatatgtcg
     4861 aaggcatcaa tctgtctgct gaggaatttt accaaaaaat ggctcaggct tctgaattgc
     4921 ctaagaccag tcaaccaagt attgccaagt tagatgagat cttaacttcg ctcaaagaac
     4981 aaggctatac acatgccttg gggcttttcc tatcttctgg aatttcaggt ttttaccaaa
     5041 atatccagta tatggtcgat gactatgagg gcttaaccat tgctttccca gacactttga
     5101 ttacaagtgc tcccctaggc atcatggttg aaagcgtctt taattggcgt gatcagggcg
     5161 atgattttgc cagcattcag gataagctag ccattcaaat cagccgtacg tcagccttta
     5221 tcatggtaga tgacttggat catttggtaa aaggtggacg cctttcaaat ggggctgcca
     5281 ttttgggcaa tttgcttagc attaagccaa tcctttattt taacgatcaa ggtgtgattg
     5341 aagtttacga aaaagttcgt actgaaaaga aggccaccaa gcgcttaatt gaaattatca
     5401 aggaaacaac ggcttcaggt caataccggg tcattgtcat tcatgggaat gctcctgaaa
     5461 aggctgaaga attgcgtcag cacttgcttg attttggctt gggttcggat gtttcacttg
     5521 ctacatttgg tagtgtcatt ggaacgcacc taggagcagg aagtattgct ctgggttata
     5581 ttccagtgat ttagttggcg cttctaggct agttaagatg ccttgtatct tagaaattga
     5641 acacggacta cctgcctctt gaaaaaagat gcctgtcttg cctttcgtgg aaagtcagtg
     5701 ccattcccta tttttcagag gcagctaagg tcctttgtat cttgataatt gaacacgcct
     5761 ggaaccctgt gtgaaaaaga tagttcttcc aagaagtaga cacttcttga ttggaattcc
     5821 tattttcact ttgtgttctt acggactttg tatcttagac aggagtagag atgagtattc
     5881 gagtaattat tgccggtttt aagggaaaga tgggccaggc tgcttgtcag atggtattga
     5941 ctgatccaga cttggacttg gtggcagttt tggatccttt tgagtctgag tcagaatggc
     6001 agggtattcc tgttttcaag gataaggctg atttagctgg ttttgaagcg gatgtctggg
     6061 tagattttac tactccagct gttgcctacg aaaatacacg ttttgctctt gaaaatggct
     6121 ttgctccagt agttggaacg actggtttca cgagtgaaga aattgcagag ctaaaagaat
     6181 tttctcgtgc ccaagacttg ggtggcctga ttgcccctaa ctttgccttg ggtgctgtct
     6241 tactcatgca atttgcgacg caggctgcca aatatttccc aaatgtggag attattgagc
     6301 tccatcatga caagaaaaag gatgctccga gtggaacagc cattaaaaca gctgagttga
     6361 tggcagaggt tcgagagtcc attcagcaag gcgcagcaga tgaggaagag ctgattgctg
     6421 gtgctcgtgg tgctgacttt gatggtatgc gcatccactc agttcgtttg ccaggcttgg
     6481 tagctcatca ggaagtcatc tttggcaatc agggagaagg gctgaccctc cgtcatgact
     6541 cctatgatcg catctccttc atgacaggag tcaatttggg aattaaagaa gttgtcaagc
     6601 gtcatgagct tgtctatgga ttagaacact tattatgaga ttaacgcaaa tgccttctga
     6661 atttcagaag gctttaccag tattagaaaa aattaaagaa gcaggctttg aggcttattt
     6721 tgttgggggc tctgttcgag atgcccttct ccatagccct atccacgatg tggatattgc
     6781 gacgtcttct tatccagaag agaccaagca gatttttccg cgaacagccg atatcggaat
     6841 cgagcatgga accgtcttgg tcttagatgg ggatgaggag tatgaggtaa caacctttcg
     6901 gacagaggat gtctatgtgg actatcgcag acccagtgcg gtttcctttg tgcgctcgct
     6961 agaagaagac ctcaaacgcc gtgatttcac agtcaacgcc tttgccttgg atgagacagg
     7021 agaaatcgtt gacttgttcc atggtttaga agatttggaa aagcaagtct tgcgagcagt
     7081 tggagtggct agtgagcgtt tcaacgaaga tgctttacgg attatgcgtg gtttccgttt
     7141 tcaggctagt cttggttttg cacttgaacc agaaacattt aaagctatga agaccttgac
     7201 gccgcttttg gagaaaattt ctgtagagcg taccttcgtc gagtttgata aactcttgct
     7261 ggctccattt tggagaaggg gcttggcttc catgattgag agtcaagctt atgactatct
     7321 ccctgatatg gcatctagcc aggacaagct caacagactg tttgatttgg agactgattt
     7381 tacttttgaa tcctctgaac aagcctgggc ggctttacta tgggctttgg agattgaaaa
     7441 tgcgcagtca tttttgaaat cttggaagac ctcacgccag tttgccaagc aagttcagga
     7501 tttgctgatt attttggctc tgcgtgaaaa tggagaattg agcaagcgag attgttatcg
     7561 ctttgacata gatttgcttt tacaggctga aaatcttcgt caagctcaag gaaaagaagt
     7621 caacccacaa gccatcacag aaaaatacca aagcttgact atccatgaca agaaagagat
     7681 tcagattaat ggcggtattt tgatcaagga atatggctat cagccaggcc cagacttggg
     7741 agagatttta acagagattg agtttgccat tgtcgatgga gaattggaga ataatcgtga
     7801 agccatccat gcttacctga gggagaaaaa atgagtgatt ttatcgttga aaaactaagt
     7861 aaatccgttg gtgacaagac cgtttttagg gatatttcct ttattatcca tgacttagac
     7921 agaattggtt taatcggtgt caatgggact ggcaagacca cccttttgga cgtcctttct
     7981 ggtgtttctg gatttgatgg ggatgtcagt cctttttcag ctaaaaatga ttaccagatt
     8041 ggttacttga ctcaggatcc tgattttgat gatagaaaga cagttttgga tacggttcta
     8101 tctagtgaac tcaaggaaat ccagctcatt cgtgagtatg aattgattat gctcgactat
     8161 agtgaggaca agcaggcgcg tttggaacgt gtcatggcag agatggactc tctccaagct
     8221 tgggaaatcg aaagtcaggt caagaccgtt cttagcaaat tgggcattca agacttatct
     8281 actcctgttg gggaattgtc aggtggtctg agaagacggg tacagttggc acaagtctta
     8341 cttggcaacc acgacctctt gcttttggat gagccgacca accatctgga tattgcgatt
     8401 attgagtggc tgaccctctt tttgaaaaat tctaagaaga ccgtcctttt tatcactcac
     8461 gatcgttatt tcttagacgc tttgtcaaca cggattttcg agttggatcg tgcaggcttg
     8521 accgagtacc agggaaatta ccaggactat gttcgcctaa aggcggaaca ggatgagcgc
     8581 gacgcggctc ttcttcacaa aaaagaacaa ctctacaaac aagaattggc ctggatgcgc
     8641 agacaaccgc aggcgcgtgc gaccaagcag caggcccgta tcaatcgatt ccatgatctg
     8701 aaaaaggaag tttcaggcag tagtgctgag acagacttga ccatgaactt tgaaaccagt
     8761 cggattggga agaaagtcat cgagtttcag gctgtttcct ttgcctatga aaacaagcct
     8821 attttgcaag attttaatct cttggtgcag gccaaagacc gtatcggaat cgttggggac
     8881 aatggtgttg gaaaatcaac cctgctcaac ttgattgcag gaagtcttga gccaactaaa
     8941 ggacaagttg tgattgggga aactgttcgc atcgcctatt tctctcagca aattgagggt
     9001 ttggatgaaa gcaagagagt tatcaattac ctgcaggaag tggcagagga ggtcaagacc
     9061 agtggcggtt ctacgacttc gattgcagag ttgctggagc agttcctttt cccacgttcg
     9121 acgcatggaa ccttgattgg gaaattgtca gggggtgaga aaaaacgtct ttatctcctc
     9181 aaactgcttt tggaaaaacc aaatgttctt cttttagacg agccaaccaa tgacctagat
     9241 attgcaactt tgacagtctt agagaatttc ttgcaaggtt ttgcaggtcc cgttttaaca
     9301 gtcagtcacg accgctattt cttggataag gtagcgacca agattctcgc ttttgaggat
     9361 ggcaagattc gtcctttctt tggtcattac accgactatc ttgatgaaaa agcttttgaa
     9421 acagatatgg tcaatcaagt gcaaaaggtc gaaaaggaaa aagtggtcaa ggttcgagaa
     9481 gacaagaaac gcatgaccta ccaagaaaag caggagtggg caagtattga aggtgatatt
     9541 gaaaccttgg aaaaacgtat cgctgctatt gaagaggaaa tgcaggctaa cggctctgac
     9601 tttggtaagc tggctactct ccaaaaagaa ttggatgaga aaaatgaagc actccttgaa
     9661 aaatacgaac gctatgagta tctcagtgaa tttgatagtt aagactattc gaaaatcaaa
     9721 gtgcaaacta tgtcggcttc acattgccga ctcaagtaca gcctgtgacc ggcttcctaa
     9781 tttgcacttt gatttttatt gagtataaac gaatagaaaa atcccgtctc atgaaaggat
     9841 ttctctattc ttttttggtt tcttgatgaa agatattttg ccaggtttcg tggcgacgcc
     9901 agatactggt atggatgata ccatctaact catagcagat aagtttggtt ttttgactga
     9961 tggaagtaat ttgaatgtcc ttgatagcag aatttaactc ttttttggtc ttataagcct
    10021 ctttatccat ctgctctcca tcttggcgaa tatagacaaa atcatcagtc aagagttctt
    10081 ctagttggtt tccttggtcg atcaattgtt cacgcataag caatttttta tagacattgt
    10141 ctaaaatttc atcctcaggg ataggtgctg gttcgatatg gacatcggta tcaaagacgc
    10201 caaaacgatt ctccagcata gactcgacct gatccgcgat ttcatggctt tcaaaaacag
    10261 acaagtcagg attcatctct agtgtaatat ccaggtagat gttgctaccg taggtgcgac
    10321 ctctttgcga tttgaccttg ctgattttgg gaatttccat gatagccttt tggtagtcct
    10381 cgagcaggcg gtcgtcaaag ccatctgaaa gactaaagga agactcgatg aagatatcat
    10441 aggcagtctt caagataaag aaagtgatga tgatagcaac cagtttatcc acaatcggat
    10501 aattgaaact actagctagg atggcaatgg cggttccaag tgaggtaaca gcgtcagaaa
    10561 gattgtcctt agcagctgcc ttcagcgcct tggagttgga tttcttactg aggcgagtat
    10621 tgtagagata gaccacaaac ataatcgctg cagaaatgat tcctagagtt gcaccaagag
    10681 gatcaatgac cgtttcttcc cgactgagaa tcttttgaat ggtatctctt agaacatcga
    10741 aaccgacata gaacatgatg atagaagtga tcaagcttgc caaatcttca atcttccaat
    10801 gaccaaaacg gtggtcacgg tctgcaggct ggcgcgccat ccgaatcccg attaagaggg
    10861 ccacatttcc aatgatgtcc gatacgttat taaaaccatc ggccaccaaa ctggatgaat
    10921 gaaggagatg accagttgct aatttggctg cagacaagat caaataggtc gaaatactga
    10981 taatggctcc acgctcggct aacttgagat ttgagataga ttgcttcatt caacttcctt
    11041 tctagtcaca tagcattcta ccattatact ggttttcaag gaaaaattca aataaggcag
    11101 tttttattct ttgaaaactc cccaaaattt ggtataatgg tactactcaa gggagtagct
    11161 ggcagaaacc tgtgatagtg tcgtcattcc gaattttatg ctgaaaagta tgctttccgg
    11221 ccctatctta aacagcgaga cttgttatga ttaacaggtc tctttttgtt tgtcgtgaaa
    11281 agatatgaca gaaagagagt ctgttttgca cacaatgtca aggaggagac acatgtcaaa
    11341 agaacaaaaa cgccaagcgt tttatactca gagccctgaa gaggtcttgc aggctgtgga
    11401 tgcgaccgag caaggtttgt catcaagtga ggcggaaaag cgccttgccg aatttgggca
    11461 caatgaactc gaagaaggcg agaaacgatc aatcttggtc aaattcatcg agcaatttaa
    11521 ggatttgatg attatcatcc tagttgcggc agcaatcttg tcagtcgtga cttctggtgg
    11581 ggaagatatc gcagatgcca ttatcatcct agctgtggtt atcatcaacg ctgcctttgg
    11641 tgtttaccaa gaaggaaaag ctgaagaagc tattgaagcc ctcaaatcca tgtctagtcc
    11701 agttgcccgc gttcttcgtg atggacacat ggcagagatt gactctaaag aattggtacc
    11761 aggcgatatc gttgcccttg aagcaggtga cgtggtacca gcggacctac gtttgataga
    11821 agccaactct cttaaaattg aagaagcagc cttgacaggt gaatctgtac cagtcgaaaa
    11881 agacttgtca gtcgagcttg cgacagatgc tggtattggt gaccgtgtca acatggcctt
    11941 ccaaaactca aacgtaacct atggtcgtgg gatgggtgtt gttgtcaata caggtatgta
    12001 cactgaagtt ggtcatattg ctggtatgct tcaagatgcg gatgagactg atacaccact
    12061 caaacaaaac ttgaacaacc tttctaaggt cttgacctat gctatcttgg tcattgccct
    12121 tgttactttt gtagtgggtg tcttcattca agggaaaaat ccacttggtg agttgttgac
    12181 ttctgttgcc cttgccgttg cagccattcc agaaggactt cctgctatcg ttaccatcgt
    12241 tctttctctt ggtactcaag ttttggccaa acgacattcc atcgttcgta agttgccagc
    12301 agttgaaaca cttggttcaa ctgaaatcat cgcttctgat aagactggta cgctgactat
    12361 gaacaagatg acagtcgaaa aagtcttcta cgatgcggtt ctacatgact cagctgatga
    12421 tattgaacta ggtcttgaaa tgccactact tcgttcagtt gtcttggcca atgatacgaa
    12481 aatcgatgtg gaaggtaact tgattggtga cccaaccgaa acagccttta tccaatatgc
    12541 cttggacaag ggctatgatg tcaaaggttt cttagagaaa tatcctcgtg tagctgaatt
    12601 gccatttgac tctgaccgta agctcatgtc aacagttcac ccattgccag atggtcgttt
    12661 ccttgtagca gtcaagggtg cgccagacca actcttaaaa cgttgtcttc ttcgtgataa
    12721 ggctggggat attgctccga ttgatgagaa ggttacaaat ctcattcata caaacaattc
    12781 tgaaatggct catcaagcct tgcgtgtcct tgcaggtgct tataagatta tcgatagtat
    12841 tccagaaaat ctcacttctg aagagcttga aaatgattta atttttactg gtttgattgg
    12901 gatgattgac cctgaacgtc ctgaagccgc tgaggctgtt cgtgtggcta aggaagcggg
    12961 aatccgtcca attatgatta caggtgacca ccaagacaca gcggaagcca ttgccaaacg
    13021 tttgggaatc attgacgcaa acgatacaga aggtcacgtt ttaactggtg ctgaactcaa
    13081 tgaactgtca gatgaagaat ttgaaaaagt cgttggtcaa tactctgttt atgcccgtgt
    13141 gtctccagaa cacaaggttc gtatcgtcaa ggcttggcaa aaacaaggta aagtcgttgc
    13201 catgacaggt gacggtgtca atgacgcgcc agctctgaaa acagccgata tcggtatcgg
    13261 tatgggaatc actggtacag aggtttctaa gggggcttct gatatgattc ttgcagatga
    13321 taactttgcg actattatcg tcgcagtgga agaaggacgt aaggtcttct caaacattca
    13381 aaagactatt cagtacctac tttctgctaa tactgctgaa gtattaacca tcttcctatc
    13441 aaccttgttt ggttgggatg tcttacagcc ggttcatctt ttgtggatca acttggtaac
    13501 ggataccttc ccagctatcg ctcttggtgt tgaacctgcg gaacctggtg tcatgaatca
    13561 taaaccacgt ggacgcaagg caagcttctt ctcaggtggt gttttgagtt ctatcattta
    13621 tcaaggtgta ctccaagcag ctcttgttat gagtgtttat ggccttgcga ttgcttaccc
    13681 agttcatgtg ggtgacaatc atgctattca tgcagatgcc ttaacgatgg cctttgcaac
    13741 ccttggtttg attcagctct tccatgccta caatgtcaag tctgtctacc aatccatctt
    13801 gacagttggc ccattcaagt ctaagacctt taactggtcc atcttggtat cctttatcct
    13861 tctcatggca acaatcgttg tagaaccgct tgaaggaatc ttccacgtaa ccaaactaga
    13921 cttgtcacaa tggggaattg ttatggctgg aagcttctca atgattatca tcgtcgaaat
    13981 cgttaagttt attcaacgca aactcggttt tgacaagaat gcgatttaag ggaggtttcg
    14041 gatgtcagca tatcaattac cgaccgtatg gcaggatgaa gctagtaatc aaggagcttt
    14101 tacggggcta aacagaccaa cagcaggtgc ccgtttcgaa caaaacttgc caaaaggaga
    14161 acaagctttt cagctttatt cactgggaac accaaatggt gtgaaggtta ctatcttatt
    14221 ggaagaatta ctagaagctg gttttaagga agcggcttac gacttgtata agattgctat
    14281 catggatggg gatcaattcg gctcagactt tgtgaagctc aatccaaatt ccaagattcc
    14341 agccttattg gaccagtcag gtactgaaaa cgtaagagtc tttgagtctg ctcatattct
    14401 tctttacctt gctgagaaat ttggagcctt tttaccaagt aatcctgtgg aaaaggtaga
    14461 agttttgaat tggctattct ggcaagcagg tgcagcacct tttctaggtg ggggatttgg
    14521 acatttcttc aattatgctc ctgaaaaatt ggaatatcct attaaccgtt ttacgatgga
    14581 agtgaaacgc cagttggatt tattggataa ggaattggct cagaaacctt atattgcagg
    14641 caatgactat acgattgcag atattgctat ctggtcttgg tatggacagt tagttcaagg
    14701 aaatctttac caaggttctg caaaattctt ggatgcctca agttatcaaa atctagtaaa
    14761 atgggcagaa aaaattgcca atcgtccagc tgttaagcgt ggcttggaag taacttatac
    14821 agaaattaaa tagcaaaaaa gtcatcttcg gatggctttt tgctacagtt gagggaaagg
    14881 gtttgcagct atcggctttt gtgctataat tgctataata tagtaaaaag caagaggagt
    14941 gtgaggaagt ggaaaagaaa attgtgaagg atatcttatt tttatctcaa gtgtctcagc
    15001 cggcaagtca ggaggacctt tatcttgcca gagatttgca ggatacactc ttagcaaatc
    15061 gtgatacctg tgttggtcta gctgccaata tgattggggt gcagaagcgc gtgattatct
    15121 ttaatcttgg cttggttccc gtggtcatgt ttaacccagt gcttctgtcc tttgaaggat
    15181 cctatgaggc agaagaaggc tgtttgtcct ttgtaggtgt gagatcaact aagcgttatg
    15241 aaaccacaag gcttgcctat cgtgacagca agtggcagga acagaccatt accttgacag
    15301 gcttcccagc tcagatttgc cagcatgagc tggatcactt ggaaggacga atcatttagg
    15361 aggaaagcaa atgaaacgaa tagtctttga acttattttt atcgcaacga cctggtatat
    15421 ctttttaccg ccccttaacc tgaccagctg ggaatttctc ttcttcctct gtgggcattt
    15481 gttagttgtg gcaatcttat ttggctttgg caaggggata aaccttgtca aaacggttca
    15541 tgtgcgccac ggtaaggcgg aagctgcctt aaatcttgag ggtttcaaaa tcaatcggtt
    15601 agggaaaatt ctgttagctt cgattggagg aattcttctc ttggcagctt tggtttcctt
    15661 ggtaacttcc agcatgtttc aggctaaaaa ttatgccaat gtagtcacgg ttacggaaaa
    15721 agactttact gaatttccta ggagtgacac cagtaaggtt cctatcctag atagaagtac
    15781 tgctgaaaaa attggagacc gctacttggg ttccctaacc gataaggtgt cgcaatacgt
    15841 agcggcagat acctataccc aattgacaat tgatgggaaa ccttatcggg tcacaccact
    15901 agaatatgca gaccctatca aatggtttaa caatcaagcc aagggaatcg gtgagtatat
    15961 caaggtggac atggtaactg gaaatgcgga tttggtggac ttgaagacac caatcaagta
    16021 ttcagactcg gagtatttta accgtgatgt caaacgtcac ctgcgcttga agtacccgac
    16081 taaaatcttt aaaactccat cttttgaggt ggacgatgag ggcaatcctt tctatgtagc
    16141 aacggtttac caaaagcaat ttggacttgc ggttcctcgt cctgcttcag tcattatctt
    16201 ggatgctaca aatggagaaa ccaaggaata cagcttatca gatgttccag aatgggtgga
    16261 caggatctat ccagcagagg aaaccattga gcaaatcaac tacaacggca agtacaagga
    16321 cggtttcttg aatgccatga tttccaagaa aaacgtgacc cagactacca atggctataa
    16381 ttacttgtct atcggtaatg acatctatct ctacacaggt gtgacgtcgg ctaatgcgga
    16441 tgagagtaat cttggtttca tccttgaaaa tatgcgaaca ggagaaatta ctaagtatag
    16501 cttggcttct gcgacagaag aatcagcccg tgaatcagca gaaggtgctg ttcaggagaa
    16561 atcctacaaa gcaaccttcc caatcctcat caacctcaat gacaagcctc tctacatcat
    16621 gggcttaaag gacaatgctg gcttggtcaa agagtacgcc ctggtagacg cagtcgagta
    16681 ccaaaatgtt atcgttgcta ctacagtgga agagatgctc agcaagtatg ccaataaaaa
    16741 cgaccttgaa attgacaatg caacgacaga aagcatcaag ggagtagtag cagacctcaa
    16801 atcagctgtt atcaagggag acactgtcta cttctttaaa gttgatggca agatatacaa
    16861 ggtaaaggct tcagtatccg atgaccttcc ttaccttgaa aatggtaaaa ccttcgaagg
    16921 tcaagtagga aaagacaact atctcaagac ctttaaagta caataatact cttcaatact
    16981 cttcgaaaat ctcttcaaac tacgtcagct ctatctgcaa cctcaaaaca gtgttttgag
    17041 cagcctgcgg ctagtttcct agtttgctct ttgattttca ttgagtataa aaaaggttta
    17101 tttaagaaat atatgttata ataaggtaaa ttaagcctaa tggaggacaa agaaatgggt
    17161 ttttatttga tggttgcttc aatgctactc ggactgctcg ctttgaagat aggtttttct
    17221 cagttcaagg agaaaaaaga taaattctta tctatcttaa caagtttagc tggcacagcc
    17281 cttgttctcg tggctgtctg gttaggatga cccaaataaa tagaaaaacc tcggtcaaac
    17341 cgaggttttt caaatgaatt tcttggttgt ggctaaaaaa tatgctacac tatcaatatg
    17401 aaaattttaa tcccaacagc aaaagaaatg aacacagact tgccaagtat cgaggcaatt
    17461 cctttaaaac cagaaagtca ggccgtgctt gatgccttgg ctctctattc tgccagtcaa
    17521 ttggagagtt tctacaaggt atcagctgag aaagcggcgg aagaatttca aaatatccaa
    17581 gctttgaaaa ggcaaactgc tcaacactat ccagccttga aactttttga tgggcttatg
    17641 taccgcaaca ttaagagaga taagctgacc gaggcggaac aagattatct tgaaaatcat
    17701 gtcttcatta cctcggcttt gtacggtgtt gttccagcct tgtcacccat ggctcctcac
    17761 cgtttggatt ttttgatgaa attaaaagtc gctggtaaga ctttgaagag ccattggaag
    17821 gcagtctatg atgaagctct gaagaaggaa gaagtgattt tctctctctt gtcatcagag
    17881 tttgagactg tattttctaa ggaaatcaga gcaaagatgg tgaccttcaa attcatggag
    17941 gatagaggcg gtcagctgaa gattcactca actatctcca agaaagcgcg cggggccttt
    18001 ctaacagctt taatagaaaa tcaagtacaa actgtggggg aagcacgtcg cttgaacttt
    18061 gctggatttg tttaccgaga agatttgtca caaccacagg gattagtttt tgtaaaggaa
    18121 gtatagaaat cagataagag aaaagtcagc acgattatgc tgactttttt gataacttat
    18181 aaagtattgg acaaatgaat ctcatttgat aaggtgttaa gatgattaac caaattcatg
    18241 attgacagat gatttcggca aataaacttc ttggtaatcc ctggaatata gaaattagac
    18301 acgatgatat cgtaatctgt ctgatttaaa atctcaggac ttgtttttaa ttcatcccaa
    18361 atatcgaagg taaagcggtt attacagtaa taggaaagca tatcaacaaa ggtaagggat
    18421 atagcatggt caaagttact gataatcaaa accttgatag gtggtcgatt ttctaacaac
    18481 tgagtagaga ggttttcagc atgggttaag atggtgtaca tcaagtgttc caactgttca
    18541 ggatggtcat gctgtccaat tgcctgacgg tattgagcca attcttgacg cgcacttccc
    18601 ataaagtctg ggaagtaaac ttcaaatttt ttaatcgtca atgctttttg ttcaaataag
    18661 attggggtag aaaagatttc ctgtctttca aagaaagcag tgttgtgtaa atgccaaatc
    18721 agctcatcgt ggttagtaaa agtaatctta tattgttttg ataggcgttc taatatttga
    18781 ctaagtaatt ggtaagagta tcttgcttga ctgttatctt ctaaagagtt gaagaattct
    18841 tgaggatcta ggaaaatatc attctgaaga aaagaaataa aaatttgagc gattgtatct
    18901 ggagtcattt caagcccaaa atgtttagag aaataagcaa gtgtctcctg gaaatttgga
    18961 atgctcttta aaagcggata atattctttg taaaagtggt tggggaggtc aatgaagtga
    19021 ccatttttaa ccctgtggat actgatagct atcatcagtt tgtacattct ataaattgaa
    19081 aatcgcattg gataatttgt gattttatag aagaagtcag caaactctgt taaatcttcc
    19141 tcaggaaggt caggaaaagg ccaatctagg aaataatagc gctcagaaaa gtattgggca
    19201 aaaaagtaac gaatatcgat ctcatttcca cgtatctcgg atggagtaaa agataattca
    19261 atttgaaact gagatgaaag aacctttgta atatttctgc ccagtcgata gaggttggca
    19321 ctactaaagt aaagattttc tattgttcga taaataggta gcccctcatt gaagaacata
    19381 tactctagta attgaaaaga ttgagaatta gcaagaaaat attgataaat atcttctaca
    19441 ctagtgttaa cttctaaatc tatcatgatt ccgttaacag aagattggat gttaatagat
    19501 ggaaaggcaa tacgtaattc atttaaatca ctttttaaga ttcgttctgt acatcctaat
    19561 ttttcggcta gttcatgtaa tttcatccaa ttacgattct gaattagggt ttccattaag
    19621 cgtaattgtc tttgaacttt tgtggataaa aggtttctca tacgggtatt tcctccataa
    19681 ttcattatat ctttttttgt ctaagtagta taaaaaaatt agagcaagaa aattgtcgtt
    19741 agtaatcgga aaaattagaa taatataagt ggcttttaag tgcaaaaaca gaatatatta
    19801 attgttcaga aaatattgat taatgcctca aatagttgta cattgtaaac tataaaatac
    19861 tatctaggag tttaaaatga aacattcaca taaaaaatca tttgactggt atagcatgca
    19921 acaacgttat tctattcgta agtattactt tggtgcagct agtgtcttgt tcggtaccgc
    19981 tttggtatta ggtgcagcag ctagtgtcca aacagtacaa gcggaagaaa acaaacaaga
    20041 aactaccaat agtatttctg ttggtagggg agaagcagct actaaaccag cagaggtttc
    20101 tgcgtctaat aaagagaaaa cctatgcagc tccaactgta gctaatccag tagaaacgac
    20161 tccagttaaa actgaagaag ttactaaacc agcagaaaaa gttgaagaag caaaagacaa
    20221 aaaagaggaa gtaacgcatc aagatgccgt tgacaagtca aaattgttaa cggctctttc
    20281 gcgtgctaaa aagttagaaa gcaagttata tacagaagca agtgctgcta acttgcaaac
    20341 aagtatccaa gctggtcaaa gcttgcttgg gaaagcagat gcatctgaag ctgaattatc
    20401 agcagcagag tcatctattc aatcatctat tattggtcta gaacttcgtt ctaactctaa
    20461 caaaggaact gtatcagaaa ctcctgtagc gaagaaagct aatatagttg aagcgaagga
    20521 agagactaat ccagctgcaa caactgatcg ttcagctgtt gatagcgcta ttttgccaac
    20581 tagcacagct gacaaagtag aaacaacttc agctccagca tctattaatg aaatcttgaa
    20641 actaggtttg agcctttctg atgctcgcca aaatccagct atccgtaagg aagatgttaa
    20701 tagagggtat agtggtttta gagcagcacc tgctccaacg aacaaactag taactaatct
    20761 aggaaataat actgttttca ctgatattag cagagggtct catactttcc gtggtaatgg
    20821 gaattcacgt ggtggaaacc cgattcattt tgatgtaaca acaactagag ttggaaatag
    20881 agtagaattc tcaattgcat attctggtcc aggtgagttc gttaataata actttctctt
    20941 agacaaaggg aatggatttg gagaaccatc tcgtgcaact atttcaacaa acagattaag
    21001 agatcaaact aaagatataa gaaagggtgc aaattttgta tctcattcaa gctacagttt
    21061 aacatctgct gttgaaacaa acagtaatca aactattaga tttagtttac ctatagccaa
    21121 ccctaatggt gatctgtctg ttcgattaag acctgttact tttaatgtag gtcaagggga
    21181 atcaggatct gcaactagta atgatccata tagtaactct aactattact tcagagaaaa
    21241 accactcctc ttggatgcaa atccaaatgg tggtactaat aataagactg tttcagaaga
    21301 cattgacttc caaactgtct atcttccaac tagtaagtta ccagaaggtc aaactagatt
    21361 agttcgagaa ggtgaaaaag gacaacgtca aatcatctat aaagttcatc aattgggtaa
    21421 cgaaacaatc ctaggattgc caattagtaa ttcagttatt aaagaagtta agccacgtat
    21481 tatgcaaatt ggtgtggcta aagatctaat cgatacagta aaaccacgtg ttgatcaaaa
    21541 taaagtcggt gatacaaata acctcacttt ctatcttgat aacgatggaa acggtgttta
    21601 tactgagggc gtagacgaac ttgttcaaaa aattgctatt aaagatggtg ctaaaggtga
    21661 aaaaggagtc caaggcgaac gcggcctgac tggagcgcaa ggtcaggcag gtcgtgacgg
    21721 tgtaactcca accgtaaccg ttaaagataa taaaaatgac ggcactcata ctatcactat
    21781 taacgacggt agaggtaatg ttgcaagtac tgttgtaaga gatggtttcg atggcgcaag
    21841 tccattagtt gcgactcaac gaaatgaagc agataagaca acaactgtta tcttctatta
    21901 tgatcaaaat ggaaataatg aattagatgc ttctgataag aaattaaaag aagttattat
    21961 tgcagatggt gccaaaggtg aacaaggtct tcaaggtcgt gatggagctc aaggaccaaa
    22021 aggcgcagat ggacaaagag gaccagcggg accacaagga ccaaaaggag aacaaggtaa
    22081 tccaggaact ccaggtaaag atggaaaatc tctaattgct gttaaaaatg gaactgaaac
    22141 aaaagtctat gtagaggatc cggctagacc aggacaacca cttaatccaa accaaccatt
    22201 agcaactatc actgatggaa gaaatggtac taatggacaa tcaccaacaa ttacagcgac
    22261 acgaagtgtt caaaatggta aaaatggtgt attagtaaca attacaccag taggaggtcg
    22321 tccacaaaca acatttgtag aggatggaca aaaaggtgct gatgggaaaa ccccaacagt
    22381 aacaataact gaggggcaaa acggcacaca tacattaacg gttcataatc caggaagtcc
    22441 agatgtgaca actacgatcc gtgatggagc tacaggacaa gcaggtcgtg atggtaaaga
    22501 tgtattaaac ggaaaagtaa atccacaacc aaaccaaggt aaaaatggag ataaatatat
    22561 taataccgaa accggtgatg tctatgttaa aaacaatgga aactgggata aagaaggcaa
    22621 catcaaaggc cctaaagggg acaaaggtgc agatggtgct aaaggcgaaa aaggagacca
    22681 aggcgaacgc ggcctaactg gagcgcaagg agctaaaggt gcggatggcg cagtaggtcg
    22741 tgatggacgt gacggtaaag acgtgttgaa cggcaaagct aacccagaag cacatcaagg
    22801 taaagacggc gataaatacg ttaatacaga aacaggcgac gtcttcgtta agaataacgg
    22861 caactgggat aaagagggca acatcaaagg ccctaagggt gacaaaggtg aacgcggaga
    22921 agatggtaag actccagaag taactgtaac tccaggtaaa gatggccata gtactgacat
    22981 tacattcact gttccaggta aagatccagt tacagtaaat gttaaggacg gagaaaatgg
    23041 tctgaacggt aaaactccaa aagttgattt acttcgtgtc caaggaaaaa acggaaatcc
    23101 atctcataca attgtgacat tctatacaga tgaaaacaat gacggcaaat atacaccagg
    23161 aactgatgaa cttctaggtt cagaaatgat taaagatggt gctaaaggcg cggacggacg
    23221 agatggtaaa tcattgctta ctgtcaagga tggtaaagaa actaaagttt accaagaaga
    23281 tccagctaac ccaggacaac cattaaatcc agaaaaacca cttgcggtaa ttagagatgg
    23341 agtagatgga aaatcaccta cagttacagc tgttcgtaaa gatgaagcag ggcataaagg
    23401 tgtagaaatc actgttgata accatgatgg ttcacaacca actacagtct ttgttcaaga
    23461 tggtgctaag ggagaaactg gtgcaaccgg tcaggatgga caaactccta caatcactac
    23521 tcaacgtgga caagatggcc aaagcactgt tgtaactatc acaacatcag gtaaagatcc
    23581 agtaaccttc actgtaaaag atggtaagaa tggtaaagat ggccgtgcac cgaaaatcaa
    23641 agtagaagat attacttcac cttcaagaat tagacgcgat acagatgctg ctgcaactcc
    23701 aacgcgtaac ggtatccgtg ttacagttta tgatgatgtt aatgacaatg gggtatacga
    23761 cggaggtgtc gataaagtat taaatagtaa agatatttat aacggtatag atggacgtga
    23821 tggttcagct ccaactatta ctacaaaaga taatggagat ggaacacaca ctatcacagt
    23881 tcaaaatcct gatggttctg aatcaacaac tgttgttaaa gatggtaaag acggtaaaac
    23941 tgcgaatatc actacaacag aaaacccaga tggaagccac acaattacgg tgacaaatcc
    24001 agatggttca actaaagaaa ctgttgttaa aaacggtaaa gacggtaaga ctcctaaagt
    24061 tgaagtaacg gataacaacg atggaacaca cacagttaaa gtgacggatg gagacggcaa
    24121 tgttaccaac gctatcatca aagatggtaa agatggtaaa gctgcaacag caacaactac
    24181 tgaaaatcca gatggaagcc acacagtaac aatcactaac ccagacggaa ctaagaatga
    24241 gtttgttgtt aagaatggac gtgacggtgt tgacggacgt actccaaccg catctgttcg
    24301 tgataatgga gacggaagtc atacaatcgt tattacaaat ccagaaggtg tgacaactga
    24361 aaccacagtt cgtgatggta aatcaccaaa agtgactata actgatgaac aaaatggaac
    24421 tcataagatc tctgttctaa atggtgacgg aacaactact gaaacaatca ttacagatgg
    24481 taaatcacca gtagcaacag ttagagataa ccaagatggt acttacacta ttcgtgtgga
    24541 aaacggtaat ggtactgttt ctgaaaccac agttcgtgat ggtaaatcac caaaagcgaa
    24601 catcgttgat aacggagatg gaactcatac attaacaatc gtagattctg atggtcgtga
    24661 atacaaatct attatcaaag atggtaaaga cggcaaagat agcgtttcac caactgtaac
    24721 tgttaaaaat aataacgatg gaactcacgt tgttacaatc actaatccag atggaagtaa
    24781 gacagaaatg gtgattaaag acggtaaaga tggtaaatca ccaaaagttt ctgttgaaga
    24841 taatggtgat ggtagtcata caatcacaat catcaattct gatggaactg tgacaaaaac
    24901 agttattaaa gatggtagag atggacgtga tggtcgagac ggcaaagacg gtaaagacgg
    24961 taaagatgga aaatgtggat gccaagacaa accagtaaca ccatcaaatg acaaaccagt
    25021 tcctccaaca ccaaatgtgc cgacaccaga agtaccggtt aaacctgtgc cagcgcaacc
    25081 aacaccaaat gtaccgacac cagaagtgcc agtacaacca actccagctg ttccaacacc
    25141 agaagtaccg gttaaaccag taccagcggt tccagaacaa ccagtagtac caacaccggc
    25201 tcaaccagca actccagtaa atgctaaccc agtagcacca actacaggta aagaaaaccg
    25261 tggggacaaa ttacctgaaa ctggaagcca atctgattat atctctgttc ttttaggtag
    25321 cggtattcta ttgagcctat atgtaggacg aagaaaagaa gcttaatcag ccaaaagcag
    25381 tcactaattt ctcgaaagaa gatgataagt gatagatctc gaatgaaaga atattcttag
    25441 aatgattttc ctatgatgga aaagactgct aaaaaccttg agtggtaacg ctcaaggttt
    25501 ttttggatgg ctgatgtttg tctgaaaatc ttgattgaga aataaaaagc caccctatta
    25561 ggtggctata attgatttag actttctaaa attttctatt ttttactgaa tcgcttcgac
    25621 caagtcttga gcttgttttt caagtgagtt taggactgtt tcttcaagaa ccaattttcc
    25681 gtctgcccag gcagagtcat taacacgtgc agcagtgaaa tcaccaacgc cttgtgtacg
    25741 gataaatggc aagaggtctt tgtagatagc gaaaagttga tcgtgccctg cattggctac
    25801 agatgatacg gtgacaaact tgtcttgaag ggcagaaacg ccacgcgtat cagacaagtc
    25861 aagggcacga gatagccagt caagcaagtt ttttactgta ccagggatag agaagttgta
    25921 gactggagag aaaatccaga tagcatccgc aacgagaact gcttcacgag cagcagctac
    25981 agctggatgt gttggaactt ccaaatcttg gctgaagaga ggaagggctg aataatcaag
    26041 gtagctaact tccgctttac cagcaagtgc tttctcagct tcgagcgcca tttggtggtt
    26101 gaaagaacct tgacgtagtg atccgacgat aaataatact tttttagaca tgatgtgtct
    26161 cctttttctt caaattttga gaactctctc gttgttataa aatacattac aacaaaacaa
    26221 aagaacttgc aagaaatttg ctcagagttt atttgaaaat tgtaaaattt cggaaactct
    26281 agtcatttgt gactgaaaaa gtaagaactg tttcactttc aaaatcggtt ttgtttgaag
    26341 ggagaaatag aattggttgc tcaaagcaca gctttgaggt tgcagataaa gctgacgtgg
    26401 tttgaagaga ttttcgaaga gtattcttat attcacttgt aataaagctt aatagatggt
    26461 aaaatagacg agtgaaaaaa agacaaaaca aagcaaaaaa taatctactg tggcagtatg
    26521 gtctagggat gacgattttg tttgtggtta tcagtgcttc ctttctgtat atggtttctc
    26581 ttagcatgaa accctatcaa acagctaaaa gtgaaggaga aaaattagct cagcagtatg
    26641 caggattaga gcaggccgat caggttgatt tatacaatgg cttggaatct tattacagcg
    26701 ttcttggtcg taataaacag caagaagcac ttgctgttct gattggaaaa gatgatcata
    26761 agatttacgt ttatcagcta aatcagggtg tttcacaaga aaaagcagaa acggtttcta
    26821 aggaaaaggg agctggcgaa attgacaaga ttatctttgg tcgttatcaa gataagccaa
    26881 tctgggaagt caagtcagga tctgattttt atctagtaga ttttgaaaca ggagcattgg
    26941 tcaacaagga gggcctatga aattatccaa ccgtgtttta gaaatggaag aaagtgtgac
    27001 tttggctgct ggagcccgtg ccaaagcact gaaggctgag ggtagagata ttttgtctct
    27061 aaccttgggt gagccagatt tcactactcc caaaaatatc caagatgccg ccattgcatc
    27121 gattcgagat gggcgtgctt ctttttatac agtaacctca ggtctgccag agcttaaggc
    27181 ggcggtcaat agctactttg agcgctttta cggctattct gtagcgtcaa atcaagtgac
    27241 agtcgctgcg ggagccaaat attctctcta taccttcttt atggctgtgg tcaatccagg
    27301 tgatgaagtc atcatcccaa ccccatactg ggttagctat ggagatcagg tcaagatggc
    27361 agaaggcgtt cccgtctttg tttctgctaa ggaagacaat cactttaagg tgaccgtaga
    27421 gcagttagaa gcagctcgca ctgacaagac caaggttttg gtgctgaatt cgccatctaa
    27481 tcccacaggt atgatttaca cccgtgagga actcttggca attggaaact gggctgtaga
    27541 aaatgatatt ctcatcctag cagatgatat ctatggccgc ttggtttata atggtcatga
    27601 gttcacaccg atttctagcc tatcggaagc gattcgcaag caaacagtgg tcatcaatgg
    27661 tgtgtctaaa acctatgcca tgactggttg gcggattggt tatgccgttg gagaagcaga
    27721 cattatcgct gccatgtcca agattgcagg tcaaacaact tcgaatccgt cagcagtagc
    27781 ccaatatgca gcagttgagg ctctatcagg tgagcaagat actgtagaaa gcatgcgtca
    27841 ggcctttgaa gaacgtctta ataccatcta tcccctcctt gcagaagtgc caggatttga
    27901 agtggtcaaa ccgcaagggg ccttctatct cttcccaaat gtcaaaaagg ccatggagat
    27961 gaaaggctac acggatgtga cagactttac aactgttatc ttagaagaag ccgaagtggc
    28021 cttggtaaca ggagctggat ttggagcacc agaaaatgtc cgcctcagct atgcgacaga
    28081 cctagacacg cttaaagaag cagtcgaacg cttgaaagca tttatgggta gtgagaatga
    28141 ttgatcattt tgagattaag gtaaaggatt tacaaatttc agaaggattt tataggagtt
    28201 ttctcgctcc tttggactat aaattggctt ttaagactag ttctctaatt agttttctat
    28261 ccccgaacag ccctcatcct ggtggtgatt tttggctgac tcagggaaca caagatcctg
    28321 ttcattttgc ttttttagca gaaaataagg aagaagttca ggcttgttat gaggctggct
    28381 tagaggcagg tgggcgagac aatggggctc ctggttatcg aagtgagcat ccgatttact
    28441 atgctgcttt tatgattgac ctggatggga acaatataga ggtggtttgc cataaagaat
    28501 aaaaaagaaa aggaaaaata atgacaaaac gtgtaacgat tattgacgta aaagactatg
    28561 ttggtcagga agtgacgatt ggcgcttggg ttgccaacaa atcaggaaaa gggaaaatcg
    28621 ctttcttaca attgcgtgat ggaacagcct tctttcaagg tgtggctttt aaaccaaact
    28681 ttgtcgaaaa atttggtgaa gaagtgggac ttgagaagtt tgatgttatc aaacgcttga
    28741 gccaagaaac gtctgtttat gtgacaggta ttgtcaaaga ggacgaacgt tctaaatttg
    28801 gctatgagtt ggacatcaca gacatcgaag tgatcggtga atctcaagac tacccaatca
    28861 caccaaaaga acacggaaca gactttttga tggataaccg tcacttgtgg ctacgctctc
    28921 gtaagcaagt agctgtgttg caaatccgta acgctattat ctatgcaact tatgagttct
    28981 ttgacaagaa cggttttatg aagtttgaca gcccaattct ttcaggaaat gcggcagaag
    29041 attctacaga actctttgaa actgactact tcggaacgcc agcctacttg agccaatcag
    29101 gtcaacttta cctagaagca ggggctatgg ctcttggtcg tgtctttgac tttggtccag
    29161 ttttccgtgc tgaaaaatca aaaacacgcc gtcacttgac tgagttctgg atgatggatg
    29221 ctgagtactc atacttgaca catgatgagt cgcttgactt gcaagaagct tatgtgaaag
    29281 ctcttctaca aggtgttctt gaccgcgcgc ctcaagcctt ggaaaccttg gaacgtgata
    29341 cagaactctt gaaacgctac attgcagagc cattcaaacg tatcacttac gatcaagcca
    29401 ttgacctctt gcaagagcat gaaaatgatg aagatgctga ctacgagcat cttgagcatg
    29461 gtgatgactt tgggtcacca cacgaaactt ggatttcaaa ccactttggt gtgccaacat
    29521 ttgtcatgaa ctatccagca gccatcaagg ccttctacat gaaaccagtt cctggaaatc
    29581 cagagcgcgt gctttgtgca gacttgcttg ctccagaagg ctatggagaa attatcggtg
    29641 ggtctatgcg tgaggaagat tacgatgccc ttgtcgctaa gatggatgaa cttggcatgg
    29701 atcgtacaga atatgaattc taccttgacc ttcgtaaata cggtacagtt ccacacggag
    29761 gatttggtat cggtatcgaa cgtatggtaa ccttcgcagc aggaacaaaa catatccgtg
    29821 aagctattcc attcccacgt atgttgcacc gtatcaaacc ataagaacag gaaaacgccc
    29881 atgtggcgtt ttttcgaatt ctagtgtttt tacttgcgta aaaaaatttt ttctagtata
    29941 atagtttatt gtgagcgaac ctcacttacc ccttgcaaag tcttggggtc attagaccaa
    30001 aaggaggaac atatcaatgg ctaaatacga aattctttat atcattcgtc caaacattga
    30061 agaagaagct aaaaacgctt tggtagcacg ttttgactct attttgactg acaacggtgc
    30121 aactgttgtt gaatcaaaaa cttgggaaaa acgtcgtctt gcatacgaaa tccaagattt
    30181 ccgtgaagga ctttaccaca tcgttaacgt tgaagcaaat gacgatgcag ctcttaaaga
    30241 gtttgaccgt ctttcaaaaa tcaacgctga cattcttcgt cacatgatcg tcaaaattga
    30301 cgcgtaagaa ggtaaactat gattaacaat gttgtacttg tagggcgtat gacacgtgac
    30361 gctgaattgc gttatacccc atcaaatgta gcagttgcga cttttactct tgcagtaaac
    30421 cgtacattta agagtcaaaa tggtgaacgt gaggctgatt ttatcaatgt cgttatgtgg
    30481 cgccaacagg ctgaaaatct tgctaactgg gctaaaaaag gctcacttat cggggtgaca
    30541 ggtcgtatcc agactcgtag ttacgataac cagcaaggac aacgtgtcta cgtgacagag
    30601 gtcgtggctg agaatttcca aatgttggaa agccgtagtg tgcgtgaggg tcacacaggt
    30661 ggagcttact ctgcaccaac tgcaaactat tcagcaccta caaattcagt accagacttt
    30721 tcacgtaatg aaaatccatt tggagcaaca aacccattgg atatttcaga tgatgattta
    30781 ccattctaat ggacaactaa acttataaag gagaaaaaac atggctcaac aacgtcgtgg
    30841 cggattcaaa cgccgtaaaa aagttgatta catcgcagca aacaaaattg aatatgttga
    30901 ttacaaagat actgagcttc ttagccgttt cgtttcagaa cgtgggaaaa tccttcctcg
    30961 tcgtgtaaca ggaacttcag ctaaaaacca acgtaaagta acaacagcta tcaaacgcgc
    31021 tcgcgtaatg gctttgatgc ctttcgtaaa cgaagattaa agaaaagacc cggttgggtc
    31081 tctttttcat gagcttgaaa acaagaaagc gaattaagac cccaacgggt cttttttcac
    31141 aagctttgaa atgagagagc gagttaggct cagtggctcc ctttttacga gtttgaaaac
    31201 aagagaacac attaaaagca cgatggagct ttttcataaa tatgtctttt ttttcatcca
    31261 agaaattaaa ataaaaatga taaacttttt gaaaataggg gatttgccta ctttatgata
    31321 taatggaaag agttagattg aaagaggtag tgagatggac gcgaaattaa gatacaaggc
    31381 aaagaagatc aagattgtct tttttgatat tgatgataca ttgcggaatt caaagacagg
    31441 gtttattcca actacaattc ccactgtttt taaacagttg cgtgaaaaag gaattttaat
    31501 aggaatcgcc tctggacgtg gcatttttgg tgttgttcca gagattcgtg atctcaagcc
    31561 tgactttttt gtaactttga atggagctta tatcgaagat aaaaaaggtc aggtcattta
    31621 tcagcatcag attgaaaagt cagatgttga ggagtatatc tcttgggcta agcaagaagg
    31681 aattgagtat ggcttggttg ggagtcatga tgccaagttg tcgactcgca ccgatatgat
    31741 gagtgaagct atcaatccaa tttatcccga cttagatgta gatcccgatt tccatgaaaa
    31801 agaagatatc tatcagatgt ggacttttga agataaggga gatgacttgc acttgcctga
    31861 cagtctctca gacaaacttc gcatggttcg ttggcatcaa cattcgtctg atattgtgcc
    31921 gatttcaggc tccaaagcga cgggggtgga aaaggttgtg gaacaccttg gcttgaaacc
    31981 agagaaggtc atggtttttg gagatggtct caacgacttg gaactctttg attatgctgg
    32041 aatcagcgtt gccatgggaa tttctcatga taaaatcaaa gaaaaagcag attatattac
    32101 aaaaacatta gaagaagatg gcatttttgc tgccttagaa gtatttggta tggtagaaaa
    32161 agaattgcat tttccacaag tagacattga aacagtagaa ggtcctcttg cgactattaa
    32221 gactaatcac ggagacttac gtatcaagct tttccctgaa catgctccta aaacagtggc
    32281 taactttgta tctctttcaa aagatggcta ctatgatggt gtcattttcc accgtattat
    32341 caaggacttt atgatccaag gtggagaccc aactggaact ggtatgggtg gccagtcaat
    32401 ctacggcgaa tcttttgagg atgaattctc agaagagctt tacaatatcc gtggtgctct
    32461 ttctatggca aatgctggtc caaataccaa cggcagccag ttctttatcg tgcaaaacca
    32521 acacctacct tattctaaga aagaaattac tcgtggtggt tggccagaac cgattgcaga
    32581 aatctatgcc aatcaaggtg ggacacctca cctagaccgc cgtcacacga tttttggtca
    32641 gttagctgat gaagcatctt acgctgtctt ggatgccatt gctgctgttg agacaggagc
    32701 tatggacaag ccagttgaag atgttgtaat tgaaactatt gaaatcgagg actaagatga
    32761 aaatcggtga taagctaaag gggcgtatta cagggattca gccctacggt gcctttgttg
    32821 agttagagac gggtgatacg gggctgattc acatttcaga gattcggaca ggatttattg
    32881 aaaatattca tgaaaccttg aaagtcgatg aagaggttca agttcaggta gtggatttag
    32941 atgaatttac agggaaagcc agtctctcta tccgcacttt ggaggaagaa aagtaccagt
    33001 ttcctagacg gagacgcttt tcaagcgacc gctttaacta cggttttgct ccctttcgac
    33061 gaatgctacc aatctggact ggagaagctc tgcaccattt aaaaaagaag aagtagttta
    33121 gagttttata ttttttgtaa tgttaatata aatttattat aataggacca tggaagaaga
    33181 acaattatta aaatcaggag agcgcattaa ccagctcttt tcgacagata tcaaaatcat
    33241 tcaaaataga gaggttttta gttattcggt ggatagtgtt ctcttatcac gatttccacg
    33301 ttttcctaag aaggggttga ttgtggattt ttgtgctggg aatggagcag tggggctttt
    33361 tgctagcact cgtactcaag cacagatatt gtctgttgag attcaggagc gtttggcgga
    33421 tatggctgaa cgctctgtcc gtttgaatgg attagaggaa caaatgcagg tcatctgcga
    33481 tgatttgaaa aatatgcctg ctcacattca ggggagtaag gtggatatga ttttgtgtaa
    33541 tccaccctat ttcaaggtgg atcctcattc taatctgaac gagagtgaac attatctctt
    33601 ggctcgacac gaaatcacga ctaatttgga agaaatctgt catagtgccc agagtattct
    33661 caagtctaat gggcgtttgg ccatggttca tcgtcctgat cgacttctgg atattttgga
    33721 tacgttaaaa cgacataatc tagcccctaa gcgcctgcag tttgtttatc caaaaagaga
    33781 aaaggaagcc aatatgcttt tgattgaggc gatcaaggat ggctcaacaa gtggctttaa
    33841 ggtcttacct cctttgattg tccacaatga tgatggctct tatacgcccg aaatcgaaga
    33901 gatttattat ggatcataag gcttatatgt acgttctgga gtgtcgtgat ggatcctact
    33961 atataggcta tacgactgat atgagaagac gcctcgctat ccacaatagt gggaagggag
    34021 ccaaatatac acgagcacgc ttgccagtca aacttatcta tgctcaaggt tttgccagta
    34081 aggaagaagc catgtcggct gaagctcttc tcaagcgtaa gaagaggcca cagaaggaag
    34141 aatttttatc tgaaaatcaa gatagaaatt tactcagtta ttttgaagaa tcgtggggag
    34201 tcctttgact cctcttacct ttgtcaaaaa gcgaaaaaaa tgctacaata aagaaaataa
    34261 acaaaatgag gtattatcat gtccaagatt ctagtatttg gtcaccaaaa tccagactca
    34321 gatgccatcg gatcatctgt agcttttgcc taccttgcaa aagaagctta cggtttggat
    34381 acggaagctg ttgcccttgg aactccaaat gaagaaacag cctttgtctt gaactatttt
    34441 ggtgtggaag caccacgtgt tatcacttct gccaaagcag agggggcaga gcaagttatc
    34501 ttgactgacc acaatgaatt ccaacaatct gtatcagata tcgctgaagt agaagtttac
    34561 ggtgttgtag accaccaccg tgtggctaac tttgaaactg caagcccact ttacatgcgt
    34621 ttggagccag ttggatcagc gtcttcaatc gtttaccgta tgttcaaaga acatggtgta
    34681 gctgtgccta aagagattgc aggtttgatg ctttcaggtt tgatttcaga tacccttctt
    34741 ttgaaatcac caacaacaca cccaacagat aaaatcattg ctcctgaatt ggctgaattg
    34801 gctggtgtga acttggaaga atatggtttg gcaatgttga aagctggtac caacttggct
    34861 agcaaatctg ctgaagaatt gattgacatc gatgctaaga cttttgaact caacggaaat
    34921 aatgtccgtg ttgcccaagt gaacacagtt gacatcgctg aagttttgga acgccaagca
    34981 gaaattgaag ctgcaatgca agctgccaac gaatcaaacg gctactctga ctttgtcttg
    35041 atgattacag atatcgtcaa ctcaaactca gaaatcttgg ctcttggtgc caatatggac
    35101 aaggtcgaag cggctttcaa cttcaaactt gaaaacaatc atgccttcct tgctggtgcc
    35161 gtttcacgta agaaacaagt ggtacctcaa ttaactgaaa gctttaatgc gtaagatttt
    35221 gggtgtcagc tcaaaatcgg aaagtctagt ttgccttata tcgaaaggag tttcggctcc
    35281 tttttttcta ggagtgaagt atgttagaaa atggcgattt gatttttgtg agagatgggt
    35341 cagacatggg acaggccatc cagacttcca caggtaacta tagccatgtt gccatttatt
    35401 tggatgggat gatttatcat gctagtggac aggctggtgt tgtctgtcaa gaaccggcag
    35461 acttctttga gtccaatcat ttatacgacc tctatgttta cccagaaatg gatatccagt
    35521 cggtgaagga aagagcttgc agacatcttg gagcacccta caatgcttct ttctatccag
    35581 atgcagctgc tttctactgc tcccagtata tagcagaaat cctacctatt tttgaaacta
    35641 ttcctatgaa atttggagat ggggaacagg agattagtga tttttggagg gagtattaca
    35701 tagaactagg tctgcctgtt cctctgaacc aagctgggac caatcctagt cagttggcag
    35761 catcgcctct gttacaatgt aaagaaaggg atcttcatga ttcagatttt taatccatct
    35821 cgtttgacga gacagccatt tttggagaat tgatccgcta tctggaccag tatgaggatg
    35881 tgattctacg ggaaattaag gctcagtttc cagatgttgc agttgataaa ctcatggaag
    35941 agtatataaa ggcaagcttg attctacgtg aaaataagcg ctattacctt aattttccta
    36001 cgcttgaatc acttgatagt cttgaactgg atcaagagat ttttgtcaga gaagctagtc
    36061 cggtctatca agccttgttg gagcagagtt ttgagacgga attgcgcaat caaatcaatg
    36121 cagctatttt agttgaaaag acggactttg cgcgcattaa aatgaccctg tccaattatt
    36181 tttacaaggt caaacagcag tatcctttga cagaaaaaca gcaggagctc tatgacattt
    36241 taggagatgt taatcctgag tatgcactca agtatatgac ggcttttttg ttgaaatttc
    36301 tcaaaaaaga ccagcttatg cagaaatgcc gtgatatctt tgtggacagt taggttgtct
    36361 taggctatat tgtgcaaaat gaagatggaa agtatgagtt ggctatcgat tttgataagg
    36421 agaggttaac tttctactta gcgtgatttc ttgtttctga gtacattgtt tgactttcct
    36481 tagtattcgg tataaactat atgtaaccgg taacacatat cggaataaac taaaggagac
    36541 aatcatatgt cacttgaaaa caaattggaa caagcaacag gcgctgtcaa agaaggtttt
    36601 ggtaaagtta ctggagacag caagacagaa cttgaaggag ctgttgaaaa aacagtttct
    36661 aaggcaaaag acgttgtaga agacgcaaaa ggtgctgtag aaggtgccgt tgaaggtttg
    36721 aaaaacgttt ttactaaata ataggaaaaa atcaagggtt tcattttccc ttgatttttt
    36781 ctattcttat aaataatttt ctgcgacggc tgtatctcct gggtaggatt ctttcttgcc
    36841 ctggatgatt tggtaacaat cggctccctt acccgcaata ataactgcat ctaattcgtg
    36901 atttgtgata gccattgccg ccttgatggc ttcttggcga tccgcaatct tctcaacagg
    36961 atgattgatg tagctactaa tttcatctgc aatggccatt gggtcttcat agttagggtc
    37021 atcagcagtc agaaagactt gaatctcagg gtgttgattg aggaggaggc caaagtcctt
    37081 acgacgactt tctcccttgt ttcctgttga tcccagaacc agagcaatct ttctggtttg
    37141 atgagtttca accacattga tgagtttttt cagactatcc ccattgtggg catagtcgat
    37201 gaagaccttg gctccatttt tctgagtgag gacttccata cgaccaggaa cgcgggttgc
    37261 agcgatgcct tttttgatgt cctcaagact tgctccgaga cggagacaag caagtccagc
    37321 agcaactgca ttttcttggt tgaagttgcc aatgagttgg atatcataat ctccagcgag
    37381 tttacccgta gctgaaaatc taaaggcttt ggaattctcg atttggttat caaattggct
    37441 accatagaaa tcatggtctt gatcttcaac ctgttctttc aagactgaga agtggtccat
    37501 gtcactgtta atgatgactg ctcggctatt ttccatcaag agacgcttgt ggtagaaata
    37561 gtcttcaaag ctagggtgtt caatcgggcc gatatggtct aggctgatat ttaggaaaac
    37621 tcccacatca aaggttagac catagacacg tttgaccaga taggcttgac tggagacttc
    37681 catgatgagg tgggtacggt cattttgcac agcctgattc atcatgtcaa agaggtcaat
    37741 actctcaggg gttgtcaacg ctgacttaaa gaaagtctct ccatcaagag ttgtgttcat
    37801 ggtcgacaac atagcaggtc gatgcccttg agataagatg ttataggcga aataggctgc
    37861 tgttgtctta cccttagtac cagtaaaggc aaggagtttg agtttttcct gtggattacc
    37921 atagaactcc atggcaatca aactcatggc tttctttata tcgttcacaa tgatgacagg
    37981 gataccgact tcgtagtcct tttcagctat ataccaagct aagccttgtg ttatagcaga
    38041 aagaaggtat tcttttttaa aggcagcgcc ttttgcaaaa aaaagagtgt cttctgttac
    38101 ttttcggctg tcgtagctga tgctatcaaa aacaactttg ctgtagttgt agtggtaatg
    38161 accttggtca ataatttcgc gaaaaaggcc atctttcttt aaaatatcta atacagtttc
    38221 aatttttatc atactttcta ttgtaaaccg aaagtcgcaa atttacaagt aacaaggaaa
    38281 agtttataat ggaagataag gagtttttcc tagttatcaa aattgaatga ggaatctatg
    38341 tcgcacgaaa acaatcacca gcaggcccag atgttacggg ggactgcttg gctaacggct
    38401 agtaacttta tcagtcgcct actcggggct gtttacatta tcccttggta catctggatg
    38461 ggggcttatg cagctaaggc aaatggtctc tttaccatgg gttacaatat ctatgcttgg
    38521 ttcttgttgg tttcaacagc ggggattcca gttgcggtgg ccaagcaagt tgccaagtat
    38581 aataccatgc gagaagaaga gcatagcttt gccctgattc ggagcttctt aggctttatg
    38641 acaggactag gcctggtttt tgctttagtc ttgtatgtct ttgctccttg gctagcagac
    38701 ttgtctggcg tgggcaaaga cttgatccca atcatgcaaa gcttggcttg gggagtcttg
    38761 attttcccgt ctatgagtgt tatccgagga tttttccaag ggatgaataa cctcaaaccc
    38821 tatgccatga gccaaattgc tgagcaggtc attcgtgtta tctggatgct cctagcaacc
    38881 tttatcatta tgaagctcgg ttcaggagat tatctagcag ccgttaccca atcaaccttt
    38941 gctgcctttg tcggtatggt agccagtttt gcagtcttga tttatttcct tgcccaagaa
    39001 ggttcactca aaagagtctt tgaaacagga gataagatta acagtaagcg tctcttggtt
    39061 gataccatta aggaagccat tccttttatc ctgacagggt ctgccatcca gctcttccag
    39121 attttggatc agctgacctt tatcaatagt atgagctggt ttaccaacta cagcaatgag
    39181 gacttggttg tcatgttttc ttatttctca gccaatccta ataaaatcac gatgattttg
    39241 atttctgtag gggtttcgat tgggagtgtt ggtttgccac ttttgacgga aaactatgtc
    39301 aagggggact tgaaagcagc ttctcgtctc gttcaggaca gtctcaccct actctttatg
    39361 ttcttgctac cagcaacggt tggagtggtt atggtaggag aacctcttta tacggtcttc
    39421 tatggtaagc cagatagttt ggctctgggc ttatttgtct ttgcagtttt gcagtctatt
    39481 attttaggct tgtacatggt cttgtctcca atgcttcagg ccatgttccg caaccgcaag
    39541 gccgttctct attttatcta tggttctatt gccaagctag tcttgcaact acctaccatc
    39601 gccctcttcc acagttatgg tcctttgatt tcaacaacca ttgctctcat cattcctaac
    39661 gtcttgatgt atcgggatat ttgtaaagta actggtgtca agcgcaaggt gattttgaag
    39721 cgaaccattt taatcagttt gctgacccta gtcatgtttc tgttaatagg aaccatccag
    39781 tggctgttag gatttttctt ccaaccaagt ggacgtttgt ggagcttctt ttatgtagct
    39841 cttgtcggtg ccatgggggg tggactttat atggttatga gtctgcgtac ctatttgtta
    39901 gataaggtaa taggaaaagc ccaagcagat cgcctgcgag caaaatttaa gctttcgtaa
    39961 ggtagcattt ataaataaaa ggaataagtt gaacaatctt ttaggagaac ttgaaactta
    40021 ttcctttttt agcgtaaaaa tagctaaaat tatctttcaa aaatagaaaa tgaggttttt
    40081 ttgatttttt ggaaaaaaca attgactaaa caaaccaaga gttgtataat aaaacaaata
    40141 tttaaagcag gaggttccgg aaatgaaaaa gtctaagagc aaatatctaa ccttggcagg
    40201 tcttgtcctg ggtacaggag ttttattgag cgcgtgtgga aattctagca cggcgtcaaa
    40261 aacctacaac tatgtttatt caagtgatcc atctagcttg aactatctag cagaaaaccg
    40321 cgcaacaacc aatgatattg tgaccaatct ggtagatggt ctcatggaaa atgaccaata
    40381 tgggaactat gtgccatcct tggcagaaga ttggactgtt tctcaggatg gtttgaccta
    40441 tacctacaaa cttcgtaagg atgccaagtg gtttacttct gagggagaag aatatgcacc
    40501 tgtaactgcc caggattttg tgacaggatt gcaatatgca gctgataaaa aatcagaagc
    40561 cttgtatcta gtgcaggact ctgttgcagg tttggatgac tatatcactg gtaaaacaag
    40621 cgacttttca actgtcggta tcaaggctct tgatgatcaa accgttcaat acaccttggc
    40681 tcgaccagaa ccttactgga actcaaaaac aacctcaacc attcttttcc cagtcaatgc
    40741 agatttcttg aaatcaaaag gggatgattt tggcaaggta gaccctgcta atattttgta
    40801 cagtggacct ttcttgatga aagcttttgt ttcaaaatct gtcatcgaat acaagaaaaa
    40861 tcctaactac tgggatgcta aaaatgtctt tgtagacgat gtgaaattga cctactatga
    40921 tggtagtgac caagatgctc ttgttcgtaa ctttacagac ggagcctata gctatgcccg
    40981 tctctatccg aatagttcaa gttttgaagg gattaaagaa aaatacaaag atgatatcat
    41041 ctacagtatg caggatgcta cgtcttatta ctggaatttt aacctagata gacaagctta
    41101 taaatttact tctaagacga ccgacattga aaagaaatca actcaggaag cagttcttaa
    41161 taaaaacttc cgtcaagcca ttaactttgc ctatgatcgt acctcctatg gggctcaaac
    41221 tcagggagaa gacggagcga ctaagatttt gcgtaacttg gttgttcctc caacctttgt
    41281 aagtatcaaa ggaaaagatt ttggtgaagt agtagcctct aagatggtca ataattatgg
    41341 taaggaatgg caaggcatca actttgcgga tggtcaagac ccttactaca atcctgagaa
    41401 agccaaggct aaatttgcgg aagctaagaa agagctagaa gctaagggag ttcaattccc
    41461 tattcatttg gatgcgacag ttgaccaagc ttctaagaag gggattcaag aagtaagctc
    41521 tatgaagcaa tctattgaag cagctttagg tacggagaac gtcgttattg atatccaaca
    41581 gttatcaaca gaggactatg ataactcaag ttaccttgct cagactgcta ttcagaaaga
    41641 ctacgacctt tacaatggtg gttggagtcc tgactactta gatccatcaa cctatcttga
    41701 tatctttagt gtcaagaatg gtggggttct acaaaatctt ggactcgacc ctggtgaagc
    41761 caatgacaag gctaaggcag ttggacttga cacttatact caaatgttgg aagaggctaa
    41821 taaggagcaa gacccagcca aacgttatga gaaatatgct gatattcaag catggttgat
    41881 agatagttct ctagcgattc caaatgtttc attaggtgga acgcctagct tgagaaaaac
    41941 agttcctttc tcagcacctt attcattggc tggtaataaa ggggttgaat catataaata
    42001 cctcaaagta caagataaga ttgtcacaac agacgaatat gcaaaagcca gagaaaaatg
    42061 gttgaaagaa aaagaagaat ccaataaaaa agcccaagaa gaattggcaa aacatgtcaa
    42121 ataaaatcta attgtagata agtttgtgta agaagtcttt gtgcttaaaa acgcataata
    42181 tcaggtatat aaaatcctag atgttatgcg ttttgttata ggaagattta ttagatttta
    42241 tcctcaaatt gagttattct cgactttatc cgttgaaata ttataaggag tatttatgaa
    42301 attaaaatta ttaagagtag atactaaggt gattatgggg agtttcttac ttgttctgtc
    42361 tagtctactt gctttgttgc ttccccttat cttaaagggt ttaatagatg ggagttctat
    42421 tgaaaatata ggttccaaag tatttcaatc gtttttgatt tttattggtc aagccttgtt
    42481 ttcttctatt ggttactatc tgtttagtca atcgggtgaa aaaaagatag caaaaatcag
    42541 gaaaaaagtg atagaggggt tgatttatgc agagaaatcc ttctttgata agagccaaag
    42601 tggggagttg acttctgcca ttgtcaatga catgagtgtc attcgtgagt ttttaattac
    42661 gactttccca aatattattc tgagtttagt tatggtactt ggttccattg tagtcttatt
    42721 tagtcttgat tggaatcttt ctctactttt attcatcact cttccttgta tgatgtttat
    42781 tatcttgccc ctttccaata tcagtgaaaa gtatagtcgt cgtttacaga aggaaatcgg
    42841 atttttaaca gggcaattga ctgaaaagat tcaagaacat gaattaatta agactaacca
    42901 agcagagaaa agtgtacaga atgttttgga taattgtatt gaaagggtac aaaacaattc
    42961 actgaaatca gatagggtta cttcttttga gaccccgttt gctctcttat ttatctttgc
    43021 gactatagct gtgatgctaa cctatgggag ttatcgggtc agcgcaggat atatatctgt
    43081 gggaaccttg gtttcgtttt tgatttacct ctttcaatta cttaatccta ttagtaatat
    43141 agctaatttt gtaactgttt attctaggag caagggatct taagttgcac tggagaactt
    43201 gcttgcagtt cctaaagaaa aatttgagtg aggaaaatcg gtatcaggac aagggttgaa
    43261 ttttaaccat gtctattttg gttatgatga aaatcgacct gtcttaaagg atattacttg
    43321 ttcaattttc aaggggcaaa aaattgcttt tgttggacca tctggatcag gaaaatcaac
    43381 gattgtgcgt ttgttagagc ggttttataa accgctttca ggagatattc taatggagca
    43441 atcaagtata tatgatttta acttaaaaga gtggagaagt aaaatcgctt gggtttcaca
    43501 aaataatgca gtcttatctg gcagtattcg tgacaatctt tgtctcggtt tgaatcgctt
    43561 agtaactgat gatgaattga tgaaagtgct agacttagta tcactaggtg atgagattcg
    43621 ctccatgaaa gagggactag atactgaagt tggtgaacgc ggacgattct tgtcaggggg
    43681 gcaaagccaa agacttcaaa tagctagaac ctacttaaaa gatgctgaaa ttcttatatt
    43741 tgatgaagcc actgctaatc ttgatgcgga ttctgagtat gcgattatca gtagcctcta
    43801 ttctgtatta aaggagaaga cggttgtgat tatagcgcat cgtttgtcaa cggtaaaaga
    43861 tgtggattgt attttcttct tagaggaggg gaaaatcact ggctcaggaa ctcataagga
    43921 actactggaa aatcatgagc gttatgctcg ttttgtgcag gagcaaatga tagagtgaag
    43981 tgtcttttga gattcaccat tttatagtct attaaaggga gcaggaaaaa ctcccttttt
    44041 atatagtttg aaactataac tagctcttga aaagaagaaa atgagttgat gaaaataagt
    44101 ggtacaatag ttactataga tttggaggta ttgtatgagc aaggaattac acattaacac
    44161 aattttggcc caggcgggta ttaagtcaga tgaagcgaca ggtgcattgg tgacaccgct
    44221 tcatttttca acgacctatc agcatccaga gtttggtcga tctactgggt ttgactatac
    44281 gcgcactaaa aatccaactc gtagtaaggc tgaggaagtc ttggcggcta ttgagtcagc
    44341 agactatgcc ttagcgacta gctcagggat gtcagctatt gtactggcct ttagcgtctt
    44401 tccagtagga agtaaggtct tggcagtgcg tgatctttac ggtggttctt ttcgctggtt
    44461 taaccaagtg gagcaggaag gtcatttcca ttttacctat gccaatacag aagaagagtt
    44521 gattgccgag ttagaaaagg atgtggatgt tctctatatc gaaaccccaa ccaatccctt
    44581 gatgttggaa tttgatatcg aaaaactagc aaaattggct catgctaagg gtgccaaagt
    44641 ggtggtggac aataccttct atagccctat ctaccaacgt ccgattgaag atggagcaga
    44701 tatcgttctc cattcagcaa ccaagtatct agcaggccac aatgatgtct tggctggagt
    44761 ggttgtgacc aatagtttag aactatacga gaagcttttt tacaatctta atacaacagg
    44821 ggcagtcttg tctccatttg acagctacca gttgcttcgt ggtctcaaga ccttgtctct
    44881 tcgtatggag cgctcaacag ctaacgccca agaagtggtt gcctttttga aggattctcc
    44941 agcagttaag gaagttctct acactggtcg tggaggcatg atttccttta aagtagccga
    45001 tgaaacacgc attcctcata ttttgaacag tctcaaggtc ttctcttttg cggaaagttt
    45061 gggtggagtg gaaagtctta ttacttatcc aacgactcaa actcatgctg atattccagc
    45121 agaggtacgc cattcttatg gtttgacaga tgacctcttg cgtttgtcta ttgggattga
    45181 ggatgctaga gatttgattg cagatttgcg ccaagccata gaaggataag acaaagatgg
    45241 gaaaatatga ttttacaagc ctgcccaacc gtttagggca ccatacctat aaatggaaag
    45301 aaacagaaac ggatagtgaa gttctaccag cttggatagc ggatatggac tttgtggtct
    45361 tgcctgaaat ccgccaagcc gtgcaaactt acgcagacca actggtttat ggttatacct
    45421 atgccagtga agacttaatt aaggaaattc aaaagtggga agctacacaa tacggttaca
    45481 actttgacaa agaggctctt gtctttatcg agggtgtggt accagccatc tcaacagcta
    45541 ttcaaacctt tacaaaagaa ggcgaggcgg ttttaattaa cacgcctgtc tacccaccct
    45601 ttgctcgcag tgtcaagttg aataatcgta gattgattac taattcctta gtggaaaagg
    45661 atggtctgtt tgagattgac tttgaccaac ttgaaaagga tttggtggaa gaggaggtta
    45721 aactctatat tctttgcaac cctcacaatc ctggtggacg tgtttgggaa aaagaagtgt
    45781 tggagaagat tggccaactc tgccaaaaac acggtgtttt gttagtttcg gatgagattc
    45841 accaagattt gaccctcttt ggtcacaaac accagtcttt caataccatc aatcctgcct
    45901 tcaaaaattt tgctatcgtc ttgagcagtg ccactaaaac atttaatatt gctggaacaa
    45961 aaaattccta tgcagtcatt gaaaatccta agttgagact ggctttccag aaacgcctgt
    46021 tggccaataa tcagcatgaa atttcaggct tgggttattt ggcgacagaa gctgcctatc
    46081 gatacggtaa agattggcta gaggaactca agcaagtctt tgaagaccac atcaattatg
    46141 tggtagatct atttggaaaa gagactaaaa tcaaggtcat gaaaccgcaa ggtacctact
    46201 tgatttggct tgacttttca gcctatgacc tgactgatga aacattgcaa gagttgttga
    46261 gaaatgaagc caaggttatc ctcaaccgtg gtttggattt tggagaggaa ggaagtctcc
    46321 atgcccgcat caatatagct atgcccaaat ctctgttgca agaagtctgt cagcggattg
    46381 tggctacttt tgccaaatgt taaaaatcca gccttctagg agaaaagtct tcctagaagg
    46441 ctattttcat aggcgaaaat atggtataat aaaaagataa ggtaaaggtg aaaatatggc
    46501 taaattgatt ccggggaaaa ttcgtatcga aggtgttgcc ctttatgaaa ctggtaaggt
    46561 tgatatcatc aaggaaaaga acaatcggct ctacgctcgc gttgcagaag aagaactgcg
    46621 ctatagttta gaggatgatt tggttttttg tgcctgtgat ttttttcaaa agaggggcta
    46681 ctgtgtgcat ttggcagcgc tagagcattt tctgaaaaat gatgagcgtg gtcaggaaat
    46741 cttgtggagt ctggaagaag gtcatgaaga aaaagaggcc gttgaaacca aggtgacctt
    46801 gggtggcaag tttttggatc gaattttatc tccaaaatca gaatgcgcct atgagttatc
    46861 agctgtgggt caggtggaag caggaaccaa tcatatcttg tggactctga gaatcggcca
    46921 aatcaatagc caaaaatact atatcattcg ggatattcca ctttttttaa ggattgtcga
    46981 gcagagaaag tcgtatatga ttggcaagat ttatgaggag tctctttctt gggaagcctt
    47041 tgatgatgcc agccaagaac ttttgacttt cttgcacgga ctaacggagg aagggctggt
    47101 tccagacctc tttttccaaa accaaggtcg gcacctcttt ttccctctga ccttttttga
    47161 gcagggtgtg aatttactga tggccttgcc ccattttcaa tttgaccatc aagtggatag
    47221 ctaccaaacc ctgctttttc aggatatgca tgctgatgcc aatctatttg cctttgcagt
    47281 aacagaatac tcggattatt ttgaaatgga aatcagtgag agtcctaggg tcaatgtctt
    47341 ttatcaggga gcagtacttt tccataaagg tcaggtttat tttttaacag accagcagat
    47401 gcgtcttctc aaggaaatta aagcgttacc tgtgggtcaa caaggaaaga aatacctgca
    47461 atttgatagc agtgatcgag acaaattggc ctcctgtctg actcttttta tccagatggg
    47521 caccgtttca gctccagaac gtctacaaat caaaactttt gcgccctctt tttactttga
    47581 cagggaagaa gataatcgga ttcgtttaga aattcagttt gattatggaa atagacaggt
    47641 atctagccga caagagctag aagaattacc cttttcaagt gacgcagact tagaagaaag
    47701 aattttccaa gtctgtttgg ctgcgggctt tgaagccgat tttcaatctt ggcgtcaggc
    47761 cttaaaagcg gagtctgtct atcatttttt tcatgatatc attccagtct ttgaaaaact
    47821 cgggcatgtt gacctatcag ataaactaga agagctttat agcctagcga gtcctcaggt
    47881 gcagattgcc tccaagggag gtctcttgga aatccagttt gattttcaaa atattgccca
    47941 ggaggaaatc gaccaagcca tgcaggcctt ggttgccaat caggattttt atattgattc
    48001 gtctaatcaa gtttactttt tcgatgaaga aaccaggaaa attcgccaaa atctacagga
    48061 actggggcaa tttgaattaa aagatgggac cttgcaggct cggaaatcct tggcctacag
    48121 tttagctcat ctctttgaag ggcgagaccg tgtttctttt tcacaagaat tccagaatct
    48181 ggcccaggat ttgacgcatc cagaggactt tcctttgcaa gcaactcagg tcaaggctga
    48241 cttgcgagat tatcaggaaa agggaattgg ctggttgcag atgctccatc attatggttt
    48301 tggtgggatt ttggctgatg atatgggact tgggaaaacc cttcagacca ttgctttttt
    48361 gactagtcaa gtgacaaaag aaagtcgggt tttgattctc gctccgtcgg gtttgattta
    48421 caactgggca gatgagtttc agaaatttgc tccacagttg gatgtggctg ttgttcatgg
    48481 tttgaaagca agtcgtgagg agattcttgc cgagagccat caaatctatg tgactagcta
    48541 tgccaccttc cgtcaggaca gtgagtttta tcaggggatg gcctttgact tccttttctt
    48601 agatgaggct caggtcatga aaaatgccca gaccaagatt gcccagacct tgagacaatt
    48661 tgtggtgccg tcggtctttg ccttgtcagg aactccgatt gaaaaccatc tgggtgagtt
    48721 gtggtctatt ttccaaatcg tcatgcccgg acttttgcca agcaagaaag aatttatgaa
    48781 attgccagca gagcgagtgg ctcagtttat caagcctttc gtgatgcgac gcaagaaaga
    48841 agaagttctg actgaattgc cagacttgat tgaggtggtt tataaaaatg aactggaaga
    48901 ccagcaaaag gctatttacc ttgcccagtt acaacagatg cgagaccatc tggctcaagt
    48961 gtcagaacag gaatttcagc gaagtcgtgt ggaaatttta tctggtttga tgcgcttgcg
    49021 tcaaatatgt gacactcctg ccctgtttat ggaagattat cagggagcca gcggcaaact
    49081 agatagtctc cgagacctac tggtacaggt ggcagacggc ggacaccgtg tcttgatttt
    49141 ctctcagttc aagggaatgt tggaaaaaat tgaacaagaa ctgccagact tgggcctgac
    49201 atcctttaaa attacgggtt caaccccagc caaggaaaga caagacatga ccaaggcctt
    49261 taaccaagga gaaagagatg cctttctgat ttccctcaag gctggtgggg tcggtctgaa
    49321 cctgacaggt gcagatacag tgatcttggt tgacctttgg tggaatcctg cggtggaagc
    49381 gcaagccatt ggccgtgccc atcggatggg tcaggaagaa acggttgagg tctatcgctt
    49441 ggtgaccaag ggaaccattg aagaaaaaat tcaggaactc caagaacaaa agaaacatct
    49501 ggtgtcacaa gtattggatg gcacagagtc acgtggtagt ctgaccctag cagaaattag
    49561 agaaattttg ggaatttctg aagccagcac ttgaaaaatc aagacaatac gctataatga
    49621 agtgttgaaa ggaaatagaa aatgaaacaa gaacgatttc cattggtgtc agatgacgag
    49681 gtcatgttga ctgaaatgcc agtcatgaat ctctatgatg agtctgatct gatcagtaat
    49741 atcaagggtg agtatcgaga taaaaattat ttagaatggg ctcctattac tgaagaaaaa
    49801 ccagtaaaac cgattgaaaa gcaagtcgaa aaacctaaaa aggctccttt aggggttaaa
    49861 aaagaaggaa agagctatgc ggaggtggcg cgtgaagaag cgcgtgcgga cttgaaaaag
    49921 aaacgctctg ctaactacct aactcaggat ttcagccttg cgagacgtca ttctcagccc
    49981 agtctagtta gacagggcaa tcaaccgaca actcctttcc aaaaggaaaa tcctggtgaa
    50041 tttgtcaaat atagccaaaa attgacccag tctcattata tcttggcgga agaagttcat
    50101 tctatcccta ccaagaatga agaagtgtca gcacctgctc caaagaaaaa caattatgat
    50161 tttctaaaga agagccaaat ctacaataaa aaaagtaaac aaacagaaca agaacgtcgg
    50221 gttgcccaag agttgaatct gaccagaatg acagaatagg ggagaaaaca tgtcaaagac
    50281 atatcatttt atcggaatta agggatcagg gatgagtgcc ttggccttga tgttgcacca
    50341 gatggggcac aaggttcagg gatcagatgt tgaaaagtac tactttaccc aacgcggtct
    50401 tgagcaggca ggaattacca ttcttccttt tgatgaaaag aatctagacg gtgatatgga
    50461 aattatcgct ggaaatgcct ttcgtccaga taacaacgtc gaaattgcct atgcggacca
    50521 aaatggtatc agctacaaac gttaccatga gtttctaggt agctttatgc gtgactttgt
    50581 tagcatggga gtagcaggag cacatggaaa aacttcaacg acaggtatgt tgtctcatgt
    50641 cttgtctcac attacagata ccagcttctt gattggagat gggacaggtc gtggttcggc
    50701 taatgccaaa tattttgtct ttgaatctga cgaatatgag cgtcacttca tgccttacca
    50761 cccagaatac tctattatca ccaacattga ctttgaccat ccagattatt tcacaagtct
    50821 cgaggatgtt ttcaatgcct ttaacgacta tgccaaacaa attaccaagg gtctttttgt
    50881 ctatggtgaa gatgctgaat tgcgtaagat tacgtctgat gcaccaattt attattatgg
    50941 ttttgaagct gaaggcaatg actttgtagc tagtgatctt cttcgttcaa caactggttc
    51001 aaccttcacc gttcatttcc gtggacaaaa cttggggcaa ttccacattc caacctttgg
    51061 tcgtcacaat atcatgaatg cgacagccgt tattggtctt ctttacacag caggatttga
    51121 tttgaacttg gtgcgtgagc acttgaaaac atttgccggt gttaaacgtc gtttcactga
    51181 gaaaattgtc aatgatacag tgattattga tgactttgcc catcatccaa cagaaattat
    51241 tgcgaccttg gatgcggctc gtcagaaata cccaagcaag gaaattgtag cagtctttca
    51301 accgcatacc tttacaagaa ccattgccct gttggacgac tttgcccatg ctttaaacca
    51361 agcagatgct gtttatctag cgcaaattta tggctcggct cgtgaagtag atcatggtga
    51421 cgttaaggta gaagacctag ccaataaaat caacaaaaaa caccaagtga ttactgttga
    51481 aaatgtttct ccactcctag accatgacaa tgctgtttac gtctttatgg gagcaggaga
    51541 catccaaacc tatgaatact catttgagcg tctcttgtct aacttgacaa gcaatgttca
    51601 ataggatgtt cccatggaaa ttccaattaa gatcattcag gcaagcaagt ttgatttgcc
    51661 tgagataggg gcacttcaga cctcgtcttt tccagctgaa aagcagcaac tttcccatat
    51721 tttagaagaa agtatccgta agtgtgcgga tacctttctt ctagctaggg atgaaaatca
    51781 acttttaggc tatattttat caagtcccca gtcagacaat ccgcaatgtc taaaagtaca
    51841 ttctttagtc atcgagtctg accatcagag acagggcctg ggaacacttc ttcttgcagc
    51901 cttgaaagag gtggcagttg agctggatta caaagggatt cgtttggaga gtcctgatga
    51961 gctgctttcc tattttgaaa tgaacggttt tgttgatgaa gaagaaactt tgctctatgc
    52021 aactagccag ggctatagta tgatttggtt taatcccttt tatctggagg aacaatgaaa
    52081 atcagacaag caagattaga agatttggat cggattgttg aacttgaatt tgaaaatttt
    52141 tcggtcgaag aagccattcc tccttctgtc tttgaagcac atttgagaga aattcagacc
    52201 tcttttctgg ttgctgaaaa agaaggaaga atcatgggtt atatcgaagg accagttggc
    52261 ctgcaccgcc atctgcaaga ccagtctttt acagaagaaa taaaagacta tagtcatgag
    52321 cctggtggtt atatctctgt gacctgtctg tctattgcca aggaggcaca gggactcgga
    52381 ctgggtcaga aattgctgac agccttgaaa gaagttgctc ttgaagatga gagagatggc
    52441 attaatctaa cctgtcatga ctatctcatc gcctattatg aaaaacatgg atttgtcaac
    52501 gaaggccagt cccagtcaac ctttgcaggg gaaacatggt atgatatggt ctgggaaatg
    52561 aaaaaataag ttaggaaaag tatcatagat tgcttttttt ggacttttaa gatataatat
    52621 tatggattat caacaaggag gaaaaacttt tgagtgaaaa gtcaagagaa gaagagaaat
    52681 taagctttaa agagcagatt ctgagagatt tagaaaaagt aaaaggctat gatgaagttc
    52741 tgaaagaaga tgaggcagta gttcgcactc ctgcaaatga accttcagct gaagaactca
    52801 tggctgattc cttgtcaacg gtagaggaga ttatgagaaa agctcctacc gtgcctactc
    52861 acccaagtca aggtgtacca gcttctccag cagatgagag tcaaagagaa actcctggtg
    52921 ttccaagtca tccaagtcaa gatgtacctt cttctccagc ggaagaaagt ggatcaagac
    52981 caggtccagg tcctgttaga cctaagaaac ttgaaagaga atacaatgaa accccaacaa
    53041 gggtagctgt ttcctatacg acggcagaga aaaaagcaga acaagcaggt ccagaaacac
    53101 ctacgcctgc tacagaaata gtggatatca tcagtgatac atcacgtcgt agccgtagag
    53161 aaggagcaaa acccgttaag cctaagaaag agaagaagtc acatgtgaaa gcttttgtga
    53221 tttcattcct tgtattcctt gccttgctct cagcaggtgg ttacttcggt taccagtacg
    53281 tgctagattc tttgttacct atcgatgcta attctaagaa atatgtgacg gttggaattc
    53341 cagaaggttc aaacgttcaa gaaatcggta cgacgcttga aaaagctggt ttggtaaagc
    53401 atggtctgat ttttagtttt tatgccaagt ataaaaatta taccgacttg aaagcaggtt
    53461 actacaattt gcaaaagagt atgagtacag aagacttact caaagagttg caaaaaggtg
    53521 gaacagatga accgcaagaa cctgtacttg cgactttgac aattccagaa ggttatacct
    53581 tggatcagat tgctcaagct gtgggtcaat tgcaaggtga cttcaaagag tctttgacag
    53641 cggaggcttt cttggctaaa gttcaagatg agacgtttat cagtcaagca gtagcgaaat
    53701 atcctacttt actggaaagt ttgcctgtaa aagacagcgg tgcgcgttat cgtttggaag
    53761 gatacctttt cccagctaca tactctatca aggaaagcac aactattgag agcttgattg
    53821 atgagatgtt agctgctatg gataagaacc tatctcctta ctatagtact atcaaatcta
    53881 aaaatttgac tgtcaatgag ttgttgacca ttgcttcctt ggtcgaaaaa gaaggtgcca
    53941 agacagaaga tcgtaagctc attgcaggtg tattctacaa tcgtttaaat cgtgatatgc
    54001 cacttcaaag taatattgca atcttgtatg cccaaggaaa actggggcaa aatatcagtc
    54061 tagctgagga tgttgcgatt gataccaaca ttgattcacc ttataatgtt tataaaaatg
    54121 taggtctcat gcctggtcca gtcgatagtc caagtctgga tgcgattgag tcaagcatca
    54181 atcaaactaa gagcgataac ctctactttg tagcagatgt cacagaaggc aaggtctact
    54241 atgctaacaa tcaagaagac cacgaccgca atgtcgctga acatgtcaac agcaaattaa
    54301 actaaacaaa ctaaaattat gtgatacgtc acataatttt ctttagaaaa tattatcaga
    54361 agaaagttga gaaaaatggc agaaaaaaca tatcctatga cccttgagga aaaggaaaaa
    54421 cttgaaaaag aattagaaga attgaaattg gttcgtcgac cagaagtggt agaacgcatt
    54481 aagattgccc gttcatacgg tgacctttca gaaaacagtg agtacgaagc agctaaggat
    54541 gaacaagcct ttgtcgaagg acaaatctct agcttagaaa caaaaatccg ctatgctgaa
    54601 atcgtcaata gcgacgcagt tgcccaggac gaagtagcga ttggtaaaac agtcaccatc
    54661 caagaaattg gtgaggacga agaagaagtt tatattatcg taggttcagc tggtgcggat
    54721 gcctttgcag gtaaggtttc aaatgaaagc ccaattgggc aggccttgat tggcaagaaa
    54781 acaggtgaca cagcaaccat tgaaacgcct gttggtagct atgatgtaaa aatcttgaag
    54841 gttgaaaaaa cagcctaaaa acagaaaaag gagtggggag gcgatgtgct tcactcactc
    54901 ctttttccat tttgctattc ttcgaaaatc tcttcaaacc acgtcagcgt cgccttgccg
    54961 tatgtatggt tactgacttt gtcagtttca tctacaacct caaaaccatg ttttgagctg
    55021 acttcgtcag tttcatctac aacctcaaaa ccatgttttg agctgacttc gtcagttcta
    55081 tctacaacct caaaacagtg ttttgagcaa cctgcggcta gtttcctagt ttgctctttg
    55141 attttcattg agtattagat gtatagtgca ttgaagttaa aatagtaaac tttgatttct
    55201 aagacattat tagaaattag attaaattcc ttaatcgatt tgcgcatgtt ttatttcatt
    55261 tcattatact ttagattgga aaataaggaa tcacataaat cgcaagaaat agggaatctg
    55321 attcgtgttt ataaccgttc aaaaagggaa gaggctgaaa gtgagccact taatctttat
    55381 gtcgaagatg aaaagggcaa tctccttgcg ggtttgatag cagagacttt tggaaattgg
    55441 ctagaaatcg agtatttgtt tgtaaaagag gaactgcgag ggcaaggaat cggttcaaaa
    55501 ctattgcaac aggcagaaag tgaagctaag aatcgaaatt gttgttttgc ctttgtcaat
    55561 acttatcagt tccaggcacc ggacttttat cagaaacatg gctacaagga agttttttct
    55621 ttgcaagact atctctacat taggcaaaga tattattacc aaaagaatct gtaaggtgag
    55681 tatggaggta taatacaaag agaggctcgc acataagtat ggaggtgtac tgatgtatat
    55741 gagtaactat cgataaatac cagttataac ctagaaattg tgtctttcta gacgatattg
    55801 aggacaatat aatcgtagct ccaaaattag gaatcaaggc ttatcaggtt aagaaaagaa
    55861 gtgatgttgt tgatatttta aaacaattta tttaaactaa aaactctcta tctttttaaa
    55921 ttgacattaa tccgagattc ccctctagga ttttgtgttg ctttcattaa atttacaggt
    55981 aagacttgct agcttcagta aatatacaca agtttttcag aatagagtga aatccgaaag
    56041 aaaatggaaa taatgaaaac tcttgtaggc ataagaaaac acctctgtgt tatacttgtt
    56101 gttcaaccac aaacacaaga aaggcacaga aatgcaagac aattatacta caaaagccaa
    56161 acatttgaca atcgatagcc gtcgcttaat cgaaagatgg aaaaaagaag ggaaatcaaa
    56221 tagagaaatt gcctctctac ttggaaaagc tcctcaaact atccacactg aaatcaagcg
    56281 tgggacagtc cgacaatgtc ttggaaaagg gcgcttcaaa gaggtttatt ctgccgacta
    56341 tgctcaacag tcttatgaaa acaatcgcaa gcgctcggtc aagaaatcaa gcgtgaccaa
    56401 ggaactaaag gaaaagattc tccactatca taaccaaaaa ttttcgcctg aaatgatggt
    56461 gatggctaaa ggggttaacg tgggaatttc aaccatttac tattggattc atcatggaaa
    56521 attggggtta agcaaacagg atctgcttta ccctagaaaa ggaaaagcgc ttaagaaaca
    56581 ggctagcacc aactttaaac ctgctggtca atccatcgaa cagcggtctg aagctatcaa
    56641 tcttcgcttg gagaatgggc attatgagat tgatacggtt ctacttacga gagcgaaaaa
    56701 ctactgcttg cttgtcttga cggatcgaaa gagtagacat cagatcatcc gattgattcc
    56761 aaataaaagt gctgaggtgg tcaatcaggc tctaaaactc atcttaaaac aacacaagat
    56821 tctttccatc acggcagata atggaacgga attcaatcgc ttgtttgatg tattttctga
    56881 ggagcacatt tattatgcgc acccctatgc cttttgggaa aggggaacta atgagaatca
    56941 caacaggttc attcgtagat ggttacctaa gggaaccaag aaaatgactc ccaaagaagt
    57001 cgcattcatc gaaaagtgga ttaacaacta tcctaaaaaa tgcttggact acaagtcacc
    57061 cagagaagac ttctggatgg ctaacttgaa cttgaaattt agcaaaatgg aaataatttt
    57121 tattaaacgc ttccaatagc ggttaaaagt tgacaaattt aaattttagg actacactaa
    57181 gtaagtaaat tttattttaa aggagaattt gttatgaatt taacattttt aggcttatgt
    57241 attgcctgta tgggcgtatc tgtcggtgaa ggtttattga tgaatggact gtttaaatca
    57301 gtagcacgcc aaccagatat gctttctgag tttcgtagtt tgatgttttt aggtgttgcc
    57361 tttattgaag gaactttctt tgtaactctt gtcttctcat ttattatcaa ataaatacat
    57421 ggaacgagaa gaaaagggag gattttagat ggaagaaagt attaatccaa tcatctctat
    57481 tggtcctgtt atcttcaatc tgactatgtt agccatgact ttgttgattg tgggagttat
    57541 ttttgtcttt atttattggg caagccgcaa tatgaccttg aaacccaaag gaaagcaaaa
    57601 tgtacttgag tatgtctatg actttgttat tggatttaca gaacctaaca ttggttcgcg
    57661 ctacatgaaa gattactcac tctttttcct ttgtttattc cttttcatgg tgattgccaa
    57721 taaccttggc ttaatgacaa agcttcaaac gatcgatggg actaactggt ggagttcgcc
    57781 aaccgctaat ttaccgtatg acttaacctt atcttttctt gtcattttgt tgacacatat
    57841 agaaagcgtt cgtcgtcgtg gatttaaaaa aagtataaaa tcttttatga gtcctgtttt
    57901 tgtcataccg atgaatatct tggaagaatt tacaaacttc ttatctttgg ctttgcggat
    57961 ttttgggaat atctttgcag gagaggtcat gacgagtttg ttacttcttc tttcccacca
    58021 agctatttat tggtatccag tagcctttgg agctaatttg gcttggactg cattttctgt
    58081 ctttatttcc tgcatccaag cttatgtttt tactcttttg acatctgtgt atttagggaa
    58141 taagattaat attgaagagg aatagaaagg agtaactgat gcacgtaaca gtaggtgaat
    58201 taattggtaa ttttatttta atcactggct cttttattct tttgctagtc ttgattaaaa
    58261 aatttgcatg gtctaatatt acaggcattt tcgaagaaag agctgaaaaa attgcttcag
    58321 atattgacag agctgaagaa gcccgtcaaa aagcagaagt attggctcaa aaacgcgaag
    58381 atgaattggc tggtagccgt aaagaagcta agacaatcat tgaaaatgca aaggaaacag
    58441 ctgagcaaag taaggctaat atcttagcag atgctaaact agaagcagga cacttaaaag
    58501 aaaaagcaaa ccaagaaatt gctcaaaaca aagctgaagc tttacaaagc gttaagggtg
    58561 aggttgcaga tttgaccatc agcttggctg gtaaaatcat ctcacaaaac cttgacggtc
    58621 atgcccataa agaactcatt gatcagtata tcgatcagct aggagaagct taatggacaa
    58681 gaaaacagta aaggtaattg aaaaatacag catgcctttt gtccaattgg tacttgaaaa
    58741 aggagaagaa gaccgtatct tttcagactt gactcaaatc aagcaagttg ctgaagaaac
    58801 aggtctgcct tcttttttaa aacaagtggc agtagacgag tcggataagg aaaaaacaat
    58861 tgcttttttc caagactctg tgtcaccttt aatacaaaac tttatccagg ttctggccta
    58921 caatcacaga gcaaatcttt tctatgatgt gattgtagat tgcttgaacc gacttgaaaa
    58981 agaaacaaat cgatttgaag tgacgattac gtctgctcat cctctaactg atgaacagaa
    59041 gactcgtttg ctccctttga ttgagaaaaa aatgtctctg aaagtaagga gtgtaaaaga
    59101 acaaatcgat gaaagtctca ttggtggttt tgtcattttt gccaatcaca agacaattga
    59161 tgtgagtatt aaacaacaac ttaaagttgt taaagaaaat ttgaaataga aagtggtgtt
    59221 cttttggcaa ttaacgcaca agaaatcagc gctttaatta agcaacaaat tgaaaatttc
    59281 aaacccaatt ttgatgtgac tgaaacaggt gttgtaacct atatcgggga cggtatcgcg
    59341 cgtgctcatg gccttgaaaa tgtcatgagt ggagagttgt tgaattttga aaacggctct
    59401 tatggtatgg ctcaaaactt ggagtcaaca gacgttggta ttatcatcct aggtgacttt
    59461 acagatatcc gtgaaggcga tacaatccgc cgtacaggga aaatcatgga agtccctgta
    59521 ggtgaaagtc tgattggtcg tgttgtggat ccgcttggtc gtccagttga cggtcttgga
    59581 gaaatccaca ctgataaaac tcgtccagta gaagcaccag ctcctggtgt tatgcaacgt
    59641 aagtctgttt cagaaccatt gcaaactggt ttgaaagcta ttgacgccct tgtaccgatt
    59701 ggtcgtggtc aacgtgagtt gattatcggt gaccgtcaga cagggaaaac aaccattgcg
    59761 attgatacaa tcttgaacca aaaagatcaa gatatgatct gtatctacgt cgcgattgga
    59821 caaaaagaat caacagttcg tacgcaagta gaaacacttc gtcagtacgg tgccttggac
    59881 tacacaatcg ttgtgacagc ctctgcttca caaccatctc cattgctctt cctagctcct
    59941 tatactgggg ttgctatggc ggaagaattt atgtatcaag gtaagcatgt tttgattgta
    60001 tacgatgatc tatcaaaaca agcggtagct tatcgtgaac tatcgctctt gcttcgtcgt
    60061 cctccaggtc gtgaagcctt cccaggggat gttttctatc tccacagccg tttgcttgag
    60121 cgctcagcta aagtttctga tgaacttggt ggtggatcaa ttacagccct accatttatc
    60181 gagacacaag caggagatat ctcagcctat atcgcaacca acgtgatttc tatcactgat
    60241 ggacaaatct tccttggcga tggcctcttc aatgcaggta ttcgtccagc catcgatgcg
    60301 ggttcatctg tatctcgtgt aggtggttct gcacaaatca aagccatgaa gaaggttgct
    60361 ggtacacttc gtatcgacct tgcttcatac cgtgagttgg aagcctttac taagtttggt
    60421 tctgacttgg acgcagcaac acaggctaag ttgaaccgtg gacgtcgtac cgttgaggtc
    60481 ttgaaacaac ctgttcacaa accattacct gttgagaaac aagtaaccat tctttatgct
    60541 ttgacacatg gtttcttgga tactgttcca gtagatgata ttgttcgttt cgaggaagag
    60601 ttccatacct tctttgatgc tcaacatcca gagattttgg aaaccattcg tgatacaaaa
    60661 gacttgccag aagaagcagt cttggatgct gcgattacag agtttctcaa tcaatctagc
    60721 ttccaataag aatagaggtg tcagatggca gtatctctaa atgatattaa aacaaaaatc
    60781 gcctcaacaa aaaatacgag tcaaatcact aatgccatgc aaatggtatc ggctgctaag
    60841 ctaggtcgtt ctgaagaagc tgctcgcaac ttccaagttt acgctcagaa agtgcgtaaa
    60901 cttttgacag atatccttca tggtaatgga gctggtgctt caactaatcc gatgttgatt
    60961 agccgttctg tgaagaagac aggctatatc gttatcactt cagaccgcgg tttggttgga
    61021 ggttataatt cctctatttt gaaagctgtt atggagttga aagaagaata ccacccagac
    61081 ggtaaaggtt ttgaaatgat ctgtatcggt gggatgggag ctgatttctt taaggctcgc
    61141 ggtattcaac cactttatga attacgtggc ttggcagacc aacctagctt tgatcaagtt
    61201 cgtaagatta tttcaaaaac tgttgaaatg taccaaaatg aactctttga tgagctttat
    61261 gtttgctaca accaccatgt caatacgcta accagtcaaa tgcgtgtgga acaaatgctt
    61321 ccgattgttg acttggatcc aaatgaagcg gatgaagagt acagcttgac ttttgaattg
    61381 gaaaccagcc gagaagaaat tctggagcag ttgttgcctc agtttgcaga aagtatgatt
    61441 tacggtgcca ttatcgatgc caagacagct gagaatgctg cgggtatgac agccatgcaa
    61501 acagcgacag ataatgctaa gaaagtcatc aatgatttga caattcagta taaccgtgcc
    61561 agacaggcgg cgattacaca agaaattaca gaaatcgtag caggtgctag tgccttagaa
    61621 taggctctag tccagctcgt atgaaaatga acttaggacc tagttgagct aggaaccgac
    61681 agtatcttat atagaatagg agaaggagat gagttcaggt aaaattgctc aggttatcgg
    61741 tcccgttgta gacgttttgt ttgcagcagg ggaaaaactt cctgagatta acaatgcact
    61801 tgtcgtctac aaaaatgacg aaagaaaaac aaaaatcgtc cttgaagtag ccttggagtt
    61861 aggagatggt atggttcgta ctatcgccat ggaatcaaca gatgggttga ctcgtggaat
    61921 ggaagtattg gacacaggtc gtccaatctc tgtaccagta ggtaaagaaa ctttgggacg
    61981 tgtcttcaac gttttgggag ataccattga tttggaagct ccttttacag aagacgcaga
    62041 gcgtcagcca attcataaaa aagctccaac ttttgatgag ttgtctacct cttctgaaat
    62101 ccttgaaaca gggatcaagg ttattgacct tcttgcccct taccttaaag gtggtaaagt
    62161 tggacttttc ggtggtgccg gagttggtaa aaccgtctta atccaagaat tgattcacaa
    62221 cattgcccaa gagcacggtg gtatttcagt atttactggt gttggggaac gtactcgtga
    62281 ggggaatgac ctttactggg aaatgaaaga atcaggcgtt atcgagaaaa cagccatggt
    62341 ctttggtcag atgaatgagc caccaggagc acgtatgcgt gttgccctta ctggtttgac
    62401 aatcgctgaa tacttccgtg atgtggaagg ccaagacgtg cttctcttta tcgataatat
    62461 cttccgtttc actcaggctg gttcagaagt atctgccctt ttgggtcgta tgccatcagc
    62521 cgttggttac caaccaacac ttgctacgga aatgggtcaa ttgcaagaac gtatcacatc
    62581 aaccaagaag ggttctgtaa cctctatcca ggctatctat gtgccagcgg atgactatac
    62641 tgacccagcg ccagcaacag ccttcgctca cttggattca acaacaaact tggaacgtaa
    62701 gttggtacaa ttgggtatct acccagccgt tgacccactt gcttcaagct cacgtgcctt
    62761 ggcacctgaa atcgttggag aagagcacta tgcagttgct gctgaagtaa aacgtgtcct
    62821 tcaacgttac catgaattgc aagatatcat tgctatcctt ggtatggatg agctttctga
    62881 tgaagaaaag accttggttg ctcgcgcccg tcgtatccag ttcttcttgt cacaaaactt
    62941 caacgttgcg gaacaattta ctggtcagcc aggttcttat gttccagttg ctgaaactgt
    63001 acgtggcttt aaggaaatcc ttgatggtaa atacgaccac ttgccagaag atgccttccg
    63061 tggtgtaggt tctatcgaag atgtgattgc aaaagctgaa aaaatgggat tttaagaggt
    63121 gatctatggc tcagttaact gtccagatcg tgacaccaga tggtctcgtc tatgatcacc
    63181 atgccagcta tgtatcggtt cgaactctgg atggtgagat ggggatcttg ccacgacatg
    63241 aaaatatgat tgcggtttta gcagttgatg aagtaaaggt aaaacgtatc gatgataaag
    63301 atcacgtgaa ctggattgca gtaaacggtg gcgttattga aattgccaat gatatgatca
    63361 caatcgtcgc tgactctgca gaacgtgctc gtgatatcga tatcagtcgt gcagaacgtg
    63421 ccaaacttcg tgcagaacgt gcaattgaag aagcacaaga caaacatttg attgaccaag
    63481 aacgtcgtgc taagattgct ttgcaacgtg ctattaaccg tattaatgtc ggaaatagac
    63541 tataagaaaa aatgaacttg aaaataccaa gttcattttt tatggtgttt taaggagcaa
    63601 aacggatgca gactgcttcg ggaacatgga agtcgttgga gagttctgct agacgaccat
    63661 tgtcacaatt acgtttaaag acagttgcat tgtcagagtc ttgatggaca acaatgagaa
    63721 atttttggtc gggtgtcaaa tcaaaatcac gtggagtctg accatgcgtt ggaacgattt
    63781 ctaataactc taagctaccg tccgcaagga tggtatatac tgcgatagaa tcatggccac
    63841 ggttagaagc gtagaggtat ttaccgtctt tagagagatg aatagcagcg gttccattaa
    63901 agccttcgta agcttccggt aaagttgaaa tgacctgcat acgttcaaat tcgccaacgc
    63961 catcgtagat taaaacttcg atagtactat tgagttcaca aatgagataa gcgattttat
    64021 agtggttatg gaaaatgata tggcgtgagc ctgctcctgg cttgctgtga taggtataga
    64081 gcttagataa ttttccttct tgatcgaggt cataggtgat gacttggtca gttcccaagt
    64141 cgcaggtcac tagatagtgg tcaggtgtta aatctgtata gtgaacatgg ggggaagctt
    64201 gattttcatg tggaccttgg ccactgtgtt gatccatatc actaagtaga agactaccat
    64261 cttcctggcg tttataaaca aggacttgtc ccttgtgata gttagctgcg taaaccaaat
    64321 cacgcttttc atcgacagca acataacagt ggggagctcc ttcttcaaca acatgattta
    64381 acacagtccc gtcagtttga taggctgcaa ttcccccctt atcgtcttgg ctaccaacag
    64441 tgtataaatg ttggtgctgg tcaaaggcaa ggtaggttgg acttggctca gctgcaaaaa
    64501 gttctagatt tgaaagctga ccagtttctg tatcaaagtc tgccttgtaa atcccttgag
    64561 aagtacgacg tgtataagtt ccaaaataaa cagtttcttt cattactata cctctgtgta
    64621 aagataagac tattatatca caaaaacaag taaattaaag atatccaatt agatgtaagc
    64681 actttaaaaa agagttattt tgtttcaaaa atggtataat gagagaacaa tagaaaggaa
    64741 gtatttatgg agcaaaaaga gaaacatttt agcctatctt ggtttttcaa gtggttttta
    64801 gataacaagg caattacggt atttttagta accttattat tgggactgaa tctttttatt
    64861 ttaagtaaga ttagttttct attttcacct gttttagact ttttagcagt tgtgatgttg
    64921 ccagtcattt tgtctggttt gttatattat ttgttgaatc ctattgttga ttggatggag
    64981 aagcataagg ttaatcgtgt tatagctatc actattgtct ttgttatcat cgctctcttt
    65041 atcatttggg gcttggcagt cgccattcca aatctgcaac gtcaggtttt gacctttgca
    65101 agaaacgttc ctgtttactt agaagatata gataggattg ttaatggatt ggtagcccag
    65161 catctgccag atgatttcag acctcaatta gagcaagttt tgaccaattt ttctagccag
    65221 gctacagttt tggcaagtaa ggtttcatct caggcagtca actgggtgag tgcctttatt
    65281 agcggggctt ctcaagtgat tgttgccttg attatcgttc ctttcatgct cttttatctc
    65341 ttgcgtgatg ggaaaggctt gcgtaactat ttgacccaat tcattccaag aaaattgaag
    65401 gaacctgttg gacaagttct atcagatgtg aatcaacagt tgtccaacta tgttcgaggg
    65461 caagtgacag tggctattat tgtagcagta atgtttatca tcttcttcaa gattattggt
    65521 ctacgctatg cggttacgct gggggttact gctggtattt taaatctggt cccttatctt
    65581 ggtagctttc tagccatgct tcctgctcta gtattgggtt tgattgctgg tccagtcatg
    65641 cttttgaaag tagtgattgt ctttatcgta gaacaaacta ttgaaggccg ttttgtctct
    65701 ccattgattt tgggaagtca attaaacatc caccctatta atgttctctt tgttttgtta
    65761 acttcaggat ctatgtttgg tatctgggga gttttacttg gtattccggt ttatgcctct
    65821 gctaaggttg tcatttcagc cattttcgaa tggtataagg tagtcagtgg tctatatgaa
    65881 ttagagggtg aggaagtcaa gagtgaacaa tagtcaacag atgttacagg ctttggagga
    65941 gcaagattta actaaggctg agcattattt cgccaaagct ttagaaaatg attcaagtga
    66001 tcttctgtat gagttggcaa cttatcttga agggattggt ttctatcctc aggccaagga
    66061 aatttacctg aaaattgtag aggattttcc agaggttcat cttaatctag ctgcaattgc
    66121 tagcgaggat ggtcaaatag aagaagcctt tacctatctt gaggaaatcc aagctgacag
    66181 tgactggtat gtctcgtctt tggctctgaa ggcagacctt taccagctgg aaggtttgac
    66241 agatgtggca cgtgagaaat tattggaggc cttgacctac tcagaggatt ctctcttgat
    66301 attgggtttg gcagagttgg atagtgagtt ggaaaattac caagcggcta ttcaagccta
    66361 tgcccagtta gataatcgct cgatttatga gcaaacgggc atttccacct atcaacgaat
    66421 tggctttgcc tatgctcagt tagggaaatt tgaaacggct actgagtttt tagaaaaagc
    66481 cctggagtta gaatacgatg acttaacagc ttttgagttg gccagtcttt attttgatca
    66541 agaagaatat caaaaagcca ccctctactt taagcagctt gataccattt ctcctgactt
    66601 tgaaggctat gagtatgggt acagtcaggc tttacataag gaacatcaag ttcaagaagc
    66661 cctgcgtatc gctaagcaag gattagagaa aaatcccttt gaaactcgcc tcttgctagc
    66721 tgcttcacaa ttttcttatg aattgcatga tgctagtggt gcagaaaatt atctccttac
    66781 tgcaaaagaa gacgctgagg atacagaaga aatcttgctt cgtttagcca ctatttatct
    66841 ggagcaggag cgttatgagg atattctaga cttgcagagt gaggagccag aaaatctttt
    66901 gaccaagtgg atgattgctc gttcttatca agaaatggac gatttggata ctgcttatga
    66961 gcattatcaa gagttgacag gagatttgaa ggacaatcca gaatttctgg aacactatat
    67021 ctatctcttg cgtgaattgg gacattttga agaagcaaaa gtccatgctc acacttactt
    67081 aaaactggtt ccagatgatg tgcaaatgca agaactgttt gagagattgt aagaatgttt
    67141 aaacatatag aactgtagtt tatctctttt gatagctacg gtttttattt gtatatggta
    67201 gaatcttttt acaaaaatac ttggtaatct tgtttattca tgctataata ggaacaatta
    67261 cttttaggag gtgcagtatg tcttatttat ttgagatatt accgagttta ctgaatggtg
    67321 cgagcacgac tgtacaggtc tttgcactgg tcttgctatt ttcgattccc ttgggcgttt
    67381 tgattgcctt tgccttgcaa gtccattgga agcccctcca ttatctgatt aacatttaca
    67441 tctgggttat gcgaggaacc cccttactct tgcaactgat ttttatctat tatgtgctcc
    67501 caagtattgg gattcgttta gaccgccttc ctgcagctat tattgccttt gttctcaact
    67561 atgcagctta ctttgcagaa attttccgtg ggggaattga cactattcca agaggacagt
    67621 atgaggctgc caaggtcttg aagtttagcc cttttgacag agtgcgctat attatcttgc
    67681 cccaagtgac caagatcgtt cttcctagtg tctttaatga agttatgagt ttggtcaagg
    67741 atacttcttt ggtctatgct ctcggaattt cagaccttat cttggctagt cgaacagctg
    67801 ctaaccgcga tgctagtctg gttcctatgt tcttggcagg agccatttac ttgattttaa
    67861 ttgggattgt gacaattatt tccaaaaaag ttgagaaaaa gtacagttat tatagatagg
    67921 gggcagctat gttagaatta cgaaatatca ataaagtctt tggagacaaa caaatcctgt
    67981 ctgatttcag tctaagtatt cctgaaaagc aaatcctggc tatcgttgga ccttctggtg
    68041 gaggtaagac aactctttta cgtatgcttg caggtcttga aaccattgat tcagggcaaa
    68101 tcttttataa tggacaacct ttagagctag atgaattgca gaagcgcaac ctactgggat
    68161 ttgtcttcca agattttcaa ctatttcctc atctatcagt tctggaaaat ttgactttat
    68221 cgcctgtgaa gaccatggga atgaagcagg aagaggctga gaagaaggcg agtggactct
    68281 tggaacagtt aggactagga ggacacgcag aggcctatcc tttctcacta tctggtgggc
    68341 aaaagcagcg ggtggctttg gcgcgtgcta tgatgattga cccagaaatc attggctacg
    68401 atgaaccaac ttctgccctg gatccagaat tacgtttgga agtggagaag ctaatcttgc
    68461 aaaataggga acttgggatg acccagattg tggttaccca tgatttgcag tttgctgaaa
    68521 atatcgcaga tgtattattg aaagtagaac ctaaatagga ggaaaaatgg atgaaaaaat
    68581 ggatgcttgt attagtcagt ctgatgactg ctttgttctt agtagcttgt gggaaaaatt
    68641 ctagcgaaac tagtggagat aattggtcaa agtaccagtc taacaagtct attactattg
    68701 gatttgatag tacttttgtt ccaatgggat ttgctcagaa agatggttct tatgcaggat
    68761 ttgatattga tttagctaca gctgtttttg aaaaatacgg aatcacggta aattggcaac
    68821 cgattgattg ggatttgaaa gaagctgaat tgacaaaagg aacgattgat ctgatttgga
    68881 atggctattc cgctacagac gaacgccgtg aaaaggtggc tttcagtaac tcatatatga
    68941 agaatgagca ggtattggtt acgaagaaat catctggtat cacgactgca aaggatatga
    69001 ctggaaagac attaggagct caagctggtt catctggtta tgcggacttt gaagcaaatc
    69061 cagaaatttt gaagaatatt gtcgctaata aggaagcgaa tcaataccaa acctttaatg
    69121 aagccttgat tgatttgaaa aacgatcgaa ttgatggtct attgattgac cgtgtctatg
    69181 caaactatta tttagaagca gaaggtgttt taaacgatta taatgtcttt acagttggac
    69241 tagaaacaga agcttttgcg gttggagccc gtaaggaaga tacaaccttg gttaagaaga
    69301 taaatgaagc tttttctagt ctttacaagg acggcaagtt ccaagaaatc agccaaaaat
    69361 ggtttggaga agatgtagca accaaagaag taaaagaagg acagtaagat aaaatagtgg
    69421 ctgaaactgc gttttgatta gcaaaacgta gtttttttgt aatctaggaa aacgataata
    69481 gcgattgaat atggataatt gaatatggaa tagcccactg tgatttctaa aacattgtta
    69541 aaaattgatt tgacttccaa aattaaaatg ttctgtaatg aaatgctgat gtaactgttt
    69601 taggaacaat aaaacgcata atatcaaggt ttttgcacct tacattatgc gtttttgtga
    69661 ttttaagact tgttagctga ttttttacaa tcctgcgaaa tctttgattt cttgtgctga
    69721 cattgaagag tcgcaacgga cgttgatttg tccatctgta atatgaacaa aacctggtac
    69781 agttgggatt ccatagcgtg agcggaatgc ttgcaaatca ttgagttggc ttggttcttc
    69841 actattgatg aagtaaatgt gagctttggt ttcagctacg acacctgaca atgtatctgc
    69901 aaatttacgg cagtaagggc aagttttgcg accgataaag aaggttgcag tttctttttt
    69961 atcaagagct tcttgcgcac gcacaactgt agtgacttca aggtctttga tgttatctaa
    70021 aaattgttcc atgagattac ctcgctttca ttgataagtc tagtatgcca taaagtttct
    70081 aaaattgctt agatttgata cgaaaaaaga tgaggttggt tggtctcatc ttttataggt
    70141 ctttatttta caaatgcatt gatttctgct tcgatgttag caatcttagc ttgtgattct
    70201 tcgttggttt cccctacaac tgcaatgtag aacttgattt ttggttctgt acctgaaggg
    70261 cgaacggcaa tccatgaacc gtcagcaagt gtgtatttca acacatcact tggaggagtt
    70321 gtcaagtttg taacagtacc gtcagcaaca gtagcagttt gtgccttgaa gtcttctacg
    70381 acagtgatag ctgtttcgtt ccattctttt ggagcattgt tgcggaattt agccataatc
    70441 gctttgattt gttcagcacc atcgacacct gaaagagtaa cagagattgt tttttctgcg
    70501 tagtagccat attctttata gatttcttcg ataccgtcag caagtgtcaa accacgagaa
    70561 cggtagtagg cagcaagttc agcaacgaca agaacggctt ggatggcatc tttatcacgt
    70621 acaaatggtt taatcaagta accgaagctt tcttcaaatc ccatcatgta agtgtggttg
    70681 tgtttttctt cgaattcttg gattttttca gcgataaatt tgaaacctgt caagacgttg
    70741 aacatagttg cgccgtagct ttcagcaatc ttcgttacca agtcagttga aacgatagat
    70801 ttgcagagag cggcattttc aggaagagtt ccagcgtttt tgtgagcttc caagatgtat
    70861 ttagccatga tagcaccgat ttggttacct gaaaggttga ggtagctacc atctttttga
    70921 agaacttcaa caccaacacg gtcagcgtct gggtcagttg cgacaagaac atctgcacca
    70981 acttgacgac caagttcttc agcaagggca aaggctgctt ggctttctgg gtttggagat
    71041 gttacagttg agaagtctgg gtcagcagtt gcttgcgctt caacaacttg aacagagtca
    71101 aatcctgctt gggcaagagc acgacgagcc aacatttcac cagtaccatg aagtggtgtg
    71161 tagacaatct tcatgtcttt accaaattct tcaatcaagg ctgggttgat gtttatgtcc
    71221 ttaacctctt taaggtattc tatgtcaaca gcttcgccga taacttcaat caagccagaa
    71281 gctttttcag tttccacatc agcaacttca actgcaaatg ggttttcgat tgcacggata
    71341 taagtagtca aagcgtccgc atcgtgtgga ggcatttgtc caccgtcttc accgtaaacc
    71401 ttgtaaccgt taaatggagc agggttgtgg ctggctgtga ccatgatacc tgcgaaacag
    71461 ttgagatgac gaactgcaaa tgatagttct ggagttggac gaaggctttc aaatacgtaa
    71521 gatttgatgc cgtgtttagc aagaactgcc gcagattcaa aggcaaactc aggtgagaag
    71581 tgacggctat cgtaggcaat tgctacaccg cgttctttct cgtttccacc ttttgactca
    71641 atcaaacgag ccaatccttc agtagcttgg cgaacaacgt agatgttgat acggtttgta
    71701 ccagcaccaa ccaagccacg catacctgca gtaccaaatt caagatttgt atagaaggca
    71761 tcttccttag ttttttcgtc catattttcc aaatcttgac gaaggtagtc aggaagctcc
    71821 acaaaatcaa cccatttctg gtaattttct tggtaagaca ttcaaattct cctttatttt
    71881 taaaacattt aatcagtttg attatatcat tttttttagt tttagtaaaa ccttatctgc
    71941 ttcgaacatc tcttcaaacc aggtcagatt gaattttggg gttatatgat gttgaggtta
    72001 ggaaaaattc gatttcagta aaaaaagtaa gtcttctaat aacaaaacat tgatatagtt
    72061 gcttagtttt aaacaagcat attataataa agctatggca tatagtactg attttaaaca
    72121 gcgagcatta gattacatca aagaggggca cagccatgtc gaggcagcca agttttttgg
    72181 tgttggcgtc agaactctct tcacgtggga aaagaaagat gtgaacaagg acacatagag
    72241 aggaaaaagc gagtcgtcaa aaaccgaaag attcctttag aggaattgaa agcctttgta
    72301 gaggctcatc cagatgcttt tttacgggaa attgcggcac attttgattg tgctgttcct
    72361 tcagtatggg cagctttaaa gcagattaag gtcactttaa aaaaagatga cgagctttaa
    72421 ggaacaagag ccagagaaag tcgctgagtt tcttgatatt ttggataacc taaaaaattt
    72481 accaatcgta tatattgacg aaacaggaat cgaccgctac ctctatcgtc cttatgcagg
    72541 ggctcctaga ggggagaaag tctatgaaaa gattagcgga cgtcgttttg agcgaacttc
    72601 aattgttgca ggacaagtag acggagagtt tatagctccc atgatttaca agaaaagcat
    72661 gacaagcgat ttctttgtgg agtggttcaa aacgcaactc ctacctgctt tgaagacacc
    72721 tcatgttatt gtcatgggca atgctagttt tcatcccaag aacattttgg atgaactctg
    72781 catccaagat aaacactttt tcttacctct accaccttat tcaccggatt tgaatcctat
    72841 tgagcaagct tgggctatct tgaaaaagaa agtgacggat ttattaaggg aagttccaac
    72901 tatttttgaa tgtttggaat gcttttttaa aactagatga ctataacggt tctaaaggaa
    72961 cctatcgagt agtcattaaa actaaggata ctgctggtta agagaagacg gtatacgatc
    73021 aaaccattca ccgtgtagcc gaaatcgttc agaatgaaga cttgtataag aaaggtttga
    73081 atgttgaact tgcgcaccaa caaattaagg gattttttga agcagaattt aaaaatcgta
    73141 ttaatggagt tcttaatact aaaataaaaa atagtacatt aaatcgtgta aataaaaaaa
    73201 ctatacacca gagcaacaaa aactccatga tcaatttgaa gcagaagcaa cggaagatgc
    73261 taaaaaacaa ggcgatattg tgttgaatgt tgaccaggat ttcatgagca tatctaagtc
    73321 taataaaagt ggttcagact ggaagaaaac tttcacagtg aggacaacca ataggttagc
    73381 aaatgacttg aataatgtct tgaaacaggc tgataaagat actcctaata ccccaatttg
    73441 gctaaactca gctgcttcta aagctaaaga tgatgacaga gcatataaac tactgaagac
    73501 tcttatacca ggagaaaatt acctatcatg ttaaggataa tcagctagaa gtagaaacag
    73561 ataaatacac atatactgcc gctagaaatg gtagtaagga agttggtatt caagagtcag
    73621 atatagcagc aactctaagt gccgatgaat ataattctaa tcgccaaacc tttgagagag
    73681 aatacaaata caaaagcaaa tgcccttaat aatggttggg ctagatctgg ttctgaagag
    73741 ttcaaaaagt tctcccactt tgtaggggta gacaaaggga ttgtgcgaac gaatgtactg
    73801 actggtaaaa aactatctga taagattagg aaagaagtgg actctggaga tagcaaacta
    73861 ggaaaaggcg gctatttctc tactggggat gttctattag gaaaagatgt tgtttcttat
    73921 accgtacaag tattttcaga gaataatgaa agagtaggag taaacactca aagtcaccgt
    73981 gttcagtata atctcccaat tctagctgac ttttcagtca tccaagatat tgtggaacca
    74041 tcacgaaccg ttgttgaaaa aatcattcca aaactaaata ttcccgaaga agagaaaaag
    74101 aaaaaaacct cagaattggc agaactaatc tcagaaaatg tgaaagtttg ctatgttgat
    74161 gaacaagggc gtttgctatc attgaaaaat gatactggaa ttggagaaaa agaaagtgac
    74221 ggaacttaca ttaccaataa aaaacaactg attggtacca gctataatgt cacagataaa
    74281 aaactcagta gcatgactac tactgacgga aaatattata cttttaaaga agcagataca
    74341 aattctgcaa gtttaactgg gaatattgta agcgaaggta gaacagtgac cttagtttat
    74401 agagaaagcg aagcgccaac cactgctaca gtaacagcca attactataa agaaggtagc
    74461 caagagaagt tggcagagtc tgttataaaa gctgatttag cgataggttc tgagtatacc
    74521 acagaatcaa aaactattga agggaaaaca acaactgagg acaaagaaga ccgagttatc
    74581 acaaggaaaa caacatacac cttggtagca actcctgcaa atgcgtacca gaagacggtg
    74641 caacagttga ctattactac cgtgagaatg ttgaggaaac agtggttccc aaaacagcaa
    74701 cctctactga gacgaagact ataacgcgta tcattcatta cgttgataaa gttacgaacc
    74761 aaaatgtaaa agaagatgtt gttcaacctg taaccttaag ccgtacaaaa actgagaaca
    74821 aggtcacggg agttgtaacc tacggtgaat ggacaacagg aaactgggac gaggttatat
    74881 ctggtaagat tgacaagtac aaagatccag atattccaac agttgaatca caagaagtta
    74941 cgtcagactc tagtgataaa gaaataacgg taaggtatga ccgtttatca acaccagata
    75001 aaccaactcc agaaaaacca gaaattccaa gtcctcagga accaggtact ccaggtgaac
    75061 cgactccaga aaaaccaatc ccacaaccaa atccagagca tccaagtgtt ccgacaccaa
    75121 acccagaact accaaatcaa gagactccaa taccagagcc aactccagaa ccaggtactc
    75181 caaaaactga aactccagtg aatccagacc cagaagttcc gacttatgag acaggtaaga
    75241 gagaggaatt gccaaacaca ggtacagaag ctaatgctac cttggctagt gctggtatca
    75301 tgaccttgtt agctagtcta gtattaggat tcttcaagaa aaaagaagat gaaaaataat
    75361 agattttaga atctaggaac caggaaaagc tcacagatgt gggctttttt cctggttttg
    75421 agaacgaggt ctttcgtgaa gaataaaaac gcttacaagt acgttgaact gggaaactat
    75481 gaatcctatt tttttaaaaa tatttccaga aatcagttgc taaatagggt aaaaattgat
    75541 aaaataagga atatctaaaa aattttaagg agaatctagc aaatggattt cacatgggca
    75601 ctgaagtatg ccactgaatt tttgggaact gccattttga tcattcttgg gaatggtgca
    75661 gttgccaacg ttgaacttaa aggtacgaaa ggtcaccaaa gtggctggat cgtcatcgct
    75721 gttggttatg gtatgggggt tatgatccca gccttgatgt ttggtaacgt atctgggaat
    75781 cacatcaacc ctgctttcac tctagggctt gcagttagcg gtcttttccc ttgggcacaa
    75841 gtggtacctt acattatcgc gcaagtcttg ggggctatct ttggccaagc cttagttgtg
    75901 gcaacatacc gtccattcta cttgaaaact gaaaaaccaa ataacatctt gggaactttc
    75961 tcaactattt caagtattga ccatggtaca aaagaaagtc gctatgcagc aactgtcaat
    76021 ggtttgatta atgagtttgt tggttcattt gttttgttct ttgcagctct tggtttgact
    76081 aaaaacttct ttggtgctga agtgcttcaa ttcatgaaac aaaaggcaat agaagcagga
    76141 caaacagttg atttttctga cttggctatt aaagcacagg tggctccaca cactgcttca
    76201 ggactttctg tggctcactt ggcacttgga ttcctcgtta tggctttggt aacatcactt
    76261 ggaggaccta caggacctgc cttgaaccca gcccgtgact tgggaccacg tctccttcat
    76321 gctttccttc caaaatcagt tcttggtgag cataaaggcg attcaaaatg gtggtattct
    76381 tgggtaccag tagtagcacc tatcgcagca gcaattgcgg cagtagctgt attcaaattc
    76441 ctttatctct aagaaatagc tcctttaaca tttgagtgag caccatctat aagtaagaga
    76501 ggatcagact ggttctctct ttttgatttt ttagggaaat gaaagaaact ctaaacaaac
    76561 tcctctccag cagtggttta gaagtttcag tgggctattc cagcttcaat gggctatagt
    76621 aggttgcagt tgaaataata gacccttgtt tctaaaacat tgttagaaat tggtttgaat
    76681 tctccaatca aattgtgcag ttttcattct actatatatt atcggagatg ggttccctat
    76741 cttgtaagtc tgctttatag tggattgaag ttggaatagt ccccccttct ttctcaaaca
    76801 ttgtgaggaa ttgatttacc ttcctcaaca aaatgttcag tttctatttc attttgctat
    76861 aaaataagcg attagggggg ctattcttcg acctacattg actctgctga gtcctatgat
    76921 tgttatcgtt ttatctgcaa ttttatactc aatgaaaatc aaagggcaaa ctaagaagct
    76981 agccgcaggt tgttcaaaac acagttttga ggttgtatag tagattgaaa ctagaatagt
    77041 acacatctac ttctaaaaca ttgttagaaa tcgatttgac tgtcctgatc gatttgccct
    77101 attcttgttt cattttacta tataaaccag agactgttta cattttcagc aagtgagtgg
    77161 atggataatg ctgaaaactc cttgaaggat aagtctattt agtactttct attaattagt
    77221 taaattttta ccaagaataa ttcacaaaaa cgttgtaaaa cacttgcaat ttagctgaaa
    77281 tttgataaaa tagtaaggaa agttagactg tattgcctac tgtctatcta taaaatatat
    77341 tttattggag gcttttactc aaatggcaaa agaaaaatac gatcgtagta aaccacacgt
    77401 taacattggt actatcggac acgttgacca cggtaaaact accctaactg cagctatcac
    77461 aactgttttg gcacgtcgct tgccttcatc agttaaccaa cctaaagact atgcgtctat
    77521 cgatgctgct ccagaagaac gcgaacgcgg tatcactatc aacactgcgc acgttgagta
    77581 cgaaactgaa aaacgtcact acgctcacat cgacgctcca ggacacgcgg actacgttaa
    77641 aaacatgatc actggtgctg ctcaaatgga cggagctatc cttgtagtag cttcaactga
    77701 cggaccaatg ccacaaactc gtgagcacat ccttctttca cgtcaggttg gtgttaaaca
    77761 ccttatcgtc ttcatgaaca aagttgactt ggttgacgac gaagaattgc ttgaattggt
    77821 tgaaatggaa atccgtgacc tattgtcaga atacgacttc ccaggtgacg atcttccagt
    77881 tatccaaggt tcagcactta aagctcttga aggtgactct aaatacgaag acatcgttat
    77941 ggaattgatg aacacagttg atgagtatat cccagaacca gaacgtgaca ctgacaaacc
    78001 attgcttctt ccagtcgagg acgtattctc aatcactgga cgtggtacag ttgcttcagg
    78061 acgtatcgac cgtggtatcg ttaaagtcaa cgacgaaatc gaaatcgttg gtatcaaaga
    78121 agaaactcaa aaagcagttg ttactggtgt tgaaatgttc cgtaaacaac ttgacgaagg
    78181 tcttgctgga gataacgtag gtgtccttct tcgtggtgtt caacgtgatg aaatcgaacg
    78241 tggacaagtt atcgctaaac caggttcaat caacccacac actaaattca aaggtgaagt
    78301 ctacatcctt actaaagaag aaggtggacg tcacactcca ttcttcaaca actaccgtcc
    78361 acaattctac ttccgtacta ctgacgttac aggttcaatc gaacttccag caggtactga
    78421 aatggtaatg cctggtgata acgtgacaat cgacgttgag ttgattcacc caatcgccgt
    78481 agaacaaggt actacattct ctatccgtga gggtggacgt actgttggtt caggtatggt
    78541 tacagaaatc gaagcttaat tcgatttagt tcccagaaga acaattattt aagtcagaca
    78601 ctaaaagaat cttgcttggc aaggttcttt ttttagatat tgaactaata ctcaatgaaa
    78661 atcaaagagt aaactataat agattgaaac tagaatagta cacatctact tctaaaacat
    78721 tgttagaaat caatttgact gtcctgatcg atttgtcttg ttcttatttc attttactat
    78781 agaaagttag ttacagactg ctcaaaacac tgtttttagg ttgtagatag aactgacgaa
    78841 gtcagtaaca tctatacgac aaggcgaagc tgacgcggtt tgaagagatt ttcgaagagt
    78901 ataatactag actaaaatca aaaagcatta tacaatagta atatgaaatc aattaaagaa
    78961 gaaatccaaa ccatcaaaac acttttaaaa gactctcgta cagctaaata tcataaacgc
    79021 cttcaaatcg ttctatttcg tctgatgggc aaatcttata aagagattat agagctttta
    79081 gactgtaatc aaacaacgat ttggcgaaat gtaaaaaaat atgaggagtt cggactcgac
    79141 tctctccttc aagaaacacg tggtggtcgt aaccatcata tatgacagtt gaggaagaaa
    79201 aagcctttct tgcccgccat ttgaaggctg cagaggcagg agaatttgtt acaattgatg
    79261 ccttatttca ggcttataaa aaggagttag gtcgttccta cacacgtgat gccttctatc
    79321 aactgttgaa gcgccatggt tggcgaaata ttacgccacg tccagaacat ccta
//
LOCUS       DAVLXH010000003        74480 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00028199
            SAMN33607166-rid17955573.denovo.003, whole genome shotgun sequence.
ACCESSION   DAVLXH010000003 DAVLXH010000000
VERSION     DAVLXH010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607166
            Sequence Read Archive: SRR23725544
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 74480)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 74480)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721421.1
            Genome Coverage       :: 115x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:42:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,210
            CDSs (total)                      :: 2,161
            Genes (coding)                    :: 2,023
            CDSs (with protein)               :: 2,023
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 73 of 138
            Pseudo Genes (incomplete)         :: 60 of 138
            Pseudo Genes (internal stop)      :: 40 of 138
            Pseudo Genes (multiple problems)  :: 31 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..74480
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607166-rid17955573.denovo.003"
                     /strain="AUSMDU00028199"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1349"
     gene            101..3202
                     /locus_tag="VYO11_000185"
     CDS             101..3202
                     /locus_tag="VYO11_000185"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000561528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HEV1594813.1"
                     /translation="MIAQLDTKTVYSFMESVISIEKYVRAAKEYGYTHLAMMDIDNLY
                     GAFDFLEITKKYGIHPLLGLEMTVFVDDQEVNLRFLALSSVGYQQLMKLSTAKMQGEK
                     TWSVLSQYLEDIAVIVPYFDRVESLELGCDYYIGVYPETLASEFHHPILPLYRVNAFE
                     SRDREVLQVLTAIKENLPLREVPLRSRQDVFISASSLEKLFQERFPQALDNLEKLISG
                     ISYDLDTSLKLPRFNPARPAVEELRERAELGLVQKGLTSKEYQDRLDQELSVIHDMGF
                     DDYFLVVWDLLRFGRSNGYYMGMGRGSAVGSLVSYALDITGIDPVEKNLIFERFLNRE
                     RYTMPDIDIDIPDIYRPDFIRYVGNKYGSKHAAQIVTFSTFGAKQALRDVLKRFGVPE
                     YELSAITKKISFRDNLKSAYEGNLQFRQQINSKLEYQKAFEIACKIEGYPRQTSVHAA
                     GVVISDQDLTNYIPLKYGDEIPLTQYDAHGVEASGLLKMDFLGLRNLTFVQKMQELLV
                     ETEGIHLKIEEIDLEDKETLDLFASGNTKGIFQFEQPGAIRLLKRVQPVCFEDVVATT
                     SLNRPGASDYINNFVARKHGQEEVTVLDSALEDILAPTYGIMLYQEQVMQVAQRFAGF
                     SLGKADILRRAMGKKDASAMHEMRASFIQGSIEAGHTAEKAGQVFDVMEKFAGYGFNR
                     SHAYAYSALAFQLAYFKTHYPAIFYQIMLNSANSDYVTDALEAGFEVAPLSINTIPYH
                     DKIANKSIYIGLKSIKGLSKDLALWIIEHRPYSNIEDFIAKLPENYLKHPLLEPLVKV
                     GLFDLFEKNRQKVFNNLANLFEFVKELGSLFGDAIYSWQESEDWTEQEKFYMEQELLG
                     IGVSKHPLQAIASKAIYPITPIGNLSENSYAIILVEVRKIKVIRTKKGENMAFLQADD
                     SKKKLDVTLFSDLYRQVGQEIKEGAFYYVKGKIQSRDGRLQMIAQKIREAVAERFWIQ
                     VKNHDSEQEMSRILDQYKGPIPVIIRYEEEQKTIVSPHHFVAKSDELEAKLNGIVMKT
                     IYR"
     gene            3284..4291
                     /gene="pfkA"
                     /locus_tag="VYO11_000186"
     CDS             3284..4291
                     /gene="pfkA"
                     /locus_tag="VYO11_000186"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HEV1594814.1"
                     /translation="MKRIAVLTSGGDAPGMNAAIRAVVRQAISEGMEVFGIYDGYAGM
                     VAGEIHPLDVASVGDIISRGGTFLHSARYPEFAQLEGQLKGIEQLKKHGIEGVVVIGG
                     DGSYHGAMRLTEHGFPAIGLPGTIDNDIVGTDFTIGFDTAVTTAMDAIDKIRDTSSSH
                     RRTFVIEVMGRNAGDIALWAGIATGADEIIIPEAGFKMEDIVASIKAGYECGKKHNII
                     VLAEGVMSAAEFGQKLKEAGDTSDLRVTELGHIQRGGSPTARDRVLASRMGAHAVKLL
                     KEGIGGVAVGIRNEKMVENPILGTAEEGALFSLTAEGKIVVNNPHKADIELSSLNKSL
                     S"
     gene            4350..5855
                     /gene="pyk"
                     /locus_tag="VYO11_000187"
     CDS             4350..5855
                     /gene="pyk"
                     /locus_tag="VYO11_000187"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HEV1594815.1"
                     /translation="MNKRVKIVATLGPAVEIRGGKKFGEDGYWGEKLDVEASAKNIAK
                     LIEAGANTFRFNFSHGDHQEQGERMATVKLAEKIAGKKVGFLLDTKGPEIRTELFEGE
                     AKEYSYKTGEKIRVATKQGIKSTREVIALNVAGALDIYDDVEVGRQVLVDDGKLGLRV
                     VAKDDATREFEVEVENDGIIAKQKGVNIPNTKIPFPALAERDNDDIRFGLEQGINFIA
                     ISFVRTAKDVNEVRAICEETGNGHVQLFAKIENQQGIDNLDEIIEAADGIMIARGDMG
                     IEVPFEMVPVYQKMIIKKVNAAGKVVITATNMLETMTEKPRATRSEVSDVFNAVIDGT
                     DATMLSGESANGKYPLESVTTMATIDKNAQALLNEYGRLDSDSFERNSKTEVMASAVK
                     DATSSMDIKLVVTLTKTGHTARLISKYRPNADILALTFDELTERGLMLNWGVIPMLTD
                     APSSTDDMFEIAERKAVEAGLVESGDDIVIVAGVPVGEAVRTNTMRIRTVR"
     gene            complement(6171..6419)
                     /locus_tag="VYO11_000188"
     CDS             complement(6171..6419)
                     /locus_tag="VYO11_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001167984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEV1594816.1"
                     /translation="MQKANTKLEKPINQPLSSHIFRHTLLSTLAEKNAIMVRVEHKNA
                     KTVNNIYTHVSKRMEQATLEVLNTISLNRKYIRSNLDK"
     gene            complement(6585..7346)
                     /locus_tag="VYO11_000189"
                     /pseudo
     CDS             complement(6585..7346)
                     /locus_tag="VYO11_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001107579.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            7658..8530
                     /locus_tag="VYO11_000190"
     CDS             7658..8530
                     /locus_tag="VYO11_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4300 family protein"
                     /protein_id="HEV1594817.1"
                     /translation="MKKSRKLATLGICSALFLGLAACQQQHATSEGTNQRQSSSAKVP
                     WKASYTNLNNQVSTEEVKSLLSAHLDPNSVDAFFNLVNDYNTIVGSTGLSGDFTSFTH
                     TEYDVEKISHLWNQKKGDFVGTNCRINSYCLLKNSVTIPKLEKNDQLLFLDNDAIDKG
                     KVFDSQDKEEFDILFSRVPTEATTDVKVHAEKMETFFSQFQFNEKARMLSVVLHDNLD
                     GEYLFVGHVGVLVPADDGFLFVEKLTFEEPYQAIKFASKEDCYKYLGTKYADYTGEGL
                     AKPFIMDNDKWVKL"
     gene            complement(8676..9020)
                     /locus_tag="VYO11_000191"
                     /pseudo
     CDS             complement(8676..9020)
                     /locus_tag="VYO11_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            9163..9474
                     /locus_tag="VYO11_000192"
     CDS             9163..9474
                     /locus_tag="VYO11_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1594818.1"
                     /translation="MELKDFTEKEQEMIKKRLTMSNISDKETTEKILALVPQDLIKRI
                     PFFVRKHATTRTIKRISIEHPELYAVAQTSGEIPEKEREELRQIITTIFEQKMNKHSI
                     K"
     gene            9478..10194
                     /locus_tag="VYO11_000193"
     CDS             9478..10194
                     /locus_tag="VYO11_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEV1594819.1"
                     /translation="MKKYFISGLGSNAYHSKDFFQELDSQVYFLNPYEKHLRDETELK
                     SWFKNEIVEEESICLIGHSLGGDLARYFASEFEEVKKLILLDGGYLDLDKILPLDTEL
                     EETKNYIKSQIVLDLDVLTSKEKSEAKHWSENMEKAVRQSYHWNVEYNRYELAINYEN
                     IEAILRLRRKIQAFKREVGDTLFISPRYPNGATWREEALKELPDYFDTIFLENFGHEL
                     YTQAPKEISSLMNEWLAYFL"
     gene            complement(10324..11139)
                     /locus_tag="VYO11_000194"
     CDS             complement(10324..11139)
                     /locus_tag="VYO11_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000617844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HEV1594820.1"
                     /translation="MIRFLVLAGYFELTIYLHLSGKLNQYINMHYSYLAYISMVLSFI
                     LAIVQLYIWMKQVKTHSHLNSRLAKMTSISLLAIPLVIGLTFPTVSLDSQTVSAKGYH
                     FPLSEGTDLAIQTSEGTTSQYLKPDTSSYFSKSAYEKEMRTAADKYLSQDSIQITNEN
                     YMEVMEAIYDYPDEFEGKTIQFTGFVYNDPSHANSQFLFRFGIIHCIADSGVYGLLTK
                     GNTRQYENNTWITAKGKLVNHYHKELKQNLPTLEIDSFTKVDKPENPYVYRAF"
     gene            complement(11136..12041)
                     /locus_tag="VYO11_000195"
     CDS             complement(11136..12041)
                     /locus_tag="VYO11_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HEV1594821.1"
                     /translation="MTAFQQLPSSVLQTGAIFLSIIIEALPFVLIGSIVSGLIEVYIT
                     PDKVYHFLPRNRWGRIFFGTFVGILFPSCECGIVPIINRFLEKKVPSYTAVPFLVTAP
                     VINPIVLFATYSAFGNSFHVALLRALGSILVAVILGIFLGFFWQEPIQKENRLACHEH
                     DFSYLSSAKKVFQVFVQAIDEFFDTGRYLVFGCLFASIIQVYVPTRILTSISATPLFA
                     ILLLMLLAFLLSLCSEADAFIGASLLSSFGLAPVLAFLVIGPMLDIKNILMMKNYLKA
                     RFISHFITIVTLVVLAYSLLIGVIL"
     gene            complement(12371..12454)
                     /locus_tag="VYO11_000196"
                     /pseudo
     CDS             complement(12371..12454)
                     /locus_tag="VYO11_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            12498..14627
                     /locus_tag="VYO11_000197"
     CDS             12498..14627
                     /locus_tag="VYO11_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HEV1594822.1"
                     /translation="MDKKYEKISQDLGVTLKQIDTVLSLTAEGATIPFIARYRKDMTG
                     SLDEVAIKAIIDLDKSLTNLNDRKEAVLAKIQEQGKLTKELEEAILVAEKLADVEELY
                     LPYKEKRRTKATIAREAGLFPLARLILQNIVDLEKEAEKFVCEGFATGKEALTGAVDI
                     LVEALSEDVTLRSMTYQEVLRHSKLTSQAKDESLDEKQVFQIYYDFSETVGTMQGYRT
                     LALNRGEKLGVLKIGFEHATDRILAFFATRFKVKNVYIDEVVQQSVKKKVLPAIERRI
                     RTELTEKAEEGAIQLFSDNLRNLLLVAPLKGRVVLGFDPAFRTGAKLAVVDATGKMLT
                     TQVIYPVKPASARQIEEAKKDLADLIGQYGVEIIAIGNGTASRESEAFVAEVLKDFPE
                     VSYVIVNESGASVYSASELARQEFPDLTVEKRSAISIARRLQDPLAELVKIDPKSIGV
                     GQYQHDVSQKKLSESLDFVVDTVVNQVGVNVNTASPALLSHVAGLNKTISENIVKYRE
                     EEGKITSRAQIKKVPRLGAKAFEQAAGFLRIPESSNILDNTGVHPENYTAVKELFKRL
                     DIKDLNEEAQSKLKSLSVKEMAQELDLGPETLKDIIADLLKPGRDFRDSFDAPVLRQD
                     VLDIKDLVVGQKLEGVVRNVVDFGAFVDIGIHEDGLIHISHMSRKFIKHPSQVVSVGD
                     LVTVWVKKIDTEREKVNLSLLAPNETD"
     gene            14614..15063
                     /locus_tag="VYO11_000198"
     CDS             14614..15063
                     /locus_tag="VYO11_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HEV1594823.1"
                     /translation="MKLTDYVKQVSLEDFGRAFIHHVQWNRRLRSTGGRFFPKDGHLD
                     FNPKVYQKLGMEVFRKIVRHELCHYHLYFQGKGYQHKDRDFKELLKAVDGLRFVPSLP
                     NSNSKPLKLYRCQSCQQRYQRKRRIDTKRYRCGLCRGKLLLINQPED"
     gene            15122..15394
                     /locus_tag="VYO11_000199"
     CDS             15122..15394
                     /locus_tag="VYO11_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HEV1594824.1"
                     /translation="MNSKFYKMRRNRMISGVLAGLSDKWNFDVTLVRFLFAIFTVANF
                     GLGVIIYIILASIMPTKEEIEAEMYGTGPRKRKEAQAIDDNEGWFW"
     gene            complement(15748..15939)
                     /locus_tag="VYO11_000200"
     CDS             complement(15748..15939)
                     /locus_tag="VYO11_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1594825.1"
                     /translation="MKHKEHILIGLLYLLSPFIGQLLVEHTHFIGTEFTGTAYVICWL
                     SVVISIHHFSKNILSQQQK"
     gene            16367..17125
                     /locus_tag="VYO11_000201"
     CDS             16367..17125
                     /locus_tag="VYO11_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1594826.1"
                     /translation="MTLLDVKHVQKIYKTRFQGNQVEALKDIHFTVEKGDYVAIMGES
                     GSGKSTLLNILAMLDKPSRGQVYLNGTDTATIKNSQASSFRREKLGFVFQDFNLLDTL
                     SVKDNILLPLVLSRRPITEMMKKLVVTAENLGINQLQEKYPYEISGGQKQRVAVARAI
                     ITEPEILLADEPTGALDSKSSAALLDVFDEINERGQTILMVTHSTAAASRAKRVLFIK
                     DGILYNQIYRGEKTERQMFQEISDTLTVMASEVN"
     gene            17127..19115
                     /locus_tag="VYO11_000202"
     CDS             17127..19115
                     /locus_tag="VYO11_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1594827.1"
                     /translation="MFRLTNKLAVSNLIKNRKLYYPFALAVLLAVTVTYLFYSLTFNP
                     KIAEIRGGTTIQATLGFGMFVVTLASAIIVLYANSFVMKNRSKELGIYGMLGLEKRHL
                     ISMTFKELVVFGILTVGAGIGIGALFDKLIFAFLLKLMKLKVELVATFQTKVVITVLV
                     VFGLIFLGLMFLNALRIARMNALQLSREKASGEKKGRFLPLQTILGSISLGIGYYLAL
                     TVKDPLTALTTFFIAVLLVIFGTYLLFNAGITVFLQILKKNKKYYYQPNNLISVSNLI
                     FRMKKNAVGLATIAILSTMVLVTMSAATSIFNSSESFKKVLNPHDFGVSGQNVEKEDL
                     DKLLSQFASDKGYKIKEKEVFRYTYFAVANQEGTELTIFEKGQNRVQPKTIFMVFDQK
                     DYENMTGQKLSLSGNEVGLFAKNEGVKEQKTLILNDHQFSVKEEFNKDFIVKHVPNQF
                     NILTADYNYLVVPDLQAFLNQFPDSAIYNQFYGGMNVNVSEEEQLKVAEEYEKYLQKF
                     NAQLNTEGNYVYGSTLADASAQMSVLFGGVFFIGIFLSIIFMVGTVLVIYYKQISEGY
                     EDRERFIILQKVGLDQKQIKQTINKQVLTVFFLPLLFAFLHLAFAYHMLSLILKVIGV
                     LDTTMMLIVTLSICAIFLIAYVLIFMITSRSYRKIVQM"
     gene            complement(19157..19801)
                     /locus_tag="VYO11_000203"
                     /pseudo
     CDS             complement(19157..19801)
                     /locus_tag="VYO11_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234620.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="VIT family protein"
     gene            complement(19827..20822)
                     /locus_tag="VYO11_000204"
                     /pseudo
     CDS             complement(19827..20822)
                     /locus_tag="VYO11_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153874.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            21529..23004
                     /locus_tag="VYO11_000205"
     CDS             21529..23004
                     /locus_tag="VYO11_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000661022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HEV1594828.1"
                     /translation="MKELDQNQAPIYEALVKLRKKRIVPFDVPGHKRGRGNPELVELL
                     GEKCVGIDVNSMKPLDNLGHPISIIRDAEELAADAFGASHAFLMIGGTTSSVQTMILA
                     TCKAGDKIILPRNVHKSAINALVLCGAIPIYIEMSVDPKIGIALGLENDRVAQAIKDH
                     PDAKATLINNPTYYGICSDLKGLTEMAHEAGMMVLVDEAHGAHLHFTGKLPISAMDAG
                     ADMAAVSMHKSGGSLTQSSLLLIGEQMSPEYVRQIINLTQSTSASYLLMASLDISRRN
                     LALRGKESFEEVIELSEYARHEINAIGGYYAYSKELIDGVSVCDFDVTKLSVYTQGIG
                     LTGIEVYDLLRDEYDIQIEFGDIGNILAYISIGDRIQDIERLVGALADIKRLYSRDGK
                     DLIAGEYIQPELVLSPQEAFYSERKSLTLDESVGQVCGEFVMCYPPGIPILAPGERIT
                     REIVDYIQFAKERGCSLQGTEDPEVNHINVIKRKTNYKKSQ"
     gene            complement(22970..23685)
                     /locus_tag="VYO11_000206"
                     /pseudo
     CDS             complement(22970..23685)
                     /locus_tag="VYO11_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809094.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            23941..24801
                     /gene="speE"
                     /locus_tag="VYO11_000207"
     CDS             23941..24801
                     /gene="speE"
                     /locus_tag="VYO11_000207"
                     /EC_number="2.5.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyamine aminopropyltransferase"
                     /protein_id="HEV1594829.1"
                     /translation="MDLWFSEVHTPDVKLSLRTAKQLYAGKSEWQDIEVLDTPAFGKI
                     LILNGHVLFSDADDFVYNEMTVHVPMAVHPNPKKVLVIGGGDGGVAQVLTLYPELEQI
                     DIVEPDEMLVEVCREYFPDFAAGLDDPRVTIYYQNGLRFLRNCEDDYDIIINDATDPF
                     GHTEGLFTKEFYGNSYRALKEDGIMIYQHGSPFFDEDESACRSMHRKVNQSFPISRVY
                     QAHIPTSPAGYWLFGFASKKYHPVKDFDKEGWKKRQLFTEYYTANLHVGSFMLPKYVE
                     DILEEEEGKK"
     gene            24798..26057
                     /locus_tag="VYO11_000208"
     CDS             24798..26057
                     /locus_tag="VYO11_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000088792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="saccharopine dehydrogenase family protein"
                     /protein_id="HEV1594830.1"
                     /translation="MSRLLVIGCGGVAQVAISKICQDSETFTEIMIASRTKSKCDDLK
                     AKLEGKTSTKIETAALDADKVEEVIALIESYKPEAVLNVALPYQDLTIMDACLATGVH
                     YIDTANYEAEDTEDPEWRAIYEKRCKELGFTAYFDYSWQWAYQEKFKEAGLTALLGSG
                     FDPGVTSVFSAYALKHYFDEIHYIDILDCNGGDHGYPFATNFNPEINLREVSAPGSYW
                     EDGKWVEVEAMSIKREYDFPQVGQKDMYLLHHEEIESLAKNIPGVKRIRFFMTFGQSY
                     LTHMKCLENVGLLRTDTINFNGQEIVPIQFLKALLPDPASLGPRTVGKTNIGCIFTGV
                     KDGVEKTIYIYNVCDHQECYAEVGSQAISYTTGVPAMIGTKLVMNGTWKQAGVYNLEE
                     LDPDPFMEALNEYGLPWVVVENPQMVD"
     gene            26057..27184
                     /gene="nspC"
                     /locus_tag="VYO11_000209"
     CDS             26057..27184
                     /gene="nspC"
                     /locus_tag="VYO11_000209"
                     /EC_number="4.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxynorspermidine decarboxylase"
                     /protein_id="HEV1594831.1"
                     /translation="MKLEQVPTPAYVIDLAKLEANCRILQYVQEEVGCKVLLAQKAYS
                     LYKTYPLISQYLSGTTASGLYEAKLAREEFPGEVHVFAPAFKDADLEELLGITDHIVF
                     NSERQLRKHGARCREAGVSVGLRLNPQCSTQGDHALYDPCAPGSRFGVTIDKIPSDLL
                     DLVDGLHFHTLCEQGADDLQTTLKAVEEQFGPYLHEVKWLNMGGGHHITREGYDVDLL
                     ISEIKRIRKTYNLEIYIEPGEAIALNAGYLATEVLDIVENGMEILVLDASATCHMPDV
                     LEMPYRPPLRNGFEAQEKAHTYRLSSNTCLTGDVIGDYSFENPVQIGDRLYFQDMAIY
                     SFVKNNTFNGIGLPSLYLMDEQGDCSLLKAFGYQDFKGRLS"
     gene            27181..28266
                     /gene="aguA"
                     /locus_tag="VYO11_000210"
     CDS             27181..28266
                     /gene="aguA"
                     /locus_tag="VYO11_000210"
                     /EC_number="3.5.3.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="agmatine deiminase"
                     /protein_id="HEV1594832.1"
                     /translation="MMDSPKKLGYHMPAEYEPHHGTLMIWPTRPGSWPFQGKAAKRAF
                     TQIIETIAEGERVYLLVEQAYLYEAQSYLGDKVVYLDIPTNDAWARDTGPTILVNDKG
                     KKLAVDWAFNAWGGTYDGLYQDYEEDDQVASRFAEVLEKPVYDAKPFVLEGGAIHSDG
                     QGTILVTESCLLSPGRNPNLTKEEIENTLLESLGAEKVIWLPYGIYQDETNEHVDNVA
                     AFVGSAELVLAWTDDENDPQYAMSKADLELLEQETDAKGCHFTIHKLPIPAVRQVVTE
                     EDLPGYIYEEGEEERYAGERLAASYVNFYIANKAVLVPQFEDVNDQVAIDILSKCFPD
                     RKVVGIPARDILLGGGNIHCITQQIPE"
     gene            28276..29151
                     /gene="aguB"
                     /locus_tag="VYO11_000211"
     CDS             28276..29151
                     /gene="aguB"
                     /locus_tag="VYO11_000211"
                     /EC_number="3.5.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001246759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-carbamoylputrescine amidase"
                     /protein_id="HEV1594833.1"
                     /translation="MRNVRVATIQMQCAKDVATNIQTAERLVRQAAEQGAQIILLPEL
                     FEHPYFCQERQYDYYQYAQSVAENTAIQHFKVIAKELQVVLPISFYEKDGNVLYNSIA
                     VIDADGEVLGVYRKTHIPDDHYYQEKFYFTPGNTGFKVWNTRYAKIGIGICWDQWFPE
                     TARCLALNGAELLFYPTAIGSEPILDTDSCGHWQRTMQGHAAANIVPVIAANRYGLEE
                     VTPSEENGGQSSSLDFYGSSFMTDETGAILERAERQEEAVLLATYDLDKGASERLNWG
                     LFRDRRPEMYRQITD"
     gene            complement(29332..30141)
                     /locus_tag="VYO11_000212"
     CDS             complement(29332..30141)
                     /locus_tag="VYO11_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000593565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV1594834.1"
                     /translation="MIKLLALDMDGTLLNEAKEIPQAHITAIHKAIEKGVKLVLCTGR
                     PLFGVLPYYKKLELDLQNEYIIVNNGCSTHQTSDWSLVDWKELSPADIEYLYDLAEKS
                     DVQLTLFDESHYFVLGGKPNQVIENDAKLVFSDLTEISLEEATSGKFRMFQGMFLGTK
                     EQTDDFEQRFAEELCQRFSGVRSQPVIYEAMPLGTTKATALSRLAEILKIDSSEIMAM
                     GDANNDIEMLQFAGLGIAMGNASDYVKSLADAVTSSNEEDGVARAIEKYTL"
     gene            30413..30634
                     /locus_tag="VYO11_000213"
     CDS             30413..30634
                     /locus_tag="VYO11_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000602450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0924 family bacteriocin-like peptide"
                     /protein_id="HEV1594835.1"
                     /translation="MILMTKNINLTNEELELIQGGADPYGKNPNGRYDWEIEPVLTLP
                     VHGFCPRGTYDLGYIGGGNHLCKGSAARF"
     gene            30688..31359
                     /locus_tag="VYO11_000214"
     CDS             30688..31359
                     /locus_tag="VYO11_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV1594836.1"
                     /translation="MKKRAIQILLALSLIFYKSTWFWRVFNHLAKPYLPASREFFQIL
                     LLMESGVLFLAVIYLLVFAGKKIFHFKWQLRYFIYLLLGYIISYMSDFLFSYFISLSS
                     NQISLNETVEMMGRQEFPYFLLIVCFIAPIAEELIYRGVLMTTFFKNSPWYGDVLLSA
                     IIFGYIHINFALTPLAFFIYASGGLILALLYRMTKNLYYPILVHILINITAFWDVWLL
                     LFSGS"
     gene            complement(31411..31608)
                     /locus_tag="VYO11_000215"
     CDS             complement(31411..31608)
                     /locus_tag="VYO11_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1594837.1"
                     /translation="MFIFYPQLLYLFIIPYFRSFPKRKKEHPILLNYLHYLPFSRQSY
                     FQNQFKKISGYTPLQYRKEKR"
     gene            31601..32509
                     /locus_tag="VYO11_000216"
     CDS             31601..32509
                     /locus_tag="VYO11_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001025716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEV1594838.1"
                     /translation="MNIQQLRYVVAIANSGTFREAAEKMYVSQPSLSISVRDLEKELG
                     FKIFRRTSSGTFLTRRGMEFYEKAQELVKGFDIFQNQYANPEEEKDEFSVASQHYDFL
                     PPTITAFSERYPDYKNFRIFESTTVQILDEVAQGHSEIGIIYLNNQNKKGIMQRVEKL
                     GLEVIELIPFHTHIYLCEGHPLAQKEELVMEDLADLPTVRFTQEKDEYLYYSENFVDT
                     SASSQMFNVTDRATLNGILERTDAYATGSGFLDSDSVNGITVIRLKDNLDNRMVYVKR
                     EEVELSQAGTLFVEVMQEYFDQKRKS"
     gene            32506..32967
                     /locus_tag="VYO11_000217"
     CDS             32506..32967
                     /locus_tag="VYO11_000217"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HEV1594839.1"
                     /translation="MKKRAIVAVIVLLLIGLDQLVKSYIVQQIPLGEVRSWIPNFVSL
                     TYLQNRGAAFSILQDQQLLFAVITLVVVIGAIWYLHKHMEDSFWMVLGLTLIIAGGLG
                     NFIDRVSQGFVVDMFHLDFINFAIFNVADSYLTVGVIILLIAMLKEEINGN"
     gene            32957..33844
                     /locus_tag="VYO11_000218"
     CDS             32957..33844
                     /locus_tag="VYO11_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEV1594840.1"
                     /translation="MEIKIETGGLRLDKALSDLSELSRSLANEQIKSGQVLVNGQVKK
                     AKYTVQEGDVVTYHVPEPEVLEYVAEDLPLEIVYQDEDVAVVNKPQGMVVHPSAGHTS
                     GTLVNALMYHIKDLSGINGVLRPGIVHRIDKDTSGLLMIAKNDDAHLALAQELKDKKS
                     LRKYWAIVHGNLPNDRGVIEAPIGRSEKDRKKQAVTAKGKPAVTRFHVLERFGDYSLV
                     ELQLETGRTHQIRVHMAYIGHSVAGDEVYGPRKTLKGHGQFLHAKTLGFTHPRTGKTL
                     EFKADIPEIFKETLERLRK"
     gene            33847..35730
                     /gene="cbpE"
                     /locus_tag="VYO11_000219"
                     /gene_synonym="pce"
     CDS             33847..35730
                     /gene="cbpE"
                     /locus_tag="VYO11_000219"
                     /gene_synonym="pce"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine esterase CbpE"
                     /protein_id="HEV1594841.1"
                     /translation="MKKKLTSLALVGAFLGLSWYGNVQAQESSGNKIHFINVQEGGSD
                     AIILESNGHFAMVDTGEDYDFPDGSDSRYPWREGIETSYKHVLTDRVFRRLKELGVQK
                     LDFILVTHTHSDHIGNVDELLSTYPVDRVYLKKYSDNRITNSERLWDNLYGYDKVLQT
                     ASEKGVSVIQNITQGDAHFQFGDMDIELYNYENETDSSGELKKIWDDNSNSLISVVKV
                     NGKKIYLGGDLDNVHGAEDKYGPLIGKVDLMKFNHHHDTNKSNTKDFIKNLSPSLIVQ
                     TSDSLPWKNGVDSEYVNWLKERGIERINAASKDYDATVFDIRQDGLVNISTSYKPIPS
                     FQAGWHKSSYGNWWYQAPDSTGEYAVGWNEIKGEWYYFNQTGILLQNQWKKWNNRWFY
                     LTDSGVAAKNWKKIAGIWYYFNKENQMEIGWIQDKEQWYYLDVDGSMKTGWLQYKGQW
                     YYFAPSGEMKTGWVKDKEAWYYMDSTGIMKTGEIEVAGHHYYLEESGAMKQGWLKKAN
                     DWYFYKTDGSRAIGWIKDKDKWYFLKENGQLLVNGKTPEGYTVDSSGAWLVDVPIEKS
                     ATIKTTSHSEIKESKEVVKKDLENKETSQHESVTNSSTSQDLTSSTSQSSETSVNKSE
                     SEQ"
     gene            35810..36940
                     /locus_tag="VYO11_000220"
     CDS             35810..36940
                     /locus_tag="VYO11_000220"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004240022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HEV1594842.1"
                     /translation="MNNRSETMKYKRIVFKVGTSSLTNEDGSLSRSKVKDITQQLAML
                     HEAGHELILVSSGAIAAGFGALGFKKRPTKIADKQASAAVGQGLLLEEYTTNLLLRQI
                     VSAQILLTQDDFVDKRRYKNAHQALSVLLNRGAIPIINENDSVVIDEVKVGDNDTLSA
                     QVAAMVQADLLVLLTDVDGLYTGNPNSDPRAKRLERIETINREIIDMAGGAGSSNGTG
                     GMLTKIKAATIATESGVPVYICSSLKSDSMIEAAEETEDGSYFVAQEKGLRTQKQWLA
                     FYAQSQGSIWVDKGAAEALSQHGKSLLLSGIVEAEGAFSYGDIVTVFDKESGKSLGKG
                     RVQFGASALEDILRSQKAKGVLIYRDDWISITPEIQLLFTEF"
     gene            36950..38212
                     /locus_tag="VYO11_000221"
     CDS             36950..38212
                     /locus_tag="VYO11_000221"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HEV1594843.1"
                     /translation="MVSRQEQFEQVQAVKKSINTASEEVKNQALLAMADHLVAATEEI
                     LAANALDMAAAKGKISDVMLDRLYLDADRIEAMARGIREVVALPDPIGEVLETSQLEN
                     GLVITKKRVAMGVIGIIYESRPNVTSDAAALTLKSGNAVVLRSGKDAYQTTHAIVTAL
                     KKGLETTTIHPNVIQLVEDTSHESSYAMMKAKGYLDLLIPRGGAGLINAVVENAIVPV
                     IETGTGIVHVYVDKDADEDKALSIINNAKTSRPSVCNAMEVLLVHEDKAASILPRLDQ
                     MLVAERKEAGLEPIQFRLDSKASQFVSGQAAETQDFDTEFLDYVLAVKVVSSLEEAVA
                     HIESHSTHHSDAIVTENAEAAAYFTDQVDSAAVYVNASTRFTDGGQFGLGCEMGISTQ
                     KLHARGPMGLKELTSYKYVVTGDGQIRE"
     gene            38216..39013
                     /gene="proC"
                     /locus_tag="VYO11_000222"
     CDS             38216..39013
                     /gene="proC"
                     /locus_tag="VYO11_000222"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HEV1594844.1"
                     /translation="MKIGFIGLGNMGASLAKSVLQARPSDEILLANRSQVKVDAFIAN
                     FGGQTSNNEEIFEEADVIFLGVKPAQFSELLSQYQTILEKRESLLLISMAAGLILEKL
                     ASLIPSQHRIIRMMPNTPASIGQGVISYALSPNCRAEDSELFCQLLSKAGLLVELGES
                     LINAATGLAGCGPAFVYLFIEALADAGVQTGLPRETALKMAAQTVVGAGQLVLESQQH
                     PGVLKDQVCSPGGSTIAGVASLEAHAFRGTVMEAVHQAYKRTQELGK"
     gene            39233..39871
                     /locus_tag="VYO11_000223"
     CDS             39233..39871
                     /locus_tag="VYO11_000223"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HEV1594845.1"
                     /translation="MSKGFLVSLEGPEGAGKTSVLEALLPILEVKGVKVLTTREPGGV
                     LIGEKIREVILDPSHTQMDAKTELLLYIASRRQHLVEKVLPALEAGKLVIMDRFIDSS
                     VAYQGFGRGLDIEAIDWLNQFATDGLKPDLTLYFDIEVEEGLARIAANSDREVNRLDL
                     EGLDLHKKVRQGYLSLLDKEGNRIVKIDASLPLEQVVETTNAVLFDGMGLAK"
     gene            39868..40758
                     /locus_tag="VYO11_000224"
     CDS             39868..40758
                     /locus_tag="VYO11_000224"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HEV1594846.1"
                     /translation="MKQDQLKAWQPAQFDRFVRILEQDQLNHAYLFSGFFGSLEMAQF
                     LAKSLFCTDKVGVLPCEKCRSCKLIEQEEFPDVTLIKPVNQVIKTERIRELVGQFSQA
                     GIESQQQVFIIEQADKMHPNAANSLLKVIEEPQSEVYIFFLTSDEEKMLPTIRSRTQI
                     FHFKKQEEKLILLLEQMGLVKKKATLLAKFSQSRAEAEKLAHQASFWTLVDESERLLT
                     WLVAKKKESYLQVAKLANLADDKEKQDQVLRILEVLCGQDLLQVRVRVILQDLLEARK
                     MWQANVSFQNAMEYLVLKEI"
     gene            40798..41115
                     /gene="yabA"
                     /locus_tag="VYO11_000225"
     CDS             40798..41115
                     /gene="yabA"
                     /locus_tag="VYO11_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HEV1594847.1"
                     /translation="MDKKELFDALDDFSQQLLVTLADVEAIKKNLKSLVEENTALRLE
                     NSKLRERLGEVEADAPVKAKHVRESVRRIYRDGFHVCNDFYGQRREQDEECMFCDELL
                     YRE"
     gene            41118..41996
                     /gene="rsmI"
                     /locus_tag="VYO11_000226"
     CDS             41118..41996
                     /gene="rsmI"
                     /locus_tag="VYO11_000226"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001166890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HEV1594848.1"
                     /translation="MQIQKSFKGQSPYGKLYLVATPIGNLDDMTFRAIQTLKEVDWIA
                     AEDTRNTGLLLKHFDISTKQISFHEHNAKEKIPDLIGFLKAGQSIAQVSDAGLPSISD
                     PGHDLVKAAIEEEIAVVTVPGASAGISALIASGLAPQPHIFYGFLPRKSGQQKQFFDS
                     KKDYPETQIFYESPHRVADTLENMLEVYGDRSVVLVRELTKIYEEYQRGTISELLESI
                     SETSLKGECLLIVEGASKGVEEKDEEDLFLEIQARIQQGMKKNQAIKEVAKIYQWNKS
                     QLYAAYHDWEENQEND"
     gene            42131..43465
                     /gene="trmFO"
                     /locus_tag="VYO11_000227"
     CDS             42131..43465
                     /gene="trmFO"
                     /locus_tag="VYO11_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate--tRNA-(uracil(54)-
                     C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO"
                     /protein_id="HEV1594849.1"
                     /translation="MSQSYINVIGAGLAGSEAAYQIAERGIPVKLYEMRGVKSTPQHK
                     TDNFAELVCSNSLRGDALTNAVGLLKEEMRRLGSVILESAEATRVPAGGALAVDRDGF
                     SQMVTEKVANHPLIEVVRDEITELPTDVITVIATGPLTSDALAEKIHALNDGDGFYFY
                     DAAAPIIDVNTIDMSKVYLKSRYDKGEAAYLNAPMTKQEFMDFHEALVNAEEAPLNSF
                     EKEKYFEGCMPIEVMAKRGIKTMLYGPMKPVGLEYPDDYTGPRDGEFKTPYAVVQLRQ
                     DNAAGSLYNIVGFQTHLKWGEQKRVFQMIPGLENAEFVRYGVMHRNSYMDSPNLLEQT
                     YRSKKQPNLFFAGQMTGVEGYVESAASGLVAGINAARLFKEESEVIFPETTAIGSLAH
                     YITHADSKHFQPMNVNFGIIKELEGERIRDKKARYEKIAERALADLEEFLTV"
     gene            43549..44286
                     /locus_tag="VYO11_000228"
     CDS             43549..44286
                     /locus_tag="VYO11_000228"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000013002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HEV1594850.1"
                     /translation="MANPKYKRILIKLSGEALAGERGVGIDIQTVQTIAKEIQEVHSL
                     GIEIALVIGGGNLWRGEPAAEAGMDRVQADYTGMLGTVMNALVMADSLQQVGVDTRVQ
                     TAIAMQQVAEPYVRGRALRHLEKGRIVIFGAGIGSPYFSTDTTAALRAAEIEADAILM
                     AKNGVDGVYNADPKKDKTAVKFEELTHRDVINKGLRIMDSTASTLSMDNDIDLVVFNM
                     NQSGNIKRVVFGENIGTTVSNNIEEKE"
     gene            44295..44852
                     /gene="frr"
                     /locus_tag="VYO11_000229"
     CDS             44295..44852
                     /gene="frr"
                     /locus_tag="VYO11_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HEV1594851.1"
                     /translation="MANVIIEKAKERMTQSHQSLAREFGGIRAGRANASLLDRVHVEY
                     YGVETPLNQIASITIPEARVLLVTPFDKSSLKDIERALNASDLGITPANDGSVIRLVI
                     PALTEETRRDLAKEVKKVGENAKVAVRNIRRDAMDEAKKQEKAKEITEDELKTLEKDI
                     QKVTDDAVKHIDDMTANKEKELLEV"
     gene            44912..45766
                     /gene="cvfB"
                     /locus_tag="VYO11_000230"
     CDS             44912..45766
                     /gene="cvfB"
                     /locus_tag="VYO11_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding virulence regulatory protein CvfB"
                     /protein_id="HEV1594852.1"
                     /translation="MNTNLASFIVGLIIDENDRFYFVQKDGQTYALAKEEGQHTVGDT
                     VKGFAYTDMKQKLRLTTLEVTATQDQFGWGRVTEVRKDLGVFVDTGLPDKEIVVSLDI
                     LPELKELWPKKGDQLYIRLEVDKKDRIWGLLAYQEDFQRLARPAYNNMQNQNWPAIVY
                     RLKLSGTFVYLPENNMLGFIHPSERYAEPRLGQVLDARVIGFREVDRTLNLSLKPRSF
                     EMLENDAQMILTYLESNGGFMTLNDKSSPDDIKATFGISKGQFKKALGGLMKAGKIKQ
                     DQFGTELI"
     gene            45775..45990
                     /locus_tag="VYO11_000231"
     CDS             45775..45990
                     /locus_tag="VYO11_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HEV1594853.1"
                     /translation="MRKSFYTWLMTERNPKSNSPKAILADLAFEESAFPKHTDDFDEV
                     SRFLEEHASFSFNLGDFDSIWQEYLEH"
     gene            46076..47080
                     /locus_tag="VYO11_000232"
     CDS             46076..47080
                     /locus_tag="VYO11_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000658165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HEV1594854.1"
                     /translation="MKEHSIDIQLSHPDDLFHLFGSNERHLRLMEEELDVVIHARTEI
                     VQVLGEESACEEARQVIQALMVLVNRGMTVGTPDVVTAISMVKNDEIDKFVALYEEEI
                     IKDNTGKPIRVKTLGQKLYVDSVKQHDVTFGIGPAGTGKTFLAVTLAVTALKRGQVKR
                     IILTRPAVEAGESLGFLPGDLKEKVDPYLRPVYDALYQILGKDQTTRLMEREIIEIAP
                     LAYMRGRTLDDAFVILDEAQNTTIMQMKMFLTRLGFHSKMIVNGDISQIDLPRNVKSG
                     LIDAQEKLKNIYQIDFVHFSAKDVVRHPVVAQIIRAYEPAPVKKEESEELESQPLSEG
                     "
     gene            47188..47757
                     /locus_tag="VYO11_000233"
     CDS             47188..47757
                     /locus_tag="VYO11_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1594855.1"
                     /translation="MESIFVKFAQYPSIETERLLLRPVTLDDAEAMFDYASDKGNTRY
                     TFPTNQSLEETKNNIAQFYLANPLGRWGIELKSNGQFIGTIDLHKIDSVLKKAAIGYI
                     INKKYWNQGLTTEANRAVIELAFEKIGMNKLTALHDKDNPASGKVMEKSGMRFSHAEP
                     YACMDQHEKDRIVTRVHYVLTKEDYFANK"
     gene            47825..48475
                     /locus_tag="VYO11_000234"
     CDS             47825..48475
                     /locus_tag="VYO11_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000387331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComEA family DNA-binding protein"
                     /protein_id="HEV1594856.1"
                     /translation="MEAIIEKIKEYKIIVICTGLGLLVGGFFLLKPAPQTPVKETNLQ
                     AEVAAVSKDLVSEKEVNKEEKEEPVEQDLITVDVKGAVKSPGIYDLPVGSRVNDAVQK
                     AGGLTEQADSKSLNLAQKVSDEALVYVPTKGEEAVSQQTGSGTASSISKEKKVNLNKA
                     SLEELKQVKGLGGKRAQDIIDHREANGKFKSVDELKKVSGIGGKTIEKLKDYVTVD"
     gene            48459..50699
                     /locus_tag="VYO11_000235"
     CDS             48459..50699
                     /locus_tag="VYO11_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HEV1594857.1"
                     /translation="MLQWIKNFSIPLIYLSFLLLWLYYAIFSASYLALLGFVFLLVCL
                     FIQFPWKSAGKVLIICGIFGFWFVFQNWQQSQASQNLADSVERVRILPDTIKVNGDSL
                     SFRGKSNGRAFQVYYKLQSEEEKEAFQALTDLHEIGLEGKLSEPEGQRNFGGFNYQAY
                     LKTQGIYQTLNIKTIQSLQKIGSWDIGENLSSLRRKAVVWIKTHFPDPMRNYMTGLLL
                     GHLDTDFEEMNELYSSLGIIHLFALSGMQVGFFMNGFKKLLLRLGLTQEKLKWLTYPF
                     SLIYAGLTGFSASVIRSLLQKLLAQHGVKGLDNFALTVLVLFIVMPNFFLTAGGVLSC
                     AYAFILTMTSKEGEGLKAVTSESLVISLGILPILSFYFAEFQPWSILLTFVFSFLFDL
                     TFLPLLSILFVLSFLYPVIQLNFIFEWLEGIIRLVSQVTSRPLVFGQPNAWFLILLLI
                     SLALVYDLRKNIKKLTVLCLLITGLFLLTKHPLENEITMLDVGQGESIFLRDVTGKTI
                     LIDVGGKAESYKKIEKWQEKMTTSNAQRTLIPYLKSRGVAKIDQLILTNTDKENVGDL
                     SEVTKAFHVGEILVSKDSLKQKEFVAELQTTQTKVRSMTVGENLPIFGSQLEVLSPRK
                     MGDGGHDDTLVLYGKFLDKQFLFTENLEEKGEKDLLKHYPDLKVNVLKASQHGNKKSS
                     SPAFLEKLKPELTLISVGKSNRMKLPHQETLTRLEGINSKVYRTDQQGAIRFKGLDSW
                     KIESVR"
     gene            50878..51066
                     /locus_tag="VYO11_000236"
     CDS             50878..51066
                     /locus_tag="VYO11_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1594858.1"
                     /translation="MTATKSYKYDWNTVLEYSTNYHDHQYAWIPEWSRYYSYSEYKVG
                     GGWNYARYEVINYYTGGY"
     gene            51098..51685
                     /locus_tag="VYO11_000237"
     CDS             51098..51685
                     /locus_tag="VYO11_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000939891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1594859.1"
                     /translation="MLNLTHVTLKTRQVILQDADFTFKKGRIYGLLAINGSGKTTLFR
                     AMSKLLPLSSGHIAVPPSLFYYESVEWLDGNLSGMDYLRLIKNIWKSDLNLRDEIAYW
                     EMADYISLPIRKYSLGMKQRLVIAMYFLSQAKCWLMDEITNGLDEYYRQKFFDRLAQI
                     DRQEQLVLLSSHYKEELVDICDRVVTIHQGQIEEV"
     gene            51689..52870
                     /locus_tag="VYO11_000238"
     CDS             51689..52870
                     /locus_tag="VYO11_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1594860.1"
                     /translation="MKDVSLFLLKKVFKSRLNWIILLLFASVLGVTFYLNSQTANSHS
                     LESRLESRIAANERAINENEEKLSQMSDTSSEEYQFAKNNLDVQKNLLTRKTEILTLL
                     KEGRWKEAYYLQWQDEEKNYEFVSNDPTASSGLKMGVDRERKIYQALYPLNIKAHTLE
                     FPTHGIDQIVWILEVIIPSLFVVAIIFMLTQLFAERYQNHLDTAHLYPVSKVTFAISS
                     LGVGVGYVTVLFIGICGFSFLVGSLISGFGQLDYPYPIYSLVNQEVTIGKIQDVLFPG
                     LLLAFLAFIVIVEVVYLIAYFFKQKMPVLFLSLIGIVGLLFGIQTIQPLQRIAHLIPF
                     TYLRSVEILSGRLPKQIDNVNLNWSMGMVLLPCLIILLLVGILFIESWGSSRKKEVFK
                     V"
     misc_feature    53030..53161
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            53177..53707
                     /gene="infC"
                     /locus_tag="VYO11_000239"
     CDS             53177..53707
                     /gene="infC"
                     /locus_tag="VYO11_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000848185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HEV1594861.1"
                     /translation="MKTIAKQDLFINDEIRVREVRLIGLEGEQLGIKPLSEAQALADN
                     ANVDLVLIQPQAKPPVAKIMDYGKFKFEYQKKQKEQRKKQSVVTVKEVRLSPTIDKGD
                     FDTKLRNARKFLEKGNKVKVSIRFKGRMITHKEIGAKVLAEFAEATQDIAIIEQRAKM
                     DGRQMFMQLAPATDKK"
     gene            53740..53940
                     /gene="rpmI"
                     /locus_tag="VYO11_000240"
     CDS             53740..53940
                     /gene="rpmI"
                     /locus_tag="VYO11_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HEV1594862.1"
                     /translation="MPKQKTHRASAKRFKRTGSGGLKRFRAYTSHRFHGKTKKQRRHL
                     RKASMVHSGDYKRIKAMLTRLK"
     gene            53992..54351
                     /gene="rplT"
                     /locus_tag="VYO11_000241"
     CDS             53992..54351
                     /gene="rplT"
                     /locus_tag="VYO11_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019786714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HEV1594863.1"
                     /translation="MARVKGGVVSRKRRKRILKLAKGYYGAKHILFRTAKEQVMNSYY
                     YAYRDRRQKKRDFRKLWITRINAAARMNGLSYSQLMHGLKLAEIEVNRKMLADLAVND
                     AVAFTALADAAKAKLGK"
     gene            54409..54789
                     /locus_tag="VYO11_000242"
     CDS             54409..54789
                     /locus_tag="VYO11_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEV1594864.1"
                     /translation="MASKMLHTCLRVENLEKSIAFYQDAFGFKELRRRDFPDHAFTIV
                     YLGLEGDDYELELTYNYDHGPYVVGDGFAHIALSTPDLEALHQEHSAKGYEVTEPNGL
                     PGTTPNYYFVKDPDGYKVEVIREK"
     gene            55039..55839
                     /locus_tag="VYO11_000243"
     CDS             55039..55839
                     /locus_tag="VYO11_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HEV1594865.1"
                     /translation="MNLTCKKRLGVIRLETMKVVAQEEIAPAIFELVLEGEMVEAMRA
                     GQFLHLRVPDDAHLLRRPISISSIDKANKQCHLIYRIEGAGTAIFSTLSQGDTLDVMG
                     PQGNGFDLSDLDEQNQVLLVGGGIGVPPLLEVAKELHERGVKVVTVLGFANKDAVILK
                     TELAQYGQVFVTTDDGSYGIKGNVSVVINDLDSQFDAVYSCGAPGMMKYINQTFDDHP
                     RAYLSLESRMACGMGACYACVLKVPESETVSQRVCEDGPVFRTGTVVL"
     gene            55802..56788
                     /locus_tag="VYO11_000244"
     CDS             55802..56788
                     /locus_tag="VYO11_000244"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013193458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HEV1594866.1"
                     /translation="MVLFSAQEQLYYKEKIMTTNRLQVSLPGLDLKNPIIPASGCFGF
                     GQEYAKYYDLNLLGSIMIKATTLEPRFGNPTPRVAETPAGMLNAIGLQNPGLEVVLAE
                     KLPWLEREYPNLPIIANVAGFSKQEYAAVSHGISKATNVKAIELNISCPNVDHCNHGL
                     LIGQDPDLAYDVVKAAVEASEVPVYVKLTPSVTDIVTVAKAAEDAGASGLTMINTLVG
                     MRFDLKTRKPILANGTGGMSGPAVFPVALKLIRQVAQTTDLPIIGMGGVDSAEAALEM
                     YLAGASAIGVGTANFTNPYACPDIIENLPKVMDKYGISSLEELRQEVKESLR"
     gene            56830..58995
                     /gene="lytB"
                     /locus_tag="VYO11_000245"
     CDS             56830..58995
                     /gene="lytB"
                     /locus_tag="VYO11_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endo-beta-N-acetylglucosaminidase"
                     /protein_id="HEV1594867.1"
                     /translation="MNLGEFWYNKINKNRGRRLMKKVRFIFLALLFFLASPEGAMASD
                     GTWQGKQYLKEDGSQAANEWIFDTHYQSWFYIKADANYAENEWLKQGDDYFYLKSGGY
                     MAKSEWVEDKGAFYYLDQDGKMKRNAWVGTSYVGATGAKVIEDWIYDSQYDAWFYIKA
                     DGQHAEKEWLQIKGKDYYFKSGGYLLTSQWINQAYVNASGAKVQQGWLFDKQYQSWFY
                     IKENGNYADKEWIFENGHYYYLKSGGYMAANEWIWDKESWFYLKFDGKIAEKEWVYDS
                     HSQAWYYFKSGGYMAANEWIWDKESWFYLKFDGKMAEKEWVYDSHSQAWYYFKSGGYM
                     TANEWIWDKESWFYLKSDGKIAEKEWVYDSHSQAWYYFKSGGYMTANEWIWDKESWFY
                     LKSDGKMAEKEWVYDSHSQAWYYFKSGGYMAKNETVDGYQLGSDGKWLGGKATNKNAA
                     YYQVVPVTANVYDSDGEKLSYISQGSVVWLDKDRKSDDKRLAITISGLSGYMKTEDLQ
                     ALDASKDFIPYYESDGHRFYHYVAQNASIPVASHLSDMEVGKKYYSADGLYFDGFKLE
                     NPFLFKDLTEATNYSAEELDKVFSLLNINNSLLENKGATFKEAEEHYHINALYLLAHS
                     ALESNWGRSKIAKDKNNFFGITAYDTTPYLSAKTFDDVDKGILGATKWIKENYIDRGR
                     TFLGNKASGMNVEYASDPYWGEKIASVMMKINEKLGGKD"
     gene            complement(59056..60711)
                     /gene="pavA"
                     /locus_tag="VYO11_000246"
     CDS             complement(59056..60711)
                     /gene="pavA"
                     /locus_tag="VYO11_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_094859469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rqc2 family fibronectin-binding protein PavA"
                     /protein_id="HEV1594868.1"
                     /translation="MSFDGFFLHHIVEELRSELVNGRIQKINQPFEQELVLQIRSNRQ
                     SHRLLLSAHPVFGRIQLTQTTFENPAQPSTFIMVLRKYLQGALIESIEQVENDRIVEI
                     TVSNKNEIGDHIQATLIIEIMGKHSNILLVDKSSHKILEVIKHVGFSQNSYRTLLPGS
                     TYIAPPSTESLNPFTIKDEKLFEILQTQELTAKNLQSLFQGLGRDTANELERILVSEK
                     LSAFRNFFNQETKPCLTETSFSPVPFANQVGEPFANLSDLLDTYYKDKAERDRVKQQA
                     SELIRRVENELQKNRHKLKKQEKELLATDNAEEFRQKGELLTTFLHQVPNDQDQVILD
                     NYYTNQPIMIALDKALTPNQNAQRYFKRYQKLKEAVKYLTDLIEETKATILYLESVET
                     VLNQAGLEEIAEIREELIQTGFIRRRQREKIQKRKKLEQYLASDGKTIIYVGRNNLQN
                     EELTFKMARKEELWFHAKDIPGSHVVISGNLDPSDAVKTDAAELAAYFSQGRLSNLVQ
                     VDMIEVKKLNKPTGGKPGFVTYTGQKTLRVTPDSKKIASMKKS"
     gene            60816..61313
                     /gene="ybeY"
                     /locus_tag="VYO11_000247"
     CDS             60816..61313
                     /gene="ybeY"
                     /locus_tag="VYO11_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HEV1594869.1"
                     /translation="MYIEMVDETGQVSKEMLQQTQEILEFAAQKLGKEDKEMAVTFVT
                     NERSHELNLEYRDTDRPTDVISLEYKPELEIAFDEEDLLENPELAEMMSEFDAYIGEL
                     FISIDKAHEQAEEYGHSFEREMGFLAVHGFLHINGYDHYTPEEEAEMFGLQEEILTAY
                     GLTRQ"
     gene            61294..61689
                     /locus_tag="VYO11_000248"
     CDS             61294..61689
                     /locus_tag="VYO11_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000378166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HEV1594870.1"
                     /translation="MDSQDNKRKWKNRDLISSLEFAITGIFTAIKEERNMRKHAVTAL
                     VVILAGFVFQVSRIEWLFLLLSIFLVVAFEIINSAIENVVDLASHYHFSMLAKNAKDM
                     AAGAVLVVSLFAALTGALIFLPRIWDLLF"
     gene            61706..62605
                     /gene="era"
                     /locus_tag="VYO11_000249"
     CDS             61706..62605
                     /gene="era"
                     /locus_tag="VYO11_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HEV1594871.1"
                     /translation="MTFKSGFVAILGRPNVGKSTFLNHVMGQKIAIMSDKAQTTRNKI
                     MGIYTTDKEQIVFIDTPGIHKPKTALGDFMVESAYSTLREVDTVLFMVPADEARGKGD
                     DMIIERLKAAKVPVILVVNKIDKVHPDQLLSQIDDFRNQMDFKEIVPISALQGNNVSR
                     LVDILSENLDEGFQYFPSDQITDHPERFLVSEMVREKVLHLTREEIPHSVAVVVDSMK
                     RDEETDKVHIRATIMVERDSQKGIIIGKGGAMLKKIGSMARRDIELMLGDKVFLETWV
                     KVKKNWRDKKLDLADFGYNEKEY"
     gene            62653..63477
                     /gene="mutM"
                     /locus_tag="VYO11_000250"
     CDS             62653..63477
                     /gene="mutM"
                     /locus_tag="VYO11_000250"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001114577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HEV1594872.1"
                     /translation="MPELPEVETVCRGLEKLIIGKKISSIEIRYPKMIKTDLEEFQRE
                     LPSQIIESMGRRGKYLLFYLTDKVLISHLRMEGKYFYYPDQGPERKHAHVFFHFEDGG
                     TLVYEDVRKFGTMELLVPDLLDAYFISKKLGPEPSEQDFDLQVFQSALAKSKKPIKSH
                     LLDQTLVAGLGNIYVDEVLWRAQVHPARSSQTLTAEEATAIHDQTIAVLSQAVEKGGS
                     TIRTYTNAFGEDGSMQDFHQVYDKTGQECVRCGTIIEKIQLGGRGTHFCPNCQRRD"
     gene            63477..64082
                     /locus_tag="VYO11_000251"
     CDS             63477..64082
                     /locus_tag="VYO11_000251"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HEV1594873.1"
                     /translation="MRKIIGITGGIASGKSTVTNFLRQQGFQVVDADAVVHQLQKPGG
                     RLFEALVQHFGQEIILENGELNRPLLASLIFSNPEEQKWSKQIQGEIIREELATLREQ
                     LAQTEEIFFMDIPLLFEQDYSDWFAETWLVYVDRDAQVERLMKRDQLSKDEAESRLAA
                     QWPLEKKKDLASQVLDNNGNQNQLLNQVHILLEGGRQDDRD"
     gene            64069..65268
                     /locus_tag="VYO11_000252"
     CDS             64069..65268
                     /locus_tag="VYO11_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HEV1594874.1"
                     /translation="MTEINWKDNLRIAWFGNFLTGASISLVVPFMPIFVENLGVGSQQ
                     VAFYAGLAISVSAISAALFSPIWGILADKYGRKPMMIRAGLAMTITMGGLAFVPNIYW
                     LIFLRLLNGVFAGFVPNATALIASQVPKEKSGSALGTLSTGVVAGTLTGPFIGGFIAE
                     LFGIRTVFLLVGSFLFLAAILTICFIKEDFQPVAKEKAIPTKELFTSVKYPYLLLNLF
                     LTSFVIQFSAQSIGPILALYVRDLGQTENLLFVSGLIVSSMGFSSIMSAGVMGKLGDK
                     VGNHRLLVVAQFYSVIIYLLCANASSPLQLGLYRFLFGLGTGALIPGVNALLSKMTPK
                     AGISRVFAFNQVFFYLGGVVGPMAGSAVAGQFGYHAVFYATSLCVAFSCLFNLIQFRT
                     LLKVKEI"
     gene            65268..65417
                     /gene="rpmG"
                     /locus_tag="VYO11_000253"
     CDS             65268..65417
                     /gene="rpmG"
                     /locus_tag="VYO11_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEV1594875.1"
                     /translation="MRVKINLKCSSCDSINYLTSKNSKTHPDKIEVLKYCPKERKVTL
                     HLESK"
     gene            65457..65690
                     /gene="secG"
                     /locus_tag="VYO11_000254"
     CDS             65457..65690
                     /gene="secG"
                     /locus_tag="VYO11_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HEV1594876.1"
                     /translation="MYNLLLTILLVLSVVIVIAIFMQPTKNQSSNVFDASSGDLFERS
                     KARGFEAVMQRLTGILVFFWLAIALALTVLSSR"
     gene            65792..68146
                     /gene="rnr"
                     /locus_tag="VYO11_000255"
     CDS             65792..68146
                     /gene="rnr"
                     /locus_tag="VYO11_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HEV1594877.1"
                     /translation="MKDRIKEYLQDKGKVTVNDLAQALGKDSSKDFRELIKTLSLMER
                     KHQIRFEEDGSLTLEAKKKHEITLKGIFHAHKNGFGFVSLEGEEDDLFVGKNDVNYAI
                     DGDTVEVVIKKVADRNKGTAAEAKIIDILEHSLTTVVGQIVLDQEKPKYAGYIRSKNQ
                     KISQPIYVKKPALKLEGTEVLKVFIDKYPSKKHDFFVASVLDVVGHSTDVGIDVLEVL
                     ESMDIVSEFPEAVVKEAESVPDAPSQKDMEGRLDLRDEITFTIDGADAKDLDDAVHIK
                     ALKNGNLELGVHIADVSYYVTEGSALDKEALNRATSVYVTDRVVPMLPERLSNGICSL
                     NPQVDRLTQSAIMEIDKHGRVVNYTITQTVIKTSFRMTYSDVNDILAGDEEKRKKYHK
                     IVPSIELMAKLHETLENMRVKRGALNFDTNEAKILVDKQGKPVDIVLRQRGIAERIIE
                     SFMLMANETVAEHFSKLDLPFIYRIHEEPKAEKVQKFIDYASSFGLCIYGTASEISQE
                     ALQDIMRAVEGEPYADVLSMMLLRSMQQARYSEHNHGHYGLAADYYTHFTSPIRRYPD
                     LLVHRMIRDYGCSKEIAEHFEQVIPEIATQSSNRERRAIEAEREVEAMKKAEYMEEYV
                     GEEYDAVVSSIVKFGLFVELPNTVEGLIHITNLPEFYHFNERDLTLRGEKSGITFRVG
                     QQIRIRVERADKMTGEIDFSFVPSEFDVIEKGLKQSSRSGRGRGSNRRSDKKEDKRKL
                     GRSNDKRKHSQKDKKKKGKKPFYKEVAKKGAKHGKGRGKGRRTK"
     gene            68109..68576
                     /gene="smpB"
                     /locus_tag="VYO11_000256"
     CDS             68109..68576
                     /gene="smpB"
                     /locus_tag="VYO11_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HEV1594878.1"
                     /translation="MAKGEGKVVAQNKKARHDYTIVDTLEAGMVLTGTEIKSVRAARI
                     NLKDGFAQVKNGEVWLSNVHIAPYEEGNIWNQEPERRRKLLLHKKQIQKLEQETKGTG
                     MTLVPLKVYIKDGYAKLLLGLAKGKHDYDKRESIKRREQNRDIARVMKAVNQR"
     gene            68592..69452
                     /gene="tehB"
                     /locus_tag="VYO11_000257"
                     /pseudo
     CDS             68592..69452
                     /gene="tehB"
                     /locus_tag="VYO11_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413836.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase TehB"
     gene            69525..70478
                     /gene="coiA"
                     /locus_tag="VYO11_000258"
     CDS             69525..70478
                     /gene="coiA"
                     /locus_tag="VYO11_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000495911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HEV1594879.1"
                     /translation="MFVARDARGELVNVLEDKLEKQAYTCPACGGQLHLRQGPSVRTH
                     FAHKSLKDCDFFFENESPEHLANKESLYHWLKKETKVQLEYPLSELKQIADVFVNGNL
                     ALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
                     YVWELDKEKQVLRLKYLIYQDLRGKLHYQIKEFSYGQGSLLEILRLPYKRQKISHFTV
                     SEDKDICRYIRQQLYYQNLFWMKEQAEAYQKGENILTYGLKEWYPQIRPIVGKFFQIE
                     QDLTSYYQYFYTYYQKNPQNDWQKLYPPAFYQQYFLKNMVE"
     gene            70497..72299
                     /gene="pepF"
                     /locus_tag="VYO11_000259"
     CDS             70497..72299
                     /gene="pepF"
                     /locus_tag="VYO11_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HEV1594880.1"
                     /translation="MVLQRNEINEKDTWDLSTIYPTDQAWEEALKDLTEQLETVAQYE
                     GHLLDSADNLLEITEFSLEMERQMEKLYVYAHMKNDQDTREAKYQEYYAKAMTLYSQL
                     DQAFSFYDPEFMEISEKQYADFLEAQPKLQVYQHYFDKLLQGKDHVLSQREEELLAGA
                     GEIFGSASETFAILDNADIVFPYVLDDDGKEVQLSHGTYTRLMESKKREVRRGAYQAL
                     YATYEQFQHTYAKTLQTNVKVQNYRAKVRNYKSARHAALAANFVPESVYDNLVAAVRK
                     HLPLLHRYLELRSKILGISDLKMYDVYTPLSSVEYNFTYQEALKKAEDALAVLGEDYL
                     SRVKRAFSERWIDVYENQGKRSGAYSGGSYDTNAFMLLNWQDNLDNLFTLVHETGHSM
                     HSSYTRETQPYVYGDYSIFLAEIASTTNENILTEKLLEEVEDDATRFAILNNFLDGFR
                     GTVFRQTQFAEFEHAIHQADQNGEVLTSDFLNKLYADLNQEYYGLSKEDNPEIQYEWA
                     RIPHFYYNYYVYQYSTGFAAASALAEKIVHGSQEDRDRYIDYLKAGKSDYPLNVMRKA
                     GVDMEKEDYLNDAFAVFERRLNEFEALVEKIGLA"
     gene            72301..73014
                     /locus_tag="VYO11_000260"
     CDS             72301..73014
                     /locus_tag="VYO11_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HEV1594881.1"
                     /translation="MVESYSKNANHNMRRPVVKEEIVDLMRQRQKQVTGSLKELEDFA
                     RKENIPIIPHETVAYFRFLMETMQPKNILEIGTAIGFSALLMAEHAPNAKITTIDRNP
                     EMIGFAKENFAQFDSRKQITLLEGDAVDVLSTLTESYDFVFMDSAKSKYIVFLPEILK
                     HLEVGGVVVLDDIFQGGDVAKDIMEVRRGQRTIYRGLQKLFDATLDNPELTATLVPLG
                     DGILMLRKNVADVQLSESE"
     gene            73081..74022
                     /gene="prsA"
                     /locus_tag="VYO11_000261"
     CDS             73081..74022
                     /gene="prsA"
                     /locus_tag="VYO11_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase PrsA"
                     /protein_id="HEV1594882.1"
                     /translation="MKKKLLAGAITLLSVATLAACSKGSEGADLISMKGDVITEHQFY
                     EQVKSNPSAQQVLLNMTIQKVFEKQYGSELDDKEVDDTIAEEKKQYGENYQRVLSQAG
                     MTLETRKAQIRTSKLVELAVKKVAEAELTDEAYKKAFDEYTPDVTAQIIRLNNEDKAK
                     EVLEKAKAEGADFAQLAKDNSTDEKTKENGGEITFDSASTEVPEQVKKAAFALDVDGV
                     SDVITATGTQAYSSQYYIVKLTKKTEKSSNIDDYKEKLKTVILTQKQNDSTFVQSIIG
                     KELQAANIKVKDQAFQNIFTQYIGGGDSSSSSSTSNE"
     gene            complement(74141..>74480)
                     /locus_tag="VYO11_000262"
     CDS             complement(74141..>74480)
                     /locus_tag="VYO11_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HEV1594883.1"
                     /translation="VGTAFKEKHYENTILHSDQGWQYQHDSYHRFLESKGIQASMSRK
                     GNSQDNGRMESFFGILKSEMFYGYEQTFKSLNQLEQAIIDYIDYYNNKRIKIKLKGLS
                     SVQYRTKSFG"
BASE COUNT        22352 a        13696 c        16631 g        21801 t
ORIGIN      
        1 tagaaaataa attagtaagc tgatgaaatt tttctcaaga gaagctattt ataggtgaaa
       61 atggtataat atagtgagaa ggatagagga gaagtgtaaa ttgatcgcac aactagatac
      121 aaaaacagtc tatagtttta tggaaagcgt catttcgatc gaaaagtatg tgagagcagc
      181 taaagaatac ggctacactc atttggctat gatggatatt gacaatcttt atggcgcttt
      241 cgactttcta gagattacaa aaaaatacgg cattcatcct ttgctagggc ttgaaatgac
      301 agtgtttgta gatgatcagg aagtgaattt gcgcttttta gctctatcta gtgtgggcta
      361 tcagcagttg atgaagcttt cgacagccaa gatgcagggg gagaaaactt ggtcagtcct
      421 gtcccagtac ctggaggata tcgcggtcat tgtgccttat tttgatagag ttgagtcgtt
      481 agaactaggc tgtgattact atataggggt ttatccagaa acactagcaa gcgaatttca
      541 tcatcctatc ttacctcttt atcgggtcaa cgcttttgaa agcagggata gagaagttct
      601 tcaagtttta acagcgatta aagaaaatct accgctcaga gaagttccct tgcgttcgag
      661 acaagatgtc tttatatcag caagttcttt agagaaacta ttccaagagc gttttccgca
      721 agctttggac aatttagaaa agcttatttc aggcatttct tacgacttgg atactagtct
      781 gaaactgcct cgttttaatc cagctagacc agcagtagag gagttgagag agcgtgctga
      841 actggggctt gttcagaagg ggttgactag taaagaatat caagatagac tagaccaaga
      901 attgtctgtt attcatgata tgggctttga tgattatttc ttggttgttt gggatttgtt
      961 gcgttttgga cgatcgaatg gctattatat gggaatggga aggggttctg cagtaggcag
     1021 tttggtttct tatgccttag acatcacggg gattgaccca gtagagaaaa atctgatttt
     1081 tgaacgcttt cttaatcgtg aacgctatac catgcctgat attgatattg atatcccaga
     1141 tatttatcgt ccagatttta tcagatatgt tggtaataaa tatggtagta aacatgcggc
     1201 acaaatcgtt actttttcaa cctttggagc caagcaagct cttcgagatg tcttgaaacg
     1261 ctttggtgtg ccagagtatg aattatctgc aattactaag aaaatcagtt ttcgtgacaa
     1321 tcttaagtcg gcctatgagg gcaatctcca gtttcgtcag caaatcaata gtaagttaga
     1381 ataccaaaaa gcttttgaga ttgcttgcaa gatagagggc tatccaaggc aaacctctgt
     1441 ccatgcggct ggtgttgtaa ttagtgacca agatttgacc aactacattc ctctaaagta
     1501 tggtgatgaa attccactga ctcagtatga tgctcatgga gttgaggcta gcggactttt
     1561 gaagatggac tttctgggac tacgaaattt gacctttgtc cagaagatgc aagagttgct
     1621 tgttgaaaca gaaggtattc accttaaaat tgaagaaata gatttggaag acaaagaaac
     1681 gttagattta tttgcctctg gaaatacaaa aggtatcttt caatttgagc aacctggtgc
     1741 tattcgcttg ctcaaacgtg ttcaaccagt ctgttttgaa gatgtcgtag caactacttc
     1801 tctaaatcga ccaggtgcaa gtgactacat caataatttt gtggcaagga agcatgggca
     1861 ggaagaagtg actgttctag attcagctct ggaggatatt ttggctccaa cttatggcat
     1921 tatgctctat caggagcagg ttatgcaggt tgctcagcga tttgctggat ttagtcttgg
     1981 gaaggccgat attttgcgtc gagctatggg taaaaaggat gcctctgcta tgcatgagat
     2041 gagggcttcc tttattcaag gctccataga agcaggccat actgcggaaa aagcagggca
     2101 ggtttttgat gttatggaga agtttgcagg ctatggtttt aacaggtcac acgcctatgc
     2161 ctactcagca ttggccttcc agttggctta ttttaaaaca cattatccag ccatatttta
     2221 tcagattatg ttgaattctg ccaacagtga ttatgtaaca gatgccttag aagcaggttt
     2281 tgaagtagcc ccattgtcca tcaatactat tccctatcac gataaaattg ccaacaagtc
     2341 tatctatata ggtttgaaat cgattaaggg gctcagcaag gacttggcgc tttggattat
     2401 tgaacataga ccttattcta atattgaaga ttttatagct aaattacctg agaattatct
     2461 gaaacatcct ctgctagaac ctttggtaaa agttggcctt tttgatttat ttgaaaaaaa
     2521 tcgtcaaaaa gtatttaata acttagctaa tctatttgaa tttgtgaaag agttgggaag
     2581 tttgtttgga gatgctattt atagttggca ggaatcggaa gattggacgg aacaagaaaa
     2641 attttatatg gaacaagagc ttttagggat aggtgtcagc aaacatccac tacaagctat
     2701 tgcaagtaag gctatttacc cgattacccc aatcggaaat ttgtcagaaa atagctatgc
     2761 tattattttg gttgaagttc ggaaaataaa agtgattcgt accaaaaagg gtgaaaatat
     2821 ggccttctta caggcagatg atagtaagaa aaaattggat gtcactctct tttcagactt
     2881 atatcgtcag gttggacagg aaataaaaga gggagccttc tactatgtaa aaggaaaaat
     2941 acaatcacgt gatggccgtc tgcaaatgat tgcacaaaaa ataagagaag cagttgctga
     3001 acgcttttgg attcaggtta aaaatcatga ctcggagcaa gagatgtcac gtattttaga
     3061 ccagtataaa ggcccaatcc cagtcatcat ccggtatgaa gaggaacaga aaaccatcgt
     3121 ttctccccat cattttgtag ctaaatctga tgaattagag gcgaaattga atggaatagt
     3181 tatgaaaacg atttatcgct aaaattacgg aaaatagaag aattttcaac gtaaatgtgg
     3241 tataatcagt aagaatgtta aaagaaaaag gagcataacc aatatgaaac gtattgctgt
     3301 tttgactagt ggtggagacg cccctggtat gaacgctgcc atccgtgcag ttgttcgtca
     3361 agcaatttca gaaggaatgg aagtttttgg tatctatgac ggatatgctg gtatggttgc
     3421 cggtgaaatt catcccctag atgtagcttc agtaggggac atcatttctc gtggtggtac
     3481 tttccttcac tcagctcgtt acccagagtt cgctcaactt gaagggcaac ttaaagggat
     3541 tgagcaattg aaaaaacacg gaattgaagg tgtagttgtt atcggtggtg acggatctta
     3601 ccacggcgct atgcgtttga ctgaacatgg cttcccagct attggtcttc caggtacaat
     3661 cgataacgat atcgttggta ctgactttac aatcggtttt gacacagcgg ttactactgc
     3721 catggacgct attgataaga ttcgtgatac atcatcaagt caccgtcgta cttttgtaat
     3781 cgaagttatg ggacgtaacg ctggtgatat cgctctttgg gctggtattg caactggtgc
     3841 tgatgaaatc atcatccctg aagcaggctt caagatggaa gatatcgtag caagcatcaa
     3901 agctggttat gaatgtggta aaaaacacaa tatcatcgtc ttagctgaag gtgtgatgtc
     3961 agcggctgaa tttggtcaaa aacttaaaga agctggagat acaagcgacc ttcgtgtaac
     4021 agaacttgga catattcaac gtggtggttc tccaactgcg cgtgaccgtg ttttggcgtc
     4081 acgtatgggt gcacatgctg ttaaacttct taaagaaggt atcggtggtg ttgcggttgg
     4141 tattcgtaac gaaaaaatgg ttgaaaatcc aattcttggt actgcagaag aaggggcatt
     4201 gtttagcctt actgcagaag gtaagattgt ggttaacaac ccgcacaaag ccgatattga
     4261 gctatctagc ttgaataaga gcttgtcata atttacaatt tagttaataa gaccaaaaag
     4321 gtcatatata taaaggagtc acaaaaatca tgaacaaacg tgtaaagatc gttgcaactt
     4381 tgggtcctgc ggtagaaatc cgtggtggta aaaaattcgg tgaggatgga tactggggtg
     4441 aaaaacttga tgttgaagct tcagctaaaa acattgctaa attgattgaa gctggtgcta
     4501 acacattccg attcaacttc tcacacggcg accaccaaga acaaggtgag cgtatggcaa
     4561 ctgttaaact tgcggaaaaa attgcaggta aaaaagttgg tttccttctt gatacaaaag
     4621 gacctgaaat ccgtacggaa ttgttcgaag gtgaagctaa agaatattca tacaaaactg
     4681 gtgaaaaaat tcgtgttgca actaaacaag gaatcaaatc aactcgtgaa gtgattgcgt
     4741 tgaacgttgc tggtgctctt gatatctatg atgatgttga agttggtcgt caagttttgg
     4801 ttgacgatgg taaacttggt cttcgtgtgg ttgctaaaga tgatgcaact cgtgaatttg
     4861 aagttgaagt tgaaaacgat ggtatcatcg ctaaacaaaa aggtgtgaac atccctaaca
     4921 ctaaaattcc tttcccagct cttgctgaac gcgataacga cgatatccgt ttcggtcttg
     4981 aacaaggtat caacttcatc gcaatttcat tcgtacgtac tgcaaaagat gtgaacgaag
     5041 ttcgtgcaat ctgtgaagaa actggaaacg gacatgttca attgttcgct aaaatcgaaa
     5101 accaacaagg tatcgataac ttagacgaaa tcatcgaagc agctgatggt attatgattg
     5161 ctcgtggtga tatgggtatc gaagtaccgt tcgaaatggt tccagtttat caaaaaatga
     5221 ttatcaagaa agtcaatgct gcaggtaaag ttgttatcac tgcaacaaac atgcttgaaa
     5281 caatgactga aaaaccacgt gcaactcgtt cagaagtatc agacgtattc aacgctgtta
     5341 tcgacggaac tgacgctaca atgctgtcag gcgagtctgc aaacggtaaa tacccactcg
     5401 agtcagtaac tacaatggct acaatcgaca agaacgctca agctcttctt aatgaatacg
     5461 gacgtcttga ttcagattca tttgagcgta actctaagac agaagtaatg gcttctgctg
     5521 ttaaagatgc tactagctca atggatatca aattggttgt aactcttact aagacaggtc
     5581 atactgcacg tttgatttct aaataccgtc caaatgctga catcttagca ttgacatttg
     5641 acgaattgac agaacgtggc ttgatgttga actggggtgt tatcccaatg ttgacagatg
     5701 ctccatcttc aactgacgat atgttcgaaa tcgctgaacg taaagcggta gaagcaggtc
     5761 tcgttgagtc aggcgatgat atcgttatcg ttgctggtgt gccagtagga gaagctgttc
     5821 gcacaaacac aatgcgtatc cgcacagtac gttaagaaaa atataaaaac ctatcatatc
     5881 cagctttaga gcttgtgtga taggcttttt gtatagaggg taagaaatag gcaaaacttt
     5941 cataatggat tgatactctt cgaaaatctc ttcaaaccac gtcagcgtcg ccttaccgta
     6001 catatgttac tgacttcgtc agttctatct acaacctcaa agcagtgctt tgagcaacct
     6061 gcggctagct tcctagtttg ctctttgatt ttcattgagt atgaaataag atatgcacaa
     6121 attgattaga aagtcaaatg aatttctaca aatgttttag caatcgcaat ctacttgtct
     6181 agattcgatc tgatatattt tcgatttaat gatatggtat ttaaaacctc caaagtagct
     6241 tgctccattc ttttacttac gtgagtgtag atgttattta ctgttttagc gtttttgtgt
     6301 tccactctaa ccattatagc attcttctca gctagtgtac taaggagtgt gtgcctgaaa
     6361 atatgggaac taaggggctg gtttatcggt ttctctagtt tagtatttgc cttttgcaaa
     6421 gtgatcttaa atgcctttct ctaaatttac atatcactat tgtttaacaa aatctaatct
     6481 attttaggtc acttattctt tttttgaaat gtagaatgaa ctttttcaaa gtttttcgaa
     6541 tcttttaaaa tctgtttgtt ttatatcgcc attctccccc ttttttaatt ctccctatat
     6601 agcctgacaa cttttccgat ggtacgaata tggttgcttt cgtctaggtg gatgtcggag
     6661 tattcgggat tgagtttttt tgaggtagcc ttggcggagt ttcttgacat agttagtgcc
     6721 gtctacttgg aagatgccga tggtattata gtcaatctgt ggggtattct tgataaatag
     6781 gtagtcgctg tttcttatct ttggctccat ggacttgctg acgacataag cgattgggtc
     6841 gtagtcgtct gggataatgg aaactccata actaaatcgt cgtcctgcat caagcggcta
     6901 cctgcagaga taaactacct aacacgagag taagtagtct gtctgtagtc gtccagtctg
     6961 atgattttta cgatacttcg tttttctgat catacagttg cctctcggca taggtcagga
     7021 ctttaccttg tctgggtggt acccgttggt cgtagataga ttggatatcg ctaggagaat
     7081 ccttttgaac tggaggaaag agggcatcaa tcaagctact gaatacttta actaagtcaa
     7141 atatagtatt tttcttagta gacctaaccc ttttttcata atttctaatg gtgtttttac
     7201 ttatacctat cttagtaccc aattcttatt gagtccaact attactagtc tatattgttt
     7261 tatagttgat tgagtttgga atagtacgct gtagctgcta aaacatttct aggaattaat
     7321 ttgcctttcc taatagagtt gttcatatct tatttcaatc tattatgttt ttcacctcta
     7381 acaatcgcaa tctcttcttt atctatgaat gaaatcgatt tctatttttg taagtaaagc
     7441 ataacacgaa atccacgaaa atgaaaacct ttgttgtgtt ttcgtaaaaa atttgttgac
     7501 agagcacgga acgcctacta taattaaatc aagcttaagg aaataacaaa aaaacaaatc
     7561 ggagggaaag acgatgaaca cattaaatga gaaagtaatc aatatctgta aagcagtagt
     7621 taaagaaact ttaatccaag acatttagga gaaagaaatg aagaaatcaa gaaaattagc
     7681 cacattagga atctgttcag ctttgttttt aggattggct gcttgtcaac aacaacatgc
     7741 tacttctgag gggacgaatc aaaggcaaag cagttcagcg aaagttccat ggaaagcttc
     7801 atacaccaac ctaaacaacc aggtaagtac agaagaggtc aaatctctct tatcagctca
     7861 cttggatcca aatagtgttg atgcattttt taatctcgtt aatgactata ataccattgt
     7921 cggctcaact ggcttatcag gagatttcac ttcctttact cacaccgaat acgatgttga
     7981 gaaaatcagt catctctgga atcaaaagaa gggcgatttt gttggaacca actgccgtat
     8041 caatagttat tgtcttttga aaaattcagt caccattcca aagcttgaaa agaatgacca
     8101 gttgcttttc ctagataatg atgcgattga taaaggaaag gtctttgatt cacaagataa
     8161 ggaagagttt gatattctat tttcgagagt tccaactgag gcaactacag atgtcaaggt
     8221 tcacgctgaa aagatggaaa cattcttctc acaatttcaa ttcaatgaaa aagctcgaat
     8281 gctgtctgta gtcttgcacg acaatctgga tggcgagtat ctgtttgtag gccacgttgg
     8341 ggtcttagta cctgctgatg acggtttctt atttgtagag aaattgactt tcgaagagcc
     8401 ctaccaagcg attaaatttg ctagtaagga agattgctac aagtatttgg gcaccaagta
     8461 tgcggattat acaggcgagg gactggctaa gccttttatc atggataatg ataagtgggt
     8521 taaactttaa tagtgttatg atatgacagt aatcttagga tttttatttc tatttttgat
     8581 gacttggtgg gttatttcaa tcgttaatag ccagaaacca cgcaaaaatg aaacatttat
     8641 tggctatatc caaagatacg atattgatgg gaatggctat caatcattac cgtgtcctca
     8701 gaactgagag gagttcttga aatcgtaaaa ctactttgaa caagagttac ttcaacccat
     8761 tggctccgac ggattaagtt gctttcgtga acaccaaaat cagccgcaat ttcttcataa
     8821 gtgcggtatt ctcgcacata ttgaagagtg gccataagaa ggtcttctag gcttaattta
     8881 ggttttcgtc ccccttttgt gtgtttaagt tgataagcag tttttaatac agctaacatc
     8941 tctttaaaag tggtgcgctg aacaccaaca agacatttaa atcgtgcatc agttagttgc
     9001 ttacttgctt cataattcat agaactacta taccatattt tgtttcgcag gaagtctaat
     9061 gctaaaatct tatcagtgag aagatttctt aaagtttatt ctttgtagtt tcatctgtat
     9121 tagtatataa tttaacttag agaaaatagg aggactaatc gaatggaatt aaaagatttt
     9181 acagaaaaag aacaggaaat gattaagaaa aggcttacaa tgtctaatat tagtgacaaa
     9241 gaaactactg agaagattct ggcgctagta ccacaagact tgattaagcg aatcccgttt
     9301 tttgtcagaa aacatgctac aacacgtacg attaaacgca tttcaattga acaccctgaa
     9361 ctctacgctg tagctcaaac aagtggtgag attccagaaa aagaacgcga agaattgcgt
     9421 cagattatca caactatctt tgaacaaaag atgaataagc atagtattaa gtagagaatg
     9481 aaaaaatatt ttattagcgg tttgggaagc aatgcctatc atagcaagga tttttttcaa
     9541 gaactagatt cgcaggtcta ttttctaaat ccatatgaaa agcatcttcg agatgaaaca
     9601 gaattgaaat catggtttaa aaatgagatt gtagaggaag aatctatctg tctgataggt
     9661 cattctcttg gaggagattt agctcgttat ttcgcatcgg aatttgaaga agtaaagaaa
     9721 ctgattcttt tggatggtgg ctatctagat ttagataaga ttttaccttt ggatacagag
     9781 ttagaggaaa ctaaaaatta tatcaaatct caaattgttt tggacttaga tgttcttact
     9841 tctaaagaaa aatctgaagc aaagcattgg tcagaaaata tggagaaagc tgtaagacag
     9901 tcctatcact ggaatgttga gtataataga tatgagttgg ctataaatta tgaaaatata
     9961 gaagctatac tccgcctacg gagaaaaata caagctttta agagagaagt gggagatacc
    10021 ttgtttatta gtcctcgcta tcctaatgga gctacatgga gagaggaagc cctaaaagaa
    10081 ttgccagact attttgatac tattttttta gaaaactttg gccatgagct ttatactcaa
    10141 gcacctaaag aaatctctag tctaatgaat gagtggctcg cttattttct atgagctact
    10201 tgtattgctg gaaatggtat aagatgaaaa tctacaagtc actaattttt atataacaaa
    10261 aaaacgaaca ggctcttttt ctgttattca gaagagaact tgttcgtttt tatcttgatt
    10321 ttcttaaaaa gctctatata catagggatt ttctggttta tcgactttgg taaagctatc
    10381 gatttccaag gtcgggagat tttgtttgag ttctttatgg tagtgattga ccagttttcc
    10441 tttggctgtt atccaagtgt tgttctcata ttgacgggta tttcccttgg tcagcaaccc
    10501 atagacacca gaatctgcga tacagtggat aatgccgaat cggaacagaa attgactatt
    10561 ggcatgactg gggtcgttat agacaaagcc tgtaaactgg attgtcttgc cctcaaactc
    10621 atctggatag tcgtagatag cctccatgac ttccatatag ttttcattag tgatctgaat
    10681 actatcttgg gataagtatt tatccgccgc cgttcgcatt tccttttcat aggctgattt
    10741 tgaaaaataa gaactggtat ctggtttcaa atattggctt gtcgtccctt cgcttgtctg
    10801 aatggctaga tccgttcctt ccgatagggg gaaatgataa cctttagcag aaacagtctg
    10861 agaatccaag ctaacagttg ggaaagttaa gccgatgaca agtggaatag ccagaagaga
    10921 aatactcgtc atcttggcca atcggctgtt cagatgactg tgggttttga cttgcttcat
    10981 ccagatatac aattgaacaa ttgccaagat aaaggaaagc accatggaaa tataggccag
    11041 ataggaatag tgcatgttga tgtactggtt tagtttgccc gacagatgga ggtaaatagt
    11101 cagttcaaaa tagccagcta aaactaaaaa tcgaatcata ggatgactcc aatcaagaga
    11161 gaataggcta aaacgaccag agtcacaatc gtaatgaagt gactaataaa tcgtgctttc
    11221 aagtaatttt tcatcatgag aatatttttg atatccagca ttgggccaat gacgagaaag
    11281 gccagaactg gagccaaacc gaaactcgag agtagagaag cacctataaa ggcatccgcc
    11341 tcactacaga gcgaaagaag aaaggccaaa agcatcaaga gcaggatggc aaaaagagga
    11401 gtcgcactga tagaggtcag aatccgagtc ggaacgtaga cctgtattat agaagcaaag
    11461 aggcagccaa ataccaaata acgccccgta tcaaaaaatt catcaatggc ctgcacaaag
    11521 acttgaaaaa ctttttttgc agaactcaag taagaaaaat catgctcatg acaagccaga
    11581 cgattttctt tctgaatcgg ttcttgccag aaaaatccta gaaaaattcc tagtattaca
    11641 gccacaagaa tggaacccag agctcgtaat agggcgacat ggaaggagtt gccaaaggca
    11701 gaataggtcg caaaaagaac aatgggattg ataacaggtg ctgtcacaag aaaaggaact
    11761 gccgtgtaac ttggaacctt tttttccaga aaacgattga tgatggggac gattccacat
    11821 tcacaagaag ggaaaagtat accgacaaag gtcccaaaaa agattctccc ccaacgattt
    11881 cgagggagaa aatgataaac cttgtcaggt gtgatataaa cttcaatcag ccctgagaca
    11941 atgcttccta tcagaacgaa gggaagggct tcaatgataa tggagagaaa aatggctcca
    12001 gtttgaagta cactagatgg gagttgttga aaagcagtca tctagttttt cttttctgct
    12061 ttgacttttt tctctttgtc atcagggaaa gtaacttgtt tcaaatcagg gagtttagca
    12121 aactcttcaa acatcttgtc caagtcgtct cgttttgtaa atttgacagc cataggtgta
    12181 cctcgattct aaattctacc tctattatac tattattttg cggaaaaggg agttttttaa
    12241 tttgttttcg atagttgata cacttcgaaa atctcttcaa accacgtcag cttcgcctta
    12301 ccgtagtacg gttactgact tcgtcagttc tatccacaac ctcaaaacag tgttttgagc
    12361 tgacttcgtc agtcttatcc acaacctcaa aacagtattt tgagcagcct gcggctagct
    12421 tcctagtttg ctttttgatt ttcattgagt atgaaaagga ttggagaaag ccttccagct
    12481 tgtggtataa tagatttatg gataaaaaat atgaaaaaat ctctcaggat ttgggagtga
    12541 cgttaaagca aattgatacc gttctaagtt tgacagctga aggggcgact attcccttta
    12601 tcgcgcgtta tcgcaaggac atgactggta gtctggatga ggtggcgatt aaggctatta
    12661 ttgatttgga taaaagtctg acaaatctca atgaccgtaa ggaagctgtc ttagctaaga
    12721 ttcaagaaca aggtaagttg accaaggaat tggaagaagc tatcttagtt gccgaaaaat
    12781 tagcagacgt tgaagaactc tatcttcctt ataaggaaaa gcgtcgtacc aaggcaacca
    12841 ttgcccgtga agctggactc tttcctcttg ctcgcttgat tttgcagaat atagttgact
    12901 tagagaaaga agctgaaaag ttcgtctgtg aaggatttgc gactggcaag gaagccttga
    12961 ccggtgcagt tgatattttg gtcgaagcct tatcggaaga tgtgaccttg cgttctatga
    13021 cttatcagga agtgctgaga cactctaaac ttacttctca agccaaggat gaaagtcttg
    13081 atgaaaagca ggtttttcag atttattatg atttttcaga gacagttgga actatgcaag
    13141 gctatcgtac cttggctctc aatcgtgggg agaaacttgg tgtcttgaag atcggttttg
    13201 aacatgcgac ggaccgtatt cttgccttct ttgctactcg tttcaaggtg aaaaatgttt
    13261 atattgatga agttgttcag caatccgtta agaaaaaggt cttgcctgct atcgagcgtc
    13321 gtattcggac agaattaact gagaaagctg aagaaggagc tatccaactt ttttctgaca
    13381 atctgcgcaa tctcctcttg gttgctccac tgaaagggcg cgtggttctt ggatttgacc
    13441 cagcctttcg tacaggtgcc aagttagctg tcgtggatgc aacaggaaaa atgctgacaa
    13501 ctcaggttat ttatcctgtt aaaccagcat cagctcgtca aatcgaagaa gccaagaaag
    13561 atttagcaga tttaattggt caatacggtg tagagattat tgccattgga aatggaacgg
    13621 ccagtcgtga aagtgaagct tttgtagcgg aagttctgaa agatttccct gaagtcagct
    13681 atgttatcgt taatgaaagt ggtgcttctg tctattctgc cagcgaactt gctcgtcagg
    13741 agtttccaga cttgaccgtt gaaaaacgtt ctgccatttc tatcgcccgt cgtttgcaag
    13801 atcctcttgc ggaattggtc aaaatcgatc ctaagtcaat tggtgtcggt caataccaac
    13861 acgatgtcag tcagaagaaa ctatctgaga gtctggactt tgttgtcgat acagtggtta
    13921 accaagttgg tgtcaatgtc aatacagcta gcccagctct tctttcacac gtagctggac
    13981 tcaacaaaac tatctctgaa aatattgtca aataccgcga ggaagaagga aaaatcactt
    14041 cacgcgccca aatcaagaaa gttcctcgtc tgggagccaa ggcctttgag caggctgctg
    14101 gtttccttcg tatccctgaa agtagcaata tccttgataa tacaggagtt cacccagaga
    14161 attacactgc agttaaggaa ctcttcaaac gtttagatat taaagaccta aacgaagaag
    14221 cccaaagcaa actcaagtcc ctttcagtca aggaaatggc tcaagagcta gacctcggtc
    14281 cagaaaccct taaagatatc attgcagatc ttctcaaacc aggtcgagat ttccgtgatt
    14341 cctttgacgc acctgtgctt cgccaagatg tcctagatat caaagaccta gtggtaggtc
    14401 agaagctaga aggtgttgtg cgtaacgttg ttgacttcgg tgccttcgtt gatatcggga
    14461 ttcacgagga cggcttgatt catatttctc atatgagtcg caagtttatc aaacacccta
    14521 gtcaagtggt gtcagttgga gatttggtga ccgtttgggt caagaaaatt gatactgaac
    14581 gtgaaaaagt taatctgtcg ctcctcgctc caaatgaaac tgactgatta tgtcaagcag
    14641 gtttcactag aagacttcgg gagagctttt atccatcatg tccagtggaa taggcgtcta
    14701 cgttcgacag gtgggcgatt tttccccaaa gatgggcatc tggattttaa tcccaaggtt
    14761 tatcagaaac tgggtatgga ggtttttagg aaaattgtcc gacatgaact ctgtcattat
    14821 cacctttatt tccaagggaa gggctatcaa cacaaggatc gggattttaa ggaacttttg
    14881 aaagcagtgg atggattacg gtttgtacca tccttgccca atagtaactc taaaccactc
    14941 aagctttatc gttgtcaatc ctgccagcaa aggtatcagc gcaagcgtag gattgatacc
    15001 aaacgctatc gctgtggact ttgtcgaggt aaattgcttc tgataaatca gcctgaggac
    15061 tgatgaaagc cgagcctccc cgtgatatac tatgtctaac ctagcagaaa gaggaaatat
    15121 catgaacagt aaattttata aaatgagacg caatcgcatg atttcaggag ttctggcagg
    15181 tctgtcagac aagtggaatt ttgatgttac cctagttcgt ttcttgtttg ctatttttac
    15241 agttgcaaac tttggacttg gcgtgattat ctatatcatc ctagcttcta tcatgcctac
    15301 caaggaagaa atcgaagcag aaatgtacgg aacaggccca cgtaaacgca aagaagccca
    15361 agccattgac gacaatgaag gctggttttg gtgaggttct acagaagatt tggaataagc
    15421 aaaaagcttt aaatcaatag tctaaactgc ttgatttaaa gcttttttac ttttatactc
    15481 aataaaaatc aaagtgcaaa ctaggaagcc agccacaggc tgtaatttag tcggcaatgt
    15541 gaagttgaca tagtttgcac tttgattttt gaatagtatt aataatattt cgccagcttc
    15601 atccacaaac tatagtggat tggaactaga atagtacacc tctacttcta aaacattgtt
    15661 agaaatcgat ttgactatcc tgatcgattt gtcctgttct tatttcattt tattataaaa
    15721 gcagtaattt aaacgcagtt ttttaatcta tttttgctgc tgagacaata tatttttgga
    15781 aaaatggtgg atgctgataa caactgataa ccagcaaata acataagcag tgccggtaaa
    15841 ttctgtaccg ataaagtgtg tgtgttcaac taagagctga ccgatgaatg gagagagcag
    15901 atagagaagt ccgatgagta tatgttcttt gtgtttcatt aaagcgcacc ttctttcctt
    15961 ataggttgaa cgacttgcaa gtgttaaatt gaatggtatg ttatctaggt aaccttacta
    16021 aaatgttagt tcccgcttcc tccttttcaa agtaagcctt ttcacactta tattttacaa
    16081 ctttaaaaat aggaaatcaa atcattttct aagtaatttt gcttatattt cacccaatct
    16141 tacaaaaatg taagattaaa gtctcttttg taaggttagg ttatggcaag cggtcttttt
    16201 ttgatgtaaa ctagactcat aaagaacaaa ggagtaacat catgaaacaa atcttacata
    16261 agaaaactag aaaaccaagt cacaaagaaa ttgagcgcgt tcagctggga tgcactatga
    16321 tgcaagctac atttcatttg atgggatatt aagaaaggag attctcatga cacttttaga
    16381 tgtaaaacac gttcaaaaaa tttataaaac acgttttcag ggcaaccaag tagaagccct
    16441 caaggatatt cactttaccg tcgaaaaggg tgactacgtt gccatcatgg gtgagtctgg
    16501 ttctggtaaa tcaactcttc tcaatattct agctatgctg gataaaccaa gtcgtggtca
    16561 ggtttacttg aatggaactg acaccgcaac cattaaaaat tcacaggcct ctagcttccg
    16621 tcgtgaaaag ttgggctttg tcttccaaga ctttaacttg ctagatactc tatctgtaaa
    16681 ggacaatatc ttgcttccgc ttgtcttgtc aagaagacct attacagaga tgatgaagaa
    16741 attggtggtg acagctgaga atctgggaat aaaccaatta caagagaagt acccttacga
    16801 gatttctggt ggtcagaaac agcgtgtagc agtagcccgc gccatcatca cagaacctga
    16861 aattctcctt gcggacgaac cgacaggagc tcttgactcc aagtcatctg cagccttact
    16921 tgatgtcttt gatgaaatca atgagcgcgg ccaaaccatt ctcatggtaa cccactcaac
    16981 agcagcagct agcagagcta aacgtgtact ctttatcaaa gacggcattc tttacaatca
    17041 aatctaccgt ggagagaaga cagaacgtca gatgttccaa gaaatctctg ataccttgac
    17101 tgtcatggca agcgaggtga attagtatgt ttcgattaac caataagtta gcggtatcga
    17161 acttgattaa aaaccgcaaa ctctactatc cttttgcgct ggctgttctc ttggcagtca
    17221 ctgtcaccta tctcttttac tctctaacct tcaatcctaa gattgcggaa atccgtggag
    17281 gaacaaccat tcaggctaca cttggatttg gtatgtttgt cgtcaccctt gcgtcagcca
    17341 ttatcgttct ctatgccaat agttttgtca tgaagaaccg ttccaaggaa ctaggaattt
    17401 atggcatgtt gggcttggag aagcgtcatc ttatcagtat gacctttaag gagttagtgg
    17461 tatttgggat tctaactgtt ggagcgggta tcggtattgg agccttgttt gacaagttaa
    17521 ttttcgcttt cctgctcaaa ctaatgaaat tgaaggttga gctggttgct accttccaga
    17581 cgaaagttgt cattacagtg cttgttgtct tcggtttgat tttcctaggc ctcatgttcc
    17641 tgaatgccct tcgaatcgcc cgtatgaatg ccctccagct ctctcgtgag aaagctagtg
    17701 gagagaaaaa aggtcgcttc cttcctctcc aaaccattct tggttccata agtttaggaa
    17761 ttggctatta tcttgccctt acggtaaaag atcctcttac agccttaaca accttcttca
    17821 tagctgtttt actggttatc tttgggactt atctcttgtt taatgcaggg attaccgttt
    17881 tcctccaaat cttaaagaaa aataagaaat actattacca accaaataac ctcatatctg
    17941 tttctaactt gattttccgt atgaagaaaa atgcagttgg actagccacc atcgctatct
    18001 tgtcaacaat ggttttggta accatgtcag cagcgacaag cattttcaat tcctcagaaa
    18061 gctttaaaaa agttctaaat cctcatgatt ttggggtttc agggcaaaat gttgaaaaag
    18121 aagacttgga caaactcttg agccagtttg caagtgacaa aggttataag attaaagaaa
    18181 aagaagtatt tcgttacact tactttgctg ttgcgaatca agaaggaacc gagttaacta
    18241 tttttgaaaa aggacaaaac cgtgtccaac caaaaacaat tttcatggta tttgaccaaa
    18301 aagattatga aaatatgact ggtcaaaaac tgtctctatc aggaaatgag gtcggactct
    18361 ttgcaaagaa tgagggagtt aaagaacaga aaactctaat tctgaatgat catcaatttt
    18421 ctgtaaaaga agaatttaat aaagatttta ttgtcaagca tgtcccaaat cagtttaata
    18481 ttttgactgc tgattacaat taccttgttg tacctgattt acaagccttt ttgaaccaat
    18541 tcccagattc ggctatctat aatcagtttt acggtggtat gaatgtaaat gtcagtgaag
    18601 aagagcaact caaagtcgct gaagaatatg aaaaatactt acaaaagttt aatgctcaat
    18661 taaacactga aggtaactat gtgtatggta gcactctagc agatgctagt gctcaaatga
    18721 gtgtcctctt tggcggtgtc ttctttatcg gtattttcct atccattatc tttatggtcg
    18781 gaaccgttct ggtcatctac tacaaacaaa tttctgaagg atatgaagac cgtgagcgct
    18841 ttattatctt gcagaaagtc ggtttagatc aaaagcaaat caagcaaacc atcaacaaac
    18901 aggttttaac tgtattcttc cttcctttgc tctttgcctt cctacatcta gcctttgcct
    18961 accatatgct tagtctgatt ttaaaagtga ttggtgtact ggatacgact atgatgttga
    19021 ttgtgacctt gtctatctgc gctatcttcc tcatcgccta tgtgctgatt ttcatgatta
    19081 cttcaagaag ttatcgcaag attgtgcaaa tgtaaaaaag atacctcgac ttcaaaatcg
    19141 aggtatttct tgtattctaa atgctgaaaa gttgttcgag caggaaggta actcccatgg
    19201 tcaagagacc aatagcaagg ttccgaatca tagctgtttt ggttggggct tttccaagtc
    19261 tagcacttgt gtaaccagtg agaagaaggg ccacaccgac aataaggacg gtagcaggga
    19321 tgcggtaatc acttggaaaa atggtcactg acagcattgg aggcaaactt ctaaggaaaa
    19381 aggcaacgaa gctagaaatg gcagcgtgcc aaggattggt aaattcttca tactaaatcc
    19441 catatttttc ctctaccaga gccttgagtg gatttttaag aaagatctta ttggtcaaga
    19501 gttgggcaga agttttgaat tctccatttt ggatataagc agcatagagg gattttttgg
    19561 ctagttccct atcttggtct agcaagagtt tttctcgcga aacggcagct tcctcggtat
    19621 cttttggagt tgaaacggat acatattctc caccagccat tgaaaaggca ccagctaaga
    19681 tagccgcaaa accggataaa aagataatcc agatattgct cgtggcactg gcaactccga
    19741 taaccacacc agcaatggaa ataattccat cgttagcatc aagaacaccc gcacgcagga
    19801 tatttaaacg acctgcaaaa tttgaatcaa tttcgtgatt tgtttctgac gctaaatttc
    19861 aagttcaagt tagccatcca gaagtcttct ctgggtgact tgtagtccaa gcatttttta
    19921 ggatagttgt taatccactt ttcgatgaat gcgacttctt tgggagtcat tttcttggtt
    19981 cccttaggta actatctacg aatgagcctg ttgtgattct cattagttcc cctttcccaa
    20041 gaggcatagg ggtgcgcata atagatgtgc tcctcagaaa atatatcaaa caagcgattg
    20101 aattccgttc cattatctgc cgtgatggaa agaatcttgt gttgttttaa gatgagtttt
    20161 agagcctgat tgaccacctc agcactttta tttggaatca atcggatgat ctgatgtcta
    20221 ctctttcgat ccgtcaagac aagcaagcag tagtttttcg atctcgtaag tagaaccgta
    20281 tcaatctcat aatgcccatt ctccaagcga agattgatag cttcaggccg ctgttcgatg
    20341 gattgaccag caggtttaaa gttggtgcta gcctgtttct taagcgcttt tccttttcta
    20401 gggtaaagca gatcctgctt gcttaacccc aattttccat gatgaatcca atagtaaatg
    20461 gttgaaattc ccacgttaac ccctttagcc ataaccatca tttcaggcaa aaatttttgg
    20521 ttatgatagt ggagaatctt ttcctttagt tccttggtca cgcttgatct cttgaccgag
    20581 tgcttgcgat tattttcata agactgttga gcatagtcgg cagaataaac ctctttgaag
    20641 cgcccttttc caagacattt tcggactgtc ctacgcttga tttcagtgtg gatagtttga
    20701 ggagcttttc caagtagaga ggcaatttct ctatttgatt ttccttcttt tttccatctt
    20761 tcgattaagc gacggctatc gattgtcaaa tgtttacctt ttgtagtata attgtcttgc
    20821 atttctgtgc ctttcttgtg tttgtggttg aacaacaagt ataacacaga ggtgttttct
    20881 tatgcctaca agagctttca gctagttgaa ccatctaatt tttaggaggg ctgggtggct
    20941 aacttcatta tagaactttc atttacgaac atatagtaaa atgaaacaag aacagaacaa
    21001 atcgatcagg acagtaaaat ctatttctaa caatgtttta gaagcagagg tgtactattc
    21061 tagtttcaat ctattatatt tttgtttttt atcaaaaaat actttacaag ttcttaaaaa
    21121 catgatatag taataaagct tagaaaatga gatgatgttt tctagcaaat ataaacccga
    21181 gtaaaaaatg cctacggaca ggcagggttg aatgccgaag cgtggttgaa aagccacatt
    21241 attgataggg ttaaaagcct acttttataa gttgatgtta ggacacttgt cctaattcat
    21301 aaatttttag tgtggtgaaa gcacacgtca tcttgtgaaa cgatcaataa agtacgtaat
    21361 atttgctact agagagttag gaaacatcgg gaacagacat actcaacaga aaccaaaata
    21421 aacacgtcag aagattgcag agcaggtgaa aacctgctct tttttcatga gtcaaccttt
    21481 agttccttag ttttcataag gtcctaaaaa tattgaaagg agtatgtttt gaaagagtta
    21541 gatcaaaacc aagccccaat ttatgaggcc ttggtgaagt tacgcaagaa aaggattgtt
    21601 ccctttgatg ttccaggtca caagcgtgga cggggaaatc cagaacttgt cgaactctta
    21661 ggagaaaaat gtgtaggcat tgatgtcaat tcgatgaaac ccttggataa tttaggccat
    21721 cctatttcga ttattcgtga tgcagaggag ctggctgcag atgcttttgg agctagccat
    21781 gcctttctaa tgattggtgg aacaacttca tcggtgcaga ctatgattct ggcaacctgc
    21841 aaggcaggag ataagattat tctgccacga aatgtccata aatctgctat caatgcgttg
    21901 gttctatgtg gtgccattcc catctatatc gagatgagtg tagatcctaa gattggtatc
    21961 gctttaggtc ttgaaaatga ccgagtagca caggccataa aggaccatcc agatgctaag
    22021 gctaccctaa tcaacaatcc tacttactac ggcatctgtt cagacctaaa ggggttgaca
    22081 gaaatggctc atgaagctgg catgatggtt ttagtagatg aagcccatgg agcgcatttg
    22141 catttcactg gtaaacttcc aatttctgct atggatgcag gagctgatat ggcagcagtt
    22201 tccatgcata agtctggtgg gagtttgaca caaagttcgc ttcttttaat cggggagcag
    22261 atgagtcccg agtacgttcg tcagattata aacttgaccc agtctacatc tgcctcttac
    22321 ttattgatgg ctagtttgga tatttcacgt cgcaacttgg cccttcgtgg taaagagtcg
    22381 tttgaggaag tcattgagct atccgagtac gctcgtcatg aaatcaatgc cattggcggt
    22441 tactatgctt actcaaaaga gttaatagat ggtgtgtcgg tctgtgattt tgatgtaacc
    22501 aagttgtcag tttacactca gggaataggc ttaacaggta tcgaggttta tgacctcttg
    22561 cgagacgaat acgacattca gatcgagttt ggtgatatcg gcaatatctt ggcctatatt
    22621 tccatcggcg accgcatcca agacatcgag cgcttggttg gtgctctggc tgatattaag
    22681 agactctatt cacgagatgg gaaggactta atagctggag aatatattca gcccgagttg
    22741 gtgctgtctc cacaagaagc cttctattca gagagaaaaa gtttgacctt agatgagtct
    22801 gttggacagg tctgtggaga atttgtcatg tgctatcctc cagggattcc tatcttggct
    22861 cctggtgaac gcattacacg agaaattgta gactatatcc aattcgccaa ggaacgtggt
    22921 tgctccctcc aagggacgga agatccagag gtcaatcata tcaacgttat taagagaaag
    22981 acaaactata agaaaagtca atagttttat ctaaactatt tcttatttca atttgatgat
    23041 ttggcgatga ttttagagca cggcaaaaag cccttgaatt agaagcggtc aatcgcttaa
    23101 tttctatcag cttatcaaat cctgcctcaa tccttttctg aggattaggg tagcgtgtca
    23161 agagttggta ggtatattct gaatgctttc caacgatttt atccaactca ggaaagatga
    23221 tatcaagaca acgagtgtat tgtactttcc aatcagactg tttttcttga gacgatgaat
    23281 atgtctagcc agtattttta gttctacttg ccgattatcg tgttgaaatt gttcacgatt
    23341 ggggtcagaa agaagtttaa gagcgatgcc atgagcgtct ttcttatccg ttttagtctt
    23401 gcgaagtgat aatgatttgg caaattcctt gatgagcaaa ggattgtagg tgtaaacttt
    23461 atatccttgt tcatgcagga agttcagtag attaaaggca taatgtccgg tattttcaag
    23521 agcgatgaga cagtcttggt tgagttgtcg aagagacaga tctaagagtt caaaaccagc
    23581 tttattattt gaaaaagtga gtggtttaag aacagttttt cctggaacat tcaaggctgt
    23641 aacatcgtgt ttatttttag cgacatcaat gcccacataa agcatgggag tacctccaga
    23701 tgtagtattt caagtctact tggttatcca cgaatttttt gccttgttac cttagacgag
    23761 ataaaacgtc tatgcgttat caaactcatt accaattgaa acaaaaaact gtggttagag
    23821 cctttcggaa atcgtcaagc gattggaggg aataaactaa tccacagtgg cttattccaa
    23881 gtataccact tgggctttgg cagtagctaa ctgcgctaaa tataatataa ggagaaatag
    23941 atggatttat ggttttctga agttcatact ccagatgtca aattgtctct gagaacagcc
    24001 aagcaacttt acgctggaaa aagtgaatgg caggatatcg aagtcttgga tacgccagct
    24061 tttgggaaaa tactgatttt aaatggccat gtcttgttct cagatgcgga tgatttcgtc
    24121 tacaatgaaa tgaccgttca cgttcccatg gctgtccacc caaatccaaa gaaagtattg
    24181 gttattgggg gtggtgacgg cggtgttgcc caagtattaa cactctatcc tgaactggaa
    24241 caaatcgata tcgtggaacc ggatgagatg ttggtcgagg tctgtcgtga gtatttccca
    24301 gactttgctg cagggctaga tgatcctcgt gttaccattt actaccaaaa tgggctacgc
    24361 tttttgcgaa actgcgaaga tgattacgat attatcatca acgatgcgac agatccattt
    24421 ggccatacgg aaggactctt taccaaggaa ttctacggca atagttatcg agctctgaag
    24481 gaagacggca tcatgattta ccagcatggg agtcccttct ttgacgagga tgagtcggcc
    24541 tgccgaagca tgcaccgcaa ggtcaatcaa tcctttccaa tcagtcgggt ttatcaggcc
    24601 catattccaa ctagcccagc tggctattgg ttgtttggat ttgcatcgaa aaaataccac
    24661 cctgtcaaag attttgacaa ggaaggttgg aaaaaacgcc agcttttcac agaatactac
    24721 actgcaaact tacacgtggg atcctttatg ttgcccaagt atgttgagga cattttagaa
    24781 gaagaggaag gaaaaaaatg agtcgtttac tagttattgg ttgtgggggc gttgcccaag
    24841 ttgctatttc aaagatttgt caagatagcg aaacatttac agagattatg attgctagcc
    24901 gtaccaagtc aaaatgcgat gacttgaaag cgaagctaga aggcaaaaca agtactaaaa
    24961 ttgaaactgc agcacttgat gctgacaagg ttgaagaagt gattgccctg attgaaagct
    25021 acaaaccaga agctgttttg aatgtagctc tgccttatca agatttaacc attatggatg
    25081 cttgtttggc aacaggtgtt cactatatcg atacagccaa ctacgaagca gaagacacag
    25141 aagaccctga gtggcgtgct atctacgaaa aacgttgtaa ggaacttggt tttacagcct
    25201 actttgacta ctcatggcag tgggcttatc aagagaaatt caaagaagca ggcttgactg
    25261 ctcttcttgg ttctggcttt gacccaggtg taactagtgt cttttcagct tatgccctca
    25321 aacactattt tgatgaaatc cattatatcg acattttaga ctgtaatggc ggtgaccacg
    25381 gttatccatt tgcaaccaac tttaatccag aaattaatct ccgtgaggtt tctgcgccag
    25441 gttcttactg ggaagatggg aaatgggtcg aagtcgaagc tatgtctatc aagcgtgagt
    25501 atgatttccc tcaagttgga caaaaagata tgtatctcct tcaccatgaa gaaatcgaat
    25561 cattggccaa gaacattcca ggtgtcaaac gcattcgttt ctttatgact tttggtcaat
    25621 cttacttgac gcacatgaaa tgtcttgaaa atgttggact ccttcgtacg gataccatta
    25681 actttaacgg ccaagaaatt gttccaattc aatttttgaa agccttgctt ccagatcctg
    25741 ctagccttgg cccacgtact gtaggtaaaa ccaatattgg atgtatcttt acaggtgtca
    25801 aagatggcgt tgaaaagact atctacatct acaatgtttg cgaccatcaa gagtgctatg
    25861 cagaagtcgg gtcacaagca atttcataca cgacaggcgt tccagccatg attgggacaa
    25921 aattagtcat gaacggaact tggaaacaag ctggagtgta taaccttgag gagttagatc
    25981 cagatccatt catggaagct ttgaatgagt atggtttgcc atgggttgtg gttgaaaatc
    26041 cacaaatggt ggactaatga agttagaaca agtaccaaca ccagcctatg ttattgactt
    26101 ggccaagtta gaagctaatt gccgcattct acaatatgta caagaagagg tcggttgcaa
    26161 ggtcttgctt gcccagaagg catattccct ctacaaaact tatcccttga ttagccagta
    26221 tctatcaggt acgacagcta gtggactcta tgaggccaaa ttggcaaggg aagaatttcc
    26281 tggtgaagtc catgtatttg cgcctgcttt caaggatgca gacttggagg aattgcttgg
    26341 gataacagac catatcgtct ttaactcaga gagacagttg cgtaagcatg gggctcgttg
    26401 tcgagaggct ggtgtcagtg ttggtttgcg cctcaaccct cagtgttcaa ctcaaggaga
    26461 tcacgcgctc tatgaccctt gtgcaccagg ttctcgcttt ggagttacta tagacaagat
    26521 tccgagtgat ttgctagatt tggttgacgg acttcatttt catacccttt gcgagcaggg
    26581 agcagatgat ttacaaacaa ctttgaaagc agtagaagaa cagtttggtc cctacttaca
    26641 tgaggtaaaa tggctcaata tgggtggtgg tcatcatatt acaagagaag gttacgatgt
    26701 ggatttgctg atttcagaaa tcaagcgtat ccgaaaaact tacaatcttg aaatctatat
    26761 cgagcctggt gaagccattg cgcttaatgc gggttattta gcaactgagg tattagatat
    26821 tgtagaaaac ggtatggaaa tcttggtttt agacgcctct gcgacctgcc atatgcctga
    26881 tgtacttgag atgccctatc gtccaccttt gagaaatggc tttgaggcac aggaaaaagc
    26941 ccatacctac agactttctt ctaatacctg tctgacgggc gatgtgattg gtgattatag
    27001 ttttgaaaat ccagtccaaa tcggagacag actttatttt caagacatgg ccatttattc
    27061 ttttgtcaaa aataatacct ttaatggtat tggattgcca agtctctatc tcatggacga
    27121 acagggagac tgtagcttac tcaaagcttt tggctatcaa gactttaaag ggagattatc
    27181 atgatggaca gtccaaaaaa attaggctat cacatgccag cagagtacga accccatcat
    27241 ggtaccctca tgatatggcc gactcgacca ggatcatggc cttttcaagg aaaggctgct
    27301 aaaagagcat ttactcagat catcgagacc atagcagaag gggaaagagt ctatcttttg
    27361 gtggagcagg cctatctata tgaagcccaa tcctatcttg gagacaaggt tgtttattta
    27421 gacattccca ccaatgatgc ctgggcgcgt gatactggcc caaccattct cgtcaatgat
    27481 aaaggtaaga aattagccgt ggattgggcc ttcaatgctt ggggaggcac ctatgatggt
    27541 ctttatcaag attatgaaga ggatgaccaa gtagccagtc gttttgctga ggtcttggaa
    27601 aagcctgtct atgatgctaa accttttgta ctggaaggag gcgcaatcca tagcgatggt
    27661 caaggaacta ttctcgtaac tgaaagttgc ttgcttagtc ctggtcgcaa tcctaacctg
    27721 actaaagagg agattgaaaa cacattatta gaaagtcttg gtgctgaaaa agttatttgg
    27781 cttccttatg gtatttatca ggatgaaacc aatgaacacg tcgataatgt tgctgccttt
    27841 gttggttctg ctgagcttgt tttggcttgg acagatgacg aaaatgatcc ccagtatgcc
    27901 atgtcaaaag cagatctcga actcttagaa caggaaacag atgcaaaagg ttgtcacttc
    27961 accattcata aattgcctat ccctgcagtt cgacaagttg tgacagaaga agatttgcca
    28021 ggctacatct atgaagaagg agaagaagag cgatacgcag gtgaacgact agcagcttcc
    28081 tacgtaaact tttatatcgc caacaaggct gtcttggttc cacagtttga ggatgtaaac
    28141 gaccaagtgg ccatagatat cctcagcaag tgtttcccag accgtaaagt tgtcggaata
    28201 ccagccagag atattctctt aggtggtggc aatatccact gtatcaccca acaaattcca
    28261 gaataggaga aaaagatgag aaatgtaaga gttgcaacca ttcagatgca atgcgctaag
    28321 gatgtggcaa caaatatcca aaccgcagag cgtttagtac gtcaggctgc tgagcaagga
    28381 gcccaaatta ttctcttgcc cgagttgttt gaacatccct atttctgtca ggaacgtcag
    28441 tatgactact accagtatgc ccaatctgta gcggaaaata ctgcaattca gcattttaag
    28501 gtgattgcta aggaactaca agttgtttta ccaatcagtt tctatgaaaa agatggtaat
    28561 gtcttgtata actctattgc cgtcattgat gcagatgggg aagtgctggg cgtttatcga
    28621 aagacccaca taccagatga ccattattat caagaaaaat tctatttcac gcctggtaac
    28681 actggtttca aggtctggaa tactcgctat gctaagattg gtatcggtat ctgttgggat
    28741 caatggttcc ctgaaacagc gcgctgtctt gcattgaatg gtgctgaatt gctcttttat
    28801 cctacagcta tcggttcaga gccaattttg gatacagata gttgtggtca ctggcaacgt
    28861 actatgcaag ggcacgcagc agcgaatatt gttccagtca tcgcagccaa tcgttatggt
    28921 ttagaggagg ttactcctag tgaggaaaat ggcggacaga gttccagtct tgacttctac
    28981 ggttcctcct ttatgacgga tgaaacagga gctattctag aacgagctga aagacaagaa
    29041 gaagctgttc tgttagctac ttatgaccta gacaagggag caagtgaacg cctaaactgg
    29101 ggcttgtttc gagatagaag accagaaatg tatagacaaa ttacagatta gtgtgggaga
    29161 aatgagagat tcattctgct agactaactt cttattagca actataagat actatggcat
    29221 ctagtaaatc gatttttatg attcgctatt cttgtctatt gattagtccg tattttaaaa
    29281 tattagcaaa aaagcaaata gcagtaactt ctgtctattt gcttttcttt tttatagagt
    29341 atatttctca atagcacgcg caacgccgtc ttcttcgttg cttgaggtaa cggcatccgc
    29401 aagagatttg acataatcgc tggcatttcc cattgcaatc ccaagccctg caaactggag
    29461 catttcgata tcgttattag catcgcccat ggccataatc tctgaggaat caatcttcaa
    29521 aatctcagct agtcgtgaaa gagcagtagc ctttgtcgtt ccaagcggca ttgcttcata
    29581 aatgacaggc tgcgaacgaa ctccactgaa tcgttggcaa agctcttcag caaaacgctg
    29641 ctcaaaatcg tctgtttgtt cttttgttcc taaaaacata ccttggaaca tccggaactt
    29701 tccactagtc gcttcttcaa gagaaatttc agtcaggtct gaaaatacta gtttagcatc
    29761 attttcaata acttgattgg gtttgccacc gagaacaaaa taatgtgact cgtcaaaaag
    29821 tgtcaactga acatcactct tttcagcaag gtcatagagg tattcgatgt cagctggact
    29881 cagttctttc cagtcaacta gactccaatc actggtctgg tgagttgaac aaccgttgtt
    29941 aacaataata tattcgttct ggaggtcaag ctccagtttt ttgtagtagg ggaggacacc
    30001 gaaaaggggg cgacccgtac agagaaccag tttgacacct ttttcaatgg ctttgtgaat
    30061 agcagtaatg tgagcttgtg ggatttcctt ggcttcattg aggagggtgc cgtccatatc
    30121 caaggctagt agtttaatca taggtcttcc ttctttatct tttgctatta ttatagcata
    30181 tttttgagaa gaaattgata gaaagcttga gactaattga ttttatagtt taagatgttt
    30241 tgatgacaat tcatgatttg aagaggatat ttcgcaaaga tatgctatac tatgtttgtc
    30301 aatgttgcaa ctagacaaat taaaaaacca acttaatata atagtttttt tgtaagtagg
    30361 tatgagtatc agattactca actaatctga agaataatgg aggaaatata tcatgatttt
    30421 aatgacaaaa aatataaatc taacaaatga agaattagag ctgatacaag gtggagcaga
    30481 tccatatggt aaaaatccta atggtaggta cgattgggaa atagaaccag tattaactct
    30541 gccggttcat ggattttgtc ccagaggcac ctatgattta ggatatattg gaggaggcaa
    30601 tcatctttgc aaaggaagtg ctgcgagatt ttaagtaaaa tttattagta atatgaagaa
    30661 acaagtggag aaagcagaga atttaatatg aaaaaacggg ctattcaaat tttactagca
    30721 ttgtccttaa ttttttacaa atcaacttgg ttttggagag ttttcaatca cctcgcaaag
    30781 ccctatctac cagcaagtcg tgaatttttt cagattctgc ttttgatgga gagcggagtt
    30841 cttttcttag cggtcatcta tctactggtt tttgcaggaa agaaaatttt tcatttcaag
    30901 tggcagctga ggtacttcat ctacctttta ctgggctaca tcatttcata tatgtctgac
    30961 ttcctctttt cgtatttcat atccctgtct tcaaatcaga tttctttgaa tgaaacggta
    31021 gaaatgatgg ggagacagga gttcccttat ttcttgctca tcgtttgctt catcgcccct
    31081 attgctgagg aattgattta tcgaggtgtg cttatgacaa cctttttcaa aaactcacct
    31141 tggtacggag atgttttgct ttctgctatt attttcggtt atattcatat caattttgct
    31201 ttaactcctc ttgctttttt catttatgct agtggaggtc ttattttagc tctattgtat
    31261 cgcatgacta aaaatctcta ctatccaata ctagttcata ttctcatcaa tatcactgcc
    31321 ttctgggatg tttggttact cctattttca ggaagttagc ttactaaaaa aatgtcggaa
    31381 ttttccggca ttttcttttt tcacaaatag tcaacgtttt tctttccgat actgaagtgg
    31441 tgtgtagcca cttatttttt tgaattgatt ttgaaaataa gattggcgtg agaaaggcag
    31501 atagtgaaga tagttaagaa gaataggatg ttcttttttc ctttttggaa aacttctaaa
    31561 atatggtata atgaaaagat aaagaagttg ggggtagaag atgaacattc aacaattacg
    31621 ctatgttgtg gctattgcca atagtggtac ttttcgtgaa gctgctgaaa agatgtatgt
    31681 tagtcagccg agtctgtcta tttctgttcg tgatttggaa aaagagttgg gctttaagat
    31741 tttccgtcgg accagctcag ggactttctt gacccgtcgt gggatggaat tttatgaaaa
    31801 agcgcaagaa ttggttaaag gatttgatat ttttcaaaat cagtatgcca atcctgaaga
    31861 agaaaaagat gaattttccg ttgctagcca gcactatgac ttcttaccac caactattac
    31921 ggccttttca gagcgctatc ctgactataa gaacttccgt atttttgaat caactactgt
    31981 tcaaatatta gatgaagtgg cgcaagggca tagtgagatt gggattatct acctcaacaa
    32041 tcaaaataaa aaggggatta tgcaacgggt tgaaaagtta ggtctggagg tcatcgaatt
    32101 gattcctttc catacccata tttatctctg tgagggtcat cctttagctc agaaagagga
    32161 attagtcatg gaggatttag cggatttacc aacggttcgt ttcactcaag agaaagacga
    32221 gtacctttat tattcagaga actttgtcga taccagcgct agctcacaga tgtttaatgt
    32281 gacagaccgt gccaccttga atggtatttt ggagcggacg gacgcctatg cgacaggttc
    32341 tggattttta gatagtgaca gtgttaatgg cattacagtt attcgtctca aggataacct
    32401 agataaccgc atggtctatg ttaaacgtga agaagtggag cttagtcaag ctgggactct
    32461 cttcgtagaa gtcatgcaag aatattttga tcaaaagagg aaatcatgaa aaaaagagca
    32521 atagtggcag tcattgtact gcttttaatt gggctggatc agttggtcaa atcctatatc
    32581 gtccagcaga ttccactggg tgaagtgcgc tcctggattc ccaatttcgt tagcttgacc
    32641 tacctgcaaa atcgaggtgc agccttttct atcttacaag atcagcagct gttattcgct
    32701 gtcattactc tggttgtcgt gataggtgcc atttggtatt tacataaaca catggaggac
    32761 tcattctgga tggtcttggg tttgactcta ataatcgcgg gtggtcttgg aaactttatt
    32821 gacagggtca gtcagggctt tgttgtggat atgttccacc ttgactttat caactttgca
    32881 attttcaatg tggcagatag ctatctgacg gttggagtga ttattttatt gattgcaatg
    32941 ctaaaagagg aaataaatgg aaattaaaat tgaaactggt ggtctgcgtt tggataaggc
    33001 tttgtcagat ttgtcagaat tatcacgtag tctcgcgaat gaacaaatta aatcaggcca
    33061 ggtcttggtc aatggtcaag tcaagaaagc taaatacaca gtccaagagg gtgatgtcgt
    33121 cacttaccat gtgccagaac cagaggtatt agagtatgtg gctgaggatc ttccgctaga
    33181 aatagtctac caagatgagg atgtggctgt cgttaacaaa cctcagggaa tggttgtgca
    33241 cccgagtgct ggtcatacca gtggaaccct agtaaatgcc ctcatgtatc atattaagga
    33301 cttgtcgggt atcaatgggg ttctgcgtcc agggattgtt caccgtattg ataaggatac
    33361 gtcaggtctt ctcatgattg ctaaaaacga tgatgcgcat ctagcacttg cccaagaact
    33421 caaggataaa aagtctctcc gcaaatattg ggcgattgtt catggaaatc tgcctaatga
    33481 tcgtggtgta attgaagcgc cgattggccg gagtgaaaaa gaccgtaaga aacaggctgt
    33541 aactgctaaa gggaagcctg cagtgacgcg ttttcacgtc ttggaacgct ttggcgatta
    33601 tagcttagta gagttgcaac tggagacagg gcgcactcat caaatccgtg tccacatggc
    33661 ttatatcggc cattcagtcg ctggtgatga ggtctatggt cctcgcaaga ctttgaaagg
    33721 acatggacaa tttcttcatg ccaagacttt aggttttact catccgagaa caggtaagac
    33781 cttggaattt aaagcagata tcccagagat ttttaaggaa accttggaga gattgagaaa
    33841 gtaagaatga aaaagaaatt aactagttta gcacttgtag gcgctttttt aggtttgtca
    33901 tggtatggga atgttcaggc tcaagaaagt tcaggaaata aaatccactt tatcaatgtt
    33961 caagaaggtg gcagtgatgc gattattctt gaaagcaatg gacattttgc catggtggat
    34021 acaggagaag attatgattt cccagatgga agtgattctc gctatccatg gagagaagga
    34081 attgaaacgt cttataagca tgttctaaca gaccgtgtct ttcgtcgttt gaaggaattg
    34141 ggtgtccaaa aacttgattt tattttggtg acccataccc acagtgatca tattggaaat
    34201 gttgatgaat tactgtctac ctatccagtt gaccgagtct atcttaaaaa atatagtgat
    34261 aatcgtatta ctaattctga acgtctatgg gataatctgt acggttatga taaggtttta
    34321 cagactgctt cagaaaaagg tgtttcagtt attcaaaata tcacacaagg ggatgctcat
    34381 tttcagtttg gggacatgga tattgagctc tataactatg aaaatgaaac cgattcatcg
    34441 ggtgaattaa agaaaatttg ggatgacaat tccaattcct tgattagcgt ggtgaaagtc
    34501 aatggcaaga aaatttacct tgggggcgat ttagataatg ttcatggagc agaagacaag
    34561 tatggtcctc tcattggaaa agttgatttg atgaagttta atcatcacca tgataccaac
    34621 aaatcaaata ccaaggattt cattaaaaat ttgagtccga gtttgattgt tcaaacttcg
    34681 gatagtctac cttggaaaaa tggtgttgat agtgagtatg ttaattggct caaagaacga
    34741 ggaattgaga gaatcaacgc agccagcaaa gactatgatg caacagtttt tgatattcga
    34801 caagacggtt tagtaaacat ttcaacttcc tacaagccga ttccaagttt tcaagctggt
    34861 tggcataaga gttcatatgg aaactggtgg tatcaagcgc ctgattctac aggagaatat
    34921 gctgtcggtt ggaatgaaat taagggtgaa tggtattact ttaaccaaac gggtatctta
    34981 ttacagaatc aatggaaaaa atggaacaat cgttggttct atttgacaga ctctggtgtt
    35041 gctgctaaaa attggaagaa aatcgctgga atctggtatt attttaacaa agaaaaccag
    35101 atggaaattg gttggattca agataaagag cagtggtatt atttggatgt tgatggctct
    35161 atgaagacag gttggcttca atataagggg caatggtatt actttgctcc atcaggggaa
    35221 atgaaaacgg gctgggtaaa agataaagaa gcctggtact atatggattc tactggtatc
    35281 atgaagacag gtgagataga agttgctgga catcattact atctagaaga atcaggagct
    35341 atgaagcaag gctggcttaa aaaggcaaat gattggtatt tctacaagac agatggttca
    35401 cgagctatag gttggattaa agacaaggat aaatggtact tcttgaaaga aaatggtcaa
    35461 ttacttgtga atggtaagac accagaaggc tatactgtgg attcaagtgg tgcctggtta
    35521 gtggatgttc cgatcgagaa atctgctaca attaaaacta caagtcattc agaaataaaa
    35581 gaatccaaag aagtagtgaa aaaggatctt gaaaataaag aaacgagtca acatgaaagt
    35641 gttacaaatt cttcaactag tcaagatttg acatcctcaa cttcacaaag ctctgaaacg
    35701 agtgtaaaca aatcggaatc agaacagtag tagaaaagaa ggttttaggg ccttcttttt
    35761 cctatcaact cttttctatt tcctgttatt catgttataa tggataaata tgaataatcg
    35821 gagtgagact atgaaataca aacggattgt ctttaaggtg ggtacttctt ctctgacaaa
    35881 tgaggatgga agtttatcac gtagtaaggt aaaggatatt acccagcagt tggctatgct
    35941 gcacgaggct ggtcatgagt tgattttggt gtcttcaggt gccattgcgg ctggttttgg
    36001 agccttagga tttaaaaagc gtccgactaa gattgctgat aaacaggctt cagcagcggt
    36061 agggcaaggg cttttgttgg aagaatatac aaccaatctt ctcttgcgtc aaatcgtttc
    36121 tgcacaaatc ttgctgaccc aagatgattt tgtggataag cgtcgttata aaaatgccca
    36181 tcaggctttg tcggttttac tcaatcgtgg ggcaattcct atcatcaatg agaatgatag
    36241 tgtcgttatt gatgaggtca aggttgggga caatgacact ctaagtgccc aagtagcggc
    36301 gatggtccaa gcagaccttt tggttctctt gacagatgtg gacggtctct atactggaaa
    36361 tcctaattca gatccaagag ccaaacgctt ggagagaata gagaccatca atcgtgagat
    36421 tattgatatg gctggtggag ctggttcgtc aaacggaact gggggtatgt taaccaaaat
    36481 caaggctgca actatcgcga cggaatcagg agttcctgtt tatatctgct catccttgaa
    36541 atcagattcc atgattgagg cggcagagga gaccgaggat ggttcttact ttgttgctca
    36601 agagaagggg cttcgtaccc agaaacaatg gcttgccttc tatgctcaga gtcaaggttc
    36661 tatttgggtt gataaagggg ctgcggaagc tctctctcaa catggaaaga gtcttctctt
    36721 atctggtatt gttgaagcag aaggagcctt ttcttacggt gatatcgtga cagtatttga
    36781 caaggaaagt ggaaaatcac ttggaaaagg acgcgtgcaa tttggagcat ctgctttgga
    36841 ggatatattg cgttctcaaa aagctaaggg tgtcttgatt taccgtgacg actggatttc
    36901 cattactcct gaaatccaac tactttttac agaattttag aggtaaacta tggtgagtag
    36961 acaagaacaa tttgaacagg tacaggctgt taaaaaatcg attaacacag ctagtgaaga
    37021 agtgaaaaat caagccttgc tagccatggc tgatcactta gtggctgcta ctgaggaaat
    37081 tttagcggct aatgccctcg atatggcagc ggctaagggg aaaatctcag atgtgatgtt
    37141 ggatcgtctt tatttggatg cagatcgtat agaagcgatg gcaagaggaa ttcgtgaagt
    37201 ggttgcctta ccagatccaa tcggtgaagt tttagaaaca agtcagcttg aaaatggttt
    37261 ggttatcaca aaaaaacgtg tagctatggg tgtcatcggt attatctatg aaagccgtcc
    37321 aaatgtgacg tctgatgcgg ctgctttgac tcttaagagt ggaaatgcgg ttgttcttcg
    37381 tagtggtaag gatgcctatc aaacaaccca tgccattgtc acagccttga agaagggctt
    37441 ggagacgact actattcacc caaatgtgat tcaactggtg gaagatacta gccatgaaag
    37501 tagttatgct atgatgaagg ccaagggcta tctagacctc ctcattcctc gtggaggagc
    37561 tggcttgatc aatgcagtgg ttgagaatgc gattgtacct gttatcgaga cagggactgg
    37621 gattgtccat gtctatgtgg ataaggatgc agacgaagac aaggcgctgt ctatcatcaa
    37681 caatgctaaa accagtcgtc cttctgtttg taatgccatg gaggttctgc tggttcatga
    37741 agataaggca gcaagcatcc ttcctcgctt ggatcaaatg ctggttgcag agcgtaagga
    37801 agctggactg gaaccaattc aattccgctt ggatagcaaa gcaagccagt ttgtttcagg
    37861 tcaagcagct gagacccaag actttgacac cgagttttta gactatgtcc ttgctgttaa
    37921 ggttgtgagc agtttagaag aagcggttgc gcacattgaa tcccacagca cccatcattc
    37981 ggatgctatt gtgacggaaa atgctgaagc tgcagcatac tttacagatc aagtggactc
    38041 tgcagcggtg tatgttaatg cctcaactcg tttcacagat ggaggacaat ttggtcttgg
    38101 ttgtgaaatg gggatttcta ctcagaaatt gcacgcgcgt ggtccaatgg gcttgaagga
    38161 attgactagc tacaagtatg tggtcactgg tgatggacag ataagggagt aagagatgaa
    38221 gattggattt atcggtttgg ggaatatggg tgctagttta gccaagtctg tcttgcaggc
    38281 tagaccgtca gatgagattc tccttgccaa tcgtagtcaa gtcaaggtgg atgctttcat
    38341 cgctaacttc ggtggtcaga cttctaacaa tgaagaaata ttcgaagaag cagatgtgat
    38401 ttttctaggt gttaagcctg ctcagttttc tgaactgctt tctcaatacc agaccatcct
    38461 tgaaaaaaga gaaagtcttc ttttgatttc gatggcagct ggattgatct tagaaaaact
    38521 agcaagtctt atcccaagcc aacaccgaat tattcgtatg atgcctaata cccctgcttc
    38581 tatcgggcaa ggagtgatta gttatgcctt gtctcctaat tgcagggctg aggacagtga
    38641 gctcttttgt cagcttttat ccaaggctgg tctcttggtt gaattaggag aaagcttaat
    38701 caatgcagcg acaggtcttg caggctgtgg accagccttt gtctatctct ttattgaggc
    38761 cttggcagat gcaggtgttc agacgggatt accacgagaa acagccttga aaatggcagc
    38821 ccaaactgtg gtaggagctg ggcaattggt cctagaaagc cagcaacatc ctggagtttt
    38881 gaaagatcaa gtttgtagtc caggcggttc gactattgct ggcgtagcaa gcctagaagc
    38941 gcatgctttt cgaggaacgg tcatggaggc agttcatcaa gcctataaac gaacacaaga
    39001 actaggtaaa taagaggtag ttttatctgc ctcttttatg gtggttgata ctcttcgaaa
    39061 atcaaattca aactgcgtca gcttcacctt gccgtactca agtacagcct gcggctagct
    39121 tcctagtttg ctctttgatt ttcattgagt atgaaatgag aagacaaaaa gattgtcaca
    39181 aacccctatt tttttgatag aatagaagta gtaaaaaaga aatgagttag acatgtcaaa
    39241 aggattttta gtctctcttg agggaccaga gggagcaggc aagaccagcg ttttagaggc
    39301 tctgctacca attttagagg taaaaggggt aaaggtgctg acgacccgtg aacctggcgg
    39361 agtcttgatt ggggagaaga ttcgggaagt gattttggat ccaagtcata ctcagatgga
    39421 tgctaaaaca gagctacttc tctatattgc cagtcgcaga cagcatttgg tggaaaaagt
    39481 tcttccagcc cttgaagctg gcaagttggt catcatggat cgttttatcg atagttctgt
    39541 tgcctatcag ggatttggtc gtggcttaga tattgaagcc attgactggc tcaatcagtt
    39601 tgcgacagat ggcctcaaac ccgatttgac actctatttt gacatcgagg tggaagaagg
    39661 gctggctcgt attgctgcta atagtgaccg cgaggttaat cgtttggatt tggaagggtt
    39721 ggacttgcat aaaaaagttc gtcaaggcta cctttctctt ctggataaag agggaaatcg
    39781 cattgtcaag attgatgcta gtctcccttt ggagcaagtt gtggaaacta ccaatgctgt
    39841 cttgtttgac ggaatgggct tggccaaatg aaacaagatc aactaaaggc ttggcaacca
    39901 gctcagtttg accgttttgt ccgtatctta gaacaagacc agctcaatca cgcctatctc
    39961 ttttcaggtt tctttggaag cttggaaatg gcgcaatttt tagctaagag ccttttttgt
    40021 acggataaag ttggcgtctt accatgtgag aaatgccgaa gttgcaagct gattgaacag
    40081 gaagagtttc cagatgtcac cttgattaag ccagtcaatc aggtcatcaa gacagaacgc
    40141 attcgggaat tggtgggaca gttttctcaa gcagggattg aaagccagca acaggtcttt
    40201 atcatcgagc aagcggataa aatgcatccc aacgcagcca attctctgct caaggtcatc
    40261 gaagaacccc agagtgaagt ttatattttc ttcttgacta gcgatgagga aaagatgtta
    40321 ccgacaatcc gaagtcggac tcagatcttc cactttaaaa agcaagaaga aaaacttatc
    40381 ttactcttag aacaaatggg acttgttaag aaaaaagcga ctcttttagc taagtttagt
    40441 caatcgcgag ctgaagcaga aaagttggca catcaggcaa gtttttggac cttggtcgat
    40501 gaaagtgaac gcctgctgac ttggttagta gctaagaaaa aagaaagtta tctacaggtt
    40561 gccaaattag ccaacttggc agatgataag gaaaaacagg atcaggtttt acggattctt
    40621 gaagttctct gtgggcagga cctcttgcag gtaagagtaa gagtgattct acaagattta
    40681 ctagaagcta gaaaaatgtg gcaagctaat gtcagctttc aaaatgccat ggaatatctg
    40741 gtcttgaaag aaatataaac tcaaaaatga atgataaaga aaggaaaggg ctgttttatg
    40801 gacaaaaaag aattatttga cgcgctggat gatttttccc aacaattatt ggtaacttta
    40861 gccgatgtgg aagccatcaa gaaaaatctc aagagcttgg tagaagaaaa tacagctctt
    40921 cgcttggaaa atagtaagtt gcgagaacgc ttgggtgagg tggaagcaga cgctcccgtc
    40981 aaggccaagc atgttcgcga aagtgtccgt cgtatttacc gtgatggatt tcacgtatgt
    41041 aatgattttt atggacaacg tcgagagcag gacgaagaat gtatgttctg tgatgagttg
    41101 ttatacaggg agtaagcatg cagattcaaa aaagttttaa ggggcagtct ccctatggca
    41161 agctgtatct agtggcaacg ccgattggca atctagatga tatgactttt cgtgctatcc
    41221 agaccttgaa agaagtggac tggattgctg ctgaggatac gcgcaataca ggtcttttgc
    41281 tcaagcattt tgacatttcc accaagcaga tcagttttca tgagcacaat gccaaggaaa
    41341 aaattcctga tttgattggt ttcttgaaag cagggcaaag tattgctcag gtctctgatg
    41401 ccggtttgcc tagcatttca gaccctggtc atgatttggt taaggcagct attgaggaag
    41461 aaattgcagt tgttacagtt ccaggtgcct ctgcaggaat ttccgccttg attgccagtg
    41521 gtttagcgcc gcagccacat atcttttacg gctttttacc gagaaaatca ggccagcaaa
    41581 agcaattttt cgactcgaaa aaagactatc ctgaaactca gattttttat gaatcgcccc
    41641 atcgtgtggc agatacattg gaaaatatgc tagaagtcta cggtgaccgc tcggtagtct
    41701 tggttagaga attgaccaaa atctatgaag aataccaaag aggtacaatt tctgaattgc
    41761 tggaaagcat ctctgaaacg tctctcaagg gtgaatgtct tctgattgtt gaaggtgcca
    41821 gcaaaggtgt ggaggaaaag gatgaggaag acttgttctt agaaatccaa gcccgtatcc
    41881 agcaaggcat gaagaaaaat caagctatta aggaagtcgc taagatttac cagtggaata
    41941 aaagtcagct ctacgctgcc taccacgact gggaagaaaa tcaagaaaat gactaaacag
    42001 ggaagtttgc cttcttccct ttttttgtta tactagtaga agaaaaaatt agaaagattt
    42061 gtgggtgtta aacaagccag tgccttgttt tgatatgaac ttaggttcca cccaaagagg
    42121 tattagtgtc gtgtctcaat cttatatcaa tgttatcggt gctggtttgg caggttctga
    42181 agcagcttac caaatcgcag agcgtggtat tccagttaaa ctatatgaaa tgcgtggtgt
    42241 caagtctaca ccccagcata aaacagacaa ttttgctgag ttggtttgtt ccaattcttt
    42301 gcgtggggat gctttgacaa atgcagttgg tcttctcaag gaagaaatgc gtcgcttggg
    42361 ttctgttatc ttggaatctg ctgaggctac acgtgttcct gccggtggag cccttgcggt
    42421 ggatcgtgat ggtttctctc aaatggtgac cgaaaaagtt gccaaccacc ccttgattga
    42481 agtggttcgt gatgaaatta cagaattgcc gacagatgtt attacggtta tcgctactgg
    42541 tcctttgaca agtgatgcct tggctgaaaa gattcatgcc cttaatgacg gtgatggttt
    42601 ttatttctac gatgcggcag cgcctattat cgatgtcaac actatcgata tgagcaaggt
    42661 ctacctcaaa tcacgttatg ataagggaga agcggcctac ctcaatgccc ctatgaccaa
    42721 gcaagaattt atggatttcc atgaagcttt ggtcaatgca gaagaagcac cgcttaattc
    42781 ttttgaaaaa gaaaagtact ttgaaggatg tatgcctatc gaagttatgg ccaaacgtgg
    42841 cattaaaact atgctttatg gccctatgaa gccagtcggt cttgagtatc cggacgacta
    42901 cacaggacct cgtgatggag aatttaaaac accttatgcg gttgtgcaac ttcgtcagga
    42961 taatgcagct ggtagcctct acaatatcgt tggtttccag acccacctca aatggggaga
    43021 acaaaagcgt gtcttccaaa tgattccggg tcttgaaaat gcggagtttg tccgttatgg
    43081 tgtcatgcat cgcaattctt acatggattc accaaatctt cttgagcaga cttaccgttc
    43141 caagaaacaa ccaaatctct tctttgctgg tcagatgacg ggggtggaag gctatgttga
    43201 gtcggcggct tcgggcttag ttgcgggaat taacgcagct cgtctcttca aggaagaaag
    43261 cgaggttatt ttccccgaga cgacagcgat tggaagctta gctcattaca ttacccatgc
    43321 cgacagcaaa catttccaac caatgaatgt caattttggg atcatcaagg agttggaagg
    43381 cgagcgtatc cgtgataaga aggctcgtta tgaaaaaatt gcagagcgtg cccttgccga
    43441 cttagaggaa tttttgactg tctaattttt ttgaaagaat tgctcatgat actataaaaa
    43501 tcttagaaat tgtgataaaa taggtaggat gaaagaagga gagtgaaaat ggcgaatccc
    43561 aagtataaac gtattttaat caagttatca ggtgaagccc ttgccggtga acgtggcgta
    43621 gggattgata tccaaacagt tcaaacaatc gcaaaagaga ttcaagaagt tcatagctta
    43681 ggtatcgaaa ttgcgcttgt tattggtgga ggaaatctct ggcgtggaga acctgcagca
    43741 gaagcaggta tggaccgtgt tcaggcagat tacactggaa tgcttgggac tgttatgaat
    43801 gctcttgtga tggcagattc attgcaacaa gttggggttg atacgcgtgt acaaacagct
    43861 attgctatgc aacaagtggc agagccttat gtccgtggac gtgcccttcg tcaccttgaa
    43921 aaaggccgta tcgttatctt tggtgctgga attggttcac catacttctc gacagataca
    43981 acagcggccc ttcgtgcagc tgaaatcgaa gcagatgcca tcctcatggc taaaaatggc
    44041 gtcgatggtg tgtacaatgc cgatcctaag aaggacaaga cagccgttaa gtttgaagaa
    44101 ttgacccacc gtgatgttat caacaaaggt cttcgtatca tggactcaac agcctcaacc
    44161 ctctcaatgg acaacgacat tgacttggtt gtcttcaaca tgaaccaatc aggcaacatc
    44221 aaacgtgtcg tatttggtga aaatatcgga acaacagttt caaataatat cgaagaaaag
    44281 gaataagaaa gaatatggct aacgtaatta ttgaaaaagc taaagagaga atgacccagt
    44341 ctcaccaatc acttgctcgt gaatttggtg gtatccgtgc tggtcgtgcc aatgcaagct
    44401 tgcttgaccg tgtacatgta gaatactatg gagtcgaaac tcctcttaac caaatcgctt
    44461 caattacgat tccagaagcg cgtgttttgt tggtaacacc atttgacaag tcttcattga
    44521 aagacatcga acgtgccttg aacgcttctg atcttggtat cacaccggct aatgacggtt
    44581 ctgtgattcg cttggttatc ccagctctta cagaagaaac tcgtcgtgac cttgctaaag
    44641 aagtgaagaa ggtcggcgaa aatgctaaag tggctgtccg caatatccgt cgcgatgcta
    44701 tggacgaagc taagaaacaa gaaaaagcaa aagaaatcac tgaagacgaa ttgaagactc
    44761 ttgaaaaaga tattcaaaaa gtaacagacg atgctgttaa acacatcgac gatatgactg
    44821 ccaacaaaga gaaagaactt ttggaagtct aaaaataaac agaaaaactc agttggcatt
    44881 gctggctgag ttttattcga aagaaggaaa tatgaataca aatcttgcaa gttttatcgt
    44941 tggactgatc atcgatgaaa acgaccgttt ttactttgtg caaaaggatg gtcaaaccta
    45001 tgctcttgct aaggaagaag gccaacatac agtaggggat acggtcaaag gttttgcata
    45061 cacggatatg aagcaaaaac tccgcctgac aaccttagaa gtgactgcca ctcaggacca
    45121 atttggttgg ggacgtgtca cagaggttcg taaggacttg ggtgtctttg tggatacagg
    45181 ccttcctgac aaggaaatcg ttgtgtcact cgatattctc cctgagctca aggaactctg
    45241 gcctaagaag ggcgaccaac tctacatccg tcttgaagtg gataagaaag accgtatctg
    45301 gggtctcttg gcttatcaag aagacttcca acgtcttgct cgtcctgcct acaacaacat
    45361 gcagaaccaa aactggccag ccattgttta ccgtctcaag ctatcaggaa cttttgttta
    45421 cctaccagaa aataatatgc ttggttttat tcatcctagc gagcgttacg cagagccacg
    45481 tttggggcaa gtattagatg cgcgcgttat tggtttccgt gaagtggacc gcactttgaa
    45541 cctctccctc aaaccacgct cctttgaaat gttggaaaac gatgctcaga tgattttgac
    45601 ttatttggaa agcaatggcg gtttcatgac cttaaatgac aagtcatctc cagacgacat
    45661 caaggcaacc tttggcattt ctaaaggtca gttcaagaaa gctttaggtg gtcttatgaa
    45721 ggctggtaaa atcaagcagg accagtttgg tacagagttg atttagggag gcttatgaga
    45781 aaatcatttt acacttggct catgaccgag cgcaatccta aaagtaacag tcccaaagca
    45841 attttggcag acctcgcttt tgaagagtca gcctttccaa aacatacaga tgattttgat
    45901 gaggtcagtc gctttttgga ggagcatgcc agtttctctt ttaacctagg agattttgac
    45961 agcatttggc aggaatatct agaacactag catttattca ttgggtttgg gctagtaatt
    46021 tctccatccc tctgctataa taaaaagaaa taaaaggatt agagaggttc tttatttgaa
    46081 ggaacattca atagacattc aactgagtca tccagatgac ctgtttcatc tttttggttc
    46141 caatgaacgc catcttcgtt tgatggaaga agagcttgat gttgtgattc atgctcgtac
    46201 ggagattgtc caggttttgg gagaagagtc tgcctgtgag gaagcccgtc aagttattca
    46261 ggctttgatg gtcttggtaa atcgtgggat gaccgttggt acgccagatg tagtcactgc
    46321 gattagcatg gtcaaaaatg atgaaattga caagtttgtc gccctttacg aagaagaaat
    46381 tatcaaagat aatactggga aacctatccg tgtcaaaacc ctagggcaaa agctttatgt
    46441 ggacagtgtc aaacagcatg atgtgacctt tggaattggg ccagcaggta cagggaagac
    46501 cttccttgca gtgaccttgg cagtgactgc ccttaaacgt gggcaagtca agcgaattat
    46561 cctaactcgt ccagcggtgg aagcgggaga gagtcttgga tttcttccgg gtgatcttaa
    46621 ggagaaggtg gatccttacc ttcgtcctgt ttacgatgcc ttgtatcaaa ttcttgggaa
    46681 agaccaaacg actcgtctca tggagcgtga aattatcgaa attgcgcccc ttgcctatat
    46741 gcgtggtcgg accttggatg atgcctttgt cattctcgat gaggcgcaaa atacgaccat
    46801 catgcagatg aagatgttct tgactcgttt aggttttcat tctaagatga ttgtcaatgg
    46861 agatattagt cagattgatc tgccacgtaa tgtcaagtcc ggtttgattg atgcccaaga
    46921 aaagctcaag aacatttacc aaattgactt tgttcatttt tcagctaagg atgtggttcg
    46981 ccatccagtt gtcgctcaga ttatccgagc ttatgaacca gctccagtta aaaaagaaga
    47041 gagtgaagaa ttagagtctc aacctctgtc tgaaggatag ttcttttgta cttaaagtta
    47101 tctcaatgct aagtataaat ttgcttttta aatgttttat tcaatatcct tatattagat
    47161 tagaaacgtt tcaagcggag gaaacgtatg gaatcaatat ttgtgaaatt tgcccagtat
    47221 ccgtctatag aaacggagcg tttattgctt agacctgtaa ctttggatga tgcggaagca
    47281 atgtttgact atgcctcgga caagggtaat acacgttaca cttttccaac caatcaaagc
    47341 ttggaagaaa ccaagaataa cattgctcag ttctatttgg ctaatccctt gggacgttgg
    47401 ggaatagaac taaaaagcaa tggtcagttt attggaacca ttgacttgca caagattgat
    47461 tctgttctta agaaggcagc tattggctac attatcaata aaaagtattg gaatcaagga
    47521 ttaacgacag aagccaatcg tgctgtgatt gagctagctt ttgagaagat agggatgaat
    47581 aagttgactg cccttcacga taaggacaat cctgcgtcag gaaaggtcat ggagaaatca
    47641 ggcatgcgtt tttcccatgc agaaccatat gcttgtatgg accagcatga aaaagatcga
    47701 atcgttacaa gagttcatta tgtcttgacc aaggaagact attttgcaaa taaataagca
    47761 gttgaaaaga aatttttcga ctgttttttc ttcctcttac gaataatcta agagaggaga
    47821 aaatatggaa gcaattatcg agaaaatcaa agagtataaa atcatcgtca tctgtactgg
    47881 tctgggcttg cttgtaggcg gatttttcct gctaaagcca gctccacaaa cacctgtaaa
    47941 ggaaacgaat ttgcaggctg aagttgcagc tgtttccaag gatttggtat ccgaaaagga
    48001 agtgaacaag gaagagaagg aagaaccagt tgaacaagat ctaatcacag tagatgtcaa
    48061 aggtgctgtc aaatcgccag ggatttatga cttgcctgta ggtagtcgag tcaatgatgc
    48121 tgttcagaag gctggtggct tgacagagca agcagacagc aagtcgctca atctagctca
    48181 gaaagttagt gatgaggctc tggtttacgt tcctactaag ggagaagaag cagttagtca
    48241 acagactggt tcggggacag cttcttcaat aagcaaggaa aagaaggtca atctcaacaa
    48301 ggccagtctg gaagaactca agcaggtcaa gggactggga ggaaaacgag ctcaggacat
    48361 tatcgaccat cgtgaggcaa atggcaagtt caagtcagta gacgagctca agaaggtctc
    48421 tggcattggt ggcaaaacaa tagaaaagct taaagactat gttacagtgg attaagaatt
    48481 tctctattcc cctaatttac ctgagttttc tattactttg gctttattac gctattttct
    48541 cagcatctta tcttgctttg ttgggctttg tttttctgct agtctgtctc tttatccaat
    48601 ttccgtggaa atctgctggt aaagttctaa taatttgcgg aatctttgga ttttggtttg
    48661 tttttcaaaa ttggcaacag agtcaagcga gtcaaaatct ggcggattct gttgaaaggg
    48721 tacggatttt gcctgatact attaaggtta atggtgatag tctatccttt cgtggcaagt
    48781 ctaacggtcg tgctttccaa gtctattata aactccagtc cgaggaggag aaagaagcct
    48841 ttcaagcttt aaccgacctg catgagatag gactagaagg gaagctttcg gagccagaag
    48901 ggcagagaaa ttttggtggc tttaattacc aagcctatct gaagactcag ggaatttacc
    48961 agactctcaa tatcaaaaca atccagtcac ttcaaaagat tggcagttgg gatataggag
    49021 aaaacttgtc cagtttacgt cgaaaggctg tggtttggat taagacgcac tttccagacc
    49081 ctatgcgcaa ttacatgaca ggactcttgc tgggacatct ggacaccgac tttgaggaga
    49141 tgaatgagct ttattccagt ctaggaatta tccacctctt tgccctatct ggtatgcagg
    49201 taggtttttt catgaatgga tttaagaaac ttctcttgcg attgggcttg acccaagaaa
    49261 agttgaaatg gctgacttat cccttttccc ttatctatgc gggactaact ggattttcag
    49321 catcggttat tcgcagtctc ttgcaaaagc tactggctca acatggggtt aagggcttgg
    49381 ataattttgc cttgacggtg cttgtcctct ttattgtcat gccaaacttt ttcttgacag
    49441 caggaggagt cttgtcctgc gcttatgctt ttatcctgac catgaccagc aaagaagggg
    49501 aggggctcaa ggctgttact agtgaaagtc tagtcatctc cttgggcata ttgcccattc
    49561 tatccttcta ttttgcggaa tttcaacctt ggtctatcct tttgaccttt gtcttttcct
    49621 ttctatttga cttgaccttc ttaccgctct tgtctatttt atttgtcctt tcctttctct
    49681 atccagtcat tcagctgaac tttatctttg aatggttgga gggcattatt cgcttggtgt
    49741 cacaggtgac aagtagacct ctggtctttg gacaacccaa tgcatggttt ttaatcctat
    49801 tgttaatttc cttggctttg gtctatgatt tgagaaaaaa cattaaaaag ctaacggtat
    49861 tgtgcttatt gattacaggg ctctttctcc tgaccaagca tccactggaa aatgaaatca
    49921 ccatgctgga tgtggggcaa ggagaaagta ttttcctacg ggatgtaact gggaaaacca
    49981 ttctcataga tgtaggtggt aaggcagaat cttataagaa aatcgaaaaa tggcaagaaa
    50041 agatgacgac cagcaatgcc cagcgaacct tgattcccta tctcaaaagt cgaggagtag
    50101 ctaagattga ccagctaatt ttgactaaca cggacaagga gaatgttgga gatttgtcag
    50161 aggtgaccaa ggctttccat gtaggggaga ttctagtatc aaaagacagt ctgaaacaga
    50221 aggaatttgt ggcagaacta cagacgactc aaacaaaggt gcgtagtatg acagtagggg
    50281 agaacttgcc catttttgga agtcagttag aagttctatc tccaaggaaa atgggagatg
    50341 gaggacacga tgacacccta gttctgtatg ggaaattctt ggataagcaa tttctcttca
    50401 cggaaaattt ggaggagaaa ggagagaagg acttgctgaa gcactatcca gacttgaaag
    50461 taaatgtttt gaaagctagc caacatggca ataaaaaatc atcaagtcca gcctttctag
    50521 aaaaactcaa accagagctt actcttatct cagttggaaa gagcaatcga atgaaactcc
    50581 cccatcagga aacattgaca cgactggaag gtatcaatag caaagtttat cgaactgacc
    50641 agcaaggagc tatacgtttt aaggggttgg atagttggaa aatcgaaagt gttcgatagg
    50701 aaggataaat gttgtagatt agtgaaataa actaaaaatt tgttgcataa taatgataaa
    50761 aatggtataa tgaaaacgta ttcaatattg aggatataaa atcattaaaa atcagcaaaa
    50821 gttgttttat tagttagttt ataatctatt ggtcttcttc agtccagtgt atctgctgtg
    50881 acagccacta aaagttacaa gtatgattgg aatacggttt tggaatatag taccaactat
    50941 cacgaccatc agtatgcttg gattccggaa tggtctcgtt attacagcta ttctgagtat
    51001 aaagttggcg gaggctggaa ctacgctcgt tatgaggtca taaactacta tactggaggt
    51061 tattaatcct taaagagtga gaaaaggagg gctggatatg ttaaatctta ctcatgttac
    51121 cttaaaaacg cgacaagtca tcttgcaaga tgcggatttt acctttaaaa agggtaggat
    51181 ttatggcctt cttgctatca atggctcggg aaagacgaca ctattccgag ctatgagcaa
    51241 gttgcttccc cttagtagtg gacacatcgc agttcctcct tctttgtttt attatgagag
    51301 cgttgaatgg ctggatggaa acttaagtgg gatggactac cttcgtctca taaaaaacat
    51361 ctggaagtca gacctaaact tgagagatga aatcgcctac tgggaaatgg ctgactatat
    51421 cagtcttccc atccgcaagt attccttagg gatgaagcaa cgcttggtga ttgctatgta
    51481 ttttctcagt caggccaaat gctggctcat ggatgagatt acaaatggct tagacgagta
    51541 ttatcgacag aagttttttg ataggctagc acaaatcgat agacaagaac agctggttct
    51601 tttaagttcc cactataagg aagagttggt tgatatctgc gatagagtag taaccattca
    51661 tcaggggcag atagaagagg tttagtttat gaaagatgtt agtctatttt tattgaaaaa
    51721 agttttcaaa agtcgtttaa actggattat cttactttta tttgcatctg tactcggtgt
    51781 taccttttat ttaaatagtc agactgcaaa ctcacacagc ttggagagca ggttggaaag
    51841 tcgcattgca gccaacgaga gggctatcaa tgaaaatgaa gagaaactct cccaaatgtc
    51901 tgataccagc tcggaggaat accagtttgc taaaaataat ttagacgtgc aaaaaaatct
    51961 tttgacgcga aagacagaaa ttctaacttt actaaaagaa gggcgctgga aagaagccta
    52021 ctatctgcag tggcaagatg aagagaagaa ttatgaattt gtatcaaatg acccgactgc
    52081 tagctctggc ttaaaaatgg gggttgaccg cgaacggaag atttaccaag ccctgtatcc
    52141 cttgaacata aaagcacata ctttggagtt tccgacccac gggattgatc agattgtctg
    52201 gattttagag gttatcatcc caagcttgtt tgtggttgcg attattttta tgctaacaca
    52261 actatttgca gaaagatatc aaaatcatct ggacacagct cacttatatc ctgtttcaaa
    52321 agtgacattt gcaatatcct ctcttggagt tggagtggga tatgtaactg tgctgtttat
    52381 cggaatctgt ggcttttctt ttctagtggg aagtctgata agtggttttg gacagttaga
    52441 ttatccctac ccaatttata gcttagtgaa tcaagaagta actattggga aaatacaaga
    52501 tgtattattt cctggcttgc tcttagcttt cttagccttt atcgtcattg tggaagttgt
    52561 gtacttgatt gcttactttt tcaagcaaaa aatgcctgtc ctctttcttt cactcattgg
    52621 gattgttggt ttattgtttg gcatccaaac cattcagcct cttcaaagga ttgcacatct
    52681 gattcccttt acttacttgc gttcagtgga gattttatct ggaagattac ctaagcaaat
    52741 tgataatgtc aatctaaatt ggagcatggg gatggtcttg cttccttgcc tgattatcct
    52801 tttgttagtg gggattctat ttatcgaaag ctggggaagt tcacgtaaaa aggaagtttt
    52861 taaagtttag ttttcctata gggaagctaa agaaaaacta acatagggag agaatcaact
    52921 tggttctctc tttttgattc gaaaaccaaa ccaaaataca aacacaaact tttcaaaaaa
    52981 taacttttta tcttgacaag agctagaaaa cttggtatca tataaaagtt gagaaaagca
    53041 gaagtgagag cttctcgcct tgtgacatta agttgcctgg ccctacggat gaaaagtttc
    53101 gaagaaacgc tatcataacg tgcgggcttg tatatttaca agtccgctat tgtttttctc
    53161 taataaaaca aaagaggtga aaaccatagc aaagcaagac ttattcatca atgatgagat
    53221 tcgtgtacgt gaagttcgct tgattggtct tgaaggagaa cagctaggta tcaagccact
    53281 cagtgaagcg caagctttgg ctgataacgc taatgttgac ctagtattga ttcaacccca
    53341 agccaaaccg cctgttgcaa aaattatgga ctacggtaag ttcaaatttg agtaccagaa
    53401 gaagcaaaaa gaacaacgta aaaaacaaag cgttgttact gtgaaagaag ttcgtctaag
    53461 tccaacaatt gacaagggtg actttgatac aaaacttcgt aatgcacgta agttccttga
    53521 aaaaggaaat aaagttaagg tatctattcg ctttaagggt cgtatgatta cccataaaga
    53581 gattggtgca aaagttttag ccgagtttgc tgaagcaact caagatattg ccatcatcga
    53641 acaacgtgct aaaatggatg gacgtcaaat gttcatgcaa ttggcgccag cgactgacaa
    53701 aaaataattg tcagaaagtt aaataaagga gaaaaaatca tgccaaaaca aaaaacacac
    53761 cgcgcatcag ctaaacgttt caaacgtaca ggttctggtg gacttaaacg tttccgtgct
    53821 tacacttctc accgtttcca cggaaaaact aagaaacaac gtcgtcatct tcgtaaagca
    53881 tctatggtgc attcaggaga ttacaaacgt atcaaagcaa tgcttactcg cttgaaataa
    53941 tagcttgact gtaagtaaac aattctagga aatatttgga ggaaataaaa catggcacgt
    54001 gttaaaggtg gcgttgtatc acgcaaacgt cgtaaacgta ttcttaaatt agcaaaaggt
    54061 tactatggag ctaaacacat cttgttccgt actgcaaaag aacaagtaat gaactcttac
    54121 tactatgcat accgtgaccg tcgtcagaaa aaacgtgact tccgcaaatt gtggattact
    54181 cgtatcaatg cggcagctcg tatgaacgga ctttcatact cacaattgat gcatggtttg
    54241 aaattggctg agattgaagt taaccgtaaa atgcttgctg acttggctgt taacgatgca
    54301 gtagctttca cagctcttgc agatgcagct aaagcaaaac ttggtaaata ataactgatg
    54361 agactggaac aggattgtcc agtcttttta aaaataaagg agaaagatat ggcttcaaaa
    54421 atgctacaca cttgcttacg agtagaaaat cttgaaaaat caatcgcatt ttatcaagat
    54481 gcttttggtt ttaaagaatt gcgtcgcaga gattttccag accatgcctt cacgattgtc
    54541 tatctaggtc ttgagggtga tgattatgag ttggagttga cttataacta cgatcacggt
    54601 ccgtatgtgg ttggtgatgg gtttgcccat atcgccctca gtacacctga tcttgaggca
    54661 cttcatcaag aacacagtgc aaaaggctat gaagtgactg agccaaatgg tctaccagga
    54721 actacaccaa actattactt tgttaaagac cctgatggat ataaggtcga agtcattcgt
    54781 gaaaaataat ttcgtgcaag ttaagtagaa tattcgtttt ctacttgact ttttttagct
    54841 gaaagagtat actaataaaa attcaacctt taaggggagt ccagagagac tcacaaggtg
    54901 tcagataaaa gaatagtgca attttctaga ggagaccttt tgagtgtgct ctcttgtgtt
    54961 gtacgatttt aactgaggcc ttgcactagc aaggtctttt ctttatctgg tccccttaaa
    55021 atttaaggag gaaaagttat gaatctcaca tgtaagaagc gtttgggtgt cattcggttg
    55081 gaaaccatga aggtggttgc acaagaggaa atcgcgccag caatctttga attagtccta
    55141 gaaggagaaa tggttgaagc catgcgagca ggccaatttc ttcatctgcg tgtaccagac
    55201 gatgcccatc tcttacgtcg tcctatttca atttcgtcta ttgacaaggc aaacaagcag
    55261 tgtcacctca tttatcggat tgagggagct gggactgcaa ttttttcaac cttaagtcag
    55321 ggagacactc ttgatgtgat ggggcctcag ggaaatggtt ttgacttgtc tgaccttgat
    55381 gagcagaatc aggttctcct tgttggtggt gggattggtg ttccaccctt gcttgaggtg
    55441 gccaaggaat tgcatgaacg tggagtgaaa gtagtgacag tcctcggttt tgctaataag
    55501 gatgctgtta ttttgaaaac ggaattggct cagtatggtc aggtctttgt aacgacagat
    55561 gatggttctt atggcatcaa gggaaatgtt tccgttgtta tcaatgattt agatagtcag
    55621 tttgatgctg tttactcgtg tggggctcca ggaatgatga agtatatcaa tcaaaccttt
    55681 gatgatcacc caagagccta tttatctctg gaatctcgta tggcttgtgg gatgggagct
    55741 tgctatgcct gtgttctaaa agtaccagaa agcgagacgg tcagccaacg cgtctgtgaa
    55801 gatggtcctg ttttccgcac aggaacagtt gtattataag gagaaaatta tgactacaaa
    55861 tcgattacaa gtgtctctac ctggtttgga tttgaaaaat ccgattattc cagcatcagg
    55921 ctgttttggc tttggacaag agtatgccaa gtactatgat ttaaaccttt taggttctat
    55981 tatgatcaag gcgacaaccc ttgaaccacg ttttgggaac ccaactccaa gagtagcaga
    56041 gacgcctgct ggtatgctca atgcaattgg cttgcaaaat cctggtttag aggttgtttt
    56101 ggctgaaaag ctaccttggc tggaaagaga atatccaaat cttcctatta ttgccaatgt
    56161 agctggtttt tcaaaacaag agtatgcagc tgtttctcat gggatttcca aggcaactaa
    56221 tgtaaaagct atcgagctca atatttcttg tcccaatgtt gaccactgta atcatggact
    56281 tttgattggt caagatccag atttggctta tgatgtggtg aaagcagctg tggaagcctc
    56341 agaagtgcca gtttatgtca aattaacccc gagtgtgacc gatatcgtta ctgtcgcaaa
    56401 agctgcagaa gatgcgggag caagtggctt gaccatgatc aatactctgg ttggaatgcg
    56461 ctttgacctc aaaaccagaa aaccaatctt ggccaatgga acaggtggaa tgtcaggtcc
    56521 agcagtcttt ccagtagccc tcaaactcat ccgccaagta gcccaaacaa cagacctgcc
    56581 tatcattgga atggggggag tggattcggc tgaagctgcc ctagaaatgt atctggctgg
    56641 ggcatctgct atcggagttg gaacagctaa ctttaccaat ccttatgcct gccctgacat
    56701 catcgaaaat ttaccaaaag tcatggataa atacggtatt agcagtctgg aagaactccg
    56761 tcaggaagta aaagagtctc tgaggtaaac tgcaatcaat ctgttcttga ttttttatta
    56821 gtttgtaata tgaatttagg agaattttgg tacaataaaa taaataagaa cagaggaaga
    56881 aggttaatga agaaagtaag atttattttt ttagctctgc tatttttctt agctagtcca
    56941 gagggtgcaa tggctagtga tggtacttgg caaggaaaac agtatctgaa agaagatggc
    57001 agtcaagcag cgaatgagtg gatttttgat actcattatc aatcttggtt ctatataaaa
    57061 gcagatgcta actatgctga aaatgaatgg ctaaagcaag gtgacgacta tttttacctc
    57121 aaatctggtg gctatatggc caaatcagaa tgggtagaag acaagggagc cttttattat
    57181 cttgaccaag atggaaagat gaaaagaaat gcttgggtag gaacttccta tgttggtgca
    57241 acaggtgcca aagtaataga agactggatc tatgattctc aatacgatgc ttggttttat
    57301 atcaaagcag atggacagca cgcagagaaa gaatggctcc aaattaaagg gaaggactat
    57361 tatttcaaat ccggtggtta tctactgaca agtcagtgga ttaatcaagc ttatgtgaat
    57421 gctagtggtg ccaaagtaca gcaaggttgg ctttttgaca aacaatacca atcttggttt
    57481 tacatcaaag aaaatggaaa ctatgctgat aaagaatgga ttttcgagaa tggtcactat
    57541 tattatctaa aatccggtgg ctacatggca gccaatgaat ggatttggga taaggaatct
    57601 tggttttatc tcaaatttga tgggaaaata gctgaaaaag aatgggtcta cgattctcat
    57661 agtcaagctt ggtactactt caaatccggt ggctacatgg cagccaatga atggatttgg
    57721 gataaggaat cttggtttta cctcaagttt gatggcaaaa tggctgaaaa agaatgggtc
    57781 tacgattctc atagtcaagc ctggtactac ttcaaatccg gtggttacat gacagccaat
    57841 gaatggattt gggataagga atcttggttt tatctcaaat ctgatgggaa aatagctgaa
    57901 aaagaatggg tctacgattc tcatagtcaa gcttggtact acttcaaatc cggtggttac
    57961 atgacagcca atgaatggat ttgggataag gaatcttggt tttacctcaa gtctgatggc
    58021 aaaatggctg aaaaagaatg ggtctacgat tctcatagtc aagcctggta ctacttcaaa
    58081 tctggtggct acatggcgaa aaatgagaca gtagatggtt atcagcttgg aagcgatggt
    58141 aaatggcttg gaggaaaagc tacaaataaa aatgctgctt actatcaagt agtgcctgtc
    58201 acagccaatg tttatgattc agatggtgaa aagctttcct atatatcgca aggtagtgtc
    58261 gtatggctag ataaggatag aaaaagtgat gacaagcgct tggctattac tatttctggt
    58321 ttgtcaggct atatgaaaac agaagattta caagcgctag atgctagtaa ggactttatc
    58381 ccttattatg agagtgatgg ccaccgtttt tatcactatg tggctcagaa tgctagtatc
    58441 ccagtagctt ctcatctttc tgatatggaa gtaggcaaga aatattattc ggcagatggc
    58501 ctgtattttg atggttttaa gcttgagaat cccttccttt tcaaagattt aacagaggct
    58561 acaaactaca gtgctgaaga attggataag gtatttagtt tgctaaacat taataatagc
    58621 cttttggaga acaagggcgc tacttttaag gaagccgaag aacattacca tatcaatgcc
    58681 ctttatctcc ttgcccatag tgccctagaa agtaactggg gaagaagtaa aattgccaaa
    58741 gataagaata atttctttgg cattacagcc tatgatacga ccccttacct ttctgccaag
    58801 acatttgatg atgtggataa gggaatttta ggtgcaacca agtggattaa ggaaaattat
    58861 atcgataggg gaagaacttt ccttggaaac aaggcttctg gtatgaatgt ggaatatgct
    58921 tcagaccctt attggggcga aaaaattgct agtgtgatga tgaaaatcaa tgagaagcta
    58981 ggtggcaaag attagtacta taagtgaata tgatttgagt gaatagtaag ttaaaaatcc
    59041 tgatttcaag taaaatcagg attttttcat ggatgcaatt tttttggagt ctggtgtgac
    59101 gcggagggtc ttttgtcctg tgtaagtgac aaagccgggt tttccaccag ttggtttatt
    59161 gagttttttg acttcaatca tatctacctg caccagattc gacaggcgcc cttgagagaa
    59221 gtaggcagct aactctgctg cgtctgtctt gactgcatca gatgggtcaa gatttcctga
    59281 gatgacaaca tggcttccag gaatgtcctt agcatggaac caaagttcct ccttgcgggc
    59341 cattttaaag gtcaattcct cattttgaag attgtttcgt ccgacataga tgatggtttt
    59401 gccatcgctt gctagatatt gttctagttt tttgcgtttc tggattttct cccgttgtct
    59461 tctgcggata aaacctgttt gaatcaattc ttcgcggatt tcagcgattt cttccagtcc
    59521 agcttggttg aggacggttt ctacactttc cagatagaga atagtggctt tggtttcttc
    59581 aatcaaatca gtcaagtatt tgacagcttc tttgagtttc tgataccgtt taaaatagcg
    59641 ttgggcattc tggttgggag tcagagcctt atcaagcgca atcatgatag gttggttggt
    59701 atagtagttg tctaggataa cctggtcttg gtcgttaggc acttggtgta ggaaggttgt
    59761 cagcaattct cctttttgac gaaattcttc agcgttgtct gtcgccagta actctttttc
    59821 ctgttttttg agtttgtgtc ggtttttctg aagttcattt tcaacacgac gaatcagttc
    59881 actggcctgc tgtttgacgc ggtcgcgctc agccttatcc ttatagtagg tgtccaacaa
    59941 atcagaaaga tttgcaaaag gctctcccac ctgatttgca aaaggaactg gactgaagga
    60001 agtctcagtc aagcatggct tggtttcctg attgaaaaaa tttcggaaag cggaaagttt
    60061 ttcactaacc agtatccttt ccaattcatt tgccgtatcg cgtcccagac cttgaaagag
    60121 gctttgaaga ttttttgctg ttagttcttg ggtttgcagg atttcaaaga gcttttcatc
    60181 cttgatagta aaaggattga gagattctgt acttggcgga gcgatatagg tcgatcctgg
    60241 aagtaaggtg cggtagctat tttgtgaaaa gccgacgtgt ttgataactt cgaggatttt
    60301 atgactgctt ttatcgacca gtagaatatt actgtgtttc cccataattt cgataatcaa
    60361 ggtagcctgg atatggtctc caatctcgtt tttattggaa actgtaattt ccacaatacg
    60421 gtcattttcc acttgctcaa tcgactcaat cagggccccc tgcaaatact ttctcaaaac
    60481 catgataaag gtagaaggtt gggctggatt ttcaaaagtc gtttgggtca gctgaatgcg
    60541 tccaaaaact ggatgggcag aaaggagcag gcgatggctt tggcgattgc tgcggatttg
    60601 caagaccaac tcttgttcaa aaggctgatt gattttctgg atgcgaccat tcactaattc
    60661 gcttcgcaat tcctcaacta tgtggtgtaa aaaaaatccg tcaaatgaca tcgttctctc
    60721 cttgtgattg tattccatag tattatatca aaaaggtaga ataaaatcat ggaaatgtgg
    60781 tataataaag ccaagtaaag agaaacgaga agcacatgta tattgaaatg gtagatgaaa
    60841 ctggtcaagt ttcaaaagaa atgttgcaac aaacccaaga aattttggaa tttgcagccc
    60901 aaaaattagg aaaagaagac aaggagatgg cagtcacttt tgtgaccaat gagcgtagtc
    60961 atgaacttaa tctggagtac cgtgacaccg accgtccgac agatgtcatc agccttgagt
    61021 ataaaccaga attggaaatt gcctttgacg aagaggattt gcttgaaaat ccagaattgg
    61081 cagagatgat gtctgagttt gatgcctata ttggggaatt gttcatctct atcgataagg
    61141 ctcatgagca ggccgaagaa tatggtcaca gctttgagcg tgagatgggc ttcttggcag
    61201 tacacggctt tttacatatt aacggctatg atcactatac tccggaagaa gaagcggaga
    61261 tgttcggttt acaagaagaa attttgacag cctatggact cacaagacaa taaacgaaaa
    61321 tggaaaaatc gtgacttgat atccagttta gaatttgcca tcacagggat ttttactgct
    61381 atcaaggaag aacgaaatat gcgaaaacat gcagtgacgg ctctagtggt catccttgca
    61441 ggttttgttt ttcaggtgtc acgaatcgaa tggctctttc ttctattgag tattttcttg
    61501 gtagtagcct ttgagattat caactctgct attgaaaatg tggtggattt ggccagtcac
    61561 tatcactttt ccatgctggc taaaaatgcc aaggatatgg cggccggcgc ggtattagtg
    61621 gtttctcttt tcgcagcctt aacaggcgca ttgatttttc tcccacgaat ctgggattta
    61681 ttattttaaa cagtaagagg aaattatgac ttttaaatca ggctttgtag ccattttagg
    61741 acgtcccaat gttgggaagt caaccttttt aaatcacgtt atggggcaaa agattgccat
    61801 catgagtgac aaggcgcaga caacgcgcaa taaaatcatg ggaatttaca cgactgataa
    61861 ggagcaaatt gtctttatcg acacaccagg gattcacaaa cctaaaacag ctctcggaga
    61921 tttcatggtt gagtctgcct acagtaccct tcgcgaagtg gacaccgttc ttttcatggt
    61981 gcctgctgat gaagcgcgtg gtaaggggga cgatatgatt atcgagcgtc tcaaggctgc
    62041 caaggttcct gtgattttgg tggtgaataa aatcgataag gtccatccag accagctctt
    62101 gtctcagatt gatgacttcc gtaatcaaat ggactttaag gaaattgttc caatctcagc
    62161 ccttcaggga aataacgtgt ctcgtctagt ggatattttg agtgaaaatc tggatgaagg
    62221 tttccaatat ttcccgtctg atcaaatcac agaccatcca gaacgtttct tagtttcaga
    62281 aatggttcgc gagaaagtct tgcacctaac tcgtgaagag attccgcatt ctgtagcagt
    62341 agttgttgac tctatgaaac gagacgaaga gacagacaag gttcacatcc gtgcaaccat
    62401 catggtcgag cgcgatagcc aaaaagggat tatcatcggt aaaggtggcg ctatgcttaa
    62461 gaaaatcggt agcatggccc gtcgtgatat cgaactcatg ctaggagaca aggtcttcct
    62521 agaaacctgg gtcaaggtca agaaaaactg gcgcgataaa aagctagatt tggctgactt
    62581 tggctataat gaaaaagaat actaagtaga ggtgggctca tgcctgcttc ttgttttaca
    62641 gaaggaggac ttatgcctga attacctgag gttgaaaccg tttgtcgtgg cttagaaaaa
    62701 ttgattatag gaaagaagat ttcgagtata gaaattcgct accccaagat gattaagacg
    62761 gatttggaag agtttcaaag ggaattgcct agtcagatta tcgagtcaat gggacgtcgt
    62821 ggaaaatatt tgctttttta tctgacagac aaggtcttga tttcccattt gcggatggag
    62881 ggcaagtatt tttactatcc agaccaagga cctgaacgca agcatgccca tgttttcttt
    62941 cattttgaag atggtggcac gcttgtttat gaggatgttc gcaagtttgg aaccatggaa
    63001 ctcttggtgc ctgacctttt agacgcctac tttatttcta aaaaattagg tcctgaacca
    63061 agcgaacaag actttgattt acaggtcttt caatctgccc ttgccaagtc caaaaagcct
    63121 atcaaatccc atctcctaga ccagaccttg gtagctggac ttggcaatat ctatgtggat
    63181 gaggttctct ggcgagctca ggttcatcca gctagatctt cccagacttt gacagcagaa
    63241 gaagcgacag ctattcatga ccaaaccatt gctgttttga gccaggctgt tgaaaaaggc
    63301 ggttccacca ttcggaccta taccaatgcc tttggggaag atggaagcat gcaggatttt
    63361 catcaggtct atgataagac tggtcaagaa tgtgtacgct gtggtaccat cattgagaaa
    63421 attcaactag gcggacgagg cacccacttt tgtccaaact gtcaaaggag ggactgatga
    63481 gaaaaatcat cggaatcact gggggaattg cctctggtaa gtcaactgtg acaaattttc
    63541 taagacagca aggctttcaa gtagtggatg ccgacgcagt cgtccaccaa ctacagaaac
    63601 ctggtggtcg tctgtttgag gctctagtac agcactttgg gcaagaaatc attcttgaaa
    63661 acggagaact caatcgccct ctcctagcta gtctcatctt ttcaaatcct gaagagcaaa
    63721 aatggtctaa gcaaattcaa ggggagatta tccgtgagga actggctact ttgagagaac
    63781 agttggctca gacagaagag attttcttca tggatattcc cctacttttt gagcaggact
    63841 acagcgattg gtttgctgag acttggttgg tctatgtgga ccgagatgcc caagtagaac
    63901 gcttaatgaa aagggaccag ttgtccaaag atgaagctga gtctcgtctg gcagcccagt
    63961 ggcctttaga aaaaaagaaa gatttggcca gccaggttct tgataataat ggcaatcaga
    64021 accagcttct taatcaagtg catatccttc ttgagggagg taggcaagat gacagagatt
    64081 aactggaagg ataatctgcg tattgcctgg tttggtaatt ttctgacagg agccagtatt
    64141 tctttggttg taccttttat gcccatcttc gtggaaaatc taggtgtagg gagtcagcaa
    64201 gtcgcttttt atgcaggctt agcaatttct gtctctgcta tttccgcggc gctcttttct
    64261 cctatttggg gtattcttgc tgacaaatac ggccgaaaac ccatgatgat tcgggcaggt
    64321 cttgctatga ctatcactat gggaggcttg gcctttgtcc caaatatcta ttggttaatc
    64381 tttcttcgtt tactaaacgg tgtatttgca ggttttgttc ctaatgcaac ggcactgata
    64441 gccagtcagg ttccaaagga gaaatcaggc tctgccttag gtactttgtc tacaggcgta
    64501 gttgcaggta ctctaactgg tccctttatt ggtggcttta tcgcagaatt atttggcatt
    64561 cgtacagttt tcttactggt tggtagtttt ctatttttag ctgctatttt gactatttgc
    64621 tttatcaagg aagattttca accagtagcc aaggaaaagg ctattccaac aaaggaatta
    64681 tttacctcgg ttaaatatcc ctatcttttg ctcaatctct ttttaaccag ttttgtcatc
    64741 caattttcag ctcaatcgat cggccctatt ttggctcttt atgtacgcga cttagggcag
    64801 acagagaatc ttctttttgt ctctggtttg attgtgtcca gtatgggctt ttccagtata
    64861 atgagtgcag gagtcatggg caagctaggt gacaaggtgg gcaatcatcg tctcttggtt
    64921 gtcgcccagt tttattcagt catcatctat ctcctctgtg ccaatgcctc tagccccctt
    64981 caactaggac tctatcgttt cctctttggc ttgggaaccg gtgccttgat tcccggggtt
    65041 aatgccctac tcagcaaaat gactcccaaa gccggcattt cgagggtctt tgccttcaat
    65101 caggtattct tttatctggg aggtgttgtt ggtcccatgg caggttctgc agtagcaggt
    65161 caatttggct accatgctgt cttttatgcg acaagccttt gtgttgcctt tagttgtctc
    65221 tttaacctga ttcaatttcg aacattatta aaagtaaagg aaatctagtg cgagtaaaaa
    65281 ttaatctcaa atgctcctct tgtgacagta tcaattacct aaccagtaaa aattcaaaaa
    65341 cccatccaga caagattgag gttttaaagt attgtcccaa ggaaagaaaa gtaaccctac
    65401 atcttgaatc taagtagatt ttatggtaaa ataataggga ttttaaggag tttgatatgt
    65461 ataacctatt attaaccatt ttattagtat tatctgttgt gattgtgatt gcaattttca
    65521 tgcaaccaac caaaaaccaa tccagcaatg tatttgatgc cagttcaggt gatttgtttg
    65581 aacgcagtaa agctcgcggt tttgaagctg taatgcagcg tttgacaggg attttagtct
    65641 ttttctggct agccattgcc ttagcattga cggtattatc aagtagataa gaaaataatg
    65701 ggcaggacta ggtctttgcc tctttttatt tttaaaggat gtttgagaag gttttacagt
    65761 aaaagaaaat taaaaaatct agaaagaaaa tatgaaagat agaataaaag aatatttaca
    65821 agacaaggga aaggtgactg ttaatgattt ggctcaggct ttgggaaaag acagttccaa
    65881 ggattttcgt gagttgatta aaaccttgtc cttaatggaa agaaagcacc agattcgctt
    65941 tgaagaagat ggcagtctga ccttggaagc caagaaaaaa catgagatta ccctcaaggg
    66001 gatttttcat gcccataaaa atggttttgg ttttgtcagc ctagaagggg aagaggacga
    66061 cctttttgta gggaaaaatg atgtcaacta tgctattgat ggtgataccg tcgaggtagt
    66121 gattaagaaa gtcgctgacc gcaataaggg aacagcagca gaagccaaaa ttattgatat
    66181 cctagaacac agtttgacaa cagttgtcgg gcaaatcgtt ctggatcagg aaaagcctaa
    66241 gtatgctggc tatattcgtt caaaaaatca gaaaatcagt caaccgattt atgttaagaa
    66301 accagcccta aagttagaag gaacagaagt tctcaaggtc tttatcgata aatacccaag
    66361 caagaaacat gatttctttg tcgcgagtgt tctcgatgtg gtgggacact caacggatgt
    66421 cggaattgat gttcttgagg ttttggaatc aatggacatt gtatccgagt ttccagaagc
    66481 tgttgttaag gaagcagaaa gtgtgcctga tgctccgtct caaaaggata tggaaggtcg
    66541 tctggatcta agagatgaaa ttacctttac cattgacggt gcggatgcca aggacttgga
    66601 cgatgcagtg catatcaagg ctctgaaaaa tggcaatctg gagcttgggg ttcacatcgc
    66661 agatgtttct tattatgtga ccgaggggtc tgcccttgac aaggaagccc ttaaccgtgc
    66721 gacttctgtt tacgtgacag accgagtggt gccaatgctt ccagaacgac tatcaaatgg
    66781 catctgctct ctcaatcccc aagttgaccg cctgacccag tctgctatta tggagattga
    66841 taaacatggt cgtgtggtca actataccat tacacaaaca gttatcaaga ccagttttcg
    66901 tatgacctat agcgatgtca atgatatcct agctggcgat gaagaaaaga gaaaaaaata
    66961 tcataaaatt gtaccaagta tcgaactcat ggccaagctt catgaaactt tagaaaacat
    67021 gcgtgtgaaa cgtggagctc tcaattttga taccaatgaa gcgaagattt tagtggataa
    67081 acaaggtaag cctgttgata tcgttcttcg gcagcgtggt attgccgagc ggattattga
    67141 gtcttttatg ttgatggcta atgaaacagt tgccgaacat ttcagcaagt tggatttgcc
    67201 ttttatctat cgaattcacg aggagcctaa ggctgaaaag gttcagaagt ttattgatta
    67261 tgcttcgagt tttggcttgt gcatttatgg gactgccagt gagattagtc aggaggcact
    67321 tcaagacatc atgcgtgctg ttgagggaga accttatgca gatgtattgt ccatgatgct
    67381 tcttcgctct atgcagcagg ctcgttattc ggagcacaat cacggccact atggactagc
    67441 tgctgactat tatactcact ttaccagtcc aattcgtcgt tatccagacc ttcttgttca
    67501 ccgtatgatt cgagattacg gctgttctaa ggaaatagca gagcattttg aacaagtgat
    67561 tccagagatt gcgacccagt cttccaaccg tgaacgtcgt gccatagaag ctgagcgtga
    67621 agtcgaagcc atgaaaaagg ctgagtatat ggaagaatac gtgggtgaag agtatgatgc
    67681 agttgtatca agtattgtca aattcggtct ctttgtcgaa ttgccaaaca cagttgaagg
    67741 cttgattcac atcactaatc tacctgaatt ttatcatttc aatgagcgtg atttgactct
    67801 tcgtggagaa aaatcaggta tcactttccg agtgggtcag cagatccgta tccgtgttga
    67861 aagagcggat aaaatgactg gagagattga tttttcattc gtacctagtg agtttgatgt
    67921 gattgaaaaa ggcttgaaac agtctagtcg tagtggcaga gggcgtggtt caaatcgtcg
    67981 ttcggataag aaggaagaca agagaaaatt aggacgctca aatgataagc gtaagcattc
    68041 acaaaaagac aagaagaaaa aaggaaagaa acctttttac aaggaagtag ctaagaaagg
    68101 agccaagcat ggcaaagggc gagggaaagg tcgtcgcaca aaataaaaag gcacgccacg
    68161 actatacaat cgtagatacg ctagaggcag ggatggtcct gactggaact gaaatcaaga
    68221 gtgtacgagc tgctcgaatt aatctcaagg atggctttgc tcaagtgaaa aatggagaag
    68281 tttggctgag caatgttcat atcgcgcctt acgaagaggg caatatctgg aaccaggaac
    68341 cagaacgtcg tcgtaaactc ctgctccata aaaagcaaat tcaaaaattg gaacaagaga
    68401 ccaaagggac aggaatgacc ttagttcccc ttaaggtcta tataaaagat ggctacgcta
    68461 agcttctttt aggacttgcc aaagggaagc atgactatga caaacgggag tctatcaaac
    68521 gtcgtgagca aaatcgagat atcgcgcgtg tgatgaaagc tgttaatcag cgataaaaag
    68581 aggaattgaa aatggaaaaa ttagttgcct ataaacgcat gcctttgtgg aataaacaaa
    68641 caatgcctga agctgttcag caaaagcaca atacaaaagt tgggacttgg gggaaaatta
    68701 ctgtcttgaa gggagctctc aagtttattg aattgacaga agaaggggaa gttctagctg
    68761 aacacctctt tgaagcaggg gcagacaatc caatggccca acctcaagcc tggcactgag
    68821 tggaagctgc cacagatgat gtggaatggt acttggaatt ttattgtaaa cctgaggatt
    68881 attttgctaa aaaatacaat accaatcctg ttcattcaga ggtcctagag gccatgcaga
    68941 cagtgaaaca agggaaagct ttggatttgg gttgtggtca ggggcgtaat tctctttttc
    69001 tagcccagca agattttgat gtgacggctg tagatcaaaa tggactggct cttgaaatct
    69061 tgcaaagcat tgtggagcag gaagatttgg acatgcctgt tggcctttac gatatcaatt
    69121 cagctagcat tggacaagaa tatgatttta tcgtttcaac agttgttctc atgtttctac
    69181 aagcggaccg cattccagct attattcaaa atatgcagga gaaaaccagt gttggtggtt
    69241 acaaccttat cgtttgtgcc atggacacgg aggattatcc ttgctcggtt aatttcccat
    69301 tcacctttaa agaaggagaa ctggcagact attacaagga ttgggaattg gttaagtaca
    69361 atgaaaatcc aggccatttg catcgtcgcg atgagaatgg caatcgtatt caactacgct
    69421 ttgcgacctt actagctaag aaaatcaagt aaacacacat gaagattagg aattttcctg
    69481 atcttttttc ttttttacga atgatataga aaaggaggga attcatgttt gttgcgagag
    69541 atgctagggg agaattggta aatgtgttag aggataaact tgagaagcaa gcatacacct
    69601 gcccagcttg tggaggccag ctccatttgc gtcaaggacc aagtgtacgg acgcattttg
    69661 cccataaatc cttaaaagac tgtgattttt tctttgaaaa tgaaagtcca gaacacctgg
    69721 ccaataagga atccctctat cactggttga aaaaagagac aaaggttcaa ttagagtacc
    69781 cgctttcaga acttaaacag attgcggatg tatttgtaaa tggcaatcta gctctagaag
    69841 ttcagtgtag tcccttgcct cagaaagtcc ttaaagagcg aagtgaggga tatcgtagtc
    69901 agggttacca agtactgtgg ttgctgggtc aaaaactgtg gctcaaggag cgtttgactc
    69961 gtctacagca aggttttctt tatttcagtc aaaacatggg cttttatgtt tgggaattag
    70021 acaaggaaaa acaagtttta agactcaaat acctgattta ccaggatctc cgcggtaaac
    70081 tccattatca aatcaaggaa ttttcctatg gtcaaggtag tttattggaa atattgcgtc
    70141 ttccctataa gagacaaaaa atatctcatt ttacagtttc tgaggacaag gacatctgtc
    70201 gctatatccg gcaacaactt tattatcaaa atctcttttg gatgaaagaa caagcagaag
    70261 cctatcaaaa gggagaaaat atcctgactt atggactgaa agaatggtat ccacaaattc
    70321 gaccaatagt gggcaaattt ttccagattg aacaagactt gactagctat tatcagtact
    70381 tttataccta ttaccaaaaa aatcctcaaa atgattggca aaagctttat ccaccagcct
    70441 tttatcagca atatttcttg aaaaatatgg tagaataaaa aggatggagg aatctaatgg
    70501 tattacaaag aaatgaaata aatgaaaaag atacatggga tctatcaacg atctacccaa
    70561 ctgaccaggc ttgggaagaa gccttaaaag atttaacaga acaattggag acagtagccc
    70621 agtatgaagg ccatctcttg gatagtgcgg ataacctact agaaatcact gaattttctc
    70681 ttgaaatgga acgccagatg gagaagcttt acgtttatgc tcatatgaag aatgaccagg
    70741 atacacgtga agctaagtat caagagtact atgccaaggc catgacactc tacagccagt
    70801 tagaccaagc cttttcattc tatgatcctg aatttatgga gattagcgaa aagcagtatg
    70861 ctgacttttt agaagctcaa ccaaagctgc aggtttatca acactatttt gacaagctct
    70921 tgcaaggcaa ggatcacgtt ctttcacaac gtgaagaaga attattggct ggagctggag
    70981 aaatctttgg ttcagcaagt gaaaccttcg ctatcttgga caatgcggat attgtgttcc
    71041 cttatgtcct agacgatgat ggtaaagaag ttcagctatc tcatgggact tacacacgtt
    71101 tgatggagtc taaaaaacgt gaggttcgcc gtggtgccta tcaagctctt tatgcgactt
    71161 acgaacaatt ccaacacacc tatgccaaaa ccttgcaaac caatgttaag gtgcaaaatt
    71221 accgtgctaa agttcgtaac tacaagagtg ctcgtcatgc agccctcgca gcgaattttg
    71281 ttccagaaag tgtttatgac aatttggtag cagcagttcg caagcatttg ccactcttac
    71341 atcgctatct tgagcttcgt tcaaaaatct tggggatttc agatctcaag atgtacgatg
    71401 tctacacacc gctttcatct gttgaataca attttaccta ccaagaagcc ttgaaaaaag
    71461 cagaagatgc tttggcagtc ttgggtgagg attacttgag ccgtgtcaaa cgtgccttca
    71521 gcgagcgttg gattgatgtt tacgaaaatc aaggcaagcg ttcaggtgcc tactctggtg
    71581 gttcttacga taccaatgcc tttatgcttc tcaactggca ggacaatctg gacaatctct
    71641 ttactcttgt tcatgaaaca ggtcacagta tgcattcaag ctatactcgt gaaactcagc
    71701 cttatgttta cggagattac tctatctttt tggctgagat tgcctcaact accaatgaaa
    71761 atatcttgac ggagaaatta ttggaagaag tggaagacga cgcaacacgc tttgctattc
    71821 tcaataactt cctagatggt ttccgtggaa cagttttccg ccaaactcaa tttgctgagt
    71881 ttgaacacgc cattcaccaa gcagatcaaa atggggaggt cttgacaagc gatttcctaa
    71941 ataaactcta cgcagacttg aaccaagagt attatggttt gagtaaggaa gacaatcctg
    72001 aaatccaata cgagtgggct cgcattccac acttctacta taactactat gtatatcaat
    72061 attcaactgg ctttgcggcc gcctcagcct tggctgaaaa aattgtccat ggtagtcaag
    72121 aagaccgtga ccgctatatc gactacctca aggcaggtaa gtcggactat ccacttaatg
    72181 tcatgagaaa agctggtgtt gatatggaga aggaagacta cctcaacgat gcctttgcag
    72241 tctttgaacg ccgtttaaat gagtttgaag cccttgttga aaaaatagga ttggcataaa
    72301 atggttgaat cgtatagtaa gaatgctaac cataacatgc gtcgtcctgt cgtcaaagaa
    72361 gaaattgtag acttgatgcg tcagcgtcaa aagcaagtca caggttcctt gaaagaattg
    72421 gaagactttg cccgcaagga aaatattcct attattcccc atgaaacggt tgcttatttc
    72481 cgttttctta tggaaaccat gcagcctaaa aatattctgg aaattgggac ggctatcggt
    72541 ttttcagctc tcttgatggc tgaacatgcg ccaaatgcta agattacaac tattgatcgt
    72601 aatccagaaa tgattggttt tgccaaggaa aattttgccc agtttgacag tcgcaagcaa
    72661 atcactctcc tagagggaga tgcggtggat gtcttatcta cactgacaga gtcttatgat
    72721 ttcgtcttta tggattctgc caagtctaaa tacatcgtct ttctgccaga aatcctcaaa
    72781 catttggaag ttggtggtgt ggttgtcttg gatgatattt ttcaaggtgg tgatgttgcc
    72841 aaggatatta tggaagtccg tcgtggtcag cgaaccattt atcgaggcct tcaaaaatta
    72901 tttgatgcaa ccttagacaa tccagaactc accgcaacat tagtgccttt aggagatggt
    72961 attctcatgc ttcgtaaaaa tgtagcagat gttcaactgt ctgaaagcga atgattttca
    73021 gaaaaattta agaaaaaata gtaaaataga tagagtaaca cttatctcaa aggagtagac
    73081 atgaagaaaa aattattggc aggtgccatc acactattat cagtagcaac tttagcagct
    73141 tgttcgaaag ggtcagaagg ggcagacctt atcagcatga aaggggatgt catcacagaa
    73201 catcaatttt atgagcaagt gaaaagcaac ccttcagccc aacaagtctt gttaaatatg
    73261 accatccaaa aagtttttga aaaacaatat ggctcagagc ttgatgataa agaggttgat
    73321 gatactattg ccgaagaaaa aaaacaatat ggcgaaaact accaacgtgt cttgtcacaa
    73381 gcaggtatga ctcttgaaac acgtaaagct caaattcgta caagtaaatt agttgagttg
    73441 gcagttaaga aggtagcaga agctgaattg acagatgaag cctataagaa agcctttgat
    73501 gagtacactc cagatgtaac ggctcaaatc atccgtctta ataatgaaga taaggccaaa
    73561 gaagttctcg aaaaagccaa ggcagaaggt gctgattttg ctcaattagc caaagataat
    73621 tcaactgatg aaaaaacaaa agaaaatggt ggagaaatta cctttgattc tgcttcaaca
    73681 gaagtacctg agcaagtcaa aaaagccgct ttcgctttag atgtggatgg tgtttctgat
    73741 gtgattacag caactggcac acaagcctac agtagccaat attacattgt aaaactcact
    73801 aagaaaacag aaaaatcatc taatattgat gactacaaag aaaaattaaa aactgttatc
    73861 ttgactcaaa aacaaaatga ttcaacattt gttcaaagca ttatcggaaa agaattgcaa
    73921 gcagccaata tcaaggttaa ggaccaagcc ttccaaaata tctttaccca atatatcggt
    73981 ggtggagatt caagctcaag cagtagtaca tcaaacgaat agtccaaatc aatgagtcag
    74041 ggaaaaaact cgacttcagg aaaaaatgaa gcaaacattc ccacaataaa acgcatagta
    74101 caaggtttgt actgcccccc aaaaaagtta gacaattaat ttatccgaag gatttagttc
    74161 tgtattgcac agagctaagt ccttttagtt ttatcttaat tctcttattg ttgtaataat
    74221 caatatagtc tataatggct tgttccaatt gattaagtga tttaaatgtt tgctcatagc
    74281 cataaaacat ttcggatttt aaaatgccaa agaaagattc catcctaccg ttgtcttggc
    74341 tgtttccttt gcgtgacata gatgcttgaa ttcccttact ctctaggaag cgatgataag
    74401 aatcgtgttg gtattgccag ccttggtcac tatggagaat cgtattctcg tagtgcttct
    74461 ctttgaatgc tgttccaaca
//
LOCUS       DAVLXH010000004        70383 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00028199
            SAMN33607166-rid17955573.denovo.004, whole genome shotgun sequence.
ACCESSION   DAVLXH010000004 DAVLXH010000000
VERSION     DAVLXH010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607166
            Sequence Read Archive: SRR23725544
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 70383)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 70383)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721421.1
            Genome Coverage       :: 115x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:42:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,210
            CDSs (total)                      :: 2,161
            Genes (coding)                    :: 2,023
            CDSs (with protein)               :: 2,023
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 73 of 138
            Pseudo Genes (incomplete)         :: 60 of 138
            Pseudo Genes (internal stop)      :: 40 of 138
            Pseudo Genes (multiple problems)  :: 31 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..70383
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607166-rid17955573.denovo.004"
                     /strain="AUSMDU00028199"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1349"
     gene            <1..110
                     /locus_tag="VYO11_000263"
     CDS             <1..110
                     /locus_tag="VYO11_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000753868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HEV1594884.1"
                     /translation="TVSGQWYYTYNSGDLLVNTTTPDGYRVNANGEWVG"
     gene            complement(590..739)
                     /gene="rpmG"
                     /locus_tag="VYO11_000264"
     CDS             complement(590..739)
                     /gene="rpmG"
                     /locus_tag="VYO11_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001265622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEV1594885.1"
                     /translation="MRVNITLEHKESGERLYLTSKNKRNTPDRLQLKKYSPKLRKHVV
                     FTEVK"
     gene            complement(755..937)
                     /gene="rpmF"
                     /locus_tag="VYO11_000265"
     CDS             complement(755..937)
                     /gene="rpmF"
                     /locus_tag="VYO11_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HEV1594886.1"
                     /translation="MAVPARRTSKAKKNKRRTHYKVTAPSVNFDETTGDYSRSHRVSL
                     KGYYKGRKIAKAASAE"
     gene            complement(1089..1265)
                     /locus_tag="VYO11_000266"
     CDS             complement(1089..1265)
                     /locus_tag="VYO11_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEV1594887.1"
                     /translation="MPLRLSTKLYAALASWAEDDFRSVNGQIEYLLTECVKQRKKDGK
                     YVSETIDEPFEIDI"
     gene            complement(1291..1976)
                     /locus_tag="VYO11_000267"
                     /pseudo
     CDS             complement(1291..1976)
                     /locus_tag="VYO11_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136853.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            2167..4197
                     /locus_tag="VYO11_000268"
     CDS             2167..4197
                     /locus_tag="VYO11_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000460919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HEV1594888.1"
                     /translation="MFDYRALVILMTLMDHCELSLYELSVKVSLPIKEVKEGIDYLVP
                     YLANKGIVLDKKQGRYSLSNRTKQSLTDIIKSDELVLPKSTRLALIYLYTFCRLDFIS
                     NNHYQDFLKVSKNTTLSDIQSLRKIMLDNDLELGYSRAKGYTLHGSEWNKHRLAFQMV
                     SELLESSIGIWGLDYVLSSWGYSLTYDLIDQVVKDYYEKLQLVPIVNQLKVYLFGLVF
                     ILCRYQRDVERVCLSETLVSPVIQDITTILLDTVVDLGIIDTVFSEDDYRYITVLLSS
                     CFEGEVDVAPVYFNQLTEAIISRMEDISLLHFKQREGLRENLRRHLIPAYYRLKFGLP
                     SSNEYVLHVKEHYPDLFELVKDSLMPLMDAIDNPIPDSETAYFVIHFGGYLKKADTLP
                     QKCYKAAIICPNGVSSSLMLKENLLALFPQIEFIGTSKIDDLQVKVSSDYDMVFSTIK
                     VETEKPNYLVSVMMTEEQAIQLVELVLKDFPNLEYGDFEIEQILNIVKRYGIITQELE
                     LRLALKNYLYQKNDRKEIVPVLEQLITKETYQVSSQKLGWKEAIRLAAKPLLDQDKIT
                     ENYPEAMIQKVEEFGPFINLGKGVAIPHARPDEGVNEIGMSMLVLEEPIYLLDNPEQE
                     VRLLICIAAIDNESHLKALSHLTIILRDKNHVQTLISSKNYDDIKMIIKQED"
     gene            4201..4485
                     /locus_tag="VYO11_000269"
     CDS             4201..4485
                     /locus_tag="VYO11_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV1594889.1"
                     /translation="MLKIGTACGSGLGSSFMVQMNIESVLSDLNVSDVEVEHYDLGGA
                     DPNAADIWIVGRDLADSASHLGDVRILNSIIDMDELRELITKLCEEKGLI"
     gene            4498..5844
                     /locus_tag="VYO11_000270"
     CDS             4498..5844
                     /locus_tag="VYO11_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000975284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEV1594890.1"
                     /translation="MMKFILDIVSTPAILVALIAILGLVLQKKKLPDIIKGGIKTFVG
                     FLVVSGGAGIVQNSLNPFGTMFEHAFHLSGVVPNNEAIVAVALTTYGSATAMIMFAGM
                     VFNILIARFTRFKYIFLTGHHTLYMACMIAVILSVAGFTSLPLILLGGLALGIIMSIS
                     PAFVQKYMVQLTGNDKVALGHFSSLGYWLSGFTGSLIGDKSKSTEDIKFPKSLAFLRD
                     STVSITLSMAVIYIIVAIFAGSEYIEKEISSGTSGLVYALQLAGQFAAGVFVILAGVR
                     LILGEIVPAFKGISERLVPNSKPALDCPIVYTYAPNAVLIGFISSFVGGLVSMVIMIA
                     SGTVVILPGVVPHFFCGATAGVIGNASGGVRGATIGAFLQGILISFLPVFLMPVLGGL
                     GFQGSTFSDADFGLSGIILGMLNQFGSQAGIVIGLVLILAVMFGVSFIKKPSAKEE"
     gene            5848..6705
                     /locus_tag="VYO11_000271"
     CDS             5848..6705
                     /locus_tag="VYO11_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HEV1594891.1"
                     /translation="MILSKNREDGLRKFATNIRLNTLRTLNHLGFGHYGGSLSIVEVL
                     AVLYGEIMPMTPEIFAARDRDYFILSKGHGGPALYSTLYLNGFFDKEFLYSLNTNGTK
                     LPSHPDRNLTPGIDMTTGSLGQGISVATGLAYGQRIRKSPFYTYAIVGDGELNEGQCW
                     EAIQFASHQQLSNLIVFVDENKKQLDGFTKDICNPGDFVEKFSAFGFESIRVKGSDIR
                     EIYEGIVQLKQSNNSSPKCIVLDTIKGQGVQELEEMKSNHHLRPTVEEKQMLTSVVER
                     LSQELEETE"
     gene            6702..7634
                     /locus_tag="VYO11_000272"
     CDS             6702..7634
                     /locus_tag="VYO11_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HEV1594892.1"
                     /translation="MMRSTKELRHVYRDFLLEANQSYSDIVVLEADLSSSMATHNLEK
                     DFGDRYVNVGIMEAEMVGLAAGLSIQGFRPYLHTFGPFASRRVFDQLFISLGYAQLDA
                     TVIGSDAGVTAEMNGGTHMPFEEIGLLRLIPKSIIFEATDDIQFREILNQTLDLKGLK
                     YIRTIRKAPVPVYQGGEDFSKGYIELRHGEDFVIVASGIMVAPSIRVADELSKLGYSV
                     GVIDLFRIKPIPEQIKTMLSGKTIFTVENHNQIGGIGSALCELFSDDGITKIHRMGVQ
                     ERFGQVGKMDYLLNEYGLSESNIKEKVLEIYNAR"
     gene            7867..9570
                     /gene="ilvD"
                     /locus_tag="VYO11_000273"
     CDS             7867..9570
                     /gene="ilvD"
                     /locus_tag="VYO11_000273"
                     /EC_number="4.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxy-acid dehydratase"
                     /protein_id="HEV1594893.1"
                     /translation="MTELDKRHRSSIYDSMVKSPNRAMLRATGMTDKDFETSIVGVIS
                     TWAENTPCNIHLHDFGKLAKEGVKSAGAWPVQFGTITVADGIAMGTPGMRFSLTSRDI
                     IADSIEAAMSGHNVDAFVAIGGCDKNMPGSMIAIANMDIPAIFAYGGTIAPGNLDGKD
                     IDLVSVFEGIGKWNHGDMTAEDVKRLECNACPGPGGCGGMYTANTMATAIEVLGMSLP
                     GSSSHPAESADKKEDIEAAGRAVVKMLELGLKPSDILTREAFEDAITVTMALGGSTNA
                     TLHLLAIAHAANVDLSLEDFNTIQERVPHLADLKPSGQYVFQDLYEVGGVPAVMKYLL
                     ANGFLHGDRITCTGKTVAENLADFADLTPGQKVIMPLENPKRADGPLIILNGNLAPDG
                     AVAKVSGVKVRRHVGPAKVFDSEEDAIQAVLTDEIVDGDVVVVRFVGPKGGPGMPEML
                     SLSSMIVGKGQGDKVALLTDGRFSGGTYGLVVGHIAPEAQDGGPIAYLRTGDIVTVDQ
                     DTKEISMAVSEEELEKRKAETTLPPLYSRGVLGKYAHIVSSASRGAVTDFWNMDKSGK
                     K"
     gene            complement(9686..9766)
                     /locus_tag="VYO11_000274"
                     /pseudo
     CDS             complement(9686..9766)
                     /locus_tag="VYO11_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(9824..10165)
                     /locus_tag="VYO11_000275"
     CDS             complement(9824..10165)
                     /locus_tag="VYO11_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003080443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HEV1594894.1"
                     /translation="MRDDIKINDRALALQDQIIEKLEKVFDTDVELDVYNLGLIYEIN
                     LDETGLCKIVMTFTDTACDCAESLPIEIVAGLKQIEGIKDIKVEVTWSPAWKITRISR
                     YGRIALGLPPR"
     gene            10289..11140
                     /gene="rgg"
                     /locus_tag="VYO11_000276"
     CDS             10289..11140
                     /gene="rgg"
                     /locus_tag="VYO11_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434947.1"
                     /note="Rgg, as the term is used in Streptococcus
                     pneumoniae, is the lone quorum-sensing system
                     transcriptional regulator related to proteins Rgg1, Rgg2,
                     Rgg3, and Rgg4 of Streptococcus pyogenes; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system transcriptional regulator
                     Rgg"
                     /protein_id="HEV1594895.1"
                     /translation="MEQIGKVFRQLRESRNISLRQATGGQFSPSMLSRFETGQSELSV
                     EKFLFALENISASVEEILFLARGFQYDTDSELRKEITDVLEPKNIAPLEDLYRREYQK
                     HAHSHNKQKHILNAIMIKSYMKSIDERVDLTAEEGKVLHDYLFSTEIWGIYELNLFSV
                     SSPFLSVSLFTRYVREMVRKSDFLMEMSGNRNFFHTILLNGFLASIECEEFTNASYFK
                     RVIEEHFYKENETYFRIVYLWAEGLLDSKQGRVKEGQKKMEDAVRIFEMLGCNKSAEY
                     YRNTTEC"
     gene            11331..12578
                     /locus_tag="VYO11_000277"
     CDS             11331..12578
                     /locus_tag="VYO11_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter"
                     /protein_id="HEV1594896.1"
                     /translation="MKLLFRNQAYRLLTLSRFFNAFGASIFNLVFIVYASTLSQASFA
                     VAMANIVMILPTLFTVFAGIRADYTRDKVKWMVYSGLFQAVLFFLAALVVQQASLFAF
                     SSLCLINVISDVISDFAGGLRMPLIKEKVAEDDLMEAYSFSQFITYISAIGGQAFGVW
                     LLALSVNNFSLVAGINACFFLVSATILFLGKSKLSLSMSFADGENLKNEKLSIKDQFL
                     TIYRNLRLVFLKSGQKNFGFMLFAVLLINSLGGALGGIYNIFFLSHSLLNFSYTEALF
                     INQFCVLVAIIISSLTGNDYFGKQSLPRLMMWETVGLSLVGLANLFNQVVLGLLFLFF
                     TLYVSGKVQPKISAMLMKNLAPEVLARTSNFFGLLFTLSIPVGTACFSLVAVWNIQLT
                     WMLFVGLSLLAIFLTILNLKNDI"
     gene            12656..13945
                     /locus_tag="VYO11_000278"
     CDS             12656..13945
                     /locus_tag="VYO11_000278"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HEV1594897.1"
                     /translation="MKLQKPKGTQDILPAESAKWQYVEGFAREIFKRYNYAEVRTPIF
                     EHYEVISRSVGDTTDIVTKEMYDFYDKGDRHITLRPEGTAPVVRSYVENKLFAPEVQK
                     PSKFYYMGPMFRYERPQAGRLRQFHQIGVECFGSSNPATDVETIAMAAHFLKEIGIQG
                     VKLHLNTLGNPESRAAYRQALIDYLTPLKETLSKDSQRRLEENPLRVLDSKEKEDKVA
                     VENAPSILDFLDEESQAHFDAVRQMLENLGVDYIIDTNMVRGLDYYNHTIFEFITEIE
                     GNDLTVCAGGRYDGLVSYFGGPETAGFGFGLGVERLLLILEKQGVTLPIENALDVYIA
                     VLGEGANIKALELVQALRQQGFKAERDYLNRKLKAQFKSADVFAAKTLITLGESEVES
                     GQVTVKNNQTREEVQVSLETISQNFSEIFEKLGFYTQ"
     gene            13942..14019
                     /locus_tag="VYO11_000279"
                     /pseudo
     CDS             13942..14019
                     /locus_tag="VYO11_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            14286..14600
                     /locus_tag="VYO11_000280"
     CDS             14286..14600
                     /locus_tag="VYO11_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1594898.1"
                     /translation="MWVLGFILFMIFFYSNNSKKIKKLENKIKKLERKEKGNAEMSRL
                     LQEMIGKEPIITGVYIGPDNWEVVDVDEEWVKLRRVDNTGKEKFKLQRIEDIQTVEFD
                     GE"
     gene            14610..14816
                     /locus_tag="VYO11_000281"
     CDS             14610..14816
                     /locus_tag="VYO11_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001176227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1594899.1"
                     /translation="MQLKNRLKELRARDGLNQTDLAKLAGVSRQTISLLERDEYTPSI
                     IIALKISQIFNETVESVFRLEEDE"
     gene            14816..15013
                     /locus_tag="VYO11_000282"
                     /pseudo
     CDS             14816..15013
                     /locus_tag="VYO11_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001046145.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            15016..15750
                     /locus_tag="VYO11_000283"
     CDS             15016..15750
                     /locus_tag="VYO11_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3169 family protein"
                     /protein_id="HEV1594900.1"
                     /translation="MKKKRRLLFLMSIVLGGFLGMFVGMFKARVESHEIILDVKALMP
                     WISAICLLIGFISMFLTFNFLKKSRKFHSLYQEEMDDDLNETYYVQMYRNLEFGTIAF
                     NITGVAIPLAIFISLSEVIILHTNPQTFFLSFLLFVVFLVAQKSLFKTIAIVRQFDLE
                     FFATPKDVLNYINSYDEGERQANLEQSFRILFQLHQYVLPALYIFLIIISFLTGEIQL
                     LAFLLVGAIHVYINVMQLPMVKRYFK"
     gene            15762..16403
                     /locus_tag="VYO11_000284"
     CDS             15762..16403
                     /locus_tag="VYO11_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV1594901.1"
                     /translation="MKLLKNLGWFLLALLSFFFIYGFIQGLATASLALGASPYAVTLL
                     YVVLAGVYVYGIYKWYQKAPVYIEKSGFNRFIWLPALVWFLSLVVQFFLPDDPSVNQQ
                     IATDLTLSQPLFSFFAVVIFAPLTEEIVFRGMLARYLFPKQDNSKRTLIFLLVSSLLF
                     ALIHFPGDVQQFFVYFSLGFSLGLAYISRKGLVYSISLHALNNLVGFLMILML"
     gene            16421..16651
                     /locus_tag="VYO11_000285"
     CDS             16421..16651
                     /locus_tag="VYO11_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000832182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1594902.1"
                     /translation="MKRVILLAVIQAVVLFFIIGALAYAFKGDFFYNYLAVVFAPIAG
                     VLRFGTAYITEIVLPRKAAEIAEKRKAGKNSK"
     gene            16693..16773
                     /locus_tag="VYO11_000286"
                     /pseudo
     CDS             16693..16773
                     /locus_tag="VYO11_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            16958..18721
                     /gene="aspS"
                     /locus_tag="VYO11_000287"
     CDS             16958..18721
                     /gene="aspS"
                     /locus_tag="VYO11_000287"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HEV1594903.1"
                     /translation="MKRSMYAGRVREEHIGQEITLKGWVGRRRDLGGLIFIDLRDREG
                     IMQLVINPEKVSAEVMATAESLRSEFVIEVTGQVAAREQANDKLPTGAVELNVTALIV
                     LNTAKTTPFEIKDGIEANDDTRLRYRYLDLRRPEMLENLKLRAKVTHSIRNYLDELEF
                     IDVETPFLSKSTPEGARDYLVPSRVNKGHFYALPQSPQITKQLLMNAGFDRYYQIVKC
                     FRDEDLRGDRQPEFTQVDLETSFLTEQEIQDITEGLIARVMKETKGIEVTLPFPRMKY
                     DDAMALYGSDKPDTRFDMLLQDLTEVVKGVDFKVFSEALAVKAIVVKGAADNYSRKDI
                     DKMTEVAKQYGAKGLAWVKVVDGELNGPVAKFLTGIQEELTTALALEDKDLVLFVADT
                     LEVANATLGALRGRIAKELGLIDNDKFNFLWVVDWPMFEWSEEEGRYMSAHHPFTLPQ
                     EETAHELEGDLAKVRAIAYDIVLNGYELGGGSLRINQKDLQERMFKALGFSAEEANDQ
                     FGFLLEAMDYGFPPHGGLAIGLDRFVMLLAGEENIREVIAFPKNNKATDPMTQAPSTV
                     ALKQLEELSLQVEEDETNKTN"
     gene            18699..19640
                     /locus_tag="VYO11_000288"
     CDS             18699..19640
                     /locus_tag="VYO11_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEV1594904.1"
                     /translation="MKQTKRIKRWRYYLRRFAYQIKILRVLQSISREKYDEKISASLV
                     YGFLSAVAVNFFFQPGHVYSSGATGLAQIISALSNHWFGFHIPISLSFYAINFPLMVL
                     AWYQIGHKFTVFTFITVSMSSFFIQFVPVATLTEDPIINSLFGGVVMGLGIGFALRNN
                     ISSGGTDIVSLTIRKKTGKNVGSISFLVNGTIMLIAGLTFGWKYALYSMITIFVSSRV
                     TDAVFTKQKRMQAMIVTNHPEKVIEKIHKKLHRGATMIHDAEGTYNHERKAVLITVIT
                     RAEFNEFKQIMTQVDPSSFVSVSENVHILGRFVEIDN"
     gene            complement(19805..19885)
                     /locus_tag="VYO11_000289"
                     /pseudo
     CDS             complement(19805..19885)
                     /locus_tag="VYO11_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(20021..21007)
                     /locus_tag="VYO11_000290"
     CDS             complement(20021..21007)
                     /locus_tag="VYO11_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV1594905.1"
                     /translation="MPVTIKDVAKAAGVSPSTVTRVIQNKSTISDETKKRVRKAMKEL
                     NYHPNLNARSLVSSYTQVIGLVLPDDSDAFYQNPFFPSVLRGISQVASENHYAIQIAT
                     GKDEKERLNAISQMVYGKRVDGLIFLYAQEEDPLVKLVAEEQFPFLILGKSLSPFIPL
                     VDNDNVQAGFDATEYFIKKGCKRIAFIGGSKKLFVTKDRLTGYEQALKHYKLTTDNNR
                     IYFADEFLEEKGYKFSKRLFKHDPQIDAIITTDSLLAEGVCNYIAKHQLDVPVLSFDS
                     VNPKLNLAAYVDINSLELGRVSLETILQIINDNKNNKQICYRQLIAHKIIEK"
     gene            complement(21017..21817)
                     /locus_tag="VYO11_000291"
     CDS             complement(21017..21817)
                     /locus_tag="VYO11_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000938258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HEV1594906.1"
                     /translation="MLPYPFSYFSSIWGFRKPLSKRFELNWFQLLFTSIFLISLSMVP
                     IAIQNSSQETYPLETFIDNVYEPLTNEVVQDLSEHATIVDGTLTYTGTASQAPSVVIG
                     PSQIKELPKDLQLHFDTNELVISKESKELTRISYRAIQTESFKSKDSLTQAISKDWYQ
                     QNRVYISLFLVLGASFLFGLNFFIVSLGASLLLYITKKSRLFSFRTFKECYHFILNCL
                     GLPTLITLILGLFGQNMTTLITVQNILFVLYLVTIFYKTHFRDPNYHK"
     gene            complement(22070..22912)
                     /locus_tag="VYO11_000292"
     CDS             complement(22070..22912)
                     /locus_tag="VYO11_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001065636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV1594907.1"
                     /translation="MNNSIKLKRRLTQSLTYLYLIGLSIVIIYPLLITIMSAFKAGNV
                     SAFKLDTNIDLNFDNFKGLFTETLYGTWYLNTLIIALITMAVQTSIIVLAGYAYSRYN
                     FLARKQSLVFFLIIQMVPTMAALTAFFVMALMLNALNHSWFLIFLYVGGGIPMNAWLM
                     KGYFDTVPMSLDESAKLDGAGHFRRFWQIVLPLVRPMVAVQALWAFMGPFGDYILSSF
                     LLREKEYFTVAVGLQTFVNNAKNLKIAYFSAGAILIALPICILFFFLQKNFVSGLTSG
                     GDKG"
     gene            complement(22914..24206)
                     /locus_tag="VYO11_000293"
     CDS             complement(22914..24206)
                     /locus_tag="VYO11_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000414940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV1594908.1"
                     /translation="MEKQQPSKAALLSIIPGLGQIYNKQKAKGFIFLGVTIVFVLYFL
                     ALATPELSNLITLGDKPGRDNSLFMLIRGAFHLIFVIVYVLFYFSNIKDAHTIAKRIN
                     NGIPVPRTLKDMIKGIYENGFPYLLIIPSYVAMTFAIIFPVIVTLMIAFTNYDFQHLP
                     PNKLLDWVGLTNFTNIWSLSTFRSAFGSVLSWTIIWALAASTLQIVIGIFTAIIANQP
                     FIKGKRIFGVIFLLPWAVPAFITILTFSNMFNDSVGAINTQVLPILAKFLPFLDGALI
                     PWKTDPTWTKIALIMMQGWLGFPYIYVLTLGILQSIPNDLYEAAYIDGANAWQKFRNI
                     TFPMILAVAAPTLISQYTFNFNNFSIMYLFNGGGPGSVGGGAGSTDILISWIYRLTTG
                     TSPQYSMAAAVTLIISIIVISISMIAFKKLHAFDMEDV"
     gene            complement(24317..25588)
                     /locus_tag="VYO11_000294"
     CDS             complement(24317..25588)
                     /locus_tag="VYO11_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000095461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEV1594909.1"
                     /translation="MSSKFMKSTAVLGTATLASLLLVACGSKTADKPADSGSSEVKEL
                     TVYVDEGYKSYIEEVAKAYEKEAGVKVTLKTGDALGGLDKLSLDNQSGNVPDVMMAPY
                     DRVGSLGSDGQLSEVKLSDGAKTDDTTKSLVTAANGKVYGAPAVIESLVMYYNKDLVK
                     DAPKTFADLENLAKDSKYAFAGEDGKTTAFLADWTNFYYTYGLLAGNGAYVFGQNGKD
                     AKDIGLANDGSIAGINYAKSWYEKWPKGMQDTEGAGNLIQTQFQEGKTAAIIDGPWKA
                     QAFKDAKVNYGVATIPTLPNGKEYAAFGGGKAWVIPQAVKNLEASQKFVDFLVATEQQ
                     KVLYDKTNEIPANTEARSYAEGKNDELTTAVIKQFKNTQPLPNISQMSAVWDPAKNML
                     FDAVSGQKDAKTAANDAVTLIKETIKQKFGE"
     gene            26138..27655
                     /gene="malQ"
                     /locus_tag="VYO11_000295"
     CDS             26138..27655
                     /gene="malQ"
                     /locus_tag="VYO11_000295"
                     /EC_number="2.4.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-alpha-glucanotransferase"
                     /protein_id="HEV1594910.1"
                     /translation="MKKRQSGVLMHISSLPGAYGIGSFGQSAYDFVDFLVRTKQRYWQ
                     ILPLGATSYGDSPYQSFSAFAGNTHFIDLDILVEQGLLEASDLEGVDFGSDASEVDYA
                     KIYYARRPLLEKAVKRFFEVGDVKDFEKFAQDNQSWLELFAEYMAIKEYFDNLAWTEW
                     PDADARARKASALESYREQLADKLVYHRVTQYFFFQQWLKLKAYANDNHIEIVGDMPI
                     YVAEDSSDMWANPHLFKTDVNGKATCIAGCPPDEFSVTGQLWGNPIYDWEAMDKDGYK
                     WWIERLRESFKIYDIVRIDHFRGFESYWEIPAGSDTAAPGEWVKGPGYKLFAAVKEEL
                     GELNIIAEDLGFMTDEVIELRERTGFPGMKILQFAFNPEDESIDSPHLAPANSVMYTG
                     THDNNTVLGWYRNEIDDATREYMARYTNRKEYETVVHAMLRTVFSSVSFMAIATMQDL
                     LELDEAARMNFPSTLGGNWSWRMTEDQLTPAVEEGLLDLTTIYRRINENLVDLKK"
     gene            27681..29939
                     /gene="glgP"
                     /locus_tag="VYO11_000296"
     CDS             27681..29939
                     /gene="glgP"
                     /locus_tag="VYO11_000296"
                     /EC_number="2.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000950172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan family
                     phosphorylase"
                     /protein_id="HEV1594911.1"
                     /translation="MLSLQEFVQNRYNKTIAECSNEELYLALLNYSKLASSQKPVNTG
                     KKKVYYISAEFLIGKLLSNNLINLGLYDDVKKELAAAGKDLIEVEEVELEPSLGNGGL
                     GRLAACFIDSIATLGLNGDGVGLNYHFGLFQQVLKNNQQETIPNAWLTEQNWLVRSSR
                     SYQVPFADFTLTSTLYDIDVTGYETATKNRLRLFDLDSVDSSIIKDGINFDKTDIARN
                     LTLFLYPDDSDRQGELLRIFQQYFMVSNGAQLIIDEAIEKGSNLHDLADYAVVQINDT
                     HPSMVIPELIRLLTARGIELDEAISIVRSMTAYTNHTILAEALEKWPLEFLQEVVPHL
                     VPIIEELDRRVKAEYKDPAVQIIDESGRVHMAHMDIHYGYSVNGVAALHTEILKNSEL
                     KAFYDLYPEKFNNKTNGITFRRWLMHANPRLSHYLDEILGDGWHHEADELEKLLSYED
                     KAAVKEKLESIKAHNKRKLARHLKEHQGVEINSNSIFDIQIKRLHEYKRQQMNALYVI
                     HKYLDIKAGNIPARPITIFFGGKAAPAYTIAQDIIHLILCMSEVIANDPAVAPHLQVV
                     MVENYNVTAASFLIPACDISEQISLASKEASGTGNMKFMLNGALTLGTMDGANVEIAE
                     LVGEENIYIFGEDSETVIDLYAKAAYKSSEFYAREAIKPLVDFIVSDAVLAAGNKERL
                     ERLYNELINKDWFMTLLDLEDYIKVKEQMLADYEDRDAWLDKVIVNISKAGFFSSDRT
                     IAQYNEDIWHLN"
     gene            complement(30984..31511)
                     /locus_tag="VYO11_000297"
     CDS             complement(30984..31511)
                     /locus_tag="VYO11_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1594912.1"
                     /translation="MLIVSAIPSVSAVYASEQVSQIETNMELQPVTSLTEEQINTLAN
                     EIQSFHPDVSQQWIKEVINRQLQGDYTIPPTYSPFRAAWQGITVNQMGALLDTAIALA
                     LGGTTAGLANLIKVKGKHAAKSAIRSAISRYLGSWFVNDVALEFAMNLLSPGTYLAQL
                     WDKNDAIPNNGRINF"
     gene            complement(32445..33293)
                     /locus_tag="VYO11_000298"
     CDS             complement(32445..33293)
                     /locus_tag="VYO11_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HEV1594913.1"
                     /translation="MNTNLKPKLQRFASATAFACPICQENLTLLETNFKCCNRHSFDL
                     AKFGYVNLAPQIKQSANYDKENFQNRQQILEAGFYQAILDAVSDLLASSKTTTTILDI
                     GCGEGFYSRKLQESHSEKTFYAFDISKDSVQIAAKSEPNWAVNWFVGDLARLPIKDAN
                     MDILLDIFSPANYGEFRRVLSKDGILIKVIPTENHLKEIRQRVQDQLTNKEYSNQDIK
                     EHFQEHFTILSSQTASLTKTITAEQLQALLSMTPLLFHVDQSKIDWSQLTEITIEAEI
                     LVGKAF"
     gene            33445..33723
                     /locus_tag="VYO11_000299"
     CDS             33445..33723
                     /locus_tag="VYO11_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003075836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1594914.1"
                     /translation="MLKEVLTVAKVAKKSSLFLGGVAFGTLGLKILASKEAKKGYSKA
                     LAKAYKLKDELDASVSVVKQHGDDVLQDAKYLYEQEKKEEQLDSLIGE"
     gene            33725..35788
                     /locus_tag="VYO11_000300"
     CDS             33725..35788
                     /locus_tag="VYO11_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000008803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HEV1594915.1"
                     /translation="MSFKVLHRGYQHIRLSSSFSLTLDIQDYLRSLARDEKGIESIQF
                     YMDQQHFTLRIKEGFSVLDNAEAFLKRIDKGKVSELMTLPIRREESAYSIVSGAAVKR
                     VLFRSFVPYPIRYIWTCYQALGYIREAYQTLARKELTMEVLDCSAILLSLFMNQSKTA
                     SNIMFMLDLGNHLDQWSLKKTATDLEQSLLAKESDVFLVQGDTVVSIKSSDVQIGDVL
                     ILSQGNEILFDGQVVSGLGMVNESSLTGESFPVEKRESDLVCANTVLETGELRIRVTD
                     NQMNSRILQLIELMKKSEENKKTKQRYFIKMADKVVKYNFLGAGLTYLLTGSFSKAIS
                     FLLVDFSCALKISTPVAYLTVIKEGLNREMVIKDGDVLEKYLEVDTFLFDKTGTITTS
                     YPIVEKVLPFGDYSEEDILRISACLEEHIYHPIANAIVKQAEIEGIEHEEMHGKLQYI
                     ASKGIKSHIDGQPVLIGNYVLMQDEQIHISSEQNALIEEYKSHYNLLFLAYQNELIGM
                     FCIHTPLRKEAKTALDKLKAQGKKLILATGDTLIRTEELVKDLPFDQVYTDLKPDGKF
                     ELVEKLQKAGHTILMVGDGLNDSAALTLSDIGVVMNESADISKQMSDILLLDNRLDFF
                     QELDSLSSSLQTLIKKNIQDTVVVNSSLIGFGLFNWLSPSNLSILHNLTTLRIVLRSL
                     SIKNR"
     gene            complement(35866..37122)
                     /locus_tag="VYO11_000301"
     CDS             complement(35866..37122)
                     /locus_tag="VYO11_000301"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000546895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HEV1594916.1"
                     /translation="MHIFDELKERGLIFQTTDEEALRKALEEGQVSYYTGYDPTADSL
                     HLGHLVAILTSRRLQLAGHKPYALVGGATGLIGDPSFKDAERSLQTKDTVDGWVKSIQ
                     GQLSRFLDFENGENKAVMVNNYDWFGSISFIDFLRDIGKYFTVNYMMSKESVKKRIET
                     GISYTEFAYQIMQGYDFFVLNQDHNVTLQIGGSDQWGNMTAGTELLRRKADKTGHVIT
                     VPLITDATGKKFGKSEGNAVWLNPEKTSPYEMYQFWMNVMDADAVRFLKIFTFLSLDE
                     IEDIRKQFEAAPHERLAQKVLAREVVTLVHGEEAYKEALNITEQLFAGNIKNLSVKEL
                     KQGLRGVPNYQVQADENNNIVELLVSSGIVNSKRQAREDVQNGAIYVNGDRIQDLDYV
                     LSDADKLENELTVIRRGKKKYFVLTY"
     gene            37264..39726
                     /locus_tag="VYO11_000302"
     CDS             37264..39726
                     /locus_tag="VYO11_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEV1594917.1"
                     /translation="MQNQLNELKRKMLEFFQQKQKNKKSARPGKKGSSTKKSKTLDKS
                     AIFPAILLSIKALFNLLFVLGFLGGMLGAGIALGYGVALFDKVRVPQTEELVNQVKDI
                     SSISEITYSDGTVIASIESDLLRTSISSEQISENLKKAIIATEDEHFKEHKGVVPKAV
                     IRATLGKFVGLGSSSGGSTLTQQLIKQQVVGDAPTLARKAAEIVDALALERAMTKDEI
                     LTTYLNVAPFGRNNKGQNIAGARQAAEGIFGVDASQLTVPQAAFLAGLPQSPITYSPY
                     ENTGELKSDEDLEIGLRRAKAVLYSMYRTGALSKDEYSQYKDYDLKQDFLPSGTVTGI
                     SRDYLYFTTLAEAQERMYDYLAQRDNVSAKELKNEATQKFYRDLAAKEIENGGYKITT
                     TIDQKIHSAMQSAVADYGYLLDDGTGRVEVGNVLMDNQTGAILGFVGGRNYQENQNNH
                     AFDTKRSPASTTKPLLAYGIAIDQGLMGSETILSNYPTNFANGNPIMYANSKGTGMMT
                     LGEALNYSWNIPAYWTYRMLREKGVDVKGYMEKMGYEIPEYGIESLPMGGGIEVTVAQ
                     HTNGYQTLANNGVYHQKHVISKIEAADGRVVYEYQDKPVQVYSKATATIMQGLLREVL
                     SSRVTTTFKSNLTSLNPTLANADWIGKTGTTNQDENMWLMLSTPRLTLGGWIGHDDNH
                     SLSRRAGYSNNSNYMAHLVNAIQQASPSIWGNEHFALDPSVVKSEVLKSTGQKPGKVS
                     VEGKEVEVTGSTVTSYWANKSGAPATSYRFAIGGSDADYQNAWSSIVGSLPTPSSSSS
                     SSSSSSDSSNSSTTRPSSRARR"
     gene            39791..40702
                     /locus_tag="VYO11_000303"
     CDS             39791..40702
                     /locus_tag="VYO11_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HEV1594918.1"
                     /translation="MNQYQKKIVNGKIYSLLSGLIWGICGILGEYFFTHYQVSSGWIT
                     SMRLTLAGSLVLIWSAIQLKSQVLDIWRDKKNYLPFLAYAILGIFSVQYFFYLCVEYS
                     NATTATILQFISPVFILFYNRLVYQKRASKSAVFYVLVAMLGVCLMATKGDLSQLSMT
                     PLALITGLLSAMGVMFNVILPQPFAKRYGFVPTVGWGMILAGLFSNVLSPVYQLSFTL
                     DIWSILICLIIAFFGTAFAFFISMKAVSLVSPLVVSVISASEPLSSALLSVLFLGLVV
                     DWSLLLAIALIILPMIFLSIEEAKESR"
     gene            40932..41630
                     /gene="dapD"
                     /locus_tag="VYO11_000304"
     CDS             40932..41630
                     /gene="dapD"
                     /locus_tag="VYO11_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HEV1594919.1"
                     /translation="MTATKMNAQEIIQFIANAEKKTSVKVTFEGQLATAVPSSVVKLG
                     NVLFGDWKDVAPLLEGLVENQDYVVEQDARNSAVPLLDKRAINARIEPGAIIRDQVEI
                     GDNAVIMMGAVINIGAEIGAGTMIDMGAILGGRAIVGKNSHVGAGAVLAGVIEPASAE
                     PVRVGDNVLIGANAVVIEGVQIGSGSVVAAGAIVTQDVPENVVVAGVPARIIKEIDAQ
                     TQQKTALEDALRTL"
     gene            41698..42828
                     /locus_tag="VYO11_000305"
     CDS             41698..42828
                     /locus_tag="VYO11_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyldiaminopimelate deacetylase"
                     /protein_id="HEV1594920.1"
                     /translation="MLDLIQTRRDLHQIPEIGLEEFKTQAYLLDVIEKLTTGKDFVQI
                     RTWRTGILVYLQGSQPERTIGWRTDIDGLPIVEQTGLPFASQHQGRMHACGHDFHMTI
                     ALGCLERALEEQPKNNLLFLFQPAEENEAGGMLMYEDGAFGDWLPNQFYGLHVRPDLK
                     VGQIATNTHTLFAGTCEVKIRFKGKGGHAAFPHEANDALVAASYFVTQVQSVVSRNVN
                     PIEGAVVTFGVFQAGTTNNVITDTAFLHGTIRALTQDMSLLVQKRVKTVAEGVAAAFD
                     MEVEVELKQGGYLPVENNPALARELMDFFDEKDGIELIDIEPAMTGEDFGYLLSKVDG
                     VMFWLGIDSPYALHHPQMSPKEEVLAIGVAAVSSFLKKKAAE"
     gene            42840..43379
                     /locus_tag="VYO11_000306"
     CDS             42840..43379
                     /locus_tag="VYO11_000306"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HEV1594921.1"
                     /translation="MKSELRKQVLHEMKALSQEQKQAIDQALTERILQHPFYQEAKVI
                     ATYLSFSHEFQTRELIEQALKDGKKVLIPKTYPKGRMDFVVYDPQQLVKTAFALLEPQ
                     GDLEVVDVSQIDLIHVPGLAFTTDGYRIGYGGGYYDRYLEHFSGRTLSTVHPCQIQDF
                     IPENHDIPVQEVLIDEGNL"
     gene            43363..44040
                     /locus_tag="VYO11_000307"
     CDS             43363..44040
                     /locus_tag="VYO11_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HEV1594922.1"
                     /translation="MKEIFDRRYPVTSFFLLVTALVFLLMLVTAGGNFDRADTLFRFG
                     AMYGPAIRLFPEQVWRLLSAIFVHIGWEHFIVNMLSLYYLGRQVEEIFGSKQFFFLYL
                     LSGMMGNLFVFVFSPKSLAAGASTSLYGLFAAIIVLRYATRNPYIQQLGQSYLTLFVV
                     NIIGSVLIPGISLAGHIGGAVGGAFLAVIFPVRGEKRMYNTSQRLGAVVLFVGLAILL
                     FYKGMGM"
     gene            44054..44131
                     /locus_tag="VYO11_000308"
                     /pseudo
     CDS             44054..44131
                     /locus_tag="VYO11_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(44341..45276)
                     /locus_tag="VYO11_000309"
     CDS             complement(44341..45276)
                     /locus_tag="VYO11_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1594923.1"
                     /translation="MENKFVEFIENNKKVIISSVAVGVVLVLGFGWYSYNQQQAEQQA
                     KIVQLEKDSKSDKEQVDKLFESFDASSDESISKLKELSETSLKTDAGKDYLNNKVKES
                     SKAIVDFHLQKGLAYDVKDSDEKFKDKATLETNVKEITKQIDFIKKVDETFKQENLEE
                     TLKSLNDLVDKYQKQIELLKKEEEKAAEKAKESSSQSNSSSGASNESYNGSSNSNVDY
                     SSSEQTNGYSNNYGSQSYSGSGDSSTNGGSSEQYSSSNSNSGVNNGYYKKYKNIGADG
                     HVSYTYDNESNGDVFDENWNYLGNTGGGIAEPPQR"
     gene            complement(45694..46593)
                     /gene="galU"
                     /locus_tag="VYO11_000310"
     CDS             complement(45694..46593)
                     /gene="galU"
                     /locus_tag="VYO11_000310"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HEV1594924.1"
                     /translation="MTSKVRKAVIPAAGLGTRFLPATKALAKEMLPIVDKPTIQFIVE
                     EALKSGIEDILVVTGKSKRSIEDHFDSNFELEYNLKEKGKTDLLKLVDETTGMRLHFI
                     RQTHPRGLGDAVLQAKAFVGNEPFVVMLGDDLMDITDEKAVPLTKQLMDDYERTHAST
                     IAVMPVPHDEVSAYGVIAPQGEGKDGLYSVETFVEKPAPEDAPSDLAIIGRYLLTPEI
                     FEILEKQAPGAGNEIQLTDAIDTLNKTQRVFAREFKGARYDVGDKFGFMKTSIDYALK
                     HPQVKDDLKNYLIQLGKELTEKE"
     gene            complement(46615..47631)
                     /locus_tag="VYO11_000311"
     CDS             complement(46615..47631)
                     /locus_tag="VYO11_000311"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000415108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HEV1594925.1"
                     /translation="MEKQTVAVLGPGSWGTALSQVLNDNGHEVRIWGNLPEQINEINT
                     HHTNKHYFKDVVLDENIIAYTDLAETLKDVDAILFVVPTKVTRLVAQQVAQTLDHKVI
                     IMHASKGLEPDSHKRLSTILEEEIPEHLRSDIVVVSGPSHAEETIVRDLTLITAASKD
                     LQTAQYVQKLFSNHYFRLYTNTDVIGVETAGALKNIIAVGAGALHGLGFGDNAKAAII
                     ARGLAEITRLGVALGASPLTYSGLSGVGDLIVTGTSIHSRNWRAGDALGRGESLADIE
                     ANMGMVIEGISTTRAAYELAQELGVYMPITQAIYQVIYHGTNIKDAIYDIMNNEFKAE
                     NEWS"
     gene            47843..48223
                     /locus_tag="VYO11_000312"
     CDS             47843..48223
                     /locus_tag="VYO11_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV1594926.1"
                     /translation="MREFGEKIKRLRLAKKISRSEFCGDESELSIRQLIRIENGESRP
                     TLTKLKYIAERLGVEDYKLMPSYIELDKEYLELKYFLMRTPTYEDETIAQKKESVLIR
                     FLKSIMIGYLRKKDLSSQIIHIWH"
     gene            complement(48397..48822)
                     /locus_tag="VYO11_000313"
     CDS             complement(48397..48822)
                     /locus_tag="VYO11_000313"
                     /inference="COORDINATES: protein motif:HMM:NF025080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV1594927.1"
                     /translation="MTNLSSVDSEELFQFYRERGNAENFIKERKAGFFGDKTDSSTMI
                     KNEVRMMIGCLAYNLYLFLKQLAGDEVKSLTIKRFRRLFLHIAGKYVSTARRHILKFS
                     SLYAYSKQFQALFDTICQINLILPVPYRARGQGKTCLTE"
     gene            complement(48890..49540)
                     /gene="phoU"
                     /locus_tag="VYO11_000314"
     CDS             complement(48890..49540)
                     /gene="phoU"
                     /locus_tag="VYO11_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HEV1594928.1"
                     /translation="MRNQFDLELHELEQSFLGLGQLVLETASKTLLALASKDKEMAEL
                     IINKDHAINQGQSAIELTCARLLALQQPQVSDLRFVISIMSSCSDLERMGDHMAGIAK
                     AVLQLKENQLAPDEEQLHQMGKLSLSMLSDLLVAFPLHQASKAISIAQKDEQIDQYYY
                     ALSKEIIGLMKDQETSIPNGTQYLYIIGHLERFADYIANICERLVYLETGELVDLN"
     gene            complement(49555..50307)
                     /gene="pstB"
                     /locus_tag="VYO11_000315"
     CDS             complement(49555..50307)
                     /gene="pstB"
                     /locus_tag="VYO11_000315"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003101281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEV1594929.1"
                     /translation="MGTFSVRHLDLFYGDFQALKNISIQLPERQITALIGPSGCGKST
                     FLKTLNRMNDLVPSCHIEGQVLLDEQDIYSSKFNLNQLRKRVGMVFQQPNPFAMSIYD
                     NVAYGPRTHGIRDKKQLDALVEKSLKGAAIWDEVKDNLKKSAMSLSGGQQQRLCIARA
                     LAVEPDVLLMDEPTSALDPISTLKIEDLIQQLKKDYTIIIVTHNMQQASRISDKTAFF
                     LTGEICEFGDTVDVFTNPKDQRTEDYISGRFG"
     gene            complement(50309..51124)
                     /gene="pstA"
                     /locus_tag="VYO11_000316"
     CDS             complement(50309..51124)
                     /gene="pstA"
                     /locus_tag="VYO11_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HEV1594930.1"
                     /translation="MSKYLLKLLVYCFSALTFGSLFLIIGFILIKGLPHLSLSLFSWT
                     YTSENISLMPAIISTVILVFGALLLALPIGIFAGFYLVEYTKKDSLCVKIMRLASDTL
                     SGIPSIVFGLFGMLFFVVFLGFQYSLLSGILTSVIMVLPVIIRSTEEALLSVSDSMRQ
                     ASYGLGAGKLRTVFRIVLPVAMPGILAGVILAIGRIVGETAALMYTLGTSTNTPSSLM
                     SSGRSLALHMYMLSSEGLHVNEAYATGVILIITVLMINTLSSLLSRKLVKGAS"
     gene            complement(51117..51980)
                     /gene="pstC"
                     /locus_tag="VYO11_000317"
     CDS             complement(51117..51980)
                     /gene="pstC"
                     /locus_tag="VYO11_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HEV1594931.1"
                     /translation="MTKQAFKEAVFRAIFFMSATVAVVAILLICFFIFSNGLPFIANY
                     GFARFLLGSDWSPTNIPASYGILPMIVGSLLITLGAIVIGVPTGILTSVFMVYYCPKP
                     VYGFLKSAINLMAAIPSIVYGFFGLQLLVPWIRSFLGNGMSVLTASLLLGIMILPTII
                     SLSESAIRTVPKTYYSGSLALGASHERSIFSVILPAARSGILSAVILGIGRAVGETMA
                     VILVAGNQPIIPSGLFSGTRTLTTNIVLEMAYASGQHREALIATSAVLFFLILLINAY
                     FAYLKGKSSYE"
     gene            complement(52098..52973)
                     /locus_tag="VYO11_000318"
     CDS             complement(52098..52973)
                     /locus_tag="VYO11_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate-binding protein"
                     /protein_id="HEV1594932.1"
                     /translation="MKFKKMLTLAAIGLSGFGLVACGNQSAASKQSASGTIEVISREN
                     GSGTRGAFTEITGILKKDGDKKIDNTAKTAVIQNSTEGVLSAVQGNANAIGYISLGSL
                     TKSVKALEIDGVKASRDTVLDGEYPLQRPFNIVWSSNLSKLGQDFISFIHSKQGQQVV
                     TDNKFIEAKTETTEYTSQHLSGKLSVVGSTSVSSLMEKLAEAYKKENPEVTIDITSNG
                     SSAGITAVKEKTADIGMVSRELTPEEGKSLTHDAIALDGIAVVVNNDNKASQVSMAEL
                     ADVFSGKLTTWDKIK"
     gene            complement(53140..54471)
                     /locus_tag="VYO11_000319"
     CDS             complement(53140..54471)
                     /locus_tag="VYO11_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HEV1594933.1"
                     /translation="MKRYLQFWLVNLSVSLILIAGMALTWISKGIGLFLLALSLGQGG
                     YWLFCLWKWEVAFETLHQPLLTSSEYFLEKGQEDLKSLAQYVSGLKTKVSQQDQQYKD
                     LAETMEVLLSHLTMGTFLVSAQGQMLLSSRSLPHYFPDVDGDISSLDDLKRMDIRNLV
                     HQAFDQKTRLKQEVSGFHEGDLILEVTAVPVFSPTQSVEAVLVLLYDLTTIRTYEKLN
                     LAFVSNASHELRTPVTSIKGFAETIKGMSAEEEALKDDFLDIIYKESLRLEHIVEHLL
                     TLSKAQQMPIQWTTLSLAEFVQDLTQSLQPQLKKKDLQLKVQVPDDVTLVSDSQLLSQ
                     ILLNLLSNAIRYTEQGGKIEVKTQKVNEGIKISVSDTGIGISQLEQDRIFERFYRVNK
                     GRSRQTGGTGLGLAIVKELSQLLGGQVTVTSQLGRGSCFTIFLPNQSFAQD"
     gene            complement(54472..55179)
                     /locus_tag="VYO11_000320"
     CDS             complement(54472..55179)
                     /locus_tag="VYO11_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1594934.1"
                     /translation="MTKQVLLVDDEEHILKLLDYHLSKEGFSTQLVTNGRKALALAET
                     EPFDFILLDIMLPQLDGMEVCKRLRAKGVKTPIMMVSAKSDEFDKVLALELGADDYLT
                     KPFSPRELLARVKAVLRRTKGEQEGDDSDNIADDSWLFGTLKVYPERHEVYKANKLLS
                     LTPKEFELLLYLMKHPNMTLTRERLLERIWGYDFGQETRLVDVHIGKLREKIEDNPKA
                     PQFIRTIRGYGYKFKEL"
     gene            complement(55263..55739)
                     /locus_tag="VYO11_000321"
     CDS             complement(55263..55739)
                     /locus_tag="VYO11_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000356607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HEV1594935.1"
                     /translation="MDKEDLIRTLELAPHVEGGYFRQTKKASDTINLAGKGRALYTSI
                     YFLLEETNPSHFHRLTADEIWYFHAGSPLTVHMITADGHYEAVTLVLDISKGQQLHYC
                     VPKSTIWGSTVDKDYALVSCLVAPGFEFEDFELFERADLLATYPEHKEMIEHLTRY"
     gene            55746..56292
                     /locus_tag="VYO11_000322"
                     /pseudo
     CDS             55746..56292
                     /locus_tag="VYO11_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(56682..58373)
                     /locus_tag="VYO11_000323"
     CDS             complement(56682..58373)
                     /locus_tag="VYO11_000323"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HEV1594936.1"
                     /translation="MNTKELIASELASIIDNLDQEAILKLLETPKNSEMGDIAFPAFS
                     LAKVERKAPQMIAAELAEKMNSQAFEKVVATGPYVNFFLDKSAISAQVLQAVTTEKEH
                     YADQNIGKQENVVIDMSSPNIAKPFSIGHLRSTVIGDSLSHIFQKIGYQTVKVNHLGD
                     WGKQFGMLIVAYKKWGDEEAVKAHPIDELLKLYVRINAEAENDPSLDEEAREWFRKLE
                     NGDEEALALWQWFRDESLVEFNRLYNELKVEFDSYNGEAFYNDKMDAVVDILSEKGLL
                     LESEGAQVVNLEKYGIEHPALIKKSDGATLYITRDLAAALYRKNEYQFAKSIYVVGQE
                     QSAHFKQLKAVLQEMGYDWSDDITHVPFGLVTKEGKKLSTRKGNVILLEPTVAEAVSR
                     AKVQIEAKNPELENKDQVAHAVGVGAIKFYDLKTDRTNGYDFDLEAMVSFEGETGPYV
                     QYAYARIQSILRKADFKPETAGNYSLNDTESWEIIKLIQDFPRIINRAADNFEPSIIA
                     KFAISLAQSFNKYYAHTRILDESPERDSRLALSYATAVVLKEALRLLGVEAPEKM"
     gene            58509..58955
                     /gene="argR"
                     /locus_tag="VYO11_000324"
     CDS             58509..58955
                     /gene="argR"
                     /locus_tag="VYO11_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEV1594937.1"
                     /translation="MRKRDRHQLIKKMITEEKLSTQKEIQDRLEAHNVCVTQTTLSRD
                     LREIGLTKVKKNDMVYYVLVNETEKIDLVEFLSHHLEGVARAEFTLVLHTKLGEASVL
                     ANIVDVNKDEWILGTVAGANTLLVICRDQHVAKLMEDRLLDLMKDK"
     gene            59006..61540
                     /gene="mutS"
                     /locus_tag="VYO11_000325"
     CDS             59006..61540
                     /gene="mutS"
                     /locus_tag="VYO11_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HEV1594938.1"
                     /translation="MAIEKLSPGMQQYVDIKKQYPDAFLLFRMGDFYELFYEDAVNAA
                     QILEISLTSRNKNADNPIPMAGVPYHSAQQYIDVLIEQGYKVAIAEQMEDPKQAVGVV
                     KREVVQVITPGTVVDSSKPDSQNNFLVSIDCEGNQFGLAYMDLVTGDFYVTGLLDFTL
                     VCGEIRNLKAREVVLGYDLSEEEEQILSRQMNLVLSYEKESFEDLHLLDLRLATVEQT
                     ASSKLLQYVHRTQMRELNHLKPVIRYEIKDFLQMDYATKASLDLVENARSGKKQGSLF
                     WLLDETKTAMGMRLLRSWIYRPLIDKERIVQRQEVVQVFLDHFFERSDLTDSLKGVYD
                     IERLASRVSFGKTNPKDLLQLATTLSSVPRIRAILEGMEQPTLAYLIAQLDAIPELES
                     LISAAIAPEAPHVITDGGIIRTGFDETLDKYRCVLREGTSWIAEIEAKERENSGISTL
                     KIDYNKKDGYYFHVTNSQLGNVPAHFFRKATLKNSERFGTEELARIEGDMLEAREKSA
                     NLEYEIFMRIREEVGKYIQRLQALAQGIATVDVLQSLAVVAETQHLIRPEFGDDSQID
                     IRKGRHAVVEKVMGAQTYIPNTIQMAEDTSIQLVTGPNMSGKSTYMRQLAMTAVMAQL
                     GSYVPAESAHLPIFDAIFTRIGAADDLVSGQSTFMVEMMEANNAISHATKNSLILFDE
                     LGRGTATYDGMALAQSIIEYIHEHIGAKTLFATHYHELTSLESSLQHLVNVHVATLEQ
                     DGQVTFLHKIEPGPADKSYGIHVAKIAGLPADLLARADKILTQLENQGTESPPPMRQT
                     SAVTEQISLFDRAEEHPILAELAKLDVYNMTPMQVMNVLVELKQKL"
     gene            61687..63381
                     /gene="patA"
                     /locus_tag="VYO11_000326"
     CDS             61687..63381
                     /gene="patA"
                     /locus_tag="VYO11_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatA"
                     /protein_id="HEV1594939.1"
                     /translation="MLIQKIKTYKWQALASLLMTGLMVASSLLQPRYLQEVLGALLTG
                     KYEAIYSIGAWLIGVAVVGLVAGGLNVVLAAYIAQGVSSDLREDAFRKIQTFSYADIE
                     QFNAGNLVVRMTNDINQIQNVVMMTFQILFRLPLLFIGSFILAVQTLPSLWWVIVLMV
                     VLIFGLTAVMMGMMGPRFAKFQTLLERINAIAKENLRGVRVVKSFVQEKEQFAKFTEV
                     SDELLGQNLYIGYAFSVVEPFMMLVGYGAVFLSIWLVAGMVQSDPSVVGSIASFVNYL
                     SQIIFTIVMVGFLGNSVSRAMISMRRIREILDAEPAMTFKDIPDEELVGSLSFENVTF
                     TYPMDKEPMLKDVSFTIEPGQMVGVVGATGAGKSTLAQLIPRLFDPQEGAIKIGGKDI
                     REVSEGTLRKTVSIVLQRAILFSGTIADNLRQGKGNATLFEMERAANIAQASEFIHRM
                     EKTFESPVEERGTNFSGGQKQRMSIARGIVSNPRILIFDDSTSALDAKSERLVQEALN
                     KDLKGTTTIIIAQKISSVVHADKILVLNQGRLIGQGTHADLVANNAVYREIYETQK"
     gene            complement(63711..63980)
                     /locus_tag="VYO11_000327"
                     /pseudo
     CDS             complement(63711..63980)
                     /locus_tag="VYO11_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019770457.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            64172..65938
                     /gene="patB"
                     /locus_tag="VYO11_000328"
     CDS             64172..65938
                     /gene="patB"
                     /locus_tag="VYO11_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000859866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatB"
                     /protein_id="HEV1594940.1"
                     /translation="MKTVQFFWHYFKVYKFSFVVVILMIVLATFAQALFPVFSGQAVT
                     QLANLVQAYQNGNPELVWQSLSGIMVNLGLLVLVLFISSVIYMCLMTHVIAESTNEMR
                     KGLFGKLAQLTVSFFDRRQDGDILSHFTSDLDNILQAFNESLIQVMSNIVLYIGLILV
                     MFSRNVTLALITIASTPLAFLMLIFIVKMARKYTNLQQKEVGKLNAYMDESISGQKAV
                     IVQGIQEDMMAGFLEQNERVRKATFKGRMFSGILFPVMNGMGLINTAIVIFAGSAVLL
                     NDKSIETSTALGLIVMFAQFSQQYYQPIIQVAASWGSLQLAFTGAERIQEMFDAEEEI
                     RPEKAPTFTKLQESVEISHIDFSYLPDKPILKDVSISAPKGQMTAVVGPTGSGKTTIM
                     NLINRFYDVDAGGIYFDGKDIRGYDLDSLRSKVGIVLQDSVLFSGTIRDNIRFGVPDA
                     SQEMVEVAAKATHIHDYIESLPDKYDTLIDDDQSIFSTGQKQLISIARTLMTDPEVLI
                     LDEATSNVDTVTESKIQHAMEVVVAGRTSFVIAHRLKTILNADQIIVLKDGEVIERGN
                     HHELLKLGGFYSELYHNQFVFE"
     gene            66077..66766
                     /locus_tag="VYO11_000329"
     CDS             66077..66766
                     /locus_tag="VYO11_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HEV1594941.1"
                     /translation="MARTVVGVAANLCPVDAEGKIIHSSVSCRFAEIIRQVGGLPLVI
                     PVGDESVVRDYVEMIDKLILTGGQNVHPQFYGEKKTVESDDYNLVRDEFELALLKEAL
                     RQNKPIMAICRGVQLVNVAFGGTLNQEIEGHWQGLPFGTSHSIETVEGSVVAKLFGKE
                     SQVNSVHRQSIKDLAPNFRVTAIDSRDQTIEAIESIDEHRIIGLQWHPEFLVNEEDGN
                     LELFEYLLNEL"
     gene            66770..66949
                     /locus_tag="VYO11_000330"
     CDS             66770..66949
                     /locus_tag="VYO11_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1594942.1"
                     /translation="MEHLVVLSFIFSKFLECGILRKRLNSDKNWRNSTKKLEKNEGKR
                     YDRKEEILEEEHVTY"
     gene            66936..68285
                     /locus_tag="VYO11_000331"
     CDS             66936..68285
                     /locus_tag="VYO11_000331"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HEV1594943.1"
                     /translation="MSHIKFDYSKVLDKFVAPHEVEYMQSQVTAADELIRKGTGAGSD
                     FLGWLDLPEKYDREEFDRILKAAEQIKSDSDVLVVIGIGGSYLGAKAAIDFLNHHFAN
                     LQTKEERKAPQILYAGNSISSTYLADLVEYVADKDFSVNVISKSGTTTEPAIAFRVFK
                     ELLVKKYGQEEANKRIYATTDRQKGAVKVEADANGWETFVVPDDIGGRFSVLTAVGLL
                     PIAASGADIKALMEGANAARKDYTSDKISENEAYQYAAVRNILYRKGYATEILVNYEP
                     SLQYFSEWWKQLAGESEGKDQKGIYPTSANFSTDLHSLGQFIQEGTRIMFETVVRVDK
                     PRKNVLIPTLEEDLDGLGYLQGKDVDFVNKKATDGVLLAHTDGDVPNMYVTLPEQDAF
                     TLGYTIYFFELAIALSGYLNAINPFDQPGVEAYKRNMFALLGKPGFEELSKELNARL"
     gene            68409..69869
                     /locus_tag="VYO11_000332"
     CDS             68409..69869
                     /locus_tag="VYO11_000332"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HEV1594944.1"
                     /translation="MSKDIRVRYAPSPTGLLHIGNARTALFNYLYARHHGGTFLIRIE
                     DTDRKRHVEDGERSQLENLRWLGMDWDESPESHENYRQSERLDLYQKYIDQLLAEGKA
                     YKSYVTEEELAAERERQEVAGETPRYINEYLGMSEEEKAAYIAEREAAGIIPTVRLAV
                     NESGIYKWHDMVKGDIEFEGGNIGGDWVIQKKDGYPTYNFAVVIDDHDMQISHVIRGD
                     DHIANTPKQLMVYEALGWEAPEFGHMTLIINSETGKKLSKRDTNTLQFIEDYRKKGYL
                     PEAVFNFIALLGWNPGGEDEIFSREELIKLFDENRLSKSPAAFDQKKLDWMSNDYIKN
                     ADLETIFEMAKPFLEEAGRLTDKAEKLVELYKPQMKSVDEIIPLTDLFFSDFPELTEA
                     EREVMTGETVPTVLEAFKAKLEAMTDDEFVTENIFPQIKAVQKETGIKGKNLFMPIRI
                     AVSGEMHGPELPDTIFLLGREKSIQHIENMLKEISK"
     gene            69883..70317
                     /locus_tag="VYO11_000333"
     CDS             69883..70317
                     /locus_tag="VYO11_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HEV1594945.1"
                     /translation="MDIWEKMYEEAQKLYNPHEVSDFVYANHVVAAVEAGDGQIFTGF
                     CMEGTCGVFHLCAERAALFNMYQFSGQTKVKKVLAFRDKPPYGGSSAMPCGACREFLL
                     EFNAENKDAEFMMDYNIRKTVKVAELIPYWWGEERASKFNER"
BASE COUNT        20731 a        12996 c        15101 g        21555 t
ORIGIN      
        1 ttacagtttc tggtcaatgg tactatacct ataattcagg agatttatta gtaaacacga
       61 ctacacccga tggctatcga gtcaatgcta acggtgagtg ggtaggatag gtatccatta
      121 gctaaatcta atcattctga actaaaaaat cttcttacat atgtaggaag attttttgga
      181 ttctcaaaac tagtttaaaa gactacgcta tttaaaccaa ttttaagaat ggatatataa
      241 ggatattcag aaatctagtt ggtcaacttt tgtattttga atatacctta gatggtgacg
      301 atgtcttggt atatctggta ctcacttaca tattctaact tattttaact aagatacaac
      361 tgtagttggt gaatttgcta caaatagtgt agaggcgtta tttgaaaaat atacaaaaaa
      421 ggaaccccaa cttacatttg agtttctctt acttttaatc gtccgaatcc gtattcttat
      481 ttcaaaaaat gtagtcattc gaatgatttc tcttgcaata tagtgaaatt aacaaaaaga
      541 aaaaacgctg atcaagcgtt tttcttctgt attgattcgt attgaatgct tacttcactt
      601 ctgtaaacac aacgtgtttg cgaagttttg gtgagtattt cttcaattga aggcggtctg
      661 gagtgttacg tttgttttta gaagtaaggt acaagcgttc accagattct ttgtgttcaa
      721 gtgtaatatt tacgcgcatg gtatctccct tctattattc agctgatgca gctttagcga
      781 ttttacgtcc tttgtagtat cctttaagtg atacacggtg agaacgtgag taatctccag
      841 tagtttcgtc aaagtttaca gatggagctg ttactttgta gtgtgtacga cgtttgtttt
      901 tcttcgcttt tgaagtgcga cgtgcaggta ctgccatttt gatttctcct ttaggtattt
      961 atattcgatt caatctactg attttcatca accatactag gataacacat tttttttgta
     1021 aagtaaagtt acttgacaaa aaaagatgaa aaaattctcc tatccgacac ggcagacagg
     1081 agaaggtgtt aaatatcaat ctcaaatggt tcgtcaatgg tttctgatac gtattttccg
     1141 tctttcttcc gttgcttgac acactctgtg aggagatatt cgatttgccc attgactgaa
     1201 cgaaagtcgt cttctgccca tgatgcgagt gcagcgtata actttgttga gagtcgaagg
     1261 gggatctgct ttttttagct tcagccatct ttagtaaagg cttcctgtgt tgacaattgg
     1321 ttgtgcatca tgattgccac aaagaacgac aaggagattt gaaaccatgg cagcttttcg
     1381 ttcttcgtca agttctacca attcccctta tcacattgca atgaaagata ttctttgtag
     1441 ttatcaacgt tgaagactgc cttagcggta tcgacaactc tccaagttac cgcgataccg
     1501 atttctacag ggtttcctaa gcaatcattg attttttgac gagaattgct caaggtcatg
     1561 actttgaggg aaatctgttt cttgccaatt tcaagattta catcattgtc atttgatgat
     1621 ttagctccta aaaaaggaga ttttgtgcta acatcaccac tttgtccaag tcgagtgtgg
     1681 tttgcagggt tgactgctac gctgaaggga ttgacaaagt aaaaaccagg ttctttgatg
     1741 gtacctgtat aattaccaaa gagtgtcaga accagagctt cctgaggttt gacaactttt
     1801 aaaccagcat gagctagacc tgcaattacg attagtaaag gtccgataat aattccaaaa
     1861 atgttttccg aaccaacacc cattataaat ataaagatac caagtacgat tgtcaactca
     1921 atgagaatca atgcgaatac accatttggt tttgaattga ttagtttttc agtcataaga
     1981 atgacctccc attatttgat atctaaatga tatcactttg tttttaaaag tcaatagaaa
     2041 gttgaaaata atcactaaaa actttcagcc caataatttc ttttaaaagg tgagattata
     2101 ttgtgctcaa atactctttt attcttataa tttttacact ataattgtag ttagaaagga
     2161 agagaaatgt ttgattatag agcactagtt attttgatga ctttgatgga tcattgtgag
     2221 ctatcattat atgaattatc tgttaaggtg agcttaccta taaaggaagt caaagaagga
     2281 atagattatt tagtgcctta tctagctaat aaagggatag tgctggataa aaaacaaggt
     2341 cgctatagtt tatcaaatcg tacgaagcag tctttgacag atattattaa gtcggatgaa
     2401 ttggttttac caaagtcgac tcgcttagct ttaatctatc tttacacttt ttgccgatta
     2461 gattttatat cgaataatca ttaccaagac tttttgaaag taagtaagaa tacaacctta
     2521 tctgatattc aatcattaag aaagattatg ttagataatg atttggagct agggtacagt
     2581 agagcaaaag gttatacttt acacggttca gagtggaata agcaccgttt agcttttcaa
     2641 atggttagtg agttgctgga atcctccata gggatttggg gtttggatta tgttttatcc
     2701 agttgggggt attcattaac ttatgatttg attgatcagg tagttaaaga ttattatgag
     2761 aagctacagc tagtacctat tgttaatcaa ttaaaagttt accttttcgg tttagtattc
     2821 attctgtgta ggtatcaaag ggatgttgaa agagtatgtc tttcagagac attagtatct
     2881 cctgttattc aagatataac gactatttta ttggatacag tggttgattt gggaattata
     2941 gatacggtgt tttctgagga tgattatcgc tatatcaccg ttttattatc aagttgcttt
     3001 gaaggtgaag tagatgttgc tccggtttac tttaatcaat taacagaggc tattataagt
     3061 agaatggaag atatttcttt gttacatttt aaacaaaggg aaggattgag agaaaatctt
     3121 cgccgccacc ttataccggc ttactataga ttaaagttcg gcctacctag ttcaaatgaa
     3181 tatgtattgc atgttaaaga acattatcct gatttatttg aattagtcaa agattctttg
     3241 atgcccttga tggacgctat tgacaatccc atacctgata gtgaaacagc atattttgtt
     3301 atccatttcg gaggttattt aaagaaagca gatactttgc ctcaaaaatg ctataaagca
     3361 gcaatcattt gtcctaatgg tgttagttct tcattgatgt taaaagagaa tctattagca
     3421 ttatttcctc aaattgagtt tataggaacc tcaaagattg atgatttaca ggtgaaagtt
     3481 agtagtgact atgatatggt tttttctacc ataaaggtgg agacagaaaa gccaaattat
     3541 ctagtttcgg ttatgatgac tgaagagcaa gcaatacaac tagtagaact agtgttaaaa
     3601 gattttccga atttagagta tggagatttt gagattgaac aaatcctgaa tattgtcaaa
     3661 agatatggaa ttattacaca agaattggaa ttaagattgg cgttaaagaa ttatctttat
     3721 caaaaaaatg atagaaagga aattgtacca gtgctagaac aacttattac caaagaaacc
     3781 tatcaggtta gttcgcaaaa attaggatgg aaggaggcga ttcgtttagc agctaaaccg
     3841 cttttggatc aagataagat aactgagaac taccctgagg caatgattca aaaagtagaa
     3901 gagtttggac cttttattaa tttagggaag ggagtagcaa ttcctcacgc tcggccagat
     3961 gaaggtgtga atgaaatagg aatgtcaatg ttagttttgg aagaaccgat ttatttattg
     4021 gataatccag aacaagaggt aagattgttg atttgtattg cagccattga taatgagagt
     4081 catttaaagg ctttgtcaca tttaacaata attttaagag ataaaaatca tgttcaaact
     4141 ttaatatcat caaaaaacta tgatgacatt aaaatgataa ttaaacagga ggattagata
     4201 atgttaaaaa ttggtacagc ttgtggttca ggattaggtt caagttttat ggtacagatg
     4261 aacattgaat ctgtattgag tgatttgaat gtttcggatg tagaagttga acattatgat
     4321 ttaggtggag cagatccaaa tgcagctgat atttggattg ttggtcgtga tctagctgat
     4381 tcagctagtc atcttggaga tgttcgtatc ttaaatagta ttattgatat ggatgaacta
     4441 cgagaattaa ttactaaact ttgtgaagaa aaaggactta tataggaggc tagcgtcatg
     4501 atgaagttca tattggatat tgttagtaca ccagctattt tagtagcttt aattgcaatt
     4561 ttaggattag ttcttcagaa gaagaaatta cctgatatta ttaaaggtgg aattaagacc
     4621 tttgttggtt tcttagttgt atctggtggt gcaggaattg tacaaaattc tttaaatcca
     4681 tttggtacca tgtttgagca tgcttttcat ttatctggcg ttgtgccgaa taatgaagca
     4741 attgtagctg tagctttaac aacatatggc tcagctactg caatgattat gtttgcaggc
     4801 atggtgttca atatcttaat cgctcgtttt actcgattta aatatatttt tttaacaggg
     4861 caccacactc tatatatggc gtgtatgatt gcggtcattt tatcagttgc tggctttact
     4921 agcttgcctc ttatcttact aggaggatta gcactcggta ttattatgag tatttcccca
     4981 gcatttgtgc aaaaatatat ggttcaatta actggaaatg acaaggtggc tttaggtcat
     5041 ttcagttctt tgggatattg gttgagtggt tttactggta gccttatcgg tgacaaatca
     5101 aaatcaacag aggacattaa atttccaaag agtttagctt ttttacgtga tagtactgtt
     5161 agtatcactt tatctatggc agttatttac attattgtag ctatctttgc agggtcagaa
     5221 tatatagaaa aagaaatcag tagtggtaca agtggtctag tttatgcttt acaattagca
     5281 ggtcaatttg cagcaggggt atttgttatt ttagcaggtg ttcgccttat tttgggcgaa
     5341 attgttccag cctttaaagg tatttcagag cgtcttgtac ctaattccaa acctgctttg
     5401 gattgtccga ttgtttatac ttatgcacct aatgcagttc taattggatt tatctctagt
     5461 tttgttggtg gtttagtaag tatggtaatt atgattgctt caggaacggt tgttatctta
     5521 ccaggtgttg tacctcattt cttctgtgga gcgactgcag gtgtcattgg gaatgcatct
     5581 ggtggtgttc gtggagccac tattggagca tttttacaag gtattttaat cagttttctt
     5641 ccagtctttt taatgccagt tttgggagga cttggtttcc aaggatcaac tttctcagat
     5701 gcagattttg gtctatcagg aattatttta ggaatgttaa atcaatttgg ttcacaagca
     5761 ggcattgtga ttggtcttgt tcttattcta gcagttatgt ttggagtatc ctttattaaa
     5821 aagccatctg caaaggagga ataagggatg attttaagta aaaatagaga agatgggtta
     5881 agaaaatttg cgactaacat ccgattaaat actcttagaa cattgaatca tcttggcttc
     5941 ggacattacg gaggaagtct gtctatcgta gaagttttag cagtgcttta tggtgaaata
     6001 atgccaatga ctccagaaat atttgcagca cgagatagag attatttcat attatcaaaa
     6061 ggtcatggag gaccagctct atacagtaca ctctatttga atggtttctt tgacaaagaa
     6121 ttcttatatt ctttaaatac aaatggaacc aaattaccgt ctcatcctga tagaaatcta
     6181 acgccaggca tagatatgac aacgggctct ttaggacaag gaattagtgt tgcaactgga
     6241 cttgcatatg gtcagagaat aagaaagagt cccttttata cttatgctat tgttggagat
     6301 ggtgagttaa atgagggaca atgttgggag gctatacagt ttgcttctca tcaacagtta
     6361 tccaacttaa ttgtatttgt tgatgagaac aaaaaacaat tagatggttt tacaaaggat
     6421 atttgtaatc caggtgattt cgtagaaaaa ttttcagcat ttggatttga atccattagg
     6481 gtcaagggtt cagatattag agaaatttat gaagggattg tccaattaaa acagtcaaat
     6541 aattcatcac ctaagtgcat tgtattagat actattaaag gtcaaggggt tcaagagctg
     6601 gaagaaatga aatccaatca tcatcttcgc cctactgtag aggagaaaca aatgttaact
     6661 tcagttgtag aaagattaag tcaggaattg gaggaaacag aatgatgaga agtacgaaag
     6721 aattacggca tgtatataga gacttccttt tagaggctaa tcaaagttat tctgatatag
     6781 tagtcttaga agccgatttg tcaagttcga tggctactca taatcttgaa aaggactttg
     6841 gagaccgtta tgtgaatgtt gggattatgg aagcagaaat ggtcggcctt gcagcaggct
     6901 tgtctattca ggggtttaga ccttatcttc atacatttgg tccttttgct tcacgaagag
     6961 tatttgatca attatttatt tctcttggat acgcacaatt ggatgccact gtgattggat
     7021 cagatgcagg agtaactgca gaaatgaatg gtgggacaca tatgccattt gaagaaattg
     7081 gattgttacg tttaattcct aaatcgatca tttttgaagc aactgatgat atccaatttc
     7141 gtgaaatatt gaaccagaca ttagacttaa aaggactaaa atatattcga acaattagaa
     7201 aagctccagt tcctgtgtat caaggtggag aagatttttc taaaggctac attgagttaa
     7261 gacacgggga agattttgta atcgttgctt ctggtataat ggttgctcca agtattcgag
     7321 ttgcagatga actgtctaaa ttaggttatt cagtaggtgt gatagattta tttagaatca
     7381 aaccgatacc agaacagata aaaacaatgt taagtggaaa aactatattt actgtagaaa
     7441 accacaatca gataggtgga attggcagtg ctttatgtga attattctct gatgatggaa
     7501 taacaaaaat tcatcggatg ggggttcaag aaagattcgg tcaagtaggg aaaatggatt
     7561 atcttcttaa tgagtatggt ttgagtgaat cgaatataaa agagaaggtt ctagaaattt
     7621 ataatgcaag atagatgtta aatacactta tctgaaagaa tttctgtaaa aattacagta
     7681 cgttatttaa agaaagcgga ttaaaaagca tattctggtc atcagaaagt gcactaatcc
     7741 gctttgttgt ttttaatttt aaatatttca catgcgtata gaattttctg aaaattcaag
     7801 aattttattc tgttcattgc ctttaaattg tgctataata gtaaaaactg aaatgggagg
     7861 gataagatga ctgaattaga taaacgtcac cgcagtagca tctatgacag catggttaaa
     7921 tcacctaacc gtgctatgct tcgtgcgact ggtatgacag ataaggactt tgaaacatcg
     7981 attgtgggag tgatttcgac ttgggcggaa aatacaccat gtaacattca cttgcatgat
     8041 ttcgggaaac tggctaaaga aggtgtcaaa tctgcaggcg cttggcctgt acagtttgga
     8101 accattaccg tagcagacgg gatcgctatg ggaacgcctg gtatgcgttt ctctctaaca
     8161 tctcgtgaca tcatcgcgga ctccatcgag gcggctatga gtggtcacaa cgtggatgcc
     8221 ttcgtcgcta tcggtggctg tgacaagaac atgcctggat ctatgattgc tattgctaat
     8281 atggatatcc cagctatttt cgcctatggt ggaactattg caccgggaaa tcttgatggt
     8341 aaagatatcg acttggtttc tgtctttgaa ggtatcggaa aatggaacca cggtgacatg
     8401 acagctgagg acgtgaaacg tcttgaatgt aatgcctgcc ctggccctgg tggttgtggt
     8461 ggtatgtata ctgctaatac catggcaact gctatcgaag ttctagggat gagtttgcca
     8521 gggtcatcct ctcacccagc tgaatcagct gataagaaag aagatatcga agcagcagga
     8581 cgtgctgttg ttaagatgtt ggaacttggt ctcaaaccat cagatatctt gactcgtgaa
     8641 gcctttgaag atgctattac tgtaacgatg gctctcggtg gttctacaaa cgccactctt
     8701 cacttgctcg ccattgccca tgccgcaaat gttgacttgt cacttgagga cttcaatacg
     8761 attcaagaac gtgtgcctca cttggccgac ttgaaaccat ctggtcagta tgtcttccaa
     8821 gacctctacg aagtcggtgg tgtccctgcg gttatgaagt acttgttggc aaatggtttc
     8881 cttcacggag atcgcatcac atgtactggt aagactgtag ctgaaaactt ggctgacttt
     8941 gcagacttga ctccaggcca aaaagttatc atgccacttg aaaatccaaa acgtgcggat
     9001 ggtccgctta tcatcttgaa cgggaacctt gctcctgacg gtgcagttgc caaggtatca
     9061 ggtgttaaag tgcgtcgtca cgttgggcca gctaaggtct ttgactcaga agaagatgcg
     9121 attcaggccg ttctgacaga tgaaatcgtt gatggcgatg tagtcgttgt tcgttttgtt
     9181 ggacctaaag gtggtcctgg tatgcctgag atgctatcac tttcttcaat gattgttggt
     9241 aaaggtcagg gagataaggt ggccctcttg acggacggac gtttctctgg tggtacttat
     9301 ggtctggttg ttggacatat cgctcctgaa gctcaggatg gtggaccaat tgcctatctc
     9361 cgtaccggcg atatcgttac ggttgaccaa gataccaaag aaatttccat ggccgtatcc
     9421 gaagaagaac ttgaaaaacg caaggcagaa acaaccttgc caccacttta cagccgtggt
     9481 gtcctcggta aatatgccca catcgtatca tctgcttcac gcggagccgt gacagacttc
     9541 tggaatatgg acaagtcagg taaaaaataa actcatactc gaaaatctct tcaaatcacg
     9601 tcaacgtcgc cttgccgtag gtatggttac tgacttcgtc agttctatct acaacctcaa
     9661 aacagtgttt tgagctgact tcgtcagttc tatccataac ttcaaaacag tgttttgagc
     9721 agcctgcggc tagttttcta gtttgccctt tgattttcat tgagtatcaa aaagcaagcc
     9781 attttcggct tgcttttttc atctttaaaa gtgattggcc tgcttaacga ggtggtagtc
     9841 caagggcaat acggccatag cgactgattc gtgtgatttt ccaagcaggc gaccaggtaa
     9901 cttcaacctt gatatctttg ataccctcga tttgtttcag acctgccacg atttcaatag
     9961 gtaggctttc ggcgcaatca caggcagtat cggtgaaggt catgacaatc ttgcagagcc
    10021 ccgtttcatc cagattgatt tcataaatca gacctagatt gtaaacatcc aattccacat
    10081 ctgtatcaaa aactttctct agtttttcga taatttggtc ttgcaaggcc aaagcacggt
    10141 cattgatttt gatatcgtct ctcatagcag tccctccacg tgataaatat cctctatttt
    10201 ctcataattc tgacaatttg gcaagttttt gatgaatttt ctgaaaaata tgataaaatg
    10261 aagaaaatac ggaatcaagg ggaagtctat ggagcagatt ggaaaagtct ttagacaatt
    10321 acgagaatca agaaatatct cactgagaca agcaaccgga ggacaatttt cgccgtctat
    10381 gttgtcccgt tttgaaacag gtcagagtga gctttcggtg gaaaagtttc tatttgctct
    10441 ggaaaatata tctgccagtg tggaggagat cctctttctg gcgagaggtt tccagtatga
    10501 tacagattct gagttgagaa aagaaattac agatgtcttg gaaccaaaga atatagcacc
    10561 tcttgaggac ttatatcgca gggagtatca aaagcatgcc cattctcaca acaaacagaa
    10621 acatattcta aatgccatta tgatcaagtc ttatatgaag agcatagatg aaagggtaga
    10681 cttaacagca gaggaaggaa aagtccttca tgattatttg ttttctaccg agatctgggg
    10741 aatctatgaa ctcaatttat tttcagtcag ttctccattt ttatctgttt ctctttttac
    10801 tagatatgta cgagaaatgg tacgtaaatc tgattttcta atggaaatgt ctggtaatcg
    10861 aaactttttt catactatac tattgaatgg ctttttagct agtattgagt gtgaagaatt
    10921 taccaatgcc tcttatttta aacgtgttat cgaagagcat ttctacaagg aaaatgagac
    10981 ctatttccga attgtttatc tgtgggcaga aggtctcctt gatagcaagc aaggtagagt
    11041 caaggaaggc cagaaaaaga tggaggatgc tgtccgtatt tttgagatgc ttggctgtaa
    11101 taaatctgcc gaatactata gaaatacgac cgaatgttga atatctgcaa actaagaaaa
    11161 aatttgaagc gatagaactg ttgccctttc tcaggtcatt acaaaagttc tatcgttttt
    11221 ttgctcattt tatttgttgc atatattcaa aagaatcgtt tcgcaaattc ataagtgcta
    11281 tactaaagct attcttgatg tagaacttag aacaaggagg gagattatct atgaaactat
    11341 tgtttagaaa tcaagcttat cgcctattga ctttgtcacg cttcttcaat gcttttggtg
    11401 cttcgatttt caacctggtc tttatcgtct atgcatcgac cttgtcacaa gcatcttttg
    11461 ctgttgctat ggcgaatatt gtcatgattc ttccgaccct ctttacagtt tttgcaggga
    11521 ttcgggcaga ttacacgagg gacaaggtca aatggatggt ctatagcggt ttgtttcagg
    11581 cggttctatt ttttctagca gccctagttg ttcagcaagc tagtctcttt gccttttcta
    11641 gcctgtgttt gatcaatgtc attagtgatg tcatcagtga ttttgcaggt ggcctgcgta
    11701 tgcctcttat taaggaaaaa gtagctgaag atgatttgat ggaggcttat tctttttcac
    11761 agttcatcac ctatatttca gctattggtg gtcaagcttt cggagtctgg ctcttagctc
    11821 tatcggtcaa taatttttct ctcgttgcgg gaatcaatgc ctgctttttc ctagtatcag
    11881 ccactatcct ctttttagga aaaagcaaat tgagcctgtc aatgtcattt gctgatggtg
    11941 aaaacttaaa aaatgagaag ctttctatca aagaccagtt cctaacaatt taccgaaatt
    12001 tacgtctcgt ttttcttaaa agtggacaga aaaactttgg ttttatgctc tttgctgtct
    12061 tgcttattaa ttccttgggt ggcgctttgg gtggaattta taatatcttc tttttgagcc
    12121 attctctctt gaatttttct tatacagagg cactatttat caatcaattc tgtgttttag
    12181 tagcaatcat catcagtagc cttacgggca atgattattt tgggaagcaa tccttgccta
    12241 gattgatgat gtgggagacc gtaggactta gtctagttgg tttggctaat ttattcaatc
    12301 aagtcgtgct tggtttgcta tttctcttct ttactctgta tgtgtctggt aaagttcaac
    12361 caaagattag tgccatgctc atgaaaaatc tagctccaga ggttctagct cgtactagta
    12421 attttttcgg tctattgttt accttatcca tacctgtggg aacagcttgt ttttcactag
    12481 tagccgtatg gaatatacag ttgacttgga tgctatttgt tggtctttcc ttgctagcta
    12541 tttttttgac aattcttaat ctcaaaaatg atatctaaat cctaattttt ttcttactgt
    12601 tttaatccct ttatttgtgg taaaataaga ctattaagtt taaagaggat tccctatgaa
    12661 attacaaaaa ccaaaaggaa cgcaggatat tttacctgct gaatctgcta agtggcagta
    12721 cgttgagggc tttgcccgtg agattttcaa gcgctataac tatgcagaag tgcgcacgcc
    12781 tatttttgag cattacgagg ttatcagtcg ctctgtcgga gatacaacgg atatcgtaac
    12841 caaggaaatg tacgattttt atgacaaggg tgaccgtcat attaccctcc gtccagaagg
    12901 aactgcgccc gttgtccgtt cctatgtgga aaataaactc ttcgccccag aagtgcaaaa
    12961 gccaagcaag ttctactata tgggacctat gttccgttat gagcgtccac aggcagggcg
    13021 cttgcgccaa ttccaccaga ttggtgttga gtgttttggc tctagcaatc cagctaccga
    13081 tgtggaaaca atcgctatgg cagcccattt tttgaaggaa atcggtattc aaggtgtcaa
    13141 attgcacctc aacactcttg gaaatcctga gagccgtgca gcctaccgcc aagccttgat
    13201 tgactatttg acaccgctca aggagacctt gtctaaggat agccaacgtc gcttggagga
    13261 aaatcctctt cgtgtcttgg actctaagga aaaagaagac aaggtggcag tagagaatgc
    13321 gccgtctatc ttggactttc ttgatgaaga aagccaagct cattttgatg ctgtgcgtca
    13381 gatgttggaa aatcttggag tagattacat catcgatacc aatatggtgc gtggtctgga
    13441 ctactacaac cacaccattt tcgagtttat cacagagatt gagggcaatg acctgaccgt
    13501 ctgtgcgggt ggtcgttacg atggtttggt ttcttatttt ggaggccctg aaactgctgg
    13561 atttggtttt ggacttggtg tagagcgcct gcttctcatt cttgaaaagc aaggtgtgac
    13621 cctccctatc gaaaacgccc tagatgtcta tatcgcagtc ttgggcgaag gggcaaatat
    13681 caaggccttg gaattggtac aggctcttcg ccaacaaggt ttcaaagcag agcgtgatta
    13741 cctcaaccgt aagctcaaag ctcagttcaa gtcagcagat gtctttgcgg ctaagaccct
    13801 catcacccta ggagagagcg aagtcgaaag cggacaagtg acggtcaaga acaaccaaac
    13861 ccgagaagaa gtgcaagtgt cacttgagac aatcagccaa aacttctcag aaatctttga
    13921 aaaactagga ttttatactc aatgaaaatc aaagagcaaa ctaggaagct agccgcaggt
    13981 tgctcaaaac actgttttga agttatggat agaactgacg aagtcagctc aaaacatggt
    14041 tttgaggttg tagatgaaac tgacgaagtc agtaaccata cctacggcga ggtgaagctg
    14101 acgtggtttg aagagatttt cgaagagtat taatgataga taaactggtc agtaacctac
    14161 tcctgacctt tttcttttgc aaaatgacaa aaatcataaa ctttttgaca actatacttg
    14221 tcaaaaagaa aaagatatgt tacaatgaat tcaagttaag aaataggaag cagaaaggag
    14281 ttataatgtg ggtactagga tttatactat ttatgatttt cttttattct aataattcta
    14341 aaaaaatcaa gaaactagag aataaaatca aaaaacttga gcgaaaagag aaaggaaacg
    14401 cagaaatgtc gagattatta caagaaatga ttggaaagga accaattata acgggagtgt
    14461 atattgggcc agataactgg gaagttgtgg atgttgatga ggaatgggta aagctacgac
    14521 gtgtagataa tacgggaaaa gaaaaattca agttgcaacg tattgaagat atccaaaccg
    14581 ttgaatttga cggagagtag gtgtgtaacg tgcaactaaa aaatcgtcta aaagagcttc
    14641 gagctcgcga tggtctcaat caaaccgacc tagccaaact ggcaggggtt tccagacaga
    14701 ccattagcct actagaacgg gatgagtaca ccccatccat tatcattgcc ctgaaaatat
    14761 ctcaaatttt caacgaaaca gtcgaatcgg tatttcgttt ggaggaggac gagtgatgaa
    14821 caagtataaa gtgatttatt atgtagtggt catagcttta ttagtcagcg tatttctact
    14881 gattgggata gacctaagct ggtttaatcc ctattaaagc gaccaatttg tttgggtcta
    14941 ctttgctctc atcccagtaa ttgaatggat tgaaaagaaa tccaaaaatc tagcaagtga
    15001 aaaaggagaa tgaatatgaa aaagaaacgt agattgttat ttttgatgtc tattgtcttg
    15061 ggggggttct tgggcatgtt tgtagggatg tttaaggcac gtgtcgaatc ccacgaaatt
    15121 attttagatg taaaagcctt gatgccatgg atatcagcta tttgtttact gataggtttc
    15181 attagtatgt ttttgacttt caatttctta aagaaaagca gaaaatttca ttccttgtat
    15241 caagaggaaa tggatgacga tctgaatgaa acctattatg tgcaaatgta tcggaatctt
    15301 gagtttggaa ccattgcttt taatattaca ggtgtagcga ttccattggc tatttttatt
    15361 tcattaagtg aggtgattat attgcataca aaccctcaaa catttttcct ttctttctta
    15421 ctctttgtgg tattcttagt cgctcaaaaa tctcttttta aaaccattgc gattgttcgt
    15481 cagtttgatt tggaattttt cgctacacca aaggatgtct tgaactatat aaattcttat
    15541 gatgaagggg agcgtcaggc taatttggaa cagagttttc gaattttatt ccaattacac
    15601 caatatgtct taccagcctt atatattttt cttattatca tttctttctt gacaggagag
    15661 attcagttac tagctttctt gcttgtagga gccatccatg tttatatcaa tgtgatgcag
    15721 ttacctatgg taaaacgtta tttcaaataa aggagttatc tatgaaatta cttaaaaacc
    15781 ttggctggtt tcttctagcc cttctatcct ttttctttat ctatggcttt attcaggggc
    15841 tcgcgactgc gtcgcttgct ttaggcgctt caccctatgc tgttactcta ctctatgtgg
    15901 tcttggctgg agtatatgtg tacggcattt acaaatggta tcagaaagct cctgtttata
    15961 ttgagaagag cggctttaac cgatttattt ggcttcctgc cttggtttgg ttcttatctc
    16021 tggtcgttca attcttcttg ccagatgatc cttcagtaaa tcaacaaata gcgacagact
    16081 tgaccttgtc tcaaccactt ttctcattct ttgctgtggt tatttttgct cctttgacgg
    16141 aagagattgt ttttagaggg atgttagcac gctatctctt tcctaagcag gacaatagta
    16201 aacgaaccct gatttttctt ctggtatcta gtcttctatt tgccttgatt cattttccag
    16261 gtgatgtgca acaatttttt gtctatttta gccttggttt tagtttgggt ttggcttaca
    16321 ttagcagaaa aggtctggtc tacagtattt ctcttcacgc tttgaataat ttagtcggct
    16381 ttttgatgat tctcatgcta taatagagtc aggaggtcac atgaaacgag taattttatt
    16441 agcagtgatt caggcagtcg ttctattttt catcattgga gcgctagctt atgccttcaa
    16501 aggcgatttc ttctataact atctagcagt tgtctttgct cctattgcag gtgtactgcg
    16561 ttttgggacg gcttacataa cggaaattgt cttgcctcga aaggcagccg aaatcgctga
    16621 aaagcgtaaa gcaggcaaaa attcaaaata aaagagtccg gtgaagttca tcggattttt
    16681 gtattatact caatgaaaat caaagagcaa actaggaagc tagccgcagg ttgctcaaaa
    16741 tatggttttg aggttgtaga tgaaactgac ggagtcagta accataccta cggtaaggcg
    16801 acgctgacgt ggtttgaaga gattttcgaa gagtattagc gctaattttt agggctttca
    16861 cttgactttt aaagactggc aaacttttct gatgattttc atgaagagcc tgcgctttta
    16921 tggtaaaata gtaacagaat aaaagaggag agaaataatg aaacgtagta tgtatgctgg
    16981 tcgtgttcgt gaggaacaca tcggacaaga aataaccttg aaaggatggg ttggccgtcg
    17041 tcgtgacctt ggtggtttga tctttatcga tcttcgtgac cgtgaaggaa tcatgcagtt
    17101 ggttatcaac cctgaaaaag tatctgcaga ggttatggca acagctgaaa gccttcgtag
    17161 cgaatttgtt attgaggtga ctggtcaggt cgctgcgcgt gagcaagcca atgataagtt
    17221 gccaactggt gcggttgagt taaacgtgac agctcttatt gtgcttaaca cagctaagac
    17281 aacaccattt gagattaagg atggcattga ggcaaatgac gatacacgtt tgcgttaccg
    17341 ttaccttgac cttcgtcgtc cagaaatgtt ggaaaatctt aaacttcgtg ccaaggtgac
    17401 ccactctatc cgcaactact tggatgagtt ggagtttatc gacgtggaga caccattcct
    17461 ttctaagtca acgcctgaag gggcgcgtga ttatttagtg ccgtctcgtg ttaataaggg
    17521 gcatttttac gctcttcctc aaagtccaca aatcacgaaa cagctcttga tgaatgctgg
    17581 ttttgaccgt tactaccaaa tcgttaaatg tttccgtgac gaggacttgc gtggagaccg
    17641 ccagcctgaa tttactcagg tcgacttgga aacgtccttc cttactgagc aagaaatcca
    17701 agatattaca gaaggcttga tcgcgcgcgt gatgaaggaa acaaaaggca tcgaagtaac
    17761 gctaccgttc cctcgtatga aatacgatga tgctatggct ctttacggtt ctgacaagcc
    17821 agatactcgt tttgacatgt tgcttcagga cttgacagaa gtggtcaaag gtgtagactt
    17881 taaagtcttt tcagaagcac ttgctgtaaa agcgattgtg gtcaaaggag ctgcggacaa
    17941 ctattcacgt aaagacatcg acaagatgac ggaagtagcc aaacagtatg gtgccaaagg
    18001 tcttgcttgg gtcaaggtgg ttgatggaga attaaacgga ccagttgcca agttcttgac
    18061 tggtatccaa gaagaattga caacagcgct tgctcttgaa gataaggact tggttctctt
    18121 tgtggcggat acgcttgaag tggctaatgc aacactgggt gcccttcgtg gacgtattgc
    18181 taaagagctt ggcttgattg ataatgataa gttcaacttc ctttgggtgg ttgactggcc
    18241 gatgtttgaa tggtctgaag aagaaggccg ctacatgagc gcccaccatc cattcacact
    18301 tccacaggaa gagactgctc acgaattaga aggtgatttg gctaaggttc gtgccattgc
    18361 ttacgatatc gtcttgaacg gttatgagct tggtggtggt agccttcgta tcaaccaaaa
    18421 agaccttcaa gaacgcatgt tcaaggctct tggtttctca gctgaagaag ccaatgacca
    18481 gtttggtttc cttcttgaag ccatggacta tggtttccca ccacacggtg gtttggctat
    18541 cgggcttgac cgttttgtca tgttgcttgc tggagaagaa aatatccgtg aagtcattgc
    18601 ctttcctaag aacaacaagg caactgaccc aatgacacaa gctccatcaa cagtcgctct
    18661 caaacaacta gaggaactca gcttacaagt agaagaagat gaaacaaaca aaacgaatta
    18721 agcggtggcg ctattatctg cgccgctttg cttatcagat aaaaatttta cgtgtcttac
    18781 aaagtatctc tcgagaaaag tatgatgaga agatttcggc ctctctggtc tatggttttt
    18841 tatcagcagt agcagttaat ttctttttcc aaccagggca tgtgtattcg agtggtgcaa
    18901 caggtctggc acagattatc tctgccttga gtaatcactg gtttggtttt catattccga
    18961 tttcgctaag cttctacgcc attaacttcc ctttgatggt cttagcttgg tatcagattg
    19021 gccataagtt caccgtcttt acctttatca cggtatctat gagttccttc tttatccagt
    19081 ttgtccctgt ggcaaccttg acggaggatc ccattatcaa ttcccttttt gggggtgttg
    19141 ttatgggttt ggggattggt tttgctcttc gaaacaatat ctccagtggt gggacggata
    19201 tcgtcagcct gactattcgc aagaaaacgg gtaagaatgt cggtagtatt tctttcttgg
    19261 taaatggaac tatcatgctg atagcaggtt tgacctttgg ttggaaatac gctctttatt
    19321 ctatgattac catctttgtc tctagccgtg tgacagacgc agtctttact aagcaaaagc
    19381 gtatgcaggc catgattgtg acaaatcatc cagagaaggt aattgaaaaa atccataaaa
    19441 aattgcaccg cggagcaacc atgatccacg atgcagaagg aacctataat cacgagagaa
    19501 aggcagtttt aatcactgtc attacacgtg cagagtttaa tgaatttaaa cagattatga
    19561 cacaagtgga tccaagctcc tttgtctctg tctcggaaaa tgttcatatt ctaggaagat
    19621 ttgttgagat agataattag tgattaatac tcttcgaaaa tctcttcaaa ccacgtcagc
    19681 ttcaccttgc cgtatatatg ttactgactt cgtcagttct atctgcaacc tcaaaaccat
    19741 gttttgagct gacttcgtca gtttcatcta caacctcaaa accatgtttt gagctgactt
    19801 cgtcagttct atccacaacc tcaaaacagt gttttgagca acctgcggct agcttcctag
    19861 tttgcacttt gattttcatt gagtataaaa agatcttggg aaaagactca atttcagtag
    19921 aaaaggaagt aaatcttccc acaataaaac gcatagtatc aagttttttc aatacctgat
    19981 actatgcgtt tttgctttta acgacttttt acccagtctc ttatttttcg ataattttgt
    20041 gggcgatcaa ttgacggtaa caaatttgtt tattgttttt attatcatta ataatctgga
    20101 gaatagtttc aagggaaaca cgaccaagct ctaaactatt gatatcgaca taggctgcca
    20161 agttgagctt gggattaacc gagtcaaagc tgagaacagg gacatccagc tggtgtttgg
    20221 caatatagtt acaaacacct tcagctagga ggctatcggt tgtgatgata gcatcaattt
    20281 gtggatcgtg cttgaataat cgcttgctaa atttatagcc cttttcttcc agaaactcgt
    20341 cggcaaagta gatgcgattg ttgtcagtgg taagtttgta atgtttaagc gcctgttcat
    20401 agcctgttaa acggtctttg gtcacgaaga gctttttact tcctccgata aaggcaatgc
    20461 gtttgcagcc ttttttgatg aaatattcag tcgcatcaaa accagcttga acattgtcgt
    20521 tgtcgacaag tgggatgaaa ggagatagag atttacctaa gataaggaag gggaactgtt
    20581 cttctgcgac gagttttacg agagggtctt cttcttgggc atagagaaag attagcccat
    20641 ctacacgctt gccgtagacc atttgtgaaa tagcgttgag acgctccttc tcatctttcc
    20701 ctgttgctat ctgaatggca tagtggtttt cagatgcgac ttgagagatg ccacgtagaa
    20761 ccgatggaaa gaaaggattc tggtagaagg cgtctgagtc atcaggaaga actaatccga
    20821 taacctgagt atagctgctt accaagctac gagcgttgag gtttgggtgg tagttgagtt
    20881 ccttcatagc tttgcgaacg cgtttttttg tttcgtcgct aatggttgat ttattttgaa
    20941 taacacgggt tacggttgaa ggcgaaacac cagcagcctt ggccacgtct ttaatcgtaa
    21001 cgggcataaa aatctcctat ttatggtaat ttggatcacg gaaatgtgtt ttataaaaga
    21061 tagtgaccag atacagaaca aaaagaatat tttgtacagt aatcagggtt gtcatatttt
    21121 ggccaaataa tcccaaaata agtgtaatca gagtcggcaa tcctaaacag ttcaagataa
    21181 agtgatagca ctctttaaag gttctaaatg aaaagaggcg tgatttctta gtgatataaa
    21241 ggagaagact agctcctaga gagacgataa agaaattcaa accaaagagg aagctcgcac
    21301 cgagaactag gaagaggctg atatagacac gattttgttg gtaccagtct ttagaaattg
    21361 cttgggtcaa gctgtctttg cttttgaaac tctcagtctg aatggctcgg taagagatgc
    21421 gggtcagttc cttgctttcc ttgctgatga ctagctcatt tgtatcgaaa tgcagttgca
    21481 agtccttagg taattccttg atttgacttg gaccaatcac aacagaagga gcttgactag
    21541 ctgttccagt ataagttaat gtgccatcga caattgtagc atgttcagag agatcctgga
    21601 caacctcatt tgtcagaggt tcatagacat tatcgataaa agtttctagc ggataggtct
    21661 cctgggagct gttttggata gcaatgggta ccatagataa gctgataagg aagatactgg
    21721 taaagagaag ttgaaaccag ttgagctcga aacgtttgga caggggctta cgaaaccccc
    21781 aaatacttga aaaataggaa aatggatatg gaagcatagg tatctttcta aaaggtgttt
    21841 tctatatgag tattattata tagagaaatg cgctttattt caagtctagg agaaaaattg
    21901 cttgctacaa ggatattatt tacagtgaca attgctaata atcaatgaaa atcaaagtgc
    21961 aaactagcca caggttgctc aaagcacaac tttgaggttg gagataaagc tgacgtggtt
    22021 tgaagagatt ttcgaagagt ataaaatgaa aaagggtggc ggggataaat tatcccttgt
    22081 cgccaccact tgtaagtcct gaaacaaagt tcttttgtag gaagaagaag agaatacaga
    22141 ttggaagggc gatgaggata gcacctgctg agaagtaggc aatcttcaag tttttcgcat
    22201 tgttaacgaa ggtttggaga cctacggcaa cagtaaagta ttctttctca cgaagcaaga
    22261 aactagagag gatgtagtcc ccgaaaggtc ccatgaaggc ccagagagct tgtacggcaa
    22321 ccattgggcg aacaagtgga agaacaattt gccagaagcg gcggaagtgt cctgcaccgt
    22381 ctagttttgc agattcgtct aaagacattg gcactgtatc gaagtagcct ttcatgagcc
    22441 aagcattcat cgggatacca ccaccaacgt agaggaagat gaggaaccag ctgtggttaa
    22501 gggcgttcaa cataagcgcc ataacgaaga aggctgtcaa agcggccata gttggcacca
    22561 tttggatgat caagaagaag accaaacttt gtttacgagc caagaagttg taacggctgt
    22621 aagcataacc agcaagtacg atgatacttg tttgaacagc catggtaatt aaggcgataa
    22681 tcaaagtgtt gaggtaccaa gtaccgtaca aggtttcagt gaagaggcct ttaaagttat
    22741 caaaattgag gtcgatatta gtatctagtt taaaggctga gacgttacct gctttaaagg
    22801 ctgacataat ggtaatcaac agtggataga taattacaat tgatagacca atcaggtaaa
    22861 ggtaagtaag gctttgagtc agtctacgtt tgagtttaat tgagttattc atcttagacg
    22921 tcctccatat caaatgcgtg tagtttcttg aatgcgatca tagagattga gatgacaatg
    22981 atagagataa tcaaggtaac agctgccgcc attgagtatt gaggagatgt acctgttgtc
    23041 aaacggtaga tccatgagat caagatatcg gttgaaccag ctccacctcc gacactacca
    23101 ggtcctccac cattgaagag gtacatgata gagaagttgt taaagttgaa ggtgtattgg
    23161 ctaatcaaag taggtgccgc aacagccaaa atcattggga aagtgatgtt gcggaatttt
    23221 tgccaagcgt tggcaccgtc aatataagct gcttcgtaaa ggtcgttagg aatagattgc
    23281 aagataccca aagtcaaaac gtagatgtat gggaatccga gccaaccttg catcataatc
    23341 aaggcaatct tagtccaagt tgggtctgtt ttccaaggaa taagagctcc atcaaggaaa
    23401 ggaaggaatt tagccaagat tggcaatact tgagtgttga tagcaccgac actatcgtta
    23461 aacatgtttg agaatgtcaa gatagtgatg aaggctggga cagcccaagg aagaaggaaa
    23521 ataacaccaa agatacgttt tcctttgata aatggttggt tggcaatgat agctgtgaag
    23581 ataccaatta cgatttgtaa agtagaagct gccaaagccc aaatgatagt ccaagaaaga
    23641 acagaaccaa aggcagaacg gaaggtactc aagctccaaa tgtttgtaaa gttggtcaaa
    23701 ccaacccagt ccaacaactt gtttggtggc aagtgttgga agtcgtagtt ggtaaaggcg
    23761 atcatcaagg ttacgataac tgggaagata atcgcgaagg tcatggcaac ataagatgga
    23821 atgatcaaga ggtaagggaa gccattttca taaatccctt tgatcatgtc tttgagtgtg
    23881 cgtggaactg gaattccatt gttaatgcgt tttgcaatcg tatgtgcatc tttgatattt
    23941 gagaaataaa agagtacata aacgattaca aagattagat ggaaggcacc acgaatcagc
    24001 ataaagaggg aattatcacg acctggtttg tcaccaagag tgatgaggtt gctcaattca
    24061 ggggttgcaa gtgctaggaa gtaaaggaca aatacgatgg ttacaccaag gaagataaaa
    24121 cctttggctt tttgtttatt gtaaatctgt cctaacccag gaatgataga cagcagggct
    24181 gctttactag gttgttgctt ttccatatta actcctttca taggatacta cttttttata
    24241 agaaagctaa attatttgtg tctctattga taaattcaaa gggggatttg atttccaccc
    24301 cccttgaaca aattttttat tcaccaaatt tttgtttgat tgtttctttg atcaatgtta
    24361 cagcatcgtt agcagctgtt ttagcatctt tttgaccact tacagcatca aagagcatat
    24421 ttttcgctgg atcccaaact gcagacattt gagagatgtt tggcagtggt tgagtgttct
    24481 tgaactgttt gataacagct gttgtcaact catcgttttt accttcagcg tatgaacgag
    24541 cctcagtatt agctgggatt tcgttagtct tatcatataa tactttttgt tgttcagttg
    24601 caacaaggaa gtctacaaat ttttgagaag cttcaaggtt cttaacggct tgaggaatga
    24661 cccaagcttt accaccaccg aatgcagcat attcttttcc atttggaaga gttgggatag
    24721 ttgcaactcc gtagtttact ttagcatctt taaaggcttg agctttccaa ggtccgtcga
    24781 tgatagcagc tgttttacct tcttggaatt gagtttggat taagtttcca gcaccttctg
    24841 tatcttgcat acctttaggc catttttcgt accaagattt agcgtagttg atacctgcga
    24901 tagaaccgtc gtttgcaaga ccgatgtctt tagcgtcttt accgttttgg ccaaagacgt
    24961 aagcaccgtt accggcaaga agtccatatg tatagtagaa gtttgtccag tcagctagga
    25021 aggcagtagt tttaccatct tcaccagcga atgcgtattt gctatcttta gcaaggtttt
    25081 ccaagtcagc aaatgttttt ggagcatctt tcaccaagtc tttgttgtag tacataacaa
    25141 gtgactcgat aacggcagga gcaccgtaaa ctttaccatt agcagctgtt acaagagatt
    25201 tagttgtgtc gtctgtttta gcaccatcgc tcaatttcac ttctgaaagt tgtccgtcag
    25261 aaccaaggct acctacacgg tcgtatggag ccatcataac atcagggaca ttaccagatt
    25321 ggttgtcaag agaaagttta tcaagacctc ctagagcatc accagtttta agagtgactt
    25381 ttactccagc ttctttttca taagctttag caacctcttc aatatagctc ttatatccct
    25441 cgtctacata tacagtgagt tctttgactt cagatgaacc agaatcagca ggcttatcag
    25501 cagttttgct tccgcaagct accaaaagca agctagcaag tgtagcagtt ccaagcaccg
    25561 cagtgctctt cataaattta gatgacatag tgtattcctc ccaaagaata gcaagtttta
    25621 ttgataagga aacgcaaacg ttttccttta tgagcttagt atagcacaaa tagaaaacgg
    25681 ttgcaagtat tttttgtaaa aattttaaaa aatttttaag cttgatttga tagcataatt
    25741 ttacatttta atagaagaaa agtatgaaat agataagaat acagtatttt taataaaaat
    25801 atatggaatc tgtctaaaga gggaaatcag gaggggctac ctccctgttt ctaatcccta
    25861 tctattttct atagacgttt gtgctttgtt gcatataaat tcaagctccc taaggaggtt
    25921 ttgtactttg tagactgtct cgtgagagtc aaactttagg attagatagt tttaagttat
    25981 ctttgctaaa atgagttagt ctccttaaaa ataatcaaaa aagtttttta aaaacgcttg
    26041 caattatgct tgaaaaggag tatacttata agtaacgcaa acgtttgcgt ctgaaaaata
    26101 cgcaacgttc cattatttta acacacgagg tgctattatg aaaaaacgtc aaagtggtgt
    26161 gttgatgcac atctcttctc ttccaggagc ttacggaatc ggatcatttg gtcaaagtgc
    26221 ttacgacttc gttgatttct tggtccgtac aaaacaacgt tactggcaaa tccttccatt
    26281 aggagcaact agttacgggg attctcctta ccaatctttc tcagccttcg caggaaacac
    26341 tcattttatc gatttagata tcttggtgga gcaaggtttg ttggaagcaa gtgaccttga
    26401 aggagttgac tttggtagcg atgcgtctga agttgactat gctaaaatct actatgcacg
    26461 tcgtcctctt ttagaaaaag cggtgaaacg tttctttgaa gtcggagatg ttaaagattt
    26521 tgagaaattt gctcaagaca accaatcatg gcttgagctc tttgctgagt atatggctat
    26581 caaagagtat tttgacaatc ttgcttggac tgaatggcca gatgcagatg ctcgtgctcg
    26641 taaagcttca gcacttgaaa gctatcgtga gcaattggca gacaagttgg tttaccaccg
    26701 tgtgactcaa tacttcttct tccaacaatg gttgaaattg aaagcttacg ctaacgacaa
    26761 ccacatcgaa atcgttgggg acatgccaat ctacgtagcg gaagattcaa gtgatatgtg
    26821 ggcaaatcca catctcttca aaacagatgt caatggtaag gctacttgta tcgcaggatg
    26881 cccaccagat gagttttctg taactggtca gctttggggt aatccaatct atgactggga
    26941 agcaatggac aaagacggct acaaatggtg gattgaacgc ttgcgtgaaa gcttcaaaat
    27001 ctacgatatc gttcgtatcg accacttccg tggcttcgaa tcttactggg aaatccctgc
    27061 tggttccgat acagcagcac ctggtgagtg ggtgaaaggt ccaggctaca agctttttgc
    27121 agccgttaag gaagaacttg gtgagctaaa catcatcgca gaagaccttg gcttcatgac
    27181 agatgaagtg atcgaattgc gtgaacgtac tggcttccca ggaatgaaga ttcttcaatt
    27241 tgccttcaac ccagaagacg aaagcattga tagcccacac ttggcacctg ctaactcagt
    27301 tatgtacaca ggaacacacg ataacaatac ggttcttggt tggtaccgta atgagattga
    27361 tgatgcgact cgtgagtaca tggctcgtta cacgaaccgt aaagaatacg aaacagtggt
    27421 acacgctatg cttcgtacag tattttcatc agttagcttt atggcaattg caactatgca
    27481 agatttacta gaattggatg aggcagctcg tatgaacttc ccatctaccc ttggtggaaa
    27541 ctggtcttgg cgtatgactg aagatcaatt gacaccagct gtcgaggaag gtttgcttga
    27601 cttgacaaca atttatcgcc gaattaatga aaatttggta gatttaaaga aataagacaa
    27661 taatcaggag acaactaaac atgttatcac tacaagaatt tgtacaaaat cgttacaata
    27721 aaaccattgc agaatgtagc aatgaagagc tttaccttgc tcttcttaac tacagcaagc
    27781 ttgcaagcag ccaaaaacca gtcaacactg gtaagaaaaa agtttactac atctcagctg
    27841 agttcttgat tggtaaactc ttgtcaaaca acttgattaa ccttggtctt tacgacgatg
    27901 ttaaaaaaga acttgcagct gcaggtaaag acttgatcga agttgaagaa gttgaattgg
    27961 aaccatctct tggtaatggt ggtttgggac gtttggctgc ctgctttatc gactcaattg
    28021 ctactcttgg tttgaatggt gacggtgttg gtcttaacta ccactttggt cttttccaac
    28081 aagttcttaa aaacaaccaa caagaaacaa ttccaaatgc atggttgaca gagcaaaact
    28141 ggttggttcg ctcaagccgt agctaccaag taccatttgc agactttact ttgacatcaa
    28201 ctctttacga tattgatgtt actggttatg aaacagcgac taaaaaccgc ttgcgtttgt
    28261 ttgacttgga ttcagttgat tcttctatta ttaaagatgg tatcaacttt gacaagacag
    28321 atatcgctcg caacttgact ctcttccttt acccagatga tagtgaccgt caaggtgaat
    28381 tgctccgtat cttccaacaa tacttcatgg tttcaaacgg tgcgcaattg atcatcgacg
    28441 aagcaatcga aaaaggaagc aacttgcatg accttgctga ctacgcagtt gtccaaatca
    28501 acgatactca cccatcaatg gtgattcctg aattgattcg tcttttaact gcacgtggta
    28561 tcgagcttga cgaagcaatc tcaattgttc gtagcatgac tgcctacact aaccacacaa
    28621 tccttgctga agcgcttgaa aaatggcctc ttgaattctt gcaagaagtg gttcctcact
    28681 tggtaccaat catcgaagaa ttggaccgtc gtgtgaaggc agagtacaaa gatccagctg
    28741 ttcaaatcat cgatgagagc ggacgtgttc acatggctca catggatatc cactacggat
    28801 acagtgttaa cggggttgca gcactccata ctgaaatctt gaaaaattct gagttgaaag
    28861 ccttctacga cctttaccca gaaaagttca acaacaaaac aaacggtatc actttccgtc
    28921 gttggcttat gcatgctaac ccaagattgt ctcactactt agatgagatt cttggagatg
    28981 gttggcacca tgaagcagat gagcttgaaa aacttttgtc ttatgaagac aaagcagctg
    29041 tcaaagaaaa attggaaagc atcaaggctc acaacaaacg taaattggct cgtcacttga
    29101 aagaacacca aggtgtggaa atcaattcaa attctatctt tgatatccaa atcaaacgtc
    29161 ttcatgagta caaacgccaa caaatgaacg ctttgtacgt gatccacaaa taccttgaca
    29221 tcaaagctgg taacatccct gctcgtccaa tcacaatctt ctttggtggt aaagcagctc
    29281 cagcctacac aatcgctcaa gacattatcc atttaatcct ttgcatgtca gaagttattg
    29341 ctaacgatcc agcagtagct ccacacttgc aagtagttat ggttgaaaac tacaacgtta
    29401 ctgcagcaag tttccttatc ccagcatgtg atatctcaga acaaatctca cttgcttcta
    29461 aagaagcttc aggtactggt aacatgaaat tcatgttgaa cggagctttg acacttggta
    29521 ctatggacgg tgctaacgtg gaaatcgctg agttggttgg agaagaaaac atctacatct
    29581 tcggtgaaga ttcagaaact gttatcgacc tttacgcaaa agcagcttac aaatcaagcg
    29641 aattctacgc tcgtgaagct atcaaaccat tggttgactt catcgttagt gatgcagttc
    29701 ttgcagctgg aaacaaagag cgcttggaac gtctttacaa tgaattgatc aacaaagact
    29761 ggttcatgac tcttcttgat ttggaagact acatcaaagt caaagagcaa atgcttgctg
    29821 actacgaaga ccgtgacgca tggttggata aagtcatcgt taacatttct aaagcaggat
    29881 tcttctcatc tgaccgtaca atcgctcagt ataacgaaga catctggcac ttgaactaat
    29941 actcttcgaa aatctcttca aaccacgtca gctttatctg caacctcaaa gcggtgcttt
    30001 gagcaacctg cggctagctt cctagtttgc tctttgattt tcattgagta taagatacaa
    30061 atttatacta atacatcttg taaaaaagcg agtttcgatt gaaattcgct tttttaaatg
    30121 ctgtggattt gggtcaatct tgtctaaaaa tagggaaatc ctagatacag tgaaggcttt
    30181 aaatgctggt ttttactgtc ttcagcctta tattttttcg tagttggtta cctcatatct
    30241 cttgtattcg cttacataaa gtattataat ataattgtag gaaagaaggt gtttttatga
    30301 tatacacact taaattggtg ttgtttatta cctttcttgt aataagcttg ttacctgata
    30361 agatttttgg aaaaaataaa aaaatttgga aaatagtttt tgcaatattg acggcagtgg
    30421 cagcattgtc atttatgtac taagttattt taagaatgta gggaaataaa ccctacattc
    30481 tttttagttt tttctgtttt ctaaattcta tttatccaag cgcttcaaca tttcttgctt
    30541 cttcgcttca agttctgcac gcttttcttc gatttcggca tgttttttct cgagttcaga
    30601 acaacttgca tcattgctaa attcttttcg ccatcaggag atagggtgag tcgacatgtc
    30661 tattactcac ccaaagcagt cctacaaagc aggaattttc tgttactttt ttggaaatag
    30721 taacgtttat acagctttga cacttcgtat caaagcgcca aacacactcc gagggattta
    30781 cagaaagcag aaaaggaatg atctggtata agatcattcc ttttctctct ttttctttaa
    30841 gtaattatat acaatgtacg acgaagtcgt cattgcaatg ctgatccacc acctaaaggg
    30901 aactttaaac aacattgata agataaagaa tataaacaac gaaaatacgt tatacccaat
    30961 taattttatt gtatatctca tgattaaaag ttaatccttc cgttgttagg aatggcatca
    31021 tttttatccc ataattgtgc taaataagtc cccggtgata ataaattcat agcgaattct
    31081 aaagcaacat catttacaaa ccaactacct agatatctag aaattgctga acgaatagca
    31141 ctttttgctg catgttttcc ttttacttta attagatttg caaggcctgc agtagttcct
    31201 cctaaggcta aagctattgc agtatctaat agagcaccca tttgattaac tgtaatacct
    31261 tgccaagctg ctctaaatgg agagtatgta ggtgggattg tataatcgcc ttgtaattgt
    31321 cggttaatta cttctttgat ccattgttgt gagacgtctg gatgaaaaga ttggatttcg
    31381 tttgcaagtg tattgatttg ttcttctgtt agagaagtga caggttgaag ttccatattt
    31441 gtttcaattt gcgatacttg ttcagaagcg tatacagctg aaacacttgg aatcgctgat
    31501 acaattaaca caattgacgt caaaaaaccg aaataaattt cattaatttg ttcatgagct
    31561 tttctccttt ttatttgtat ctgcttacat tttattatat actgttatta tagtcaagaa
    31621 aaatatgcta ttatgttaaa aaaatatttt tcaaaatata aatggacgga tttattttgg
    31681 attttatttg ttattttgac ctgcctctat attggtaacc atgatttgtt tactctcaat
    31741 catcaagaat tctcttttcg tggtagcttt tggggtttgg tactgacctt atatcactta
    31801 ttgttcattg ataagtttgt aatttcgaat cgaaaataaa gattagagct atgcttgact
    31861 gtgtactttt aggattgatt ttggaggaag attttgtctc tattatttat tattttaaat
    31921 ttatttattt tgtataagat ctattctttg aggcgggaaa aatcgaaata cttgatttat
    31981 acggcctata tcatatttgg ggtaaatgta gtatatggta ttcaatggtt attaaaagaa
    32041 ctgatttcaa ctatttcccc ttaatgcgta tggaaactat aacaaaacgc ataagattaa
    32101 ggtttgtgta cctgttctta tacgtttttg tcatattgaa gattttcggt aagttttcta
    32161 cttttgcgaa gtctagttta tactcaatga aaatcaaaga gtaaactagc cgtaggttgc
    32221 tcaaagtaca gctttgaggt tgcagataaa actgacgaag tcagctcaaa acatggtttt
    32281 gaggttgtag atgaaactga cgaagtcagc tcaaaacatg gttttgaggt tgtagatgaa
    32341 actgacgaag tcagctcaaa acatggtttt gaggttgtag atgaaactga cgaagtcagt
    32401 aaccatacgt acggcaaggc gacgttgacg tggtttgaag agtattagaa tgctttccca
    32461 accagaatct ctgcttcgat ggtaatctct gtcagttggc tccagtcaat cttgctctgg
    32521 tcaacgtgaa agaggagagg agtcatactg agtagggctt ggagttgttc tgctgtgata
    32581 gtcttagtca gagaggcagt ttgactagat aggatggtaa agtgttcctg gaaatgctcc
    32641 ttgatatctt ggttagaata ctccttgttt gtcagctggt cctgtactct ttgacggatt
    32701 tctttgaggt gattttcagt tgggataacc tttatcaaga taccgtcttt ggataaaacg
    32761 cgacgaaatt ctccatagtt ggcaggtgag aagatatcaa gcagaatatc catgttagcg
    32821 tcttttatag gaaggcgtgc caagtcgcca acgaaccaat tgactgccca gttgggttca
    32881 cttttagcag cgatttggac tgaatctttg gagatgtcaa aggcatagaa agttttttca
    32941 gagtgacttt cttgtagttt gcgagaatag aatccttcac cacaaccgat atccaaaatt
    33001 gttgtggtag tttttgagct tgcaagcaag tcagatacag catctaagat agcttggtaa
    33061 aagccggctt ctaggatttg ttgacggttt tgaaaatttt ccttgtcata gttagcagat
    33121 tgcttgattt gaggtgctag attgacatag ccaaatttcg ccaagtcaaa agaatgacgg
    33181 ttgcagcact tgaaattagt ctctaacaga gtcagatttt cttgacagat aggacaggca
    33241 aaggcagtcg cagaagcaaa acgctgaagt ttgggcttga gatttgtatt catagtttaa
    33301 gtgtatcaaa agaggcaaat gaaagcaact ttaggaataa gtagatggga gattcagtag
    33361 aaataaaact aattctccaa tttatagaat gaaattgctt ttatatctaa attgctatat
    33421 aataatgata aggaggaaat aagtatgtta aaagaagtat taaccgttgc aaaagttgcg
    33481 aaaaaatctt cattattttt gggtggtgtc gcatttggta cccttggttt gaaaatctta
    33541 gcaagtaagg aagctaaaaa aggttattct aaagctttgg ctaaggctta caagttgaaa
    33601 gacgagctag atgcatctgt ttctgttgtg aagcaacatg gagacgatgt cttgcaagat
    33661 gccaaatatt tgtacgagca agagaaaaaa gaagagcaat tagatagcct tataggtgaa
    33721 taatatgtct tttaaagtgc tacatagagg ataccaacat atccgactat catcttcttt
    33781 ttcacttacc ttggatattc aagactatct tcgttccttg gcgagagatg aaaaggggat
    33841 tgagtctatc cagttttaca tggatcaaca gcactttact ctacgcataa aagaaggctt
    33901 ttctgtatta gataatgcag aagccttttt aaaaagaatt gataaaggga aagtttctga
    33961 gttgatgact cttcccattc gtagagaaga gagtgcttat tctattgttt caggtgcagc
    34021 ggttaagcgt gtactttttc gtagttttgt gccgtatcct attcgctata tatggacttg
    34081 ttatcaggct ttgggttata ttagagaagc ctatcaaaca ctagcgcgta aggaactaac
    34141 gatggaagtc ttggactgtt cggctatttt attgtctttg tttatgaacc aatccaagac
    34201 agctagcaat atcatgttta tgcttgattt ggggaatcat ttagatcagt ggtccttgaa
    34261 aaaaactgca acagatttag aacagagtct tcttgcaaaa gagagcgatg tattcctagt
    34321 acagggcgat acggttgtta gtatcaagag ttccgatgtt caaataggag atgtcttgat
    34381 cttatctcaa ggaaatgaaa ttctgtttga tggacaagta gtttcaggtt taggtatggt
    34441 caacgaaagt tccttgacag gagagagttt tccagttgaa aaaagagagt ctgatttagt
    34501 ttgtgcaaat acagtattag aaactggaga gttacgcatt cgtgtaacag ataatcagat
    34561 gaacagccgt attttacagc tgattgagtt gatgaagaaa tctgaagaaa acaagaaaac
    34621 gaaacaacgc tatttcatca agatggcgga taaagtcgtc aaatataatt tcttgggggc
    34681 tgggctgact tacctattga caggttcttt ttctaaggct atttctttcc tattggtcga
    34741 tttctcctgc gctttgaaaa tctctactcc tgtagcttat ttgacagtta tcaaggaagg
    34801 gttgaaccgt gaaatggtga ttaaggatgg agatgttctg gagaaatatc tggaagttga
    34861 tactttcttg tttgataaga caggaacaat cacaactagt tatcctatag ttgaaaaggt
    34921 gttacctttt ggagactata gtgaggaaga tattctcaga atcagtgcct gtcttgagga
    34981 acacatttat catcctattg ctaatgccat cgtcaagcaa gctgagatag agggaattga
    35041 acatgaggaa atgcatggga aactccaata tatcgcaagc aaggggatca aatctcatat
    35101 agatggccaa ccagttctta ttgggaatta tgtcttgatg caggatgagc agattcatat
    35161 cagttcagaa caaaatgctt taattgaaga gtacaagagt cactacaatc tcttattctt
    35221 ggcttatcaa aatgaattga ttggaatgtt ctgcattcat actcctttga gaaaagaagc
    35281 aaaaacagcc ttggataaac ttaaggcaca ggggaaaaaa ttgattctgg caacaggaga
    35341 caccttgatt aggacagagg aattagtcaa agatttgccc tttgatcagg tctatacaga
    35401 cttgaaacct gatgggaaat ttgagttagt agagaaactg cagaaagcag gtcacactat
    35461 tttgatggtt ggagatggat tgaatgactc agcggcttta actctatcag atatcggtgt
    35521 ggtgatgaat gagagtgcag atatttctaa gcagatgagt gatatcttat tgttagataa
    35581 tcgtttggat ttcttccaag agttggattc gttatcatca tctttgcaaa cactcatcaa
    35641 gaaaaatatt caagataccg ttgtcgtaaa tagtagtttg attggcttcg gcttatttaa
    35701 ttggctcagt ccttcaaatc tctctatctt acataatcta acaaccttgc gcattgtcct
    35761 gcgtagcctg tctattaaaa atagatagat gagagttatt aacagcaaaa aggagttacc
    35821 tttctcgagg ttaactcctt tgtttataga taaatgttga atagtttagt aagtcaatac
    35881 aaagtatttt ttcttcccac gacggataac agtcagttca ttttctaact tatcagcgtc
    35941 actcaagaca tagtcaaggt cttggatgcg gtcgccgttt acgtagatgg ctccgttttg
    36001 gacgtcttca cgggcttggc gttttgagtt aactatacca gatgagacga gcagttccac
    36061 gatattgttg ttttcgtctg cctgtacttg gtagtttggc acaccacgaa gtccttgttt
    36121 gagctctttg acagaaaggt ttttgatgtt tcctgcaaag agttgctcag tgatgttaag
    36181 tgcttctttg taggcttctt ctccgtgaac aagtgtaaca acttcacgag ccaagacttt
    36241 ttgagccaag cgttcgtgtg gcgctgcttc aaattgttta cgaatatctt caatctcatc
    36301 aagtgacaag aaagtaaaga ttttcaagaa gcgaacagcg tcagcgtcca tcacgttcat
    36361 ccagaattgg tacatttcgt atggagaagt cttttcggga ttgagccaga cggcatttcc
    36421 ttctgattta ccaaattttt taccagttgc atctgtgatt agtggaacag tgataacgtg
    36481 accagtcttg tccgccttac gacgaagcaa ttcggtacca gctgtcatat ttccccactg
    36541 gtcagaacca ccgatttgaa gagtgacatt atggtcttgg ttaaggacga agaagtcgta
    36601 cccttgcatg atttggtaag cgaactcagt gtaagaaatt cctgtttcga tccgtttttt
    36661 aacagattcc ttactcatca tgtagttgac cgtgaagtat tttccaatat cacggaggaa
    36721 gtcaatgaag ctgatgctgc caaaccagtc gtagttgttg accatgacag ccttgttttc
    36781 gccattttca aagtcaagaa aacgagaaag ttgtccttgg atagacttga cccagccatc
    36841 tactgtgtct tttgtttgga gactacgttc agcatctttg aaggacggat ctccgatgag
    36901 acctgtagca ccgccaacga gcgcataagg tttgtgacct gctagttgca agcgacgact
    36961 tgtcaagatt gcgacaaggt ggcctaggtg aaggctgtca gcagttggat cgtagccagt
    37021 ataataagaa acttgacctt cttctagggc tttacgcaaa gcttcttcat cagtcgtttg
    37081 aaatatcaaa ccacgctctt ttagctcatc aaaaatgtgc atgtgtcttt tctccttttt
    37141 aaaattattg tttctaccta ttgtatcaca aacttgggca atagcctagc agaataggga
    37201 agaaagtggc tattttattg aaaatttccc ttttgtggta taatagataa agtgaggaaa
    37261 tccatgcaaa atcaattaaa tgaattaaaa cgaaaaatgc tggaattttt ccagcaaaaa
    37321 caaaaaaata aaaaatcagc tagacctggc aagaaaggtt caagtaccaa aaaatctaaa
    37381 accttagata agtcagccat tttcccagct attttactga gtataaaagc cttatttaac
    37441 ttactctttg tactcggttt tctaggagga atgttgggag ctgggattgc tttggggtac
    37501 ggagtggcct tatttgacaa ggttcgggtg cctcagacag aagaattggt gaatcaggtc
    37561 aaggacatct cttctatttc agagattacc tattcggacg ggacggtgat tgcttccata
    37621 gagagtgatt tgttgcgcac ttctatctca tctgagcaaa tttcggaaaa tctgaagaag
    37681 gctatcattg cgacagaaga tgaacacttt aaagaacata agggtgtagt acccaaggcg
    37741 gtgattcgtg cgaccttggg gaaatttgta ggtttgggtt cctctagtgg gggttcaacc
    37801 ttgacccagc aactaattaa acagcaggtg gttggggatg cgccgacctt ggctcgtaag
    37861 gcggcagaga ttgtggatgc tcttgccttg gaacgcgcca tgactaaaga tgagatttta
    37921 acgacctatc tcaatgtggc tccctttggc cgaaataata agggacagaa tattgcaggg
    37981 gctcggcaag cagctgaggg aattttcggt gtagatgcca gtcagttgac tgttcctcaa
    38041 gcagcatttt tagcaggact tccacagagt cctattactt actctcctta tgaaaatact
    38101 ggggagttga agagtgatga agacctagaa attggcttaa gacgggctaa ggcagttctt
    38161 tacagtatgt atcgtacagg tgcattaagc aaagacgagt attctcagta caaggattat
    38221 gaccttaaac aggacttttt accatcgggc acggtcacag gaatttcacg agactattta
    38281 tactttacaa ctttggcaga agctcaagaa cgtatgtatg actatctagc tcagagagac
    38341 aatgtctccg ctaaggagtt gaaaaatgag gcaactcaga agttttatcg agatttggca
    38401 gccaaggaaa ttgaaaatgg tggttataag attactacta ccatagatca gaaaattcat
    38461 tctgccatgc aaagtgcggt tgctgattat ggctatcttt tagacgatgg aacaggtcgt
    38521 gtagaagtag ggaatgtctt gatggacaac caaacaggtg ctattctagg ctttgtaggt
    38581 ggtcgtaatt atcaagaaaa tcaaaataat catgcctttg ataccaaacg ttcgccagct
    38641 tctactacca agcccttgct ggcctacggt attgctattg accagggctt gatgggaagt
    38701 gaaacgattc tatctaacta tccaacaaac tttgctaatg gcaatccgat tatgtatgct
    38761 aatagcaagg gaacaggaat gatgaccttg ggagaagctc tgaactattc atggaatatc
    38821 cctgcttact ggacctatcg tatgctccgt gaaaagggtg ttgatgtcaa gggttatatg
    38881 gaaaagatgg gttacgagat tcctgagtac ggtattgaga gcttgccaat gggtggtggt
    38941 attgaagtca cagttgccca gcataccaat ggctatcaga ccttagctaa taatggagtt
    39001 tatcatcaga agcatgtgat ttcaaagatt gaagcagcag atggtagagt ggtgtatgag
    39061 tatcaggata aaccagttca agtctattca aaagctactg cgacgattat gcagggattg
    39121 ctacgagaag ttctatcctc tcgtgtgaca acaaccttca agtctaacct gacttcttta
    39181 aatcctactc tggctaatgc agattggatt gggaagactg gtacaaccaa ccaagacgaa
    39241 aatatgtggc tcatgctttc gacacctaga ttaaccctag gtggctggat tgggcatgat
    39301 gataatcatt cattgtcacg tagagcaggt tattctaata actctaatta catggctcat
    39361 ctagtaaatg cgattcagca agcttcccca agcatttggg ggaacgagca ctttgcttta
    39421 gatcctagtg tagtgaaatc ggaagtcttg aaatcaacag gtcaaaaacc agggaaggtt
    39481 tctgttgaag gaaaagaagt agaggtcaca ggttcgactg ttaccagcta ttgggctaat
    39541 aagtcaggag cgccagcgac aagttatcgc tttgctattg gtggaagtga tgcggattat
    39601 cagaatgctt ggtctagtat tgtggggagt ctaccaactc catccagctc cagcagttca
    39661 agtagtagtt ctagcgatag cagtaactca agtactacac gaccttcttc aagggcgaga
    39721 cgataattct ctaaatgaag tggccaatca atggattgcc acttttttcc tttcgtgtta
    39781 caataagggt atgaatcagt atcagaaaaa gattgttaac ggaaaaattt attcgctcct
    39841 atccggctta atatggggaa tctgtggaat tttaggagag tacttcttta ctcattatca
    39901 ggtgtcttcg ggctggatta cctctatgcg tttgacactg gcagggagtc ttgtactcat
    39961 ttggtctgca atacaattaa aatcgcaagt gctagatatt tggcgagaca agaaaaatta
    40021 cctgcccttt ttagcctatg ctattttggg gattttttca gttcagtatt ttttctatct
    40081 ctgtgtagaa tactcaaatg ctacgacagc aactatttta cagtttatta gccctgtctt
    40141 tatcctcttt tataatcgct tggtttatca aaaacgagcg tcaaaaagcg ctgttttcta
    40201 tgttttggtt gccatgctgg gtgtttgctt gatggcgaca aagggagatc tctctcagtt
    40261 atccatgacg ccgctagctc ttataacagg tttgctgagt gccatgggtg ttatgtttaa
    40321 tgttatcttg ccccaacctt ttgctaagcg ttatggtttt gttcctacgg ttgggtgggg
    40381 gatgattttg gcaggtttgt ttagcaatgt cctctcgccg gtttatcagc tttcctttac
    40441 tcttgatatt tggagtatct tgatttgcct cattatcgct ttctttggaa cggcttttgc
    40501 ttttttcatt tccatgaagg ctgtgtcctt ggtttctcct ttggtggttt ccgttatcag
    40561 tgccagtgaa cctctctctt ctgctctctt gagtgttttg ttcttaggat tagtagtgga
    40621 ttggtccctc cttctagcta tagccttgat tattttaccc atgatatttt tgtctataga
    40681 agaagcgaaa gaaagtagat aaaaagtctt ttcttaattc taaaagtgtg ctatactaga
    40741 atagtcaata aaacacgggg agatagttgt gaagagtgtt tttaggttgt atcggtaggg
    40801 gcttgctttt accgacagca cgttttatct cacaacccta aaaaatcata cctaaaaaca
    40861 gacaaaaagg tttcaaattt gaggcctttt ttggtagaat aggtatcatt ataacgaacc
    40921 aggaggcacc tatgactgct acaaaaatga acgctcaaga aattatccaa tttatcgcca
    40981 atgctgaaaa gaaaaccagt gtcaaagtaa cctttgaggg gcaactcgca actgctgtgc
    41041 ctagctctgt tgtcaaacta ggaaatgtcc tattcggaga ctggaaggac gtggctccgc
    41101 ttcttgaagg tttggtagaa aatcaagatt atgttgtcga gcaagatgct cgtaattctg
    41161 cagttccttt gctagataag cgtgctatca acgctcgtat cgagccaggt gctattatcc
    41221 gtgaccaggt ggaaattggt gacaatgctg ttatcatgat gggagctgtt atcaatatcg
    41281 gtgctgaaat cggtgctgga accatgattg acatgggtgc catccttggt ggccgtgcta
    41341 tcgttggaaa aaatagccac gttggtgcag gtgcagtttt ggcaggtgtg attgagccag
    41401 ctagtgctga accagtccgt gtcggagaca atgttcttat cggtgctaat gcagtggtta
    41461 tcgaaggagt ccaaatcggt agtggttcag ttgtcgcagc aggagctatt gttacccaag
    41521 atgtcccaga aaacgtggta gtagcaggtg ttccagctcg tattatcaaa gaaattgatg
    41581 cccaaactca acaaaaaaca gcgctagagg atgcgcttcg taccttgtaa ttgtaaaagt
    41641 aaaaaagagg cggaaccctt tttccagcct ctttctgcta tatcggagga cagatagatg
    41701 ttagatttga ttcagactag acgagattta caccagatac cagagattgg cttggaggag
    41761 ttcaagactc aggcttattt gctggatgtg attgagaaat tgactacggg caaggatttt
    41821 gttcaaattc gtacttggcg gacagggatt ttggtctacc tgcagggaag tcagccggag
    41881 cgaaccattg gttggcggac agatattgat ggcctgccta tcgtcgaaca aacaggtcta
    41941 ccttttgctt ctcaacacca aggtcgcatg catgcctgtg gtcatgattt tcatatgacc
    42001 attgccttag gctgtcttga gcgcgccctt gaggagcaac ccaagaataa tctgctcttt
    42061 ctatttcagc ctgctgaaga aaatgaagct ggtggtatgc tcatgtatga ggacggtgct
    42121 tttggagatt ggttgccaaa ccaattctat ggtctccatg ttcgtccaga tttgaaagtc
    42181 ggccagattg cgactaatac tcatacactc tttgcaggaa cttgcgaggt gaagatccgt
    42241 ttcaaaggca aaggtggcca cgcagctttt cctcatgaag ccaatgacgc cttggtggcg
    42301 gctagttact ttgtgaccca agtgcagtca gttgttagcc gcaatgtcaa cccaatcgag
    42361 ggagcagtgg tgaccttcgg cgtttttcaa gctggaacca ccaacaatgt catcacagac
    42421 acagcttttt tacatggaac tattcgtgcc ttgacacagg acatgagtct cttggtgcaa
    42481 aagagggtaa aaacagttgc agaaggggtt gcagctgcct ttgatatgga agtcgaagtg
    42541 gaactcaaac aaggtggata cctacctgtt gagaacaatc cagccttggc gcgtgaactg
    42601 atggacttct ttgacgaaaa agacggaatc gagttgattg atatcgaacc tgctatgaca
    42661 ggcgaggact ttggttatct cctttcaaag gttgatggcg tgatgttttg gctaggtatc
    42721 gatagtccct acgctcttca tcaccctcaa atgagtccta aggaagaagt cttagctatt
    42781 ggggtggctg cggtgtctag tttcctgaaa aagaaggcag cagaatagag ggcttgtata
    42841 tgaaatcgga attacgcaag caagtcttgc atgaaatgaa ggctttatct caagaacaaa
    42901 aacaggctat agaccaagct ttaaccgagc gaattttaca acaccccttt tatcaagaag
    42961 ccaaggtcat cgcaacctac ctctcttttt ctcatgagtt tcaaacgcgg gaactgattg
    43021 agcaggcgct gaaggacggc aagaaggttt taatacccaa aacttatccc aaggggcgca
    43081 tggactttgt agtctatgat ccgcagcagt tggtaaaaac tgcctttgcc ttactggagc
    43141 cacagggaga tttggaagtg gtggatgtat ctcagattga tttgattcat gttcctggcc
    43201 tggcttttac gacggatgga tatcggattg gatatggtgg aggttattat gaccgctatc
    43261 tggaacattt ttctggtcgt actttgagta cggttcatcc ttgtcaaatt caggacttta
    43321 tacctgaaaa ccatgatatt cctgttcagg aggtattaat tgatgaagga aatctttgat
    43381 agacgttacc ctgtgacgag tttcttcctc ttagtgacgg ccttggtatt tttactaatg
    43441 ttggtcactg caggcggaaa ctttgacagg gcagatacat tatttcgatt tggagccatg
    43501 tatgggccag ctattcgcct ctttcccgag caggtttggc gtctcttgtc tgccattttt
    43561 gttcatattg ggtgggaaca tttcattgtt aatatgcttt cactttatta tcttggaagg
    43621 caggtagagg agattttcgg ctctaagcag ttcttttttc tctatctctt atcaggaatg
    43681 atgggcaatc tctttgtttt tgtatttagt cctaaatcct tagcagcagg cgcctctacc
    43741 tctctttatg ggctatttgc cgcgattatt gttcttcgct atgcaactcg caatccttat
    43801 atccaacagc tagggcaatc ctatctgaca ctttttgtgg ttaacattat tggaagtgtt
    43861 ctgattccag gaatcagcct agcaggccat atcggtggtg cagttggtgg cgcatttcta
    43921 gcagttatct ttccagttag aggagaaaaa cggatgtata acaccagcca gagattagga
    43981 gcggtagtct tgttcgtagg actcgccatt ttgcttttct acaagggaat gggaatgtga
    44041 cgactaatac tcaatgaaaa tcaaagagca aactaggaag ctagccgcag gttgctcaaa
    44101 gcactgcttt gaggttgtag atagaactga cgaagtcagc tcaaaacatg gttttgaggt
    44161 tgtagatgaa actgacgaag tcagtaacca tatatacggt aaggcgacgc tgacgtggtt
    44221 tgaatttgat tttcgaagag tataatatgt aaacttgaat aagaaaaaag ctacttaaaa
    44281 aatgagtagc ttttaatgtg ttttggaacc attcgaaaca acacagctct aaaatagtta
    44341 ttagcgttgt ggaggttctg caatgcctcc cccagtgttt ccaagataat tccaattttc
    44401 gtcaaacaca tctccattgc tctcattgtc gtaagtataa cttacatgtc catcagcacc
    44461 aatattctta tattttttat agtagccatt atttactccg ctgttggaat tgctagatga
    44521 atattgttct gatgatccac catttgttga actatctcca gaaccagaat aactttgact
    44581 tccataatta ttcgaatatc cattagtttg ttcagatgaa ctataatcta catttgaatt
    44641 ggaagatcca ttataagact cattagaagc accactagaa gaattacttt gactagaaga
    44701 ttcctttgct ttttcagcag ctttttcttc ttctttcttc aaaagttcga tttgtttttg
    44761 atatttatca acaagatcat ttagagattt aagagtttct tccaaattct cttgtttaaa
    44821 agtttcatca acttttttga taaaatcaat ttgttttgta atttctttca catttgtttc
    44881 aagagttgct ttatctttaa acttctcatc agaatcttta acatcataag ccaaaccttt
    44941 ttgcaaatga aaatctacaa ttgctttaga tgattctttg actttgttat taagatagtc
    45001 tttacctgca tcggttttaa gtgaagtttc agatagttct tttaatttag aaatagattc
    45061 atctgaagat gcatcaaatg attcaaatag tttatcaact tgttctttgt ctgatttgct
    45121 atctttttct aattgtacaa tttttgcttg ttgttctgct tgttgttggt tatatgaata
    45181 ccatccaaac cctaatacca atacaacacc aactgcaact gatgaaatga ttactttttt
    45241 attgttttcg ataaattcta caaatttgtt ctccataatc ttttactttg atagtgtccg
    45301 caattacttt aaaattaaaa ttacacctat ctttctccct tattatattt ttattaatag
    45361 cttccacaaa attaaacaac ttatgttcgg ctcggttgat ttaatttaac catgactact
    45421 ccaacagtta agtcaaattt aaaattattt attattttgg aaccattaga aacaacatag
    45481 caaagttaaa ataaggcttt gtccgtacac aacttgaaaa agtgcgcacc gattcggtgc
    45541 ttttttgttt tactatacta atttattcta ctcttatttt aatgaaaaaa caaatacaag
    45601 tatagcgttt tcattagttt ttattaaata ggtagattca agtagagaat ttacttaatt
    45661 tatgtgtggc taatctttat ataaatgatt ttgttattcc ttctcagtca attcttttcc
    45721 aagttggatg aggtaattct tcaaatcatc tttgacttgt ggatgtttga gggcgtagtc
    45781 gatggatgtt ttcatgaagc caaacttgtc tccgacatcg taacgagccc ctttgaactc
    45841 acgagcaaat acacgttgtg ttttattgag ggtgtcgatt gcatctgtca gctgaatttc
    45901 atttcctgca cctggagctt gcttttcgag aatctcaaaa atttcaggcg tgaggaggta
    45961 gcgtccgata atagcaaggt cgctaggagc gtcctctgga gctggttttt caacaaaggt
    46021 ttcaacactg taaagaccat cttttccttc gccttgcgga gcaataaccc cgtaagcaga
    46081 tacttcgtca tgagggactg gcatgacagc gatagtagac gcgtgggtac gctcgtagtc
    46141 atccatgagt tgtttggtaa gtggaacagc cttttcgtct gtgatatcca tcaagtcatc
    46201 accaagcata acgacaaaag gttcatttcc gacgaaagcc ttggcttgca aaacagcatc
    46261 tccgagaccg cgtggatgag tttggcggat aaaatgcaga cgcatgccag ttgtttcatc
    46321 aactagcttc aaaagatctg ttttcccttt ttctttgagg ttatattcca attcgaagtt
    46381 tgaatcaaag tggtcctcaa tagaacgttt tgatttacca gtgacaacta gaatatcttc
    46441 aatacctgat ttgagagctt cttccacgat aaactggata gttggtttgt ctacgattgg
    46501 caacatttct ttggcaaggg ccttggttgc tggtaaaaat cgagttccta gtccagcagc
    46561 agggatgact gcctttctaa cttttgatgt cataaaaatc ctttctatag agggttaaga
    46621 ccactcattt tctgctttaa attcattgtt catgatgtca taaatggcat ctttgatatt
    46681 ggttccgtga taaataactt ggtaaatagc ctgtgtaatg ggcatataga ctccaagttc
    46741 ttgggctagt tcataggctg ctcgagtcgt tgaaattcct tcgattacca tgcccatatt
    46801 agcttctata tcagctaggg attctcctcg tccgagagca tctccagctc tccagttacg
    46861 agagtggatg gaagttcccg ttacgatcaa atctcccaca ccagataagc cgctataggt
    46921 caatggactg gccccgagtg ctacccctag gcgggtgatt tctgctaaac ctcgagcgat
    46981 gatggctgcc ttagcattat caccaaatcc aagaccatgt aaagctccag caccgacagc
    47041 aataatattt ttaagagcac cagcagtttc aaccccgata acatccgtat tggtataaag
    47101 tcggaagtag tgattactaa atagcttctg aacgtattga gctgtttgta aatctttaga
    47161 agcagcagtt attaaagtta ggtcacgcac aatggtctct tctgcatgac taggccctga
    47221 aacaacgacg atatcactac ggagatgttc aggaatttct tcttcaagaa tggttgataa
    47281 tcgtttatgg ctatcaggtt ctaatccctt tgatgcgtgc atgatgataa ccttatggtc
    47341 caaggtttgt gcaacttgct gggcaacaag tcgtgtcact tttgttggga caacaaacaa
    47401 aatcgcatcc acatctttca atgtttctgc taagtcggtg taggcaatga tattttcgtc
    47461 tagaacgaca tctttaaagt agtgcttatt agtatggtgt gtattaattt cattgatttg
    47521 ctcgggaaga tttccccaaa tacgtacctc gtgtccattg tcatttaaga cttgtgaaag
    47581 ggcggttccc caagaaccag gccccaagac ggcgacggtt tgtttttcca tgatttcctc
    47641 cttgatagag ttctttctct tattctatca tattctaggg gattttgcac ttgcattact
    47701 ggggtatggt ggaaaaatac acaaaaaccg agacgaaggg ataaactctt agtctttagt
    47761 taaagtgaga agaaatctga tagatagttt gattcagtat atgcttataa tagaggtaaa
    47821 caactcagga ggttcttgta ggttgcgaga gtttggcgaa aaaattaaaa gattacgttt
    47881 ggctaaaaaa atcagtcgtt cagaattttg tggtgatgag tctgaattaa gtatccgtca
    47941 attaattaga attgaaaatg gagaatccag accaacacta acaaagttaa aatatatcgc
    48001 tgaacgtttg ggggttgagg attacaagtt gatgccaagt tatatagagt tggataagga
    48061 atacctagaa ttgaagtatt ttttgatgag gactcctaca tacgaagatg aaactatcgc
    48121 ccaaaagaaa gagagtgttt tgataagatt tttgaagagt attatgatag gctacctgag
    48181 gaagaaagat ttatcatccc aaattattca tatctggcac taacgaacta cacagttcaa
    48241 aaattaccag aaaagctagt tgaaatactg tccttctggt gattttgctt aatttctgat
    48301 gttcgagaca taattgagga gatttgtctt gattttttcc taaaaaaggg cagacttctc
    48361 ccttggtttg atgctcgatt tttaaaataa ggtgacttat tctgttaggc atgttttccc
    48421 ctgccctcta gctctatatg gaacagggag tatcagattt atctggcaga ttgtatcaaa
    48481 taaggcttga aactgttttg aataggcgta tagacttgag aatttgagaa tatgtcgtct
    48541 agcagtagag acatattttc cggcaatatg aaggaagaga cgtcgaaaac gcttgatagt
    48601 caaggacttt acttcatcac cagctagctg ttttaaaaag aggtagagat tataagccag
    48661 acagcctatc atcatacgta cttcattctt aatcatggtc gaactatctg tcttatcccc
    48721 aaagaatcct gctttccttt ctttgataaa gttttcagca ttccctcgtt cacgatagaa
    48781 ttgaaacagc tcctcactat ctacactgct taaattggtc aaatgaactt ttttacaacc
    48841 ataaaaaaga gcacttaatc gtactcttct cttttaagga ttagttgaat taattcaaat
    48901 ccactagttc tcctgtttct aggtagacta ggcgttcaca aatgttagca atgtaatcag
    48961 cgaagcgttc cagatgccct atgatataaa ggtattgtgt tccattggga attgaggttt
    49021 cttggtcttt cataagtcca atgatttcct ttgataaggc ataataatat tggtcaatct
    49081 gttcatcttt ttgagcaata ctaatagctt ttgaggcttg gtgcaaagga aaggcaacca
    49141 ataaatcgga tagcatgctg agggataatt tacccatttg gtgtaactgt tcttcgtcag
    49201 gggctagttg attttctttt agttgcaaaa cagctttagc aatgcctgcc atatggtctc
    49261 ccatacgttc aaggtctgaa caagaagaca tgatgctaat cacaaatcga aggtcagaca
    49321 cttgtggctg ctgcaaggcc aacaaacggg cacaggtcaa ttcgatagcg ctttgacctt
    49381 ggttgatagc atgatcctta ttgataatta gctctgccat ctccttgtct ttggaggcta
    49441 aggccagtaa ggtttttgaa gctgtttcaa ggacaagttg ccctagtcct aaaaaggatt
    49501 gttctaattc atgcaattct aagtcaaatt gatttctcat aggtttttcc ttccttatcc
    49561 gaaccgtcct gaaatatagt cttctgtgcg ctgatctttt ggattggtaa acacgtcaac
    49621 ggtgtctcca aattcgcaaa tttctcctgt taagaaaaaa gcagttttat ctgaaatacg
    49681 tgaagcttgt tgcatgttat gggtaacaat gataatcgta taatcctttt ttagttgctg
    49741 aatgaggtct tcaattttta aagtggagat agggtctaag gctgaagtcg gctcatccat
    49801 taacagaaca tcaggttcta ctgctaaagc tcgcgcaatg caaaggcgtt gctgctgacc
    49861 gcctgataag gacatggcac tctttttaag attatctttg acttcgtccc aaatggctgc
    49921 cccttttaaa gatttttcca ctaaggcatc taattgtttt ttgtctcgaa taccatgtgt
    49981 ccttgggcca taagccacgt tatcatagat agacatggca aagggattag gctgttgaaa
    50041 aaccatccct acacgcttgc gtagctgatt aaggttgaat ttgctactat aaatatcttg
    50101 ctcatctaag aggacttggc cttcaatatg gcaagaagga accaaatcgt tcatccgatt
    50161 aagggttttt agaaaagttg atttgccaca accagatggg cctatcaagg cagtaatctg
    50221 tctttctggt aattgaatcg aaatattttt taaggcttga aaatccccgt aaaataagtc
    50281 taggtgtctg actgaaaatg ttcccatact aggaagctcc tttcacaagt ttccgagata
    50341 ataagcttga tagagtattt atcattaaaa cagtaataat caaaatcacg ccggtagcat
    50401 aggcttcatt gacatgtagc ccctcacttg acagcatata catatgtagg gctagagaac
    50461 ggcctgaaga catgagacta cttggcgtat tggtagaggt acctaatgta tacatgaggg
    50521 cagctgtttc accaacgata cggccaatag ctagtatcac tccagctaaa atacctggca
    50581 tggcaactgg tagaacaatt ctaaaaacag tccgtaactt acctgcccca agtccataac
    50641 ttgcttgacg catactatca ctaacagata aaagggcttc ttctgttgag cgaataatga
    50701 ctggcaacac catgataact gaggttaaga ttcctgataa cagagagtat tgaaaaccta
    50761 agaagactac aaagaagagc atgccaaaca gaccaaaaac aatggaagga atcccagata
    50821 aggtatctga ggccaatcgc atgattttaa cacaaaggga atcttttttt gtatattcca
    50881 caagataaaa accagcaaaa atccctatgg gcaaggctaa aagaagagca ccaaagacca
    50941 gaataacggt ggaaataatc gctggcataa gggaaatgtt ctcagaagta taagtccaag
    51001 aaaagaggga tagacttaga tgaggtaagc ctttgatgag gataaaacca atgattaaaa
    51061 agagagagcc aaaggttaaa gctgaaaaac aataaacgag aagttttagc aggtatttac
    51121 tcataagatg attttccttt caagtaggca aagtaggcat taatcaagag aataaggaaa
    51181 aagagaactg ctgaggttgc aataagggct tccctatgct gacctgatgc gtaagccatt
    51241 tccagaacaa tattggttgt taaggttctg gttcctgaaa agagtccact tggaataatc
    51301 ggctggttgc ctgccaccaa aataactgcc atggtttcac ctactgcgcg accgattcct
    51361 aaaataactg ctgataaaat accagatctc gcagctggca agatgacact aaaaatactc
    51421 cgttcatgac tagctcctag agccaagcta ccagaataat acgttttggg aactgttcgg
    51481 atagcagatt ctgacaaact gataatggtt ggcaaaatca ttattcctaa tagtaacgaa
    51541 gcggttagga cactcatgcc atttcctaaa aagcttctaa tccaaggcac caataattgt
    51601 aggccgaaaa aaccataaac aatagatgga atggctgcca tcaagttgat agctgatttt
    51661 aagaagccat agacgggctt tggacaataa taaaccataa acaccgatgt caagatgcct
    51721 gttggcaccc caatcacaat cgctcctaag gtaattaata aggaaccaac gatcattggt
    51781 aaaataccat agcttgccgg aatgttcgtt ggcgaccaat cactgcctaa taaaaaacgg
    51841 gcaaagccgt agttagctat gaaaggtaag ccattactaa aaataaagaa acagattagc
    51901 aaaatagcta caacagctac tgttgcactc atgaaaaaaa ttgccctaaa aactgcttct
    51961 ttgaaggctt gttttgtcac atcttgtcct ttctagtgaa gaaagtaagg gagatacgac
    52021 acctccctac ttgccttctt tatcttattg tacgatgaaa cgtctgcatc tctttagaga
    52081 tttatggagc aaacatttta tttaatcttg tcccaggtgg ttaatttgcc actaaaaacg
    52141 tctgcaagtt cagccatact gacttggctt gccttattgt cattattgac cacaacagca
    52201 ataccgtcta aagcaatagc atcatgggtg agactcttac cttcttcagg agttaattcc
    52261 ctagaaacca taccaatatc agcggttttc tccttaacag cggtaatacc tgctgaagac
    52321 ccattagagg taatatcaat cgtaacttct ggattttctt ttttataagc ttctgctaat
    52381 ttttccatta aagaagatac tgaagtggaa cctacaacag acaacttgcc tgataagtgt
    52441 tggcttgtat attctgtggt ttcggtttta gcttcaataa atttattatc agtgaccact
    52501 tgttgacctt gtttggagtg gataaagctg ataaaatctt gacctagctt ggaaagatta
    52561 gaagaccaaa caatgttgaa gggacgttga agagggtatt caccatctaa aactgtgtct
    52621 cgactagcct tgacaccatc aatctctaaa gccttgacag atttcgttaa agatcccaag
    52681 gagatgtagc cgatagcatt agcattccct tgaactgctg agagaacacc ttctgtacta
    52741 ttttgaatca cagctgtttt ggcagtgttg tcaatttttt tatcaccgtc ttttttgaga
    52801 atccctgtga tttctgtgaa ggcaccccgt gttccagagc cattttctcg tgaaatcacc
    52861 tcaatcgttc ctgaagctga ctgtttggaa gcagctgact gattgccaca ggcaacaagc
    52921 ccaaatcctg ataagccaat ggctgcaaga gtaagcattt ttttgaattt cataataatc
    52981 acctttatct ctatgtattt ttcttgtgta ggcttactac atttatagtc taacaagtct
    53041 ttgtaaaggt ttatccctga ttcatgtaaa gattgtgtaa agaatcaaaa aaagccactt
    53101 ttgaaaaatg gctgctccta aaaatagctt taaaaattat tagtcctgtg cgaaagattg
    53161 gttaggaaga aaaatcgtga agcaactgcc tctgccaagc tgactcgtca ccgtgacttg
    53221 gccacctaat aattgactga gttctttgac aatggcaagg ccaagaccag tgccaccagt
    53281 ttgtctgctt cgacctttat taactcggta aaaacgttca aaaatacgat cctgctctaa
    53341 ttgactaata ccaatccctg tatctgatac agaaatctta atgccttcgt tcaccttttg
    53401 ggtcttgacc tcaatttttc ccccttgttc agtgtaacgg atggcattgg ataaaagatt
    53461 gagtaagatt tgggaaagta attgactatc tgatacgagg gtgacatcat ctggcacctg
    53521 cacctttagc tgtaaatcct tcttcttgag ctgaggttgc aagctttgag tcaaatcctg
    53581 tacaaattct gccaaagaaa gggtcgtcca ttgtataggc atttgttgag ccttagataa
    53641 ggtaagaaga tgctcaacaa tatgctcaag acgcaagctt tctttgtaaa taatgtctag
    53701 aaagtcatcc ttgagcgctt cttcttcagc tgacatcccc ttaatggttt cagcaaagcc
    53761 cttaatcgaa gtaactggtg tcctcaattc atgggaggca tttgagacaa aggctaaatt
    53821 taacttttca taagttctaa tcgttgttaa atcatatagc aagacgagca cagcttccac
    53881 agattgggtg gggctaaaaa cgggaactgc tgtcacttct aaaatcaagt caccctcatg
    53941 aaacccactt acttcttgtt ttaaccttgt tttttgatca aaggcttggt gaactaaatt
    54001 tcgaatatcc atccgtttga ggtcatcaag tgaacttatg tcgccgtcca catcgggaaa
    54061 ataatgaggc agagagcgac tggataataa catctgacct tgagcggaaa ctaaaaacgt
    54121 ccccatggtt aggtgcgaca gaagaacctc cattgtttcg gctaggtcct tgtattgctg
    54181 atcctgttgg gagactttgg tttttaggcc agacacatac tgagccaaag actttaagtc
    54241 ttcttgccct ttttctaaaa agtattcact actggtcaag agaggttggt gcaaggtctc
    54301 aaaagcaact tcccatttcc aaaggcaaaa gagccagtag ccaccttgtc ccaaagaaag
    54361 ggctagaaga aagagaccga tgcctttact gatccaagtt aatgccatcc ctgcaatcag
    54421 aatgaggcta acacttagat tgactagcca aaattgaagg tagcgtttca tctataactc
    54481 cttgaactta taaccataac cccgaatggt tcgaataaat tgaggggctt taggattgtc
    54541 ttcaattttt tccctcaact taccaatatg aacgtccacc aaacgtgttt cctgcccaaa
    54601 gtcatacccc cagatacgtt ccaaaagacg ctctctagtt agtgtcatgt tgggatgttt
    54661 cataagatag agcaagagtt caaattcttt tggggtcaaa ctcagtaact tattcgcctt
    54721 gtagacttca tgacgctcag ggtatacttt caaggtccca aatagccaag aatcgtcagc
    54781 gatattatct gaatcatctc cttcttgttc tcctttagtt cgcctgagga cagccttgac
    54841 acgcgccagc aattctctag ggctaaaagg cttggtcagg tagtcatcag cccctaattc
    54901 caaggccaaa accttatcaa attcatcact tttcgcagaa accatcataa ttggagtttt
    54961 gacgcctttg gctctcagtc gcttacaaac ttccatgcca tctaattgtg gtaacatgat
    55021 atcaagcaag ataaaatcaa agggttctgt ttctgccaaa gctaaggcct tccgtccatt
    55081 tgttaccaat tgagtagaaa agccttcctt acttaaatgg tagtcaagca atttcagaat
    55141 gtgttcttca tcatccacta ataagacttg ttttgtcatc tattatctcc tattggtaac
    55201 attataacac aattatcaga aatcctaaca ttgctaaatt agattaaatt tgcttatcaa
    55261 gactagtatc tggtcaaatg ctcaatcatc tccttgtgct ctggataggt cgccagtaga
    55321 tctgcccttt caaataattc aaaatcctca aattcaaaac caggagcaac aagacaagaa
    55381 accagagcat aatccttatc aactgttgat ccccaaatag tgctcttagg aacacagtag
    55441 tgaagttgtt gccctttgga tatgtccagg actaaagtga ctgcttcgta gtgaccatct
    55501 gctgtaatca tgtgaacagt aagtggggat cctgcatgaa aataccagat ttcatctgct
    55561 gtcaatcggt gaaaatgtga aggattcgtt tcttctaata agaaataaat actggtataa
    55621 agcgcccttc ccttaccagc aaggtttata gtgtctgaag ctttttttgt ttgtctaaaa
    55681 tagccacctt caacatgggg agctaactct agagttctta tcaagtcttc tttatccatc
    55741 ggggccaatg ggttgaagta actcttgttc aaagtggtgt tacgatttca agaactcctc
    55801 tcagttctga ggacacggta atgattgatg cgacggaagt aaaaatcaat cgccctaaaa
    55861 aaagaattag cgaatgattt tggtaaaaag aaatttcacg ctatgaaggc tcaagcgatt
    55921 gtcacaagtc aagggagaat tgtttctttg gatatcgctg tgaactattg tcatgatatg
    55981 aagttgttca aaatgagtcg cagaaatatc ggacaagctg gaaaaatctt ggctgacagt
    56041 ggttatcaag ggctcatgaa gatatatcct caagcacaaa ctccacgtaa atccagcaaa
    56101 ctcaagccgc taacagctga agataaagcc tataaccatg cgctatccaa ggagagaagc
    56161 aaggttgaga acatctttgc caaagtaaaa acgtttaaaa tattttcaac aacctatcga
    56221 aatcatcgta aacgcttcgg attacgaatg aatttgatta ctggtattat caatcatgaa
    56281 ctaggattct agttttgcag gaagtctatt atttggttag gtgaattagt gaagcgttta
    56341 ggcaagtgtc tctggttacg acgtaaagaa gcataaatcg atcatattta tgtttcttta
    56401 ctagtgaaac gcctagccaa attaccatag ttacgacgtc atgacctcta aatcgattat
    56461 atttaggggt catgactagt gaagcagtta gctagttcgc atataagcgg ctagcgtcta
    56521 acaattagga actttagttc caataacttt aagattacga cgttttagga cataaatcga
    56581 tcatatttat gtcctaaaac tagtgaagcg cctagccaaa gtccgaatag gatttggcgt
    56641 tagttactta gattgctttg caatcaagta actttggcga tttacatctt ctctggcgct
    56701 tctactccaa gcaagcgaag ggcttctttg agaacgactg cggttgcgta gctgagggct
    56761 agacggctgt cgcgttctgg gctttcatcc aagatacgtg tatgtgcata gtatttgtta
    56821 aaggattgag ctaggctaat tgcaaattta gcaatgatag aaggttcaaa gttatctgcc
    56881 gcacggttga taatacgtgg gaagtcttga atgagtttaa tgatttccca gctttcagta
    56941 tcattcaagc tatagttgcc agctgtttct ggtttgaaat cggctttgcg taagatagat
    57001 tggatacgag cgtaggcata ttgaacgtaa ggtccagttt caccctcgaa ggataccata
    57061 gcctctaggt cgaagtcgta tccatttgta cggtcggttt tgaggtcata gaatttaatg
    57121 gctccaaccc caacagcatg tgctacttgg tctttgtttt ctagttcagg atttttagcc
    57181 tcgatttgga ccttggcacg gctaacagcc tctgcaacag taggctctag caagatgaca
    57241 ttccctttac gagtagagag tttcttccct tcttttgtaa ccaaaccaaa aggaacgtga
    57301 gtaatgtcgt cactccagtc gtagcccatc tcttgcaaga cagctttgag ctgtttaaag
    57361 tgggcagatt gttcttgacc aacgacatag atagatttag caaattggta ttcgttttta
    57421 cggtaaaggg ctgcagccaa gtcacgtgtg atatagagag ttgcaccatc agatttcttg
    57481 atgagagctg gatgttcaat tccgtatttc tcaagattga caacttgggc accttctgat
    57541 tcaagaagta gtcctttttc agaaagaatg tctacaactg catccatctt atcattgtag
    57601 aaggcttctc cgttatagct gtcaaattca accttcaatt cattgtaaag gcggttaaat
    57661 tccactaaac tttcatcgcg gaaccattgc caaagagcga gagcttcctc atctccattt
    57721 tcaagtttac ggaaccattc gcgcgcttct tcatccaagc tagggtcatt ttcagcttca
    57781 gcgttgatgc ggacatagag tttaaggagt tcatcgattg gatgagcttt tacagcttct
    57841 tcgtcgcccc attttttgta ggcaacaatc aacatcccaa attgtttacc ccagtctccc
    57901 aaatggttga ccttgaccgt ttgataaccg attttttgga aaatatgtga caagctatct
    57961 ccgataacag ttgaacgcag gtggccaata gaaaatggtt tagcgatatt cggactagac
    58021 atgtcgataa caacattttc ttgtttgcca atattttggt cagcatagtg ttctttttca
    58081 gtggtaacag cttgcaatac ttgagcagaa atggcagatt tatcaaggaa aaagttaacg
    58141 taaggtcctg ttgcgacaac tttttcaaag gcttggctgt tcattttttc agccagttca
    58201 gccgcaatca tttgtggtgc tttacgttcg actttggcaa gagaaaaagc agggaaagcg
    58261 atgtcaccca tttctgagtt tttaggggtt tccagtaact ttaaaatagc ctcttggtcc
    58321 aggttatcaa tgatgctagc caattcgcta gcaatcaatt cttttgtatt cattaagagc
    58381 tcctttttgg acttttctac tattttaaca caattttaaa gaaagaagaa aaaatttttg
    58441 aaatctcctg tttttttggt ataatatggt tataaatata gttataaata tgcacgcaag
    58501 aggattttat gagaaaaaga gatcgtcatc agttaataaa aaaaatgatt actgaggaga
    58561 aattaagtac acaaaaagaa attcaagatc ggttggaggc gcacaatgtt tgtgtgacgc
    58621 agacaacctt gtctcgtgat ttgcgcgaaa tcggcttgac caaggtcaag aaaaatgata
    58681 tggtgtatta tgtactagta aatgagacag aaaagattga tttggtggaa tttttgtctc
    58741 atcatttaga aggtgttgca agagcagagt ttaccttggt gcttcatacc aaattgggag
    58801 aagcctctgt tttggcaaat attgtagatg taaacaagga tgaatggatt ttaggaacag
    58861 ttgctggtgc caatacctta ttggttattt gtcgagatca gcacgttgcc aaactcatgg
    58921 aagatcgttt gctagatttg atgaaagata agtaaggtct tgggagttgc tctcaagact
    58981 tatttttgaa aaggagagac agaaaatggc gatagaaaag ctatcacccg gcatgcaaca
    59041 gtatgtggat attaaaaagc aatatccaga tgcttttttg ctctttcgga tgggtgattt
    59101 ttatgaatta ttttatgagg atgcggtcaa tgctgcgcag attctggaaa tttccttaac
    59161 gagtcgcaac aagaatgccg acaatccgat ccctatggcg ggtgttccct atcattctgc
    59221 ccaacagtat atcgatgtct tgattgagca gggttataag gtggctatcg cagagcagat
    59281 ggaagatcct aaacaagcag ttggggttgt taaacgagag gttgttcagg tcattacgcc
    59341 agggacagtg gtcgatagca gtaagccgga cagtcagaat aattttttgg tttccataga
    59401 ctgcgaaggc aatcaatttg gcctagctta tatggatttg gtgacgggtg acttttatgt
    59461 gacaggtctt ttggatttca cgctggtttg tggggaaatc cgtaacctca aggctcgaga
    59521 agtggtgttg ggttatgact tgtctgagga agaagaacaa atcctcagcc gccagatgaa
    59581 tctggtactc tcttatgaaa aagaaagctt tgaagacctt catttattgg atttgcgatt
    59641 ggcaacggtg gagcaaacgg catctagtaa gctgctccag tatgttcatc ggactcagat
    59701 gagggaattg aaccacctca aacctgttat ccgctacgaa attaaggatt tcttgcagat
    59761 ggattatgcg accaaggcta gtctggattt ggttgagaat gctcgctcag gtaagaaaca
    59821 aggcagtctt ttctggcttt tggatgaaac caaaacggct atggggatgc gtctcttgcg
    59881 ttcttggatt tatcgcccct tgattgataa ggaacgaatc gtccaacgtc aagaagtagt
    59941 gcaggtcttt ctcgaccatt tctttgagcg tagtgacttg acagacagtc tcaagggtgt
    60001 ttatgacatt gagcgcttgg ctagtcgtgt ttcttttggc aaaaccaatc caaaggatct
    60061 cttgcagttg gcgactacct tgtctagtgt gccacggatt cgtgcgattt tagaagggat
    60121 ggagcaacct actctagcct atctcatcgc acaactggat gcaatccctg agttggagag
    60181 tttgattagc gcagcgattg ctcctgaagc tcctcatgtg attacagatg ggggaattat
    60241 ccggactgga tttgatgaga ctttagacaa gtatcgttgc gttctcagag aagggactag
    60301 ctggattgct gagattgagg ctaaggagcg agaaaactct ggtatcagca cgctcaagat
    60361 tgactacaat aaaaaggatg gctactattt tcatgtgacc aattcgcaac taggaaatgt
    60421 gccagcccac tttttccgca aggcgacgct gaaaaactca gaacgctttg gaaccgaaga
    60481 attagcccgt atcgagggag atatgcttga ggcgcgtgag aagtcagcca acctcgaata
    60541 cgaaatattt atgcgcattc gtgaagaggt cggcaagtac atccagcgtt tacaagctct
    60601 agcccaagga attgcgacgg ttgatgtctt acagagtctg gcggttgtgg ctgaaaccca
    60661 gcatttgatt cgacctgagt ttggtgacga ttcacaaatt gatatccgga aagggcgcca
    60721 tgctgtcgtt gaaaaggtta tgggggctca gacctatatt ccaaatacga ttcagatggc
    60781 agaagatacc agtattcaac tggttacagg gccaaacatg agtgggaagt ctacctatat
    60841 gcgtcagtta gccatgacgg cggttatggc ccagctgggt tcctatgttc ctgctgaaag
    60901 cgcccattta ccgatttttg atgcgatttt tacccgtatc ggagcagcag atgacttggt
    60961 ttcgggtcag tcaaccttta tggtggagat gatggaggcc aataatgcca tttcgcatgc
    61021 gaccaagaac tctctcattc tctttgatga attgggacgt ggaactgcaa cttatgacgg
    61081 gatggctctt gctcagtcca tcatcgaata tatccatgag cacatcggag ctaagaccct
    61141 ctttgcgacc cactaccatg agttgactag tctggagtct agtttacaac acttggtcaa
    61201 tgtccacgtg gcaactttgg agcaggatgg gcaggtcacc ttccttcaca agattgaacc
    61261 gggaccagct gataaatcct acggtatcca tgttgccaag attgctggct tgccagcaga
    61321 ccttttagca agggcggata agattttgac tcagctagag aatcaaggaa cagagagtcc
    61381 tcctcccatg agacaaacta gtgctgtcac tgaacagatt tcactctttg atagggcaga
    61441 agagcatcct atcctagcag aattagctaa actggatgtg tataatatga cacctatgca
    61501 ggttatgaat gtcttagtag agttaaaaca gaaactataa aaccaagact cactagttaa
    61561 tctagctgta tcaaggagac ttctttgaca attctccact tttttgctag aataacatca
    61621 cacaaacaga atgaaaagga gctgacgcat tgtcgctccc ttttgtctat tttttaagga
    61681 gaaagtatgc tgattcagaa aataaaaacc tacaagtggc aggccctggc ttcgctcctg
    61741 atgacaggct tgatggttgc tagttcactt ctgcaaccgc gttatctgca ggaagtctta
    61801 ggcgccctcc ttactgggaa atatgaagct atttatagta tcggggcttg gttgattggt
    61861 gtggccgtag tcggtctagt tgctggtgga ctcaatgttg tcctcgcagc ctatattgcc
    61921 caaggagttt catccgacct tcgggaggat gccttccgta aaattcaaac cttttcttat
    61981 gctgatattg aacaatttaa tgcgggaaat ctagtcgttc gaatgacaaa tgatatcaac
    62041 cagattcaga acgttgtcat gatgaccttc caaattcttt tcagacttcc cctcttgttc
    62101 atcggttcgt ttatcctagc ggttcaaacc ttaccttctc tgtggtgggt gattgttctc
    62161 atggtagtct tgatttttgg tttgactgct gtcatgatgg gaatgatggg gcctcgtttt
    62221 gccaagtttc aaacccttct tgagcgcatc aatgccattg ccaaggaaaa tttacgtggc
    62281 gttcgtgtgg tcaagtcctt tgtccaagaa aaagagcaat ttgctaagtt tacagaggtc
    62341 tcagacgagc ttcttggtca aaacctttac attggttatg ccttttcagt agtggaaccc
    62401 tttatgatgt tggttggtta cggggcggtc ttcctctcta tttggctggt cgcgggaatg
    62461 gttcagtcgg atccgtctgt tgttggttcc atcgcttctt ttgttaatta cctaagccag
    62521 attatcttta ccattgttat ggttggattt ttgggaaatt ctgtcagccg tgccatgatt
    62581 tccatgcgtc gtattcgaga aattcttgac gcagagccag ctatgacctt caaggatatc
    62641 ccagatgaag agttggttgg aagccttagc tttgaaaatg tgacctttac ctatccaatg
    62701 gacaaggaac cgatgctgaa agatgtgagc tttactattg aacctggtca aatggttggt
    62761 gtagttggag cgactggtgc aggaaagtca accttggctc aattgattcc acgtctcttt
    62821 gatccacagg aaggggctat caaaatcgga ggtaaggata ttcgagaagt gagtgaagga
    62881 accctgcgta aaacagtttc catcgttctc caacgtgcca ttctttttag tggaacgatt
    62941 gcagataact tgagacaggg gaagggaaat gctactctat ttgaaatgga gcgcgcagcc
    63001 aatattgccc aggctagtga attcattcat cgtatggaga aaacctttga aagtccagtt
    63061 gaagaacggg gaaccaattt ctctggtgga caaaaacaaa ggatgtcgat tgcgcgtggg
    63121 attgtcagca atccacgtat tctgattttt gatgattcga cctcagcctt ggatgccaaa
    63181 tcagagcgct tggtgcaaga agctttgaat aaggacttga aggggacgac aaccattatt
    63241 attgctcaaa aaattagctc ggttgtccat gcagacaaga tcttggttct aaatcaagga
    63301 cgattgattg gtcaaggcac gcatgcagac ttggttgcca acaatgccgt ttaccgtgaa
    63361 atctatgaaa cacagaaatg aaagacaaac tataagaaaa gtcaatagtt ttatctaaac
    63421 tatttcttat ttcaatttga tgatttggcg atgattttag agcacggcaa aaagctattg
    63481 aaaaagtcca ttttttcaaa ggtaatcctg tgttaatttc agaaattata tcactttttg
    63541 ttcgtcaaat ggcagctctt ttttaggata taaaacaggg ttcggataag tttttttgca
    63601 aggtggatga tggctacatt gtaatgtttt ccttattcta acttagtctt aagataggcc
    63661 ttaaaagcag gtgaaaagcg agggcatgct ttggcagctt gtatgagtac ctaccgcaga
    63721 tgaggggaac cccgtttgac cattcttcct gctaaatcaa tctgacctga ctgataaata
    63781 gaagaatcca gtccagcgaa agcttgtaat tgagcaggat tatcaaaggc atgaatattt
    63841 cgaatctcgg ctaaaatgac cgcccctaaa cgattctcaa tcccagtaac cgtcgtgatg
    63901 accgagttga actcagccat caagtcattg acacattttt tcgccttgtc aatgagcctc
    63961 ttgtaatgtt tgatgatttc attacacgag ataaaacgtc tatgcgttat caaactcatt
    64021 accaattaaa acaaaaagct gtggttagat cctttcggaa atcgtcaagc gattggagga
    64081 aatgaactaa tccacagcgg cttattccaa gtataccact tgggctttgg cagtagctaa
    64141 ctgcgctaaa tataatataa ggaggagtaa aatgaagaca gttcaatttt tttggcatta
    64201 ttttaaggtc tacaagttct catttgtagt tgtcatcctg atgattgttc tggcgacttt
    64261 tgcccaagcc ctctttccag tcttttctgg acaagcggtg acgcagctag ccaatttagt
    64321 tcaagcttat caaaatggca atccagaact tgtatggcaa agcctatcag gaatcatggt
    64381 caatcttggc ctgctggttt tggttctatt tatctctagt gtaatataca tgtgtctcat
    64441 gacgcacgtg attgcagaat cgaccaacga gatgcgcaaa ggcctctttg gtaagcttgc
    64501 tcagttgacg gtttctttct ttgaccgtcg acaagatggc gatatcctgt ctcattttac
    64561 cagtgatttg gataatatcc tccaagcctt taacgaaagc ttgattcagg tcatgagcaa
    64621 tattgtttta tacattggtc tgattcttgt catgttttcg agaaatgtga cgctggctct
    64681 catcaccatt gccagcaccc cattggcttt ccttatgctg attttcatcg tgaaaatggc
    64741 acgcaaatac accaacctcc agcagaaaga ggtagggaag ctcaacgcct atatggatga
    64801 gagcatctca ggccaaaaag ccgtgattgt gcaaggaatt caagaggata tgatggcagg
    64861 atttcttgaa caaaatgagc gcgtgcgcaa ggcaaccttt aaaggaagaa tgttctcagg
    64921 aattcttttc cctgtcatga atgggatggg cctgattaat acagccatcg tcatctttgc
    64981 tggttcggct gtacttttga atgataagtc tattgaaaca agtacagccc taggtttgat
    65041 tgttatgttt gcacaatttt cacagcagta ctaccagcct attatccaag ttgcagcgag
    65101 ttggggaagc cttcagttgg cctttactgg agctgaacga attcaggaaa tgtttgatgc
    65161 agaggaggaa atccgacctg aaaaggctcc aaccttcact aagttgcaag aaagtgttga
    65221 aatcagtcat atcgattttt catacttgcc tgataaacct attttgaaag atgtcagcat
    65281 ttctgcccct aaaggccaga tgacagcagt tgttgggccg acaggttcag gaaaaacgac
    65341 tattatgaac ctcatcaatc gcttttatga tgttgatgct ggtggtattt attttgatgg
    65401 taaagacatt cgtggctatg acttagatag tcttagaagc aaggtgggaa ttgtattgca
    65461 agattcggtc ttgtttagcg gaacgattcg agacaatatc cgatttggtg tgccagatgc
    65521 tagtcaggaa atggttgagg tagcagcaaa agcaacccac attcacgact atatcgaaag
    65581 tttgcctgat aagtacgata ctcttattga tgatgaccag agcatctttt caacagggca
    65641 gaagcaattg atttcaatcg ctcgaaccct gatgacagat ccagaagttc tcattctcga
    65701 tgaagcaact tcaaacgtag atacggtgac agaaagcaag attcagcatg ccatggaggt
    65761 ggttgtagca ggtagaacta gtttcgtcat tgcccaccgc ttgaaaacca ttctcaatgc
    65821 agatcagatt attgtcctta aagatggaga agtcattgaa cgtggtaacc accatgaact
    65881 tttgaagcta ggtggctttt attcagaact ctatcacaat caatttgttt tcgaataaga
    65941 aagaagttgt cctatgtggg cagctttttc ttgtccataa aaaatgttta tcacagcctt
    66001 aaaaaaaaca tattagacga aagtcatttt gagtgatatg ataggactat cgttagcatt
    66061 cgaaaggaga ggcatcatgg ctagaacggt tgtaggagtt gctgcaaatc tatgtcccgt
    66121 agacgcagaa ggcaaaatca ttcattcatc tgtatcttgt agattcgcag agatcattcg
    66181 tcaagtcggt ggtctccctt tagtcattcc tgttggtgat gagtcagttg tacgtgatta
    66241 tgtggaaatg attgacaaac tcattttgac aggaggccaa aatgttcatc ctcagtttta
    66301 tggagagaaa aagaccgtcg aaagcgatga ttacaatctg gtccgtgacg aatttgaatt
    66361 ggcactcttg aaggaagcgc ttcgtcagaa taaaccaatt atggcaatct gtcgcggtgt
    66421 ccaacttgtc aatgttgcct ttggtggaac cctcaatcaa gaaatcgaag gtcactggca
    66481 aggactacct ttcgggacat ctcactctat tgagacagta gaaggaagcg tggtggctaa
    66541 gctatttggg aaagaaagtc aggtcaactc agtccatcgt caaagcatta aagatttggc
    66601 acctaatttc cgtgtaactg ccattgattc aagagaccaa actattgaag cgattgagtc
    66661 tatcgacgag caccgcatta tcggtttaca gtggcatcca gagtttctgg ttaatgaaga
    66721 agatggcaat ttagaattat ttgagtattt attgaatgaa ctgtaacgat tggaacatct
    66781 ggtcgttctt tcttttattt tttcaaaatt tttagaatgt ggcattttac gcaaacgttt
    66841 gaattctgat aaaaattgga gaaattcgac aaaaaaactt gaaaaaaacg aaggtaagcg
    66901 ttatgataga aaagaagaaa tattggagga agaacatgtc acatattaaa tttgattatt
    66961 caaaagtttt agacaaattt gttgcaccac atgaagtgga atacatgcaa tcacaagtaa
    67021 cagcagcaga tgaattgatc cgtaaaggaa ctggtgctgg tagcgacttc ttgggatggt
    67081 tggaccttcc tgaaaaatac gaccgcgaag aatttgaccg catcttgaaa gctgctgagc
    67141 aaatcaagtc agacagcgat gttttggttg tgatcggtat tggtggatct taccttggtg
    67201 caaaagcagc aatcgacttc ttgaatcacc attttgctaa cttgcaaaca aaagaagaac
    67261 gcaaagctcc acaaatcctt tacgcaggaa actcaatctc atctacttac cttgctgact
    67321 tggtagagta tgttgcagac aaagacttct cagtaaacgt aatttctaaa tcaggtacaa
    67381 caactgaacc agcgattgct ttccgtgtct ttaaagaact cttggttaag aaatacggtc
    67441 aagaagaagc taacaaacgt atctatgcaa caactgaccg ccaaaagggt gctgttaagg
    67501 ttgaagcaga cgctaacggt tgggaaacat ttgttgttcc agatgatatc ggtggacgct
    67561 tctcagtatt gacagccgtt ggtttgcttc caatcgcagc atcaggagct gacatcaaag
    67621 ctcttatgga aggtgcgaat gcagctcgca aagactacac ttcagacaaa atctctgaaa
    67681 acgaagctta ccaatacgca gccgttcgta acatccttta tcgtaaaggc tatgcaactg
    67741 agatcttggt aaactatgag ccatcacttc aatacttctc agaatggtgg aaacaattgg
    67801 ctggtgaatc agaaggaaaa gaccaaaaag gtatctaccc aacttcagcc aacttctcaa
    67861 ctgacttgca ctcacttggt caatttatcc aagaaggaac tcgtatcatg tttgaaacag
    67921 ttgtccgtgt tgacaaacct cgtaaaaacg tgcttattcc tactttggaa gaagaccttg
    67981 acggacttgg ttaccttcaa ggaaaagacg ttgactttgt aaacaaaaaa gcaactgacg
    68041 gtgttcttct tgcccacaca gatggtgatg taccaaacat gtatgtgact cttccagagc
    68101 aagacgcttt cactcttggt tacactatat acttcttcga attggcaatt gccctttcag
    68161 gttacttgaa tgctatcaac ccatttgacc aaccaggtgt tgaagcttat aaacgtaaca
    68221 tgtttgccct tcttggaaaa ccaggatttg aagaattgag caaagaactt aacgcacgtc
    68281 tataatagaa gaaaagagtg gtttgcccac tctttttact ctctttatcc atagaaattg
    68341 gactcagcca agacttgtga tataatatag aaagcaaaaa ggcagacgcc tagataatag
    68401 gagaaactat gtcaaaagat atccgcgtac gttacgcacc aagtccaaca ggactactac
    68461 acatcggaaa tgctcgtaca gcattgttta attacttgta tgcgcgccat catggtggaa
    68521 catttctcat ccgtatcgaa gatactgacc gtaaacgcca tgtcgaggat ggtgaacgtt
    68581 cacaacttga aaaccttcgc tggttaggca tggattggga tgaaagtcca gaatcacatg
    68641 agaattatcg ccagtctgag cgtttagact tgtatcaaaa atacattgac caactattag
    68701 ctgaaggaaa agcctataaa tcttacgtta cagaagaaga gttggcagct gaacgcgaac
    68761 gccaagaagt agctggcgaa acaccacgct acatcaatga ataccttggt atgagtgaag
    68821 aagaaaaagc agcttacatc gcagaacgtg aagcagcagg gatcatccca actgttcgtt
    68881 tggctgtcaa tgagtcaggt atctacaagt ggcatgatat ggtcaaaggc gatatcgaat
    68941 ttgaaggtgg caatatcggt ggtgactggg ttatccaaaa gaaagacggt tacccaactt
    69001 acaactttgc cgttgttatc gatgaccacg atatgcaaat ctctcatgtt atccgtggag
    69061 atgaccatat tgctaataca ccaaaacagc ttatggtcta tgaagctctt ggttgggaag
    69121 ctccagagtt cggtcacatg accttgatta tcaactctga gactggtaag aagttatcta
    69181 aacgtgatac taatacactt caatttatcg aagattaccg aaagaaaggt taccttccag
    69241 aagcagtctt taactttatt gctcttcttg gttggaaccc aggtggtgaa gatgagattt
    69301 tctctcgtga agaactcatt aaactttttg atgaaaaccg cctcagcaag tcaccagcag
    69361 cctttgatca gaaaaaacta gactggatga gcaatgatta tatcaagaat gcagaccttg
    69421 aaaccatctt tgaaatggca aaaccattct tagaggaagc aggccgtttg actgacaagg
    69481 ctgaaaaatt agttgagctc tataaaccac aaatgaaatc agtagatgag attatcccat
    69541 tgacagatct tttcttctca gatttcccag aattgacaga agcagagcgc gaagtcatga
    69601 cgggtgaaac agttccaaca gttcttgaag cattcaaagc aaaacttgaa gcgatgacag
    69661 atgatgaatt tgtgacagaa aatatcttcc cacaaattaa agcagtccaa aaagaaacag
    69721 gtattaaagg gaaaaatctt ttcatgccta ttcgtatcgc agtttcaggc gaaatgcatg
    69781 ggccagaatt accagataca attttcttgc ttggacgtga aaaatcaatt cagcatatcg
    69841 aaaacatgct aaaagaaatc tctaaataaa gaggatacaa taatggacat ctgggaaaag
    69901 atgtacgaag aagcacagaa actatacaat ccacatgaag tatcagactt tgtttatgcc
    69961 aatcatgttg tagctgcagt agaagcagga gatggacaaa tatttacagg attctgtatg
    70021 gagggaacct gtggtgtttt ccatctctgc gcagaacggg cggccctctt caatatgtac
    70081 caattttcag gacaaactaa ggttaagaaa gtattagcct ttcgagacaa accaccttat
    70141 ggtggaagtt cagccatgcc ttgcggtgct tgtagagaat tccttttaga gtttaatgct
    70201 gaaaataaag atgcagaatt catgatggac tataatataa gaaaaacagt taaagtcgca
    70261 gaactaatcc cttattggtg gggagaagaa cgtgcttcta agtttaatga gcgatagaag
    70321 agtcagtata attctggctt tttttactat aagttgaaaa aataaaaaaa aattagaaaa
    70381 agt
//
LOCUS       DAVLXH010000005        65014 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00028199
            SAMN33607166-rid17955573.denovo.005, whole genome shotgun sequence.
ACCESSION   DAVLXH010000005 DAVLXH010000000
VERSION     DAVLXH010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607166
            Sequence Read Archive: SRR23725544
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 65014)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 65014)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721421.1
            Genome Coverage       :: 115x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:42:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,210
            CDSs (total)                      :: 2,161
            Genes (coding)                    :: 2,023
            CDSs (with protein)               :: 2,023
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 73 of 138
            Pseudo Genes (incomplete)         :: 60 of 138
            Pseudo Genes (internal stop)      :: 40 of 138
            Pseudo Genes (multiple problems)  :: 31 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..65014
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607166-rid17955573.denovo.005"
                     /strain="AUSMDU00028199"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1349"
     gene            <1..194
                     /locus_tag="VYO11_000334"
     CDS             <1..194
                     /locus_tag="VYO11_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000810873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1594946.1"
                     /translation="DVKKNYLQLVTTATSDNMSVIEFEMEKESDLYYFIKATLGSSFS
                     RMHYSVLVKALAGALAKNI"
     gene            254..475
                     /locus_tag="VYO11_000335"
     CDS             254..475
                     /locus_tag="VYO11_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000475753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1594947.1"
                     /translation="MFKNFCQNAFISLYFIVSALGGFSARLEFRSFSPYQSMKVALLL
                     GVILILLQLPIMFAKLLEALKIKKGETHE"
     gene            691..2004
                     /locus_tag="VYO11_000336"
     CDS             691..2004
                     /locus_tag="VYO11_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000472769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsK"
                     /protein_id="HEV1594948.1"
                     /translation="MFKIKQTASLSEHYFLNTSKLRSIRWFTIGFLSILSFSSSILFK
                     GWFLQMITLSVELIIILYIERKIKGWAQQIEPLLIVRENLLFMLRRNSFLFTATKDGA
                     ILRSAKFNYQLNDVSIVVHALKSGDEFTKEMETLDVFLSSTLGISLSSKEIYATHVEY
                     VFVYKQPERLYVTSLPLEDDSLKIKIYDDFVIDLRKNFSMLISGASGSGKSFFTYYYL
                     TRFISQTVNGKHAKIYVIDPKFSDIYKLCEFSGFPVENYGTTNEDAFRILRQYIKELD
                     RRMLIYNQSNLFNSIGIDLGFPPLLLVIEEYSSLVSSMDSKAKKDFENMVAIVAQKAR
                     SLSMGVCIVMQQPRSDSLSTNIREQLVNAIFLGAPTRESSQMMFGTTDVPNVKKDKGV
                     GLCSTDRESPKEFQAPIFNRDVFETILPVWECAAKNYMKDEDENV"
     gene            2331..2591
                     /locus_tag="VYO11_000337"
     CDS             2331..2591
                     /locus_tag="VYO11_000337"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1594949.1"
                     /translation="MKETVVVLAISTKKERGWIKVSTLNDCWSDLGMHFDKSKFGAVF
                     SAPGLYEVEVINNASFGQNAQYEVIQSRKLGTFAELIEQVKN"
     gene            2720..3763
                     /locus_tag="VYO11_000338"
     CDS             2720..3763
                     /locus_tag="VYO11_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001031657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HEV1594950.1"
                     /translation="MNKEVLNRAPSNSPITIHQMSNKSYSKFQEEVSLKYGFIGLKLD
                     KLSLTAEVSEEFHSEILSGNFTLYDYFGVVEPNLNRNGELASYKGQFFNDEKENWYIE
                     YTPVASIKMNKRPLKIEFTPSKVSKKNFLIVFHRMFPYMFNIAISTFHLAYDFERDLS
                     ALRVNWPKVMYRPIYKGMKLETMDFGAPKGNYHLTAYNKLKERMDSGDMAEIEIYQQY
                     DNLWRIEYKFYNEGNIKKELKNGLPFLAKIPVYIENFKGLEFNNLGVNEKIYLFALRN
                     KPELFAESDKRTVAKYKKLAESISEVNLNVFFQNALDFVEIFNQEPCLINFFEFMNSM
                     LQGDIPKLTINQE"
     gene            3779..3961
                     /locus_tag="VYO11_000339"
     CDS             3779..3961
                     /locus_tag="VYO11_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HEV1594951.1"
                     /translation="MKDTISNKDLISMGYRPSTANAIIHQARELLVSRGYTFYNRKRL
                     MVVPKSVVKELLGMEL"
     gene            3963..5090
                     /locus_tag="VYO11_000340"
     CDS             3963..5090
                     /locus_tag="VYO11_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000323402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEV1594952.1"
                     /translation="MAYIEYRQRGKKKLWSFSIRERSKSLLHKSGFKTKREAKIEAEK
                     VLHKLNTGSVLSSSMTLSELYNEWLDLKILPSNRSVVTKKKYLMRKKVIERLFGNKPV
                     SQIKPSEYQKIMNEYGETVSRNFLGRLNSSIQASIQMAIADKVIIEDFTAYVELFSSK
                     SGQKVEEKYLHTESDYQKVLVYLKNKFDYQKSIVPYVIYFLFKTGMRFSELIALTWDE
                     VDELNEQLKTYRRYNTAIHKFTPPKNNTSIRLVPITSDMLSLLKTLKILQLKTNKELN
                     IDNENNLIFQHFGYVYDVPDIATVNKAIKVMLKELQIFPLITTKGARHTYGSYLWHNN
                     IDLGVIAKILGHKDISMLIDVYGHTLEEKISEEFMAVKSLL"
     gene            complement(5171..5243)
                     /locus_tag="VYO11_000341"
     tRNA            complement(5171..5243)
                     /locus_tag="VYO11_000341"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(5208..5210),aa:Lys,seq:ctt)
     gene            complement(5508..6779)
                     /locus_tag="VYO11_000342"
     CDS             complement(5508..6779)
                     /locus_tag="VYO11_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001113185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HEV1594953.1"
                     /translation="MPDNLALRMRPKTIDQVIGQEHLVGPGKIIRRMVEANRLSSMIL
                     YGPPGIGKTSIASAIAGTTKYAFRTFNATVDSKKRLQEISEEAKFSGGLVLLLDEIHR
                     LDKTKQDFLLPLLESGLVIMIGATTENPFFSVTPAIRSRVQIFELEPLSNQDVKEALQ
                     IALSNPERGFNFPIELDEDALDFIATSTNGDLRSAFNSLDLAVLSTPENDEGIRHITL
                     DIMENSLQRSYITMDKDGDGHYDVLSALQKSIRGSDVDASLHYAARLIEAGDLPSLAR
                     RLTVIAYEDIGLANPEAQIHTVTALDAAQKIGFPEARILIANVVIDLALSPKSNSAYV
                     AMDKALADLKTSGHLPIPRHLRDGHYSGSKELGNAQDYLYPHNYPGNWVKQDYLPEKI
                     RNHHYFQAEDTGKYERALAQRKEAIDHLRKI"
     gene            7049..7288
                     /locus_tag="VYO11_000343"
     CDS             7049..7288
                     /locus_tag="VYO11_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000818079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1594954.1"
                     /translation="MKREVISNGNDGPSQEILIFTKQIRHWILSDQVISGKRKLFFRE
                     DTPKEILDLYENIKSKLDFAYQEVHSNNGLKKYEK"
     gene            7453..7632
                     /locus_tag="VYO11_000344"
     CDS             7453..7632
                     /locus_tag="VYO11_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1594955.1"
                     /translation="MNLIFEEYQFVKIGDKKYRVRSGPMIHSTPPQSVLDRDTFTIDY
                     TDDELLDKEAVFTTH"
     gene            7775..7948
                     /locus_tag="VYO11_000345"
     CDS             7775..7948
                     /locus_tag="VYO11_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000192224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
                     /protein_id="HEV1594956.1"
                     /translation="MTQKEMVKLLTAHGWIKTRGGKGSHIKMEKQGERPITILHGELN
                     KYTERGIGKQAGL"
     gene            7985..8437
                     /locus_tag="VYO11_000346"
     CDS             7985..8437
                     /locus_tag="VYO11_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000961815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HEV1594957.1"
                     /translation="MLVTYPALFYYDDTDGTEATYFVHFPDFEYSATQGEGISEALAM
                     GSEWLGITVADLIESDGELPQPSDINSLSLIDNDPFKDDEDFVSTYDLDKSFISMVSV
                     DVSEYLGSQEPIKKTLTIPKWADKLGREMGLNFSQTLTDAIADKKVQA"
     gene            8728..9198
                     /locus_tag="VYO11_000347"
     CDS             8728..9198
                     /locus_tag="VYO11_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HEV1594958.1"
                     /translation="MATYGFLDILEEELDKNFPFDFEISWDKRNHAVEVSFLLEAQNA
                     AGVEMVDEDGEVLSDDILFEEAVLFYNPAKSTVNEEDYLTVIPYLPKKGFSREFLAYF
                     ALFLKDTAEVGLDVLMDFLEDPEAEEFVMEWNQEVFEEGKVGLEEGEFYPYPRY"
     gene            9217..10320
                     /locus_tag="VYO11_000348"
     CDS             9217..10320
                     /locus_tag="VYO11_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000719717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-2 protease family protein"
                     /protein_id="HEV1594959.1"
                     /translation="MKKIGTYLVYVLAVVFIMLAFACGTIAFAELGYSAVLAFTFGYA
                     FALLSMYLIFILHELGHAFCGYLTGYRLVAFGLGHFILTKKSGRFHLSRTAILKNVGA
                     QYIGLKEDESDQRIILMLSGGLMVHLGLILLAIVFGFLTRSWYFAGTWIFLNLSFFLN
                     NILPVDITDGAKIWELLQHPENTKYAYLVLRHSAQTLLAPQEYDLKDFVQAVPEDARG
                     SFADGVLGMQGEVSILEGKEEVAKQQFQALLERATTPMMQTVAQLSLLHIALLEGDFE
                     QAEQYASIRQVKSFLSLKLSNLQVIQAWYQLKVKKDVDRTRKALKIARQKMDSSRMLR
                     DEKRYYENLLAELEKEMLEGTEDGTRNFWFPRL"
     gene            10286..10714
                     /locus_tag="VYO11_000349"
     CDS             10286..10714
                     /locus_tag="VYO11_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEV1594960.1"
                     /translation="MELEISGFPGCKIALFCEDKLLTILRDDKASIPWANMWELPGGG
                     REGDESPFECVAREVYEELGIHLTEDCLLWSKVYPSMLFADKQSVFLVGQLTQNQFDS
                     IVFGDEGQGYQLMNVEEFLSSSQVVPQLQERLKDYLKVSD"
     gene            10852..11802
                     /locus_tag="VYO11_000350"
     CDS             10852..11802
                     /locus_tag="VYO11_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000451122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HEV1594961.1"
                     /translation="METWQELKVTVKREGEELVSNLLIELGAQGVAIEDSMDYVGNVD
                     RFGEIFPEVEQQEEIVVTAYYPDTVDVTVVEADLQARISELTDFMDLGELKIGTTALA
                     EEDWADNWKKYYEPARITHDLTIVPSWTDYEATAGEKIIKLDPGMAFGTGTHPTTKMS
                     LFALEQVLRGGETVLDVGTGSGVLSIASSLLGAKEIFAYDLDDVAVRVAQENIELNPG
                     MENIHVAAGDLLKGVEIEADVIVANILADILIHLIDDAYRLVKDEGYLIMSGIIKDKW
                     DMVRQSAESAGFFLETHMVQGEWNTCVFKKTKDISGVIGG"
     gene            11804..12547
                     /locus_tag="VYO11_000351"
     CDS             11804..12547
                     /locus_tag="VYO11_000351"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001188214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HEV1594962.1"
                     /translation="MQQYFVKGSAISPVTIEDKETSKHMFQVMRLKEEDEVTLVFDDG
                     IKRLARVLDMENRQFELVQELNDNVELPVQVTIASGFPKGDKLEFIAQKVTELGASQI
                     WAFPADWSVAKWDGKKLGKKVEKLEKIALGAAEQSKRNIVPSIKLFEKKADFLAQLDQ
                     FDFIIVAYEESAKEGEAAALLQAVTGLETGAKLLFIFGPEGGLSPAEIESFEAKGAVL
                     VGLGPRILRAETAPLYALSALSVLVELEK"
     gene            12558..14354
                     /gene="pepF"
                     /locus_tag="VYO11_000352"
     CDS             12558..14354
                     /gene="pepF"
                     /locus_tag="VYO11_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HEV1594963.1"
                     /translation="MEQKHRSEFPEKELWDLTALYQDREDFLRAIEKAREDINQFSRD
                     YKGNLHTFEDFEKAFAELEQIYIQMSHIGNYAFMPQTTDYSNDEFANIAQAGMEFETD
                     AGVALTFFDDALVVADEEVLDRLGELPHLTAAIRQAKIKKAHYLGADVEKALTNLGEV
                     FYSPQDIYTKMRAGDFEMADFEAHGKTYKNSFVTYENFYQNHEDAEVREKSFRSFSEG
                     LRKHQNTAAAAYLAQVKSEKLLADMKGYDSVFDYLLAEQEVDRVMFDRQIDLIMKDFA
                     PVAQRYLKHVAKVNGLEKMTFADWKLDLDSALNPEVTIDDAYDLVMKSVEPLGQEYCQ
                     EVARYQEERWVDFAANSGKDSGGYAADPYRVHPYVLMSWTGRLSDVYTLIHEIGHSGQ
                     FIFSDNHQSYFNAHMSTYYVEAPSTFNELLLSDYLENQSNDPRQKRFALAHRLTDTYF
                     HNFITHLLEAAFQRKVYTLIEEGETFGASKLNSIMKEVLTDFWGDAIEIDDDAALTWM
                     RQAHYYMGLYSYTYSAGLVISTAGYLHLKNSETGAEDWLNLLKSGGSKTPLESAMIIG
                     ADISTDKPLRDTIQFLSDTVDQIIAYSAELGE"
     gene            complement(14414..15091)
                     /locus_tag="VYO11_000353"
     CDS             complement(14414..15091)
                     /locus_tag="VYO11_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000433071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1594964.1"
                     /translation="MEPDIFIITKLLSDPSRMHILDILMDGKAHTVNEIASFTKIKQH
                     TVSYHLKLLTEAQVTTLQTYGRFHYYSLKSAAIAEMLEFLSFYSPQRDVKSYKQHIHK
                     KELKVARTCYDHIAGELGISITNYLLQENLLSESEKDFQLTEAGKSYFQRKLHIDTDE
                     LKKKKRKFCPKCLDWSERKNHVGGALGNALLEFFSEKQLVIPAQTPRSLTITEKGKEF
                     LEKEWGI"
     gene            15338..16108
                     /locus_tag="VYO11_000354"
     CDS             15338..16108
                     /locus_tag="VYO11_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000966490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1594965.1"
                     /translation="MLYLWGKERVKKLSVKNLKKQYGSYEAVKGISFELGEGECLGIL
                     GINGAGKTSTLKMIYSLTSISSGEIDILGQNIETNRRKSKSCLGIVGQEDMLDMTLNV
                     YDNLFAHGLCYGISSVELRKRIDSLLDFVQLSKHAQKMVNQLSGGMRRRLVLARALIN
                     RPDIIILDEPTVGLDIQSRNIIWDKLLELNELGVSIIITSHYMNEIEYLTDRVLMLHQ
                     GTIKEEGTVEDLLIKYDADNLETLFLGLTGTEKEDLHV"
     gene            16101..16865
                     /locus_tag="VYO11_000355"
     CDS             16101..16865
                     /locus_tag="VYO11_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1594966.1"
                     /translation="MFKLSFHSIGHVVVRNYMSFRNLFKISIVPNLIDPLFYLLAMGF
                     GVGAYLTHVNGMLYRDFVITGLIAATAMSAATAETTVNAFIQYKIEKTYDAMLLTPIN
                     TNDIVVGQAIWAGIRAVIFGGIFWLISILITAHFHVLMLLIPLILFIVGYLFGVLGLI
                     FTYLAPSREFLNYYNVLAIRPLYMFSDTFFPITSLPPILGDLTWFSPLYHATRMIRII
                     WGGEVTGLYLHLIWLIALALLITVLPMYMLHRRYYR"
     gene            17290..17844
                     /locus_tag="VYO11_000356"
     CDS             17290..17844
                     /locus_tag="VYO11_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2785 domain-containing protein"
                     /protein_id="HEV1594967.1"
                     /translation="MYQDLLRKIAEEKPNYNQEEIQWLFDHLGNPSPEIRNVLLNQGL
                     HYLSKEKDTTGFSSQYGWVHSFAHGADLLTEVVCHPDFPINRIHEVFDILGQLFKRMS
                     ILFTDDEDWRLARVIYEPILQGKLEQEQVASWIKTVDFPIEEREDFYKFSNFRSCLVE
                     VYVQLDQRNSLQDDLKEAIQSFQY"
     gene            17955..18623
                     /locus_tag="VYO11_000357"
     CDS             17955..18623
                     /locus_tag="VYO11_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin"
                     /protein_id="HEV1594968.1"
                     /translation="MKKFVAELIGTFMLVFVGTGAVVFGNGLDGLGHLGIAFAFGLAI
                     VVAAYSIGTVSGAHLNPAVSIAMFVNKRLSSSELVNYILGQVVGAFIASGAVFFLLAN
                     SGMSTASLGENALANGVTVFGGFLFEVIATFLFVLVIMTVTSESKGNGPIAGLVIGLS
                     LMAMILVGLKITGLSVNPARSLAPAVLVGGAALQQVWIFILAPIAGGVLAALVAKNFL
                     GTEE"
     gene            complement(18648..18905)
                     /locus_tag="VYO11_000358"
     CDS             complement(18648..18905)
                     /locus_tag="VYO11_000358"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1594969.1"
                     /translation="MFEVVDRTDEVSLKHYFEVADRTDEVSSKHCFEVADRTDKVSSK
                     HCFEVADRTDKVSNHTYGKVKLTWFEEIFEEYHTKKPCSSR"
     gene            complement(18967..19500)
                     /gene="queF"
                     /locus_tag="VYO11_000359"
     CDS             complement(18967..19500)
                     /gene="queF"
                     /locus_tag="VYO11_000359"
                     /EC_number="1.7.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent 7-cyano-7-deazaguanine reductase
                     QueF"
                     /protein_id="HEV1594970.1"
                     /translation="MKRQSALVVFSGGQDSTTCLFWAMQHYETVEAVTFAYGQRHHLE
                     IQITREIAKEQGIRHHILDMSLLGQITAQPDFATIHISYIPDKLCVESKSLKLYLFSY
                     RNHGDFHENCINTIGKDLVNLLDPRYLEVWGKFTPRGGISIAPYYNYGKQGTKYEGLA
                     EQRLFQHDLYPEKIDNR"
     gene            complement(19804..20118)
                     /gene="trxA"
                     /locus_tag="VYO11_000360"
     CDS             complement(19804..20118)
                     /gene="trxA"
                     /locus_tag="VYO11_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003004519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HEV1594971.1"
                     /translation="MAKAITDATFEQETKDGLVLVDFWATWCGPCRMQSPILDKLSEE
                     LSEDVLKIVKMDVDENPNTARAFGIMSIPTLLFKKDGQVVKQVAGVHTAEQIKAIIAE
                     LS"
     gene            complement(20135..20356)
                     /locus_tag="VYO11_000361"
     CDS             complement(20135..20356)
                     /locus_tag="VYO11_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HEV1594972.1"
                     /translation="MIEITYIDASKNERTVTFESYEDFERSQQACLIGVADYYPVQKL
                     TYKGHNLDYHGTYGDIFFYLMKQDLSQYN"
     gene            complement(20455..20835)
                     /locus_tag="VYO11_000362"
     CDS             complement(20455..20835)
                     /locus_tag="VYO11_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEV1594973.1"
                     /translation="MTYLEKWFDFNRRQKEIESLLEETIAQQSEQSLTLKEFYLLYYL
                     DLAEEKSLRQIDLPDKLHLSPSAVSRMVARLEAKNCGLLSRMCCHQDRRSSFICLTND
                     GQKTLASLQKTVEESLEAGLDFLI"
     gene            complement(20980..21933)
                     /locus_tag="VYO11_000363"
     CDS             complement(20980..21933)
                     /locus_tag="VYO11_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000028179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HEV1594974.1"
                     /translation="MSISQRTTKLILATCLACLLAYFLNLSSAVSAGIIALLSLSDTR
                     RSTLKLARNRLFSMLLALAIGVLAFHLSGFHIWSLGLYLAFYVPLAYKMGWEIGITPS
                     TVLVSHLLVQESTSPDLLVNEFLLFAIGTGFALLVNLYMPSREEEIQHYHTLVEEKLK
                     DILQRFKYYLSRGDGRNRAQLVAELDTLLKEALRLVYLDHSDHLFHQTDYHIHYFEMR
                     QRQSRILRNMAQQINTCHLAASESLILAQLFSKIAGQLSQTNPASDLLDEIERYLEVF
                     RNRSLPKTREEFETRATLLQLLREAKTFIQVKVDFYQKYRQ"
     gene            complement(22001..23215)
                     /gene="sstT"
                     /locus_tag="VYO11_000364"
                     /pseudo
     CDS             complement(22001..23215)
                     /gene="sstT"
                     /locus_tag="VYO11_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000713440.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
     gene            23354..23914
                     /locus_tag="VYO11_000365"
     CDS             23354..23914
                     /locus_tag="VYO11_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel"
                     /protein_id="HEV1594975.1"
                     /translation="MQKFIQAYIEKLDVTTIIENILTKVISLLLLLIVFYIAKKMLHT
                     MVQRIVKPSLKMSRHDVGRQKTISRLLENVFNYTLYFFLLYCILSILGLPVSSLLAGA
                     GIAGVAIGMGAQGFLSDVINGFFILFERQLDVGDEVVLTNGPITVSGKVVSVGIRTTQ
                     LRSEEQALHFVPNRNITVVSNFSRTD"
     gene            23971..24879
                     /locus_tag="VYO11_000366"
     CDS             23971..24879
                     /locus_tag="VYO11_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HEV1594976.1"
                     /translation="MVLEKQLGNGCTWIDLDLGKLNKLEDLSEIYGLDKETIEYALDR
                     NERAHMDYHRESGTVTFIYNVLDVKKDKAYYETFPMTFIVEHRRLITISNTKNAYVIE
                     QMTRYLESHDTLSIYKFLFASLEIISNAYYPVIEQMDKSRDEVNDLLRQRTTKKNLFA
                     LSDLETGMVYLTAAAKQNRILLEHIQGHALYRSFDEIEREQFDDAMIEAHQLVSMTDL
                     ISQILQQLSASYNNILNNNLNDNLTTLTIISVLLAVLAVVTGFFGMNVPLPLTDEPHA
                     WLYISLASAGLWIVLSLLLRKIAKKS"
     gene            24831..25421
                     /locus_tag="VYO11_000367"
     CDS             24831..25421
                     /locus_tag="VYO11_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HEV1594977.1"
                     /translation="MDCFILVTKENCEKKLRKGARMAIENYIPDFAVEAVYDLTVPSL
                     QAQGIKAVLVDLDNTLIAWNNPDGTPEMKQWLHDLRDAGIGIIVVSNNTKKRVQRAVE
                     KFGIDYVYWALKPFTFGIDRAMKEFHYDKKEVVMVGDQLMTDIRAAHRAGIRSILVKP
                     LVQHDSIKTQINRTRERRVMRKITEKYGPITYKKGI"
     gene            25424..26530
                     /gene="yqeH"
                     /locus_tag="VYO11_000368"
     CDS             25424..26530
                     /gene="yqeH"
                     /locus_tag="VYO11_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000391231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HEV1594978.1"
                     /translation="MEEILCIGCGATIQTTDKAGLGFTPQSALEKGLETGEVYCQRCF
                     RLRHYNEITDVQLTNDDFLKLLHEVGDSDALVVNVIDIFDFNGSVIPGLPRFVSGNDV
                     LLVGNKKDILPKSVKSGKISQWLMKRAHEEGLRPVDVVLTSAQNKHAIKEVIDKIEHY
                     RKGRDVYVVGVTNVGKSTLINAIIQEITGDQNVITTSRFPGTTLDKIEIPLDDGSYIY
                     DTPGIIHRHQMAHYLTAKNLKYVSPKKEIKPKTYQLNPEQTLFLGGLGRFDFIAGEKQ
                     GFTAFFDNELKLHRSKLEGASAFYDKHLGTLLTPPNSKEKEDFPRLVQHVFTIKDKTD
                     LVISGLGWICVTGIAKVAVWAPEGVAVVTRKAII"
     gene            26744..27055
                     /gene="yhbY"
                     /locus_tag="VYO11_000369"
     CDS             26744..27055
                     /gene="yhbY"
                     /locus_tag="VYO11_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HEV1594979.1"
                     /translation="MSLTSKQRAFLNSQAHTLKPIIQIGKNGLNDQIKTSVRQALDAR
                     ELIKVTLLQNTDENIHEVAEILEEEIGVDTVQKIGRILILFKQSSKKENRKISKKVKE
                     I"
     gene            27107..27736
                     /locus_tag="VYO11_000370"
     CDS             27107..27736
                     /locus_tag="VYO11_000370"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HEV1594980.1"
                     /translation="MTIELLTPFTKVELEPEIKEKKRKQVGILGGNFNPVHNAHLIVA
                     DQVRQQLGLDQVLLMPEYQPPHVDKKETIPEHHRLKMLELAIEGIDGLVIETIELERK
                     GISYTYDTMKILTEKNPDTDYYFIIGADMVDYLPKWYRIDELVDMVQFVGVQRPRYKA
                     GTSYPVIWVDVPLMDISSSMVRAFLAQGRKPNFLLPQPVLDYIEKEGLY"
     gene            27736..28329
                     /gene="yqeK"
                     /locus_tag="VYO11_000371"
     CDS             27736..28329
                     /gene="yqeK"
                     /locus_tag="VYO11_000371"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HEV1594981.1"
                     /translation="MSYQDYINCSREALLEKMAELLPEKRLTHCLGVERAAMELAQRF
                     GVDVEKASLAGLLHDYAKKLSDQEFLDLIDRYQLDPDLKNWGNNVWHGMVGIYKIQED
                     LDLHDSEILRAIEVHTVGAGQMTDLDKVIYVADYIEHNRAFPGVDVAREIASLSLNKA
                     VAYETARTVEYLAHQGFPIYPQTLETYNAFVHYLKEN"
     gene            28330..28830
                     /locus_tag="VYO11_000372"
     CDS             28330..28830
                     /locus_tag="VYO11_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HEV1594982.1"
                     /translation="MKTAFIIIDVQNVLVETGFQTKSLLGKISYLQNQARSKNIEIIY
                     VQHIENSEAQTSEDWQLSALLNRKPAEKVFQKKYNSIFKETGLKEYLDKQGIEKLVLC
                     GMQTEYCVDTSVKVAFEYGYQLIVPEGAVTTFDGDDIPAETINEFYEDIWEERFADVL
                     DYKHIF"
     gene            28843..29196
                     /gene="rsfS"
                     /locus_tag="VYO11_000373"
     CDS             28843..29196
                     /gene="rsfS"
                     /locus_tag="VYO11_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HEV1594983.1"
                     /translation="MNEKELLELVVKAADEKRAEDILALDVQDLTSVTDYFVITSSMN
                     SRQLDAIAANIREKVAQAGFKGSHVEGDAAGGWVLLDLGAVVVHIFSEEMRAHYNLEK
                     LWHEANSVDISEALA"
     gene            29299..30045
                     /locus_tag="VYO11_000374"
     CDS             29299..30045
                     /locus_tag="VYO11_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000605145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEV1594984.1"
                     /translation="MIMATYETFAAVYDAVMDDSLYDKWTNFSLRHLPKTKEKKKLLE
                     LACGTGIQSVRFSQAGFDVTGLDLSADMLKIAEKRATSAKQKIAFIEGNMLNLSKAGK
                     YDFVTCYSDSICYMQDEVEVGDVFKDVYNALNEEGVFIFDVHSTYQTDEVFPGYSYHE
                     NAEDFSMLWDTYEDEVPHSIVHELTFFIKEADGSFSRHDEVHEERTYEILTYDILLEQ
                     AGFKSFKLYADFEDKEPTETSTRWFFVAQK"
     gene            30055..31152
                     /locus_tag="VYO11_000375"
     CDS             30055..31152
                     /locus_tag="VYO11_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000156376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HEV1594985.1"
                     /translation="MTITGIIAEFNPFHNGHKYLLDQAEGLKIVAMSGNFMQRGEPAI
                     VDKWTRAQMALENGADLVVELPFLVSVQAADFFGQGAVDILDRLGIDSLVFGTEEVRD
                     YQKIADLYTEKGAEMEKFVENLPDSLSYPQKTQAMWKEFAGLDFSGNTPNHVLALAYA
                     KAVAGRNIKLHPIQRQGAGYHSVNKDVDFASATALRQHQKDQDFLERFMPSVALFEQA
                     SKVIWEDYFPLLRYQILSNPDLTTIYQVNQEMAVRIKEAIKTAQSVEELVELVTTKRY
                     TKARVRRLLTYILMQARESDLPEAIHVLGFTEKGRQHLKSLKGQVSLVSRIGKEPWDA
                     MTQKVDQIYQLGKPSIAEQNFGRVPIRIETN"
     gene            31390..31620
                     /locus_tag="VYO11_000376"
     CDS             31390..31620
                     /locus_tag="VYO11_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HEV1594986.1"
                     /translation="MEAVLYSTFRNHLKDYMKKVNDEFEPLTVVNKNPDEDIVVLSKS
                     EWDSIQETLRIAQNKELSDKVLRGMDKIRAGH"
     gene            31889..33502
                     /locus_tag="VYO11_000377"
     CDS             31889..33502
                     /locus_tag="VYO11_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HEV1594987.1"
                     /translation="MEFMSLAIAVFAVIIGLVIGYVSISAKMKSSQEAAELMLLNAEQ
                     EATNLRGQAEREADLLVNEAKRESKSLKKEALLEAKEEARKYREEVDAEFKSERQELK
                     QIESRLTERATSLDRKDDNLTSKEQTLEQKEQSISDRAKNLDAREEQLEEVERQKEAE
                     LERIGALSQAEARDIILAQTEENLTREIASRIREAEQEVKERSDKMAKDILVQAMQRI
                     AGEYVAESTNSTVHLPDDTMKGRIIGREGRNIRTFESLTGVDVIIDDTPEVVTLSGFD
                     PIRREIARMTMEMLLKDGRIHPARIEELVEKNRQEIDNKIREYGEAAAYEIGAPNLHP
                     DLMKIMGRLQFRTSYGQNVLRHSIEVAKLAGIMASELGENAALARRAGFLHDIGKAID
                     HEVEGSHVEIGMELARKYKEPPVVVNTIASHHGDVEAESVIAVIVAAADALSAARPGA
                     RSESLESYIKRLHDLEEIANGFEGVQTSFALQAGREIRIMVNPGKIKDDKVTILAHKV
                     RKKIENNLDYPGNIKVTVIRELRAVDYAK"
     gene            33632..34258
                     /gene="gmk"
                     /locus_tag="VYO11_000378"
     CDS             33632..34258
                     /gene="gmk"
                     /locus_tag="VYO11_000378"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HEV1594988.1"
                     /translation="MADRGLLIVFSGPSGVGKGTVRREIFESSENQFQYSVSMTTRAQ
                     RPGEVDGVDYFFRTREEFEELIRQGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVFLE
                     IEVQGALQVKKKVPDAVFIFLTPPDLDELQDRLVGRGTDSAEVIAQRIEKAKEEIALM
                     REYDYAIVNDQVPLAAERVKCVIEAEHFCVDRVIGHYQEMLPKSPTTR"
     gene            34283..34597
                     /locus_tag="VYO11_000379"
     CDS             34283..34597
                     /locus_tag="VYO11_000379"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HEV1594989.1"
                     /translation="MMLKPSIDTLLDKVPSKYSLVILEAKRAHELEAGAPATQGFKSE
                     KSTLRALEEIESGNVTIHPDPEGKREAVRRRIEEEKRRKEEEEKKIKEQIAKEKEDGE
                     KI"
     gene            34663..37059
                     /locus_tag="VYO11_000380"
     CDS             34663..37059
                     /locus_tag="VYO11_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001162119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HEV1594990.1"
                     /translation="MALAKIIVDVPLMQTDQPYSYRIPEEFEGMLEVGMRVHVPFGKG
                     NRLIQGIVLGLESQSDGEEMEQDLKDIAEVLDFSPVLTPEQLWLAEELRKSVFSYKIS
                     ILKAMLPGFLNSSYDKILYPLEGLSQEERVRLFGSEDSLAFSSLDLAKQAEMMRLTRK
                     GLLGLEYQAVDQKKVKTQSWYEVDHAQLEGVEISTRAKKKLELRDYLLSHPESASLAS
                     LLESYSREQVNFFVDQGAVTIVQKEVQRSAAYFEGIEASRPLELNPEQRQARDAVVSS
                     IGSSQPPFLLQGITGSGKTEVYLQIIQGALDKGKTAILLVPEISLTPQMTERFIARFG
                     DKVAILHSGLSNGEKYDEWRKVERGDAQVVVGARSAIFAPLKNLGVMIIDEEHEAAYK
                     QDSNPRYHAREVAILRAQYNQATLVLGSATPSLESRARAGKGVYQHLRLTQRANPLAT
                     IPEVQVIDFRDYIGQNETSNFTPPLLEAIQDRLVKKEQVVLMLNRRGYSSFVMCRECG
                     TVDTCPNCDISLTLHMDTKTMNCHYCGFSKDIPQVCPNCKSHSIRYYGTGTQKAYDEL
                     AELFPQARILRMDVDTTRKKGSHQALLDQFGRGKADILLGTQMIAKGLDFPNVTLVGV
                     LNADTALNLPDFRSSERTFQLLTQVAGRAGRAEKAGQVLIQSYNSQHYAIRFAKDQDY
                     EGFYAYEMGIRRQLGYPPYYFTIGITLSHKKEEEVFKRAYEVMNILRSGLSETSPILG
                     PTPKPIARTHNLYHYQILIKYRLEDELGPTLNQVLALTQERENSELRLSIDHEPQQFL
                     "
     gene            37072..38007
                     /locus_tag="VYO11_000381"
     CDS             37072..38007
                     /locus_tag="VYO11_000381"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HEV1594991.1"
                     /translation="MTKLIFMGTPDFSATVLKGLLTDDRYEILAVVTQPDRAVGRKKV
                     IQETPVKQAAKEAGLSIYQPEKLSGSPEMEDLMKLGADGIVTAAFGQFLPSKLLDSMD
                     FAVNVHASLLPRHRGGAPIHYALIQGDEEAGVTIMEMVKEMDAGDMISRRSIPITDED
                     NVGTLFEKLALVGRDLLLDTLPAYIAGDIKPEPQDTSQVTFSPNIKPEEEKLDWNKTN
                     RQLFNQIRGMNPWPVAHTFLKGDRFKIYEALPVEGQGNPGEILSIGKKELIVATAEGA
                     LSLKQVQPAGKPRMDIASFLNGVGRTLTVGERFGD"
     gene            38000..39313
                     /gene="rsmB"
                     /locus_tag="VYO11_000382"
     CDS             38000..39313
                     /gene="rsmB"
                     /locus_tag="VYO11_000382"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HEV1594992.1"
                     /translation="MTKVETARSLALAVLEDVFVNQAYSNIALNKHLKGSQLLAADKG
                     LVTELVYGTVARKLTLEWYLSHFIEDRDQLDSWLYVLLLMSAYQLRYLDKIPDHAVVN
                     EAVELAKLRKKGSEKLVNALLRRILREGWPDISSIKRKNKRDSIAYSLPVWLVAKLKE
                     EYGEERAKAIFESLLVRNKASIRVTDLSRKEEIQALLEANNSLLATTGLVKEQGHFAG
                     HNLFADGAITIQDESSQLVAPTLDLQGDERVLDACAAPGGKTAHIASYLTTGQVTALD
                     LYDHKLDLIQENAQRLGVADRVQTQKLDARKVHEFFDQDSFDKILVDAPCSGIGLLRR
                     KPDIKYNKETADFASLQEIQLEILGSVCQILGKGGIITYSTCTIVSEENFQVVKAFLE
                     SHPEFEQVKLEHECKDIMKDGCILITPELYGSDGFFISQFRKISD"
     gene            39328..40068
                     /locus_tag="VYO11_000383"
     CDS             39328..40068
                     /locus_tag="VYO11_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HEV1594993.1"
                     /translation="MEISLLTDVGQKRTNNQDYVNHYVNRAGRTMIILADGMGGHRAG
                     NIASEMAVTDLGVAWVDTQIDTVNEVREWFAHYLEIENQKIHQLGQDEAYRGMGTTLE
                     VLAIIDNQAIYAHIGDSRIGLIRGEEYHQLTSDHSLVNELLKAGQLTPEEAEAHPQKN
                     IITQSIGQKDEIQPDFGTVILESGDYLLLNSDGLTNMISGSEIRDIITSDIPLADKTE
                     TLVRFANNAGGLDNITVALVSMNEEDEE"
     gene            40065..42044
                     /gene="pknB"
                     /locus_tag="VYO11_000384"
     CDS             40065..42044
                     /gene="pknB"
                     /locus_tag="VYO11_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HEV1594994.1"
                     /translation="MIQIGKIFAGRYRIVKQIGRGGMADVYLAKDLILDGEEVAVKVL
                     RTNYQTDPIAVARFQREARAMADLDHPHIVRITDIGEEDGQQYLAMEYVAGLDLKRYI
                     KEHYPLSNEEAVRIMGQILLAMRLAHTRGIVHRDLKPQNILLTPDGTAKVTDFGIAVA
                     FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAV
                     TIALQHFQKPLPSVIAENPSVPQALENVIIKATAKKLTNRYRSVSEMYVDLSSSLSYN
                     RRNESKLIFDETSKADTKTLPKVSQSTLTSIPKVQAQTEHKSIKNPSQAVTEETYQPQ
                     APKKHRFKMRYLILLASLVLVAASLIWILSRTPATIAIPDVAGQTVAEAKATLKKANF
                     EIGEEKTEASEKVEEGRIIRTDPGAGTGRKEGTKINLVVSSGKQSFQISNYVGRKSSD
                     VIAELKEKKVPDNLIKIEEEESNESEAGTVLKQSLPEGTTYDLSKATQIVLTVAKKAT
                     TIQLGNYIGRNSTEVISELKQKKVPENLIKIEEEESSESEPGTIMKQSPGAGTTYDVS
                     KPTQIVLTVAKKVTSVAMPSYIGSSLEFTKNNLIQIVGIKEANIEVVEVTTAPAGSVE
                     GMVVEQSPRAGEKVDLNKTRVKISIYKPKTTSATP"
     gene            42159..42917
                     /locus_tag="VYO11_000385"
     CDS             42159..42917
                     /locus_tag="VYO11_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HEV1594995.1"
                     /translation="MEESKELNAVIDVIMLAGTILLKSGSEIHRVEDTMIRIAHSQGI
                     VDCNVLAMPAAIFFSIENTNISRMKRVTSSSYNIEKVCDVNQISRQLVGGQIDLETAF
                     KQLTALQAQPLPYTKLQVTLAATFSAPFFSVMFSGNIYDALGAGVATLFGFAFSLYVE
                     KFIRIPFVTAFAGAFVFGIIAQFWARYTGFPSTADLIIAGAVMPFVPGIALTNAVRDI
                     MTNHINSGMSKMFESLLITLALGAGTSVALVLMN"
     gene            42919..43368
                     /locus_tag="VYO11_000386"
     CDS             42919..43368
                     /locus_tag="VYO11_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HEV1594996.1"
                     /translation="MTLTTFLLQAVASFLAIITFLIVLNVQRSMLLPGGILGMTVWLI
                     YLLLKEPTNVIVATFIAAIIGSCVSQILSILYKTPAVVFILAILAPLVPGYLSYRTTA
                     FFVTGDYNKALASATLVVMLALVISIGMASGTVILRLYHYIKTHRVS"
     gene            43430..44056
                     /locus_tag="VYO11_000387"
                     /pseudo
     CDS             43430..44056
                     /locus_tag="VYO11_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
     gene            44124..44372
                     /locus_tag="VYO11_000388"
     CDS             44124..44372
                     /locus_tag="VYO11_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1594997.1"
                     /translation="MVSSSGSEFQSGWQEHQLIAEKVSKTLDKTFDKDVREIPTSQFY
                     QKFVDEMGRTYSGNLILQELITVNGAYKATYIGELSSN"
     gene            44503..45675
                     /locus_tag="VYO11_000389"
     CDS             44503..45675
                     /locus_tag="VYO11_000389"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004181031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HEV1594998.1"
                     /translation="MTIGIDKIGFATSQYVLKLQDLAEARGIDPEKLSKGLLLKELSI
                     APLTEDIVTLAASASDSILTEQERQEVDMVIVATESGIDQSKAAAVFVHGLLGIQPFA
                     RSFEIKEACYGATAALHYAKLHVENSPESKVLVIASDIAKYGIETPGEPTQGAGSVAM
                     LITQNPRMMAFNNDNVAQTRDIMDFWRPNYSTTPYVNGVYSTQQYLDSLKTTWLEYQK
                     RYQLTLDDFAAVCFHLPYPKLALKGLKKIMDKSLPQEKKDLLQKHFDQSILYSQKVGN
                     IYTGSLFLGLLSLLENTDSLKAGDKIALYSYGSGAVAEFFSGELVEGYEAYLDKDRLN
                     KLNQRTALSVADYEKVFFEEVNLDETNSAQFAGYENQDFALVEILDHQRRYSKVEK"
     gene            45675..46949
                     /locus_tag="VYO11_000390"
     CDS             45675..46949
                     /locus_tag="VYO11_000390"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000704367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HEV1594999.1"
                     /translation="MKISWNGFSKKSYQERLELLKAQALLSPERQASLEKDEQMSVTV
                     ADQLSENVVGTFSLPYSLVPEVLVNGQEYTVPYVTEEPSVVAAASYASKIIKRAGGFT
                     AQVHQRQMIGQVALYQVANPKLAQEKIASKKAELLELANQAYPSIVKRGGGASDLHVE
                     QIKGEPDFLVVYIHVDTQEAMGANMLNTMLEALKPVLEELSQGQSLMGILSNYATDSL
                     VTASCRMAFRYLSRQKDQGREIAEKIALASQFAQADPYRAATHNKGIFNGIDAILIAT
                     GNDWRAIEAGAHAFASRDGRYQGLSCWTLDLEREELVGEMTLPMPVATKGGSIGLNPR
                     VALSHDLLGNPSARELAQIIVSIGLAQNFAALKALVSTGIQQGHMKLQAKSLALLAGA
                     SESEVAPLVERLISDKTFNLETAQRYLENLRS"
     gene            complement(46984..47949)
                     /locus_tag="VYO11_000391"
     CDS             complement(46984..47949)
                     /locus_tag="VYO11_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002929307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV1595000.1"
                     /translation="MVAKLTDVAKLAGVSPTTVSRVINKKGYLSEKTIQKVNEAMREL
                     GYKPNNLARSLQGKSAKLIGLIFPNISNVFYAELIDKLEHQLFKNGYKTIICNSEHDS
                     EKEREYIEMLEANQVDGIISGSHNLGIEDYNRVTAPIISFDRNLSPDIPVVSSDNYAG
                     GVLAAQTLVKTGAQSIIMITGNDNSNSPTGLRHAGFASVLPKAPIINVSSDFSPVRKE
                     MEIKNILTREKPDAIFASDDLTAILVIKIAQELGISVPKELKVIGYDGTYFIENYYPQ
                     LATIKQPLEEIACLTIDLLLQKIEGKEVATTGYFLPVTLLPGKSI"
     gene            complement(47930..49384)
                     /locus_tag="VYO11_000392"
     CDS             complement(47930..49384)
                     /locus_tag="VYO11_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HEV1595001.1"
                     /translation="MEWTTERRYRLYQDWTQEEIQHIKENMAQSPWHTHYHVEPKTGL
                     LNDPNGFSYFDGKWILFYQNFPFGAAHGLKSWAQLESDDLVHFKETGIKVLPDTPLDS
                     HGAYSGSAMKFGDNLFLFYTGNVRDENWIRHPYQIGALMDKEGKITKIDKILIDQPAD
                     STDHFRDPQIFNFKGQYYAVVGGQDLEKKGFVRLYKAINNDYTNWQAVGDLDFANDRT
                     AYMMECPNLVFVEEQPVLLYCPQGLDKKVLDYDNIFPNMYKIGASFDPKNAKMVDVSQ
                     LQNMDYGFEAYATQAFNAPDGRVLAVSWLGLPDVSYPSDRFDHQGTFSLVKELTIKDD
                     KLYQYPVAAIKDLRASEEAFSNRSQTKNTYELELNLEANSQSEIVLLADKEGKGLSIN
                     FDLVNSQVTVDRSQAGEQYAQEFGTTRSCPIENQATTATIFIDNSVFEIFINKGEKVF
                     SGRVFPHADQNGILIKSGNPTGTYYELDYGRKTN"
     gene            49761..51644
                     /locus_tag="VYO11_000393"
     CDS             49761..51644
                     /locus_tag="VYO11_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEV1595002.1"
                     /translation="MNNQEIAKKVIDALGGRENVNSVAHCATRLRVMVKDEEKINKEV
                     IENLEKVQGAFFNSGQYQIIFGTGTVNKMYDEVVVLGLPTSSKDDMKAEVAKQGNWFQ
                     RAIRTFGDVFVPIIPVIVATGLFMGVRGLFNALEMPLPGDFATYTQILTDTAFIILPG
                     LVVWSTFRVFGGNPAVGIVLGMMLVSGSLPNAWAVAQGGEVTAMNFFGFIPVVGLQGS
                     VLPAFIIGVVGAKFEKAVRKVVPDVIDLLVTPFVTLLVMSILGLFVIGPVFHVVENYI
                     LIATKAILSMPFGLGGFLIGGVHQLIVVSGVHHIFNLLEVQLLAADHANPFNAIITAA
                     MTAQGAATVAVGVKTKNPKLKTLAFPAALSAFLGITEPAIFGVNLRFRKPFFLSLIAG
                     AIGGGLASILGLAGTGNGITIIPGTMLYVGNGQLPQYLLMVAVSFALGFALTYMFGYE
                     DEVDATAAAKQAEVAEEKEEVAPAALQNETLVTPIVGDVVALADVNDPVFSSGAMGQG
                     IAVKPSQGVVYAPADAEVSIAFPTGHAFGLKTRNGAEVLIHVGIDTVSMNGDGFEAKV
                     SQGNKVKAGDVLGTFDSNKIAAAGLDDTTMVIVTNTADYASVAPVATGSVAKGDAVIE
                     VKI"
     gene            51793..52680
                     /locus_tag="VYO11_000394"
     CDS             51793..52680
                     /locus_tag="VYO11_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000164317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEV1595003.1"
                     /translation="MTKLYGSLEAGGTKFVCAVGDENFNVVEKTQFPTTTPIETIDKT
                     IEFFSKFDNLAGLAVGSFGPIDIDKNSKTYGFITTTPKPNWANVDLLGALRRALNVPM
                     YFTTDVNSSAYGEMVARNNAGGRIENLVYYTIGTGIGAGVIQRGEFIGGVGHPEMGHY
                     YVARHPMDIEKEFKGVCPFHKGCLEGYAAGPSLEARTGVRGETIELNNPVWDVQAYYI
                     AQAAVNATVTFRPDVIVFGGGVMAQQHMLDRVREKFTSLLNGYLPVPDVRDYIVTPAV
                     AGNGSATLGNFVLAKEVSK"
     gene            complement(53000..53617)
                     /locus_tag="VYO11_000395"
     CDS             complement(53000..53617)
                     /locus_tag="VYO11_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HEV1595004.1"
                     /translation="MSQDKQMKAVSPLLQRVINISSIVGGVGSLIFCIWAYQAGILQS
                     KETLSAFIQQAGIWGPPLFIFLQILQTVVPIIPGALTSVAGVFIYGHIIGTIYNYIGI
                     VIGCAIIFYLVRLYGAAFVQSVVSKRTYDKYIGWLDKGNRFDRFFIFMMIWPISPADF
                     LCMLAALTKMSFKRYMTIIILTKPFTLVVYTYGLTYIIDFFWQML"
     gene            complement(54032..54220)
                     /locus_tag="VYO11_000396"
                     /pseudo
     CDS             complement(54032..54220)
                     /locus_tag="VYO11_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153868.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(54730..54810)
                     /locus_tag="VYO11_000397"
                     /pseudo
     CDS             complement(54730..54810)
                     /locus_tag="VYO11_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            54927..55820
                     /locus_tag="VYO11_000398"
     CDS             54927..55820
                     /locus_tag="VYO11_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1595005.1"
                     /translation="MLEVRSLEKSFGSKQVLFGIDFQARPGRILGLVGKNGAGKTTIF
                     HSILKFLEYQGEIGLDGQDIRQETYARIGYLPEERSLMPKLTVLEQVRYLATLKGMDA
                     KEVKEKLPQWMKRLEVKGKLTDKIKSLSKGNQQKIQLIITLIHEPDLIILDEPFSGLD
                     PVNTELLKQVIFQEKERGATIIFSDHVMTNVEELCDDILMIRDGRVVLHGPVQDVRNQ
                     YGKTRLFVSSERSKEELENLPHVKQVSLTKQGSWKLILEDESAGRELFPILTQGQYIA
                     TFDQQAPTIDEIFKLESGVEV"
     gene            55817..57016
                     /locus_tag="VYO11_000399"
     CDS             55817..57016
                     /locus_tag="VYO11_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1595006.1"
                     /translation="MRNMWVVIKETYLRHVESWSFFFMVISPFLFLGISVGIGHLQGS
                     SMAKNNKVAVVTTVPSVAEGLKNVNGVNFDYKDEASAKEAIKEEKLKGYLTIDQEDSV
                     LKAVYHGETSLENGIKFEVTGILNELQNQLNRSTASLSQEQEKRLAQTIQFTEKIDEV
                     KENKKFIQTIAAGALGFFLYMILITYAGVTAQEVASEKGTKIMEVVFSSIRASHYFYA
                     RMMALFLVILTHIGIYVVGGLAAVLLFKDLPFLAQSGILVHLGDAISLNTLLFILISL
                     FMYVVLAAFLGSMVSRPEDSGKALSPLMILIMGGFFGVTALGAAGDNLLLKIGSYIPF
                     ISTFFMPFRTINDYAGGAEAWISLAITVIFAVVATGFIGRMYASLVLQTDDLGIWKTF
                     KRALSYK"
     gene            complement(57369..58136)
                     /locus_tag="VYO11_000400"
     CDS             complement(57369..58136)
                     /locus_tag="VYO11_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000498762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1595007.1"
                     /translation="MFWNLVRYEFKNVNKWYLALYAAVLVLSALIGIQTQGFKNLPYQ
                     ESQATMLLFLATVFGGLMLTLAISTIFLIIKRFKGSVYDRQGYLTLTLPVSEHHIITA
                     KLIGAFIWSLISTAVLALSAVIILALTAPEWIPLSYVITFVETHLPQIFLTGISFLLN
                     TISGILCIYLAISIGQLFNEYRTALAVAAYIGIQIVIGFIELFFNLSSNFYVNSLVGL
                     NDHFYMGAGIAIVKELIFIAIFYLGTYYILRNKVNLL"
     gene            complement(58153..58848)
                     /locus_tag="VYO11_000401"
     CDS             complement(58153..58848)
                     /locus_tag="VYO11_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1595008.1"
                     /translation="MSLLVFENVSKSYGATPALENVSLDIPAGKIVGLLGPNGSGKTT
                     LIKLINGLLQPDQGRVLINDMDPSPATKAVVAYLPDTTYLNEQMKVKEALTYFKTFYK
                     DFNLERAHHLLADLGIDENSRLKKLSKGNKEKVQLILVMSRDARLYVLDEPIGGVDPA
                     ARAYILNTIINNYSPTSTVLISTHLISDIEPILDEIVFLKDGKVVRQGNVDDIRYESG
                     ESIDQLFRQEFKA"
     gene            complement(58853..59218)
                     /locus_tag="VYO11_000402"
     CDS             complement(58853..59218)
                     /locus_tag="VYO11_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEV1595009.1"
                     /translation="MSWTFDNKKPIYLQIMEKIKLQIVSHTLEPNQQLPTVRELASEA
                     GVNPNTIQRALSDLEREGFVYSKRTTGRFVTKDKELIAQSRKQLSEEELEHFVSSMTH
                     FGYEKEELPGVVSDYIKGV"
     gene            59358..59831
                     /gene="nrdR"
                     /locus_tag="VYO11_000403"
     CDS             59358..59831
                     /gene="nrdR"
                     /locus_tag="VYO11_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001203675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HEV1595010.1"
                     /translation="MRCPKCGATKSSVIDSRQAEEGNTIRRRRECDECQHRFTTYERV
                     EERTLVVVKKDGTREQFSRDKIFNGIIRSAQKRPVSSDEINMVVNRIEQKLRGRNENE
                     IQSEDIGSLVMEELAELDEITYVRFASVYRSFKDVSELESLLQQITQSSKKKKER"
     gene            59832..61001
                     /locus_tag="VYO11_000404"
     CDS             59832..61001
                     /locus_tag="VYO11_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000802368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation and membrane attachment
                     family protein"
                     /protein_id="HEV1595011.1"
                     /translation="MKPIDRFSYLQNNRVSQDTSSLVQCYLPIIGQEALSLYLYTISF
                     WDNGRKEYLFSSILNHLNFGMDRLIKSLKILSAFNLLTLYQKGDVYQLALHAPLSSQD
                     FLRHPVYRRLLEKKIGDSAVEDLKVESADGEEIPVSLNQVFPELAELGSQEDLGLKKK
                     VANDFDLEHFRQLMARDGLRFADEQSDVLNLFAIAEEKKWTWFETYQLAKSTAVSQVI
                     STKRMREKIAQKPVSSDFSLKETTIIKEAKSKTALQFLAEIKQTRKGTITQTERELLQ
                     QMAGLGLLDEVINIILLLTFNKVDSANINEKYAMKVANDYAYQKIHSAEEAVLRIRER
                     GQKAKTQKQNQTAPAKTNIPKWSNPEYKNTSSAEELEEMERQTLELLAKLDNGGD"
     gene            61002..61898
                     /gene="dnaI"
                     /locus_tag="VYO11_000405"
     CDS             61002..61898
                     /gene="dnaI"
                     /locus_tag="VYO11_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HEV1595012.1"
                     /translation="MESVGDVLKRQPSRFHYQDLVQKIMKDPDVAAFVQQESLNQDEL
                     NRSISKFNQYITERDKFLRGDTDYIAKGYKPILVMNHGYADVSYEETPELIAAEKEAA
                     IKKRLNLINFPSSLKNVSFLDVYRDDVQRLTVLKRMIEFVNDYPNNLKGLYLYGDFGV
                     GKSFMVAALAHDLSEKRGVSSTLLHYPSFVIDVKNAIGDGNVKTLVDEIKFSEVLILD
                     DIGAEQSTAWVRDEILQVILQYRMQENLPTFFTSNFNFEDLEKHFAKGKNGNDETWEA
                     RRVMERIRYLAEETRLEGVNRR"
     gene            61895..62608
                     /locus_tag="VYO11_000406"
     CDS             61895..62608
                     /locus_tag="VYO11_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent oxidoreductase"
                     /protein_id="HEV1595013.1"
                     /translation="MTETIKLMKAHTSVRRFKEQEIPQVDLNEILTAAQMASSWKNFQ
                     SYSVIVVRSQEKKDALYELVPQEAIRQSAVFLLFVGDLNRAEKGARLHTDTFQPQGVE
                     GLLISSVDAALAGQNALLAAESLGYGGVIIGLVRYKSEEVAELFNLPDYTYSVFGMAL
                     GVPNQHHDVKPRLPLENVVFEEEYQEQSTETIQAYDRVQADYAGGRATTSWSQRLAEQ
                     FGQAEPSSTRKNLEQKKLL"
     gene            62622..63932
                     /gene="der"
                     /locus_tag="VYO11_000407"
     CDS             62622..63932
                     /gene="der"
                     /locus_tag="VYO11_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HEV1595014.1"
                     /translation="MALPTIAIVGRPNVGKSTLFNRIAGERISIVEDVEGVTRDRIYA
                     TGEWLNRSFSMIDTGGIDDVDAPFMEQIKHQAEIAMEEADVIVFVVSGKEGITDADEY
                     VARKLYKTHKPVILAVNKVDNPEMRNDIYDFYALGLGEPLPISSVHGIGTGDVLDAIV
                     ENLPNEYEEENPDVIKFSLIGRPNVGKSSLINAILGEDRVIASPVAGTTRDAIDTHFT
                     DTDGQEFTMIDTAGMRKSGKVYENTEKYSVMRAMRAIDRSDVVLMVINAEEGIREYDK
                     RIAGFAHEAGKGMIIVVNKWDTLEKDNHTMKNWEEDIREQFQYLPYAPIIFVSALTKQ
                     RLHKLPGMIKQISESQNTRIPSAVLNDVIMDAIAINPTPTDKGKRLKIFYATQVATKP
                     PTFVIFVNEEELMHFSYLRFLENQIRKAFVFEGTPIHLIARKRK"
     gene            64023..64358
                     /locus_tag="VYO11_000408"
     CDS             64023..64358
                     /locus_tag="VYO11_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1595015.1"
                     /translation="MEHLFKFLLLAPYFYFDNWIEKANRNSKFFPIFYYFYWIYIPFY
                     SLFSLAWTVVSVLFFNTVLRNVTDIKLWGIWFLFILLAIGMNWLTYSCFKEMFRLRQE
                     LGKSKGGRH"
     gene            64498..64848
                     /locus_tag="VYO11_000409"
     CDS             64498..64848
                     /locus_tag="VYO11_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1595016.1"
                     /translation="MEHLFKMIILLPCFYFFSWIDKDNRESKFFPIFYYFYWIYITLY
                     ALFSLAWTVFSVLFFNIVLRNLTDIKLWGIWLLLLLIAFASDWLDYICFKKMLDLRRE
                     LGKSKGVHKGRCRN"
BASE COUNT        19373 a        12081 c        14619 g        18941 t
ORIGIN      
        1 aggatgttaa aaaaaactat ttacaattag ttactactgc cacttctgat aatatgtctg
       61 ttattgagtt tgagatggaa aaagaatccg atttgtatta ttttattaaa gcaacattag
      121 gttcttcttt tagtcgtatg cactattcag tattagtcaa ggctcttgct ggtgctcttg
      181 caaaaaatat ataaatatat attataatgg ggagaccctc cccatttata tatttaaaca
      241 aaggagaaaa aatatgttta agaatttttg tcaaaatgct tttattagcc tatatttcat
      301 agtatcagcc ctaggaggct tctctgcgcg tctcgagttc cgttcattct ccccttatca
      361 atctatgaaa gtagccttgt tattaggagt catcttaatt ttattgcaac ttccaattat
      421 gtttgctaaa ttattagaag ctttaaaaat caagaaaggt gaaactcatg aatgacatcg
      481 taaaaatgag attagccttt tgtgttacta taatattgat ggcatgctct gtttttgtgt
      541 ttactcctgt tggagaaggc atgtccctac tttgctcaat ttttgctacc ccgtttttat
      601 ttatttttgt cttctatttt tttaaaataa aattaagaat tttacttatt attatcaagg
      661 atttcataaa aaaatttaga taggtataag atgtttaaaa ttaaacaaac ggcttcttta
      721 tctgagcatt actttttaaa tacatctaaa ttgagaagta ttcgctggtt tactatagga
      781 tttttgagca tattgtcctt ttctagtagt attcttttta agggatggtt tctccaaatg
      841 attacattat ctgttgagtt aattataatt ttgtatattg aaagaaaaat taagggatgg
      901 gctcagcaga ttgaaccgct gttaattgtc agagaaaacc ttctatttat gcttcgcaga
      961 aattcctttc tttttacagc aacaaaagat ggcgctattc ttcgttcagc taaatttaat
     1021 taccaattga atgatgtttc aattgtagtc catgcattaa aatctggtga tgaatttacg
     1081 aaagagatgg agactttaga cgttttccta tctagtactt tgggaataag cctatcgtct
     1141 aaagaaattt atgctactca tgttgaatat gtttttgtat ataaacagcc tgaacgttta
     1201 tatgttacct ccctccctct tgaagatgat agcctgaaaa ttaaaatcta tgatgatttt
     1261 gttatcgatt tgagaaaaaa cttttccatg cttatatcgg gggcctcagg tagtggaaaa
     1321 tcattcttta catattatta cttgactcgt ttcatatccc agaccgtaaa tgggaaacat
     1381 gcaaaaatat atgtgattga tccaaaattt tcagatattt ataaattatg cgaattttct
     1441 ggttttccag tagaaaatta tggaacaact aatgaggatg cctttagaat tttgcgtcag
     1501 tatatcaagg agctagatag acgtatgcta atctataatc aaagcaattt gttcaacagt
     1561 attggcatag acttgggctt tcctccttta cttttggtaa tagaagaata tagttcatta
     1621 gttagttcga tggatagtaa agctaaaaaa gattttgaaa atatggttgc tatcgttgct
     1681 caaaaagcaa ggtctctatc tatgggggtt tgtattgtta tgcaacaacc ccgttccgat
     1741 agcctttcga caaatattag agaacagctt gtcaatgcta tattccttgg agccccaact
     1801 cgggaatcta gtcagatgat gttcggcaca acagatgtgc ccaatgtcaa gaaggataaa
     1861 ggagttgggc tttgctctac ggatagagag tctcccaagg aatttcaagc cccaattttt
     1921 aacagagatg tatttgagac aatactccca gtttgggaat gtgcggctaa aaattatatg
     1981 aaggatgaag atgagaatgt atgagataga aatgtaatga aggattatga atctgatacc
     2041 aatccatata aggcgttgct aaaagcaatg aatatggctc acatgtttat cgttgacgag
     2101 ctggaataga gggattgaat attatgattt taaaacacat ctgtggtgtg tgagaatctt
     2161 aagcgttttg aagatgaata aaattttttt attcattttc aaaatgccat tgtgcagccg
     2221 gcgaacaaca aggccggttc gaacgaacgt tcgaataaat gtatttatgt ccaatactga
     2281 ttgacgttaa aagctgtata ttattttaaa taaggaagga ttttttaact atgaaagaaa
     2341 ctgttgttgt tctagctatt tctactaaga aagaacgagg ctggataaaa gtctccaccc
     2401 ttaatgattg ttggagtgac ctaggtatgc atttcgataa atccaaattt ggagctgttt
     2461 tctctgctcc aggcctttat gaggttgaag tgattaataa tgcttcattt ggacagaatg
     2521 cccaatatga ggtaattcaa tccagaaagc ttgggacctt tgcagaattg attgaacaag
     2581 tcaaaaatta aataatttat atttagggta aggctggacc tgccagcttt gctggcaagt
     2641 ggagcgtggt cagtggaacg gcagtcttgc cctaaaattt aagtatatag aatgttttgt
     2701 tttttgaagg agaaatttca tgaataaaga agttttaaat cgggctcctt ctaacagccc
     2761 gataacgata catcaaatgt ctaataagag ttactctaaa tttcaagagg aagtatctct
     2821 gaagtatggg tttatcggtc tgaaattgga taagctaagt ttgaccgctg aagttagtga
     2881 ggaatttcat tctgagattc ttagtggaaa ctttacctta tatgattatt tcggtgtagt
     2941 tgagccgaat ttaaatagaa atggtgaact agctagttat aaagggcaat tctttaatga
     3001 tgaaaaagag aattggtata tcgagtatac ccccgttgcg tcgattaaga tgaacaaaag
     3061 acctttaaag attgaattta ctccttcaaa agtttcaaaa aagaattttt taattgtctt
     3121 tcatagaatg tttccgtaca tgtttaacat cgcaatctct acttttcatt tagcttatga
     3181 ttttgagcga gatttatctg ctttacgtgt aaattggcca aaagtaatgt atcgtcctat
     3241 ttataagggg atgaaacttg agactatgga ttttggtgct cctaaaggta attatcatct
     3301 aactgcttat aataaactta aagaacgtat ggatagtgga gatatggcag aaatagaaat
     3361 ttatcagcaa tatgataatc tatggaggat tgagtataaa ttctacaatg aaggcaacat
     3421 aaaaaaagaa ttaaaaaatg gattaccatt cttagctaaa attccagtgt atattgaaaa
     3481 tttcaaaggc ttagaattta ataatttagg agttaatgag aagatttatc ttttcgctct
     3541 tcgtaataaa cctgaattat ttgcagaatc tgataaacga acggtagcta agtataaaaa
     3601 acttgccgaa agtatctctg aagttaattt gaatgtcttt tttcaaaatg ctttagattt
     3661 tgttgaaatc tttaatcaag agccttgtct gataaatttt tttgagttta tgaattctat
     3721 gttacaaggc gatattccaa agttaacaat aaaccaagaa taataagagg ggaacagtat
     3781 gaaagatacg atttctaata aggatttgat ttccatgggc tatagaccat caacagcaaa
     3841 tgctattatc catcaggcga gagaattact tgtatcacga ggctatacat tttataatcg
     3901 caaacgtttg atggttgttc caaaaagtgt tgtgaaagag ttgttgggaa tggaattgtg
     3961 aaatggctta tatcgagtat agacagcgag gtaagaagaa gctttggtct ttttctataa
     4021 gagaaagaag caagagccta ctccataaaa gcggatttaa aacaaaacga gaagctaaaa
     4081 tagaagcgga gaaagttctt cataagttaa atactgggag tgtcttaagc tctagtatga
     4141 ctttatcgga gctttataat gaatggcttg atttaaaaat tttacctagc aatagaagtg
     4201 tagttactaa aaaaaaatat cttatgagaa agaaggtcat cgaaaggtta tttggaaata
     4261 agcctgtatc acaaattaag cctagcgagt atcaaaaaat tatgaatgag tatggagaga
     4321 ctgtatcgag aaatttctta ggaagattga attctagtat tcaggcaagt atacagatgg
     4381 ctattgctga taaggtgata atagaggatt ttactgctta tgttgagttg ttctcttcta
     4441 agagtggaca aaaggttgag gaaaaatatt tacatactga gtcagattat caaaaagttt
     4501 tagtatattt gaaaaataag tttgattatc agaaatctat tgtaccgtat gtaatttatt
     4561 tcctttttaa aactggcatg cgtttctccg aattgattgc tctaacttgg gatgaagttg
     4621 acgagcttaa tgagcaactt aaaacttatc gtcgttacaa caccgctatt cataagttta
     4681 ctccacccaa aaacaatact tcaataagat tagttcctat tacttcagat atgctttcct
     4741 tgttaaaaac attgaaaata ttgcaattaa aaacaaataa agaattaaat attgataatg
     4801 aaaataattt gatttttcag cattttggct atgtctacga tgttccagat attgcaacag
     4861 tcaataaagc tataaaagta atgttgaagg aattgcaaat ttttccattg attactacca
     4921 aaggagctag acacacttat ggtagttatt tatggcataa taatattgat ttgggagtta
     4981 tagcgaaaat tttaggacat aaagatatct ccatgttgat tgacgtttat ggtcacacct
     5041 tggaggaaaa aattagtgag gagtttatgg ctgtgaaaag tttgttgtaa aaacacggca
     5101 aattgcacga caatttttaa aaggaaagca aaaaaacctt ggttccaagg cttttcctgt
     5161 tgtatttata tgccccctac agggatcgaa cctgtgaccc acggattaag agtccgctgc
     5221 tctgccagct gagctaagga ggcaaagaaa aaagctgtat tggtgccgaa acttcacggt
     5281 ttgtattgaa cccgcgcaat taagcaggtg ggcaactcgc tctaactgaa gctgtttccg
     5341 tgtgagacgg cctacatgct gttagaagac ttttgtttcc ctaataatac aaaaaatagt
     5401 cggtcaacac ttaagtgtga agtcgtacac cacagcgttt ctatatttat atgataccac
     5461 tttttcaaaa aaaatcaaga ggaaagtgca attttttgaa aaggatttca gatttttcgc
     5521 aaatggtcga tagcttcctt tctttgagcc aaagcccgtt catatttacc agtatcttct
     5581 gcttggaaat agtgatgatt acgaattttt tctggcagat agtcttgctt gacccaattt
     5641 ccaggatagt tgtgtggata gagatagtct tgggcattcc ccagttcctt gcttccactg
     5701 tagtgcccat cacgcaggtg tcgcggaata ggcaagtgcc ctgatgtttt gaggtcagca
     5761 agtgccttat ccatagctac ataggctgag ttggattttg gagaaagggc caaatcaatc
     5821 acgacattgg caatgagaat gcgggcttct gggaacccaa tcttctgggc agcatccaga
     5881 gcagtcacgg tatgaatctg ggcctcagga ttggctaaac cgatatcttc ataggcgata
     5941 acagtcaagc gacgagcgag actaggcaga tccccagcct caatcaagcg ggcagcatag
     6001 tggagactgg catccacatc tgagccacgg atagactttt gcagggcaga tagaacatca
     6061 tagtgaccgt ctccatcctt gtccatagtg atgtagcttc tctgaagact attttccatg
     6121 atgtctaagg tgatgtggcg aatgccctcg tcattctcag gggtagagag aacagccaag
     6181 tccagtgagt taaaggcaga gcgaaggtct ccgtttgtag aggttgcgat gaaatccagc
     6241 gcatcctcat ctagttctat tggaaaatta aaaccacgtt cagggttact tagagctatc
     6301 tgcagggcct ctttgacgtc ttggttagac agaggttcca actcaaaaat ttgaacacgg
     6361 ctacgaatgg caggagtgac ggaaaagaaa ggattttcag tcgttgctcc aatcatgatg
     6421 accagtccac tttccaagag aggcaagagg aagtcttgct tggtcttatc tagtcgatga
     6481 atttcgtcta gcaataggac gagaccacca gaaaatttag cttcttccga gatttcttgc
     6541 agtcgctttt tactatcaac tgtcgcattg aaagttcgaa aggcatactt ggtcgttcca
     6601 gcgatggcag aggcaatact ggttttgccg attccaggag ggccatatag aatcatggag
     6661 gacaggcggt tggcttccac catgcggcgg atgatttttc caggtccgac cagatgctcc
     6721 tgaccgatga cctggtcgat ggttttaggg cgcatgcgaa gcgcgagatt gtctggcata
     6781 gcagtccttt ctagcgtgga tttgagtaga atgactcatc tactatatct tactatgtcc
     6841 attctagcct attagttgtg atatttcaat ggttttgtaa taatcaggga gtgagataga
     6901 atctttttta ctatttaatt taatgaggag aggtatcagc atgagagatt tgattttcct
     6961 taaagctcaa aataggatag ttgagcctaa agaagtggaa gtgctgactt gagaaataat
     7021 attgctgaat gtcattgtat gaactataat gaaaagagag gtgataagca atggaaatga
     7081 tggaccaagt caggaaattt tgatttttac aaaacaaatt cgtcattgga ttcttagtga
     7141 tcaagttatt tcagggaaaa gaaaactttt cttccgggaa gatactccaa aagagatttt
     7201 agatttgtac gaaaacatta aatctaaact tgattttgct taccaagaag ttcattctaa
     7261 taatgggttg aaaaaatatg aaaaatagaa taattgatgt ttttgaagta gtaaatcgcc
     7321 tccttgtaat aactgttgaa aatcctgatt tcgaagactt gagagttaat catactcaat
     7381 gaaaatcaaa gagcaaacta ggaaactagc cgcaggctgt acttgagtac ggtaaggcga
     7441 cgttgacgtg gtttgaattt gattttcgaa gagtatcagt ttgtaaaaat tggagataaa
     7501 aaatatagag tacgcagtgg tcctatgatt cattcaactc cgcctcaatc tgtcttagat
     7561 cgagatactt ttacaattga ctatacagat gatgaattgc tcgataaaga agcagttttt
     7621 actactcatt agaaaaatag gtctgaataa attggtttcc cttagaacca catctagggg
     7681 cttttatgta taatagaata ataagtatca ctcctttaca atacgtgtaa cacgtgttat
     7741 aatggtgttg tcaggaggta aaagcgctat acctatgaca caaaaagaga tggttaaact
     7801 ccttacggcc catggttgga taaagactag aggcggtaaa ggctcccata ttaaaatgga
     7861 gaagcaaggg gaaagaccta tcacaatcct tcatggtgag ctgaataagt acactgaaag
     7921 agggatagga aagcaagctg ggttgtaaaa ttcagtccct gctttttgat atggaggtag
     7981 tgaaatgtta gttacgtatc cagctttatt ttattatgac gacacagacg gaacagaagc
     8041 gacttatttt gtccatttcc cagattttga atactcagct acacaaggag aggggatttc
     8101 tgaggctttg gctatggggt cggagtggct agggataact gttgcagatt tgatagagag
     8161 tgatggagag ttacctcagc catcagatat caatagcttg tctttaattg ataatgatcc
     8221 ttttaaagat gatgaagatt tcgtgtcaac ctatgacctt gataaatctt ttatttctat
     8281 ggtatctgtt gatgtatcag aatacctagg aagtcaggaa cccattaaaa agactttgac
     8341 cataccaaaa tgggcagata agttgggacg agaaatggga cttaactttt ctcagacttt
     8401 gacagacgct attgcagata agaaagttca agcctaagat taagcgtggt atcgtggtaa
     8461 tagtcaataa aaaagcacgt ccacttgtgc tagttactcg cctattgatt ttatagattt
     8521 attagccctt tcgagggctt tttatattga tttttatgag aaatgaagaa atcagacttt
     8581 taagaaaatc attgatacca agggtttaaa tgaggtaata tggtataatt aggacataaa
     8641 ataattttgt ggtaagatgg tagtatctat tttagcatat ttccgagcaa tcggggcgat
     8701 taaagagtcg catagaaaga ggacaaaatg gcaacatacg gatttttaga tattttagag
     8761 gaagagttgg acaagaactt tccctttgac tttgagatta gttgggacaa gcgtaaccat
     8821 gcggtagaag tgagttttct attggaagcg caaaatgctg caggtgtgga gatggtggat
     8881 gaagacggag aggttttatc agatgacatt ctttttgagg aagcggtcct tttctacaat
     8941 cctgccaagt caacagtcaa tgaggaagac tatttgactg ttattcctta cctgcctaaa
     9001 aaaggatttt cccgtgaatt tttagcttat tttgcgcttt tccttaaaga tactgctgag
     9061 gttgggctag atgtcctcat ggactttttg gaagacccag aagcagagga atttgtcatg
     9121 gaatggaacc aagaagtctt tgaagaagga aaagttggct tggaagaggg agaattttat
     9181 ccttatccaa gatactagga gttggttgga ggtgttatga agaaaattgg gacttatttg
     9241 gtttatgtgc tagctgttgt ctttattatg ctagcttttg cttgtggaac aatcgcattt
     9301 gcagagttgg ggtattccgc agttttagcc tttacttttg gttatgcctt cgctcttcta
     9361 agcatgtatt taatttttat tcttcatgag ctgggtcatg ctttttgtgg ctacttgaca
     9421 ggctatcggc tggtggcttt tggattagga cattttattt tgaccaaaaa gtcaggcagg
     9481 tttcatctta gtagaacagc cattctgaaa aatgttggtg ctcaatacat tggtttaaaa
     9541 gaggatgaaa gcgatcaaag aatcatcctg atgctttcag gaggcttgat ggttcatctc
     9601 ggcttgatat tattggcgat agtgtttgga tttttgacaa gaagctggta ttttgcaggg
     9661 acttggattt ttcttaattt atctttcttc ctaaataaca ttttgccagt cgacatcacc
     9721 gatggagcaa aaatttggga attactacaa caccctgaaa ataccaaata cgcctacctg
     9781 gtattgagac attctgctca aactttgctg gctcctcaag aatatgattt gaaagacttt
     9841 gttcaagcag ttcctgagga tgcacgaggg agttttgcgg atggtgtatt aggtatgcaa
     9901 ggtgaagttt ccattttgga agggaaggaa gaagtagcta aacagcagtt tcaagcatta
     9961 cttgagaggg caactactcc gatgatgcag acagttgccc aactatccct gcttcatatc
    10021 gccttgttgg aaggagattt tgagcaagcg gagcaatatg ctagtattcg acaggtcaaa
    10081 tcgtttctgt ctctcaaact gtccaatctt caagtgatac aagcctggta tcaattaaag
    10141 gtgaagaaag atgtagatcg aactcgtaag gctctcaaga ttgctagaca gaaaatggat
    10201 agtagtcgaa tgttgaggga cgagaaacgc tattatgaaa acttgttagc cgagctggaa
    10261 aaggaaatgt tagaaggaac tgaagatgga actagaaatt tctggtttcc caggctgtaa
    10321 gattgctttg ttttgtgagg ataagctctt gactatctta cgtgatgata aggcaagtat
    10381 tccctgggcc aatatgtggg aactgccagg tggtggacgt gaaggtgatg aaagtccttt
    10441 tgagtgtgta gcgcgtgaag tttatgaaga actgggcatt catctgactg aagattgtct
    10501 gctttggagt aaggtttacc caagtatgct ttttgcagac aaacagtccg tttttctagt
    10561 tggtcagttg acacagaacc agtttgacag tatcgtattt ggagatgaag gacagggcta
    10621 tcagctgatg aatgttgagg aatttcttag ttccagtcaa gttgtccctc agttgcaaga
    10681 gagattaaaa gattatttaa aagtaagtga ttagaaagga tggttcagtt aaatttctaa
    10741 actgaacccg ccctaaacac tgtgccaaaa agataaactt ctcttagaca caagcgtctt
    10801 cagagaattt cctattttgg ttttgtgttt tacgggcttg gtatcttaat aatggaaaca
    10861 tggcaagagt taaaagttac agtgaagcgt gagggagagg agttggtttc caatctcttg
    10921 attgagctgg gagcgcaagg agtcgcaatc gaagacagta tggactatgt gggaaatgtt
    10981 gaccgctttg gcgagatttt cccagaggtg gagcagcaag aagaaatcgt tgtgacagcc
    11041 tactaccctg acacggtgga tgtgacagtg gttgaggcgg acttgcaggc tcgcatatca
    11101 gaattgacgg attttatgga tttgggagag ttaaaaatag gtacgactgc cttggctgag
    11161 gaagactggg cagacaactg gaagaaatac tatgagccag ctcgtatcac tcatgatttg
    11221 accatcgttc cctcttggac agactatgag gcgactgcgg gagaaaaaat tatcaagctg
    11281 gatcctggca tggcttttgg tactggaacc cacccaacta ccaagatgag cctttttgcc
    11341 ttggaacagg ttcttcgtgg tggcgaaacg gtgctagatg tggggactgg ttcaggggtt
    11401 ctctctattg ccagctcgct tctgggggct aaagaaattt tcgcctatga cctggatgat
    11461 gtggcggttc gtgtggctca ggaaaatatt gagctcaacc ctggcatgga aaatatccat
    11521 gtagcggctg gagatttgct taagggtgtg gaaattgagg cagatgtgat tgtggctaat
    11581 atcttggcgg atatcctcat tcatctaata gacgatgcct atcgtttggt taaggacgaa
    11641 ggctacctga tcatgagtgg cattatcaag gacaagtggg acatggtgcg ccagtcggct
    11701 gagtcagctg gatttttcct cgaaactcac atggttcaag gggaatggaa tacctgtgtc
    11761 tttaagaaaa ccaaggatat ctctggtgtg attggaggct agcatgcagc agtattttgt
    11821 aaaaggcagt gctatctctc ctgtcactat cgaggacaag gaaaccagta agcatatgtt
    11881 tcaggttatg cgcttgaaag aagaggatga ggttacctta gtctttgatg atggcatcaa
    11941 gcgcttggcg cgcgtgctgg atatggaaaa tcgtcagttt gagttggtcc aagaattaaa
    12001 tgacaatgtg gaactaccag tccaagtgac catcgcatct ggatttccca agggagacaa
    12061 gctggagttc atcgctcaaa aagtaaccga actgggtgct agccaaatct gggcctttcc
    12121 tgcagactgg tcagttgcca agtgggatgg caagaaattg ggtaaaaaag ttgaaaaact
    12181 agaaaaaatt gcccttggag cagccgagca aagcaagcgt aatattgtac caagtattaa
    12241 acttttcgag aaaaaagcag attttctagc tcagctggac cagtttgact ttatcatagt
    12301 agcctatgaa gaatcagcta aagaaggaga agccgctgcg cttctgcaag cagtcactgg
    12361 tcttgaaaca ggagccaaac tgctctttat ctttggtcca gaaggcggtc tctcacctgc
    12421 agaaatcgaa agttttgaag ctaagggagc cgttttggta ggcctaggtc ctcgtatttt
    12481 gcgagcagaa acagcaccgc tttacgcctt atcagccctt agtgttttag tagaattaga
    12541 gaaataagag gaagaaaatg gaacaaaaac accgttcaga atttccagag aaggaactct
    12601 gggacttaac agccctatac caagaccgtg aggatttctt gcgtgcaatc gagaaagctc
    12661 gtgaagacat caaccagttt agccgtgatt acaagggcaa tcttcacact tttgaggatt
    12721 tcgagaaggc ctttgcggaa ttagaacaga tctacattca gatgagccat attggcaact
    12781 atgcttttat gcctcagacg acggactata gcaatgacga atttgccaat attgcccaag
    12841 ctgggatgga atttgaaaca gatgccggcg tagccttgac cttctttgac gatgccttgg
    12901 tggtagcaga cgaggaagtc ttggaccgtt tgggtgaatt gcctcacttg acggcagcta
    12961 ttcgtcaggc caaaatcaaa aaagcccact atctaggggc tgatgtggag aaggccttga
    13021 ccaatctcgg tgaagttttc tatagtccgc aggacattta tactaagatg cgagctgggg
    13081 attttgaaat ggctgacttt gaagcccatg gcaagaccta taaaaacagc tttgtcacct
    13141 atgagaattt ctaccaaaat cacgaggatg ctgaggttcg tgagaaatcc ttccgttcct
    13201 tctcagaggg acttcgtaag caccaaaata cggctgcagc agcctatctg gctcaggtca
    13261 agtctgaaaa actcttggct gatatgaagg gatacgactc tgtatttgat tatcttctag
    13321 ctgaacaaga agtggaccgt gtcatgtttg accgccagat tgacctcatc atgaaggact
    13381 ttgcaccagt cgctcagaga tacctcaagc atgttgccaa ggtaaatggt cttgaaaaga
    13441 tgacctttgc agactggaaa ttggacttgg acagcgccct gaatcctgaa gtgactattg
    13501 acgatgccta tgatttggtc atgaagtcgg tagaaccttt ggggcaagaa tattgtcagg
    13561 aagttgctcg ttaccaagaa gagcgctggg tggactttgc tgctaacagt ggcaaggatt
    13621 ccggtggtta tgcggcggac ccatatcgcg tacaccctta tgtactcatg agctggacag
    13681 gccgtttgag cgatgtctat accttgattc atgaaatcgg gcattctggt caattcatct
    13741 tttcagacaa tcaccaaagc tatttcaacg cccacatgtc gacctattat gttgaagcac
    13801 cgtcaacctt caatgaattg ctactcagtg attacttaga gaaccagtct aatgacccac
    13861 gtcaaaaacg cttcgctctg gctcatcgct tgacagacac ctacttccat aatttcatca
    13921 cccacctctt ggaagccgcc ttccagcgta aggtgtatac attgattgaa gaaggggaga
    13981 cctttggagc aagcaagctc aacagcatta tgaaggaagt tttgacagat ttttggggcg
    14041 atgccattga aatcgacgac gatgcagctt tgacttggat gcgccaagct cactactata
    14101 tgggcttgta tagttacact tactctgctg gtcttgtcat ctcgacagct ggttaccttc
    14161 atcttaaaaa ctcagaaact ggagctgaag actggctcaa tctcctcaaa tcaggtggta
    14221 gcaagacacc acttgagtca gccatgatta tcggtgctga tatttcaaca gacaaaccac
    14281 tccgtgatac catccaattc ttgtctgaca cagttgacca gattatcgcc tacagtgctg
    14341 agttggggga gtaaggggat agagaggttg ttatagaatg ggtatggaca gttatttgct
    14401 taaaagtcca tgtttaaatc ccccattcct tttcgaggaa ttctttgccc ttctctgtaa
    14461 tggtaagtga acgtggcgtt tgtgcaggga tgaccaattg tttttcactg aaaaattcta
    14521 aaagagcatt gccgagagct ccgccgacat gatttttacg ttcgctccaa tccaaacatt
    14581 tagggcaaaa tttccgtttt ttctttttca attcatccgt gtcaatgtgt aattttcttt
    14641 ggaaataaga cttcccagct tcagtgagtt ggaagtcttt ttctgattcg ctgaggagat
    14701 tttcttgcaa gagataattg gtaatggaaa tgccaagctc accagcaata tggtcatagc
    14761 aggtgcgagc gacctttaat tcctttttgt gaatgtgttg tttataactt ttgacatcac
    14821 gctgaggaga gtagaagctg agaaattcca gcatttctgc aatggcagca ctttttaaag
    14881 aataataatg aaaacgtcca taggtttgta gagtggttac ctgcgcttcg gtaagtaatt
    14941 tgaggtgata gctgacagta tgttgcttga ttttggtaaa gctggcaatt tcgttaaccg
    15001 tgtgagcttt tccatccatt agaatatcta aaatgtgcat ccgagaaggg tctgataaga
    15061 gttttgtgat gatgaaaata tctggttcca taaaaatttt ctccaaattt catatatcga
    15121 tgattttcta tcttttatta tactataatt aaagcacaag aaaaatagat tttaaaaatg
    15181 ttttactaga gaatatttta aattttattg tctgagttta aatggaggta aaattacaaa
    15241 agtaattgca gcagtatcca cagttgaagg acgttaatct taagattaca ttctcaacat
    15301 tttttcaaaa gtgagatgaa ttaacaaagt atccaacatg ctctatttgt gggggaaaga
    15361 aagagtgaag aagttaagtg ttaaaaatct aaaaaagcaa tatggttctt atgaagctgt
    15421 caagggaatt agctttgaat tgggagaagg agagtgtttg ggtatcttgg gaatcaacgg
    15481 tgctggcaaa acatccactt taaagatgat ttactcactg acctcaattt cctcaggaga
    15541 gattgatatc ttggggcaaa atattgaaac caatcgtcgt aagagtaaat cttgtctggg
    15601 tattgtaggg caggaggata tgctggacat gaccttgaat gtttatgata atctttttgc
    15661 tcacggtcta tgctatggta tctcatctgt cgaacttagg aagagaatcg attctctctt
    15721 ggattttgtt caactgagca aacatgcgca aaagatggtg aatcagctgt cgggtgggat
    15781 gcgacgacgt cttgtcttgg caagagctct catcaatcgg cctgatatta tcattttaga
    15841 tgaaccgaca gttggtttag acattcaatc ccgcaatatt atttgggata aacttttgga
    15901 gttgaatgaa ttaggtgttt ccatcattat tacttcccac tatatgaatg agattgaata
    15961 tttgacagat agggtgctga tgctccacca agggactatc aaagaagaag gaactgtaga
    16021 agacttgctc atcaagtatg atgctgacaa ccttgagacg ctttttttgg ggttgactgg
    16081 gacagagaag gaggacttgc atgtttaagt tatcatttca ctccatcgga cacgttgtgg
    16141 tacgcaacta catgagtttt agaaatttat ttaaaatttc aattgtcccc aaccttatcg
    16201 accccctctt ttatctttta gcaatgggat ttggagttgg tgcttatttg acgcatgtta
    16261 acggtatgct ctaccgtgat tttgtcatta caggtttaat tgctgcgact gccatgtctg
    16321 cggccaccgc agaaacaacg gtcaatgcct ttatccagta taagattgaa aagacttatg
    16381 atgctatgtt gctgacgcca atcaatacga atgatattgt ggtgggtcag gctatctggg
    16441 caggtattcg tgcagtgatt tttggtggga ttttttggct gatttccata cttatcacag
    16501 cgcattttca tgtcttgatg ttattgattc ctctgatttt atttatagtg ggttatttgt
    16561 ttggtgtttt aggactaatc tttacctact tggcgccgtc tagggaattt ctgaattact
    16621 acaatgtttt ggcaatccgt cctctttata tgttttcaga taccttcttt cccattactt
    16681 ccttgccccc aatacttggt gatttgactt ggttttctcc cttgtatcac gctacccgca
    16741 tgattcgtat tatatgggga ggtgaggtga caggtttgta tcttcatctt atctggttga
    16801 tagccttggc gctcttgata acggtgcttc ctatgtatat gttacatcgt agatattata
    16861 gatagtctaa ttatttgtga tgttgtagtc atattctaat ttatactaaa cgttattcga
    16921 atttggacag gtatgggaac tgtgcctatc aatattgtaa tttatggaag ttgaaatagt
    16981 acggttcagt ttttaaaata ttgttagaaa ttgttttaaa ttccctaatc aatttgtata
    17041 gtttttattt cactttatta taactagttt ttcgcaattt ttgagacagg aatgtgattt
    17101 ttgtgataag gctctatcat tacaagttta tttgttgtaa tatggaataa atcatttata
    17161 tatcttttca gaaatatgct gtttctctga atataaatgt ctttttcttt ttaacttaat
    17221 tttacaaatt ggtaaggtca tttaagactg cctttttgaa cagttgctag aaatgtagag
    17281 gtattgacca tgtatcaaga tttactaaga aaaatagcag aagaaaaacc aaattataac
    17341 caggaagaaa tccagtggtt gtttgatcat ttgggaaatc cttctccaga aattcgtaat
    17401 gtccttttaa atcaaggctt gcactatctt tcaaaagaaa aggatacaac aggtttctca
    17461 agtcagtatg gttgggttca ttcttttgca catggagccg atttactgac agaggtggtc
    17521 tgtcatccag actttcctat aaacagaatt catgaagtat ttgatatact tggccaacta
    17581 tttaaaagaa tgtcgattct ctttacagat gatgaggatt ggcgtttagc aagagtgatc
    17641 tatgaaccta ttttacaagg gaagttggag caagaacaag tagcttcttg gataaaaact
    17701 gttgattttc cgatagaaga aagggaggat ttttacaaat tttccaactt tagatcctgt
    17761 ctggtggaag tctatgtcca acttgaccag agaaatagtt tacaagatga cctgaaagaa
    17821 gctatccagt cttttcaata ctagggatta gctaatagtt ctatgatttt caaaaaattt
    17881 ccaatcaatt ttcttgaaac cctttcctac ttttgataga ctagtatcta gtttttgaaa
    17941 aaaggagaaa gaaaatgaaa aaatttgttg ctgagttaat cggtacgttc atgcttgtat
    18001 tcgtcgggac aggagctgtt gtttttggaa atggtcttga tggccttggt caccttggaa
    18061 tcgcctttgc ctttggtttg gcaatcgtgg tggcagccta ctcaatcgga actgtttcag
    18121 gtgctcactt gaacccggct gtttcgattg ctatgtttgt aaacaaacgt ttgtcatctt
    18181 cagaacttgt aaactacatc cttggtcagg ttgttggagc tttcatcgct tctggcgctg
    18241 tcttcttcct cttggctaac tcaggtatgt caactgctag tcttggtgaa aatgccttgg
    18301 caaacggtgt cactgtcttt ggtggtttct tgtttgaagt catcgcaact ttcttgtttg
    18361 tattggttat catgactgtg acttcagaaa gcaagggcaa tggcccgatt gctggtttgg
    18421 taatcggttt gtcattgatg gcgatgattc ttgtcggatt gaagattact ggactttcag
    18481 taaacccagc tcgtagcttg gcaccagctg tcttggtagg cggcgcagcc cttcaacaag
    18541 tttggatttt catccttgca ccaatcgctg gtggagttct tgcagccctt gttgcaaaaa
    18601 atttccttgg aacagaagaa taattgaaac tcaaaaagcc ttgctcctca tcttgaggaa
    18661 cagggctttt tcgtatgata ctcttcgaaa atctcttcaa accacgtcag cttcaccttg
    18721 ccgtaggtat ggttactgac tttgtcagtt ctatctgcaa cctcaaaaca gtgttttgag
    18781 ctgactttgt cagttctatc tgcaacctca aaacagtgtt ttgagctgac ttcgtcagtt
    18841 ctatctgcaa cctcaaaata gtgttttaag ctgacttcgt cagttctatc tacaacctca
    18901 aacactgctt tgagtaacct gcggctaact tcctagtttg ctctttgatt ttcattgagt
    18961 atgactttag cggttgtcaa ttttctctgg ataaaggtcg tgttggaaga ggcgttgttc
    19021 tgccaagccc tcatacttag ttccttgctt accgtagttg tagtaggggg cgattgaaat
    19081 gccaccgcgc ggagtgaatt ttccccagac ttctaaatag cgagggtcta gcaagttgac
    19141 caagtctttc ccgatggtgt tgatacagtt ttcgtggaaa tctccgtggt ttcggtagct
    19201 aaatagatat agtttgaggg attttgactc gacacagagc ttgtcaggaa tgtaggaaat
    19261 atgaatcgtc gcaaagtctg gctgagcagt gatttgtccc agcagagaca tatcgaggat
    19321 atggtgacga atgccctgtt ccttagcgat ttctctagta atttgaattt cgaggtgatg
    19381 acgttggccg taggcaaagg tgacagcttc gactgtttca tagtgttgca tggcccagaa
    19441 aaggcaggtt gttgaatctt gaccaccact aaagacgacc aaggctgatt gacgtttcat
    19501 agtactcctt ccaaaatggg aaatgttcag agcatgcaaa aagctcctat tagggagcta
    19561 aaaaatacca aatcgagttt ttttagcgat ggcatatccc aaacatcgta atattctact
    19621 tatatagtaa aatgaaataa gaacaggaca aatcgatcag gacagttaaa tcgatttcta
    19681 acaatgtttt agaagtagag gtgtactatt ctagtttcaa tctactatag tctagcatat
    19741 tttttgaaaa atggcaaagg gcaagaaaaa gagaccaaag aaagtacttg gtctctcgtt
    19801 tgattagctc aattcagcaa tgatggcctt gatttgttct gctgtgtgaa cacctgcaac
    19861 ttgtttgaca acttggccgt cttttttgaa gagaagagtt ggaatagaca tgattccaaa
    19921 agcacgagct gtgtttggat tttcatcaac gtccatttta acgattttca agacatcttc
    19981 tgaaagttct tcagacaatt tgtccaagat tggactttgc atacgacatg gaccacacca
    20041 agttgcccag aagtctacta agaccaaacc gtcttttgtt tcttgttcga atgttgcatc
    20101 tgtaattgct tttgccattg tatttctcct ttttttagtt atattggctt aaatcttgtt
    20161 tcatgagata gaagaagata tctccataag tcccatggta gtccaaatta tgacccttgt
    20221 aagttaattt ttggacaggg tagtagtctg cgacgccgat aaggcaagct tgttgcgaac
    20281 gttcaaagtc ttcataagac tcgaaagtca cagttctttc gttcttgctg gcatctatat
    20341 aggtaatttc aatcatattt aaaactcctt tgtttaatgc taactttatt ttactcctta
    20401 taaaagagaa tgtcaagaaa aatgattgcg cacgcaactt tttttaaaat catcttaaat
    20461 caagaaatcc aaacctgctt ccaagctttc ttcgacagtc ttttgtagcg aggccagtgt
    20521 cttttgccca tcatttgtca ggcagataaa actagagcgt ctatcttgat ggcaacacat
    20581 gcgactgagt agaccgcaat ttttagcttc caagcgagcc accatcctag aaactgcgct
    20641 cgggctcaga tgaagcttat ctggcaggtc aatctggcgt agagattttt cttcagccaa
    20701 gtccagatag tagagcaggt agaactcttt caaggtcaga ctttgctcgc tctgttgggc
    20761 aatggtctct tccaagagac tttcaatttc tttctgacgc cgattgaagt caaaccattt
    20821 ttccaaatag gtcatagtgt ctcctttctt tttagagtca taattataga agaaagtcca
    20881 ttaacgggca gtctttgcgt cataagatga ttgcgcatgc aataattata ctacttttca
    20941 agaatgctgg caagctctgt tttttagtgg ttttattttt tactgtctat atttttggta
    21001 aaaatcaact tttacttgga tgaaggtttt ggcttcacgt aggagttgaa gaagagtggc
    21061 gcgggtttca aactcttctc ttgttttggg cagactgcgg ttccggaaga cttccagata
    21121 acgttcaatt tcatctagca aatcagaagc aggattggtc tggctcagtt gacctgcaat
    21181 ttttgaaaag agttgcgcta agatcaggct ttcactggcg gcaaggtgac aagtgttaat
    21241 ctgttgggcc atgtttctca ggatacgact ttgtcgttgt ctcatctcaa agtagtggat
    21301 atggtagtcg gtctggtgaa agaggtggtc agagtgatcc aaatagacca gtctgagggc
    21361 ttctttcaaa agcgtgtcta attctgctac cagctgtgct cggttgcgtc cgtctcctct
    21421 ggataaatag tatttgaagc gctggaggat atcttttaac ttttcttcca ccagcgtgtg
    21481 gtagtgctgg atttcctctt ctcgtgaagg catgtagaga ttgaccagta aagcaaatcc
    21541 tgtaccaata gcaaagagaa ggaattcatt gactagaagg tctggagagg ttgactcttg
    21601 aaccaagaga tggctaacca aaaccgtgct tggtgtgatg ccaatttccc agcccatctt
    21661 gtaggctaaa ggaacgtaga aggccagata gaggccgaga ctccagatat gaaatccgct
    21721 caagtgaaaa gctagaacac cgatagccag agctagaagc atagaaaaaa gacgattgcg
    21781 agccagtttt aaagtacttc tacgcgtatc agataggctc aagagagcga taattccagc
    21841 cgaaactgct gacgaaagat tgagaaaata agcaagcagg caggcaagac aggtagctaa
    21901 gatgagcttg gtcgtacgtt ggctaataga cataagaatt tcctaataag ttagaataaa
    21961 agcgtaaaag acaagacatg agcaggcttg ccttgatgag ttatttttta cgggttgctg
    22021 cgtattcggc aacggcggta aagaggacat atgtagaaga gttaagggct gtttcacatg
    22081 agtcttggat gacaccaatc acaaaaccaa ccccaacaac ttgtatggca atatcgttag
    22141 aaataccgaa aaggctacaa gcaactggga taagaaggag ggaacctccc ctccggcaat
    22201 acctaaagta ccacaggctg agatagctgc taccacactg aggacaaagg ctgtggcaaa
    22261 gtcaacagga attccaagag tgttaactgc aacaagggtc aaaacgttaa tggtaatcgc
    22321 tactccagcc atattgatag tagaaccgag tgggatagaa acagaatagg tatctgggtt
    22381 gagtccaagg tcatggcaga gtttcatgtt gacaggaatg ttagtcgcag aactacgagt
    22441 gaaaaaggct gtcacaccgc tgacacggag gcagttccaa actagagggt aaggattgcg
    22501 tctcataaaa aagaaggcaa tcaaagggtt gaccacaagg gcaacaaaaa gcatagtcgt
    22561 tactaataga accaataaaa taccgtagtt ggcaaggctt ccgactccct tgtcagaaat
    22621 ggttttaaaa ataagaccaa ggattccaaa tggagtcaga ttgatgatcc attcgacaat
    22681 tttagaagtc acgtcagcga tagtttttag caattcttta ctatttttac tggcttctct
    22741 catagcgatt ccaaaaatga ctgcccaaga taagattcca atatagttag cagtaaacag
    22801 ggcgttgact gggttgtcaa ccagtttgag caagaggttg ctgaggatct gcccaacccc
    22861 atctggtggt gcaatttcag tattggcact atttagggta atttcaatag ggacgatgaa
    22921 acttgctagt acagctacaa gagcagcggc gaaagtccct atcataggat atacaagaaa
    22981 acaacagttt tcatattgct atcttgtccc ttttgatgtt gggaaagggc attggcaacg
    23041 agagcaaaga ctaggatagg agcaacagct tttagacctc caacgaataa atccccgagt
    23101 agcccaatcc ctgagagatt aggaagggtc agtcctagga ttccccacaa agcataccaa
    23161 tcaagatacg cttgacaagg cttgccttat tccaagcatg aatgattctt ttcataataa
    23221 tctccttttt gtgtagtgat tatgattata gtataaatga tagacaaaat caagaatttt
    23281 ctgtctattt tttgaatatt tatggagaat gagactgatg aaaatatggt ataatgaaat
    23341 aaaggagttt tatatgcaaa aatttattca ggcttatatt gaaaagctag atgtgacaac
    23401 cattatcgag aatattctaa ccaaggtcat ttctctttta ctgcttttga ttgtatttta
    23461 tattgctaaa aaaatgcttc ataccatggt gcagagaatt gtcaaacctt ctctaaaaat
    23521 gtctcgtcat gatgtcggac gccaaaaaac catctcacgt ttactagaaa atgtgtttaa
    23581 ttatacgcta tatttctttt tactctactg cattttgtcg attttaggtt tgccagtttc
    23641 tagtttgctg gctggagctg gtattgctgg ggtagcgatt ggtatgggag cccaaggctt
    23701 tctgtctgat gtcatcaatg gctttttcat cctctttgaa cgtcaactgg atgtgggaga
    23761 tgaggtcgtt ctgacaaatg gaccgattac tgtatcgggt aaggttgtca gtgtgggaat
    23821 tcgtacgaca cagcttcgta gcgaggagca agcccttcac tttgtcccta accgaaatat
    23881 cacagttgtt agcaatttct cacgcacaga ctagacctgt tattttaagt aatttgtggt
    23941 acaatagagg gagtttaata aggagaaaag atggttttag aaaagcagtt gggcaatggt
    24001 tgtacctgga tagacctaga cctaggaaag ttgaataaac tagaagacct ttctgaaatt
    24061 tacggtttgg acaaggaaac cattgaatac gcactggata gaaacgagcg cgcccacatg
    24121 gattaccacc gtgaaagtgg gacggttacc tttatctata atgtcctaga cgtaaaaaag
    24181 gacaaggcct actatgagac ttttcccatg acctttattg tcgagcatcg tcgcctgatt
    24241 accattagta ataccaagaa cgcctatgtc attgaacaga tgactcgtta tctggagagc
    24301 catgacacgc tttcgattta taagtttctc tttgccagtc tggaaattat cagcaatgcc
    24361 tactatcctg tcattgagca gatggacaag agtagggatg aggtcaatga cctcttgcgc
    24421 cagcgaacta ccaagaaaaa cctctttgcc ctgtctgatt tggagactgg tatggtttat
    24481 ctgacggcag ctgccaaaca aaatcggatt ttgttagagc atattcaagg tcatgccttg
    24541 tatcgtagtt ttgatgagat tgagagagaa cagtttgatg atgccatgat tgaggctcat
    24601 cagctggtat ccatgacaga cctaatctct cagattttac agcagctttc agcctcttac
    24661 aacaatattc taaacaataa tctgaatgac aatttgacaa ccttgactat catttcagtc
    24721 ttgctagctg ttttggcagt cgtgacaggc tttttcggaa tgaatgttcc cttaccttta
    24781 acagatgagc cccatgcttg gctctatatc agtttggcta gtgcaggttt gtggattgtt
    24841 ttatccttgt tactaaggaa aattgcgaaa aaaagttaag aaaaggagcc agaatggcga
    24901 ttgaaaatta tataccagat tttgctgtgg aagcagtcta tgatctgaca gtcccaagcc
    24961 tgcaggcgca gggaatcaag gctgttttgg tcgatttgga taataccctc attgcttgga
    25021 acaaccctga tggaacgcca gagatgaagc aatggctaca tgaccttcgg gacgcgggta
    25081 ttggcattat cgtagtgtca aataacacca aaaaacgcgt tcaacgagca gttgagaaat
    25141 ttgggattga ttacgtttac tgggccttga agcccttcac atttggtatt gaccgtgcta
    25201 tgaaggaatt ccactatgac aaaaaggaag tggtcatggt tggtgaccag ctcatgacag
    25261 atatacgagc agcccaccgt gcagggattc ggtcaatttt agtcaaaccc ttggtccaac
    25321 atgactcaat caaaacgcag attaaccgaa ctcgtgagcg tcgtgttatg agaaaaatca
    25381 ctgaaaagta cggaccgatt acatataaaa aaggaattta actatggaag aaattctctg
    25441 tattggttgt ggagcaacca ttcagacgac agataaagct ggtcttggtt ttacccccca
    25501 gtcggcactt gaaaaaggtt tggagactgg cgaagtctat tgccaacgct gtttccgtct
    25561 ccgccactac aatgaaatca cagatgtcca gttgacgaac gatgatttcc tcaagctctt
    25621 gcacgaggtg ggagacagtg atgctttagt ggtcaatgtc attgatatct ttgattttaa
    25681 tggatctgtc atcccaggtt taccacgttt cgtctcgggc aatgatgtcc tcttggtagg
    25741 aaataaaaaa gatatccttc ctaagtcagt taagtctggt aagattagcc agtggctcat
    25801 gaaacgtgcc catgaagaag gtcttcgtcc agtcgatgtg gtcctaactt cagcacaaaa
    25861 taaacatgcc attaaggaag tcattgacaa gattgaacac taccgtaagg gccgcgatgt
    25921 ctatgtggtc ggtgtgacca acgttggaaa atcaactcta atcaatgcta ttatccaaga
    25981 aatcacgggt gatcagaatg tcatcactac ttcacgcttc ccagggacaa ccttggacaa
    26041 aatagagatt ccgcttgacg acggatctta tatttacgat acgccgggaa ttatccaccg
    26101 ccaccagatg gctcactact tgacggccaa aaacctcaag tatgtcagtc ctaaaaagga
    26161 aatcaagcct aagacctatc agcttaatcc tgagcaaacc ctatttttag gtggtttggg
    26221 acgctttgac tttatagcag gagaaaagca aggatttact gctttctttg ataatgaact
    26281 caaactccat cgtagcaagc ttgaaggagc tagtgctttc tacgataagc acctgggaac
    26341 tcttctgaca ccaccaaata gcaaggaaaa agaagatttc ccaaggctag tccagcatgt
    26401 ctttaccatt aaagataaga cagacctagt catctcaggc ctaggctgga tttgtgtaac
    26461 aggcatagca aaagtcgccg tctgggcacc agagggcgtc gccgtcgtca cacgaaaagc
    26521 aattatttaa aacaaaatcg ctgagcgaac aaagtgagct catatagcga tagttattgc
    26581 cgtggtgtga ttgccaatct gtagattggc aaggggcaca attgagacca aggctcaatt
    26641 gtgaggtcag gaaatccatt tttcaaagat gaaatctttg gaaaattagt tccgaccgtc
    26701 cctcaccacc taaaataact atcaaaaaac aaggaagaaa attatgtcat taacatcaaa
    26761 acaacgtgcc ttcctcaaca gccaggcaca caccctcaaa cctatcatcc aaatcgggaa
    26821 aaatggactc aacgaccaaa tcaaaaccag cgtccgtcaa gctcttgatg cgcgtgaatt
    26881 aatcaaggtt actctcttac aaaacacaga tgaaaacatc cacgaagtag ctgaaatttt
    26941 ggaagaagaa atcggtgtgg atacagtcca aaaaatagga cgcatcttga ttttgtttaa
    27001 acaatctagc aagaaagaaa atcgcaagat ttctaagaaa gtcaaagaaa tctaagaccg
    27061 aaactccaaa taactgtttt tatagagaaa taaaggggac tagcctatga caatcgaact
    27121 attgactccc tttaccaagg tagagttgga gccagaaatc aaggagaaaa aacgcaaaca
    27181 agttgggatt ttagggggga attttaaccc tgttcacaat gcccatctca ttgttgcgga
    27241 tcaagtacgg caacagttgg gactggatca agttcttctc atgcctgaat accaacctcc
    27301 tcacgttgat aaaaaggaaa ccatccctga acaccatcgt ctcaagatgc ttgagttggc
    27361 aattgaggga attgacggcc tagtcattga aaccattgag ttggagcgca agggtatttc
    27421 ctacacctac gacaccatga agattttgac agagaagaat ccagatacgg attattactt
    27481 tatcatcggt gccgacatgg ttgactatct gcctaagtgg taccgaattg atgaactggt
    27541 tgacatggtt cagtttgtgg gggttcagcg tccacgctac aaggcaggga cttcctatcc
    27601 agttatctgg gtggacgtac cgctcatgga tatctcgtcc agcatggtgc gtgccttcct
    27661 tgcccaaggt cggaaaccca actttctcct acctcagcca gtgctagact acatcgagaa
    27721 ggaggggctc tactgatgtc ctatcaagac tatatcaact gctcccgtga ggccttgttg
    27781 gaaaaaatgg cagagcttct acctgagaaa cgtctaaccc attgtctagg tgtggagcgt
    27841 gccgctatgg aattagctca gcgctttggt gtagatgttg agaaagcaag tctagcaggt
    27901 cttcttcatg actatgctaa aaagttgtca gatcaggaat ttctagactt gattgaccgt
    27961 taccagctag accctgacct caaaaactgg ggcaataatg tctggcatgg tatggtcgga
    28021 atttacaaaa ttcaggaaga tttggatttg catgattcag aaatcctgcg agccattgaa
    28081 gtccatacag tcggtgctgg tcaaatgaca gacctagata aggtcatcta cgtcgcagac
    28141 tatatcgagc acaatcgagc ctttcctgga gtagatgtgg cgcgtgagat tgcaagtcta
    28201 tcgctcaata aggcggtggc ctacgaaaca gctcgtaccg tggagtatct agctcatcag
    28261 ggattcccca tctatcccca aacccttgaa acctataacg cctttgtgca ctatttgaaa
    28321 gagaactaaa tgaagacggc ttttataatc attgatgttc agaatgtttt agtagaaact
    28381 ggattccaga caaaaagtct attgggaaaa atttcttatt tacaaaacca ggctagaagc
    28441 aagaatattg aaattatcta tgttcaacat attgagaact ctgaagctca aacatcagaa
    28501 gattggcagt tatctgcgct tttaaatcga aaacctgctg aaaaggtctt tcagaagaaa
    28561 tataacagta ttttcaaaga aactggctta aaagaatact tggataagca ggggattgaa
    28621 aaattagttt tatgtggtat gcagacagaa tattgtgtgg atacctctgt caaggttgcc
    28681 tttgaatatg gctatcagct tattgttcca gaaggtgctg tcacaacctt tgatggggat
    28741 gacattccag cagaaacgat taatgaattt tatgaggaca tttgggagga gcgctttgca
    28801 gatgtcctag attacaaaca tattttctaa aaagaggatt aaatgaacga aaaagaatta
    28861 ctagaactag tcgtgaaagc ggctgatgag aaacgtgcgg aggatatcct cgcacttgat
    28921 gtacaagatt tgactagtgt gacggactac tttgtcatca ctagctcaat gaatagccgt
    28981 cagttggacg ctatcgcagc taatatccgt gaaaaagtag ctcaagcagg ctttaaaggt
    29041 agccatgtcg aaggcgatgc agctggaggc tgggtcttac tggacctcgg tgctgttgtc
    29101 gtgcatatct tttcagaaga aatgcgtgcc cattataacc tagagaagct atggcatgag
    29161 gcgaattcag tagatatttc agaagctctt gcttagaaga tgaactcagt tgtagtcaac
    29221 tgggtttctt tgcttatttt agaaaaattg atagaaaggt aaagggctag tggtgtttac
    29281 catggagctc ttagtatcat gattatggcg acttatgaaa cctttgcggc ggtctatgat
    29341 gcggtcatgg acgatagttt atacgacaaa tggacaaatt tttctctgcg tcatttgcct
    29401 aagaccaagg agaaaaagaa actcttggaa ctggcttgtg ggacaggaat tcaatcagtg
    29461 cgcttctctc aggctggttt tgatgtgact ggacttgact tgagtgcgga tatgttgaag
    29521 attgcggaga agagagcaac ttcagccaag caaaagattg cttttataga aggtaatatg
    29581 ctgaatttgt ccaaggcagg gaaatacgat tttgtcacgt gttattcgga ctctatctgc
    29641 tatatgcagg atgaggtgga agtaggggac gtctttaagg acgtgtacaa tgcgctgaat
    29701 gaagagggag ttttcatctt tgacgtgcac tcgacctacc agacagatga agtattccct
    29761 ggctattcct accatgaaaa tgcggaagat ttttccatgc tttgggatac atatgaggac
    29821 gaagttcctc actccatcgt gcatgagctg actttcttta tcaaggaggc tgacggttcc
    29881 tttagtcgcc acgatgaagt acatgaggag aggacctatg agatcttgac ctatgatatc
    29941 ttgctggaac aggctggatt caagtccttc aaactctatg cagactttga ggataaggag
    30001 ccaacagaaa ctagcacccg ttggtttttt gtggcgcaga agtaggagat tagcatgacc
    30061 atcacaggta ttatcgcgga gttcaatcct tttcataatg gccataaata cctgctggat
    30121 caggcagagg gactgaaaat tgttgccatg tcagggaatt tcatgcagcg tggagagcct
    30181 gctattgtgg ataagtggac aagggcccag atggcgctgg aaaatggcgc agacttggta
    30241 gtggaattgc cttttttagt cagtgttcag gcagctgatt tctttggtca aggagctgtg
    30301 gatatcttgg atcgcttggg cattgatagt ctagtttttg ggacagagga agttcgagat
    30361 tatcagaaaa tcgctgactt atacacagag aaaggtgctg agatggagaa atttgtggaa
    30421 aatctgcctg attccctttc ctatccccag aaaacccaag ctatgtggaa ggaatttgct
    30481 ggtcttgatt tttcaggtaa tacccccaat catgttcttg ctctggccta tgcaaaggcg
    30541 gttgcaggac gaaatatcaa gctgcatccg attcagcgtc agggggcagg ttaccattct
    30601 gtgaataaag atgtggactt tgcctcggcg acagccctcc gtcaacatca gaaggaccaa
    30661 gatttcttag aacgttttat gccttctgtt gccctatttg agcaggccag taaggtgatc
    30721 tgggaagact attttccctt gctccgctat caaatcttgt caaatcccga cctaaccacc
    30781 atctatcagg tcaatcaaga aatggctgtg cgcattaaag aagctattaa aacagcccag
    30841 tctgtggaag aattggtcga gttagtgact accaaacgtt acaccaaggc gcgtgtcaga
    30901 cgcctattga cctatatttt gatgcaggct agagaaagtg acttgccaga agccattcat
    30961 gtccttggat ttactgaaaa aggtaggcaa catctcaagt ctttgaaagg tcaggtcagt
    31021 ctagtcagcc gaattggcaa agaaccttgg gatgctatga ctcaaaaggt tgaccagatt
    31081 taccaactag gaaagccaag tatagcagag caaaattttg gcagagtgcc gattagaata
    31141 gaaacaaact aagtctaccg aaaggtggac tttttgagat tttttacgaa taatactctt
    31201 cgaaaatcaa attcaaatcg cgtcaacgtc gccttgccgt actcaagtac agcctgcggc
    31261 tagtttccta gtttgctctt tgattttcat tgagtataaa tagatagaaa agaaaatctt
    31321 gtacaagttc ctgacaattt ctttcttttc gtgtataata gtggaaaaga gctaaaacga
    31381 ggtatggtta tggaagcagt cctttactca acattccgaa atcatttaaa ggactacatg
    31441 aagaaggtaa atgatgaatt tgagcctttg acggtggtca ataaaaatcc agatgaggac
    31501 attgtagttc tttcaaagag cgaatgggac agtattcagg aaaccctgag aatcgcccaa
    31561 aataaggagt tatcagacaa ggttttacga ggaatggata aaattcgcgc aggacactag
    31621 tctaatttac agagaatacc tgagtgaaat cttgctgttg ttagaaacaa acttcttgta
    31681 tttcataatc attaggaagt ctactgcaaa gtaggctttt tctcaagtct ctactaaact
    31741 actatttcta aaaaacaagt ttattttggt aaatgtgttc caaattcccc aaaacatatt
    31801 ctattttagg tttgtgaaaa tcactttttt atggtagaat gtaaaagaat gtatgtcatt
    31861 cggaataaca ataaaatgag gtaaaaacat ggagttcatg tcgcttgcga ttgctgtttt
    31921 tgccgtcatc attggtttag tcattggata tgtcagcatc tcagctaaga tgaaatcatc
    31981 tcaggaagct gcagagttga tgcttttaaa tgctgaacaa gaagcaacta atttacgtgg
    32041 acaagctgag cgtgaagcgg atttacttgt taatgaagcc aaacgtgaaa gcaagtctct
    32101 taaaaaagaa gcactattgg aggccaaaga agaagccaga aaataccgtg aagaagtgga
    32161 cgctgaattc aaatcagaac gtcaagaact caaacaaatc gaaagtcgtt tgacagagag
    32221 agctactagc cttgaccgta aggacgacaa tttgacgagt aaagaacaaa cacttgaaca
    32281 aaaagaacaa agtatttctg atagagcgaa aaaccttgat gcgcgtgaag agcaattaga
    32341 ggaagtcgaa agacaaaaag aagcagaact agagcgtatt ggtgctctgt ctcaggcaga
    32401 agcacgagat attatcttgg ctcagacaga ggaaaacttg accagggaga ttgccagtcg
    32461 cattcgcgaa gctgagcaag aggtcaagga acgttctgac aaaatggcca aggacatctt
    32521 ggttcaagct atgcaacgta tcgctggtga atatgtagcg gagtcaacaa actcaacagt
    32581 tcatctgcca gacgatacta tgaagggacg cattattggt cgtgaaggtc gtaacattcg
    32641 tacctttgaa agtttgacag gggtcgatgt gattatcgac gatacaccag aagtggtgac
    32701 cttgtcagga tttgatccga ttcgtcgtga gattgcccgt atgactatgg aaatgttgct
    32761 caaagatggt cgtatacatc cagctcgtat cgaagagttg gttgagaaaa accgtcaaga
    32821 gattgacaat aagattcgtg aatacggtga ggctgctgcc tatgaaattg gtgcgccaaa
    32881 ccttcatcca gacttgatga agattatggg acgtttgcag ttccgtactt catatggaca
    32941 aaatgttttg cgccattcga ttgaggttgc taagttggct ggtatcatgg cgagcgaact
    33001 tggtgaaaat gcggctcttg cccgtcgtgc tggattcctt cacgatatcg ggaaagccat
    33061 tgaccatgag gttgaaggta gccacgttga aatcggtatg gaattggccc gtaagtacaa
    33121 ggaaccccca gttgtggtga atacgattgc tagtcaccac ggagatgttg aagctgagag
    33181 cgtgatagca gttatcgtcg ctgcagcaga tgccttgagc gcagcccgtc caggtgctcg
    33241 tagtgagtct cttgaaagct acatcaagcg tctccatgat ttggaagaaa ttgctaacgg
    33301 ctttgaagga gtgcaaacta gctttgccct tcaagcagga cgtgaaattc gtatcatggt
    33361 caatccagga aaaatcaagg acgacaaagt cacaatcttg gctcacaaag ttcgtaagaa
    33421 aattgaaaac aatctcgatt atccaggaaa tatcaaggta accgtgattc gcgagcttcg
    33481 tgcagtagat tatgctaaat aaataagaaa gagcagttga aaaattactg cttttttgtt
    33541 acactagata gaaagactgt aaaggataat ctggcttttt gccattattc tagagaaatg
    33601 ttatttcaca gattgactaa aaggagacac aatggcagac cgaggcttac taatcgtttt
    33661 ttctggtcct tcaggggttg gaaaaggaac ggttagaaga gagatttttg agagttctga
    33721 aaaccaattt caatattctg tatcgatgac gacacgcgca caacgtcctg gagaagtgga
    33781 cggtgttgac tatttcttcc gtactcgtga agaatttgaa gagctgattc gtcaaggaca
    33841 gatgttggaa tacgcagaat atgtcggtaa ctactatgga actcctctga cctatgtcaa
    33901 tgaaaccttg gacaagggaa tcgatgtttt ccttgaaatt gaagttcagg gtgctcttca
    33961 ggtcaagaaa aaggttccag atgctgtctt tatcttcctg acaccaccag atttggatga
    34021 attgcaagat cgcttggtag gtcgtggaac agatagtgca gaagtgattg cccaacgaat
    34081 cgaaaaggcc aaggaagaaa ttgccctcat gcgtgagtat gattatgcga ttgtcaacga
    34141 tcaggtgccc ctagctgctg aacgtgtcaa atgtgtgatt gaagcagaac acttctgtgt
    34201 ggatcgtgtc attggtcact atcaggagat gttaccaaaa tctccaacta cccgataaaa
    34261 tttagaaaat aggtacaagc aaatgatgtt aaaaccctct attgatacct tgctcgacaa
    34321 ggttccttca aaatattcac tcgtaatctt ggaagcaaaa cgtgcccacg aattggaagc
    34381 aggtgcccca gcaactcaag gtttcaagtc tgaaaaatca actcttcgcg ctttagaaga
    34441 aatcgaatca ggaaacgtta caattcaccc agatccagaa ggaaaacgtg aagcagtgcg
    34501 tcgccgtatc gaagaagaga aacgccgcaa agaagaagaa gaaaagaaaa tcaaagagca
    34561 aattgctaaa gaaaaagaag atggtgaaaa aatttaaggt tggggggact caatcttatt
    34621 ttttctattg caagaatgta ctgacaagga ggaggtgaga agatggccct agctaagatt
    34681 atcgtagatg tgcccttgat gcagacggac cagccctata gttacaggat tccggaggaa
    34741 tttgagggaa tgctggaagt tgggatgcgg gttcatgtac cttttggtaa gggtaatcgc
    34801 ctgattcaag ggattgttct tggtttggag tcccaatcag atggagaaga gatggagcaa
    34861 gatttaaaag atattgcaga ggtgctggat ttttctcctg ttctcacgcc agaacaactc
    34921 tggctggctg aggagttacg caaatctgtc ttctcctaca aaatctctat cctcaaggcc
    34981 atgcttccag gatttctgaa ttctagctat gacaagattc tctatcctct ggaaggcttg
    35041 agtcaggaag aacgagtacg cctgtttggt tcagaagatt cgctagcctt ttcttcacta
    35101 gaccttgcca agcaagctga aatgatgcgt ttgactagaa aaggcctgct tggtctggaa
    35161 tatcaggcag tcgatcaaaa gaaggtcaag acccagtctt ggtatgaggt tgaccatgcc
    35221 caattagaag gtgttgagat ttctacacgt gccaagaaaa agttggaact gagagattat
    35281 ctgctgtctc atccagagag cgcttccttg gctagcttgt tagagtccta ctcgcgagag
    35341 caagtcaact tctttgtgga tcaaggtgct gttaccatag tccaaaagga agttcaacgc
    35401 tcggctgctt attttgaagg aattgaagca agtagacctt tggagttaaa tccagaacaa
    35461 agacaggcgc gtgatgcggt tgtgagttct attggcagtt ctcaacctcc ctttctactt
    35521 caagggatta caggaagtgg gaagaccgag gtttacttgc agattatcca aggtgccctg
    35581 gataagggca agacagctat tttgctggta cctgagattt ccttgactcc tcagatgacc
    35641 gagcgtttta tagcacgttt tggggacaag gtagccattc ttcactcagg attatccaat
    35701 ggtgaaaagt atgatgaatg gcgcaaggtg gagcgtggcg atgcccaagt tgttgttggt
    35761 gccagatctg ctatctttgc tcctctgaaa aatctgggtg tcatgattat tgatgaagag
    35821 catgaagcgg cttataagca ggacagcaat ccccgttacc atgccagaga ggtagctatt
    35881 ttacgggctc agtataatca agcaactctg gtacttggat ctgcaacgcc gagcttagag
    35941 agccgggcgc gtgctggcaa aggcgtctat caacacttac gtctaaccca acgtgccaat
    36001 cctttggcta caatccctga ggttcaagtg attgactttc gagactatat cggacaaaat
    36061 gagacgtcaa actttacgcc tcctttgcta gaggctatcc aagaccgtct ggttaaaaaa
    36121 gagcaggtgg ttctcatgct caatcgccgt ggttattcta gctttgtcat gtgtcgggag
    36181 tgtgggacgg tggatacttg tcccaactgc gatatttctc tgaccttgca tatggatacc
    36241 aagactatga actgccatta ttgtggtttc tcgaaggata ttcctcaggt ctgtcctaac
    36301 tgtaagagcc acagtattcg ttactatggg acgggaactc agaaggctta tgatgagcta
    36361 gcagaactct ttccccaagc tcgcattctg aggatggatg tggatacgac tcgaaaaaaa
    36421 ggcagtcacc aagccttgct tgatcagttt gggcgaggga aagcggatat tttacttggt
    36481 actcagatga ttgcaaaggg tttggatttt cccaatgtta ccctagtcgg agttctaaat
    36541 gcggatacgg ccttgaatct gcctgatttc cgttcttctg agagaacctt ccagctcttg
    36601 actcaggtgg caggtcgagc aggtcgggct gaaaaagcag gtcaagtctt gatacagtcc
    36661 tacaattcgc agcactatgc tattcgattt gccaaggatc aagattacga aggcttttat
    36721 gcctatgaaa tgggaatcag acgacaactc ggctatccac cttactattt cacgattggt
    36781 attacccttt ctcacaagaa agaagaagag gttttcaaac gtgcctatga agtcatgaac
    36841 attttgcggt caggcttgtc agagaccagt cccattctgg ggccaacgcc aaaaccgatt
    36901 gcccgtaccc acaacctcta tcattaccag attttaatta aataccgttt agaagatgag
    36961 ctggggccga ccctcaacca ggtcttggcc ttgactcaag aacgggaaaa tagtgagctc
    37021 cgtctcagca ttgaccatga gccgcagcaa tttttataaa aaggagaaga tatgacaaaa
    37081 ctaatcttta tggggacccc cgacttttca gcaacagtct taaaaggact tttgacagat
    37141 gaccgttacg aaattctagc cgttgtgacc cagccagacc gtgctgttgg tcgtaaaaaa
    37201 gttatccaag aaaccccagt caagcaggct gccaaggaag caggactatc tatctaccaa
    37261 cctgaaaaat tatctggaag tccagagatg gaagatctta tgaagctagg agcagatgga
    37321 attgtgactg ctgcttttgg gcagtttctc ccaagcaaac tccttgatag catggacttt
    37381 gctgtcaacg ttcatgcctc cctccttcct agacaccgtg gtggtgcgcc tatccattat
    37441 gccttgattc aaggggatga ggaagctggt gtgaccatca tggaaatggt taaggaaatg
    37501 gatgcaggag atatgatttc tcgtcgcagc attccgatca cagatgagga caatgttggc
    37561 accttgtttg aaaaattggc gctagttggt cgtgatttgc ttttggacac tctgcctgcc
    37621 tatattgctg gtgatatcaa acctgaaccg caggatacga gtcaggttac cttctctcca
    37681 aatataaagc cagaggaaga aaaactggac tggaacaaaa ccaatcgtca actctttaac
    37741 caaattcgtg gaatgaaccc ctggcctgtt gcccatactt tccttaaggg cgaccgcttt
    37801 aagatttatg aagccctacc agtagaaggt cagggaaatc caggtgagat tctctctatc
    37861 ggcaagaaag aattgattgt cgcaacggct gaaggggctc tatccctcaa acaagtgcag
    37921 ccagctggta agcctaggat ggacattgct tccttcctca acggagttgg acgtacattg
    37981 actgtaggag aacgatttgg tgactaaagt agaaacggct agaagtttag ctctagcagt
    38041 gctagaggat gtttttgtga accaagcata ctcaaatatc gccttaaata agcatctaaa
    38101 gggaagtcaa cttttggcag cagacaaggg cttagtgacc gagctggtct atggaacggt
    38161 agcccgtaaa ctgactctgg aatggtacct atcccacttt atcgaagaca gagaccagtt
    38221 agacagctgg ctctatgtcc ttcttctcat gagtgcctac caactccgct atttggacaa
    38281 gattccagat catgctgtgg tcaatgaagc agtggaattg gccaaacttc gtaaaaaagg
    38341 cagtgaaaaa ttggtcaatg ccctccttcg ccgtatcttg cgtgaaggct ggccagatat
    38401 ttctagcatc aagcgaaaaa acaagcgtga ctccattgcc tattctctcc cagtttggct
    38461 agttgccaaa ctcaaggaag aatacggaga ggagagagca aaagccatct ttgaaagctt
    38521 gttagtgcga aacaaagcca gtattcgtgt aacagaccta agtcgaaaag aggaaatcca
    38581 agccttgttg gaggcgaata attccctttt agcaaccact ggtctggtta aggagcaggg
    38641 gcattttgca gggcataatt tgtttgcgga tggagccatt accatccaag acgagtccag
    38701 tcagctggtt gctccgacgc ttgatttaca aggtgatgag cgagtgcttg atgcctgtgc
    38761 ggctccaggt gggaaaacag cccatatagc ctcttatctt acgacaggtc aggttactgc
    38821 tctggacttg tacgaccaca agttggattt aattcaagaa aatgcccaac gtctgggagt
    38881 tgcagatcgg gttcaaactc aaaaattgga tgccagaaag gtgcatgagt tttttgacca
    38941 ggattccttt gataagattt tggtggatgc tccttgttca ggaatcggtc ttttgcgccg
    39001 aaaaccagat atcaaataca ataaagaaac ggcagatttc gcgtccttgc aggaaattca
    39061 gttagaaata ttaggtagtg tttgtcaaat actaggcaaa ggtggtataa taacttatag
    39121 cacctgcact atcgtctcag aggagaattt tcaagtcgtt aaggcctttt tagagagtca
    39181 tcccgagttc gagcaggtaa aactagaaca tgaatgtaag gatatcatga aagacggctg
    39241 tatcctcatt acacctgaat tgtatggaag tgatggattc ttcatcagtc aatttcgcaa
    39301 gatatcggat taggaaggaa ctgacacatg gaaatttcat tattaacaga tgttggtcag
    39361 aaacgaacaa ataaccaaga ctatgtcaac cactatgtca atagagctgg acgtaccatg
    39421 attattttag ctgatgggat gggaggtcat cgcgcaggga atatcgctag tgaaatggcg
    39481 gtcacagacc tgggtgtagc ttgggttgat actcagatcg atacagtcaa tgaagtgcgt
    39541 gaatggttcg cccattacct agaaattgaa aatcaaaaga ttcaccagct tggtcaggat
    39601 gaagcttaca gaggcatggg aactactttg gaagtccttg ctattattga taatcaggct
    39661 atctatgctc atattggtga ttcgcgtatc ggcttgattc gtggagaaga ataccatcag
    39721 ttgacgagtg atcattcttt ggttaatgaa ttgctcaagg ctggtcaatt gacaccagaa
    39781 gaggcagaag ctcatccgca aaaaaatatt atcacccagt ctattgggca aaaagatgaa
    39841 attcagcctg attttgggac agttatcctt gagtcaggtg actatctctt gctcaatagt
    39901 gacggcttga ccaacatgat ttcaggcagt gagattcgtg atattataac cagtgatatt
    39961 cctttagcag ataaaacgga gacacttgtt cgttttgcta acaatgcagg aggtttagac
    40021 aacattacgg ttgcccttgt ttctatgaac gaggaggatg aagaatgatc caaatcggca
    40081 agatttttgc cggacgctat cggattgtca aacagattgg tcgaggaggc atggcggatg
    40141 tctacctagc caaagactta atcttagatg gggaagaagt ggcagtgaag gttctgagga
    40201 ccaactacca gacggacccg atagctgtag ctcgttttca gcgtgaagcg agagctatgg
    40261 cagatctaga ccatcctcat atcgttcgga taacagatat tggtgaggaa gacggtcaac
    40321 agtatcttgc aatggagtat gttgctggac tagacctcaa acgctatatc aaggaacatt
    40381 atcctctttc taatgaagaa gcagtccgta tcatgggaca aattctcttg gctatgcgct
    40441 tggcccatac tcgaggaatt gttcacaggg acttgaaacc tcaaaatatc cttttgacac
    40501 cagatgggac ggccaaggtc acagactttg ggattgctgt agcctttgca gagacaagtc
    40561 tgacccagac taactcgatg ttgggctcag ttcattactt gtcaccagag caggcgcgtg
    40621 gttcgaaggc gactgtgcag agtgatatct atgccatggg gattattttc tatgagatgt
    40681 tgacaggcca tatcccttat gacggggata gcgcggtgac cattgccctc cagcatttcc
    40741 agaaacccct gccgtccgtt attgcagaaa atccatctgt acctcaggct ttagaaaatg
    40801 ttattatcaa ggcaactgct aaaaagttga ccaatcgcta ccgctcggtt tcagagatgt
    40861 atgtggactt gtctagtagc ttgtcctaca atcgtagaaa tgaaagtaag ttaatctttg
    40921 atgaaacgag caaggcagat accaagacct tgccgaaggt ttctcagagt accttgacat
    40981 ctattcctaa ggttcaagcg cagacagaac acaaatcaat caaaaaccca agccaggctg
    41041 tgacagagga aacttaccaa ccacaagcac cgaaaaaaca tagatttaag atgcgttacc
    41101 tgattttgtt ggccagcctt gtattggtgg cagcttctct tatttggata ctatccagaa
    41161 ctcctgcaac cattgccatt ccagatgtgg caggtcagac agttgcagag gccaaggcaa
    41221 cgctcaaaaa agccaatttt gagattggtg aggagaagac agaggctagt gaaaaggtgg
    41281 aagaagggcg gattatccgt acagatcctg gcgctggaac tggtcgaaaa gaaggaacga
    41341 aaatcaatct ggttgtctca tcaggcaaac aatccttcca aattagtaat tatgtcggcc
    41401 ggaaatcttc tgatgttatc gcggaattaa aagagaaaaa agttccagat aatttgatta
    41461 aaattgagga agaagagtcg aatgagagtg aggctggaac ggtcctgaag caaagtctac
    41521 cagaaggtac gacctatgac ttgagcaagg caactcaaat tgttttgaca gtagctaaaa
    41581 aagctacgac gattcaatta gggaactata ttggacggaa ctctacagaa gtaatctcag
    41641 aactcaagca gaagaaggtt cctgagaatt tgattaagat agaggaagaa gagtccagcg
    41701 aaagcgaacc aggaacgatt atgaaacaaa gtccaggtgc cggaacgact tatgatgtga
    41761 gtaaacctac tcaaattgtc ttgacagtag ctaaaaaagt tacaagtgtt gccatgccga
    41821 gttacattgg ttccagcttg gagtttacta agaacaattt gattcaaatt gttgggatta
    41881 aggaagctaa tatagaagtt gtagaagtga cgacagcgcc tgcaggtagt gtagaaggca
    41941 tggttgttga acaaagtcct agagcaggtg aaaaggtaga cctaaataag actagagtca
    42001 agatttcaat ctacaaacct aaaacaactt cagctactcc ttaaaagcag atggataatc
    42061 aaaatgagta atcaatcttt gtcatgattt catggcaaag attttttttg agtccagatt
    42121 tgtgatagaa tagagggagt tgataaaagg aggaaagcat ggaagaatca aaagaattaa
    42181 atgccgtcat tgatgtgatt atgctagcgg ggactattct ccttaaaagt ggctcagaaa
    42241 tccatcgtgt agaagatacc atgattcgaa tcgcgcattc gcaggggatt gtggattgca
    42301 atgtccttgc catgcctgcc gctatctttt tctctattga aaataccaat atttcgcgca
    42361 tgaagcgcgt gacctcctct tcttataaca tcgaaaaagt ctgcgatgtg aaccagattt
    42421 ctcgtcagct agttgggggg cagattgact tagaaacagc ctttaagcaa ttgacggcct
    42481 tgcaagctca accccttccc tatactaagt tgcaggtaac tctggctgcg acctttagtg
    42541 ctcctttctt ttcagttatg tttagcggaa atatctacga cgcacttggg gcaggagtgg
    42601 cgaccttatt tggttttgcc ttttccctct atgtggaaaa atttatccga attccctttg
    42661 tgacagcctt tgctggagcc tttgtctttg ggataattgc ccagttttgg gctcgctaca
    42721 caggttttcc ttcaacggca gatttgatta tagctggtgc ggtcatgccg tttgtaccag
    42781 gtattgcctt gaccaatgcg gtccgtgata ttatgaccaa ccacataaac tctggtatga
    42841 gtaagatgtt tgaatccctg ctcattaccc tcgctttagg ggcaggaact tctgtcgcct
    42901 tggtattgat gaactaatat gacactaaca acctttttat tacaagcagt agcaagtttt
    42961 cttgccatta tcactttttt aatcgtactc aatgtgcaac ggtctatgct cttacctgga
    43021 gggattttgg gcatgactgt ctggctaatc tatctcttgc tcaaggaacc gaccaatgtc
    43081 attgtagcta ccttcattgc agccattatt ggttcttgtg tcagccagat tttaagtatt
    43141 ctttataaga cacctgctgt ggtctttatc ttggccattt tggcaccgct ggttccaggt
    43201 tatctctcct accgaacaac tgcctttttt gtgacagggg actataataa agcactggca
    43261 agtgcgacct tggttgtcat gttggctttg gtaatctcta ttggaatggc tagcggaaca
    43321 gtgattctca gactgtatca ttatataaaa acacatcgag tatcgtagac tttacagaaa
    43381 taaaagaatt ttctgaaaaa tgagataaat aaattaacaa cgctttctat atgtgcgaga
    43441 ataccgcact tatgaagaaa ttgcggctga ttttggtatc cacgaaagca acttactccg
    43501 tcggagccaa tgggttgaag taactcttgt tcaaaggtgg tgttacgatt tcaagaactc
    43561 ctctcagttc tgaagacacg gtaatgattg atgcgacgga agtaaaaatc aatcgcccta
    43621 aaaaaaacaa ttagcgaatg attctggtaa aaagaaattt cacgctatga aggctcaagc
    43681 gattgtcaca agtcaaggga gaattgtttc tttggatatc actgtgaact attgtcatga
    43741 tatgaagttg ttcaaaatga gtcgcagaaa tatcggacaa gctggtaaaa tcttggctga
    43801 cagtggttat caagggctca tgaagatata tcctcaagca caaactccac gtaaatccag
    43861 caaactcaag ccgctaacag ttgaagataa agcctataac catgcgctat ctaaggagag
    43921 aagcaaggtt gagaacatct ttgccaaagt aaaaacgttt aaaatgtttt caacaaccta
    43981 tcgaaatcat cgtaaacgct tcggattacg aatgaatttg attgctggca ttatcaatca
    44041 tgaactagga ttctagtttt gcaggaagtc tactactttc cttattgtct gtaaatctac
    44101 tgaccttgtt gtttatccca gtcatggttt ctagttcggg ctcagagttt caaagtggat
    44161 ggcaagagca tcaattgatt gctgagaagg ttagtaaaac acttgataag acatttgata
    44221 aggatgtcag agaaattccg accagtcagt tttatcaaaa atttgtagat gagatgggaa
    44281 ggacttactc aggaaatttg atcctccagg agctgataac tgtgaatgga gcttataaag
    44341 ctacttatat cggtgaactc tctagcaact aatcattctt taaaatgatg accaataaga
    44401 ggcttgattt ggtgaatcaa gtcttttttc tctcttttac tgccatttgt gataaaatag
    44461 tatagaacga ttttttacat gaatgataaa acagaggtaa atatgacaat cggtattgat
    44521 aagattggtt ttgcgaccag tcaatatgtc ttgaaattac aagacttagc agaagcgagg
    44581 ggaattgacc ctgaaaaatt aagtaaagga ctcttactca aggaattgag tattgcgccc
    44641 ctaactgagg acattgtgac cttggcggcc agtgctagtg actctatttt aactgagcaa
    44701 gaaagacaag aagttgacat ggtcattgtg gctaccgagt caggaattga ccagagtaag
    44761 gctgcggccg tctttgtgca tggcttgctg ggcatccagc cctttgctcg tagtttcgag
    44821 attaaagaag cctgttatgg agcgactgct gcccttcatt atgccaaatt gcatgtggaa
    44881 aattctccgg agtccaaggt cttggtcatt gccagtgata ttgccaaata cggtattgaa
    44941 actccaggag aaccaactca aggtgctgga agtgtagcta tgttgattac acaaaatcca
    45001 cgcatgatgg cctttaataa tgacaatgta gctcagaccc gtgacatcat ggatttctgg
    45061 cgaccaaatt actcgacaac tccttatgta aatggtgttt attctaccca acaatacttg
    45121 gatagtttga aaacgacttg gcttgaatat caaaaacgct accagcttac tctggatgat
    45181 tttgcggctg tttgtttcca cttgccttat cctaaattag cgctaaaagg cttgaaaaaa
    45241 atcatggata agagcctgcc tcaagagaaa aaagacctct tacaaaagca ttttgaccag
    45301 tctattctct acagtcaaaa ggtggggaat atctacacag gttcactttt ccttggactt
    45361 ttgtctctct tggaaaatac agatagcttg aaagctgggg ataaaatcgc cctttatagt
    45421 tacggaagtg gagctgtggc tgagttcttc agtggtgaat tggttgaagg atatgaagct
    45481 tatttggata aagaccgttt gaacaagctc aaccaacgaa ctgccctatc cgttgcagac
    45541 tatgaaaagg tcttttttga ggaagtaaac ttggatgaaa caaactctgc ccagtttgct
    45601 ggctatgaaa atcaagattt tgccttggtt gaaattcttg accaccaacg ccgttatagc
    45661 aaggttgaaa aataatgaag ataagttgga atggattttc taaaaaatca taccaagagc
    45721 gcctcgagct gctaaaagct caggcgctcc ttagtcctga gagacaagct agtctggaga
    45781 aggatgaaca gatgagtgtg actgtggcag accagctgag tgagaatgtg gtgggaactt
    45841 tttctctgcc ttattcgctg gttccggagg tacttgtcaa cggtcaggaa tacaccgttc
    45901 cctatgtgac agaagaaccc tctgtggttg cggcggccag ctatgccagc aaaatcatca
    45961 agcgtgcagg tggttttact gcacaagtcc atcagcgcca gatgattggg caggtagccc
    46021 tttatcaagt tgctaatcct aaactagcgc aagagaagat tgccagcaag aaagcggagc
    46081 tcttggagct tgccaatcaa gcctatcctt ctatcgttaa acgtgggggt ggggcgagtg
    46141 acctgcatgt cgagcagata aaaggtgaac cagactttct cgttgtttat attcatgttg
    46201 atacccagga agccatgggt gccaatatgc tcaacaccat gctggaagcc ttgaaaccag
    46261 tcttagaaga actcagtcag ggacagagtc tcatgggaat cctgtccaac tacgcgaccg
    46321 attctctggt gactgcaagc tgtcgcatgg cctttcgcta cttgagccgc caaaaggatc
    46381 aaggacgaga gattgcggag aaaattgcat tggctagtca gtttgcgcag gctgatcctt
    46441 accgagctgc tactcataat aaaggaattt ttaatggtat tgatgcgatt ttgattgcca
    46501 ctggtaatga ctggcgtgcc atcgaagctg gggcccatgc ctttgccagt cgagatggac
    46561 gctatcaagg tcttagctgc tggacgctgg accttgaaag agaagaattg gtcggtgaga
    46621 tgaccctgcc catgcctgta gcgactaagg gtggctctat cggcctcaac ccacgtgtag
    46681 ctctcagtca tgatctacta ggaaatcctt ctgccagaga attagcccag attatcgtgt
    46741 ccatcggtct tgctcaaaat tttgcagccc tcaaagcctt ggtaagtacg ggcatccagc
    46801 aaggccacat gaaactacag gccaaatccc tagctctcct agctggggct agtgaatctg
    46861 aagttgctcc cctagtagag cgcctcatct cagataaaac ctttaaccta gagacagccc
    46921 agcgctatct cgaaaattta agatcataaa aactcagacg aatcggtctg agttttcttg
    46981 tgtttaaata ctttttcctg gtaatagcgt aactggtaag aagtaaccag ttgtggcgac
    47041 ttccttgcct tcaatctttt gcaagagaag atcaatagtg agacaagcaa tctcttccaa
    47101 aggttgcttg atagtagcca attgagggta gtaattttcg ataaagtagg tcccatcata
    47161 gccgatgacc ttgagctctt ttgggacaga aatgcccaat tcttgagcga ttttaatgac
    47221 cagaatagct gtcaaatcat ccgaagcaaa aatggcatct ggtttttccc gggtcaagat
    47281 attcttgatt tccatttctt ttctgacggg agaaaagtca ctggaaacat tgataatagg
    47341 agcttttggg agtacggatg caaaaccagc gtggcgcagt ccggttggcg aattggaatt
    47401 gtcattccct gtaatcatga tgatagactg ggcacctgtc ttgaccaagg tttgggcagc
    47461 aagaacccca ccagcatagt tgtcagagga gacgacaggg atgtctggcg ataggtttcg
    47521 gtcaaaggaa ataatcggcg ctgtcacacg attgtagtct tcgattccta ggttgtgact
    47581 accagaaatg atgccgtcca cctgattggc ttccaacatt tcgatgtatt cgcgttcctt
    47641 ctcagaatca tgttcactgt tgcagatgat ggtcttgtaa ccatttttga agagttggtg
    47701 ttccaattta tcaatcaatt ctgcatagaa aacattggaa atattgggga aaatcaagcc
    47761 gattaactta gctgattttc cttgcagact acgagccagg ttgttgggtt tatagcccaa
    47821 ttctcgcatg gcttcattga ctttttggat ggttttctca gatagatacc cttttttatt
    47881 gataacccga gaaacggtag taggactgac gcctgcaagt ttggcgacat cagttagttt
    47941 tgcgaccata atctaattca tagtaagttc cagttgggtt tccagatttg atcaggatac
    48001 cattttggtc cgcatgtggg aagacacgac cagaaaatac tttttctcct ttattgatga
    48061 aaatttcaaa gacagagtta tcgatgaaga ttgtagcagt agtagcctga ttctcgatag
    48121 ggcaagaacg agttgtccca aattcttggg catactgttc tccagcctgg ctacgatcca
    48181 ctgtcacttg actgtttaca agatcaaagt tgattgaaag tcccttacct tctttatcag
    48241 caagtaagac aatctcgctc tggctattag cttccaagtt gagttcaagt tcgtaagtgt
    48301 tcttggtttg ggaacggttt gagaaggctt cttcagaagc acgaaggtcc ttaatagcag
    48361 cgactggata ctggtagagc ttgtcgtctt tgatagtgag ttccttgacc aaagagaagg
    48421 ttccttggtg gtcaaaacgg tcagatgggt aagaaacatc tggcaaacca agccagctaa
    48481 ctgctagaac acgcccatca ggagcgttga aggcttgagt tgcataggct tcgaaaccgt
    48541 aatccatgtt ttgaagttga gacacatcta ccattttggc atttttaggg tcaaaggaag
    48601 ccccaatctt atacatattt ggaaagatat tatcgtagtc tagaactttc ttatccaatc
    48661 cttgtggaca gtagagaagg acaggctgtt cctctacaaa gaccagatta ggacattcca
    48721 tcatgtaggc agtacggtcg ttagcaaagt caaggtcgcc aactgcttgc cagtttgtgt
    48781 agtcgttatt gatagccttg tagagacgga cgaagccttt tttctccaag tcctgtccac
    48841 cgacgacagc atagtattga cctttaaagt taaaaatttg tggatcgcgg aagtggtcag
    48901 tagagtctgc tggctggtca atcaagatct tgtcaatctt tgtaatctta ccctccttgt
    48961 ccatcaaagc accgatctgg tatgggtgac ggatccagtt ttcatcgcga acatttcctg
    49021 tataaaatag gaataagtta tcgccaaatt tcatggcaga accagagtag gcaccgtggc
    49081 tatctaatgg agtatctggt aaaactttga ttccagtttc tttaaagtga accaaatcat
    49141 cactttctag ctgtgcccaa gatttcaaac cgtgggctgc accaaaagga aaattctggt
    49201 aaaagaggat ccacttgcca tcaaagtaag aaaagccatt tgggtcgttg agaagtcctg
    49261 tttttggctc aacatggtaa tgagtatgcc atggagattg tgccatattt tcctttatat
    49321 gttgaatttc ttcttgcgtc caatcttgat aaagtctgta acgacgctca gttgtccatt
    49381 ccattcattc ctccaaaaat cttatcactt ttaatagtaa ctgttttcga taaaaaatgc
    49441 aagcctttta tattaaaaaa gaggaaaaac tgtcaaacga ttatcataaa ataaatacag
    49501 gaaatcaatt aaatttttac gaaaatgtga aagataatga aataaaagac tttttaacca
    49561 aggtttcaaa cttatttttc aaggaattcc tgatgaaaca gtcaaaaaca atcaatctaa
    49621 agcttgctca ctaagtggat agaatatttt ttctgcaaaa cgcttgacat atttttaaaa
    49681 catgataaaa taatagtcgt aagggcgaat aaaatcgctt tcaaacaaga acaaaatgtt
    49741 atataaggag atttttgcaa atgaacaatc aggaaattgc aaaaaaagtc atcgatgcct
    49801 tgggcggacg tgaaaatgtc aatagtgttg cccactgtgc gactcgtcta cgtgtcatgg
    49861 tcaaagatga agagaaaatc aataaagaag tgattgagaa cttggaaaaa gttcaaggtg
    49921 ctttctttaa ctcagggcaa taccaaatta tctttggtac aggtacagtt aacaaaatgt
    49981 acgatgaagt tgttgtactt ggcttaccaa catcatctaa ggatgacatg aaagcagaag
    50041 ttgctaaaca agggaactgg ttccaacgtg ctatccgtac tttcggtgat gttttcgttc
    50101 caatcatccc agttatcgta gcgacaggtc tctttatggg tgtgcgtggt cttttcaacg
    50161 ctcttgaaat gccacttcca ggtgactttg caacttacac acaaatcttg acagatacag
    50221 ccttcatcat cttgccaggt ttggttgtgt ggtcaacctt ccgtgtattt ggtggaaatc
    50281 ctgccgttgg tatcgttctt ggtatgatgc ttgtctctgg ctcacttcca aacgcttggg
    50341 cagttgctca aggtggtgaa gtaacagcga tgaacttctt tggtttcatc cctgttgttg
    50401 gtttgcaagg ttccgttctt ccagccttca tcatcggggt tgtcggagct aaatttgaaa
    50461 aagctgtccg caaggttgtt ccagatgtca ttgacctctt ggtaacacca ttcgtgacac
    50521 ttttggtcat gtctatcctt ggactctttg tcattggacc agttttccac gttgttgaaa
    50581 actacatcct tattgctaca aaagcgattc ttagcatgcc atttggtctt ggtggtttct
    50641 tgattggtgg ggttcaccaa ttgatcgtcg tgtcaggtgt gcaccacatc ttcaacttgc
    50701 ttgaagtgca attacttgct gctgaccatg ctaacccatt caacgctatc atcacagctg
    50761 ctatgacagc tcaaggtgct gctactgttg cagttggtgt taaaacaaaa aatccaaaac
    50821 tgaaaacact tgctttcccg gctgctcttt ctgcctttct aggtattaca gagcctgcta
    50881 tcttcggggt gaacttgcgc ttccgtaaac cattcttcct ttcattgatt gctggtgcaa
    50941 tcggtggtgg attggcttct atccttggac ttgctggtac tggtaatggt atcaccatca
    51001 tccctggtac aatgctttat gttggtaacg gacaacttcc acaatacctt cttatggtag
    51061 ctgtatcatt tgcccttggt tttgctctta cttacatgtt tggttacgaa gatgaagtag
    51121 acgcaactgc agctgcaaaa caagctgaag tggctgaaga aaaagaagaa gttgcgccag
    51181 cagctcttca aaatgaaaca cttgtaactc ctatcgtcgg tgatgttgtc gctcttgctg
    51241 atgtcaatga cccagtcttc tcaagtggag ctatgggaca aggtatcgct gtgaaaccaa
    51301 gccaaggcgt ggtctatgca ccagctgatg ctgaagtttc aattgccttt ccaacagggc
    51361 acgcttttgg tttgaaaaca agaaatggtg ctgaagtttt gattcacgtt ggtattgaca
    51421 ctgtatctat gaacggtgac ggttttgaag caaaagtttc tcaaggtaat aaggtgaaag
    51481 ctggcgatgt tcttggaaca tttgactcaa acaaaatcgc tgcagctgga cttgatgata
    51541 caacaatggt tatcgttaca aatacagctg actacgcttc agtagctcca gtcgcaacag
    51601 gttcagttgc gaagggggat gctgtgatcg aagtgaaaat ctaatcaatc ctctctaatg
    51661 tgaaaacgaa caaatgacat gtttgttcgt ttttattaga tagtaagatt tacagaggaa
    51721 aatctaaaaa atagagacat ttagactttc gaagtatgct ataataaaga aaataaaaac
    51781 aagaggttta tcatgacaaa attatatgga agcttggaag cgggcggtac aaagtttgtc
    51841 tgtgctgtcg gtgatgaaaa ctttaacgtt gtagaaaaaa cacaatttcc aacaacaact
    51901 ccaatcgaaa caatcgataa aaccattgag ttcttctcaa aattcgataa ccttgctggt
    51961 cttgcagttg gttcatttgg gccgattgat attgacaaaa actcaaaaac ttatggcttt
    52021 atcacgacga ctccaaaacc aaactgggca aatgtggact tgcttggtgc ccttcgtcgc
    52081 gccctaaacg tgccaatgta cttcacaaca gacgtaaaca gctctgctta cggtgaaatg
    52141 gttgcccgta acaatgctgg tggtcgtatc gaaaacttgg tttactacac aatcggtaca
    52201 ggtatcggtg caggcgtcat ccaacgtggt gagtttatcg gtggtgtggg tcaccctgaa
    52261 atgggtcatt attatgttgc tagacaccca atggatattg aaaaagagtt taagggtgtt
    52321 tgtcctttcc ataagggatg tctagaaggt tatgcagctg gtccaagttt ggaagctcgt
    52381 acaggtgtac gtggggaaac tattgaactc aacaaccctg tttgggatgt tcaagcctac
    52441 tatatcgctc aagctgcggt taatgcgaca gtgactttcc gcccagacgt gattgtcttt
    52501 ggtggagggg tcatggctca acaacatatg ctggaccgtg tccgtgagaa atttacatct
    52561 cttcttaatg gttacctacc agtaccagat gtgcgtgact atatcgtgac gccagcagtc
    52621 gcaggaaatg gttctgccac acttgggaac tttgttcttg caaaagaagt ttcaaaataa
    52681 agcacaaaat ccgcttggga aaccaaacgg attttgtggt tgaaaacaat atttttgagc
    52741 ctttccttaa gtgattacgg acggtagcga ctttcttcga aattccatac ctaaactttg
    52801 agcctagtgt ctcaaagttt ccgaatacct gaaaccatta gatttcaggt gtttctatca
    52861 cggcggaaag gctaggtaag tcctcgcctc actatcgaaa aatatgcatg atttccatac
    52921 caaagtatat ttagtatcaa gctatagtta atctacgctt taaaaatcca cttgggaaac
    52981 caaacggatt ttttacgtgt caaagcattt gccagaaaaa gtcaataata taggtcagac
    53041 cgtaggtata aaccacgagg gtaaagggtt tggtcagaat gatgatggtc atgtagcgct
    53101 tgaaactcat cttggtcagg gcagccagca tacagagaaa gtcagctggg ctaatgggcc
    53161 aaatcatcat aaaaataaag aagcggtcaa aacgattgcc cttatctagc cagccgatgt
    53221 acttgtcgta ggtgcgcttg ctgacgacag actggacaaa ggcagctccg tataggcgca
    53281 ctagataaaa gataatggca cagccaatca cgatgccgat atagttgtag atagtcccga
    53341 tgatgtgccc gtagataaag accccagcca ccgaggtcaa ggcccctgga atgataggga
    53401 cgacagtctg taaaatctgt aaaaagataa agagaggtgg accccagatg cctgcctgct
    53461 ggataaaggc agagagggtt tccttggatt gtaaaatccc agcctgataa gcccaaatac
    53521 agaaaatcaa actcccaacc ccaccgacaa tcgatgagat attgataact cgctgcagaa
    53581 ggggagaaac agctttcatt tgtttatcct gtgacatgta aactcctcat agatagtata
    53641 tttctactat accatatttt ggaggagaaa gggggaatga gtcttttttg ataaggaata
    53701 gaaagtaaat agcccttcga gacttagaat aggtctgtca actaaaggtt atatgcattc
    53761 taggtttcga ataatcgcaa ttccataaat ttaaaagcat tctaagtttc gaatagctta
    53821 tctgagataa ttttgaggca ttcgcgcttt cgaatagtca tttttcctaa agtttagatg
    53881 tattctgaag ctagaaagac taaaatctaa aagtagtaag agtctctctc tgatggacgt
    53941 aatttatggc tagtatgaat cctttgaatt gttagttaat tttaatatta atcagttctg
    54001 aaataattac taaatatagt tagatggtga attaattatt gctaaatttc aagttcaagt
    54061 tagtcatcca gaagtcttct ctgggggact tgtagttcaa gcatttttta ggatagttgt
    54121 taatccactt ttcgatgaat gcgacttcct ttgtagtcgt tttcttagtt ccctgaggta
    54181 accatctatg aatgagtctg ttgtgatttt cattagatcc tatagtgatg tgcataatag
    54241 atatagcaga ttgaaactag aatagtatac atctacttct aaaacattgt tagaaatcaa
    54301 tttgactgtc ctgatcaatt tgtcctgttt ttatttcatt ttactatata atccttagaa
    54361 aacatatggg acaagcggtt gaattctgtt ccgtccatta gtagataaag gattactcct
    54421 tcttgaaatg acagatgaac ttgtttctta taaaaatgtt gtctgaaact attcgccttt
    54481 ttccagaagt tttagaggaa gaaaacttta tgaggaaaaa ggagttactc aaataacaat
    54541 tcaggattaa aaatagacag ttgaggagcg gaaggtataa attaagtttg ctactgtata
    54601 atggatttat cactaatact cttcgaaaat ctcttcaaac cacgtcagct tcgccttgcc
    54661 gtacgtatag ttactgactt cgtcagttct atccacaacc tcaaaacagt gttttgagct
    54721 gacttcgtca gttttatctg caacctcaaa gctgtacttt gagcagccta cggctagctt
    54781 tctagtttgc tctttgcttt tcattgagta taaaagtgct ccaggccata ttttacacag
    54841 caatagtctt ctaaaaatgg acaaaaaaca ttgtaaaggc tatcaaaaag gagtataatg
    54901 agtgcaagaa atttcggagg tgaaagatgc tagaagtaag aagtctagag aaaagttttg
    54961 gatccaagca agttttgttt ggtattgact ttcaagcgcg accaggtcgt attttgggac
    55021 tagtcggaaa aaatggtgct ggaaaaacaa cgattttcca tagtattttg aaattcctag
    55081 aatatcaggg agaaatcggt ctggatggtc aggatattcg tcaggagacc tatgctcgga
    55141 ttggttatct gcctgaagaa cgcagtctca tgcctaaatt gacagttctt gaacaagttc
    55201 gctacttggc gactctaaaa ggcatggatg ccaaagaagt caaagaaaaa ctccctcaat
    55261 ggatgaagag gttggaagtg aaaggaaagc tgacagataa aatcaagagt ctgtcaaaag
    55321 gaaatcagca gaagattcag ctcattatta ctctgattca tgaaccagac ctgattatct
    55381 tggatgagcc ttttagtgga ttggacccag ttaatacaga attgctcaaa caagtcattt
    55441 ttcaggaaaa agagcgcgga gcaaccatta tcttttctga ccatgtcatg accaatgttg
    55501 aggaactttg tgacgatatt ctgatgatcc gagatggccg tgtggtcttg cacggaccag
    55561 ttcaggatgt ccgcaatcaa tacgggaaaa cgcgtctctt tgtttcaagt gaacgaagca
    55621 aggaagaatt ggaaaatctt cctcatgtca aacaggtgag cttgaccaaa caaggcagtt
    55681 ggaaattgat tttggaggat gagagcgctg gaagggaact cttcccaatc ttgactcaag
    55741 gtcaatatat cgcaacattt gaccaacaag cgccaactat cgatgaaatc tttaaactag
    55801 aatcaggagt ggaagtatga gaaatatgtg ggttgtaatc aaggaaacct atcttcgaca
    55861 tgtcgagtca tggagtttct tctttatggt gatttcgccg ttcctctttt taggaatctc
    55921 tgtaggaatt gggcatctcc aaggttcttc tatggctaaa aataataaag tggcagtagt
    55981 gacaacagtg ccatctgtag cagaaggact gaagaatgta aatggtgtta acttcgacta
    56041 taaagatgaa gcaagtgcca aagaagcaat taaagaagaa aaattaaaag gttatttgac
    56101 cattgatcaa gaagatagtg ttctaaaggc agtttatcat ggcgaaacat cgcttgaaaa
    56161 tggaattaaa tttgaggtta caggtatact caatgaactg caaaatcagc ttaatcgttc
    56221 aactgcttcc ttgtctcaag agcaggaaaa acgcttagcg cagacaattc aattcacaga
    56281 aaagattgat gaagtcaagg aaaataaaaa gtttattcaa acaattgcag caggtgcctt
    56341 aggattcttt ctttatatga ttctgattac ctatgcgggt gtaacagctc aggaagttgc
    56401 cagtgaaaaa ggcaccaaaa ttatggaagt cgttttttct agcataaggg caagtcacta
    56461 tttctatgcg cggatgatgg ctctgtttct agtgatttta acgcatattg ggatctatgt
    56521 tgtaggtggt ctggctgccg ttttgctctt taaagatttg ccattcttgg ctcagtctgg
    56581 tattttggtt cacttgggag atgctatctc actgaatacc ttgctcttta ttttgatcag
    56641 tcttttcatg tacgtagtct tggcagcctt cctaggatct atggtttctc gtcctgagga
    56701 ctcagggaaa gccttgtcgc ctttgatgat tttgattatg ggtggttttt ttggagtgac
    56761 agctctaggt gcagctggtg acaatctcct cttgaagatt ggttcttata ttccctttat
    56821 ttcgaccttc tttatgccgt ttcgaacgat taatgactat gcggggggag cagaagcatg
    56881 gatttcactt gctattacag tgatttttgc ggtggtagca acaggattta tcggacgcat
    56941 gtatgctagt ctcgttcttc aaacggatga tttagggatt tggaaaacct ttaaacgtgc
    57001 cttatcttat aaatagaaga gccttgcgaa agcgaggttt ttaaaggtga aaagggtgga
    57061 atcacgaacc taattatgta cacattatgt aaacaggttg cttgaaaact caattgtata
    57121 gtgaactgaa tctggaatag gataatatta cttctaaaac attcttataa attgatttga
    57181 attccaaaat ctcatcgttc cgttcttatt tcattttgcg atatagtgaa aggaaataag
    57241 tcagctcaca aaaaacgcat aatatcaagg atttttaaca cttgatacta tgcgttttct
    57301 aattttaaag actttttgcc tggtttcttt tgttctatga gtatgttaca tatctaggta
    57361 aaaattattt aaagcaaatt aaccttattt ctcaagatgt agtaggttcc gagataaaag
    57421 atagctatga atatgagttc tttaacaatg gctatacctg ctcccatata gaaatggtca
    57481 ttgagtccta ccagtgaatt gacatagaaa ttagaactaa gattgaagaa aagttcaata
    57541 aatccaatga cgatttggat accaatgtag gctgcaacag cgagtgctgt acggtattca
    57601 ttgaaaagct gtccaatgga aatagccagg tagatgcaga ggattcctga aatggtattt
    57661 agtaggaagg atatacctgt aagaaagatc tgagggagat gtgtttctac aaatgtaatc
    57721 acataagaaa gaggaatcca ttctggagct gttaaagcca gaataataac agcacttaga
    57781 gccaatacag cggtgctaat caatgaccag ataaaggcac cgattagttt ggctgtgatg
    57841 atatggtgtt cagaaactgg caaggtcaaa gtcagatagc cttgtcggtc gtagacacta
    57901 cctttgaagc gtttaataat caagaaaatg gttgaaatcg caagtgtaag catcaagcca
    57961 ccaaagactg tggctagaaa aagtagcata gtagcctgac tttcttggta aggtagattt
    58021 ttaaagcctt gtgtctgtat tccgatgagg gcagaaagga ctagcacggc tgcgtagagg
    58081 gctaaatacc acttgttaac atttttaaat tcgtagcgaa ctaaattcca aaacataaat
    58141 aatctccttt gcttaggcct taaattcctg acggaagagt tggtcaatgg attcacctga
    58201 ctcgtagcga atatcatcta catttccttg acggacgact tttccgtctt ttaggaagac
    58261 aatttcatcc aagattggct cgatatcaga aatcaagtgg gtagaaatca aaacggtaga
    58321 agttggtgag tagttgttga taatggtatt gaggatataa gcacgggctg ctggatccac
    58381 cccaccaatg ggttcgtcca aaacatagag acgagcatca cggctcataa ccaaaatcag
    58441 ttgaaccttt tctttgtttc cttttgatag tttcttgaga cgactatttt catcaatgcc
    58501 caggtctgca agtagatgat gagcgcgttc aagattgaaa tctttataga aggtcttgaa
    58561 gtaggttagg gcttctttga ccttcatttg ctcattgaga taggtcgtat caggcaaata
    58621 agctacaacg gccttggttg ctgggcttgg gtccatgtcg ttgatgagga cacgtccttg
    58681 atctggttgt aagaggccat taattagttt aatcagggtt gtttttcctg agccgtttgg
    58741 cccaagaagg ccgacaattt ttccagctgg aatgtcaaga gaaacatttt caagggctgg
    58801 tgttgctcca tatgatttgg atacattttc aaatactagt aatgacatag gcttaaactc
    58861 ctttaatata atcactgact acgcctggta gttcttcttt ttcatagcca aaatgggtca
    58921 tggaggaaac gaagtgttcc aattcttctt ctgataattg tttgcgtgac tgggcgatta
    58981 gctccttatc cttagtcaca aatcgtccag ttgttcgctt gctgtagaca aatccttctc
    59041 gttcaaggtc tgataaggct ctttggatgg tattgggatt gacaccagcc tcgctagcta
    59101 gctccctcac ggttggaagt tgttgattgg gttccagtgt atgggaaaca atctgaagct
    59161 tgattttctc cataatctgt aaatagatgg gttttttgtt gtcaaatgtc caggacatct
    59221 tagtctcctt tctcttatcc ttttgtctta attaaataat acaacaaaac aaaaaacttg
    59281 tcaagcaaaa agaagaattg ttttgggaat cgcttaaaaa atggtataat gaaaagaaaa
    59341 cgataaggag ggaaaggatg cgttgtccaa aatgtggggc taccaagtca agtgttatcg
    59401 atagtcgcca agcagaagaa gggaacacca ttcgtagaag acgtgagtgc gacgaatgcc
    59461 aacaccgttt tacaacctac gaacgagtag aagaaagaac cttagtggtt gttaaaaaag
    59521 atggtacacg ggaacaattc tccagagata aaatctttaa tgggattatc cgctcagccc
    59581 agaaacgtcc tgtgtcaagt gatgaaatca acatggtagt caatcgtatc gaacagaaac
    59641 tccgtggtcg aaatgaaaat gaaattcaaa gtgaggacat tggttcactc gtcatggagg
    59701 agttggctga attggacgag attacctatg tacgttttgc tagtgtctat cgtagtttta
    59761 aggatgtcag tgagttagag agcttgctcc aacaaatcac ccagtcctct aaaaagaaaa
    59821 aggaaagata aatgaagcca attgaccgtt tttcttatct acagaataat cgggtgtcgc
    59881 aagatacctc atctctggta cagtgctacc tcccgattat cggtcaggag gcactgagcc
    59941 tttatcttta tacgattagt ttttgggata atggtagaaa ggaatatctt ttttcaagta
    60001 tcctcaatca tctcaacttt gggatggata gactgataaa atcattgaaa atcttatctg
    60061 cttttaatct cttgactctc tatcaaaagg gggatgttta tcagctagcc ctccatgctc
    60121 ctctatctag tcaagacttc ttgaggcatc ctgtttatcg cagactctta gagaaaaaga
    60181 ttggcgactc tgctgtggag gatttgaaag ttgaaagtgc tgatggtgaa gaaatacctg
    60241 tctcactcaa tcaagtcttt ccagaattgg cagaactagg cagtcaagaa gaccttggtc
    60301 tcaagaagaa agtggctaat gattttgact tggaacattt tcgccagctg atggctcgag
    60361 atggacttcg ttttgcggat gagcagtccg atgtcttaaa cctctttgct attgccgagg
    60421 agaagaaatg gacttggttt gaaacctatc aattggccaa gtcaacagct gtttctcagg
    60481 ttatttcaac caaacgcatg cgtgaaaaaa ttgctcaaaa accagtttcc tctgacttta
    60541 gtcttaagga aacaaccatt atcaaagaag ccaaaagtaa aactgccctg cagttcttgg
    60601 cagaaatcaa gcaaacacgc aagggaacca ttacccaaac agaaagagaa ctcttgcaac
    60661 agatggctgg cttgggctta ctggacgaag tcatcaatat tattctctta ttgaccttta
    60721 ataaggtgga ttcggcaaat atcaatgaga aatatgccat gaaggtagcc aatgactatg
    60781 cctatcaaaa gattcattcg gcagaagagg ccgttttacg aattcgtgag cgagggcaga
    60841 aagcaaaaac acaaaaacag aatcagactg ccccagcaaa aaccaatatt cctaaatgga
    60901 gtaatcctga atataaaaat acgtcatccg ctgaggaatt agaagagatg gaacgccaaa
    60961 ccctagaatt attagcaaaa ttagataacg gaggtgatta gatggaaagt gtcggagatg
    61021 tactcaaacg tcaaccaagt cgttttcact atcaagattt agttcagaaa atcatgaagg
    61081 atcctgatgt tgcggccttt gtccagcaag aatccctcaa tcaggacgag ttgaaccgta
    61141 gtatttccaa gtttaaccaa tacatcactg agagagataa attcctccga ggagatacag
    61201 attatattgc caaaggctac aagcctatat tagtcatgaa ccatggctat gcggatgttt
    61261 cttatgaaga aactcctgaa ctaatcgcag ctgaaaaaga agcggctatc aagaaacgtc
    61321 tcaacttaat taattttcca tctagcctga aaaatgtcag ttttttagat gtttatcgtg
    61381 atgatgttca gcgcttaact gttctaaaaa gaatgataga atttgttaac gattacccca
    61441 ataatttgaa aggtctttac ttgtatggag actttggtgt gggtaaaagt ttcatggtgg
    61501 ctgccctagc tcatgattta tcagaaaaac gtggtgtatc atccactctc ctccactatc
    61561 ctagctttgt cattgatgtc aaaaatgcta tcggtgatgg caatgttaag accttagtgg
    61621 atgagattaa gttttctgaa gtcctgattt tagatgatat tggtgccgag caatccaccg
    61681 cttgggtgcg tgatgaaatc ctgcaggtca ttctccaata tcggatgcag gaaaatttac
    61741 cgaccttttt cacctctaac ttcaactttg aagatttgga gaagcatttc gctaaaggga
    61801 aaaatggaaa tgacgaaacc tgggaagcca gacgtgtcat ggaacgcatc cgttatttgg
    61861 ctgaggagac tcgtttagaa ggagtaaacc gtcgatgaca gaaaccatta aattgatgaa
    61921 ggctcatact tcagtgcgca ggtttaaaga gcaagaaatt ccccaagtag acttaaatga
    61981 gattttgaca gcagcccaga tggcatcatc ttggaagaat ttccaatcct actctgtgat
    62041 tgtggtacga agtcaagaga agaaagatgc cttgtatgaa ttggtacctc aagaagccat
    62101 tcgccagtct gctgttttcc ttctctttgt cggagatttg aaccgagcag aaaagggagc
    62161 ccgacttcat accgacacct tccaacccca aggtgtggaa ggtctcttga ttagttcggt
    62221 cgatgcagct cttgctggac aaaacgcctt gttggcagct gaaagcttgg gctatggtgg
    62281 tgtgattatc ggtttggttc gatacaagtc tgaagaagtg gcagagctct ttaacctacc
    62341 tgactacacc tattctgtct ttgggatggc actgggtgtg ccaaatcaac atcatgatgt
    62401 gaaaccgaga ctgccactag agaatgttgt ctttgaggaa gaataccaag aacagtcaac
    62461 tgagacaatc caagcttatg accgtgtgca ggctgactat gctggggggc gtgcgaccac
    62521 aagctggagt cagcgcctag cagaacagtt tggtcaagct gaaccaagct caactagaaa
    62581 aaatcttgaa cagaagaaat tattgtagaa agtgagaaat tatggcccta ccaactattg
    62641 ccattgtagg acgtcccaat gttgggaaat caaccctatt taatcggatc gctggtgagc
    62701 gaatctccat tgtagaagat gtcgaaggag tgacacgtga ccgtatttat gcaacgggtg
    62761 agtggctcaa tcgttctttt agcatgattg atacaggagg aattgatgat gtcgatgctc
    62821 ctttcatgga acaaatcaag catcaggcag aaattgccat ggaagaagca gatgttatcg
    62881 tctttgtcgt gtccggtaag gaaggaatta ctgatgcaga cgaatacgta gctcgtaagc
    62941 tttataagac ccacaaacca gttatcctcg cagtcaacaa ggtggacaac cctgagatga
    63001 gaaatgatat ctatgatttc tatgctctcg gtttgggtga accactgcct atctcatctg
    63061 tccatggaat cggtacaggg gatgtactag atgctatcgt agaaaatctt ccaaatgaat
    63121 atgaggaaga aaatccagat gtcattaagt ttagcctgat tggtcgtcct aacgttggaa
    63181 aatcaagctt gatcaatgct atcttgggcg aagaccgtgt tattgccagt cctgttgctg
    63241 gaacaactcg tgacgctatt gatacccact ttacagatac agatggtcaa gagtttacca
    63301 tgattgatac ggctggtatg cgtaagtctg gtaaggttta tgaaaatact gagaagtact
    63361 ctgtcatgcg tgccatgcgt gctattgacc gttcagatgt ggtcttaatg gtcatcaatg
    63421 cggaagaggg gattcgtgaa tacgacaagc gtatcgctgg atttgctcat gaagctggta
    63481 aagggatgat tatcgtggtc aacaagtggg atacgcttga aaaagataac cacactatga
    63541 aaaactggga agaagatatc cgtgagcagt tccaatacct gccttacgca ccgattatct
    63601 ttgtatcagc tttaaccaag caacgtctcc acaaacttcc tgggatgatt aagcaaatca
    63661 gcgaaagtca aaatacacgt attccatcag ctgtcttgaa cgatgtcatc atggatgcca
    63721 ttgccatcaa cccaacaccg acagacaaag gaaaacgtct caagattttc tatgcgaccc
    63781 aagtggcaac caaaccacca acctttgtta tctttgtcaa cgaagaagaa ctcatgcact
    63841 tttcttacct acgtttcttg gaaaatcaaa tccgcaaggc ctttgttttt gagggaacac
    63901 cgattcatct catcgcaaga aaacgcaaat aaaaaagtag aatctggaat gacagttccg
    63961 gatttttttg atataataaa ataatagaaa acgctatcaa aagaaggagg gggatgtcgg
    64021 tgatggaaca tttgtttaaa ttcttacttt tagcaccgta cttttatttt gataactgga
    64081 ttgaaaaggc caacagaaat agtaagtttt ttccaatttt ttattatttt tactggattt
    64141 acatcccctt ctattctctt tttagccttg cttggacagt tgtttcagtt ctgtttttca
    64201 ataccgtctt gagaaatgtg acagatatca agttatgggg catttggttt ctttttattc
    64261 tgctagctat tggtatgaat tggttaactt attcctgttt caaagaaatg tttcgcttga
    64321 gacaggaact agggaagtct aagggtggaa ggcattgatt tatatcggtt tctatttgta
    64381 ggaggtggct tatggtacct ctaaaatcat ttattacacg ctattccaag gtttatattg
    64441 gtaataacat ttaatagaac gaaactaaag aaaacaattt aaaaaaggag gcttgtgatg
    64501 gaacacttgt ttaaaatgat aatcttatta ccctgttttt actttttcag ctggattgac
    64561 aaggataata gagaaagtaa atttttccca attttttact atttttactg gatttacatc
    64621 accctctatg ctctttttag ccttgcttgg acagtttttt cagttctgtt tttcaatatc
    64681 gtcttgagaa atttgacaga tataaagtta tggggtattt ggctattatt actacttatc
    64741 gcttttgcta gtgactggtt agactatatc tgtttcaaaa aaatgcttga cttgagacgg
    64801 gaactaggga agtctaaagg tgtgcataaa ggaaggtgta ggaactaaaa aatgactgta
    64861 tctatgattt gtttatggag ctatagatac agtcattttt attttgatta tgaaacttga
    64921 gagaaatatt catcttgtat agtggattga atatggaata atacaataca acttataaaa
    64981 cattggtata aaatgcttta gatcccctaa ttga
//
LOCUS       DAVLXH010000006        54680 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00028199
            SAMN33607166-rid17955573.denovo.006, whole genome shotgun sequence.
ACCESSION   DAVLXH010000006 DAVLXH010000000
VERSION     DAVLXH010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607166
            Sequence Read Archive: SRR23725544
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 54680)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 54680)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721421.1
            Genome Coverage       :: 115x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:42:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,210
            CDSs (total)                      :: 2,161
            Genes (coding)                    :: 2,023
            CDSs (with protein)               :: 2,023
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 73 of 138
            Pseudo Genes (incomplete)         :: 60 of 138
            Pseudo Genes (internal stop)      :: 40 of 138
            Pseudo Genes (multiple problems)  :: 31 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..54680
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607166-rid17955573.denovo.006"
                     /strain="AUSMDU00028199"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1349"
     gene            47..835
                     /gene="codY"
                     /locus_tag="VYO11_000410"
     CDS             47..835
                     /gene="codY"
                     /locus_tag="VYO11_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HEV1595017.1"
                     /translation="MAHLLEKTRKITSILKRSEEQLQDELPYNAITRQLADIIHCNAC
                     IINSKGRLLGYFMRYKTNTDRVEQFFQTKIFPDDYVQGANMIYETEANLPVEHDMSIF
                     PVESRDDFPDGLTTIAPIHVSGIRLGSLIIWRNDKKFEDEDLVLVEIASTVVGIQLLN
                     FQREEDEKNIRRRTAVTMAVNTLSYSELRAVSAILGELNGNEGQLTASVIADRIGITR
                     SVIVNALRKLESAGIIESRSLGMKGTYLKVLISDIFEEVKKRDY"
     gene            835..1410
                     /locus_tag="VYO11_000411"
     CDS             835..1410
                     /locus_tag="VYO11_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HEV1595018.1"
                     /translation="MTKALISIDYTEDFVADSGKLTAGAPAQAISDAISKVTRLAFER
                     GDYIFFTIDAHEENDCFHPESKLFPPHNLIGTSGRNLYGDLGIFYQEHGSDSRVFWMD
                     KRHYSAFSGTDLDIRLRERRVSTVILTGVLTDICVLHTAIDAYNLGYDIEIVKPAVAS
                     IWPENHQFALGHFKNTLGAKLVDENLNELSE"
     gene            1492..1577
                     /locus_tag="VYO11_000412"
     tRNA            1492..1577
                     /locus_tag="VYO11_000412"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1526..1528,aa:Leu,seq:aag)
     gene            1860..2990
                     /gene="ugpC"
                     /locus_tag="VYO11_000413"
     CDS             1860..2990
                     /gene="ugpC"
                     /locus_tag="VYO11_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HEV1595019.1"
                     /translation="MVELNLKNIYKKYPNSEHYSVEDFNLNIKDKEFIVFVGPSGCGK
                     STTLRMIAGLEDITEGTASIDGVVVNDVAPKDRDIAMVFQNYALYPHMTVYDNMAFGL
                     KLRKYSKEDINKRVQEAAEILGLKEFLERKPADLSGGQRQRVAMGRAIVRDAKVFLMD
                     EPLSNLDAKLRVSMRAEIAKIHRRIGATTIYVTHDQTEAMTLADRIVIMSATKNPAGT
                     GTIGRVEQIGTPQEVYKNPVNKFVAGFIGSPAMNFINVKLVGSEIVSDGFRLKVPEGA
                     LKVLREKGYEGKELIFGIRPEDVNAEPAFLETFPDCVVKATISVSELLGSESHLYCQV
                     GKDEFVAKVDARDYLQTGATVELGFDLNKAHFFDVETEKTIY"
     gene            complement(3137..3283)
                     /locus_tag="VYO11_000414"
     CDS             complement(3137..3283)
                     /locus_tag="VYO11_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1595020.1"
                     /translation="MEIKEQTRKLAVSCSKYSFEVADKTDEVSNHTYGKATLTWFEEI
                     FEEY"
     gene            3491..4249
                     /locus_tag="VYO11_000415"
     CDS             3491..4249
                     /locus_tag="VYO11_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001848902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HEV1595021.1"
                     /translation="MSEAGHKFLAKLGKKRLRPGGKRATDWLIAEGGFSKEKRILEVA
                     CNRGTTAIELAQRFGCKITAVDMDAQALEVAKKSAGTAGVAHLISFERANAMKLPYQD
                     ASFDIVINEAMLTMQADQAKKKCVMEYLRVLKPGGLLLTHDVLLKEAKESIRQELSQA
                     IHVNVGPLTQDGWEQVMIESGYCDVKALTGEMTLMKLSGMIYDEGLLGTLKICVNACK
                     KENRKQFLTMYKMFAKNKQKLGFIAMASYKSSKR"
     gene            4337..4849
                     /locus_tag="VYO11_000416"
     CDS             4337..4849
                     /locus_tag="VYO11_000416"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001049318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HEV1595022.1"
                     /translation="MNLKDYIATIENYPKEGITFRDISPLMADGNAYSYAVREIVQYA
                     TDKKVDMIVGPEARGFIVGCPVAFELGIGFAPVRKPGKLPREVISADYEKEYGVDTLT
                     MHADAIKPGQRVLIVDDLLATGGTVKATIEMIEKLGGVMAGCAFLVELDELNGREKIG
                     DYDYKVLMHY"
     gene            5031..5975
                     /locus_tag="VYO11_000417"
     CDS             5031..5975
                     /locus_tag="VYO11_000417"
                     /EC_number="2.3.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine O-succinyltransferase"
                     /protein_id="HEV1595023.1"
                     /translation="MPIRIDKKLPAVEILRTENIFVMDDQRAAHQDIRPLKILILNLM
                     PQKMVTETQLLRHLANTPLQLDIDFLYMESHRSKTTRSEHMETFYKTFPEVKDEYFDG
                     MIITGAPVEHLPFEEVDYWEEFRQMLEWSKTHVYSTLHICWGAQAGLYLRYGVEKYQM
                     DSKLSGIYPQDTLKEGHLLFRGFDDSYVSPHSRHTEISKEEVLNKTNLEILSEGPQVG
                     VSILASRDLREIYSFGHLEYDRDTLAKEYFRDRDAGFDPHIPENYFKDDDVNQVPCLC
                     WSSSAALFFSNWVNHAVYQETPFDWRKIEDDASAYGYL"
     gene            5984..6661
                     /locus_tag="VYO11_000418"
     CDS             5984..6661
                     /locus_tag="VYO11_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain-containing protein"
                     /protein_id="HEV1595024.1"
                     /translation="MTYLDAFKSGALVLPSALLLHFKELFPSSDDFLVWQFFYLQNTT
                     GLEEMSPSQIAERIGKEISDVNQSISNLTERGLLQYRTIELNGEIELLFDASLALERL
                     DDLFGAVHSSSDQLTPQNQLKDLVETFQQELGRLLTPFEIEDLTKTLKEDGTSADLIK
                     EALREAVLNGKPNWKYIQAILRNWRHEGIKSVAQIEAKRAEREASNPQLTQVSADFIN
                     AMDLWKD"
     gene            6759..7517
                     /locus_tag="VYO11_000419"
     CDS             6759..7517
                     /locus_tag="VYO11_000419"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000087908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HEV1595025.1"
                     /translation="MSRKPFIAGNWKMNKNPEEAKAFVEAVASKLPSSDLVEAGIAAP
                     ALDLTTVLAVAKGSNLKVAAQNCYFENAGAFTGETSPQVLKEIGTDYVVIGHSERRDY
                     FHETDEDINKKAKAIFANGMLPIICCGESLETYEAGKAAEFVGAQVSAALAGLTAEQV
                     AASVIAYEPIWAIGTGKSASQDDAQKMCKVVRDVVAADFGQEVADKVRVQYGGSVKPE
                     NVASYMACPDVDGALVGGASLEAESFLALLDFVK"
     gene            7555..9059
                     /gene="lytC"
                     /locus_tag="VYO11_000420"
                     /pseudo
     CDS             7555..9059
                     /gene="lytC"
                     /locus_tag="VYO11_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_078138769.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase LytC"
     gene            9556..10074
                     /locus_tag="VYO11_000421"
     CDS             9556..10074
                     /locus_tag="VYO11_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HEV1595026.1"
                     /translation="MVELKKEAVKDVTSLTKAAPVALAKTKEVLNQAVADLYVAHVAL
                     HQVHWYMRGRGFLVWHPKMDEYMEALDGQLDEISERLITLGGSPFSTLTEFLQNSEIE
                     EEAGEYRNVEESLERVLAIYRYLSELFQKGLDVTDEEGDDVTNGIFTDAKTETDKTIW
                     MLAAELGQAPGL"
     gene            10205..10711
                     /locus_tag="VYO11_000422"
     CDS             10205..10711
                     /locus_tag="VYO11_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HEV1595027.1"
                     /translation="MTKKIVAIWAQDEEGVIGKDNRLPWHLPAELQHFKETTLNHAIL
                     MGRVTFDGMGRRLLPKRETLILTRNPEEKIDGVATFHDIQSVLDWYQGQDKNLYILGG
                     KQIFQAFEPYLDEVIVTQIHARVEGDTYFPEEFDLSLFETVSSKFYAKDEKNPYDFTI
                     QYRKRKEV"
     gene            10711..10881
                     /locus_tag="VYO11_000423"
     CDS             10711..10881
                     /locus_tag="VYO11_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000442275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1595028.1"
                     /translation="MERSLFGLFTAFLCFICFLAGAQAFRKKRYGLSILLWLNAFTNL
                     VNSIHAFYMTLF"
     gene            10913..12145
                     /gene="clpX"
                     /locus_tag="VYO11_000424"
     CDS             10913..12145
                     /gene="clpX"
                     /locus_tag="VYO11_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002874765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HEV1595029.1"
                     /translation="MSTNRKNDMMVYCSFCGKNQEEVQKIIAGNNAFICNECVELAQE
                     IIREELVEEVLADLSEVPKPIELLHILNHYVIGQDRAKRALAVAVYNHYKRINFHDTR
                     EESEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
                     ILLKLLQVADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGT
                     VASVPPQGGRKHPQQEMIQVDTKNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNNKAI
                     DENSSYMQEIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVRILKEPRNALVKQYQ
                     TLLSYDDVELEFDDEALQEIANKAIERKTGARGLRSIIEETMLDVMFEVPSQENVKLV
                     RITKETVDGTDKPILETA"
     gene            12154..12741
                     /locus_tag="VYO11_000425"
     CDS             12154..12741
                     /locus_tag="VYO11_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002915299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HEV1595030.1"
                     /translation="MELNTHNAEILLSAANKSHYPQDELPEIALAGRSNVGKSSFINT
                     MLNRKNLARTSGKPGKTQLLNFFNIDDKMRFVDVPGYGYARVSKKEREKWGCMIEEYL
                     TTRENLRAVVSLVDLRHDPSADDVQMYEFLKYYEIPVIIVATKADKIPRGKWNKHESA
                     IKKKLNFDPSDDFILFSSVSKAGMDEVWDAILEKL"
     gene            12752..13132
                     /locus_tag="VYO11_000426"
     CDS             12752..13132
                     /locus_tag="VYO11_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HEV1595031.1"
                     /translation="MAKTIHTDKAPKAIGPYVQGKIVGNLLFASGQVPLSPETGEIVG
                     ENIQEQTEQVLKNIGAILAEAGTDFDHVVKTTCFLSDMNDFVPFNEVYQTAFKEEFPA
                     RSAVEVARLPRDVKVEIEVIAEIG"
     gene            13184..14074
                     /gene="rapZ"
                     /locus_tag="VYO11_000427"
     CDS             13184..14074
                     /gene="rapZ"
                     /locus_tag="VYO11_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HEV1595032.1"
                     /translation="MTKKQLHLVIVTGMSGAGKTVAIQSFEDLGYFTIDNMPPALLPK
                     FLQLVEIKEDNPKLALVVDMRSRSFFSEIQAVLDELENQDGLDFKILFLDAADKELVA
                     RYKETRRSHPLAADGRILDGIKLERELLAPLKNMSQNVVDTTELTPRELRKTLAEQFS
                     DQEQAQSFRIEVMSFGFKYGIPIDADLVFDVRFLPNPYYLPELRNQTGVDEPVYDYVM
                     NHPESEDFYQHLLALIEPILPSYQKEGKSVLTIAMGCTGGQHRSVAFAKCLAQDLSKN
                     WSVNEGHRDKDRRKETVNRS"
     gene            14071..15048
                     /locus_tag="VYO11_000428"
     CDS             14071..15048
                     /locus_tag="VYO11_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HEV1595033.1"
                     /translation="MRKPKITVIGGGTGIPVILKSLREKDVEIAAIVTVADDGGSSGE
                     LRKNMQQLTPPGDLRNVLVAMSDMPKFYEKVFQYRFSEDAGAFAGHPLGNLIIAGLSE
                     MQGSTYNAMQLLSKFFHTTGKIYPSSDHPLTLHAVFQDGTEVVGESHIVDHRGIVDNV
                     YVTNALNDDTPLASRRVVQTILESDMIVLGPGSLFTSILPNIVIKEIGRALLETKAEI
                     AYVCNIMTQRGETEHFTDSDHVEVLHRHLGRPFIDTVLVNIEKVPQEYMNSNRFDEYL
                     VQVEHDFVGLCKQVSRVISSNFLRLENGGAFHDGDLIVDELMRIIQVKK"
     gene            15045..15956
                     /gene="whiA"
                     /locus_tag="VYO11_000429"
     CDS             15045..15956
                     /gene="whiA"
                     /locus_tag="VYO11_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HEV1595034.1"
                     /translation="MSFTVAVKEEILGQHHLSWHELSAIIKMSGSIGLSTSGLTLSVV
                     TENAKLARHLYESFLHFYEIKSEIRHHQRSNLRKNRVYTVFTDEKVQDLLSDLHLADS
                     FFGLETGIDEAILSDEEAGRAYLCGAFLANGSIRDPESGKYQLEISSVYLDHAQGIAS
                     LLQQFLLDAKVLERKKGAVTYLQRAEDIMDFLIVIGAMQARDDFERVKILRETRNDLN
                     RANNAETANIARTVSASMKTINNISKIKDIMGLENLPVDLQEVAQLRIQHPDYSIQQL
                     ADSLSTPLTKSGVNHRLRKINKIADEL"
     gene            complement(16044..17171)
                     /locus_tag="VYO11_000430"
     CDS             complement(16044..17171)
                     /locus_tag="VYO11_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000266845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEV1595035.1"
                     /translation="MWMEELPNGKYKFFERYKDPYTEKLKKVSVTMEKKTPQARNQAA
                     ILLQEKINKKLSTKQVESITFEEIYNLFYKSWAQTVKESTKHNCKSVDKKMKEVIPSD
                     TILANLDRRFLQEAIEKIIESNGYITAKKVRHRLRGIFNYAVQYSYIENNEVDYTTIP
                     QKPKTLEELEKKRNNFLTMQEIKALVDVLNRREYHQKYADMVLVLTLTGMRYGELTAL
                     QLKNIDFENNKIEITGNFDSVNKIKTLPKTTNSIRTIKVSESVIEAIQRQIVRLSERF
                     QPLSSDDYIFCFEKWNQPTTIACFIQILKKYGKQAKIEKNLSSHIFRHSHISFLAESG
                     LPIKSIMDRVGHSNAKMTLEIYSHTTEDMEDKLVNKLDTIF"
     gene            complement(17313..17693)
                     /locus_tag="VYO11_000431"
     CDS             complement(17313..17693)
                     /locus_tag="VYO11_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HEV1595036.1"
                     /translation="MTIEELVDSHGVTLAYFDNELWQRPGVYIKEISIIFINRELSEN
                     AKKRVIYHELGHLEHSTALYKNNHTRCENEANRHMIHKLLEEELALSDDHQSFNYIQF
                     MQKHELRTVTDELMVIDEYYELIG"
     gene            complement(17714..18076)
                     /locus_tag="VYO11_000432"
     CDS             complement(17714..18076)
                     /locus_tag="VYO11_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001823580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1595037.1"
                     /translation="MLSEENIMSQDTYSKSEIDLKLDKINSDTQHGFEKIDLKVDQLR
                     QEMRSGFEKIDLKFEQVDLKFDNFEKRVETMFLTQENKRLEEQAKSKKEFMYWFIGLL
                     VSTLLGILAIIVTILTTK"
     gene            complement(18197..18619)
                     /locus_tag="VYO11_000433"
     CDS             complement(18197..18619)
                     /locus_tag="VYO11_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1595038.1"
                     /translation="MTNIPMKKNPFREKMTAISIVNPETAQLLGTITNFDMFPGSTSL
                     VAFLDFFNLRPETDYILSLTAHFPNGTSYPVHATRINIARQEFVLLEDGFGMATGNFS
                     FNFTIEKPSDFYFFFVLMDENGQEVDTAYSYHHFGKWG"
     gene            complement(18621..18974)
                     /locus_tag="VYO11_000434"
     CDS             complement(18621..18974)
                     /locus_tag="VYO11_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000484457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1595039.1"
                     /translation="MFSLFEKIKELCQKRGISINSLEETLGYSRNTIYSMKSKKPNAE
                     RLQEIADYFNVSTDYLLGRTDNPAIAGDDTIAGYTSDDLRKMAENAKTFDGKPLTEED
                     IDAIQNIIEIYLRGR"
     gene            complement(19391..19630)
                     /locus_tag="VYO11_000435"
     CDS             complement(19391..19630)
                     /locus_tag="VYO11_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000142894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1595040.1"
                     /translation="MTFKEYLLKASKRDIYDDGKDFDFETIFAREILRYAHDSELETK
                     TGFFRHLEIMNADSWFVELARSIYQDFEKSISDSH"
     gene            19695..19886
                     /locus_tag="VYO11_000436"
     CDS             19695..19886
                     /locus_tag="VYO11_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001112859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEV1595041.1"
                     /translation="MPDIANGRERVIAFLKEKGIKKATLAVAYGFKRQEVTNILSGTT
                     KGPRANSFILQVIEDYGIE"
     gene            complement(20000..20221)
                     /locus_tag="VYO11_000437"
     CDS             complement(20000..20221)
                     /locus_tag="VYO11_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000041097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1595042.1"
                     /translation="MSKLTKEDVLQVSQDIINDAIPVIKDMLDEVFEKYPIDIEIREA
                     IFYSVLVAHKLSTETTVSLLTQLVNAQEN"
     gene            20339..20482
                     /locus_tag="VYO11_000438"
     CDS             20339..20482
                     /locus_tag="VYO11_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000389591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1595043.1"
                     /translation="MEDKIIELADYFISESTTYREAKIACEKLLKQVSHEIELRAMES
                     RTV"
     gene            20562..20834
                     /locus_tag="VYO11_000439"
     CDS             20562..20834
                     /locus_tag="VYO11_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1595044.1"
                     /translation="MEAVEIVRIKDVIIEKVSANDEELKRIFGCSKRQAGERRREMQK
                     LPSQQKHLLDSGQLVTIKGFYEYLQYRGTKAWKKEMETSKKMRSAG"
     gene            20831..21025
                     /locus_tag="VYO11_000440"
     CDS             20831..21025
                     /locus_tag="VYO11_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1595045.1"
                     /translation="MNLLSRIKNYFSEEVKETNLDWKEVALDLNQSLIETQEKLQEAN
                     QEIADLKKIVAIYKEKEKEK"
     gene            21022..21213
                     /locus_tag="VYO11_000441"
     CDS             21022..21213
                     /locus_tag="VYO11_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000970850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1595046.1"
                     /translation="MMEYIYLVIIVGIGLWSLVNKLDDHAEMKQKERQLIANNVARMN
                     LRNSDKQFTYDVEPPEGLK"
     gene            21225..21566
                     /locus_tag="VYO11_000442"
     CDS             21225..21566
                     /locus_tag="VYO11_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1595047.1"
                     /translation="MTQAEQIREYYREHPAASCDEVAEVVGTTKSNVSANLAKDIKAG
                     RCVRLEDKSYDYSPYYNHTQALTELVDWKNDTRREWVDMLTRAAEKETVSNVMRLLIK
                     EANKLMKEVTK"
     gene            21567..21797
                     /locus_tag="VYO11_000443"
     CDS             21567..21797
                     /locus_tag="VYO11_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000252078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1595048.1"
                     /translation="MVRNKLTDLTNTLFAQLETLDDRDLTADELKTELQRSKQMVAIS
                     GQILQAGQLALDAEKFKDKVGEVNAPIALLEG"
     gene            21811..22533
                     /locus_tag="VYO11_000444"
     CDS             21811..22533
                     /locus_tag="VYO11_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000544345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HEV1595049.1"
                     /translation="MHEICPGRLTPEVTRLLNEKFGTTYTKTQIGEVRRRLGLPVGKV
                     YQGKLLTKEQHDYLVSIQKNKISRDVANEMNLKFGLSLTEKQIKSYRRNNNLHSGFTG
                     RFEKGQTPHNKGKKYPNMPKNSGQFKKGNRPPNYVPVGTINYTTDGYPKEKIGEPNQW
                     VLKHRKVWEEHHGPIPKGHSIVFLDGDKTNYDISNLACLSKNEIARMNQNHLFTSNAD
                     LTKSGIELTKLTNKIREVEKNG"
     gene            22526..23008
                     /locus_tag="VYO11_000445"
     CDS             22526..23008
                     /locus_tag="VYO11_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siphovirus Gp157 family protein"
                     /protein_id="HEV1595050.1"
                     /translation="MASLYELTGQFLTVYQMDIDDETKTDTLEAIDWQEQFEQKAEGY
                     AHVIKNLEADVAMYKAEEESFKAKKQVAQKKLDYVKDNIMAAMNVTGQTEVKSGALII
                     KIAKNPESVKVNEDDLPKKYFTKKVTLAPDKKTLKELLKSGKKVKGAELVRTEKLVIK
                     "
     gene            23008..23367
                     /locus_tag="VYO11_000446"
     CDS             23008..23367
                     /locus_tag="VYO11_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000422310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1595051.1"
                     /translation="MELMNKTRVTDSLAVVIGPESIEVLVTEGFLFDVAIRFVKVDET
                     NLDQGNEKPVFTPEYKLVTVAKYKEKPIFESEEDIRKFEKQAKEVKSLFAFAKVNKQN
                     WFNTALYPGVLTEKVGV"
     gene            23367..23852
                     /locus_tag="VYO11_000447"
     CDS             23367..23852
                     /locus_tag="VYO11_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000696057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1595052.1"
                     /translation="MKILAIDPSSNKIETSTTGVVLLDNARLVDSWVVSYGMRGFADW
                     FHEIGTNLEFDVVIVEEFKARDNDKSKDNSVAETIAYIQLCYPGAILQFNAGYKSDIP
                     NDLLKILDLWKFEKSHHQDIRAAARLGLFWAMRNDIEEVVHDIGKVVSEYHNNAKKVA
                     S"
     gene            23815..25008
                     /locus_tag="VYO11_000448"
     CDS             23815..25008
                     /locus_tag="VYO11_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III restriction endonuclease subunit R"
                     /protein_id="HEV1595053.1"
                     /translation="MSITITLRKWQAEAIKRSEHLSNGIFLEALGGRGKTICALAISK
                     HKNAKKIIITNNRLAILNGWIDAVKFMNFDKDVEIIIQTDRYLQNQVKKGHKLDCDVL
                     IVDEWQNMSSDKQVALYRKIKRKYTIGLSATPIRKKGQNFYPLEKTVFGWATPNNKFD
                     WQKTHGKMVYDPFSYSKEKWEDFRNYESYISNLPNFFRWEDIEKIENAVENNGFEIKF
                     YQKRVASGNPEKLAEFRKLNLVTVDGKTAMAKQSFGRKTFERYLNQTGVAVDFPKLKP
                     VNADTPLMLQLDGLIERAPHDMLIVSKSKQIVNVISERHPEIGIWTGDIQEGLYKKFV
                     VATSQVLGVGVDGLQHKYQTIVVLDPVEEGSGEYDDYRQLLWRITGSRQQHDVNVIEF
                     YYKES"
     gene            25027..25344
                     /locus_tag="VYO11_000449"
     CDS             25027..25344
                     /locus_tag="VYO11_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001044593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1595054.1"
                     /translation="MNKTTEMIVFRSRKTGEFLNSYKDRSSLAFAADFCSLEYCLKLP
                     RKKYEDNKKTYKALAAAFDCEIVAVEAEYKLTYPNGSEVEPIKRDRSSIEDMIKDIIG
                     GVL"
     gene            25344..26171
                     /locus_tag="VYO11_000450"
     CDS             25344..26171
                     /locus_tag="VYO11_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000885998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEV1595055.1"
                     /translation="MAFTLPANKPQVPKDTPRNFFIYGETMSGKSYLANEFPNPIVLN
                     TDGNAEANTVPSIQLINEKDDKGRITNSVIKQLGDILLALQTQKHSYETVVIDVIDDV
                     IEMIKIAVCDELTPVGKPRLKSLSEIPYGKGYDFFNQAITELVIDLKALPMNVIYISR
                     QVSEYDDNGNATKDKPSLKDKYVNLINGNSDLMIHTEKLGNNYNREVDRKRKTYYADQ
                     VDDKAILKILATIRGAVEPAKGKLAPKKEAAKTTKPAKTEKTKEAPKKEVDSDDELF"
     gene            26191..26697
                     /locus_tag="VYO11_000451"
     CDS             26191..26697
                     /locus_tag="VYO11_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000054338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1595056.1"
                     /translation="MSLLDIAKSIKKEGFDPRKDSANGPAPIPAGTYPVVLKKATFNV
                     SDKGWESLGYQFEIRGGDYSGRSEFATFGTLTEWNGKNLDWAVERTMKFFIKALVLAG
                     DSMQGNEEDGKALEEALKRKAVGSYYNLVISVTKGKDGREFRNYDLEEEEAQPLTEAD
                     IDDDDLPF"
     gene            26870..27691
                     /locus_tag="VYO11_000452"
     CDS             26870..27691
                     /locus_tag="VYO11_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001139684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DNA primase/polymerase"
                     /protein_id="HEV1595057.1"
                     /translation="MPSMKEYALQYQKLGFSVIPINPKNKMPLIDFADKPAMTPSEIE
                     NFWDGYPNANIALKTTNFFVIDIDKHGKSNGFESLKKWKHLNLIEPTLQAKTASGGKH
                     LFYFKREDEPITQMIGFLPGVDIKAHENNYVLVAPSATDKGQYEWDLEKSKEGGTMVT
                     PSKDLIQSIKKQYGETHGYKYDGKDGLRDLVRRSQTRDRTQTTDLFETIALGFGDEGG
                     RNDKLAKFVGGLLYRAVDDGVVVQLARLANANSPNPLPEKEMMRTIESMIKKDRR"
     gene            27694..29037
                     /locus_tag="VYO11_000453"
     CDS             27694..29037
                     /locus_tag="VYO11_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000580032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HEV1595058.1"
                     /translation="MIGNVVSIDSQPKMITTAKGDIKANSPSNVLMSFKADDQLSIYL
                     KHNDFSQEHELLKDIKIGNTLFKKGELPSNFDSVVKVYFESVLGVAFSNQAMLDGMET
                     FFSERSYNPVIEYMERATEKWDGRNRIDRMLQVYLGAEDIPLVSKIAQMWLVGAVAKV
                     YDPYVKFDYVLDLVGGQGVGKTSLLQKLGGEWYTDAVTDFSNKDNYDIMLKSLIVNDD
                     EMVASNRMSFAETKAFISKTSLRYRKPYMKRTEEFAKNFILARTTNQTEYLKDKTGER
                     RFLPVMADSKRQKKHPMEIEPETIEQIWGEAVTIYRAGADLMFDENTEDELNIYREQF
                     MYRDEVELQVLEYLDMPVPENWQNWSIQQQHQYTSKYFDNSSDFDPGSKKLDKVSTRE
                     MMYNLFMRNSNDRKLSTKINMIMDNHPDWKKSVFRAGGKSTKGFVRVKDSEKTNR"
     gene            29320..29472
                     /locus_tag="VYO11_000454"
     CDS             29320..29472
                     /locus_tag="VYO11_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000122743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1595059.1"
                     /translation="MSYTVTLYFDNMVDETHLFKKKGDAAKCKAQLESKYRGDRMYKV
                     KMEEME"
     gene            29472..29810
                     /locus_tag="VYO11_000455"
     CDS             29472..29810
                     /locus_tag="VYO11_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1595060.1"
                     /translation="MSYDLEILAKIESGDYICIAEPRYSSPTYNLGKMFRVAMDWDFD
                     QGTIYNVADIFENIKRGITELERQPEKYVQYEPANKWGTINDALYVLRSLRDCILEQD
                     IDTKYLYVRW"
     gene            29961..30275
                     /locus_tag="VYO11_000456"
     CDS             29961..30275
                     /locus_tag="VYO11_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001854688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1595061.1"
                     /translation="MEELKKKVNAVYNWTVEDGKPQPPKQKLPQAVKDRADYFWEMAE
                     DGMTFMGAMECIFADEKPTDYDLGSTKDWLPKSKEFDDWVGYSPSMARVIIAVYLIYR
                     GN"
     gene            30277..30780
                     /locus_tag="VYO11_000457"
     CDS             30277..30780
                     /locus_tag="VYO11_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HEV1595062.1"
                     /translation="MNIKALIKKYEELWNEHSPFYEPVPYTSMVELFLKELKQLDEPQ
                     KVKIPQFVAEYIEFKKKNNFHVYGAMRVIEDHYDKKVPDWFYENNIEKFCLAWLDGYE
                     VEEEKRYLVTLKNRQPLVKSQSGSTLYFSQDITARNYKGTQKELEEAKFGWVFDCEGI
                     DIEEVEE"
     gene            30777..31190
                     /locus_tag="VYO11_000458"
     CDS             30777..31190
                     /locus_tag="VYO11_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000612396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1595063.1"
                     /translation="MIPKFRVWVKIGKRMVFSDDILAIDYENKEIVTQQVYFENGLPD
                     DRDIYCYDFDEIELMQSTGLKDKNGKEVFIGDIVKCTRGCLHEVYLEKEYGGTFIGGM
                     PAVYLKGFGDGYAWTEYEEIIGNIYENLEFLEEKE"
     gene            31187..31558
                     /locus_tag="VYO11_000459"
     CDS             31187..31558
                     /locus_tag="VYO11_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001247150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1595064.1"
                     /translation="MKPCKYPYSGRRKKQETPSPIFSARPIFKEIPIVEEVKVEFEVE
                     ASTGRIYPETIIHLDISGYGNRVHSVYLFPGTLLSVGESIQLKMLFYRRLRNFTTDRF
                     LTFRESDWKFFIRDLVNEFKH"
     gene            31632..32066
                     /locus_tag="VYO11_000460"
     CDS             31632..32066
                     /locus_tag="VYO11_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1492 domain-containing protein"
                     /protein_id="HEV1595065.1"
                     /translation="MNKAKELLDELQNLDEEIQSRIDELANLEASLLSSPKMRMDKVQ
                     GGQKVRLDERYIDIFSMQDPLKEYIKQATAEAIQRRIELSKLIDKMPKPASRTILRMV
                     YIQKANVYDMIEFLRCSKTTFYKKKKDAIRELGVVVDKSELM"
     gene            32163..32253
                     /locus_tag="VYO11_000461"
     tRNA            32163..32253
                     /locus_tag="VYO11_000461"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:32199..32201,aa:Ser,seq:gct)
     gene            33354..33866
                     /locus_tag="VYO11_000462"
     CDS             33354..33866
                     /locus_tag="VYO11_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase small subunit"
                     /protein_id="HEV1595066.1"
                     /translation="MAFFDCLKGGDGKLNERQRRFADEYIISGNAYQSALRAGYSEKY
                     AKARSSELLDNVGISDYIKNRMEELQDEKILTQKQILVMLSEIASGQAKETIVVTTKV
                     AELMTDPVTGKSVKVYNEIPQLVEYPTKNSDRNKALELLGKRYKMWTDKVEADVSGTV
                     VFANESDIPD"
     gene            33844..35142
                     /locus_tag="VYO11_000463"
     CDS             33844..35142
                     /locus_tag="VYO11_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000084419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBSX family phage terminase large subunit"
                     /protein_id="HEV1595067.1"
                     /translation="MSQTYQIKQSDIVIDLPKTVGAGYGQFWRSRNLYRVVKGSRGSK
                     KSKTTALNYVIRLLKYPWANLLVIRRYSNTNKQSTYTDFKWACNVLGVTHLFKFNESL
                     PEITIKATGQKILFRGLDDELKITSITVDVGSLCWAWFEEAYQIETEDKFSTVVESIR
                     GSLDVPDFFKQITVTFNPWNERHWLKRVFFDEETSRADTFATTTTYKCNEWLDGVDIK
                     RYEDLYHTNPRRARIVCDGEWGVAEGLIYENVTVKDFDKDELLRDSANKLCIGLDFGF
                     THDPTALCCSLINDTTKEIYVFDEAYKVGLITKEVAKMIKDKGYHRSQIIADSAESRL
                     IEELRSEHGISRIKESRKGKDSIMAGVSKLQGYTIYVHPDCKNIMDEFYSYCYQRDKE
                     GNWLNKPEDKNNHLMDALRYSLQCIEGGKATVRRRSDYGL"
     gene            35154..36623
                     /locus_tag="VYO11_000464"
     CDS             35154..36623
                     /locus_tag="VYO11_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HEV1595068.1"
                     /translation="MYQYLTYPRDGYDEGSLKKDLIYKLITIHSTEGSHLKKLKSYYL
                     GEHAILEHTRRNVNAPNYKTVANHAKDIADTATGYFMGNPIKYNNTADGDIDELLTAF
                     DGAEIDQVDAQNALNMAIYGRAYEYIYAKEGMTELDSTSIDPENTFMVYDDSIERKPL
                     FAVYYYEVKDDTKDTTKHQAEVFTENLHYHMVLRSTDSGTTQSEEATPHNLGQIPIIE
                     YRNNHFAIGDYEQQISLIDAYNSLMGNRVNDKEQAVESILVLYGTQLADTPEDAKVAM
                     KILSEEGLLELPGDSARAEFLKNTLDESATEILRTALKEDIYTFSHVPNLTDENFAGN
                     TSGVAMEFKLMGLEMITKTKEANYKRGLRQRIAIFAHYLGMKQIALESHSIVPQFSRG
                     LPKNLLEISQIVNNLEGKVTNRQLISLLPFVEDPDAELEALEEEKKKNMEDMPMFNQE
                     NTKPEDEVEDEESGVLGEEESQSDLPADGQGRKAGRPVR"
     gene            36532..38082
                     /locus_tag="VYO11_000465"
     CDS             36532..38082
                     /locus_tag="VYO11_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000795723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
                     /protein_id="HEV1595069.1"
                     /translation="MKNQEYWAKRKANLIYQQMDKAEKQADQFDKVYQEAKTYLDKEV
                     NKIFDKFQRDYGLSQVEARQVLKNMKDKKNLNELRKVLEARPNDPNIQRLLADLDSPA
                     YSFRMKRLERLSDDLDRMRESIYHSEKTGSDAFYSDLMKDSYYKATFDLQQQTGLAYG
                     FSGLPENEIKHLQSFSWVGDGSTYSTNIWKNTGKLTSSIKDELLISLMTGRDTRETAQ
                     AIAERFNVGQNDARRLVRTESAFFHNQMELLNYEEADIEKYIFVAVLDKRTSRICQEH
                     DNQVYDRDKAVPGVNCPPMHPWCRSTTVGYDEDADYSKLKRRARNPETGKVEYVPADM
                     TYKEWYSKYVAKDVKNEIQDYKKSDKTVSRYNTPKLFSDVSNAWDEIGRGGLSKEQLV
                     DLLESEYELGNFSSDIAKLIGVSSAYIDVSSLATSLVRHGQQYSLDEFMLIKEAVQKP
                     YLILDNSERVEKSIISYVKIPNKDKVIMEAVMVPRDEMLVIHFNKVGIRQVKKNEKNM
                     STLYKKGK"
     gene            38233..38406
                     /locus_tag="VYO11_000466"
     CDS             38233..38406
                     /locus_tag="VYO11_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000356388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1595070.1"
                     /translation="MDTARIGITNVEFSGTGENDSATVKLELNIYGADTFSAIELLPK
                     ILTDIHSLSYEVD"
     gene            38551..38763
                     /locus_tag="VYO11_000467"
     CDS             38551..38763
                     /locus_tag="VYO11_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1595071.1"
                     /translation="MEEWKERFKKEYYELKERFQKLDMMIGKYEKGQLEFESKCPIDL
                     LKGQRSTMWNYLRILEQRAKIEEIKL"
     gene            38933..39457
                     /locus_tag="VYO11_000468"
     CDS             38933..39457
                     /locus_tag="VYO11_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001288018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4355 domain-containing protein"
                     /protein_id="HEV1595072.1"
                     /translation="MSEEINATVSTESTETVDTQGNVDSVQEEKHERTFTRAEIGKML
                     SAERSKWEAEQEAKENEAKKLAKMNADEKQKYQLDQREQELADREKAIARKELTAEAK
                     AMLSERDLPVELVNVVDLTSAETVSESITSIQKAWEESVQKGVSERMKGSAPIKNAQT
                     VQQEVTEKWRKDFL"
     gene            39480..40505
                     /locus_tag="VYO11_000469"
     CDS             39480..40505
                     /locus_tag="VYO11_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding protein"
                     /protein_id="HEV1595073.1"
                     /translation="MAFEELNTAESRKKHLGIIEDVLAVNSYSTPLVTSSDAVTLQGR
                     SFTVATGNTTELKDYKRNKDNEFDHVEVEEKVYTLDEEKYWGRFVDQLDERDSNGQVN
                     INYVIARQAAEVVAPYLDELRFGAALGNVSDNVAMGKTAGANNAYNAVLDVSEKLDEL
                     GITKERLLFVTPSFYKAIKSEIVRLPHGDADKKVLGKGYVGELDDYTVYKVPSKFLKG
                     VNALATAPGVVTSPVQVDNTKYNDNIPGRFGELVEQLLYTGAFVLEHFKKYIITIADS
                     KPAAKPSTQGKVVNRAKAWKTGTTYKEGDTVTHADKVYVAVKDISNSSTAPDTDTTNW
                     KEKTGKK"
     gene            40515..40703
                     /locus_tag="VYO11_000470"
     CDS             40515..40703
                     /locus_tag="VYO11_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1595074.1"
                     /translation="MKFKIKQDFYDWESNVKRLAGEELEITEERYAELADNIASNGVA
                     ISDVLEEIFPKPEFLEED"
     gene            40705..41016
                     /locus_tag="VYO11_000471"
     CDS             40705..41016
                     /locus_tag="VYO11_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail adapter protein"
                     /protein_id="HEV1595075.1"
                     /translation="MSIELLKKLTGEEDTQLLMLLQTRATNLILSETNRTSLTPALSL
                     LIPEVAIELHNRSGAEGEHSRTEGGIAVVYGENGLSTDLLQRIRMHRLARVAGHVFEA
                     E"
     gene            40997..41335
                     /locus_tag="VYO11_000472"
     CDS             40997..41335
                     /locus_tag="VYO11_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000478943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1595076.1"
                     /translation="MFLKQSRLKPYPMRRFEKTVTEEGVAKEGYAKEAETVRLELWPA
                     SSKLQSELYGERVNDILNANANKSATIKVKDGVCIDSQTEVTHRVISKKVYTHHQVLE
                     LERVRATRGR"
     gene            41310..41825
                     /locus_tag="VYO11_000473"
     CDS             41310..41825
                     /locus_tag="VYO11_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000015942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HEV1595077.1"
                     /translation="MSGLLGADRLIAKCRRLASKKTGEDIVLRAVHNATIKVVQADAR
                     RLAPARDGELITSIKTRAKMDGDKAIGEVYTNLKYAPYVEFGTGPIGQASHSGISPEV
                     SVTYKSSPWYVHEDQINVGPYHFQKIGEFYKMYGQPAQPYLYPALRDNQERVSKNISN
                     YVRRKIREQIK"
     gene            41822..42190
                     /locus_tag="VYO11_000474"
     CDS             41822..42190
                     /locus_tag="VYO11_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1595078.1"
                     /translation="MINIKPVIYKELQKVADNVTDTYPSDWETFPVVIFLEEQNKPGD
                     WFDDQEQKSSIRYKVDIFDDTSTSELAVKINQIFESLGLRRTDCQDVPDPSHLRHKVM
                     RFEGIVDLHSELVFQFRMEN"
     gene            42193..42606
                     /locus_tag="VYO11_000475"
     CDS             42193..42606
                     /locus_tag="VYO11_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000880678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEV1595079.1"
                     /translation="MLANGITLSYGETKDSYTKLVGLKEVPEFGIELEKVENTTLEDT
                     VKKYEFGIGDIGELEYKFSYNNSSATAPYRVLRKAADDKKKLYFEQAYPDGTKVIFEG
                     QVSVKLGGGGVNAVIDFTLKIALQSNLTFTDGIGG"
     gene            42611..42991
                     /locus_tag="VYO11_000476"
     CDS             42611..42991
                     /locus_tag="VYO11_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001185634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1595080.1"
                     /translation="MALKYTTWKVTDEKELKLRLTSHQAATVEEKIGMNLLKIFMPEA
                     GEEFTLPPLKVMLLLVHGALQQYEHGYSLEDVYDLYDEYVDNGGDQTTFMTEVLMPLF
                     EVSGFTPRGSKDKKTSKKKMTVDK"
     gene            43030..43380
                     /locus_tag="VYO11_000477"
     CDS             43030..43380
                     /locus_tag="VYO11_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000478007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1595081.1"
                     /translation="MFLDIGGKPLDFWDLTVLEIREMIESYNRVKIQERKEKIIDSYR
                     LSQMISNHVSLLLSKDAKAFEFWEYAPELFVEEQQAVEQERQKQALLLHKERMREFAE
                     RHNRKRKEEVNGNS"
     gene            43367..47020
                     /locus_tag="VYO11_000478"
     CDS             43367..47020
                     /locus_tag="VYO11_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000212172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1595082.1"
                     /translation="MATLDELKVMIDAEIAPFRKKMKEVENQVKGTSDQVKNATAKVR
                     EQSSSIGSAFGKLAKFAGFAILGKKLLDVGMYSTQTALEVSASMNQIKRQMGESSQSF
                     LKWVNDNANAMNMGVGEATNYGAVYSNLFSGFIKDTNKLSAYTAKMLQTSAVVAEGSG
                     RTITDVMERIRSGLLGNTEAIEDLGINVNVAMIESTEAFKKFANGQSWQQLDYQTQQQ
                     IRLMAILEQATAKYGDTLSNSVNGRISLFKSLMKDAALNLGNSMLPIINAIMPVLNSF
                     AMVLKNVTAKLAEFIALMFNKKATVKDGVGGAVGDMGNAMKDAAGGAGDLADAVDDAG
                     DSAGGLADNLGDSAKNAKKAAKELLGLLGFDEINILQKPKDDDAGGSGGGGKGGKGKG
                     GGGGPFKDILPEVELTDMDNKFKSIFDGLGDKLKGLFDLFKKGFDAAFRPEGIERIKT
                     ALDQIAKTMGEIATDPRVVNAFNRMAEKIAYALGQVTGSITTIGLGIGVFLAESIANG
                     LGRQKERITRALVALFDNIGNISEAVGNIAQDFSSTFYDVITSTGAVRIGSAIVSTLL
                     SLTSTIVEVGSKLAGSLFKGFEKVVVTSAPKISSVFQSLLDTVAPVFESIERSVNKFG
                     DGLSRVYDEHVAPAINSIANAFNGLIDIIQILWENSWQPFAEFLSGVFGVSIEGISDL
                     LGGGLLATLGLLADAIKLVADGFTVFSDWCKENKEPILALITTWQTINFLSWAEQAGG
                     LAGAFSLLGSKVSLIVGGIKNLGLAIKALTFDKLVSFGETIYLNTLYAKDFVVNSGKT
                     IAQLGKTALELGKSALAWTAHAAKMGLATAAEFAHSVAAGVATAATWAFNAALAVLTS
                     PITWIIAAIAALIAIGVLLYQNWDTVVEFAKTAWQGLCDFISGICRAIGEFFSGLWTK
                     LQEIFEPIGQWFGEKFQQAWDAIVNIFSGIGEWFSGVFQGAWDAIVNIFTPIGSWFGQ
                     RWADVTSALANIGAWFTDIFQKAWTGLTNIFSKLGLWFGERWADVTSVLANVSSWFGN
                     MFTSAYNAVKNAFSSIGGFFSGVWSTVQSIFVNAGQKVGSAVGGAFKSAVNAVLGTIE
                     NVVNGFIGMINGVLGVVRNLPGLGWVGSVSTVSLPRLARGGIVDSPTIAMIGEAGKEA
                     VVPLENTGFIQTLGRVVSSAVVNAMAGISPQGGFSSDGDIVIQIAGHEFGRVAIQEIN
                     KEHERAGQTLLKI"
     gene            47029..47379
                     /locus_tag="VYO11_000479"
     CDS             47029..47379
                     /locus_tag="VYO11_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1595083.1"
                     /translation="MAQLTINGVAVKPPKSFQVGIQDIDGETGRNANGDMVRDRITTK
                     RKLDCEWGMMTQGEISQLLHAVSSKFFEVSYPDPMDGQVTKTFYVGDRTAPSYTFTEK
                     LKPWSGAKFNLVER"
     gene            47384..52759
                     /locus_tag="VYO11_000480"
     CDS             47384..52759
                     /locus_tag="VYO11_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000339662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber domain-containing protein"
                     /protein_id="HEV1595084.1"
                     /translation="MDALTRRQFDRAMFAKERTLAIRVGEYASRDIKEASFEYGYIKG
                     DTYKPGGTCAGSGKITFTSIITTFNKLDTLHPEIGLLVGDTYQWVKMGEYFINDIEID
                     RNRNTTTLELMDGMFKLNREYVTDLHFPAEVREVIQEICLKTGIELANDYFGISAMRY
                     HIEQVPEGKKLSFRDMLSAMTQMIGMSCFFNREGKMEIRDLTESNITINADSYFLHGL
                     TKSEIEYQIAGITCKTDKKSLTVGMTTGRSLELDNVFITQSALNDLYYKLKNLTYYPY
                     NLNYQGHLLLEVGQWVTIQTNKKETFKVPVLSQSFIFKGGLRGRISADSKAGNDTQYS
                     YEGTITKQIKQQDGFEAKIQAQIEAADKDFDQKVDKIKKDFNDQVELAKARAEEVKRE
                     LSDTINQRFNSFDNGPLKEAKRKAEEALRNAGASSSLAQESKRIGLDSVARLEAFKSQ
                     TTSAQTALSGDLDALKRTIANDIRPKQAQAEAEIAKQVEALSRTKNELDGVKSAQATY
                     EETTTRRLSELTNLANGKASKSELTQTAEELSSKIASVQVGGINLLRNTASLLIGDRS
                     KGCWMSSSGGNGRAISVEVLAPPKKMIKNMIRVIENTNGGNKDLTQLVRLRIGEKYTI
                     SCYARVASDSPNANVNLLFRSWANNTDLNRKFQKSISHKNWQKYSFTFTADAIENSIQ
                     FGQSGAGIIEICAPKIESGTLATDYSEAPEDIEGQISTVESTFKQRANSLDAGVSRLT
                     EGLRTKVDISALNVTAENIRQSVKSLETDTQNKLNQKLSQAEFEVRAGSIRQEILNAT
                     KDKADKTLVVSEAGKLREEFSKMKVGGRNLWIKSKTVGAVIEKLPENHVTGQKECYRL
                     ENNSTLTFNLEPDFSSRLYQKVTFSAWIKYENVVQGRNFWNVFNCFKHYLFRKNSETG
                     VQSGPDYATLGMYKGSADWKYITFTYDYSEKTNFDQLKTSLRFNLEGATSGTAWVTGI
                     KVEIGSVATDWSPAPEDADGLITEAKATFERTAQGLRTDLSAIQEYVNKDGQRQEALQ
                     RYTREESTRQATAVRELVNRDFVGKATYQEDVKGINQRIEAVKTSANKDIASQIASYR
                     QSVDGKFTDISSQITTYKQDVGGQISGLSNRLTSSEQGTTTQISNLSNRINSNKQGTD
                     NQISNLKTQVATNKDNAERQMGRISDQVSANKANADSQFANVTNQLVRKVETTDFQRV
                     KETSKLYERILGNTENGIADKVARMALTNQLFQVEVGKYSVSGPNLIKNSDFKNATNE
                     WGSTQNLGRLVKHSFYHNGQKDLMRLSNATKNENFLYSHRFNLERNTDYVLNFRGFNN
                     SALASYDVYILGRRAGESDGFTIVKKVVSSKKLSTSRCEDVSVTFNSGEMDNAYIRFD
                     NNGSSSGTADLYITEVDLYKGYKPRTWQPHPEDAVADANKKLEATQTKMTQLAGSWVV
                     ENINSAGDIISGINLGANGHNRFVGKLTHITGETLIDRAVIKSAMVDKLKTGNFEAGS
                     VTTTILDAEAVTAEKLKVDDALIRKMTANDAFIDRLTSKRIFSTKVESVISSSTFLEA
                     YQGRIGGFTLGQFDQGGGRWISGVNQFSVGMGNGAGHGVRTAFWANWGNNWNYAGPKA
                     WNVNTDGKMYCRNEVGFYDQVDFSNSSRANFYGNTTFSRSPVFSNGIELGSKDVLGDG
                     WNPKGGRNAVVWWNQVGSGSVKYWMEQKSDRRLKENITDTAVKALDKINRLRMVAFDF
                     IENKKHEEIGLIAQEAETIVPRIVSRDPENPDGYLHIDYTALVPYLIKAIQELNQKIE
                     KMEKTIA"
     gene            52853..53056
                     /locus_tag="VYO11_000481"
     CDS             52853..53056
                     /locus_tag="VYO11_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001091107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1595085.1"
                     /translation="MNTEQLNQALQMTISEMSTTSTNSMIASNILSIQLNEQREENQR
                     LQARVDELEALLDEQTKPADKGE"
     gene            53059..53409
                     /locus_tag="VYO11_000482"
     CDS             53059..53409
                     /locus_tag="VYO11_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1595086.1"
                     /translation="MAETIQNTDNLLDLTKITEPFDLASALRYMKENGEFIRCKNVSD
                     DFYMYRDVQKRPVIVNGRRQLKDVETVWAFNQWGGTIATINVAVLLNHEFYIMKFDAE
                     GNPDWTDPTVKPKE"
     gene            53419..53835
                     /locus_tag="VYO11_000483"
     CDS             53419..53835
                     /locus_tag="VYO11_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003038967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HEV1595087.1"
                     /translation="MQIEFFNFLRSVVQTEDGLVLYALTLIVSMEIIDFVTGTIAAII
                     NPDIEYKSKIGINGLLRKISGVLLLMILIPASVLLPEKTGFVFLHSICLGYIAFTFQS
                     LIENYRKLKGNVTLFQPIVKVFQRLLEKDDDTKKGE"
     gene            53839..54171
                     /locus_tag="VYO11_000484"
     CDS             53839..54171
                     /locus_tag="VYO11_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001186229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HEV1595088.1"
                     /translation="MQQITEIITNGAISILVVLAGVVVRAVKDYLVQKGGEKTIKIVE
                     ILAKNAVNAVEQVAAETGYKGDEKLAQARAKVRAELTKYNISMTDKDLDTFVESAVKQ
                     MNDAWKGR"
     gene            54175..>54680
                     /locus_tag="VYO11_000485"
     CDS             54175..>54680
                     /locus_tag="VYO11_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HEV1595089.1"
                     /translation="MDIDRNRLRTGLPQVGVQPYRQVHAHSTGNRNSTVQNEADYHWR
                     KDPELGFFSHVVGNGRIMQVGPVNNGSWDVGGGWNAETYAAVELIESHSTKEEFMADY
                     RLYIELLRNLADEAGLPKTLDTDDLAGIKTHEYCTNNQPNNHSDHVDPYPYLAKWGIS
                     REQFKQDI"
BASE COUNT        17578 a         9549 c        12420 g        15133 t
ORIGIN      
        1 agacgttttt atgttataat gatagcgatt aaattcgagg tgaaaaatgg cacatttatt
       61 agaaaaaact agaaaaatta catcaatttt gaaacgctca gaggagcagt tgcaggatga
      121 gctcccttac aacgctatta cgcgtcagtt agcggatatt attcattgca atgcctgcat
      181 tatcaatagt aagggacgtc tgcttggcta ttttatgcgt tataaaacaa atacagatcg
      241 cgtagagcaa ttcttccaaa ctaagatttt cccagatgac tacgttcaag gggctaatat
      301 gatttacgaa acagaagcaa acttgcctgt tgagcatgat atgagtattt tccctgttga
      361 gagtagagat gattttccag atggcttgac gactattgca ccgattcatg tatcggggat
      421 tcgccttggt tctttgatta tttggcgtaa tgataaaaaa ttcgaagatg aggacttggt
      481 tcttgttgag attgccagta ccgttgttgg gattcagctt cttaacttcc aacgtgaaga
      541 agatgagaaa aatattcgtc gtcgtactgc tgtcaccatg gcggtcaata ccctttctta
      601 ctccgaactc cgtgctgttt cagcaatttt aggggaatta aatggaaatg aagggcagtt
      661 gactgcgtca gtgattgcag atcgtatcgg aatcactcgc tctgtgattg tcaatgctct
      721 tcgtaaactt gagtctgcgg ggattattga aagtcgctca cttggaatga agggaaccta
      781 tcttaaggtc ttgatttcag atatttttga agaagtgaag aaaagagatt actaatgaca
      841 aaggctttaa tttcgattga ttatacagaa gattttgttg ctgatagtgg gaagctgaca
      901 gcaggtgctc cagctcaggc gatttcggat gccattagca aggtaactcg attggctttt
      961 gaacgaggag attatatctt ctttactatt gatgctcatg aagaaaacga ttgtttccat
     1021 ccggaaagta agttatttcc tcctcataat ctgattggga cgagtggacg gaatttatat
     1081 ggagatttgg ggatctttta tcaagagcat ggttcagaca gtcgtgtctt ttggatggat
     1141 aaacgccatt actcagcttt ttcagggact gacctagata ttcgtttgag agagcgtaga
     1201 gtgtctaccg ttatcttaac aggtgtcttg acggatatct gtgtcctaca tacagctata
     1261 gatgcctata atctaggata tgacatcgag attgttaaac cagctgttgc ttccatctgg
     1321 cctgaaaatc atcaatttgc cctaggtcat ttcaaaaata cactcggagc taagttagta
     1381 gatgaaaatc taaatgaact ttctgagtaa cctggttggt gaaaatgaaa aaatttgaaa
     1441 aaaagtgttg acaagcatcc caaaagttga tatactagta aagtaatcga cgcggggatg
     1501 gcggaattgg cagacgcgca ggactaagga tcctgtgacc gctttaggtc gtgagggttc
     1561 aagtccctct ctccgcatag gaaaagagtt agctaaagct agctcttttg tatttctcta
     1621 aaaaattaga atccagtcaa atgtagtgga gaatcagcga aaatatggga aaactgatcc
     1681 ttgtttctgc ttttgtcata gaagaataat aaagattatc ttcttcaaat tctccgatat
     1741 tctctaaagt tttgtgcaag ttgcacagaa cttttttatt tttttggtca tcttgccata
     1801 gaaatataaa gcgttttcat ctataatata attatcaaaa gacaaaagga gttcacctca
     1861 tggtagaatt gaatcttaaa aatatttaca aaaaatatcc aaacagcgaa cactattcag
     1921 ttgaagattt caacttgaac atcaaagata aagaatttat cgttttcgta ggaccttcag
     1981 gatgtggtaa atcaactaca ctccgtatga ttgctggtct tgaagacatt acagaaggta
     2041 ctgcatctat cgatggcgtg gttgtcaacg acgtagctcc aaaagaccgt gatatcgcca
     2101 tggtattcca aaactacgct ctttacccac acatgactgt ttatgacaac atggctttcg
     2161 gtttgaaatt gcgtaaatac agcaaagaag acattaacaa acgtgttcaa gaagcagctg
     2221 aaatacttgg attgaaagaa ttcttggaac gtaaaccagc tgacctttca ggtggtcaac
     2281 gtcaacgtgt tgccatgggg cgtgcgattg tccgtgatgc gaaagtattc ttgatggacg
     2341 aacctttgtc aaacttggat gccaaacttc gtgtatcaat gcgtgctgaa atcgctaaaa
     2401 ttcaccgtcg tatcggagct acaactatct atgtaactca cgaccaaaca gaagcgatga
     2461 cacttgcaga ccgtatcgtt attatgtcag ctactaagaa ccctgctggt acaggtacta
     2521 tcggacgtgt agaacaaatc ggtactcctc aagaagttta caaaaatcca gttaacaaat
     2581 tcgttgcagg attcatcgga agcccagcta tgaacttcat caacgtgaaa ttggttggta
     2641 gcgaaattgt ttctgacggt ttccgtttga aagtgccaga aggagcattg aaagttcttc
     2701 gtgaaaaagg ctacgaagga aaagaattga tctttggtat ccgtccagaa gacgtgaatg
     2761 cagaacctgc tttccttgaa acattcccag actgtgttgt aaaagcgact atctctgtat
     2821 cagaactgct tggttcagaa tctcaccttt actgccaagt tggtaaagac gagtttgttg
     2881 caaaagttga tgctcgtgac tacttgcaaa caggtgcaac agttgagctt ggatttgact
     2941 tgaacaaagc acacttcttc gatgtagaaa ctgaaaaaac aatctactaa aataaataaa
     3001 attcaaagca ctacaagaaa agatatctct ttatcaattg tagtggagag atatcagttg
     3061 atctagggag agaaacaaaa tgcttctctc ctttttgcta gggaagtcat attatgcatc
     3121 tatattgtga tgctctttaa tactcttcga aaatctcttc aaaccacgtc aacgtcgcct
     3181 tgccgtacgt atgattactg acttcgtcag ttttatctgc aacctcaaag ctgtactttg
     3241 agcagcttac ggctagtttc ctagtttgct ctttgatttc cattgagtat tatttgtggg
     3301 taccatctac aagtgaagct atatgcgtaa actacgtgag caattgaatt cgaactagag
     3361 aggtaataat aaatttatgc tatagttatg gtgacttgta tgcttttgat tctagtttat
     3421 caaataatag attagaattg tcagataata tcattttgtg ttataatgaa gaaaaaacag
     3481 aggtgttcaa atgtcagaag caggtcataa gtttttagca aaattgggga aaaaacgctt
     3541 acgtccaggt ggaaagcgtg ccacagattg gttaattgca gaaggaggat tttcaaaaga
     3601 aaagagaata ctagaggttg cgtgtaatag gggaactaca gcaattgagt tggcacagcg
     3661 ttttggttgc aagataactg ctgttgatat ggatgctcaa gctttagaag tggctaaaaa
     3721 atctgctgga acggcaggtg ttgctcattt aatcagtttt gaaagagcaa atgcaatgaa
     3781 acttccttat caagatgcta gttttgatat tgttataaat gaagctatgc tgactatgca
     3841 agccgatcaa gctaagaaaa aatgtgtaat ggaatatcta agggtattaa aacctggagg
     3901 tcttctcttg acacatgatg tgcttcttaa ggaagctaaa gagtctatca gacaggaatt
     3961 atcacaagca attcatgtaa atgtaggtcc tttaactcaa gatggttggg aacaggtgat
     4021 gatagaatca ggttattgtg atgtgaaagc attgactggt gaaatgacat taatgaaatt
     4081 atcgggtatg atttatgacg aaggtttgct aggaactttg aaaatttgtg taaatgcttg
     4141 taaaaaggag aatagaaagc agtttttaac tatgtataaa atgtttgcta agaataaaca
     4201 gaaattgggc tttattgcga tggctagtta taaatcgtca aaacgttaga taattattga
     4261 agttaacttt tccttttttc tttcttaaaa aatatgctat aatagagagt aaaaaacttt
     4321 gaaagaaaga aaaaagatga atttaaaaga ttacattgca acaattgaaa attatccaaa
     4381 ggaaggcatt accttccgtg atattagtcc tttgatggct gatggaaatg cttatagcta
     4441 cgctgttcgt gaaatcgttc agtatgctac tgacaagaaa gtcgacatga tcgtgggacc
     4501 tgaagctcgt ggatttatcg tgggttgtcc agttgccttt gagttgggaa ttggttttgc
     4561 gcctgttcgt aagccaggta aattgccacg cgaagttatt tctgctgact atgaaaaaga
     4621 gtacggtgtc gataccttga ctatgcacgc ggatgccatt aagccaggtc aacgtgttct
     4681 tattgtagat gaccttttgg cgacaggtgg aactgttaag gcaactatcg agatgattga
     4741 aaaacttggt ggtgttatgg caggttgtgc cttccttgtt gaattggatg aattgaacgg
     4801 ccgtgaaaaa attggtgact acgactacaa agttcttatg cattattaat gaaaacagtc
     4861 cctagggctg ttttctctac actaggatat aaaaatagac tataactagt tagagaaaaa
     4921 ctataattga aaactatatc ttcttgcagt ataataaaag gactaagtgt ttgagatttg
     4981 tcttcaaaca tatgcaatta ttcctgaaag agtacagtta ggagagggtt atgccgattc
     5041 gaattgataa aaaattgcca gctgttgaga ttttacggac agagaatatc tttgtcatgg
     5101 atgatcaacg tgctgcccac caagatatcc gtcctttgaa gattttaatt ttaaatctca
     5161 tgccacagaa aatggtcaca gagacccagt tgttgcgcca cttggctaat acacccctac
     5221 aactggatat tgattttctc tatatggaga gccaccgttc taaaacaact cgttcagagc
     5281 acatggagac cttctataaa acttttcctg aagtcaagga tgagtatttt gatgggatga
     5341 tcatcacggg tgctccagtt gagcatttac catttgagga agtggactat tgggaggaat
     5401 ttagacagat gcttgagtgg tctaagactc atgtctattc gacccttcat atctgttggg
     5461 gggctcaggc tgggctttat ctgcgctatg gtgtagaaaa ataccagatg gacagtaagc
     5521 tatcaggtat ttatcctcag gacaccctaa aagagggtca ccttctattt agaggctttg
     5581 atgatagcta tgtatcccct cattcacggc acacggagat ttctaaggaa gaggtcttaa
     5641 acaagaccaa tctcgagatt ttatcagaag gacctcaggt tggggtttct attttggcca
     5701 gtcgtgattt acgagaaatt tatagttttg gtcatttgga gtatgaccgt gataccttgg
     5761 caaaagagta ttttcgagat cgtgatgcag gtttcgaccc acatattcca gaaaattact
     5821 ttaaagatga tgatgttaat caggtacctt gtctttgttg gtcttcatct gcagccctct
     5881 ttttcagtaa ttgggtaaac catgcggtct atcaggagac gccttttgac tggagaaaga
     5941 tagaagatga tgcatctgca tatgggtatt tataagagga attatgacat atttagacgc
     6001 ttttaaatca ggtgccttgg ttttaccgag tgccctgctc ttgcatttta aggaactctt
     6061 tccttctagc gacgattttc tggtttggca atttttctat ttgcaaaata cgacaggctt
     6121 agaagaaatg tcgccaagcc agattgctga aaggattggc aaggaaattt cggatgtcaa
     6181 ccagtccatt tctaatctga cggaaagggg actgctccag tatcgtacta tcgaattaaa
     6241 tggcgaaatt gaattgctct ttgatgctag tttggccttg gaacgtttgg atgacctgtt
     6301 tggagcagtt cattcaagtt cagaccagct aacacctcaa aaccagctca aggatttggt
     6361 ggaaaccttc cagcaggagt tgggacgatt gttgacgcct tttgagattg aggatttgac
     6421 caagacacta aaggaagatg gaaccagtgc tgacttgatt aaggaggctc ttcgtgaagc
     6481 tgttttgaat ggaaaaccaa actggaagta cattcaggcg attttgagaa actggcgcca
     6541 tgaaggaatc aagagtgtgg ctcaaattga ggccaagaga gcagaaagag aagcaagcaa
     6601 tcctcagttg acacaggtat ctgcagattt cataaatgcc atggatctct ggaaggatta
     6661 atccatgcaa gtaggcttga aatccgagta agatttgcaa gctgtgtata attgtgatag
     6721 aataaataga aaataaattg aaaaaagagg tatgtgaaat gtcacgtaaa ccatttatcg
     6781 ctggtaactg gaaaatgaac aaaaatccag aagaagctaa agcattcgtt gaagcagttg
     6841 catcaaaact tccttcatca gatcttgttg aagcaggtat cgctgctcca gctcttgatt
     6901 tgacaactgt tcttgctgtt gcaaaaggct caaaccttaa agttgctgct caaaactgct
     6961 actttgaaaa tgcaggtgct ttcactggtg aaactagccc acaagttttg aaagaaatcg
     7021 gtactgacta cgttgttatc ggtcactcag aacgccgtga ctacttccat gaaactgatg
     7081 aagatatcaa caaaaaagca aaagcaatct ttgcgaacgg tatgcttcca atcatctgtt
     7141 gtggtgaatc acttgaaact tacgaagctg gtaaagctgc tgaattcgta ggtgctcaag
     7201 tatctgctgc attggctgga ttgactgctg aacaagttgc tgcctcagtt atcgcttatg
     7261 agccaatctg ggctatcggt actggtaaat cagcttcaca agacgatgca caaaaaatgt
     7321 gtaaagttgt tcgtgacgtt gtagctgctg actttggtca agaagtcgca gacaaagttc
     7381 gtgttcaata cggtggttct gttaaacctg aaaatgttgc ttcatacatg gcttgcccag
     7441 acgttgacgg tgcccttgta ggtggtgcgt cacttgaagc tgaaagcttc ttggctttgc
     7501 ttgactttgt aaaataatca gtaagtagca aaagctaggt ggaacagcat tcagatgtct
     7561 gttacatttt ttataggaga gaaagattga aaacaaaaat tggattagca agtatctgtt
     7621 tactaggctt ggcaactagt catgtcgctg caaatgaaac tgaagtagca aaaacttcgc
     7681 aggatacaac gacagcttca agtagttcag agcaaaatca gtcttctaat aaaacgcaaa
     7741 cgagcgcaga agtacagact aatgctgctg cccactggga tggggattat tatgtaaagg
     7801 atgatggttc taaagctcaa agtgaatgga tttttgacaa ctactataag gcttggtttt
     7861 atattaattc agatggtcgt tactcgcaga atgaatggca tggaaattac tacctgaaat
     7921 caggtggata tatggcccaa aacgagtgga tctatgacag taattacaag agttggtttt
     7981 atctcaagtc agatggggct tatgctcatc aagaatggca attgattgga aataagtggt
     8041 actacttcaa gaagtggggt tacatggcta aaagccaatg gcaaggaagt tatttcttga
     8101 atggtcaagg agctatgatg caaaatgaat ggctctatga tccagcctat tctgcttatt
     8161 tttatctaaa atccgatgga acttatgcta accaagagtg gcaaaaagtg ggcggcaaat
     8221 ggtactattt caagaagtgg ggctatatgg ctcggaatga gtggcaaggc aactactatt
     8281 tgactggaag tggtgccatg gcgactgacg aagtgattat ggatggtgct cgctatatct
     8341 ttgcggcctc tggtgagctc aaagaaaaga aagatttgaa tgtcggctgg gttcacagag
     8401 atggtaaacg ctatttcttt aataatagag aagaacaagt gggaaccgaa catgctaaga
     8461 aaatcattga tattagtgag cacaatggtc gtatcaatga ttggaaaaag gttattgatg
     8521 agaacgaggt ggatggtgtc attgttcgtc taggttatag cggtaaagaa gacaaggaat
     8581 tggcgcataa cattaaggag ttaaaccgtc tgggaattcc ttatggtgtc tatctctata
     8641 cctatgctga aaatgagacc gatgctgaga atgacgctaa acagaccatt gaacttataa
     8701 agaaatacaa tatgaacctg tcttacccta tctattatga tgttgagaac tgggaatatg
     8761 taaataagag caagagagct ccaagtgata cagacacttg ggttaaaatc atcaacaagt
     8821 acatggacac gatgaagcag gcgggttatc aaaatgtgta tgtctatagc tatcgtagtt
     8881 tattacagac gcgtttaaaa cacccagata ttttaaaaca tgtaaactgg gtagcggcct
     8941 atacgaatgc tttagaatgg gaaaaccctt attattcagg agaaaaaggt tggcaatata
     9001 cctcttctga atacatgaaa ggaatccaag ggcgcgtaga tgtcagcgtt tggtattaag
     9061 caatgatttg aaagagggat gtgatagtag caccctcttt ttctttgttt tatgatagtt
     9121 catcctcgag taaattcaag atcttgctcg gaaatgaagc ttatatagta gattgaatat
     9181 agacaaatac cttgtgattg gtaaaacatt ttagaaattc atttaccttt cctaatcgac
     9241 ttggtttcat cttatttcaa tctattatag tattggggaa tttcttcaaa ccacatcagc
     9301 ttggtcagtt ctacctgcga cctcaaaact tgtgctttgg tcaagctggg tttagtttcc
     9361 tagtttgctg atggatttcc attgactata agcatccaac cctctttttg tcttctaaag
     9421 aattcttaaa ttatcagtct attgcaactt ttctcatata agttctttgt cttgctattg
     9481 gttttcctta gtagtatact aaggtagtaa tcagtaagaa gtgattacaa ataataatga
     9541 atgaggtaaa ataaaatggt agaattgaaa aaagaagcag taaaagacgt aacatcattg
     9601 acaaaagcag cgccagtagc attggcaaaa acaaaggaag tattgaacca agctgttgct
     9661 gatttgtacg tagcccacgt tgctttgcac caagtacact ggtacatgcg tggtcgtggt
     9721 tttcttgtat ggcatccaaa aatggatgag tacatggaag ctcttgatgg tcaattggat
     9781 gaaatcagcg aacgcttgat cacacttgga ggtagcccat tctctacatt gacagaattc
     9841 cttcaaaaca gtgaaatcga agaagaagct ggtgaatacc gcaatgttga agaaagcttg
     9901 gaacgtgtcc ttgctatcta ccgttacttg tcagaacttt tccaaaaagg tttggatgtc
     9961 actgatgaag aaggtgacga tgtaacaaac ggtatcttta cagatgctaa gactgaaacg
    10021 gataaaacaa tctggatgct tgcagcagaa cttggacaag cacctggttt gtaagaaata
    10081 atagcaacat atataaatct gtaagaaatt tcttacagat tttttctatc ttgtaagcta
    10141 tcccaaacca gtcttttttt gagttttttg ataaaatagt actatcagtg aaaaggatgg
    10201 aagcatgact aaaaaaattg tagctatttg ggcccaggat gaagagggtg tgattggtaa
    10261 ggacaatcgt ctgccttggc atttgccagc agaattgcaa cacttcaaag aaacaactct
    10321 gaatcatgct atcttgatgg ggcgtgtgac ctttgatgga atgggacgtc gactgcttcc
    10381 aaaacgggag accttgattt tgacacgtaa cccggaagaa aagatagatg gggttgctac
    10441 ttttcacgat atccagtctg tcctagactg gtatcagggt caagacaaga atctttatat
    10501 tctcggtggg aagcagattt ttcaggcttt tgaaccctat ttggatgaag tcattgtcac
    10561 tcaaatccat gctcgggttg agggagatac ctatttccct gaagagtttg acttgtctct
    10621 ttttgagaca gtttcaagca aattttacgc caaagatgag aagaatcctt atgattttac
    10681 catccaatac cgcaagagaa aggaagtcta atggaacgga gtttatttgg tctattcacg
    10741 gcttttctgt gtttcatctg ctttctggca ggagcacaag cttttcgtaa aaagcgttac
    10801 gggctttcta tcctcctttg gttaaatgcc tttaccaatc tggtcaatag tattcatgct
    10861 ttttacatga ccttatttta gatagaatga cagtatagaa tggaaggaaa tcatgtctac
    10921 aaatagaaaa aatgatatga tggtttattg ctcattttgt ggcaaaaacc aagaagaagt
    10981 acaaaaaata attgctggca acaatgcttt tatttgtaat gaatgcgtgg agttagctca
    11041 ggaaatcatt cgagaagaat tggttgagga agtcttggca gacttgtctg aggtgccaaa
    11101 accaattgaa ctcctccata tcttgaacca ctatgtaatt ggtcaagatc gtgccaagcg
    11161 tgccttggca gtggcggttt ataaccacta caaacgcatc aatttccacg atacacgcga
    11221 agagtcagaa gatgtggatt tgcagaagtc aaacattttg atgattggcc caactggttc
    11281 agggaaaact ttccttgccc agaccttggc taagagcttg aatgtacctt ttgctattgc
    11341 ggatgcgaca gctctgacgg aggctggtta tgtgggtgag gatgtggaaa atatcctcct
    11401 caaactcttg caggttgctg actttaacat cgaacgtgca gagcgtggca ttatctatgt
    11461 ggatgaaatt gacaagattg ccaagaagag tgagaatgtg tctatcacac gtgatgtttc
    11521 tggtgaaggg gtgcaacaag cccttctcaa gattatcgag ggaactgttg ctagcgtgcc
    11581 gcctcaaggt ggacgcaaac atccacaaca agagatgatt caagtggata caaaaaatat
    11641 cctcttcatc gtgggtggtg cttttgatgg tattgaagaa attgtcaaac aacgtctggg
    11701 tgaaaaagtt atcggatttg gtcaaaacaa taaggcgatt gacgaaaaca gctcatacat
    11761 gcaagaaatc atcgctgaag acattcaaaa atttggtatt atccctgagt tgattggacg
    11821 cttgcctgtt tttgcggctc ttgagcaatt gaccgttgat gacttggttc gcatcttgaa
    11881 agagccaaga aatgccttgg tgaaacagta ccaaaccttg ctttcttatg atgatgttga
    11941 gttggaattt gacgacgaag cccttcaaga gattgctaat aaagcaatcg aacggaagac
    12001 aggggcgcgt ggacttcgct ccattatcga agaaaccatg ctagatgtta tgtttgaggt
    12061 gccgagtcag gaaaatgtga aattggttcg catcactaaa gaaactgtcg atggaacgga
    12121 taaaccgatc ctagaaacag cctagaggtg actatggaac ttaatacaca caatgctgaa
    12181 atcttgctca gtgcagctaa taagtcccac tatccgcagg atgaactgcc agagattgcc
    12241 ctagcagggc gttcaaatgt tggtaaatcc agctttatca acactatgtt gaaccgtaag
    12301 aatctcgccc gtacatcagg aaaacctggt aaaacccagc tcctgaactt ttttaacatt
    12361 gatgacaaga tgcgctttgt ggatgtgcct ggttatggct atgcccgtgt ttctaaaaag
    12421 gaacgtgaaa agtgggggtg catgattgag gagtacttaa cgactcggga aaatctccgt
    12481 gcggttgtca gtctagttga ccttcgtcat gacccgtcag cagatgatgt gcagatgtac
    12541 gaatttctca agtattatga gattccagtc atcattgtgg cgaccaaggc ggacaagatt
    12601 cctcgtggta aatggaacaa gcatgaatca gcaatcaaaa agaaattaaa ctttgaccca
    12661 agtgacgatt tcatcctctt ttcatctgtc agcaaggcag ggatggatga ggtttgggat
    12721 gcaatcttag aaaaattgtg aggaaaagaa aatggcaaaa acaattcata cagataaggc
    12781 cccaaaggct atcggaccct atgttcaagg aaaaatcgtt ggcaaccttt tgtttgctag
    12841 cggtcaagtt cccctatccc ctgaaactgg ggaaattgta ggagagaata tccaagaaca
    12901 gacagagcaa gtcttgaaaa acatcggtgc tattttggca gaagcaggaa cagactttga
    12961 ccatgttgtc aaaacaactt gtttcttgag cgatatgaac gactttgttc cttttaatga
    13021 ggtttaccaa acggccttca aagaggaatt cccagctcgt tcagctgtgg aggtagctcg
    13081 tcttcctcgt gatgtaaaag tcgaaattga agtcatcgca gagattggat aagctagttg
    13141 aagtttggtg ttgccaaact tcttttgata taaggagaaa aagatgacaa agaaacaact
    13201 tcacttggtg attgtgacag ggatgagtgg cgcagggaaa actgtagcca ttcagtcctt
    13261 cgaggatcta ggttatttca ccattgataa tatgccgcca gctctcttgc ctaagttttt
    13321 gcagctggtt gaaattaagg aagacaatcc taagttggcc ttggtagtgg atatgcgtag
    13381 ccgttctttc ttttcagaga ttcaagctgt tttggatgag ttggaaaatc aagatggttt
    13441 ggatttcaaa atcctctttt tggatgcggc tgataaggaa ttggtcgctc gttacaagga
    13501 aaccagacgg agtcacccac tagcagcaga cggtcgtatt ttagatggaa tcaagttgga
    13561 acgtgaactc ttggcacctt tgaaaaatat gagccaaaat gtggtggata cgactgaact
    13621 cactccacgt gagctgcgca aaacccttgc agagcagttt tcagaccaag aacaagctca
    13681 gtctttccgt atcgaagtca tgtctttcgg atttaagtat ggaatcccga ttgatgcgga
    13741 cttggtcttt gatgtccgtt tcttgccaaa tccctattat ttaccagaac tgagaaacca
    13801 aacgggtgtg gatgaacctg tttatgatta tgtcatgaac catcctgagt cagaagactt
    13861 ttatcaacat ttattggcct tgattgagcc gattctgcca agttaccaaa aggaaggtaa
    13921 gtccgttttg accattgcca tgggatgtac gggtggacaa caccgtagtg tggcatttgc
    13981 taaatgcttg gcgcaggact tatccaagaa ttggtctgtt aatgaagggc atcgcgacaa
    14041 agaccgcaga aaggaaacgg taaaccgttc atgagaaaac caaagataac ggtgattggt
    14101 ggagggactg gaattcccgt cattctaaaa agtctgcggg aaaaagatgt ggaaatcgca
    14161 gctatcgtga cggtggcaga tgatggtggt tcttcaggtg aactccgaaa aaatatgcaa
    14221 cagttgacac cgccaggtga tcttcgtaat gtccttgtgg ccatgtcgga tatgcctaag
    14281 ttttatgaga aggtctttca gtatcggttc tctgaggatg ccggagcctt tgctggccat
    14341 ccattgggaa atctcatcat tgctggcttg tcagaaatgc agggttcaac ctataatgcc
    14401 atgcagttat tgagcaaatt tttccataca acagggaaaa tttatccttc cagtgaccat
    14461 cctttgaccc ttcatgcagt ctttcaggat gggacagaag tggttggaga gagtcatatt
    14521 gtagaccatc gaggcatagt tgacaatgtc tatgtgacta atgctctaaa cgatgatacg
    14581 cctctggcca gccgtcgagt agtgcagacc atccttgaaa gtgacatgat tgtcctaggg
    14641 ccaggttccc tctttacctc tattttgccc aatatcgtga ttaaggaaat tgggcgggct
    14701 cttttggaaa ccaaggcaga aattgcctat gtctgcaata tcatgaccca acgtggggag
    14761 acggaacact ttacagatag cgaccacgtg gaagtcttgc atcgtcacct tggtcgccct
    14821 tttatcgaca ctgtcttggt gaatattgaa aaagtgcctc aggaatacat gaattccaac
    14881 cgttttgatg aatacttagt gcaagtggaa cacgattttg taggtctttg taagcaagtt
    14941 tcgcgcgtga tttcatctaa cttccttcgt ctggaaaatg gcggtgcctt ccacgatgga
    15001 gatttgattg tggacgagtt gatgcgcatt atacaggtga aaaaatgagt ttcacagtag
    15061 cagtaaaaga agaaatcctg ggccaacacc atctgagctg gcatgaatta tctgccatta
    15121 tcaaaatgtc tggtagcatc ggtctctcga cttcgggctt gactttgtca gttgtgacag
    15181 aaaatgccaa actggcccgt cacctctatg agtcctttct tcatttctat gaaatcaaat
    15241 ctgaaattcg tcaccaccaa cgtagcaatc ttcgcaagaa tcgcgtctat accgttttta
    15301 cagatgaaaa ggtgcaggat ttgttaagtg atttgcactt ggcagactct ttctttggcc
    15361 tggaaacagg tattgatgag gcgattttat cggatgagga agcaggtcgt gcctatctct
    15421 gtggcgcttt cttggcaaat gggagcattc gtgaccctga gtcaggcaag taccagttgg
    15481 aaatcagttc tgtttatctg gaccacgcgc aaggaattgc ctcccttctc caacagtttt
    15541 tactggatgc caaggtgctt gagcgcaaga agggggctgt gacctatctc cagcgagcag
    15601 aagacattat ggacttcttg atagtaatcg gagccatgca ggcacgtgat gattttgagc
    15661 gggttaagat tttgcgagaa acccgtaacg acctcaatcg ggctaataat gccgagacag
    15721 ctaatatcgc tcggacagtt tctgccagca tgaagaccat taacaatatc agtaaaatca
    15781 aagatatcat gggcttagaa aatttgccag tagatttgca ggaagtggcg caactgagga
    15841 ttcagcaccc agactactct atccagcagt tagcagatag tctcagcacc cctctgacca
    15901 aaagtggtgt caatcacaga ctcagaaaaa tcaataagat agcggatgaa ttataacgat
    15961 ataaagcaac cccttgaatt atcaatatct tcaaggggtt ttgttgtgtt atgaaatcaa
    16021 aaaggggcaa ccaaggggca gaattaaaaa atagtatcta atttattgac cagtttatcc
    16081 tccatatctt cagtagtatg agaatagatt tccaaagtca tttttgcatt tgagtgccca
    16141 actcgatcca ttattgattt tattgggagg ccagactctg ctaaaaacga aatatgagaa
    16201 tgcctaaaaa tatggctaga taagtttttt tctattttgg cctgttttcc atattttttt
    16261 aatatctgta tgaagcaagc tattgttgta ggttgattcc atttttcaaa acagaaaata
    16321 taatcatcgc ttgacaatgg ctggaaacgt tcgctaagtc gtactatttg tctttgaata
    16381 gcttctatga cactctctga tactttgatt gtccgtattg aatttgtagt ctttggtagc
    16441 gtcttgattt tgtttactga atcaaaatta cctgtgatct caattttgtt gttttcgaag
    16501 tctatattct tcagttgtaa ggcagttaac tcaccatatc tcataccagt taatgtcagc
    16561 acaagaacca tatcagcgta cttttggtga tattctcgac gattaaggac atcgacaagt
    16621 gcttttattt cttgcatggt gagaaagttg ttacgctttt tttccagttc ttctaaagtc
    16681 tttggttttt gaggaatcgt agtataatcg acctcgttgt tttcaatgta agagtattga
    16741 acagcgtaat taaagatacc tctgagccta tgccgtactt ttttagctgt aatatatccg
    16801 ttgctttcaa taattttttc aatagcctct tgaagaaaac gcctgtcaag attagcaagt
    16861 atggtatcgg atggtatgac ttccttcatc ttcttatcaa ctgatttaca attatgtttt
    16921 gttgattcct ttactgtttg cgcccatgat ttataaaaaa ggttatagat ttcttcaaat
    16981 gtaatgcttt ctacttgttt tgtgcttagt tttttattta tcttctcttg caataagata
    17041 gcagcttgat ttcttgcctg gggagttttc ttctccatgg tcactgaaac tttttttaat
    17101 ttctcagtat atggatcttt atatcgctca aaaaatttgt attttccgtt cggaagttct
    17161 tccatccaca ttgattttaa cctcactttt tgataaaatg ggtatagtaa aaagggcttt
    17221 ttaatgcctt ttactatact ggatatcctc acactcaaag tttggcgatg gcgagtgtga
    17281 ggattttttg tttttatagt tattctgatg aactatccta tcaattcata atattcgtca
    17341 attaccatca attcgtctgt gactgttcta agctcatgtt tttgcatgaa ctggatatag
    17401 ttgaaagatt gatggtcgtc tgatagtgca agttcttctt ctagcaactt atgaatcatg
    17461 tgcctattag cctcattctc gcacctagtg tggttatttt tatatagtgc agtagaatgt
    17521 tccagatgtc ctaattcgtg gtatatgacc cgtttttttg cgttttcgga cagttcacgg
    17581 tttataaaga taatactaat ctctttgatg taaactccag gtctttgcca aagttcatta
    17641 tcaaagtaag cgagagtgac accgtgtgag tctactagct cttcaatagt cataggctat
    17701 catccttttt gtgttatttt gttgttaaaa tggttacgat gattgctagt atccccagta
    17761 aagtactaac taacagtccg ataaaccaat acatgaactc ttttttgctt ttagcttgct
    17821 cttctaatct cttattctct tgagttagaa acatagtctc tacacgtttc tcgaaattat
    17881 caaattttaa atcaacttgt tcaaatttta agtcgatttt ttcaaatccg ctacgcattt
    17941 cttgtctgag ttgatcaact tttaaatcaa ttttctcgaa tccatgctga gtgtcagaat
    18001 taattttatc aagttttaag tcgatttcag atttgctgta agtatcttgt gacataatat
    18061 tttcctccga taacatttct gactccatta tatcatgatt ttgtatgggt acagttttcg
    18121 atgaagattt agaagcgtaa agtgaagaaa ctttggaagg ggtaggtttg aaattatctt
    18181 gtgtgtccgg cattgtttac ccccactttc caaaatgatg ataactatat gctgtatcta
    18241 cttcctgacc gttttcgtcc atcaagacga agaaaaagta aaaatcgctc ggcttttcta
    18301 tcgtaaaatt aaagctaaaa tttccagtgg ccataccaaa gccgtcttca agtagcacaa
    18361 attcttgtct cgcaatattt attctcgtag catggacagg gtaagacgtg ccattaggga
    18421 agtgggcagt tagagacaag atataatctg tttcaggtct tagattaaag aagtctagaa
    18481 atgcaaccaa agatgtcgaa ccaggaaaca tatcgaaatt ggttattgtt cctagcaatt
    18541 gagctgtttc aggattgaca atactgattg ctgtcatctt ttctctgaac ggattcttct
    18601 tcattggaat gttcgtcata ctatctacct ctcaaataaa tctcaataat gttctgaatg
    18661 gcatcgatgt cttcttctgt aagtggcttg ccatcgaagg tcttggcatt ctctgccatc
    18721 tttcggaggt cgtcagacgt gtatcctgcg attgtatcat caccagcaat agcaggatta
    18781 tctgtgcggc caagtaagta gtcagttgag acattgaagt agtcggcgat ttcttgtaat
    18841 ctttcagcat ttggtttttt actcttcatg ctatagattg tatttctgct atatccaagt
    18901 gtttcttcga gagaatttat agaaattcct cgtttttggc aaagttcttt aattttttca
    18961 aacaaagaaa acattgattt atcagccttt ctaagacatg acaaaaaata tttaaacttt
    19021 tgtgtgtaaa gttgttgaca aaacacaatc aatagtttac aatagttttt gtaagtaagt
    19081 tacaactaaa aaaacaacta agaaataaat tataaaaatg ttttggcgaa cggtatttat
    19141 agttttatta gtgctttttc ttatgctttt attctaaaca atagattgta aaaagtcaag
    19201 cgacaacaca aaaaatagtt aaatttttag ttgtttctta tttacaaata agtaaatagg
    19261 aggaacgtac cgatggtaag tattcttaaa aatttagaac aagaaaaaga ccaccttgaa
    19321 aaaatcatta aggtagtcag cgctggtggt aaatttctga gattgccata tcaaaaaaag
    19381 tcacgctcga ttagtgagaa tctgaaattg atttctcaaa atcttgataa attgagcgag
    19441 caagttcaac aaaccacgaa tcagcattca tgatttcaag atgacgaaag aaacctgttt
    19501 tggtttccag ttcagaatcg tgtgcataac gtaatatttc tctagcaaag atggtttcaa
    19561 aatcaaaatc tttaccatca tcgtagatgt cgcgtttgct tgctttgagt aaatattctt
    19621 taaaagtcat aaggttaact cctttctgct tatattatag cagaaaaaga agaaagaaaa
    19681 agaaaggaga aaatatgcca gatatcgcaa acggtcgcga aagagttatt gctttcttga
    19741 aagagaaagg cattaaaaaa gcaactctag cggttgctta cggctttaaa cgacaggaag
    19801 tgacaaacat tctaagtgga acgactaaag gtccacgagc gaacagtttc attcttcagg
    19861 ttattgaaga ttatgggatt gagtaggaaa gatttgagga gtaggaaaat gagaccaaga
    19921 cgatatccgt atagtgggaa aaaagagtcc acctttgtga aggcagaccc tgaattggta
    19981 gaaaagattc taagaaacat cagttttctt gagcatttac aagttgtgtt agcaacgaaa
    20041 ctgtagtttc tgtgctgagt ttatgagcga caagaacgct atagaaaata gcttctctaa
    20101 tctctatgtc gattggatat ttttcaaata cttcatccaa catatctttg ataaccggaa
    20161 tagcatcgtt gataatgtct tgagaaactt gtaaaacatc ttctttagtt aatttagaca
    20221 tatagttttc ctcctttctg atggaatttt gactaaaacg gtgagaggtc ctagtcaaaa
    20281 ttattatagc aatttaggag gaaattacat cagtcttgag gctgatatag gaggttgaat
    20341 ggaagataaa atcatagaac ttgctgatta cttcatcagc gaatctacaa cgtacagaga
    20401 agcaaaaata gcgtgtgaga agctattgaa acaagtcagc catgagatag aactcagggc
    20461 gatggaaagt aggacagtct agaagacaac aaaaagcacc tgacggcaat caggcgcatg
    20521 acaaaattat tcaagaaaat tataacacga aaggagcaaa aatggaagca gttgaaattg
    20581 taagaattaa agatgtgatt attgaaaaag tctctgctaa tgatgaagag ttaaaacgta
    20641 tctttggatg ttcaaaacga caagcaggag agcgaagaag agaaatgcaa aaactcccta
    20701 gtcagcaaaa acatcttttg gatagtggac aacttgtaac gattaaaggt ttctatgaat
    20761 acttgcaata tcgtggaact aaagcttgga aaaaagaaat ggaaacaagc aagaaaatga
    20821 ggtcagcagg atgaacctac tatcaagaat caaaaactat ttttcggaag aggtcaaaga
    20881 aactaatctc gactggaaag aggtcgcttt agacctcaat caatcactaa ttgaaacaca
    20941 ggaaaaactt caagaagcga atcaagaaat cgcagacttg aagaaaatcg tagcaatcta
    21001 caaagaaaag gagaaagaaa aatgatggaa tacatttacc tggtaataat cgtaggaatt
    21061 ggactatggt cgctagtaaa taaactagat gaccacgctg aaatgaaaca aaaagagcgc
    21121 cagctgatag caaacaatgt cgcacggatg aatctgagaa attcagataa gcaatttact
    21181 tatgatgtag aaccgcctga agggttgaaa taaggaggag aaacatgact caagcggaac
    21241 aaattaggga atattataga gagcaccctg ctgcctcatg tgatgaagtg gctgaggttg
    21301 tcggtacaac aaaaagcaac gtaagtgcaa acctggccaa agacatcaag gcaggcagat
    21361 gcgttcgctt ggaagataag tcatacgact actcgcctta ctataaccat acacaggcac
    21421 tcactgagtt ggttgattgg aagaatgata ctagacgtga gtgggtggat atgctgacaa
    21481 gagcagcaga aaaagaaacg gttagcaatg ttatgcgttt gttaatcaaa gaagcaaata
    21541 aattgatgaa agaggtgacg aagtagatgg ttcgaaataa attgacagat ttaaccaata
    21601 ctcttttcgc ccagttggaa acattggacg atagggatct tactgcagat gaattaaaga
    21661 cggaactcca acgttcaaaa cagatggtcg caatctcagg tcaaatctta caagcaggtc
    21721 aattggcgct agatgctgaa aaattcaaag acaaggtagg tgaagtcaat gccccgattg
    21781 ctttgctgga aggatgagta tacagagtac atgcatgaga tatgccctgg ccgattaact
    21841 cctgaagtaa ccaggttact aaatgagaaa tttggtacga cctataccaa gactcaaata
    21901 ggagaagtac gcagacgttt agggttacct gttggaaaag tctatcaagg taaattgttg
    21961 acaaaagaac aacatgatta ccttgtgtca atccaaaaaa ataagatttc tcgcgatgtc
    22021 gcaaatgaaa tgaacctaaa atttggatta tcactgactg agaaacagat taagagttat
    22081 cgaagaaata ataatctaca tagtggtttt acaggaagat tcgagaaagg tcagactcct
    22141 cacaataagg ggaagaagta ccccaatatg ccaaaaaaca gcgggcagtt caaaaaaggt
    22201 aatcgacctc cgaattatgt acctgtcggt actatcaact acacaacaga cggttatcca
    22261 aaagaaaaga ttggagaacc taatcaatgg gttttgaaac accgcaaggt ttgggaggaa
    22321 catcacgggc caataccaaa agggcattcg attgtcttct tggacggtga taaaacaaac
    22381 tatgatattt caaacctggc atgtttatct aaaaacgaaa ttgctagaat gaatcaaaat
    22441 catttattta cgtccaacgc tgatttaacc aaatcaggta ttgaactaac aaaactcaca
    22501 aacaaaatca gagaggtaga aaaaaatggc tagtttatac gaactgacag gtcagtttct
    22561 gacagtttat caaatggata ttgatgacga aacaaaaacg gacacacttg aggctatcga
    22621 ttggcaagaa caattcgaac agaaagcaga aggatatgcc catgttatca agaatctaga
    22681 agccgacgtg gccatgtaca aggctgagga agagagcttc aaagccaaga aacaggtggc
    22741 acagaaaaag ctggattatg taaaggataa cattatggca gctatgaatg tcacggggca
    22801 aaccgaagtt aagagtggtg ccctgattat aaaaattgct aagaatccag aatcagtcaa
    22861 ggtcaacgaa gacgaccttc cgaaaaaata ttttacaaaa aaagtgacgc ttgcgccgga
    22921 caaaaaaaca ctcaaagagt tgcttaaatc tggcaagaaa gtcaaaggtg cggaacttgt
    22981 ccggacagaa aagttggtga ttaagtaatg gaattgatga ataaaacacg agtaacagat
    23041 tcactagcag ttgtgattgg accagaatcg attgaagtac ttgttactga aggttttcta
    23101 tttgatgttg cgattcgttt tgtaaaagta gacgaaacaa atcttgatca aggaaatgaa
    23161 aagccagtat tcactccgga atacaagctg gtcacagttg ctaaatacaa ggaaaaacct
    23221 atctttgaat cggaggaaga tattcgaaaa tttgagaagc aagcaaaaga agttaaatcg
    23281 ctatttgcct ttgcaaaggt aaataaacaa aattggttta acactgccct ttatccagga
    23341 gtgctaactg agaaagttgg tgtttgatga aaattttagc tattgatcca agcagtaata
    23401 aaattgaaac cagcacaaca ggagttgtct tgttggataa tgcaagatta gttgatagct
    23461 gggttgtctc ttatggtatg agaggtttcg ctgattggtt tcacgaaatc ggaacaaatc
    23521 ttgaattcga tgtagttatt gttgaagaat ttaaggcgag ggataacgac aagtcgaaag
    23581 ataatagcgt ggcagaaacc atcgcctata tccaactttg ctatccaggt gccattcttc
    23641 aattcaatgc aggttacaag tcggatattc caaacgatct tttgaaaatc ttagaccttt
    23701 ggaaatttga aaaaagtcat catcaagata ttcgagcagc agcaagactt ggattatttt
    23761 gggcaatgag aaatgatatt gaagaagtgg ttcatgatat cggaaaggtg gtgagtgagt
    23821 atcacaataa cgctaagaaa gtggcaagct gaagcgatta aaagaagtga acatttatct
    23881 aatggaatct ttttagaggc tcttgggggc agaggcaaaa caatctgcgc cctagctatc
    23941 tcaaaacata aaaatgctaa gaaaatcatc atcacaaaca acagattggc aatcttgaat
    24001 ggttggattg atgcagtcaa gtttatgaat tttgataaag atgttgagat tatcattcaa
    24061 acggatagat atcttcaaaa tcaagtcaaa aaagggcata aattagattg tgatgtgctg
    24121 atagtagacg aatggcagaa catgtcgtct gacaaacaag tggccttata tcgcaaaata
    24181 aagcgaaaat acacgatagg tctttcagcg acaccaatcc ggaaaaaagg acaaaatttc
    24241 tatccgcttg aaaaaacggt atttggttgg gcaaccccaa ataataaatt tgactggcaa
    24301 aagactcatg ggaaaatggt ctatgatcca ttcagctact caaaagagaa gtgggaagat
    24361 ttcaggaatt atgaaagtta tatctcaaac ttgccgaact ttttccgctg ggaagacatt
    24421 gaaaagattg agaatgcagt tgagaataac ggttttgaga ttaagtttta ccaaaagaga
    24481 gtcgcctctg gcaatccaga aaaacttgca gaatttagaa aactaaatct tgtaacagtg
    24541 gacggcaaaa ctgcaatggc caagcaatcg tttggaagaa agacctttga acgctacctt
    24601 aatcaaacag gcgtagcagt cgattttcca aaattaaagc cagtaaatgc ggatacgcca
    24661 ttgatgttac aacttgacgg tttaatcgaa cgagcaccac acgatatgtt gattgtcagt
    24721 aaatctaagc agattgtcaa cgtcattagc gagcgccatc ctgaaattgg aatctggacg
    24781 ggcgatattc aagaaggact ttataagaaa ttcgtggttg ctactagtca agtgttaggt
    24841 gtcggagtag acggcttgca acacaaatac caaactattg tcgtattgga tccagtagaa
    24901 gaaggttctg gagaatatga tgattatcga caattgctct ggcgtataac aggaagtcgt
    24961 cagcagcatg atgtaaatgt aattgaattt tattataaag aaagttaaaa aaaagaggaa
    25021 aacaaaatga ataaaacaac tgaaatgatc gtatttcgta gccgtaaaac tggagaattt
    25081 cttaattctt acaaggacag aagttcttta gcatttgcag ctgacttttg cagcttggaa
    25141 tattgtttga agcttcctcg taaaaaatac gaagacaaca aaaagactta caaggctctt
    25201 gctgcagctt ttgactgtga aattgtcgca gttgaagcgg aatacaaatt gacctatccg
    25261 aatggatcag aagttgaacc tatcaagcgt gaccgttcat caattgagga catgattaag
    25321 gatattattg gaggggttct ctaatggcat ttacacttcc agcaaataaa ccacaagttc
    25381 ctaaagatac cccacgaaat tttttcatct acggtgaaac catgagcgga aagtcttatc
    25441 ttgcaaatga attcccaaat ccaatcgttt tgaacacaga cgggaatgca gaagctaaca
    25501 ctgttccaag cattcagctg atcaatgaaa aagatgacaa gggacgaatt accaattcag
    25561 taattaagca gcttggagat atcttgcttg ctctccagac acagaagcac tcttatgaaa
    25621 cagtcgttat tgatgtaatt gacgatgtta ttgaaatgat taagattgca gtttgtgatg
    25681 aattaacccc agttggtaaa cctcgcttga aatccttgtc ggaaattcca tacggcaaag
    25741 gatacgactt ctttaaccaa gctatcacag aattagtcat tgacctcaaa gcattgccaa
    25801 tgaatgttat ttacatcagc cgtcaggtat ctgaatatga tgacaatggc aatgccacca
    25861 aagacaagcc aagcttgaaa gataagtatg tcaatcttat caatggaaac tctgatttga
    25921 tgatccacac tgaaaaactc ggcaacaact acaaccgtga ggttgaccgc aagcgtaaga
    25981 cctattatgc ggaccaggtt gatgacaagg ccatcttgaa aatcttggca actatccgtg
    26041 gggctgttga gcctgcaaag ggcaagctag cccctaaaaa agaagcagct aagacaacta
    26101 aaccagctaa gaccgaaaaa acaaaagagg cacctaagaa agaagttgac tctgatgatg
    26161 aactatttta agaaataaag gagaatacac atgagcttac tagatatcgc aaaatcaatc
    26221 aaaaaagagg gctttgaccc acgcaaagac agcgccaacg gtcctgcacc aatcccagct
    26281 ggtacttatc cagtagtcct gaagaaagca accttcaacg tatcggacaa aggctgggaa
    26341 agtcttggtt atcaatttga aatccgtggc ggtgattaca gtggacgctc tgaatttgca
    26401 acatttggca cactgactga atggaacggt aagaaccttg actgggcagt tgaacgcact
    26461 atgaaattct ttatcaaagc cttggtcctt gctggagaca gtatgcaagg aaatgaagaa
    26521 gacggtaaag ccttggaaga ggctctaaaa cgtaaggcag ttggctctta ctacaacctt
    26581 gttatctctg tgactaaggg gaaagatggc cgtgagttcc gaaactatga ccttgaagaa
    26641 gaagaagcac aaccgctgac tgaagctgat attgatgacg atgacctccc tttttaagaa
    26701 ataacaagtt ctgggtcatt gatgaaactg atgaggaatt tggtcctttc acgacagtag
    26761 aagaggctta tacagctatg ctaacatact tggatatgac tgaagccgaa tatcagtcaa
    26821 actatacggc ccaggaactt gtttatattt acaaagagga gaaaaaacca tgccgtcgat
    26881 gaaagaatac gcattacagt accaaaagtt agggttctca gtcattccaa tcaatcctaa
    26941 aaacaagatg cctttgattg attttgctga taagccagcc atgactccat ctgagattga
    27001 aaacttttgg gacggctacc ctaatgcaaa cattgcccta aagactacca acttctttgt
    27061 cattgatatt gacaaacacg gcaaatcgaa cggttttgaa tcgctaaaaa aatggaaaca
    27121 tctaaattta atcgaaccga cactgcaagc taagacggct agtggcggta aacatctatt
    27181 ctacttcaaa cgagaagatg agccgatcac tcagatgatt ggattcttgc ctggtgttga
    27241 tattaaggct cacgaaaata attatgtgtt agtcgcaccc tctgccacag ataaagggca
    27301 gtatgagtgg gatctggaaa agtctaagga aggtggcacg atggtcactc cttcaaaaga
    27361 tttaatccag tctataaaaa aacagtatgg cgaaactcac ggttataagt atgatggtaa
    27421 ggacggtctt agggatttag ttagacgttc acaaaccaga gaccgaacac agactacaga
    27481 tctctttgaa accatcgccc ttggttttgg tgatgaaggt ggacgaaatg acaaactagc
    27541 aaaattcgta ggtggtctct tatatcgtgc ggtcgacgat ggtgtagttg ttcaacttgc
    27601 aagattagca aatgcaaata gtccaaaccc tttgcctgaa aaggaaatga tgcgtactat
    27661 tgaaagtatg attaaaaaag ataggaggtg attgtgattg gtaatgtagt aagtattgac
    27721 tcacaaccta agatgataac gactgccaag ggagacatca aggccaacag tccaagtaat
    27781 gtgttgatgt ctttcaaagc tgatgatcag ttgagtattt acctaaagca caacgatttt
    27841 tcccaagagc atgaactcct taaagatatc aagatcggca acactctttt taaaaaaggt
    27901 gagctccctt ctaactttga ttcagtcgta aaagtttact ttgaaagtgt gttaggtgtt
    27961 gctttctcaa accaagcgat gcttgatggc atggagactt tcttttcaga aagatcatac
    28021 aatccagtta ttgagtatat ggagagagca actgaaaagt gggacggcag aaaccggatt
    28081 gaccgcatgc ttcaagtata tctcggcgct gaagatatcc ctttagtttc taaaatcgct
    28141 caaatgtggc tagttggtgc agttgctaaa gtttatgatc catacgttaa gtttgactat
    28201 gttctggacc tggtcggtgg acaaggagtt gggaaaacgt ccctccttca aaaattgggt
    28261 ggcgaatggt atacggatgc cgtaacagat ttctctaata aagataatta cgacattatg
    28321 ttaaagagtc taatcgtcaa cgatgatgaa atggtggcca gtaatcggat gagctttgca
    28381 gaaactaagg cctttatttc taaaactagc ctacgttatc gtaaaccata catgaaacgc
    28441 acagaagagt ttgccaaaaa cttcatttta gctagaacta ctaaccaaac agaatacctc
    28501 aaggacaaaa ccggtgaacg tcgttttcta ccagttatgg cagatagtaa acggcaaaaa
    28561 aaacatccaa tggaaatcga gccagagaca attgaacaaa tctggggcga agccgttaca
    28621 atctatcgtg ctggtgctga tttgatgttt gatgaaaata cagaggatga actgaatatc
    28681 taccgtgaac agttcatgta tcgtgatgaa gttgaattac aagtgcttga atatcttgat
    28741 atgcccgtcc ctgaaaattg gcaaaactgg tctattcagc aacaacatca atacacaagt
    28801 aaatatttcg ataatagtag cgactttgat cctggaagca aaaaactaga taaggtctca
    28861 actcgtgaaa tgatgtacaa cttatttatg agaaattcga atgacaggaa gctgtcaacg
    28921 aagattaaca tgatcatgga taatcatcct gattggaaaa aaagtgtttt ccgggcagga
    28981 ggtaaaagta caaaagggtt cgtaagagtg aaagattcgg aaaaaactaa tcggtagcaa
    29041 ttaaaaaatt atcggtagtc atcggtagca gttgaggggg tagatcggta gcattctacc
    29101 gataaaatga gacatcggta gcagtctaac cccttgatat tactgacttt tatttaatat
    29161 ttatatataa tgctactctt ctacctatat ttttaaaaaa agtatataaa ataatagtaa
    29221 taatagagaa agcctataaa atagggattc tttaaaaata ttttttactt tttagaattt
    29281 atcggtagta cggtagcagt ttgaaaaaaa gaggtaaaaa tgtcatacac agtaacacta
    29341 tattttgaca acatggtaga cgaaactcac ctttttaaga aaaagggtga tgctgcaaaa
    29401 tgcaaggctc agctcgagag caagtatcga ggtgatcgaa tgtataaagt aaagatggag
    29461 gagatggagt aatgagttat gatttggaaa tcttagcgaa aatagagagt ggagattata
    29521 tttgtattgc tgaacctaga tatagttctc cgacctacaa tcttggaaaa atgtttaggg
    29581 tggctatgga ttgggatttc gaccaaggca caatttacaa tgttgctgat atttttgaaa
    29641 atattaaacg tggcataact gaattggaaa ggcaacctga aaaatatgta caatatgaac
    29701 ctgcaaataa atggggaacg atcaatgatg cgttatatgt tttgagatcg ttaagggact
    29761 gtattttaga acaagatatt gatacgaaat atttatatgt gaggtggtaa attgaaacga
    29821 ccaaacagat acccgtacac taaaaatcaa tgggttgaag aaaccgttga tcactatact
    29881 tataaaaacg atatttgcta tacaagtcac attttagaaa atagacttac tggagaaatt
    29941 aaggacaagg agttgaagtg atggaagagt taaagaaaaa agttaatgca gtatacaact
    30001 ggacggtaga agacgggaag ccgcaacctc ccaagcaaaa attaccacaa gcggtgaaag
    30061 accgggcgga ctatttttgg gaaatggcag aagatggtat gacgtttatg ggagcgatgg
    30121 aatgcatctt cgctgatgaa aagcctacag actatgattt gggatctact aaggattggt
    30181 tgccaaaatc taaggagttt gatgattggg ttggctattc gccaagcatg gctcgggtaa
    30241 ttattgcagt ttatttgatt tatagaggaa actaagatga atattaaggc attgattaag
    30301 aagtatgaag aattgtggaa tgaacacagc cctttttatg aacctgtacc ttatacttca
    30361 atggttgaac tttttttgaa agagttgaaa caactagacg aaccccaaaa agtcaaaatt
    30421 ccgcagtttg tggcggaata tatagaattt aaaaagaaaa acaattttca tgtttacggt
    30481 gcaatgagag taattgaaga tcattatgat aagaaagttc ctgattggtt ttacgaaaat
    30541 aacatcgaaa aattctgtct tgcttggctt gacggctacg aggtcgagga agagaagcgg
    30601 tatttggtga ctttaaaaaa taggcagcct ttggtcaaat cgcaatcagg gagtactctt
    30661 tattttagtc aagatataac agctaggaat tataaaggta ctcaaaaaga actagaagaa
    30721 gcaaagttcg gctgggtgtt tgattgtgaa ggaattgata tagaggaggt ggaggaatga
    30781 ttccaaaatt tagagtgtgg gtaaaaatag gaaaacgtat ggttttttca gatgacattc
    30841 ttgctattga ctacgaaaac aaagaaatag tgacacaaca agtttatttt gagaatggtt
    30901 taccagacga tagagatatc tattgttatg attttgacga aatcgaactc atgcaatcaa
    30961 caggactcaa agacaagaac ggcaaggagg tattcatcgg tgacatcgtt aaatgtacaa
    31021 gaggatgtct ccatgaagta tatttagaaa aagaatacgg tggcacattc ataggtggaa
    31081 tgcctgctgt atacctaaaa ggatttggag atggatatgc gtggacggaa tatgaggaaa
    31141 tcatcggcaa catctacgaa aatctagagt ttttggagga aaaagaatga aaccttgtaa
    31201 atatccatat tcaggaagaa gaaaaaagca agaaacaccg tcgccaatat tttctgcacg
    31261 accaattttt aaagaaattc caattgtaga agaagttaag gttgagttcg aagttgaagc
    31321 tagtacaggg cgcatatatc cagaaacgat aatacattta gatatttctg ggtatggaaa
    31381 tagagtgcat tcagtatatc tcttccctgg aaccttactg agtgttggtg agtcaatcca
    31441 actaaaaatg cttttctata gaagacttag aaattttact acagatcgtt ttttgacgtt
    31501 tagggaatct gattggaagt tctttatccg ggacctggtc aacgaattta agcattaaaa
    31561 aaagccaaga cactctctgt ctcagcaata atttcaaaca ctattattat atcacaaaaa
    31621 ggagatagag agtgaacaag gctaaagagt tacttgatga actacagaat ttggatgaag
    31681 agatacagag tcgaatagac gagcttgcta atcttgaagc tagtttgctt tctagtccta
    31741 aaatgagaat ggataaggtt caaggtggtc agaaggttcg attagatgaa cgttacatcg
    31801 atatttttag catgcaagat cccttgaaag agtacataaa gcaagcaact gctgaagcta
    31861 tccagcgcag aattgagctc agtaaattga ttgataaaat gcctaagcct gcaagtcgaa
    31921 caattctaag gatggtgtat attcagaaag caaacgtgta tgatatgatt gaatttttac
    31981 gatgcagcaa gaccactttt tacaaaaaga agaaagatgc aatccgtgaa ttgggtgttg
    32041 tagttgataa aagcgaacta atgtgaacta atgtgaacta ggttgaagcg cactggtcta
    32101 acaatcgtgc tattatagta tcatcaagaa ttaagggtaa ggcagtgagc cttccctgac
    32161 atggagagtt ggcagagtca ggttgaatgc gcccgtttgc tagacgggtg atcgcctatg
    32221 tgcggtccgt gggttcaaat cccacactct cctttgagtg tttgtgtccc agaatggggt
    32281 aggcagtagg cttagcattc atatatcact cattaactcc tatcactcat taacttaaaa
    32341 atggttgcgg aagcgactgg acctcgcatg attgcgtagc taattatatt ccggataagt
    32401 tataagctag agggtttgat tccctcagag gttttaaaga ctacaaaaaa taaaaaagaa
    32461 gtcaaaattt aatacgcacg caaggttgta gtcgccttgc acttttaggg cttagcctag
    32521 ataatctgtg gtaactcagg aaaaggatgt ttttaaatct atcaaacatc ctgccagcaa
    32581 tggtcaatct aagcaatgta atcttaacta tttcagtttt ggaataggta ggcgaagtta
    32641 aagcaggaag attccaacgg caaggtgctg aggaaatgca aatgtggctg tttggctgtg
    32701 aaacgagtct ataagaggaa agaggtattt ggttcgaggt gcaacaagag cttgatacca
    32761 tatcttacaa aaattgggtg cctcccaaaa gtatgtaaga tgagtcgatt gtccgcaaaa
    32821 caatcgataa caagcaggcg ctgtgcattt tgttcttcaa aagagaatga aacacatgac
    32881 gatgcgtgtc tgtgatagat gaaagatgat ttttatattt taaggctatt caagatagaa
    32941 aaaactcaaa aaagcaaaag tcatcgcccg tcgtaaacga aagtgcactt cggcaattag
    33001 attgcctgct caagtctcgc aaggatgaga gtaaagtcaa agagtaaagc agcttagact
    33061 tttagcggag tcttcgttaa ttgaaaaatg gcttagtagt ttgcgatgtg aggagtgatt
    33121 ggtctaacca atcgtgcatg agtgatacaa gtaggaatat ttgtggacaa gataataaac
    33181 tataagttat caaaagtcac tcgtttaaag cagtagtctc atgctagtta atggatacat
    33241 ggtagacgga ttaagtcctg tttagggaat tgaaacgtag gcaggttcga atcctgtcgt
    33301 tccaattgcg attttaattc gcagagagag gtcttgaaaa ggtcgcacat cgtgtggctt
    33361 tttttgattg tttgaaaggt ggtgatggaa aattgaatga aagacaaagg cgttttgcag
    33421 atgagtacat catctcaggt aatgcttatc aatcagcttt aagagcagga tatagtgaga
    33481 aatatgccaa agcaagatct tctgaattgt tggataatgt cggaatttct gattacatca
    33541 aaaatcgaat ggaggagttg caagatgaaa aaatcttaac tcaaaaacaa atacttgtga
    33601 tgctatcaga aattgcgtcg ggacaagcga aagaaacaat agtagtcaca acaaaagtag
    33661 ctgagttgat gactgatccc gtgactggta agtctgtaaa agtctacaat gaaatccctc
    33721 aacttgtcga atacccaaca aagaacagcg ataggaataa agctcttgaa ttgttaggta
    33781 aacgatataa gatgtggaca gacaaagtag aggcagacgt ttctggaacg gtggtgtttg
    33841 caaatgagtc agacatacca gattaagcaa agtgatattg taatcgacct acctaagaca
    33901 gtaggagctg ggtacggaca gttctggcgc tcaagaaatc tttatcgtgt tgtaaaaggt
    33961 tcccgtggtt cgaagaagtc caagacaacc gctttaaatt atgttatccg tcttttgaag
    34021 tatccctggg ccaacttgct tgttattcgt agatactcga ataccaacaa gcaatcaact
    34081 tatacggatt ttaaatgggc gtgtaatgtg ttgggtgtga ctcatttgtt taaattcaat
    34141 gaatctttgc ctgaaataac cataaaagcg actggtcaaa aaatcctatt ccgtggtttg
    34201 gatgatgaac tcaaaatcac atctatcacg gtcgatgtcg gcagtctttg ttgggcatgg
    34261 tttgaggaag catatcaaat tgagactgaa gacaagttca gtacagtagt tgagtcaatc
    34321 cgtggtagct tagatgtacc tgatttcttt aaacaaatca cagtcacatt taacccgtgg
    34381 aatgagaggc actggctcaa acgtgtgttc tttgatgaag agactagccg agctgataca
    34441 ttcgctacta caaccactta caaatgcaat gagtggcttg atggagtcga tatcaaacgc
    34501 tatgaggatt tgtatcatac gaaccccaga cgtgctagaa tcgtttgtga tggtgaatgg
    34561 ggagttgctg aaggtttaat ctatgagaac gtgaccgtca aggatttcga taaggatgaa
    34621 ttgctacgag attcagctaa taagttatgt atcggtcttg actttggttt tactcacgat
    34681 ccaaccgctt tgtgttgttc gttgataaat gacacgacga aagagattta tgtctttgat
    34741 gaggcgtata aagtcggatt gataaccaaa gaagttgcga agatgataaa agacaaaggt
    34801 tatcatcgct cacaaatcat tgctgatagc gcagagtcac ggctgattga agagctcagg
    34861 tcagaacatg gcatatctag aataaaagag agtcggaaag gtaaggatag tattatggca
    34921 ggcgtatcaa aattgcaagg atacactatt tatgtgcatc cagattgtaa aaacatcatg
    34981 gatgaatttt atagttactg ctaccagcga gataaagaag gcaactggtt gaataaacca
    35041 gaggataaaa acaaccactt gatggacgct ttgcgttaca gccttcaatg tatcgaaggt
    35101 gggaaagcaa ccgtccgcag acgttctgat tatggtctat agagaggaaa gacatgtacc
    35161 aatatttaac ctatccacgg gatggatatg atgagggttc tttgaagaaa gacctgattt
    35221 acaaattgat aacgatacat agcactgaag gctcgcattt gaagaagctt aaaagctact
    35281 atttgggtga gcatgctatc ttagaacaca cgagacgcaa cgtgaacgca cctaattaca
    35341 agacggtagc caatcatgcc aaggatatcg cagacacggc tacgggctat tttatgggca
    35401 atcctatcaa gtataacaat actgctgacg gtgatatcga tgaactactt acagcctttg
    35461 atggtgctga gattgaccaa gtagatgctc agaatgcttt gaacatggct atctatggtc
    35521 gtgcttacga gtacatctat gctaaagagg gtatgactga gttggattca actagtattg
    35581 atccggagaa tactttcatg gtctacgatg atagtattga gcggaagccc ttgtttgcgg
    35641 tctattacta tgaagtaaaa gacgatacga aagacactac caagcaccag gctgaggtct
    35701 ttaccgaaaa tctgcactat cacatggtgc tgagaagtac agattcagga acaactcaga
    35761 gcgaggaggc aacacctcac aaccttggtc aaatcccaat tatcgagtat cgcaataatc
    35821 actttgcgat tggcgactac gagcaacaaa ttagcttgat agacgcttat aattccttga
    35881 tggggaatcg tgtcaatgat aaggaacagg ctgtagagtc tatacttgtc ttgtatggca
    35941 cgcagttagc agacactcca gaagacgcta aggtagcaat gaagattctt tctgaagaag
    36001 gtcttttgga attgccgggc gatagtgcaa gggctgagtt cttgaagaat acgctggacg
    36061 aaagtgctac tgaaatcttg cgtacagctc ttaaagagga catctacaca tttagccatg
    36121 tgcctaattt gactgatgag aatttcgcag ggaatacatc aggcgtagcc atggaattta
    36181 agctgatggg ccttgagatg attactaaga ccaaggaagc gaactataag cgaggattgc
    36241 gtcagcgtat tgcgattttt gctcattact tgggtatgaa acagattgca ctagagtctc
    36301 attcaatcgt tccacaattc agccgtggtt tgcctaaaaa cttgctggaa atctctcaga
    36361 ttgtgaacaa tttggaaggt aaagtgacca ataggcagct tatttctctc ttgccgtttg
    36421 tggaagaccc tgacgctgaa ctggaagcct tggaagaaga aaaaaagaag aacatggaag
    36481 acatgccgat gttcaaccaa gaaaacacga aacccgaaga cgaggtagag gatgaagaat
    36541 caggagtatt gggcgaagag gaaagccaat ctgatttacc agcagatgga caaggccgaa
    36601 aagcaggcag accagttcga taaggtctat caggaagcca agacttactt ggataaggaa
    36661 gtcaataaga tttttgataa gttccaacgt gattatggtc taagtcaggt agaagctaga
    36721 caagtattga agaacatgaa agacaagaaa aatctgaatg aacttcgtaa agtacttgaa
    36781 gcgagaccga atgacccgaa catccaaaga ttactagctg acttagacag cccagcttat
    36841 tctttccgta tgaagcgcct agagcgtttg agcgacgatt tagaccgtat gcgtgaatct
    36901 atctatcatt cagagaagac aggctcagac gccttttata gcgacttgat gaaggatagt
    36961 tactacaagg ctacctttga cctgcagcag cagacaggac tagcatatgg cttttctggg
    37021 cttcctgaga acgagattaa acatctacag tcttttagtt gggtaggaga tggaagtacg
    37081 tactcaacaa acatctggaa gaatacaggg aagcttacat caagcataaa agatgaatta
    37141 ctcataagtc ttatgacagg ccgagataca cgagaaactg cacaagcaat tgctgagcgg
    37201 ttcaatgtgg ggcagaacga tgcaaggcgt ttggttcgga cagaatcagc cttttttcat
    37261 aaccaaatgg agttactcaa ctatgaggaa gcggatatag agaagtatat ctttgtggcc
    37321 gtcttagaca agcgtacatc acgcatttgt caggagcatg acaatcaggt ctatgatagg
    37381 gataaggctg tccctggtgt caattgtccg cctatgcacc cttggtgtag gtctactact
    37441 gtcggatacg atgaggacgc agactacagc aagttgaagc gcagagcaag gaatccagag
    37501 acaggtaaag ttgagtacgt gcctgccgat atgacttata aagagtggta tagcaagtat
    37561 gttgcgaaag atgtaaaaaa tgaaatacaa gattataaga aaagtgacaa aaccgtttca
    37621 agatataata ccccaaaatt gttttctgat gttagtaacg catgggatga aattgggagg
    37681 ggtggattat cgaaagaaca acttgtagac ttgctagaat ctgaatatga attaggtaat
    37741 ttttcgagcg atatagcaaa attgatagga gtaagttctg cttatataga tgttagtagt
    37801 ttagctactt cattagtgag acatggacaa cagtattcct tagatgaatt tatgttaata
    37861 aaagaggcgg ttcaaaaacc ttatttgatt ctagataatt cagagagggt tgaaaaatca
    37921 attatttcat atgtaaaaat acctaacaaa gataaggtca ttatggaagc ggtgatggtg
    37981 ccacgagatg aaatgctagt cattcacttt aacaaggtgg ggattcgtca agttaaaaag
    38041 aatgaaaaaa atatgtcgac gctttacaaa aagggaaaat aatgctatac tcttggtaaa
    38101 gatagaggtt gagaatctgt caccaacgcg ccacttatag tgggtcgaga aatgcaggag
    38161 ccccgacagt cctgcctatc tgtgcactaa acaatcgttt agtgcttttt ttgtactcag
    38221 aaaggattga aaatggacac agcaagaatt gggataacta acgtagaatt ttcaggaaca
    38281 ggcgaaaatg actcagcgac agtgaaatta gagttaaata tttatggggc ggatacgttc
    38341 agcgcgattg agttactacc taaaatatta accgacattc attcattatc gtatgaagtt
    38401 gattgattgt gacattaaaa ggagtgaaaa catgtttata tgggattggg tatcaatcgc
    38461 ctttgggtgg ttggtatttt tgttgttaat atttattatt atggccgtaa tcagcggaat
    38521 aattaaaggt gtaaagaaag gaacagaaaa atggaagaat ggaaagaaag atttaaaaaa
    38581 gaatactacg aattgaaaga acgattccag aagttagata tgatgattgg gaaatacgaa
    38641 aaagggcaac tagagtttga atctaaatgt ccgattgatt tgttaaaagg tcagcgttca
    38701 accatgtgga attatttaag aattctagaa caacgtgcaa aaattgaaga aattaaacta
    38761 taaaaattaa ccgcatcgaa atcgaggcgg ttttcttatg ctctaaccgt atggaatccc
    38821 gtacggtttt tatattgtcc aaactgtgcc gatgacatta aaagctgtac tgttccgtcg
    38881 ccggacgtaa agcgagatta tcgagtggcg acgtaatcgc tggaggacaa ttatgtcaga
    38941 agaaatcaat gcaactgtat ctactgaatc aactgagact gtcgacactc aaggaaatgt
    39001 tgattcagtg caggaagaaa agcacgaacg aactttcact cgtgctgaaa tcggtaagat
    39061 gctatctgcc gaacgctcta aatgggaagc tgagcaagaa gccaaggaaa acgaagccaa
    39121 gaaacttgcc aagatgaacg ctgacgagaa acagaaatat cagttggatc agcgtgagca
    39181 agaactagct gaccgtgaga aggctattgc tcgcaaggaa ttgaccgcag aagctaaagc
    39241 aatgctaagt gaacgtgact tacctgttga gttagtaaat gtagttgatt tgacaagcgc
    39301 agagacggta tctgaatcta ttacctctat acaaaaagca tgggaagagt cagttcagaa
    39361 gggagtttct gaacgtatga aaggtagtgc acctatcaaa aatgcacaaa cagtccagca
    39421 agaagtcacg gaaaaatggc gtaaagactt cttgtaataa aagaaaagag gaaaaataaa
    39481 tggcatttga agaattaaac acagcagaat cacgcaagaa acatcttggg attattgagg
    39541 atgtacttgc agtaaattca tattcaacac cacttgtgac atcaagcgat gcagtaacct
    39601 tgcaaggtcg ctcttttaca gtagcaactg gtaacacaac agagttgaaa gactacaaac
    39661 gtaacaaaga caacgaattt gatcacgttg aagttgaaga aaaggtttat acccttgatg
    39721 aagaaaaata ctggggtcgt ttcgtagatc aattggacga acgtgactct aatggtcaag
    39781 tgaatatcaa ttatgttatt gcccgtcagg ctgcagaagt agtcgctcca tatcttgatg
    39841 aactacgttt tggtgcagca cttggaaacg taagtgacaa tgttgccatg ggtaaaacag
    39901 caggagcgaa caacgcttat aatgcggttc ttgatgtgtc tgagaaactt gatgagcttg
    39961 gaattacaaa agaacgcttg ctcttcgtca ctccaagttt ctacaaagcg atcaagtctg
    40021 aaatcgttcg tctaccacat ggtgacgcag ataagaaagt ccttggaaaa ggatatgttg
    40081 gtgaattgga tgattacaca gtctataagg ttccttctaa attcctgaaa ggtgttaatg
    40141 cccttgctac tgctccaggt gttgttacat ctccagtaca agtagataat actaagtaca
    40201 acgataacat tccagggcga tttggcgaat tggtagagca attgctttac actggtgcat
    40261 ttgttcttga acacttcaag aaatacatca tcacaattgc agattctaag cctgctgcta
    40321 aaccatctac tcaaggtaaa gttgtaaacc gtgctaaagc gtggaaaact ggaacaacct
    40381 acaaagaagg tgacacagtt actcatgccg ataaagtcta tgtagcggtt aaggatattt
    40441 ctaattcatc aaccgcacca gacacagata caactaactg gaaagaaaaa actggtaaga
    40501 aataggtccg agttatgaaa tttaaaatca aacaagattt ctatgattgg gaatcaaatg
    40561 tgaaacgact ggcaggagag gaacttgaga ttactgagga gcgctatgct gagctggctg
    40621 acaatattgc cagcaacggt gtcgctatct cagatgttct tgaggaaatc tttcctaaac
    40681 ctgagttctt agaagaggat tgatatgtct atagagttgc tgaagaaatt aacaggcgaa
    40741 gaagatactc agcttctcat gttgctccaa acaagggcta caaatcttat cttgtcagag
    40801 actaatcgca catctttgac acctgcttta agtcttttaa tacctgaggt tgctatcgaa
    40861 ctccacaacc gctcaggagc ggaaggagag cattctagaa ccgagggtgg tatagcagta
    40921 gtctacggag aaaacggcct gtctacggat cttctacagc gaatacgcat gcacaggcta
    40981 gcaagggtgg caggtcatgt ttttgaagca gagtagactg aaaccttatc caatgcgacg
    41041 gtttgaaaag actgtcactg aggaaggtgt cgcgaaagaa gggtatgcca aggaagctga
    41101 gacagtccgc cttgaattgt ggccagctag tagcaagcta caatctgaat tgtatggcga
    41161 gcgtgtcaat gatattttga acgcaaatgc caacaagtca gctactatca aagtaaaaga
    41221 tggtgtgtgt atcgatagtc agacggaagt gactcatagg gttatttcta aaaaggtcta
    41281 cacacatcat caagttttgg agttagagcg tgtcagggct actaggggca gataggctta
    41341 tagctaaatg tagacgattg gctagtaaaa aaactggcga ggatatcgtc ttacgtgcgg
    41401 tgcacaatgc tactataaag gttgtccaag cagatgcaag aagactcgca ccagcgagag
    41461 atggagagct tataactagt atcaaaacta gggcaaaaat ggacggagat aaggctatag
    41521 gcgaagttta caccaacctt aaatacgctc cttatgttga gtttggaacg ggaccaatag
    41581 gacaagctag ccattctggt atttctccag aggtcagcgt gacttacaag tctagtccgt
    41641 ggtatgtaca tgaagaccaa atcaatgtag gaccgtacca ctttcaaaaa atcggggagt
    41701 tctacaagat gtatggtcaa cctgcccagc cttatcttta tccagctttg agagacaatc
    41761 aagagcgtgt gtctaagaat atttcgaatt atgtccgtag aaagataaga gaacaaataa
    41821 aatgattaat atcaagcctg ttatttataa agaattgcaa aaggttgcag ataatgtgac
    41881 cgatacttat cctagcgatt gggagacttt cccagtcgtt atttttttgg aagaacaaaa
    41941 caagccgggt gattggtttg atgaccagga acaaaaatcc tctatccgct acaaggtgga
    42001 tatctttgat gatactagca ctagtgagtt agctgttaaa atcaatcaga tttttgagtc
    42061 tttaggtttg cgaagaactg actgccaaga cgtgccagac ccgtctcatt tgagacataa
    42121 ggtcatgcgt tttgaaggta tcgtcgactt acactcagag cttgtttttc aatttagaat
    42181 ggagaattaa acatgttagc aaatggaatt acgctttctt atggcgaaac aaaagatagc
    42241 tatactaaac ttgttggatt gaaagaagta ccagagtttg gtattgaact cgaaaaagta
    42301 gaaaatacta ctcttgaaga tacggtgaag aagtacgagt ttggtattgg ggacatagga
    42361 gaacttgagt acaagttctc ttataataat tcaagcgcaa ctgctcctta tcgtgtattg
    42421 cgtaaggcag cagacgacaa gaagaaactc tactttgaac aagcttatcc agacggtact
    42481 aaggtcattt ttgaaggcca agtatctgtt aagcttggcg gtggcggtgt caatgccgtt
    42541 atcgatttca cacttaagat tgccttgcag tctaatctta catttactga tggtattgga
    42601 ggttaattaa atggcgttaa aatacacaac ttggaaagtt actgacgaaa aagagttgaa
    42661 gctacgtttg acatctcatc aagctgcaac tgtggaagaa aaaatcggca tgaacttgct
    42721 gaagattttc atgcctgaag ctggcgaaga gttcacttta ccgcctttga aagttatgtt
    42781 gttgttagtt cacggagcct tgcagcagta tgaacatggg tattctcttg aggatgtcta
    42841 tgatttatac gatgaatacg tggacaatgg cggagaccaa acaaccttca tgacagaggt
    42901 gttgatgcca ctctttgaag tatcgggttt tactccacga ggaagcaagg acaagaaaac
    42961 ttccaagaag aaaatgacag tagacaagta atcttaacgg taactcagat tattgagagg
    43021 ctttatccta tgtttttgga catcgggggc aagcctcttg atttttggga tttgacggta
    43081 cttgaaatca gagaaatgat tgaaagctat aaccgtgtca aaatccaaga gcgtaaagaa
    43141 aagattattg actcatacag actttcgcag atgatatcca accacgtttc tttattgtta
    43201 tccaaagatg ccaaggcctt tgagttctgg gaatatgcgc ctgagttgtt tgtagaagaa
    43261 caacaagcag tagaacagga acgacagaaa caagcacttt tgttgcataa ggaacggatg
    43321 cgtgaatttg cagagagaca taatcgaaaa aggaaggagg aagtaaatgg caactcttga
    43381 tgaattgaaa gtcatgattg acgctgagat agcgcctttc aggaagaaga tgaaagaagt
    43441 cgagaatcag gtcaaaggaa catctgacca agtgaaaaat gctactgcca aagttcgtga
    43501 acagtcgagc tcaatcggta gtgcgtttgg caagctggct aagttcgctg gttttgcaat
    43561 ccttggtaag aaattacttg atgttgggat gtattcaacg cagacggctc ttgaagtatc
    43621 agcgtctatg aaccaaatca agcgacagat gggcgagagt tcgcaatctt tcttaaaatg
    43681 ggttaacgat aatgccaacg ctatgaatat gggtgtgggt gaggctacca actacggtgc
    43741 agtctactca aacttatttt ctggatttat caaagatacc aacaagctaa gcgcctatac
    43801 cgctaagatg ttgcagacat cggcagttgt tgctgaaggt tcagggcgca cgattacaga
    43861 cgttatggag cggattcgct caggtttact agggaacacc gaagcgattg aggacctagg
    43921 aatcaacgtc aacgtggcta tgattgagtc cactgaagcc tttaagaagt tcgcaaacgg
    43981 acagagctgg caacagttgg attaccaaac ccagcaacaa atccgcctta tggctattct
    44041 ggaacaggct acagccaagt atggggatac cttgtctaat tctgtaaatg gtcgtatcag
    44101 cctatttaag tcgctgatga aggacgcagc attgaacctt ggtaactcta tgttaccgat
    44161 tatcaatgcc attatgcctg tcttgaactc ttttgctatg gtcttaaaga acgttactgc
    44221 taaactcgct gagtttatcg ctttgatgtt caacaagaaa gcaacagtga aagatggtgt
    44281 tggtggagca gttggagaca tgggtaacgc catgaaggat gctgcaggcg gagcaggaga
    44341 ccttgctgac gcagtagacg acgctggaga ttcagcagga ggacttgctg acaatcttgg
    44401 agactccgcc aaaaacgcta agaaggccgc taaagagttg ctaggtcttt tgggatttga
    44461 tgagattaac atcttgcaaa aaccaaaaga tgacgacgca ggcgggtctg gaggcggtgg
    44521 caaaggtggt aaaggaaagg gaggcggtgg cggacctttc aaagacatct tgccagaagt
    44581 cgagttgacc gacatggaca acaaattcaa gagcattttt gatggtcttg gagataagct
    44641 caaagggttg tttgacctct tcaagaaagg ttttgatgca gcatttagac cagaaggtat
    44701 agaacgcatt aagactgcct tagaccaaat agctaagaca atgggagaaa tcgccactga
    44761 cccaagggtt gtgaatgcct ttaaccgaat ggctgagaaa attgcttatg ctttagggca
    44821 agtgacaggc tcaataacaa ctatcgggct aggtatcggt gttttccttg ccgaaagtat
    44881 tgcaaatggc cttggaaggc aaaaagaacg cattaccagg gcgctagtcg ctttgtttga
    44941 taatattggt aacatttccg aggcagtagg aaacatcgct caggactttt ctagtacttt
    45001 ctacgacgtc attacctcaa ctggtgcggt tcgtatcggt agcgctattg tgtcaactct
    45061 gttgagtttg acatctacca ttgttgaagt tggtagtaaa ttagcaggaa gtttgtttaa
    45121 aggttttgaa aaagtcgttg tgacaagcgc tcctaaaatt tcatcagtct tccaaagttt
    45181 attagatact gttgcgcctg tatttgagag cattgaaagg tctgttaaca aatttggcga
    45241 tggcttaagt cgtgtttatg atgaacatgt agcccctgct attaactcta ttgctaatgc
    45301 ttttaacgga ctgattgata tcatacaaat cctctgggag aattcttggc aaccttttgc
    45361 tgagttttta tcaggagtat tcggtgttag tattgaagga atttcagatt tattaggagg
    45421 tggcctttta gccactttgg gactattggc ggatgctatt aagttagtgg cagatggttt
    45481 caccgttttt tctgactggt gtaaagaaaa caaagaacct atcttggctt tgataacaac
    45541 ttggcaaacg attaatttct tatcatgggc tgaacaagcc gggggacttg caggagcatt
    45601 cagcttgtta ggtagtaagg tctctttgat tgttggaggg attaagaatc taggtcttgc
    45661 tattaaagca ttgacatttg ataagttggt cagttttggt gaaacaatct atttgaacac
    45721 cttatatgca aaagattttg tggtcaattc aggtaaaaca attgcacagc taggaaaaac
    45781 tgctttagaa cttggtaaat cagctctagc atggactgct catgcagcga aaatgggatt
    45841 agcaaccgcg gcggaatttg cacattctgt tgcagcagga gtcgctacag ctgcaacatg
    45901 ggcttttaat gcagcgttag cagttttgac aagtccaata acatggatta ttgcagcaat
    45961 cgcagctttg attgctatcg gtgtcttgct ctaccaaaac tgggacactg ttgttgagtt
    46021 tgctaaaact gcatggcaag gactatgtga ttttattagt ggtatttgtc gagctattgg
    46081 cgaatttttc agtggtctat ggacaaaact acaagaaatc tttgagccga taggtcaatg
    46141 gtttggcgag aagttccagc aagcatggga tgccattgtc aacatcttct ctggtatcgg
    46201 agagtggttc tctggtgtat tccaaggtgc atgggacgct atcgttaata tcttcactcc
    46261 aatcggctca tggtttggac aacgttgggc agatgtgact agtgctttgg ctaatatcgg
    46321 ggcatggttt actgacatat tccaaaaagc atggactggt ctaacaaaca tctttagcaa
    46381 actaggttta tggtttggcg agagatgggc agatgttaca agtgttcttg cgaatgtatc
    46441 ttcttggttt gggaatatgt ttactagtgc ttataatgca gtcaagaacg cgtttagttc
    46501 aattggtggc ttcttcagcg gtgtatggtc aacggttcaa agcatatttg tcaatgctgg
    46561 acaaaaggtt ggtagcgctg taggtggagc gtttaagagt gcggtcaatg cggttcttgg
    46621 aacgattgaa aatgtagtca atggcttcat cggaatgatt aatggagttt taggcgttgt
    46681 cagaaactta cctggtctag gatgggttgg tagtgtaagc acagttagcc tccctcgtct
    46741 tgcccgtggt ggtatcgtcg atagtccaac aatcgccatg attggtgaag ctggtaaaga
    46801 ggcggtcgta ccacttgaaa atacaggatt tatccaaaca cttggacgag tagtcagcag
    46861 tgcggtagta aatgccatgg ctggtattag tccacaaggt ggtttttcta gcgacggcga
    46921 catcgttatt caaatcgcag gccatgagtt cggacgggta gctatccaag aaatcaacaa
    46981 ggaacatgaa cgagcaggtc aaaccttgct caagatttag gaggttaaat ggcacaattg
    47041 acaatcaatg gggtggctgt gaagcctccc aaatcttttc aagtcggtat tcaagatatc
    47101 gatggagaga cagggcgtaa tgccaatggc gacatggtgc gtgaccgtat cacgaccaaa
    47161 cgcaaactag actgtgaatg gggtatgatg actcagggag aaataagtca gcttttacat
    47221 gctgtatcat ctaaattttt tgaggtatct tatccagacc ccatggatgg ccaagtcaca
    47281 aagactttct atgtcggtga taggacagct cctagctata cctttactga gaagcttaaa
    47341 ccttggtctg gcgctaaatt taatctggta gagaggtaag aaaatggacg ctttaactag
    47401 acgacaattt gacagagcca tgtttgccaa ggaaaggacg ctggctattc gtgttggtga
    47461 atatgcttca cgggatatca aagaggctag ttttgagtat ggctacatca agggcgatac
    47521 ttataagcct ggtggaacct gcgctggtag cggtaaaatt acctttacca gtatcattac
    47581 cacgttcaat aagctggata ccctgcaccc tgagattggt ctactggttg gggataccta
    47641 ccagtgggtc aagatggggg aatacttcat caacgatatt gagattgacc gaaaccgcaa
    47701 cacaaccaca cttgaactta tggacggtat gtttaagctc aatcgtgagt acgtgacgga
    47761 tttgcatttc ccagctgaag tacgagaggt tattcaggaa atctgcctga aaacaggcat
    47821 tgagttagcg aatgactatt tcggaatcag cgctatgcgt taccatatcg agcaagttcc
    47881 tgaaggtaag aaactttcgt tcagggatat gctgagcgct atgactcaga tgattgggat
    47941 gtcttgcttc ttcaaccgag aaggaaagat ggaaatccgt gatttgaccg agtccaacat
    48001 cacgattaac gctgacagtt acttcttgca tggattgacc aagagtgaaa tcgagtatca
    48061 gatagctggt atcacttgta agacggataa gaagtctctg acggtcggta tgacaacagg
    48121 tcggtctttg gaacttgata atgtcttcat aacccagagc gctttaaatg acttgtatta
    48181 caaactgaaa aacctaactt actatccgta taatctcaac taccaaggac atttgttact
    48241 tgaggttggg cagtgggtaa ccattcagac caacaagaaa gagactttta aagttcctgt
    48301 cttaagtcag agctttatct ttaaaggtgg tctgagaggt cgtatcagtg cagatagtaa
    48361 ggctggaaac gatacccagt attcttacga gggtacgatt accaagcaga ttaagcaaca
    48421 agatggcttt gaagcgaaaa tccaagcgca gattgaagca gcagataaag attttgacca
    48481 aaaggtcgac aaaatcaaaa aagactttaa cgatcaagta gaactggcca aagccagagc
    48541 tgaagaagtc aagagagaac tgtctgacac tatcaatcag cgctttaata gctttgacaa
    48601 cgggccattg aaagaagcta agcgcaaggc tgaggaagct ttgcgaaatg ctggcgcaag
    48661 tagttctctt gctcaggaat ccaagcggat tgggctggat tctgttgcta gacttgaagc
    48721 gtttaagtcg cagactacga gcgcacaaac ggctctgtcg ggtgacttgg acgctctgaa
    48781 acggactatc gcgaatgata ttcgaccgaa gcaagcacag gctgaagctg agattgccaa
    48841 gcaagttgaa gcacttagcc ggactaaaaa tgaactggat ggcgtgaagt cagcgcaagc
    48901 gacgtatgag gagacgacga ctcgtagact gtcagaactg accaacttgg ccaatggtaa
    48961 agccagcaag tcagaactca cgcagacagc tgaggagctc tctagtaaga tagcgagtgt
    49021 gcaggttggg ggaatcaacc tcttgcgtaa tactgcgagt ttgttgattg gcgatcgttc
    49081 aaaaggatgt tggatgagtt caagcggagg aaatgggcga gcgattagcg tagaagtttt
    49141 ggctcctccc aaaaaaatga taaaaaacat gattcgtgtt attgaaaata cgaatggtgg
    49201 aaataaagat ttaactcaac ttgttagatt gcgaattggt gaaaagtaca cgatttcttg
    49261 ttatgcaagg gttgctagcg atagcccaaa tgcaaacgtg aacttgctat ttcgttcgtg
    49321 ggcaaataat accgatttaa atcgcaaatt tcagaaatcc atctctcata aaaattggca
    49381 aaaatattca tttacattta ctgctgatgc aattgaaaat tcaattcaat ttggacaatc
    49441 tggcgcagga attatcgaaa tatgcgctcc gaaaatcgaa tcaggaacgt tagcgactga
    49501 ttacagcgaa gctcctgaag atatagaagg tcagatttca acagttgaat cgaccttcaa
    49561 acaacgagcc aactcgctcg acgctggtgt aagccgtctg actgaagggc ttagaactaa
    49621 agtggatatc agcgcactca acgtgactgc tgaaaatatt aggcaatctg tgaagagtct
    49681 tgagacagac acgcagaaca agctaaatca gaagttgagt caggctgaat ttgaggtgcg
    49741 agccggctct atccgtcagg aaatcctgaa cgcaaccaag gataaagcag ataagacttt
    49801 agttgtatct gaagctggga aattgcgtga agaattttca aaaatgaagg tgggaggacg
    49861 gaatctatgg ataaaatcca agacggttgg agctgtaatt gaaaaattac ctgaaaacca
    49921 cgtcacaggt caaaaagaat gctataggct agagaacaac tctactttaa cgttcaacct
    49981 tgaaccagat ttcagctcaa ggttgtacca aaaagttact tttagcgctt ggatcaagta
    50041 cgaaaatgta gtccaaggtc gaaatttttg gaatgtattt aattgcttca aacattatct
    50101 ttttagaaaa aatagtgaga ccggagtaca gagtggtcca gattatgcta cgcttggtat
    50161 gtataaaggt tcggcagatt ggaaatatat tacattcact tatgactact ctgaaaaaac
    50221 aaattttgat caattgaaga catcattgcg attcaatctt gaaggtgcta caagcggtac
    50281 agcttgggta acaggaatca aggttgaaat cggtagtgtg gcgacggact ggagtcctgc
    50341 gcctgaggac gctgatggtc tcattactga agctaaggct acctttgagc ggacagctca
    50401 gggcttgcga accgacttat cagctattca ggaatatgta aataaagacg gtcagcgaca
    50461 ggaagcccta cagcgctata ctcgtgagga gagcacgaga caagcgacag cagtccgtga
    50521 gctggtcaat cgtgatttcg ttggtaaggc tacttatcaa gaagatgtta agggtatcaa
    50581 tcagaggatt gaagctgtta aaactagtgc gaataaagac atcgctagtc aaatcgctag
    50641 ctatcgtcaa tctgtagatg gtaagttcac ggatatttca agtcagataa ctacttataa
    50701 gcaagatgtg ggcggtcaaa tcagtggtct ttcaaataga cttacaagca gtgagcaagg
    50761 aaccactact cagatttcaa atctttcaaa tcggataaac agtaataaac aaggcacaga
    50821 taatcagatt tcaaatttaa agactcaggt cgctacaaac aaggataatg ctgaacgaca
    50881 aatgggtaga atatctgatc aggtttctgc aaacaaagcg aatgctgata gtcaatttgc
    50941 gaatgtgacc aatcaactag tgcgaaaagt agagactact gacttccagc gtgttaagga
    51001 aaccagtaaa ctttacgagc ggattttggg caatactgaa aatggaattg cggataaggt
    51061 tgctcgcatg gctctgacca atcaactgtt tcaggttgag gttgggaaat atagtgtaag
    51121 cggccctaac ctcattaaga atagtgattt taaaaatgct acgaatgaat ggggctcaac
    51181 tcaaaattta ggaagattgg ttaagcatag cttttatcac aacgggcaga aagaccttat
    51241 gcgtttaagt aatgcaacta aaaacgaaaa ctttttgtat agtcaccgtt ttaatcttga
    51301 acgaaatact gactatgtac tgaattttag aggatttaac aacagtgctc tagcaagcta
    51361 tgatgtttat attttgggac gaagagcagg cgagagcgat ggattcacaa tcgttaagaa
    51421 agttgttagc agcaagaaac tatctacctc tagatgcgaa gatgtctcag taacttttaa
    51481 ttccggagaa atggataatg cttacattcg ttttgataac aatggctcat catcaggaac
    51541 agctgatttg tatattacag aagttgactt gtacaaaggt tataaaccta gaacatggca
    51601 accacatcca gaagatgcag tcgcagatgc gaataagaag cttgaagcaa cgcaaacaaa
    51661 aatgactcaa ctagctggct catgggtagt tgaaaacatc aactcggctg gagatatcat
    51721 ctctggaatc aatcttggcg ccaatggaca taaccgcttc gttgggaaat tgacccacat
    51781 cactggagag accctgattg acagagcagt catcaagtct gccatggttg ataagctgaa
    51841 aacgggcaat tttgaagctg gttcggtcac gactacgata ttagacgctg aagcggtaac
    51901 tgctgagaag ttgaaagttg acgatgcgct tattagaaaa atgactgcaa atgacgcttt
    51961 tattgaccga ctgacatcta aacgtatctt ctctactaag gttgagtccg tcatttctag
    52021 ttcaaccttc ctagaagcct atcaaggtcg aattggtgga ttcacacttg gtcaatttga
    52081 ccagggtggc ggtcgctgga tttcaggtgt caatcagttc tctgttggta tggggaatgg
    52141 tgccgggcat ggagtccgga cagccttctg ggcgaactgg ggaaataatt ggaactatgc
    52201 cgggcctaaa gcatggaacg tcaatactga tgggaaaatg tactgtagga atgaagtcgg
    52261 tttttatgat caagtggatt tttcgaattc atcgagagca aacttctatg ggaatactac
    52321 tttttctcgt tctcctgtgt tttcaaatgg tatcgaactt ggaagtaaag atgtgcttgg
    52381 tgatggttgg aatcccaaag gcggaaggaa tgcggttgtt tggtggaatc aggtcggtag
    52441 cggtagcgtg aagtattgga tggaacaaaa atcagataga cgcttaaaag agaacatcac
    52501 agatacagct gtgaaagcct tggataaaat caacagatta agaatggttg catttgattt
    52561 catcgaaaat aagaaacatg aggagattgg tctaatagct caagaggctg aaaccatcgt
    52621 tccaagaatt gtctcacgag atcctgagaa tccagatggc tatctgcata tagactatac
    52681 cgctttagtt ccttacttaa tcaaggctat tcaagaatta aatcaaaaaa tagaaaaaat
    52741 ggagaaaaca atagcatgaa taacaacatg ttgaccaata tcgcacttaa agcaattcag
    52801 gagcttgctc ttgaaaatag aaaacgaaca cacagattgg agaacttaga aaatgaacac
    52861 agaacagctt aaccaagcct tacaaatgac aattagtgaa atgtcaacaa cttcaacaaa
    52921 ttcgatgatt gcaagtaata tcttgagtat tcagttgaat gagcaaaggg aagagaatca
    52981 aagacttcaa gcacgagtgg atgagctgga agctctgctt gatgaacaaa ctaaaccagc
    53041 agacaaagga gaatagacat ggcagaaaca attcaaaaca cagataactt actagacctt
    53101 acaaaaatca cagaaccatt tgatcttgcg agtgctttgc gctacatgaa agaaaatgga
    53161 gagttcattc gttgcaagaa tgtaagcgat gacttctata tgtatcgtga cgttcaaaaa
    53221 cgtcctgtga tcgtaaatgg ccgtcgccaa ttaaaggatg ttgaaaccgt ttgggcgttc
    53281 aaccagtggg gtggtacaat cgcaacaatc aacgtagccg ttctgttgaa tcatgaattc
    53341 tatatcatga aatttgatgc agagggcaat cctgactgga cggatccaac ggtaaaacct
    53401 aaagaatagg aggtgtgtat gcaaattgaa tttttcaatt ttctaagaag tgtcgtacag
    53461 actgaagatg gtttggtctt gtacgctcta acactgattg tctcaatgga aatcattgat
    53521 tttgtcacag ggacgattgc ggcgattatc aatcctgaca tcgagtacaa gagcaaaatc
    53581 ggcattaacg ggctccttcg taagatttca ggggttctct tactgatgat cctcattccg
    53641 gcgtccgttt tgttgcctga aaagacaggt tttgtattct tgcattcaat ctgtctcggg
    53701 tacatcgcat ttacttttca atctctcatt gaaaattacc gcaaattaaa aggaaatgtt
    53761 actctttttc agccgattgt aaaagtattt cagcgattac ttgaaaaaga tgatgatacg
    53821 aaaaaaggag aataacaaat gcaacaaatt actgaaatca ttactaatgg agcaatcagc
    53881 atcctagtcg ttttggcagg ggttgtagtt agggcagtca aggactacct ggttcaaaaa
    53941 ggtggagaaa agaccatcaa gattgttgaa atcttggcca aaaatgcagt aaatgccgtg
    54001 gagcaggtag ctgctgaaac tggctacaag ggagatgaaa aactggcaca ggctcgcgct
    54061 aaagtccgtg ctgagcttac aaaatacaat attagcatga ctgacaaaga cttagacacc
    54121 ttcgtagagt cagcagtgaa gcagatgaat gacgcatgga aaggacgata gggaatggat
    54181 atcgatagaa acagactacg tacaggcttg ccacaggttg gggtgcagcc ttatcgacaa
    54241 gtacatgctc actcaacagg taaccgcaac tcaaccgtac agaatgaagc ggattatcac
    54301 tggcggaaag acccagaatt aggttttttc tcgcacgttg ttgggaacgg ccgcatcatg
    54361 caggtaggac ctgtgaacaa cggaagttgg gatgttgggg gcggttggaa tgctgagacc
    54421 tatgcagcgg ttgaactgat tgaaagccat tcaactaagg aagagtttat ggctgactat
    54481 cgcctctata tcgaattgct acgcaatcta gcggacgaag caggcttgcc gaagactctt
    54541 gatacagacg acttggcagg tatcaagacg catgaatact gtaccaataa ccaaccaaac
    54601 aaccactcag accacgttga cccttatcca tatcttgcta aatggggcat tagccgtgaa
    54661 cagtttaagc aagacatcga
//
LOCUS       DAVLXH010000007        54405 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00028199
            SAMN33607166-rid17955573.denovo.007, whole genome shotgun sequence.
ACCESSION   DAVLXH010000007 DAVLXH010000000
VERSION     DAVLXH010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607166
            Sequence Read Archive: SRR23725544
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 54405)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 54405)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721421.1
            Genome Coverage       :: 115x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:42:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,210
            CDSs (total)                      :: 2,161
            Genes (coding)                    :: 2,023
            CDSs (with protein)               :: 2,023
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 73 of 138
            Pseudo Genes (incomplete)         :: 60 of 138
            Pseudo Genes (internal stop)      :: 40 of 138
            Pseudo Genes (multiple problems)  :: 31 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..54405
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607166-rid17955573.denovo.007"
                     /strain="AUSMDU00028199"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1349"
     gene            complement(186..896)
                     /gene="treR"
                     /locus_tag="VYO11_000486"
     CDS             complement(186..896)
                     /gene="treR"
                     /locus_tag="VYO11_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HEV1595090.1"
                     /translation="MKKYQQLFKQIQETIQNETYAVGDFLPSEHDLMEQYQVSRDTVR
                     KALSLLQEEGLIKKIRGQGSQVVKEETVNFPVSNLTSYQELVKELGLRSKTNVVSLDK
                     IIIDKKSSLITGFPEFRMVWKVVRQRVVDDLVSVLDTDYLDMELIPNLTRQIAEQSIY
                     SYIENGLKLLIDYAQKEITIDHSSDRDKILMDIGKDPYVVSIKSKVYLQDGRQFQFTE
                     SRHKLEKFRFVDFAKRKK"
     gene            1081..3048
                     /gene="treP"
                     /locus_tag="VYO11_000487"
     CDS             1081..3048
                     /gene="treP"
                     /locus_tag="VYO11_000487"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HEV1595091.1"
                     /translation="MGKFEQEAKDLLQAIGGKENVTAVTHCATRMRFVLGDDKKANVK
                     AIESIPAVKGTFTNAGQFQVIIGNDVPIFYNDFTAVSGIEGVSKEAAKSAAKSNQNVV
                     QRVMTTLAEIFTPIIPALIVGGLILGFRNVLEGVHWSMLDGKTITESSQFWAGVNHFL
                     WLPGEAIFQFLPVGITWSVSRKMGTSQILGIVLGICLVSPQLLNAYAVASTPAADIAA
                     NWVWNFGYFTVNRIGYQAQVIPALLAGLSLSYLEIFWRKHIPEVISMIFVPFLSLIPA
                     LILAHTVLGPIGWTIGQGLSSVVLAGLTGPVKWLFGAIFGALYAPFVITGLHHMTNAI
                     DTQLIADAGGTALWPMIALSNIAQGSAVFVYYFMHRHDEREAQVSLPATISAYLGVTE
                     PALFGVNVKYIYPFVAGMTGSALAGMLSVTFNVTAASIGIGGLPGILSIQPQYMLPFA
                     GTMLVAIVVPMLLTFFFRKAGLFTKTEGDTNLQAEFVAQEEAEFVNHEPVELTSVEII
                     SPLTGQVKELSQATDPIFASGVMGQGLVIEPSQGELTSPVNGTVTVLFPTKHAIGIVS
                     DEGVELLIHIGMDTVGLDGKGFESLVVQGDHVTVGQQLIRFDMDVIKAAGLVTETPVI
                     ITNQDAYTATIPGTYPTTIQAGASLMVATRI"
     gene            3226..4851
                     /gene="treC"
                     /locus_tag="VYO11_000488"
     CDS             3226..4851
                     /gene="treC"
                     /locus_tag="VYO11_000488"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HEV1595092.1"
                     /translation="MTLDKGKVVYQIYPKSYKDTTENGIGDFRGIIEKIPYLAKLGVD
                     MVWLNPFYPSPQRDNGYDISDYMAVDPLFGDMADFEEMVCVGKEHKIDFMLDMVLNHC
                     STEHEWFQKALAGDKYYQDFFFIQDQPTDWQSKFGGSAWTPFGDTGKYYLHLFDETQA
                     DLNWRNSNVRKELFKVVNFWRDKGIKGFRFDVINLIGKDEVSVDCPENEGKPAYTDKP
                     IVHNYLRMMNQATFGSDDSFMTVGEMSSTTMENCVLYSSPDRQELSMTFNFHHLKVDY
                     KDGQKWTLAPFDFEELKSLYHSWGKEMSDKDGWSALFWNNHDQPRALNRFVDIQNFRK
                     EGATMLAASIHLSRGTPYIYMGEEIGMIDPDYDSMADYVDVESLNAYQTLLEEGKSQQ
                     EAFQIIQAKSRDNSRIPMQWDASENAGFSTGTPWLKAGKSYKYINVENEIQGPIFTFY
                     QDLIRLRKEMPIISEGSYKPAFEDSKQVYAFERQFEDQKLLVLNNFYAKEVEIDLPAV
                     YQNGQILISNYEDAEVSEKILLKPYQTLAIYVN"
     gene            5107..5355
                     /locus_tag="VYO11_000489"
     CDS             5107..5355
                     /locus_tag="VYO11_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000364981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HEV1595093.1"
                     /translation="MDLLLAIVLIVLAFLGGALGGMYLVRKQIEKEFADNPRLNAEAV
                     RTLLSANGQKPSEAKVQQVYHQIIRQQKAALANNKKKK"
     gene            5562..6356
                     /gene="racE"
                     /locus_tag="VYO11_000490"
     CDS             5562..6356
                     /gene="racE"
                     /locus_tag="VYO11_000490"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000370386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HEV1595094.1"
                     /translation="MDNRPIGFLDSGVGGLTVVRELMRQLPHEEIVYIGDSARAPYGP
                     RPAEQIREYTWQLVNFLLTKDVKMIVIACNTATAVVWEEIKAQLDIPVLGVILPGASA
                     AIKSSQGGKIGVIGTPMTVQSDIYRQKIHDLDPDLQVESLACPKFAPLVESGALSTSV
                     TKKVVYETLRPLVGKVDSLILGCTHYPLLRPIIQNVMGPKVQLIDSGAECVRDISVLL
                     NYFEINRGRDAGPLHHRFYTTASSQSFAQIGEEWLEKEIHVEHVEL"
     gene            6353..7324
                     /locus_tag="VYO11_000491"
     CDS             6353..7324
                     /locus_tag="VYO11_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000182414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-triphosphate diphosphatase"
                     /protein_id="HEV1595095.1"
                     /translation="MTNKIYEYKDDQDWYVGSYSIFGGVNSLSDYQTDFPLFEFSKIF
                     GDEEYGFPLSVTVLRYGSTYRLFSFVVDMLNQEMGRNLEVIQRHGALLLVENGQLLYV
                     ELPKEGVNVHDFFETSKVRETLLIATRNEGKTKEFRAIFDKLGYDVENLNDYPDLPEV
                     AETGMTFEENARLKAETISQLTGKMVLADDSGLKVDVLGGLPGVWSARFAGVGATDRE
                     NNAKLLHELAMVFELKDRSAQFHTTLVVASPNKESLVVEADWSGYINFEPKGENGFGY
                     DPLFLVGETGESSAELTLEEKNSQSHRALAVKKLLEVFPSWQSKPSL"
     gene            7300..7821
                     /locus_tag="VYO11_000492"
     CDS             7300..7821
                     /locus_tag="VYO11_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001118598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HEV1595096.1"
                     /translation="MAKQTIIVMSDSHGDSLIVEEVRDRYVGKVDAVFHNGDSELRPD
                     SPLWEGIRVVKGNMDFYAGYPERLVTELGSTKIIQTHGHLFDINFNFQKLDYWAQEEE
                     AAICLYGHLHVPSAWLEGKILFLNPGSISQPRGTIRECLYARVEIDDSYFKVDFLTRD
                     HEVYPGLSKEFSR"
     gene            7818..8279
                     /locus_tag="VYO11_000493"
     CDS             7818..8279
                     /locus_tag="VYO11_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000560721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEV1595097.1"
                     /translation="MIAKEFETFLLGQEETFLTPAKNLAVLIDTHNADHATLLLSQMT
                     YTRVPVVTDEKQFVGTIGLRDIMAYQMEHDLSQEIMADTDIVHMTKTDVAVVSPDFTI
                     TEVLHKLVDESFLPVVDAEGIFQGIITRKSILKAVNALLHDFSKEYEIRCQ"
     gene            8270..9010
                     /gene="xerD"
                     /locus_tag="VYO11_000494"
     CDS             8270..9010
                     /gene="xerD"
                     /locus_tag="VYO11_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HEV1595098.1"
                     /translation="MPMRDRISAFLEEKQGLSVNSKQSYKYDLEQFLDMVGERISETS
                     LKIYQAQLANLKISAQKRKISACNQFLYFLYQKGEVDSFYRLELAKQAEKKTEKPEIL
                     YLDSFWQESDHPEGRLLALLILEMGLLPSEILAIKVADINLDFQVLRISKASQRRIVT
                     IPTALLSELEPLMGQTYLFERGGKPYSRQWAFRQLESFVKEKGFPSLSAQVLREQFIL
                     RQIENKVDLYEIAKKLGLKTVLTLEKYR"
     gene            9010..9738
                     /locus_tag="VYO11_000495"
     CDS             9010..9738
                     /locus_tag="VYO11_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000351912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HEV1595099.1"
                     /translation="MDIKLKDFEGPLDLLLHLVSKYQMDIYDVPITEVIEQYLAYVST
                     LQAMRLEVTGEYMVMASQLMLIKSRKLLPKVAEVTDLGDDLEQDLLSQIEEYRKFKLL
                     GEHLEAKHQERAQYYSKAPTELIYEDAELVHDKTTIDLFLAFSNILAKKKEEFAQNHT
                     TILRDEYKIEDMMIIVKESLIGRDQLRLQDLFKEAQNVQEVITLFLATLELIKTQELI
                     LVQEESFGDIYLMEKKEESQVPQS"
     gene            9757..10326
                     /locus_tag="VYO11_000496"
     CDS             9757..10326
                     /locus_tag="VYO11_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein B"
                     /protein_id="HEV1595100.1"
                     /translation="MSTLAKIEALLFVAGEDGIRVRQLAELLSLPPTGIQQSLGKLAQ
                     KYEKDPDSSLALIETSGAYRLVTKPQFAEILKEYSKAPINQSLSRAALETLSIIAYKQ
                     PITRIEIDAIRGVNSSGALAKLQAFDLIKEDGKKEVLGRPNLYVTTDYFLDYMGINHL
                     EELPVIDELEIQAQESQLFGERIEEDENQ"
     gene            10313..11035
                     /locus_tag="VYO11_000497"
     CDS             10313..11035
                     /locus_tag="VYO11_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEV1595101.1"
                     /translation="MRINKYIAHAGVASRRKAEELIKQGLVTVNGQVVRELATTIKSG
                     DKVEVEGQPIYNEEKVYYLLNKPRGVISSVTDDKGRKTVVDLLPNVKERIYPVGRLDW
                     DTSGVLILTNDGDFTDEMIHPRNEIDKVYVARVKGVANKDNLRPLTRGLEIDGKKTKP
                     AVYEILKVDPVKNRSVVQLTIHEGRNHQVKKMFEAVGLQVDKLSRTRFGHLDLTGLRP
                     GESRRLNKKEISQLHTMAVTKK"
     gene            11035..11277
                     /gene="yidD"
                     /locus_tag="VYO11_000498"
     CDS             11035..11277
                     /gene="yidD"
                     /locus_tag="VYO11_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HEV1595102.1"
                     /translation="MKRILIAPVRFYQRFISPVFPPSCRFELTCSNYMIQAIEKHGFK
                     GVLMGLARILRCHPWSKTGKDPVPDHFSLKRNQEGE"
     gene            complement(11502..12467)
                     /locus_tag="VYO11_000499"
     CDS             complement(11502..12467)
                     /locus_tag="VYO11_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV1595103.1"
                     /translation="MKTSLKLYFTALVASFLLLLGACSTNSSTSQTETSSSAPTEVTI
                     KSSLDEVKLSKVPEKIVTFDLGAADTIRALGFEKNIVGMPTKTVPTYLKDLVGTVKNV
                     GSMKEPDLEAIAALEPDLIIASPRTQKFVDKFKEIAPTVLFQASKDDYWTSTKANIES
                     LASAFGETGTQKAKEELAKLDKSIQEVATKNESSDKKALAILLNEGKMAAFGAKSRFS
                     FLYQTLKFKPTDTTFEDSRHGQEVSFESVKEINPDILFVINRTLAIGGDNSSNDGVLE
                     NALIAETPAAKNGKIIQLTPDLWYLSGGGLESTKLMIEDIQKALK"
     gene            complement(12563..13315)
                     /locus_tag="VYO11_000500"
     CDS             complement(12563..13315)
                     /locus_tag="VYO11_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000764290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1595104.1"
                     /translation="MKLENIDKSIQKQDILQGISLEVSPQKLTAFIGPNGAGKSTLLS
                     IMSRLTKKDQGVLSIKGREIESWNSQELAQELTILKQKINYQAKLTVEELVSFGRFPY
                     SRGRLRSEDWEKIRETLNYLELTNLKDRYINSLSGGQLQRVFIAMVLAQDTDFILLDE
                     PLNNLDIKQSVSMMQILRRLVEELGKTIIIVLHDINMASQYADEIVAFKDGQVFSKGS
                     TDQIMQADLLSQLYEIPITLADINDKKICIYS"
     gene            complement(13312..14268)
                     /locus_tag="VYO11_000501"
     CDS             complement(13312..14268)
                     /locus_tag="VYO11_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HEV1595105.1"
                     /translation="MQTKSKHTKLFWILIILAIGACLLYFWPITHLSAFAWKLRSQKI
                     IVYLLVAIATGISTISFQTLTENRFLTPSILGIESFYVLLQTLLLVFESKFLQLGKSP
                     ILEFLVLLLVQSLFFLALQGYLKTLMKQDLVFILLICLALRSLFRNISTFLQVLMDPN
                     EYDKLQNSLFASFQHLNTSILAIGSLIILALTIFFFRKAVVLDVLHLQRETAQILGLD
                     VEKEQKELLWGIVLLTSTATALVGPMAFFGFMLANLTYLIVKDYQHKLLFIVAILVGF
                     ISLTLGQALIERVFALEIRISMIIESVGGFLFFILLYRRARQ"
     gene            complement(14258..15217)
                     /locus_tag="VYO11_000502"
     CDS             complement(14258..15217)
                     /locus_tag="VYO11_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1595106.1"
                     /translation="MKLSHYLIGLLLLLVFLSISIGTSDFSWGKLFDFDQQTWLLFQE
                     SRLPRTISILLTASSMSMAGLLMQTITQNQFAAPSTVGTTEAAKLGMVLSLFVFPSAS
                     LTQKMLFAFVSSIVFTLFFLAFMTIFTVKERWMLPLIGIIYSGIIGSVTEVIAYRFNL
                     VQSMTAWTQGSFSMIQTHQYEWLFLGLIILITVWKLSQTFTIMNLGKETSESLGISYS
                     LLEKLALFLVALTTSVTMITVGGLPFLGVIVPNLVRKCYGDNLSQTKLMVALVGANLV
                     LACDILSRVLIRPYELSVSLLLGIIGSLVFILLLWRGGRKDAD"
     gene            complement(15640..16341)
                     /locus_tag="VYO11_000503"
     CDS             complement(15640..16341)
                     /locus_tag="VYO11_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase"
                     /protein_id="HEV1595107.1"
                     /translation="MTKTILVTGGTSYIGSHTVKALLNAGYKVHVLDNLSTGNRAAVD
                     SRASFKELDVYDASALKAYLKENQIDAVLHYAGEIVVSESIENPSKYFTANVAGRNQV
                     LKVLSEVGTQKIMFSSTASLYGNNCIDKPATEDTLIDPVNPYTETKLMGERMIYWMAN
                     RYDWKYVIFRYFNVAGAEMDASNGLRVKNPTHIIPNINKTALGQNDSLKIFGDDYDTR
                     DGSCIRDYIYVLDLA"
     gene            16741..17805
                     /gene="pepA"
                     /locus_tag="VYO11_000504"
     CDS             16741..17805
                     /gene="pepA"
                     /locus_tag="VYO11_000504"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HEV1595108.1"
                     /translation="MTTLFSKIKEVTELAAVSGHEAPVRAYLREKLTPHVDEVVTDGL
                     GGIFGIKHSEAVDAPRVLVASHMDEVGFMVSEIKPDGTFRVVEIGGWNPMVVSSQRFK
                     LLTRDGHEIPVISGSVPPHLTRGKGGPTMPAIADIVFDGGFADKAEAESFGIRPGDTI
                     VPDSSAILTANEKNIISKAWDNRYGVLMVSELAEALSGQKFGNELYLGSNVQEEVGLR
                     GAHTSTTKFDPEVFLAVDCSPAGDVYGGQGKIGDGTLIRFYDPGHLLLPGMKDFLLTT
                     AEEAGIKYQYYCGKGGTDAGAAHLKNGGVPSTTIGVCARYIHSHQTLYAMDDFLEAQA
                     FLQALVKKLDRSTVDLIKHY"
     gene            17827..18123
                     /locus_tag="VYO11_000505"
     CDS             17827..18123
                     /locus_tag="VYO11_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEV1595109.1"
                     /translation="MAEPNLESLIKDLYNHARHDLSEDLVAALLETTKKLPTTNEQLQ
                     AVRLSGLVNRELLLNPKHPAPELLNLARFIKREEAKYRGTATSALMYEELFKML"
     gene            18805..19248
                     /locus_tag="VYO11_000506"
     CDS             18805..19248
                     /locus_tag="VYO11_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEV1595110.1"
                     /translation="MKDSHLLAHHIRLLNGRIFQKLLSQDPEALYRGEQGKILAVLWN
                     SETGCATATDIALATGLANNTLTTMIKKLEEQKLVIVSPCGKDKRKKYLVLTELGKSQ
                     KEVGHRVSQKLDTIFYKGFSEEEIHQFEGFQERILANLKEKGNEV"
     gene            19252..20016
                     /locus_tag="VYO11_000507"
     CDS             19252..20016
                     /locus_tag="VYO11_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HEV1595111.1"
                     /translation="MSQQVKNAHNLYIHAIQDGRVAEAQAQSVGDTYIQHSTGVPDGK
                     EGFAAFFADFFERHPERQIKIVRTIEDGNLVFVHVHQYLNGGEAQWVTTDTFRADENG
                     RIVEHWDVIDYYRTPENDQLDQIFGDFEIKDLDKKAENKKLVRRFLTEIFQNGELEQW
                     SDYVADDLIQHNHEIGQGSAAYKNYVAEYSVTFDFVFQLLGQGNYVVSYGQTQIDGVA
                     YAQYDIFRLENGKIVEHWDNKEVMPKVEDLTNRGKF"
     gene            20031..20759
                     /locus_tag="VYO11_000508"
     CDS             20031..20759
                     /locus_tag="VYO11_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1595112.1"
                     /translation="MIEYKNVALRYTEKDVLRDVNLQIEDGEFMVLVGPSGSGKTTML
                     KMINRLLEPTDGNIYMDGKRIKDYDERELRLSTGYVLQAIALFPNLTVAENIALIPEM
                     KGWSKEEITKKTEELLAKVGLPVAEYGHRLPSELSGGEQQRVGIVRAMIGQPKIFLMD
                     EPFSALDAISRKQLQVLTKELHKEFGMTTIFVTHDTDEALKLADRIAVLQDGEIRQVA
                     NPETILKAPATDFVADLFGGSVHD"
     gene            20752..22272
                     /locus_tag="VYO11_000509"
     CDS             20752..22272
                     /locus_tag="VYO11_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HEV1595113.1"
                     /translation="MTNLIATFQDRFSDWLTALSQHLQLSLLTLLLAILLAIPLAVFL
                     RYHEKLADWVLQIAGIFQTIPSLALLGLFIPLMGIGTLPALTALVIYAIFPILQNTIT
                     GLKGIDPNLQEAGIAFGMTRWERLKKFEIPLAMPVIMSGIRTAAVLIIGTATLAALIG
                     AGGLDSFILLGIDRNNASLILIGALSSAVLAIAFNFLLKVMEKAKLRTIFSGFALVAL
                     LLGLSYSPALLAQKEKENLIIAGKIGPEPEILANMYKLLIEENTSMTATVKPNFGTTS
                     FLYEALKKGDIDIYPEFTGTVTESLLQPSPKVSHEPEQVYQVARDGIAKQDHLAYLKP
                     MSYQNTYAVAVPKKIAQEYGLKTISDLKKVEGQLKAGFTLEFNDREDGNKGLQSMYGL
                     NLNVATMQPALRYQAIQSGDIQITDAYSTDAELERYDLQVLEDDKQLFPPYQGAPLMK
                     EALLKKHPELETVLNKLAGKITESQMSQLNYQVGVEGKPAEQVAKEFLQEQGLLKK"
     gene            22617..23423
                     /locus_tag="VYO11_000510"
     CDS             22617..23423
                     /locus_tag="VYO11_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide riboside transporter PnuC"
                     /protein_id="HEV1595114.1"
                     /translation="MHTYLQKKIENIKTTLGEMSGGYRRMVAAMADLGFSGTMKAIWD
                     DLFAHRSFAQWIYLLVLGSFPLWLELVYEHRIVDWIGMICSLTGIICVIFVSEGRASN
                     YLFGLINSVIYLILALQKGFYGEVLTTLYFTVMQPIGLLVWIYQAQFKKEKQEFVARK
                     LDGKGWTKYLSISVLWWLAFGFIYQSIGANRPYRDSITDATNGVGQILMTAVYREQWI
                     FWAATNVFSIYLWWGESLQIQGKYLIYLINSLVGWYQWSKAAKQNTDLLN"
     gene            complement(23589..24125)
                     /locus_tag="VYO11_000511"
     CDS             complement(23589..24125)
                     /locus_tag="VYO11_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEV1595115.1"
                     /translation="MTNIDRRISKTKKAIYQAFIQLLNAKGYEATTVQDIIDLADVGR
                     STFYCHYESKELLLDQLCRYLFHHLFEREQAISTEDYLAHLFLHFHKNQDHITSLLFS
                     KNDYFLRQLHKELEHHVYSVLADNLKEAHPNLPTSYLQHLVMSNFIETLTWWLKKGQD
                     FTDQEVVQFYLDLLIPKN"
     gene            24258..25148
                     /locus_tag="VYO11_000512"
     CDS             24258..25148
                     /locus_tag="VYO11_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000645104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HEV1595116.1"
                     /translation="MKAKYAVWVAFFLNLTYAIVEFIAGGVFGSSAVLADSVHDLGDA
                     IAIGISAFLETISNREEDNQYTLGYKRFSLLGALVTAVILVTGSVLVVLENVTKILHP
                     QPVNDEGILWLGIIAITINLLASLVVGKGKTKNESILSLHFLEDTLGWVAVILMAIVL
                     RFTDWYILDPLLSLVISFFILSKALPRFWSTLKIFLDAVPEGLDIKQVKSGLERLDNV
                     ASLNQLNLWTMDALEKNAIVHVCLKEMEHMETCKESIRIFLKDCGFQNITIEIDADLE
                     THQTHKRKVCDLERSYEHQH"
     gene            25392..25745
                     /locus_tag="VYO11_000513"
     CDS             25392..25745
                     /locus_tag="VYO11_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEV1595117.1"
                     /translation="MNIKSASDLLGISADTIRYYERVGLVPPITRTATGIRDFQDQDI
                     EALEFIKCFRSAGVSVDSLVDYMSLYQKGDETREERLGILEEEKQKLEERLSQLQTAL
                     NRLNLKIKLYKEGKF"
     gene            25746..26783
                     /locus_tag="VYO11_000514"
     CDS             25746..26783
                     /locus_tag="VYO11_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HEV1595118.1"
                     /translation="MKSAVYTKAGQVGLASIERPQIIEADDVIIRVVRACVCGSDLWR
                     YRNPETKAGHKNSGHEAIGIVEEAGEAVTTVKPGDFVIVPFTHGCGECDACLAGFDGS
                     CDNHIGNNLGGDFQAEYIRFHYANWALVKIPGQPSDYTEGMLQSLLTLADVMPTGYHA
                     ARVANVQKGDKVVVIGDGAVGQCAVIAAKMRGASQIILMSRHEDRQKMAMESGATAVV
                     AERGQEGITKVREILGGGADAALECVGTEAAIEQALGVLHNGGRMGFVGVPHYNNRAL
                     GSTFMQNISVAGGAASATTYDKQFLLKAVLDGDINPGRVFTSSYKLEDIDQAYKDMDE
                     RKTIKSMIVIE"
     gene            complement(26829..27836)
                     /gene="galR"
                     /locus_tag="VYO11_000515"
     CDS             complement(26829..27836)
                     /gene="galR"
                     /locus_tag="VYO11_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000212522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator GalR"
                     /protein_id="HEV1595119.1"
                     /translation="MATLKDIAQLASVSIATVSRVLNRDQSLSVTEETRHRILTVAEE
                     LGYTKHLKTGESHKPKQKIAIIQWVSEQGELDDLYYYQIRLGIEKRAQELDYDILRYF
                     NDHPFTLSEEVIGILCIGKFSRAQISAFEEYQKPLVFLDSDTLSLGHTCIITDFYTAM
                     KQVVDYFLSQGMDRIGILTGLEETTDQEEIIQDKRLENFKNYSQARGIYHDELVFQGR
                     FTAQSGYDLMKEAIQSLGDQLPPAFFAASDSLAIGALRALQEAGISLPDRVSLISFND
                     TSLTKQVYPPLSSITVYTEEMGRAGMDILNKEVLHGRKIPSLTMLGTRLTLRESTLNQ
                     E"
     gene            28001..29179
                     /locus_tag="VYO11_000516"
     CDS             28001..29179
                     /locus_tag="VYO11_000516"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HEV1595120.1"
                     /translation="MAQHLTTEVLRKDFLAVFGQEADQTFFSPGRINLIGEHTDYNGG
                     HVFPAAISLGTYGAARKRDDQVLRFYSANFEDKGIIEVPLADLKFEKEHNWTNYPKGV
                     LHFLQEAGHVIDKGFDFYVYGNIPNGAGLSSSASLELLTGVVAEHLFDLKLERLDLVK
                     IGKQTENNFIGVNSGIMDQFAIGMGADQRAIYLDTNTLEYDLVPLDLKDNVVVIMNTN
                     KRRELADSKYNERRAECEKAVEELQVALDIQTLGELDEWAVDQYSYLIKDENRLKRAR
                     HAVLENQRTLKAQAALQAGDLETFGRLMNASHVSLEHDYEVTGLELDTLVHTAWAQEG
                     VLGARMTGAGFGGCAIALVQKDTVEAFKEAVGKHYEEVVGYAPSFYIAEVAGGTRVLD
                     "
     gene            29198..30679
                     /locus_tag="VYO11_000517"
     CDS             29198..30679
                     /locus_tag="VYO11_000517"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HEV1595121.1"
                     /translation="MILVDKFVTHVISESSFEEMDRIYLTNRVLARVGEGVLEVETNL
                     DKLIDLKDQLVEEAVRLETIEDSQTAREILGTELMDLVTPCPSQVNRDFWEAYAYSPE
                     QAIEDFYQLSQKNDYIKLKAIAKNIAYRVPSDYGELEITINLSKPEKDPKEIAAAKLV
                     QASNYPQCQLCLENEGYHGRVNHPARTNHRIIRFEMVGQEWGFQYSPYAYFNEHCIFL
                     DGQHRPMAISRQSFERLLAIVEQFPGYFAGSNADLPIVGGSILTHDHYQGGRHVFPME
                     LAPLQKTFRFAGFEQVKAGIIKWPMSVLRLTSDSKEDLINLADKIFQEWRQYSDSSVQ
                     ILAETDGTPHHTITPIARKRDGQFELDLVLRDNQTSAEHPDGIYHPHKDVQHIKKENI
                     GLIEVMGLAILPPRLKEEVEQVASYLVGEAVTVADYHQEWADQLKSQHPDLTDKEKAL
                     AIVKDSVGAIFVRVLEDAGVYKQTEQGQAAFMRFVEQVGISLD"
     gene            30749..31153
                     /locus_tag="VYO11_000518"
     CDS             30749..31153
                     /locus_tag="VYO11_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HEV1595122.1"
                     /translation="MKDFHFDAISAFENYEIEKMRDGHVVVTTKVVNSSLNYYGNAHG
                     GYLFTLCDQISGLVVISLGLDGVTLQSSINYLKAGKLDDVLTIKGECVHQGRTTCVMD
                     VDITNQEGRNVCKATFTMFVTGRRSEDRQVRI"
     gene            31310..32164
                     /locus_tag="VYO11_000519"
     CDS             31310..32164
                     /locus_tag="VYO11_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012972462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA adenine methylase"
                     /protein_id="HEV1595123.1"
                     /translation="MKIKEIKKVTLQPFTKWTGGKRQLLPVIRELIPKTYNRYFEPFV
                     GGGALFFDLAPKDAVINDFNAELINCYQQIKDNPQELIEILKVHQEYNSKEYYLDLRS
                     ADRDERIDMMSEVQRAARILYMLRVNFNGLYRVNSKNQFNVPYGRYKNPKIVDEELIS
                     AISVYINNNQLEIKVGDFEKAIVDVRTGDFVYFDPPYIPLSETSAFTSYTHEGFSFAD
                     QVRLRDAFKRLSDTGAYVMLSNSSSALVEELYKDFNIHYVEATRTNGAKSSSRGKISE
                     IIVTNYEK"
     gene            32190..32960
                     /locus_tag="VYO11_000520"
     CDS             32190..32960
                     /locus_tag="VYO11_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HEV1595124.1"
                     /translation="MTKPYYNKNKMILVHSDTFKFLSKMKPESMDMIFADPPYFLSNG
                     GISNSGGQVVSVDKGDWDKISSFEEKHEFNRKWIRLAKEVLKPNGTVWISGSLHNIYS
                     VGMALEQEGFKILNNITWQKTNPAPNLSCRYFTHSTETILWARKNDKKARHYYNYDLM
                     KELNDGKQMKDVWTGSLTKKVEKWAGKHPTQKPEYLLERIILASTKEGDYILDPFVGS
                     GTTGVVAKRLGRRFIGIDAEKEYLKIARKRLEAENETN"
     gene            32947..33813
                     /locus_tag="VYO11_000521"
     CDS             32947..33813
                     /locus_tag="VYO11_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000815109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type-2 restriction enzyme DpnII"
                     /protein_id="HEV1595125.1"
                     /translation="MKQTRNFDEWLSTMTDTVADWTYYTDFPKVYKNVSSIKVALNIM
                     NSLIGSKNIQEDFLDLYQNYPEILKVVPLLIAKRLRDTIIVKDPIKDFYFDFSKRNYS
                     IEEYTMFLEKSGIFDLLQNHLVSNLVDYVTGVEVGMDTNGRKNRTGDAMENIVQSYLE
                     AEGYILGENLFKEIEQNEIEEIFSVDLSAITNDGNTVKRFDFVIKNEQVLYLIEVNFY
                     SGSGSKLNETARSYKMIAEETKAIPNVEFMWITDGQGWYKAKNNLRETFDILPFLYNI
                     NDLEHNILKNLK"
     gene            complement(33900..35162)
                     /locus_tag="VYO11_000522"
     CDS             complement(33900..35162)
                     /locus_tag="VYO11_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001194492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HEV1595126.1"
                     /translation="MQTQEKHSQAAVLGLQHLLAMYSGSILVPIMIATALGYSAEQLT
                     YLISTDIFMCGVATFLQLQLNKYFGIGLPVVLGVAFQSVAPLIMIGQSHGSGAMFGAL
                     IASGIYVVLVSGIFSKVANLFPSIVTGSVITTIGLTLIPVAIGNMGNNVPEPTGQSLL
                     LAAITVLIILLINIFTKGFIKSISILIGLVVGTAIAATMGLVDFSPVAVAPLVHVPTP
                     LYFGMPTFEISSIAMMCIIATVSMVESTGVYLALSDITKDPIDSTRLRNGYRAEGLAV
                     LLGGIFNTFPYTGFSQNVGLVKLSGIKKRLPIYYAAGFLVLLGLLPKFGALAQIIPSS
                     VLGGAMLVMFGFVSIQGMQILARVDFANNEHNFLIAAVSIAAGVGLNNSNLFVSMPTA
                     FQMFFSNGIVVASLLAIVLNAVLNHKKK"
     gene            complement(35162..35743)
                     /locus_tag="VYO11_000523"
     CDS             complement(35162..35743)
                     /locus_tag="VYO11_000523"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000770427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HEV1595127.1"
                     /translation="MKLLEERILKDGHILGDNILKVDSFLTHQVDFSLMREIGKVFAE
                     KFAATGITKVVTIEASGIAPAVFTAEALNVPMIFAKKAKNITMNEGILTAQVYSFTKQ
                     VTSTVSIAGKFLSPEDKVLIIDDFLANGQAAKGLIQIIEQAGATVQAIGIVIEKSFQD
                     GRDLLEKAGYPVLSLARLDRFENGQVVFKEADL"
     regulatory      complement(36143..36238)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            complement(36622..36861)
                     /locus_tag="VYO11_000524"
     CDS             complement(36622..36861)
                     /locus_tag="VYO11_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HEV1595128.1"
                     /translation="MLEEGTKDQLAELTYLFGRGVNLSFGIKDVSKLYQRVMKANYPI
                     YRPLTKRKFRVSDHYIYPHEFAVLDPDSYFLRFSE"
     gene            complement(36861..37004)
                     /locus_tag="VYO11_000525"
     CDS             complement(36861..37004)
                     /locus_tag="VYO11_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HEV1595129.1"
                     /translation="MDYNAVIPELLVSNIEQSRSFYCDLLGFRIEYQRPEENFLFLLK
                     SVN"
     gene            complement(37016..37843)
                     /gene="xth"
                     /locus_tag="VYO11_000526"
     CDS             complement(37016..37843)
                     /gene="xth"
                     /locus_tag="VYO11_000526"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006596696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HEV1595130.1"
                     /translation="MKLISWNIDSLNAALTSDSARAKLSQEVLQTLVAENADIIAIQE
                     TKLSAKGPTKKHVEILEELFPGYENTWRSSQEPARKGYAGTMFLYKKELTPTVTFPEI
                     GAPSTMDLEGRIITLEFDAFFVTQVYTPNAGDGLKRLEERQVWDVKYAEYLAELDKEK
                     PVLATGDYNVAHNEIDLANPASNRRSPGFTDEERAGFTNLLATGFTDTFRHVHGDVPE
                     RYTWWAQRSKTSKINNTGWRIDYWLTSNRIADKVTKSDMIDSGARQDHTPIVLEIDL"
     gene            37976..38431
                     /locus_tag="VYO11_000527"
                     /pseudo
     CDS             37976..38431
                     /locus_tag="VYO11_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730499.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3290 family protein"
     gene            38584..38880
                     /locus_tag="VYO11_000528"
     CDS             38584..38880
                     /locus_tag="VYO11_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001276342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HEV1595131.1"
                     /translation="MSASDVALKLRGQGIFQMKQVKRAVQEQNGQLIVVQMGDENSKY
                     PVVTDGVIQVDVLESIGRSEEWLLDNLSKQGHDNVANIFIAEYDKGAVTVVTYE"
     gene            39086..40831
                     /locus_tag="VYO11_000529"
     CDS             39086..40831
                     /locus_tag="VYO11_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV1595132.1"
                     /translation="MSIIQKLWWFFKLEKRRYLVGIVALVLVSVLNLIPPMVMGRVID
                     AITSGQLTQQDLLLSLFYLLLAAFGMYYLRYVWRMYILGTSYCLGQIMRSRLFKHFTK
                     MSSAFYQTYRTGDLMAHATNDINALTRLAGGGVMSAVDASITALVTLLTMLFSISWQM
                     TLVAILPLPFMAYATSRLGRKTHKAFGESQAAFSELNNKVQESVSGIKVTKSFGYQAD
                     ELKSFQAVNELTFQKNLQTMKYDSLFDPMVLVFVGSSYVLTLLVGSLMVQEGQITVGN
                     LVTFISYLDMLVWPLMAIGFLFNTTQRGKVSYQRIENLLSQESPVQDPEFPLDGIENG
                     CLEYAIDSFAFENEETLTDIHFSLAKGQTLGLVGQTGSGKTSLIKLLLREYDVDKGAI
                     YLNGHDIRDYRLTDLRSLMGYVPQDQFLFATSILDNIRFGNPNLPLSAVEEATKLARV
                     YQDIVDMPQGFDTLIGEKGVSLSGGQKQRLAMSRAMILDPDILILDDSLSAVDAKTEY
                     AIIDNLKETRKDKTTIITAHRLSAVVHADFILVLQNGQIIERGRHEDLLAMDGWYAQT
                     YQSQQLEMKGEEDAE"
     gene            40821..42572
                     /locus_tag="VYO11_000530"
     CDS             40821..42572
                     /locus_tag="VYO11_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1595133.1"
                     /translation="MQNKQEQWAVLKRLMSYLKPYRLLTFLALSFLLATTVIKSVIPL
                     VASHFIDQYLSNLNQLAVTVLLVYYGLYILQTVVQYVGNLLFARVSYSIVRDIRRDAF
                     ANMEKLGMSYFDKTPAGSIVSRLTNDTETISDMFSGILSSFISAVFIFLTTLYTMLVL
                     DFRLTALVLLFLPLIFLLVNLYRKKSVKIIEKTRSLLSDINSKLAENIEGIRIIQAFN
                     QEKRLQAEFDEINQEHLVYANRSVALDALFLRPAMSLLKLLGYAVLMAYFGYRGFSIG
                     ITVGTMYAFIQYINRLFDPLIEVTQNFSTLQTAMVSAGRVFALIDERTYEPLQENGQA
                     KVQEGNIRFEHVCFSYDGKHPILDDISFSVNKGETIAFVGHTGSGKSSIINVLMRFYE
                     FQSGRVLLDDVDIRDFSQEELRKNIGLVLQEPFLYHGTIKSNIAMYQETSDEQVQAAA
                     AFVDADSFIQELPQGYDSPVSERGLSFSTGQRQLLAFARTVASQPKILILDEATANID
                     SETESLVQASLAKMRQGRTTIAIAHRLSTIQDANCIYVLDKGRIIESGTHEELLALGG
                     TYHKMYSLQAGAMADTL"
     gene            42745..43437
                     /locus_tag="VYO11_000531"
     CDS             42745..43437
                     /locus_tag="VYO11_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000922225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HEV1595134.1"
                     /translation="MLKWEDLPVEMKSSEVESYYQLVSKRKGSLIFKRCLDWVLALVL
                     LVLTSPIFLILSIWIKLDSKGPVIYKQERVTQYNCRFKIWKFRTMVTDADKKGSLVTS
                     ANDSRITKVGNFIRRVRLDELPQLVNVLKGEMSFVGTRPEVPRYTEQYSPEMMATLLL
                     QAGITSPASINYKDEDTIISQMTEKGLSVDQAYVEHVLPEKMRYNLAYLREFSFFGDI
                     KIMFQTVFEVLK"
     gene            43480..44706
                     /locus_tag="VYO11_000532"
     CDS             43480..44706
                     /locus_tag="VYO11_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001134527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegT/DnrJ/EryC1/StrS aminotransferase family
                     protein"
                     /protein_id="HEV1595135.1"
                     /translation="MPNYNIPFSPPDITEAEIAEVADTLRSGWITTGPKTKELERRLS
                     LYTQTPKTVCLNSATAALELILRVLEVGPGDEVIVPAMTYTASCSVITHVGATPVMVD
                     IQADTFEMDYDLLEQAITEKTKVIIPVELAGIVCDYDRLFQVVEKKRDFFTASSKWQK
                     AFNRIVIVSDSAHALGSTYKGQPSGSIADFTSFSFHAVKNFTTAEGGSATWKANPVID
                     DEEMYKEFQILSLHGQTKDALAKMQLGSWEYDIVTPAYKCNMTDIMASLGLVQLDRYP
                     SLLQRRKDIVDRYDSGFAGSRIHPLAHKTETVESSRHLYITRVEGASLEERNLIIQEL
                     AKAGIASNVHYKPLPLLTAYKNLGFDMTNYPKAYAFFENEITLPLHTKLSDEEVDYII
                     ETFKTVSEKVLTLSKK"
     gene            45836..47995
                     /gene="pfbA"
                     /locus_tag="VYO11_000533"
     CDS             45836..47995
                     /gene="pfbA"
                     /locus_tag="VYO11_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multi-ligand-binding adhesin PfbA"
                     /protein_id="HEV1595136.1"
                     /translation="MLKIVKKLEVLMKYFVPNEVFSIRKLKVGTCSVLLAISILGSQG
                     ILSDEVVTSSSPMATKESSNAITNDLDNSPTVNQNRSAEMIASNSTTNGLDNSLSVNS
                     ISSNGTIRSNSQLDNRTVESTVTSTNENKSYKEDVISDRIIKKEFEDTALSVKDYGAV
                     GDGIHDDRQAIQDAIDAAAQGLGGGNVYFPEGTYLVKEIVFLKSHTHLELNEKATILN
                     GINIKNHPSIVFMTGLFTDDGAQVEWGPTEDISYSGGTIDMNGALNEEGTKAKNLPLI
                     NSSGAFAIGNSNNVTIKNVTFKDSYQGHAIQIAGSKNVLVDNSRFLGQALPKTMKDGQ
                     IISKESIQIEPLTRKGFPYALNDDGKKSENVTIQNSYFGKSDKSGELVTAIGTHYQTL
                     STQNPSNIKILNNHFDNMMYAGVRFTGFTDVLIKGNRFDKKVKGESVHYRESGAALVN
                     AYSYKNTKDLLDLNKQVVIAENIFNIADPKTKAIRVAKDSAEYLGKVSDITVTKNVIN
                     NNSKETEQPNIELLRVSDNLVVSENSIFGGKEGIVIEDSKGKITVLNNQFYNLSGKYI
                     SFIKSNANGKEPVIRDSDGNFNIVTENGLYNIVTNNLSDKNEKEKNKEEKQSNSNNVI
                     DSNQKNGEFNSSKDNRQMNDKIDNKQDNKTEEVNYKIVGDGRETENHINKSKEIVDVK
                     QKLPKTGSNKIMELFLTVTGIGLLLTLKGLKYYGKDK"
     gene            47979..48275
                     /locus_tag="VYO11_000534"
     CDS             47979..48275
                     /locus_tag="VYO11_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1595137.1"
                     /translation="MVKINKICSIQGSSVENEDIVGSQNQYFWIIGGATDLYNSKEEI
                     GYSVSEVVHILSESLSVNCKESKTLKQIFETALLEVKDEIGLNSYELTEYSKMK"
     gene            48517..48825
                     /locus_tag="VYO11_000535"
                     /pseudo
     CDS             48517..48825
                     /locus_tag="VYO11_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000996568.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GDP-mannose 4,6-dehydratase"
     gene            48989..49648
                     /locus_tag="VYO11_000536"
     CDS             48989..49648
                     /locus_tag="VYO11_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000793810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1868 domain-containing protein"
                     /protein_id="HEV1595138.1"
                     /translation="MKNLTKIKFKENGEFNHFPGNTVVANLYTKQDLMEVVDIIQSRY
                     RELPFIDKFTLTPRNSIHMTVIELLCHENRETEFWSSNLPLDTPLQEIHDYFAKQLEI
                     FPLLDEEIHMRITEMGKQNILVEPADEASAKRLEEIRTYVSEKAGVCFPNHDRYQFHI
                     SIGYLRIPLTEEEEEEFTKVRAELTEILLEKIPTITVNRIDYTVFEDMRQFVPYHEKF
                     K"
     gene            49673..50740
                     /locus_tag="VYO11_000537"
     CDS             49673..50740
                     /locus_tag="VYO11_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEV1595139.1"
                     /translation="MKKMKVWSTVLATGVALTTLAACSGGSNSTTASSSEEKADKSQE
                     LVIYSNSVSNGRGDWLTAKAKEAGFNIKMVDIAGAQLADRVIAEKNNAVADMVFGIGA
                     VDSNKIRDQKLLVQYKPKWLDKIDQSLSDKDNYYNPVIVQPLVLIGAPDVKEMPKDWT
                     ELGSKYKGKYSIYGLQGGTGRAILASILVRYLDEKGDLGVSEKGWEVAKEYFANAYTL
                     QKGESSVVKALDKESPIQYGMIWGSGSLIGQKEQNVEFKVMTPEIGVPFVTEQTMVLS
                     TSKKQALAKEFIDWFGQSEIQVEYSKKFGSIPANKDALKELPEDTKKFVDQVKPQNID
                     WEAVGKHLDEWVEKAELEYVQ"
     gene            50843..51853
                     /locus_tag="VYO11_000538"
     CDS             50843..51853
                     /locus_tag="VYO11_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1595140.1"
                     /translation="MIKFDNIQIKYGDFVAIDNLNLDIHEGEFFTFLGPSGCGKSTTL
                     RALVGFLDPSSGSIEVNGTDVTHLEPEKRGIGIVFQSYALFPTMTVFDNIAFGLKVKK
                     VAPDVIKAKVSAVAAKIKISDQQLQRNVSELSGGQQQRVALARALVLEPKILCLDEPL
                     SNLDAKLRVDLRKELKRLQKELGITTLYVTHDQEEALTLSDRIAVFNNGYIEQVGTPV
                     EIYHNSQTEFVCDFIGDINVLTDETVHEVLLKNTSVFLEDKKGYIRLEKVRFNRETEQ
                     DFILKGTIIDVEFSGVTIHYTIKVSESQILNVTSIDSQAAIRSVGESVELFITPSDVL
                     QF"
     gene            51865..53556
                     /locus_tag="VYO11_000539"
     CDS             51865..53556
                     /locus_tag="VYO11_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEV1595141.1"
                     /translation="MRHKLNLKDWLIRLGLIWFLVTFIIYPNFDLVVNVFVKGGEFSL
                     DAVHRVLKSQRALQSIMNSFKLAFSLIITVNVVGILCVLFTEYFDIKGAKILKLGYMT
                     SLIYGGVVLATGYKFVYGPYGLITKFLQNVIPSLDSNWFIGYGAVLFIMTFSGTANHT
                     LFLTNTIRSVDYHTIEAARNMGAKPFTVFRKVVLPTLIPTLFALTIMVFLSGLSAVAA
                     PMIVGGKEFQTINPMIITFAGMGNSRDLAALLAIILGIATTILLTIMNKIEKGGNYIS
                     ISKTKAPLKKQKIASKPWNIIAHIVAYGLFTVFMLPLIFIVLYSFTDPVAIQTGNLTL
                     SNFTLENYRLFFSNSAAFSPFLVSFIYSIIAATTATILAVVFARVVRKHKSRFDFLFE
                     YGALLPWLLPSTLLAVSLLFTFNQPQFLVLNQILVGSLVILLIAYIVVKIPFSYRMVR
                     AILFSVDDEMEDAARSMGASPFYTMMKVIIPFILPVVLSVIALNFNSLLTDFDLSVFL
                     YHPLAQPLGITIRSAGDETATSNAQALVFVYTIVLMIISGTVLYFTQRPGRKVRK"
     gene            53559..54269
                     /locus_tag="VYO11_000540"
     CDS             53559..54269
                     /locus_tag="VYO11_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000127555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HEV1595142.1"
                     /translation="MTATSLGLSNIEIVVRIVLSVVIGSIIGLERGSKSQPAGIRTYS
                     IVCLAACLIMMTNEYVSYKFGTGDPTRLGAQVISGVGFLGAGTILITDKKKITGLTTA
                     AGIWASAGIGLAIGVGFYEGALLVAISVWGVISMFQPLKKYLQNRSKMIELYIVVKST
                     EAYNRVLVYCAENGIRMTDSRTAFGDVNSDRIEYFDVPDKKIASFITLELSGRFEHLR
                     LMEEIANIVGVIYVEEIS"
BASE COUNT        16237 a         9782 c        12108 g        16278 t
ORIGIN      
        1 agtaattttg tgataaaatg taattgttcc atatgattct ttctaatgag ttgttttgtc
       61 gcttttcatt ataggtcata tgggactttt tttctacaca aaataggctc cataatatcc
      121 atagggggtt acccactaca aatattatag agccgaaaaa ggctgagatc tggtgtctca
      181 gtcttttatt tcttgcgttt tgcaaaatct acaaatctaa atttttctaa cttatggcga
      241 ctttcggtaa actgaaattg gcgtccgtct tggagataga cttttgattt aatcgaaacg
      301 acataagggt ctttgccaat gtccatgaga atcttgtctc ggtcgcttga gtggtcaatg
      361 gtgatttcct tctgagcata atcaataagg agtttgaggc cattttctat ataagaatag
      421 atagactgct cagcaatttg gcgagtgaga tttggaatta gttccatatc cagatagtct
      481 gtatccagaa cggataccag atcatccacc acacgctggc ggaccacctt ccaaaccatc
      541 cgaaactctg ggaaaccggt tatcagtgag gattttttat caataataat cttgtccaga
      601 ctgaccacgt tggttttaga gcgcagtcca agttctttaa ctagttcttg gtagctggtt
      661 aggttggata cagggaaatt gacggtttct tctttgacga cttgagaacc ttgccctctt
      721 atctttttga tcaatccttc ctcttggagg agagacaggg cctttcggac ggtatcacga
      781 ctcacttgat attgctccat aaggtcgtgc tcgctaggaa ggaaatctcc gacagcgtaa
      841 gtctcgtttt gaatggtttc ttggatttgc ttaaataatt gttggtattt cttcattttg
      901 cctgcttaaa taggttttta gtctagttta atgaacacct gtatctattt taccatacaa
      961 gtgctagaaa atttacaaaa aaacaccctt tttataccaa acaagttgca gacaagtttg
     1021 gtatcgttta caatatactt atcaaatcaa acttgctttg acaagtataa ggagaatcaa
     1081 atgggaaaat ttgaacaaga agccaaagat ctgcttcagg caattggagg caaagaaaat
     1141 gtgactgccg tcacccactg tgcgacacgg atgcgctttg ttttaggaga tgataagaag
     1201 gctaatgtta aagctatcga gtcaattcca gctgttaaag gaacttttac aaatgcaggt
     1261 caatttcagg taatcattgg aaatgacgtg cccatctttt ataatgattt tacagccgtt
     1321 tcaggtattg agggtgtttc caaagaagca gccaagtctg cagctaagag taatcaaaac
     1381 gtggtccaac gtgttatgac cactctggcg gagattttta ctccgattat tccagccttg
     1441 atagtcggag gattgatcct cggtttccgt aatgtcttgg aaggtgtcca ttggtcgatg
     1501 ttggatggca agaccatcac agaatcctct cagttttggg caggtgtcaa tcacttcctc
     1561 tggttgcctg gtgaagctat cttccagttc ttaccagtag ggattacttg gtctgtttct
     1621 cgtaagatgg gaaccagcca aattttggga attgttctcg gaatctgttt ggtatcgcct
     1681 cagttgctca atgcctatgc ggttgcttca acgccagcag ctgatatcgc ggcaaactgg
     1741 gtttggaatt ttggctattt tactgttaat cgtatcggtt accaagccca agttatccca
     1801 gccttgcttg caggtttgag tctgtcttat cttgaaatct tctggcgcaa gcatatccca
     1861 gaagtcattt ctatgatttt tgtacctttc ttgtcattga ttccagcctt gattttggct
     1921 catactgttt tgggaccaat cggttggaca attggacaag gactttcatc agttgtcttg
     1981 gcaggtttaa ctggtccagt taaatggctc ttcggtgcaa tttttggtgc cctctacgct
     2041 ccatttgtca tcacaggtct gcaccatatg accaatgcca ttgatacaca attgattgcg
     2101 gatgctggtg gcactgccct atggccaatg attgctcttt ctaatattgc tcaaggctca
     2161 gccgtgtttg tctattattt catgcatcgc catgatgagc gtgaggctca ggtttcactt
     2221 cctgcaacca tttcagccta tctcggtgtt acagaaccag ctctttttgg ggttaacgta
     2281 aaatatattt atccatttgt tgctgggatg actggttcag cccttgcagg catgttatcc
     2341 gttactttta atgtaactgc ggcttctatt ggtatcggtg gtttgccagg tattctctct
     2401 attcaacctc aatacatgct gccatttgca ggaactatgc tagttgcgat tgttgttcca
     2461 atgctcttga ctttcttctt ccgcaaggct ggtctcttta caaaaacaga gggcgatacg
     2521 aacttgcagg cagaattcgt tgctcaagaa gaagcagaat ttgtgaacca tgaaccagta
     2581 gaacttactt cggtagaaat tatcagccca ctaactggcc aagtgaaaga attgagtcaa
     2641 gcgacggatc ctatttttgc atcaggtgtc atggggcaag gtctagtcat tgaaccaagc
     2701 caaggtgagt tgacctctcc agttaatggg acagtgacgg ttcttttccc taccaagcat
     2761 gccatcggca ttgtctctga cgagggagtt gaattgctca tccacatcgg tatggataca
     2821 gtaggtcttg atggcaaagg ttttgaaagt cttgtagtcc aaggagatca cgttacagtt
     2881 ggtcagcaac tgattcgttt tgatatggat gtcattaagg ctgcaggtct ggtgacagaa
     2941 actcctgtta tcatcaccaa ccaagatgct tatacagcga ctattcccgg aacttatccg
     3001 acaacgatcc aagctggagc atctctcatg gtcgctacac gaatctaata ctcttcgaaa
     3061 atctcttcaa accacgtcag ctctatctgc aacctcaaaa tagtgttttg agcaacctgt
     3121 ggctagcttc ctagtttgtt ctttgatttt cattgagtat aattgaaata gcacaaatag
     3181 ggacggaaga ctgcttcctc ccttttatca gaaaaggaga aacagatgac acttgataaa
     3241 ggaaaagtag tctatcaaat ctatccaaaa tcttacaaag acaccactga aaacggtatt
     3301 ggggatttcc gtgggattat cgaaaaaatt ccctatttag ccaaactagg tgtggatatg
     3361 gtctggctca atccattcta tccaagccct caacgggata atggttacga tatttcagat
     3421 tatatggcag tggatcctct ttttggtgat atggctgatt ttgaggaaat ggtgtgtgtc
     3481 ggtaaagagc acaagattga ctttatgctg gacatggtac ttaatcattg ttcgacagag
     3541 catgaatggt ttcagaaagc cctagctggt gataagtatt atcaagactt tttcttcatc
     3601 caagaccaac caacagattg gcagtctaag tttggtggtt ctgcatggac gcctttcggg
     3661 gatactggga aatactatct tcacctattt gatgagaccc aggctgacct taactggcgc
     3721 aattccaatg tccgtaagga gcttttcaag gttgttaatt tctggcgcga caagggtatc
     3781 aaaggtttcc gatttgatgt gatcaatttg atcggtaagg acgaggtttc agtggactgt
     3841 cctgaaaatg aagggaagcc agcttataca gacaaaccca tcgttcataa ctatttgcgt
     3901 atgatgaacc aagccacttt tggatctgac gatagcttta tgacagttgg ggaaatgtct
     3961 tctaccacca tggaaaactg tgtcctctat tcgtcgcctg atcgtcagga attatccatg
     4021 acctttaatt ttcatcacct caaggtggac tataaggatg gacaaaagtg gaccttggct
     4081 ccctttgatt ttgaagagtt gaagagtctt taccatagtt ggggtaagga aatgagtgat
     4141 aaagacggtt ggagtgccct cttttggaac aatcacgatc aaccacgtgc cttgaaccgt
     4201 tttgtcgata ttcaaaactt ccgcaaggaa ggagccacca tgctagcggc tagcattcac
     4261 ctgtcacgtg ggacacctta tatctatatg ggtgaagaaa tcgggatgat tgacccagac
     4321 tatgattcta tggctgatta tgtggatgtc gaatcgctta atgcctatca gacgctctta
     4381 gaagaaggaa agagtcagca agaagccttc cagattattc aagctaagtc gcgtgataat
     4441 tcacgcattc ccatgcagtg ggatgcttcg gaaaatgcag gattttcaac aggcactcca
     4501 tggttgaaag ctggtaaatc ctataaatac atcaatgtag aaaatgaaat ccagggtccg
     4561 attttcacct tctatcaaga cttgattcga ctgcgtaagg aaatgccaat catttcagaa
     4621 ggaagttaca aaccagcctt tgaagatagc aaacaagtct acgcttttga acgccagttt
     4681 gaggatcaaa agttactagt gctcaataac ttttatgcta aagaagtgga aatcgacttg
     4741 ccagcagtct accaaaatgg acagattttg atatcaaact atgaagatgc agaagtgtct
     4801 gagaaaattc tactcaaacc ctatcaaaca ctggctattt atgtaaatta atactcttcg
     4861 aaaatctctt caaaccgtgt cagttttatc tgcaacctca aagcggtgct ttgagcaacc
     4921 tgtggctagc ttcctagttt gctctttgat tttcattgag tataaactta gcaaggagac
     4981 ctctttttca gaaaagcagg gttctttttg ctgtctattc catccctgaa agtgtagaac
     5041 aaactggtca gggtggctag tttgtggtat aatgaaaggg attcaaaaag aaacaggaga
     5101 aaaatgatgg atttactttt agcaattgta ttgattgtgc tagcttttct aggaggagct
     5161 cttggaggaa tgtacttggt tcgtaagcaa atcgaaaaag aatttgctga caacccacgt
     5221 ttgaatgctg aagcagttcg tactcttttg agtgcaaatg gtcaaaaacc aagcgaagct
     5281 aaggtacaac aagtttacca ccaaatcatc cgccaacaaa aggcagccct tgctaacaat
     5341 aaaaagaaaa aataaataag gaaaagtctg ggatgaaagt tccagacttc tcactatgtt
     5401 ggttatggtt tagggatgag actttttcct tgcattctat tgatatttga ttatgattaa
     5461 gagagaggta gttgacattc tatcaagctg tcggtcagtt cgttcagtac aaggaatcat
     5521 aatgaacgat caatcagaaa aaagactaga aagaagactg tatggataat cgaccaattg
     5581 gttttttgga ttcgggtgtc gggggcttga ccgttgtgcg cgagctcatg cgccagcttc
     5641 cccatgaaga aatcgtctat attggagatt cggcgcgggc gccctatggc ccccgtcctg
     5701 ctgagcaaat tcgtgaatat acttggcagc tggtcaactt tctcttgacc aaggatgtca
     5761 aaatgattgt cattgcttgt aacactgcga ctgcggtcgt ctgggaagaa atcaaggctc
     5821 aactagatat tcctgtcttg ggtgtaattt tgccaggagc ttcggcagcc atcaagtcca
     5881 gtcaaggtgg gaaaatcgga gtgattggaa cgcccatgac ggtacaatca gacatatacc
     5941 gtcagaaaat ccatgatctg gatcccgact tacaggtgga gagcttggcc tgtcccaagt
     6001 ttgctccctt ggttgagtca ggtgccctgt caaccagtgt taccaagaag gtggtctatg
     6061 aaaccctgcg tcccttggtt ggaaaggtgg atagcctgat tttgggctgt actcattatc
     6121 cactccttcg ccctattatc caaaatgtga tggggccaaa ggttcagctc atcgatagtg
     6181 gggcagagtg cgtacgggat atctcagtct tactcaatta ttttgaaatc aatcgtggtc
     6241 gcgatgctgg accactccat caccgttttt acacaacagc cagtagccaa agttttgcac
     6301 aaattggtga agaatggctg gaaaaagaga ttcatgtgga gcatgtagaa ttatgacaaa
     6361 taaaatttat gaatataagg atgaccagga ctggtatgtt gggtcttata gtatttttgg
     6421 tggcgttaac agtttgagcg actatcagac agattttcct ctgtttgaat tctccaaaat
     6481 atttggagat gaagagtatg gtttcccgct ttcagttact gttttacgct atggttctac
     6541 ctaccgtttg ttctcctttg tggtagatat gcttaatcaa gaaatgggac gaaacttgga
     6601 agttattcaa cgtcatgggg ccctgctctt ggttgaaaat gggcaactct tgtatgtaga
     6661 attgcctaaa gaaggggtca atgttcatga tttctttgag acaagcaaag tcagagaaac
     6721 cttgttgatt gcgactcgta acgaaggtaa aaccaaggaa ttccgagcta tctttgataa
     6781 gttaggctac gatgtggaaa atcttaatga ctaccctgac ctgcctgaag tagcagaaac
     6841 aggtatgacc tttgaggaaa atgcccgcct taaggcagaa accatttctc aattaacggg
     6901 caagatggtt ttggcagatg attctggtct caaagtcgat gtccttggtg gcttaccagg
     6961 cgtctggtca gctcgtttcg caggtgtggg agcaactgac cgtgaaaata atgccaaact
     7021 cttgcacgaa ttggccatgg tctttgaact caaggaccgc tcggctcagt tccacacaac
     7081 cctagtcgta gccagcccaa ataaggaaag tttagttgtt gaagcagact ggtcaggtta
     7141 tattaacttt gaacctaagg gtgaaaatgg ctttggctat gatcccctct tccttgtagg
     7201 agagacaggt gagtcatcag ctgaattaac cctggaagaa aaaaatagtc aatctcaccg
     7261 tgccttagcc gttaagaaac ttttggaggt atttccatca tggcaaagca aaccatcatt
     7321 gtaatgagcg attcccatgg cgatagcttg attgtggaag aagtccgtga tcgttatgtg
     7381 ggcaaagtcg atgccgtttt tcataacggc gattctgaac tacgtccgga ttctccactt
     7441 tgggagggca tccgcgttgt taaagggaac atggacttct acgccggcta cccagaacgt
     7501 ctggtgactg agcttggttc gaccaagatt atccaaactc atggtcactt gtttgacatc
     7561 aatttcaact ttcaaaagtt ggactactgg gctcaggagg aagaggccgc tatctgcctc
     7621 tatggtcact tgcatgtgcc aagtgcttgg ttggaaggca agatcctctt tctaaatcca
     7681 ggctctatca gtcaaccacg aggtaccatc agagaatgtc tctatgctcg tgtggagatt
     7741 gatgatagtt acttcaaagt ggactttttg acacgagatc acgaggtgta tccaggtttg
     7801 tccaaggagt ttagccgatg attgccaagg agtttgagac tttcttgttg gggcaggagg
     7861 aaactttttt gacccctgct aaaaatctag ctgtgttgat tgatactcac aatgcggatc
     7921 atgcgaccct cttgctcagt cagatgacct atacccgtgt tcccgttgtg acagatgaaa
     7981 aacagtttgt tgggacgatt ggactcagag atattatggc ttatcagatg gagcatgact
     8041 tgagccaaga aatcatggcg gatacggata tcgttcatat gacaaaaacg gacgtagcgg
     8101 ttgtttcgcc tgatttcacc attacggagg tcttgcacaa gctagtagat gagtccttct
     8161 taccggttgt ggatgcagag ggtattttcc aagggattat tacgcgcaag tccatcctca
     8221 aggccgttaa tgccctcttg catgacttta gtaaggaata tgagattcga tgccaatgag
     8281 agacaggatt tcagcctttt tagaggaaaa gcagggcttg tctgtcaatt ccaagcagtc
     8341 ctataagtat gatttggagc aatttttaga catggtaggt gagcggattt ctgagaccag
     8401 tctcaagatt taccaagccc agctagccaa tctaaaaatc agcgcccaga agcgaaagat
     8461 ttcggcctgt aaccaatttc tatactttct ctatcaaaaa ggagaggtgg acagctttta
     8521 ccgcttggaa ttagccaaac aagctgaaaa gaagacggaa aagccagaga ttctatacct
     8581 agactctttt tggcaggaaa gcgaccatcc agagggccgc ttgctagcgc tcttaatcct
     8641 agaaatgggg ctcttgccca gtgagatttt agccatcaag gttgcggaca tcaatctgga
     8701 ttttcaggtg ttgcgaatca gcaaggcttc ccaacggagg attgtcacca ttcccacggc
     8761 cttgctttca gaattggaac ccttgatggg gcagacctat ctttttgaaa gaggagggaa
     8821 accctattct cgtcagtggg cctttcgtca gttagaatct tttgtcaagg agaaaggttt
     8881 tccatcctta tcagctcaag tcttacgtga acagtttatt ctaagacaaa tagaaaacaa
     8941 ggtcgatttg tacgaaattg caaaaaaatt aggattaaaa acagtcctga ccttagaaaa
     9001 atatagataa tggatattaa attaaaagat tttgaaggac ccctggactt actcttgcat
     9061 ctggtttcta agtaccagat ggatatctac gatgtgccca ttacggaagt catcgaacag
     9121 tatctagcct atgtctcaac cctgcaggcc atgcgtctgg aagtgacggg tgagtacatg
     9181 gtcatggcta gtcagctcat gctgattaag agtcgtaaac tccttccgaa ggtagcagaa
     9241 gtgacagact tgggggatga cctggagcag gacctcctct ctcaaatcga agaatatcgc
     9301 aagttcaagc tcttgggtga gcacttggaa gccaagcacc aagaacgggc ccagtattat
     9361 tccaaagcgc cgacagagtt gatttacgaa gatgcggagc ttgtgcatga caagacgacc
     9421 attgacctct ttttggcttt ttcaaatatc ctagccaaga aaaaagagga gtttgcacaa
     9481 aatcacacga ctatcttgcg ggatgagtat aagattgagg acatgatgat tattgtgaaa
     9541 gaatccttga ttggacgaga tcaattgcgc ttgcaggatt tgttcaagga agcccagaat
     9601 gtccaagagg tcatcaccct ctttttggca accctagagt taatcaaaac ccaggagctg
     9661 atcctcgtgc aagaggagag ttttggagat atctatctca tggaaaagaa ggaagaaagt
     9721 caagtgcctc aaagctagac ttgatagaga ggaaagatga gtactttagc aaaaatagaa
     9781 gcgctcttgt ttgtagcggg tgaagatggg attcgggtcc gccagttagc tgaactcctc
     9841 tctctgccac cgacaggcat ccagcaaagt ttaggaaaat tagcccagaa gtatgaaaag
     9901 gacccagatt ccagtttggc tttgattgag acaagtggtg cttatagatt ggtgaccaag
     9961 cctcaatttg cagagatttt gaaggaatac tctaaggcgc ctatcaacca gagcttgtct
    10021 cgggctgccc ttgagacctt gtccattatt gcctacaaac agccgattac gcggatagaa
    10081 attgatgcca tccgtggggt taactcgagt ggagccttgg caaagttgca ggcttttgac
    10141 ctgataaagg aagacgggaa aaaggaagta ttggggcgcc ccaacctcta tgtgactacg
    10201 gattatttcc tagattacat ggggataaac catttagaag aattaccagt gattgatgag
    10261 cttgagattc aagcccaaga aagccaatta tttggtgaaa ggatagaaga agatgagaat
    10321 caataagtat attgcccacg caggtgtggc cagtaggaga aaagcagaag agctgattaa
    10381 gcaaggcttg gtgacggtta acggccaagt ggtgcgtgaa ctagcaacca ctatcaagtc
    10441 aggcgacaag gtcgaagttg aaggtcaacc tatctacaac gaagaaaagg tttactatct
    10501 gcttaacaaa ccacgcggtg tgatttccag tgtgacagat gataagggtc gcaagacggt
    10561 tgtcgacctc ttgcccaatg tcaaagaacg tatttaccct gtgggtcgtt tggactggga
    10621 tacatcaggt gtcttgattt tgaccaatga tggggacttt acagacgaga tgattcaccc
    10681 tcgtaatgag attgacaagg tttatgtcgc gcgtgttaaa ggtgtggcca ataaggacaa
    10741 tctccgcccc ttgacccgtg gtcttgagat tgatggtaag aaaaccaagc cagctgttta
    10801 tgaaattctc aaagtggacc cagtcaaaaa tcgctctgtg gtgcagttga ccatccatga
    10861 agggcgtaac catcaggtta aaaagatgtt tgaagctgtt ggtctccaag tagataagtt
    10921 gtctcggact cgtttcggac acctagactt gacaggactc cgtccaggag aatcccgtcg
    10981 tcttaataaa aaagaaatca gccaactaca caccatggct gtaactaaga aataatgaaa
    11041 cgaattttaa tagcgcctgt gcgcttttac caacgtttta tctcaccagt ctttccaccc
    11101 tcttgtcgct ttgagctgac ttgttccaac tacatgattc aggctattga aaaacatggt
    11161 tttaaggggg tattgatggg cttggctcgg attttacgtt gtcatccctg gtcgaaaaca
    11221 ggtaaggacc ccgttccaga ccacttttcc cttaaacgaa atcaagaagg ggaatgaggt
    11281 ggggtaaata gatttcaaaa tgataaaaac gcatcctatc aggtttgagt gaacttgata
    11341 ggatgcgttt tagaatgtca aaattttata ctcttcgaaa atcccttcaa accgcgtcag
    11401 ctttcatctg caacctcaaa acagtgtttt gagcaacctg cggctagttt cctagtttgc
    11461 tctttgattt tcattgagta ttaaattgag tttgaagtgg cttatttcaa agctttttgt
    11521 atgtcttcaa tcatgagttt tgttgattca agtccgcctc cgcttagata ccagaggtct
    11581 ggtgttagtt ggataatctt accattttta gcagcaggtg tttcagcgat aagggcattt
    11641 tctaggacac cgtcgttgct agagttgtcc ccaccgatgg caagggtacg gttgatgaca
    11701 aagaggatgt cagggttgat ttctttgaca ctttcaaagc tgacttcttg tccgtggcgt
    11761 gagtcttcaa atgttgtatc agttggtttg aatttcaagg tttggtacaa gaaagagaaa
    11821 cgagatttgg caccaaaggc tgccattttt ccttcattaa ggaggatcgc aagggccttt
    11881 ttgtcagagc tttcattttt agtagcgact tcttggatgc tcttgtctag cttggccaat
    11941 tcttccttgg ctttctgtgt accagtttcg ccgaaggcac ttgctaagga ttcgatatta
    12001 gccttggtag aagtccagta gtcgtccttg cttgcttgga agagaacggt tggggcgatt
    12061 tctttgaatt tgtctacgaa tttttgtgta cgtggtgaag cgataatcaa atcaggctca
    12121 agggcggcga tagcttctaa atcaggttct ttcatagaac caacattttt gacagttccc
    12181 actaggtctt ttagataagt cggaacagtt tttgtaggca ttccgacgat atttttttca
    12241 aatcctaaag cgcgaatagt atccgcagcg ccgaggtcaa aggtcacaat cttttcagga
    12301 actttggaaa gtttgacctc gtccagtgaa cttttaatgg ttacctctgt tggagcagag
    12361 ctactggtct ctgtctgact agtgcttgag tttgtactac atgcaccaag taggagcaag
    12421 aagctggcca ctagggcagt gaaataaagt ttaagggatg ttttcataat ttctcctttt
    12481 taaaatgtga taacgattta gggagtctct tgatcttatt gattaagaga ctgaaggttc
    12541 tctaacttga gcttttatgt tactagctat agatacagat ctttttgtca ttgatatcag
    12601 ctagcgtgat gggaatctca taaagttggc tgagcaggtc agcctgcatg atttgatcgg
    12661 tgcttccctt gctaaagacc tgaccgtcct tgaaggcgac aatttcatct gcatactgac
    12721 tggccatgtt gatatcgtgg aggacgatga taatggtctt gccgagttcc tccaccagtc
    12781 gtcgaagaat ttgcatcatg ctgacgcttt gcttgatatc gagattgttg agtggttcgt
    12841 ccagcaagat aaagtccgta tcctgggcca gtaccatagc gataaagacg cgctggagtt
    12901 gcccccctga caggctattg atgtagcggt cttttaagtt ggtcagttcc aaatagttca
    12961 gagtttctcg gattttttcc cagtcttctg atctaagtcg acctcggctg tagggaaaac
    13021 gtccaaaact gaccagttct tcaacagtca atttggcttg gtaattgatt ttctgtttta
    13081 ggatggttag ttcttgggcc agttcttgcg aattccagct ctcgatttca cgtcctttga
    13141 tactgagaac tccctgatct ttcttggtta gtctgctcat gatggagagg agagtcgatt
    13201 ttccagcacc atttggacca ataaaggctg tcagtttttg aggactgact tcaagcgaaa
    13261 tgccttgcaa aatatcctgt ttttgaatgg atttgtcaat gttttccagt ttcactgacg
    13321 agccctccta tatagtaaga taaagaataa gaagccaccc acactctcaa tgatcatact
    13381 gatacgaatt tccagtgcaa agactcgttc aatcaaggct tgccccaagg ttaagctaat
    13441 aaatccaacc agaatggcca ctataaagag taacttgtgc tgatagtctt tgacaatcag
    13501 gtaggtgagg ttggccagca taaagccgaa gaaggccata ggtcctacca aggcagtggc
    13561 cgttgaggtc aaaagcacga ttccccagag gagctctttc tgttcttttt caacatcgag
    13621 tcccaatatc tgagccgttt ctctttgcag gtgcaagaca tctagaacga ctgcttttcg
    13681 aaagaaaaag attgtcaaag cgaggatgat cagagaaccg atggctagga tggaagtgtt
    13741 aagatgttga aaggaggcaa aaagactatt ttgcagttta tcgtattcgt ttggatccat
    13801 taggacttga aggaaggtgc tgatatttcg aaagagactt ctgagcgcta gacagatcag
    13861 caggatgaag accaggtctt gcttcatcag tgtcttcaag taaccttgta aggcgagaaa
    13921 gaagagggac tggacaagaa gtaagactag gaattctaag ataggggatt tgccaagttg
    13981 aagaaacttg ctttcaaaaa ccagtagtag ggtttgtagt aggacgtaga aggattcaat
    14041 tcccaaaata ctaggcgtca ggaagcgatt ttccgtcaag gtttgaaaac taatggtcga
    14101 aatcccagtc gcgatggcta ccaagagata aacgatgatc ttttgggaac gcaacttcca
    14161 agcaaaggct gacaagtgag tgatgggcca aaagtagaga agacaagctc cgatggcaag
    14221 aataatgaga atccagaaga gcttggtatg tttgctttta gtctgcatct tttcgtcccc
    14281 ctctccagag aagtaggata aagacgagac taccgatgat tcctagcaag agactgacag
    14341 acaactcata gggcctaatc agaactcggg ataggatatc gcaagccaga actagattgg
    14401 caccaaccag tgcgaccatg agtttggttt gacttagatt atctccatag cacttgcgaa
    14461 caagattggg aacgataact ccgagaaatg gtaggccacc cacggtaatc atggtgacgc
    14521 ttgtcgttag cgccaccaga aagagggcca gtttttcaag tagggagtag gaaatcccca
    14581 aactctcgct ggtttctttc cctagattca tgatggtgaa ggtttgggat aatttccaaa
    14641 cggttatcag gatgatgagg cctaagaaga gccactcata ctgatgggtc tgaatcatgg
    14701 agaaggagcc ctgggtccag gcagtcatac tctgaaccag attgaaacga taggcgataa
    14761 cttctgtgac tgagccgata atcccgctat agatgatccc aatcagaggc aacatccacc
    14821 tttcctttac agtaaaaatg gtcataaagg ctaggaagaa gagggtgaat acgatggatg
    14881 aaacaaaagc gaagagcatc ttttgggtca gactagccga tggaaagaca aaaaggctca
    14941 gcaccattcc cagtttggcg gcttcagtcg ttccaactgt actcggtgca gcaaactgat
    15001 tttgggtaat agtctgcatg agaaggcctg ccatactcat actagaggca gtcaggagaa
    15061 tactgatagt tcttgggaga cgggactctt gaaagaggag ccaggtctgc tggtcgaaat
    15121 caaatagctt tccccatgaa aaatcactgg tcccaatgct aatagagaga aagactagga
    15181 gtagaagtaa gccaattaaa taatgagaaa gtttcatacc ccgtcctttc atgtagattt
    15241 ggtatcgaaa gatatctgcg gatataaatg taacattatt tttctaatct gtcaataaaa
    15301 tttctgacaa tttaataaat acaacaagga gagagcaaca agactttctc ctttgttatc
    15361 ctattctaaa atgtttttac cttaatctga taaaataata tcttcgaggg agtagctagc
    15421 cgtccaatca agatattgtt tagcttttga agcatctgct aggacactgg ctgggtcact
    15481 agcacgtcga gcaacaatct cgtgtgggat tttttaattt agtaattctt cagcagtttt
    15541 aaagatttct ttgatagtat agcctttttt agttcctaag ttaaagattt gagaagaact
    15601 gtcttcttga aataggtagt tcattccttt aacatgagcc tatgcaaggt ccaagacata
    15661 aatgtaatct cgaatacatg aaccgtcacg tgtatcgtag tcatctccaa atatttttaa
    15721 gctatcattt tgtcccaatg cggtcttgtt gatatttgga atgatgtgag ttggattttt
    15781 cacacgcaga ccgtttgaag catccatttc agccccagca acattaaagt aacggaaaat
    15841 aacatatttc cagtcgtagc gattggccat ccagtaaatc attcgttcgc ccatcagttt
    15901 tgtctctgta taagggttga cagggtcgat cagggtatct tcagtcgccg gcttgtcaat
    15961 acagttattt ccatagagag aagcagtcga agagaacatg attttttgag tgccaacttc
    16021 agataagact ttgagaactt ggttcctacc agcaacgttg gcagtgaagt atttacttgg
    16081 attttcaata ctttcgctca caacaatttc acctgcataa tggaggacag catcaatctg
    16141 attttctttt aagtaagcct ttaaggcgct agcatcataa acatccagtt ctttaaagct
    16201 agcacgacta tccacagccg ctcgatttcc tgtggagaga ttatcgagga catgcacctt
    16261 atagccagca tttaaaagag ctttaacggt atgggagcca atgtagctag tcccacctgt
    16321 aacaagaatt gttttggtca tgattttttc cttttctagt tttgtactat agtaaattga
    16381 aataagatat gaacaactct attaggaaag tcaaattaat ttctagaaat gttttagcag
    16441 ctacagcgta ctattccaaa ctcaaccaac tatatattta aagaaagaag aaagggaagt
    16501 caactatttt ctgtaaattt catgaaaaat ccaaacaact ttgatggtgt attgtttttt
    16561 gtttggaaat aaatattcga gttaattttg gaatgtttac tagattttgc actacatgca
    16621 agagaatact atccttttct aagatagagc aggactaaga tactaactta gaaatccacc
    16681 ttcccactat ccttctccta taaaaagtgg taaaatggat gaaagaaaga aggaactgaa
    16741 atgacaacat tattttcaaa aattaaagaa gtaacagaac ttgctgcagt ctcaggtcat
    16801 gaagcgcctg tccgtgctta tcttcgtgaa aagttgacac cgcatgtgga tgaagtggtg
    16861 acagatggct tgggtggtat ttttggtatc aaacattcag aagctgtgga tgcaccgcgc
    16921 gtcttggtcg cttctcatat ggacgaagtt ggttttatgg tcagcgaaat caagccagat
    16981 ggtaccttcc gtgtcgtaga aatcggtggc tggaacccca tggtggttag cagccaacgt
    17041 ttcaaactct tgactcgtga tggtcatgaa attcctgtga tttcaggttc tgttcctccg
    17101 catttgactc gtggaaaggg gggaccaacc atgccagcca ttgccgatat cgtttttgat
    17161 ggtggttttg cggacaaggc tgaggcagaa agttttggca tccgtcctgg tgataccatc
    17221 gtaccagata gttctgcaat tttgacagcc aatgaaaaaa atatcatctc aaaagcttgg
    17281 gataaccgct acggtgtcct catggtaagc gagctagctg aagctttatc aggtcaaaaa
    17341 ttcggcaatg aactctatct gggttctaac gtccaagaag aagttggtct gcgtggcgct
    17401 catacctcta caaccaagtt tgacccagaa gtcttcctag cagttgattg ctccccagca
    17461 ggtgatgtct acggtggtca aggcaagatt ggagatggaa ccttgattcg tttctatgat
    17521 ccaggtcact tgcttctccc agggatgaag gatttccttt tgacaacggc tgaagaagct
    17581 ggtatcaagt accaatacta ctgtggtaaa ggcggaacag atgcaggtgc agctcatctg
    17641 aaaaatggtg gtgtcccatc aacaactatc ggtgtctgcg ctcgttatat ccattctcac
    17701 caaaccctct atgcaatgga tgacttccta gaagcgcaag ctttcttaca agccttggtg
    17761 aagaaattgg atcgttcaac ggttgatttg attaaacatt attaaaccat aagggaggtg
    17821 gtagggatgg cagaaccaaa cctagaaagc cttataaaag atctttacaa tcatgctcga
    17881 catgatttga gtgaagattt agttgctgct ctcctagaga ctactaaaaa actgcctact
    17941 acaaatgagc aattgcaggc agttcgtctc tcaggcctgg tcaatcgtga attgctccta
    18001 aatcccaaac atccagcacc tgagttgctc aacttggctc gctttatcaa aagagaagaa
    18061 gccaagtaca gaggaactgc gacttctgca cttatgtatg aggaactttt taaaatgctt
    18121 tgattccatt gtggatcaaa gcatttttta taagacctat ctcgtgagcg ttcaaatagt
    18181 agtaacaagg aatcatgaga agtcagccga gaccatagta gtgaagaaac ttctgtaatg
    18241 gaagtggagt gaagtgagga atcgtcaaac ggtaggggat aggctgtttg aagggtgcta
    18301 cgaaaaagat agggtaaggt gaaattatag cggaatgaaa taagatatga acaaattgat
    18361 tagggaaatc aaatgaattt atagaaatct tttagcagtc atggtgtcct attccagttt
    18421 cgaaatgcta taaagacgaa caaattgatt gggaaattca aatcgctttc tatcaatgtt
    18481 ttagaagata cagtgcccta gtccaacttc aatatactat aaaagaacag atggaagcaa
    18541 ttatgattta cttctatctt taaaataaat gatctgatag gaaaaatgtg tcccctcata
    18601 aaaaatagga tagtacggat ggaaggcttt tgtagactgg aggacgaagg aatttagaaa
    18661 ctctcgttaa aagttagttg agccggagta tggtggtgtg aataattatc aaaaattatt
    18721 tccaaatcga aatagttgac agttagaacg atgagtgtta caattatttt attcatttcg
    18781 acatcgaaat aaattggagg tgttatgaaa gatagtcatt tgctagccca tcatattcgt
    18841 ttgttgaatg ggcggatttt tcaaaagtta ctgagtcaag atcctgaggc tctttatagg
    18901 ggtgaacagg gcaagatttt agcggtttta tggaatagtg aaactggctg cgcaactgcg
    18961 acagatatcg cgcttgcgac tgggcttgcg aataatacgc tgacgactat gataaaaaag
    19021 ctagaggaac aaaagcttgt aattgttagt ccgtgtggaa aagacaagcg taagaagtat
    19081 ttagttttaa cggagttagg caagtcccag aaagaagtgg ggcatcgtgt cagtcagaaa
    19141 ttggatacta tcttttacaa aggattttca gaggaagaaa ttcaccaatt tgaaggtttt
    19201 caagaaagaa ttttggcgaa tttgaaagag aagggaaatg aggtttagaa tatgtcacaa
    19261 caagtgaaaa atgctcacaa cctatacatc catgccattc aagacggacg agttgctgag
    19321 gctcaagccc agtctgtagg ggatacctat atccaacatt cgacaggtgt tcctgacggg
    19381 aaagaaggat ttgcagcctt ctttgcagat ttctttgagc gtcatccaga gcgtcagatt
    19441 aagattgtcc gcaccattga ggatggcaat ctggtctttg ttcatgttca tcaatatctg
    19501 aatggtggag aagctcaatg ggtgacgacg gatactttcc gtgcggatga gaatggtcgt
    19561 attgttgagc attgggatgt cattgactac tatcgaacac ctgaaaatga tcaactagat
    19621 caaatttttg gagattttga aatcaaggat ttggataaga aagcagaaaa taaaaagctg
    19681 gttcgccgtt tcttgacaga aattttccaa aatggggagc tagagcagtg gagtgattat
    19741 gtggcagacg atttgattca gcataatcat gagattggac aaggaagtgc tgcttataaa
    19801 aactatgtgg ctgaatatag tgtcactttt gactttgttt tccaactctt aggacaagga
    19861 aactatgtgg ttagctatgg tcagactcag attgatggcg ttgcttatgc ccagtacgat
    19921 atcttccgtt tagagaacgg gaaaattgtg gagcattggg ataataagga agtcatgcct
    19981 aaggtagaag acttgactaa tcgagggaag ttttaaattg aggacaaaga atgattgaat
    20041 acaaaaatgt agcactgcgc tacacagaaa aggatgtctt gagagatgtc aacttacaga
    20101 ttgaggatgg ggaatttatg gttttagtag ggccttctgg gtcaggtaag acgaccatgc
    20161 tcaagatgat taaccgtctt ttggaaccaa ctgatggaaa tatttatatg gatgggaagc
    20221 gcatcaaaga ctatgatgag cgtgaacttc gtctttctac tggttatgtt ttacaggcta
    20281 ttgctctttt tccaaatcta acagttgcgg aaaatattgc tctcattcct gaaatgaagg
    20341 ggtggagcaa ggaagaaatt acgaagaaaa cagaagagct tttggctaag gttggtttac
    20401 cagtagccga gtatgggcat cgcttaccta gtgaattatc tggtggagaa cagcaacggg
    20461 tcggtattgt ccgagctatg attggtcagc ccaagatttt cctcatggat gaaccctttt
    20521 cggccttgga tgctatttcg agaaaacagt tgcaggttct gacaaaagaa ttgcataaag
    20581 agtttgggat gacaacgatt tttgtaaccc atgatacgga tgaagccttg aagttggcgg
    20641 accgtattgc tgtcttgcag gatggagaaa ttcgccaggt agcgaatccc gagacaattt
    20701 taaaagcgcc tgcaacagac tttgtagcag acttgtttgg aggtagtgtt catgactaat
    20761 ttaattgcaa cttttcagga tcgttttagt gattggttga cagctctatc tcaacatttg
    20821 cagttgtcac ttttgacctt gttactagct attttgcttg cgattccctt ggctgttttt
    20881 cttcgctatc atgagaagct ggccgactgg gtcttgcaga ttgcaggtat tttccagacc
    20941 atcccgtctc tggccttgtt ggggctcttt atccctttga tgggaattgg gaccttgccg
    21001 gctttgacag ctctagtgat ttatgcgatt ttccctattt tgcaaaatac tatcactggg
    21061 ctgaagggaa ttgatccgaa cctgcaagag gctgggattg cctttgggat gaccagatgg
    21121 gaacgtctca agaaatttga aattccactc gccatgcctg ttatcatgtc tgggattcgg
    21181 acggcagctg ttttgattat cggtacggca accttggcgg ccttgattgg agcaggggga
    21241 ctggattcct ttatcctgtt gggaattgac cgtaataatg ccagtttgat tttgattggg
    21301 gcactttctt ctgcagtgct tgctatcgcc tttaacttcc tactaaaagt aatggaaaaa
    21361 gcaaaattac ggacgatttt ctcaggtttt gccttggtgg ctttattact gggtctgtct
    21421 tatagtccag ctcttttggc tcaaaaagag aaggaaaact tgattattgc tgggaaaata
    21481 ggcccagaac cagaaatttt ggctaatatg tataagttgc tgattgaaga aaataccagc
    21541 atgactgcga ctgttaaacc gaattttggg acgacaagtt tcctttatga agctctgaaa
    21601 aaaggtgata ttgacattta tcctgaattt accggtacgg tgactgaaag tttgcttcaa
    21661 ccatcaccca aggtgagtca tgagccagag caggtttatc aagtggcgcg tgatggcatt
    21721 gccaagcagg atcatctagc ctatctcaaa cctatgtctt atcaaaatac ctatgctgta
    21781 gctgttccga aaaagattgc tcaagaatat ggcttgaaga ccatttcgga tttgaaaaaa
    21841 gtggaagggc agctgaaggc aggctttacg cttgagttta acgaccgtga agatggaaat
    21901 aagggcttgc aatcaatgta tggtctcaat ctcaatgtgg cgactatgca gccagctctt
    21961 cgttatcagg caattcagtc aggggatatt caaatcacgg atgcctattc gactgatgcg
    22021 gaattggagc gttatgattt acaggtcttg gaagatgaca agcaactctt cccaccttat
    22081 caaggggctc cactcatgaa agaagctctt ctcaagaaac acccagagtt ggaaactgtt
    22141 cttaataaat tggctggtaa gattacagaa agccagatga gccagcttaa ctatcaagtc
    22201 ggtgtcgaag gcaagccagc agaacaagta gccaaggaat ttctacaaga acaaggtttg
    22261 ttgaagaaat gatgggacag agactttaaa catactgaac tcaacttcct taaacgacta
    22321 gataaaagaa tgctcagaca atttcgtctg ggcttttttg atgtgagaat gactgaatgt
    22381 cacttaaaat ggaaagaaag agaaaatttt catgattttc taaaatttta ctgtaaagac
    22441 agttgactat tcataaaata ggtgtataat attttgtgaa ctacttaaca aataagaggt
    22501 ttcagctcat gtcgactaag gttagaaatc ttgtgtatag gcagttcatt atctaataga
    22561 gcgttgcgtc cgaaagtcta tccagacacg gctctttaaa aacaaaagga gaaatgatgc
    22621 atacttattt gcaaaagaaa attgaaaata tcaaaacaac cctaggtgaa atgtcaggtg
    22681 gttaccgtcg tatggttgcg gctatggctg atttaggatt ttcaggaact atgaaggcta
    22741 tctgggatga cctctttgcc catcgtagtt ttgctcagtg gatttatttg ctggttttag
    22801 gaagttttcc tctctggctg gagttggttt acgaacatcg tattgttgat tggattggga
    22861 tgatttgtag cttgacaggg attatctgtg taatctttgt atcggaaggt cgagcaagta
    22921 attatctttt tggcttgatt aactctgtta tttaccttat tttggcccta cagaaaggct
    22981 tttatggtga ggtgctgacg acactttact tcacagtcat gcagccaatt ggacttctag
    23041 tttggattta tcaggcacag tttaagaagg aaaagcagga gtttgtcgcg cgtaaactgg
    23101 acggcaaggg ctggacaaag tatctttcca ttagtgtgct ttggtggttg gcctttggct
    23161 tcatttatca gtctattggt gccaatcgtc cctatcgtga ttcaatcaca gatgcaacca
    23221 atggggtagg gcaaatcctc atgacagctg tttaccgtga acagtggata ttctgggcgg
    23281 ctaccaatgt cttttcaatc tatctctggt ggggagaaag cctgcaaatt caagggaaat
    23341 atttaattta tctcattaac agtctagttg gttggtatca atggagcaag gcagctaagc
    23401 agaatactga tttacttaac taggaaaaga tgtttgaaag tgctgttttg agatttcgat
    23461 taaaacagat atagttgata atcaaggatt tatagtatga aaaagaggat cggcgggtcc
    23521 tcttttgttg ttgaaaagat aaaaaactca gtaatctaga aataagacaa ctgagcttta
    23581 ctctatattc aatttttagg aatgagaagg tctagataaa attggacaac ttcctggtct
    23641 gtgaaatctt gacctttttt gagccaccag gtcaatgtct cgataaagtt ggacatgacc
    23701 aagtgttgga ggtaagaagt aggcagatta gggtgggctt cttttaaatt atcagctagc
    23761 acggaataga catggtgttc tagctcttta tggagttgac ggaggaagta gtcatttttg
    23821 gaaaatagca gactggtgat atggtcttgg tttttatgaa aatgcagaaa gaggtgggcg
    23881 aggtagtcct cggttgaaat ggcttgctct ctttcaaaaa gatgatggaa gaggtagcgg
    23941 cagagctggt ccagaagaag ctccttactc tcatagtgac agtaaaaggt ggatcgtccc
    24001 acatctgcga gatcaatgat atcctgaaca gtagtggcct cgtagccctt agcattcaaa
    24061 agttgtataa aagcttgata gatggctttt ttggttttgc tgatacggcg gtcaatgtta
    24121 gtcatatgga cacttgaggc aaattgttca gaactgaata aagctgacgt tttgcttcta
    24181 tcctttcttt gagttttagt ggataatgat aatgaacaag gtgttcataa atctattata
    24241 acaaaggaat gagaaatatg aaggcaaaat atgctgtttg ggtggctttt ttcttaaatt
    24301 tgacttatgc cattgttgag tttattgcag gtggagtatt tggttctagc gctgttcttg
    24361 ctgactctgt gcatgacttg ggagatgcga ttgcaattgg aatatcagct tttctagaaa
    24421 caatctccaa tcgtgaagaa gacaatcagt acaccttggg ctataagcgg tttagcctgc
    24481 taggagcctt ggtaacagct gtgattctcg taacgggctc tgttctagtc gttttggaaa
    24541 atgtcacgaa gattttgcat ccgcagccag tcaatgatga ggggattctc tggttaggaa
    24601 ttattgcgat tactatcaat ctgttagcga gtctggtggt tggtaaggga aagacaaaga
    24661 atgagtctat tctgagtctg cattttctgg aagatacgct agggtgggta gctgttatcc
    24721 tgatggcgat tgttcttcga tttacggact ggtatatcct agatcctctt ttgtcccttg
    24781 tcatttcttt ctttattctt tcaaaagccc ttccacgttt ttggtctaca ctcaagattt
    24841 tcttggatgc tgtgccagaa ggtcttgata tcaagcaagt aaagagtggc ctggagcgat
    24901 tggacaatgt ggccagcctt aatcagctta atctctggac tatggatgct ttggaaaaaa
    24961 atgccattgt ccatgtttgt ctaaaagaaa tggaacatat ggaaacttgt aaagagtcta
    25021 ttcgaatttt cctaaaagat tgtggttttc aaaatattac cattgaaatt gatgctgacc
    25081 tagaaactca ccaaacccat aagcgaaagg tgtgtgactt ggaacggagt tatgagcacc
    25141 aacattagaa aaaagtgaaa aatacttggg tactatctta tttggaatag agtaatttct
    25201 ttattattta aatatttcaa aaattggtaa gagaagagca ttgtataaac tccatatata
    25261 tgattgttaa tgataaaaat ttttcgatta gatacaaaat gcttgacttg gagtcaactc
    25321 aaagttatat aataagataa gtgagttaga atagcgtgaa ttcagtgaat gaaatgagag
    25381 gaggttagcg tgtgaatatt aaatctgcca gtgatttgtt gggaatttca gcggatacga
    25441 ttcggtatta tgaacgggtt ggtcttgtgc caccgattac tcgtactgct actgggattc
    25501 gtgattttca agatcaggat atcgaagcgc tggaatttat taagtgtttt cgttcggcgg
    25561 gtgtctctgt agatagttta gttgactata tgtcgctcta ccaaaaggga gatgaaacga
    25621 gagaggagag gcttggtatt ttagaagagg aaaagcaaaa attagaggag cgcttgtctc
    25681 agctacagac agctttaaat cgtttaaatc tcaaaattaa actttataag gaaggaaaat
    25741 tttaaatgaa atcagcagta tatacaaagg caggtcaggt tggacttgct agcattgaac
    25801 gtccgcaaat aatagaagcg gatgatgtga ttattcgtgt ggttcgtgcg tgcgtttgtg
    25861 gttcagattt atggaggtac cgtaatccag aaacgaaagc tggacacaaa aatagtggac
    25921 acgaagcgat tgggattgtt gaagaagctg gggaagccgt tacgacggtg aaaccaggtg
    25981 attttgtgat tgtccctttt acacatggat gtggtgagtg tgatgcctgt cttgctggat
    26041 ttgacggttc ttgcgacaat catattggca ataatttggg gggtgatttt caggcagaat
    26101 atattcgctt ccactatgca aactgggcgc tggttaaaat ccctggtcaa ccttctgact
    26161 atacagaagg gatgctccag tcccttttga ctcttgcaga tgtcatgccg acaggctatc
    26221 atgcggcgcg tgttgcaaat gttcaaaaag gggacaaggt tgttgttatc ggtgatgggg
    26281 ctgttggtca atgtgctgtc atcgcggcta agatgcgtgg agcatcacaa attatcctta
    26341 tgagccgtca tgaagaccgt caaaagatgg ctatggagtc aggtgcgaca gctgttgttg
    26401 cagaacgtgg tcaagaagga attaccaagg tgcgtgaaat cctcggtgga ggagcagacg
    26461 cagcacttga atgtgttggt acggaggctg ctatagaaca ggcgctaggt gttcttcata
    26521 atggagggcg tatgggcttt gtaggagtcc cacactataa taatcgtgct cttggttcga
    26581 catttatgca aaatatctct gtagcaggtg gggcagcttc tgctacaaca tacgataagc
    26641 aatttttact aaaagccgtc cttgatggtg atatcaatcc aggtcgcgtc tttacttcaa
    26701 gttataaact ggaagatatc gaccaggcct ataaagatat ggatgaacgt aagaccatta
    26761 agtctatgat tgtaatcgaa taaaaaacga ataggagttt tagaactcta ttcgtttttt
    26821 atgttatcct attcttgatt tagggtactt tctcttaatg tcagtctggt tcccagcatg
    26881 gtcaggctag ggattttccg accgtggagg acttccttgt taagaatatc catacctgct
    26941 cgccccattt cttcagtata gactgtgatg ctggagaggg gaggataaac ctgcttggtc
    27001 agactggtgt cgttgaatga aatgaggctg acgcgatctg gcaggctgat tccagcttct
    27061 tggagggcac ggagggcacc gatagctaaa ctatcgctgg ctgcgaaaaa tgctggcgga
    27121 agttggtctc ccaagctctg aatggcctcc ttcattaagt catagccaga ctgggcagta
    27181 aatcttcctt gaaagaccag ttcatcatga tagattcccc tcgcttgact gtagtttttg
    27241 aagttttcta gacgcttgtc ctgaatgatt tcttcttggt ctgttgtttc ctcaagccct
    27301 gttagaatcc cgatgcggtc catcccttga ctgaggaaat aatcgacaac ctgtttcata
    27361 gcagtgtaaa aatccgtgat aatacaggta tgtcccaggg aaagtgtatc gctgtctaga
    27421 aatacaagag gcttttggta ttcttcaaag gcagaaatct gagctcggct aaattttccg
    27481 atgcagagaa tcccaatcac ttcctcgctt aaggtaaaag gatggtcatt aaaatagcgc
    27541 aagatatcgt agtccaactc ttgggctctt ttttctattc ctaggcgaat ctggtagtag
    27601 tagaggtcgt ctagctcccc ttgttcgctg acccattgga taatggcaat cttttgcttg
    27661 ggcttgtggg actcgcctgt cttgaggtgt ttggtgtagc ctaactcttc agcaacggtt
    27721 aaaatacggt gtctggtttc ttctgtaaca gataggctct ggtcgcggtt gaggacacgg
    27781 gatacggtcg cgattgagac agaggctagc tgtgcaatgt cttttaaggt agccataaat
    27841 cctccttgat taggttagta tatcatattt ttcttctttt tactgatatt ttagtaaaat
    27901 tttagtaaaa aggattgacc ttgggaaatt tcttggatac aatagaaaga aaacgattac
    27961 acgttaagat ggcttaacgg acagtcaaag gagaattcat atggcacaac atcttactac
    28021 tgaagtcctt cgcaaagact ttcttgctgt ttttggtcaa gaagcagacc aaaccttctt
    28081 ttcaccaggc cgtattaatt tgattggtga acacacagac tacaacggtg ggcacgtttt
    28141 tcctgctgct atttccttgg gaacttacgg tgcagctcgt aagcgtgacg accaagtctt
    28201 gcgtttctac tcagctaact ttgaggacaa gggcattatc gaagtgcctc tcgctgacct
    28261 caagtttgaa aaagagcaca actggaccaa ttatccaaaa ggtgtccttc atttcttgca
    28321 agaagctggg cacgtgattg acaaaggttt tgatttttat gtttatggga atatcccaaa
    28381 tggtgctggc ttgtcttctt cagcatcctt ggagctcttg acaggagtcg tggcagagca
    28441 tctctttgat ttaaaattag agcgtctcga tttggttaaa atcggaaaac aaacagaaaa
    28501 caactttatc ggagtcaact ctggtatcat ggaccagttt gctattggta tgggggccga
    28561 tcaacgtgct atttaccttg ataccaacac cttagagtat gatttggtgc cacttgattt
    28621 gaaggacaat gtcgttgtta tcatgaacac caacaaacgc cgtgaattgg cggactctaa
    28681 atacaatgaa cgtcgtgctg agtgtgaaaa agcagtggaa gaattgcaag ttgccttgga
    28741 tattcagacc ctgggtgaat tggacgagtg ggccgttgac caatatagct atttgattaa
    28801 agatgaaaat cgtttgaaac gtgctcgcca tgctgtgctt gaaaaccaac gtacccttaa
    28861 agctcaagca gcccttcaag caggtgattt ggaaacattt ggtcgtttga tgaatgcgtc
    28921 acacgtttct ctggagcatg attatgaagt aactggtttg gaattggata ctcttgttca
    28981 cacagcttgg gcacaagaag gagttctcgg tgctcgtatg acaggggctg gttttggtgg
    29041 ctgtgccatt gccttggttc aaaaagatac tgttgaggcc tttaaggaag ctgtaggcaa
    29101 acactacgag gaagtagttg gatacgctcc aagcttctat atcgctgaag ttgcaggtgg
    29161 cactcgcgtc cttgactagt caaaaggagg ctctatagtg atcttagtag ataaatttgt
    29221 aacacatgtc atttctgaaa gttcatttga ggaaatggat cgaatctacc tgaccaatcg
    29281 tgttttggca cgagtgggag aaggtgtttt ggaagttgag accaatctgg ataaattgat
    29341 tgacctcaag gaccagctag ttgaggaagc cgttcgatta gagacgattg aggatagtca
    29401 gactgcgcgt gaaatccttg gtactgaatt gatggacttg gtgactcctt gtccgagtca
    29461 ggtcaatcgt gacttctggg aagcctatgc ctactctcct gagcaagcga tagaggattt
    29521 ttatcaactc agtcagaaaa atgactacat caaactcaag gccattgcta aaaatatcgc
    29581 ttatcgtgtt ccatctgatt atggagaact tgaaattacc atcaatctct ctaagcctga
    29641 aaaggatccg aaagagattg cggcagccaa gttggtgcaa gctagtaatt atcctcagtg
    29701 tcaactttgt ttagagaatg agggttacca tggtcgggtc aaccacccag ctcgcaccaa
    29761 ccaccggatt atccgttttg aaatggttgg tcaggaatgg ggtttccagt attcgcccta
    29821 tgcttacttt aatgagcatt gtatcttttt agatggccag catcgtccca tggccattag
    29881 tcgtcagagt tttgaacgtc tgttggctat cgtagagcag tttccaggat attttgctgg
    29941 atctaatgcc gacctgccga ttgtgggggg ctctattcta actcatgatc attatcaggg
    30001 aggccgtcac gtatttccta tggaattggc tcccttgcaa aagaccttcc gatttgctgg
    30061 ttttgagcag gtcaaggctg gaattatcaa gtggccaatg tctgtcctac gcttgacttc
    30121 ggattccaaa gaggatttga ttaacttagc tgataagatt ttccaggaat ggcgtcagta
    30181 ttcagattct agtgtgcaga ttttagcaga gacagacggg acaccgcatc acaccatcac
    30241 accaatagcg cgtaagcgtg atggacagtt tgagttggac ttggtcttgc gagacaatca
    30301 gacttcagca gagcatcctg atggcatcta tcatccccac aaggatgtcc aacatatcaa
    30361 gaaggaaaat atcggcttga ttgaggtcat gggcttggca atcttgccac cacgtctgaa
    30421 agaagaagtg gagcaagtcg ctagctatct tgtaggagaa gctgttacag ttgccgatta
    30481 tcatcaggag tgggcagacc aactcaaatc ccaacatcca gacctaacgg ataaagaaaa
    30541 agcccttgca atcgtcaagg attctgtggg ggctatcttt gtgcgtgtac ttgaggatgc
    30601 aggagtctac aagcagacag agcagggaca ggcggccttt atgcgctttg tggaacaggt
    30661 cggaatttca ctagactagg agctttctcc ttgcacagtc ctataaaaag tagtatcata
    30721 gtgtcgtttg aaatatcagg aggaaacgat gaaagacttt cattttgacg ctatatctgc
    30781 ctttgaaaat tacgaaattg aaaaaatgag agatggtcac gttgtggtga cgaccaaagt
    30841 agtgaactcg tcgctcaact actatggcaa tgcccatggt ggctatctat tcacgctatg
    30901 tgaccaaatc agtggtttgg tggttatctc gctgggactt gatggggtga cactccaatc
    30961 ctctatcaac taccttaagg caggaaaact cgacgatgta ttgaccatta aaggagaatg
    31021 tgtccatcaa ggtcgtacaa cctgtgtaat ggatgtggat atcaccaatc aagaaggcag
    31081 aaatgtctgc aaagcaacct ttaccatgtt tgtcacaggc cggcggtcag aagacagaca
    31141 ggtaaggata taaagagtaa tttaatagag tgaggtgaat tttggaattt ataagatttg
    31201 ccttactcat tttttgatat tgatatgatt taattctaaa atagaaaatt tagtaatgtg
    31261 gtagaaaata caagagttgt gttttaattt ctatggtata attaaaagca tgaagataaa
    31321 agaaataaag aaagttactt tacaaccgtt cacgaaatgg acaggtggta aaagacaatt
    31381 attgcctgtt attagagaat taatacctaa aacctataac aggtatttcg aaccttttgt
    31441 tggaggtgga gctttatttt ttgatttggc tcctaaagat gcagttatta atgattttaa
    31501 cgctgaacta ataaattgct atcaacaaat taaggacaat cctcaagaat tgattgaaat
    31561 tttgaaagtt catcaggaat ataattcaaa agaatattat ttagatttac gttctgcaga
    31621 tcgtgatgaa agaatagata tgatgtccga agtacaaaga gctgcacgta ttctatatat
    31681 gttgagagtg aactttaatg gtctatatcg tgtgaattct aagaatcaat ttaatgttcc
    31741 atatggacgt tataagaatc ctaaaattgt tgatgaggaa ttgatatctg ctatttcagt
    31801 ttatataaat aacaatcaac tagaaattaa agtgggagat tttgaaaagg caattgtaga
    31861 tgttcgaaca ggagattttg tgtattttga ccctccatat attccattgt ctgagacgag
    31921 tgcatttacg tcttatactc atgagggatt ctcttttgca gatcaagtaa gattaagaga
    31981 tgcctttaag agattgagtg atacaggagc ttatgttatg ttatcaaatt cttctagtgc
    32041 tttagtagag gagttgtata aggattttaa tatacattat gttgaagcta cccgaactaa
    32101 tggagcaaaa tcttcaagtc gaggaaaaat ttctgaaatt atagtcacaa attatgaaaa
    32161 ataacgaata taagtatgga ggtgttctta tgacaaaacc atactacaat aaaaataaga
    32221 tgattcttgt tcattcagat acgttcaagt tcttatcaaa aatgaaacca gaaagtatgg
    32281 atatgatttt tgctgatcca ccttattttt taagtaatgg tggaatatct aattctgggg
    32341 gacaagtagt ttctgttgat aaaggagatt gggataaaat ttcttcattc gaagaaaaac
    32401 atgagtttaa tcgtaaatgg attcgcctag caaaagaagt tctgaagcct aatgggacgg
    32461 tatggatttc aggtagtttg cacaacatat actcagttgg aatggcatta gaacaagaag
    32521 gttttaaaat tctgaataat attacttggc agaaaacaaa ccctgccccc aatttatctt
    32581 gtcgttattt tacccattct actgaaacca ttttatgggc cagaaaaaat gataaaaaag
    32641 ctcgtcatta ctacaattat gatttaatga aagaattgaa tgatggaaaa caaatgaaag
    32701 atgtctggac cggttcttta acaaagaaag ttgaaaaatg ggctgggaaa catccaactc
    32761 aaaaaccaga gtatttgtta gaacgtatta ttttagcctc tactaaagag ggtgactata
    32821 ttctagaccc atttgttggt agtggcacta cgggtgttgt tgcgaagcgg ttaggtagaa
    32881 gatttatagg tatcgatgct gaaaaagaat atttaaaaat tgcaaggaag aggttggagg
    32941 cagaaaatga aacaaactag aaattttgat gagtggttgt caacgatgac cgacacagta
    33001 gctgactgga cttattatac agattttcct aaggtttata aaaatgtatc tagtataaaa
    33061 gttgctctaa atattatgaa tagtcttatt ggtagtaaaa atatacaaga ggatttttta
    33121 gacttatatc aaaattatcc agaaattttg aaagttgtgc ctctacttat tgctaaacgt
    33181 ttgagagata cgattattgt taaggatccg ataaaagatt tctattttga ttttagtaaa
    33241 cgaaactata gtattgaaga atatactatg tttttggaaa aatcaggtat atttgattta
    33301 ttgcaaaatc atttagtatc aaatttagtt gactacgtta caggtgttga ggttggtatg
    33361 gatactaatg ggcgcaaaaa tcggactgga gatgcgatgg aaaatattgt tcaaagctat
    33421 cttgaagctg aagggtatat tttaggagag aatttattta aagagattga acaaaatgaa
    33481 atagaggaaa ttttttctgt cgatttatct gctattacga atgatgggaa tactgtgaaa
    33541 cgttttgatt ttgtcataaa aaatgaacaa gtgctttatc tgattgaggt taatttttat
    33601 tcaggaagtg gttcaaaatt aaatgagacg gctagatctt acaaaatgat tgctgaagaa
    33661 actaaagcta ttcctaatgt tgagtttatg tggattactg atggacaagg ttggtataag
    33721 gctaagaata atttacgaga aacatttgat attttaccat tcttatataa tattaacgat
    33781 ttggaacata atattttaaa gaatttgaaa taggtccaat tcaattagat gggaattggg
    33841 attgattgta tttataatca atttgtgata aacaaaaaag aggctcgcac ctctttttct
    33901 tatttctttt tatgatttaa tacggcattg aggacaatag cgagtaggct ggctacgacg
    33961 attccgtttg agaagaacat ttggaaggct gtcggcatgc tgacaaagag attactgttg
    34021 ttgagaccga cacctgcagc gattgaaaca gctgcgataa ggaagttgtg ttcattgtta
    34081 gcaaagtcaa ctcgggcgag gatttgcatc ccttgaatag atacaaaacc aaacatcacc
    34141 agcatggcac cgccgaggac ggagcttgga atgatttggg caagggcacc aaacttagga
    34201 agcagtccaa ggagaaccag gaaaccagct gcgtagtaga ttggcaggcg ttttttgatg
    34261 cctgacaatt taaccaaacc aacgttttgt gaaaatccgg tgtaagggaa ggtgttaaag
    34321 attcctccga gaagtaccgc caaaccttct gcgcggtaac cgttgcgaag gcgcgtgctg
    34381 tcgattggat cttttgtgat atcagacaag gctagataaa caccagttga ctcaaccata
    34441 gacaccgttg cgatgataca catcatggca atagatgaga tttcaaaggt tggcatccca
    34501 aagtagagtg gagttgggac atggacaagt ggagctaccg caacaggaga gaagtccacc
    34561 aagcccatag tagcagcaat ggcagttcca acaaccagac caatcaaaat agagatagac
    34621 ttgataaatc ctttggtaaa gatgttgatc aagaggataa tcagaacagt aatagctgca
    34681 agcaagagac tttgaccagt tggctctgga acgttatttc ccatatttcc aatagcgaca
    34741 gggatcaagg ttaaaccaat cgtggtaata acagatcctg ttacgataga tgggaagaga
    34801 ttggctactt ttgagaagat gcctgaaaca agaaccacgt aaatcccaga tgcgataagg
    34861 gcaccaaaca tagcgccact accatggctt tgcccaatca taatcaaggg agcgaccgac
    34921 tggaatgcaa ctccaagaac gactgggagt ccaatcccaa agtatttgtt gagttggagt
    34981 tggaggaagg ttgccacccc acacatgaag atatctgtag aaatcaggta ggtcaactgc
    35041 tcagctgaat agccaagggc tgtcgcaatc atgatgggaa ccaggataga tcctgagtac
    35101 atggctagta agtgctgcaa gccaagaacg gctgcttgcg agtgtttttc ttgagtttgc
    35161 attagagatc tgcctcctta aatacgacct gaccattttc aaaacgatcc aaacgagcaa
    35221 gtgataggac agggtagcct gctttttcaa gcaaatcacg gccatcttgg aaggatttct
    35281 caatcacgat accgatagct tggactgtgg caccggcctg ttcgatgatt tgaatcaagc
    35341 ctttagcagc ttggccatta gcaaggaaat cgtcgataat caaaaccttg tcctctggtg
    35401 agaggaattt tccagcgata gaaacggtgc tggtcacctg tttggtaaag gagtagactt
    35461 gagcagttaa gatgccttcg ttcatggtga tgttcttagc ttttttggcg aaaatcatgg
    35521 gaacgtttaa ggcttcagct gtaaaaacgg ctggggcaat acccgatgct tcaatggtta
    35581 cgaccttggt aatgccagta gcagcaaatt tttccgcaaa aaccttacca atctctcgca
    35641 tcaagctaaa gtcaacttgg tgggttaaaa aggaatctac cttgaggatg ttatcaccca
    35701 agatatgccc atccttgagg atgcgttctt ctaataattt cataagacct cctaaagtct
    35761 aaaagttaat ttacttgttg tttaaatgtt tctatagtga tcccttttgc taatactata
    35821 tatttgataa aactattacg agcgaagcga gtcttatcaa atatttcccg ttgtagtggt
    35881 atcatagaca ataatcttgt tattgtctat gacgggattt ttgagagtaa aatagttcgg
    35941 ggaactattt tagcctaagc ctagaaatga aagagctagg ggctcaaaaa ttagggatga
    36001 aattccctgg attcctgaaa ttattcacag gataatttca cctcccgtcc gcactaatta
    36061 agggaaatat taaaaatatt caaaaaagac ctacttaatc tctaagtaag tcccccaaat
    36121 agacatggca aaaacggcca tatctcactg ctgacttact tattgttagg tgttccggca
    36181 ccttgtagaa acgtcgtgcc aattcacgac ataaacaagt aaaacgatat tcaattttaa
    36241 ataggcttga gcaaatgttt ttattttaca ctaaataact ttagaaatca actattttgt
    36301 tagtattttg gtttaaaaaa cgaacaaaca gaagagaggg gtgaacaaaa actccgttgt
    36361 aagctaacat ttatactaaa tgaaaatcaa agagcaaact aggaagctat ccacaacctc
    36421 aaaacattgt tttgaggttg tggatagaat tgacagagtc agtatcatat acctacggta
    36481 aggcgacgtt gacgtggctt gaagagattt tcgaagagta ttagaagatt tttccatcat
    36541 aaaaggcata ctatcaagtt tttagacacc tgacaatatg cctttttcta actttaaaga
    36601 cttttcccaa tttttattat tctactcgct aaatcttaaa aaatagctat ctggatccaa
    36661 aactgcaaat tcatgaggat agatatagtg atcactgaca cgaaactttc ttttggtcaa
    36721 gggacgataa ataggatagt ttgccttcat cactctttga tagagttttg aaacatcctt
    36781 tatgccaaag gagagattga ctccacgacc aaatagatag gtcagttcag ctagttgatc
    36841 ctttgttccc tcctctaaca ttagttgaca ctcttcaaga gaaagagaaa gttttcttct
    36901 ggacgttggt attcaatcct aaaacccagt aaatcacagt agaaggaccg ggactgttcg
    36961 atattcgata caagcaactc gggaatgacc gcattgtagt ccatatagaa aatccttaca
    37021 agtcaatttc caagacaatc ggtgtatggt cttggcgagc acctgagtca atcatatcag
    37081 atttagtgac cttgtcagcg atacggttac ttgtgagcca gtagtcgatt ctccagcctg
    37141 tattgttgat tttagaagtt ttgctgcgtt gtgcccacca agtgtagcgt tcaggaacat
    37201 cgccatgaac atggcggaag gtatcagtaa atccagttgc caataggttg gtaaatccag
    37261 cacgttcctc gtcagtaaat ccaggtgaac ggcggttgct agcaggattt gcaaggtcga
    37321 tttcattgtg ggctacgttg tagtcaccgg tcgcaaggac tggtttttct ttgtctagtt
    37381 cagccaaata ctcagcatat ttaacatccc agacttggcg ttcttccaag cgtttaagac
    37441 catcgccagc atttggtgtg taaacttggg tcacgaaaaa tgcatcaaat tctagagtga
    37501 tgatgcggcc ttccaagtcc atggtagaag gggcaccgat ttctgggaaa gtgacagtgg
    37561 gtgtaagttc tttcttataa aggaacatgg ttccagcata gcctttacgg gcaggctctt
    37621 gggaagagcg ccacgtgttt tcgtagcctg ggaagagttc ttctaaaatt tccacgtgtt
    37681 tctttgtagg tcctttggca gaaagcttgg tttcttggat agcaatgata tcagcatttt
    37741 cagcgaccaa ggtttgtagg acttcttggg acaatttggc acgagctgag tcactagtta
    37801 gggcagcgtt tagggaatca atattccatg agataagttt cataaagtta ccttttcatt
    37861 cagattatag attttattat accaaaaaaa gatctatttc cccaacgtat ggtttgaaaa
    37921 attactctct ttcgtttata attaagaatg attttatgaa agggagtgaa aatacatgaa
    37981 attctactct tatgactatg tactcagcca aatcggtcag caaaatggta tcatggttgg
    38041 ctttgggatt gttctattag ctatgacagt ttttttgctt tcaaggcata ccatgataaa
    38101 aagggaaccg aatttcgtga gttggtcatg atttcagctc tggccttatt tagctctgct
    38161 tttggtcagc atcacgactt atcaaaacaa tcaagtttct aacaataaat ttcaaacttc
    38221 acttcatttc atcgaggttg tttccaaaga tttgggagta gacaagtcag aagtctatgt
    38281 taatacttcc acaaacacag atggcgcact tatcaaggtg ggagatcgct attatcgtgc
    38341 cctaaacgga agtgagccag acaagtacct gttagagaaa gtcgaattgt ataagacaga
    38401 cgcaattgaa ctggtggatg tgaacaaatg acacttaatt atatcgaaat tttaatcaaa
    38461 ctggtcttga ctctcaaata gctcaacaac aatgttcact ttgtgaaacg tttgattgat
    38521 ggtaagccaa ctctccttat caaaaatggg aatattgacc cataagcctg tcgttcagtt
    38581 ggtttgtctg catcggatgt agccctcaaa cttcgtggcc aagggatttt ccagatgaag
    38641 caagtcaaac gagctgtgca agagcaaaat gggcaactca tcgttgtgca aatgggagat
    38701 gaaaattcta agtatccagt tgtgactgac ggtgtgattc aagtagatgt cttggaatcg
    38761 attggtcgta gcgaagagtg gttgcttgat aacctcagta aacaagggca tgacaatgta
    38821 gccaatatct ttattgctga atatgacaag ggtgctgtta cagtcgtaac ttatgaataa
    38881 gaaaaacctg gggtcttgta ctcttcgaaa atctcttcaa accgcgtcaa cgtcgccttg
    38941 ccgtatgtag gttactgact tcgtcagttc tatctacaac ctcaaagcag tgctttgagc
    39001 agcctgcggc tagtttccta gtttgctctt tgattttcat tgagtattgg cttcaggttt
    39061 ccatttgcaa tcagaaaggg attttatgtc cattattcaa aaactttggt ggtttttcaa
    39121 gttagaaaaa cgccgttatc tagtcgggat tgtggccctg gtcttggttt ccgttctcaa
    39181 tctcattcct cctatggtta tggggcgggt cattgatgcc atcacatcgg ggcaattaac
    39241 ccagcaggac ctccttctta gcctatttta cttgctactt gcagcctttg gtatgtacta
    39301 tttgcgctat gtgtggcgta tgtatatcct tgggacctct tattgcttgg gacagatcat
    39361 gcggtctcgc ttgtttaagc atttcacaaa aatgtcatca gccttttatc aaacctatcg
    39421 gacgggtgat ctgatggcac acgcaaccaa tgatatcaat gccttgactc gtttagcagg
    39481 tggcggtgtc atgtctgcgg tggatgcctc tatcacggct ctggtgactt tgttgaccat
    39541 gctctttagc atctcatggc agatgactct tgttgccatt ctccccctac ctttcatggc
    39601 ctatgcgact agtcgcctag ggagaaagac tcataaggcc tttggcgaat cccaagctgc
    39661 tttttctgaa ctcaataaca aggtacagga gtccgtatca ggtatcaaag tgaccaagtc
    39721 tttcggttat caggcagacg agttgaagtc ttttcaggca gtcaatgaat taaccttcca
    39781 aaagaacctg caaaccatga aatatgatag tctctttgac cctatggttc tcgtgtttgt
    39841 tggttcgtcc tatgttttaa cgcttttggt tggctccttg atggttcagg aagggcagat
    39901 tacagttggg aatctagtca cctttatcag ctatttggat atgctggtct ggcctcttat
    39961 ggccatcggc ttcctcttta atactactca gcgagggaag gtttcttacc agcggattga
    40021 aaatcttttg tctcaggaat ctcctgtaca agaccctgag tttcctctgg atggtattga
    40081 aaatgggtgt ttggagtatg ccattgacag ctttgctttt gaaaatgagg aaacactgac
    40141 ggatattcac tttagtttgg caaaagggca aacactgggc ttggttgggc agacaggctc
    40201 tgggaaaacg tccttaatca agctcctctt gcgtgaatac gatgtggata agggtgccat
    40261 ttatctaaac ggtcacgata ttcgggacta tcgtctgaca gaccttcgca gtctcatggg
    40321 ctatgttcct caggaccagt ttctctttgc aacttcaatc ctagacaata tccgctttgg
    40381 caatcctaac ttgccccttt cagcggtcga ggaagctact aagctagccc gagtttacca
    40441 agatattgta gacatgcctc aaggatttga tacgctgatt ggtgaaaaag gagtcagtct
    40501 ttctggtggt caaaagcaac ggttggctat gagtcgggct atgattttag accctgatat
    40561 cttgattttg gatgattcct tatccgccgt agatgccaag acagagtatg cgattatcga
    40621 caacctcaag gagacgcgaa aggacaagac aaccattatc actgcccatc gcctcagtgc
    40681 tgttgtccat gcagatttta ttttagttct acaaaatggt caaattatcg aacgaggcag
    40741 gcacgaagac ttgctagcga tggatggctg gtatgcccaa acctaccagt ctcagcagtt
    40801 agaaatgaaa ggagaagaag atgcagaata aacaagaaca atgggctgta ttgaagcgct
    40861 tgatgtctta tctcaagcct tatagactcc tgaccttttt ggcactcagt tttctcctag
    40921 cgacgacggt cattaaaagt gtcatacccc tcgtggcttc ccactttatc gaccagtatc
    40981 tcagcaatct taaccaacta gccgttaccg ttttgctggt ctactatggt ctctacatcc
    41041 tacaaactgt agttcagtat gtaggcaatc ttctctttgc gcgcgtgtct tacagtattg
    41101 ttagggatat tcgtcgggat gcctttgcca atatggagaa actgggcatg tcttactttg
    41161 acaagacgcc agcaggttct atcgtttctc gtttgaccaa cgataccgag acgattagtg
    41221 atatgttttc tgggatttta tccagcttta tctcagcagt ttttatcttt ctgacaaccc
    41281 tttataccat gttggtgctg gattttcgtt tgacggcttt agtcttgctc tttctccctt
    41341 tgattttcct tttggtcaat ctctatcgaa aaaagtcagt gaaaatcatc gagaaaacca
    41401 gaagtctctt gtcagatatc aatagtaagc tggcagagaa tatcgaggga atcaggatta
    41461 ttcaggcttt taatcaagag aagcgcctgc aggcagaatt tgatgaaatc aaccaagaac
    41521 acttggtcta cgccaaccgt tctgtagcct tggatgccct ctttttgaga cctgccatga
    41581 gtttgctgaa acttctaggc tatgcagtct tgatggccta ctttggctac cgtggttttt
    41641 ctatcgggat aacggtcggg accatgtatg cctttatcca gtacatcaac cgcctttttg
    41701 accccttgat tgaggtgacg caaaactttt caactctgca aacggctatg gtttctgcag
    41761 gtcgtgtctt tgccctgata gacgagagga cctatgaacc tcttcaagaa aatgggcaag
    41821 ccaaagtcca agaaggcaat atccgttttg aacatgtgtg tttctcatat gacggtaaac
    41881 atccgattct ggatgacatt tctttctctg ttaataaggg tgaaaccatt gcctttgtag
    41941 gtcatacagg ttcagggaaa tcgtctatta tcaatgtcct catgcgcttt tatgaattcc
    42001 agtcagggag agttctcttg gatgatgtgg atatcaggga tttcagtcaa gaagagctga
    42061 gaaaaaacat cggtttggtc ttgcaggaac ccttcctcta tcatggaact attaagtcca
    42121 atatcgccat gtaccaagaa accagtgatg agcaggttca ggctgcggca gcctttgtgg
    42181 atgcagattc ctttattcaa gaacttcctc aggggtacga ctcccctgtt tccgagcgtg
    42241 gtttgagctt ctctactggg caacgccagc ttcttgcctt tgctagaaca gtcgccagcc
    42301 agcctaaaat cctgattttg gatgaagcga cagccaatat tgactctgaa acagaaagct
    42361 tggttcaagc ttctctggcg aagatgagac agggccgaac aactattgct atcgctcacc
    42421 gcctttctac tattcaagat gccaactgca tctatgtctt ggataaggga cgcattatcg
    42481 agagtggaac ccatgaggaa ctcttggctc tgggaggaac ctatcacaag atgtatagtt
    42541 tgcaggcagg ggccatggcc gatactcttt gaaaatctct ttaaaccatg tcagctttat
    42601 ctgcaatctc aaagctgtac tttgattttc attgagtact agaaggaaat ccttcaaatt
    42661 acagatttct ttcaccgcct tttccatttt gtggtataat gaaaaatgtt gacaaatagt
    42721 ataataaaaa caaaggagaa cagcatgctg aaatgggaag acttgcctgt ggaaatgaaa
    42781 tcaagcgagg ttgagtctta ctaccagctt gtctctaaaa ggaagggttc gctgattttc
    42841 aagcgttgct tggactgggt tttggccttg gtcttactgg ttctaacttc tcccatcttt
    42901 ctcatcttga gcatttggat caagttggat agcaaggggc cagtgattta caagcaagag
    42961 cgtgtgaccc agtacaactg tcggttcaag atttggaagt tccgtaccat ggtgacggat
    43021 gcggataaaa aaggaagtct ggtgacttct gctaacgata gccgtattac caaggttgga
    43081 aatttcatcc gacgtgtccg tttggacgaa ctgcctcagt tggtcaatgt ccttaaaggt
    43141 gagatgtcct ttgtcggtac acgacctgaa gtgccacgtt atacagagca gtatagccct
    43201 gaaatgatgg caaccttgct cttgcaagca ggaattacct ctccagccag catcaactac
    43261 aaggatgagg acaccatcat cagtcaaatg acggagaaag gtctgtcagt tgatcaggcc
    43321 tatgtggagc atgttcttcc tgaaaagatg cgctataacc tcgcctatct ccgagagttt
    43381 agtttctttg gggacatcaa aatcatgttt caaaccgtgt ttgaggtact aaaataaagt
    43441 agtcataaga aaatgagtac agataaaagg agcaaatcaa tgccaaatta caatattcca
    43501 ttttcaccgc ctgatatcac agaagcagaa attgctgaag tagcggatac cctgcgttct
    43561 ggttggatca caacaggtcc taaaacaaaa gaactggagc gccgcttgtc tctttacaca
    43621 cagacaccta agactgtttg tctcaactct gcgacagccg ctctggagtt gattttacgc
    43681 gttttggaag tgggacctgg tgatgaagtc atcgttccag ccatgaccta tacggcttca
    43741 tgtagtgtca ttacgcacgt gggagcaacc cctgtcatgg tggatatcca agcagatacg
    43801 tttgagatgg actatgacct gcttgagcaa gctatcactg agaaaactaa ggtgattatc
    43861 ccagtagagc tcgcagggat tgtttgcgat tatgaccgtt tgttccaagt cgtggagaaa
    43921 aaacgtgact tctttaccgc ttcaagcaag tggcaaaagg cctttaaccg tattgtcatt
    43981 gtctctgata gtgcccacgc tttgggatct acttataaag gacaaccttc tggttctatc
    44041 gctgacttta cttccttctc attccatgcc gttaagaact ttacaacggc agaaggtgga
    44101 agtgcgactt ggaaagccaa tccagtgatt gatgacgaag agatgtacaa ggaattccaa
    44161 atcctttccc ttcacgggca aactaaggat gctcttgcca agatgcaatt ggggtcatgg
    44221 gaatacgata tcgttacacc agcctataag tgcaacatga ccgatatcat ggcttcactt
    44281 ggtttggtac aattggaccg ctatccaagt ttgttgcaac gccgtaagga cattgtggac
    44341 cgctatgata gtggttttgc aggttctcgc atccatcctt tggcacacaa gactgaaact
    44401 gtcgaatctt cacgccacct ctacatcacc cgtgtagaag gagcaagcct agaagaacgc
    44461 aacctcatca tccaagaatt ggctaaagca ggaattgcaa gtaatgttca ctacaaaccg
    44521 cttcctctct tgacagccta taagaatctt ggatttgata tgacgaacta tcctaaggcc
    44581 tatgccttct ttgagaatga aattaccctc cctcttcata ctaaattaag cgatgaagaa
    44641 gtagactata tcattgagac tttcaaaaca gtttctgaaa aagtgctaac tttatcaaaa
    44701 aaatgacaaa ctacagtcaa gcgaaagtga tcctgtccct aaaaagtcta attgagtgta
    44761 aaaactgttg ttttcaattg ataatagttt acacctgtag ttgaggcctc tttctcctca
    44821 gagagagaat ttttatagga ttttcctttc ttgtgggagt cccgtggttt gaaataagat
    44881 gtgagcaatt tagtgtagca tttagaatcc ttactagaca tcatttagaa aatctagtgt
    44941 cttgttctag ttttcaattc accctatttt ttgaaagacg tgagtttcca tgagtgagat
    45001 tgtggaaact cgcgtctttt tttgttttca gaatattgtt caaaattttg tgcctgtctt
    45061 tcatgttcta gtcattcttt tgcatgatag aatttatagc atgttgatat tataataata
    45121 caaatattct atatgtttag tgatgcttgc tatacatcat tagatctcct gcgagacaat
    45181 ctataaaaca cttgtctacg attacctata tgccctattc cagtatttta gaagcactgc
    45241 atctattttt atcgaggtta aatctagctt ttatagaagg tctatttaag aaatatattg
    45301 tagtgtttta gtttcaatcc gccatatgag cgatattcag gtaaatatcc ctggcgaatg
    45361 cttgtatgac aaggtatttg ttctttcatt tataatttac aacatatcaa caaatttaaa
    45421 tatagtaaat gggatatttt atattcaagc taagaaagat agcatcactt ttgaatggaa
    45481 ggctaaagag caaactagga agttggccat agatagctca aaaccctgct ttgaggttgt
    45541 agatatagta aaatgaaata agaataggac aaattgatcg ggacagtcaa atcgatttct
    45601 aacaatgttt tagaagtaga ggtgtactat tttagtttca gtctactata gaactgacca
    45661 agtcagtaac ctagacttag ggcaaggcgg cactgaccta gtttgaagag atttccgaag
    45721 agtataaatt ttaatatttt cttgtgttat tccttgacaa ttcaatttgg aaaatatatg
    45781 ataaagataa tgacagcggt gtcattctat ctattttaag aaaagtaata atcaattgtt
    45841 aaaaatagta aaaaaattgg aggttctgat gaaatatttt gttcctaatg aggtattcag
    45901 tattcgtaaa ttaaaggtgg ggacttgctc ggtactattg gcaatttcaa ttttgggaag
    45961 ccaaggtatt ttatcggatg aagttgttac tagttcttca ccgatggcta caaaagagtc
    46021 ttctaatgca attactaatg atttagataa ttcaccaact gttaatcaga atcgttctgc
    46081 tgaaatgatt gcctctaatt caaccactaa tggtttagat aattcgttaa gtgttaatag
    46141 tatcagctct aatggtacta ttcgttccaa ttcacaatta gacaacagaa cagttgaatc
    46201 tacagtaaca tctactaatg aaaataagag ttataaggaa gatgttataa gtgacagaat
    46261 tatcaaaaaa gaatttgaag atactgcttt aagtgtaaaa gattatggtg cggtaggtga
    46321 tgggattcat gatgatcgac aagcaattca agatgcaata gatgctgcag ctcaagggct
    46381 aggtggagga aatgtatatt ttcctgaagg aacttattta gtaaaagaaa ttgttttttt
    46441 aaaaagtcat acacacttag aattgaatga gaaagctaca attctaaatg gtataaatat
    46501 taagaatcac ccttccattg tttttatgac aggtttattt acggatgatg gtgcgcaagt
    46561 agaatggggc ccaacagaag atattagtta ttctggtggt acgattgata tgaacggtgc
    46621 tttgaatgaa gaaggaacta aagcaaaaaa tctaccactt ataaattctt caggtgcatt
    46681 tgctattggg aattcaaata acgtaactat aaaaaatgta acattcaagg atagttatca
    46741 agggcatgct attcaaattg caggttcgaa aaatgtatta gttgataatt ctcgttttct
    46801 tgggcaagcc ttacccaaaa cgatgaagga tgggcaaatc ataagtaagg agagcattca
    46861 gattgaacca ttaactagaa aaggttttcc ttatgccttg aatgatgatg ggaaaaaatc
    46921 tgaaaatgtg actattcaaa attcctattt tggcaaaagt gataaatctg gggaattagt
    46981 aacagcaatt ggcacacact atcaaacatt gtcgacacag aacccctcta atattaaaat
    47041 tttaaataat cattttgata acatgatgta tgcaggtgta cgttttacag gattcactga
    47101 tgtattaatc aaaggaaatc gctttgataa gaaagttaaa ggagagagtg tacattatcg
    47161 agaaagcgga gcagctttag taaatgctta tagctataaa aacactaaag acctattaga
    47221 tttaaataaa caggtggtta tcgccgaaaa tatatttaat attgccgatc ctaaaacaaa
    47281 agcgatacga gttgcaaaag atagtgcaga atatttagga aaagtatcag atattactgt
    47341 aacaaaaaat gtaattaata ataattctaa ggaaacagaa caaccaaata ttgaattatt
    47401 acgagttagt gataatttag tagtctcaga gaatagtata ttcgggggta aagaaggaat
    47461 tgttattgag gattcaaagg gtaaaataac cgttttaaat aaccaatttt ataatttatc
    47521 cggtaagtat atatcattca tcaaatctaa tgcaaatggg aaagaacctg ttatacgtga
    47581 tagcgatggt aatttcaata ttgtaacgga gaatgggctt tacaatattg taacaaataa
    47641 tttaagtgat aaaaacgaaa aagaaaaaaa caaagaggaa aaacaatcta attcaaataa
    47701 tgtaattgat agtaaccaga agaacggaga gtttaactca agtaaagata atagacaaat
    47761 gaatgacaag atcgacaata aacaagataa taagacagaa gaagtaaact ataaaatagt
    47821 tggagatggc agagaaactg aaaatcatat taataaatct aaagaaatag tagatgtaaa
    47881 acaaaaatta ccaaagactg gttcgaacaa gattatggaa ctattcttaa cagtgacagg
    47941 aattggttta cttttgacac taaaagggtt gaagtattat ggtaaagata aataaaattt
    48001 gttcgataca aggaagttcc gtagaaaatg aggatattgt aggttcacaa aatcagtatt
    48061 tttggattat tggtggagct acagatttat ataattctaa agaggagata ggttattcag
    48121 tctcagaagt tgtacatatt ttatcagaaa gtttgtcggt taattgtaaa gaatcaaaaa
    48181 ctcttaaaca aatatttgaa actgctttac tcgaggttaa agatgaaatc ggtttaaact
    48241 catatgaatt aacagagtat agtaaaatga aataataata ggacaaatca atcaggacag
    48301 tcaaatcgat ttctaacaat gttttagaag tagaggtgta ctattctagt ttcaatatac
    48361 tatattatcg cttaccaata tttgctaaac tttcagaaaa aaagttggag tatatgatgc
    48421 taggtgactg cgtcatgtta gtaaacgaaa tggaaataac tgatcataga gtagataact
    48481 tatttgaaaa agggaaaaat gagataaaag attcaagtag tagatttagc aataggacat
    48541 ataaaagctt tagaaaaagt atctgaaaaa acagatgttt atatctataa cctaggctcg
    48601 ggagaaggca ctagtgtatt acaacttgta aatacatttg aaagtgttaa taagatccct
    48661 attccttata aaatagttcc aagacgttca ggagacgttg caacttatta tgcaaatgca
    48721 gacaaagcat ataaggaatt aaattggagg acaacaaaat cgattgaaga catgtgtaga
    48781 gatacatgga attggcaatc aaaaaatccc aatggctata attgatgata ctgtctatat
    48841 gagtgctgta ttttggaaaa attacttaac cttttaatga aagataaatt aaaaaaaatg
    48901 tttgacagcg cttgacaaag gaaacggttt cattgtataa tgtaaacaca atgacaccga
    48961 tgtcaaatat aaaaaagaag gtctttatat gaaaaactta acaaaaatta agttcaaaga
    49021 aaatggggaa tttaatcatt tccctgggaa tacagttgta gcaaatcttt atactaaaca
    49081 agatttgatg gaagttgttg atattattca atcacgttat agagaattac catttatcga
    49141 taagtttact ttaactccaa ggaattctat tcacatgact gtaattgaat tgttgtgcca
    49201 tgaaaatcgt gaaacggagt tttggagcag taatcttcct ctagatacac ctttacagga
    49261 aatacatgat tactttgcta aacaacttga aatttttcca ttgttggatg aagaaattca
    49321 tatgcgtata actgaaatgg gaaaacaaaa catactagtt gaacctgcag atgaagcttc
    49381 tgcaaagaga ttagaagaaa ttcgtactta tgtctcagaa aaagcaggtg tttgtttccc
    49441 taatcatgat agatatcaat tccatatttc aattgggtat cttcggattc ctctaaccga
    49501 agaggaggaa gaagagttta ctaaagtcag agcagaatta actgaaattt tattagagaa
    49561 gattccaact attactgtaa accgtattga ctatactgta tttgaagata tgagacaatt
    49621 tgttccatat cacgaaaaat ttaaataaaa taataaaaaa ggagaactta tcatgaaaaa
    49681 aatgaaagtt tggtctactg tacttgcaac gggagttgct cttactacac ttgctgcttg
    49741 ctctggaggt tcaaattcta cgactgcttc ttcatctgaa gaaaaagctg ataaaagtca
    49801 agaattagtt atctattcga actcagtctc aaatggtcgt ggtgattggt taactgctaa
    49861 agcaaaagaa gctggtttta atataaaaat ggttgatatc gctggcgctc aattagcaga
    49921 ccgtgttatt gctgagaaga ataatgcagt tgcagatatg gtatttggaa ttggtgctgt
    49981 tgactcaaat aaaattagag atcaaaaatt actagtacag tacaagccta aatggttaga
    50041 taaaattgat caatctttat cagataaaga taattattat aatcctgtga ttgttcaacc
    50101 attagtttta attggggcgc ctgatgtaaa agaaatgcct aaagattgga ctgaattagg
    50161 tagtaagtat aaaggtaaat attcaattta tggtcttcaa ggtggtacag gacgggcaat
    50221 tctagcaagt atcttagttc gttaccttga tgaaaaagga gatttaggcg tatcagaaaa
    50281 aggatgggaa gttgcaaaag aatactttgc aaatgcctat actcttcaaa aaggtgaaag
    50341 ctcagttgtt aaagcgttag ataaagaaag cccaattcaa tacggtatga tctggggttc
    50401 tggatcgtta attggacaaa aagaacaaaa tgttgaattc aaagttatga ctcctgagat
    50461 tggtgtacca tttgtaactg aacaaactat ggttttaagc actagtaaaa aacaagcgtt
    50521 agctaaagaa tttattgatt ggtttggtca atcagaaatt caagtagaat atagtaaaaa
    50581 atttggatct attcctgcaa ataaagatgc cctaaaagag ttacctgaag atacgaaaaa
    50641 atttgttgat caagtgaaac cacaaaatat tgactgggaa gctgttggaa agcatttgga
    50701 tgaatgggta gaaaaagctg aattagaata cgtacaataa gaaataagag ttatttttta
    50761 tgtccaagtc tctctattat ttctaaattt aaggaagaaa taaagagagg cttttggttt
    50821 agtaatagag ggagttagtg agatgattaa atttgataat attcaaatta aatatggtga
    50881 ttttgttgca attgataatc tgaatttaga tatacatgaa ggggaattct ttacatttct
    50941 tgggccttca ggatgtggta aatcaactac tttgagagca ttggtaggtt ttttagatcc
    51001 atcatcagga agtattgaag ttaatggaac agatgtcact catttggaac ctgaaaagcg
    51061 tggaattggt attgtatttc aatcttatgc gctatttcca actatgactg tttttgataa
    51121 tattgcattt ggtttaaaag ttaagaaggt agctccagat gttattaaag ctaaagtatc
    51181 agcagtggca gcaaaaatta agatctctga tcaacagtta cagcgtaatg tatcagaatt
    51241 atctgggggt caacaacaaa gggtagcatt ggctcgtgct ctggttcttg aacctaaaat
    51301 tctttgtcta gatgaaccat tgtcaaacct tgacgcaaaa ttacgtgtag atttgagaaa
    51361 agagttgaaa agacttcaaa aagagttagg tattactact ttatatgtta ctcatgatca
    51421 agaggaagcc ttgactttat ctgatagaat tgcagtcttt aacaatggat acatcgaaca
    51481 ggtcggtaca ccagtagaga tttatcataa ttctcaaact gaatttgtat gtgattttat
    51541 tggagatatt aatgttttga ccgatgaaac agtccacgaa gtattattga aaaatacaag
    51601 cgttttctta gaggataaaa aaggatacat tcgattagag aaagttcgat tcaatcgtga
    51661 aactgaacaa gattttattc taaaagggac aattattgat gttgagtttt ctggagttac
    51721 aattcactat acaataaaag tttctgaaag tcagattctt aatgtaacaa gtattgatag
    51781 tcaggctgct attagatctg tcggagaaag tgtggaatta tttatcacac catcagacgt
    51841 tctgcaattt taaggaggtg cagtatgcgt cataaattaa atttaaaaga ttggcttatt
    51901 cgtttaggat taatctggtt cttagtaaca tttattattt atccaaactt tgatctagta
    51961 gtgaatgtat ttgtaaaagg aggagaattt tcccttgatg ctgtacatcg tgttctaaaa
    52021 tctcagaggg cacttcagag tattatgaac agttttaagt tagcattttc actcattatt
    52081 acagttaatg tcgtaggtat tctttgtgtt ctatttacag agtactttga tattaaaggt
    52141 gctaaaattt taaaattagg ttatatgacc tctttaattt atggaggagt ggttttagcg
    52201 actggatata aatttgtcta tggtccttat ggattgatta caaaattttt acaaaatgtt
    52261 atcccttctt tagactctaa ctggtttatt gggtatggtg cagtcttatt cattatgaca
    52321 ttttcaggaa ctgctaatca tacattgttt ttaacaaata caattcgaag cgttgactat
    52381 cacactattg aggctgctcg aaatatggga gcaaaaccat ttactgtttt ccgaaaagta
    52441 gtgttaccaa ccttaattcc aactctattt gcacttacta ttatggtttt tcttagtggt
    52501 ttatctgcag tagcagcacc catgattgtt ggtggtaaag aatttcaaac tataaatcca
    52561 atgattatta catttgcagg gatggggaat tctcgtgatt tagctgcctt acttgcaatt
    52621 attttaggta ttgcaactac aattttgctt actatcatga ataagataga aaaaggtgga
    52681 aattatattt ctatctctaa gactaaagcg cctcttaaaa aacaaaaaat tgcgtctaag
    52741 ccttggaata tcattgctca cattgtagca tatggattgt tcacagtttt catgcttcca
    52801 ctaattttta tagtattata ctcatttaca gatccagttg caattcaaac aggtaactta
    52861 acattatcaa actttacttt agaaaattat cgcttattct ttagtaatag tgcggcattc
    52921 tctccattct tggtcagctt tatttattct attattgctg cgacaacagc aacaattctc
    52981 gcagttgtat ttgctcgtgt tgtcagaaaa cataaatctc gttttgattt cttatttgaa
    53041 tatggtgctc tacttccttg gttactacca agtacacttt tagcagtaag tttattattt
    53101 acttttaatc agccacaatt tcttgtcttg aatcagattt tggtaggtag tttggtaatt
    53161 ctacttattg catatatagt tgtaaaaatc ccattttctt atagaatggt ccgtgctatt
    53221 ttatttagtg ttgatgatga gatggaagat gcagcaagaa gtatgggtgc ttcacctttt
    53281 tatactatga tgaaggttat cattccattt attttaccgg ttgttctctc tgttattgct
    53341 ttaaacttta actctttatt aactgacttc gacttatctg tattccttta ccatccccta
    53401 gctcaaccat taggtattac gattcgatct gcaggtgatg aaacagcaac atctaatgca
    53461 caagctctag tatttgttta tacaattgtt ctgatgatta tttctggaac ggtattatac
    53521 ttcacacaaa gaccggggcg taaagtaagg aaataatcat gacagccact agtcttgggt
    53581 tatcaaatat tgaaatagtt gtcaggattg ttttatcagt agtcattggt agtataattg
    53641 gtttagagag agggagcaaa tcccagcctg caggcatccg aacttatagt attgtttgtc
    53701 tagctgcatg tttgattatg atgacgaatg aatacgtatc ttataaattt gggacaggag
    53761 atcctacacg attaggagct caagttatat caggtgtggg ttttctaggc gctggaacga
    53821 ttcttattac agataaaaag aaaattacag gtctgacaac tgcagcaggc atttgggctt
    53881 cggcaggaat tggattagct attggagtag gtttttatga gggagctctt ttagtagcca
    53941 tttctgtttg gggtgtgata tccatgttcc aaccactaaa aaaatatctg caaaatcgtt
    54001 ctaaaatgat tgaattgtat atagtggtta aatctacaga agcctataat cgtgtattgg
    54061 tttattgtgc agaaaatggt atcagaatga ccgattcaag aacagcgttt ggagatgtta
    54121 attctgacag aattgaatac tttgatgttc cggacaaaaa aatagcgtca tttattactc
    54181 tggaattatc aggtagattt gaacatcttc gactgatgga agaaattgct aatattgtag
    54241 gtgttattta tgtcgaagaa attagctgaa atttagtaaa caaagggaca gatgtttttg
    54301 tccttttgtt ttttagatgt tttaatcatc taatttttga gtagattttt gctcagaggt
    54361 ttttatgaaa gattataaaa tcaattttga tttaggtaaa ataga
//
LOCUS       DAVLXH010000008        54376 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00028199
            SAMN33607166-rid17955573.denovo.008, whole genome shotgun sequence.
ACCESSION   DAVLXH010000008 DAVLXH010000000
VERSION     DAVLXH010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607166
            Sequence Read Archive: SRR23725544
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 54376)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 54376)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721421.1
            Genome Coverage       :: 115x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:42:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,210
            CDSs (total)                      :: 2,161
            Genes (coding)                    :: 2,023
            CDSs (with protein)               :: 2,023
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 73 of 138
            Pseudo Genes (incomplete)         :: 60 of 138
            Pseudo Genes (internal stop)      :: 40 of 138
            Pseudo Genes (multiple problems)  :: 31 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..54376
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607166-rid17955573.denovo.008"
                     /strain="AUSMDU00028199"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1349"
     gene            402..614
                     /locus_tag="VYO11_000541"
     CDS             402..614
                     /locus_tag="VYO11_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1595143.1"
                     /translation="MSFYGLFYNGIAITPNTYLSAWFVNFIAALPLNFLIVEPIARFI
                     LSSFQKPFTGEEVEDFQDDDEIPTII"
     gene            697..1500
                     /locus_tag="VYO11_000542"
     CDS             697..1500
                     /locus_tag="VYO11_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HEV1595144.1"
                     /translation="MKKLATLLLLSTVALAGCSSVQRSLRGDDYVDSSLAAEESSKVA
                     AQSAKELNDALTNENANFPQLSKEVAEDEAEVILHTSQGDIRIKLFPKLAPLAVENFL
                     THAKEGYYNGITFHRVIDGFMVQTGDPKGDGTGGQSIWHDKDKTKDKGTGFKNEITPY
                     LYNIRGALAMANTGQPNTNGSQFFINQNSTDTSSKLPTSKYPQKIIEAYKEGGNPSLD
                     GKHPVFGQVIGGMDVVDKIAKAEKDEKDKPTTAITIDSIEVVKDYDFKS"
     gene            complement(1557..3098)
                     /locus_tag="VYO11_000543"
     CDS             complement(1557..3098)
                     /locus_tag="VYO11_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002918612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEV1595145.1"
                     /translation="MSILEVKNLSHGFGDRAIFEDVSFRLLKGEHIGLVGANGEGKST
                     FMSIVTGKMLPDEGKVEWSKYVTAGYLDQHSVLAERQSVRDVLRTAFDELFKAEARIN
                     DLYMKMAEDGADVDALMEEVGELQDRLESRDFYTLDAKIDEVARALGVMDFGMDTDVT
                     SLSGGQRTKVLLAKLLLEKPDILLLDEPTNYLDAEHIDWLKRYLQNYENAFVLISHDI
                     PFLNDVINIVYHVENQQLTRYSGDYYQFQEVYAMKKSQLEAAYERQQKEIADLKDFVA
                     RNKARVATRNMAMSRQKKLDKMDIIELQSEKPKPSFDFKPARTPGRFIFQAKNLQIGY
                     DRPLTKPLNLTFERNQKVAIIGANGIGKTTLLKSLLGIISPIAGEVERGDYLELGYFE
                     QEVEGGNRQTPLEAVWNAFPALNQAEVRAALARCGLTTKHIESQIQVLSGGEQAKVRF
                     CLLMNRENNVLVLDEPTNHLDVDAKDELKRALKEYRGSILMVCHELDFYEGWIDQIWD
                     FNNLT"
     gene            complement(3100..3582)
                     /locus_tag="VYO11_000544"
     CDS             complement(3100..3582)
                     /locus_tag="VYO11_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000976721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HEV1595146.1"
                     /translation="MMKKTYNHILVWGVIFYSICIVCFCFTPQEQSTVGVGTPGIQHL
                     GRLVFLLTPFNSLWKLGEVSDIGQLCWIFLQNILNVFLFFPLIFQLLYLFPNLRKTKK
                     VLLFSFLVSLGIECTQLILDFFFDFNRVFEIDDLWTNTLGGYLAWLLYKRLHKNKIRN
                     "
     gene            complement(3582..4667)
                     /gene="rlmN"
                     /locus_tag="VYO11_000545"
     CDS             complement(3582..4667)
                     /gene="rlmN"
                     /locus_tag="VYO11_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000804770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HEV1595147.1"
                     /translation="MKPSIHSLAHQTMQEWVLEQGEKKFRADQIWEWLYRKRVQSFEE
                     MTNLSKDLIAKLNDQFVVNPLKQRIVQESADGTVKYLFELPDGMLIETVLMRQHYGLS
                     VCVTTQVGCNIGCTFCASGLIKKQRDLNNGEIVAQIMLVQKYFAERGQDERVSHIVVM
                     GIGEPFDNYNNVLNFFRTINDDKGMAIGARHITVSTSGLAHKIRDFADEGVQVNLAVS
                     LHAPNNELRSSIMKINRAFPIEKLFAAIEYYIETTNRGVTFEYIMLNEVNDGVEQALE
                     LTELLKNIKKLSYVNLIPYNPVSEHDQYSRSPKERVLAFYDTLKKKGVNCVVRQEHGT
                     DIDAACGQLRSNTMKRDRQKAVAAVNP"
     gene            complement(4688..5218)
                     /locus_tag="VYO11_000546"
     CDS             complement(4688..5218)
                     /locus_tag="VYO11_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HEV1595148.1"
                     /translation="MRKEIAPELYNYNKFPGPEFHLHGDKVETEGIAFSLVENIKDAF
                     DVTTFNQRFSEVLTKFDYIVGDWSNEQLRLRGFYKDDRTEEKLEKISRLQDYLLEYCS
                     YGCSYFVLENEAPKRASFDKKMRKTEEETPSRKGKKPTQTKRKSNADKKNRRRQKDQH
                     SQKEDKGQRHFVIRQK"
     gene            complement(5374..5979)
                     /locus_tag="VYO11_000547"
     CDS             complement(5374..5979)
                     /locus_tag="VYO11_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HEV1595149.1"
                     /translation="MAIILPELPYAYDALEPYIDAETMHLHHDKHHQTYVNNANAALE
                     KHPEIGEDLEALLADVESIPADIRQALINNGGGHLNHALFWELMTPEKTAPSAELAAA
                     IDATFGSFEEFQAAFTAAATTRFGSGWAWLVVNKEGKLEVTSTANQDTPISEGKKPIL
                     GLDVWEHAYYVKYRNVRPDYIKAFFSVINWNKVDELYAAAK"
     gene            complement(6152..7189)
                     /locus_tag="VYO11_000548"
     CDS             complement(6152..7189)
                     /locus_tag="VYO11_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HEV1595150.1"
                     /translation="MLAIEESQKLTLSNLPSLSLFTGTDQGQFEVMKSQVLKQIGYDS
                     ADLNFAYFDMKEVVYKDVELELVSLPFFADEKIVILDYFMDITTAKKRFLTDDELKSF
                     EEYLDNSSPTTKLIIFAEGKLDSKRRLVKLLKRDAKVFDAVEVKEQELRQYFQKWSQK
                     QGLQFTNHSFENLLIKSGFQFSEIQKNLLFLQSYKANSVIEEEDIVNAIPKTLQDNIF
                     DLTQFILTKKMDQARDLVRDLTLQGEDEIKLIAVMLGQFRTFTQVKILAESGQTESQI
                     ASSLGSYLGRNPNPYQIKFALRDSRGLSLSFLKQAISYLIETDYQIKTGLYEKGFLFE
                     KALLQIASQVN"
     gene            complement(7223..8158)
                     /locus_tag="VYO11_000549"
     CDS             complement(7223..8158)
                     /locus_tag="VYO11_000549"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HEV1595151.1"
                     /translation="MVSTKTQIAGFEFDNCLMNAAGVACMTIEELEEVKNSAAGTFVT
                     KTATLDFRQGNPEPRYQDVPLGSINSMGLPNNGLDYYLDYLLDLQEKESNRTFFLSLV
                     GMSPEETHTILKKVQESDFRGLTELNLSCPNVPGKPQIAYDFETTDRILAEVFAYFTK
                     PLGIKLPPYFDIVHFDQAAAIFNKYPLKFVNCVNSIGNGLYIEDESVVIRPKNGFGGI
                     GGEYIKPTALANVHAFYQRLNPQIQIIGTGGVLTGRDAFEHILCGASMVQVGTTLHKE
                     GVSAFDRITNELKAIMAEKGYESLEDFRGKLRYID"
     gene            complement(8711..9901)
                     /locus_tag="VYO11_000550"
     CDS             complement(8711..9901)
                     /locus_tag="VYO11_000550"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HEV1595152.1"
                     /translation="MSERKLFTSESVSEGHPDKIADQISDAILDAILAKDPEAHVAAE
                     TAVYTGSVHVFGEISTNAYVDINRVVRDTIAEIGYTNTEYGFSAETVGVHPSLVEQSP
                     DIAQGVNEALEVRGNADQDPLDLIGAGDQGLMFGFAVDETEELMPLPIALSHKLVRRL
                     AELRKSGEISYLRPDAKSQVTVEYDENDRPVRVDTVVISTQHDPEATNEQIHQDVIDK
                     VIKEVIPSSYLDDKTKFFINPTGRFVIGGPQGDSGLTGRKIIVDTYGGYSRHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAAGLAKKAEVQLAYAIGVAQPVSVRIDTFGTGTVA
                     ESQLEKAARQIFDLRPAGIIQMLDLKRPIYRQTSAYGHMGRTDIDLPWERLDKVDALK
                     EAVK"
     gene            complement(10116..11459)
                     /locus_tag="VYO11_000551"
     CDS             complement(10116..11459)
                     /locus_tag="VYO11_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEV1595153.1"
                     /translation="MSFTKFQFKNYIREALKELKFTTPTEVQDKLIPIVLAGRDLVGE
                     SKTGSGKTHTFLLPIFQQLDEASDSVQAVITAPSRELATQIYQVARQISAHSDVEVRV
                     VNYVGGTDKARQIEKLESNQPHIVIGTPGRIYDLVKSGDLAIHKAKTFVVDEADMTLD
                     MGFLETVDKIAGSLPKDLQFMVFSATIPQKLQPFLKKYLSNPVMEKIKTKTVISDTID
                     NWLISTKGHDKNAQIYQLTQLMQPYLAMIFVNTKTRADELHSYLTAQGLKVAKIHGDI
                     APRERKRIMNQVQNLDFEYIVATDLAARGIDIEGVSHVINDAIPQDLSFFVHRVGRTG
                     RNGLPGTAITLYQPSDDSDIRELEKLGIKFSPKMVKDGEFQDTYDRDRRANREKKQDK
                     LDIEMIGLVKKKKKKVKPGYKKKIQWAVDEKRRKTKRAENRARGRAERKAKRQTF"
     gene            complement(11599..12414)
                     /locus_tag="VYO11_000552"
     CDS             complement(11599..12414)
                     /locus_tag="VYO11_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HEV1595154.1"
                     /translation="MKFLTLNTHSWMEKEAEEKFQILLEDILEKDYDLICFQEINQEM
                     TSSEVEVNDLYQALPAAEPIHQDHYVRLLVEKLSEQGKNYYWTWAYNHIGYDRYHEGV
                     AILSKTPIEAREILVSDVDDPTDYHTRRVALAETVVDGKELAVASVHLSWWDKGFQEE
                     WARFEVVLKKLNKPLLLAGDFNNPAGQEGYQAILASPLGLQDAFEVAQEKSGSYTVPP
                     EIDGWKGNTEPLRIDYVFTTKELAVENLHVVFDGNKSPQVSDHYGLNAMLNWK"
     gene            complement(12466..14646)
                     /locus_tag="VYO11_000553"
     CDS             complement(12466..14646)
                     /locus_tag="VYO11_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000974069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEV1595155.1"
                     /translation="MMKDTFKNVLSFEFWQKFGKALMVVIAVMPAAGLMISIGKSIVM
                     INPTFTPLVITGGILEQIGWGVIGNLHILFALAIGGSWAKERAGGAFAAGLAFILINR
                     ITGTIFGVSGDMLKNPDAMVTTFFGGSIKVADYFISVLEAPALNMGVFVGIISGFVGA
                     TAYNKYYNFRKLPDALSFFNGKRFVPFVVILRSAIAAILLAAFWPVVQTGINNFGIWI
                     ANSQETAPILAPFLYGTLERLLLPFGLHHMLTIPMNYTALGGTYDILTGAAKGTQVFG
                     QDPLWLAWVTDLVNLKGTDASQYQHLLDTVHPARFKVGQMIGSFGILMGVIVAIYRNV
                     DADKKHKYKGMMIATALATFLTGVTEPIEYMFMFIATPMYLVYSLVQGAAFAMADVVN
                     LRMHSFGSIEFLTRTPIAISAGIGMDIVNFVWVTVLFAVIMYFIANFMIQKFNYATPG
                     RNGNYETAEGSEETSSEVKVAAGSQAVNIINLLGGRVNIVDVDACMTRLRVTVKDADK
                     VGNAEQWKAEGAMGLVMKGQGVQAIYGPKADILKSDIQDILDSGEIIPETLPSQMTEV
                     QQNTVHFKDLTEEVYSVADGQVVALEQVKDPVFAQKMMGDGFAVEPANGNIVSPVSGT
                     VSSIFPTKHAFGIVTEAGLEVLVHIGLDTVSLEGKPFTVHVAEGQKVAAGDLLVTADL
                     NAIRAAGRETSTVVVFTNGDAIKSVKLEKTGSLAAKTAVAKVEL"
     gene            15043..15996
                     /locus_tag="VYO11_000554"
     CDS             15043..15996
                     /locus_tag="VYO11_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30-like element ISSpn8 family transposase"
                     /protein_id="HEV1595156.1"
                     /translation="MQEHYTPKGKHLTIDNRRLIERWKNENKSNREIAGLLGKAPQTI
                     HNEVKRGTTLQQVRKGLYKKVYSADYAQTVYQFNRKRSVKKLILTKEIREKILHYHKQ
                     KFSPEMMVNKKQVKVGISTIYYWFHNGHLGLTKADMLYPRKRKGVKKQASPNFKPAGK
                     SIEERPDVINLRLENGHYEIDTVLLTKIKNYCLLVLTDRRSRHQIIRLIPNKTAESVN
                     QALTLLLGEHRILSITADNGSEFKRLSEVFPEEHIYYAHAYSSWERGSNENHNRLIRR
                     WLPKGTKKTTPKEVAFIENWINNYPKKCLDYKSPSEFLLGG"
     gene            complement(16177..17103)
                     /locus_tag="VYO11_000555"
     CDS             complement(16177..17103)
                     /locus_tag="VYO11_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1595157.1"
                     /translation="MISRFFRHLFEALKSLKRNGWMTVAAVSSVMITLTLVAIFASVI
                     FNTAKLATDIENNVRVVVYIRKDVEDNSQTIEKEGQTVTNNDYHKVYDSLKNMSTVKS
                     VTFSSKEEQYEKLTEIMGDNWKIFEGDANPLYDAYIVEANAPNDVKTIAEDAKKIEGV
                     SEVQDGGANTERLFKLASFIRVWGLGIAALLIFIAVFLISNTIRITIISRSREIQIMR
                     LVGAKNSYIRGPFLLEGAFIGLLGAIAPSVLVFIVYQIVYQSVNKSLVGQNLSMISPD
                     LFSPLMIALLFVIGVFIGSLGSGISMRRFLKI"
     gene            complement(17096..17788)
                     /gene="ftsE"
                     /locus_tag="VYO11_000556"
     CDS             complement(17096..17788)
                     /gene="ftsE"
                     /locus_tag="VYO11_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HEV1595158.1"
                     /translation="MSIIEMRDVVKKYDNGTTALRGVSVSVQPGEFAYIVGPSGAGKS
                     TFIRSLYREVKIDKGSLSVAGFNLVKIKKKDVPLLRRSVGVVFQDYKLLPKKTVYENI
                     AYAMEVIGENRRNIKKRVMEVLDLVGLKHKVRSFPNELSGGEQQRIAIARAIVNNPKV
                     LIADEPTGNLDPDNSWEIMNLLERINLQGTTILMATHNSQIVNTLRHRVIAIENGRVV
                     RDESKGEYGYDD"
     gene            complement(17806..18901)
                     /gene="prfB"
                     /locus_tag="VYO11_000557"
     CDS             complement(join(17806..18828,18830..18901))
                     /gene="prfB"
                     /locus_tag="VYO11_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511312.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HEV1595159.1"
                     /translation="MDISVIRQKIDANREKLASFRGSLDLEGLEEEIAILENKMTEPD
                     FWNDNIAAQKTSQELNELKNTYNTFHKMEELQDEVEILLDFLAEDESVHDELVAQLAE
                     LDKIMTSYEMTLLLSEPYDHNNAILEIHPGSGGTEAQDWGDMLLRMYTRYGNAKGFKV
                     EVLDYQAGDEAGIKSVTLSFEGPNAYGLLKSEMGVHRLVRISPFDSAKRRHTSFTSVE
                     VMPELDDTIEVEIREDDIKMDTFRSGGAGGQNVNKVSTGVRLTHIPTGIVVQSTVDRT
                     QYGNRDRAMKMLQAKLYQMEQDKKAAEVDSLKGEKKEITWGSQIRSYVFTPYTMVKDH
                     RTSFEVAQVDKVMDGDLDGFIDAYLKWRIS"
     gene            complement(19009..19665)
                     /locus_tag="VYO11_000558"
     CDS             complement(19009..19665)
                     /locus_tag="VYO11_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEV1595160.1"
                     /translation="MAVKDFMTRKVVYISPDTTVSHAADLMREQELHRLPVIENDQLV
                     GLVTEGTIAQASPSKATSLSIYEMNYLLNKTKVKDVMIRDVVTVSGYASLEDATYLML
                     KNKIGILPVVDNHQVYGVITDRDVFQAFLEIAGYGEEGIRVRFVTEDEVGVLGKIVSL
                     IVEENLNISHTVNIPRKDGKVIIEVQIDESIDLPALKEKFEANGIQVEEIARTSAKVL
                     "
     gene            complement(19973..20683)
                     /locus_tag="VYO11_000559"
     CDS             complement(19973..20683)
                     /locus_tag="VYO11_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000062217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1595161.1"
                     /translation="MSMLKVENLSVHYGMIQAVRDVSFEVNEGEVVSLIGANGAGKTT
                     ILRTLSGLVRPSSGKIEFLGQEIQKMPAQKIVAGGLSQVPEGRHVFPGLTVMENLEMG
                     AFLKKNREENQANLKKVFSRFPRLEERKNQDAATLSGGEQQMLAMGRALMSTPKLLLL
                     DEPSMGLAPIFIQEIFDIIQDIQKQGTTVLLIEQNANKALAISDRGYVLETGKIVLSG
                     TGKELASSEEVRKAYLGG"
     gene            complement(20683..21447)
                     /locus_tag="VYO11_000560"
     CDS             complement(20683..21447)
                     /locus_tag="VYO11_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002913097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1595162.1"
                     /translation="MALLEVKQLTKHFGGLTAVGDVTLELNEGELVGLIGPNGAGKTT
                     LFNLLTGVYEPSEGTVTLDGHLLNGKSPYKIASLGLGRTFQNIRLFKDLTVLDNVLIA
                     FGNHHKQHVFTSFLRLPAFYKSEKELKAKALELLKIFDLDGDAETLAKNLSYGQQRRL
                     EIVRALATEPKILFLDEPAAGMNPQETAELTELIRRIKDEFKITIMLIEHDMNLVMEV
                     TERIYVLEYGRLIAQGTPDEIKTNKRVIEAYLGGEA"
     gene            complement(21447..22403)
                     /locus_tag="VYO11_000561"
     CDS             complement(21447..22403)
                     /locus_tag="VYO11_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HEV1595163.1"
                     /translation="MKENLKVNILWLLLLLAGYSLISVLVSVGVLNLFYVQILQQIGI
                     NIILAVGLNLIVGFSGQFSLGHAGFMAIGAYAAAIIGSKSPTYGAFFGAMLVGALLSG
                     AVALLVGIPTLRLKGDYLAVATLGVSEIIRIFIINGGSLTNGAAGILGIPNFTTWQMV
                     YFFVVITTIATLNFLRSPIGRSTLSVREDEIAAESVGVNTTKIKIIAFVFGAITASIA
                     GSLQAGFIGSVVPKDYTFINSINVLIIVVFGGLGSITGAIVSAIVLGILNMLLQDVAS
                     VRMIIYALALVLVMIFRPGGLLGTWELSLSRFFKKSKKEEQN"
     gene            complement(22407..23276)
                     /locus_tag="VYO11_000562"
     CDS             complement(22407..23276)
                     /locus_tag="VYO11_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HEV1595164.1"
                     /translation="MLQQLVNGLILGSVYALLALGYTMVYGIIKLINFAHGDIYMMGA
                     FIGYFLINSFQMNFFVALIVAMLATAILGVVIEFLAYRPLRHSTRIAVLITAIGVSFL
                     LEYGMVYLVGANTRAFPQAIQTVRYDLGPISLTNVQLMILAISLILMILLQVIVQKTK
                     MGKAMRAVSVDSDAAQLMGINVNRTISFTFALGSALAGAAGVLIALYYNSLEPLMGVT
                     PGLKSFVAAVLGGIGIIPGAALGGFVIGLLETFATAFGMSDFRDAIVYGILLLILIVR
                     PAGILGKNVKEKV"
     gene            complement(23544..24704)
                     /locus_tag="VYO11_000563"
     CDS             complement(23544..24704)
                     /locus_tag="VYO11_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEV1595165.1"
                     /translation="MKKKFALSFVALASVALLAACGEVKSGAVNTAGNSVEEKTIKIG
                     FNFEESGSLAAYGTAEQKGAQLAVDEINAAGGIDGKQIEVVDKDNKSETAEAASVTTN
                     LVTQSKVSAVVGPATSGATAAAVANATKAGVPLISPSATQDGLTKGQDYLFIGTFQDS
                     FQGKIISNYVSEKLNAKKVVLYTDNASDYAKGIAKSFRESYKGEIVADETFVAGDTDF
                     QAALTKMKGKDFDAIVVPGYYNEAGKIVNQARGMGIDKPIVGGDGFNGEEFVQQATAE
                     KASNIYFISGFSTTVEVSAKAKAFLDAYRAKYNEEPSTFAALAYDSVHLVANAAKGAK
                     NSGEIKDNLAKTKDFEGVTGQTSFDADHNTVKTAYMMTMNNGKVEAAEVVKP"
     gene            complement(24806..25054)
                     /locus_tag="VYO11_000564"
     CDS             complement(24806..25054)
                     /locus_tag="VYO11_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HEV1595166.1"
                     /translation="MFEKVNRSGLIIYLYYNRDAKKLQDYGDITYHSKKHRYLQLYVP
                     TQEVEQLVGRLSKEKFIKKVRVCHIQELETPFVGNLYR"
     gene            complement(25133..25723)
                     /gene="clpP"
                     /locus_tag="VYO11_000565"
     CDS             complement(25133..25723)
                     /gene="clpP"
                     /locus_tag="VYO11_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease proteolytic subunit
                     ClpP"
                     /protein_id="HEV1595167.1"
                     /translation="MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIA
                     QLLFLDAQDSTKDIYLYVNTPGGSVSAGLAIVDTMNFIKADVQTIVMGMAASMGTVIA
                     SSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRNTLEKILAENSGQ
                     SMEKVHADAERDNWMSAQETLEYGFIDEIMANNSLN"
     gene            complement(25897..26526)
                     /gene="upp"
                     /locus_tag="VYO11_000566"
     CDS             complement(25897..26526)
                     /gene="upp"
                     /locus_tag="VYO11_000566"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002883819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HEV1595168.1"
                     /translation="MGKIEVINHPLIQHKLSILRRTDTSTKAFRELVDEIAMLMGYEV
                     LRDLPLEDVEIETPITKTVQKQLAGKKLAIVPILRAGIGMVDGLLSLVPAAKVGHIGM
                     YRDEETLQPVEYLVKLPEDIDQRQIFVVDPMLATGGSAILAVDSLKKRGASNIKFVCL
                     VSAPEGVKALQEAHPDVEIFTAALDERLNEHGYIVPGLGDAGDRLFGTK"
     gene            complement(26615..27082)
                     /locus_tag="VYO11_000567"
     CDS             complement(26615..27082)
                     /locus_tag="VYO11_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000138511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine/deoxycytidylate deaminase family
                     protein"
                     /protein_id="HEV1595169.1"
                     /translation="MTEKRLAWDEYFAAQALLIANRSTCKRAKVGAILVKDNKVISTG
                     YNGSVSGTEHCIDHECLVIEGHCVRTLHAEVNAILQGAERGVPKGFTAYVTHFPCLNC
                     TKQLLQVGCKRVVYINQYRMDDYAQYLYQEKGTELTHLPLETVQTALKEADLM"
     gene            complement(27101..27658)
                     /locus_tag="VYO11_000568"
     CDS             complement(27101..27658)
                     /locus_tag="VYO11_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEV1595170.1"
                     /translation="MSERRISEKSLENLRKSNQESNLLTREAIETALLQLLEKKELTK
                     ISISELVKRAGVSRAAFYRNYDSKEEILESVFKRTVHNIMEQLHHYDLKTDLYLVWVH
                     LFREARKEARVIQLALDYHLEKIFVQAMQEFLEKYHGKSKGVSSYLHSFWSSAIVSVL
                     LKWIKDGMKVPAEKIADLGLPFFKK"
     gene            27783..28628
                     /locus_tag="VYO11_000569"
     CDS             27783..28628
                     /locus_tag="VYO11_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEV1595171.1"
                     /translation="MTWKIIADSGCDYRQLPTPAINTTFVSVPLTIQVADQVFVDDAS
                     LDIDQMMETMYATAEASKSACPSPDDYLRAFEGAKNIFLVTITGTLSGSHNSAQLAKN
                     IYLEDHPDTKIHVIDSLSAGGEVDLLVEKLNDLIDQGLSFEEVVEAITAYQEKTKLLF
                     VLAKVDNLVKNGRLSKLIGTVVGLLNIRMVGKASETGTLELLQKARGSKKSVQAAYDE
                     LVKAGYAGGRIVMAQRNNEKCCQQLSERIRETFPQADIKILPTSGLCSFYAEEGGLLM
                     GYEID"
     gene            28687..29862
                     /locus_tag="VYO11_000570"
     CDS             28687..29862
                     /locus_tag="VYO11_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEV1595172.1"
                     /translation="MKHFDTIVIGGGPAGMMATISSSFYGQKTLLIEKNRKLGKKLAG
                     TGGGRCNVTNNGSLDNLLAGIPGNGRFLYSVFSQFDNHDIINFFTENGVKLKVEDHGR
                     VFPASDKSRTIIEALEKKITELGGQVATQIEIVSVKKVDDQFVLKSADQTFTCEKLIV
                     TTGGKSYPSTGSTGFGHEIARHFKHTITDLEAAESPLLTDFPHKALQGISLDDVTLSY
                     GKHVITHDLLFTHFGLSGPAALRMSSFVKGGEVLSLDVLPQLSEKDLVTFLEENREKS
                     LKNALKTLLPERLAEFFVQGYPEKVKQLTEKEREQLVQSIKELKIPVTGKMSLAKSFV
                     TKGGVSLKEINPKTLESKLVPGLHFAGEVMDINAHTGGFNITSALCTGWVAGSLHYD"
     gene            29882..30337
                     /locus_tag="VYO11_000571"
     CDS             29882..30337
                     /locus_tag="VYO11_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001081770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEV1595173.1"
                     /translation="MNRREAVEFVNMCMIKNGDKILVQDRVSPDWPGITFPGDHVERG
                     ESFVDAVIREVKEETGLIISKPQLCGIKNWYDDKDYRYVVLFYKTEHFTGELQSSDEG
                     KVWWEDFENLSHLKLATDDMSDMLRVFLEEDLSEFFYYKNGDDWLYDLK"
     gene            complement(30366..31106)
                     /locus_tag="VYO11_000572"
     CDS             complement(30366..31106)
                     /locus_tag="VYO11_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000274781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEV1595174.1"
                     /translation="MYHIKEAAQLSGVSVKTLHHYDKIGLLVPLKSENGYRTYSQEDL
                     ERLQVILYYKYLGFSLEKIAELLKEERTDLLPHLTRQLDYLTRERQHLDTLISTLQKT
                     IQEQKGERKMTIEEKFTGFSYQDNQKYHQEAVEKYGQEVMGQALERQKGHEDEATAAF
                     NQVFQTLAQNLQVGLPATATENQEQAAKLLQAIRTYGFDCSIEVFGHIGKGYVYNPEF
                     KENIDKFGSETAQYTSDAIAAYVQTNAE"
     gene            31189..32667
                     /locus_tag="VYO11_000573"
     CDS             31189..32667
                     /locus_tag="VYO11_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-dependent transporter"
                     /protein_id="HEV1595175.1"
                     /translation="MVFLTDLRKHNRIVKSINQTEGYLTTQVAFSYFEKGDQSLTMSE
                     KSQWGSKLGFILASAGSVIGLGSVWKFPYMTAANGGGGFLLIFLISTILIGFPLLLAE
                     FALGRSAGVSAIKTFGKLGKNNKYNFIGWIGAFALFILLSFYSVIGGWILVYLGIEFG
                     KLFQLGGTGDYAQLFTSIISNPAIDLGAQAAFILLNIFIVSRGVQKGIERASKVMMPL
                     LFIIFVVIIGRSLSLPNAMEGVLYFLKPDFSKLTSAGLLYALGQSFFALSLGVTVMLT
                     YASYLDKKTNLVQSGISIVAMNISISIMAGLAIFQARSPFNIQSEGGSSLLFIVLPQL
                     FDKMPFGTIFYVLFLFATVTSSVVMLEINVGNITNQDNSKRAKWSVILGILTFVFGIP
                     SALSYGVMADVHIFGKTFFDAMDFLVSNLLMPFEALYLSLFTGYIFKKALAMEELHLD
                     ERAWKQGLFQVWLFLLRFFVSSFQSSSLWSSLPNLCNQKGLE"
     gene            complement(32688..33632)
                     /gene="manA"
                     /locus_tag="VYO11_000574"
     CDS             complement(32688..33632)
                     /gene="manA"
                     /locus_tag="VYO11_000574"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HEV1595176.1"
                     /translation="MSEPLFLQSVMQEKIWGGAKLRDEFGYDIPSEKIGEYWAISAHP
                     NGVSKVANGRYEGTDLATLYAEHRELFGNRPEPVFPLLTKILDANDWLSVQVHPDDAY
                     GLEHEGELGKTECWYIIAADEGSEIIYGHNAKSKEELRQQIEDKNWDDLLTKVPVKAG
                     DFFYVPSGTMHAIGAGILILETQQSSDTTYRVYDFDRKDDKGNLRELHLEKSIDVLNI
                     GEPANSRPVTVKADDLRSTLLVSNDFFAVYKWEITGKVDFEKTADYSLLSVLAGQGQL
                     IVDGKNYPIQKGSHFILPSDVEAWTLEGQGLELIVSHP"
     gene            complement(33764..34045)
                     /locus_tag="VYO11_000575"
     CDS             complement(33764..34045)
                     /locus_tag="VYO11_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000380698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HEV1595177.1"
                     /translation="MDTPDENGYVADDYRITYLEAHIKAMRDAIYKDGVDLLGYTTWG
                     CIDSVSAGTGEMNKRYGFIYVDRDNVGNGTLKRSKKKSFYWYMSFIAMV"
     gene            34169..35251
                     /locus_tag="VYO11_000576"
                     /pseudo
     CDS             34169..35251
                     /locus_tag="VYO11_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            complement(35368..35715)
                     /locus_tag="VYO11_000577"
     CDS             complement(35368..35715)
                     /locus_tag="VYO11_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003017645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEV1595178.1"
                     /translation="MNLNQLDIIVSNVPQVCADLEHILDKKADYADDGFAQFTIGSHC
                     LMLSQNHLVPLENFQSGIIIHIEVEDVDQNYKRLNELGIKVLHGPTVTDWGTESLLVQ
                     GPAGLVLDFYRMK"
     gene            complement(35826..37601)
                     /gene="spxB"
                     /locus_tag="VYO11_000578"
     CDS             complement(35826..37601)
                     /gene="spxB"
                     /locus_tag="VYO11_000578"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000191798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HEV1595179.1"
                     /translation="MTQGKITASAAMLNVLKTWGVDTIYGIPSGTLSSLMDALAEDKD
                     IRFLQVRHEETGALAAVMQAKFGGSIGVAVGSGGPGATHLINGVYDAAMDNTPFLAIL
                     GSRPVNELNMDAFQEFNQNPMYNGIAVYNKRVAYAEQLPKVIDEACRAAISKKGPAVV
                     EIPVNFGFQEIDENSYYGSGSYERSFIAPALNEVEIDKAVEILNNAERPVIYAGFGGV
                     KAGEVITELSRKIKAPIITTGKNFEAFEWNYEGLTGSAYRVGWKPANEVVFEADTVLF
                     LGSNFPFAEVYEAFKNTEKFIQVDIDPYKLGKRHALDASILGDAGQAAKAILDKVNPV
                     ESTPWWRANVKNNQNWRDYMNKLEGKTEGELQLYQVYNAINKHADQDAIYSIDVGNTT
                     QTSTRHLHMTPKNMWRTSPLFATMGIALPGGIAAKKDNPDRQVWNIMGDGAFNMCYPD
                     VITNVQYDLPVINLVFSNAEYGFIKNKYEDTNKHLFGVDFTNADYAKIAEAQGAVGFT
                     VDRIEDIDAVVAEAVKLNKEGKTVVIDARITQHRPLPVEVLELDPKLHSEEAIKAFKE
                     KYEAEELVPFRLFLEEEGLQSRAIK"
     gene            complement(37808..40051)
                     /locus_tag="VYO11_000579"
     CDS             complement(37808..40051)
                     /locus_tag="VYO11_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HEV1595180.1"
                     /translation="MTEIVKASLENGIQKIRIRAEKGYHPAHIQLQKGIPAEITFHRA
                     TPSNCYKEILFEEEGILEPIGVDEEKVIRFTPQELGRHEFSCGMKMQKGSYIVVEKTR
                     KSLSLLQRFWITSIFTVPLVILMIGMLTGSISHQVMHWGTFLATTPIMLVAGKPYIQS
                     AWASFKKHNANMDTLVALGTLVAYFYSLVALFAGLPVYFESAGFILFFVLLGAVFEEK
                     MRKNTSQAVEKLLDLQAKTAEVLSDDSYVQVPLEQVKVGDLIRVRPGEKIAVDGVVVE
                     GVSSIDESMVTGESLPVDKTVGDTVIGSTINHSGTLVFRAEKVGSETVLAQIVDFVKK
                     AQTSRAPIQDLTDKISGIFVPVVVILGIMTFWVWFVLLRDSVVVLGASFVSSLLYGVA
                     VLIIACPCALGLATPTALMVGTGRSAKMGVLLKNGTVLQEIQKVQTLVFDKTGTLTEG
                     KPVVTDIIGDEVEVFGLAASLEDASQHPLAEAIVKRASEAGLEFQTVENFQSLHGKGV
                     SGRINGKQVLLGNAKMLDGMDISNTYQDKLEELEKEAKTVVFLAVDNEIKGLLALQDI
                     PKENAKLAISQLKKRGLRTVMLTGDNAGVARAIADQIGIEEVIAGVLPEEKAREIHKL
                     QQSGKVAFVGDGINDAPALSVADVGIAMGAGTDIAIESADLVLTTNNLLGVVRAFDMS
                     KKTFHRILLNLFWAFIYNVVGIPIAAGVFSGVGLALNPELAGLAMAFSSVSVLTSSLL
                     LNFSKID"
     gene            complement(40061..40432)
                     /locus_tag="VYO11_000580"
     CDS             complement(40061..40432)
                     /locus_tag="VYO11_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupredoxin domain-containing protein"
                     /protein_id="HEV1595181.1"
                     /translation="MLNSIVTIICIALIAFILFWFFKKPEKSGQKAQQKNGYQEIRVE
                     VMGGYTPELIVLKKSVPARIVFDRKDPSPCLDQIVFPDFGVHANLPMGEEYVVEITPE
                     QVGEFGFACGMNMMHGKMIVE"
     gene            complement(40443..40838)
                     /locus_tag="VYO11_000581"
     CDS             complement(40443..40838)
                     /locus_tag="VYO11_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HEV1595182.1"
                     /translation="MQISDAEWQVMKIIWMQGEQTSTDLIRVLAERFDWSKSTVQTLL
                     ARLVEKECLTRKKEGKFFVYSALLTLDQSRDLLVQDIKDKVCSRRIRNLLADLIVECE
                     FTQTDLEDLEAVISEKKSSAVTEVRCNCM"
     regulatory      41022..41120
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            41204..41995
                     /gene="thiD"
                     /locus_tag="VYO11_000582"
     CDS             41204..41995
                     /gene="thiD"
                     /locus_tag="VYO11_000582"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HEV1595183.1"
                     /translation="MTYLPVALTIAGTDPSGGAGIMADLKSFQARDAYGMAVVTSLVA
                     QNTRGVQLIEHVSPQMLKAQLESVFSDIPPQAVKTGMLATTEIMEIIQPYLKKLDCPY
                     VLDPVMVATSGDALIDSNARDYLKTNLLPLATIITPNLPEAEEIVGFSIHDPEDMQRA
                     GRLILKEFGPQSVVIKGGHLKGGAKDFLFTKNEQFVWESPRIQTCHTHGTGCTFAAVI
                     TAELAKGKSLYQAVDKAKAFITKAIQDAPQLGHGSGPVNHTTFKD"
     gene            complement(42205..42837)
                     /locus_tag="VYO11_000583"
     CDS             complement(42205..42837)
                     /locus_tag="VYO11_000583"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HEV1595184.1"
                     /translation="MNREALRLYLVTNRYQDSVESFLAKIETACRSGVTIVQLREKNL
                     TTNQYYQLAKQVKEITDAYQVPLIIDDRLDVCLAVDAAGLHIGDDELPVSVARKVLGP
                     EKILGVTAKTVKRALEAEKSGADYLGTGAIFPTTTKENAPITLISTLKTICQTVAIPV
                     VAIGGLTSENIDQLMGTGIAGVAVVRDLMQAEDIEAKTQAFLTKLHDILS"
     gene            complement(42830..43633)
                     /locus_tag="VYO11_000584"
     CDS             complement(42830..43633)
                     /locus_tag="VYO11_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HEV1595185.1"
                     /translation="MQEFTNPFPIGSSSLIHCMTNEISCEMLANGILALGCKPVMADD
                     PREVLDFTKQSQALFINLGHLSAEKEKAIRMAASYANQSSLPMVVDAVGVTTSSIRKS
                     LVKDLLDYRPTVLKGNMSEIRSLVGLKHHGVGVDASAKDQETEDLLQVLKDWCQTYPG
                     MSFLVTGPKDLVVSKNQVAVLGNGCTELDWITGTGDLVGALTAVFLSQGKTGFEASCL
                     AVSYLNIAAEKIVVQGMGLEEFRYQVLNQLSLLRRDENWLDTIKGEVYE"
     gene            complement(43633..44157)
                     /gene="thiW"
                     /locus_tag="VYO11_000585"
     CDS             complement(43633..44157)
                     /gene="thiW"
                     /locus_tag="VYO11_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001225563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy coupling factor transporter S component
                     ThiW"
                     /protein_id="HEV1595186.1"
                     /translation="MRKHQLQVHKLTILSMMIALDVVLTPIFRIEGMAPMSSVVNILA
                     GIMMGPVYALAMATVTAFIRMTTQGIPPLALTGATFGALLAGLFYKYGRKFYFSALGE
                     IVGTGIIGSIVSYPVMVLFTGSAAKLSWFIYTPRFFGATLIGTAISFIAFRFLIKQEF
                     FKKVQGYFFSERID"
     gene            complement(44162..44854)
                     /gene="tenA"
                     /locus_tag="VYO11_000586"
     CDS             complement(44162..44854)
                     /gene="tenA"
                     /locus_tag="VYO11_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiaminase II"
                     /protein_id="HEV1595187.1"
                     /translation="MEFTDIAMELSKKAWQASFHHPFILQLQEGNLEPAIFRYYLIQD
                     AYYLKAFSEIYHLLADKTSNQEMKRLLKQNAQGLVEGELFIRQQFFKELEINDQEMEQ
                     HPIAPTCYHYISHIYRQFAEPNLAIAFASLLPCPWLYHDIGKSLNLKPSPNPLYQQWI
                     ETYITDELEQQIREEGALVNQLYRESDETDKQKMLDAFHISVHMEAKFWEMAYQHQTW
                     KSDLQSLEKGEE"
     gene            complement(44865..45515)
                     /locus_tag="VYO11_000587"
     CDS             complement(44865..45515)
                     /locus_tag="VYO11_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt ABC transporter permease"
                     /protein_id="HEV1595188.1"
                     /translation="MVKVATQTPIISLFLLILSLETSFIPSIALNLSVVAFCILFMLY
                     YRRFKMLAWMIILAILPSFANYWAVQLHGDASQAVMLGTRAFVTVCIGLVFVSSISLK
                     ELLLYLAQKGLSRSWSYALIVVFNSFPLIQQEIKSLKEACLLRGQELHFWSPLIYSKV
                     LMTVFRWRHLYLRALSAHGYDEHAQLKNSYRTFYIPKKTKLIYLLFFLLLQTSLFL"
     gene            complement(45517..46902)
                     /locus_tag="VYO11_000588"
     CDS             complement(45517..46902)
                     /locus_tag="VYO11_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1595189.1"
                     /translation="MGLELRAIQSPIFSEPFDFTFHAQAFTLLVGSSGSGKSSLFQVI
                     AQVSSLPYSGQVLIDGSEVSQLSIIARIQKVGILFQNPNHQFTMENLFEELIFTLENI
                     GYHLQEIDSKIAEVVQQCRCEAILHRPIHHLSGGEKQKAAMAVLFAMNPRVYLLDEPF
                     ASIDRKSRIEILEILKELALDGKTVILCDHDLSDYKAYIDHMVELRDGKLREVFQIPS
                     YEMTQVASKEVASSPELFHMDRTTCEFGNRSLFSIADFTFYQGISCILGDNGVGKSTL
                     FRSILQFQKYKGRIAWKGTVLKKKKSLYRELTSIVQEAEKQFIRVSLREELQLDGPDS
                     ERNQRIFQALRYFDLEQAVDKSPYQLSGGQQKILQLLTILTSKASVILLDEPFAGLDD
                     RACHYFCKWIVEERNQGRSFLLISHRLDPLISVVDYWIEMTSQGLRHVKEVTITKPLT
                     SQSSNTQGEVR"
     gene            complement(46903..47463)
                     /locus_tag="VYO11_000589"
     CDS             complement(46903..47463)
                     /locus_tag="VYO11_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEV1595190.1"
                     /translation="MLKKWQLKDVILLAFLSIFFGGVFVGSGYVYNIFSLLLTPLGLQ
                     AFANEILFGLWCMAAPIAAIFVPRVGSATIGEVLAALAEVLYGSQFGLGALLSGLVQG
                     LGSEFGFIVTKNRYESWLSLTANSIGITLVSFVYEYIKLGYYAFSLPFVLSLLVVRFI
                     SVYFFCTILVRAIVKLYHQFATGGKA"
     regulatory      complement(47724..47812)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(48021..48650)
                     /locus_tag="VYO11_000590"
     CDS             complement(48021..48650)
                     /locus_tag="VYO11_000590"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000468574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HEV1595191.1"
                     /translation="MFHKELLKLYFICGTTTCQGKNLYTVVEEALKGGITLFQFREKG
                     EGALEGLEKLELAIQIKELCKKYNVPFIVNDDIDLAMEIDADGVHVGQDDIGVDEIRK
                     LMPDKIIGLSIRNEEEFQQSKVEYVDYVGVGPVFDTQSKDDAGGAIGYEGLELMRKLL
                     PQMPLVAIGGIQTKHIKDIIKTNMDGVSIISAISYAKNIEKTVREMSEQ"
     gene            complement(48652..49434)
                     /gene="thiM"
                     /locus_tag="VYO11_000591"
     CDS             complement(48652..49434)
                     /gene="thiM"
                     /locus_tag="VYO11_000591"
                     /EC_number="2.7.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HEV1595192.1"
                     /translation="MTSLKLLKEKAPLVICITNDVVKNFTANGLVALGASPAMSEFPA
                     DLEDLLKYAGGLLINIGTLTDENWKLYQAALKIAEKYNVPAVLDPVACGAGEYRKKVA
                     DDLINNYKLAAIRGNAGEIASLVGIDVASKGVDSAGVDNIDEIALAANEKFNIPIVVT
                     GEVDAIAVNGEVVTIHNGSAMMPKVIGTGCLLGAVVASFIGLEKGQELKSLETAMLVY
                     NIAGEMAEKRPNGHLPGTFKVEFINALYEITDEDVKEFKRVK"
     gene            complement(49677..50345)
                     /locus_tag="VYO11_000592"
     CDS             complement(49677..50345)
                     /locus_tag="VYO11_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000449895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TenA family protein"
                     /protein_id="HEV1595193.1"
                     /translation="METQNYAFQPGLTVGELLKSSQKDWQAAINHRFVKELFAGTIEN
                     KVLKDYLIQDYHFFDAFLSMLGACVAHADKLESKLRFAKQLGFLEADEDGYFQKAFKE
                     LKVAENDYLEVTLHPVTKAFQDLMYSAVASSDYAHLLVMLVIAEGLYLDWGSKDLALP
                     EVYIHSEWINLHRGPFFAEWVQFLVDELNRVGKNREDLTELQQRWNQAVALELAFFDI
                     GYDV"
     regulatory      complement(50560..50648)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(50902..52038)
                     /gene="lctO"
                     /locus_tag="VYO11_000593"
     CDS             complement(50902..52038)
                     /gene="lctO"
                     /locus_tag="VYO11_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate oxidase"
                     /protein_id="HEV1595194.1"
                     /translation="MSYKTSNAEGHVDFINTYDLEPMAQQVIPKAAFGYIASGAEDTF
                     TLRENIRAFNHKLIVPHTLCNVENPSTEIEFAGEKLSSPIIMAPVAAHKLANEQGEVA
                     TARGVHEFGSLYTTSSYSTVDLPEISEALQGTPHWFQFYFSKDDGINRHIMDRVKAEG
                     YKAIVLTADATVGGNREVDKRNGFVFPVGMPIVEEYLPEGAGKSMDFVYKSAKQRLSP
                     RDVEFIAEYSGLPVYVKGPQCREDVERSLAAGASGIWVTNHGGRQIDGGPAAFDSLQE
                     VAEAVDRRVPIVFDSGVRRGQHVFKALASGADLVAIGRPVIYGLALGGSVGVRQVFEH
                     LNAELKTVMQLSGTQTIEDVKHFKLRHNPYNPTFPVDPRDLKLY"
     gene            complement(52663..54153)
                     /gene="lysS"
                     /locus_tag="VYO11_000594"
     CDS             complement(52663..54153)
                     /gene="lysS"
                     /locus_tag="VYO11_000594"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003055423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HEV1595195.1"
                     /translation="MSTEHMEELNDQQIVRREKMAALREQGIDPFGKRFERTANSQEL
                     KDKYANLDKEQLHDKNETATIAGRLVTKRGKGKVGFAHLQDREGQIQIYVRKDAVGEE
                     NYEIFKKADLGDFLGVEGEVMRTDMGELSIKATHITHLSKALRPLPEKFHGLTDVETI
                     YRKRYLDLISNRESFERFVTRSKIISEIRRYLDQKGFLEVETPVLHNEAGGAAARPFI
                     THHNAQNIDMVLRIATELHLKRLIVGGMERVYEIGRIFRNEGMDATHNPEFTSIEVYQ
                     AYADFQDIMDLTEGIIQHAAKSVKGDGPVNYQGTEIKINEPFKRVHMVDAIREITGVD
                     FWQDMTLEEAKAIAAEKKVPVEKHYTEVGHIINAFFEEFVEETLIQPTFVYGHPVAVS
                     PLAKKNPEDQRFTDRFELFIMTKEYGNAFTELNDPIDQLSRFEAQAKAKELGDDEATG
                     IDYDYIEALEYGMPPTGGLGIGIDRLCMLLTDTTTIRDVLLFPTMK"
     gene            complement(54281..>54376)
                     /locus_tag="VYO11_000595"
     CDS             complement(54281..>54376)
                     /locus_tag="VYO11_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate oxidase"
                     /protein_id="HEV1595196.1"
                     /translation="YDLEPMAQQVIPKAAFGYIASGAGDTFTSFQ"
BASE COUNT        16113 a        11792 c        10158 g        16313 t
ORIGIN      
        1 attttcatct aatttaaata actttcaatt aagtgtgaat tttgcttaaa atcattaaaa
       61 aacaccccat ggtgtgaacc atgaagtgtt gtaaatgctg tgttgtagct agttcttagc
      121 gtttagagaa ctggctagct ttacgagctt tcttaagatc tggtttccaa aatactttga
      181 gtacacttat ggtattgatg cccctaaaca tctaaaaact ctggtagaaa aagggtatgc
      241 tcttgtcgaa acttcttttg actcacttga ccatctaaat actaccatga aaaagaatat
      301 cctgaagaag ggagttactg gactttctaa aatgaaatct tgcgacctgg atcaagccct
      361 tcatgagcat ttttcagaag aagaattagc tggtcacttt catgtccttc tatggacttt
      421 tttacaatgg cattgctatc acacccaata cctatctaag cgcctggttc gtaaacttta
      481 ttgcagctct tcctctaaat ttcctaattg ttgaaccaat tgcccgtttt atactaagtt
      541 cttttcagaa accatttact ggggaagaag ttgaagattt tcaagatgat gatgaaatcc
      601 caactattat ctaagccagt tctgtaaact actaatattt gaaatccact tccttttagg
      661 gtacaatggt ataaatgaat ttttgagagg atcagaatga aaaaactagc aacccttctt
      721 ttactgtcta ctgtagccct agctgggtgt agcagcgtcc aacgcagtct gcgtggtgat
      781 gattatgttg attccagtct tgctgctgaa gaaagttcca aagtagctgc ccaatctgcc
      841 aaggagttaa acgatgcttt aacaaacgaa aacgccaatt tcccacaact atctaaggaa
      901 gttgctgaag atgaagccga agtgattctc cacacaagcc aaggtgatat tcgcattaaa
      961 ctcttcccta aactcgctcc tctagcggtt gaaaatttcc tcactcatgc caaagaaggc
     1021 tactataacg gtattacctt ccaccgtgtc atcgatggct ttatggtcca aactggagat
     1081 ccaaaagggg acggtacagg tggtcagtcc atctggcatg acaaggataa gactaaagac
     1141 aaaggaactg gtttcaagaa cgagattact ccttatttgt ataacatccg cggtgctctt
     1201 gctatggcta atactggtca accaaacacc aatggcagcc agttcttcat caaccaaaac
     1261 tctacagata cctcttctaa actccctaca agcaagtatc cacagaaaat tatcgaagcc
     1321 tacaaagaag gtggaaaccc tagtctagat ggcaaacacc cagtctttgg tcaagtgatt
     1381 ggcggtatgg atgttgtgga taagattgct aaagccgaaa aagatgaaaa agacaagcca
     1441 actactgcta tcacaatcga cagcatcgaa gtggtgaaag actacgattt taaatcttaa
     1501 aaaccaaaaa aaatacagta tccacattcg gtactgtatt tcttttactc tcattcttaa
     1561 gttaaattat taaaatccca tatttggtct atccagcctt cataaaagtc tagctcgtgg
     1621 cagaccataa ggatagatcc cctatattct ttgagagcgc gtttgagctc atcctttgca
     1681 tccacatcca aatggttggt cggctcgtcc agcactaaaa cgttgttttc acgattcatc
     1741 aagagacaga aacgaacctt ggcttgctct ccccctgata atacttgaat ctggctttca
     1801 atatgtttgg ttgtcaaacc acaacgggca agggctgcac ggacttctgc ttgattaagg
     1861 gcaggaaagg cattccagac agcttcaaga ggagtttggc gattaccgcc ttctacttcc
     1921 tgttcaaaat aaccaagttc taaataatct ccacgctcca cttccccagc gattggcgag
     1981 ataatgccca agagactctt caagagagtt gtttttccaa taccattagc accaataatc
     2041 gcaacctttt gattgcgttc gaaggtaaga tttaaaggct tagtaagagg acggtcgtaa
     2101 ccaatttgca agttcttggc ttggaagata aagcgccctg gtgtacgagc tggtttgaaa
     2161 tcaaaggatg gttttggttt ctcactttgg agttcgataa tatccatctt atccaatttc
     2221 ttttgacgag acatagccat attacgagtt gcaacacggg ctttattacg agccacaaag
     2281 tccttgaggt ctgcaatctc tttctgctgg cgttcgtagg ctgcctctag ctgagatttc
     2341 ttcatagcat aaacttcttg gaactggtag tagtcaccag agtaacgcgt cagctgttga
     2401 ttttccacat gatagacaat attaataacg tcattgagga atggaatatc gtgcgaaatg
     2461 agaacaaagg cattctcata gttttggaga tagcgcttga gccaatcaat atgctcagca
     2521 tccaagtagt tggtcggctc gtccaacagc aagatatcag gcttttcaag gagaagtttt
     2581 gccaaaagca ccttggttct ttgcccacct gacaaagaag ttacatccgt atccatgcca
     2641 aagtccataa caccaagagc acgcgctact tcgtcaatct tagcatccaa ggtatagaaa
     2701 tcacgactct ccagacggtc ttgaagttct cctacttctt ccatgagagc atcaacatcc
     2761 gcgccgtctt cagccatttt catatagagg tcattgatac gagcttcagc tttgaaaagc
     2821 tcatcaaaag ccgtacggag aacatcacgc accgactgtc tttcagcaag gacagagtgc
     2881 tgatccaagt aaccagccgt cacatatttg gaccactcaa cctttccttc atctggcagc
     2941 attttaccag tcacgatact cataaaggtt gattttcctt caccattggc accgaccagg
     3001 ccgatatgtt ctcccttgag gagacggaag gacacatctt caaaaattgc acggtcacca
     3061 aaaccgtgac tcagattttt aacttctaaa atactcattt taattcctta tcttgttttt
     3121 atgtaatcgt ttataaagga gccaagccag atagccaccc aaagtgttgg tccacaaatc
     3181 atcaatctca aagacgcgat tgaaatcaaa gaaaaagtct aagattaatt gcgtacactc
     3241 gattccaaga ctcacaagaa aactaaaaag aaggaccttt tttgttttcc gcaaatttgg
     3301 aaatagataa aggagttgga aaatcagagg aaaaaacaag aagacattga ggatattttg
     3361 taaaaaaatc caacataatt gtccaatgtc actcacttcg cccagtttcc agagagaatt
     3421 gaaaggagtc aaaagaaaaa ccaggcgtcc aagatgctga atacctggag ttcccactcc
     3481 cacggtagat tgttcttgag gagtaaagca aaaacagaca atgcaaatgc tatagaaaat
     3541 gactccccag accaaaatat gattataagt cttcttcatc attaaggatt taccgctgcg
     3601 actgccttct ggcggtcacg tttcattgtg ttagagcgca attgtccaca agctgcgtca
     3661 atatctgtac catgctcttg acgaaccaca cagttgaccc cttttttctt aagcgtatca
     3721 tagaaagcca acacgcgctc tttgggacta cggctatatt ggtcatgctc actaactggg
     3781 ttataaggaa tcaagtttac ataagacaat ttcttgatgt tcttgagcaa ttcagtcaat
     3841 tccaaggctt gttctacacc gtcgttgact tcattaagca tgatatattc aaaggttaca
     3901 ccacggtttg ttgtctcaat gtagtattca atagcagcaa agagtttttc aatcggaaag
     3961 gcacggttaa tcttcatgat acttgaacga agttcattgt taggtgcgtg aagagacacg
     4021 gcaagattga cctgaacccc ttcatcagca aagtcacgaa ttttatgagc caaacctgag
     4081 gttgaaaccg tgatgtgacg agcaccgata gccattcctt tatcatcatt gatagtacga
     4141 aagaaattca agacattgtt gtaattatca aagggctcac cgattcccat gacaacgata
     4201 tggctgacgc gttcatcctg accacgctca gcaaagtatt tctgaaccag catgatttgc
     4261 gctacgattt caccgttatt gaggtcacgt tgcttcttaa tcaaaccaga ggcacagaag
     4321 gtacaaccga tattacagcc gacctgagtg gtcacacaga cagataaacc atagtgttga
     4381 cgcatgagta cagtctcaat taacataccg tcgggcaatt caaagagata tttgactgta
     4441 ccatcagcag actcttgcac aatacgttgt ttcaagggat tgaccacaaa ctggtcattg
     4501 agcttagcaa tcaaatcctt ggaaaggttg gtcatttctt caaatgactg cacacgttta
     4561 cggtagagcc attcccagat ttgatctgca cggaatttct tttctccctg ctccaatacc
     4621 cattcctgca tggtttgatg tgccaaacta tgaattgagg gtttcatttc ttctccttat
     4681 tctctactca cttctgacga atgacaaaat gacgttgtcc cttgtcctct ttctgagaat
     4741 gctggtcttt ctgacgacgt ctatttttct tatctgcatt cgactttcgt ttagtttgag
     4801 tcggtttctt tccttttcta gaaggtgttt cttcttccgt cttacgcatt ttcttgtcaa
     4861 atgatgctcg cttaggggct tcattttcta agacaaaata ggaacaacca taactacaat
     4921 actctaaaag gtagtcttgt aaacgactga ttttttcaag tttttcttct gttcggtcat
     4981 ccttgtaaaa acctcgtagg cgaagctgtt cgttgctcca gtcccccacg atataatcaa
     5041 acttggttaa tacttctgaa aaacgctgat taaaagtcgt cacatcaaag gcatccttga
     5101 tattttcaac caaggaaaaa gctatccctt ccgtttcgac cttgtccccg tgtaaatgga
     5161 actccggacc aggaaacttg ttatagttgt ataattcagg tgcaatttct tttcgcatag
     5221 atatcctttt ttcacgatta cttaatactt tattctacca taatttctag cagttagcac
     5281 gtttctcata aaaatgaaaa aagtctgacg attttgtcag accagaatct tataacctaa
     5341 aaagagaaga acaattcttc cctccaacta tcattattta gcagctgcgt acaattcatc
     5401 tactttattc cagttgatta ctgaaaagaa agctttgatg tagtcaggac gcacgttgcg
     5461 gtatttcacg tagtaagcat gttcccaaac gtccaagccc aagattggtt ttttaccttc
     5521 tgagattggt gtgtcttggt ttgctgttga agtcacttca agtttccctt ctttgttgac
     5581 aaccaaccat gcccaacctg aaccaaaacg agttgttgct gctgcagtga aggctgcttg
     5641 gaattcttca aatgaaccaa atgttgcatc gattgctgct gccagttctg ctgaaggagc
     5701 tgttttctcg ggagtcatca attcccagaa aagagcgtgg ttcaagtgtc cgccaccatt
     5761 gttgataagt gcttgacgga tatcagctgg gatagattct acatcagcaa gcaaggcttc
     5821 aaggtcttca ccgatttcag ggtgtttttc taaagctgca ttggcattgt tgacataagt
     5881 ttgatggtgt ttgtcatggt gcaaatgcat tgtttccgca tcgatgtatg gttccaaagc
     5941 gtcgtatgca tatggaagtt ctggtaagat aatagccatc tgtaatacct ctttttcttt
     6001 ctatatgaaa atgataacgc aaacattcac ttttttcaag ttttttgctt atagataagg
     6061 aaatcactga catactttct aataaaataa gcaaatcagc aagaaaccca cgacaagata
     6121 gtcctgacgc gggttgtagt ttcaacaaat gtcaattgac ctgactagca atctgtaaga
     6181 gtgccttttc aaaaaggaaa cctttttcat aaagacctgt cttaatctga tagtctgtct
     6241 caatcaaata ggaaatagct tgcttcaaaa agctcaaaga aagtcctctc gaatctctta
     6301 atgcaaactt gatttgataa ggatttgggt tacgtcccag ataactacct aaactacttg
     6361 caatctgcga ttctgtttgg ccagactccg ccaaaatctt cacctgagta aaagtccgaa
     6421 attgtcccag catgactgca atcagtttga tttcatcttc cccttgcaag gtcaagtctc
     6481 tcaccaaatc gcgcgcctga tccatctttt tagtcagaat aaactgagtt aaatcaaaaa
     6541 tattgtcctg caaggtcttg ggaattgcgt taacaatatc ctcttcctca ataacagaat
     6601 tcgccttata ggactgtaaa aagagaagat ttttctggat ttcgctaaat tgaaaccccg
     6661 acttgatgag gagattttca aaagaatgat tggtaaactg cagaccttgt ttctgactcc
     6721 acttttggaa atactggcgc aattcttgtt cttttacttc tactgcatcg aagaccttgg
     6781 catcacgctt aagtaatttg actaaccgtc ttttgctatc cagctttcct tctgcaaaga
     6841 ttatcaactt ggttgttgga gaagaattgt caaggtattc ctcaaatgac ttaagctcat
     6901 catctgtcaa aaagcgtttc ttagcagtcg tgatatccat aaaataatct aatatcacga
     6961 ttttctcatc cgcaaagaaa ggaagactga ccaactccag ttccacatcc ttgtaaacta
     7021 cttctttcat atcaaagtag gcaaagttga ggtcagcaga atcataccca atctgtttca
     7081 acacttgact cttcatcact tcaaactgac cctgatctgt ccctgtaaat aggctcaggc
     7141 tcggtaaatt tgataaagtc aacttctgac tttcttcaat ggctagcatc gtctctcctt
     7201 tcttcagatt tttcgattta atttagtcaa tatagcgcaa tttcccacgg aaatcttcta
     7261 agctctcgta gcctttttcc gccatgattg ctttcagttc attggtaatg cggtcaaaag
     7321 cactgacgcc ttctttgtga agggtcgttc ccacctgcac catacttgct ccacagagga
     7381 tgtgttcaaa ggcatctcga ccagtcagaa cgccacctgt tccgataatt tggatttgag
     7441 gatttaaacg ttgataaaag gcgtgaacat tggctagagc agtcggtttg atgtattctc
     7501 caccaattcc accaaaacca ttcttaggcc gaataacgac agattcgtct tctatataga
     7561 ggccgtttcc gatagagtta acgcagttta caaacttgag cggatatttg ttgaaaatag
     7621 ctgccgcttg atcaaagtga acaatatcaa aataaggtgg caatttaatt ccaagaggtt
     7681 tggtgaagta agcaaacact tctgccaaaa tccggtctgt tgtctcaaaa tcataggcaa
     7741 tctgaggttt acctggaaca tttggacagg aaagatttag ctcagtcaga ccacgaaaat
     7801 cactctcttg gacttttttc aaaatagtat gggtttcctc tggagacatg ccgaccagag
     7861 ataagaagaa agttcggttc gactcttttt cctgcaaatc caaaagataa tccaaataat
     7921 agtctaagcc attatttggc aagcccatag agttgatgga accaagtgga acatcttggt
     7981 agcgtggctc aggattcccc tgacggaagt ccaaggtcgc tgtcttagta acaaaggttc
     8041 ctgccgctga gtttttgacc tcttctaact cctctatcgt catacaagcc acacctgctg
     8101 cattcatcaa gcaattgtca aactcaaaac cagcaatttg tgttttcgtt gataccatga
     8161 ttctaatcct ccagatttct tttattgcta atattatacc ataattttaa ttctaggttt
     8221 actagattct gtggttctat ctatttattc ggaaaagaaa gtctagtaca gaagtcatgc
     8281 tatggaaaca gctagtgtat tagaagtttg aacaaggctt gggtaacaga cttttgaatg
     8341 aagtccaagc aacaaggaga aatctcaacc atgagtccat tccatgactc tgttgctcta
     8401 gaaaaccttg caatagtcaa gtgataacga ataaaacttt ggattgaaat atccccaaga
     8461 ttatctatta cgaggagaaa tcttaacctt tatcattttt aaagaaatat agtaaaatga
     8521 aacaagaaca ggagaaatcg atcaggacag tcaaattgat tgctaacaat gttttagaag
     8581 ttgaggtgta ctattctagt ttcaatctac tatacatgta aatctctact ttcgcaaaat
     8641 ggattttcag aacagtatcc cagtatagtt aaaaactata aaaaagagag gacgttcccc
     8701 tcttaaaatc ttattttact gcttctttca aagcatctac cttatccaaa cgttcccatg
     8761 gaagatcaat atctgtacgt cccatgtgac cgtaagccga tgtttgacgg taaattggac
     8821 gcttgaggtc cagcatttgg ataatccctg cagggcgaag gtcaaagatt tgacgagccg
     8881 ctttttcaag ttgactttca gctactgttc ctgtaccgaa agtatcgata cgaacagaaa
     8941 caggttgcgc aacaccgata gcataggcca actgcacttc tgccttctta gcaaggcctg
     9001 ctgcaacgat attcttggca atatagcgag ccgcataaga ggctgaacga tccaccttag
     9061 tcgcatcttt accagagaag gcaccaccac catgacgaga gtagccacca taagtatcta
     9121 caataatctt acgaccagtc aaacctgagt ccccttgagg accaccgatt acaaaacgac
     9181 ctgtcggatt gataaagaat tttgtcttat catcaagata agaagatgga ataacttctt
     9241 tgatgacctt gtcaatcaca tcttgatgga tttgttcatt agtggcctct ggatcatgct
     9301 gagtagaaat aacgactgta tctacacgta ccggacggtc attttcatcg tactcaactg
     9361 taacttgtga ttttgcatct ggacggagat agctaatttc tccagactta cgaagttctg
     9421 ccagacgacg aaccaattta tgactgagtg caattggcaa tggcataagc tcttctgttt
     9481 catctactgc aaatccaaac atgagccctt ggtcacctgc tccaatcaag tccagtggat
     9541 cttgatcagc atttccgcga acctccaagg cttcgttaac accttgagcg atgtcaggag
     9601 attgttccac caaagatggg tgtactccca ccgtctcagc agaaaatcca tattctgtat
     9661 tggtataacc aatctctgca atggtatcac gaaccacacg gttaatatcc acataggcat
     9721 ttgtagaaat ttcaccaaaa acgtggacag aaccagtata tacagctgtt tcagcagcaa
     9781 cgtgcgcctc tggatccttt gctaaaatag catccaaaat cgcatctgaa atttggtctg
     9841 caatcttatc cggatgcccc tcagatacag attcagacgt gaataattta cgttctgaca
     9901 taaaaatgtc cccccttaaa aaatattgtt atagagttac aaagtactga taggaaaact
     9961 cttcgtaata aatacctacc atcttatcgg gactatataa ctttatcatt ataccatttt
    10021 taatcgcaat ttgcagtctt taatgtagtg tttcggttta gatagttcgt tctcataaag
    10081 caaaaagttg gagctcagta ctccaacaat ttctattaaa atgtttggcg tttagcttta
    10141 cgctctgcac gaccgcgagc gcgattttca gcacgcttag ttttacggcg cttttcatca
    10201 accgcccatt gaattttctt cttataaccc ggtttgactt ttttcttttt ctttttaacc
    10261 aaaccaatca tttcgatatc aagtttatct tgttttttct cacggttggc acgacgatca
    10321 cggtcatagg tatcttgaaa ttccccatct ttgaccatct taggactaaa cttgattccc
    10381 aatttctcca actcacggat atccgagtca tcacttggct gataaagggt aatagctgta
    10441 cctggtaggc catttcgtcc agtacgacca acacggtgaa caaaaaaaga taagtcttgc
    10501 ggaatggcat cattgatgac atggctgaca ccttcaatgt caatcccacg cgctgctaaa
    10561 tctgttgcga caatatactc aaaatccaga ttttgcacct gattcatgat tcgcttgcgt
    10621 tcacgagggg caatatcgcc atggattttt gcaaccttca agccttgagc agtcagatat
    10681 gaatgcaatt catcagcacg cgttttagtg ttaacaaaaa tcattgccaa atacggctgc
    10741 atcaactgag tcaactggta aatttgagca ttcttatcat gtcccttggt cgaaatcaac
    10801 caattatcaa tggtgtcaga aataaccgtt ttagtcttaa ttttctccat aacaggattt
    10861 gataagtatt ttttcaagaa tggttgcagt ttttgtggga tagtcgctga gaagaccatg
    10921 aattgcaagt cttttggaag actgccagca atcttatcaa cagtttccaa gaatcccata
    10981 tccaaggtca tatctgcttc atcaacaaca aatgtcttgg ctttatgaat agctaaatca
    11041 ccagatttaa ccaagtcgta gatacggcct ggtgttccaa taacaatatg aggctgattg
    11101 ctttccaatt tctcaatctg gcgagcctta tccgtaccac ccacataatt aaccacacga
    11161 acttcgacat ctgagtgagc tgaaatctga cgcgctactt ggtaaatttg agtagccaac
    11221 tcacgactcg gtgcagtaat cactgcttgt acactatcgc tagcttcatc taattgctgg
    11281 aaaatcggta acaagaaagt gtgagtctta cctgaacctg tttttgattc tcctactagg
    11341 tcacgacctg ccaaaacaat aggaatcaac ttgtcttgca cctctgttgg agttgtaaat
    11401 tttaactcct tcaaggcttc tctaatatag tttttaaatt gaaatttcgt aaatgacata
    11461 acatcctcga ttctatctat cttatcaatt ataccatatt ttattccatt acagtagtct
    11521 cacttattta ggctatttcc agtagcttct ctagtaagaa aaggctggaa ttttatagtt
    11581 ccaacctctt ttcagttatt atttccagtt taacatagca ttcaagccat agtgatcact
    11641 cacttgtgga ctcttgttac catcaaatac gacatgtaaa ttttccaccg ctaactcttt
    11701 ggtagtaaag acataatcga ttcgaagggg ttcagtgttc cctttccagc catcaatttc
    11761 aggcggaaca gtatagctac cacttttctc ttgagcaact tcaaatgcgt cttgtaagcc
    11821 taatggacta gctaaaatag cttggtaacc ttcctgacct gctgggttgt taaaatctcc
    11881 agctagtaaa agtggcttgt tcaatttttt caagacaacc tcaaatcgtg cccattcttc
    11941 ttgaaaacct ttatcccacc aagagagatg aacactggca actgctagct ccttgccatc
    12001 gactacagtt tcagctaggg caacacggcg agtatgatag tctgttggat catccacatc
    12061 tgaaaccaaa atttctctgg cttcaatagg tgttttagac aagatagcca caccttcgtg
    12121 gtagcggtca tagccgatat ggttataggc ccaggtccag tagtaatttt tcccttgctc
    12181 agataacttt tcaaccaaga gtctaacata gtgatcttgg tgaataggct cagctgctgg
    12241 caaagcttga taaaggtcat taacctccac ctctgacgag gtcatctcct gattaatttc
    12301 ttggaaacaa atcaaatcat agtccttttc aagaatatct tcaagcaaaa tctggaattt
    12361 ttcctctgct tctttctcca tccaactatg agtattgagt gttaaaaatt tcattctttt
    12421 ctcccaaaat aagaggttgg aatacagctt ccaacctcaa gtatattaca attctacttt
    12481 agcaactgct gttttagctg caagagaacc tgttttttct aatttaactg atttaattgc
    12541 atcaccattt gtgaagacaa ctactgttga agtttcacgt cctgctgcac ggatagcatt
    12601 caagtcagct gtgacaagga gatctcctgc tgcaactttt tgtccttcag caacatgaac
    12661 tgtaaatggt ttaccttcaa gacttactgt gtccaaacca atgtgaacca atacttcaag
    12721 acctgcttcc gtcacaatac caaaagcatg ttttgttggg aagatgcttg atacagtacc
    12781 tgaaactgga gatacaatgt ttccatttgc aggttctact gcaaatccat cacccatcat
    12841 tttttgagca aatactggat cctttacttg ttccaaagca acaacttgac cgtctgctac
    12901 tgagtaaact tcctcagtaa gatctttgaa gtgaacagtg ttttgttgta cttcagtcat
    12961 ttggcttgga agagtttcag gaatgatttc acctgaatca aggatatctt ggatatcaga
    13021 tttcaaaatg tcagcttttg gaccgtagat agcttgaacc ccttgtcctt tcatcacaag
    13081 acccatagct ccttctgctt tccattgctc tgcatttcct actttatctg catctttaac
    13141 agttacacga agacgagtca tacatgcatc aacatcaacg atgtttacac gtccaccaag
    13201 aaggttgata atgtttacag cttgagagcc tgctgcaact ttcacttcgc tgctggtttc
    13261 ttctgaacct tcagcagttt cgtagtttcc gttgcgccct ggagttgcgt agttgaattt
    13321 ttgaatcatg aagtttgcga taaagtacat gattacagca aagagaacag ttacccaaac
    13381 gaagttaacg atatccatac caataccagc actgattgca ataggtgtac gagtcaagaa
    13441 ctcgattgaa ccgaatgagt gcatacgtag gtttacgacg tcagccatag cgaaggcagc
    13501 accttgaaca agtgagtaaa caagatacat aggtgttgcg atgaacatga acatgtattc
    13561 gattggttca gtaacccctg tcaagaatgt tgcaagagct gttgcaatca tcataccttt
    13621 gtatttatgt ttcttgtcag catcaacatt acggtagata gcaacaatca cacccatcaa
    13681 gataccgaat gaaccgatca tttgtccaac tttgaaacga gctggatgta ctgtatctaa
    13741 caagtgttgg tattgactag catcagtacc tttaaggttt acaaggtctg ttacccatgc
    13801 aagccatagt gggtcttgac cgaatacttg agtaccttta gctgcaccag ttaaaatgtc
    13861 ataagtacca ccaagagctg tgtagttcat tgggatagtc aacatgtggt gaagaccaaa
    13921 tggcaagagc aaacgttcca aagtaccata caagaatggt gcaagaattg gagcagtttc
    13981 ttgtgagttg gcaatccaga taccgaagtt attgatacct gtttgaacta ctggccagaa
    14041 agcagcaagt agaattgcag cgattgctga acgaagaata actacaaatg gtacgaaacg
    14101 tttcccgttg aagaatgaaa gtgcatcagg aagtttacgg aagttgtagt atttgttgta
    14161 agcagttgcc cctacaaaac ctgagataat ccctacgaat acccccatgt tcaaggctgg
    14221 agcttcaaga acactgataa agtaatcagc aactttgatt gaaccaccaa agaaagtagt
    14281 taccatagca tctggatttt tcaacatatc gcctgacaca ccaaagattg taccagtgat
    14341 acggttaatc aagataaagg caagaccagc ggcgaaagca ccaccagcac gttctttagc
    14401 ccagcttcct ccaatggcta gggcaaacaa aatgtgaagg ttaccgataa ccccccaacc
    14461 gatttgctca agaattccac ctgtgatgac aagtggtgta aaggttgggt taatcatcac
    14521 gatagactta ccgattgaaa tcatcaaacc agcagccggc ataaccgcga taactaccat
    14581 caaagcctta ccgaattttt gccaaaattc gaaagacaag acatttttga atgtatcttt
    14641 catcattcaa atctccttta tttttattta ggcaaacgtt ttacgaaaac gtttgcacct
    14701 tctatgattt aattatacca ctttaatttt ttttgtaaag gcttttataa aaaaattaca
    14761 cttttttcta aaaaatttct agttgaaagt tctataatga agttagccac cttaccttag
    14821 tcaagaatta gatgtttcac tatgtttgag taagttgatg atttcatttg ataacaggtt
    14881 tgaaactgtt aggctaggtg gccaaggcta atcatagcct tggtttagct gaaaaaacag
    14941 gttcaagggt tcctgttgtc aaatgaaatg tgatttaagg tataagaaaa cacctctgtg
    15001 ctatacttgt tgttcaccac aaacacaagg aaaggcacag agatgcaaga acattatacc
    15061 ccaaaaggga aacatttgac aatagataac cgtcgcttga ttgagcggtg gaagaatgaa
    15121 aataagtcca atcgtgaaat tgcaggcttg ttaggaaagg cgcctcaaac gattcataat
    15181 gaagtcaaaa gaggtacaac tttacaacaa gtgagaaaag ggctatacaa aaaggtctat
    15241 tctgccgatt acgcacaaac tgtttaccaa ttcaatcgaa aacggtcggt gaaaaagtta
    15301 attttaacaa aggaaatcag agagaagatc ttacactatc ataagcaaaa attttcgcct
    15361 gaaatgatgg ttaacaagaa gcaagtgaaa gttggtattt caaccatcta ctactggttt
    15421 cataatggtc atttaggatt gacgaaggcc gacatgcttt atcccagaaa aaggaaaggt
    15481 gtcaagaagc aagctagtcc gaactttaag ccagcaggta aatctatcga agaacgtcct
    15541 gacgttatta atcttcgctt ggaaaatggt cattatgaaa ttgataccgt cctactgact
    15601 aagataaaaa attattgcct gttagtctta accgaccggc ggagcagaca ccaaattata
    15661 aggttaattc caaataaaac tgctgaatct gtcaatcagg cgcttacgtt actattaggg
    15721 gagcatcgta ttctgtccat tactgcagat aatggttcgg agttcaaacg attgtctgag
    15781 gtatttcctg aggaacatat ctactacgca catgcttact cttcatggga gagaggttca
    15841 aatgaaaatc ataatcgatt aattcggaga tggttaccta aaggaaccaa gaaaacgact
    15901 ccgaaagaag tagcttttat cgaaaattgg attaacaact accctaaaaa atgcttggac
    15961 tacaagtcgc caagtgaatt tcttttgggt ggctaacttc aacttgaaat ttgggaaaaa
    16021 tttctagtgc gccaaatttc aagttcaaat tagccatcaa gaagtcttct ctgggggact
    16081 tctttggaag ctcttttctt ctacgcatct cttttcaaaa actcttgtag caaaaaagga
    16141 gattttacaa tctcctcata aaagcagcta ttttacctaa atcttcaaga atcggcgcat
    16201 ggatattcct gatcccaatg aaccaatgaa aaccccaatc acaaatagta gggcaatcat
    16261 caacggacta aataaatctg gactaatcat ggatagattt tgccctacca acgatttgtt
    16321 gacagattgg taaacaattt gataaacaat aaagaccaaa acagatggtg cgatagctcc
    16381 caataaaccg ataaaggctc cttctaacaa gaacggtcca cggatataac tgtttttagc
    16441 tccgaccaag cgcatgattt gaatttcgcg actgcgggaa ataatggtaa tacgaatggt
    16501 atttgaaatc aagaaaactg cgataaaaat taacaaagca gcaatcccta gtccccaaac
    16561 acggataaat gaagctaact tgaagagtct ttctgtattg gcaccgccat cttgaacctc
    16621 agagacacct tcaatttttt tagcatcttc ggctatagtt tttacatcat ttggagcgtt
    16681 tgcctctaca atataggcat catagagagg attggcatct ccttcaaaga ttttccagtt
    16741 atctcccatt atctcggtta atttttcata ttgttcttct ttacttgaaa aggtaacact
    16801 tttaaccgta gacatgttct tcaaagaatc atataccttg tggtagtcat tatttgtaac
    16861 agtttgacct tctttttcaa ttgtctgact attatcttcc acatcctttc ggatataaac
    16921 tactacacgg acattatttt caatatctgt agctagtttc gctgtattga aaataacaga
    16981 tgcaaatatt gccaccaagg tcaaagtaat catgactgaa ctgacagcag ctactgtcat
    17041 ccaaccattt cgtttcaaac tttttaaggc ttcaaataaa tggcgaaaaa atctactaat
    17101 catcgtatcc atactctcct tttgattcgt cacgaacgac acggccattt tcaatggcaa
    17161 tgacacggtg gcgcaaggta tttacaatct ggctattatg agtcgccatc aaaatagttg
    17221 tcccttgtag gttaatccgt tccaagagat tcataatttc ccatgaatta tccggatcca
    17281 gatttcctgt tggctcatca gctatcaata ctttgggatt atttacaatt gcacgcgcaa
    17341 tcgcaatccg ctgttgctcc ccacctgaga gttcatttgg gaaagaacga accttatgct
    17401 tcaatccaac caagtccaaa acttccatca ctcgtttttt gatattacgg cgattttccc
    17461 cgattacttc catagcgtaa gcaatatttt catagacagt tttctttggt aacaatttat
    17521 aatcctggaa gacaacccca acactacgac gtagaagcgg gacatctttc tttttgatct
    17581 taaccagatt aaaaccagca actgataggc ttcctttatc gatttttact tcacgataca
    17641 gagaacgaat aaaagttgac ttccctgctc ctgaaggtcc tacgatgtaa gcaaattccc
    17701 ccggttgaac gctgaccgaa acaccgcgta gagcagtcgt tccgttgtcg tattttttaa
    17761 cgacatctct catttcaata attgacatgt gagttccttt ctatcttagc taattcgcca
    17821 cttgagataa gcatcgataa aaccatctag gtccccatcc ataaccttat ctacctgagc
    17881 aacctcaaag ctagttcggt gatcttttac catagtataa ggcgtgaaga cataagaacg
    17941 gatttggctt ccccaagtga tctccttttt ctcacctttg agagaatcta cctccgcagc
    18001 cttcttatct tgctccattt gatagagctt agcctgcaac atcttcatgg cacgatctct
    18061 atttccatac tgggtacgat ccactgttga ttggacaaca attccagttg gaatgtgggt
    18121 taaacgtaca cctgttgaaa ccttattgac gttttgtcca ccggcaccac ctgaacggaa
    18181 ggtatccatc ttgatatcat cttcacggat ttccacttca atagtatcat ccaattctgg
    18241 catcacttct acagatgtga aagaggtatg gcgacgtttg gcagagtcaa atggtgagat
    18301 tcgcactaag cggtgaacac ccatttctga cttgaggaga ccataggcat taggcccttc
    18361 aaatgataaa gttaccgact taataccagc ctcatcacct gcttggtaat ccaacacttc
    18421 cactttaaag cctttagcat taccataacg agtatacata cgaagcaaca tatcacccca
    18481 gtcctgcgcc tcagtaccac cagaacctgg atggatttcc aagatggcat tgttgtggtc
    18541 ataaggttct gacaagagta gagtcatctc gtagctggtc attatcttat caagttcggc
    18601 taattgcgct accagttcat catgcactga ctcgtcttca gccaaaaaat ccaataaaat
    18661 ttcgacttca tcctgcaact cttccatctt atggaaggta ttgtaagtgt tttttaattc
    18721 attcaattct tgcgacgttt tttgggccgc aatattatcg ttccaaaaat caggttctgt
    18781 catcttgttt tccaagatgg caatctcttc ctctagccct tcgaggtcaa agagaccccc
    18841 tgaaagaagc taatttttca cgatttgcgt caattttctg acgaattact gaaatgtcca
    18901 taaatactcc ttttttacat tatttcatta tagcatattt tatcatttct ttccatcttt
    18961 tgctctaatc cccttttcat gaaaaaagaa gcctttggac ttcccttctt acaagacttt
    19021 tgctgaagtg cgagcgattt cttccacttg aataccattt gcttcaaatt tttctttcaa
    19081 ggctggtaaa tcaattgatt catcgatttg cacttcgata atcaccttac catccttacg
    19141 cggaatattg actgtatggg agatattcaa attttcttct acaatcaaag aaacaatttt
    19201 tccaagaaca ccaacttcat cttctgtaac aaagcgtaca cgaatccctt cttcgccata
    19261 acctgcaatt tcaagaaagg cttggaaaac atcacggtca gtaataactc cgtatacttg
    19321 atggttatct acgacaggga gaataccaat cttatttttc aacatcagat aagttgcatc
    19381 ttctagacta gcatagcctg agacagtgac aacatcgcga atcatgacat cttttacttt
    19441 tgtcttattc agaagataat tcatctcata gatagaaaga cttgttgctt tagatggact
    19501 tgcttgtgca atggttccct cagtcaccaa accaaccaat tgatcatttt cgataacagg
    19561 caagcggtgc aattcttgct ctctcatcaa atctgctgca tgagatactg ttgtatctgg
    19621 actaatataa actaccttgc gggtcataaa atctttaact gccatgagac ttctcctttt
    19681 ctattcttat ccctattata caatcttttt gcaaatctat caaacgctta catttctttt
    19741 tcaaaattta gaaaagtatg aataagctag caaaaagagc tctaaaatcg agctctgtga
    19801 atgaaggtaa gaaacttttc attcgatttt ttcaattatt agaaattaag ctttcaatgt
    19861 agatgcagat ttgtttgcaa tctcaatcta ccgactaaaa aggtcccccg gactatattg
    19921 atgattactt cgtaatctcc atctgccgac taaaacaatc cactggattg ttttagccac
    19981 ctagatatgc ttttctgact tcttctgatg aagcgagttc ttttcctgtt cctgatagga
    20041 cgattttccc tgtttccagt acatatcctc ggtcagagat tgcaagtgct ttattggcat
    20101 tttgttcaat caagaggacg gttgttcctt gtttctgaat atcttgaatg atatcaaaaa
    20161 tttcttggat aaagattggg gcaagtccca ttgatggttc atctaaaaga agaagttttg
    20221 gtgttgacat gagggcgcgt cccatggcaa gcatttgttg ttccccccct gaaagagtgg
    20281 ctgcatcttg gttcttccgt tcttcaagac gaggaaagcg tgagaaaacc ttcttcaagt
    20341 tagcttgatt ttcttcacga tttttcttta agaaagctcc catttcaaga ttttccataa
    20401 cagtcaagcc aggaaagacg tggcgtcctt ctggaacttg tgaaagacca cctgccacga
    20461 ttttctgagc tggcattttt tggatttctt gacctaaaaa ttcaatcttt cctgaacttg
    20521 gtcgaaccaa acctgacaag gtgcgaagaa tagttgtctt acctgcaccg ttagcaccga
    20581 taagggaaac aacttctcct tcattaactt caaagcttac atcacggact gcttggatca
    20641 taccgtaatg cacagaaaga ttttcaactt ttaacataga cattaggctt cacctcctag
    20701 ataagcttcg ataacgcgtt tattggtctt aatttcgtct ggagttcctt gagcgattaa
    20761 acggccatat tcaagtacgt agatacgttc tgttacttcc atgaccagat tcatatcgtg
    20821 ttcaatcaac atgattgtaa tcttaaactc atctttgata cgacgaatta actcagtcaa
    20881 ttcggctgtt tcctgtgggt tcatacctgc tgctggttca tctaagaaga gaattttagg
    20941 ttccgtagca agggcacgaa caatttccaa acgacgttgt tgtccgtagg aaagattttt
    21001 agcaagagtc tctgcatcac catctaaatc aaagattttc aacaattcca aagctttagc
    21061 ctttaattct ttttcactct tgtaaaaagc tggtaagcgt aagaaactag taaaaacatg
    21121 ctgtttgtga tggtttccaa aagcaatcaa aacattgtct aaaactgtta aatctttaaa
    21181 aagacggata ttttggaaag tacgtccaag tcccaaagag gcaatcttat aaggtgattt
    21241 cccattcaaa aggtgaccat ctagggttac tgttccctcg cttggttcat aaacaccggt
    21301 caaaaggttg aaaagggtgg ttttcccagc tccgtttgga ccgattaatc caaccagttc
    21361 cccttcgttc aattcaagag tcacatctcc aacagctgtt agaccaccaa aatgtttggt
    21421 taactgtttt acttcaagta atgccattag ttttgttcct ccttcttaga ttttttaaag
    21481 aaacgtgata ggctcagttc ccacgttcca aggagtccac ctggtctgaa aatcattacc
    21541 aataccaagg ccaaagcgta aataatcata cgcacactag caacatcttg gagaagcata
    21601 ttcaaaattc ccagaacaat agccgaaaca atcgcacctg taatggaacc gagtccacca
    21661 aatacaacaa taatcaaaac gttgattgag ttgatgaagg tgtaatcttt cggtacaaca
    21721 gacccgataa atcctgcctg aagtgaccca gcaatacttg cagtaatggc accaaagaca
    21781 aaagcgatga ttttaatttt agtcgtatta accccaactg actcagcagc gatttcatct
    21841 tcacgaacag agagggttga acggccaatt gggctacgca agaagttcaa ggttgcaatg
    21901 gttgtaatca cgacaaagaa gtaaaccatt tgccaagttg taaagttagg aatccctaag
    21961 atacctgccg caccatttgt aagacttcca ccattgatga taaagatacg gataatttca
    22021 gaaacaccca gagttgctac cgcaagatag tcccccttca agcgcaaggt tggaatgccg
    22081 acaagtaagg caactgctcc tgaaagcaaa gcccctacaa gcatagctcc aaagaaggca
    22141 ccgtaggttg gtgatttaga accaataata gctgctgcat aggcaccaat cgccatgaaa
    22201 ccagcatgac caagtgaaaa ttgtcctgaa aaaccaacga ttaagttgag accaacagcc
    22261 aaaataatat taattccaat ttgttgtaaa atctgtacat agaatagatt aagtactccg
    22321 actgaaacca gtacactaat caagctatag ccagctaaca aaaggagtaa ccatagaata
    22381 ttaactttta aattttcctt catcgtttac accttctctt tcacattctt accaaggata
    22441 ccagctgggc ggacaatcaa gatcaacaac aagattccat aaacaatggc atcacggaaa
    22501 tctgacatcc caaaggctgt cgcaaaggtt tccaatagac caatcacaaa gccaccaaga
    22561 gccgcaccag gaataattcc gataccacca agtactgcgg caacgaaaga tttaagacct
    22621 ggagtaaccc ccatcaaagg ctcaagagag ttataataaa gagcaatcag aacaccagcc
    22681 gcacccgcaa gagcagaacc caaagcgaag gtaaagctaa tcgtacggtt tacattgatc
    22741 cccatcaatt gtgccgcgtc gctatctact gatactgcac gcatggcttt ccccatctta
    22801 gtcttttgga caatgacttg taacaaaatc atcaaaatca aggaaatggc caaaatcatt
    22861 aactgcacat ttgttaagct aattggtccc aaatcatatc gaactgtttg aatcgcttga
    22921 gggaaggcac gggtattggc accaaccaga tagaccattc catactccaa taggaaagaa
    22981 accccaatag ccgtaatcaa aacagcaata cgagtagagt ggcgcaaagg tcggtaagca
    23041 agaaactcaa tcacgacacc aagaatagct gtcgctagca tagctacaat aagcgctaca
    23101 aagaaattca tttggaaaga attgatcaag aaataaccga taaaggctcc catcatataa
    23161 atatcaccat gggcgaagtt gatgagcttg ataattccgt aaaccatggt atatcctagg
    23221 gctaacagcg cgtaaacact acctagaatc aaaccattta cgagttgttg gagcataaga
    23281 ttcactcttt ctatttataa ttccgagggt tttccctcac tttttgatag gttcttatac
    23341 tcaatgaaaa tcaaagagca aactaggaaa ctagccgcag gttgctcaaa gcactgcttt
    23401 gaggttgtag ataagactga cgaagtcagt cacatatata atccaaggcg acgttgacgc
    23461 agtttgaaga gattttcgaa gagtattaaa tatcgaaaca gggagtgagt caaaggctca
    23521 ttccctattt caacattttt ctattatggt tttacaactt ctgctgcttc aactttacca
    23581 ttgttcatgg tcatcatgta agcagttttg actgtgttgt ggtctgcatc gaagcttgtt
    23641 tgaccagtta caccttcaaa atcttttgtt ttagcaaggt tatccttgat ttcacctgaa
    23701 tttttagcac cttttgctgc gtttgctaca aggtgaactg aatcataagc caaggctgca
    23761 aatgttgaag gctcttcatt gtacttagca cggtaagcgt caaggaaggc tttagcttta
    23821 gctgaaactt ctacagtagt tgagaagcct gagataaagt agatgtttga tgctttttca
    23881 gcagttgctt gttgtacaaa ctcctcaccg ttgaatccat caccaccaac gattggtttg
    23941 tcaattccca tgccacgcgc ttggtttaca attttaccag cctcattata gtaaccagga
    24001 acaacgatag catcaaagtc tttccctttc atttttgtaa gggctgcttg gaagtctgtg
    24061 tcacctgcta cgaaagtttc atctgcaacg atttcaccct tgtatgactc gcggaaagat
    24121 ttggcaatcc ctttagcata gtcactggca ttgtcagtgt aaagaacaac tttcttagca
    24181 tttaattttt cagaaacata gtttgagata atttttcctt ggaagctatc ttggaaagtt
    24241 ccaataaaga ggtaatcttg acctttagtc aatccatctt gagtcgcact tggtgagatc
    24301 aatggaacac ctgcttttgt agcgttcgct accgcagctg cagtcgcacc agatgtcgca
    24361 ggtcctacga ctgctgatac tttagattgg gttacaaggt tagttgtaac tgaagcagcc
    24421 tcagctgttt cagacttatt atctttatcg actacttcga tttgttttcc atcgatacca
    24481 cctgcggcat tgatttcatc aacagccaat tgggcacctt tttgttcagc tgttccgtat
    24541 gcagctaaag aacctgattc ttcaaagtta aacccgattt taattgtctt ttcctctact
    24601 gagttaccag cagtgttgac tgctccagac ttcacttctc cacaggctgc aagaagtgct
    24661 acacttgcaa gcgccacaaa cgatagggca aattttttct tcatcttttt tgtctcctta
    24721 tttcttaaat agtctgttaa gaatataccg aattatcaga aaattgtcaa tgttttcctt
    24781 gaactttttc gatgataacg ttttcctatc gataaagatt gcccacaaag ggtgtttcca
    24841 actcttggat atgacaaacc ctaacttttt taataaattt ttccttgctc aagcgtccga
    24901 ccaattgctc cacttcttga gttggaacat agagttgtaa gtaacgatgt ttcttggaat
    24961 gataggtaat atctccataa tcctgcagtt ttttggcatc acgattatag taaagataga
    25021 taatcaagcc agagcgattg actttttcaa acatgataaa tcctctttct aagaaatctc
    25081 tccctattat accaaaaaaa gcaaacccag tcgagtttgc cttctatcat cattagttca
    25141 atgaattgtt ggccataatt tcatcaataa agccatattc aagtgtttcc tgggcgctca
    25201 tccagttatc acgttctgca tctgcatgga ctttttccat tgactgacct gaattttcag
    25261 ccaagatttt ttccaaggta ttacgagttt tgagcaagtg ttctgcagcg atagccatat
    25321 cagtttgttg ggtaccacca cctgtaccgc ccattggttg gtgaatcatg tattcagcat
    25381 ttggaagcat gaaacgtttg ccttttgctc cacttgatgc gatgactgtt cccatagatg
    25441 cagccattcc cataacaatg gtttggacat ctgccttgat aaagttcatg gtatctacga
    25501 ttgccaaacc agctgaaaca gaaccacctg gtgtattgac ataaaggtaa atatcttttg
    25561 tactatcttg ggcatccaag aaaagcaatt gggcaataac agagttagcc atattgtctt
    25621 caaccggacc tgtcagcata atgatgcggt ctttgagaag acgtgagtaa atatcgtaag
    25681 aacgttctcc acggcttgtt tgttcaataa ctacaggaat cattcatttc tccttttgag
    25741 ttttaatttt gttggtcaaa tgactgaaga taagactatt ataatatctt ggtcaaaaaa
    25801 ggtcaaattt ttgctctgct ttcattagac agaaacaaaa acccaacctc ctttcgtgac
    25861 tggaaatact tttccaagtc attcttcttt tcgatcttat tttgtaccga acaagcggtc
    25921 tccagcatct ccaagacctg gaacgatata accgtgttcg ttcaaacgtt catccaaggc
    25981 tgctgtaaag atttctacat ctggatgagc ttcttgaagg gcttttacac cctctggagc
    26041 agatacaagg cagacaaatt tgatatttga tgcgccacgt tttttaagag aatcaacagc
    26101 caagattgct gagccacctg ttgccaacat tgggtctact acaaaaattt gacgttggtc
    26161 aatgtcctca ggcaatttca ccaagtattc aactggttga agtgtttctt catcacggta
    26221 cataccgatg tggccaactt tagcagctgg aaccaagctc aagagaccat caaccatccc
    26281 gatacctgca cgcaagattg ggacgatggc caatttctta cctgccaatt gtttttgaac
    26341 tgtttttgta attggtgttt cgatttccac atcttctagt ggaagatcac gaagtacttc
    26401 ataccccatc aacattgcaa tctcatctac tagctcacga aaagcttttg tagaagtatc
    26461 tgtacgacgc aaaattgaca atttgtgttg aatcagtggg tgattaataa cttcaatttt
    26521 tcccattttt ggaattcctt ctttcaattt attcttctta ttataccaaa aaacggttta
    26581 aaaatctttc taaaccattt atttttgata atttttacat tagatcagcc tctttaagag
    26641 ctgtctgtac tgtctcaagt ggtaaatggg tcaattctgt ccctttttct tgataaaggt
    26701 attgggcgta gtcgtccatt cggtactggt tgatataaac cacgcgcttg cagccgacct
    26761 gaagcaattg ttttgtacag ttgagacaag gaaaatgggt tacataggct gtaaagcctt
    26821 tgggaacacc acgctcagca ccttgaagga tagcattgac ctcagcgtga agggtgcgaa
    26881 cgcagtggcc ttcaatgacc aaacattcgt gatcaataca atgctcagtc cctgacaccg
    26941 aaccattgta accagtggaa ataaccttat tatcttttac cagaatcgcg cccactttag
    27001 cacgtttaca agtggaacga ttcgcaatta gtagagcttg ggctgcaaaa tactcatccc
    27061 aggccagtct tttttcagtc atctcttttc tcctttttct ctatttttta aaaaatggta
    27121 aacctaaatc tgcaatcttt tcagctggta ccttcatgcc atccttgatc cattttagaa
    27181 ggacagagac gatggctgag ctccagaagg aatgaagata agagctgaca ccttttgatt
    27241 tcccatggta tttttctaga aattcctgca tggcttggac aaagattttt tccagatggt
    27301 aatccaaggc caattgaatt actctagctt cctttctggc ctcccggaaa aggtgaaccc
    27361 aaaccaaata aaggtctgtc tttaaatcgt aatgatgcag ctgttccata atattgtgga
    27421 cagttcgttt aaagacgctc tctaaaattt cctctttgga gtcataattg cgataaaagg
    27481 ccgcacgcga aacacctgca cgtttgacca attcagaaat actaatcttg gtcagttcct
    27541 ttttttccaa gagttgcaag agggctgttt caatggcttc tctggttaat aaattggatt
    27601 cttggtttga ttttctgaga ttttcaagag acttttcaga gattctacgt tcagacataa
    27661 cattttcttt ctacttgtca caacagacgg atgatgcttt tgtttcaagg gttttcatga
    27721 tataattgta aaaaaagaca gaacctttgt caatgtataa ctgacaaaga tggagaattt
    27781 ctatgacttg gaagattatt gctgactctg gttgtgatta tcgtcaactg ccaacaccag
    27841 ctattaacac aacctttgta agtgtcccct taaccattca agtagctgat caggtctttg
    27901 ttgatgacgc cagtctcgat attgaccaaa tgatggaaac catgtatgca actgcagaag
    27961 cttcaaaatc ggcttgtcca agcccagatg actatttgcg agcatttgaa ggtgccaaaa
    28021 acattttcct agtaaccatc acaggtaccc tttctggcag tcacaatagt gctcaactag
    28081 caaagaatat ttatctggaa gaccatcctg acactaagat tcatgtgatt gatagtttat
    28141 ctgctggtgg tgaagttgac ctactcgtag aaaaattgaa tgacttgatt gaccagggct
    28201 tgtcttttga agaagtggtt gaagctatca ccgcctatca agaaaaaact aagttgctct
    28261 ttgtcctagc caaagtcgat aacttggtga agaacggccg tttgagcaag cttatcggta
    28321 cggtcgttgg ccttctcaac attcgtatgg tcggaaaagc tagtgaaact gggactctcg
    28381 aattgctaca aaaagcaagg ggatcaaaga aatcagttca agctgcctat gatgagttag
    28441 taaaagctgg atatgctggt ggccgtattg tcatggccca acgcaataac gaaaaatgtt
    28501 gtcaacagct ctcagagcga atccgtgaaa ccttcccaca agcggatatt aaaattctac
    28561 caacctctgg tctctgcagt ttctatgcag aagagggcgg tttgctgatg ggctatgaaa
    28621 ttgattaatt gcattcttga caagaggtga ccatcatctc ttgttttttt gtggtacaat
    28681 agagctatga aacattttga tactattgtc atcggtgggg gacctgctgg tatgatggct
    28741 acgatttcca gtagctttta tggacagaaa accctcctca tcgaaaaaaa tcggaaactt
    28801 ggaaaaaaat tagctgggac tggtggggga cgttgcaatg tgaccaacaa tggtagctta
    28861 gacaacctgc tagctggaat tcctggaaac ggacgctttc tttacagtgt tttctcccag
    28921 ttcgataatc atgacatcat caactttttt acagaaaatg gtgttaaact taaggtcgaa
    28981 gaccacggac gcgtctttcc agccagtgac aagtctcgga ctattatcga agctttggaa
    29041 aagaaaatca ctgaactagg tggtcaagtt gctactcaaa tagaaatcgt ttctgttaaa
    29101 aaagtagatg accagtttgt ccttaagtca gcggatcaaa ccttcacttg tgagaaactc
    29161 attgtcacaa caggtggtaa gtcttatcct tcgactggtt cgactggttt tggtcacgag
    29221 attgctcgcc attttaagca taccatcacc gatcttgagg ctgctgaaag tcctttatta
    29281 acagattttc cacataaagc cttacaaggg atttctctgg acgatgtgac cctaagttat
    29341 ggtaagcatg tcatcactca tgatttactc tttacccact ttggtttgtc aggtcctgct
    29401 gccctacgca tgtctagctt tgtcaaaggt ggggaggttc tctcactcga tgttttgcct
    29461 caactttctg agaaggactt ggttacattt ctagaagaaa atcgggaaaa atccttgaaa
    29521 aacgctttaa aaaccttgtt accagaacgc ttggccgaat tttttgtaca aggatatcct
    29581 gaaaaagtca aacagctgac tgaaaaggaa cgagaacaac ttgtccagtc cattaaagaa
    29641 cttaaaattc ctgtaactgg aaaaatgtcc cttgcaaagt cctttgttac caagggtgga
    29701 gtcagtctca aggaaatcaa tcctaaaacc cttgaaagta agctggtacc tggcctccac
    29761 tttgcaggcg aagttatgga tatcaatgcc cacacgggtg gctttaacat cacttctgcc
    29821 ctctgtaccg gctgggtggc gggaagtctg cattatgatt aaagattaaa ggttgtgaag
    29881 aatgaacaga agagaggcag tcgaatttgt taacatgtgt atgattaaaa acggagataa
    29941 gatcctggtc caagaccgag ttagtcccga ctggcctggc attacttttc ctggtgatca
    30001 tgttgaacgt ggcgaatcct ttgtcgatgc tgtcattcgt gaagtgaaag aagaaactgg
    30061 tctgatcatt tccaaacccc aactctgtgg tatcaaaaac tggtatgacg acaaggatta
    30121 tcgttatgtc gtcctttttt acaagacaga acactttact ggtgaactcc agtcttcaga
    30181 cgaagggaaa gtttggtggg aggactttga aaatctttct catctaaaac ttgcaaccga
    30241 tgatatgtct gatatgcttc gtgtgtttct agaagaagat ctcagtgaat tcttttacta
    30301 caaaaacggt gacgactggc tttatgattt gaaataaaaa ataggctagg aaattcctag
    30361 cctatttatt ctgcatttgt ctgaacgtaa gccgcaatgg catctgacgt gtactgggct
    30421 gtttcagaac caaacttgtc aatgttttcc ttaaactctg ggttgtagac gtaaccttta
    30481 ccgatatgac cgaatacctc aatagagcag tcaaatccat aagtgcgaat agcttgcaag
    30541 agcttggctg cttgctcttg gttttcggtt gctgttgcag gtaaaccaac ttgaagattt
    30601 tgtgccaaag tttgaaagac ttggttaaag gcggccgtag cctcgtcttc gtgacctttt
    30661 tggcgttcga gcgcttgtcc catgacttct tgaccatatt tctctaccgc ttcttggtgg
    30721 tatttttgat tgtcttgata gctaaatccc gtgaattttt cctcaatggt catttttctt
    30781 tctccttttt gttcttgaat agttttttgc aaggtggaaa tcaaggtatc cagatgttgc
    30841 ctttcgcgag ttagatagtc caactgccta gtcaaatggg gcaataaatc tgtcctttct
    30901 tcctttaaca gctctgctat tttctctaaa gaaaagccta gatatttgta gtaaagaatg
    30961 acctgaaggc gttccaaatc ctcttgacta taggttcgat agccgttttc cgactttaag
    31021 gggaccaaga gtcctatctt gtcatagtga tgcagggtct tgacagagac acctgaaagc
    31081 tgcgcagctt cttttatatg gtacatgatt tcctccttac aatgatagta taacccctcc
    31141 ccttaggtca gagtcaagcg tttttgagaa aggtgtgaaa acttgaaaat ggttttcttg
    31201 acagacctta gaaaacataa taggatagtc aagtctatca atcaaacaga aggctatttg
    31261 acaactcaag tagctttttc ttattttgaa aaaggagatc agagtttaac tatgtcagaa
    31321 aaatcacaat gggggtcgaa acttggcttt attctagcat ctgctggctc ggtcatcggg
    31381 cttggttccg tttggaagtt tccctacatg actgctgcta atggcggtgg aggcttttta
    31441 ctaatctttc tcatttccac tattttaatc ggtttccctc tcctgctggc tgagtttgcc
    31501 cttggccgta gtgctggcgt ttccgctatc aaaacctttg gaaaactggg caagaataac
    31561 aagtacaact ttatcggttg gattggcgcc tttgccctct ttatcctctt atctttttac
    31621 agtgttatcg gaggatggat tctagtctat ctaggtattg agtttgggaa attgttccaa
    31681 cttggtggaa cgggtgatta tgctcagtta tttacttcaa tcatttcaaa tccagccatt
    31741 gacctaggag ctcaagcagc ctttatctta ttaaatatct ttattgtatc acgtggggtt
    31801 caaaaaggga ttgaaagagc ttcgaaagtc atgatgcccc tgctctttat catctttgtt
    31861 gttatcatcg gtcgctctct cagtttgcca aatgccatgg aaggggttct ttacttcctc
    31921 aaaccagact tttcaaaact gactagcgct ggtctcctct atgctctggg acaatctttc
    31981 tttgccctct cactaggggt tacagtcatg ttgacatatg cttcttactt ggacaagaaa
    32041 accaatctag tccagtcagg aatctccatc gtagccatga atatctcgat atccatcatg
    32101 gcaggtctag ccattttcca agctcggtcc cccttcaata tccagtctga agggggatcg
    32161 agcttgctct ttatcgtctt gcctcaactc tttgacaaga tgccttttgg aaccattttc
    32221 tacgtcctct tcctctttgc gactgtcact tcttctgtcg tgatgctgga gatcaatgtg
    32281 ggcaatatca ccaaccagga taacagcaaa cgtgccaaat ggagtgttat tttaggaatt
    32341 ttgacctttg tctttggcat tccttcagcc ctatcttacg gtgtcatggc ggatgttcac
    32401 atttttggta agaccttctt tgacgctatg gacttcttgg tttccaatct cctcatgcca
    32461 tttgaagctc tctacctttc actttttaca ggctatatct ttaaaaaggc tcttgcaatg
    32521 gaggaactcc atctcgatga aagagcatgg aaacaaggac tgttccaagt ctggctcttc
    32581 cttcttcgtt tcttcgtttc gtcattccaa tcatcatcat tgtggtcttc attgcccaat
    32641 ttatgtaatc aaaaaggact tgagtagtaa actcaggccc tttcttttta tggatggcta
    32701 acaatcaatt ccaaaccttg cccttccaga gtccaagctt caacatcact tggtaggata
    32761 aagtggctac ctttttgaat tggataattt ttcccgtcaa caattagctg accttgacca
    32821 gctaagacac tcaataagct gtagtcagct gtcttttcaa agtcaacttt tccagtaatt
    32881 tcccacttgt aaactgcgaa gaaatcatta gatacaagga gagtggaacg caaatcatct
    32941 gctttaacag ttacaggacg gctatttgct ggctcaccaa tgttcaagac atcgatggat
    33001 ttttcaagat gaagttcacg caagttgcct ttgtcatcct tgcggtcaaa gtcatagacg
    33061 cgataggtgg tatcgctaga ctgctgggtt tcaaggatta agatacccgc cccgatagcg
    33121 tgcatagtcc cgcttggtac atagaagaaa tctccagcct taacagggac tttggtcaac
    33181 aagtcatccc agttcttgtc ctcgatttgc tggcggagtt cttcttttga cttggcattg
    33241 tgaccgtaga taatctctga accttcatcc gctgcgataa tgtaccagca ttctgttttt
    33301 ccgagttcgc cttcatgctc gagtccataa gcatcgtctg ggtgaacttg gacactgagc
    33361 cagtcgttgg catcgaggat cttggtcaaa agtggaaata caggttctgg acgattgcca
    33421 aataattcac ggtgttccgc atacaaagta gcaagatctg ttccctcgta acgaccattg
    33481 gcaactttag agactccatt tggatgggct gagatggccc aatattctcc gattttttca
    33541 cttgggatgt cgtagccaaa ctcatcacgt agcttggctc caccccagat tttttcttgc
    33601 ataactgatt gtaaaaataa tggttctgac atgtcgatct cctgtctgat ttttctcccc
    33661 tcattatagc aaaaaaagag ttcgaattga actctttttt acatcttata aagcagggag
    33721 aagattttat aaaaatagta aacaaatgtg ctctactcga tgcttacacc attgctataa
    33781 atgacatgta ccaatagaag gacttcttct tgctacgttt gagagtccca tttcctacat
    33841 tatctcgatc tacatagata aagccatagc gcttattcat ttcccctgtg ccagctgaaa
    33901 ccgaatcgat acagccccat gtcgtataac caagcaagtc aaccccgtct ttgtaaatgg
    33961 catctcgcat ggccttgatg tgggcctcta agtaagtaat ccgatagtca tctgctacat
    34021 aaccattctc atccggtgta tccatagcac cgagtccatt ttctacgata atactaaact
    34081 aaaatcaaaa agcattatac aatagtgata tgaaatcaac taaagaagaa atccaaacca
    34141 tcaaaacact ctcgtacagc taaatatcat aaacgccttc aaatcgttct atagtaaaac
    34201 gaaacaagaa cagggcaaat cgatcaggac agtcaaatcg atttctaaca atgttttaga
    34261 agtagaggtg tactattcta gtttcaatct actatatttt gtctgatggg caaatcttat
    34321 aaagagatta tagagctttt agactgtaat caaacaacga tttagcgaaa tgtaaaaaaa
    34381 tatgaggagt tcggactcga ctctctcctt caagaaacac gtggtggtcg taaccatgca
    34441 tatatgacag ttgaggaaga gaaagccttt cttgcccgtc atttgaaggc tacagaggca
    34501 ggagaatttg ttacaattga tgccttattt caggcttata aaaaggagtt aggtcgttcc
    34561 tacacacgtg atgccttcta tcaactgttg aagcgccatg gttggcgaaa tattacacca
    34621 cgtccagaac atcctaggaa agcagacgct caaaccattg tcgcatctaa aaataaaatc
    34681 tcaattcaag aagacaagaa agcgctttaa aaccagtaga cgttttcgta aggttcgctt
    34741 gatgtaccaa gatgaggctg gtttcggtag aatcagtaaa ctgggatctt gttgggctcc
    34801 aataggagta ggtccacata tccatagtca ctatatacga gaatttcgct attgttatgg
    34861 agctgttgat gcccatacag gcgcatcagt tttcttaata gctggtggat gtaatactga
    34921 gtggatgaac gtctttttag aagagctttc acaagcttat ccagatgatt attttttact
    34981 cgttatggac aatgctatat ggcataaatc aagtatctta aagattccga ctaatattgg
    35041 ctttgcattt attcctccat acacaccaga gatgaactcc attgaacaag tgtggaaaga
    35101 gattcgtaaa cgtggattta agaataaagc ctttcgaact ttggaagatg tcatgaatca
    35161 actccaagat gtcatataag aactggagaa ggaggtgata aagtccattg ttaatcggaa
    35221 atggactaga atgctttttg aaagcagatg agtattatat gcaatttctt tatataaaaa
    35281 gaccggattg ctccgatctt tcaatagttc atattctcaa tttctatttt aaaaatagct
    35341 aaggttaacg tcaaatgact acacgaccta tttcatacga taaaaatcaa gcactagacc
    35401 agcaggtcct tgaactaata aggactctgt tccccaatcg gttacagttg gtccgtgtaa
    35461 aacctttata ccaagctcgt tcaaccgttt gtagttctgg tctacatcct caacctcgat
    35521 atgaataatg attcctgact gaaagttttc caaaggaacc aaatgatttt gtgacaacat
    35581 aaggcagtga ctaccaatcg taaactgagc aaaaccatca tcagcataat ctgccttttt
    35641 atccaaaata tgctccaagt cagcacagac ttggggaaca tttgaaacga taatatctaa
    35701 ttgatttaaa ttcatttact ctcctccata aaaagaccgg attgctccga tcttttaaag
    35761 ttctgctcta tgaaaatcaa agaataaagt ctacaagttt catatttgat tttcggcgag
    35821 aggaattatt taattgcgcg tgattgcaat ccttcttctt ccaagaagag acggaatggt
    35881 acgagttctt ctgcttcgta tttttccttg aaggctttga tagcttcttc tgagtgaagt
    35941 tttggatcca attcaagtac ttctactgga agtggacggt gttgagtgat gcgagcatcg
    36001 atgacaacag ttttaccttc tttgttcaat ttaacagctt ctgcaacaac tgcatcgatg
    36061 tcttcgatac ggtcaactgt gaatccaaca gctccttgag cttccgcaat tttagcgtag
    36121 tcagcgtttg tgaagtctac accaaacaag tgtttgtttg tatcttcgta tttgttcttg
    36181 atgaagccgt actcagcatt tgagaagaca aggttgataa ctggaaggtc gtattgaacg
    36241 tttgtgataa cgtctgggta gcacatgttg aatgctccgt cacccatgat gttccatact
    36301 tggcgatctg gattgtcttt cttagcagcg ataccaccag gaagggcaat acccattgtc
    36361 gcaaagagtg gagatgtacg ccacatgttc ttaggtgtca tgtgaaggtg acgagtagat
    36421 gtttgagtag tgttacctac gtcgattgag tagatagcgt cttgatcagc atgtttgttg
    36481 attgcattgt aaacttgata caattgcaat tcaccctcag ttttaccttc gagtttgttc
    36541 atgtaatcac gccagttttg gttgttctta acgtttgcac gccaccatgg agttgattca
    36601 actgggttta ctttgtcaag gatagcttta gctgcttgac cagcatcacc aaggattgaa
    36661 gcgtcaaggg catgacgttt accaagtttg taagggtcga tatcgacttg gatgaatttt
    36721 tcagtgttct tgaatgcttc gtaaacttca gcaaatggga agtttgaacc aaggaaaaga
    36781 actgtgtctg cttcaaagac cacttcgttg gctggtttcc aaccaacacg ataagcagaa
    36841 cctgtcaaac cttcatagtt ccattcgaaa gcttcaaagt ttttaccagt tgtgatgatt
    36901 ggtgctttga ttttacgtga caattcagta atcacttcac cagctttaac accaccaaat
    36961 ccagcataga taactgggcg ttcagcattg ttcaagattt caacagcttt gtcgatttca
    37021 acttcgttca aagcaggagc gatgaatgag cgttcgtatg aacctgaacc gtagtatgag
    37081 ttttcgtcga tttcttggaa accgaagttt actggaattt caacaacagc tggacctttt
    37141 ttagaaattg cagcacggca ggcttcgtca attacttttg gcaattgctc agcgtaagct
    37201 acacgtttgt tgtaaacagc gataccgttg tacattgggt tttggttaaa ctcttggaaa
    37261 gcatccatgt tcaattcgtt aactggacgt gatccaagga tcgctaggaa tggagtgtta
    37321 tccatagctg catcgtaaac accgttaatc aagtgagtcg cacctggacc acctgaacca
    37381 actgcaaccc cgattgagcc gccgaattta gcttgcataa ccgctgcaag agcacctgtc
    37441 tcttcgtggc gaacttgtaa gaagcggata tctttgtctt cagccaaagc gtccatcaat
    37501 gagctgagtg ttcctgatgg gataccgtag attgtatcta cgccccatgt tttcaatacg
    37561 ttaagcattg ctgcagatgc agtaattttc ccttgagtca taatgataac tctccttcaa
    37621 tttttttaga tttggagaat acgattacat agaattggaa acgttctcca aatttttact
    37681 attccactgt atcatattta tgctgacttt tctaaaaatc tgctcaaaac tctctattct
    37741 ctattctaat acagttttga aagttctgtc atttctgttt tataacaaag aaatctagtc
    37801 attactttta gtctatttta ctaaaattta acagaaggga actggtcaga acagatacag
    37861 aactaaaggc catggctaga cctgccaatt ctgggttgag agccagtcca acacctgaaa
    37921 agactcctgc tgcaatcgga attccgacaa cattgtagat aaaagcccag aaaagattga
    37981 gtagaattcg atgaaaggtt ttcttactca tatcaaaggc acgaaccact cctaaaagat
    38041 tattggttgt caacaccaaa tctgctgact cgatggcgat atctgttcca gctcccatag
    38101 caatccccac atctgctaca ctaagggcag gagcgtcatt gataccgtcc ccaacaaagg
    38161 ctactttccc tgactgttgc agtttatgga tttcacgggc tttttcttct ggcaagacgc
    38221 ctgcaatgac ctcttcaatt ccgatttgat ctgcaatagc acgcgccaca ccagcattgt
    38281 ctcctgtcag catgactgtt cggagaccac gtttttttag ctgactgatg gctagcttag
    38341 cattttcctt aggaatatct tgcaaagcaa gcaagccttt gatttcattg tcaacagcta
    38401 agaacacaac tgtcttagct tctttttcta gttcttctag tttatcttga taagtattag
    38461 aaatatccat accatccagc attttagcat ttccaagtaa aacttgtttt ccattgattc
    38521 gccctgaaac acctttcccg tgcaaggact gaaaattttc aacagtttga aactcaagtc
    38581 cagcttcact cgctcgctta acgatagcct cagccagtgg gtgttgagaa gcatcttcca
    38641 aggaggctgc caatccaaac acttctactt cgtcgccgat gatatctgtt accacaggtt
    38701 tcccttccgt caaagtcccg gtcttatcaa agacaagagt ttgaactttc tggatttcct
    38761 gtaagacagt tccatttttg aggagaaccc ccatcttggc actacgtcct gtccccacca
    38821 taagggctgt cggtgttgca agtcccaagg cacaaggaca ggcgataatc aaaaccgcca
    38881 ctccgtagag aagagaggac acaaagctag ctccaagcac gaccacacta tccctgagca
    38941 agacgaacca aacccaaaag gtcatgattc ctaaaatgac aactactggg acaaaaatcc
    39001 ctgaaatctt atccgtcaag tcctgaatcg gcgcacgact tgtctgagct ttcttcacaa
    39061 aatccacaat ctgagccaaa acagtctctg agccaacttt ttctgctcta aagacaagcg
    39121 ttccactatg attgatggtt gagccaatga cagtatctcc aactgtcttg tccacaggca
    39181 gactctcacc tgtcaccatg gattcgtcaa tactagagac accttctact acgacaccat
    39241 caacagcaat cttttcaccg ggacgcactc gaatcaggtc gcctaccttg acttgttcca
    39301 aaggaacttg gacataacta tcatcactca agacttctgc ggttttagct tgcaagtcca
    39361 gtaatttctc cacagcttgg gacgtatttt ttctcatttt ttcctcaaaa actgctccca
    39421 aaagaacgaa aaagaggata aatccagcac tttcgaagta aacagggaga ccagcaaaga
    39481 gagcaactag gctatagaaa taagccacta gagttcccag cgcaaccaag gtatccatgt
    39541 tggcattgtg ctttttaaaa ctggcccaag cactctggat atatggctta cctgcaacta
    39601 acataatagg cgttgttgct agaaaggttc cccaatgcat gacttgatga ctaatgctac
    39661 ctgtcaacat cccaatcatg agaatcacaa gaggcacagt aaagatacta gtaatccaaa
    39721 aacgttgcag gagagataga gattttcgag tcttctcaac gactatatag cttccctttt
    39781 gcatcttcat gccacaagaa aattcatgtc gccctaattc ttgaggtgta aaacgaatga
    39841 ctttctcctc atctacgccg attggttcca agataccttc ttcttcaaac agaatttcct
    39901 tataacagtt tgaaggagta gcacgatgaa aggtaatctc agctggaatt cccttttgaa
    39961 gctggatatg ggctggatga tagccttttt cagctcggat acggattttt tgaatgccat
    40021 tttctaagct tgctttcaca atttctgtca tagtctccac ctactctaca atcatcttgc
    40081 cgtgcatcat gttcatacca caagcaaagc caaactctcc aacctgctca ggcgtgattt
    40141 ccactacata ctcttccccc attggcaggt tcgcatgtac accaaaatct ggaaaaacaa
    40201 tttgatccag acatggtgaa ggatccttgc ggtcaaagac aatgcgtgct ggcactgatt
    40261 tcttgaggac aatcaactca ggagtatagc ctcccatgac ttccactcga atctcttggt
    40321 atccgttttt ttgctgggct ttttgtccag atttttcagg ctttttgaaa aaccaaaaca
    40381 agataaacgc gataagggca atacaaataa tggttacaat actatttaac atgacgtctc
    40441 ctttacatac aattacatct tacttctgtt acagcacttg atttcttctc tgaaatcaca
    40501 gcttccaagt cttccaagtc agtctgagta aattcacatt ctacaatcaa gtcagccaac
    40561 aaattcctaa tcctacggga acaaaccttg tctttgatat cttggacaag taaatcccga
    40621 ctttggtcta gagttaaaag ggctgaataa acaaagaact tgccttcttt tttccgagtc
    40681 aaacactctt tctcaaccag acgagccaaa agtgtctgaa cagtggactt ggaccaatca
    40741 aaccgctctg ccaaaaccct aatcaaatct gtactggtct gctccccctg catccaaata
    40801 atcttcatga cctgccattc tgcatctgaa atctgcatta ccatacctcc aaaatctaca
    40861 tttgtcaatt acactcatca gtatactatc aaaatctaca tttgtcaatt atagaaataa
    40921 tattttcttc gaaaaataga attttaatca tttgaaaaac gatttgcagt caaatattac
    40981 tatataaaca ataaaaatat gctatactaa agaaaaaaga aaacaaccac taggggtgcg
    41041 taaagctgag attaacgact gttagatccc tctgactcaa tctaggtaat gctagctgat
    41101 ggaagtggaa atgataatgg ggactagcag tcttctattg cctttctaaa acagactagc
    41161 ttgttcttaa gaatacaaac ttcagttggt tgggaggttt tagatgactt atttacccgt
    41221 tgctttgacc attgcaggga ctgaccctag tggtggtgct ggcattatgg cagatttaaa
    41281 gtcattccaa gcgagagatg cctatggaat ggctgttgta accagtcttg tcgctcaaaa
    41341 taccagaggt gttcagctaa tcgaacacgt ttctcctcaa atgttgaaag cccaattgga
    41401 gagtgtcttt tctgatattc cacctcaggc tgtaaaaact ggaatgttgg ctactactga
    41461 aatcatggaa atcatccaac cctatcttaa aaaactggat tgtccctatg tccttgatcc
    41521 tgttatggtt gctacaagtg gagatgcctt gattgactca aatgctagag actatctcaa
    41581 aacaaactta ctacctctag caactattat tacgccaaat cttcctgaag cagaagagat
    41641 tgttggtttt tcaatccatg accccgaaga catgcagcgt gctggtcgcc tgattttaaa
    41701 agaatttggt cctcagtctg tggttatcaa aggcggacat ctcaaaggcg gtgctaaaga
    41761 tttcctcttt accaagaatg aacaatttgt ctgggaaagc ccacgaattc aaacctgtca
    41821 cacccatggt actggatgta cctttgctgc agtgattact gctgaactag ccaagggcaa
    41881 gagtctttac caggcagttg ataaggccaa ggcctttatc acaaaagcta ttcaagatgc
    41941 ccctcaactc ggtcatggtt ctggtccagt caaccataca acttttaaag attaagaaaa
    42001 aaaactctct agttcccact ttaagggaat tagagagttt ttatactctt cgaaaatctc
    42061 ttcaaactac gtcagcttcc atctgcaacc tcaaaacact gttttgagct gacttcgtca
    42121 gtcttatcta aaacctcaag gcagtacttt gagcaacctg cgactagctt tctagtttac
    42181 tctttgattt tcattgagta ttaattagga aagaatgtca tgcaactttg ttaaaaaggc
    42241 ttgcgttttt gcctcaatat cttctgcttg catcaaatca cgtacaacag ctacaccagc
    42301 tatgccagtg cccataagct gatcaatatt ctccgaagtc aagcctccaa tagcaactac
    42361 tggaatggca accgtttggc aaattgtttt caaggtcgat atcagagtaa tgggcgcatt
    42421 ttccttggtg gtggttggga aaatggctcc tgtacccaag taatctgcac ctgatttctc
    42481 cgcttccaga gctcttttaa ccgttttagc ggtgacaccg aggatttttt caggacccaa
    42541 gactttgcga gctaccgaaa ctggtaattc atcatctccg atatgcagac ctgctgcatc
    42601 aaccgcaaga caaacatcca accgatcatc gattatcaag gggacctgat aggcatctgt
    42661 tatttccttg acttgttttg ccagttgata atattgattg gttgtgagat ttttttctcg
    42721 caattggact atggtaaccc ctgaacggca ggccgtctca atttttgcaa gaaagctttc
    42781 cacggaatct tgatagcgat tggttaccag atatagtcta agtgcttctc tattcataaa
    42841 cctctccttt gatggtatct agccaatttt catctcttct taggagcgaa agctgattga
    42901 gtacttggta acgaaattct tccaatccca ttccttgaac aactattttc tcagcagcga
    42961 tattgagata agagactgct aagcaagaag cttcaaaacc agtctttcct tggctgagaa
    43021 aaacagctgt taaggctcca accaagtctc ctgtccctgt tatccagtct aattcagtac
    43081 agccatttcc cagtacagcg acctgatttt tcgaaacgac gaggtccttg ggacctgtga
    43141 ctaagaaaga cataccagga taggtctgac accagtcttt caagacttga agcaaatcct
    43201 ccgtttcttg atctttagca ctcgcatcga ccccaacgcc gtggtgcttt aatccaacaa
    43261 gacttcgaat ttctgacatg tttcctttaa ggaccgtagg tctatagtct aaaaggtctt
    43321 taactaagct cttacgaatg gatgaagtcg ttacgccaac cgcatctact accatcggga
    43381 gagaagattg gtttgcatac gaagctgcca tgcggattgc tttctccttc tcagctgaca
    43441 aatgccccaa attgatgaag agagcctgac tttgcttagt aaaatcaaga acctcacggg
    43501 gatcatctgc catgacaggt ttgcatccca gagccaaaat cccatttgcc agcatctcac
    43561 aagaaatctc attggtcata cagtgaatga gggaactaga gcctatagga aagggatttg
    43621 taaattcctg catcagtcta tcctttcact aaagaaatat ccctgcactt ttttaaagaa
    43681 ttcctgcttg attaaaaatc gaaaggcaat aaaggaaatc gctgtaccaa tcaaggttgc
    43741 tccgaaaaat cgaggcgtgt agataaacca gctaagctta gcagctgatc ctgtaaagag
    43801 taccataaca ggataggaaa caatagaacc aataatacct gttcccacaa tttctcccaa
    43861 ggcagaaaag taaaattttc gaccgtactt ataaaagaga cctgctagaa gggctccaaa
    43921 agtcgctcct gtgagagcta aaggcggaat cccttgagtc gtcatacgga taaaggctgt
    43981 cactgtagcc atagccaagg cataaacagg tcccatcatg attcccgcta gaatattgac
    44041 tacactggac atcggtgcca ttccctcaat ccgaaagata ggtgtaagga ctacatcaag
    44101 ggcaatcatc atagataaaa tggtcaattt gtgaacttgt agttggtgct ttctcatgtt
    44161 tctattcttc tcctttttct aaagactgta aatcgctctt ccatgtctgg tgttggtaag
    44221 ccatctccca aaacttggct tccatatgaa cactgatgtg gaaggcatct agcatttttt
    44281 gcttatctgt ctcatcactt tctcgataga gctgattgac cagtgctccc tcctctctga
    44341 tctgttgctc taactcatcc gtaatataag tttcaatcca ttgttgatag agaggatttg
    44401 gtgatggttt aagattaagt gatttgccta tatcatggta taaccaagga caaggaagca
    44461 agcttgcaaa agctatggct aagttcggtt ctgcaaattg cctataaata tgagaaatgt
    44521 aatgataaca ggttggagcg attggatgtt gctccatttc ctggtcgttg atttccaatt
    44581 ccttgaaaaa ttgttggcga ataaataact caccctccac taaaccctga gcattttgtt
    44641 tcaagagtct tttcatctct tggtttgaag tcttatcagc caaaagatga tagatttctg
    44701 agaaggcctt cagatagtag gcatcctgaa tcaggtaata gcggaaaatg gcaggttcta
    44761 aattcccctc ttgtaattgt aaaataaagg gatgatgaaa ggaagcctgc caagctttct
    44821 tggataattc catcgcaata tctgtaaatt ccataataac tcctttataa aaatagactg
    44881 gtttgaagca ataaaaagaa aagcaggtag attaattttg tttttttagg aatataaaaa
    44941 gtccgatagc tattcttcaa ctgtgcatgt tcgtcatatc catgagcaga cagagctctc
    45001 aggtaaagat ggcgccacct aaagactgtc atcagaacct tactgtaaat caagggcgac
    45061 caaaaatgca gttcttgacc acgtaatagg caagcttctt tgagggactt gatttcttgc
    45121 tgaatgagag gaaaggaatt gaataccaca atcaaggcat aggaccaaga gcgtgatagc
    45181 cccttttgag ccaagtacaa gagaagctct tttagtgaaa tagaggaaac aaagacaagg
    45241 ccgatacaaa ctgtcacaaa ggccctcgtt ccaagcatga ctgcctgtga agcatctccg
    45301 tgtaactgaa ctgcccagta gttggcaaaa gatggtaaaa tggcaagtat gatcatccaa
    45361 gctaacattt taaatcgacg gtaatagagc ataaagagaa tacaaaatgc gactaccgaa
    45421 agattcagag caatcgaagg aatgaaagat gtttccaagg ataaaatcag caagaagaga
    45481 ctgataatcg gtgtctgggt tgctactttg accatactat ctcacctccc cttgggtatt
    45541 gctactctga gatgtaagtg gtttggtaat ggtcacttct ttcacatgcc gaagaccctg
    45601 actagtcatc tcaatccaat aatcaaccac agaaatcaaa gggtctaaac gatgactaat
    45661 gagcagaaaa cttcttcctt gattcctctc ctccacaatc cacttgcaaa aataatggca
    45721 ggctctatca tccaaacctg caaaaggttc atctagcaag atcacggaag ccttactggt
    45781 caagatggtc aagagctgaa gaattttttg ctgaccacca cttaattgat agggactctt
    45841 atcgactgcc tgctccaaat caaaatatcg taaagcttga aaaatccgct gatttctttc
    45901 agaatcaggt ccatctaatt gaagctcctc tcgcagactg actcggataa actgcttctc
    45961 agcttcctga acaatactcg tcagttcacg gtacaaactc tttttctttt tcaggactgt
    46021 ccccttccat gcaatgcgcc ccttatactt ttgaaattga agaatagacc gaaagagggt
    46081 tgatttccca acaccattgt cacccaggat acaggaaatt ccttggtaaa atgtaaaatc
    46141 agcaatcgaa aagagggagc gatttccaaa ctcacaagtc gttctatcca tatggaatag
    46201 ttccgggcta gaagcaactt cctttgaagc aacctgtgtc atctcatagg aagggatttg
    46261 aaacacttcc cttagttttc cgtctcttag ctcaaccata tggtcgatat aggctttata
    46321 gtcagataaa tcatggtcgc acaaaataac tgtcttccca tcaagagcca actcttttag
    46381 aatctccaat atctcgattc tgctcttgcg gtcaatggaa gcgaagggct catccaagag
    46441 atatacccta ggattcatgg caaagaggac agccatcgct gctttttgct tttccccacc
    46501 tgataggtga tgaatgggac ggtgtaagat tgcctcgcaa cgacattgct ggacaacctc
    46561 tgctatttta gaatcaattt cctgaaggtg atagccgata ttctccaagg tgaaaatcag
    46621 ctcctcaaac aagttctcca tggtaaattg atgattggga ttttgaaaga gaatgccaac
    46681 cttctggata cgtgcgatga tagaaagctg actgacctcg ctcccatcta tcaggacttg
    46741 accactatag ggaagagaac tgacttgggc aatgacttga aaaaggctgg attttcctga
    46801 accactgctc ccaactaaca aggtaaaggc ttgcgcatga aaagtaaaat caaacggctc
    46861 agagaagatt ggggactgaa tcgctcgtag ttccagaccc atctatgctt ttcctccagt
    46921 tgcaaactga tgatagagtt tgacaatggc acgaaccaag atggtacaga agaaataaac
    46981 agaaataaaa cgtaccacaa gtaaggaaag gacaaacgga agggaaaagg cgtagtaacc
    47041 taacttaatg tattcataga caaagctaac aagcgtaatc ccaatactat tagcagttag
    47101 agagagccaa ctttcatagc gattcttagt tacgataaaa ccaaattcac ttcccaaacc
    47161 ttgaaccaag ccagacaaaa gagctcctag accaaattgg ctaccataaa ggacttcagc
    47221 aagcgcagct agcacttctc caatcgttgc acttccgact ctcggaacaa agatggcagc
    47281 aatgggcgca gccatacacc agagaccgaa gaggatttca ttggcaaagg cctgcaaacc
    47341 aagaggtgtt aagagtagac tgaaaatatt atacacatat cctgaaccaa cgaaaacccc
    47401 accaaaaaag atagacaaga aagcaagcaa gataacatct tttaactgcc attttttcaa
    47461 cataaaaaac tcctttttta aagaaaagtg ggacactcaa gaagaccgac ctaaatactt
    47521 tgtatagcag actgaattta gaacagtaca caagaatgct aaaatatttc tagaaattaa
    47581 tttgaatttt ctaattgatt tgttcgcatc ttatttcaat ctactatatc atcttcatcc
    47641 agtttcgtaa aagaaaaaac tctaattaca gatacgaatt agagttcagc ttacaagatt
    47701 agacagttct tttcgacata cgaaaaaaac atttcacatt tcccttcgcc agtcttaact
    47761 gtatcaggtt caatgggtat catctcagcc taaagcaccc caaatgtctt tattatttaa
    47821 ttatgtgatt attataacac acattttata ctagttcaag aaattgaact ggaaatacag
    47881 ccttgcactc acaaagacag cagatctttc ttttgcaaaa aacaaatgac ctgtttgatg
    47941 aattagccat tcaagctgaa tctggacata gctttttaaa aaaggaaaat cctacttact
    48001 tagaatccaa ggatagatat ctattgttca ctcatttccc gaacagtttt ttctatattt
    48061 tttgcatacg atattgccga aatgattgaa acgccatcca tattggtctt tataatgtct
    48121 ttaatatgtt tcgtctgtat cccaccaatt gcaactaaag gcatttgtgg caatagtttt
    48181 ctcatcaatt caagaccttc ataacctata gcaccaccag catcatcttt tgactgggta
    48241 tcaaatacag gcccaacacc tacataatct acatattcaa cttttgattg ttgaaattct
    48301 tcttcgtttc ttatagaaag accaattatt ttatctggca tcaattttct aatttcatca
    48361 acaccaatat catcttgacc tacatgtacg ccatcggcgt caatttccat tgctaaatct
    48421 atatcgtcat taacgataaa tggaacattg tattttttac aaagttcttt aatttggata
    48481 gctagctcaa gtttttctaa gccttctaaa gcaccctcac ctttttctcg aaattgaaat
    48541 aaggttatac caccttttaa ggcttcctca acgactgtat atagattttt tccttggcaa
    48601 gtagtcgttc cacaaataaa atatagtttt agtaattctt tatgaaacat cttacttcac
    48661 tcttttgaat tcctttacat cttcatctgt aatctcgtat aaggcattta taaattcaac
    48721 tttaaatgtc ccaggaagat gtccatttgg acgtttttct gccatttctc cagcgatatt
    48781 gtaaactaac attgctgttt ctaatgattt taattcttga cctttttcca gtccgataaa
    48841 acttgctact acagctccta ataagcatcc tgtcccaatg actttcggca tcatagcact
    48901 accattatga atcgttacca cttctccatt aacagcaatg gcatccactt cacctgttac
    48961 tactattgga atattgaact tctcatttgc tgctagagca atttcgtcaa tattatctac
    49021 gcccgcacta tctactcctt tagatgccac atctattcct actaaagagg caatctcgcc
    49081 agcatttcct ctaatcgctg ctagtttata attgttgatt agatcatctg ctactttttt
    49141 tctatattct cctgctccac aggctacagg atctaaaact gctgggacat tatatttctc
    49201 tgcaattttc agagcagctt ggtataattt ccaattttca tctgtcaatg ttcctatgtt
    49261 tattaataaa ccaccagcat actttaacaa atcctctaaa tctgctggaa actcactcat
    49321 ggctggtgag gcgcccagtg ctactaatcc atttgctgtg aaatttttta ctacatcatt
    49381 ggttatacaa atgaccaatg gtgctttttc ttttaataat tttaaacttg tcatattgaa
    49441 atccttcctt ttcactttat acgatctact gatttcgatt tatttctatc tttcgttaag
    49501 aatttttttc atttacattg aatgatttat actcaatgaa aatcaaagag caaactagga
    49561 ggctaaccgc aggttgctca aaacactgtt ttgaggttgt ggatagaact gacgtggttt
    49621 gaagagattt tcgaagagtc ttacctcatc aaatttgtaa atatcatgag ccttctctag
    49681 acatcgtaac caatatcaaa aaaagctaat tctaaagcga ctgcttgatt ccagcgttgc
    49741 tgaagttctg tcaaatcttc tcgattttta ccgacacgat tgagttcgtc aaccagaaat
    49801 tgaacccact ctgcaaagaa aggacctctg tggagattga tccattccga atgaatatag
    49861 acttcaggta aagccaaatc tttagaaccc cagtctaaat agagaccttc tgcaatgacc
    49921 aacatgacca aaagatgggc atagtctgat gaagccaccg ccgaatacat tagatcctga
    49981 aaggcttttg ttacagggtg caaagtcact tctagatagt cattctctgc tacttttaac
    50041 tctttaaaag ccttttggaa ataaccatct tcatctgctt caagaaagcc tagttgcttg
    50101 gcaaaacgaa gcttggattc aagtttatct gcgtgagcta cgcaggcacc cagcatggat
    50161 aagaaggcat caaagaagtg ataatcttga atcagatagt cctttaagac cttattctca
    50221 attgtccccg caaaaagttc cttaacaaaa cgatgattga ttgcagcctg ccaatccttc
    50281 tgactgcttt ttaataattc tccaacagtc aaacctggct gaaatgcata gttttgtgtt
    50341 tccatattta cttctcctct ctttacttgt tagtaattaa taaaacacca agaaatatca
    50401 agtaaaatcg taattccact tgatcctttt aaagcacatc gagagcattt gcagagagct
    50461 aactaaacaa gcctatccag tttatataaa caaaaaactc caattacaat caagaattag
    50521 agttgactta caagattaga ccgttcattt cgccatacga aaaaacgttt cacatttccc
    50581 ttcgccagtc ttaactgtat caggttcaat gggtattatc tcagcctaaa gcaccccaaa
    50641 tgtctctatt atttaattac tgaaccagta tagcaaaaaa tgaaagccct agcaagatat
    50701 ttgaccgaaa aatatcttta tatataatat attgaaacta gaatagtaca cctctacttc
    50761 taaaacattg ttagaaatcg atttgactgt cctaattgat ttgtcctatt cttatttcat
    50821 tttactatag ttttcgatag caatttattc ttccaataca cgaagaaaaa cctccacatt
    50881 cagtggaggc aatctgtttt atcaatacaa ttttaagtca cgagggtcaa ctgggaaggt
    50941 tgggttgtat ggattgtgac ggagcttgaa gtgtttgaca tcttcaatgg tctgagttcc
    51001 agacaattgc ataactgtct tcaattccgc attcaagtgt tcaaagactt gacgcacacc
    51061 gacactacca ccgagagcca agccatagat gacagggcgt ccaatagcaa ccaagtctgc
    51121 tcctgatgcc aaggctttaa agacgtgttg accacgacga acaccagagt caaagacaat
    51181 cggcacacgt ctatcaactg cttctgccac ttcttgaagc gagtcaaagg cagctggtcc
    51241 accgtcgatt tgacgaccac cgtggttggt tacccagata ccagaagctc ctgcagcaag
    51301 cgaacgttca acgtcctcac ggcattgtgg tcccttgaca tacacaggaa gaccagagta
    51361 ttcagcgata aattctacat cgcgtggaga caagcgttgt ttagctgatt tgtaaacaaa
    51421 gtccattgat ttaccagcac cttctggcag gtattcttca acaatcggca tgccaactgg
    51481 gaagacaaaa ccattacgct tatccacttc acgattcccc cctacagtag catctgccgt
    51541 caagacaatc gctttataac cttcagcctt cacacggtcc atgatgtggc ggttgatacc
    51601 gtcatcctta ctaaagtaaa attgaaacca atgaggtgtc ccttgaaggg cttcagaaat
    51661 ctctggaagg tcaacagtag agtaagaact ggttgtataa agagaaccaa actcatgcac
    51721 accacgcgca gtcgccactt ccccctgttc atttgccaat ttatgagccg caacaggtgc
    51781 cataatgatt ggagaagata gtttttcacc tgcaaattca atctctgtac ttggattttc
    51841 tacattgcaa agtgtatgag gaacgatgag cttgtggtta aaggcacgga tattctctct
    51901 taaagtgaaa gtatcttccg ccccactagc gatatagcca aatgctgctt taggaataac
    51961 ttgttgcgcc attggctcca aatcataggt attgatgaag tctacatgac cttctgcatt
    52021 gcttgttttg tatgacataa aatgccctcc ttgattaagt aagcgtttgc tttttactac
    52081 acaactataa taactctttt ttcaatcatt ttcaagagtt ttgcttaaaa accatcttat
    52141 tttttcatac aatatactag ccctactttc cttaaactct aaaccttatt ctatattaag
    52201 tgaatcgttg agattttttg ctgccaggca tttgaactac ttttttattt gcggattcta
    52261 tctactaata ctataaaaaa acaagtgaat aagacaccag aacatcctct aataggacct
    52321 atggacttat atcagtccca tatatactgt ttaagcaaga tactatccta gttgacgcta
    52381 acttcctatc ccacttatta attttttatt tatagtgaat ctgaacaaat caattgggga
    52441 atccaagtca atttctagta ctttttgaac agtttcagcg tactatcgta aaatgaaata
    52501 aaacatgcac aaattgatta gggaatttaa accaatttct aacaatgtct tagaaatcaa
    52561 agtgtactat ttcaacttca atatactaca cttcattttc tccttaaatt cagtctcttt
    52621 ttgaatcaaa aaatcctctg gtaagagcca gaggataaaa atttatttca ttgttgggaa
    52681 gagcaataca tcacggatag ttgttgtatc agtgaggagc atgcagagac ggtcgatacc
    52741 gattcccaaa ccacctgttg gtggcatacc gtattcaaga gcttcaatgt agtcatagtc
    52801 gattcctgtc gcttcatcgt caccaagttc ttttgctttt gcttgggctt caaagcgact
    52861 aagctggtcg attgggtcgt tcaactcagt aaaggcatta ccgtactcct tagtcatgat
    52921 aaagagctcg aaacggtcag taaagcgttg gtcttcagga tttttcttag cgagtggaga
    52981 tacagctact ggatgtccat agacaaaggt tggttggatt aaagtttctt caacaaactc
    53041 ttcaaagaag gcattgatga tgtgaccaac ctcagtgtag tgtttctcaa ctggaacttt
    53101 cttctcagca gcgatagctt tagcttcttc caaagtcatg tcttgccaga aatcgacacc
    53161 agtaatttct ctgatagcat ccaccatatg aacacgctta aatggttcgt taatcttgat
    53221 ttcagtacct tggtagttga ctgggccatc acctttgact gatttagcag cgtgttggat
    53281 aatgccttca gtcaagtcca tgatgtcttg gaagtctgca taagcttggt aaacttcgat
    53341 agaagtgaac tcagggttat gagtagcgtc cattccttcg ttacggaaga tacggccaat
    53401 ttcatagaca cgttccatac cacccacgat aaggcgtttt aagtgaagct cagtcgcgat
    53461 acgaagcacc atgtcaatgt tttgggcatt gtggtgggtg ataaatggac gggcagcagc
    53521 accaccggct tcattatgaa gaacaggtgt ttccacttca aggaatcctt tttggtcaag
    53581 gtaacgacgg atttcagaga tgatttttga acgagtgaca aagcgttcaa agctttcacg
    53641 attagaaatc aagtcaaggt aacgtttacg gtaaattgtt tcaacgtctg tcaaaccatg
    53701 gaatttctca ggaagaggac gaagagcctt agacaagtgt gtgatgtggg ttgccttgat
    53761 agagagttct cccatatccg tacgcatcac ttcaccttcg acaccaagga agtcaccaag
    53821 gtctgctttt ttgaagattt cgtagttttc ttcaccgaca gcatccttac gaacgtagat
    53881 ctgaatctgg ccttcgcggt cttgaaggtg ggcaaaacca acttttcctt taccacgttt
    53941 ggttaccaag cgtcctgcga tagtagctgt ttcgttttta tcgtgtaatt gttctttatc
    54001 gaggttggca tatttatctt ttaattcttg tgaatttgca gtacgttcaa aacgttttcc
    54061 gaaaggatcg attccttgtt cgcggagcgc agccattttt tcacggcgaa cgatctgctg
    54121 gtcatttagt tcttccatat gttctgtaga catgggatcc tcctagtttt actcaaaatt
    54181 gaatacgatg agtcattttt tgcgataccc ccattttatc ataaataagc aagaaattca
    54241 cggataatct ttaaaaacta aaaagaacct gacgctaaaa tcactggaaa gaagtgaaag
    54301 tatctcccgc cccactagcg atatagccaa atgctgcttt aggaataact tgttgcgcca
    54361 ttggctccaa atcata
//
LOCUS       DAVLXH010000009        50276 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00028199
            SAMN33607166-rid17955573.denovo.009, whole genome shotgun sequence.
ACCESSION   DAVLXH010000009 DAVLXH010000000
VERSION     DAVLXH010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607166
            Sequence Read Archive: SRR23725544
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 50276)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 50276)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721421.1
            Genome Coverage       :: 115x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:42:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,210
            CDSs (total)                      :: 2,161
            Genes (coding)                    :: 2,023
            CDSs (with protein)               :: 2,023
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 73 of 138
            Pseudo Genes (incomplete)         :: 60 of 138
            Pseudo Genes (internal stop)      :: 40 of 138
            Pseudo Genes (multiple problems)  :: 31 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..50276
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607166-rid17955573.denovo.009"
                     /strain="AUSMDU00028199"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1349"
     gene            581..877
                     /locus_tag="VYO11_000596"
     CDS             581..877
                     /locus_tag="VYO11_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000911560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HEV1595197.1"
                     /translation="MLKFRKVVASSLAVLAFSLALPVLAVSHRGGEWTYGGHHDPYNW
                     GAFSNYYHGSQYHWAYVGSNERDNQKTVYAGAHSAAYAFVNTNLGERITFDAGW"
     gene            980..2995
                     /locus_tag="VYO11_000597"
     CDS             980..2995
                     /locus_tag="VYO11_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEV1595198.1"
                     /translation="MKKLFILISNLLASLFFVWVFTIWTDTYVSHYYPNVVVHDSSPE
                     TTFQHVATRLEKLAEETDSFIAIQHQDPNSEGTTVFSYTTFGDGKLPDGLQEKKLEDA
                     QSSSVETNYFVFDGHLDIHLLREELSQLGLTNMHLTIPSKLSTLMAIFSNGFQLISLL
                     IFILTFGALTLISQISQLRSSGIRLISGEKRWSIFLRPVGEDLKGIAVGFSLAGVLTI
                     LMQKILSLPTQSLMTIGAGLLSYNLILLSISLFFAQLFAVGIKKIHLMQIIKGQVPVR
                     GIISLILIGQLLAIIIVTLGIGSSLKYSQAWQQHRIGQEAWSQERQLITLSISREGTS
                     PGFDEQAQRKLRTWYQLMDLAVSEQKAFLSRHQLIDRTLQNGMASSKNLITSTEWHDY
                     NPNGNVLIVTPQYLERQNIPVDTTIEQKMNHLDVGEFVLLLPEHLRSEEEHYKSVFED
                     DLTSRMSSQDERQQMTATVGYLESGQDRFVYNTTPISYQQFLKDPIIIVITPQSTGPQ
                     SILFWIDAVQNYVLFNQLSDAQELIQRQGIENWVSEMQTGYHNYITLLDNIQRERWVM
                     LAGAVLGIATSILLFNTMNRLYFEEFRRAIFIKRIAGLRFLEIHRTYLFAQLGVFLLG
                     FVASVFLQVEIGVAFLVLLLFTGLSLLQLHVQMQKENKMSMLVLKGG"
     gene            2997..3629
                     /locus_tag="VYO11_000598"
     CDS             2997..3629
                     /locus_tag="VYO11_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1595199.1"
                     /translation="MIELKQVSKSFGERELFSNLSMTFEAGKVYALIGSSGSGKTTLM
                     NMIGKLEPYDGTIFYRGKDLANYKSSDFFRHELGYLFQNFGLIENQSIEENLKLGLIG
                     QKLSRSEQRLRQKQALEQVGLVYLDLDKRIFELSGGESQRVALAKIILKNPPFILADE
                     PTASIDPATSQLIMEILLSLRDDNRLIIIATHNPAIWEMADEVFTMDHLK"
     gene            complement(4575..4988)
                     /gene="ndk"
                     /locus_tag="VYO11_000599"
     CDS             complement(4575..4988)
                     /gene="ndk"
                     /locus_tag="VYO11_000599"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000438285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HEV1595200.1"
                     /translation="MEQTFFIIKPDGVKRGLVGEVLKRIEQRGFTIEKLEFRSQVSEE
                     LIDQHYQDLVGQSFYPPIREFMTSGPVLVGVISGPKVIETWRTMMGATRPEEALPGTI
                     RGDFAKAAGENEIIQNVVHGSDSEESAKREIALWF"
     gene            complement(5099..8776)
                     /gene="rpoC"
                     /locus_tag="VYO11_000600"
     CDS             complement(5099..8776)
                     /gene="rpoC"
                     /locus_tag="VYO11_000600"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000228741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HEV1595201.1"
                     /translation="MVDVNRFKSMQITLASPSKVRSWSYGEVKKPETINYRTLKPERE
                     GLFDEVIFGPTKDWECACGKYKRIRYRGIVCDRCGVEVTRTKVRRERMGHIELKAPVS
                     HIWYFKGIPSRMGLTLDMSPRALEEVIYFAAYVVIDPKDTPLEHKSIMTEREYRERLR
                     EYGYGSFVAKMGAEAIQDLLKQVDLEKEIAELKEELKTATGQKRVKAIRRLDVLDAFY
                     KSGNKPEWMILNILPVIPPDLRPMLQLDGGRFASSDLNDLYRRVINRNNRLARLLELN
                     APGIIVQNEKRMLQEAVDALIDNGRRGRPITGPGSRPLKSLSHMLKGKQGRFRQNLLG
                     KRVDFSGRSVIAVGPTLKMYQCGVPREMAIELFKPFVMREIVARDIVQNVKAAKRLVE
                     RGDERIWDILEEVIKEHPVLLNRAPTLHRLGIQAFEPVLIDGKALRLHPLVCEAYNAD
                     FDGDQMAIHVPLSEEAQAEARILMLAAEHILNPKDGKPVVTPSQDMVLGNYYLTMEEA
                     GREGEGMVFKDRDEAVMAYRNGYVHLHSRVGIATDSLNKPWTEEQRHKVLLTTVGKIL
                     FNDIMPEGLPYLQEPNNANLTEGVPAKYFLPLGGDIKEAISNLELNPPFKKKNLGNII
                     AEIFKRFRTTETSALLDRMKNLGYHHSTLAGLTVGIADIPVVDDKAEIIEESHKRVEQ
                     ITKQFRRGMITDDERYNAVTAEWRAAREKLEKRLIANQDPKNPIVMMMDSGARGNISN
                     FSQLAGMRGLMAAPNGRIMELPILSNFREGLSVLEMFFSTHGARKGMTDTALKTADSG
                     YLTRRLVDVAQDVIIREDDCGTDRGLLIRSIAEGKEMIESLEERLNGRYTKKTVKHPE
                     TGAVIIGPNELITEDKAREIVNAGVEEVTIRSVFTCNTRHGVCRHCYGINLATGDAVE
                     VGEAVGTIAAQSIGEPGTQLTMRTFHTGGVASNTDITQGLPRVQEIFEARNPKGEAVI
                     TEVKGQVTAIEEDASTRTKKVFVKGETGEGEYVVPFTARMRVEVGGQVARGAALTEGS
                     IQPKRLLAVRDVLSVETYLLGEVQKVYRSQGVEIGDKHIEVMVRQMIRKVRVMDPGDT
                     DLLMGTLMDINDFTDANKDVLIAGGVPATGRPVLMGITKASLETNSFLSAASFQETTR
                     VLTDAAIRGKKDHLLGLKENVIIGKIIPAGTGMARYRNLEPHAVNEEEYLNPPVEEEG
                     NEETTEVVVDTAVETVEETVE"
     gene            complement(8809..12420)
                     /gene="rpoB"
                     /locus_tag="VYO11_000601"
     CDS             complement(8809..12420)
                     /gene="rpoB"
                     /locus_tag="VYO11_000601"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000907130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEV1595202.1"
                     /translation="MAGHDVQYGKHRTRRSFSRIKEVLDLPNLIEIQTDSFKAFLDHG
                     LKEVFEDVLPISNFTDTMELEFVGYEIKEPKYTLEEARIHDASYSAPIFVTFRLINKE
                     TGEIKTQEVFFGDFPIMTEMGTFIINGGERIIVSQLVRSPGVYFNDKVDKNGKVGYGS
                     TVIPNRGAWLELESDSKDITYTRIDRTRKIPFTTLVRALGFSGDDEIFDIFGDSELVR
                     NTVEKDIHKNPMDSRTDEALKEIYERLRPGEPKTAESSRSLLVARFFDPRRYDLAAVG
                     RYKINKKLNVKTRLLNQTIAEPLVDPETGEILVEAGTIMTRSVIESIESHLDGDLNKI
                     VYIPNDAAVVTEPVVLQKFKVVAPTDPDRVVTIIGNANPDDKVRTVTPADILAEMSYF
                     LNLAEGLGRVDDIDHLGNRRIRAVGELLANQVRLGLSRMERNVRERMSVQDNEVLTPQ
                     QIINIRPVTAAVKEFFGSSQLSQFMDQHNPLSELSHKRRLSALGPGGLTRDRAGYEVR
                     DVHYTHYGRMCPIETPEGPNIGLINNLSSYGHLNKYGFVQTPYRKVDRETGVVTNEIV
                     WLTADEEDEYTVAQANSRLNEDGTFAEKIVMGRHQGVNQEYPANIVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPYVGTGMEYQAAHDSGAAVIAQY
                     DGKVTYADADKVEVRREDGSLDVYHIQKFRRSNSGTAYNQRTLVKVGDVVEKGDFIAD
                     GPSMENGEMALGQNPIVAYMTWEGYNFEDAVIMSERLVKDDVYTSVHLEEYESETRDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVKEGDILVGKVTPKGEKDLSAEERL
                     LHAIFGDKSREVRDTSLRVPHGADGVVRDVKIFTRVNGDELQSGVNMLVRVYIAQKRK
                     IKVGDKMAGRHGNKGVVSRIVPVEDMPYLPDGTPVDIMLNPLGVPSRMNIGQVMELHL
                     GMAARTLGIHIATPVFDGASSEDLWSTVKEAGMDSDAKTILYDGRTGEPFDNRVSVGV
                     MYMIKLHHMVDDKLHARSVGPYSTVTQQPLGGKAQFGGQRFGEMEVWALEAYGASNVL
                     QEILTYKSDDINGRLKAYEAITKGKPIPKPGVPESFRVLVKELQSLGLDMRVLDEDDQ
                     EVELRDLDEGMDEDVIHVDDLEKAREKAAQEAKAAFEAEEAEKATKAEATEEAAEQE"
     gene            12835..12905
                     /locus_tag="VYO11_000602"
     tRNA            12835..12905
                     /locus_tag="VYO11_000602"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:12867..12869,aa:Cys,seq:gca)
     gene            complement(13103..14434)
                     /locus_tag="VYO11_000603"
     CDS             complement(13103..14434)
                     /locus_tag="VYO11_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HEV1595203.1"
                     /translation="MEDPSSQNLLLQFVLLFILTVLNAFFSATEMAMVSLNRARVEQK
                     AEEGDRRYIRLLKVLENPNHFLSTIQVGITLITILSGASLTDTLGRVIASWLGNGETA
                     QAVATFLSLAFLTYISIVFGELYPKRIALNLKDALAIRTAPVIIGIGKLVSPFVWLLA
                     ASTNFLSHLTPMSFDDADEKMTRDEIAYMLTNSEETLDADEIEMLQGVFSLDELMARE
                     VMVPRTDAFMVDIQDDSQAIIQSILKQNYSRIPVYDGDKDNVIGIIHTKSLLKAGFVD
                     GFDNIVWKRILQDPLFVPETIFVDDLLKELRNTQRQMAILLDEYGGMAGLVTLEDLLE
                     EIVGEIDDETDKAAIDVHQIGEDTYIVQGTMTLNDFNNYFDVELESDDVDTIAGYYLT
                     GVGTIPTTEKLSYELVSQNKQFILTNDKVKNGRVTKVKVQITEVEIEEETE"
     gene            complement(14725..15549)
                     /gene="endA"
                     /locus_tag="VYO11_000604"
     CDS             complement(14725..15549)
                     /gene="endA"
                     /locus_tag="VYO11_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-entry nuclease EndA"
                     /protein_id="HEV1595204.1"
                     /translation="MNKKTRQTLIGLLVLLLLSAGSYYIKQNELGNQAAKTKMSQKKQ
                     APEAPSQELAESVLTDAVKSQIKGSLEWNGSGAFIVNGNKTNLDAKVSSKPYADNKTK
                     TVGKETVPTVANALLSKATRQYKNREETGNGSTSWTPPGWHQVKNLKGSYTHAVDRGH
                     LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEYSTGQNYYESKVRKALDQNKRV
                     RYRVTLYYASNEDLVPSASQIEAKSSDGELEFNVLVPNVQKGLQLDYRTGEVTVTQ"
     gene            complement(15588..15776)
                     /locus_tag="VYO11_000605"
     CDS             complement(15588..15776)
                     /locus_tag="VYO11_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEV1595205.1"
                     /translation="MNKKSGYVIKRLLLVILVLILGLLALGIGLMVGYGILGKGQDPW
                     AILSPAKWQELIHKFTGN"
     gene            complement(15769..17052)
                     /gene="murA"
                     /locus_tag="VYO11_000606"
     CDS             complement(15769..17052)
                     /gene="murA"
                     /locus_tag="VYO11_000606"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HEV1595206.1"
                     /translation="MDKIVVQGGDNRLVGSVTIEGAKNAVLPLLAATILASEGKTVLQ
                     NVPILSDVFIMNQVVGGLNAKVDFDEEAHLVKVDATGDITEEAPYKYVSKMRASIVVL
                     GPILARVGHAKVSMPGGCTIGSRPIDLHLKGLEAMGVKISQTAGYIEAKAERLHGAHI
                     YMDFPSVGATQNLMMAATLADGVTVIENAAREPEIVDLAILLNEMGAKVKGAGTETIT
                     ITGVEKLHGTTHNVVQDRIEAGTFMVAAAMTGGDVLIRDAVWEHNRPLIAKLLEMGVE
                     VIEEDEGIRVRSQLENLKAVHVKTLPHPGFPTDMQAQFTALMTVAKGESTMVETVFEN
                     RFQHLEEMRRMGLHSEIIRDTARIVGGQPLQGAEVLSTDLRASAALILTGLVAQGETV
                     VGKLVHLDRGYYGFHEKLAQLGAKIQRIEANDEDE"
     gene            complement(17076..17306)
                     /locus_tag="VYO11_000607"
     CDS             complement(17076..17306)
                     /locus_tag="VYO11_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014017351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HEV1595207.1"
                     /translation="MVQLLFTLSSHMLFIYVSFYLLKDLVRWEKVLKVTDDNTRKVRL
                     LVAFFSIVIGYILSSFFISLYHLWQEALRGLL"
     gene            complement(17364..18401)
                     /locus_tag="VYO11_000608"
     CDS             complement(17364..18401)
                     /locus_tag="VYO11_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HEV1595208.1"
                     /translation="MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLK
                     VNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFTDIRSAQETTGGSSDVEFMRINQ
                     FYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
                     DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVIS
                     NVPISFSTAGIGGPSAGLMFSLAIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGID
                     KKVVASARADAAIFFAPDNPVSEEEQKAHPDAKNNYQTALEAAKTIKTDMKIVPVKTL
                     QDAIDYLKNNP"
     gene            complement(18385..18873)
                     /gene="coaD"
                     /locus_tag="VYO11_000609"
     CDS             complement(18385..18873)
                     /gene="coaD"
                     /locus_tag="VYO11_000609"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HEV1595209.1"
                     /translation="MSDKIGLFTGSFDPMTNGHLDIIERASRLFDKLYVGIFFNPHKQ
                     GFLPLENRKRGLEKALGHLENVEVVASHDKLVVDVAKRLGATFLVRGLRNAADLQYEA
                     SFDYYNHQLSSDIETIYLHSRPEHLYISSSGVRELLKFGQDIACHVPESILEEIRNEK
                     KD"
     gene            complement(18863..19402)
                     /gene="rsmD"
                     /locus_tag="VYO11_000610"
     CDS             complement(18863..19402)
                     /gene="rsmD"
                     /locus_tag="VYO11_000610"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HEV1595210.1"
                     /translation="MKIISGIYGGRPLKTLEGKTTRPTSDKVRGAIFNMIGPYFEGGR
                     VLDLYAGSGGLSIEAVSRGMSSAVLVERDRKAQTIVAENIQMTKEVGKFQLLKMDAER
                     ALEQVSGEFDLVFLDPPYAKEQIVADIEKMAERELFSEDVMVVCETDKAVELPEEIAC
                     LGIWKEKIYGISKVTVYVR"
     gene            complement(19467..20459)
                     /locus_tag="VYO11_000611"
     CDS             complement(19467..20459)
                     /locus_tag="VYO11_000611"
                     /EC_number="6.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016502595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
                     /protein_id="HEV1595211.1"
                     /translation="MKKSFIHQQEEISFVKNTFTQYLKDKLEVVEVQGPILSKVGDGM
                     QDNLSGVENPVSVKVLQIPDATYEVVHSLAKWKRHTLARFGFGEGEGLFVHMKALRPD
                     EDSLDATHSVYVDQWDWEKVIPNGKRNIVYLKETVEKIYKAIRLTELAVEARYDIESI
                     LPKQITFIHTEELVERYPDLTPKERENAICKEFGAVFLIGIGGELPDGKPHDGRAPDY
                     DDWTSESENGYKGLNGDILVWNESLGGAFELSSMGIRVDEETLRRQVEITGDEDRLEL
                     EWHKSLLNGLFPLTIGGGIGQSRMAMFLLRKRHIGEVQTSVWPQEVRDTYENIL"
     gene            complement(20572..21255)
                     /locus_tag="VYO11_000612"
     CDS             complement(20572..21255)
                     /locus_tag="VYO11_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HEV1595212.1"
                     /translation="MNHTIIHDRAGLNQFYAKVYAFVGLGIGLSALVSGLMLTVFQSQ
                     LVYLLMQGRLWLTIATFAELALVFVASSMASRNSPAALPVFLLYSVLNGFTLSFVVAF
                     YTPGTVLSAFVSSALLFFVMAAVGIFTKKDLSGIGRAMMAALIGLLIAMVVNIFLASG
                     FFDYMISVAMVLVFSGLIAWDNQKIRLAYEQSQGRVATGWVVSMALSIYLDFINLFLS
                     ILRIFGRND"
     gene            complement(21311..22051)
                     /locus_tag="VYO11_000613"
     CDS             complement(21311..22051)
                     /locus_tag="VYO11_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HEV1595213.1"
                     /translation="MTIITSKANSVVKNAKKLHQKKYRKSAYLIEGWHLFEEAVQAGV
                     TIEKIFALENYRDQLAAFPQTVWISEDILLDLADSQTPQGIVAVVQKEEVGQADLSQG
                     KFLFLEDVQDPGNVGTIIRTADAAGFTGVIVSDKSADIYSLKTLRSMQGSHFHLPIYR
                     MTSQALLDETKKVAIPVLATTLSKDSVDYRELPSIENFVLVMGNEGQGISPLMAESAD
                     QLVHISMKGQAESLNVAVAAGILIFHLS"
     gene            22085..22363
                     /locus_tag="VYO11_000614"
     CDS             22085..22363
                     /locus_tag="VYO11_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001174612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HEV1595214.1"
                     /translation="MQKVRMIAQGRVQGVGFRWGVYSLALEIGGITGRVWNNDDGTVE
                     ILAQADSSAIMAKFIQEIRKGPTPFSKVSYLDVKLSNFPPYSDFKIAN"
     gene            22441..23367
                     /gene="yidC"
                     /locus_tag="VYO11_000615"
     CDS             22441..23367
                     /gene="yidC"
                     /locus_tag="VYO11_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HEV1595215.1"
                     /translation="MKSIKRFAFSAMGVAMLLVLTGCVNVDKTTGQPTGFIWNTIGAP
                     MAEAIKYFATDKGLGFGVAIIIVTIIVRLIILPLGIYQSWKATLHSEKMNALKHVLEP
                     HQTRLKEATTQEEKLEAQQALFAAQKEHGISMFGGVGCFPLLLQMPFFSAIYFAAQHT
                     EGVAQASYLGIPLGSPSMILVACAGVLYYLQSLLSLHGVEDEMQREQIKKMIYMSPLM
                     IVVFSLFSPASVTLYWVVGGFMMILQQFIVNYIVRPKLRKKVREELAKNPPKASAFST
                     PSGRKDVTPEQPTAITSKKKHKNRNAGKQRSR"
     gene            complement(23442..24236)
                     /gene="pflA"
                     /locus_tag="VYO11_000616"
     CDS             complement(23442..24236)
                     /gene="pflA"
                     /locus_tag="VYO11_000616"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001288284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HEV1595216.1"
                     /translation="MSEETIDYGQVTGMVHSTESFGSVDGPGIRFIVFLQGCHMRCQY
                     CHNPDTWAMESNKSRERTVDDVLTEALRYRGFWGNKGGITVSGGEALLQIDFLIALFT
                     KAKEQGIHCTLDTCALPFRNKPRYLEKFDKLMAVTDLVLLDIKEINEEQHKIVTSQTN
                     KNILACAQYLSDIGKPVWIRHVLVPGLTDRDDDLIELGKFVKTLKNVDKFEILPYHTM
                     GEFKWRELGIPYSLEGVKPPTADRVKNAKQLMDTESYQDYMKRVHG"
     gene            complement(24362..25612)
                     /locus_tag="VYO11_000617"
     CDS             complement(24362..25612)
                     /locus_tag="VYO11_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000856498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HEV1595217.1"
                     /translation="MKTPFINREELEAIVAEFPTPFHLYDEKGIREKARAVNQAFSWN
                     KGFKEYFAVKATPTPAILKILQEEGCGVDCSSYVELLMSHKLDFLGSEIMFSSNNTPD
                     KEYAYARELGATINLDAFEDIEHLERVAGIPEIISCRYNPGGVFELGTDIMDNPGEAK
                     FGMTKDQLFEAFAILKEKGAKTFGLHSFLASNTVTHLYYPELARQLFELAVEIKEKLG
                     ISLDFINLSGGIGVNYRPDQEPNDIALIGEGVRKVYEEVLTSAGLGQVKIFTELGRFM
                     LAPHGALVTRVTHKKETYRTYLGVDASAVNLMRPAMYGAYHHISNVTHPDGPAEAVDV
                     VGSLCENNDKFAVNRELPHTEIGDLLVIHDTGAHGFSMGYQYNAKLRSAEILYTEEGK
                     ARQIRRAERPEDYFATLYGFDFEE"
     gene            complement(25679..26506)
                     /gene="purR"
                     /locus_tag="VYO11_000618"
     CDS             complement(25679..26506)
                     /gene="purR"
                     /locus_tag="VYO11_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004242125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HEV1595218.1"
                     /translation="MKLRRSDRMVVISNYLINNPYKLTSLNTFAEKYESAKSSISEDI
                     VIIKRAFEEIEIGHIQTVTGAGGGVIFTPSISSQDAKEMVEDLRTKLSESDRILPGGY
                     IYLSDLLSTPAILKNIGRIIAKSFMDQKIDAVMTVATKGVPLANAVANVLNVSFVIVR
                     RDLKITEGSTVSVNYVSGSSGDRIEKMFLSKRSLKAGSRVLIVDDFLKGGGTVNGMIS
                     LLREFDSELAGVAVFADNAQEEREKQFDYKSLLKVTNIDVKNQAIDVEVGNIFDEDK"
     gene            complement(26773..27714)
                     /locus_tag="VYO11_000619"
     CDS             complement(26773..27714)
                     /locus_tag="VYO11_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exoribonuclease YhaM family protein"
                     /protein_id="HEV1595219.1"
                     /translation="MKISHMKKDELFEGFYLIKSADLRQTRAGKNYLAFTFQDDSGEI
                     DGKLWDAQPHNIEAFTAGKVVHMKGRREVYNNTPQVNQITLRLPQAGEPNDPADFKVK
                     SPVDVKEIRDYMSQMIFKIENPVWQRIVRNLYTKYDKEFYSYPAAKTNHHAFETGLAY
                     HTATMVRLADAISEVYPQLNKSLLYAGIMLHDLAKVIELTGPDQTEYTVRGNLLGHIA
                     LIDSEITKTVMELGIDDTKEEVVLLRHVILSHHGLLEYGSPVRPRIMEAEIIHMIDNL
                     DASMMMMSTALALVDKGEMSNKIFAMDNRSFYKPDLD"
     gene            complement(27704..28960)
                     /locus_tag="VYO11_000620"
     CDS             complement(27704..28960)
                     /locus_tag="VYO11_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombination protein RmuC"
                     /protein_id="HEV1595220.1"
                     /translation="MESLLILLLIANLAGLFLIWQRQDRQEKHLSKSLEDQADHLSDQ
                     LDYRFDQARQASQLDQKDLEVAVSDRLQEVRIELHQGLTQVRQEMTDNLLQTRDKTDQ
                     RLQALQESNEQRLEQMRQTVEEKLEKTLQTRLQASFETVSKQLESVNRGLGEMQTVAR
                     DVGALNKVLSGTKTRGILGELQLGQIIEDIMTPAQYEREYATVENSSERVEYAIKLPG
                     QGDQEYVYLPIDSKFPLADYYRLEEAYEVGDKDEIERCRKSLLASVKRFARDIRNKYI
                     APPRTTNFGVLFVPTEGLYSEIVRNPVFFDDLRREEQIIVAGPSTLSALLNSLSVGFK
                     TLNIQKSADHISKTLASVKTEFGKFGGILVKAQKHLQHASGNIDELLNRRTIAIERTL
                     RHIELSEGEPALDLLHFQENEEEYED"
     gene            complement(28962..29624)
                     /locus_tag="VYO11_000621"
     CDS             complement(28962..29624)
                     /locus_tag="VYO11_000621"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000006147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HEV1595221.1"
                     /translation="MSEYKLSENNWTRVAVFADGNRGHYRTDFDAFVGVDRGSLWVLE
                     EDLPLALAVGDFDSVTEEERQVIQKRAQHFVQARPEKDDTDLELALLTIFEQNPQAEV
                     TIFGALGGRIDHMLANVFLPSNPKLAPYMRQIEIEDGQNLIAYCSEGTSQLEPRSDYD
                     YLAFMPVRDSQLTILGAKYELTEENFFFKKVYASNEYIDREVSVTCPDGYVVVLHSKD
                     RR"
     gene            complement(29587..30243)
                     /locus_tag="VYO11_000622"
     CDS             complement(29587..30243)
                     /locus_tag="VYO11_000622"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HEV1595222.1"
                     /translation="MSQYKIAPSILAADYANFEREIKRLEATGAEYAHIDIMDSHFVP
                     QISFGAGVVESLRPHSKMVFDCHLMVSNPEHHLEDFARAGADIISIHVEATPHIHGAL
                     QKIRLLGVKPSVVINPGTPVEAIKHVLHLVDQVLVMTVNPGFGGQAFLPETMDKVREL
                     VALREEKGLNFEIEVDGGIDDQTIAQAKEAGATVFVAGSYVFKGEVNERVQTLRKQLD
                     "
     gene            complement(30254..31132)
                     /gene="rsgA"
                     /locus_tag="VYO11_000623"
     CDS             complement(30254..31132)
                     /gene="rsgA"
                     /locus_tag="VYO11_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HEV1595223.1"
                     /translation="MQGQIIKALAGFYYVESDGQVYQTRARGNFRKKGHTPYVGDWVD
                     FSAEENSEGYILKIHERKNSLVRPPIVNIDQAVVIMSVKEPDFNSNLLDRFLVLLEHK
                     GIHPIVYISKMDLLEDRGELDFYRQTYGDIGYDFVTSKEELLSLLTGKVTVFMGQTGV
                     GKSTLLNKLVPDLNLETGEISDSLGRGRHTTRAVSFYNLNGGKIADTPGFSSLDYEVS
                     RAEDLNQAFPEIATVSRDCKFRTCTHTHEPSCAVKPAVEEGVIATFRFDNYLQFLSEI
                     ENRRETYKKVSKKIPK"
     gene            complement(31134..32006)
                     /gene="rsmA"
                     /locus_tag="VYO11_000624"
     CDS             complement(31134..32006)
                     /gene="rsmA"
                     /locus_tag="VYO11_000624"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HEV1595224.1"
                     /translation="MRIADYSVTKAVLERHGFTFKKSFGQNFLTDTNILQKIVDTAEI
                     DDQVNVIEIGPGIGALTEFLAERAAQVMAFEIDHRLVPILVDTLRDFDNVTVVNEDIL
                     KVDLAQHIQNFKNPNLPIKVVANLPYYITTPILMHLIESGIPFCEFVVMMQKEVADRI
                     SAQPNTKAYGSLSIAVQYYMTAKVAFIVPRTVFVPAPNVDSAILKMVRRPEPAVAVED
                     ENFFFKVSKASFTHRRKTLWNNLTGYFGKTEEVKDKLTKALDQAGLSPSVRGEALSLA
                     EFAGLADALKGQGL"
     gene            complement(32137..32445)
                     /locus_tag="VYO11_000625"
     CDS             complement(32137..32445)
                     /locus_tag="VYO11_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1595225.1"
                     /translation="MCEKIRIRRVSDYPSARGGLEDILIMENMTNHLLLVQIRVHGYL
                     LDFASIEGQRQKHYRLKNLPQTVELTVDDVEEDVDLTLPENRSYQEADFFERMFRENC
                     "
     gene            complement(32438..33079)
                     /locus_tag="VYO11_000626"
     CDS             complement(32438..33079)
                     /locus_tag="VYO11_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1595226.1"
                     /translation="MIDIQGLEKKFNDRAIFSGLNLKLEKGKVYALIGKSGSGKTTLL
                     NILGKLEKIDGGRVLYQGKDLKTIPTREYFRDQMGYLFQNFGLLENQSIKENLDLGFV
                     GQKISKVERLERQVGALEKVNLGYLDLEQKIYTLSGGEAQRVALAKTILKNPPLILAD
                     EPTAALDPENSEEVMNLLVDLKDENRIIIIATHNPLVWNKADEIIDMRKLAHV"
     gene            complement(33081..35111)
                     /locus_tag="VYO11_000627"
     CDS             complement(33081..35111)
                     /locus_tag="VYO11_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000825281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEV1595227.1"
                     /translation="MKRLFILISMVLVSLYMVITSVDHREEILFGNYPSVDVTGMMTN
                     QPVASREEVTEALSHLAVEHNSLIARRIVEPNEAGETRFTYATYGEGELPEGLTISSK
                     ESAETSDLLGSYLIVSGSLDGVSLQTTLKELGYQGFVSNGEDPFSIVLLLTATPMVLL
                     SLAIFLLTFMSLTLIYRIKSLRQAGIRLIAGESLFGVALRPVLEDVRQLICSVLVSSL
                     LGLGILWYQGALFMATVQLVIIALLLYGLTLAGISTLLSVVHLLGLQENSLVDLLKGK
                     LPLKRMMTLMMVGQLLAVLVVGSSATALLPHYREMQEMERASNKWSQSSDRYRLSFGW
                     SSAFADEEGTRKDNREWQTFTEERLANTDSFYIMSNVDNFSDGAEVDLDGNRLSDYTP
                     SGNVIYVSPRYLIEEKITVSSEFMDKMQNLSEGEFGLILPESLREQSVYYQGLFTDYL
                     QNFSSESVEVTSQKHYLPQVRLAFTETGQERFLYNDGYKTTRQYLKDPIIVVLTPQAT
                     GTRPVAGMLWGTTANSALKLDRYGDSITALKEQGLYHKVSYLVKSQLFFAKVLNDKRV
                     EFYSLLIGTILTLSTAILLFDSMNLLYFEQFRRELMIKRLAGMTIYELHGKYLLAQGG
                     VLLLGLVLSSILTRDGLISALVVALFTLNALLILVRQDKKEEAGSMAVLKGK"
     gene            complement(35188..35484)
                     /locus_tag="VYO11_000628"
     CDS             complement(35188..35484)
                     /locus_tag="VYO11_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000815395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HEV1595228.1"
                     /translation="MKQTVKKLALVASIAATLGGSVAVASAAVQYPEGGVWTYGSGNG
                     GAYSNYYHPSKYHSSTVVSRKTGSSDKGYAGAGGTSRAWIRTSWGEKVAFYYNV"
     gene            complement(35804..36703)
                     /locus_tag="VYO11_000629"
     CDS             complement(35804..36703)
                     /locus_tag="VYO11_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1595229.1"
                     /translation="MLIGQKIKEIRIEKGVSRPDFCGDEQELTVRQLSRIESGASQPS
                     LPKLAYIARRLGVPVYSLMPDFSALPPAYLELKYQILREPIYGKEEEYDKKEACLEEI
                     YKTYFDNLPKEEQLACEVLQACLDTSRTRRPEYAELILEEHMSQIIEKEVYSTNDMLL
                     IRLFFYQMLIRKDLAKFINQIEKLMLFLLEQKKVTKLENFFIIRDTLISGMCCLEKVG
                     VTDCFNDYLSCLQEIMDKTQDYQKKPLVFMFLWKQALREERDFSLAESFYQSSKTFAQ
                     LIGDEFLVKKLTEEWQEDVKKYL"
     gene            complement(36775..37335)
                     /gene="rnmV"
                     /locus_tag="VYO11_000630"
     CDS             complement(36775..37335)
                     /gene="rnmV"
                     /locus_tag="VYO11_000630"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HEV1595230.1"
                     /translation="MKEKISQVIVVEGRDDTVNLKRYFDVETYETRGSAINDQDIERI
                     QRLHQRHGVIVFTDPDFNGERIRRMIMTVIPTVQHAFLKRDEAVPKSKTKGRSLGIEH
                     ASYEDLKTALAQVTEQFEHESQFDISRSDLIRLGFLVGADSRKRREYLGETLRIGYSN
                     GKQLLKRLELFGVTLAEVEEAMKSYE"
     gene            complement(37335..38108)
                     /locus_tag="VYO11_000631"
     CDS             complement(37335..38108)
                     /locus_tag="VYO11_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HEV1595231.1"
                     /translation="MIFDTHTHLNVEEFAGREAEEIALAAEMGVTQMNIVGFDKPTIE
                     RALELVDEYEQLYATIGWHPTEAGTYTEEVEAYLLDKLKHPKVVALGEIGLDYHWMTA
                     PKEVQEQVFRRQIQLSKDLDLPFVVHTRDALEDTYEIIKSEGVGPRGGIMHSFSGTLE
                     WAEKFVDLGMTISFSGVVTFKKATDLQEAAKELPLDKMLVETDAPYLAPVPKRGRENK
                     TAYTRYVVDFIADLRGMTTEELAVATTANAERIFGLDSK"
     gene            complement(38404..39078)
                     /locus_tag="VYO11_000632"
     CDS             complement(38404..39078)
                     /locus_tag="VYO11_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000153804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1542 domain-containing protein"
                     /protein_id="HEV1595232.1"
                     /translation="MTILGKDTVQQSAKGESVTQEATPEYKPETTLGVDKGGNTGSSD
                     ANANAGGGSQAGGPAHTGSQNSAQSQASKQLATEKESAKNAIEKAAKDKQDEIKGAPL
                     SDKEKAELLARVEAEKQAALKEIENTKTMEDVKEAETIGVQAIAMVTVLKRPVAPNAA
                     PKTTSAPQATAGTMQDVTYQSPAGKQLPNTGSASSAALASLGLVAATSGFALLGRKTR
                     RRKWNS"
     gene            complement(39341..39475)
                     /gene="rpmH"
                     /locus_tag="VYO11_000633"
     CDS             complement(39341..39475)
                     /gene="rpmH"
                     /locus_tag="VYO11_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HEV1595233.1"
                     /translation="MKRTYQPSKLRRARKHGFRNRMSTKNGRRVLAARRRKGRKVLAA
                     "
     gene            complement(39620..40834)
                     /locus_tag="VYO11_000634"
     CDS             complement(39620..40834)
                     /locus_tag="VYO11_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEV1595234.1"
                     /translation="MKEYNKSSKLEHVAYDIRGPVLEEAMRMRANGEKILRLNTGNPA
                     EFGFTAPDEVIHDLIMNARDSEGYSDSKGIFSARKAIMQYCQLKKFPNVDIDDIYLGN
                     GVSELIVMSMQGLLDNGDEVLVPMPDYPLWTAAVSLAGGNAVHYICDEAVEWYPDIDD
                     IKSKITSNTKAIVLINPNNPTGALYPKELLLEIIEIARQNDLIIFADEIYDRMVMDGH
                     VHTPVASLAPDVFCVSMNGLSKSHRIAGFRVGWMVLSGPKTHVKGYIEGLNMLSNMRL
                     CSNVLAQQVVQTSLGGHQSVDELLLPGGRIYEQRNFIYNAIQDIPGLSAVKPKAGLYI
                     FPKIDRNMYRIDDDEQFVLDFLKQEKVLLVHGRGFNWQEPDHFRIVYLPRVDELAQIQ
                     EKMTRFLKQYRR"
     gene            complement(40990..41283)
                     /locus_tag="VYO11_000635"
     CDS             complement(40990..41283)
                     /locus_tag="VYO11_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009014348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1595235.1"
                     /translation="MMKNSFQKSNFLYYGIILVSVLVEVIMICQLESLVPLLYPSFIG
                     FLVFHVLYHLILFLVAKRSGRWDYLMIWGLFLMFNLLYDSFLGLLFLGLSFGM"
     gene            41445..41897
                     /locus_tag="VYO11_000636"
     CDS             41445..41897
                     /locus_tag="VYO11_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HEV1595236.1"
                     /translation="MAQRYQNIMVAIDGSKEADLAFVKGVHSALRNDAKLTIAHVIDT
                     RALQSVSTFDAEVYEELQVDAESLMKEYEKRAKDAGVADVHIVIEMGNPKTLLARTIP
                     DAEEVDLILVGATGLNAFERLLVGSSSEYILRHAKVDLLVVREQEKTL"
     gene            complement(41932..43320)
                     /locus_tag="VYO11_000637"
     CDS             complement(41932..43320)
                     /locus_tag="VYO11_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000453140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV1595237.1"
                     /translation="MEVKAVFFDIDGTLVNNRKSVLKSTKDAIKIVKEQGVLVGVATG
                     RGPFFVKELMDDLDLDFAVTYNGQYIFSKDRVLFTSPISKLHLRHLISYAKKEGTEIA
                     LGTKDAMLGSKIMSFGLGSFSQRISRFVPSVLTRTVSQSFNRMVSKVVPQKEEDLLHL
                     MNQPIYQVLMLMTPEESEKAAADFEDLKLTRSNPFASDVINQGNSKLEGIRRVGKEYG
                     FDLNQVMAFGDSDNDLEMLAGVGMSVAMGNGSSSVKEAAKHITTSNQQDGIHKALEHF
                     GVLSSEKVFVSRDYHFNKVKTFHHMMDERTQEEPRAWDLEGATHRAGFKIEELVEFVR
                     AASPSEEDFGQAVSQLHQALDKAADKVAKKTPAQQDLIGQVDALIDTLYFTYGSFVLM
                     GVDPERIFDIVHQANMGKIFPDGKAHFDPVTHKILKPDNWEEKYAPEPAIKKELQRQL
                     KAYERHKERNKS"
     gene            43386..44348
                     /locus_tag="VYO11_000638"
     CDS             43386..44348
                     /locus_tag="VYO11_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HEV1595238.1"
                     /translation="MPKKILVLHTGGTISMQADASGAVVTSSDNPMNHVSNPLEGIQV
                     HALDFFNLPSPHIKPKHMLVLYQKIKEEADNYDGVVITHGTDTLEETAYFLDTMEVPH
                     MPIVLTGAMRSSNELGSDGVYNYLSALRVASDDRAADKGVLVVMNDEIHAAKYVTKTH
                     TTNVNTFQTPTHGPLGLIMKQEILYFKTAEPRVRFDLDHIQGLVPIISAYAGMTDELI
                     DMLDLEHLDGLIIQAFGAGNIPKETAQKLESLLQKGIPVSLVSRCFNGIAEPVYAYQG
                     GGVQLQKAGVFFVKELNAQKARLKLLIALNAGLTGQALKDYMEG"
     gene            complement(44554..45564)
                     /gene="ccpA"
                     /locus_tag="VYO11_000639"
     CDS             complement(44554..45564)
                     /gene="ccpA"
                     /locus_tag="VYO11_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000990602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HEV1595239.1"
                     /translation="MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEV
                     IDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFSSLAKGIDDIAEMYKYNIVLANS
                     DEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
                     VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGIAYSEGL
                     VFESKYSYDDGYALAERLISSNATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSD
                     DSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREVLLPHGLTERSSTRK
                     RK"
     gene            complement(45989..46588)
                     /locus_tag="VYO11_000640"
     CDS             complement(45989..46588)
                     /locus_tag="VYO11_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1595240.1"
                     /translation="MKVLVAEDQSMLRDAMCQLLTLQPDVESVLQAKNGQEAIQLLEK
                     ESVDIAILDVEMPVKTGLEVLEWIRSERLETKVVVVTTFKRAGYFERAVKAGVDAYVL
                     KERSVADLMQTLHTVLEGRKEYSPELMEVVMTRPNPLTEQEIAVLKGIARGLSNQEIA
                     DQLYLSNGTIRNYVTNILSKLDAGNRTEAANIAKESGWL"
     gene            complement(46590..47687)
                     /locus_tag="VYO11_000641"
     CDS             complement(46590..47687)
                     /locus_tag="VYO11_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV1595241.1"
                     /translation="MLERLKSIHYMFWASLIFMIFPILPVVTGELPAWHLLVDILFVV
                     TYLGVLITKNQRISWLFWGIMLVYVAGNTAFVAGNYIWFFFFLSNLLIYHFGVRSLKS
                     LHVWTFLLAQVLVVGRLLIFQRIEVEFLVYMLVILTFVDLMTLGSVRIRLVEDLKEAQ
                     VKQNTQINLLLAENERNRIGQDLHDSLGHTFAMLSVKTDLALQLFQMQAYPQVEKELR
                     EIQQISKESMREVRTIVENLKSRTLTSELETVKKMLEIAGIEVETDNQLDTASLTQEL
                     ESMASMILLELVTNIIKHAKASKAYLKLERTEKELILTVSDDGCGFAFLKGDELHTIR
                     DRVFPFSGEVSVISQKHPTEVQVRLPYKERN"
     gene            complement(47687..48424)
                     /locus_tag="VYO11_000642"
     CDS             complement(47687..48424)
                     /locus_tag="VYO11_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1595242.1"
                     /translation="MKRWIALSKIEFLLTKRQLIYYLLSVGMPTAFYLFFSGIYQDTP
                     GELANFMRDYLISMTAFSMMSTTILSFPAVLHTDKMNNWQKTLRHSPVNMVEYYLSKI
                     TSMLVDYLVSILVVFTVGHFVRGVDMPLVKWVGAAILLIVGSIAFVALGLTLTLLPTS
                     QLMSVVGNLLYLGLAVLGGLWMPISLFPDWMQAVGKCLPTYQLMELLKTFLNEGGINL
                     SATVYLLVFSAVLFGLTIYLQGHKENA"
     gene            complement(48426..49310)
                     /locus_tag="VYO11_000643"
     CDS             complement(48426..49310)
                     /locus_tag="VYO11_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1595243.1"
                     /translation="MTVVKVEKLSKKIKDKEILRNISFEINDGECVALIGPNGAGKTT
                     LLDCLLGDKLVTSGQVSIQGLPVTSSKLDYTRAYLPQENVIVQKLKVKELIAFFQRIY
                     PNPLSNQEIDQLLQFVKQQKEQLAEKLSGGQKRLFSFVLTLIGRPKIVFLDEPTASMD
                     TSTRQRFWEIVQELKAQGVTILYSSHYIEEVEHTADRILLLNKGELIRDTTPLAMRSE
                     EIEKHFILPIAYKEVVEQSNLVENWTLKQDSLQVVTREADAFWELLAQAGCRMQEIEV
                     NNRSLLNTIFEETQKGDN"
     gene            complement(49297..49491)
                     /locus_tag="VYO11_000644"
     CDS             complement(49297..49491)
                     /locus_tag="VYO11_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1595244.1"
                     /translation="MKRGIIYFFIGLSLLVWLVEMFTDWFDQALLRQFIRGALGFGFM
                     IFVVFLMGMEWLKGESHDGG"
     gene            complement(49488..49694)
                     /locus_tag="VYO11_000645"
     CDS             complement(49488..49694)
                     /locus_tag="VYO11_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000503440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1595245.1"
                     /translation="MGEEEMRNKMIIAVSLVVAGVMTYLMFSGLDEDFYHFPWKVFAG
                     FGIMSWLVREGLKLVRDVKKEFEE"
BASE COUNT        14531 a        11422 c         9573 g        14750 t
ORIGIN      
        1 taaactaaaa aaagtcaaaa attacataaa aatgcttggc taaataaaat atatctgtta
       61 aaataaggat aatgaaaaag aaaagggttt cacgaatgaa gaaaaatcgt ggaattcaaa
      121 aattagctat attagtatta ctaggtgttt ttatgtttag taatacaatt ccttaccaac
      181 agtttattca gaagaataga caattggaga ttcgagtgca atcgcaaaag aagtccaatg
      241 gtcttgatgt tgggaaggct gattgatttc gtattacttt aaaattcaac tatttagaga
      301 aaggtattct gatgagagct tgtaacaata ccagatagat ataagaatgg agatgtttga
      361 taaaatgctt tcatagctaa ccaactgttg aaaattatga gttacaaaat ctaaagtatt
      421 taagattggt ttataaaatt aggtctctgc ctgtagaaag gaacgtgcag ttagaaagga
      481 ggaaaaaata ggatactata attcagactg agatttctaa ttaaaatatg tagttgcatt
      541 tcgctcattt tcataatatt tcatttagag gagtaataat atgttaaaat ttagaaaagt
      601 agttgcatca tcccttgccg ttttggcatt tagtttggct cttcctgttt tggcagtttc
      661 tcaccgtggt ggcgagtgga cctatggagg ccatcatgat ccatataatt ggggagcatt
      721 ttcgaattat tatcatggtt cacagtatca ctgggcctat gttggaagta atgaacgtga
      781 caatcaaaaa acagtttatg caggagcaca tagtgcggcc tatgcgtttg ttaatacaaa
      841 tttgggggag cgaattacat ttgatgcggg atggtaaaga ataattgaag aagattcttt
      901 tatcaatagt ttagtaagct tgttagttta tagagggcag gggtatttct gccctctgtt
      961 ttagaataag gaatgcacta tgaaaaaatt atttatactc atatccaacc tgcttgctag
     1021 tttgttcttt gtttgggtat ttaccatttg gactgataca tatgtctccc attattaccc
     1081 caacgttgtt gtacatgatt cttcccctga aacaactttt cagcatgttg ctacacgctt
     1141 ggaaaaacta gcagaagaaa cagatagctt tattgcgatt caacaccaag atcctaactc
     1201 agaaggtact acagtttttt cttatacgac ctttggagac ggaaagttgc ctgacgggct
     1261 acaggaaaaa aaactagaag atgctcaaag tagtagtgtt gaaacaaact attttgtatt
     1321 cgatggacac ctagatattc acttgctaag ggaggagcta agtcaacttg gcttgactaa
     1381 tatgcacctg acaattccat ctaaactatc tacgttaatg gctatcttta gtaacggatt
     1441 tcagttaatc agtctattga ttttcatctt aacctttgga gcactgactt taattagtca
     1501 aattagccaa ttacggtcgt cgggcattcg cctcatttca ggagagaaac ggtggtccat
     1561 ttttcttaga ccagttggtg aggatttgaa agggatagct gttggtttca gtttagctgg
     1621 cgtgctcacc attcttatgc aaaaaattct gtcgcttcca acgcaatccc taatgaccat
     1681 aggagcaggc ttgctcagtt ataatctcat cttgttgtct atctccctgt ttttcgctca
     1741 actcttcgca gttgggataa aaaagataca cctgatgcag attataaaag ggcaagtgcc
     1801 tgtcagagga atcattagtt tgattttaat cggtcaacta ttagcgatta ttattgtaac
     1861 gctgggaata gggagtagct taaagtattc ccaagcctgg caacagcatc ggattggaca
     1921 agaggcttgg agtcaggaaa ggcaactgat taccctatca atcagccgtg aaggaacgag
     1981 tcctggtttt gatgaacaag ctcaaaggaa actcagaact tggtatcaat tgatggatct
     2041 ggctgtttca gaacaaaagg ctttcttatc tagacaccag ttaattgacc gtactttgca
     2101 aaatggcatg gcttcctcca aaaacttgat aacctctaca gaatggcacg attacaaccc
     2161 gaatggcaat gtccttatcg tcacaccgca atacttggag cgtcaaaaca ttcctgtaga
     2221 tacaactatt gagcaaaaga tgaatcacct tgatgtaggg gagtttgtct tattgctgcc
     2281 tgaacacctc cgttcagagg aagaacatta taaatctgtt tttgaagacg acttaaccag
     2341 tcgcatgtct agtcaagatg aacgacagca aatgactgct acggtaggtt atttagaatc
     2401 aggtcaggat cgttttgtgt ataatacgac ccctatttct taccagcagt ttttgaaaga
     2461 tccaatcatc attgttataa caccccaatc aactggtcca cagtccattt tgttttggat
     2521 agacgcagta cagaactacg ttctctttaa tcaattgtct gatgcccagg agcttatcca
     2581 gagacaaggc attgaaaatt gggtctcaga aatgcaaaca ggttaccaca actacatcac
     2641 attattggat aatatccaga gggaacgttg ggtaatgcta gcaggagctg tgcttgggat
     2701 tgcaacttca atcttgttgt ttaacactat gaataggctc tactttgaag aatttagacg
     2761 tgccattttt atcaaacgca ttgcaggtct caggttctta gaaatccatc gcacttatct
     2821 ctttgctcaa ctgggtgtgt ttttactggg atttgttgcg agtgtatttc ttcaggtaga
     2881 gataggagtt gctttcttag tcttgttact ctttactggt ctatctcttt tacagttaca
     2941 tgtccaaatg cagaaagaaa acaagatgtc catgcttgtt ttgaagggag gttaatatga
     3001 ttgaacttaa acaggtgagt aaatcttttg gagaacgaga gttattttcg aatctttcaa
     3061 tgacatttga ggctggaaaa gtctatgcct taattggttc aagtggtagc ggaaaaacaa
     3121 ccttgatgaa catgattggg aaattagaac cttatgatgg gacgattttt taccgaggta
     3181 aagacttggc caattataaa tcaagtgatt ttttccgtca cgaattgggc tacctcttcc
     3241 agaactttgg cttaattgaa aaccaaagta ttgaagaaaa ccttaagcta ggtctcattg
     3301 gtcaaaagtt gagtcggtcg gaacagcggt tgaggcagaa gcaggcttta gaacaggtcg
     3361 gcctggttta tcttgaccta gataagcgca tctttgagtt atcgggcgga gaatcgcaac
     3421 gggttgcctt ggcaaaaatt atcttaaaga atccaccctt tattctggca gatgagccaa
     3481 cagcttcaat agacccagca acctctcagt tgattatgga gattttgcta tctcttcgag
     3541 atgataatag gctaatcatt atcgcaacac ataatccggc aatttgggag atggctgatg
     3601 aagtgttcac gatggatcat ctgaaataaa aatccttgtt tttaattgca cgatgagtta
     3661 ctgaaatatt atcatgaatc aagaattgga gttaatttag aattgtactt aatttagaat
     3721 tgtactttat taatattgag gtaacttttt cttgataaag gaagaaataa tggagaggaa
     3781 gttagaatga aaaaattcga caattatatt attgagaagc cttgcgattc taattcagat
     3841 aaactgcaaa aaatcttaat aattgaaagt ttggtagatg atattttgca attttctctc
     3901 agaatcaata atagtgtagg agagattttc ctcctacaac cgttttaaaa gaaaactatc
     3961 tttattccat gttattttga ggaagatatt gtgaaagtca aagatgatga taaagttgag
     4021 tggaatttgt tagaatttca aaaatttaga gcatttttgg cttagtaatc tgtgttgaag
     4081 gctcaaaacc tatggtaaaa aagtagcttt gaaaacgtat tgcctccaaa gatttagtta
     4141 aataatgatt taacacaaaa agaaattatt gaagttctgg aaagatgttg tttcagtatt
     4201 gagaaaaggt gggaaaaact tgcgattttc acagagaaag gaagaaaaag tatagaaata
     4261 tagtcaattg aaacaagaac aggataaaag aaccttttgt gccatatttt tctcctttcg
     4321 ctttacaatt ggattgaaca cctttattgt atcgcgtttg gagttttttt ggtataacct
     4381 tcgacgcaca cccgcatagc gggtgttttt tttgtctcgc acctaacgga gcgagacaaa
     4441 ctaatagtca cttaatcaaa aaacgcacca tatcaaaaac taaaaagttt gatatcatgc
     4501 gtcatgtctt aaactaattg actatacttt ctattcaaat gagcttttaa ccaattgatt
     4561 gagccaatcc actcttaaaa ccaaagagca atttctcgct tagctgactc ttctgaatct
     4621 gaaccatgta caacattttg gataatctca ttttctccag cagcttttgc aaaatcacct
     4681 cgaatagtgc ctggtaaagc ttcttctgga cgagttgcac ccatcatggt ccgccaagtt
     4741 tcgattactt tgggaccaga aatgacaccc acaagaactg gacctgaagt catgaattca
     4801 cgaatcggtg ggtaaaaact ctgaccaacc aagtcctgat agtgctggtc aatcaactct
     4861 tctgaaacct gtgaacgaaa ctccaatttt tcgattgtaa atccacgttg ttcgatgcgc
     4921 tttaacactt cacccactag ccctcttttt acaccatctg gtttgatgat aaagaatgtt
     4981 tgttccatac ccgtctcctt tgtcagcttc tttcttttat tttaccacat ttcgtggaaa
     5041 aatggagaaa gttttcagaa gagagaatga gagaacccga gggttctctc attctctctt
     5101 attctactgt ttcttccaca gtttcaacgg cagtatccac aactacttct gttgtttctt
     5161 catttccttc ttcctctact ggaggattaa ggtattcttc ttcgttgaca gcatgtggtt
     5221 caaggttacg gtaacgggcc ataccagtac cagctgggat gatcttaccg atgataacat
     5281 tttctttaag tccaaggaga tggtctttct taccacggat agctgcgtca gtaaggacac
     5341 gagttgtttc ctggaaggaa gccgctgaca agaaactgtt tgtttcaagt gaggctttgg
     5401 taattcccat aaggactggg cgacctgtcg ctggaactcc acctgcgata aggacatctt
     5461 tgttggcatc tgtaaagtca ttgatatcca tgagggtacc catgagaaga tctgtatcac
     5521 ctggatccat gacacggact ttacggatca tttgacgaac cattacctcg atgtgtttgt
     5581 caccgatttc taccccttgg ctacggtaaa ctttttgtac ttcaccgaga aggtacgttt
     5641 caactgacaa gacatcacga actgcaagga gacgttttgg ttggatagaa ccttctgtca
     5701 gagcagcacc acgcgctact tggcccccaa cttcgacacg catacgagct gtaaatggaa
     5761 cgacatattc accttcgcca gtttcaccct taacaaagac tttcttggta cgagttgatg
     5821 catcttcttc gatagcagta acttgtcctt taacctctgt gataaccgct tcccctttag
     5881 gattgcgggc ttcaaagatt tcttggacac gaggaagacc ctgagtgata tcggtatttg
     5941 aggcaacccc acctgtgtgg aaggtacgca ttgtaagctg tgtaccaggt tccccgatag
     6001 attgggcagc gattgtacca actgcttcac caacttcaac cgcatcacca gtcgccaagt
     6061 tgataccgta acagtgacgg cagacaccgt gacgagtgtt acatgtaaat acagaacgga
     6121 tagtcacttc ttccacacca gcattgacaa tttcacgcgc cttgtcttct gtaatcaatt
     6181 catttggacc aataatcact gcaccagttt ctggatgttt aacagttttc ttagtgtaac
     6241 gaccgttgag acgctcttcg agagactcga tcatctcttt tccttctgcg atagaacgga
     6301 tcaagagacc acggtcagtt ccacagtcgt cctcacggat gataacgtct tgggcaacgt
     6361 cgaccaaacg acgagtcaag taacctgagt cggctgtctt aagggccgta tcggtcatac
     6421 ctttacgagc accgtgagtt gagaagaaca tttccaatac cgacaaacct tcgcggaagt
     6481 ttgaaaggat tggcaattcc atgatacgtc cattcggagc agccatcaga ccacgcatac
     6541 cggcaagctg tgagaagttt gagatgttac cacgggctcc agagtccatc atcataacga
     6601 ttgggttctt aggatcttgg ttagcaatca agcgtttctc aagtttttca cgggcagcac
     6661 gccattcagc tgtaacagca ttgtaacgct cgtcgtctgt gatcatacca cgacggaatt
     6721 gtttggtgat ttgttcgaca cgtttgtgtg attcttcaat gatttcagcc ttgtcatcaa
     6781 cgactgggat atcggcaata cccactgtca atcctgcaag agttgagtgg tggtaaccga
     6841 ggttcttcat gcggtcaagt agggcagaag tttctgtcgt acggaaacgt ttaaagattt
     6901 cagcgatgat atttccaagg tttttcttct tgaatggagg gttgagctca agattgctga
     6961 tagcttcctt gatatctcca ccaagtggca agaagtattt agctggaaca ccttctgtca
     7021 agttggcatt gtttggttct tgcaagtatg gtagcccctc tggcatgata tcgttgaaga
     7081 gaattttacc aactgttgta agcaagacct tatgtctttg ctcttctgtc caaggcttgt
     7141 tgaggctgtc tgttgcgata ccaacacgtg agtggaggtg aacataacca ttgcggtaag
     7201 ccataaccgc ttcgtcacgg tctttgaaga ccattccttc accttcgcga ccagcttctt
     7261 ccatggtcaa gtagtagtta cccaaaacca tgtcctgaga tggagtaact accggtttcc
     7321 catctttcgg gttcaagatg tgctcagcag ctagcatgag gatacgagct tctgcttgtg
     7381 cttcttctga aagtggtacg tggatggcca tttggtcccc gtcaaagtca gcattgtagg
     7441 cttcacagac aagtgggtgc aagcgaagag ccttaccatc aatcaagact ggctcgaagg
     7501 cttggatacc caaacggtga agggtcggtg cgcggttcaa aagcactggg tgttctttaa
     7561 tcacttcttc aaggatatcc cagatacgct catctccgcg ttccaccaag cgtttagctg
     7621 ctttgacgtt ttgcacgata tcacgggcaa cgatttcacg catgacaaat ggtttaaaga
     7681 gttcaatcgc catttcacgc ggcacaccac attggtacat cttaagagtt ggaccaacgg
     7741 cgataacgga acgtcctgag aagtcaacac gtttaccgag caagttttga cggaagcgtc
     7801 cctgtttacc tttaagcatg tggctcaatg atttcaatgg acggctacct ggtcctgtga
     7861 ttggacgacc acgacgacca ttgtcaatca aagcgtcaac tgcttcttga agcatacgct
     7921 tctcattttg aacgatgata cctggtgcat ttaactcaag caaacgagcc aaacggttgt
     7981 tacggttgat aacacggcgg taaaggtcat tcaagtcaga tgaggcaaaa cggccaccat
     8041 ccaactgcaa cattggacga agatctggtg ggataaccgg aaggatgtta agaatcatcc
     8101 attcaggttt gtttccagac ttgtaaaagg catccaaaac atccaaacga cggatggctt
     8161 tgacacgttt ttgtccagta gctgttttca attcttcttt gagttcagca atttcttttt
     8221 caagatctac ttgcttcaaa aggtcttgga tggcttccgc acccatcttg gcaacaaatg
     8281 aaccataacc atattcacgc aagcgctctc ggtattcgcg ctctgtcatg atagacttgt
     8341 gctcaagtgg tgtatcctta ggatcaatca ccacataagc cgcaaagtag ataacttcct
     8401 cgagggcacg agggctcata tcaagggtca agcccatacg gcttggaatc cccttgaagt
     8461 accagatgtg agatacagga gctttcaatt cgatatgtcc catacgctca cgacgaactt
     8521 tcgtacgcgt tacttcaacc ccacagcggt cacaaacaat tcctctgtaa cgaatgcgtt
     8581 tgtacttacc acaagcacat tcccagtctt ttgtaggacc aaagatcact tcatcaaaga
     8641 gtccttcacg ttctggtttc aaggtacggt aattgattgt ttcaggtttt ttgacttctc
     8701 cataagacca tgaacggact ttacttggag aagctagggt gatttgcata cttttaaaac
     8761 gatttacatc aaccactatt tcttcccttt ctattctaag tgaactgctt attcttgttc
     8821 agcagcttct tctgttgctt ccgcttttgt tgctttctca gcttcttcag cttcaaaggc
     8881 tgctttagcc tcttgggctg ctttttcgcg ggctttttca aggtcatcta cgtggatgac
     8941 atcttcgtcc attccttcat ccaagtcgcg aagttccact tcttggtcat cttcgtctag
     9001 gacacgcatg tcaagaccaa gagattgcaa ttctttgaca agaactcgga aggattctgg
     9061 aacacctggt tttggaattg gtttgccttt tgtaatagct tcataggctt tcaaacgtcc
     9121 gttgatatcg tccgacttgt aagtcaagat ttcttgaagg acatttgacg caccgtaggc
     9181 ttcaagagcc caaacctcca tctcaccgaa acgttgtcca ccaaactgag ctttacctcc
     9241 gagtggttgt tgggtaacag ttgagtaagg tccgactgaa cgcgcatgca atttatcgtc
     9301 aaccatgtgg tggagtttga tcatgtacat gactccaaca gaaacacggt tatcaaatgg
     9361 ttcacctgta cgtccatcgt aaaggattgt cttggcatcg ctatccatac ctgcttcttt
     9421 aacagttgac caaagatctt cagaacttgc tccatcaaag actggtgtcg caatgtgaat
     9481 accaagagta cgagctgcca taccaaggtg aagctccata acctgaccga tattcatacg
     9541 tgatggcacc ccaagtgggt tcaacatgat gtcgactgga gttccgtctg gaaggtaagg
     9601 catgtcttct acaggaacga tacgagagac aacccctttg tttccgtgac gtccggccat
     9661 tttatctccg accttaatct tacgtttttg agcgatgtaa acacgaacca acatgttaac
     9721 acctgattgc aactcatctc catttacacg tgtaaagatc ttaacatcac gaacgacacc
     9781 atcggcaccg tgtggtacac gaagagaagt atcacgcact tcacgagact tgtctccaaa
     9841 gatagcgtgc aagagacgtt cttcagctga aagatctttc tcacccttag gtgttacttt
     9901 acctacaaga atatcacctt ctttaacctc agcaccaata cggataatcc ccatttcgtc
     9961 aaggtctttg agggcatctt caccaacgtt tggaatttcg cgagtgattt cttcaggccc
    10021 aagctttgta tcgcgcgttt ctgattcgta ttcttcaagg tgaacagatg tgtagacatc
    10081 gtccttcacc aagcgttcgc tcatgataac ggcatcctcg aagttgtaac cttcccaagt
    10141 catgtaggca acgattgggt tttgtccaag cgccatttct ccattttcca tagaaggtcc
    10201 gtcagcgatg aaatcgcctt tttcaacgac gtcaccaact tttacgagag tgcgttggtt
    10261 gtaagcagta cctgagtttg aacgacggaa tttttggatg tggtaaacat ccaatgatcc
    10321 atcttcacga cgaacttcta ccttgtcagc atctgcgtaa gtaactttac catcatactg
    10381 agcaatcaca gccgcaccag aatcgtgggc tgcttggtat tccataccag taccaacgta
    10441 aggtgcctga ggattaatca atggcacagc ctgacgttgc atattggctc ccatgagagc
    10501 acggttggag tcatcgtttt ccaagaaagg aatacatgct gtcgcaacgg caactacctg
    10561 ttttggtgaa acgtccatgt agtcaacaat attagctgga tactcttggt tgaccccttg
    10621 gtgacgtccc atgacaatct tctcagcaaa ggttccatct tcattcagac gagagttagc
    10681 ctgagctaca gtatattcat cttcttcatc agctgtcaac caaacaattt cgttcgtgac
    10741 aacacctgtt tcacggtcaa ccttacggta tggtgtttga acaaaaccat atttgttcaa
    10801 gtgtccgtaa gatgacaagt tattgatcaa accgatgtta ggtccttcag gtgtctcgat
    10861 tggacacata cgaccatagt gagtgtagtg cacgtcacgt acttcatatc cagcacggtc
    10921 acgagtcaaa ccaccaggtc ctaaggctga caaacggcgt ttgtgagaca actcagaaag
    10981 cgggttgtgt tggtccatga actgtgacaa ctgtgatgaa ccaaagaatt ctttaactgc
    11041 agctgttaca ggacggatat tgataatttg ttgtggtgtc aagacttcat tgtcctgaac
    11101 agacatacgt tcacggacat tacgttccat acgagaaagt cccaaacgta cttggttggc
    11161 aagcaattca ccaaccgcac ggatacgacg atttccaagg tggtcgatat catctacacg
    11221 gccaagtcct tcagccaagt tgaggaagta gctcatctca gcaaggatat ctgcaggagt
    11281 caccgtacga accttgtcat ctgggttagc attaccaatg atcgttacga cgcgatctgg
    11341 atcagttgga gcaacaacct tgaatttttg aagaacaaca ggctcagtca caacggctgc
    11401 atcgtttggg atgtagacaa tcttgttcaa gtcgccatcc aaatggcttt caatgctttc
    11461 aatcacgcta cgagtcataa tcgtaccagc ttctaccaag atttctccag tttcagggtc
    11521 taccaatggc tctgcaatgg tttggttgag caaacgtgtt ttaacattga gttttttatt
    11581 gattttgtaa cgaccaactg ctgccaagtc atagcgacgt gggtcaaaga agcgagccac
    11641 aagcaagcta cgtgagcttt cagctgtctt aggctcacct ggacgaaggc gttcgtaaat
    11701 ttctttcaag gcttcgtctg tacgagagtc cattggattc ttgtggatat ctttttcaac
    11761 agtgttgcga accaattcgc tgtcaccaaa gatatcaaag atttcatcat cacctgagaa
    11821 accaagagca cgaaccaagg ttgtaaatgg aatcttacga gtacggtcaa tacgagtgta
    11881 ggtgatatct tttgagtcgc tttcaagttc caaccaagct ccacggttag ggataacagt
    11941 tgaaccatag cccaccttac catttttgtc tactttgtcg ttaaagtaaa cacctggtga
    12001 gcggaccaac tgagaaacga taatacgttc accaccattg atgatgaaag tacccatttc
    12061 tgtcatgatt gggaaatcac caaagaaaac ttcttgggtc ttgatttcgc ctgtttcttt
    12121 attgatcaaa cggaaggtta caaaaattgg tgctgagtag ctagcatcgt ggatacgagc
    12181 ttcttctagc gtgtattttg gttccttgat ttcatatcca acaaattcca actccattgt
    12241 gtctgtgaag tttgaaattg gcaatacatc ttcaaatact tccttaagac cgtggtctag
    12301 gaaagctttg aatgagtcag tttgaatttc aatcaaattt ggtaagtcaa gaacttcttt
    12361 gattcttgaa aaactacgac gggtacgatg tttcccgtat tgaacgtcat gtcctgccaa
    12421 gatgattctc ctttgtaaat aagttccaag ccttgtcaat caggcttttc taatcgccat
    12481 atggttgtaa accccttatc accgtgtcct cttgacgaat tttcagaatc tttaagcctc
    12541 tgttacaaat gctcaaaatc ttgaaaaaaa gcacaaaaag agcagctaaa tctgactttt
    12601 tcagaagatt taactgctgt gagccttgtc tggacaatat ttcagacaaa acctacgaca
    12661 aatgattacc catattatac cctatttagc tagatttttc aaggggattc agtaggtttt
    12721 tggtaatttt tttccataga aaacttggca tcacattcga atcacgctat ggtacaaaaa
    12781 actgaaaaaa ctattgactg aaaatcattt tcaaggtata ataataaacg ttaaggcggt
    12841 atagccaagt ggtaaggcac ggctctgcaa aagcttgatc gtcggttcaa atccgtctac
    12901 cgccttctat aacttgattt atcaggtttc aaatgaacag aaagcccaat ttgaagggtt
    12961 ttttttattt tccctcgaat aaatacgtat aactttaaaa acttttggag cgagtttgtg
    13021 gcagagttct ttccatggca taattccctt ttgaaatcaa ttgaaaaaag cttcgtcacg
    13081 cctggtgaca aaagcctcta gtttattctg tttcttcttc tatttcgact tctgtgattt
    13141 ggacttttac cttggtaaca cgtccattct tcactttatc attggttaag ataaactgtt
    13201 tgttttggct gaccaattca tagctgagtt tctcagtcgt tggaatagtt cccactcctg
    13261 tcaaataata accagcgatg gtatcaacgt catcactttc cagttcaaca tcaaagtaat
    13321 tattgaaatc attgagggtc atagttcctt gaacaatgta ggtatcctcg ccaatctgat
    13381 gaacatctat tgctgctttg tccgtttcat catcaatttc accaacaatt tcctctaaga
    13441 ggtcttccaa agtcaccaaa ccagccatac caccgtattc atccagcaag attgccattt
    13501 gtctttgggt atttcgcagt tcttttagca agtcatccac aaaaatagtt tcaggtacaa
    13561 aaagtggatc ttgcaaaatt ctcttccaaa caatattgtc aaaaccgtcc acaaagcctg
    13621 ccttaaggag actcttggtg tgaatgattc caattacatt gtccttatcc ccatcataaa
    13681 ccgggatacg agaataattt tgttttaaaa tactttggat aatggcttga ctatcatcct
    13741 gaatatccac cataaaggca tccgttcgag gaaccataac ctctcgtgcc atcagttcat
    13801 cgagcgaaaa gacaccttgt agcatctcaa tctcatcagc atccaatgtt tcttcactat
    13861 ttgtcagcat ataggcaatt tcatcacggg tcatcttttc atccgcatca tcgaatgaca
    13921 taggagtcaa atggctcaag aaattggtcg aagcagctaa aagccaaaca aaaggactga
    13981 ctagttttcc gatcccaatg ataaccggcg ctgtacgaat tgccaaggca tcctttagat
    14041 taagagcgat tctcttagga tataattccc caaaaacgat ggaaatatag gtcaaaaatg
    14101 ccaaggatag aaaagttgcc acggcttgtg ctgtttcgcc attcccaagc caagaggcaa
    14161 tcacacgtcc tagagtatca gttaaactcg cccctgataa gattgtaatc agagtgattc
    14221 ctacctgaat ggttgataaa aagtggttag gattttctag taccttcagc aggcgaatgt
    14281 agcgtctgtc tccttcttcc gccttttgtt caactcgggc acgattaaga gaaaccatgg
    14341 ccatttctgt ggctgagaaa aaggcattta ataccgtcaa gataaacaat aaaacaaatt
    14401 gtagcaacaa attctgacta cttgggtctt ccatagttct tctcctaaaa tagtatctta
    14461 tcctttatta tatcacaaaa tttaatccaa tacatattat ttttttctta gcgtaacttc
    14521 catctctctc ccaaaactgg aagttagtct aagacggatt tccactgatt tcacgcgttt
    14581 ttctcatact aaaagctagg ttgtgggaaa ctggaagtta gttttagaag ttactatttt
    14641 ttcttagtac ctgttctagc cctgcttaaa ctagtaaaaa gaactcctac atccataagt
    14701 gacataggag tttaggctta tcttttactg agttacagtt acttctccag ttcggtaatc
    14761 cagttgaagt cccttttgaa cattgggaac tagaacattg aattccaatt ctccatccga
    14821 agacttggct tcaatctgtg aagctgaggg aactaaatcc tcgtttgaag cgtagtaaag
    14881 ggttacacgg taacggacac gcttgttttg gtccaaggct ttacgcacct tgctttcata
    14941 gtagttttga ccagtcgaat actcggcttg tgcctgattt gcccaggctg tctgaacagc
    15001 aatgttttta ggattgcttg ttgaggcatc aaaaccatcc aaaccaccga ttaaggcata
    15061 gcctaacaaa tgacctctat cgactgcatg ggtataagag ccctttagat tcttgacctg
    15121 atgccaacct ggaggagtcc aagaagttga accattccca gtttcttcac gattcttgta
    15181 ctgacgagtg gccttagaca agagggcatt agctacggtt ggaacagttt ccttgcccac
    15241 tgtctttgtt ttattgtcag cgtagggctt acttgaaacc ttggcatcta gatttgtttt
    15301 attaccattg acgataaaag cacctgagcc attccactcc agactcccct ttatttgact
    15361 cttgactgcg tctgttaaga cactttctgc caattcttga ctaggagctt caggcgcttg
    15421 ttttttctga ctcatttttg tcttagcagc ctgatttcct agttcattct gcttaatata
    15481 atagctccct gcagacaaaa gcaataacac tagcagtcca atcagtgtct gtcttgtttt
    15541 tttgttcata tttctcctta tctttagaaa aaggctggtc tcccagccta atttcctgta
    15601 aatttatgaa tcaattcctg ccattttgcc ggagacagga tagcccacgg atcttgaccc
    15661 ttgcccaaga ttccatagcc taccattaaa ccgattccta aggctagaag gcctaaaatc
    15721 agtaccagaa tgactaaaag taaacgcttg attacgtaac ctgatttctt attcatcttc
    15781 atcatttgcc tcaatccgct gaatcttagc acctagctgc gccaacttct catggaaacc
    15841 gtagtaacct ctatccaagt gaaccaattt accgaccaca gtttctccct gtgctaccaa
    15901 acctgtcaaa atcaaggccg cactggcacg aaggtcagtt gaaagaactt ctgctccctg
    15961 caaaggctgt ccaccaacaa tacgagctgt atcacggata atctcagaat gcaagcccat
    16021 gcggcgcatc tcttctaggt gttggaaacg attttcaaaa actgtctcca ccatggttga
    16081 ttcgcctttt gcaactgtca tcaaggctgt aaattgagcc tgcatatctg ttggaaatcc
    16141 tgggtggggc aaggttttca catgaacagc ttttagattt tctagttgag aacgaacacg
    16201 aattccttcg tcttcttcaa ttacttcaac acccatttca agtaacttgg caatcaaggg
    16261 acggttgtgc tcccagacag cgtctcgaat caagacatca ccaccagtca tggcagcagc
    16321 taccataaag gttcctgctt cgatacggtc ttggactaca ttgtgagtcg taccatgaag
    16381 tttctcaaca ccagtaatgg ttatagtctc tgtaccagca cctttgacct tggctcccat
    16441 ttcattaagg agaatggcta agtcaacaat ctcaggctca cgcgcagcat tctcaatcac
    16501 tgtcacccca tcagccagag tcgctgccat catcaagttc tgcgttgcac caacacttgg
    16561 aaagtccata tagatatgag cgccatgcaa gcgttctgcc ttggcttcga tgtaaccagc
    16621 tgtctgacta atcttaaccc ccatagcttc cagacctttc aaatgaagat caataggacg
    16681 gctaccaatc gtacaaccac ctggcatgga taccttggca tgacccacac gggcaaggat
    16741 tggccctaat acaacgatgg aggcgcgcat cttgctgaca tacttgtaag gggcttcctc
    16801 agtgatgtcg ccagtagcat ccaccttgac aagatgagct tcctcatcaa agtcaacctt
    16861 ggcattcaaa ccaccaacta cctgattcat aataaagaca tccgacaaaa tcggaacatt
    16921 ctgcaagacg gtctttcctt cacttgctag aatagtcgct gccaacaagg gtaagactgc
    16981 attttttgct ccctcgatcg tcacgcttcc taccagacga ttatcgccac cttgaaccac
    17041 aattttatcc atactcgttt cctttactct tgatttcata ataatcctct aagcgcttct
    17101 tgccacaaat gatacaggct aataaagaaa gaactcagga tgtagcctat gacaatgcta
    17161 aaaaaggcta ctaataaacg aacttttctt gtattatcat ctgtcacttt taaaaccttc
    17221 tcccatctaa caagatcctt taaaaggtaa aaactcacat aaataaagag catatgacta
    17281 cttagagtga ataataattg aaccatttga ctattatacc atcttctctg tttgtgcgct
    17341 agtttggaaa cttcactcaa aaattaggga ttgtttttca agtaatcaat cgcatcttgt
    17401 agggttttaa cgggcacgat tttcatatcc gtcttgattg ttttagccgc ttctagggct
    17461 gtttggtagt tgtttttcgc gtccggatgc gccttttgtt cttcttcgct aacagggtta
    17521 tcaggagcaa agaaaatagc agcatctgcc ctagccgaag ctacaacctt cttatcaata
    17581 cctccaatgt ctcccacatt accatcgcgg tcaatggtac ctgtaccggc aacaatacga
    17641 ccattacgaa gatctgggtg agctatttga gtatagatag ctagactaaa catgagacca
    17701 gcacttgggc cgccaatacc agctgttgaa aagctaattg ggacattgct gattacctct
    17761 gtacgatcaa tcaagccgat tccaatccca ttttttccat tttccaaggt gataatcttt
    17821 ccttctgcag acttggtttg cccatcctct tcataggtga ccttgacgga gtcccctaat
    17881 ttttgagaac tgacgtaatc aatcaagtct ttggaactat caaaggtctg atcattgact
    17941 gctgtgactg tatcagagat attgagaatc cctttaaagg ttgaattatc cgtcacattc
    18001 aaaacataaa ctccaaagta cttgagttcg atatccttac cagctgtttt tagtccttga
    18061 tacttggcca tattttgcga tgtttgcatg tagaattgat tgattcgcat aaattcaaca
    18121 tcggaagaac cacctgtagt ctcctgagca ctacgaatat ctgtaaaagg tgtcaaccaa
    18181 gcataaatca tatgagctaa agtagcatgt tgaacaccaa ccgtaacgaa ttgataggca
    18241 ccagcttcct tatcttctgt gtcatttact ttaaggactt ggcgaatatc ttccgaacca
    18301 cctggaacct ctatatagta gggcaaaggc accacaaatg ccaagaaggt cacaatcaag
    18361 gccgcaatga catacaaggg ccatctaatc ttttttttca tttcttattt cctccaaaat
    18421 actctcggga acatggcagg caatatcctg accaaacttc aaaagctctc gaacacctga
    18481 tgaactgata tagagatgtt caggccggct atgtaaataa atagtctcta tatcagaaga
    18541 cagctgatga ttgtagtaat caaaactagc ttcatattgc aaatccgccg cattcctcaa
    18601 cccccgtact aggaaagtag cccccagtct ttttgcaaca tcgaccacca atttatcatg
    18661 agaagccacg acttcaacat tttccaaatg tcccaaagcc ttttctagcc cccgtttacg
    18721 attttcaaga gggagaaatc cttgtttgtg gggattaaaa aaaataccca cataaagctt
    18781 atcaaaaagt ctgctcgccc gttcaatgat atccagatgc ccatttgtca tcggatcaaa
    18841 tgagcctgtg aataagccaa tcttatctga catagactgt caccttacta attccataaa
    18901 tcttttcctt ccagataccc agacaggcaa tttcttctgg aagttcaacg gctttatccg
    18961 tctcgcacac aaccataaca tcttcagaaa aaagctctct ctcagccatt ttttcaatat
    19021 ctgctacgat ttgttccttg gcatagggag ggtctaagaa aacgaggtca aattccccag
    19081 atacctgttc caatgccctt tctgcatcca ttttgaggag ttgaaatttt ccaacttcct
    19141 tggtcatctg gatattttca gccacgatgg tctgagcctt acggtctcgc tccaccaaaa
    19201 cagcactgga catgccacgc gatactgctt cgatagataa accaccacta cctgcataaa
    19261 ggtccaagac tcgtccccct tcaaagtagg gaccaatcat gttaaaaatg gctcccctaa
    19321 ccttatccga agtaggtctt gttgtcttgc cttctagtgt cttaagggga cgtcccccat
    19381 agattcctga tatgattttc atactgttta ttataccaaa ttatagacaa aaagagaaag
    19441 aaaaccgaac cttgcggttc gattctctac aaaatatttt cgtaagtatc gcggacttct
    19501 tgaggccaaa cacttgtttg cacttctccg atgtgtctct tgcgaagtag gaacatggcc
    19561 atacgagatt gtccaattcc tccaccgatt gtcaatggga ataggccatt caacaaagac
    19621 ttgtgccatt ccaattccaa gcggtcttca tcacctgtaa tttccacctg acgtctaaga
    19681 gtttcttcat ctacacgaat tcccatagaa gacaactcaa aggctccacc taaagactca
    19741 ttccagacaa gaatatcacc atttagaccc ttgtagccat tctcagactc gcttgtccag
    19801 tcatcatagt ctggtgcacg tccatcgtgc ggtttaccat ctggcaactc gccaccgata
    19861 ccaatcaaaa agacggctcc aaattcttta caaatcgcat tttcacgttc tttcggtgtc
    19921 aagtctgggt agcgttctac caattcttct gtatggataa aggtgatttg ttttggcaag
    19981 atagactcga tgtcatagcg ggcttcaaca gctagctcag tcaggcgaat agccttataa
    20041 atcttctcaa ctgtttcttt tagataaacg atgttacgct taccatttgg gataaccttc
    20101 tcccagtccc actggtcaac ataaacagag tgggttgcat ccaaggaatc ctcatctgga
    20161 cgaagggctt tcatgtggac aaagagaccc tctccttcac caaagccaaa acgagccaag
    20221 gtgtggcgtt tccatttagc aagtgagtgc accacttcat aagtagcatc agggatttgg
    20281 agaaccttga ccgatactgg attttccaca ccagacaggt tgtcctgcat tccgtcaccg
    20341 accttactca agataggacc ttgaacttcg acaacttcta gcttatcttt caaatactgg
    20401 gtaaaagtgt ttttgacaaa ggaaatttct tcttgttgat ggataaaact tttcttcata
    20461 gacaactcct caaaaattta ataaacgtat tatacaccta tttccaagaa aagaaaagag
    20521 aaaatttaaa aaaaaatcag tgtcactcaa aacactgatt tcatagacct tttagtcatt
    20581 gcgaccaaag atacgtagaa tacttaggaa aagattgata aaatcaagat agatgctgag
    20641 agccattgac accacccagc ctgtcgctac acgaccttgt gattgttcat aggcgaggcg
    20701 aatcttttgg ttatcccaag caatcaaccc tgaaaaaacc aaaaccatgg ctacgctaat
    20761 catataatca aagaagccac tagccaagaa aatattgact accatagcaa tcagtaaacc
    20821 aatgagagct gccatcattg ctcgaccaat cccactcaag tctttcttgg taaagatacc
    20881 aactgccgcc atgacaaaga agagaagggc gctcgataca aaggcagata aaactgtacc
    20941 cggagtatag aaagccacca caaaactaag ggtaaagccg tttaaaacgg agtaaagtaa
    21001 aaatactgga agagcagctg gactatttct tgaagccata ctactggcaa cgaaaaccaa
    21061 agccaactcc gcaaaagtag caatggtcaa ccagagacgc ccctgcatca acaagtaaac
    21121 caactgagac tgaaagaccg tcaacataag gcctgatacc aaagcagata gtccgattcc
    21181 cagaccaaca aaggcataaa ccttagcgta aaattgattg agacctgcac ggtcatgtat
    21241 aatagtgtga ttcatccttt tctccttttc tgtgaacatc tttccttgat tataacaaaa
    21301 aaagttaaaa ttagcttaaa tggaagatta aaataccggc tgcaactgca acattcaaac
    21361 tctcggcctg ccccttcatg ctaatatgga ccaactggtc tgcactttca gccataaggg
    21421 gactaattcc ttgaccctca tttcccataa ctagtacaaa attttctata gaaggcagtt
    21481 ctctgtaatc aacagaatct ttagataggg ttgttgctag cactgggata gctacctttt
    21541 tagtttcgtc aagaagcgct tgactagtca tccggtaaat gggcagatgg aaatgactac
    21601 cttgcatgga acgtagggtt ttgagactgt agatgtctgc cgacttatct gaaacaatca
    21661 ctcctgtaaa acctgctgca tccgcagttc gaatgatagt tcctacatta ccaggatctt
    21721 gcacatcttc caaaaacaag aacttgccct gactcaaatc agcttgtcct acttcttctt
    21781 tttgaaccac cgccacaatt ccctgtggag tctgagaatc cgccaaatct agcaaaatat
    21841 cctctgaaat ccagacagtt tgcggaaaag cagctaactg atctcgataa ttttctaggg
    21901 caaagatttt ctcaatcgtc actccagctt ggacagcctc ttcaaacaag tgccagcctt
    21961 caatcaaata ggcagacttg cggtattttt tttggtgtaa tttcttggca ttttttacca
    22021 cagaattggc ttttgaggtt ataatagtca tagaaatatt ataacacaat caaaggggtt
    22081 tggtatgcaa aaggttagaa tgattgccca aggtagggta cagggagtcg gctttcgttg
    22141 gggtgtttac agcttggcac ttgaaattgg tggcatcaca ggtcgagtat ggaataacga
    22201 cgatggcaca gtggaaatct tagcccaagc agactcatct gctatcatgg caaaatttat
    22261 ccaagaaatc cgaaaaggac cgacaccttt ttcaaaagta agctacttag atgtcaaact
    22321 aagcaacttt cctccctact ctgactttaa aatcgcaaat taggtctcca gaactattgt
    22381 atattttgta aaaaaacagt agaatagaaa ggtataattt ttaaagaagg aataaaaaca
    22441 gtgaaatcta ttaaacgttt tgcattctcg gctatgggag tggctatgtt gcttgtcttg
    22501 actggctgtg tcaatgtcga taaaaccaca ggtcagccaa caggatttat ttggaatacc
    22561 atcggagcgc ctatggctga agccatcaag tacttcgcta ctgataaagg tctaggcttt
    22621 ggtgtcgcta tcattatcgt aaccattatc gtacgcttga ttatcttacc acttggtatc
    22681 taccaatcat ggaaggcaac gcttcactct gaaaagatga acgccctcaa gcacgtcctt
    22741 gagccacacc aaacgcgtct caaagaagcg actactcaag aagaaaaact cgaagcccaa
    22801 caagctctct ttgctgctca aaaagagcac ggtatcagca tgtttggcgg tgtaggatgt
    22861 ttccctctcc tccttcaaat gcctttcttc tctgctatct actttgctgc ccaacatact
    22921 gaaggggttg ctcaagcaag ctacctaggc attcctctag gttctccaag tatgattttg
    22981 gttgcctgtg ctggtgtcct ttactatctt caatcgctcc tttcacttca cggagtagaa
    23041 gatgaaatgc aaagagaaca aatcaagaaa atgatttaca tgagcccact catgatcgtc
    23101 gtcttctccc tcttctcacc agctagtgtc acactttact gggttgtcgg tggtttcatg
    23161 atgattctcc aacagtttat cgtcaactat atcgttcgtc caaaacttcg caaaaaagtc
    23221 cgtgaagaac tggcaaagaa cccaccaaaa gcaagtgctt tctcaacacc aagtggacga
    23281 aaagacgtta cccctgaaca accaactgct attacaagca agaaaaaaca caaaaatcgc
    23341 aacgctggaa aacaacgttc gagataagaa gaaaaaggct tagctgattt gctaagtctt
    23401 tttgcaagtc aaaagcccga tgtttccatc aggcttcttt tctatccatg tacacgtttc
    23461 atataatctt gataactttc ggtatccatg agttgtttag cgttcttgac gcgatctgct
    23521 gttggtggtt tgactccttc gagggaatat ggaattccaa gttcacgcca cttgaactca
    23581 cccatggtgt gataaggtag aatttcaaac ttatcaacat ttttgagggt cttgacgaac
    23641 ttaccaagtt caatcaagtc atcatctctg tctgtcaatc ctggaactag cacgtggcga
    23701 atccagacag gttttccaat atctgataga tactgggcac aagccaagat atttttattg
    23761 gtttggctag tgacaatctt gtgctgttct tcgttgattt ccttgatatc caaaagaacc
    23821 aagtcagtga cagccatgag tttgtcaaac ttctcaaggt aacgtggttt attacggaaa
    23881 ggaagagcac aagtgtccaa ggtacagtgg attccttgtt ccttagcctt ggtgaagagg
    23941 gcaatcagga aatcaatctg caagagagct tctcctccac tgactgtaat cccaccctta
    24001 tttccccaga aaccacggta gcgcaaggcc tctgtcaaga catcatctac cgtccgttca
    24061 cgtgacttat tggactccat agcccaagtg tctgggttgt ggcaatactg gcaacgcatg
    24121 tgacagccct gcaaaaagac aataaagcga ataccgggcc catctactga cccaaagctt
    24181 tctgtcgaat gcaccattcc tgtcacttgt ccataatcaa ttgtttcttc agacatatcg
    24241 ttaccttcct tgaaaacgtt ttatagtttt attatatcac gacttgaagg aaaaacaaga
    24301 tttttgccta ttttttagaa agcaatctgt ttttcaattt cattttcaat ctattatcag
    24361 attattcttc aaaatcgaag ccatataagg ttgcaaaata gtcctcaggg cgctctgcac
    24421 ggcggatttg acgggcttta ccttcttcgg tatagaggat ttccgcagaa cgtaatttgg
    24481 cattatactg gtagcccatt gaaaatccgt gggcacctgt atcatgaatt accagcaaat
    24541 caccgatttc tgtatgaggc agttcgcgat tgactgcaaa tttatcattg ttttcacaga
    24601 gtgaaccaac cacatctacc gcttcagctg gtccatctgg atgggtcacg ttgctaatat
    24661 gatggtaagc tccgtacata gctggacgca tgaggttgac tgctgaggca tctacaccta
    24721 gataggtacg gtaggtttcc ttcttatgag tgactcttgt gactagagca ccgtgaggtg
    24781 ccagcataaa acgacccaat tcggtgaaaa tcttgacctg accaagacct gctgacgtaa
    24841 gaacttcttc atacacctta cgaactccct caccaatcaa ggcgatatcg ttcggctcct
    24901 ggtctggacg ataattaaca ccaataccgc cagaaagatt gataaagtct aacgaaatgc
    24961 ccaacttttc cttgatttca acagccagtt caaagagctg acgagccaac tctggataat
    25021 agagatgggt cacggtattg gacgctagga aggagtgaag cccaaaagtc ttggctcctt
    25081 tttccttcaa gatagcaaag gcttcaaaga gctggtcctt ggtcatgcca aacttagcct
    25141 ccccaggatt gtccataatg tctgtcccca gttcaaaaac gcctccagga ttataacgac
    25201 aagagatgat ttctggaatg cctgctactc tctccagatg ttcaatatct tcaaaggcat
    25261 ccaagttaat ggtcgcaccc aattcacgtg cataggcgta ttccttgtct ggcgtgttgt
    25321 tggaagagaa cataatctca gaacccagaa agtccagttt atggctcatc aaaagctcta
    25381 cataactaga gcagtccaca ccacaacctt cttcttggag aattttcaaa atagctggag
    25441 ttggagtagc cttaactgca aaatattcct taaagccctt gttccacgaa aaagcttggt
    25501 tgacagctct tgccttctca cgaatcccct tctcatcata caagtgaaag ggagtcggga
    25561 actcggcaac aatcgcttct aactcttctc tattgataaa tggtgttttc ataagcttcc
    25621 ttctattctg tttgcaaaga aaggctggga caatcgttcc aacctttagt tctatctctt
    25681 atttatcttc gtcaaagata ttgccaacct caacatcgat ggcttggttc ttgacatcaa
    25741 tattagttac cttcaagagt gacttgtagt caaactgctt ttcacgttct tcttgggcat
    25801 tgtccgcaaa gaccgctaca cctgccagtt ctgagtcgaa ctcgcgcaag agactaatca
    25861 taccgttgac cgttccgcca cctttcaaga agtcatccac aatcaagaca cggctgcctg
    25921 ccttaagact acgttttgaa aggaacattt tctcgatacg gtcaccactt gaacctgaaa
    25981 catagttgac gctaacagtt gaaccttcgg taattttcag gtcacggcgc acaatgacaa
    26041 aagagacatt gaggacattg gcaactgcat ttgcaagtgg cacaccctta gttgctacgg
    26101 tcataaccgc gtcaattttt tggtccataa agcttttggc aataatacga ccaatatttt
    26161 tcaagatggc tggtgtgcta agcaaatcag acagatagat ataaccacct ggcaagatac
    26221 ggtcactttc tgacaacttg gtacgcaagt cttcaaccat ttccttagca tcctgactcg
    26281 aaatagacgg tgtgaagatg acacctccgc cagccccagt cactgtctgg atatgaccga
    26341 tttcaatttc ctcaaaggcg cgtttgataa tgacgatatc ttctgagatg gatgatttag
    26401 cagactcata cttttcagca aaagtattga gactagttag tttataagga ttattaatca
    26461 aatagttgga aatgacaacc atccgatcac ttcttcttaa tttcatttct atttcctatt
    26521 ccatttttat tcaaaaaatc aaaaagcaaa ctagaaagct ggtcgctggt ggttcaaaac
    26581 actgttttga gattgtcaat agaactgaca aaccctgtaa tatacctgca tatatacata
    26641 cgacaaagcg atactaccct agtttgaaga gattttcgaa gagtattcat ttttgtcttt
    26701 tacttattat accatattca cataaaaaaa cgaacattct tatcctaaaa aatgctcatt
    26761 tttcttaaat tatcaatcta aatctggttt atagaaggaa cgattatcca tagcgaagat
    26821 tttattggac atctctcctt tatccaccaa agccagagct gttgacatca tcatcatgct
    26881 tgcatccaga ttgtcaatca tatggataat ctctgcctcc ataatacgtg gacggactgg
    26941 acttccatat tcaagcaagc cgtggtgact gaggatgaca tgacgaagca aaacgacttc
    27001 ttccttggta tcatcgatgc cgagttccat aactgtcttg gtaatttcgc tatcaatgag
    27061 agcgatatgt ccaagaagat tacctcgcac tgtgtactct gtctggtctg gccccgtcaa
    27121 ctcgataacc ttagctaagt catgcagcat aatccccgca tagagtaagc tcttattgag
    27181 ctgaggataa acttcgctaa tagcgtctgc caaacgtacc atggtcgccg tatgataagc
    27241 caagcccgtt tcaaaggcat ggtggttggt cttggcagct ggataggagt agaattcctt
    27301 atcatacttg gtgtagagat ttcggacaat ccgttgccag acaggatttt caattttgaa
    27361 aatcatttgc gacatgtagt cacgaatttc cttgacatca actggtgact tgaccttgaa
    27421 atcggctggg tcattgggtt caccagcttg aggcaggcgg agagtaattt gattgacttg
    27481 aggggtattg ttataaactt ctcggcgtcc tttcatgtgg acaaccttac ctgcggtaaa
    27541 ggcctcaatg ttatgaggtt gggcatccca gagcttccca tcaatctcgc cactatcatc
    27601 ttggaaggta aaggctaggt agtttttccc agctcgagtt tgcctcaggt cagctgattt
    27661 gattaggtaa aagccttcaa atagctcatc ttttttcatg tgactaatct tcatattctt
    27721 cctcattttc ttgaaaatgg agtagatcaa gcgcaggctc gccttctgac aactcaatgt
    27781 gacggagcgt ccgctcgata gctatggtac gacggtttaa taattcatca atattgccag
    27841 aggcatgttg gagatgtttt tgtgccttga ccagaatacc accaaacttg ccaaactcgg
    27901 tcttgacact ggcaagagtc ttgctgatat ggtcggcact cttttggata ttaagggtct
    27961 tgaaaccaac tgatagggag ttaagaaggg ctgatagggt acttggtcct gcaacgataa
    28021 tctgttcttc ccgtctcaaa tcatcaaaga agaccggatt gcggacgatt tctgagtaga
    28081 gaccttctgt cggaacaaac aaaactccaa aattggtcgt ccgaggtggt gctatgtact
    28141 tgttcctaat atccctagca aaacgcttga cacttgctag gagtgactta cgacagcgtt
    28201 cgatttcatc cttgtcacct acttcatagg cttcttctaa gcggtaataa tctgccagtg
    28261 gaaacttaga gtcaattggt aggtagacgt attcttggtc gccttgtccg ggtaacttga
    28321 tggcatactc cactcgttca ctagagtttt caaccgttgc gtattctcgt tcgtactggg
    28381 caggtgtcat gatgtcttca ataatttgcc ccagttgcaa ttctcccaga atccctcgcg
    28441 tcttggttcc agagagaacc ttgttaagag ctccgacatc acgggcaact gtctgcattt
    28501 ctccaagacc acgattgaca gactccagtt gtttagaaac tgtctcaaag gaagcctgta
    28561 agcgtgtctg caaggtcttt tctagttttt cctcgaccgt ctggcgcatt tgttccaaac
    28621 gttgctcatt tgattcctgc aaggcttgga gacgttggtc tgtcttgtct ctagtttgga
    28681 ggagattatc tgtcatttct tgacggactt gggtcaggcc ttggtgcaat tcaatccgca
    28741 cttcttgcaa acggtcgctg acagccactt ccaaatcttt ttggtctaac tggctggctt
    28801 gtctggcttg gtcaaagcgg taatccaact ggtctgacaa atgatctgcc tgatcctcca
    28861 agctcttact taagtgtttc tcctgcctat cctgtctttg ccaaatcaga aagagaccag
    28921 ctaggttggc aattaataat agaataagta aactttccat cctacctcct gtccttgcta
    28981 tgcagtacga ccacataacc atctgggcaa gtcaccgaca cttccctatc tatatattcg
    29041 ttagaagcgt acactttttt aaagaaaaaa ttctcctctg tcaactcata cttagctcca
    29101 agaatagtca gctggctatc ccgaactggc ataaaggcta gatagtcgta gtctgaacga
    29161 ggttctagct gactggtccc ttctgaacaa taggcaatca aattttgccc atcctcaatt
    29221 tctatttgac gcatataggg tgccaactta ggattgctag gtagaaagac attggccaac
    29281 atatggtcaa tacggccacc caaggcaccg aaaatagtga cctcagcctg aggattttgt
    29341 tcaaagatgg ttaagagagc caattccaga tctgtatcat ccttttctgg tcgggcttgg
    29401 acaaaatgct gggcacgttt ttgaatcacc tgtcgctctt cttccgtcac agaatcaaaa
    29461 tctccgactg ctagagcaag aggtaagtct tcttccaaga cccagagcga gcctcgatcc
    29521 accccaacaa aagcatcaaa atctgtccga taatgaccgc ggtttccgtc tgcaaaaacg
    29581 gcaaccctag tccagttgtt ttctgagagt ttgtactcgc tcattgactt ctcccttaaa
    29641 gacataggaa cctgctacaa aaacagtcgc accagcttct ttggcttgag caatagtttg
    29701 gtcatcaatc ccaccatcca cttcgatttc aaagttcaaa cctttttcct cacgaagagc
    29761 aaccaactca cgaaccttat ccatggtttc tggcagaaag gcttgcccac caaaacctgg
    29821 attaaccgtc atgactaaaa cttggtcaac tagatgaagg acgtgcttga tggcttcaac
    29881 tggtgtgcca ggattgataa cgactgaagg cttaactccg agtaaacgaa ttttttggag
    29941 ggcgccatga atatgaggtg ttgcttctac atggatactg atgatgtctg cacctgcacg
    30001 cgcaaaatct tccagatgat gctcagggtt tgacaccatc aagtggcaat cgaaaaccat
    30061 cttactatga ggacgaaggc tctcgaccac acctgcacca aaactgattt gcggtacaaa
    30121 atgactgtcc atgatatcga tatgggcata ttctgcccca gttgcttcta gacgtttgat
    30181 ttcacgttca aagttggcat aatctgctgc cagaattgac ggagcaatct tgtattgaga
    30241 cataggtttc tccttatttt ggaatttttt tgctgacttt tttataggtt tctctacgat
    30301 tttcaatttc actaaggaat tgcaggtaat tatcaaaacg gaaggttgca ataacaccct
    30361 cttcaacagc tggtttgacg gcacaagacg gctcatgggt atgggtacaa gtacggaact
    30421 tacaatctcg gctaacagta gcaatctctg ggaaagcctg attgaggtct tcagcccttg
    30481 atacttcata gtccagagat gaaaagcctg gtgtatctgc gattttaccc ccgttgagat
    30541 tgtaaaaact aacagctcga gtggtatggc gaccgcgacc tagactgtct gaaatttctc
    30601 ccgtttcaag attgaggtct ggtacgagtt tattgagaag agttgacttc ccaacacctg
    30661 tctgccccat aaagaccgta accttgcctg ttaacaaaga caggagttcc tctttactgg
    30721 tcacaaagtc atagccgatg tcaccatagg tctgccggta aaaatccagt tctcccctat
    30781 cttccaacaa atccattttg gaaatataga caatgggatg gatgcccttg tgctccaaaa
    30841 gaaccaagaa acgatccagc aaattgctgt taaaatcagg ttccttgacg gacatgatta
    30901 ctacagcttg atcgatattg acaataggcg gacggaccag actgtttttc cgttcgtgaa
    30961 ttttgaggat atagccttct gaattttcct cggcagagaa atctacccag tccccaacat
    31021 aaggggtatg gcctttttta cggaaattcc cacgcgcgcg tgtttgataa acctggccat
    31081 cactctccac atagtagaaa cctgccaagg ctttaatgat ttgtccctgc atcttagagt
    31141 ccttgccctt taagtgcgtc tgctagaccg gcaaattctg ccaagctgag agcttcccca
    31201 cgcacacttg gtgacaagcc tgcctggtcc aaagccttgg tcagcttgtc cttgacctct
    31261 tcagtcttac caaagtaacc tgtcaagtta ttccacaagg tcttgcggcg atgggtaaaa
    31321 ctagccttgg aaaccttaaa gaaaaagttc tcatcttcta ctgctacggc tggctctgga
    31381 cgacgcacca ttttcaagat ggctgaatcc acatttggcg ctggcacaaa gaccgtacga
    31441 ggcacgataa aggcaacctt ggctgtcatg taatactgca cggcgataga caagctaccg
    31501 taagccttgg tgttaggctg ggctgaaatg cggtccgcta cttctttctg catcatgacc
    31561 acaaactcac aaaaaggaat gccactctca atcaagtgca tgagaatagg cgtcgtgatg
    31621 tagtaaggca aattagccac taccttgatt ggcaggttag gatttttaaa attttggata
    31681 tgttgcgcca aatcaacctt gagaatatct tcgttaacta cagtcacatt atcaaaatca
    31741 cgcagggtat ctaccaaaat tggcaccaaa cggtggtcaa tctcaaaagc catgacttgg
    31801 gctgcacgct cagccagaaa ctccgtcaag gcaccaatac ctggcccgat ttcgatgaca
    31861 ttgacctggt catcaatttc agccgtatcc acaatttttt gaaggatatt ggtatccgtc
    31921 aggaaatttt gcccgaagga ctttttaaag gtaaaaccgt gacgctccag cactgccttg
    31981 gtcacgctat aatctgcaat tctcatctat tctcttttct attatctgtt actactattg
    32041 taacacattc cccttgtatt ttgggaatga aaatcatacc aaaaaactat ctttcctcat
    32101 gaagaaagat agtcttggaa atctttaaaa gtggccttaa cagttctctc gaaacatgcg
    32161 ttcaaaaaaa tcagcttctt gataacttcg attttcaggt agggtcaaat ccacatcctc
    32221 ctccacatca tccactgtca gttcaaccgt ctgaggtaaa tttttcaaac gataatgctt
    32281 ttgcctttgc ccttcaatac tagcaaaatc aagcaaatag ccatgcactc ggatttgaac
    32341 caaaaggaga tgattggtca tattttccat gatgaggata tcttctaaac cacctctggc
    32401 actaggataa tcagataccc tgcgaatacg gattttttca cacatgagca agtttcctca
    32461 tatcaatgat ttcatcagcc ttattccaga ctaggggatt atgggtcgca atgatgataa
    32521 ttcgattttc atctttcaaa tccaccaaga gattcataac ctcctctgaa ttttcaggat
    32581 caagagctgc tgttggttca tctgccaaaa tcaagggtgg atttttcaaa atagtcttag
    32641 caagggcaac tcgttgggcc tctcccccag ataaagtata gattttttgt tctaaatcca
    32701 aataccctag attaactttt tctaaagccc ccacttgcct ttccaaacgt tctacttttg
    32761 agattttctg accaacaaaa cccaaatcca aattttcttt gattgattgg ttttctaaga
    32821 ggccgaaatt ttgaaagaga tagcccatct ggtctcgaaa atactcacga gtgggaatgg
    32881 tttttaaatc tttcccctga tagagaaccc ttccaccatc tatcttttct agctttccca
    32941 agatattcag cagcgtcgtc tttccgcttc cactctttcc gattaaggca taaaccttgc
    33001 ccttctccag cttgagattc aaaccagaga aaatcgcgcg gtcattaaat ttcttttcca
    33061 atccttgaat atcaatcatc ttattttcct ttcaatactg ccatgctacc agcttcttct
    33121 tttttgtcct gccttactaa aatcaagagg gcgttaagcg taaacaaagc tacaactaga
    33181 gcgctaatca aaccatctct tgtcaaaata ctagatagga ctaagccaag caagagaact
    33241 cctccttgcg ccagtaaata cttgccatga agctcataga ttgtcatacc agcaagacgt
    33301 ttaatcataa gctcccgtct gaactgctca aaatagagaa gattcatgga atcaaataac
    33361 aagatagccg tagacagggt caaaatcgtc ccaataagga gagagtaaaa ctccacccgt
    33421 ttgtcattta gtaccttggc aaaaaatagc tggcttttta ccaagtaaga aaccttgtga
    33481 tacagacctt gctcttttag agctgtgatg ctgtctccat atcgatctag tttcaaggca
    33541 ctattagccg tagttcccca caacatccct gcaacaggtc ttgttccagt cgcttgcggc
    33601 gttagaacta caataatcgg atcttttagg tactggcgtg ttgtcttgta cccatcatta
    33661 tagaggaaac gttcctgtcc tgtttctgta aaagctagcc ttacctgtgg gaggtagtgt
    33721 ttctgactcg tcacttctac actttcagat gaaaaatttt gcaggtaatc tgtaaacaat
    33781 ccttggtagt agacagactg ctctcgcaag ctctcaggca agatcagccc aaactctccc
    33841 tcagacaagt tttgcatctt gtccataaac tctgaagaaa cggtaatctt ttcttctatc
    33901 agatagcgtg gtgagacata gataacattc cctgacggtg tgtagtcact gagacgattg
    33961 ccatctaggt ccacttctgc tccatctgag aaattgtcaa cattgctcat aatataaaaa
    34021 gagtctgtat tggctaaccg ttcttcagta aatgtctgcc actcacgatt atccttacgc
    34081 gttccttctt catcggcaaa tgcactagac caaccaaagg atagacggta acggtctgag
    34141 gactggctcc atttattgct agctctctcc atttcctgca tttcacggta gtggggtagg
    34201 agagctgtcg cactcgatcc gaccaccaat acagctaaga gttgccccac catcatcaat
    34261 gtcatcatac gtttgagagg gagtttccct ttcaatagat ccaccagact attttcctgt
    34321 aaaccaagta gatggacgac acttagtaag gtagaaatcc ctgccaaggt caatccatag
    34381 agtagaagag caatgatgac cagttgcacc gttgccataa acaaggcacc ttgataccag
    34441 agaatcccca atcccaaaag actggatacc agcactgagc agataagctg tctcacatct
    34501 tctaacactg gtctgagagc aactccaaac aagctctcac cagctattaa gcgaatccct
    34561 gcttgacgaa gggattttat ccgataaatc agggtcagac tcataaaggt cagcagaaaa
    34621 atagctaaac tcagtagcac cataggggtg gccgtcaata gtaagactat cgaaaatgga
    34681 tcttctccat tcgaaacaaa gccttgatag ccaagttctt tcaaggtggt ctgtaagctc
    34741 actccatcca aacttcctga cacaatcaag taagacccta ataaatcact cgtttctgca
    34801 ctctccttgg aggaaatggt cagaccttct ggaagctctc cctcaccata agttgcatag
    34861 gtaaagcgtg tttctccagc ttcatttggc tcaacgattc gacgggcgat gagactatta
    34921 tgctctaccg ccaagtgact caaagcctct gtcacctctt cgcgactagc tactggttga
    34981 tttgtcatca ttcctgtcac atcaacagaa ggatagttac caaataaaat ctcttctcga
    35041 tggtcaacgg aagttatcac catataaagc gataccaata ccattgaaat caaaataaat
    35101 aaacgtttca tcatttcctc caaaaagtta cttggtcact tagtgagaag gtgaccaagt
    35161 aaagctaaac aatagggcta taccattcta aacattatag tagaatgcaa ctttctctcc
    35221 ccaagaagta cgaatccatg cacgagaagt ccctccagca ccagcatatc ccttgtcaga
    35281 tgaaccagtt tttctgctaa caactgttga actatggtat tttgaagggt gatagtagtt
    35341 tgagtaagca ccaccgttac ctgaaccata agtccaaaca ccaccttctg ggtattgaac
    35401 ggctgcagag gcaactgcta cacttccacc taatgttgct gcaatgctcg ctacaagagc
    35461 taatttttta actgtttgtt tcatattgat actcctctat ttttgattac aagattgttg
    35521 agttacttgc tcctctttcc attatcaacg ttgatactat tatattacca aatgatattc
    35581 taaaattatt tgtttttctc taaattgtca aaatagcacc ctgaaatgaa cttttatagt
    35641 cattatactc catctttatc acactatcaa ggacatcaat gtccttaaaa tctaactatt
    35701 tcatattatt tttagcctat atctaaaaaa acagttctaa agacgaactt tagaactgtt
    35761 ttgatacgag gacaaggaca tttttgtcac tgattcacta tgtttataaa tattttttga
    35821 catcctcttg ccattcctct gtcaatttct ttactagaaa ttcatctcca attagctgcg
    35881 caaatgtttt agaagactga taaaatgatt cagctaaact aaaatctctt tcttctctta
    35941 atgcttgctt ccacaaaaac ataaatacaa gaggtttctt ttgataatct tgagttttat
    36001 ccataatttc ttgtaaacac gatagataat cattaaaaca atcagttact cctacctttt
    36061 caagacaaca cattcctgaa ataagagtat ctctaattat aaagaagttt tctaatttag
    36121 ttaccttttt ctgttccaaa agaaagagca ttagcttttc gatttgattt ataaatttgg
    36181 caagatcttt tctaatgagc atttgataaa aaaacaaacg aatcaacaac atatcatttg
    36241 ttgaataaac ttctttttct atgatctgag acatatgttc ctcaagtatt aactctgcat
    36301 attcaggcct tctagttcta gaagtatcca aacacgcctg caatacttca catgctaatt
    36361 gttcttcttt aggaagatta tcaaagtatg ttttataaat ctcttccaaa cacgcttcct
    36421 tcttatcgta ctcctcttct ttaccataga ttggttcacg taaaatctgg tatttcaatt
    36481 ctaaataagc aggaggaaga gctgaaaaat ccggcataag gctataaact ggaactccta
    36541 gccggcgagc aatataggct aacttgggca aactcggttg cgaagctcca ctttcaattc
    36601 gcgacagttg acgaactgtc agttcttgct catctccaca aaaatctgga cgactaactc
    36661 ctttttctat ccgaatctct ttaatttttt gaccaattaa catcagacgc ctcctcttct
    36721 acctgcttcg aaaaatactg tgaaacttaa aaaattgtaa cggtcacatc tttcctactc
    36781 ataagatttc atagcttctt ccacttctgc caaagtaacc ccaaacaact ctaggcgttt
    36841 gaggagttgc ttgccgttag aatagccgat tcggagagtc tctccgagat attccctacg
    36901 cttacggctg tctgccccta ctagaaaacc aaggcgaatc aagtcgctac gactaatgtc
    36961 aaactgactc tcatgttcaa attgttctgt cacctgagct agagccgttt tcaggtcttc
    37021 atagctggca tgctcaattc ccagagaacg ccccttggtc ttggacttgg gaacagcttc
    37081 atctcgcttg agaaaggcat gctgaactgt tggaatgacc gtcatgatca tgcgccgaat
    37141 ccgttcccca ttaaaatctg ggtctgtaaa gacaatgact ccatgacgtt ggtgcaggcg
    37201 ctgaatccgc tctatatcct gatcattgat ggcagaacct cgagtctcat aggtctccac
    37261 atcgaaataa cgtttgagat tgaccgtatc atcacgccct tcaaccacaa ttacttggga
    37321 aattttctct ttcattactt gctgtccagt ccaaaaattc gttctgcatt tgcagtcgtt
    37381 gctaccgcca gctcttctgt cgtcatacca cgcaagtcag cgataaagtc gaccacatag
    37441 cgagtatagg ctgttttatt ttcacgacca cgcttgggta caggtgctaa gtaaggcgca
    37501 tctgtttcca ccaacatctt gtccaaaggt aactctttag ctgcttcttg gaggtcagtt
    37561 gccttcttaa aagtcaccac tcctgagaag gaaatggtca taccaagatc cacaaacttc
    37621 tctgcccact caagcgtccc tgaaaatgaa tgcatgatac caccacgagg accaacgccc
    37681 tcactcttga taatctcata ggtatcttcc agcgcatcac gggtatggac aacaaaaggc
    37741 aaatccaagt ccttagatag ctgaatctga cggcgaaaaa cctgctcctg cacctctttg
    37801 ggcgctgtca tccaatggta atctaagcca atttcaccta aagccacaac cttgggatgt
    37861 tttaacttat ccaacaagta agcctcaact tcctctgtat aagtaccagc ttctgtagga
    37921 tgccaaccaa tagtcgcata gagctgctca tactcatcta ccaactccaa ggcacgctca
    37981 atcgtcggtt tatcaaaacc aacaatattc atctgtgtca cacccatctc agcagccaag
    38041 gcaatttctt ctgcctcacg acctgcaaat tcttctacat tcaagtgtgt atgtgtatca
    38101 aaaatcatct cttctaacct cgttttctat cttctattat accaaaaaag aggaggggca
    38161 cctaattttt cggtttcccc tcctctcttc aatagagagc tattctgcta tcttttctat
    38221 ccgatattgc ccatctccta ttccacagtt agagacagaa gagattggct acattgatag
    38281 actattccta ttcagctaaa gtatgtgatt atcttgggtt ctcacttttc tcacccatca
    38341 ctaggattga tgacttctca aaatccccct tataatctaa ctttaagtag agaatagaat
    38401 tttctagctg ttccattttc tacgtctagt ctttcttcct agcaaagcaa aaccactggt
    38461 tgccgccact agaccaagac tagcaagtgc tgcacttgat gctgaacctg tgttaggtaa
    38521 ttgtttgcca gcaggtgact ggtaggtaac atcttgcatt gttcctgcag ttgcttgcgg
    38581 tgcacttgtt gtcttaggag cagcattagg agccactggt ctcttaagaa ctgtaaccat
    38641 ggcaatggct tgcactccaa tcgtttctgc ttccttcaca tcttccatag ttttcgtatt
    38701 ttcaatctct ttgagagctg cttgtttttc tgcttccact cttgctaaaa gttctgcttt
    38761 ttctttatca gaaagcggtg cgcctttgat ttcatcctgc ttgtccttgg ctgctttttc
    38821 aatggcattt ttagctgatt ctttttcagt agctaattgc ttagaagctt gtgattgagc
    38881 tgagttttgt gaacctgtgt gagctggtcc acctgcctgg ctaccaccgc ctgcattcgc
    38941 attagcatct gagcttccag tattgcctcc cttatctaca cctagtgtag tttctggctt
    39001 atactctggt gtagcttctt gagttacaga ttcacctttc gcagattgtt gaactgtatc
    39061 ttttcctaga atcgtcacta ctgaaccatc tgggaatgtg attgttgctg taccatctcc
    39121 agctacttca actttatagc aaaatgaaac aataacagga caaatcgatc aggacagtca
    39181 aatcgatttc taacaatgtt ttagaaacag aggtgtacta ttctagtttc aatctactat
    39241 aacatcgctt ccgaatccat ttgcatctac tgaacttttt tacaaaaata aaaatcagta
    39301 gactcgagtt cctactgatt tttgatagaa ttcgtttgga ttatgcagcc aaaactttgc
    39361 gtcctttacg acgacgagct gccaatacgc gacgaccatt tttagttgac atacggttac
    39421 ggaatccgtg tttgcgcgca cgacgaagtt tacttggttg ataagtacgt ttcacgatga
    39481 atacctcctc atagattttg tattcgttta gccggctata aagtgatcag ttactaaaca
    39541 tactttacta ttctatctga ttctttcact tttgtcaata gctctaggca aatgtttcca
    39601 gctttttcga atgcaagccc tatctacgat actgtttcaa gaaacgagtc atcttttctt
    39661 ggatttgggc taactcatca acacgaggaa ggtaaacgat acggaagtgg tctggttcct
    39721 gccagttaaa gcctcgacca tgaaccaaga gaaccttttc ctgcttcaag aaatcaagga
    39781 caaactgctc atcatcatcg atacggtaca tattgcggtc gatttttggg aagatataga
    39841 gccccgcctt gggtttaacg gcagacaaac ctggaatatc ttgaatggca ttatagatga
    39901 aatttctttg ctcgtagatt cgtccaccag gaagaagcaa ttcatcgact gattggtgac
    39961 cccccaagga agtttgtacg acttgttggg ccaaaacgtt agagcaaagg cgcatattgg
    40021 acagcatatt gagcccttcg atatagccct taacatgagt cttagggcca gacaagacca
    40081 tccaacccac acggaaacct gctatgcggt gggattttga cagaccattc atgctgacac
    40141 agaagacatc tggtgccaag ctcgccacag gcgtatgcac atgtccgtcc attaccatgc
    40201 ggtcatagat ttcatccgca aagataatca aatcgttttg acgggcaatc tcaataatct
    40261 ccagcaagag ttccttagga taaagggctc cagttgggtt atttggattg ataaggacaa
    40321 ttgccttggt attggaagtg atttttgact tgatatcgtc aatatctggg taccattcca
    40381 cagcttcatc acagatatag tgaacggcat ttcctccagc taggctgaca gccgccgtcc
    40441 atagaggata gtctggcatt ggcactaaga cctcatcccc attgtccaaa agcccctgca
    40501 tggacatgac aatcaactca ctgacaccat ttccaaggta aatatcatca atatctacgt
    40561 ttgggaattt cttcagctgg caatactgca tgatggcctt acgggctgag aaaatccctt
    40621 tggagtcaga atagccttca ctatcacgcg cattcataat caagtcatga atgacctcgt
    40681 ctggcgctgt aaagccaaat tctgctggat ttcctgtatt cagacgtaaa atcttttctc
    40741 cattcgctcg catccgcatg gcttcttcca atacaggacc acggatatca taagcaacat
    40801 gctctaactt actagacttg ttatattctt tcatcttgtt tcctcaattc atcaggatag
    40861 taacattata ccactagaaa gagaatgcga caagtttact gaaatgtgtt actagtttcg
    40921 tatagaagaa aaaccttgct aaaggcgagg ttaagaacgt agagatagca ggtattttgc
    40981 aaagacacat cacataccaa aagataaacc tagaaaaagc aagcctagaa aggagtcata
    41041 aagaagatta aacatgagga aaagccccca tatcatcaag taatcccaac gcccacttcg
    41101 ttttgcaact agaaataaga ttagatggta gagtacatga aaaactaaaa atccaataaa
    41161 acttggataa agaagcggta ccagactctc taattgacag atcatgatca cttctaccaa
    41221 gactgaaact aggataattc cataataaag gaaatttgat ttttgaaaag agtttttcat
    41281 cattctccct tccttcactt ctttcctgct atcctttctt ttattttatc atatatttat
    41341 atagagttta agccctaata ttcttttgaa aaatactttt tttgctttac ttctatagtg
    41401 aaaaggttta caattatagt aagaaaattt caggaggttt cattatggca caacgttacc
    41461 aaaatatcat ggtcgcaatc gatggttcta aggaagcgga cttggctttt gtcaagggag
    41521 ttcattctgc tctacgaaac gacgctaaac tcaccatcgc acatgtcatt gacacacgcg
    41581 ctctccaaag cgtatccacc tttgatgctg aagtttacga agaactccaa gtcgacgctg
    41641 aaagtctgat gaaagagtac gaaaaacgtg ctaaagatgc tggggtagca gatgttcata
    41701 tcgtcattga aatgggaaat ccaaagaccc tgctagcacg tactattcca gatgccgagg
    41761 aagtggacct catcctcgtt ggcgcaactg gtctcaacgc ctttgaacgc ctcttggtcg
    41821 gctcttcatc tgaatacata ctccgccatg ctaaggtcga tttgctggtt gtgagagaac
    41881 aagaaaaaac cttataatca caaagaaaag gagcccctag ctcctttttg tttacgattt
    41941 atttctctct ttatggcgtt cgtaagcctt gagctggcgc tgcagttcct ttttaatagc
    42001 aggttctgga gcatattttt cttcccaatt atctggtttt aagattttat gggtcactgg
    42061 atcaaaatga gccttgccat ctggaaaaat tttccccata ttggcctgat ggacaatatc
    42121 aaaaatacgt tctgggtcca cccccatcaa gacaaaactg ccgtaggtga agtaaagcgt
    42181 gtcaatcaag gcatccactt gccctatcaa atcttgctga gcaggtgtct tcttggctac
    42241 tttatctgct gccttatcaa gggcctgatg aagttgcgat acagcttgac caaaatcttc
    42301 ttcagaagga ctggctgctc gaacaaactc caccaattct tctattttaa aaccagccct
    42361 atgggttgca ccctctaaat cccaagctcg aggttcttct tgggttcgtt catccatcat
    42421 gtggtggaag gtcttgacct tattgaaatg atagtcacgg ctgacaaaga ctttttctga
    42481 agacaaaaca ccaaaatgtt ccaaggcctt gtggatccca tcttgttgat tgctagtggt
    42541 aatgtgcttg gcagcttcct tgacactgct actaccattt cccatagcga ccgacatacc
    42601 gacgccagcc agcatttcaa ggtcattatc tgagtcacca aaagccatga cttgattgag
    42661 gtcaaagcca tattctttcc caactcggcg aatgccttct aatttagaat ttccctgatt
    42721 gatgacatcc gatgcaaaag gattgctacg tgtcaatttc aagtcttcaa aatcagctgc
    42781 cgccttctca gattcttctg gtgtcatcag catcaaaact tggtagatag gctgattcat
    42841 caggtgaagc aggtcctctt ccttttgggg aacaaccttg ctgaccatgc gattaaaaga
    42901 ctgactcacc gtccgagtta aaacagaggg aacgaagcga ctaattcgtt gggaaaaaga
    42961 acccagacca aaggacatga ttttagaacc caacatggca tccttggtcc ctagggcaat
    43021 ctccgtgccc tcttttttag catagctaat tagatggcgc aaatgtaact tggaaatagg
    43081 gctcgtgaac aagactctgt ctttactaaa gatatactgg ccattatagg ttaccgcaaa
    43141 atccagatcc aaatcgtcca tcaattcctt aacaaaaaaa ggtcctcgcc ctgtcgctac
    43201 gccaactagt accccttgtt ctttgacaat cttaatcgca tccttagtgg atttcaaaac
    43261 actcttgcga ttgttgacca aggttccatc gatatcaaaa aaaacagctt tgacttccat
    43321 cctatcccaa tctccccttt tgtgatacaa tgattatacc acatttcaga aagagttagt
    43381 aaatcatgcc taagaaaatc cttgttttac atacgggtgg aactatttcc atgcaggccg
    43441 atgcttctgg cgctgttgtg acgagttcag ataatcccat gaaccatgtg tccaacccac
    43501 ttgaaggaat ccaagtccac gccttggact tttttaacct tccaagtccc catatcaaac
    43561 ccaaacatat gctggtcctc taccagaaaa ttaaagagga agcagataac tacgatggag
    43621 tggtgatcac acacggaacc gatactttag aggaaacagc ctatttcctt gataccatgg
    43681 aagttcccca tatgcctatc gttctaacag gagccatgcg tagctccaat gagctcggta
    43741 gtgatggtgt ttataattac ctaagtgctt tacgagtggc cagtgatgac agggctgctg
    43801 acaaaggagt tttggtcgtt atgaacgatg aaatccacgc tgccaagtat gtcaccaaaa
    43861 cacatacgac taatgtcaac accttccaga ctccaacaca tggccccctc ggtctcatca
    43921 tgaaacagga aatcctctac ttcaaaacag ctgaacctcg tgttcgcttt gaccttgatc
    43981 acatacaagg tttagtccct atcatctcgg cttatgctgg tatgacagat gagctgattg
    44041 atatgctgga tttagaacac ttggacggtt tgattatcca agccttcgga gctggtaata
    44101 ttcccaaaga aacggctcaa aaattagaaa gccttctgca aaaaggaatc ccagtctctc
    44161 tggtatcacg atgctttaac ggtattgccg agcctgttta tgcctaccag ggtgggggcg
    44221 tacagttgca aaaagcaggc gttttctttg ttaaagaact caacgcccaa aaagcccgct
    44281 tgaaactcct catcgccctc aatgccggac taacaggaca ggctttgaaa gactatatgg
    44341 aaggctaata ctcttcgaaa atctctgcaa accacgtcac gtcgccttac cgtatgtatg
    44401 gttactgact tcgtcagttc tatctacaac ctcaaaacag tgtgttgcgc agcctttaac
    44461 cagccgccta gtccgctcta tggtattcat taagtcaaca tctcttgttt aagagcacaa
    44521 aatcaggaaa tcttctcgat tccctgattt tttctattta cgttttcgtg ttgagctacg
    44581 ttctgtcaaa ccatgaggta agagaacttc acgttcttcc aactcttcct tatgcataat
    44641 cttggtcaac atacgcatac taatggcacc aaggtcataa agaggttggg caatcgttgt
    44701 caagtttgga cgggtaaagc gtgagatttg tgaatcatca ctagtaataa tttcaaaatc
    44761 ttctggcaca gaaacaccct tatcagccaa accgttcaag actcctgctg ccaactcatc
    44821 acctgtcaca actgctgcag ttgcatttga tgaaatcaaa cgctctgcta aggcgtaacc
    44881 atcatcatag ctatatttag attcaaatac caaaccctca ctataagcga ttcctgcttt
    44941 tttcaaggtt tccttgtagc caactaaacg aaccttacca ttgatgtcat ccactagcgg
    45001 accgctaacg aaagcaatac gctcattttc tttagcaagg taactcactg catcaattgt
    45061 tgcttgctta tagtcaatat tgacacttgg caactggtgc tcaacatcga cagttcctgc
    45121 gagaacaatc ggagtacgtg aacgcgaaaa ttctgagcga attttatctg tcaagtgata
    45181 acccatatag ataatgccat ctacctgctt tgaaaagagg gtattgacaa cagaaacttc
    45241 tttctcgtta tcttcatcgc tattagctag gacaatattg tacttgtaca tttctgcaat
    45301 atcatcaatc cccttagcca aactcgaaaa ataaccattg gtaatatttg gaatcacgac
    45361 accgacagtg gttgtctttt tacttgcaag accacgcgca actgcatttg gacgataatc
    45421 caagcgatca attacctcta gcactttttt acgggtattc tcttttacat ttttattgcc
    45481 attgaccaca cggctgaccg tcgccatgga aacacctgct tcacgagcga catcataaat
    45541 ggttactgta tcatctgcat tcattccttt tcctgtcctt tctatctcac acattctttt
    45601 acaagtagag gtactgattg aagctctata tctacttaca aaagtgaaga tgtgaaaatt
    45661 tcgttttcat atttctactt attccattct atcactaatt gtaaacactt tcaagtgttt
    45721 tttgaagatt gattgaaaaa atttcataga aaacctaggt ttagctcctt gctaccacct
    45781 tagactaaac aaaaaggagg aaactaagcc ctcctaaagt tatagtaaaa tgaaataaga
    45841 acaggataaa tcgatcagga cagtcaaatc gatttctaac aatgttttag aagtagaggt
    45901 gtactattct agtttcaatc tactataggt attgttccat tcactaccgt caattttagc
    45961 acatagtctt catgaaaata ttatatcatc ataaccaacc agattctttt gcgatattag
    46021 ctgcctctgt tcgattacca gcatccaatt ttgaaagaat attggtgaca tagtttcgaa
    46081 tagttccgtt tgagaggtaa agctgatctg cgatttcttg gttggataag ccccgggcga
    46141 tcccctttaa gacagcaatc tcttgttctg tcaacggatt gggacgggtc atcaccactt
    46201 ccatcaattc aggcgaatac tccttgcgtc cttcgaggac ggtgtgcaag gtttgcatga
    46261 ggtctgcaac gcttcgttcc tttaatacat aagcatccac tccagccttg accgcacgtt
    46321 caaaataccc agcacgcttg aaggtcgtca ccacaaccac ctttgtttca agcctttctg
    46381 atcgtatcca ctccaagact tcaagacctg tcttaacagg catttctacg tcaaggatgg
    46441 cgatatctac agactccttt tctaatagtt ggattgcttc ttgcccattc ttggcttgaa
    46501 ggacagactc cacatctggt tgaagcgtga gcaattgaca catggcatct cgcaacatac
    46561 tttgatcttc tgcgactaat actttcatct tagtttctct ccttataagg tagtcgaact
    46621 tgcacttccg ttggatgttt ctgactgatt acacttactt ctcctgaaaa tggaaaaaca
    46681 cgatctcgga ttgtatggag ctcatctcct tttagaaaag caaagccgca gccatcatca
    46741 cttactgtta aaatgagttc cttctctgtc cgttctaatt ttaagtaagc tttagacgct
    46801 ttggcatgtt tgatgatatt ggtcaccaac tcaagcaaaa tcatagaagc cattgactcc
    46861 aattcttgag taaggctagc agtatctagt tggttatccg tttccacctc aattccagca
    46921 atttctaaca tctttttcac agtctctagt tcggatgtca aagttctaga cttaagattt
    46981 tccacaatgg ttcgaacttc acgcattgat tctttgctaa tttgctgtat ttctcttaat
    47041 tccttttcca cttgtggata agcctgcatt tgaaatagct gcaaggctag atctgtcttg
    47101 acactaagca tagcaaaggt atgtcccaga ctatcatgca aatcctgacc gatacgattg
    47161 cgctcatttt ctgctagcaa tagatttatc tgggtatttt gcttgacctg agcttctttc
    47221 aaatcctcga caaggcgaat tcgaaccgag cccaaagtca tcaaatcgac aaaagtaaga
    47281 attacaagca tatagactag aaactcaact tcgattctct gaaaaatcaa aagtcgcccc
    47341 acaacaagga cttgagcaag gagaaatgtc catacatgta aagactttaa actacgtacg
    47401 ccaaaatgat aaattaagag attggaaagg aaaaagaaaa accagatata attcccagca
    47461 acaaaggcgg tattcccagc tacatagacc agcatgatcc cccagaaaag ccatgatatg
    47521 cgctggttct tagttattaa aacacccaaa tacgtcacta caaatagaat atcaaccaat
    47581 aaatgccaag caggaagctc cccagtcact acaggtagga tggggaaaat cataaaaatt
    47641 aaacttgccc aaaacatata gtgtatgctt ttcagtcttt caagcattaa gcattctcct
    47701 tatgaccttg aaggtaaatg gtcaaaccaa acaaaactgc tgaaaaaaca agtagataaa
    47761 ctgtggctga tagattgatg ccaccctcgt ttaagaaggt cttgagcaac tccatcaatt
    47821 gataggtcgg gagacactta ccaactgctt gcatccagtc tggaaataaa gaaatgggca
    47881 tccagagtcc gcctaaaaca gccaatccta gataaagaag attgcccaca acagacatca
    47941 gctgactagt tggtaagaga gtcaaggtca agccaagtgc tacaaaagca atactcccca
    48001 caatcagcaa aatcgcagct ccaacccatt ttactagagg catgtctaca cctcttacaa
    48061 aatgtccaac tgtaaaaaca accagaattg agaccaaata atcaaccagc atacttgtta
    48121 tctttgatag ataatattct accatattta cagggctatg acgcaatgtt ttctgccagt
    48181 tgttcatctt atcggtatgt aaaacagctg gaaatgagag gatagttgtc gacatcatgg
    48241 aaaaggcagt catggagatg aggtaatcac gcataaaatt cgcgagttca cctggtgtgt
    48301 cctgatagat accagaaaaa aataaataga aagccgtcgg catccctacc gacaatagat
    48361 aatagattaa ttgtcgtttg gtcaataaaa attctatctt actaagtgct atccatcgtt
    48421 tcatcttagt tatctccctt ctgcgtctct tcaaagattg tattcaacaa actacgatta
    48481 ttaacttcga tttcttgcat cctacatcct gcttgggcta atagttccca gaaagcatct
    48541 gcttctcgag tgactacttg taaagaatct tgctttaggg tccagttttc aaccaaattt
    48601 gactgctcta cgacttcctt gtaagctata ggaaggataa agtgcttttc tatttcctcg
    48661 ctacgcatag ctagaggcgt cgtatctcga atcaactctc ccttatttaa gagcaaaatg
    48721 cggtctgcag tgtgttccac ttcctcaata taatgggacg aatagagaat ggtgactcct
    48781 tgcgctttta actcctggac aatttcccaa aaacgttgac gagttgaggt atccatggac
    48841 gcagtaggct catctaaaaa aacaatcttt ggtcgcccaa ttaaggtcaa gacgaaagaa
    48901 aagagacgct tttgaccgcc tgataatttt tctgccaact gttctttttg ttgcttgaca
    48961 aactgcaata gttgatcaat ttcctgattg ctcaaaggat ttggatagat acgttgaaag
    49021 aaagcaatca actctttaac ttttaatttc tgaacgatta cattttcttg agggaggtaa
    49081 gccctagtat agtctaactt agaactcgtc actggtaaac cttgaataga tacttgaccg
    49141 cttgtgacca gtttatctcc aagcaaacaa tctaagagtg ttgtctttcc ggcaccattt
    49201 ggaccaatta aggcaacaca ttcaccatcg ttgatttcaa aggagatatt ccgcaaaatt
    49261 tccttgtctt ttattttctt actcaatttc tcaactttaa ccaccgtcat gagactctcc
    49321 tttcaaccac tccattccca taaggaaaac gacgaaaatc ataaatccaa accccaaagc
    49381 accacgaatg aattggcgaa gcaaggcttg atcaaaccaa tcagtaaaca tttccactaa
    49441 ccataccaag agtgacaggc cgataaagaa atagatgatc cctctcttca ttcctcaaac
    49501 tcctttttca catctctgac taatttcaaa ccttctctaa caagccaaga catgattcca
    49561 aagccagcaa agaccttcca aggaaaatgg tagaaatcct catccaatcc cgaaaacatg
    49621 agataggtca taactcctgc tactactaaa cttactgcga taatcatttt atttctcatc
    49681 tcttcttccc ccatttcata ctacaattat agtcttttaa aatcagagga gacagaagct
    49741 tctgtcacta aaaaatatga caaatgtcat aaaaaattct gttcaaaaca agcaagatac
    49801 actatacaat aaaacacaat cagaaaaatc taaggcaact tcctcaaaag agatatcaaa
    49861 cccaattcac accataatgt aaactaatac ttatttaaaa tcaaaaagag taaaaatttt
    49921 tatcagacaa acacatatat agtgtattga atctataaca gtaggcctta aatactaaaa
    49981 tatttctata aattaattta actttcctga tagaactgtt catatcttat ttcaattctc
    50041 tatattatac gttgaaccaa acccttctat tgctttctta aaaatttata agagttataa
    50101 aatctgttaa atttcaatgt gtatatctaa actacggtat ttattgaaaa gactggagac
    50161 aaaaagtata cgctgccaaa atgaattact gaaaatcaaa aaagagagaa ccaaactgat
    50221 tccctcttaa tgtatataat atctagtttt aaaaatacac actcacatat ctctgt
//
LOCUS       DAVLXH010000010        46546 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00028199
            SAMN33607166-rid17955573.denovo.010, whole genome shotgun sequence.
ACCESSION   DAVLXH010000010 DAVLXH010000000
VERSION     DAVLXH010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607166
            Sequence Read Archive: SRR23725544
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 46546)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 46546)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721421.1
            Genome Coverage       :: 115x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:42:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,210
            CDSs (total)                      :: 2,161
            Genes (coding)                    :: 2,023
            CDSs (with protein)               :: 2,023
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 73 of 138
            Pseudo Genes (incomplete)         :: 60 of 138
            Pseudo Genes (internal stop)      :: 40 of 138
            Pseudo Genes (multiple problems)  :: 31 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..46546
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607166-rid17955573.denovo.010"
                     /strain="AUSMDU00028199"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1349"
     gene            150..1379
                     /gene="arcA"
                     /locus_tag="VYO11_000646"
     CDS             150..1379
                     /gene="arcA"
                     /locus_tag="VYO11_000646"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000094613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HEV1595246.1"
                     /translation="MSSHPIQVFSEIGKLKKVMLHRPGKELENLLPDYLERLLFDDIP
                     FLEDAQKEHDAFAQALRDEGIEVLYLEQLAAESLTSPEIRDQFIEEYLDEANIRDRQT
                     KVAIRELLHGIKDNQELVEKTMAGIQKVELPEIPDEAKDLTDLVESEYPFAIDPMPNL
                     YFTRDPFATIGNAVSLNHMFADTRNRETLYGKYIFKYHPIYGGKVDLVYNREEDTRIE
                     GGDELVLSKDVLAVGISQRTDAASIEKLLVNIFKKNVGFKKVLAFEFANNRKFMHLDT
                     VFTMVDYDKFTIHPEIEGDLHVYSVTYENEKLKIVEEKGDLAELLAQNLGVEKVHLIR
                     CGGGNIVAAAREQWNDGSNTLTIAPGVVVVYDRNTVTNKILEEYGLRLIKIRGSELVR
                     GRGGPRCMSMPFEREEV"
     gene            1440..2453
                     /gene="argF"
                     /locus_tag="VYO11_000647"
     CDS             1440..2453
                     /gene="argF"
                     /locus_tag="VYO11_000647"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000195397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HEV1595247.1"
                     /translation="MNSVFQGRSFLAEKDFTRAELEYLIGLSAHLKDLKKRNIQHHYL
                     AGKNIALLFEKTSTRTRAAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRMF
                     DGIEFRGFSQRMVEELAEFSGVPVWNGLTDEWHPTQMLADYLTVQENFGRLEGLTLVY
                     CGDGRNNVANSLLVTGAILGVNVHIFSPKELFPEKEIVELAEGFAKESGAHVLITEDA
                     DEAVKDADVLYTDVWVSMGEEDKFAERVALLKPYQVNMDLVKKAGNENLIFLHCLPAF
                     HDTHTVYGKDVAEKFGVEEMEVTDEVFRSKYARHFDQAENRMHTIKAVMAATLGNLYI
                     PKV"
     gene            2618..3565
                     /gene="arcC"
                     /locus_tag="VYO11_000648"
     CDS             2618..3565
                     /gene="arcC"
                     /locus_tag="VYO11_000648"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003025409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HEV1595248.1"
                     /translation="MANRKIVVALGGNAILSSDPSAKAQQEALVETAKHLVKLIKNGD
                     DLIITHGNGPQVGNLLLQHLASDSEKNPAFPLDSLVAMTEGSIGFWLKNALQNALLDE
                     GIEKNVASVVTQVVVDKNDPAFVNLSKPIGPFYSEEEAKAEAEKSGATFKEDAGRGWR
                     KVVASPKPVDIKEIETIRTLLNNGQVVVAAGGGGIPVVKENNGHLTGVEAVIDKDFAS
                     QRLAELVDADLFIILTGVDYVFVNYNKPNQEKLEHVNVAQLEEYIKQDQFAPGSMLPK
                     VEAAIAFVNGRPEGKAVITSLENLGALIESESGTIIEKG"
     gene            3776..5287
                     /locus_tag="VYO11_000649"
     CDS             3776..5287
                     /locus_tag="VYO11_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004191872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HEV1595249.1"
                     /translation="MSEKAKKGFKMPSSYTVLLIIIAIMAVLTWFIPAGAFIEGIYEA
                     HPQNPQGIWDVLMAPIRAMLGTHPEEGSLIKETSAAIDVAFFILMVGGFLGIVNKTGA
                     LDVGIASIVKKYKGREKMLILVLMPLFALGGTTYGMGEETMAFYPLLVPVMMAVGFDS
                     LTGVAIILLGSQIGCLASTLNPFATGIASATAGVGTGDGIVLRLIFWVTLTALSTWFV
                     YRYADKIQKDPTKSLVYSTRKEDLKHFNVEESSSVESTLSSKQKSVLFLFVLTFILMV
                     LSFIPWTDLGVTIFDDFNAWLTGLPVIGNIVGSSTSALGTWYFPEGAMLFAFMGILIG
                     VIYGLKEDKIISSFMNGAADLLSVALIVAIARGIQVIMNDGMITDTILNWGKEGLSGL
                     SSQVFIVVTYIFYLPMSFLIPSSSGLASATMGIMAPLGEFVNVRPSLIITAYQSASGV
                     LNLIAPTSGIVMGALALGRINIGTWWKFMGKLVVAIIVVTIALLLLGTFLPFL"
     gene            5309..6640
                     /locus_tag="VYO11_000650"
     CDS             5309..6640
                     /locus_tag="VYO11_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000686986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase"
                     /protein_id="HEV1595250.1"
                     /translation="MKIDITNQVKDEFLISLKTLISYPSVLNEGENGTPFGQAIQDVL
                     EKTLEICQDIGFTTYLDPKGYYGYAEIGQGAELLAILCHLDVVPSGDEADWQTPPFEA
                     TIKDGWVFGRGVQDDKGPSLAALYAVKSLLDQGIQFKKRVRFIFGTDEETLWRCMARY
                     NTIEEQASMGFAPDSSFPLTYAEKGLLQVKLHGPGSDQLELEVGGAFNVVPDKANYQG
                     PLYEQVCNDLKEAGYDYQSTEQTVTVLGVPKHAKDASQGINAVIRLATILAPLQEHPA
                     LSFLATQAGQDGTGRQIFGDIADEPSGHLSFNVAGLMINHERSEIRIDIRTPVLADKE
                     ELVELLTRCAQNYQLRYEEFDYLAPLYVAKDSKLVSTLMQIYQEKTGDNSPAISSGGA
                     TFARTMPNCVAFGALFPGAKQTEHQANECAVLEDLYRAMDIYAEAVYRLAT"
     gene            complement(7046..7336)
                     /locus_tag="VYO11_000651"
     CDS             complement(7046..7336)
                     /locus_tag="VYO11_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000501069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1595251.1"
                     /translation="MGALGYYEGFVPYVSNQYKNQAEEEGKPLSDKYIFEKILGKTYA
                     AFKKDQINERVEKLGKLKPITINYNGKSEVIDSKEKLQELMNKAVKDEVAQI"
     gene            complement(7324..7576)
                     /locus_tag="VYO11_000652"
                     /pseudo
     CDS             complement(7324..7576)
                     /locus_tag="VYO11_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657761.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif.; frameshifted; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
     gene            7780..7857
                     /locus_tag="VYO11_000653"
                     /pseudo
     CDS             7780..7857
                     /locus_tag="VYO11_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(7975..8859)
                     /locus_tag="VYO11_000654"
     CDS             complement(7975..8859)
                     /locus_tag="VYO11_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001838996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HEV1595252.1"
                     /translation="MIFLIVCVLLLVIVTLSTVYVVRQQSVAIIERFGKYQKVANSGI
                     HIRLPFGIDSIAARIQLRLLQSDIVVETKTKDNVFVMMNVATQYRVNEQSVTDAYYKL
                     IRPESQIKSYIEDALRSSVPKLTLDELFEKKDEIALEVQHQVAEEMTTYGYIIVKTLI
                     TKVEPDAEVKQSMNEINAAQRKRVAAQELAEADKIKIVTAAEAEAEKDRLHGVGIAQQ
                     RKAIVDGLAESITELKEANVGMTEEQIMSILLTNQYLDTLNTFASKGNQTIFLPNTPN
                     GVDDIRTQILSALRAEKK"
     gene            complement(9003..10154)
                     /locus_tag="VYO11_000655"
     CDS             complement(9003..10154)
                     /locus_tag="VYO11_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HEV1595253.1"
                     /translation="MATFYVPAVNLIGKGVVNEVGPYIKELGYKKALLVTDKYIEGSD
                     ILPKVLKPLDTEGIEYVIFSDVEPNPTCKNVTDGVAALQEHGCDFIISLGGGSPQDAA
                     SCISIMVTNGGKPQDYEGLHKSAKKGLPVVAINTTAGTSAEITINYVITDEERKVKMV
                     MVDKNSLALISVNDPELMLSKPQALTAATGMDALTHAVEALVTPGAYDVTKKLSIGAI
                     ELIKEYLPRAVANGHDIEAREGMVNAIFLGGMSFNNAGLGYVHSMAHQLGAVYNLPHG
                     VCCAMLLPVIERENAKRVPEAFRNVAKALGLHVEGKSDQECADYAIAEIEKLSETVGI
                     PKKLTELGIEEKDFDFEYLSKNALIDACAPGNPFMPTLEETIAFYKELF"
     gene            complement(10300..12066)
                     /locus_tag="VYO11_000656"
     CDS             complement(10300..12066)
                     /locus_tag="VYO11_000656"
                     /EC_number="5.3.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fucose isomerase"
                     /protein_id="HEV1595254.1"
                     /translation="MIQHPRIGIRPTIDGRRQGVRESLEVQTMNMAKSVADLISSTLK
                     YPDGEPVECVISPSTIGRVPEAAASHELFKKSNVCATITVTPCWCYGSETMDMSPDIP
                     HAIWGFNGTERPGAVYLAAVLASHAQKGIPAFGIYGRDVQEASDTAIPEDVKEKLLRY
                     ARAALATGLMRDTAYLSMGSVSMGIGGSIVNPDFFQEYLGMRNESVDMTEFTRRMDRG
                     IYDPEEFERAMVWVKEHIKEGVDRNREDLILSKEEKEKQWEFVIKMFMIGRDLMVGNP
                     RLAELGFEEEAVGHHALVAGFQGQRQWTDHFPNGDFMETFLNTQFDWNGIRKPFVFAT
                     ENDSLNGVSMLFNYLLTNTPQIFADVRTYWSPEAVKRVTGHTLEGRAAAGFLHLINSG
                     SCTLDGTGQATRDGKPVMKPFWELEESEVQAMLENTDFPPANREYFRGGGFSTRFLTK
                     GDMPVTMVRLNLLKGVGPVLQIAEGYTLELPEDVHHTLDNRTDPGWPTTWFAPRLTGK
                     GAFKSVYDVMNNWGANHGAITYGHIGADLITLASMLRIPVNMHNVPEEDIFRPKNWSL
                     FGTEDLESADYRACQLLGPLHK"
     gene            complement(12123..15239)
                     /locus_tag="VYO11_000657"
     CDS             complement(12123..15239)
                     /locus_tag="VYO11_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001031112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="discoidin domain-containing protein"
                     /protein_id="HEV1595255.1"
                     /translation="MNKEKIKRKLITILFVCIGMLCFGLLAGVKADNRVQMRTTINNE
                     SPLLLSPLYGNDNGNGLWWGNTLKGAWEAIPEDVKPYAAIELHPAKVCKPTSCIPRDT
                     KELREWYVKMLEEAQSLNIPVFLVIMSAGERNTVPPEWLDEQFQKYSVLKGVLNIENY
                     WIYNNQLAPHSAKYLEVCAKYGAHFIWHDHEKWFWETIMNDPTFFEASQKYHKNLVLA
                     TKNTPIRDDAGTDSIVSGFWLSGLCDNWGSSTDTWKWWEKHYTNTFETGRARDMRSYA
                     SEPESMIAMEMMNVYTGGGTVYNFECAAYTFMTNDVPTPAFTKGIIPFFRHAIQNPAP
                     SKEEVVNRTKAVFWNGEGRISSLNGFYQGLYSNDETMPLYNNGRYHILPVIHEKIDKE
                     KISSIFPNAKILTKNSEELSSKVNYLNSLYPKLYEGDGYAQRVGNSWYIYNSNANINK
                     NQQVMLPMYTNNTKSLSLDLTPHTYAVVKENPNNLHILLNNYRTDKTAMWALSGNFDA
                     SKSWKKEELELANWISKNYSINPVDNDFRTTTLTLKGHTGHKPQINISGDKNHYTYTE
                     NWDENTHVYTITVNHNGMVEMSINTEGTGPVPFPTPDKFNDGNLNIAYAKPTTQSSVD
                     YNGDPNRAVDGNRNGNFNSGSVTHTRADNPSWWEVDLKKMDKVGLVKIYNRTDAETQR
                     LSNFDVILYDNNRNEVAKKHVNNLSGESVSLDFKEKGARYIKVKLLTSGVPLSLAEVE
                     VFRESDGKQSEEDIDKITEDKVVSTNKVATQSSTNYEGVAALAVDGNKDGDYGHHSVT
                     HTKADSNAWWQVDLGEEFTVSKVDIYNRTDAEPQRLSNFDVIFLSSSGEEVFRRHFDK
                     VVDGLLSLKVPSVGAKLVKIELKSAAIPLSLAEVEVYGSKRTPKKLSNIALTKETRQS
                     STDYNGFSRLAVDGNKNGDYGHHSVTHTKGDSPSWWEIDLAQTEELEKLIIYNRTDAE
                     IQRLSNFDIIIYDSNNHEVFKQHIDSLESNNLSIDLKGLKGKKVRISLRNAGIPLSLA
                     EVEVYTYK"
     gene            complement(15249..17543)
                     /locus_tag="VYO11_000658"
     CDS             complement(15249..17543)
                     /locus_tag="VYO11_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
                     /protein_id="HEV1595256.1"
                     /translation="MKLWYKKAASNWNEALPIGNGHLGGMIYGSATKECIQLNDETIW
                     YRGKSDRNNPDSLLHLKKIREYLLDGEIQKAEELIKLTMFATPRDQSHYELLGELYIE
                     HIDIQSCALSLYERELDLDTAISNVVFEPNSCNLQIKREYFTSFNKNILCCRIVSSVQ
                     NTLNLNINLGRNKRFNDEVSKLDSSTILMSASAGGRKGVQFKVVCHSKVTDGEVSVLG
                     ETIVIRNATEVFLYLKSMTDYWGNIDISSLQGEFSSIDYFTEKDEHVKKYQEQFNRVD
                     FKLDYSKDCLSIPTNLLLENTKKYSNYLTNLLFHYGRYLLISSSQPNGLPVNLQGIWC
                     DELNPIWGSKYTININTQMNYWMVGPCDLPEVEYPLFDMLERMREPGRLTAKKMYGAR
                     GFTAHHNTDGFGDTAPQSHAMGAAIWVLTIPWLCTHIWEHYLYFQDERILTEHFEMIK
                     EAFLFFEDYLFEVDGYLMTGPSVSPENKYRLKNGIEGNACLSSTIDNQILRYFCDSCI
                     GIAKQLGDNSDFISRVKELKKKLPKTKIGSNGQIQEWLEDYEEVEPGHRHISPLFGLY
                     PYNEIDIHKTPELAEAAKITINRRLSNANFLSSQEREQAINNWLVSGLHASTQTGWSA
                     AWLIHFFARLYQGEPAYNQINGLLNNATLGNLFLDHPPFQIDGNLGLVSGICELLVQS
                     HHNWLSLIPALPSAWSEGEVKGFRVRGGYKVSFAWKNGDITFLKLEGGNKDQKVRVRI
                     YGKNTDVQNIELVFNSEKIIELNF"
     gene            complement(17602..18402)
                     /locus_tag="VYO11_000659"
     CDS             complement(17602..18402)
                     /locus_tag="VYO11_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEV1595257.1"
                     /translation="MMNNKVTKVELKKVFKRSFMYGSSWNYERMQNLGFLYTILPVLK
                     KLYPDKDSASPAMKRHLEFFNTHQTAAPFILGVTSAMEEQEGNEGAASITGIKVGLMG
                     PLAGLGDSLFWLTLVPICFSIGASYSKDGGALGIFIALILFNIINIPVKYFGLKYGYT
                     KGSSLIQENNTKGTLNRVTSMATALGLVLVGGLIPSMVGINFGLEFKQGELVISVQEM
                     ITKLIPGFIPMALTLLMCKLIRKGKNPVVLIFSVMAIGVILVVLGILK"
     gene            complement(18399..19172)
                     /locus_tag="VYO11_000660"
     CDS             complement(18399..19172)
                     /locus_tag="VYO11_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000899624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEV1595258.1"
                     /translation="MLFTQALLVTLVGIIATIDYNGPLFMIHRPLVTSAMVGLVLGDF
                     TQGVLIGSALELTWLGVTGIGGYTPPDTISGAIIGTAFGILSGQGETAGIAIAVPIAV
                     ATQQLDVLAKTLDVYFVKKADNDAKNGDYSKIGFYHYSSLVLITLFKIVPIFLAIMLG
                     GEYVADLFAKVPPIVMQGLNSAGALLPSIGFGMLLNMMLKKNMWVFLLIGFICSVYGG
                     MSTIGISLVGIAVAYFYDMIGSKPQETTSSSDVEEDLDL"
     gene            complement(19197..19667)
                     /locus_tag="VYO11_000661"
     CDS             complement(19197..19667)
                     /locus_tag="VYO11_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000020992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV1595259.1"
                     /translation="MSIEFVRIDDRLVHGQVVTTWLKKYDIEQVIIVNDRISEDKTRQ
                     SILKISAPVGLKIVFFSVKRFVEVLNSVPIKKRTMLIYTNPKDVYDSIEGNLKLEYLN
                     VGQMSKTEENEKVTGGVALGEEDKYYFKKIVDKGTRVEIQMVPNDKVTMLEKFL"
     gene            complement(19658..20089)
                     /locus_tag="VYO11_000662"
     CDS             complement(19658..20089)
                     /locus_tag="VYO11_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000483177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV1595260.1"
                     /translation="MFNRGILVASHGDFASGALMTAEMFVGETTNDRVRTLGLMPGEN
                     IVEFEHYFKNQVDELLDSNQEVIVLTDLIGGSPNNVALSRFLNLDSVDIVTGFNIPLL
                     VELISNYDSKINLEEIVHNAQNSLFNVKQQLNVEEEEDLCL"
     gene            complement(20082..20522)
                     /locus_tag="VYO11_000663"
     CDS             complement(20082..20522)
                     /locus_tag="VYO11_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000912112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RbsD/FucU family protein"
                     /protein_id="HEV1595261.1"
                     /translation="MLKHIPKNISPDLLKTLMEMGHGDEIVLADANYPSASCANKLIR
                     CDGVNIPELLDSILYLMPLDSYVDSSIQFMNVVSGDDIPKIWGTYRQMIEGHGTDLKT
                     ITYLRREDFYERSKKAYAIVATGETSLYANIILKKGVVVERENV"
     gene            complement(20534..21172)
                     /locus_tag="VYO11_000664"
     CDS             complement(20534..21172)
                     /locus_tag="VYO11_000664"
                     /EC_number="4.1.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001286141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fuculose-phosphate aldolase"
                     /protein_id="HEV1595262.1"
                     /translation="MSDVKQELIKYGKKLVETDLTKGTGGNLSVFDREKQLMAITPSG
                     IDFFEIKESDIVVMDINGNVVEGERLPSSEWYMHLIQYQTRDDIDAIIHAHTTYATVL
                     ACLREPLPASHYMIAVAGKDVRVAEYATYGTKELAVNAAKAMEGRRAVLLANHGILAG
                     AQNLLNAFNIVEEVEYCAKIYCLAKNFGEPVVLPDEEMELMAEKFKTYGQRK"
     gene            complement(21287..22690)
                     /locus_tag="VYO11_000665"
     CDS             complement(21287..22690)
                     /locus_tag="VYO11_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulokinase"
                     /protein_id="HEV1595263.1"
                     /translation="MEAVLAIDLGATSGRAIVGYLSENKLVMEEINRFSNLPIRVKGH
                     LSWDVDFLLAKILESIRLANTSYKILSIGIDTWGVDFGLIDNEGKLLSQPVHYRDERT
                     KGVLKEISEMTELEKLYSETGNQIMEINTLFQLFKARQESPDSFYKTNKILLMPDLFN
                     YLLTGKFATEKSIASTTQLFDPRSQNWNQNILKLFELDSTLLPEIVSEGNVLGRIKKE
                     YGLSDIPVVNVCSHDTASAIVSVPKTEGSLFISSGTWSLVGVELTSPILTTESFSYGF
                     TNEVGKDGVITFLKNCTGLWIIEELRRSFERRGKAYSFDDIRTMVEKEKENLPLIDTE
                     STEFATESDMHKTLTEYLAYHHETREWTDGQLFKIVYESLAETYRKAIELLEELTHKV
                     YKRIYVIGGGARASYFNQMIADRTGKEVLTGLTEATAVGNIVVQLIAMGQLKGMEEAH
                     HVIEEFLQLESYYSQKN"
     gene            22866..23639
                     /locus_tag="VYO11_000666"
     CDS             22866..23639
                     /locus_tag="VYO11_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEV1595264.1"
                     /translation="MIKDERVLELIEIIKKKKRIAVKELAEITFSSTSTLRRDLIFLE
                     NQGLIKRKHGYVTLSSMNTIELSHQIREGESTRQKRLIASLAKDFIRSGMCIYLDSST
                     TVYELCPYLSELDNLIIFTNGLHTAQTLSETVKDSSKIFITSGEVKHQSCSVVNYDKE
                     NSLLDHFNIDLAFCSARGIDDQYVYEASLSQAISKKNIIDKAHETILLIDSSKFYKTG
                     FFKINPLSKYTTFISDTLPDQKLLDAVELFDGEWVSDIQ"
     gene            complement(24766..26271)
                     /gene="adcA"
                     /locus_tag="VYO11_000667"
     CDS             complement(24766..26271)
                     /gene="adcA"
                     /locus_tag="VYO11_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding
                     lipoprotein AdcA"
                     /protein_id="HEV1595265.1"
                     /translation="MKKISLLLASLCALFLVACSNQKQADGKLNIVTTFYPVYEFTKQ
                     VAGDTANVELLIGAGTEPHEYEPSAKAVAKIQDADTFVYENENMETWVPKLLDTLDKK
                     KVKTIKATGDMLLLPGGEEEEGDHDHGEEGHHHEFDPHVWLSPVRAIKLVEHIRDSLS
                     ADYPDKKETFEKNAAAYIEKLQALDKAYAEGLSQAKQKSFVTQHAAFNYLALDYGLKQ
                     VAISGLSPDAEPSAARLAELTEYVKKNKIAYIYFEENASQALANTLSKEAGVKTDVLN
                     PLESLTEEDTKAGENYISIMEKNLKALKQTTDQEGPAIEPEKAEDTKTVQNGYFEDAA
                     VKDRTLSDYAGNWQSVYPFLEDGTFDQVFDYKAKLTGKMTQAEYKAYYTKGYQTDVTK
                     INITDNTMEFVQGGQSKKYTYKYVGKKILTYKKGNRGVRFLFEATDADAGQFKYVQFS
                     DHNIAPVKAEHFHIFFGGTSQEALFEEMDNWPTYYPDNLSGQEIAQEMLAH"
     gene            complement(26281..27087)
                     /locus_tag="VYO11_000668"
     CDS             complement(26281..27087)
                     /locus_tag="VYO11_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEV1595266.1"
                     /translation="MLSLLSYDFIQRAFLAVIAMSLFSPVLGTFLILRRQSLMSDTLS
                     HVSLSGVAFGLVLGISPTVSTIAIVLIAAVFLEYLRTVYKSFMEIGTAILMSTGLAVS
                     LIVMSKGKSSSSMSLDQYLFGSIVTISEEQVISLFVIAAVVLILTFLFLRPMYILTFD
                     EDTAFVDGLPVRTMSILFNMVTGVAIALMIPAAGALLVSTIMVLPASIALRLGKNFKS
                     VMLLASAIGFLGMVAGLYISYYAETPASASITIIFVTVFILISLVRRFIK"
     gene            complement(27080..27784)
                     /locus_tag="VYO11_000669"
     CDS             complement(27080..27784)
                     /locus_tag="VYO11_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEV1595267.1"
                     /translation="MRYITVEDLSFYYDKEPVLEHINYSVDSGEFVTLTGENGAAKTT
                     LIKASLGILQPRIGKVAISKTNTQGKKLRIAYLPQQIASFNAGFPSTVYEFVKSGRYP
                     RKGWFRRLNAHDEEHIKASLDSVGMWEHRDKRLGSLSGGQKQRAVIARMFASDPDVFI
                     LDEPTTGMDAGSKNEFYELMHHSAHHHGKAVLMITHDPEEVKDYADRNIHLVRNQDSP
                     WRCFNVHENGQEVGHA"
     gene            complement(27784..28224)
                     /gene="adcR"
                     /locus_tag="VYO11_000670"
     CDS             complement(27784..28224)
                     /gene="adcR"
                     /locus_tag="VYO11_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent transcriptional regulator AdcR"
                     /protein_id="HEV1595268.1"
                     /translation="MRQLAKDINAFLNEVILQAENQHEILIGHCTSEVALTNTQEHIL
                     MLLSEESLTNSELARRLNVSQAAVTKAIKSLVKEGMLETSKDSKDARVIFYQLTDLAR
                     PIAEEHHHHHEHTLLTYEQVATQFTPNEQKVIQRFLTALVGEIK"
     gene            complement(28379..29647)
                     /gene="dltD"
                     /locus_tag="VYO11_000671"
     CDS             complement(28379..29647)
                     /gene="dltD"
                     /locus_tag="VYO11_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000919885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HEV1595269.1"
                     /translation="MLKRLWMIFGPVLIAGLLVFLLIFFYPTEMHHNLGAEKRSAVAT
                     TIDSFKERSQKVRALSDPNVRFVPFFGSSEWLRFDGAHPAVLAEKYNRSYRPYLLGQG
                     GAASLNQYFGMQQMLPQLENKQVVYVISPQWFSKNGYDPAAFQQYFNGDQLTSFLKHQ
                     SGDQASQYAATRLLQQFPNVAMKDLVQKLASKEELSTADNEMIELLARFNERQASFFG
                     QFSVRGYVNYDKHVAKYLKILPDQFSYQAIEDVVKADAEKNTSNNEMGMENYFYNEQI
                     KKDLKKLKDSQKSFTYLKSPEYNDLQLVLTQFSKSKVNPIFIIPPVNKKWMDYAGLRE
                     DMYQQTVQKIRYQLESQGFTNIADFSKDGGEPFFMKDTIHLGWLGWLAFDKAVDPFLS
                     NPTPAPTYHLNERFFSKDWATYDGDVKEFQ"
     gene            complement(29640..29879)
                     /gene="dltC"
                     /locus_tag="VYO11_000672"
     CDS             complement(29640..29879)
                     /gene="dltC"
                     /locus_tag="VYO11_000672"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005591431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HEV1595270.1"
                     /translation="MDIKSEVIEIIDELFMEDVSDMMDEDLFDAGVLDSMGTVELIVE
                     IENRFDIRVPVTEFGRDDWNTANKIIAGIVELQNA"
     gene            complement(29893..31137)
                     /gene="dltB"
                     /locus_tag="VYO11_000673"
     CDS             complement(29893..31137)
                     /gene="dltB"
                     /locus_tag="VYO11_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HEV1595271.1"
                     /translation="MMEFFQQLPHLEPYGNPQYFVYVIAATLPIFIGLFFKKRFAWYE
                     VLVSLFFIVTMLVGGKTNQLAALGIYLCWEILLLLFYKHYRKSKDGKWVFYLVSFLSL
                     LPIIFVKVQPAINGTQSLLGFLGISYLTFRSVGIIIELRDGVIKDFTLWEFLRFLLFM
                     PTFSSGPIDRFKRFNENYQAIPERDELMDMLDESVRYIMWGFLYKFILAHVLGETLLP
                     PLKNLALQSGGFFNLYALAVMYTFGLELFFDFAGYSMFALAISNLMGIRSPINFNKPF
                     LSRDLKEFWNRWHMSLSFWFRDFVFMRMVMVLTRKKVFKNRNVTSSMAYIVNMLIMGF
                     WHGVTWYYIAYGLFHGLGLVINDAWVRKKKTLNKERKKAGKAALPENRWIQLLGMVVT
                     FHVVMLSFLIFSGFLNNLWFKK"
     gene            complement(31134..32684)
                     /gene="dltA"
                     /locus_tag="VYO11_000674"
     CDS             complement(31134..32684)
                     /gene="dltA"
                     /locus_tag="VYO11_000674"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012972622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HEV1595272.1"
                     /translation="MSNKPIADMIETIEHFAQTQPSYPVYNVLGQEHTYGDLKADSDS
                     LAAVIDQLGLPEKSPVVVFGGQEYEMLATFVALTKSGHAYIPIDSHSALERVSAILEV
                     AEPSLIIAISAFPLEQVSTPMINLAQVQEAFAQGNNYEITHPVKGDDNYYIIFTSGTT
                     GKPKGVQISHDNLLSFTNWMITDKEFATPSRPQMLAQPPYSFDLSVMYWAPTLALGGT
                     LFTLPSVITQDFKQLFAAIFSLPIAIWTSTPSFADMAMLSEYFNSEKMSGITHFYFDG
                     EELTVKTAQKLRERFPNARIINAYGPTEATVALSAVAVTDEMLATLKRLPIGYTKADS
                     PTFIIDEEGNKLPNGEQGEIIVSGPAVSKGYMKNPEKTAEAFFEFEGLPAYHTGDVGT
                     MTDEGLLLYGGRMDFQIKFNGYRIELEDVSQNLNKSRFIESAVAVPRYNKDHKVQNLL
                     AYVILKDGVREQFERDIDITKAIKEDLTDIMMSYMMPSKFLYRDSLPLTPNGKIDIKG
                     LINEVNKR"
     gene            complement(32705..32836)
                     /locus_tag="VYO11_000675"
     CDS             complement(32705..32836)
                     /locus_tag="VYO11_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HEV1595273.1"
                     /translation="MKQRKELYLFLGRTALYFLIFLGLLYFFSYLGQGQGSFIYNEF"
     gene            complement(33150..34328)
                     /locus_tag="VYO11_000676"
     CDS             complement(33150..34328)
                     /locus_tag="VYO11_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEV1595274.1"
                     /translation="MSNSFVKLLVSQLFANLADIFFRVTIIANIYIISKSVIATSLVP
                     ILIGISSFVASLLVPLVTKRLALNRVLSLSQFGKTILLAILVGMFTVMQSVAPLVTYL
                     FVVAISILDGFAAPVSYAIVPRYATDLGKANSALSMTGEAVQLIGWGLGGLLFATIGL
                     LPTTFIILVLYIISSFLMLFLPNAEVEVLESETNLEILLKGWKLVARNPRLRLFVSAN
                     LLEIFSNTIWVSSIILVFVTELLNKTESYWGYSNTAYSIGIIISGLIAFRLSEKFLAA
                     KWESILFPLVAMAIVTLTILYFPNAQMFLLFSALVGMLSQLKEVPESVFLQETVEENH
                     LVNVYSVLEVISTLAFSVFVLLMSYITESFGISISFWLSAICLMIEAILIYIRRDYFK
                     "
     gene            complement(34785..36062)
                     /gene="ltrA"
                     /locus_tag="VYO11_000677"
     CDS             complement(34785..36062)
                     /gene="ltrA"
                     /locus_tag="VYO11_000677"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HEV1595275.1"
                     /translation="MSKLLDKILSRENMLEAYNQVKSNKGSAGIDGMTIEEMDNYLRQ
                     NWRLTKELIKQRKYKPQPVLRVEITKPNGGIRQLGIPTVMDRMIQQAIVQVISPICEP
                     HFSDTSYGFRPNRSCEKAIMKFLEYLNDGYEWIVDIDLEKFFDTVPQDRLMSLVHNII
                     EDGDTESLIRKYLHSGVIINGQRHKTLVGTPQGGNLSPLLSNVMLNELDKELEKRGLR
                     FVRYADDCVITVGSEAAAKRVMYSASRFIEKRLGLKVNMTKAKITRPRELKYLGFGFW
                     KSSDGWKSRPHQDSVRRFKLKLKKLTQRKWSIDLTRRIEQLNLSIRGWINYFSLGNMK
                     RIVASIDERLRTRLRVIIWKQWKKKSRRLWGLLKLGVPKWIADKVSGWGDHYQLVAQK
                     SVLKRAISKPVLEKRGLVSCLDYYLERHALKVS"
     gene            37150..37494
                     /locus_tag="VYO11_000678"
     CDS             37150..37494
                     /locus_tag="VYO11_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000041363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1595276.1"
                     /translation="MSKMFKCMCLLVMSVFCMSSISPSLVVFADDSLSANSKVVSGEA
                     QFENGSSVRFGDTQVNILSDEVLEVVNPDGSVDTIERRADGVYINGAFYMAYQKNEID
                     LNISFRSYDPNV"
     gene            37549..37809
                     /locus_tag="VYO11_000679"
     CDS             37549..37809
                     /locus_tag="VYO11_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1595277.1"
                     /translation="MTGAGISYMIGRIGALLGGPWGAIIGGAYFGIQAYQSYLDSQSP
                     YPYYITSTYIHVAQRKWKFITEYYRNSNYTGYVKTVTTYVNF"
     gene            complement(37896..38042)
                     /locus_tag="VYO11_000680"
     CDS             complement(37896..38042)
                     /locus_tag="VYO11_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004247184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1595278.1"
                     /translation="MLVEFHKSQGTLETPEAQAEIAQKREEIEQRRAELEDKKQELLN
                     RLNK"
     gene            complement(38290..38994)
                     /locus_tag="VYO11_000681"
     CDS             complement(38290..38994)
                     /locus_tag="VYO11_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HEV1595279.1"
                     /translation="MMNELFGEFLGTLILILLGNGVVAGVVLPKTKSNSSGWIVITMG
                     WGIAVAVAVFVSGKLSPAHLNPAVTIGVALKGGLPWASVLPYILAQFAGAMLGQILVW
                     LQFKPHYEVEENAGNILATFSTGPAIKDTVSNLISEILGTFVLVLTIFALGLYDFQAG
                     IGTFAVGTLIVGIGLSLGGTTGYALNPARDLGPRIMHSILPIPNKGDGDWSYAWIPVV
                     GPVIGAALAVLVFSLF"
     gene            complement(39064..40890)
                     /gene="glpO"
                     /locus_tag="VYO11_000682"
     CDS             complement(39064..40890)
                     /gene="glpO"
                     /locus_tag="VYO11_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HEV1595280.1"
                     /translation="MEFSKKTRELSIKKMQERTLDLLIIGGGITGAGVALQAAASGLE
                     TGLIEMQDFAEGTSSRSTKLVHGGLRYLKQFDVEVVSDTVSERAVVQQIAPHIPKPDP
                     MLLPVYDEDGATFSLFRLKVAMDLYDLLAGVSNTPTANKVLSKDQVLERQPNLKKEGL
                     VGGGVYLDFRNNDARLVIENIKRANQDGALIANHVKAEGFLFDESGKITGVVARDLLT
                     DQVFEIKARLVINTTGPWSDKVRNLSNKGTQFSQMRPTKGVHLVVDSSKIKVSQPVYF
                     DTGLGDGRMVFVLPRENKTYFGTTDTDYTGDLEHPKVTQEDVDYLLGIVNNRFPESNI
                     TIDDIESSWAGLRPLIAGNSASDYNGGNNGTISDESFDNLIATVESYLSKEKTREDVE
                     SAVSKLESSTSEKYLDPSAVSRGSSLDRDDNGLLTLAGGKITDYRKMAEGAMERVVDI
                     LKAEFDRSFKLINSKTYPVSGGELNPANVDSEIEAFAQLGVSRGLDSKEAHYLANLYG
                     SNAPKVFALAHSLEQAPGLSLADTLSLHYAMRNELALSPVDFLLRRTNHMLFMRDSLD
                     SIVEPVLDEMGRFYDWTEEEKATYRADVKAALAQNDLAELKN"
     gene            complement(40932..42440)
                     /gene="glpK"
                     /locus_tag="VYO11_000683"
     CDS             complement(40932..42440)
                     /gene="glpK"
                     /locus_tag="VYO11_000683"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HEV1595281.1"
                     /translation="MSQEKYIMAIDQGTTSSRAIIFNKKGEKVSSSQKEFTQIFPQAG
                     WVEHNANEIWNSVQSVIAGAFIESGVKPNQIEAIGITNQRETTVVWDKKTGLPIYNAI
                     VWQSRQTAPLAEQLKSQGYVEKFHEKTGLIIDAYFSATKVRWILDHVEGAQERAEKGE
                     LLFGTIDTWLVWKLTDGAAHVTDYSNAARTMLYNIKELKWDDEILEILNIPKAILPEV
                     RSNSEIYGKTAPFHFYGGEVPISGMAGDQQAALFGQLAFEPGMVKNTYGTGSFIIMNT
                     GEEMQLSENNLLTTIGYGINGKVYYALEGSIFIAGSAIQWLRDGLRMVENSPESEKYA
                     RDSHNNDEVYVVPAFTGLGAPYWNQNARGSVFGLTRGTSKEDFIKATLQSIAYQVRDI
                     IDTMQVDTQTAIQVLKVDGGAAMNNFLMQFQADILGIDIARAKNLETTALGAAFLAGL
                     SVGYWKDLDELKLLNETGELFEPSMNESRKEQLYKGWKKAVKATQVFAEVDD"
     gene            complement(42599..44026)
                     /locus_tag="VYO11_000684"
     CDS             complement(42599..44026)
                     /locus_tag="VYO11_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV1595282.1"
                     /translation="MYLGDLMEKAECGQFSILSFLLQESQTTVKAVMEETGFSKATLT
                     KYVTLLNDKALDSGLELAIHSEDENLRLSIGAATKGRDIRSLFLESAVKYQILVYLLY
                     HQQFLAHQLAQELVISEATLGRHLAGLNQILSEFDLSIQNGRWRGPEHQIRYFYFCLF
                     RKVWSSQEWEGHMQKPERKQEIANLEEICGASLSVGQKLDLVLWAHISQQRLRVNACQ
                     FQVIEEKMRGYFDNIFYLRLLRKVPSFFAGQHIPLGVEDGEMMIFFSFLLSHRILPLH
                     TMEYILGFGGQLADLLTQLIQEMKKEELLGDYTEDHVTYELSQLCAQVYLYKGYILQD
                     RYKYQLENRHPYLLMEHDFKETAEEIFHALPAFQQGTDLDKKILWEWLQLIEYMAENG
                     GQHMRIGLDLTSGFLVFSRMAAILKRYLEYNRFITIEAYDPSRHYDLLVTNNPIHKKE
                     QTPVYYLKNDLDMEDLAGIRQLLFT"
     gene            44191..45063
                     /gene="hslO"
                     /locus_tag="VYO11_000685"
     CDS             44191..45063
                     /gene="hslO"
                     /locus_tag="VYO11_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000357853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HEV1595283.1"
                     /translation="MDKIIKTISESGAFRAFVLDSTETVRTAQEKHQTQASSTVALGR
                     TLIASQILAANEKGNTKLTVKVLGSSSLGAIITVADTKGNVKGYVQNPGVDIKKTATG
                     EVLVGPFVGNGQFLVITDYGAGNPYNSITPLISGEIGEDLAFYLTESQQTPSAVGLNV
                     LLDEEDKVKVAGGFLVQVLPGAKKEEIARFEKRIQEMPAISTLLESDDHIEALLKAIY
                     GDEAYKRLSEEEIRFQCDCSHERFMNALASLPSSDLQEMKEEDHGAEITCQFCQTTYN
                     FDEKDLEELIRDKS"
     gene            45050..46030
                     /gene="dusB"
                     /locus_tag="VYO11_000686"
     CDS             45050..46030
                     /gene="dusB"
                     /locus_tag="VYO11_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HEV1595284.1"
                     /translation="MTNLNTPFMIGNVEIPNRTVLAPMAGVTNSAFRTIAKELGAGLV
                     VMEMVSDKGIQYNNEKTLHMLHIDEGENPVSIQLFGSDEDSLARAAEFIQENTKTDIV
                     DINMGCPVNKIVKNEAGAMWLKDPDKIYSIINKVQSVLDIPLTVKMRTGWADPSLAVE
                     NALAAEAAGVSALAMHGRTREQMYTGHADLETLYKVAQALTKIPFIANGDIRTVQEAK
                     QRIEEVGADAVMIGRAAMGNPYLFNQINHYFETGEILPDLTFEDKMKIAYEHLKRLIN
                     LKGENVAVREFRGLAPHYLRGTSGAAKLRGAISQASTLAEIEALLQLEKA"
     gene            complement(46260..>46546)
                     /locus_tag="VYO11_000687"
     CDS             complement(46260..>46546)
                     /locus_tag="VYO11_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HEV1595285.1"
                     /translation="YNGSWYYLNSNGAMVTGWLQNNGSWYYLNANGSMATDWVKDGDT
                     WYYLEASGAMKASQWFKVSDKWYYVNGSGALAVNTTVDSYRVNANGEWVN"
BASE COUNT        13975 a        10015 c         8294 g        14262 t
ORIGIN      
        1 ataataacat aaaattgtgc taaacatcat aatttatatt attttccgag aaattatagc
       61 cattgacatt acctaggaat tgcgttataa catacatgta agcggtaccc aaaatggtgc
      121 caagtcaaaa tttttaagga ggaaaataca tgtcttctca tccaattcag gtcttctcag
      181 aaattgggaa actgaaaaaa gttatgttgc accgtccagg caaggagtta gaaaacttgt
      241 tgccggacta tcttgaaagg cttctttttg atgatattcc tttcttggaa gatgctcaaa
      301 aagaacatga tgcatttgcc caagctcttc gcgatgaagg aattgaggtt ctctacctag
      361 aacaactcgc tgctgaatca ttgacctctc cagaaatccg cgatcaattt atcgaggaat
      421 acttagacga agccaacatc cgtgatcgtc aaaccaaggt tgctattcgt gaattacttc
      481 acggcatcaa ggacaaccaa gaattggttg aaaaaacaat ggctgggatt caaaaagttg
      541 aattgccaga aattcctgac gaagctaaag atctaactga cttagttgaa tcagagtatc
      601 catttgcaat tgacccgatg ccaaacctct atttcactcg cgacccattt gcaacaattg
      661 gaaacgccgt atcgcttaac cacatgtttg cagacactcg taaccgtgaa acactctacg
      721 gtaagtatat cttcaaatac cacccaatct atggcggaaa agtggatttg gtctacaacc
      781 gtgaagaaga tacgcgtatc gaaggtggag acgagctagt tctttctaaa gacgtccttg
      841 cagtaggtat ctctcaacgt acagacgcag cttctatcga aaaacttttg gtcaacatct
      901 tcaagaaaaa tgttggcttc aagaaagttt tggcctttga atttgctaac aaccgtaaat
      961 tcatgcactt ggatactgtc ttcactatgg tagactatga caagttcact attcacccag
     1021 aaatcgaagg cgaccttcac gtttactcag ttacttacga aaacgaaaaa cttaaaattg
     1081 ttgaagagaa aggtgactta gctgaacttc ttgctcaaaa ccttggtgta gaaaaagttc
     1141 atttgattcg ttgcggtggt ggcaatatcg tagcagctgc gcgtgaacaa tggaacgacg
     1201 gttctaacac tttgaccatc gcacctggtg tggtagttgt ttatgaccgc aataccgtga
     1261 ccaataagat tttggaagaa tacgggcttc gcttgattaa gattcgcgga agtgaattgg
     1321 ttcggggccg tggtggacct cgttgtatgt ctatgccatt tgaacgtgaa gaagtgtaat
     1381 agctgttcgg cattcgtcaa tagaaaatgt aaaaaataga aagaggaaat aataaaatga
     1441 taaattcagt attccaagga cgcagcttct tagcagaaaa agactttacc cgtgcagagt
     1501 tagaatacct tattggtctt tcagctcact tgaaagattt gaaaaaacgc aatattcaac
     1561 accactacct tgctggcaag aatatcgctc tcctatttga aaaaacatct actcgtactc
     1621 gtgcagcctt tacaactgcg gctatcgacc ttggtgctca cccagaatac ctcggagcaa
     1681 atgatattca gttgggtaaa aaagaatcta ctgaagatac tgctaaagta ttgggacgta
     1741 tgtttgacgg gattgaattc cgcggattca gccaacgtat ggttgaagaa ttggcagaat
     1801 tctcaggcgt tccagtatgg aacggtctaa ctgacgaatg gcacccaact caaatgctcg
     1861 ctgactactt gactgttcaa gaaaacttcg gtcgcttgga aggcttgaca ttggtatact
     1921 gtggtgatgg acgtaacaac gttgccaaca gcttgctcgt aacaggtgct atccttggtg
     1981 tcaatgttca catcttctca ccaaaagaac tcttcccaga aaaagaaatc gttgaattag
     2041 cagaaggatt tgctaaagaa agtggcgcac atgttctcat cactgaagat gctgatgaag
     2101 cagttaaaga tgcagacgtt ctttacacag acgtttgggt atcaatgggt gaagaagaca
     2161 aattcgcaga acgtgtagct cttcttaaac cttaccaagt caatatggac ttagttaaaa
     2221 aagcaggcaa tgaaaacttg atcttcctac actgcttgcc agcattccac gatactcaca
     2281 ctgtttatgg taaagacgtt gctgaaaaat ttggtgtaga agaaatggaa gtaacagacg
     2341 aagtcttccg cagcaagtac gctcgccact tcgatcaagc agaaaaccgt atgcacacta
     2401 tcaaagctgt tatggctgct acacttggta acctttatat tcctaaagta taattttaga
     2461 taataaaccg tctaccaaca gctatgaggg ctgcgactaa tagctttagt ccggtcctct
     2521 tttatgtaat ggtaatctat tatttcttat aaaatatgtg aaaaatcatt aaattgaaat
     2581 ctaaacgcat tctattgagt gtgataaagg agaatttatg gcaaatcgta aaattgtagt
     2641 agctttggga ggaaatgcga ttctttcttc tgacccatca gcaaaggctc aacaagaagc
     2701 tttagttgaa acagctaagc atcttgtaaa attgattaaa aatggagatg atctgattat
     2761 cactcacggt aatggacctc aagttgggaa tctcttgctc caacatttgg catcagactc
     2821 tgaaaagaac cctgccttcc cactcgactc acttgtcgct atgacagaag gtagcatcgg
     2881 tttctggttg aaaaatgctt tgcaaaatgc tctcttggat gaaggcatcg aaaaaaatgt
     2941 tgcctctgtt gtaacgcaag ttgtcgtaga taaaaatgat ccagcttttg ttaacttgag
     3001 taaaccaatc ggtcctttct attcagaaga agaagcaaaa gcagaagccg aaaaaagcgg
     3061 agcgactttc aaggaagatg ctggccgtgg ctggcgtaag gtcgttgcct caccaaaacc
     3121 tgttgacatc aaagaaattg aaaccatccg tactctttta aataatggtc aagtcgtcgt
     3181 agctgcaggt ggtggcggta ttcccgtcgt caaagaaaac aatggacatt tgactggtgt
     3241 cgaagcggtt attgataaag acttcgcttc ccaacgtttg gcagaattgg ttgatgcaga
     3301 cctcttcatc attttgacag gtgtagatta tgtatttgtt aactacaaca agccaaacca
     3361 ggaaaaattg gaacatgtga atgttgccca gctggaagaa tatatcaaac aagatcagtt
     3421 tgcaccaggt agcatgcttc caaaagtaga agcagctatc gcttttgtca atggtcgtcc
     3481 agaaggaaaa gcagttatta cttcccttga aaatctaggc gccttgattg aatctgaaag
     3541 cggaacaatt attgaaaaag gataagttgt tttactaata agatgtattc tatttctagt
     3601 atctttatat caaattagaa attattcttg aaaacatgta caatatttca aaagatatta
     3661 gttttttaga ctttaatatg gtaaaacaaa tataaataga aagcgttttc ttgaatgttt
     3721 atttaagaaa gtagttggtt ttttacactt tgttagacat caggaggaaa aacaaatgag
     3781 tgaaaaagct aaaaaagggt ttaagatgcc ttcatcttac accgtattat tgataatcat
     3841 tgctattatg gccgtgctaa cttggtttat ccctgcgggg gcctttatag aaggtattta
     3901 cgaggctcat cctcaaaatc cacaagggat ttgggatgtc ctcatggcac cgattcgggc
     3961 tatgctaggt actcatccag aggaaggttc gctcattaaa gaaacgagtg cagcgattga
     4021 tgtagccttc ttcatcctta tggttggtgg tttccttggc attgtcaaca aaactggtgc
     4081 tcttgacgta gggattgcct ctatcgtgaa gaagtataag ggccgcgaaa aaatgttaat
     4141 tttggtactg atgcctttgt ttgccctcgg tggtacaact tatggtatgg gtgaagaaac
     4201 aatggccttc tatccactcc ttgtgccagt tatgatggcc gttggttttg atagcctgac
     4261 tggtgttgca attattttgc tcggttctca aatcggctgt ttggcatcta ctctgaatcc
     4321 atttgcgaca ggtattgctt cagcgactgc gggagttggt acaggggacg gtatcgtact
     4381 tcgtctgatc ttctgggtta ccttgactgc tcttagtact tggtttgttt accgttatgc
     4441 ggataagatt caaaaagatc cgactaagtc actggtttat agtactcgca aagaagattt
     4501 gaaacacttt aacgtagaag aatcttcatc tgtagaatct acacttagca gcaaacaaaa
     4561 atcagttctc ttcttatttg tgttgacatt catcttgatg gtattgagct tcattccatg
     4621 gacagacctt ggcgttacca tttttgatga ctttaatgct tggttgactg gtcttccagt
     4681 tattggtaat attgtcggtt catctacttc tgcactaggt acttggtact tcccagaagg
     4741 cgcaatgctc tttgccttta tgggtatcct gattggtgtt atttatggtc ttaaagaaga
     4801 taagattatc tcttccttca tgaatggtgc tgctgacttg ctcagtgttg ccttgatcgt
     4861 agcgattgct cgtggtattc aagttatcat gaacgacggt atgattaccg atacaatcct
     4921 caactggggt aaagaaggct tgagcggtct atcttcacaa gtctttatcg ttgtaactta
     4981 tatcttctat ctacctatgt cattcttgat cccatcttca tctggtcttg ccagcgcaac
     5041 tatgggtatc atggctccac ttggagaatt tgtaaatgtc cgtcctagct tgattatcac
     5101 tgcttaccaa tctgcttcag gtgtcttgaa cttgattgca ccaacatctg gtattgtgat
     5161 gggagctctt gcacttggac gtatcaacat tggtacttgg tggaaattca tgggcaaact
     5221 cgtagtcgct attattgtag tgaccatcgc ccttcttctc cttggaacct tccttccatt
     5281 cctataaaat agtgagtgag gtgattccat gaaaatagat ataacaaatc aagttaaaga
     5341 tgaatttctt atatcattaa aaaccttgat ttcctatcct tcagtactca atgaaggaga
     5401 aaatggaaca ccttttggac aagcaatcca agatgtccta gaaaaaactt tagagatttg
     5461 tcaagacata ggtttcacta cctatcttga ccctaaaggt tattacggat atgcagaaat
     5521 cggtcaggga gcagagcttc tggccattct ctgtcatttg gatgttgttc catcaggtga
     5581 tgaagcagat tggcagacac cgccatttga agcaactatc aaagacggct gggtattcgg
     5641 acgtggtgtc caagatgata aaggcccttc gctcgcagct ctctatgcag taaaaagctt
     5701 gctggaccaa ggtattcagt tcaaaaagcg cgtacgcttt atctttggta ccgatgagga
     5761 aaccctctgg cgctgcatgg cacgctacaa taccatcgaa gaacaggcca gtatgggctt
     5821 tgcacctgac tcatcttttc ctctgaccta tgctgaaaaa gggcttctac aggtcaaact
     5881 tcatggccct ggatcggatc aactagagct tgaagtagga ggcgccttta acgttgtacc
     5941 agacaaggcc aactaccaag gtcccctcta tgaacaggtt tgtaacgatc tcaaagaagc
     6001 tggttatgat taccaatcca ctgaacaaac cgtaacggtt ctcggagtgc caaagcatgc
     6061 taaggatgct agtcaaggta tcaatgctgt catccgacta gctaccattc ttgctcctct
     6121 ccaagaacac cctgctctca gctttcttgc aacacaagca ggtcaagacg gcacaggaag
     6181 acaaatcttt ggtgatatag cagatgaacc ttctggtcac ctatccttta atgtcgcagg
     6241 tctcatgatc aatcatgaac gttctgaaat ccgtattgac attcggactc ctgtcttagc
     6301 tgataaggaa gaactagtag agttgcttac aagatgtgca caaaactacc aactccgcta
     6361 cgaagagttt gactatctag cgcctctata cgtcgcaaaa gacagtaaac tcgttagcac
     6421 actgatgcaa atctaccaag aaaagactgg cgataacagt cctgctattt catccggtgg
     6481 tgccactttt gctcgcacca tgccaaattg tgtagccttc ggcgccttat tcccaggagc
     6541 gaagcaaaca gaacatcagg caaatgaatg tgccgttcta gaagatttgt accgtgctat
     6601 ggatatttat gccgaagccg tctatcgact tgcaacttaa tcaggcaact gtttctacca
     6661 aaaaaaatcg accgattaat gaactgcacc ccaaaagtta gacagaataa atctaacttt
     6721 tggggtgttt tattatgaaa ttgagttatg aagataaagt tcagatctat gaactaagaa
     6781 agcaaggaca aagcttcaaa cagctttcaa aaagatttgg tgtggatgtt tctggtctaa
     6841 agtcatctga atctttgaga tgagctttat aaatcgcttt tttcagtttt tgcactggta
     6901 tttcgataaa ctcaaacttt ttagccgttg tattgcctga ttttatagta tgttgaaact
     6961 agaatagtac acctctactt ctaaaacatt tttagaaatc aatttgactg tcctgattga
     7021 tttgtcctgt tcttatttca ttttactata tttgagccac ttcgtcttta acggctttat
     7081 tcataagctc ttgtaatttt tctttactat caattacttc tgattttccg ttgtaattta
     7141 ttgtaatagg ttttaactta cctaatttct cgacacgctc attaatttga tcttttttga
     7201 aggctgcata tgtttttcct aagatttttt cgaaaatata tttatcagat agcggtttgc
     7261 cttcttcttc agcttggttt ttgtattgat ttgaaacata aggaacaaat ccttcatagt
     7321 aacctaatgc tcccataagt tcaaaagctt gttttctaat tcaaaccatt gcaactcaga
     7381 tttcagcttt tcagataaat cctgctcatc caaataatga cttgaaatta gtgctgaact
     7441 cgtttctgta tcctgtacag gctgagcacc cataccagca aaaaaataaa ctcgttccta
     7501 gcaagaccga acaagctcct attgcatatt tcctcaaaga aaaacgctgc tttctctcaa
     7561 attgaaattc tttcatccca tctcccatca ttcattatta ctgtatattt tgtatatcag
     7621 aaatagtttg tattcacaaa tctttctagt tattccctta tcattcctaa ttaagggaga
     7681 taacatacaa taatttttag ttaaatgtat atcgatgttt tttgtttttc ttaataaacg
     7741 caatacaaaa agagcctgtt gccaagctct ttatactcaa tgaaaatcaa agagcaaact
     7801 aggaaactag ctacaggttg ctcaaaacac cgttttgagg tagtagataa gactgacgaa
     7861 gtcagctcaa aacactgttt tgaggttgca gatagaactg acgaagtcag taacatctat
     7921 acggcaagac gacgctgacg tggtttgaag agattttcga agagtattag tctattattt
     7981 cttctcagcg cgaagggctg acaagatttg tgtacggata tcatccacac catttggagt
     8041 atttggtaaa aagatggttt gatttccttt agaggcaaag gtattcaagg tatccaaata
     8101 ctggttggtc aagaggatag acatgatttg ttcttctgtc atgccaacat tggcttcctt
     8161 gagttcggtg atagactctg ccaatccatc cacaatcgcc ttacgttgtt gggcaatccc
     8221 cacaccatga aggcggtctt tttctgcttc tgcttcagct gcagtgacaa ttttaatctt
     8281 gtcagcttcc gccaattctt gtgctgcgac ccgcttacgt tgcgccgcat tgatttcatt
     8341 catggattgc ttaacttctg catccggttc gaccttggta atcaaggttt tcacgataat
     8401 gtagccgtaa gtggtcattt cttctgctac ttggtgttga acctcaaggg caatctcatc
     8461 ttttttctca aacaattcat ccaaggttaa ttttggaaca gaagagcgaa gagcatcttc
     8521 gatataagat ttaatctgag attctggacg tatgagttta tagtaagcat ctgtcacgct
     8581 ctgctcgttg acacggtact gagtcgctac attcatcata acgaacacat tgtccttggt
     8641 cttagtctca accacaatat cactttgcaa caagcgcaac tgaatccgtg ctgcaatcga
     8701 gtcaatccca aaaggcaagc gaatatgaat accgctatta gcaacctttt ggtatttccc
     8761 aaagcgttca ataatcgcca ccgactgctg acgaaccaca taaactgtac tcagtgtgac
     8821 tatcaccaat aggagcacac aaacaatcag aaaaatcatg aaaaatattg ccataatgga
     8881 acctccacaa gtatttttct agtattatag cacatttaaa gaaggctgtg ccgtttttac
     8941 tgcgattttt tctgaaatgt caataattag aggtgaattg tcctattgtc gtccaatcct
     9001 tgctaaaata actctttata aaaggcaatc gtttcttcta aggttggcat aaatggattt
     9061 cctggtgcgc aggcatcaat caaggcattc ttagaaaggt attcaaagtc gaaatctttt
     9121 tcttcaatac caagttcagt cagtttctta ggaataccta ctgtctcaga aagcttctca
     9181 atctcagcaa tcgcataatc ggcacattct tgatctgatt taccttctac atgaagtccc
     9241 aaggctttgg caacattgcg gaaagcttct ggtacacgtt tagcattttc acgttctata
     9301 actggtagca acatggcaca gcaaacacca tgtggcaaat tatatactgc accgagttgg
     9361 tgagccattg agtgaacata gccaagacca gcattattaa agctcatacc accaaggaag
     9421 atggcattga ccataccttc acgcgcttca atatcatgtc cgtttgctac agcacgagga
     9481 agatattcct tgataagctc aatagcacca atagacagtt tcttggttac atcataagca
     9541 ccaggtgtta ccaaagcttc aacagcgtga gtcagagcat ccataccagt agcagcagtc
     9601 aaggcttgag gtttggaaag catgagttca gggtcattga cagaaatcaa ggcaaggcta
     9661 ttcttgtcaa ccattaccat cttaaccttg cgttcttcat cagtaatcac atagttaatg
     9721 gtaatttctg ctgatgtacc tgccgtagta ttgatagcta caacaggaag gcctttttta
     9781 gcagacttat gaagcccttc ataatcctgt ggttttccac catttgtaac catgatagaa
     9841 atacaactag ctgcatcctg tggagaaccc ccgccaagac tgatgataaa atcacatcca
     9901 tgttcttgca aagcagctac cccatctgtg acattcttac aagtagggtt tggctctaca
     9961 tcgctaaaga tgacatattc gattccttct gtatccagtg gttttaaaac cttaggtaaa
    10021 atgtcactgc cttcgatgta cttatctgtc accaaaagtg cctttttata gccaagttcc
    10081 ttgatataag gacccacttc atttacaaca ccttttccaa taaggttgac tgccggaaca
    10141 taaaatgtag ccatataatt ttcctcctgc gcctttgcgc tatctattta acatcattat
    10201 attacttttt gtattcgttt ttaattattt gtgaattgtt taacaaatct ttttaaaagg
    10261 ataggaggga cgtaagttca cctcctatat aaacaagttt tatttatgta gtggtcccaa
    10321 caactgacat gcacgatagt ctgctgattc tagatcttct gttccaaata aggaccaatt
    10381 tttaggtcta aagatatctt cctcaggtac attatgcata ttgacaggaa ttctcaacat
    10441 agaagccaag gtaatcaagt ctgctccaat gtgtccatat gttatggctc cgtgattagc
    10501 tccccaatta ttcatgacgt catagacaga cttgaaagca ccttttcctg tcaaacgtgg
    10561 agcaaaccaa gtagttggcc atcctggatc tgtacgatta tctaaagtat ggtgaacatc
    10621 ttcaggaagt tcaagtgtgt aaccttctgc aatttgtaac actggaccaa ccccttttag
    10681 aagattgaga cgtaccattg ttactggcat atcccccttc gtcaagaaac gagttgagaa
    10741 tcctcctcca cggaagtatt cgcggtttgc tggtgggaag tctgtatttt caagcatagc
    10801 ctgcacttca ctttcttcca actcccagaa tggtttcata acaggtttgc catctcgagt
    10861 agcttgacct gtaccatcca atgtacaaga accagagttg attagatgta agaagccagc
    10921 tgcagcacga ccctctaaag tatgtcccgt tacacgttta acagcctctg gactccaata
    10981 agtacgcaca tcagcaaata tttgtggagt atttgttaat agataattaa agagcataga
    11041 cacaccattt agtgaatcat tctctgtcgc aaatacaaat ggttttcgaa taccattcca
    11101 gtcaaactga gtattgagga aagtttccat aaagtcccca tttgggaaat gatctgtcca
    11161 ctggcgttga ccttggaaac cagctactaa agcatggtga ccaactgctt cttcttcaaa
    11221 accaagttca gcaagtcttg ggttaccaac cattaagtca cgtccaatca tgaacatctt
    11281 aataacaaat tcccattgtt tttctttctc ttctttagaa agaatcaaat cctcacgatt
    11341 tcggtcaacc ccttctttga tatgttcttt tacccaaacc atagcacgtt cgaactcttc
    11401 tgggtcataa ataccacggt ccatacggcg cgtgaactcc gtcatatcta ccgattcatt
    11461 tcgcattcct aagtattctt ggaagaaatc tggatttaca atagaaccac caatccccat
    11521 cgaaacacta cccattgata ggtaagcagt gtctctcatc aagccagttg caagagctgc
    11581 acgcgcataa cgtaaaagtt tttctttgac atcttctgga atagctgtgt cactagcttc
    11641 ctgaacatct cttccataaa tcccaaaggc tggaatccct ttttgagcat gtgaagctag
    11701 tacagctgca agatagacag ctcctgggcg ttctgtccca ttaaatcccc aaatagcatg
    11761 aggaatatct ggagacatat ccatagtttc actaccataa caccagcatg gtgtaactgt
    11821 aattgttgcg caaacatttg attttttaaa caactcatgg gaagctgcag cctctggaac
    11881 acgaccaatg gtagatggag aaatcacaca ttccacaggt tccccatctg gatatttcaa
    11941 tgtgcttgaa atcaaatctg ccacactttt agccatgttc attgtttgta cttcaagtga
    12001 ttcgcgtaca ccttgacgac gaccatcaat agtcggacga atcccaatac gtggatgttg
    12061 aatcatacta ttttcctctt atttttctgt ttctttcata ctaccgatga taatttttaa
    12121 aattacttat aagtataaac ctctacctct gccaaactta aaggaattcc tgcgtttctc
    12181 aaagaaattc taaccttttt tcccttcagc ccttttaagt ctatggatag attattgctt
    12241 tctaaactgt caatatgttg tttaaaaact tcatgattat ttgaatcata tataataata
    12301 tcaaaatttg ataatctctg aatttcagca tctgttctat tataaataat taacttttct
    12361 aattcttcgg tttgtgctaa atctatctcc caccatgaag gagaatctcc tttggtatga
    12421 gtcactgaat gatgaccata atctccgttt ttatttccat caactgctag acgagaaaaa
    12481 ccattgtaat ccgttgaact ctgtcgagtt tctttggtta atgcaatatt agaaagtttc
    12541 ttcggagttc tctttgaacc atagacttca acttccgcta aacttaacgg aatagctgct
    12601 gattttaatt ctattttgac tagcttagcc cctacagaag gtacttttaa agataacaaa
    12661 ccatcaacta ctttatcaaa atgtcttcta aaaacttctt ctcctgatga agatagaaaa
    12721 ataacatcaa aattagataa acgctgaggt tcggcatctg ttctattata aatatcaact
    12781 ttagaaaccg taaactcttc tcccagatcg acctgccacc aagcgttaga atctgcctta
    12841 gtatgagtca ccgaatgatg tccgtaatct ccatctttat taccatcaac tgctaaagca
    12901 gctacaccct cataattggt tgaactttga gtagctacct tatttgtaga gactacttta
    12961 tcttctgtta ttttatctat atcctcttca gattgcttac catctgattc tctaaaaacc
    13021 tctacttctg ctaaactcaa aggcactcca ctcgttagta atttaacttt aatatacctt
    13081 gctccttttt ctttgaaatc tagactaaca gattcacccg acaaattatt aacatgtttc
    13141 ttagcaactt cgtttctatt attgtcatat agaatcacat caaaattaga tagacgttga
    13201 gtctcagcat ctgtgcgatt ataaatttta acaagcccaa ctttatccat ttttttcaaa
    13261 tcgacttccc accaagaagg attatctgcc ctagtgtgtg ttaccgaacc agagttaaaa
    13321 ttaccatttc tgttaccatc cacagctcta ttagggtctc cattgtaatc tacagaactt
    13381 tgtgttgttg gttttgcata tgctatattc aaattaccat cattaaattt atctggtgtt
    13441 gggaaaggga ctgggcctgt cccttcagta tttatagaca tctctaccat tccattatga
    13501 ttaaccgtaa tggtataaac atgggtattc tcatcccaat tttctgtata agtataatga
    13561 tttttatcgc cacttatatt tatctgaggt ttatgaccag tatgcccttt taatgtaagt
    13621 gttgttgtcc taaagtcatt atctacagga ttgatggaat aatttttgct tatccagttc
    13681 gctaactcta attcttcttt cttccaactt tttgatgcat caaaatttcc tgataatgcc
    13741 cacatagctg tcttatctgt cctgtaattg ttcaataaaa tatgtaaatt atttggattt
    13801 tctttaacaa cagcgtaagt atgtggcgtc aaatctaacg ataacgactt tgtattatta
    13861 gtatacatag gcaacattac ttgctgattt ttattgatat tagcattact attataaata
    13921 taccaggaat tacctacacg ctgagcatac ccatctcctt cataaagttt tggataaagc
    13981 gagtttaaat agttgacttt actagacaat tcctcactat ttttagtcaa aatttttgca
    14041 ttagggaata tagatgaaat cttttcctta tcaattttct catgtattac aggaagaata
    14101 tgatatctcc cattattata taaaggcatt gtttcatcat tcgaataaag tccttgataa
    14161 aatccgttta atgaactaat cctaccttct ccattccaaa atacagcttt tgttctattt
    14221 acaacttctt ccttacttgg agctggattt tgtatagcat gtctaaagaa aggaataata
    14281 cctttagtaa atgctggagt tggtacatca tttgtcataa atgtatacgc ggcacattca
    14341 aaattataaa ctgtgcctcc cccagtatat acattcatca tttccatagc aatcattgat
    14401 tctggttccg atgcatagga tctcatatcc ctagctcttc cagtttcaaa tgtgtttgta
    14461 taatgttttt cccaccattt ccatgtatct gttgatgagc cccagttatc acataagcca
    14521 ctcaaccaaa atccactaac gatagaatct gtacccgcat catctcttat tggcgtattt
    14581 ttagttgcca acaccaaatt tttatgatat ttttgactcg cttcaaagaa tgtcggatca
    14641 ttcataatag tttcccagaa ccatttttca tgatcatgcc agataaaatg cgctccatat
    14701 ttggcacaaa cttccaaata tttagcacta tgcggagcta actggttatt gtaaatccaa
    14761 taattctcaa tatttaaaac accttttaac acactatact tttggaattg ttcatctaac
    14821 cactctggag gaactgtatt acgctctcca gccgacataa taaccaagaa aactggaatg
    14881 tttagacttt gagcttcctc caacatcttg acataccatt ctctcaattc tttcgtatct
    14941 cgtggaatac aacttgttgg tttacagact tttgcaggat gaagttcaat cgctgcatat
    15001 ggttttacat cttcaggaat agcttcccat gctcccttca atgtgttccc ccaccataat
    15061 ccgttaccat tatcattgcc atacaacgga gaaagcaaca atggcgattc attattaatc
    15121 gtcgttctca tttgaacacg attatcagcc ttaactcctg ctaacaatcc aaaacataac
    15181 atcccaatac atacaaacag tattgtgatt aattttcttt ttattttttc tttattcatg
    15241 acttatacct aaaaatttaa ctcaataatt ttttctgaat taaataccaa ttcaatattt
    15301 tgtacatcag tatttttgcc atatattctt actcttactt tttgatcttt gtttcctcct
    15361 tccaatttta ggaatgttat atccccattt ttccaagcaa acgatacctt atatcctcct
    15421 cttactctga aacctttcac ttctccttct gaccaagcag aaggtaaagc tggaattagt
    15481 gataaccaat tatgatggct ctgtactaat aattcacaaa ttccactcac caaacctaaa
    15541 ttaccatcaa tttgaaatgg tggatggtca agaaataaat tgccaagagt cgcattattt
    15601 aacaaaccat taatctggtt ataagcaggt tcaccttgat atagtctcgc aaaaaaatga
    15661 atcagccatg cagcactcca acctgtttgt gtactagcat gcaaaccact tactaaccaa
    15721 ttattaatcg cttgctccct ctcctgtgaa gataaaaagt tagcgtttga taatctccta
    15781 ttgatagtga ttttagctgc ttctgctaat tccggagttt tatgaatatc aatctcatta
    15841 taaggataaa gcccaaatag aggtgaaatg tgtctatgcc caggctctac ttcttcataa
    15901 tcttctaacc attcttggat ttgcccatta ctacctattt ttgttttagg tagtttcttt
    15961 tttaactcct tcacacgact aataaaatcc gaattgtctc ctaattgttt tgcaatgcca
    16021 atgcatgaat cacaaaaata tcttagaatt tgattatcaa ttgtagatga tagacaagca
    16081 tttccttcaa taccattttt taagcgatat ttattttccg gtgagacact tggacctgtc
    16141 atcaagtagc catccacctc aaataaataa tcttcaaaga aaagaaatgc ttcttttatc
    16201 atttcaaaat gttccgtaag aatacgctca tcttggaaat ataaatagtg ttcccaaata
    16261 tgagtacata accatggaat agttaatacc caaattgcag cccccatggc atgagattgg
    16321 ggagccgtat cgccaaaacc atccgtatta tgatgtgctg taaaacctct agctccatac
    16381 attttcttag cggttagtct tcccggttct ctcattcttt cgagcatatc aaataatgga
    16441 tattctactt ctggtaaatc acatggacct accatccaat aattcatttg agtattaata
    16501 ttaatcgtat atttagaacc ccaaattgga tttaattcat cacaccatat tccttgaaga
    16561 ttgacaggta aaccattcgg ttgactagac gatattaaca gatatcttcc ataatgaaat
    16621 aacaagttag tcaagtagtt actatacttt ttagtgtttt caagaagtag attcgttgga
    16681 atgctaagac aatctttact atagtctagt ttaaaatcaa ctctattaaa ttgctcctga
    16741 tattttttta catgttcatc tttttctgta aagtaatcaa tactactaaa ttctccctga
    16801 agagaagaaa tatctatatt tccccaataa tccgtcattg atttgagata aagaaatacc
    16861 tctgtagcat tccgaataac tattgtctct cccaatacac ttacttcacc atccgtaact
    16921 ttagaatgac atactacttt aaactgaaca ccttttctac ctccagcaga ggccgacatt
    16981 aaaattgtac ttgaatccag tttagatact tcgtcattaa accgtttatt tctacccaaa
    17041 ttaatgttta aatttaatgt gttttgaact gatgacacta tacggcaaca taaaatattc
    17101 ttattaaaac tcgtaaaata ttctcttttt atttgtaaat tacaactatt aggctcaaac
    17161 acaacattag aaatagctgt atctaaatct agctctcttt catacaatga aagagcacaa
    17221 gactgaatat ctatatgctc aatgtaaagt tccccaagta attcatagtg gctttgatct
    17281 cttggggtag caaacattgt taactttatc aattcttcgg ctttctgaat ttctccatct
    17341 aaaagatatt cccgaatttt tttaagatgc aatagtgagt ctggattatt tctatctgac
    17401 tttcctctat accaaatagt ctcatcgttt agttgaatac attcttttgt agctgaacca
    17461 taaatcatac cacctaaatg accgttccca atcggcaagg cttcattcca atttgaggca
    17521 gctttcttat accataattt cactctttac ctctcttcca aaatggaggt gatatcccaa
    17581 ataccacctc cacactttct actacttcaa aattcctaaa acaactagga taactccaat
    17641 agccataaca ctaaagatta gtacaaccgg attctttcct tttctaatta atttacacat
    17701 taataaagtc aaagccatag ggataaatcc tggaattaat tttgtaatca tttcttgaac
    17761 agaaataaca agttccccct gcttaaattc taatccaaaa ttaataccaa ccattgatgg
    17821 aatcaaacca cccactagta ctagccctaa tgctgtcgcc atactcgtaa cgcgattcaa
    17881 tgttcctttt gtattatttt cttggataag actagaaccc ttagtatacc catatttcaa
    17941 accgaaatat ttaacaggaa tattaataat attaaacaat attaaggcga taaagatacc
    18001 taaagcaccg ccgtctttag aataagacgc accaatacta aaacagatag gaactagtgt
    18061 cagccagaac aaactatctc ctagaccagc cagtggcccc atcaagccaa ctttaatacc
    18121 agtaattgaa gctgcacctt catttccttc ttgttcttcc atagcggaag taactccaag
    18181 aataaatggt gccgctgttt gatgagtatt gaaaaactca aggtgacgtt tcattgcagg
    18241 agaagctgaa tctttgtctg ggtatagttt tttcaatact ggaagaattg tatatagaaa
    18301 acctaggttc tgcattctct catagttcca tgaagaacca tacataaaac ttcgtttgaa
    18361 aactttttta agttcaactt tagttacttt attattcatc atagatcaag atcctcctca
    18421 acatcactac ttgaagttgt ttcttgtggt ttacttccaa tcatatcgta gaagtatgct
    18481 accgcaatac caactagtga gatcccaatg gttgacattc ctccatacac agaacaaatg
    18541 aatccaatca acaagaatac ccacatattt ttcttgagca tcatatttaa aagcatacca
    18601 aaaccaattg aaggtagtaa agcacctgca gagttaagtc cctgcataac gattggtgga
    18661 accttagcaa acaagtctgc cacatattcc cctccaagca taatagctag gaaaattggt
    18721 acaattttaa ataacgtgat taaaaccaaa cttgaataat gataaaaacc gatctttgaa
    18781 taatctccgt ttttagcatc attatcagct tttttcacaa aataaacatc taaagttttt
    18841 gcaagaacat ccaactgttg ggtagcaact gcaattggaa ctgctatagc gataccagca
    18901 gtttctcctt gaccagataa aataccaaat gcagtaccaa taatcgcacc tgaaatagta
    18961 tctggtggag tgtaacctcc aatacctgtt acaccgagcc aagttaattc aagagctgaa
    19021 ccaataagaa caccttgggt gaaatctcct aagactaagc caaccattgc acttgtaact
    19081 aacggacggt ggatcataaa taacggtcca ttatagtcaa tagtggcaat aatcccaact
    19141 aatgtcacca gtaatgcttg tgtgaatagc atatactgta cctccttaaa ctatttttat
    19201 aaaaattttt ccaacattgt aactttatca ttaggaacca tttgaatttc aactctcgtt
    19261 cccttatcaa ctattttctt aaaataatat ttgtcttctt cacctagagc tacacctccc
    19321 gttacctttt cattttcctc cgttttactc atctgtccta cattgaggta ctccaatttt
    19381 aaatttcctt caatagaatc atacacatct tttggatttg tatatatcag cattgttctc
    19441 ttttttattg gcacagagtt taaaacttcc acaaaccgtt ttacactaaa gaaaacaatt
    19501 tttaaaccta ctggtgcaga aatctttaaa atagattgtc gtgttttatc ttctgagatg
    19561 cgatcattaa caatgataac ttgctcaata tcatactttt ttagccacgt agtgacaact
    19621 tgaccatgta ccagacggtc atcaatacga acaaactcta tagacataaa tcttcttcct
    19681 cctctacgtt aagttgttgt ttaacattaa acaaactatt ttgagcattg tgaacaattt
    19741 cttctaaatt gatttttgaa tcataatttg atattaattc cactaggaga ggaatattaa
    19801 accctgttac aatatcaact gaatccaaat ttaaaaaccg tgacaaagcc acattattag
    19861 gacttcctcc aatcaagtca gtcaaaacga taacctcttg atttgagtct aacagttcat
    19921 ccacttgatt tttaaaataa tgctcaaact ctacaatatt ctctccaggc atcaaaccta
    19981 atgtcctaac tctatcattt gttgtctcac caacaaacat ttctgcggtc atgagagctc
    20041 cgctagcaaa atcaccatga ctggcaacta aaattcctct attaaacatt ttctctttca
    20101 acaactactc ctttcttaag gataatatta gcataaagtg aagtttctcc tgtagcaaca
    20161 atagcataag ctttcttact acgttcataa aagtcttctc ttctaagata agtaatcgtt
    20221 ttaagatctg taccatgacc ttcaatcatc tgtctatagg taccccatat cttaggaata
    20281 tcatcacccg aaacaacgtt cataaactga attgaactat cgacgtaact atctaatggc
    20341 attaaataca gaatggaatc taataattct ggaatattta cgccatcaca acgaattagc
    20401 ttatttgcac atgaggcaga aggataattc gcgtcagcta atactatttc atctccatgt
    20461 cccatttcca ttaaagtctt caataaatct ggagaaatat ttttcggtat atgttttaac
    20521 attaatatcc tccctatttt ctctgaccgt atgttttaaa tttttctgcc atcaattcca
    20581 tctcctcatc aggaagaact actggctctc caaaattctt agctaaacaa taaatttttg
    20641 cacaatattc aacttcttca acaatattaa atgcattcaa taaattttgt gcacctgcta
    20701 aaattccatg attcgctagt aaaactgctc tacgaccttc cattgcttta gctgcattca
    20761 cagccaattc tttcgtgcca tatgttgcat actcagctac ccgaacatct ttccctgcca
    20821 ctgcaatcat ataatgactc gctggaagtg gttctctgag acaagctaat actgttgcat
    20881 aagttgtatg agcatggata attgcatcga tatcatcacg agtttgatat tgaatcaaat
    20941 gcatatacca ttcgctagat ggcaagcgtt ctccctctac aacatttcca ttaatatcca
    21001 tcactacaat atcggattct ttgatttcaa agaaatcaat acccgacggg gtaattgcca
    21061 tcaattgttt ttcacgatcg aaaacgctga gattcccacc tgttcctttc gtcaaatctg
    21121 tttctactag cttcttacca tatttaatta attcttgttt tacatctgac atccttgtcc
    21181 tcctcatatc aaaacactaa atatttttca attcaccaat tatcccccct tcctgcacaa
    21241 aagctaagaa gggggaggga ggcaaattta caaactctca atctttttaa ttcttttggg
    21301 agtaataact ctctaattgt agaaactcct caataacatg gtgagcctct tccatccctt
    21361 ttaattgtcc catagctatg agctgcacaa caatattccc cacagctgta gcctcagtca
    21421 aacctgtaag aacctcttta ccagttctat cagcaatcat ttggttaaag taactggctc
    21481 tagcacctcc tccaatcaca tatatcctct tataaacctt atgagttagt tcttctagta
    21541 actctatcgc tttcctatac gtttcagcta ggctttcata aacaatctta aatagttgtc
    21601 catctgtcca ctctctagtt tcatgatgat aagctagata ttctgtcaaa gtcttgtgca
    21661 tatcagattc tgttgcaaat tcagttgatt cagtatcaat cagaggaaga ttttcttttt
    21721 ctttctccac cattgtccta atatcatcaa aagaataggc tttccctctt cgttcaaatg
    21781 aacgtcttag ttcctctatg atccacaacc ctgtacaatt cttcagaaat gtaatcactc
    21841 catctttacc gacttcattt gtaaatccat aactgaagga ttcggtagta agaatcggtg
    21901 aagtaagttc cactccaacc aaagaccaag tacctgatga aataaataaa ctaccttctg
    21961 tcttaggtac tgagacaatc gcacttgctg tatcatgact acaaacattc acaacaggaa
    22021 tatcgcttaa accatactcc ttttttatcc ttccaaggac atttccctct gaaacaattt
    22081 caggaagtaa agttgaatcc aattcaaata gttttaagat attctgattc caattttgac
    22141 tcctaggatc aaataattga gttgttgaag caatgctttt ttctgtagca aacttacctg
    22201 tcaagagata attaaacaaa tctggcatta aaagaatctt attggtctta tagaaagagt
    22261 caggagattc ttgacgtgcc ttaaagagtt gaaacaaggt atttatctcc ataatctgat
    22321 ttcctgtctc tgaatacagt ttttctaatt cagtcatttc agatatttcc tttaacactc
    22381 cctttgttct ttcatcacga taatgaacag gttgtgataa cagcttacct tcattatcaa
    22441 tcagtccaaa atcaactccc catgtgtcaa taccgataga taaaatcttg taactagtat
    22501 tagccaagcg gatactttca agaattttag ctagtagaaa gtcaacatcc caagataaat
    22561 gcccttttac tctaataggt agattagaaa agcgatttat ttcttccatt actagtttat
    22621 tttcagaaag gtaaccaacg attgctcttc cagaagtcgc acctaaatct attgctaaaa
    22681 ccgcttccat ttttcttctc tcttcgtcct tgattaactt tattataatc cccacgtttt
    22741 attttttcaa tatgtgaacg cttacttgaa taatgttcaa atgttaaccc aatattcata
    22801 aaaataattc acattcctcc aatttgtgct ataatatagt tgaaatgata aattaggagg
    22861 agcttatgat aaaagatgaa cgtgtacttg aattgattga aatcatcaaa aagaaaaaaa
    22921 gaattgccgt aaaagagctg gcagaaatca ctttctccag cacaagtacc ttacgtcgtg
    22981 atttaatttt cttagaaaat caaggtctta tcaaaagaaa gcacggatac gtgaccctgt
    23041 cctctatgaa cacaattgaa ctttctcatc aaatacggga aggagaaagt actaggcaaa
    23101 aaagactaat cgctagtctc gctaaagact ttattcggtc tggtatgtgt atctatctag
    23161 attctagtac tactgtctac gaactttgtc cctatctttc tgaacttgat aatttgatta
    23221 tttttacaaa tggtttacat actgcacaaa ccctatctga aactgttaaa gatagctcca
    23281 aaatctttat cacatctggc gaggtcaaac atcaatcctg ttccgtggtc aactatgata
    23341 aggaaaattc tttattagat cattttaata tcgatttagc attttgttca gcaagaggta
    23401 ttgatgacca atatgtttat gaagcttctc tcagccaagc tatttcaaaa aagaatatta
    23461 ttgacaaagc ccatgaaacc atcttactga ttgatagttc taaattttac aagactggat
    23521 tttttaaaat taatccccta tccaaataca caacctttat ttctgacacc ttgccagacc
    23581 aaaaattatt agacgcagtc gaattatttg atggagaatg ggtttctgat attcaataaa
    23641 aatcaaatag gaagctagtc tcagcttgct cacagtacag atttgaaaac tgatgaagtc
    23701 aaggccccca tggacacggc aagacgaagc tgacatgatg tgaagagatt ttcgaagagt
    23761 atcgttctgt ctgctgactg atttacaaat attcaccaca tgacattatt ttcttagcaa
    23821 ccctaaaaac agaggctgga caaaaactca atttcaggag aaatggggca aatattccca
    23881 caataaaacg catagtatca agtttttgca cacctgatat tatgcgtttt tctgatttta
    23941 aagactttgt cgcctagacc ctatatttca agaattaagt gaccttgatg atctaaatgt
    24001 attgtggtat actatttttg tcatcggtta ccgattacgt tcctatgggt tcgtgagagg
    24061 aggtgaaact aatgagcctt atcatagagc tcgctcttac tattatagcg gatgttatag
    24121 ctggaattat cttgtatttc gtctgcagat ggctagatag taaggagtag accgactgac
    24181 tagcctataa acacccgtta aatcgctaag atacgtcaaa aaagccctta actacggcca
    24241 tagttagggg ctttggtgtt ctaatgaacc ttatcaatta actacatttt agcatataag
    24301 tcctaatatt tcaagcatta agcaatgttg atgatctaaa tttaatgtga tatactattt
    24361 ttgtcatcgg ttaccgatta cgttccttac ggttcgtgag aggaggtgaa actaatgagc
    24421 cttataccag agcttgctct tactattata gcagatgtta tagctggaat tatcttgtat
    24481 ttcgtctgca aatggctaga tggtaagaag tagaccgact gactagccta taaacacccg
    24541 ttaaatcgct aagatacgtc aaaaaagccc ttaactatgg cactagttag gggctttggt
    24601 gttctaatga accttataca ctaactacat tctagcatat aagcccagat atttcaagag
    24661 ttttatttat tttttcaggt tcccttagtt ctgaaaggtc tataatgaag ttagccatct
    24721 agtatcaaaa aaccgactag ctcttatgaa ctagtcgatt tctcatcaat gcgccaacat
    24781 ttcttgagcg atttcttggc cagataggtt atctgggtag taggttggcc agttgtccat
    24841 ttcttcaaag agggcttctt ggcttgtgcc tccaaagaag atatggaaat gttctgcctt
    24901 aactggggcg atattgtggt cactaaactg aacatacttg aattgtccag cgtcagcatc
    24961 tgtggcttca aagaggaaac gcacgccacg attgcctttc ttgtaagtca aaattttctt
    25021 accgacatac ttgtaagtat atttcttgct ttgtccacct tgaacaaatt ccatagtatt
    25081 atcagtaatg ttaatcttag tcacatctgt ctgatagcct tttgtatagt aagccttgta
    25141 ctcagcctgg gtcatcttac cagtcaactt agccttgtag tcaaagactt ggtcaaacgt
    25201 gccgtcttca aggaaaggat aaactgattg ccagttacct gcatagtcac tcaaggtgcg
    25261 gtccttgaca gctgcatcct cgaagtaacc attttggact gtcttggtat cctctgcctt
    25321 ttcaggctcg atcgctgggc cttcttggtc tgttgtttgt ttcaaagcct tgaggttttt
    25381 ctccatgata gagatgtaat tttctccagc cttggtgtcc tcttctgtca gactttctaa
    25441 aggattgagg acatcagttt tgacacctgc ttcttttgaa agtgtgttag caagggcttg
    25501 tgaggcattt tcttcaaaat agatataggc gattttattt ttcttgacat actctgtcaa
    25561 ttctgccaag cgagcagctg atggctctgc atctggagaa agtcctgaga ttgcgacttg
    25621 tttgagtcca tagtccaagg caagatagtt aaaggctgcg tgttgagtca caaagctctt
    25681 ttgttttgct tgagacaagc cttctgcgta agccttatcc aaggcttgca atttttcgat
    25741 ataggcagct gcattcttct caaaggtctc ttttttatca ggataatctg ctgacaagct
    25801 gtcgcggatg tgctctacta gtttaatggc acgaactggt gataaccaaa catgggggtc
    25861 aaactcatgg tgatgacctt cttctccatg gtcatggtct ccctcttctt cctcgccacc
    25921 tggcaagagc aacatatcgc ctgtcgcctt gatggttttc acttttttct tatccaaggt
    25981 atctagcaat ttaggtaccc atgtttccat gttttcattt tcataaacga aggtatctgc
    26041 atcttggatt ttggcaactg ccttggcaga tggttcgtat tcatgaggtt ctgtcccagc
    26101 accgattagg agttctacat tagccgtatc tcctgcgact tgcttggtaa attcatagac
    26161 agggtaaaag gttgtcacga tattgagttt accatctgcc tgtttttgat tggaacaagc
    26221 cactaaaaac aaggcacata gactggctag taataagcta atttttttca cgttcgtctc
    26281 ctatttgata aaacgtctta ctaaactgat tagtataaag acagttacaa aaataatggt
    26341 aatacttgca cttgcaggtg tttctgcata gtaggaaatg taaagtcctg ctaccattcc
    26401 caaaaagcca atcgcactgg caagcagcat aaccgattta aagtttttcc ccagacgcag
    26461 ggcaatacta gctggcaaga ccataatggt cgataccaga agagctcctg ctgcaggaat
    26521 cataagggca atagccaccc ctgtcaccat gttaaaaaga atggacatgg tacgaactgg
    26581 caagccatcc acaaaggccg tatcttcgtc aaaagttaag atatacatag gacgaagaaa
    26641 gagaaaggtc aaaatcaaaa caaccgccgc aatgacaaag agggaaatga cctgttcttc
    26701 actgatagtc acgatcgaac caaagagata ttggtccaaa ctcattgaac tcgagctttt
    26761 acccttgctc atgacaatca gagaaacagc caaacctgtt gacatgagga tagctgtccc
    26821 gatttccata aagctcttgt aaaccgtacg gagatactcc agaaagaccg ccgcaatcaa
    26881 gacaatggca atagtagaaa cagttggaga aatccccaaa accagaccaa aggctacacc
    26941 tgaaagtgag acgtggctaa gggtatcact catcaaactc tgacgacgca agatgaggaa
    27001 ggttcccaat accggtgaga aaagactcat agcaataacc gccaaaaagg cgcgttgtat
    27061 aaagtcataa gataataaac taagcatggc ccacctcctg cccattctca tgaacgttga
    27121 aacaacgcca tggcgagtct tggttacgga ctagatgaat attgcgatcc gcataatcct
    27181 taacttcttc agggtcatgg gtaatcatca aaacagcctt gccatgatga tgggcgctgt
    27241 ggtgcatgag ttcgtaaaat tcatttttac ttcctgcatc catccccgtt gtcggctcgt
    27301 ctaggataaa cacatcaggg tcagaagcaa acatacgcgc aatcaccgct cgctgctttt
    27361 gtcccccaga tagagacccc aagcgtttgt ctcgatgttc ccacatgcca actgagtcca
    27421 gactggcctt gatatgctcc tcatcatgag cattcaaacg acggaaccag ccttttctcg
    27481 gatagcgacc cgacttgaca aattcataga ccgtacttgg aaaaccagca ttaaaactgg
    27541 caatttgttg aggaagatag gctattctca atttcttacc ttgcgtattt gtctttgaaa
    27601 tagccacctt tccaatgcgt ggttgcagaa ttccaagact ggccttgatg agcgtcgtct
    27661 tagccgctcc attttcccca gtcaaggtaa caaattcccc actatcaaca ctataattga
    27721 tatgttcaag aacaggctcc ttatcataat agaaggacaa atcctctacc gtaatatatc
    27781 tcattatttg atttctccta ctaaagcagt caaaaaccgc tgaatcactt tttgttcatt
    27841 tggagtaaac tgagtcgcca cttgttcata ggttaaaagt gtatgctcat ggtgatggtg
    27901 gtgctcctca gcgattggac gagccaagtc agtcaactga taaaaaatca cacgcgcatc
    27961 tttagaatct ttagatgttt ccaacatccc ttccttgacc aaagacttaa tggccttggt
    28021 aactgccgcc tgactgacat tgagacgacg ggccaattct gaatttgtta aagattcctc
    28081 tgacaagagc ataaggatat gctcctgagt attggtcagg gccacctcgc tagtgcaatg
    28141 acctattagg atttcatgct gattttccgc ctgcaaaatc acctcattca aaaaagcatt
    28201 gatatccttt gctagctgtc tcatatctga ctcctttcct tttagacttc tcttttttaa
    28261 gagaaaaata ctattctttg acattttgtt taccagttaa ttatatcaca agcaaaaaaa
    28321 gagtcaagaa aaaacgtgaa aactagtttc attcttgaac tcttctatat tatattatct
    28381 attgaaattc tttgacatct ccatcataag tcgcccaatc tttgctgaaa aagcgctcat
    28441 tcagatggta agtcggagct ggtgtgggat tggataggaa aggatcaact gccttgtcaa
    28501 aagccaacca acccaaccaa ccaaggtgaa tggtgtcctt cataaagaaa ggctccccac
    28561 cgtccttaga aaaatctgct atattggtaa aaccttgact ttctaactgg tagcgaatct
    28621 tctgcaccgt ttgttggtac atatcctctc gtagaccagc atagtccatc cattttttat
    28681 taacaggtgg aatgataaaa atcgggttta ccttagattt agaaaactgt gttaaaacca
    28741 actgcaagtc attatactct ggcgacttga gataggtaaa gcttttctga gaatccttta
    28801 atttcttcaa atccttcttg atctgctcat tatagaaata attttccatt cccatctcat
    28861 tattggaagt atttttttca gcatctgctt tgacaacatc ttctattgct tgataagaaa
    28921 actggtctgg caagattttt aaatacttag ctacatgctt atcgtagtta acatagcctc
    28981 taaccgaaaa ctgaccaaaa aaggaggctt ggcgttcatt aaaacgagcc aataattcaa
    29041 tcatttcatt gtctgctgtc gacaattctt ctttacttgc caacttctga accaggtcct
    29101 tcatagctac gtttgggaac tgttgcagta agcgagtcgc tgcatattga ctagcctgat
    29161 ccccagattg atgtttcaga aaactagtca actggtctcc attaaaatac tgctggaagg
    29221 ctgctggatc atagccattt ttactgaacc actgaggtga gataacatac acaacttgtt
    29281 tattctccag ctgtggtaac atctgttgca ttccaaaata ttggttaagc gatgcagctc
    29341 ccccctgtcc taaaagataa ggacggtagg aacgattgta tttctcagct aataccgcag
    29401 gatgagcacc gtcaaaacga agccattcac tagagccaaa gaagggaaca aaacgcacat
    29461 ttggatcaga tagtgctctg actttttgac ttcgctcctt aaaactatcg atagtagtag
    29521 ccactgctga acgcttttca gctcctagat tatgatgcat ctcagtagga taaaagaaaa
    29581 tgagcagaaa aaccaacaaa ccagcgatca agaccggtcc gaagatcatc cataagcgtt
    29641 taagcatttt gtagctccac aataccagct atgattttat tagctgtatt ccagtcgtca
    29701 cgaccaaact ctgttacagg gacacgaatg tcaaaacggt tctcaatctc cacaatcaac
    29761 tcaaccgttc ccatactatc caagacacct gcatcaaaaa gatcttcatc catcatgtca
    29821 gaaacatctt ccataaacaa ctcatcaata atttcaataa cttctgattt gatatccata
    29881 ttttatttcc ttttattttt taaaccatag attattcaag aatccagaaa agattaagaa
    29941 tgacaacatg acaacatgga aagtgacaac catgccaagc aactgaatcc agcgattctc
    30001 aggtagggca gccttccctg cttttttccg ttccttattg agcgtttttt tcttgcgaac
    30061 ccaggcatca ttgatgacca agcctagtcc atgaaagagt ccataggcga tatagtacca
    30121 ggtcacacca tgccaaaatc ccataatcag catatttaca atgtaggcca tgcttgaggt
    30181 tacattacga tttttaaaga ctttctttct ggttaacacc atcaccattc gcataaagac
    30241 aaagtcacgg aaccagaagg acagactcat atgccagcga ttccaaaact cctttaaatc
    30301 ccttgataaa aagggcttgt taaagttgat agggctacgg attcccatca agtttgagat
    30361 ggccaaagca aacatagaat aacctgcaaa gtcaaagaag agctccagac caaaagtata
    30421 cataactgcc aaggcataga gattaaagaa gccacctgac tgcaaggcta aattcttcag
    30481 aggaggtagt aaggtctctc ctaaaacatg agctaggata aacttataca aaaagcccca
    30541 catgatatag cggacagatt catccagcat atccatcaac tcatctcgct caggaatagc
    30601 ctgataattt tcattaaatc gcttaaagcg atcgattgga ccactcgaga aagttggcat
    30661 gaagagaagg aaacggagga attcccagag ggtaaaatcc ttaatcactc catctctcag
    30721 ctcgatgata atcccaaccg aacgaaaggt caggtaagaa attcccaaga acccaagcaa
    30781 agactgcgtt ccattgatag ctggttgcac cttgacaaag ataatcggaa gtagggacag
    30841 aaaactaact aagtagaaga cccacttgcc atccttgctt tttcgataat gcttgtagaa
    30901 aagcaggagc aatatttccc agcaaaggta aatacccaag gcagctagtt gattggtctt
    30961 tccacccacc aacatggtga caataaagaa gagacttacc aacacttcat accaggcaaa
    31021 gcgtttcttg aaaaagaggc ctataaagat gggcaaggtt gcagcaatca cataaacaaa
    31081 atactgagga ttgccatatg gctctaaatg aggaagctgt tgaaaaaact ccatcatctc
    31141 ttattcacct cgttaatcaa tcctttgatg tcaatctttc catttggagt tagtggcaaa
    31201 ctgtctcggt aaaggaattt agatggcatc atgtaggaca tcatgatgtc tgtcaggtct
    31261 tccttgatgg ccttggtaat atcgatatct cgctcaaact gctcacgaac accgtctttt
    31321 aagatgacat aagccaatag attttgtacc ttgtggtcct tgttatagcg cggtactgcg
    31381 acagcagatt cgataaagcg agacttgttg aggttttgag agacatcttc taactcaatg
    31441 cggtaaccgt taaacttaat ctggaagtcc atgcgtccgc cgtagagaag caagccctca
    31501 tctgtcatgg ttcccacatc gcctgtgtga taggctggca gaccttcaaa ctcaaagaag
    31561 gcttctgctg ttttttcagg atttttcata taaccttttg aaacagctgg cccagaaaca
    31621 atgatttctc cctgctcacc atttggcagt ttatttcctt cctcgtcaat gataaaggtt
    31681 ggagaatcag ccttggtata gccgattggt aggcgtttga gagtcgctaa catctcgtct
    31741 gtcacggcaa ctgctgacag agctactgtc gcttctgttg ggccgtaagc attgatgata
    31801 cgggcatttg ggaaacgctc gcgcagtttt tgagctgttt tgaccgtcaa ttcttcacca
    31861 tcaaagtaga aatgcgtgat tccagacatt ttctcactgt tgaagtattc agacaacatg
    31921 gccatatctg caaaggatgg tgttgatgtc cagatagcga ttggcaatga aaagatagcc
    31981 gcaaagagtt gcttaaagtc ctgagtgatg actgaaggaa gagtgaaaag cgtaccacca
    32041 agtgccaagg tcggtgccca atacatgaca gacaagtcaa aagaataagg tggctgtgcc
    32101 agcatttgcg gacgactcgg tgtcgcaaat tccttatccg taatcatcca gtttgtaaag
    32161 ctgaggagat tatcatgtga aatctgcact cccttaggct taccagtcgt accagaagta
    32221 aagataatgt agtaattatc atctcccttg actggatgcg tgatttcata gttgttccct
    32281 tgggcaaagg cttcttgaac ctgagctaga tttatcattg gtgtagaaac ctgctccaag
    32341 ggaaaggctg aaatggcaat aatcaagctt ggctctgcta cttctaaaat agctgaaact
    32401 cgctccaagg ccgaatggct atcaattgga atgtaggcat gacctgactt agtcagcgct
    32461 acaaaggttg ccaacatttc atattcttgg ccaccaaaaa caaccacagg agacttctca
    32521 ggcaagccta gttggtcaat gactgcagcc aaactatccg aatcagcctt taaatcgcca
    32581 taagtgtgtt cctgccccaa aacattatag acaggatagc taggctgtgt ctgagcaaaa
    32641 tgctcaatgg tttcaatcat atctgctatt ggtttatttg acacaatagg gattctcctt
    32701 caagttaaaa ttcattatag ataaagcttc cttgaccctg accaagatag ctaaagaagt
    32761 aaagcagccc tagaaagata agaaaataca aggctgtccg accaagaaag aggtacaatt
    32821 cttttctctg tttcatcaag aaaaaccatt catttctgta atttttcgct aaaataagag
    32881 tgattcttac tagcttattt ttctaccatt gtaccacttt atatagtatc ttttcaattg
    32941 tttaccgtat gtttccaata gatttcagct tattttaagg attatacagt ttttctatgt
    33001 atattttcaa atagagtgat cctgcttcaa aactccattt caggagacaa tgaagtaaat
    33061 cttcccataa taaaacacac aatatcaagt tttttcaaca cctgatacta tgcgcttttc
    33121 tgatttttaa agacttttta accactctct catttaaaat aatctcgtct gatataaatt
    33181 aaaatagctt ctatcatcag acaaatggct gatagccaaa aactgatgct aataccaaaa
    33241 ctctcagtaa tatagctcat tagcaaaaca aatactgaaa atgctaatgt agaaatcact
    33301 tcaagaacgg aatagacatt aactaaatga ttttcctcta ctgtttcctg aagaaataca
    33361 ctttcaggaa cttcttttag ttgcgataac ataccaacta aagctgaaaa taataaaaac
    33421 atctgtgcgt ttggaaaata tagaatagtc agtgtcacta ttgccatagc tacaagagga
    33481 aaaagaatac tttcccattt agcagcaagg aacttttcag atagcctaaa agcaattaag
    33541 ccactaatta taataccaat agagtatgct gtattagaat atccccagta actttccgtt
    33601 ttatttaata actccgttac aaaaacaagt ataatggaag aaacccaaat cgtatttgaa
    33661 aaaatttcca ataaatttgc tgatacaaaa agtcttaatc taggatttct agcaactaac
    33721 ttccaacctt tgagcaaaat ttcaagatta gtttctgact ctaacacctc cacttcagcg
    33781 ttaggaagaa ataacatcag aaagctagaa atgatataca agactaaaat gataaacgtg
    33841 gtaggtaaca gaccaattgt tgcaaataag agtccaccta atccccaacc tatcaattga
    33901 acagcttcac cagtcattga taaggctgaa ttagccttac ccaaatcggt cgcatagcgt
    33961 ggcacaatag cataggaaac gggtgctgca aaaccatcta gtatggaaat tgcaacaaca
    34021 aatagatagg tcaccaaagg cgctacggat tgcattacgg taaacattcc taccagtatc
    34081 gccaataata tagtctttcc aaattgagat aaagataaaa ccctatttag cgctaacctt
    34141 ttagtaacca acggaactaa aagactcgca acaaaagagg atattcctat taagatagga
    34201 actagtgatg tggcaattac tgattttgaa ataatgtata tgttagcaat gattgttact
    34261 ctaaagaaaa tatctgctaa atttgcaaat aattgagaga ctaacaactt gacaaatgaa
    34321 ttagacatgt agcgctcccc ctttagttac aaactttgga attaaatttg atttttaata
    34381 ttttagcata aaatagcaga aaacaaaagt gaggtttttt acatgaaaaa acaaaaacta
    34441 ttgcctttat tattcctaat tttaggagga attatgatta tcgttgttgg ctagtactaa
    34501 gaagttagtt agttagtaga ataattacat cttcaatcga aaaagagact gggaaaaagt
    34561 cttaaaaatc agaaaaacgc tcaaatcctt tggcgctcta agcttttcta atgatagatt
    34621 ttagatagtc aaaaaaatat ctgaaaagtt cccagatcgt cgtctcagca tcaaaaatac
    34681 gtgaaatttg cataattaaa ataaatttca ggggagttaa tcgagtaggg gataatctct
    34741 agcccctctc acaccaccgt acatgccgtt cggcatacgg cggttcaact aacttttaac
    34801 gcatgtcgtt caaggtaata atccaaacac gaaaccagtc cacgtttttc aaggactggt
    34861 tttgatatag cacgtttaag taccgacttc tgagctacta attgataatg gtcgccccag
    34921 ccagatacct tatctgctat ccatttagga actcctaact taagcaatcc ccatagtcgt
    34981 ctcgatttct tcttccattg cttccagata atcactcgta ggcgagtacg caagcgctca
    35041 tctatgctag cgactatgcg cttcatattt cccagcgaga aatagtttat ccatcctcga
    35101 atagacaaat tcagttgctc aatacgtctt gttaagtcta tactccattt cctctgtgtt
    35161 agtttcttca atttaagctt aaatctccga acactatctt gatggggacg acttttccaa
    35221 ccatctgatg atttccagaa cccaaaacct aagtatttca gctctcttgg tctggtaatc
    35281 ttagccttgg tcatatttac tttcaaacct agtcgcttct caataaaacg actggctgaa
    35341 tacatcacac gcttagcggc tgcctcgctt ccgaccgtaa tcacacaatc atctgcgtag
    35401 cgcacaaatc gaagtcccct cttttctaat tccttgtcca attcattaag catgacattg
    35461 gataagagag gagataaatt tcctccctgt ggcgtgccaa ctagcgtttt atgacgctga
    35521 ccattaatga taacacctga atgaagatac ttacgaatca gggattccgt atctccgtct
    35581 tcgataatgt tatgtaccaa ggacatcaat ctatcttgag gaaccgtatc gaaaaatttc
    35641 tctaggtcta tatccactat ccactcatag ccgtcattta agtactctaa gaacttcatg
    35701 atggcttttt cacatgacct atttggtctg aagccataac tcgtatctga gaaatggggt
    35761 tcacaaatgg ggctaataac ttggacaatg gcctgttgaa tcattctatc cataactgtt
    35821 ggaattccta gttgacggat acctccgttt ggtttagtaa tctcaactct aagaactggt
    35881 tgaggcttat attttctctg ttttatcagt tccttagtca agcgccagtt ttgtctgaga
    35941 taattatcca tctcttcgat agtcattcca tcaatcccag ctgagccttt attggatttt
    36001 acttgattgt aggcttccag catattttcg cgtgataata tcttatctag caattttgac
    36061 atgtgcgtat tcctttcttg ttttggtgcc tgagggacat cttatattgg tgaaccttca
    36121 tctagtcatt acgtgtcaaa gtccagttct atcagaccac tcattttaca gacacaagtg
    36181 aagtaggatt acttcgatct gtcgttttct ctttctagcg acagacctca aacagtctct
    36241 ccccagactg tttgagtatt caccccttcg ctccacttcc attacggaag tttcctcact
    36301 actatgggct cggctgactt ctcatgattc gttgttacta cgctttcagc gctcatgaaa
    36361 cctcacggga taagtcgtac atctttcctc gtttatacaa gatatgagga cgttaaaagg
    36421 ttacagtgaa aataggaaat ctgacgcaga gtctttagac tctagaaaga tttatctttt
    36481 tcacacaaac cttagtccga attcaattac tctcgtgatt tacacatata ggttacgact
    36541 acctttttgg actttagagt ttgaagcctc cttatccgct atatacgcct tgctatcacg
    36601 ttcctgttcg tagagccacg atttcgctat ctcttcctct gacgattctt atttcctgcg
    36661 tcagacttaa aacggtctat ccccagaccg ttttaatccg ctacctcacg atagtcaggc
    36721 ttgggaatcg cttttgggtt caccggtagc aagtgcccac ggaggacttg cacctcagat
    36781 atacgacatg cccgtcgtac tacaaaaaaa cgacgattta aatcgtcgtt ttactaagat
    36841 aaatatgcat tttttttgaa aatacgtcta tttatttttt attgtttttt attgtagagc
    36901 agacccaagc gaatgaacat aggttgtaaa aagcaaatga aaaaactgcg aggataatag
    36961 cttctgtgtc taaataaccc atttcgagac ctcttttcaa caacaacaag cctgtagttt
    37021 cgataacgat caaacataaa aatatataaa aaattttcgc attaagcata ttgttaccgc
    37081 tttcttttta tttggtttta ttgtataata aaagttgaaa aaaatcaaaa atacaaagga
    37141 gtttccgtta tgtctaagat gtttaaatgc atgtgtttgc tagttatgtc tgttttctgt
    37201 atgtctagca tttccccgtc gcttgttgtt tttgctgatg atagcttatc ggcaaactct
    37261 aaagttgtat ctggtgaggc tcagtttgag aatggctcat cagtgcggtt cggagatacg
    37321 caagtaaata ttttaagcga tgaagttctt gaggttgtca atccagatgg aagtgtagac
    37381 actattgaac gacgtgctga cggcgtctat atcaatgggg cattttatat ggcttatcaa
    37441 aagaatgaaa tcgacctaaa tatatctttt agatcatacg atcctaatgt ttgaaattac
    37501 gtcaacacaa tacatgggaa taaacaagct aacacattcg ctaacttcat gactggtgct
    37561 ggaatcagtt atatgattgg taggataggt gctttattgg ggggtccatg gggtgcaata
    37621 attggtggag catattttgg tatacaagct tatcagtctt acttggattc acaaagccca
    37681 tatccatact acataacaag tacttatatc catgttgctc aaagaaaatg gaagtttatc
    37741 actgaatact atagaaactc aaactatact gggtatgtaa aaaccgtaac aacctacgtg
    37801 aatttctaaa atataaaccc tgcctagata taaaggcagg gtttatattt tagttaattg
    37861 ctcaagtaat ttgtaagcat aatacttgcg aaactctatt tgttcaagcg gttcaaaagc
    37921 tcttgttttt tatcctcaag ctcagctctc ctttgctcga tttcttcacg tttttgggcg
    37981 atttctgctt gcgcctcggg agtttccaaa gtgccttgtg acttgtgaaa ttctactagc
    38041 atatcaacga tttttgggtc taattcgttg acataatcag aatttgacta tttcggcacg
    38101 ttgcttgcag gtgcttgctt tttgccgcct tttttgggcg ttttggcttg ttgttcagct
    38161 ttctgactgt agttgacctc gtggaatttt cgtgcttgat atgatgcgtt ttattatgag
    38221 aagatttact tcattttttg ctgaaattgg gctcttgccc aagctctatc aacataattg
    38281 ttttctagat tagaaaagtg agaatacaag cacggccaag gctgctccga taacagggcc
    38341 tacaacagga atccaagcgt aagaccagtc tccgtctccc ttgtttggaa ttggcaagat
    38401 gctgtgcatg atacgaggtc caaggtcacg agctgggttc aaggcataac ctgttgtccc
    38461 acctagtgat agaccgatac cgacaatcaa agttcccact gcaaaggttc cgatacctgc
    38521 ctgaaaatcg taaagaccca aagcaaagat tgtcaacacc aaaacaaagg ttccaaggat
    38581 ttcgctaatc aagtttgata cagtatcctt gatggctggt ccagtactga aggttgccag
    38641 gatattgcct gcattttctt ctacctcata atgcggtttg aattgcaacc aaaccaaaat
    38701 ctgacccagc atggcccctg cgaactgggc taagatataa ggcaaaacgg aagcccaagg
    38761 caaaccacct tttaaggcca caccgatggt cacagctggg tttaaatgag ctggactgag
    38821 cttgccagat acaaagactg caaccgcaac tgcaatcccc caacccatag taatcacaat
    38881 ccaacctgag ctattgctct tggttttagg aagaaccaca cctgcaacaa caccatttcc
    38941 tagaagaatc aggattaaag tccctagaaa ttctccaaat aattcattca tcatctttct
    39001 gtctccatta aaaagaaggg acgggcgaca aggaatgctg ccctccacct cttttatttt
    39061 ttcttaattt tttaattctg ctaagtcgtt ttgagcaaga gctgctttta catcagcacg
    39121 gtaagttgct ttttcttctt ctgtccagtc atagaatcgt cccatttcat ccaaaactgg
    39181 ctcaacgatg ctatccaagc tatcacgcat aaagagcata tggttggtac gacgaagaag
    39241 gaagtcaact gggctaagag ccaactcgtt gcgcattgca tagtgaaggg acaaagtatc
    39301 tgccaagctg agtcctggcg cttgttccaa gctgtgagca agtgcaaaga ccttcggtgc
    39361 atttgaaccg taaagatttg ccagatagtg agcttccttg ctatccaaac cacgtgatac
    39421 tccaagttgc gcaaaggctt cgatttctga atccacattt gctgggttca attctccacc
    39481 tgaaacaggg taagttttag aattgatcaa tttaaagcta cggtcaaatt ctgctttgag
    39541 gatgtcaacc acgcgctcca tagctccttc agccatctta cggtagtctg tgattttacc
    39601 gccagcaaga gtcaaaagac cattgtcatc acggtccaag ctagacccac gagaaactgc
    39661 agatggatcc aaatatttct cagatgtgct actttcaagc ttgctgacag cagactcaac
    39721 atcttcacgt gttttttctt tggagagata agattcaaca gtcgcaatca agttgtcaaa
    39781 gctttcatca ctgatggtac cgttatttcc accattatag tcagaggcac tgttccctgc
    39841 aatcaatgga cgaagacctg cccagctgct ttcgatatca tcaatggtga tgttggattc
    39901 tggaaagcgg ttgttgacaa tgccaagtag ataatctaca tcttcttgag ttacttttgg
    39961 atgctccaaa tcacctgtgt agtctgtatc agttgtacca aagtaagtct tgttttcacg
    40021 tgggagaaca aagaccatac gaccgtcacc caaacctgtg tcaaagtaaa ctggctgtga
    40081 aaccttgatt ttgcttgaat ccactaccaa gtgaactccc ttagttgggc gcatttgtga
    40141 gaattgcgtt cccttattag acaaattacg tactttatca ctccaaggac ctgttgtatt
    40201 aataaccaga cgggccttga tttcaaatac ttggtctgtc aagagatcac gagctacaac
    40261 acctgtaatc ttgccacttt cgtcaaaaag gaagccttct gccttcacgt ggttggcaat
    40321 gagggcaccg tcttggttgg cacgtttgat gttttcaatc acgagacgcg catcgttgtt
    40381 acggaagtca agatacactc cacctcctac caagccttcc ttcttcaagt ttggctggcg
    40441 ttccaagact tgatccttgc tcaaaacctt gttcgcagtt ggtgtgttgc taacacctgc
    40501 caagaggtcg tacaagtcca tggctacttt aagacggaag aggctaaagg ttgctccatc
    40561 ttcatcgtaa actggtaaga gcattgggtc tggttttgga atgtgtggag cgatttgttg
    40621 aaccactgca cgttcagaaa ccgtatctga gaccacttcg acgtcgaatt gtttgaggta
    40681 acgaagtcct ccgtgaacca attttgttga acgactagat gttccttctg caaagtcttg
    40741 catttcaatc aaaccagtct caagaccgct agctgccgcc tgcaaggcta caccagctcc
    40801 tgtgattcct ccaccgataa tcaagaggtc cagggtgcgt tcctgcattt ttttaattga
    40861 caattcacgt gttttctttg aaaattccat atttacacac tttctaaata aatcgcttta
    40921 ttctgccagt attagtcgtc tacttccgca aagacttgag ttgctttcac agccttcttc
    40981 cagcccttgt agagttgttc cttgcgagat tcattcatag atggctcaaa gagttctcct
    41041 gtctcgttca agagtttcaa ctcgtccaag tctttccagt accctactga caaacctgct
    41101 aggaaggccg ctcctagagc tgttgtttcc aagtttttag cacgtgcaat gtcaatgcct
    41161 aaaatatccg cctggaattg catgaggaag ttgttcatgg ctgcaccacc atccaccttc
    41221 agtacttgaa tggcggtctg agtatccact tgcatggtgt cgatgatgtc acgcacttga
    41281 taagcaatag attgcaaagt cgccttgata aagtcttctt tgcttgttcc acgagtcaaa
    41341 ccaaagacgg aaccacgagc attttggttc cagtatggag cgcctagacc tgtaaaggct
    41401 ggaacgacat aaacttcatc gttgttgtga gaatcacgag cgtatttttc agattctggt
    41461 gaattttcaa ccatgcgaag accgtcacga agccactgaa tagcacttcc tgcgatgaag
    41521 atagaacctt ccaaggcata ataaacctta ccgttgattc cgtaaccaat ggttgtcaag
    41581 aggttgtttt cagacaactg catctcttcc ccagtattca tgatgatgaa agagcctgtt
    41641 ccataagtat tcttaaccat acctggctca aaagccaact gtccaaagag ggctgcttgt
    41701 tggtccccag ccatacctga gattggcacc tctccaccgt agaaatggaa tggagctgtc
    41761 ttgccgtaga tttcggagtt agaacgaact tctggaagta tagccttcgg aatgttaagg
    41821 atttccaaaa tctcatcatc ccatttgagt tctttaatgt tataaagcat ggtacgagct
    41881 gcatttgagt agtcagtcac gtgagccgca ccgtcagtca atttccaaac caaccaagta
    41941 tcgatagtac caaagagcaa ttcccctttt tctgctcgct cttgagcacc ttctacatga
    42001 tccaaaatcc aacgaacctt ggtagcagag aagtaagcat caataatcaa accagtcttt
    42061 tcatggaatt tttccacata accttggctt tttagttgct cagccaaagg tgctgtctgg
    42121 cgtgactgcc aaacgatagc attgtagata ggaagtcctg ttttcttatc ccagacaacc
    42181 gttgtttcac gttggttggt aatcccgatt gcctcgattt gatttggctt gacaccactt
    42241 tcgatgaaag cacccgcaat aactgactga acagagttcc aaatttcatt ggcattgtgc
    42301 tcaacccaac ctgcctgagg gaaaatctgg gtaaactctt tttgactcga gctaaccttt
    42361 tccccttttt tgttgaaaat gatggcacga gaacttgtag ttccctggtc aatggccatg
    42421 atgtattttt cttgtgacat gtactgtcct cctgataaag atcttgaggt gtttcctctt
    42481 tacacttact agtatacaaa ataaagcgct ttcttgttta tcaacttttt ttaattttta
    42541 aaaaaatgtg aggagattgt gtgaatttca caaaaaagac ctggattaac caagcctttt
    42601 aagtgaataa taactgacga atccctgcca aatcttccat atccaagtcg ttttttaaat
    42661 aatagactgg tgtctgttcc ttcttatgaa tcgggttatt ggtaaccagc aaatcataat
    42721 gccgactagg gtcataagct tcaatggtaa taaaacgatt gtattccaaa taccgtttca
    42781 aaatggctgc catccttgaa aagacaagaa aaccagatgt caaatccaga ccaatccgca
    42841 tatgctggcc accgttttca gccatatatt cgattaactg gagccattcc cagagaatct
    42901 tcttatctaa atctgtcccc tgttgaaaag caggtagagc atgaaaaatc tcctctgctg
    42961 tctctttaaa atcatgttcc atcagtaaat atggatgacg attctctaac tggtacttgt
    43021 agcgatcctg taaaatatag cccttataga gatagacttg agcacaaagc tgactgagtt
    43081 cataggtgac atggtcctct gtataatccc ccaatagttc ctccttcttc atttcttgaa
    43141 tcaattgcgt cagtaaatct gccaactgcc ctccaaaacc aagaatatac tccatagtat
    43201 gaagaggaag aatgcgatga gataggagaa aagagaagaa tatcatcatc tcaccatcct
    43261 caactcctag tggaatatgt tgcccagcaa aaaaggacgg aacctttctc agcaaacgaa
    43321 ggtagaaaat attgtcaaaa taccctcgca ttttctcttc tatgacttga aactgacaag
    43381 cattgacccg aagacgttgt tgactgatgt gagcccagag aaccaagtcc aatttctgcc
    43441 ccacagacaa acttgcaccg cagatttcct ctaaattggc aatctcctgt tttctctctg
    43501 gtttctgcat gtgaccttcc cattcctgac tcgaccagac ctttcggaaa agacagaaat
    43561 agaaatagcg aatctgatgc tctggacctc gccaacgtcc attttggatg gataaatcaa
    43621 attctgacaa aatctgattt aaaccagcca agtgacgacc aagcgtagcc tcgctaatca
    43681 ccaattcttg agccagctga tgggctaaaa actgttggtg gtagagaaga taaaccaaaa
    43741 tctggtattt aacagcactc tccaaaaaca agctccgaat atctctcccc ttggtagctg
    43801 caccgataga cagacgcaga ttttcatctt ctgagtgaat agccagctct aagccactat
    43861 ccaaagcctt gtcattgagc agggtgacat atttggttag ggttgctttt gaaaatcctg
    43921 tttcttccat tacagccttg acggtcgtct gagactcttg taatagaaag gaaaggattg
    43981 aaaattgacc acactcggct ttctccatca aatctcctaa atacatttgt tacccctttc
    44041 attttctacc ttaagcatag cataaatctt acaaatgcta aaataatctg tttctctttt
    44101 tattttcatg ctgatttcct ggtccattat cctgaaaatc agtaaacaca cggctccccc
    44161 tttgggcatt tttatgctaa aatagtagct atggataaaa ttattaaaac tatatcagaa
    44221 agcggagcct ttcgtgcttt tgtccttgat agcacggaaa ccgtccgcac tgctcaagaa
    44281 aaacatcaaa cccaagctag ctcaactgta gcgcttggtc gaactcttat cgccagccag
    44341 attctcgcag ccaatgaaaa aggaaatacc aaacttacag ttaaggtgtt gggctctagc
    44401 tctctaggtg ctattatcac cgtcgctgat accaagggga acgtcaaagg ctatgttcaa
    44461 aatcctggtg ttgacatcaa aaagactgcg actggtgaag tcctagtcgg accttttgtt
    44521 ggaaatggtc aattcctcgt tatcacagac tacggtgctg gaaatcctta caactctata
    44581 actcccctca tctctggaga aatcggtgaa gaccttgcct tttaccttac tgaaagccaa
    44641 caaacgcctt cagcggtcgg cctcaatgtc cttttggacg aggaagacaa ggtcaaggtt
    44701 gcaggtggtt tcctagttca agtcttgcca ggagccaaga aagaagagat tgctcgcttt
    44761 gaaaaacgca tccaagaaat gccagctatc tctactcttc tcgaaagcga cgaccatatc
    44821 gaagccctcc tcaaggctat ctacggggac gaagcctaca agcgtctttc tgaagaagaa
    44881 atccgtttcc aatgtgactg tagccatgaa cgctttatga acgctcttgc cagccttcca
    44941 agctcagact tacaggaaat gaaagaggaa gaccacgggg cagaaatcac ttgtcaattc
    45001 tgccaaacta cttacaactt tgatgaaaag gacctggagg aactcattcg tgacaaatct
    45061 taatacacct tttatgattg gcaatgttga gattcccaat cgtaccgttt tagcgcctat
    45121 ggctggcgtg accaactcag cctttcgtac catcgcaaaa gagctcggag ctggactcgt
    45181 tgtaatggaa atggtctctg acaagggaat ccaatacaac aacgaaaaaa ccctgcacat
    45241 gcttcatatc gatgagggcg aaaaccctgt ctctatccaa ctttttggta gcgatgaaga
    45301 cagcctagca cgcgcagcag aattcatcca agaaaacacc aagaccgata tcgtcgatat
    45361 caacatgggc tgccctgtca acaaaatcgt gaagaacgaa gctggtgcta tgtggctcaa
    45421 ggatcctgac aagatctact ctatcatcaa caaggtccag tctgtccttg atatcccact
    45481 tactgtcaaa atgcgtaccg gctgggcgga cccatctctg gcagtagaaa atgccctcgc
    45541 tgctgaagct gcaggtgttt ctgccctcgc catgcatggc cgtacccgtg aacaaatgta
    45601 tactggccac gcagaccttg agacccttta caaggttgcc caagctctaa ccaagattcc
    45661 attcatcgcc aacggtgata tccgtactgt ccaagaagcc aagcaacgca tcgaagaagt
    45721 tggtgctgac gcagtcatga ttggccgagc tgccatggga aatccttacc tcttcaacca
    45781 aatcaaccat tactttgaaa caggagaaat cctacctgat ttgacctttg aagacaagat
    45841 gaagatcgcc tacgaacact tgaaacgatt gattaacctc aaaggagaaa acgtcgcagt
    45901 tcgtgaattc cgcggcctcg ctcctcacta tctccgtgga acatctggcg ctgccaaact
    45961 ccgtggagcc atttcgcaag ctagcaccct ggcagagatt gaagccctct tgcaattgga
    46021 gaaggcttaa tagtttaaaa cccgtaactc tcttaaagag tctcttgaat gccgccattc
    46081 tttcctcatc aaaaaaactc cgtagtctct agcgctataa atccggctag agattacaga
    46141 gttatttttt aatctaaact tcctacaagg gtatattatc tactgaaagg atatggtatt
    46201 tgtagggaat actttaaaga gttcttacag gaagtcagta ttaactagtt atattaagtt
    46261 tagtttaccc attcaccatt ggcattgact ctatagctat ctacagttgt gttgactgca
    46321 agggcacctg agccattgac atagtaccat ttatctgata ctttgaacca ttggcttgct
    46381 ttcatagcac ctgatgcttc aagatagtac caggtatctc catctttcac ccaatctgtt
    46441 gccattgaac cgttagcgtt taggtagtac catgagccat tgttttggag ccatcctgtt
    46501 accatagcac cattgctgtt taggtagtac catgaaccat tgtatt
//
LOCUS       DAVLXH010000011        43173 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00028199
            SAMN33607166-rid17955573.denovo.011, whole genome shotgun sequence.
ACCESSION   DAVLXH010000011 DAVLXH010000000
VERSION     DAVLXH010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607166
            Sequence Read Archive: SRR23725544
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 43173)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 43173)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721421.1
            Genome Coverage       :: 115x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:42:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,210
            CDSs (total)                      :: 2,161
            Genes (coding)                    :: 2,023
            CDSs (with protein)               :: 2,023
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 73 of 138
            Pseudo Genes (incomplete)         :: 60 of 138
            Pseudo Genes (internal stop)      :: 40 of 138
            Pseudo Genes (multiple problems)  :: 31 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43173
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607166-rid17955573.denovo.011"
                     /strain="AUSMDU00028199"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1349"
     gene            <1..731
                     /locus_tag="VYO11_000688"
     CDS             <1..731
                     /locus_tag="VYO11_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013851451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1595286.1"
                     /translation="SIGDVYEQEWIYEIEKEGEKRFAEAIPPGFNDENKDGIRKYNGI
                     SYHQKYGDLIIWKDILKKATEQPRGDKVIFITNDGESNKKSDLIYKTSNMKVGPSIFL
                     MNELYMCSRKKLYILNNTTLVNMITELSEDEIDRIEAQEEKKYVVTFPKWILDKAEKD
                     VRARNESNNSSVVYYIDSENRLASIDIDEVEPLELISLLENPDVKKMLKEEILKKMLD
                     SYYSKLPRHIIKDIINSYQEKNIQ"
     gene            complement(1286..1687)
                     /locus_tag="VYO11_000689"
     CDS             complement(1286..1687)
                     /locus_tag="VYO11_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEV1595287.1"
                     /translation="MLFFSISNDLLQLLTSWKEQQRYELAKFGILSNPEQFVFTYIDT
                     KGNINKPLHADYLNNKMKSIRKRHKELTHATPHKLRHTGATLAKKAGMSLEAISKALT
                     HSDTGTTQIYVNTSNVVPMTVGEFALKSLKQ"
     gene            complement(2063..3271)
                     /locus_tag="VYO11_000690"
     CDS             complement(2063..3271)
                     /locus_tag="VYO11_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEV1595288.1"
                     /translation="MNYIKRPHYLDFLRRHRDRQIIKVVSGVRRAGKSVLFQLYKEEL
                     IATGVDEDQIISINFEDLSYYDLRHFQTLFAYIKEQLIGEKTYYIFLDEIQHVEKFEL
                     VADSLFILPNVDLYLTGSNAYFMSSQLATNLTGRYVEIEVLPLSFEEYLSGQSLTENL
                     NTTEIFNNYLFSAFPYLLQTSSYAEKIDYLRGIYNSILLNDIVTRLGNPNPTIIERIV
                     RTLLSSTGSLISTNKIRNTLVSQNVSISHNTLENYLTTLTDSLLFYSVPRFDVKGRAL
                     LQRLEKYYPVDLGLRHLLLPDHKEDIGHILENMVYLELRRRYSQVYVGNLDKYEVDFV
                     VVTDLGHYAYYQVSETTLAPETLERELRPLDAIKDQFPKYLLTMDTIQPTANYNGIEK
                     KNIIDWLLEK"
     gene            3676..3852
                     /locus_tag="VYO11_000691"
     CDS             3676..3852
                     /locus_tag="VYO11_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1595289.1"
                     /translation="MSLDIDKEKMTIMGIAFENRSVFKSVWYALSTNMIEGWRPTVSD
                     VEKLRDEALALGMT"
     gene            4253..6466
                     /locus_tag="VYO11_000692"
     CDS             4253..6466
                     /locus_tag="VYO11_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000688702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 31 protein"
                     /protein_id="HEV1595290.1"
                     /translation="MKIFKGEFYRISVLTDKLVRLEYSRTGNFEDRTTQLIYNRDFGQ
                     ISLDYIETSNVLDIMTDYFHLHFNKGEFNAENLFIELKGNFAVYGSRWYFGESIETLK
                     GTARTLDKADGAISLEDGIISRNGIALLDDSQGFIWDEQSGYIERENQIDLYFFAYGH
                     DYRGAIRDFYHLTGSTPLLPRYALGNWWSRYWPYTSDEYLDLIDRFETEKIPLSIGVL
                     DMDWHITDIPARFGSGWTGYSWNRNLIPNPEQLLQQLHDRKLKLSLNVHPADGIRAYE
                     EAYPQIAKRLGLNVELEEPAIFDFFNPSFREAYFKDVHYELEKQGVDFWWIDWQQGTQ
                     GMLDPLWLLNHYHYQDSCKNAEGGLILSRYAGPGSHRYPVGFSGDTIISWNSLRFQPY
                     FTATASNIGYSWWSHDIGGHMLGDYDEELQTRWLQFGVFSPITRLHSSRSPFNSKEPW
                     FFSETTSKIMKKYLRLRHQMIPYLYTMNVKTHEEGAPLISPIYYFYPENDESYNVPNQ
                     YFFGTELMVAPIVEKMDLTFQSAKVDVWFPEGEWYDFFSEKKYTGGVKLSVYRDISTT
                     PVFAKSGAIIPLVGSEIGMGVDLPEVVDWYVFPGKQHSFEMLEDQNGQRYKTRLSIDW
                     EMGMVELALQGDSSIVPSNRKHRIHFKGTNVSIIELPNKNDTAKFEWKDNKRTSLNDE
                     VFRLLKTASLPYELKDRLLNQFINAKNSHDLMNILHHQDKELRGRLLEMIFTSQN"
     gene            complement(6688..7164)
                     /locus_tag="VYO11_000693"
     CDS             complement(6688..7164)
                     /locus_tag="VYO11_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HEV1595291.1"
                     /translation="MTSLYDFSVLNQNNQATPLDSYRGKVLLIVNTATGCGLTPQYQG
                     LQELYERYQDQGFEILDFPCNQFMGQAPGSAEEINAFCSLHFQTTFPRFAKIKVNGKE
                     ADPLYVWLQDQKSGPLGKRVEWNFAKFLIGRDGQVFERFSSKTDPKQIEEAIQTLL"
     gene            7387..10587
                     /locus_tag="VYO11_000694"
     CDS             7387..10587
                     /locus_tag="VYO11_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored hyaluronate lyase"
                     /protein_id="HEV1595292.1"
                     /translation="MQTKTKKLIVSLSSLVLSGFLLNHYMTIGAEETTTNTIQQSQKE
                     VQYQQRDTKNLVENGDFGQTEDGSSPWTGSKAQGWSAWVDQKNSAAASTRVIEAKDGA
                     ITISSHEKLRAALHRMVPIEAKKKYKLRFKIKTDNKIGIAKVRIIEESGKDKRLWNSA
                     TTSGTKDWQTIEADYSPTLDVDKIKLELFYETGTGTVSFKDIELVEVADQLSEDSQTD
                     KQLEEKIDLPIGKKHVFSLADYTYKVENPDVASVKNGILEPLKEGTTNVIVSKDGKEV
                     KKIPLKILASVKDAYTDRLDDWNGIIAGNQYYDSKNEQMAKLNQELEGKVADSLSSIS
                     SQADRTYLWEKFSNYKTSANLTATYRKLEEMAKQVTNPSSRYYQDETVVRTVRDSMEW
                     LHKHVYNSEKSIVGNWWDYEIGTPRAINNTLSLMKEYFSDEEIKKYTDVIEKFVPDPE
                     HFRKTTDNPFKALGGNLVDMGRVKVIAGLLRKDDQEISSTIRSIEQVFKLVDQGEGFY
                     QDGSYIDHTNVAYTGAYGNVLIDGLSQLLPVIQKTKSPIDKDKMQTMYHWIDKSFAPL
                     LVNGELMDMSRGRSISRANSEGHVAAVEVLRGIHRIADMSEGETKQRLQSLVKTIVQS
                     DSYYDVFKNLKTYKDISLMQSLLSDAGVASVPRPSYLSAFNKMDKTAMYNAEKGFGFG
                     LSLFSSRTLNYEHMNKENKRGWYTSDGMFYLYNGDLSHYSDGYWPTVNPYKMPGTTET
                     DAKRADSDTGKVLPSAFVGTSKLDDANATATMDFTNWNQTLTAHKSWFMLKDKIAFLG
                     SNIQNTSTDTAATTIDQRKLESSNPYKVYVNDKEASLTEQEKDYPETQSVFLESSDSK
                     KNIGYFFFKKSSISMSKALQKGAWKGINEGQSDKEVENEFLTISQAHKQNGDSYGYML
                     IPNVDRATFNQMIKELESSLIENNETLQSVYDAKQGVWGIVKYDDSVSTISNQFQVLK
                     RGVYTIRKEGDEYKIAYYNPETQESAPDQEVFKKLEQAAQPQVQNSKEKEKSEEEKNH
                     SDQKNLPQTGEGQSILASLGFLLLGAFYLFRRGKNN"
     gene            10940..11325
                     /gene="tnpA"
                     /locus_tag="VYO11_000695"
                     /pseudo
     CDS             10940..11325
                     /gene="tnpA"
                     /locus_tag="VYO11_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005816675.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            complement(11704..12333)
                     /locus_tag="VYO11_000696"
     CDS             complement(11704..12333)
                     /locus_tag="VYO11_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HEV1595293.1"
                     /translation="MTKSDTIIELKKQKIVAVIRGNTKEEGLQASIACIKGGIKAIEI
                     AYTNQYAGQIIKELVDLYQDDQSVCIGAGTVLDAVTARDAILAGANYVVSPSFHAETA
                     KMCNLYSTPYIPGCITLTEITTALEAGSEIIKLFPGSTLSPAYISAVKAPIPQVSVMV
                     TGGVGLNNIPQWFAAGADAVGIGGELNKLASQGNFDRISEIAQQYITLR"
     gene            complement(12343..13344)
                     /locus_tag="VYO11_000697"
     CDS             complement(12343..13344)
                     /locus_tag="VYO11_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HEV1595294.1"
                     /translation="MTKILLFGEPLIRISPLDATSIGDHVASSTYFGGSEINIACNLQ
                     ALGISTKVFTALPANEIGDRFLTFLKQHQIDTSSICRLGDRIGLYYLENGFGCRQSEV
                     FYDRKHTSISQIRPNMLDMDSLFQGISHFHFSGITIAIGQEVRAILLLLLEEAKRRGI
                     VVSMDLNLRTKMISALEAKYEFSKFARFTDYCFGIDPLMIDDQNLEMFPRDSASLEEV
                     ENRMRLLKETYGFKAIFHTLRSSDEQDKNVYQAYALEERFEESVQLKTAVYQRIGSGD
                     AFISGALYQLLHHSSLKTTIDFAVASATLKCTLPGDHLSTSATSIENLLANAQDIIR"
     gene            complement(13375..14016)
                     /locus_tag="VYO11_000698"
     CDS             complement(13375..14016)
                     /locus_tag="VYO11_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RpiB/LacA/LacB family sugar-phosphate isomerase"
                     /protein_id="HEV1595295.1"
                     /translation="MKIALINENSQASKNHIIYDSLKEATDKKGYQLFNYGMRGEEGE
                     SQLTYVQNGLMAAILLNTKAVDFVVTGCGTGVGAMLALNSFPGIVCGLAVDPTDAYLY
                     SQINGGNALSIPYAKGFGWGAELTLKLMFERLFAEEMGGGYPRERVIPEQRNARILNE
                     VKQITHNDLMTILKTIDQDFLKDTISGKYFQEYFFENCQDDEVAAYLKEVLAK"
     gene            complement(14035..14850)
                     /locus_tag="VYO11_000699"
     CDS             complement(14035..14850)
                     /locus_tag="VYO11_000699"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HEV1595296.1"
                     /translation="MTNTSFSIEQFSLKGKIALITGASYGIGFAIAKSYAEAGATIVF
                     NDINQDLVNKGIEAYREVGIQAHGYVYDVTDEDGIQAMVKQIEQEVGVIDILVNNAGI
                     IRRVPMCEMSAADFRKVIDIDLNAPFIVSKAVIPSMIKKGHGKIINICSMMSELGRET
                     VSAYAAAKGGLKMLTRNIASEYGGANIQCNGIGPGYIATPQTAPLRELQEDGSRHPFD
                     QFIIAKTPAARWGNPEDLMGPAVFLASDASNFVNGHILYVDGGILAYIGKQPE"
     gene            15122..15550
                     /locus_tag="VYO11_000700"
     CDS             15122..15550
                     /locus_tag="VYO11_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV1595297.1"
                     /translation="MKIVLVGHGHFATGIYSSLQLIAGNQENVEAIDFVEGMSADELK
                     QKILLAISNEEEVLILSDLLGGSPFKVSSTIMGENPVKTMNVLSGLNLAMLMEAVFAR
                     MAHSFDEVVNKSVVAAQGGVVNGKELFSTDAEEEDFELGI"
     gene            15562..16752
                     /locus_tag="VYO11_000701"
     CDS             15562..16752
                     /locus_tag="VYO11_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003074342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="unsaturated chondroitin disaccharide hydrolase"
                     /protein_id="HEV1595298.1"
                     /translation="MIKKVTIEKIKSPERFLEVPLLTKEEVGQAIDKVIRQLELNLDY
                     FKEDFPTPATFDNVYPIMDNTEWTNGFWTGELWLAYEYSQQDAFKNIAHKNVLSFLDR
                     VNKRVELDHHDLGFLYTPSCMAEYKINGDGEAREATLKAADKLIERYQEKGGFIQAWG
                     DLGKKEHYRLIIDCLLNIQLLFFAYQETGDQKYYDIAESHFYASANNVIRDDASSFHT
                     FYFDPETGQPFKGVTRQGYSDDSCWARGQSWGVYGIPLTYRHLKDESCFDLFKGVTNY
                     FLNRLPKDHVSYWDLIFNDGSDQSRDSSATAIAVCGIHEMLKHLPEVDADKDIYKHAM
                     HAMLRSLIEHYANDQFTPGGTSLLHGVYSWHSGKGVDEGNIWGDYYYLEALIRFYKDW
                     NLYW"
     gene            16763..17254
                     /locus_tag="VYO11_000702"
     CDS             16763..17254
                     /locus_tag="VYO11_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000178618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HEV1595299.1"
                     /translation="MTMPNIIMTRIDERLIHGQGQLWVKYLGCNTVIVANDEVSTDKM
                     QQTLMKTVVPDSVAMRFFPLQKVIDIIHKANPAQTIFIVVKDVKDALTLVEGGVPIKE
                     INIGNIHNATGKEQVTRSIFLGEEDKAALKELSQTHQVTFNTKTTPTGNDGAVQVNIM
                     DYI"
     gene            17269..18048
                     /locus_tag="VYO11_000703"
     CDS             17269..18048
                     /locus_tag="VYO11_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEV1595300.1"
                     /translation="MSINVFQAILIGLWTAFCFSGMLLGIYTNRCIVLSFGVGIILGD
                     LPTALAMGAIGELAYMGFGVGAGGTVPPNPIGPGIFGTLMAITSAGKVSPEAALALST
                     PIAVAIQFLQTFAYTVRAGAPETAMKHLKNHNLKKFKFTLNATIWLFAFIGFTLGCLG
                     ALSMDTLLKLVDYIPPVLLTGLTVAGKMLPAIGFAMILSVMAKKELIPFVLLGYVCAA
                     YLNIPTIGIAIVGTIFALIEFYNKPKTADHVVEEEAHDDWI"
     gene            18035..18853
                     /locus_tag="VYO11_000704"
     CDS             18035..18853
                     /locus_tag="VYO11_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEV1595301.1"
                     /translation="MTGSNKLTKRDYLKTSLRAFFCQNGFNYSNYQGLGYANVMYPAL
                     KKHYGEDQEGFYQALEENCEFYNTNPHFLPFITSLHLVMLENGRPAKETRSIKMALMG
                     PLAGIGDSLSQFCLAPLFSTIAASFAQEGLVVGPILFFLAMNTILTAIKLSTGLYGYK
                     LGTTVIDKLSEQMATISRIANIIGVTVIAGLAATSVKIMVPITFAAGEVKADAKQSIV
                     SIQGMLDKVAPALLPALFTLLVYYLIKEKKWTTYKLVILTVIIGIIGSWLKIIA"
     gene            18853..19146
                     /locus_tag="VYO11_000705"
     CDS             18853..19146
                     /locus_tag="VYO11_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000381741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HEV1595302.1"
                     /translation="MDTTLFYGIVIVLAVSPLLLSSFHSIRQQKLLRKQMEQRQEYLA
                     SLTSGDEVLLLSGIHGKIISIQDDLVSLQIAKGVVIYVEKESVMGKTKELLFK"
     gene            19168..21069
                     /locus_tag="VYO11_000706"
     CDS             19168..21069
                     /locus_tag="VYO11_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alginate lyase family protein"
                     /protein_id="HEV1595303.1"
                     /translation="MKEERRQFFERVDGNQCRDYILSHCSKDYEKVKRSLERLMNNRF
                     MFDSPWDMEPCSKIYQIQPMVWDQVFEDDPEWAYMLNRQEYLLQFMIGYVVEGDKSYI
                     QKCKFFLFDWIEQVREFSPQSLMTRTLDTGIRSFTWLKLLLLLLKFDLLEEKELEKIL
                     VSLEKQIDFMKSYYRAKYTLSNWGILQTIPILAIYHFFSDKMDLEEAYHFASEELKQQ
                     IETQILGDGSQFEQSILYHVEVYKALLDLCLLLPDLQDSYQELLEKMATYIQMMTGLD
                     GRTLAFGDSDSTETTEMLSLSAVVLNKEDLLNGLDVKVDLLSLLFLGREKVKRLQEFE
                     RRAWQPKSMIFEDSGHVCIKDEHRYLFFKNGPLGSAHSHSDENSFCLQYQGQPIFIDA
                     GRYSYREIYERYLLKSAWSHSTCIVDGKAPERITGSWEYEYYPHSLFCHHKEREGVHY
                     IEGAYWSAEPDLPYLHRRKILMLVEDVWLLVDDIRCQGQHEVLTQFILDKDVTYQDGK
                     INQLRLWSEVDFDLEDTIISPKYNELERSSKLTKRQFFENQMLDYTIIAHESFEIIRH
                     SVYQTDDREVENALAFEVKNDETDKLILLLSEDICVGEKLCLVDGTKMRGKCLVYDKI
                     NERMIRLQC"
     gene            21129..22130
                     /locus_tag="VYO11_000707"
     CDS             21129..22130
                     /locus_tag="VYO11_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV1595304.1"
                     /translation="MEKKLTIKDIAEMAQTSKTTVSFYLNGKYEKMSQETREKIEKVI
                     HETNYKPSIVARSLNSKRTKLIGVLIGDITNSFSNQIVKGIEDIASQNGYQVMIGNSN
                     YSQESEDRYIESMLLLGVDGFIIQPTSNFRKYSRIIDEKKKKMVFFDSQLYEHRTSWV
                     KTNNYDAVYDMTQSCIEKGYEHFLLITADTSRLSTRIERASGFVDALTDANMRHASLT
                     IEDKHTNLEQIKEFLQKEIDPDEKTLVFIPNCWALPLVFTVIKELNYNLPQVGLIGFD
                     NTEWTCFSSPSVSTLVQPSFEEGQQATKILIDQIEGRNQEERQQVLDCSVNWKESTF"
     gene            complement(22240..22575)
                     /locus_tag="VYO11_000708"
     CDS             complement(22240..22575)
                     /locus_tag="VYO11_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000838135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1595305.1"
                     /translation="MKSLARLLIIHVFISIFLFFALISGAVSHTVLLLLLLFLPALNK
                     GLEKIQSKRIPVLNAALFFLLISFPQLLTNPVQWKFSIFLVVTIISSLAYFYNFYQVV
                     KEVDQKQLI"
     gene            complement(22586..22828)
                     /locus_tag="VYO11_000709"
     CDS             complement(22586..22828)
                     /locus_tag="VYO11_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1595306.1"
                     /translation="MKKEKRQLRYPGLKAGSIYGTVIFFIIPLIDTLTSENPNFISSL
                     LNTKHIFKTMLGAFFFGVMIHIVDSLRIARAKKDQD"
     gene            complement(22844..23038)
                     /locus_tag="VYO11_000710"
     CDS             complement(22844..23038)
                     /locus_tag="VYO11_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001082472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1595307.1"
                     /translation="MNRVKEFRKELGISQLELAKDIGVSRQTINMIENDKYNPTLELC
                     LNLARSLQTDLNSLFWKEDF"
     gene            23204..24154
                     /gene="rsmH"
                     /locus_tag="VYO11_000711"
     CDS             23204..24154
                     /gene="rsmH"
                     /locus_tag="VYO11_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HEV1595308.1"
                     /translation="MTKEFHHVTVLLHETIDMLDVKPDGIYVDATLGGAGHSEYLLSK
                     LSEKGHLYAFDQDQNAIDNAQKRLAPYIEKGMVTFIKDNFRHLQARLREAGVQEIDGI
                     CYDLGVSSPQLDQRERGFSYKKDAPLDMRMNQDASLTAYEVVNNYDYHDLVRIFFKYG
                     EDKFSKQIARKIEQAREVKPIETTTELAEIIKLVKPAKELKKKGHPAKQIFQAIRIEV
                     NDELGAADESIQQAMDMLALDGRISVITFHSLEDRLTKQLFKEASTVEVPKGLPFIPD
                     DLKPKMELVSRKPILPSAEELEANNRSHSAKLRVARKIHK"
     gene            24166..24483
                     /gene="ftsL"
                     /locus_tag="VYO11_000712"
     CDS             24166..24483
                     /gene="ftsL"
                     /locus_tag="VYO11_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HEV1595309.1"
                     /translation="MAERMEKTGQILQMQLKRFSRVEKAFYFSIAVTTLIVAISIIFM
                     QTKLLQVQNDLTKINAQIEEKKTELDDAKQEVNELLRAERLKEIANSHDLQLNNENIR
                     IAE"
     gene            24487..26739
                     /locus_tag="VYO11_000713"
     CDS             24487..26739
                     /locus_tag="VYO11_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PASTA domain-containing protein"
                     /protein_id="HEV1595310.1"
                     /translation="MKWTKRVIRYATKNRKSPAENRRRVGKSLSLLSVFVFAVFLVNF
                     AVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDE
                     NYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQLSQPNLKQVSFGSKGNGITY
                     ANMMTIKKELETAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHENEDGSKSLLGTSG
                     MESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQQTVDGKDVYTTISSPLQSFMETQ
                     MDAFQEKVKGKYTTATLVSAKTGEILATTQRPTFDADTKEGITEDFVWRDILYQSNYE
                     PGSPMKVMMLAAAIDNNTFPGGEVFNSSELKIADVTIRDWDVNEGLTGGRMMTFSQGF
                     AHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLPADNIVNIAQSSF
                     GQGISATQTQMIRAFTAIANDGVMLEPKFISAIYDPNDQTARKSQKEIVGNPVSKDAA
                     SQTRTHMVLVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAQIADEKNGGYLVGTT
                     NYIFSAVSMNPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMKESLNLQSPA
                     KNLDKVTTESSYAMPSIKDISPGELAEALRRNIVQPIVVGTGTKIKETSVEEGTNLAP
                     NQQVLLLSDKVEEIPDMYGWKKETAETFAKWLDIELEFEGSGSVVQKQDVRTNTAIKN
                     IKKIKLTLGD"
     gene            26741..27721
                     /locus_tag="VYO11_000714"
     CDS             26741..27721
                     /locus_tag="VYO11_000714"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000470804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HEV1595311.1"
                     /translation="MFISISAGIVTFLLTLVGIPAFIQFYRKAQITGQQMHEDVKQHQ
                     AKAGTPTMGGLVFLIASVLVAFFFALFSNQLSNNVGMILFILVLYGLIGFLDDFLKVF
                     RKINEGLNPKQKLALQLLGGVIFYLFYERGGDMLSVFGYQVHLGIFYIVFALFWLVGF
                     SNAVNLTDGIDGLASISVVISLSAYGVIAYVQGQMDILLVILAMIGGLLGFFVFNHKP
                     AKVFMGDVGSLALGGMLAAISMALHQEWTLLIIGIVYVFETTSVMMQVSYFKMTGGKR
                     IFRMTPVHHHFELGGLSGKGNPWSEWKVDFFFWGVGLLASLLTLAILYLM"
     gene            28330..30435
                     /locus_tag="VYO11_000715"
     CDS             28330..30435
                     /locus_tag="VYO11_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001063457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEV1595312.1"
                     /translation="MNNNFNNFNNMDDLFNQLMGGMRGYSSENRRYLINGREVTPEEF
                     AHYRATGQLPGNAETDVQMPQQASGMKQDGVLAKLGRNLTAEAREGKLDPVIGRNKEI
                     QETSEILSRRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGL
                     EAGTQYRGSFEENVQNLVNEVKEAGNIILFFDEIHQILGAGSTGGDSGSKGLADILKP
                     ALSRGELTVIGATTQDEYRNTILKNAALARRFNEVKVNAPSAENTFKILQGIRDLYQQ
                     HHNVILPDEVLKAAVDYSVQYIPQRSLPDKAIDLVDVTAAHLAAQHPVTDVHAVEREI
                     ETEKDKQEKAVEAEDFEAALNYKTRIAELEKKIENHTEDMKVTASVNDVAESVERMTG
                     IPVSQMGASDIERLKDMAHRLQDKVIGQDKAVEAVARAIRRNRAGFDEGNRPIGSFLF
                     VGSTGVGKTELAKQLALDMFGTQDAIIRLDMSEYSDRTTVSKLIGTTAGYVGYDDNSN
                     TLTERVRRNPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNTVIIATS
                     NAGFGYEANLTEDADKPELMDRLKPFFRPEFLNRFNAVIEFSHLTKEDLSKIVDLMLA
                     EVNQTLAKKDIDLVVSQAAKDYITEEGYDEVMGVRPLRRVVEQEIRDKVTDFHLDHLD
                     AKHLEADMEDGVLVIREKA"
     gene            complement(30731..31213)
                     /locus_tag="VYO11_000716"
     CDS             complement(30731..31213)
                     /locus_tag="VYO11_000716"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HEV1595313.1"
                     /translation="MSKEVIVESFELDHTIVKAPYVRLIGEETGPKGDIISNYDIRLV
                     QPNEDSIPTAGLHTIEHLLAKLIRTRIDGMIDCSPFGCRTGFHMIMWGRHTSAKIAAV
                     IKDSLKEIAETTTWEDVPGTTIESCGNYKDHSLFSAKEWAKLILEQGISDDAFERHVI
                     "
     gene            complement(31308..32792)
                     /locus_tag="VYO11_000717"
     CDS             complement(31308..32792)
                     /locus_tag="VYO11_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008535024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HEV1595314.1"
                     /translation="MKKQAFSSEQYLNLQRDHILERINQFDGKLYLEFGGKMLEDFHA
                     ARVLPGYEPDNKIKLLQELKEQVEVVIAINASNIEHSKARGDLGISYDQEVLRLIDKF
                     NELGIFVGSVVITQYAGQPAADAFRNQLEKNGIDSYLHYPIKGYPTDMDHIISPEGMG
                     KNDYIKTSRNLIVVTAPGPGSGKLATCMSNMYHDQINGIKSGYAKFETFPVWNLPLHH
                     PVNLAYEAATADLDDVNMIDPFHLQTYGETTVNYNRDIEIFPVLKRMLERILGKSPYA
                     SPTDMGVNMVGFAITDDEAAVEASKQEIIRRYYQTVLDFKAEKVGEAAVKKIELLMND
                     LGITPADRKVAVVARQKAEETGGPALAFELPNGEIVTGKNSELFGPTAAALINAIKKS
                     ADIAKEVKLIEPEVVKPIQGLKIDHLGSRNPRLHSNEILIALAITATENPDAARAMEE
                     LGNLKGSEAHSTIILTDEDKNVLRKLGINVTFDPYYQYDRLYRK"
     gene            32945..34555
                     /locus_tag="VYO11_000718"
     CDS             32945..34555
                     /locus_tag="VYO11_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001156816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HEV1595315.1"
                     /translation="MQEKWWHNAVVYQVYPKSFMDSNGDGIGDLPGITSKLDYLAKLG
                     ITAIWLSPVYDSPMDDNGYDIADYQAIATIFGTMEDMDQLIAEAKKRDIRIIMDLVVN
                     HTSDEHAWFVEACENPNSPERDYYIWRDEPNDLDSIFSGSAWEYDEKSGQYYLHFFSK
                     KQPDLNWENEKLRQKIYEMMNFWIDKGIGGFRMDVIDMIGKIPDEKVVNNGPMLHPYL
                     KEMNQATFGDKDFLTVGETWGATPEIAKLYSDPKGQELSMVFQFEHIGLQYQEGQPKW
                     HYQKELNIAKLKEIFNKWQTELGVEDGWNSLFWNNHDLPRIVSIWGNDQEYREKSAKA
                     FAILLHLMRGTPYIYQGEEIGMTNYPFETLDQVEDIESLNYAREALEKGVPIEEIMDS
                     IRVIGRDNARTPMQWDESKNAGFSTGQPWLAVNPNYEEINVQEALANSDSIFYTYQKL
                     IQIRKENSWLIRADFKLLDTADKVFAYIRKDGDRRFLVVANLSNDKQNFSVDGKVRSV
                     LIENTAAKEVLEKQVLTPWDAFCVEMTD"
     gene            complement(34633..35467)
                     /locus_tag="VYO11_000719"
                     /pseudo
     CDS             complement(34633..35467)
                     /locus_tag="VYO11_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000547411.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(35415..36800)
                     /locus_tag="VYO11_000720"
                     /pseudo
     CDS             complement(35415..36800)
                     /locus_tag="VYO11_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677226.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISNCY family transposase"
     gene            36977..38422
                     /locus_tag="VYO11_000721"
     CDS             36977..38422
                     /locus_tag="VYO11_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000091082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HEV1595316.1"
                     /translation="MSRRFKKSGSQKVKRSVNIVLLTIYLLLVCFLLFLIFKYNILAF
                     RYFNLVVTALVLLVALVGLLLIIHKKAAKFTIFLLVLSILVSSVSLFAVQQFVGLTNR
                     LNATSNYSEYSISVAVLADSEIENVTQLTSVTAPTGTDNENIQKLLADIKSSQNIDLT
                     VNQSSSYLATYKSLIAGETKAIVLNSVFENIIESEYPDYASKIKKIYTKGFTKKVEAP
                     KTSKNQSFNIYVSGIDTYGPISSVSRSDVNILMTVNRDTKKILLTTTPRDAYVPIADG
                     GNNQKDKLTHAGIYGVDSSIHTLENLYGVDIHYYVRLNFTSFLKLIDLLGGVDVYNDQ
                     DFTSLHGKFHFPVGNVHLDSEQALGFVRERYSLADGDHDRGRNQQKVIAAILQKLTSS
                     EALKNYSMIIDSLQDSIQTNMPLETMINLVNAQLESGGTYKVNSQDLKGRGRTDLPSY
                     AMPDSNLYMMEINDSSLASVKTAIQDVLEGR"
     gene            38424..39155
                     /locus_tag="VYO11_000722"
     CDS             38424..39155
                     /locus_tag="VYO11_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine protein phosphatase"
                     /protein_id="HEV1595317.1"
                     /translation="MIDIHSHIVFDVDDGPKSREESKALLTEAYRQGVRTIVSTSHRR
                     KGMFETPEEKIAENFLQVREIAKEVASDLVIAYGAEIYYTPDVLGKLEKNRIPTLNNS
                     RYALIEFSMNTPYRDIHSALIKILMLGITPVIAHIERYDALENNEKRVRELINMGCYT
                     QVNSSHVLKSKLFGEPYKFMKKRAQYFLERDLVHVIASDMHNVDSRPPHMAEAYDLVS
                     QKYGETKAQDLFIDNPRKIVMDQLI"
     gene            39164..39856
                     /locus_tag="VYO11_000723"
     CDS             39164..39856
                     /locus_tag="VYO11_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000664160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular biosynthesis protein CpsC"
                     /protein_id="HEV1595318.1"
                     /translation="MKEQNTIEIDVFQLLKTLWKHKLIILLVALVTGAGAFAYSIFIV
                     KPEYTSTTRIYVVNRNQENKPGLTNQDLQAGTYLVKDYHEIILSQDVLEKVATNLKLD
                     IPVKTLTSKVQVTVPADTRIVSISVKDKQPEEASRIANSIREVAAEKIIAVTRVSDVT
                     TLEEARPATTPSSPNVRRNTLVGFLGAAAVTVITVLLIELFDTRVKRPEEVEDVLQMP
                     LLGVVPDFNKMK"
     gene            39866..40555
                     /locus_tag="VYO11_000724"
     CDS             39866..40555
                     /locus_tag="VYO11_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein kinase"
                     /protein_id="HEV1595319.1"
                     /translation="MPTLEISQAKLELAKKTEEYYNALCTNLQLSGDDLKVFSISSVK
                     AGEGKTTTSTNIAWAFAHAGYKTLLIDADMRNSVMSGVFKSRERITGLTEFLSGTTDL
                     SQGLCDTNVENLFVIQAGSVSPNPIALLQSKNFSTMLGTLRKYFDYIVVDTAPIGIVI
                     DAAIIMQKCDASILVTKAGETKRRELQKAKEQLEQTGKSCLGVVLNKFDTSVDKYGFY
                     GSYGSYRKQKK"
     gene            40570..41931
                     /locus_tag="VYO11_000725"
     CDS             40570..41931
                     /locus_tag="VYO11_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001013545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HEV1595320.1"
                     /translation="MNEKLAKSSVAIVQSFLVILLTYLLSAVRETEIVSTTAIVLYIL
                     HYFVFYISDYGRNFFKRRYLIELVQTLKYILFFALAISISNFFLEDRFSISRRGMIYF
                     LLLHVFLVYMLNLFIKWYWKRAYPNFKGSKKVFLLTATSHVEKVLDRLIESDDVVGEL
                     VAVSVLDKPDFQHDDLKVVAEGEIVNFATREVVDEVFINLPSEKYNIGELVSQFETMG
                     IDVTVNLNAFDWARNKQICEMAGLNVVTFSTTFYKTSHVIAKRVIDIIGSLVGLILCG
                     LVSIVLVPLIRKDGGSAIFAQTRIGKNGRHFTFYKFRSMCVDAEDKKRELMEQNTMQG
                     GMFKVDDDPRITKIGHFIRKTSLDELPQFYNVLKGDMSLVGTRPPTVDEYEHYTPEQK
                     RRLSFKPGITGLWQVSGRSEIKNFDEVVKLDVVYIDGWTIWKDIEILLKTVKVVLMKD
                     GAK"
     gene            41963..43141
                     /locus_tag="VYO11_000726"
     CDS             41963..43141
                     /locus_tag="VYO11_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 1 protein"
                     /protein_id="HEV1595321.1"
                     /translation="MKKSVYIIGSKGIPAKYGGFETFVEKLTEYQKDGNIQYYVACMR
                     ENSAKSGFTADTFEYNDAICYNIDVPNIGPARAIAYDIAAVNKAIEIAKKNKDEAPIF
                     YILACRIGPFIARLKKKIQAIGGTLFVNPDGHEWLRAKWSLPVRKYWKFSEQLMVKYA
                     DLLVCDSKNIEKYIQNDYKQYQPKTTYIAYGTDTSPSILKSEDLKIRSWYQEKGLSEN
                     GYYLVVGRFVPENNYETMIREFIKSKSKKDFVLITNVEQNKFYDQLLQETGFDKDPRV
                     KFVGTVYDQELLKYIRENAFAYFHGHEVGGTNPSLLEALASTKLNLLLDVGFNREVGE
                     DGAIYWRKDNLHKVIEESEQKTIEEIKEIDILSTEQVEKRFTWDFIVNEYENLFLLGK
                     "
BASE COUNT        13309 a         7477 c         9406 g        12981 t
ORIGIN      
        1 attctattgg agatgtgtat gagcaggaat ggatatatga aatagaaaaa gaaggagaaa
       61 aacgttttgc agaagctatt ccaccgggat ttaatgacga aaataaagat ggaataagaa
      121 aatataatgg catatcttat catcaaaaat atggtgattt aattatttgg aaggatatat
      181 taaaaaaagc aacggaacaa cctcgtggtg ataaagttat ctttattact aatgacggag
      241 aatcaaataa aaaaagtgat ttaatttata aaacttcaaa tatgaaagtt ggtccaagta
      301 ttttcttgat gaatgaatta tatatgtgta gtagaaaaaa attatatata ttaaacaata
      361 ctacactcgt aaacatgatt acagagttat cagaagatga aattgatagg atagaggccc
      421 aggaagaaaa gaagtatgtt gttacgtttc caaaatggat tttagataaa gcagaaaaag
      481 atgtgcgagc aagaaatgag tcaaataact cgagtgttgt atattatatt gattcagaaa
      541 ataggttagc tagcattgat attgatgaag ttgaaccgct tgaactcata tccctgctag
      601 agaatcctga tgtaaaaaaa atgttaaaag aagaaatttt gaagaaaatg ttagatagtt
      661 attacagtaa attaccaaga catattatta aagacataat aaatagttat caagaaaaaa
      721 atattcaatg aatttaataa taaaatttca tcatttaggg caaattactg ataaagctga
      781 ctcgttttgg ttggttttgt agaaaaattt gccctattta gatgaaaatg gttgaaatta
      841 gttgagaact agtaaatatt tggtagttaa aaatggtttg attaaaggta attgaaagaa
      901 cttagttatt aggttagcca aaccaggtct taagaaagct cgtaaagcat cacaatttag
      961 taagcgttaa ttcgaaagaa ttactatact tatacagagc acctttcggg gtgttctttt
     1021 tttatacttt cttactaaat tggtgtaatt gacacagttg ttgcgacttt agtcgcttac
     1081 aaatgtggct gcaacctgac aaggttagtt gcctcaaaac gttaatcaat acgattatat
     1141 caacgtttca aagcactcaa aagttcacct tatttttata gtaaaatgaa ataagaatag
     1201 gacaaatcga tcaggacagt caaatcgaat tctaacaatg ttttagaagt agaggtgtac
     1261 tattctagtt tcaatctact ataccttatt gttttagaga ctttaaagca aattcaccta
     1321 ctgtcatagg aactacatta gaagtattta cataaatctg tgttgttcct gtgtcactgt
     1381 gtgttagagc cttagaaatg gcttctaagc tcattcctgc ttttttagca agtgtcgctc
     1441 ctgtatggcg taatttgtga ggtgtagcgt gtgtcagttc tttatgtcgc tttctaatgc
     1501 ttttcatttt attgttcaga tagtcggcat gtaaaggctt gttgatgttt ccttttgtgt
     1561 cgatatatgt aaaaacaaat tgttctggat tactgaggat gccaaacttt gctagttcat
     1621 atctttgttg ttctttccaa gaggtaagaa gttgaagtaa atcattagaa atagagaaaa
     1681 ataggatagc aaaagctcta tttcaggaga aaatgaagca aatatttcca taataaaacg
     1741 catattatca aggttgttca atacctgata ctatgcgctt ttctgatttt aaagactgat
     1801 tgctcagtct ctttttcatt ataattcagt tacaatttaa tcttatttga gaaagtgggt
     1861 gatgctattc tctaataaga ctatgatatt aatttttgat agtacttcca gaaattatag
     1921 atcccctttc atccccaatt tctattttca agtgtccgta ttatatagcg tattcgaaat
     1981 tcactatatc ttgttaggat ttgggtagaa tcattgataa cagactgttg caaatctaat
     2041 tagctgtatg atttatattt atctattttt ctagtaacca atctataatg tttttcttct
     2101 cgattccatt gtaattggct gttggctgaa tcgtatccat tgttaataga tactttggga
     2161 attgatcttt aatggcgtct agtggtctaa gttctctttc tagtgtttct ggagcaagtg
     2221 ttgtttcact gacttgataa taagcgtagt gaccaagatc agttacaaca acaaaatcaa
     2281 cctcatattt atctaaatta ccaacatata cttgtgaata tctacgtctc aattccaaat
     2341 agaccatatt ttccaagata tggccaatat cttctttgtg gtctggcaat aagaggtgtc
     2401 gtaaacctaa atcaacggga taatattttt ctaagcgttg caataatgct ctacctttta
     2461 catcaaaacg tggaacggaa taaaaaagca aactatctgt caaagtcgtc aaataatttt
     2521 ccaaagtatt atgggagatt gaaacgtttt ggctgaccag ggtattgcga atcttatttg
     2581 ttgatattaa gctacctgta ctactgagaa gggttcggac aatgcgctca ataatagtag
     2641 gatttggatt tcccaatcta gtgacaatat catttaacag tatggagtta tatattcctc
     2701 ttagataatc aattttttca gcgtaagatg atgtttgcaa taagtaaggg aaagcactaa
     2761 agagataatt gttaaaaatt tctgttgtat tcagattttc tgtgagagat tgacctgata
     2821 gatattcttc aaatgacaat ggaagaactt ctatctcaac ataccgaccg gtcaagtttg
     2881 tagctaattg gctactcata aagtaggcgt ttgatccagt caaatagagg tcaacatttg
     2941 gtagtataaa tagactatct gctaccagtt caaatttttc aacatgttga atttcatcta
     3001 aaaagatata gtatgttttc tctccaatta actgctcttt tatataagca aataatgttt
     3061 gaaaatgtcg gagatcatag taactcagat cctcaaaatt gatggatatg atttgatcct
     3121 cgtctacccc agttgctatt aactcctctt tatagagttg aaagagaaca gatttaccag
     3181 ctcgcctaac tccactcaca actttgatga tttgtcggtc acgatgtctt cttaaaaaat
     3241 ctaaataatg tggtcttttg atatagttca taatagttac ctcaaagata gtataataca
     3301 aatagatgtt attttcaaat atttagaaat aatgtttaat ttatttaatt atttctaatt
     3361 gtttagaaat aatatctgga actatttaaa tatcttcaag atagaaaaag aaattgtact
     3421 tgttgatgtt gaatcatttg tgttaacaag tcatttagaa gcatttaaga aattagtgaa
     3481 atgaaaaact catggcagaa caaattgttg ggtatatggt ctattactaa caactactgc
     3541 tagtttatga gatagatatt taattattct cggataaata ggataagcgt gctgaaaact
     3601 tagatatgac aaacaaaata aaatttttaa aagctacata gaaacatggt ataatgtatc
     3661 taaaggaggt agcatatgtc cttagatata gataaagaaa agatgacaat catgggaata
     3721 gcttttgaaa acagatccgt ttttaagagt gtttggtatg ctttaagtac aaatatgatt
     3781 gaaggatggc gacctacggt tagtgatgtt gaaaaattac gagatgaagc tcttgctctg
     3841 gggatgactt aatgaagcgc aactgttatg aatcttatga ctatgttgat ccggataatt
     3901 tatataccga tccgggttct tcagttctaa gaaataagca ggaaggaaaa aagcacgtga
     3961 gcttgaatat cgtatgattg ctagtaagag tttgaaatta tttatcaatc ctatcttagt
     4021 taatagttta aaagtagttt gtttcacaac tgcataagct tagaaaagtt gaaaagtgat
     4081 aactctttaa taaactcttg gtttgttaaa agatattttg tccactgcat tttttcaatt
     4141 gactattatt tgtcatagat ataacagata gaacattgca ttcagaataa tgaaaaacgc
     4201 atcaaaaatg gtgcgttctg tttttatgct accataaaag gaggaaaaca aattgaaaat
     4261 ttttaaggga gagttttatc gaatctctgt attaacagac aagctagtaa ggttagaata
     4321 ctctcgaact ggaaattttg aggatagaac gacacaactt atctataata gagattttgg
     4381 ccaaatttcg ttagattata tcgagacatc aaatgtacta gatattatga cggactattt
     4441 tcatctgcac tttaataaag gagaatttaa cgccgaaaat ttatttatag aattaaaagg
     4501 aaattttgcc gtatatggta gtcgctggta ttttggtgaa tctattgaaa cgttaaaagg
     4561 aacagctcgg actctggata aggcagatgg agcaatctcg ttagaagatg gaattattag
     4621 ccgaaatggt atagccttat tggatgattc tcaaggattt atttgggatg aacagtctgg
     4681 ttatattgag agagaaaatc aaattgacct gtatttcttt gcctatgggc atgattatag
     4741 aggagcaatc agagactttt accatttgac tggttcaaca cccttgttgc caagatatgc
     4801 tttaggcaat tggtggagta gatattggcc ttatacgtcg gatgaatact tggatttaat
     4861 agacagattt gaaacagaga aaattccatt atctatcggt gtgttagata tggattggca
     4921 tataactgac attccagctc gttttggaag tggctggaca ggatatagtt ggaatagaaa
     4981 cttaatacca aatccagaac agttattgca acaacttcat gatagaaagt taaaactctc
     5041 cttaaatgtc catcctgctg atgggatacg ggcttatgaa gaagcttatc ctcaaatcgc
     5101 aaaacgattg gggttaaatg tagaactaga agaacctgct atttttgatt tttttaatcc
     5161 ctcttttagg gaagcctact ttaaagatgt tcattatgag ctagaaaagc agggagtaga
     5221 tttttggtgg attgactggc aacaagggac acaaggtatg ctagatccac tttggctttt
     5281 aaaccattat cactatcaag atagttgtaa aaatgcagaa ggtggtttga ttttatcaag
     5341 atatgcaggt cctggtagtc accgctaccc tgttggtttt tcaggggata ctattattag
     5401 ttggaattcc ttaagatttc aaccctattt tacagcgaca gcatctaata tcggttatag
     5461 ttggtggagt catgatatcg gtggacatat gttgggggat tatgacgaag agctacaaac
     5521 tagatggcta cagtttggtg tttttagtcc gattactcga ttacatagtt ctagaagtcc
     5581 ttttaatagt aaagaacctt ggttcttttc agaaacaaca tctaagatta tgaagaaata
     5641 ccttcgtttg agacatcaga tgattcccta tctatatacc atgaatgtaa agacacatga
     5701 ggaaggtgcc ccattaatca gtccaatcta ttatttctat ccagagaatg atgagagcta
     5761 taatgttcca aaccaatact tttttggaac agaactgatg gtggctccca ttgtagaaaa
     5821 gatggatttg acattccaat ctgcaaaagt agatgtatgg ttccctgaag gtgaatggta
     5881 tgacttcttt tcagagaaaa aatacacagg tggtgtgaag ttaagtgttt atagggacat
     5941 ctcgactacg cctgtgtttg caaaaagtgg tgcaatcatt cccttggttg gttctgagat
     6001 aggtatgggt gttgatttac ctgaggttgt agattggtat gtattcccag ggaaacaaca
     6061 ttcttttgaa atgcttgaag atcaaaatgg tcaaagatat aaaacaagat tatcaatcga
     6121 ttgggaaatg ggaatggtag agttagcatt acaaggagat tctagtatcg ttccaagcaa
     6181 tagaaaacat agaattcatt ttaaaggaac gaatgtgtct ataattgaat tgccaaataa
     6241 gaatgataca gctaaatttg aatggaaaga taataaaagg acatctttaa atgacgaagt
     6301 ttttagacta ctaaagacag cttctcttcc atatgaatta aaagatagat tgttaaatca
     6361 attcatcaat gcgaaaaact ctcatgactt aatgaatatc ttgcatcatc aggataagga
     6421 attgagaggg cgtttgttgg aaatgatatt tactagccaa aactaattga tataattaga
     6481 aagtcatttg tttagtgtat atgaagattc tgtatggtat tcgttatcac tggtcacatt
     6541 gaaaatgtga aataagcacc tacaacatag actttacaac acttcatgtt tcatatcatg
     6601 gggtgttttt ctatttaagt caaagcccat caaaaaatct cactattcat caggttaaag
     6661 gaaacctaat catagtgaga ttgtgaatta tagtagagtt tgtatcgcct cttcaatttg
     6721 ttttgggtct gtttttgaag aaaagcgttc aaagacttgc ccatctcgac cgatgagaaa
     6781 cttagcgaaa ttccattcga ctcgttttcc tagtgggccg gatttctggt cttgtaacca
     6841 gacatagaga gggtctgctt ccttaccgtt gaccttaatc ttggcaaaac gtgggaaggt
     6901 ggtttgaaaa tgtaggctac agaaggcgtt gatttcctct gcgctgccgg gtgcttgtcc
     6961 cataaactga ttgcaaggga aatccaatat ttcgaagccc tgatcttgat agcgttcata
     7021 gagttcttga agtccctggt actggggcgt taaaccacat ccagtagcag tgttgacaat
     7081 caagagaact ttgccacgat agctatccaa gggagttgct tggttgtttt ggttcaaaac
     7141 ggaaaaatca taaagtgaag tcatgagggc ctcttttctt tttctacatt gtaacagttt
     7201 ttactttttt cgtcgagtcg gatggaagat attgttgaag aataagcctt caatatgata
     7261 gaaaccgttt acaaataact ttaaaaatgg tatgatttaa ttaaaccggt ttacttagtt
     7321 gctataaatc tctaatttga gatttagttc ctattgattt tacaatatgt ttattggagt
     7381 gtatacatgc aaacaaaaac aaagaagctc attgtgagtt tgtcttcact tgttttatca
     7441 ggatttttat taaaccatta tatgacaatt ggagcggaag aaacgactac gaataccatt
     7501 cagcaaagcc agaaggaagt tcagtatcag caaagggata caaaaaattt agttgaaaat
     7561 ggtgattttg gtcagacgga ggacggaagc agtccgtgga caggaagcaa agctcagggg
     7621 tggtcagctt gggtagacca gaagaatagt gcagctgcct caactcgagt cattgaggct
     7681 aaggatgggg ctatcactat ctcaagccat gagaaattaa gggcagcgct tcaccgtatg
     7741 gttcctattg aagctaagaa aaagtataaa ctgcgtttca agattaaaac agataataaa
     7801 atcgggattg ccaaagttcg tatcattgag gaaagtggta aggacaagcg attgtggaat
     7861 tctgcaacga cgtcaggaac aaaggactgg cagaccattg aagcagacta tagcccgact
     7921 ttagatgttg ataaaatcaa gctggagtta ttctatgaaa caggaactgg gactgtttcc
     7981 tttaaggata ttgagctggt agaggtagca gaccagcttt ctgaggattc tcaaacagat
     8041 aaacagcttg aggaaaagat tgatttacca attggaaaaa aacatgtttt ttctcttgcg
     8101 gactatactt ataaggtaga aaatcctgac gttgcttcag tcaaaaatgg aattttagaa
     8161 cctcttaagg aagggacaac caatgtcatt gtcagtaaag atggcaagga agtgaaaaag
     8221 attcctttga agattctggc ctctgttaag gatgcataca cagaccgttt ggatgactgg
     8281 aatggcatca tcgctgggaa tcaatactat gattctaaaa atgaacagat ggccaaatta
     8341 aaccaggaat tggaaggaaa ggtagctgat agcctatcca gtatttcaag tcaggcggac
     8401 cgcacctatt tgtgggaaaa attttcaaat tataaaacgt ctgcaaatct gactgccact
     8461 tatcggaaat tggaggagat ggccaagcaa gtgaccaatc cttcttctcg ttattatcaa
     8521 gatgaaactg tcgttcgaac agtcagggat tccatggaat ggctgcataa acatgtctac
     8581 aatagtgaaa agagcattgt tgggaactgg tgggattatg agatcggtac acctcgtgcc
     8641 atcaacaata ccttgtctct gatgaaagaa tacttctctg atgaggaaat taaaaaatat
     8701 acagatgtaa ttgaaaaatt tgtaccagac cccgaacatt tccgaaagac gactgataac
     8761 ccatttaagg ctctaggtgg aaacttagtt gatatgggaa gagtaaaagt aatagctggt
     8821 ttactgcgta aagatgatca agaaatttct tctaccattc gctcgattga gcaagtgttc
     8881 aagttggtag accaaggtga aggtttttat caagatggat cctatatcga ccacaccaat
     8941 gttgcctata cgggtgctta tgggaatgtt ttgattgatg gcctgtctca actgttgcca
     9001 gtcattcaaa agaccaagag tccaatcgat aaagataaaa tgcaaaccat gtaccactgg
     9061 attgataaat cgtttgctcc tttgctggtg aatggagaac tgatggatat gagtcgtgga
     9121 cgctcgatca gtcgtgcaaa tagcgagggg cacgtggccg cagtagaagt actaagaggg
     9181 attcaccgaa tagcggatat gtctgaagga gaaaccaaac aacgtttgca gagtcttgtg
     9241 aagaccattg ttcaatcgga tagttattat gatgtcttta agaatttgaa gacttataag
     9301 gatatcagtt tgatgcaatc cttgttaagt gatgcaggag tcgcaagtgt tccaagacca
     9361 agttacctat ctgcctttaa caagatggat aaaacagcca tgtacaatgc agagaaaggg
     9421 tttggatttg gcttgtcact cttttccagt cgtaccttga attacgaaca catgaacaag
     9481 gaaaataaac gtggttggta tacgagtgat gggatgttct atctttacaa tggcgatttg
     9541 agtcactata gcgatggcta ctggccaaca gttaatccat ataagatgcc tggtacaaca
     9601 gagacggatg ctaagagagc ggatagcgat acaggtaaag ttttaccgtc tgctttcgtt
     9661 ggaacgagca aactagatga tgccaatgcg acagcaacca tggatttcac caactggaat
     9721 caaacattga ctgctcataa gagctggttt atgctaaagg ataagattgc ctttttagga
     9781 agcaatatcc aaaacacttc aacagatact gctgcaacta caatcgacca gagaaaactg
     9841 gaatcaagta atccatataa agtctatgtc aatgataaag aagcctccct tacagaacaa
     9901 gaaaaggatt atcctgaaac ccaaagtgtc tttttagaat cgtccgattc gaaaaagaat
     9961 attggttact ttttctttaa gaagagttca atcagcatga gtaaggcttt gcaaaaggga
    10021 gcctggaagg gtatcaatga aggacagtca gacaaggaag ttgaaaatga atttcttacg
    10081 attagtcagg ctcataagca aaatggagat tcttatggct atatgctcat tcctaacgtg
    10141 gatcgtgcca ccttcaatca aatgataaaa gagttagaaa gtagcctcat cgaaaataac
    10201 gaaacccttc agtctgttta tgatgctaaa caaggagttt ggggcattgt gaaatatgat
    10261 gattctgtct ctactatttc caaccaattc caagttttga aacgtggagt ctataccatt
    10321 cgaaaagaag gggatgaata taagattgcc tactataatc ctgaaaccca ggaatcagct
    10381 ccagatcagg aagtctttaa aaagctagag caagcagctc agccacaagt acagaattca
    10441 aaagaaaagg aaaaatctga agaggaaaag aaccattcgg atcaaaagaa tctccctcag
    10501 acaggagaag gtcagtcaat cttggcaagt ctagggttct tgctacttgg ggcattttat
    10561 ctattccgta gaggaaagaa caactaattt gttcatcatc tagatgaatt acatgaaact
    10621 gtggaaaata gaaaaaatcc gaagaaggcc aaatatcttc ggatttttct tttaaaaaag
    10681 gataagttga tacttatcct tttttacttc attattatgt gactatagcg ttttgaaact
    10741 agaatagaac gttataactg ctaaaagatt tctataaatt catttgattt tcctaatcaa
    10801 tttgttcgta tcctatttca ctccactata taagtccgtc tcgctccgtg aggtgcgcgt
    10861 cgaaggttat accaaaaaaa ctccaaacgc gatacaataa aggtattcaa tccaattgta
    10921 aagcgaaagg agaaaaaata tggcacaaaa gactcatagt ttatcataca caaagtggat
    10981 gtgttctatc atattgtgtt cacccctaag tatagacgaa aagtcatcta taatcaatat
    11041 agaagtagtt taggcgaaat atttcatcgc ttgtgtagtt ataaaggtgt tgaaatgatc
    11101 gagggtcact taatgccaga ccatgtacac atgttagtca gtattccgtc gaggctaagt
    11161 gtttcaagtt ttatggggta tttaaaaggc aaaagtgcac tcatgatgtt tgacaaacac
    11221 gccaatctca agtacaagtt tgggaatcgg aatttctggg cggaaggtta ttatgtaagt
    11281 ccagtagggc ttaatgaagc cacaattaag aaatatagtc aagattaaag aaattatcga
    11341 gtggatgatt tcttcacgag tatgaaaatt tgagaactag taaagtatga tatatagtaa
    11401 aatgaaataa gaacaggacg aaatcgatca ggacagtcaa atcgattttt aacaatgttt
    11461 tagaagtaga ggtatactat tccagtttca atctactata gcactagata aattgagtgt
    11521 aaaagaatat gaggatccct ttagggatag tggtaagtaa taccaaagtc tcttaaagag
    11581 gcaagtgacg agtcaagagc aataagtctt gaacaacgtg aaagccagcg tctttaggcg
    11641 ctggctgatg atttgggctt atagctctga gataaaccac ccgttagacg ggtagttatg
    11701 attttatctg agtgtaatat actgttgggc aatctcgctg atgcggtcaa agttgccttg
    11761 ggaagcgagt ttattgagtt cgccaccaat tccaacggca tctgcaccag cagcgaacca
    11821 ttgagggatg ttgtttaggc cgactcctcc ggttaccatt acggaaactt gtgggatcgg
    11881 tgccttgact gcagagatat atgctggact gagagtacta cctgggaaga gtttgatgat
    11941 ttcactaccg gcttcaagtg cagtcgtgat ctctgtgagg gtaatacagc ctggaatgta
    12001 cggtgtgctg tagagattgc acattttcgc agtttcagca tggaaagatg gagaaacaac
    12061 gtaatttgct ccagctagaa tggcatctct agcagttacg gcatcaagca cagtacctgc
    12121 accgatacaa acactctgat cgtcctgata caagtctaca agttccttga tgatttgtcc
    12181 tgcatactga ttggtatagg cgatttcaat agctttgata ccgcccttga tacaagcaat
    12241 cgaggcttgt agtccttctt cctttgtatt tcctcgaatg acagcgacaa ttttctgttt
    12301 ttttagttca ataatcgtat ctgatttggt catgtaattc tcctaacgaa tgatatcttg
    12361 tgcatttgcc agtaaatttt caatactagt tgcggaagtg gagagatggt ctcctggaag
    12421 agtgcatttg agagttgcgc tcgcaactgc aaagtcaatg gtagttttta gggaggaatg
    12481 atggagtagt tggtaaaggg caccagatat aaaggcatcc ccgctaccaa ttcgttgata
    12541 gactgcagtt tttagttgga cagactcttc aaatcgttct tccagagcat aggcttgata
    12601 gacatttttg tcttgctcat cactagatcg gagggtatgg aaaatagcct tgaaaccata
    12661 ggtttctttt aaaagtcgca tgcgattttc cacctcttct aggctagcac tgtctcttgg
    12721 aaacatctct agattttggt catcaatcat gagaggatca ataccgaagc aatagtcagt
    12781 aaaacgtgca aacttagaaa attcatactt ggcttctagg gctgaaatca tctttgttct
    12841 cagattgaga tccattgaaa cgacaattcc tcggcgcttg gcttcttcca agagtaggag
    12901 aaggatcgca cggacctctt gaccgatagc tatggtgatt ccactaaaat gaaaatggct
    12961 aatcccctga aagagagaat ccatatctag catgtttggc cgaatctggc tgatactcgt
    13021 atgcttacga tcgtagaaaa cttcactttg acgacaacca aagccgttct ccaaatagta
    13081 gaggccgatt cgatcgccaa gccgacagat tgaactggta tcgatttggt gctgtttcaa
    13141 gaatgtgaga aaacgatctc caatctcgtt ggcagggagt gcggtaaaga ctttcgttga
    13201 gatacccagg gcttgcaaat tacaagcgat gttaatttct gatccgccaa aataagtcga
    13261 actggcaaca tgatcgccga tactggtggc atctaatggt gagattcgaa ttaatggttc
    13321 gccaaacagt aatattttcg tcatccatta gttcctttct ggtttagaat agctttactt
    13381 ggctaatact tctttcaaat aagcagcgac ttcatcatct tggcagtttt caaagaagta
    13441 ttcttggaag tatttgccag agatggtgtc tttgaggaag tcttggtcga ttgttttaag
    13501 gatggtcatc aaatcattgt gggtgatttg tttcacctcg tttaagatac gagcgttgcg
    13561 ttgttcaggg attacacgtt ctcttgggta gccaccgccc atttcttcag caaataagcg
    13621 ttcaaacatc aatttgaggg tcagttctgc cccccagcca aatcctttgg cataagggat
    13681 agacaaggcg ttaccaccat tgatttgaga ataaaggtaa gcgtcagttg ggtccactgc
    13741 tagaccacag acaataccag ggaagctgtt taaagcaagc atagccccta cacccgtacc
    13801 acagccggta acaacaaagt caactgcctt tgtatttaaa aggatggcag ccattagtcc
    13861 gttctgcaca taagttaatt gactttctcc ttcttctcca cgcataccat agttaaataa
    13921 ttggtagcct tttttatctg tcgcttcttt tagactatcg taaataatgt gattcttgct
    13981 agcttgacta ttttcattga ttaatgcgat tttcataaga tcttctttct atttttactc
    14041 aggttgtttt ccgatgtagg ctaagatacc gccatctaca tataggatgt ggccattgac
    14101 aaaattgctg gcatcactag cgagaaagac agcagggccc atcaaatctt caggatttcc
    14161 ccaacgtgca gcaggtgttt ttgcaatgat gaactggtca aatgggtggc gagaaccatc
    14221 ttcttgcaac tcacgaagag gtgctgtttg aggagtggca atataacccg gtccaattcc
    14281 gttacattgg atattggctc caccgtattc agacgcaatg ttgcgggtca acattttcaa
    14341 gcccccttta gcagcagcat aagcgctaac tgtttcacgt cccagttcgc tcatcatcga
    14401 acaaatattg ataatctttc catgcccttt ctttatcata gaaggaataa ctgcctttga
    14461 aacgataaat ggtgcgttta agtcaatatc gatgacctta cggaaatcag cggcgctcat
    14521 ttcgcacatt ggaactcggc ggataatacc agcgttatta acgaggatgt caatgacacc
    14581 aacctcttgt tcgatttgct tgaccatggc ttggataccg tcctcgtctg tcacgtcata
    14641 gacatatcca tgggcttgga tgccaacttc acgataagct tcaatccctt tattgaccag
    14701 atcttgattg atatcgttaa agacaatagt agcgccggct tcagcgtagg atttggcaat
    14761 agcaaatcca attccataag aagcgccggt gatgagagca atttttcctt ttaaagaaaa
    14821 ctgctcaatt gagaatgatg tatttgtcat ttgatacttc ctttcaaatt tgttaagact
    14881 tctctataat caaattatat tctagtaaac cggttttgtc aataaataaa tatttttatt
    14941 tataaaaagg tttgttttcc taaaaaaacg gaagattttg aaatttctgc ctattaaaat
    15001 ggttaaaaag ataatgaaag cgctaatatt tttttaaaaa aactattgac aagataaaaa
    15061 taaaggatta caatggggaa tataaagtaa accggtaaac ttaaacaaga aaggagaaaa
    15121 gatgaaaatt gtacttgtag ggcatggaca ttttgctaca gggatttata gttctttaca
    15181 attgattgca ggtaatcaag aaaatgtgga ggcgattgac tttgtggaag gaatgtcagc
    15241 agatgaactc aagcaaaaaa tcttacttgc aatttcaaat gaagaagaag ttttaatcct
    15301 aagtgatctc ttgggaggat cgccattcaa ggtttcttct accataatgg gagaaaatcc
    15361 agtcaaaaca atgaatgttc tctcgggttt gaacttagcc atgttaatgg aagcagtctt
    15421 tgctagaatg gctcatagct ttgatgaggt tgttaataaa tcagtagtgg cggcccaggg
    15481 cggagtcgta aatggtaaag aattgttttc aacggatgca gaggaagaag atttcgaatt
    15541 gggtatttaa agggtaaaag aatgataaaa aaggttacga ttgaaaaaat aaaatcgcct
    15601 gagcgcttct tagaagtacc acttctgacg aaagaagaag tcggccaggc aatcgataag
    15661 gttattcggc agttagaact caaccttgac tatttcaagg aagatttccc gactccagct
    15721 acctttgata atgtctatcc aatcatggat aacacggaat ggaccaatgg tttctggaca
    15781 ggagaactgt ggttggctta tgaatacagt caacaggatg catttaaaaa catcgctcat
    15841 aaaaatgttc tttctttcct ggatcgtgtc aataagagag tagaattgga tcaccatgat
    15901 ctcggcttct tgtacacacc gtcttgtatg gctgaatata agataaatgg agatggagag
    15961 gctagagaag caaccttgaa agctgcagat aagttgattg aacgctatca agaaaaaggt
    16021 ggttttattc aagcttgggg agacttgggc aagaaagagc attaccgttt gattatcgac
    16081 tgcttgctca atatccaact cttattcttt gcttatcaag aaacaggcga tcaaaaatac
    16141 tacgatattg cagaaagcca tttctatgct tcagctaata atgtaatccg tgatgacgct
    16201 tcgtccttcc acaccttcta ttttgatcct gagacaggtc aaccctttaa aggtgtaacg
    16261 agacaagggt atagtgatga ttcatgctgg gcacgtggtc aatcatgggg agtctatggt
    16321 attcctttga cttatcgtca cttaaaagac gagtcctgct ttgacttgtt taagggtgtg
    16381 accaattatt tcttgaatcg tctgccaaaa gatcatgtgt cctattggga tttgattttt
    16441 aatgatggta gtgatcaatc acgagattct tcagcaacag ctatcgccgt ctgtgggatt
    16501 catgaaatgc taaaacatct tccagaggtg gatgctgaca aagatattta taaacatgct
    16561 atgcatgcca tgcttcgttc cttgatcgaa cattatgcaa atgatcaatt tacccctggt
    16621 gggacaagtc tcctccacgg tgtgtactca tggcattcag gtaaaggagt ggatgaaggc
    16681 aatatctggg gtgactacta ttacctagaa gcccttatcc gtttctacaa agactggaac
    16741 ctatattggt aggaggagaa atatgacaat gccaaatatt attatgaccc gtatcgatga
    16801 acggttgatt catggacaag gacaactttg ggtaaaatac ctaggttgta atacggtcat
    16861 tgttgccaat gacgaagtaa gcacggacaa gatgcaacaa actctgatga aaacagttgt
    16921 gccagactca gttgccatgc gtttcttccc tttgcaaaag gtgattgata tcattcacaa
    16981 ggctaatcct gctcaaacga tctttatcgt tgtaaaggat gtgaaggacg ctttaacctt
    17041 ggtagaaggt ggtgtcccta tcaaagaaat caatattggg aacattcaca atgctactgg
    17101 taaagagcaa gtgacacgct ccatcttcct gggtgaagag gacaaggcgg ccctcaagga
    17161 attgagccaa actcatcaag taacatttaa tacgaaaaca actccaacag gaaatgatgg
    17221 agctgttcaa gtcaacatta tggactatat ttaaaagagg agatcgttat gtcgattaat
    17281 gtatttcaag cgattttaat tggattatgg acagctttct gttttagtgg aatgctgtta
    17341 ggaatttaca ccaatagatg tattgttctg tcatttggtg tcggaattat tctaggtgat
    17401 ctgcctactg ctcttgcaat gggagctatt ggtgaattgg cttatatggg attcggtgtt
    17461 ggtgctggag gtactgttcc accaaaccca atcggacctg gtatctttgg taccttgatg
    17521 gctatcacta gtgctggtaa agtcagtcca gaagcggctc ttgccctctc tactccgatt
    17581 gctgtggcga ttcaattctt acaaactttc gcctacactg tacgtgctgg tgcgcctgaa
    17641 acagcgatga agcacttgaa aaaccataat ttgaagaaat ttaagttcac tctaaatgca
    17701 acaatttggt tgtttgcctt tattggattt accttgggtt gcttgggtgc cctttcaatg
    17761 gataccttgt tgaaactcgt agactacatt ccaccggtat tgcttacagg tttgacagtt
    17821 gctggtaaaa tgctcccagc tatcggtttt gcgatgatct tgtcagtgat ggctaagaaa
    17881 gagttgattc cctttgtctt gttgggatat gtttgtgcag cttatctaaa catcccaaca
    17941 attggtattg caattgtagg tactatcttt gctttgattg aattttataa caagccaaaa
    18001 acagcggatc atgtggtaga ggaggaagca cacgatgact ggatctaaca aattaacaaa
    18061 acgtgattat cttaaaacgt ctttgcgggc attcttttgt caaaatggat ttaactatag
    18121 taactatcaa gggttgggat atgccaatgt gatgtatcct gctttgaaaa aacactatgg
    18181 agaggatcag gaaggtttct accaagcctt ggaagaaaac tgtgaattct ataataccaa
    18241 cccacacttc ctgcctttta ttaccagctt gcatcttgta atgttggaaa atggccgtcc
    18301 ggcaaaagaa acacgtagca tcaagatggc cttgatggga ccattggcag gtattgggga
    18361 ttctctttct caattctgtt tagctccatt gttctcaacc atcgcagctt cgtttgctca
    18421 agaaggcttg gttgtcggtc caatcttgtt cttccttgcg atgaatacga ttttaacagc
    18481 gattaaattg tcaactggtc tgtatggata caaactagga acaactgtga ttgataaact
    18541 aagcgaacag atggcaacga tttctcgtat tgccaatatt atcggtgtaa ccgtaattgc
    18601 tggtttggca gcgacatctg ttaagattat ggtgccgatt acctttgctg caggggaagt
    18661 taaagcagac gctaaacaaa gtatcgtaag tattcaggga atgcttgata aggttgctcc
    18721 agctcttcta ccagccctat ttacactttt agtttactac ttgatcaaag aaaagaaatg
    18781 gacaacatat aaactcgtta ttttaacagt tatcatcgga attatcggaa gctggcttaa
    18841 gattatagct taatggatac aacattgttt tatggaatag tgattgtctt ggcagtgagt
    18901 ccccttttac tgtcaagctt tcattctatt cgtcagcaaa agttgcttcg caaacagatg
    18961 gagcaacgac aagagtattt agcttcttta acatctggtg atgaagtgtt gttattgtct
    19021 ggaattcatg gaaaaatcat ttctatccaa gatgacttgg tctccttgca gattgcaaaa
    19081 ggtgtggtca tctatgtaga aaaggaaagt gtaatgggaa agacaaaaga actgcttttt
    19141 aagtagttct ttttctggta atagataatg aaagaagaaa gaagacaatt ttttgaaaga
    19201 gtcgatggaa accaatgtcg tgattatatc ttgtcgcact gttcaaaaga ctatgagaaa
    19261 gtcaagcgtt cccttgaacg cttgatgaac aatcgtttta tgtttgatag tccttgggat
    19321 atggagcctt gttcaaaaat ctatcaaatc cagccgatgg tatgggatca agtatttgaa
    19381 gatgatccag aatgggctta tatgctcaat cgacaagaat atctcttgca gtttatgata
    19441 gggtatgtgg tagaaggaga taagagctat attcaaaagt gcaagttctt tctatttgat
    19501 tggattgagc aggtgagaga attttctcct caatctttga tgactagaac cttggatacg
    19561 ggtattcgtt cctttacttg gttgaaacta ctcttgctcc tcttgaaatt tgacttgcta
    19621 gaggagaaag aactagagaa aattttggtc agtctagaaa agcagattga ctttatgaaa
    19681 agctactatc gcgccaagta cacccttagt aactggggga ttttacaaac aattccgata
    19741 cttgctatct atcatttctt ttcagataag atggacctag aagaagctta tcattttgct
    19801 tcagaggagt tgaaacagca aattgagaca cagattttag gagatggaag ccagtttgaa
    19861 cagtcgattc tctatcatgt agaggtttat aaagccttgc tggatttgtg tctcttgctt
    19921 ccagacttgc aagatagtta ccaagagttg ctggaaaaga tggcgaccta tattcaaatg
    19981 atgacaggct tagatggacg gactttggct tttggtgata gcgattctac agaaacgaca
    20041 gaaatgttga gcctgtctgc tgtggttttg aacaaggaag accttcttaa cggtctggat
    20101 gttaaagttg atttgcttag cctcttgttc ctggggcgag aaaaggtcaa gcgactgcag
    20161 gaatttgaaa ggagagcttg gcagcctaag tccatgatct ttgaagactc tggacatgtc
    20221 tgtattaagg atgaacatcg ttatctattt ttcaaaaatg gtccgctagg aagcgcccat
    20281 agccatagtg acgagaatag tttttgctta cagtatcaag gccaacctat tttcatagat
    20341 gctgggcgtt attcttatcg ggagatatat gaacgttatc tcttaaagag tgcttggagt
    20401 cattcgacct gcattgtaga tgggaaagct ccggaaagaa tcacgggatc ctgggaatat
    20461 gaatactatc ctcactccct gttttgtcac cataaagaaa gggagggagt gcattatatt
    20521 gaaggggctt attggtcagc agaacctgat ttgccttatc ttcacaggag aaaaatcctc
    20581 atgttggtag aggatgtctg gctcttggta gatgacatca ggtgtcaagg tcaacatgag
    20641 gtgttgactc agtttatcct tgacaaggat gtgacctatc aagatgggaa aatcaatcag
    20701 ttgagactat ggagtgaagt tgattttgat ttggaagata ccatcatttc tcctaaatac
    20761 aatgagcttg aaagaagtag caaactcacc aagcgccaat tctttgagaa tcagatgctg
    20821 gattatacca tcattgcgca tgagagtttt gaaatcatcc gtcattctgt ctaccagaca
    20881 gatgatcgtg aagtggaaaa tgctctggct tttgaagtga aaaatgacga aacagacaag
    20941 ctgattctgt tattaagcga ggatatttgt gtaggtgaaa aattgtgcct cgttgacgga
    21001 acaaaaatgc gtggaaaatg tctagtatat gataaaataa atgagagaat gattcgcttg
    21061 cagtgctaga aataggcatt ttgaatagtg aatatgttat aataagtatt agtaggaggt
    21121 gttttagatt ggagaagaaa ctgaccataa aagacattgc ggaaatggct cagacctcga
    21181 aaacaaccgt gtcattttac ctaaacggga aatatgaaaa aatgtcccaa gagacacgtg
    21241 aaaagattga aaaagttatt catgaaacaa attacaaacc gagcattgtt gcgcgtagct
    21301 taaactccaa acgaacaaaa ttaatcggtg ttttgatcgg tgatattacc aacagtttct
    21361 caaaccaaat tgttaaggga attgaggata tcgccagcca gaatggctac caggtaatga
    21421 taggaaatag taattacagc caagagagtg aggaccggta tattgaaagc atgcttctct
    21481 tgggagtaga cggctttatt attcagccga cctctaattt ccgaaaatat tctcgtatca
    21541 tcgatgagaa aaagaagaaa atggtctttt ttgatagtca gctctatgaa caccggacta
    21601 gctgggttaa aaccaataac tatgatgccg tttatgacat gacccagtcc tgtatcgaaa
    21661 aaggttatga gcattttctc ttgattacag cggatacgag tcgtttgagt actcggattg
    21721 agcgggcaag tggttttgtg gatgctttaa cagatgctaa tatgcgtcac gccagtctaa
    21781 ccattgaaga taagcatacg aatttggaac aaattaagga atttttacaa aaagaaatcg
    21841 atcccgatga aaaaactctg gtatttatcc ctaactgttg ggccctacct ctagtcttta
    21901 ccgttatcaa agagttgaat tataacttgc cacaagttgg gttgattggt tttgacaata
    21961 cggagtggac ttgcttttct tctccaagtg tttcgacgct ggttcagccc tcctttgagg
    22021 aaggacaaca ggctacaaag attttgattg accagattga aggccgcaat caagaagaaa
    22081 ggcaacaagt cttggattgt agtgtgaatt ggaaagagtc gactttctaa aatgaaggaa
    22141 aatgacttgc aatctctgtt aagaaataaa ataatcccac ctagaacaag ctaggtggga
    22201 ttatttgcct atgaaatgag aaattatggg agcaagctcc taaatcaact gtttttgatc
    22261 tacttcttta actacttgat aaaagttata gaagtaggcc aaacttgaaa tgatggttac
    22321 gactaggaat attgaaaatt tccattggac agggttggtt aaaagttgtg gaaaggatat
    22381 gaggagaaag aagagggctg cgttgaggac aggtatccgt tttgattgta ttttctcaag
    22441 tcctttattg agcgcaggaa gaaagaggag taggagtagt aaaactgtat gagaaacagc
    22501 tcctgaaata agggcgaaga aaaggaaaat actgataaaa acatgaatga tcagtagtct
    22561 agctagtgat ttcataaggc acctcctaat cctggtcttt tttagctctt gcaatacgaa
    22621 gtgagtcgac aatatgtatc atcactccga aaaagaaagc tcccagcata gttttaaaaa
    22681 tatgttttgt atttagaaga gaactgataa aatttggatt ttcacttgtt agggtatcaa
    22741 tgagtggaat tataaaaaat atcactgttc cataaatcga acctgctttc agaccaggat
    22801 aacgtaactg tctcttttct tttttcatga gtttgctcct tttttaaaaa tcttccttcc
    22861 aaaagagact gttgaggtca gtttggaggc tgcgagcgag attgagacag agttccagag
    22921 ttggattgta cttgtcgttt tcaatcatat tgatggtctg tctcgagaca ccgatatcct
    22981 tggcgagctc gagctgggaa atgcccagtt ccttgcgaaa ttctttcaca cgattcatct
    23041 ggtctccttt ctgatttgtg tcgtatatat ttgactttat tatagtcttt taaacataaa
    23101 gtgtcaagta tttttgacat attttttgaa gaaatagtag tctccttgtc ctatttgtct
    23161 gacaagtgca agctggtcgg atttgtggta aaatagataa gatatgacaa aagaatttca
    23221 tcatgtaacg gtcttactcc acgaaacgat tgatatgctt gacgtaaaac ctgacggtat
    23281 ctacgttgat gcgactttgg gtggagcagg ccatagcgag tatttattaa gtaaattaag
    23341 tgaaaaaggc catctctatg cctttgacca ggatcagaat gccattgaca atgcgcaaaa
    23401 acgcttggca ccttacattg agaagggaat ggtgaccttt atcaaggaca acttccgtca
    23461 tttacaggca cgtttgcgcg aagctggtgt tcaggaaatt gatggaattt gttatgactt
    23521 gggagtgtct agtcctcaat tagaccagcg tgagcgtggt ttttcttata aaaaggatgc
    23581 gccactggac atgcggatga atcaggatgc tagtctgaca gcctatgaag tggtgaacaa
    23641 ttatgactat catgacttgg ttcgtatttt cttcaagtat ggagaggaca aattctctaa
    23701 acagattgcg cgtaagattg agcaagcgcg tgaagtgaag ccgattgaga caacgactga
    23761 gttagcagag attatcaagt tggtcaaacc tgccaaggaa ctcaagaaga aggggcatcc
    23821 tgctaagcag attttccagg ctattcgaat tgaagtcaat gatgaactgg gagcggcaga
    23881 tgagtctatc cagcaggcta tggatatgtt ggctctggat ggtagaatct cagtgattac
    23941 cttccattct ctagaagacc gcttgaccaa gcaattgttc aaggaagctt caacagttga
    24001 agttccaaaa ggcttgccct tcatcccaga tgatctcaag cccaagatgg aattggtatc
    24061 ccgtaagcca atcttgccaa gcgcagaaga attagaagcc aataaccgct cgcactcagc
    24121 caagttgcgc gtggccagaa aaattcataa gtaagaggga aaaagatggc agaaagaatg
    24181 gaaaaaacag gtcaaatact acagatgcaa cttaaacggt tttcgcgtgt ggaaaaagct
    24241 ttttattttt ccattgctgt aaccactctt attgtagcca ttagtattat ttttatgcaa
    24301 accaagctct tgcaagtgca gaatgatttg acaaaaatca atgcgcagat agaggaaaag
    24361 aagaccgaat tggacgatgc caagcaagag gtcaatgaac tattacgtgc agaacgtttg
    24421 aaagaaattg ccaattcaca cgatttgcaa ttaaacaatg aaaatattcg aatagcggag
    24481 taagatatga agtggacaaa aagagtaatc cgttatgcga cgaaaaatcg gaaatcgccg
    24541 gctgaaaaca gacgcagagt tggaaaaagt ctgagtttat tatctgtctt tgtttttgcc
    24601 gtttttttag tcaattttgc ggtcattatt gggacgggca ctcgctttgg aacagattta
    24661 gcgaaggaag ctaagaaggt ccatcaaacc acccgtacag ttcctgccaa acgtgggact
    24721 atttatgacc gaaatggagt cccgattgct gaggatgcga catcttataa tgtctatgcg
    24781 gtcattgatg agaactataa gtcagcaacg ggtaagattc tttacgtaga aaaaacacaa
    24841 tttaacaagg ttgcagaggt ctttcataag tatctggaca tggaagaatc ctatgtaaga
    24901 gagcaactct cgcaacctaa tctcaagcaa gtttcctttg gttcgaaggg caatgggatt
    24961 acctatgcca atatgatgac tatcaaaaaa gagttggaaa ctgcagaggt caaggggatt
    25021 gattttacaa ccagtcccaa tcgtagttac ccaaacggac aatttgcttc tagttttatc
    25081 ggcttagctc agctccatga aaatgaagat ggaagcaaga gcttgctggg aacctctgga
    25141 atggagagtt ccttgaacag tattcttgca gggacagacg gcattattac ctatgaaaag
    25201 gatcgtctgg gtaatattgt acccggaaca gaacaagttt cccaacaaac ggtagatggc
    25261 aaggatgttt acacaaccat ttccagcccc ctccagtcct ttatggaaac ccagatggat
    25321 gcttttcaag agaaggtaaa aggaaagtac acgacagcga ctttggtcag tgctaaaaca
    25381 ggggaaattc tggcaacaac gcaacgaccg acctttgatg cagatacaaa agaaggcatt
    25441 acagaggact ttgtttggcg tgatatcctt taccaaagta actatgagcc aggttcccct
    25501 atgaaagtga tgatgttggc tgctgctatt gataataata cctttccagg gggagaagtc
    25561 ttcaatagta gtgagttaaa aattgcagat gtcacgattc gagattggga cgtcaatgaa
    25621 ggattgactg gtggcagaat gatgaccttt tctcaagggt tcgctcactc aagtaacgtt
    25681 gggatgacgc ttcttgagca aaagatggga gatgctacat ggcttgatta tctaaatcgc
    25741 tttaaatttg gtgttccgac tcgttttggc ttgacggatg aatatgcagg ccaacttcca
    25801 gctgacaata tcgtaaatat tgctcagagt tcatttggac aagggatttc agcgacccag
    25861 acgcaaatga ttcgtgcttt cacggctatt gccaacgatg gagtcatgtt agaacctaaa
    25921 tttattagtg ccatttatga tccaaatgat caaactgctc ggaaatctca aaaagaaatt
    25981 gtgggaaatc ccgtttcgaa agatgcagct agccaaactc gtactcacat ggtcttggta
    26041 gggacggatc cggtttatgg aaccatgtat aaccacagca caggtaagcc aactgtaact
    26101 gttcctggtc aaaatgtagc cctcaagtcc ggtacggctc agattgccga tgagaaaaat
    26161 ggaggttact tagttggtac gaccaattac attttttcgg ctgtatcgat gaaccctgct
    26221 gaaaatcctg attttatcct ctatgtaacg gttcaacagc ctgagcatta ttcaggtatc
    26281 cagttgggag aatttgccaa cccaatcttg gagcgggctt cagctatgaa agaatctctc
    26341 aatcttcaat ctccagccaa gaatttagat aaagttacga cagaatcttc ttatgcaatg
    26401 cctagcatca aggatatttc acctggtgag ttggcggaag ccttacgtcg caatattgtg
    26461 caaccaatcg ttgtaggtac tggaacaaag attaaagaga cttctgtaga agaagggacc
    26521 aatcttgcac caaaccaaca agttctcctt ttatcggata aggtagaaga aattccagac
    26581 atgtatggct ggaaaaaaga gactgccgag acctttgcta aatggttgga tatcgagctg
    26641 gaatttgaag gttcaggttc cgtcgttcag aagcaggatg ttcggactaa tacagctatc
    26701 aaaaacatta aaaaaattaa attaacttta ggagactaat atgtttattt ctatcagtgc
    26761 tggaattgtg acatttttgc taactttagt aggaattcca gcctttatcc aattttatag
    26821 aaaggcgcaa attacaggcc agcagatgca tgaggatgtt aaacagcacc aggcaaaagc
    26881 tgggactcct accatgggag gtttggtttt cttaattgct tctgttttag ttgctttctt
    26941 tttcgcccta tttagtaatc aactcagcaa taatgttggt atgattttat ttatcttggt
    27001 tctttatggt ttaatcggat ttttagatga cttcctcaag gtcttccgta aaatcaatga
    27061 gggccttaat cccaaacaga aattggctct tcagcttcta ggtggcgtca ttttctacct
    27121 tttctatgag cgtggtggcg atatgctttc tgtctttggt tatcaagtac atctagggat
    27181 tttctatatt gtcttcgctc ttttctggct agtcggtttt tcaaacgcag tcaacttgac
    27241 agacggtatt gacggtctag ctagtatttc agttgtgatt agcttgtctg cctatggagt
    27301 tattgcctat gtgcaaggtc aaatggatat tcttctggtg attctagcca tgattggtgg
    27361 cttgctcggt ttcttcgtct ttaaccataa gcctgccaag gtctttatgg gggatgtggg
    27421 aagtttggct ctcggtggaa tgctggcagc tatctcgatg gccctccacc aagaatggac
    27481 tctcttgatt atcggaattg tttatgtctt tgaaacaact tcggttatga tgcaagtaag
    27541 ttatttcaaa atgacaggtg gcaaacgtat tttccgtatg acacctgtgc atcaccattt
    27601 tgagcttgga ggattgtctg gtaaaggaaa tccttggagc gagtggaagg ttgacttctt
    27661 cttttgggga gtgggacttc tagcaagtct cctgacccta gcaattttat atttgatgta
    27721 agaatggcac cctgatattt cagggtgttt ttgtgtttaa atacacaatg aaaatcaaag
    27781 aacaaactag aaagctaact ttaggctgct caaaatatag tagattgaaa ctagaatagt
    27841 acacatctac ttctaaaata ttgttagaaa tcgatttgac tgtcctgatt gatttgtcct
    27901 gttcttattt cgttttaata tacagttttg agatggttga tagaactgac gaagtcagct
    27961 caaaacacgg ttttgaggtt gtagataagg agaagctgat gtggtttgaa gaggttttcg
    28021 aagagtgtaa aaaaatattg gtcagtcaaa gtcaaaactc ttgacctttt ctgaccaatg
    28081 tagtatatta tgaacgtaag gtaaatgaaa gccttactag aacacttatt taaagtaaaa
    28141 tagaaagagg tgggtctatg tttcatctag aaatcttcag aagtaaagat agtctactcc
    28201 tgcttgaaaa agaaaaacca gaaatagtac gtagggtagc gatctagcta gtctaaattt
    28261 tttaaaacaa tggtcaaaga tagtcaatat cagtaatcat aactaagtaa acaaaaagag
    28321 gtaaagaata tgaataacaa ctttaataat tttaataaca tggatgattt atttaaccaa
    28381 ttgatgggtg gtatgcgagg atacagttct gaaaatcgcc gttacttaat taatggacgc
    28441 gaagtcacac ctgaggaatt tgctcactat cgtgcgactg gtcaattacc aggaaatgca
    28501 gaaactgatg tgcaaatgcc acaacaggca tcaggtatga aacaagacgg tgtccttgca
    28561 aaactaggtc gaaacttaac agcagaagcg cgtgagggca agttggatcc tgttatcgga
    28621 cgaaacaagg aaattcaaga aacatctgaa atcctctcac gccgcaccaa gaacaatcct
    28681 gttttggtcg gagatgcagg tgttggtaag acagcagttg tcgaaggtct agcgcaagcc
    28741 attgtgaacg gagatgttcc tgctgctatc aagaacaagg aaattatttc tattgatatc
    28801 tcaggtcttg aggctggtac tcaataccgt ggtagctttg aagaaaatgt ccaaaactta
    28861 gtcaatgaag tgaaagaagc agggaatatt atcctcttct ttgatgaaat tcaccaaatt
    28921 cttggtgctg gtagcactgg tggagacagt ggttctaaag gacttgcgga tattctcaag
    28981 ccagctctct ctcgtggaga attgacagtg attggggcaa caactcaaga cgaataccgt
    29041 aacaccatct tgaagaatgc tgctcttgct cgtcgtttca acgaagtgaa ggtcaatgct
    29101 ccttcggcag agaatacttt taaaattctt caaggaattc gtgacctcta tcaacaacac
    29161 cacaatgtca tcttgccaga cgaagtcttg aaagcagcgg tggattattc tgttcaatac
    29221 attcctcaac gtagcttgcc agataaggct attgaccttg tcgatgtaac ggctgctcac
    29281 ttggcggctc aacatccagt aacagatgtg catgctgttg aacgagaaat cgaaacggaa
    29341 aaagacaagc aagaaaaagc agttgaagca gaagattttg aagcagctct aaactataaa
    29401 acacgcattg cagaattgga aaagaaaatc gaaaaccaca cagaagatat gaaagtgact
    29461 gcaagtgtca acgatgtggc tgaatctgtg gaacgaatga caggtatccc agtatcgcaa
    29521 atgggagctt cagatatcga acgtttgaaa gatatggccc atcgcttgca agacaaggtg
    29581 attggtcaag ataaggccgt agaagctgta gctcgtgcta tccgtcgtaa ccgtgctggt
    29641 tttgatgaag gaaatcgccc aatcggcagc ttcctctttg tagggtctac tggggttggt
    29701 aagacggagc ttgctaagca attggcactc gatatgtttg gaacccagga tgcgattatc
    29761 cgtttggata tgtctgaata cagtgaccgt acaactgttt ctaagctaat tggtacaaca
    29821 gcaggctatg tgggttatga tgacaatagc aataccttaa cagaacgtgt tcgtcgcaat
    29881 ccatactcta tcattctctt ggatgaaatt gaaaaggctg atcctcaagt tattaccctt
    29941 ctcctccaag ttctagatga tggtcgtttg acagatggtc aaggaaatac agtaaacttc
    30001 aagaacactg tcattattgc gacctcaaat gctggatttg gctatgaagc caacttgaca
    30061 gaagatgcgg ataaaccaga attgatggac cgtttgaaac ccttcttccg tccagaattc
    30121 ctcaaccgct ttaatgcagt catcgagttc tcgcacttga ctaaggaaga cctttctaag
    30181 attgtagatt tgatgttggc tgaagttaac caaaccttgg ctaagaaaga cattgacttg
    30241 gtagttagtc aagcggctaa agattatatc acagaagaag gttacgacga agtcatgggg
    30301 gttcgtcctc tccgtcgcgt ggttgaacaa gaaattcgtg ataaggtgac agacttccac
    30361 ttagatcatt tagatgctaa acatctggaa gcagatatgg aagatggcgt tttggttatt
    30421 cgtgagaaag cctaagatag aattttgagg ataaaaaaga aggagccagc tgaaaaaaac
    30481 tggttccttt ttaggtacga caggcatgtc gtatagtaga agtgtattat tccagtttca
    30541 atatactata gtagctcaga agtcggtact taaacgtgct atatcaaaac cagtccttga
    30601 aaaacgtgga ctggtttcgt gtttggatta ttaccttgaa cgacatgcgt taaaagttag
    30661 ttgaaccgcc gtatgccgaa cggcacgtac ggtggtgtga gaggggctag agattatccc
    30721 ctactcgatt ttaaatcaca tgacgttcaa aggcatcatc tgaaatccct tgttccaaga
    30781 tgagttttgc ccattcttta gcagagaaga ggctgtggtc cttgtagttt ccgcaagatt
    30841 cgatggttgt ccctgggaca tcttcccaag tagtagtttc agcgatttcc ttgagcgaat
    30901 ccttgataac agctgcaatt ttagcactgg tgtgacgtcc ccacataatc atgtggaagc
    30961 ctgtgcggca accaaatggc gaacagtcaa tcatgccgtc aatgcgggta cggatgagtt
    31021 tggctaagag gtgctcgata gtgtgaaggc cggcggtagg gatggagtct tcgtttggtt
    31081 gcaccaagcg aatatcataa ttggagatga tgtctccttt tggtcctgtt tcttccccaa
    31141 tcaagcgaac atagggtgct ttgacaatgg tgtggtcaag ttcaaaactt tcgacaataa
    31201 cttcttttga catggtaaat cctttcagtt ttcttctctc attatatcat aaaggttgct
    31261 cctgagacag agagaaaacc tctccgaggc tggagaggtt gaaatcttta cttacgatat
    31321 aagcggtcgt attggtagta tgggtcaaag gttacgttga tacccagttt acgaaggaca
    31381 ttcttgtctt catcagtcaa gatgatggtt gagtgggctt cgcttccttt gaggttgccg
    31441 agttcttcca tagcgcgggc agcatcagga ttttctgtag ctgtgatagc aagtgcaatc
    31501 aggatttcat ttgaatgaag gcgtggattg cggctaccga gatgatcgat tttaagacct
    31561 tggattggct taacaacttc cggctcgatt aattttactt ctttagcgat gtcagctgat
    31621 tttttgatgg cgttgatcaa ggcagcggct gtaggcccaa agagttctga gttcttacca
    31681 gtgacgattt ccccatttgg caattcaaag gctagggctg gtccaccagt ttcttctgct
    31741 ttttggcgcg caacgacagc aaccttacgg tctgcaggtg tgataccgag gtcgttcatg
    31801 agcaactcaa ttttcttgac ggcagcttcg ccaacttttt cagctttgaa gtcaagaact
    31861 gtttgatagt aacggcggat gatttcttgt ttagaagctt cgacagcagc ctcgtcatct
    31921 gtaatagcga aaccaaccat gttgacaccc atatctgtcg gtgaagcgta tggtgatttt
    31981 ccgagaatac gttccaacat gcgcttgagc actgggaaga tttcgatatc acggttgtag
    32041 ttgacagtgg tttctccata ggtttgaaga tggaaggggt caatcatgtt gacatcatca
    32101 aggtcagctg tggcagcttc ataagccaag ttaactggat gatgaagggg aagattccaa
    32161 acagggaagg tttcaaattt agcgtagcca gatttgatgc cattgatttg gtcgtgatac
    32221 atattggaca tacacgttgc caattttcca gaaccaggtc caggagcggt tacgacaatc
    32281 aagttgcgac tggttttgat gtagtcgttt ttgcccatgc cttctgggga aatgatgtga
    32341 tccatatccg tcggatatcc tttgattgga taatgaagat aagaatcaat tccgtttttc
    32401 tcaagttggt tgcggaaggc atctgcagcg ggttggccag cgtattgtgt aatgacaacg
    32461 gaaccaacaa aaatccctaa ttcattgaat ttgtcaatca aacgaagaac ttcttggtca
    32521 taagaaatgc ctaagtcgcc acgtgctttg gaatgttcaa tgttgctagc attaatggca
    32581 atcacaacct caacctgctc tttcaattct tgcaagagct tgattttgtt gtcaggttca
    32641 taaccaggaa ggacacgagc agcgtggaaa tcttctaaca ttttaccgcc aaactctaag
    32701 tagagcttgc cgtcaaattg gttaatgcgc tccaaaatat ggtcgcgttg taaattcaaa
    32761 tattgttcag aactaaaagc ttgttttttc atttttttac ctctggactc tattataata
    32821 aaaaattgga agttaggaaa ctacggagct aaaaaagaaa ttaaaaagat taagcaaacg
    32881 cttgcacaaa attttaaaaa gtgctatcat agactataga ttatgaaaat aatgaggtaa
    32941 acagatgcaa gaaaaatggt ggcataatgc cgtagtctat caagtctatc caaagagttt
    33001 tatggatagt aatggagatg gaattggcga tttgccagga attaccagta agttggacta
    33061 tctagccaag ctaggaatca cagcaatttg gctttctccc gtttatgaca gccctatgga
    33121 tgataatggc tacgatattg ctgattatca agcgattgca acgatttttg gaaccatgga
    33181 ggatatggat caactgattg cagaagctaa gaagcgtgat atccgtatca tcatggactt
    33241 ggtggtcaat catacctcgg atgagcatgc ctggtttgta gaggcctgtg aaaatcctaa
    33301 tagccctgag cgagactact atatctggcg cgatgaaccc aatgacctag attctatctt
    33361 tagtgggtct gcttgggaat acgatgaaaa gtcaggtcaa tactatctcc actttttcag
    33421 caagaaacag ccggatctca actgggaaaa tgaaaaactt cgccagaaaa tttatgagat
    33481 gatgaacttc tggattgata aaggtattgg tggtttccgt atggatgtta ttgacatgat
    33541 tggcaaaatt cctgacgaga aggtagtcaa taatggtcct atgctccatc cctatctcaa
    33601 ggaaatgaat caggcgacct ttggagataa ggatttcttg acagtagggg agacttgggg
    33661 agcaacgcca gagattgcca agctctactc tgatccaaag gggcaagaat tgtctatggt
    33721 cttccagttt gaacatatcg gtcttcagta tcaggaaggt cagcctaaat ggcactatca
    33781 aaaagagctg aatatcgcta agttaaaaga aatcttcaac aaatggcaga cagagttagg
    33841 agttgaggac ggctggaatt ccctcttctg gaacaaccat gacctccctc gtattgtctc
    33901 aatctgggga aatgaccaag aataccgcga aaaatctgcc aaagcctttg caatcttact
    33961 tcatctcatg agaggaactc cttatatcta ccaaggtgag gagattggga tgaccaacta
    34021 tccgtttgaa acactggatc aagtagaaga tattgaatct ctcaactatg cgcgtgaggc
    34081 tcttgaaaaa ggtgttccga ttgaagaaat catggacagt atccgtgtta ttggacgtga
    34141 caatgcccgt acccctatgc aatgggacga gagcaaaaac gctggtttct caacaggtca
    34201 accttggttg gcggttaatc caaactacga agaaatcaac gttcaagaag cactggcaaa
    34261 ctcagattct attttctata cctatcagaa actcatccag attcgtaagg aaaacagctg
    34321 gttgattcga gctgatttta aattactcga tacggctgat aaggtctttg cttatatccg
    34381 taaggacggt gaccgtcgct tcctagtcgt ggctaattta tccaatgata aacaaaactt
    34441 ttcagtagat ggaaaagtta gatctgtctt gattgaaaac actgcggcta aagaagtact
    34501 tgaaaaacag gtcttgactc catgggatgc tttctgtgtg gaaatgactg actagaatga
    34561 gcaagagcct gggacaaaat agttctcgac cacaaaaaag ctagagattt ccaattgtgg
    34621 aactctagct ttttaatttt gagtcattct cttattgtat tttaggaggt tattggccat
    34681 aagtaccaat cccatgtcaa ttctcacttg acgcttgccc ctcagattac atctcttgta
    34741 acccaaacaa gcctttatct gcccaaagac aggttccaca tcaatcttgc gttgagcgaa
    34801 aatctgtcta ccttggggag ataaaagcgc ctgacattct ttagctttca agttttgata
    34861 gccttcgttc atatacagtc cccttttgag gggctgattc aggttcgtcg acgtagtaaa
    34921 ccttgatttc ttgttgaaag tctgtctgtg ttttctgatg tttggtatgg tgaaaacgat
    34981 aatactagcc atcaggatgt gtatagctat cctccttgtc attatagtgc caattcgcta
    35041 agtttctagc tgactgttta tagcctctct tctgttcctt atcaaacatg gcatatttaa
    35101 tcagatggtt tacctccttt tcatctaaac gaaggaggtt ctcttcactt ccatatccag
    35161 catctgcgac aactgtcttc aagtcatgcg gataggtttc aaggaatggc agaagagtct
    35221 tggtatctgt cggatttgaa aagacatcat agtgaagaac aaattggttt tccgtagcga
    35281 tttgaagatt ataagcagcc ttgggttgac tatttttcat atgttcttcc ttcatccgca
    35341 taaaagtggc atctggatcg gttttggaaa aactgttagg cccttgaaat gtctcctgat
    35401 agttctcata tttttcagca cgtactgaaa aatcctcctt taaactcttc ataatccttt
    35461 ttatttttat gaagatattg tttgaaagat gtgagtttcc acggatgggt ttgtggaggg
    35521 atatacttgc gtctttcttt ttttgttctg gttcttgttc aaggtttttc gaatagagtt
    35581 catgatttag tagctccttt gtgtgataga ttttgtcagc gatattgagg tagatgtcac
    35641 catcaaatgc ttttataact aatgcttttg tctttctgat gaaatagact tcttttcctt
    35701 gctcggtagg gatatagcaa cgattttgga atcggatatg gtgtccacta tcgacgactc
    35761 tctcccgcca gtttagctag aatgagattt cgttcagagg gcttaggagc ctcctcaaag
    35821 acagagagtt ttgtcttgtt tccaaactgt tcattaaagg tttggatata ggaaggcaga
    35881 aaggtattgg cttcttccaa ggtatgaatc ttgtttcgtt ccagttcgat aggcaggaga
    35941 gattgtagta tctgattgag tctttcgact ctccctttag cttgagggat agaggttgtc
    36001 tcaaggagaa ttcccagttg gtgacaggcg tatccaaatt gtgtatgggt gtcgtcctcc
    36061 attttcttag agttggaggc ttgataggta aaaacagttc tcttatctgt tttgatttga
    36121 acaggaatgc cgtggttggc taagatttgt tcgaggacat gatagtaagc attcaaggtc
    36181 tcttgtttgt caaaataagc gcctaggata ttgccagaag catcatcaat ggctaggtgt
    36241 aagttagagg tttctgctcc aaaccaggca tgagggctgg catccatttg gatgagttct
    36301 ccagcaaatt tctttctggg tctactagga tgtacctttt tagggtcttc caggaagttt
    36361 tcagccgtcg gtaagattgg attgtctagg ggttgcttgg ggttcagttt agcttgcttt
    36421 cttactctct tctttgtctt tctatgggac ttaggcgaca ggatattttt cttatagagt
    36481 atttttctaa cagttgtatc agagagctga attccttctt cttcagctag caattcacag
    36541 aaatgacgga catttggttt atatgtttca taggagaggt atttctttag gatacgttct
    36601 ttgatttcat cagggattgc atgttttggt tttcgatttc tgtttccgtg tctgaaggct
    36661 tcttttcctt tctgttgata ggctagtagc agacgattga tttgcctttc agaaagattg
    36721 agctcgacac aggctcgttt ctttgttttc tttccttggg ctatagcttt tatcacaaga
    36781 tattttttcg tttcattcat attcagttgg atcctttaca tatgactatt ctaccaaatg
    36841 ggacattttt acgttcgatt tactaaagac attatcacat tcgaattaca caagatgcag
    36901 atagtgaaaa aaaggtgtag acattaccgt aaaaaagtga tataattgta agatgttcaa
    36961 tgtataggtg ttaatcatga gtagacgttt taaaaaatca ggttcacaga aagtgaagcg
    37021 aagtgttaat atagttttgt tgactattta tttattgtta gtttgttttt tattgttctt
    37081 aatctttaag tacaatatcc ttgcttttag atattttaat ctagtggtaa ctgcgttagt
    37141 cctactagtt gccttggtag ggctactctt gattatccat aaaaaagctg caaagtttac
    37201 tatttttctg ttggtgctct ctattcttgt cagctctgtg tcgctctttg cagtacagca
    37261 gtttgtggga ctgaccaatc gtttaaatgc gacttctaat tactcagaat attcgatcag
    37321 tgtcgctgtt ttagcagata gtgagattga gaatgttacg caactgacga gtgtgacagc
    37381 accgactggg actgataatg aaaacattca aaaactacta gctgatatca aatcaagtca
    37441 gaatatcgat ttgacggtca atcaaagttc gtcttacttg gcaacttaca agagtttgat
    37501 tgcaggagag actaaggcca ttgtcttaaa tagtgtcttt gaaaatatca tcgaatcgga
    37561 gtatccagat tacgcatcga agataaaaaa gatttatacc aagggattca ctaaaaaagt
    37621 agaagctcct aagacgtcta agaatcagtc tttcaatatc tatgttagtg gaattgatac
    37681 ttatggtccg attagttcgg tgtcgcgttc agatgtcaat atcctgatga ctgtcaatcg
    37741 agataccaag aaaattctct tgaccacaac gccacgtgat gcttatgtac caatcgcaga
    37801 tggtgggaat aatcaaaaag ataaattgac ccatgcgggc atctatggag ttgattcgtc
    37861 cattcacacc ttagaaaatc tctatggagt ggatatccat tactatgtcc gtttgaactt
    37921 cacttctttc ttgaaattga tcgatttgtt gggtggggta gatgtttata atgaccaaga
    37981 tttcacatct ctacacggga agttccattt cccagttgga aatgtccact tagattctga
    38041 gcaggctctg ggatttgttc gtgagcgcta ttccctagcg gatggtgatc atgaccgcgg
    38101 gcgcaatcaa caaaaggtga ttgcggctat ccttcaaaaa ttaacttcga gcgaagcgct
    38161 gaaaaattat agtatgatca ttgatagctt gcaagattct atccaaacaa acatgcccct
    38221 tgagaccatg ataaacttgg tcaatgctca gttagaaagt ggtggaacgt acaaagtaaa
    38281 ttcgcaagac ttgaagggta ggggacggac ggatcttcct tcctatgcga tgccagatag
    38341 taacctctat atgatggaaa ttaacgacag tagccttgca tctgtcaaaa ctgctattca
    38401 ggatgtgttg gagggcagat gaaatgattg atattcattc gcacattgtc tttgatgtag
    38461 atgatggtcc caagtcaaga gaggaaagta aggctctctt gacagaagcc tacaggcagg
    38521 gggtgcgaac cattgtctct acctctcacc gtcgcaaggg catgtttgaa actccagaag
    38581 agaagatagc agaaaacttt cttcaggttc gggaaatagc taaggaagtc gcgagtgact
    38641 tggtcattgc ttatggggcc gaaatttact acacaccaga tgttttgggt aagctggaaa
    38701 aaaatcggat tccgaccctc aataatagtc gttatgcctt gatagagttt agtatgaaca
    38761 ccccttatcg cgatattcat agtgccttga ttaaaatatt gatgttggga attactccag
    38821 tcattgccca catcgagcgc tatgatgctc ttgaaaataa tgaaaaacgc gttcgagagc
    38881 tgattaatat gggctgttac acgcaagtaa atagttcaca tgtcctcaaa tccaaacttt
    38941 ttggagaacc ttataaattc atgaaaaaaa gagctcagta tttcttggag cgtgatttgg
    39001 ttcatgtgat tgcaagtgat atgcataatg tggacagcag acctccccat atggcagaag
    39061 catatgacct tgtttcccaa aaatacggag aaacgaaggc tcaggacctt tttatagaca
    39121 atcctcgaaa aattgtaatg gatcaactaa tttaggagaa ataatgaaag aacaaaacac
    39181 gatagaaatc gatgtatttc aattacttaa aaccttgtgg aaacacaagc taatcatttt
    39241 attagtggca cttgtgacag gggcgggagc ttttgcatat agcattttta ttgttaagcc
    39301 agaatataca agcaccacgc gtatttacgt agtcaatcgt aatcaagaaa ataagccggg
    39361 actgacgaat caggacttgc aggcaggaac ttatctggta aaagactacc acgaaattat
    39421 cctttcgcaa gatgtattgg aaaaggtagc gacaaatttg aaattggata ttccagtaaa
    39481 aacgttaact agcaaagtgc aagtgactgt accagccgac actcgtatcg tctcaatctc
    39541 tgtcaaggat aaacaaccag aggaagccag tcgcattgct aattctatac gagaagttgc
    39601 tgcagaaaag atcatcgctg taacgcgagt atctgatgta acgacgcttg aagaagcgcg
    39661 accagctacg actccctctt ctccaaatgt tcgacgcaac accttagttg gttttcttgg
    39721 agccgccgcc gtaacagtaa ttactgttct tttgattgag ttgttcgata cccgtgtaaa
    39781 acgtcctgaa gaagttgaag atgtactgca aatgccactt ctaggagtcg ttccagattt
    39841 taataaaatg aaataggagg aagttatgcc aacgttagaa atctcacagg cgaaattaga
    39901 acttgcgaaa aagacagagg aatattataa tgctttgtgc acgaacctac agttaagtgg
    39961 agatgatttg aaagtatttt ctatcagttc tgtgaaagca ggagaaggaa aaacaacgac
    40021 ttccaccaat atcgcttggg cttttgcgca tgcaggttac aaaacgctgc tgattgatgc
    40081 agacatgcgt aactccgtta tgtcaggtgt ctttaaatca agggaaagga ttactgggct
    40141 aacagaattt ctatcaggga caacagacct gtcacagggg ctttgcgata ccaatgttga
    40201 gaatctcttt gtgattcagg ctggctctgt gtcaccaaat ccgatagccc ttcttcaaag
    40261 taagaatttc agtacaatgc ttggaacctt gcgtaaatat tttgactata tcgtcgtaga
    40321 cactgctcct atcggtatcg tgattgatgc ggctatcatt atgcagaaat gtgatgcttc
    40381 tattttagtg acgaaggcag gtgaaacaaa acgacgggaa cttcaaaaag cgaaagaaca
    40441 gttggaacaa actgggaagt cgtgtttagg agttgtgttg aataaattcg atacttcagt
    40501 agacaaatac ggtttttatg ggagttatgg gagttacagg aaacagaaaa aataggttga
    40561 gggatagaga tgaatgaaaa actagcaaag tcttcagtag ctatagtcca gagttttctt
    40621 gttattttat tgacttatct acttagcgct gtgagagaaa cagagattgt ttcaacaaca
    40681 gctattgtac tttatatcct ccactatttt gtcttttata tcagtgatta tggacggaat
    40741 ttctttaaaa ggagatattt gattgaactt gtccagacat tgaaatatat cctattcttt
    40801 gcgctagcga ttagtatttc taattttttc ttagaggatc gatttagtat ttccagacga
    40861 ggcatgattt acttcctcct attacatgtt ttcttagtct atatgctaaa cctatttatc
    40921 aagtggtatt ggaagcgggc ttatcccaac tttaaaggaa gtaagaaggt tttcctactt
    40981 acagcaactt ctcatgtcga aaaggtactg gatagactaa tagaatcaga tgatgttgtt
    41041 ggggagttgg tagccgtcag tgttttagat aaaccagatt ttcagcatga tgatttaaag
    41101 gttgtagcag agggggagat cgtaaacttt gcgactcgtg aggtggtcga tgaagtcttt
    41161 atcaatcttc caagtgaaaa atacaatatt ggagagcttg tctctcagtt tgaaacgatg
    41221 ggaattgatg taacagtcaa tctaaatgct ttcgattggg cacgtaacaa gcaaatttgt
    41281 gagatggcag gactaaatgt tgtgactttt tctacaacat tttataagac tagccatgtg
    41341 attgctaagc gggttattga tattatcggt tccctggtag gtttgatact atgtggtcta
    41401 gtcagtattg tgctggttcc tttgattcga aaggatgggg gctctgctat ttttgctcag
    41461 acgcgtatag gaaaaaatgg ccgccatttc actttttaca agtttcgctc tatgtgtgta
    41521 gatgctgagg ataaaaagag agaactcatg gaacaaaata ccatgcaggg tggaatgttt
    41581 aaggtggacg atgatcctcg tatcacgaaa attggtcatt ttatacggaa gacgagcttg
    41641 gacgagctac cacagtttta taatgttcta aagggagata tgagtttggt aggtacacga
    41701 ccaccaacag tggacgagta tgaacactat accccagaac aaaaacgtcg gctaagtttt
    41761 aaacctggta taacaggctt atggcaggtc agtggacgaa gtgaaatcaa aaatttcgat
    41821 gaagttgtca aattagatgt ggtctatatt gatggttgga caatctggaa agatattgaa
    41881 attttattga agacagttaa agttgtattg atgaaggatg gagcgaaata gtttgctttt
    41941 gtttcagact attaggagaa aaatgaagaa gtcagtttat atcattggtt caaaagggat
    42001 tcccgctaag tatgggggct ttgaaacctt tgttgagaaa ttaacagaat atcaaaaaga
    42061 tggtaacatc caatactatg ttgcctgcat gcgcgaaaat tctgcaaaat caggatttac
    42121 agcagataca tttgagtaca atgatgctat ttgttacaac attgatgtgc ctaatattgg
    42181 tcctgctaga gccattgctt atgatattgc tgctgtgaat aaagcgattg aaatagctaa
    42241 gaaaaacaaa gatgaagctc ctatttttta cattctagct tgtcgtatcg ggccttttat
    42301 agctagactt aagaaaaaga ttcaagctat cggaggtact ctgtttgtca atccagatgg
    42361 acatgagtgg cttcgggcta aatggagcct gccggttcga aagtattgga aattttcgga
    42421 acagttgatg gtcaaatatg cagatttatt ggtctgtgat agcaaaaata ttgaaaaata
    42481 tatccagaat gactataagc aatatcaacc aaagacgact tatattgctt acgggacgga
    42541 tacaagtccg tctatcctga aatccgaaga tctaaaaatt cgtagttggt atcaggaaaa
    42601 aggacttagc gaaaatggct attatctagt ggtgggacga ttcgtccctg aaaacaacta
    42661 cgaaaccatg attcgtgaat ttatcaaatc taagtccaag aaggactttg tcctcatcac
    42721 aaatgtggag cagaataaat tttacgacca gttgttacag gagactggtt ttgacaaaga
    42781 tcctagggtt aaatttgtag gtactgtcta tgaccaagaa ttgcttaagt acattcgtga
    42841 aaatgctttt gcctatttcc atgggcatga ggttggaggg accaaccctt ctctactaga
    42901 agctctagca tccacaaaac tgaatttgtt gctagatgtt ggttttaacc gtgaggttgg
    42961 tgaagacggg gctatttatt ggagaaaaga taatcttcat aaggttattg aagagagtga
    43021 acaaaaaaca atagaagaaa taaaagaaat agatattcta tctacagagc aggtagaaaa
    43081 aagatttact tgggatttta ttgttaatga atatgaaaat ttatttttac tagggaaata
    43141 attatctaag ttacaaggat tttatttgag gaa
//
LOCUS       DAVLXH010000012        42672 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00028199
            SAMN33607166-rid17955573.denovo.012, whole genome shotgun sequence.
ACCESSION   DAVLXH010000012 DAVLXH010000000
VERSION     DAVLXH010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607166
            Sequence Read Archive: SRR23725544
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 42672)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42672)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721421.1
            Genome Coverage       :: 115x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:42:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,210
            CDSs (total)                      :: 2,161
            Genes (coding)                    :: 2,023
            CDSs (with protein)               :: 2,023
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 73 of 138
            Pseudo Genes (incomplete)         :: 60 of 138
            Pseudo Genes (internal stop)      :: 40 of 138
            Pseudo Genes (multiple problems)  :: 31 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42672
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607166-rid17955573.denovo.012"
                     /strain="AUSMDU00028199"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1349"
     gene            <1..156
                     /locus_tag="VYO11_000727"
     CDS             <1..156
                     /locus_tag="VYO11_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV1595322.1"
                     /translation="LLFFIINNSSSSQTNILAQLMDFFTGNGHLEDLSKISEPEKLYA
                     YIAEATA"
     gene            194..499
                     /locus_tag="VYO11_000728"
     CDS             194..499
                     /locus_tag="VYO11_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV1595323.1"
                     /translation="MIKILAACGAGVNSSHQIKSALEEELSNRGYDVHCDAVMVKDVN
                     EDLMKGYDIFTPIAATDLGFEPGIPVIEAGPILFRIPAMSAPVFDNIEAAIKEHGLS"
     gene            547..2022
                     /locus_tag="VYO11_000729"
     CDS             547..2022
                     /locus_tag="VYO11_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HEV1595324.1"
                     /translation="MDAIFDLIGKVFNPILEMGGPVIMLIILTVLALLFGVKFSKALE
                     GGIKLAIALTGIGAIIGMLNGAFSASLAKFVENTGIQLSITDVGWAPLATITWGSAWT
                     LYFLLIMLIVNVVMLAMKKTDTLDVDIFDIWHLSITGLLIKWYADNNGVSQGVSLFIA
                     TAAIVLVGVLKIINSDLMKPTFDDLLNAPSSSPMTSTHMNYMMNPVIMVLDKIFEKFF
                     PGLDKYDFDAAKLNKKIGFWGSKFFIGFILGIVIGIMGTPHPIAGVADADKWRLVIKG
                     WLSLGLTAGVSLELFSLIGSWFIAAVEPLSQGITNVATKRLQGRKFNIGLDWPFIAGR
                     AEIWACANVLAPIMLIEAVLLSKVGNGILPLAGIIAMGVTPALLVVTRGKLLRMIIFG
                     TLLLPLFLLSGTLIAPFATELAKGVGAFPEGVSQTQLITHSTLEGPIEKLLGWTIGNT
                     TTGDIKAILGAVAFLVFYIGIFAWYRKQMIKRNEEYAAKAK"
     gene            2282..8983
                     /locus_tag="VYO11_000730"
     CDS             2282..8983
                     /locus_tag="VYO11_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ig-like domain-containing protein"
                     /protein_id="HEV1595325.1"
                     /translation="MGKGHWNRKRVYSIRKFAVGACSVMIGTCAVLLGGNIAGESVVY
                     ADETLITHTAEKPKEEKMIVEEKADKALETKNVVERTEQSEPSSTEAIASEKKEDEAV
                     TPKEEKVSAKPEEKAPRIESQASSQEKPLKEDAKAVTNEEVNQMIEDRKVDFNQNWYF
                     KLNANSKEAIKPDADVSTWKKLDLPYDWSIFNDFDHESPAQNEGGQLNGGEAWYRKTF
                     KLDEKDLKKNVRLTFDGVYMDSQVYVNGQLVGHYPNGYNQFSYDITKYLHKDGRENVI
                     AVHAVNKQPSSRWYSGSGIYRDVTLQVTDKVHVEKNGTTILTPKLEEQQHGKVETHVT
                     SKIVNTDDKDHELVAEYQIVERGGHAVTGLVRTASRTLKAHESTSLDAILEVERPKLW
                     TVLNDKPALYELITRVYRDGQLVDAKKDLFGYRYYHWTPNEGFSLNGERIKFHGVSLH
                     HDHGALGAEENYKAEYRRLKQMKEMGVNSIRTTHNPASEQTLQIAAELGLLVQEEAFD
                     TWYGGKKPYDYGRFFEKDATHPEARKGEKWSDFDLRTMVERGKNNPAIFMWSIGNEIG
                     EANGDAHSLATVKRLVKVIKDVDKTRYVTMGADKFRFGNGSGGHEKIADELDAVGFNY
                     SEDNYKALRAKHPKWLIYGSETSSATRTRGSYYRPERELKHSNGPERNYEQSDYGNDR
                     VGWGKIATASWTFDRDNAGYAGQFIWTGTDYIGEPTPWHNQNQTPVKSSYFGIVDTAG
                     IPKHDFYLYQSQWVSVKKKPMVHLLPHWNWENKELASKVADSEGKIPVRAYSNASSVE
                     LFLNGKSLGLKTFNKKQTSDGRTYQEGANANELYLEWKVAYQPGTLEAIARDESGKEI
                     ARDKITTAGKPAAVRLIKEDHAIAADGKDLTYIYYEIVDSQGNVVPTANNLVRFQLHG
                     QGQLVGVDNGEQASRERYKAQADGSWIRKAFNGKGVAIVKSTEQAGKFTLTAHSDLLK
                     SNQVTVFTGKKEGQEKTVLGTEVPKVQTIIGEAPEMPTTVPFVYSDGSRAERPVTWSS
                     VDVSKPGIVTVKGMADGREVEARVEVIALKSELSVVKRIAPNTDLNSVDKSVSYVLTD
                     GSVQEYEVDSWEITEVDKAKLSVAGSRIQMTGQLAGETIHATLVVEEGNAAAPVVPTV
                     TVGGEAVTGLTSRQPMQYRTLSYGAQLPEVTASAENADVTVLQASAANGMRASIFVQP
                     KDGGPLQTYAIQFLEEAPKIAHLSLQVEKADSLKEDQTVKLSVRAHYQDGTQAVLPAD
                     KVTFSTSGEGEVAIRKGMLELHKPGAVTLNAEYEGATGQITLTIQANTEKKIAQSIRP
                     VNVVTDLHQEPSLPATVTVEYDKGFPKAHKVTWQAIPKEKLDSYQTFEVLGKVEGIDL
                     EARAKVSVEGIVSVEEVSVTTPIAEAPQLPESVRTYDSNGHVSSAKVAWDAIRPEQYA
                     KEGVFTVNGRLEGTQLTTKLHVRVSAQTEQGANISDQWTGSELPLAFASDSNPSDPVS
                     NVNDKLISYNNQPANRWTNWNRTNPEASVGVLFGDSGILSKRSVDNLSVGFHEDHGVG
                     APKSYVIEYYVGKTVPTAPKNPSFVGNEDHVFNDSANWKPVTNLKAPAQLKAGEMNHF
                     SFDKVETYAVRIRMVRADNKLGTSITEVQIFAKQVAAAKQGQTRIQVDGKDLANFNPD
                     LTDYYLESVDGKVTAVTASVSNNGLATVVPSVREGEPVRVIAKAENGDILGEYRLHFT
                     KDKNLLSHKPVAAVKQARLLQVGQALELPTKVPVYFTGKDGYETKDLSVEWEEVPAEN
                     LTKAGQFTVRGHVLGSDLVAEVTVRVTDKLGEALSDNPNYDENSNQAFASATNDIDKN
                     SHDRVDYLNDGDHSENRRWTNWSPTPSSNPEVSAGVIFRENGKIVERTVAQAKLHFFA
                     DSGTDAPSKLVLERYVGPGFEVPTYYSNYQAYESGHPFNNPENWEAVPYRADKDIAAG
                     DEINVTFKAVKAKAMRWRMERKADKSGVAMIEMTFLAPSELPQESTQSKILVDGKELA
                     DFAENRQDYQITYKGQRPKVSVEENNQVASTVVDSGDDSLPVLVRLVSESGKQVKEYR
                     IHLTKEKPVSEKTVATVQEDLPKLEFVEKDLAYKTVEKKDSTLYLGETRVEQEGKVGK
                     ERIFTAINPDGSKEEKLREVVEAPTDRIVLVGTKPVAQEAKKPQVSEKADTKPIDSSE
                     ASQTNKAQLPNTGSAASQAAVAAGLALLGLSAGLVVTKGKKED"
     gene            complement(9230..10086)
                     /locus_tag="VYO11_000731"
                     /pseudo
     CDS             complement(9230..10086)
                     /locus_tag="VYO11_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014125496.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(10298..10657)
                     /locus_tag="VYO11_000732"
     CDS             complement(10298..10657)
                     /locus_tag="VYO11_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HEV1595326.1"
                     /translation="MGMILMKLASILLLILTLVVCIILTKLFRLKKLGRNFADLAFPV
                     LVFEYYLITAKTFTHNFLPRLGLALSFLAIILVFFFLLKKRSFYYPKFIKFFWRAGFL
                     LTLIMYIEMIVELFLMK"
     gene            10749..11705
                     /locus_tag="VYO11_000733"
                     /pseudo
     CDS             10749..11705
                     /locus_tag="VYO11_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002881980.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein.; internal stop;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
     gene            11689..12246
                     /locus_tag="VYO11_000734"
     CDS             11689..12246
                     /locus_tag="VYO11_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEV1595327.1"
                     /translation="MKRPLEMAHDFLAEVVTKEDVVVDATMGNGHDTLFLAKLAKQVY
                     AFDIQKQALEKTQERLHQADLTNAQLILQGHETLDQFVIKAKAGIFNLGYLPSADKSV
                     ITRPQTTIEALEKLCGLLVKGGRIAIMIYYGHEGGDLERDAVLDFVIQLNQQEYTAAI
                     YRTLNQVNNPPFLVMIEKLERYRHG"
     gene            12239..12493
                     /locus_tag="VYO11_000735"
     CDS             12239..12493
                     /locus_tag="VYO11_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1595328.1"
                     /translation="MDKQYLHEKLDAMRQNFVESTHHERSVGVLDQAHMSKKMLKIKK
                     KLVALEMERCQRKIEHKDCSKIDQKIKEQKEIFESCCKKD"
     gene            12505..14559
                     /locus_tag="VYO11_000736"
     CDS             12505..14559
                     /locus_tag="VYO11_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000421632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HEV1595329.1"
                     /translation="MELLIYLILFLLVLIVSSTTNKLLPFLPLPLVQILLGIVIGLFL
                     PNTDFHLNTELFLALVIGPLLFREAEEADVTAILKHWRIIVYLIFPVIFISTLSLGGL
                     AHLLWFSLPLAACLAVGAALGPTDLVAFASLSERFSFPKRVSNILKGEGLLNDASGLV
                     AFQVALTAWTTGAFSLGQASSSLIFSILGGFLIGFLTAMTNRFLHTFLLSVRATDIAS
                     ELLLELSLPLVTFFLAEEVHVSGIIAVVVAGILKASRFKKITLLEAQVDTVTETVWHT
                     VTFMLNGSVFVILGMELEMIAEPILTNPIYNPLLLLLSLIALTFVLFVIRFIMIYGYY
                     AYRNRRLKKKLNKYMKDMFLLTFSGVKGTVSIATILLIPSNLEQEYPLLLFLVAGVTL
                     VSFLTGLLVLPHLSDEEEESKDYLMHIAILNEVTLELEKELEDTRNKLPLYAAIDNYH
                     GRIENLILSQENQDDQEDWAALKLLILSIESDGLEQAYEEGNISNRAYRVYQRYLKNI
                     EQGINRKLASRLTYYFLVSLRILRFLLHEVFTLGKTFRSWKNKEQSRLRALDYDQIAE
                     LYLANTEMIIESLENLKGVYRRSLISFMQESRLRETTIISSGAFVERVINRVKPNNIN
                     EMLRGYYLERKLIFEYEEKRLITTKYAKKLRQNVNNLENYSLKEAANTLPYDMVELVR
                     RN"
     gene            14738..15598
                     /locus_tag="VYO11_000737"
     CDS             14738..15598
                     /locus_tag="VYO11_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HEV1595330.1"
                     /translation="MKKWWKELIDKPLLKAFLHYYQASDSELTSVAVAYYWLISIFPL
                     LLVVVNILPYFQIPVGEFLGFMKDVLPPSLYEGVEKIAREVLTQPSTGLLSFSVLSAL
                     WSFSKSMNFLQKAFNKAYGVEKSRGLISHQMLSLLVSFGLQLLFAFALFLILFGQMIL
                     ALLAHYWTKDGIIYQALQGLAGPLIYALLFAILVMLYYFLPNLSNRKISYTLPGSAFV
                     LLVILGLLTLFSSYLNYYVHHLVDVRILGSVLLVVMMFWFILIAKIVILGAVINASMQ
                     SLKDPVFKKD"
     gene            15809..16519
                     /gene="ccdA2"
                     /locus_tag="VYO11_000738"
     CDS             15809..16519
                     /gene="ccdA2"
                     /locus_tag="VYO11_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000509848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HEV1595331.1"
                     /translation="MGHIFFFLSVFLAGILSFFSPCILPLLPVYTGVLLDDKDGAQAS
                     SGKFSISVTSLLRTLVFIAGISFIFILLGYGAGFLGDLLYASWFQYLTGAIIILLGLH
                     QMEILHFKGLYKEKRLQLQGQGQNGKGYSQAFLLGLTFSFAWTPCVGPVLGSVLALAA
                     SGGSGAWQGAGLMLVYTLGLALPFLLLALTSSYVLKHFRKLHPYLGILKKVGGFLIIV
                     MGFLVLFGNASILSQLFE"
     gene            16539..17105
                     /locus_tag="VYO11_000739"
     CDS             16539..17105
                     /locus_tag="VYO11_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redoxin family protein"
                     /protein_id="HEV1595332.1"
                     /translation="MKKWQTCVLGAGSLLCLTACSGKSVTSEHQTKDEMKTEQTASKT
                     SAAKGKEVADFELMGVDGKTYRLSDYKGKKVYLKFWASWCSICLASLPDTDEIAKEAG
                     DDYVVLTVVSPGHKGEQSEADFKNWYKGLDYKNLPVLVDPSGKLLETYGVRSYPTQAF
                     IDKEGKLVKTHPGFMEKDAILQTLKELA"
     gene            17116..18228
                     /gene="msrB"
                     /locus_tag="VYO11_000740"
     CDS             17116..18228
                     /gene="msrB"
                     /locus_tag="VYO11_000740"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HEV1595333.1"
                     /translation="MNDKLKIFLLLGVFFLAITGFYVLLIRNAGQTDASQIEKAAVSQ
                     GGKAVKKTEISKDADLHEIYLAGGCFWGVEEYFSRVPGVTDAVSGYANGRGETTKYEL
                     INQTGHAETVHVTYDAKQISLKEILLHYFRIINPTSKNKQGNDVGTQYRTGVYYTDDK
                     DLEVINQVFDEVAKKYDQPLAVEKENLKNFVVAEDYHQDYLKKNPNGYCHINVNQAAY
                     PVIDASKYPKPSDEELKKTLSPEEYAVTQENQTERAFSNRYWDKFESGIYVDIATGEP
                     LFSSKDKFESGCGWPSFTQPISPDVVTYKEDKSYNMTRMEVRSRVGDSHLGHVFTDGP
                     QDKGGLRYCINSLSIRFIPKDQMEEKGYAYLLDYVD"
     gene            18496..19233
                     /locus_tag="VYO11_000741"
     CDS             18496..19233
                     /locus_tag="VYO11_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1595334.1"
                     /translation="MTYTILIVEDEYLVRQGLTKLVNVAAYDMEIIGQAENGRQAWEL
                     IQKQVPDIILTDINMPHLNGIQLASLVRETYPQVHLVFLTGYDDFDYALSAVKLGVDD
                     YLLKPFSRQDIEEMLGKIKQKLDKEEKEEQLQDLLTNRFEGNMAQKIQSHLADSQFSL
                     KSLASDLGFSPTYLSSLIKKELGLPFQDYLVRERVKQAKLLLLTTDLKIYEIAEKVGF
                     EDMNYFTQRFKQIAGVTPRQFKKGEDR"
     gene            19230..20921
                     /locus_tag="VYO11_000742"
     CDS             19230..20921
                     /locus_tag="VYO11_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV1595335.1"
                     /translation="MKRSSLLVRMVISIFLVFLILLALVGTFYYQSSSSAIEATIEGN
                     SQTTISQTSHFIQSYIKKLETTSTGLTQQTDVLAYAENPSQDKVEGIRDLFLTILKSD
                     KDLKTVVLVTKSGQVISTDDSVQMKTSSDMMAEDWYQKAIHQGAMPVLTPARKSDSQW
                     VISVTQELVDAKGANLGVLRLDISYETLEAYLNQLQLGQQGFAFIINENHEFVYHPQH
                     TVYSSSSKMEAMKPYIETGQGYTPGHKSYVSQEKIAGTDWTVLGVSSLEKLDQVRSQL
                     LWTLLGASVTSLLVCLCLVWFSLKRWIAPLKDLRETMLEIASGAQNLRAKEVGAYELR
                     EVTRQFNAMLDQIDQLMVAIRSQEETTRQYQLQALSSQINPHFLYNTLDTIIWMAEFH
                     DSQRVVQVTKSLATYFRLALNQGKDLICLSDEINHVRQYLFIQKQRYGDKLEYEINEN
                     VAFDNLVLPKLVLQPLVENALYHGIKEKEGQGHIKLSVQKQDSGLVIRIEDDGVGFQD
                     AGDSSQSQLKRGGVGLQNVDQRLKLHFGANYQMKIDSRPQKGTKVEIYINRIETS"
     gene            21037..21600
                     /locus_tag="VYO11_000743"
     CDS             21037..21600
                     /locus_tag="VYO11_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HEV1595336.1"
                     /translation="MNETQIQRETRQVVEDVLEKTNLKQGVLFVLGLSSSEVLGGQIG
                     KESSQEIGELIVETILGILGSRGIHLAVQGCEHVNRALVVERQVAEQFDLEIVSVHPT
                     LHAGGSGQLAAFKFMQDPVEVEFIKAHAGLDIGDTAIGMHVKHVQVPIRPILREIGHA
                     HVTALASRPKLIGGARAHYPQDAIRKS"
     gene            21622..27324
                     /locus_tag="VYO11_000744"
     CDS             21622..27324
                     /locus_tag="VYO11_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000473008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HEV1595337.1"
                     /translation="MFKKDRFSIRKIKGVVGSVFLGSLLMAPSVVDAATYHYVNKEII
                     SQEAKDLIQTGKPDRNEVVYGLVYQKDQLPQTGTEASVLTAFGLLTVGSLLLIYKRKK
                     IASVFLVGAMGLVVLPSAGAVDPVATLALASREGVVEMDGYRYVGYLSGDILKTLGLD
                     TVLEETSAKPGEVTVVEVETPQSTTNQEQARTENQVVETEEAPKEEAPRTEESPKEEP
                     KSEVKPTDDTLPKVEEGKEDSAEPAPVEEVGGEVESKPEEKVAVKPESQPSDKPAEES
                     KVEPPVEQAKVPEQPVQPTQAEQPSTPKESSQQENPKEDRGAEETPKQEDEQPAEAPE
                     IKVEEPVESKEETKTAKGTQEEGKEGQAPVQEVNPEYKVTTGTVEKSTESELDFTTEV
                     VPDDTKYVDEEVVERQGSKGVQVTKTTYETVEVVETDKVLSTTTEVKTPVVPKVVKKG
                     TKPVEGTAVETREEVIPFATKEQEDGTLKRGTRQVAQEGVNGKKQITETYKTIRAEKT
                     NEAPTVEETVLQAPQDEIIKKGTKGLEKPTLEWVKTDKDVLKKSATASYTLNKPDGVE
                     IKSIKVALKDNTGTVIKEVTVEENNLNVTLDNLKYYQGYTLSTTMVYNRGEGEETETL
                     EDKEVQLDLKKVEIKNIKETSLMSVDDAGVETDKSLLTEKPTDVAPLYLRVTTHDNKV
                     TRLAVDKIEEVEEDGKTLYKVTAKAPDLVQRNADNTLSEEYVHYFEKQLPKIGNVYYN
                     FNELITDMQKTPNGEFKLGADLNAVNVPTPNKSYVTAKFTGKLYSEGDKHYTIHNLAR
                     PLFAQAENAHIHDINLGNVNINMPWANKTAPLGEMFKKSTIENVKVTGNVVGNNDVTG
                     MVNKLDESDMRNVAFIGNITSVGSAGWWSGGLVSESWRSNTDNSYIDTTIKGNKAKVG
                     GLIAKLNHGADPRDVGARGRLKNSVAKGTIDVRDPQETGGLLHSNWSWGLAENNITMM
                     KVKNGGEILYGSRDAEDDDYFGANWVRNNNAFVNGISEGKQSYSRSSRWKGISEDEAK
                     TRIAKMGITAHEYEITQHLTDKLNRAAFKEDTYKTTQDYKTERELAYRNIEKLQPFYN
                     KEWIINQGNKLTDGSNLMIKEVLSVIGMKNGQFVTDLSDIDKIMIHYADGTKEEKTVT
                     RKADSKVQQIREYSVEGLGDVVYTPNMVEKDRAQLITDIKAKLDSVQLISPEVRNLMD
                     KRGKAHENTDERRNGYIRNLFLEESLDEVKGNLDKLVKALVENEDHQLNGDEAAMKAL
                     VKKVEDNKAKIMLGLAYLNRYYGFKYDEKSMKDIMMFKPDFYGKNVSVLDFLIRVGSR
                     EHNIKGNRTLEAYREVIGGTIGIGELNGFLNYNMRLFTEETDINTWYKKAVSHTNYIV
                     EKQSSNPAFANKKYRLYENLNNGEHGKYILPLLTTKKAHMFLISTYNTLAFSAFEKYG
                     KNTEAEREAFKKEIDLRAQEQINYLDFWSRLAADNVRDRLLKSENMVPSAIWDNQEVP
                     GHGWADRMGHNKNGDYAPVREFYGPTGKWHGYNGTGAYAYIFTNPQNSEAVYYIISSM
                     ISDFGTSAFTHETTHINDRMAYLGGWRHREGTDVEAFAQGMLQSPAVSSPNGDYGALG
                     LNMAYKRENDGNQWYNYDSNKLDSRAKIDHYMKNYNEALMMLDHLEADAVIAKNNGDN
                     NKWFKKMDKKWRENANRNGLVGQPHQWDLLRDLNEEENKKKLTSIDDLVDGNYVTKHN
                     MPGNKHYRAEGFDTAYQTVNMMAGIYGGNTSKSAVGSISFKHNTFRMWGYFGYLDGFV
                     GYASNKYKDAANKENKGLLGDDFIIKKVSDGKFDSLEAWKKEWFKEVKAKGEKGFVAI
                     EIDGKTITNYAELRELFDKAVEADLKAGNSNQTVALKEKVYKQLLQKSDGFVGNLFKA
                     "
     gene            27399..29120
                     /gene="pabB"
                     /locus_tag="VYO11_000745"
     CDS             27399..29120
                     /gene="pabB"
                     /locus_tag="VYO11_000745"
                     /EC_number="2.6.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component I"
                     /protein_id="HEV1595338.1"
                     /translation="MHRKTVIDFRTLGERYTFTQPIKELKTRNVEEVADLLAQVESYQ
                     EQGYYVVGYVSYEAAPAFEEKLAVHKVPLLGEYLLYFTVHDRVETSPIPLTYEDIDLP
                     SNWQEVTSAADYEKAIAQIHHHLRQGDTYQVNYTVQLKQKLSANPFAIYNRMVVEQEA
                     GYNAYVEHDEMAVISMSPELFFEQNDRELTTRPMKGTTQRGVTDQEDLEQASWLEQDP
                     KNRSENMMIVDLLRNDMNRISEVGSEHVERLCQVEQYSTVWQMTSTIKSQLREDVDLV
                     EIFRSLFPCGSITGAPKIATMEIIKDLEPQPRGVYCGTIGLLLPNGRRIFNVAIRTIQ
                     LHKGQAIYGVGGGITWDSTWESEYREVHQKAAVLYRKQARFQLITTGEISQKNLLFED
                     QHLERLRKASRYFAFPFDAEDLGHKIEEECQDCEANRDYRLRISLSKSGEIEVNRQVL
                     TPLSTSFCQAQVCLQEAALNQSFTYFKTTHRPHLSLGEQEKIYHNKSGELLETSIGNL
                     VLKIAGKLYTPPIRLGILPGIYRQHLLETGQVEEKVLTLADLTQAEAIYGCNAVRGLY
                     ELSLEEN"
     gene            29121..29738
                     /locus_tag="VYO11_000746"
     CDS             29121..29738
                     /locus_tag="VYO11_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000766583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEV1595339.1"
                     /translation="MKLIFLHGLGQSAESWKEVRNLLTDYPSEAIELFPSGVSNYQQA
                     KERVYQHLAQETEPFVLIGLSLGAALTLELSSYDLPNLRALILSGCPLKLAGNILFYL
                     QLLIFKLLPKRVFEKQGADKTLMVGVSEELKTLDLTDIAGTCSYPTLLICGSKDKPNL
                     SSMKALHRLLTDSQFQIIPDGPHVLNKAKPKEFVEKTRSFLELLK"
     gene            29788..30658
                     /locus_tag="VYO11_000747"
                     /pseudo
     CDS             29788..30658
                     /locus_tag="VYO11_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042500.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
     gene            30793..31752
                     /locus_tag="VYO11_000748"
     CDS             30793..31752
                     /locus_tag="VYO11_000748"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002919069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HEV1595340.1"
                     /translation="MSQKIIGIDLGGTSIKFAILTTAGEIQGKWSIKTNILDEGSHIV
                     DDMIESIQHRLDLLGLAAADFQGIGMGSPGVVDRDKGTVIGAYNLNWKTLQPIKQKIE
                     KALGIPFFIDNDANVAALGERWMGAGDNQPDVVFMTLGTGVGGGIVAEGKLLHGVAGA
                     AGELGHITVDFDQPIACTCGKKGCLETVASATGIVNLTRRYADEYEGDAALKRLIDNG
                     EEVTAKTVFDLAKEGDDLALIVYRNFSRYLGIACANIGSILNPSTIVIGGGVSAAGEF
                     LLQGVQKVYDENTFPQVRTSTKLALATLGNDAGVIGAASLVLQ"
     gene            31849..32688
                     /locus_tag="VYO11_000749"
     CDS             31849..32688
                     /locus_tag="VYO11_000749"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003011065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HEV1595341.1"
                     /translation="MTKADTIFKENIERILKEGVFSEQARPKYKDGTVANSKYVTGAF
                     SEYDLSKGEFPITTLRPIAIKSAIKEVLWIYQDQSNSLEVLNDKYNVHYWNDWEVGDT
                     GTIGERYGAVVKKHDIINKLLKQLETNPWNRRNIISLWDYQAFEETDGLLPCAFQTMF
                     DVRRVDGEIYLDATLTQRSNDMLVAHHINAMQYVALQMMIAKHFGWKVGKFFYFINNL
                     HIYDNQFEQAQELLRREPSNCQPRLVLNVPDGTNFFDIKAEDFELVDYDPVKPQLKFD
                     LAI"
     gene            complement(32736..32906)
                     /locus_tag="VYO11_000750"
     CDS             complement(32736..32906)
                     /locus_tag="VYO11_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001051775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HEV1595342.1"
                     /translation="MAKGFAKGLVTGVAGTVAAVAGAVYAFKKKVIEPEEQKAAFIEE
                     NRKKAARRRVSR"
     gene            33027..33911
                     /gene="miaA"
                     /locus_tag="VYO11_000751"
     CDS             33027..33911
                     /gene="miaA"
                     /locus_tag="VYO11_000751"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HEV1595343.1"
                     /translation="MKTKIIVIVGPTAVGKTALAIEVAKRFNGEVVSGDSQQVYRGLD
                     IGTAKASPEEQAAVPHHLIDVREITESYSAFDFVSEAKMTIEGIHNRGKLAIIAGGTG
                     LYIQSLLEGYHLGGETPHEEILAYRASLEPYSDEELAHLVDQAGLEIPQFNRRRAMRA
                     LEIAHFGQDLENQETLYEPLIICLDDERSQLYERINHRVDLMFEAGLLDEAKWLFDHS
                     PNVQAAKGIGYKELFPYFRGEQTLEEASESLKQATRRFAKRQLTWFRNRMQVTFYQIG
                     ESGVQDRILSQIEEFLDD"
     gene            33904..35142
                     /gene="hflX"
                     /locus_tag="VYO11_000752"
     CDS             33904..35142
                     /gene="hflX"
                     /locus_tag="VYO11_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000573186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HEV1595344.1"
                     /translation="MIETEKKEERVLLIGVELQGMDSFDLSMEELASLAKTAGAVVVD
                     SYRQKREKYDSKTFVGSGKLEEIALMVDAEEITTVIVNNRLTPRQNVNLEEVLGVKVI
                     DRMQLILDIFAMRARSHEGKLQVHLAQLKYLLPRLVGQGIMLSRQAGGIGSRGPGESQ
                     LELNRRSVRNQITDIERQLKVVEKNRATVREKRLESSTFKIGLIGYTNAGKSTIMNIL
                     TSKTQYEADELFATLDATTKSIHLGGNLQVTLTDTVGFIQDLPTELVSSFKSTLEESK
                     HVDLLVHVIDASNPYHEEHEKTVLSIMKDLDMEDIPHLTLYNKADLVEDFTPTQTPYT
                     LISAKSEDSRENLQALLLDKIKEIFEAFTLRVPFSKSYKIHDLESVAILEERDYQEDS
                     EVITGYISEKNKWRLEEFYD"
     gene            35135..35758
                     /locus_tag="VYO11_000753"
     CDS             35135..35758
                     /locus_tag="VYO11_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine beta-lyase"
                     /protein_id="HEV1595345.1"
                     /translation="MTDIKALALKYGGYTSLDKVYLDQLLAGKTEQEQLTLITPPPSV
                     VNAYFAELYQKKSPQAATDYFAELSQELNLYNTEPSFTLENKPFIRLNLSGKSFGFCY
                     DSDGLGRIFSENEEKISDDLLFEIAQIFPHQLVFEESGKIYMKPVEDEEVVSLESLTA
                     LTDLERLADGRKRLKGYSQEDLLQEAAAFSGKRYFRSENRTAMLYID"
     gene            35773..36702
                     /locus_tag="VYO11_000754"
     CDS             35773..36702
                     /locus_tag="VYO11_000754"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000354350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HEV1595346.1"
                     /translation="MDIQFLGTGAGQPSKARNVSSLALKLLDEINEVWLFDCGEGTQN
                     RILETTVRPRKISKIFITHLHGDHIFGLPGFLSSRAFQANEEQTDLEIYGPQGIKSFV
                     LTSLRVSGSRLPYRIHFHEFDQDSLGKILETDKFTVYAEELDHTIFCVGYRVMQKDLE
                     GTLDAEKLKAAGVPFGPLFGKIKNGQDLVLEDGTEIKAADYISAPRPGKIITILGDTR
                     KTNASVRLAVNADVLVHESTYGKGDEKIARNHGHSTNMQAAQVAVEAGAKRLLLNHIS
                     ARFLSKDISKLKKDAATIFENVHVVKDLEEVEI"
     gene            36723..37478
                     /locus_tag="VYO11_000755"
     CDS             36723..37478
                     /locus_tag="VYO11_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEV1595347.1"
                     /translation="MPTILITGASGGLAQEMVKLLPNDQLILLGRNKEKLAQLYGNYS
                     HAELIEIDITDDSALEALVTDLYLRYGKIDVLINNAGYGIFEGFDQIADKDIHQMFEV
                     NTFALMNLSRHLAARMKESSKGHIINIVSMAGLIATGKSSLYSATKFAAIGFSNALRL
                     ELMPYGVYVTTVNPGPIRTGFFDQADPDGTYLKSVDRFLLEADAVAKKIVKIIGKNKR
                     ELNLPILLNLAHKFYTLFPKLADKLAGETFNYK"
     gene            complement(37532..38440)
                     /locus_tag="VYO11_000756"
     CDS             complement(37532..38440)
                     /locus_tag="VYO11_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEV1595348.1"
                     /translation="MRIQQLHYIIKIVETGSMNEAAKQLFITQPSLSNAVRDLENEMG
                     IEIFIRNPKGITLTRDGMEFLSYARQVVEQTQLLEERYKNPVAHRELFSVSSQHYAFV
                     VNAFVSLLKKSDMEKYELFLRETRTWEIIDDVKNFRSEVGVLFLNSYNRDVLTKMLDD
                     NHLLAHHLFTAQPHIFVSKTNPLAKKDKVKLSDLENFPYLSYDQGTHNSFYFSEEILS
                     QEHHKKSIVVSDRATLFNLLIGLDGYTIATGILNSNLNGDNIVSIPLDIDDPIELVYI
                     QHEKTSLSKMGERFIDYLLEEVQFDS"
     gene            38504..38773
                     /locus_tag="VYO11_000757"
     CDS             38504..38773
                     /locus_tag="VYO11_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HEV1595349.1"
                     /translation="MSLFLKKTQNFARMSLMKTFYDVQQFLKRFGIIVYMGKRLYDIE
                     LMKLELSRIYDAGLMDKLDYLEAEAVLRREHKVELDYIEKNGEKN"
     gene            38773..39153
                     /locus_tag="VYO11_000758"
     CDS             38773..39153
                     /locus_tag="VYO11_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEV1595350.1"
                     /translation="MVTWILWALILAMLAWMGFNYLRIRRAAKIVDNKEFEALIRTGQ
                     LIDLRDPAEFHRKHILGARNIPSSQLKTSLAALRKDKPVLLYENQRAQRVTNAALYLK
                     KQGFSEIYILSYGLDSWKGKVKTS"
     gene            39242..39469
                     /locus_tag="VYO11_000759"
     CDS             39242..39469
                     /locus_tag="VYO11_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1595351.1"
                     /translation="MKEKKKNPLFVGILSIILGLLFPIVGLILGIIGLVLAISYQKES
                     QLDYKIEKILNILGIVISVVNWIVAIALIFR"
     gene            complement(39509..40234)
                     /locus_tag="VYO11_000760"
     CDS             complement(39509..40234)
                     /locus_tag="VYO11_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001235004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEV1595352.1"
                     /translation="MRLDNLLAQEKISRKAMKQALLKGDILVDGCPARSLAQNIDTGL
                     QELLFQDRIIQGYEHTYLMLHKPAGVVTANKDKELPTVMDLLPSDIQSDKLYAVGRLD
                     RDTTGLLLLTDNGPLGFQLLHPQYHVDKTYQVEVNGLLTPDHIQTFQKGIVFLDGTIC
                     KPARLEILSASPSLSQASITISEGKFHQIKKMFLSVGVKVTSLKRIQFGDFTLNPDLA
                     EGNYRPLNQKELQIIKNYLEMSR"
     gene            40396..42237
                     /gene="typA"
                     /locus_tag="VYO11_000761"
     CDS             40396..42237
                     /gene="typA"
                     /locus_tag="VYO11_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003078415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HEV1595353.1"
                     /translation="MTKLREDIRNIAIIAHVDHGKTTLVDELLKQSETLDARTELAER
                     AMDSNDIEKERGITILAKNTAVAYNGTRINIMDTPGHADFGGEVERIMKMVDGVVLVV
                     DAYEGTMPQTRFVLKKALEQDLVPIVVVNKIDKPSARPAEVVDEVLELFIELGADDDQ
                     LDFPVVYASAINGTSSLSDDPADQEATMAPIFDTIIDHIPAPVDNSDEPLQFQVSLLD
                     YNDFVGRIGIGRVFRGTVKVGDQVTLSKLDGTTKNFRVTKLFGFFGLERREIQEAKAG
                     DLIAVSGMEDIFVGETITPTDAVEALPILHIDEPTLQMTFLVNNSPFAGKEGKWVTSR
                     KVEERLQAELQTDVSLRVDPTDSPDKWTVSGRGELHLSILIETMRREGYELQVSRPEV
                     IVKEIDGVKCEPFERVQIDTPEEYQGSVIQSLSERKGEMLDMISTGNGQTRLVFLVPA
                     RGLIGYSTEFLSMTRGYGIMNHTFDQYLPLIPGEIGGRHRGALVSIDAGKATTYSIMS
                     IEERGTIFVNPGTEVYEGMIIGENSRENDLTVNITKAKQMTNVRSATKDQTAVIKTPR
                     ILTLEESLEFLNDDEYMEVTPESIRLRKQILNKAEREKANKKKKSAE"
     gene            42257..42511
                     /locus_tag="VYO11_000762"
     CDS             42257..42511
                     /locus_tag="VYO11_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3165 family protein"
                     /protein_id="HEV1595354.1"
                     /translation="MVYLVLGILLLLLYVFATPESIKGTVNIVAMVCILVALLILLVL
                     SFLKIFQLPTEIFLAIAMLILAYFSVRDITLMPVKKSKRR"
BASE COUNT        13050 a         7996 c         9559 g        12067 t
ORIGIN      
        1 ttgctcttct ttatcatcaa taactcaagt tcaagtcaaa caaatattct ggctcagttg
       61 atggactttt tcacaggaaa tggacatctt gaagacctat caaaaatttc cgaaccagaa
      121 aaactttatg cttacattgc tgaagcaacc gcttaatctt gtctattaaa aaataaaatc
      181 ggaggaaatc taaatgatta aaattcttgc tgcctgcggt gcaggtgtta actcaagtca
      241 ccaaattaaa agtgctctag aagaagaact ttcaaaccgt ggttatgatg ttcactgtga
      301 tgcagtcatg gtgaaagatg taaacgaaga ccttatgaaa ggttacgata tctttacacc
      361 aatcgctgca acagaccttg gttttgaacc aggtatccca gttatcgaag ctggaccaat
      421 cttattccgt atcccagcaa tgagcgctcc agtatttgac aatattgaag cagctattaa
      481 agaacacgga ttaagctaat tctaatttgt taacattcat ataacataaa aaagggagga
      541 actgttatgg atgcaatctt tgacctaatc ggaaaggttt tcaatcccat cttagaaatg
      601 ggtggacctg tcatcatgtt aatcattttg acagtattgg ctttactttt tggagtgaaa
      661 ttctccaaag cgcttgaagg tggtatcaaa cttgccatcg ctcttacagg tatcggtgct
      721 atcatcggta tgctaaatgg tgctttctca gcatcacttg caaaattcgt tgaaaacact
      781 ggtatacaat tgagtattac cgacgttggt tgggcaccac ttgcaacaat cacttggggt
      841 tctgcttgga cactttactt cttgctcatc atgttgattg tcaacgtagt gatgcttgct
      901 atgaagaaaa ccgatacact tgatgtcgat atctttgata tctggcactt gtctatcaca
      961 ggtctcttga ttaaatggta tgctgataac aatggtgtga gtcaaggggt ttcactcttt
     1021 attgctacag cagctatcgt ccttgtcggt gtgttgaaaa ttatcaactc tgacttgatg
     1081 aaacctacat ttgatgacct tcttaacgcc ccaagttcat caccaatgac atcaactcac
     1141 atgaactaca tgatgaaccc agttatcatg gttttggata agatttttga aaaattcttc
     1201 ccaggccttg ataaatatga ctttgatgct gctaaattga acaagaaaat cggtttctgg
     1261 ggatctaaat tcttcatcgg tttcatcctt ggtatcgtta tcggtattat gggaactcca
     1321 catccaattg caggtgttgc agatgcagat aaatggcgtc ttgttatcaa aggatggttg
     1381 tctcttggtt tgactgccgg tgtatctttg gaactcttct cacttatcgg ttcatggttc
     1441 atcgcagccg tagaaccact atcacaaggt attacaaacg ttgctactaa acgtcttcaa
     1501 ggacgtaaat tcaatatcgg tcttgactgg ccattcatcg ctggtcgtgc tgaaatctgg
     1561 gcttgtgcca acgtacttgc accaatcatg ttgattgaag cagtgcttct ttcaaaagtt
     1621 ggaaatggta tcttgccact tgcaggtatc atcgctatgg gtgttactcc agctctcttg
     1681 gttgtaactc gtggtaaatt gctccgtatg attatcttcg gaacactctt gttgccactc
     1741 ttccttcttt caggtacact tattgcacca tttgcaacag aacttgctaa aggtgtaggt
     1801 gccttcccag aaggtgtgag ccaaactcaa ttgattactc actctactct tgaaggacca
     1861 atcgaaaaac ttcttggttg gacaattggt aacactacaa ctggtgatat caaagcaatc
     1921 cttggtgcag tagccttcct tgtattctat atcggtatct ttgcttggta cagaaaacaa
     1981 atgatcaaac gtaacgaaga gtacgcagca aaagcaaaat aatgcgctcc tataaaatat
     2041 aaactcaatg aaaatcaaag agcaaactag gaagctagcc gcaggttgct aaaaacacag
     2101 ttttgaggtt gtagatgaaa ctgacgaagt cagtaatcat atctacggca aggcgacact
     2161 gacgaagttt gaattggatt ttcgcagagt gtaaattgtt gaaactaggt tgtcatacca
     2221 tgtataccac ttgggctttg gtagtagcta actgcactaa atataatata aggagggttt
     2281 tatggggaaa ggccattgga atcggaaaag agtttatagc attcgtaagt ttgctgtggg
     2341 agcttgctca gtaatgattg ggacttgtgc agttctatta ggaggaaata tagctggaga
     2401 atctgtagtt tatgcggatg aaacacttat tactcatact gctgagaaac ctaaagagga
     2461 aaaaatgata gtagaagaaa aggctgataa agctttggaa actaaaaatg tagttgaaag
     2521 gacagaacaa agtgaaccta gttcaactga ggctattgca tctgagaaga aagaagatga
     2581 agccgtaact ccaaaagagg aaaaagtgtc tgctaaaccg gaagaaaaag ctccaaggat
     2641 agaatcacaa gcttcaagtc aagaaaaacc gctcaaagaa gatgctaaag ctgtaacaaa
     2701 tgaagaagtg aatcaaatga ttgaagacag gaaagtggat tttaatcaaa attggtactt
     2761 taaactcaat gcaaattcta aggaagccat taaacctgat gcagacgtat ctacgtggaa
     2821 aaaattagat ttaccgtatg actggagtat ctttaacgat ttcgatcatg aatctcctgc
     2881 acaaaatgaa ggtggacagc tcaacggtgg ggaagcttgg tatcgcaaga ctttcaaact
     2941 agatgaaaaa gacctcaaga aaaatgttcg ccttactttt gatggcgtct acatggattc
     3001 tcaagtttat gtcaatggtc agttagtggg gcattatcca aatggttata accagttctc
     3061 atacgatatc accaaatacc ttcacaaaga tggtcgtgag aatgtgattg ctgtccatgc
     3121 agtcaacaaa cagccaagta gccgttggta ttcaggaagt ggtatctatc gtgatgtgac
     3181 tttacaagtg acagataagg tgcatgttga gaaaaatggg acaactattt taacaccaaa
     3241 acttgaagaa caacaacatg gcaaggttga aactcatgtg accagcaaaa tcgtcaatac
     3301 ggacgacaaa gaccatgaac ttgtagccga atatcaaatc gttgaacgag gtggtcatgc
     3361 tgtaacaggc ttagttcgta cagcgagtcg taccttaaaa gcacatgaat caacaagcct
     3421 agatgcgatt ttagaagttg aaagaccaaa actctggacc gttttaaatg acaaacctgc
     3481 cttgtacgaa ttgattacgc gtgtttaccg tgacggtcaa ttggttgatg ctaagaagga
     3541 tttgtttggt taccgttact atcactggac tccaaatgaa ggtttctctt tgaatggtga
     3601 acgtattaaa ttccatggag tatccttgca ccacgaccat ggggcgcttg gagcagaaga
     3661 aaactataaa gcagaatatc gccgtctcaa acaaatgaag gagatgggag ttaactccat
     3721 ccgtacaacc cacaaccctg ctagtgagca aaccttgcaa atcgcagcag aactaggttt
     3781 actcgttcag gaagaggctt ttgatacttg gtatggtggc aagaaacctt atgactatgg
     3841 acgttttttt gaaaaagatg ccactcaccc agaagctcga aaaggtgaaa aatggtctga
     3901 ttttgaccta cgtaccatgg tcgaaagagg caaaaacaac cctgctatct tcatgtggtc
     3961 aattggtaat gaaataggtg aagctaatgg tgatgcccac tctttagcaa ctgttaaacg
     4021 tttggtcaag gttatcaagg atgttgataa gactcgctat gttaccatgg gagcagataa
     4081 attccgtttc ggtaatggta gcggagggca tgagaaaatt gctgatgaac tcgatgctgt
     4141 tggatttaac tattctgaag ataattacaa agcccttaga gctaagcatc caaaatggtt
     4201 gatttacggt tcagaaacat catcagcaac ccgtacacga ggaagttact atcgccctga
     4261 acgtgaattg aaacatagca atggacctga gcgtaattat gaacagtcag attatggaaa
     4321 tgatcgtgtg ggttggggga aaatagcaac cgcttcatgg acttttgacc gtgacaacgc
     4381 tggctatgct ggacagttta tctggacagg tacggactat attggtgaac ctacaccatg
     4441 gcacaaccaa aatcaaactc ctgttaagag ctcttacttt ggtatcgtag atacagccgg
     4501 cattccaaaa catgacttct atctctacca aagccaatgg gtttctgtta agaagaaacc
     4561 gatggtacac cttcttcctc actggaactg ggaaaacaaa gaattagcat ccaaagtagc
     4621 tgactcagaa ggtaagattc cagttcgtgc ttattcgaat gcttctagtg tagaattatt
     4681 cttgaatgga aaatctcttg gtcttaagac tttcaataaa aaacaaacca gcgatgggcg
     4741 gacttaccaa gaaggtgcaa atgctaatga actttatctt gaatggaaag ttgcctatca
     4801 accgggtacc ttggaagcaa ttgctcgtga tgaatctggc aaggaaattg ctcgagataa
     4861 gattacgact gctggtaagc cagcggcagt tcgtcttatt aaggaagacc atgcgattgc
     4921 agcagatgga aaagacttga cttacatcta ctatgaaatt gttgacagcc aggggaatgt
     4981 ggttccaact gctaataatc tggttcgctt ccaattgcat ggccaaggtc aactggtcgg
     5041 tgtagataac ggagaacaag ccagccgtga acgctataag gcgcaagcag atggttcttg
     5101 gattcgtaaa gcatttaatg gtaaaggtgt tgccattgtc aaatcaactg aacaagcagg
     5161 gaaattcacc ctgactgccc actctgatct cttgaaatcg aaccaagtca ctgtctttac
     5221 tggtaaaaaa gaaggacaag agaagactgt tttggggaca gaagtgccaa aagtacagac
     5281 cattattgga gaggcacctg aaatgcctac cactgttccg tttgtataca gtgatggtag
     5341 ccgtgcagaa cgtcctgtaa cctggtcttc agtagatgtg agcaagcctg gtattgtaac
     5401 ggtgaaaggt atggctgacg gacgagaagt agaagctcgt gtagaagtga ttgctcttaa
     5461 atcagagcta tcagttgtga aacgtattgc tccaaatact gacttgaatt ctgtagacaa
     5521 atctgtttct tatgttttga ctgatggaag tgtacaagag tacgaagtag atagctggga
     5581 gattacggaa gtagataaag ccaaactttc agtagctgga tcacgtattc aaatgactgg
     5641 tcagttagct ggagaaacta ttcatgcaac ccttgtggta gaagaaggaa atgctgcagc
     5701 acctgtagtg ccaactgtta ctgttggagg tgaagcagta acaggtctta ctagtcgaca
     5761 accaatgcaa tatcgtactc tatcttatgg tgcccaattg ccagaagtca cagcaagtgc
     5821 tgaaaatgct gatgtgacag ttcttcaagc aagcgcagca aacggcatgc gtgcaagcat
     5881 atttgttcag cctaaagatg gtggccctct tcaaacctat gcaattcaat tcctagaaga
     5941 agcaccaaaa attgctcact tgagcttgca agtggaaaaa gctgacagtc tcaaagaaga
     6001 ccaaactgtc aaattgtcgg ttcgagctca ctatcaagat ggaacgcaag ctgtattacc
     6061 agctgataaa gtaaccttct ctacaagtgg tgaaggggaa gtcgcaattc gtaaaggaat
     6121 gcttgagttg cataagccag gagcagtcac tctgaacgct gaatatgagg gtgctacagg
     6181 tcaaatcact ctcactatcc aagccaatac tgagaagaag attgcgcaat ccatccgtcc
     6241 tgtaaatgta gtgacagatt tgcatcagga accaagtctt ccagcaacag taacggttga
     6301 gtatgacaaa ggtttcccta aagctcacaa agtcacttgg caagctattc cgaaagaaaa
     6361 actagactcc tatcaaacat ttgaagtact aggtaaagtt gaaggaattg accttgaagc
     6421 gcgtgcaaaa gtctctgtag aaggtatcgt ttcagttgaa gaagtcagtg tgacaactcc
     6481 aatcgcagaa gcaccacaat taccagaaag tgttcggaca tatgattcaa atggtcacgt
     6541 ttcatcagct aaggttgcat gggatgcgat tcgtccagag caatacgcta aggaaggtgt
     6601 ctttacagtt aatggtcgct tagaaggtac tcaattaaca actaaacttc atgttcgcgt
     6661 atctgctcaa actgagcaag gtgcaaacat ttctgaccaa tggaccggtt cagaattgcc
     6721 acttgccttt gcttcagact caaatccaag cgacccagtt tcaaatgtta atgacaagct
     6781 catttcctac aataaccaac cagccaatcg ttggacaaac tggaatcgta ctaatccaga
     6841 agcttcagtc ggtgtcctat tcggagattc aggtattttg agcaaacgtt cagttgataa
     6901 cttaagcgtt ggcttccatg aagaccatgg agttggtgca ccgaagtctt atgtgattga
     6961 gtattatgtt ggtaagactg tcccaacagc tcctaaaaac cctagttttg ttggtaatga
     7021 ggaccatgtc tttaatgatt ctgccaactg gaaaccagtt actaatctaa aagcccctgc
     7081 tcaactcaag gctggagaaa tgaaccactt tagctttgat aaagttgaaa cctatgctgt
     7141 tcgtattcgc atggtgagag cagacaacaa actaggaacg tctatcacag aggtacaaat
     7201 ctttgcgaaa caagttgcgg cagccaagca aggacaaaca agaatccaag ttgacggtaa
     7261 agacttagca aacttcaacc ctgatttgac agactactac cttgagtctg tagatggaaa
     7321 agttacggca gtcacagcaa gtgttagcaa caatggcctc gctaccgtcg ttccaagcgt
     7381 tcgtgaaggt gagccggttc gtgtcatcgc gaaagctgaa aatggcgaca tcttaggaga
     7441 ataccgtctg cacttcacta aggataagaa cttactttct cataaaccag ttgctgcggt
     7501 taaacaagct cgcttgctac aagtaggtca agcacttgaa ttgccgacta aggttccagt
     7561 ttacttcaca ggtaaagacg gctacgaaac aaaagatttg tcagttgaat gggaagaagt
     7621 tccagcagaa aatctgacaa aagcaggtca atttaccgtt cgaggccatg tccttggtag
     7681 tgatcttgtt gctgaggtca ctgtacgagt gacagacaaa ctaggcgaag ctctttcaga
     7741 taaccctaac tatgatgaaa acagtaacca ggcctttgct tcagcaacca atgatattga
     7801 caaaaactct catgaccgcg ttgactatct caatgacgga gatcattcag aaaatcgtcg
     7861 ttggacaaac tggtctccaa caccatcttc taatccagaa gtatcagcgg gtgtgatctt
     7921 ccgtgaaaat ggtaagattg tagaacggac tgttgcgcaa gccaaacttc acttctttgc
     7981 agatagtggt acggatgcac catctaaact tgttttggaa cgttatgtcg gcccaggctt
     8041 tgaagtacct acctactatt caaactacca agcctacgaa tctggacatc catttaacaa
     8101 tccagaaaat tgggaagctg tgccttatcg tgcggataaa gacatcgcag ctggtgatga
     8161 aatcaacgta acatttaaag ctgtcaaagc caaagccatg agatggcgta tggagcgtaa
     8221 agctgacaag agcggtgttg cgatgattga gatgaccttc cttgcaccaa gtgaattgcc
     8281 tcaagaaagc actcaatcaa agattcttgt agatggaaaa gaacttgctg atttcgctga
     8341 aaatcgtcaa gactatcaaa ttacctataa aggtcaacgg ccaaaagtct cagttgaaga
     8401 aaacaatcaa gtagcttcaa ctgtggtaga tagcggagac gatagccttc cagtacttgt
     8461 tcgcctcgtt tcagaaagtg gaaaacaagt caaggaatac cgtatccact tgactaagga
     8521 aaaaccagtt tctgagaaga ctgttgctac tgtacaagaa gatcttccaa aactcgaatt
     8581 tgttgaaaaa gatttggcct acaagacagt tgagaaaaaa gattcaacac tgtatctagg
     8641 tgaaactcgt gtagaacaag aaggaaaagt tggaaaagaa cgtatcttta cagcgattaa
     8701 tcctgatgga agtaaggaag aaaaactccg tgaagtggta gaagctccga cagaccgcat
     8761 cgtcttggtt ggaaccaaac cagtagctca agaagctaaa aaaccacaag tgtcagaaaa
     8821 agcagataca aaaccaattg attcaagtga agctagtcaa actaataaag cccagttacc
     8881 aaatacaggt agtgcggcaa gtcaagcagc agtagcagca ggtttagctc ttctaggttt
     8941 gagtgcagga ttagtagtta ctaaaggtaa aaaagaagac tagaaatttt gataccttct
     9001 ttatcattaa agaccaaaga aaaactcttg tcctaaatag aagataaaga gtctgggaca
     9061 aaatagttct caaccacaaa aagctagaga tttccaattg cggaactcta gctttttaat
     9121 tttgagtcgt tctcttattg tatagtagat tgaaactaga atagtacact tctacttcta
     9181 aaacattgtt agaaatcgat ttgactgtcc ttatcgattt gtcctgttct tatttcattt
     9241 cactatattt taggaggtta ttggccataa gtaccaatcc catgtcaatt ctcacttgac
     9301 gcttccctct cagattacat ctcttgtaac ccaaacaagc ctttatctgc ccaaagacag
     9361 gttccacatc aatcttgcgt tgagcgaaaa tctgtctacc ttggggagat aaaagcgcct
     9421 gacattcttt agctttcaag ttttgatagc gttcgttcat atacagtccc ttttgaggga
     9481 ctgattcagg ttcatcagcg tagtaaacct tgatttcctg ttgaaagtct gtctgtgttt
     9541 tctggtactt gatatggtga aaacgatagc accagccatc aggatgtgtg tagctatcct
     9601 ccttgtcatt atagtgccaa ttcgctaagt ttttagctga ctgtttatac cctctctttt
     9661 gtttcttatc aaacatggca tatttaatca gaaggggagt gatttcttct tgaaaataga
     9721 cctgtatctg ttcttgaagt ttggcggaga atttctctgt cgttttcttc cacacaaaac
     9781 tatacttgtt ggcattggct tcaatcttag ttccgtcaat aaacaaacaa tctaaggtca
     9841 ctaactcttc catttttcaa tttttcgacc agagaaaatc ccttgtgaat aggcaaatag
     9901 aagagtagat acaagcattt tagggtgata agacgggcga tcaaaggcat gataggaggt
     9961 gtagaagtga cgttcctcca aggtattcac cactttttca atagtaaaga cgagatggtc
    10021 ttgtggtaag aaggaactga tttctagtgg taaagttgtt tgatttgtgt tatagtgaat
    10081 atgcatggga tagccttttt aaatggttta ttaagcaatt ctattttacc aagactatcg
    10141 taaccatgca aaaaaagcaa cggcaaatcc gttgcttttt ttggagataa gagactattg
    10201 tcccagcctc ttttctttgt ataaaattgt atagtgttat tgtctatact attttgtaga
    10261 gaaagcaaaa atccctagaa aatgcttagg gattcgacta tttcattaag aacaattcaa
    10321 caatcatttc tatatacatg ataagggtta ataagaatcc tgcacgccag aagaatttga
    10381 taaatttagg atagtaaaag ctgcgttttt tcaaaaggaa gaaaaagacg agaataatgg
    10441 ctaggaacga gagggctagc cccagtctag ggaggaaatt atgggtaaag gttttagctg
    10501 taatcaagta atactcaaat accaagactg gaaaagccaa atccgcaaag tttcgtccta
    10561 gtttttttaa tctaaaaagt ttggttagga taatgcagac gactaaggtc agtatcaata
    10621 ataaaataga tgctaatttc attaaaatca tacccatatt gtatcataaa aaaaggctaa
    10681 tggaaacgag aaacagagga atttatagga aagtcaggct tttgagattg tgggtgattt
    10741 ttgttataat gaaagttata aaatcttata ataccttgaa tgattattat cgaaaactct
    10801 ttggagaaaa gacttttaaa gtccctattg atgcgggatt tgactgtccc aatcgtgatg
    10861 gaactgtggc tcatggaggc tgtacttttt gtacggtttc cggttctgga gatgccattg
    10921 tggcaccaga tgcgcctatc cgtgagcaat tttataagga aattgacttt attcatcgta
    10981 agtggccaga tgtttagaag tatctggttt attttcaaaa ttttaccaac acccatgaaa
    11041 aggtggaagt tattcgagag cgttatgaac aggctatcaa tgagccaggt gtggtaggaa
    11101 tcaatattgg aacgcgccca gactgtttac cagacgaaac catcgaatat ttggctgagt
    11161 tatcggagtg catgcatgtg acggttgaat tgggcttgca aactacttat gaagcaacct
    11221 ctgacctgat taaccgtgcg cattcttatg aattgtaggt ggaaacggtc aagcgtttga
    11281 gaaagtatcc aaaaattgag attgtttccc atttgatcaa tggtttgcct ggtgaaaccc
    11341 atgagatgat ggttgaaaat gtccgccgtt gtgtcacgga taacgatatt caagggatta
    11401 aactgcattt gctccatctt atgacaaata ctcgtatgca acgagattac catgaggggc
    11461 gtttacaatt gatgagtcag gacgaatatg tcagggtcat ctgtgaccaa ctggaaatta
    11521 ttcccaaaca tatcgtcatc catcgaatta caggagatgc gcctagggat atgctgcttg
    11581 ggcctatgtg gagcctcaat aaatgggaag ctctcaacag cattgagatg gagatgcgac
    11641 gtcgtggaag tgttcaagga tgcaaggctg taaaacagga gtttgaaaat gaaaagacca
    11701 cttgagatgg cacatgattt tttggctgag gtcgtgacaa aagaggatgt cgtagtggat
    11761 gcgactatgg gaaatggtca tgacacgctt tttttagcca agctagccaa gcaagtctat
    11821 gcctttgata ttcagaagca agccttggaa aagacccaag agcgtttgca tcaggctgac
    11881 ttgacaaatg cccagttaat cttgcaaggc catgagacac tggaccagtt tgtgataaaa
    11941 gctaaggcag ggatttttaa tctgggctat ttgccgtcag ctgataagtc tgtcatcacc
    12001 cgaccgcaga caacgattga ggcattagaa aagctatgtg gcttacttgt caaaggtgga
    12061 cgaattgcta ttatgattta ctatggtcat gaaggaggcg atctcgagag agatgctgtc
    12121 ttggattttg tgatccagtt gaaccaacaa gagtacacag ctgccattta ccgaacttta
    12181 aaccaagtca acaacccgcc gtttttagtg atgattgaaa aattagagag atacagacat
    12241 ggataaacaa tacctacacg aaaagctgga tgccatgcgc cagaattttg ttgaatcaac
    12301 ccaccacgaa cgatcggtgg gcgtgctaga ccaagcgcat atgagcaaaa aaatgcttaa
    12361 aatcaagaaa aaattagttg ctcttgaaat ggaacggtgc cagagaaaaa ttgagcacaa
    12421 agactgttcc aagattgacc aaaaaatcaa agagcagaag gagatatttg aatcctgttg
    12481 taaaaaagat taaggaggac gtgcgtggaa ttactgattt acctcatcct atttttactg
    12541 gttttgattg tctcaagtac aaccaataag ctcctgccct ttttgcctct ccctttggtg
    12601 cagattcttt tgggaattgt gattggtctc tttttaccca atactgactt tcaccttaat
    12661 acggagttgt ttttggcact ggttatcgga cccttgcttt tccgagaggc tgaagaagca
    12721 gatgttacgg ctattttaaa acactggcga atcattgttt atctcatatt tccagtgatt
    12781 tttatctcga ccttgagttt gggtggcttg gcccatcttc tttggttcag ccttcccttg
    12841 gcagcttgct tggctgttgg ggcagccctt ggtcctacgg acttggtggc ctttgcctct
    12901 ctttcggagc gttttagctt tcctaagcgc gtgtccaata ttcttaaggg cgaaggactc
    12961 ttgaatgatg cttctggttt ggtggctttt caggtagctt tgacagcttg gacaactgga
    13021 gctttttctc tggggcaagc tagcagttcg ctcatctttt caatcctagg cggtttttta
    13081 attggatttt taacggccat gaccaaccgc ttcctccata ccttcttgct aagtgtgcgc
    13141 gcaacggata ttgccagtga acttttatta gaattgagtt tgcctctagt gaccttcttt
    13201 ctggcagaag aagttcatgt ttcaggtatt attgccgtcg tagttgctgg aattttaaag
    13261 gcaagtcgct tcaagaaaat cacgctcctc gaagcccaag tggatacggt gaccgagacg
    13321 gtctggcata cagtgacctt tatgctcaac ggttctgtct ttgtgatttt agggatggag
    13381 ttggaaatga tagcagaacc tatcttgacc aatccaatct ataatcctct acttttattg
    13441 ctatctctca tcgcccttac ctttgtcctc tttgtcattc gttttattat gatctatggc
    13501 tattatgcct atagaaaccg acgcctcaag aaaaagctaa ataagtatat gaaggacatg
    13561 tttctcttga ccttttcagg tgttaaggga acggtgtcga ttgctacgat tctcttgata
    13621 ccaagtaatc tagaacagga gtatcctctt ttgcttttcc ttgttgcagg tgtgacgctt
    13681 gtcagctttt taacaggtct cttggtcttg cctcatcttt ctgatgaaga ggaagaaagc
    13741 aaggattatc tcatgcatat cgccattttg aatgaagtaa cgctagagtt ggaaaaagag
    13801 ttggaagaca ccagaaataa acttcccctc tatgcggcta ttgacaatta tcatggacgt
    13861 attgaaaatc tcattttaag ccaagaaaac caggatgatc aagaagattg ggctgctttg
    13921 aaactcttga ttcttagtat tgaaagtgat ggtttggaac aggcctatga agaggggaac
    13981 attagcaatc gtgcttaccg agtttaccaa cgttatctga aaaatataga acaaggaatc
    14041 aatcgtaaac ttgcctcaag actgacctat tatttccttg tttctttgcg gattttacgt
    14101 tttctccttc atgaagtttt tactctcgga aagaccttcc gtagctggaa gaacaaggag
    14161 caaagccgtc tccgtgctct tgattatgac caaattgcag agctctatct tgccaatacg
    14221 gagatgatta ttgaaagttt ggaaaacctg aagggagtct acagacgctc tttgattagt
    14281 tttatgcagg agtctcgtct tcgagaaaca actattatca gcagtggtgc ctttgtcgaa
    14341 cgggttatca atcgtgtcaa acccaacaat atcaatgaaa tgctgagagg ctattatctg
    14401 gagcgcaagt tgattttcga atacgaagaa aaacgattaa ttacaactaa gtatgccaag
    14461 aaattacgac aaaatgtaaa taacttagag aactattcct tgaaggaagc tgccaatacc
    14521 ctgccgtatg atatggtgga attggtaaga agaaattagt taatactctt cgaaaatctc
    14581 ttcaaaccac gtcagcgtcg ccttgccgta tgtatgtgac tgacttcgtc agtcttatct
    14641 acaacctcaa aacagtgttt tgagcagctt gcggctagct ttctagtttg ctctttgatt
    14701 ttcattgagt ataagattat aaatgaagga gtatgacatg aaaaagtggt ggaaagagct
    14761 gatagacaag cctttattaa aagctttttt gcattattat caagcatcag atagtgagtt
    14821 gaccagtgtc gcagtagcct actattggtt gatttcgatt ttccccctgc ttttggtggt
    14881 ggtcaatatc ctcccctatt ttcagattcc tgtgggagaa tttctgggct ttatgaaaga
    14941 cgtcctgccc ccaagcctct atgaaggtgt ggaaaaaata gccagagaag tcttgacgca
    15001 accttcaaca ggtttattga gtttttctgt tttatcggcg ttatggagtt tttcaaaatc
    15061 tatgaatttc ttgcaaaaag cttttaacaa ggcttatggc gtcgaaaaga gtcgtggact
    15121 tatttcccat cagatgctaa gtctcctagt cagttttggc ttgcagctcc tctttgcgtt
    15181 tgccttgttt ttgattttat ttggtcagat gattttggct ttacttgctc attattggac
    15241 aaaagatggc attatctatc aggctttaca agggttggca ggtcctctga tttacgccct
    15301 cctctttgct atcttggtca tgctttatta ttttcttccc aatctatcta acaggaaaat
    15361 tagctatacc ctaccaggca gtgcctttgt tctcttagtg attttaggtt tactaactct
    15421 gttctctagt tatctcaatt actatgtcca tcatttggtg gatgtccgaa ttttaggttc
    15481 cgttcttctt gttgttatga tgttttggtt tatcttgatt gctaaaattg ttatcctagg
    15541 cgcggttatc aatgccagta tgcagagttt gaaagatccg gtctttaaaa aagactaact
    15601 atttatccat tacaaaagcg catagtatca agactttata gaaccttgat actatgcgct
    15661 tttgtgcttt gacagttttt tgtatagttt ttgtccaaga tttctaaatc atctgattaa
    15721 attcctattt tcccctatca ttgtccctgt tttttcgaaa atggaaggag tataataaat
    15781 ctatcaataa aatgatagga ggaactttat gggtcatatt ttcttttttc taagtgtctt
    15841 tttggcaggg attctatcct tcttttctcc ttgtatctta cctttgttac cggtctatac
    15901 aggagtgtta ctagatgata aggatggtgc tcaggcttct agcggcaaat tttcaatctc
    15961 agttactagt ttattacgaa ctctggtctt tatagcagga atttccttta tatttatttt
    16021 gttgggctat ggagctggtt ttttaggcga tttgctttat gcttcttggt tccaatatct
    16081 tactggggca attattatcc ttcttggttt gcaccaaatg gagattctac actttaaggg
    16141 gctttataag gaaaagaggc tacaactgca aggacagggg caaaatggta agggctatag
    16201 tcaggcattt ttattgggct tgacctttag ttttgcttgg acgccttgcg tggggccggt
    16261 tctggggtct gttttggcct tggcggcttc aggtggttca ggagcttggc agggagctgg
    16321 tctcatgttg gtgtatacgc tgggcttggc gctaccattc ttgcttctag ctctgacctc
    16381 tagttatgtt ttgaaacatt tccgaaaact tcatccctat ctcggaatcc tcaaaaaagt
    16441 gggtggtttt ctcattattg tgatgggatt cttggttctg tttggaaatg cttcaatttt
    16501 aagtcaatta tttgaataaa atggaaagga atatcaatat gaaaaaatgg caaacatgtg
    16561 ttcttggagc aggttcgctc ctttgtttga cggcttgttc aggcaagtcc gtgactagtg
    16621 aacaccaaac gaaagatgaa atgaagacgg agcagacagc tagtaaaaca agcgcagcta
    16681 aagggaaaga ggtggctgat tttgaattga tgggagtaga tggcaagacc taccgtttat
    16741 ctgattacaa gggcaagaaa gtctatctca aattctgggc ttcttggtgt tccatctgtc
    16801 tggctagtct tccagatacg gatgagattg ctaaagaagc tggtgatgac tatgtggtct
    16861 tgacagtagt gtcaccagga cataagggag agcaatctga agcggacttt aagaattggt
    16921 ataagggatt ggattataaa aatctcccag tcctagttga cccatcaggc aaacttttgg
    16981 aaacttatgg tgtccgttct tacccaaccc aagcctttat agacaaagaa ggcaagctgg
    17041 tcaaaacaca tccaggattc atggaaaaag atgcaatttt gcaaactttg aaggaattag
    17101 cctaggaggc gtcttatgaa tgataagtta aaaatcttct tgttgctagg agtatttttt
    17161 ctagccataa ccggtttcta tgttctattg atacgaaatg cagggcagac agatgcctcg
    17221 caaattgaaa aggcggcagt tagccaagga ggaaaagcag tgaaaaaaac agaaattagt
    17281 aaagacgcag acttgcacga aatttatcta gctggaggtt gtttctgggg agtggaggaa
    17341 tatttctcac gcgttcccgg ggtgacggat gccgtttcag gctatgcaaa tggtagagga
    17401 gaaacaacca agtacgaatt gattaaccaa acaggtcatg cagaaaccgt ccatgtcacc
    17461 tatgatgcca agcaaatttc tctcaaggaa atcctgcttc actatttccg cattatcaat
    17521 ccaaccagca aaaataaaca aggaaatgat gtggggaccc agtaccgtac tggtgtttat
    17581 tacacagatg acaaggattt ggaagtgatt aaccaagtct ttgatgaggt ggctaagaaa
    17641 tacgatcaac ctctagcagt tgaaaaggaa aacttgaaga attttgtggt ggctgaggat
    17701 taccatcaag actatctcaa gaaaaatcca aatggctact gccatatcaa tgttaatcag
    17761 gcggcctatc ctgtcattga tgccagcaaa tatccaaaac caagtgatga ggaattgaaa
    17821 aagaccctgt cacctgagga gtatgcagtt acccaggaaa atcaaacaga acgagctttc
    17881 tcaaaccgtt actgggataa atttgaatcc ggtatctatg tggatatagc aactggggaa
    17941 cctctctttt catcaaaaga caaatttgag tctggttgtg gctggcctag ttttacccaa
    18001 cccatcagtc cagatgttgt cacctacaag gaagataagt cctacaatat gacgcgtatg
    18061 gaagtgcgga gccgagtagg agattctcac cttgggcatg tctttacgga tggtccacag
    18121 gacaagggcg gcttacgtta ctgtatcaat agcctctcta tccgctttat tcccaaagac
    18181 caaatggaag aaaaaggcta cgcttattta ctagattatg ttgattaata ctcttcgaaa
    18241 atctcttcaa accacgtcag cgtcgcctta ccgtatgtag ggttactgac ttcgtcagtt
    18301 ttatctacaa cctcaaagct atactttgag ctgacttcgt cagttttatc tacaacctca
    18361 aagcggtact ttgagaaacc tgtggctatc ttcctagttt actttttgat ttttattgag
    18421 tataagaggt ctttcctaag cagttagagg agaattttgc tatactgata ctagtaagtg
    18481 gtaaaggagc agatcatgac ctacacaatc ttaatcgtag aagatgaata tctggtaaga
    18541 caaggtttga ctaaactggt caatgtagca gcctacgata tggaaatcat cggtcaggct
    18601 gaaaatggaa ggcaggcttg ggaattgatc caaaagcagg tgccagatat cattttaacc
    18661 gatatcaaca tgcctcatct aaatggcatc cagttggcca gtctggtacg agaaacctat
    18721 cctcaggttc atttggtctt tttaacaggt tacgatgatt ttgattatgc cttgtctgct
    18781 gtcaaactag gtgtggacga ctacctgctc aaaccctttt ctcgtcagga tattgaggaa
    18841 atgttgggga aaatcaaaca aaaactagac aaggaagaga aagaagagca gttacaagat
    18901 ttattgacta ataggtttga aggaaacatg gcccagaaaa tccagtctca tctggctgat
    18961 agccaattta gtttaaagtc tttagccagt gacttaggtt ttagtccgac ctatctgagt
    19021 tccttgatta agaaagagtt gggcttgcct tttcaggatt atctggtgag agaacgtgtt
    19081 aaacaagcca agctcttgct tttaactaca gatctgaaga tttatgagat cgcagagaag
    19141 gttggttttg aagatatgaa ctattttacc caacgtttta agcagattgc aggtgtgaca
    19201 cctcgtcagt ttaagaaggg agaagaccga tgaagcgttc ttctctttta gttagaatgg
    19261 ttatttccat ctttctggtc tttctcattc tcctagctct ggttggaact ttctactatc
    19321 aatcaagttc ttcagccatt gaggccacca ttgagggcaa cagccaaacg accatcagcc
    19381 agactagcca ctttattcag tcttatatca aaaaactaga aaccacctcg actggtttga
    19441 cccagcagac ggatgttctg gcctatgctg agaatcccag tcaagacaag gtcgagggaa
    19501 tccgagattt gtttttgacc atcttgaagt cagataagga cttgaaaact gttgtgctgg
    19561 tgaccaaatc tggtcaggtc atttctacag atgacagtgt gcagatgaaa acttcctctg
    19621 atatgatggc tgaggattgg taccaaaagg ctattcatca gggagctatg cctgttttga
    19681 ctccagctcg taaatcagat agtcagtggg tcatttctgt cactcaagaa cttgttgatg
    19741 caaagggagc caatcttggt gtgcttcgtt tggatatttc ttatgaaact ctggaagcct
    19801 atctcaatca actccagttg gggcagcagg gctttgcctt cattatcaat gaaaaccatg
    19861 aatttgtcta ccatcctcaa cacacagttt atagttcgtc tagcaaaatg gaggctatga
    19921 aaccctacat cgagacaggt cagggttata ctcctggtca caaatcctac gtcagtcaag
    19981 agaagattgc aggaactgat tggacggtac ttggcgtgtc atcattggaa aagttagacc
    20041 aggttcggag tcagctcttg tggaccttgc ttggggccag tgtcacatct cttcttgtct
    20101 gtctctgctt agtgtggttc agtcttaaac gctggattgc tcctttgaag gatttgagag
    20161 aaaccatgtt ggaaattgct tctggtgctc aaaatcttcg tgccaaggaa gttggtgcct
    20221 atgaactgag agaagtaact cgccaattta atgccatgtt ggatcagatt gatcagttga
    20281 tggtagctat tcgtagccag gaagaaacga cccgtcagta ccaacttcaa gccctttcga
    20341 gccagattaa tccacatttc ctctataaca ctttggacac catcatctgg atggctgaat
    20401 ttcatgatag tcagcgagtg gtgcaggtga ccaagtcctt ggcaacctat ttccgcttgg
    20461 cgctcaatca aggtaaggac ttgatttgtc tctctgacga aatcaatcat gtccgccagt
    20521 atctctttat ccagaaacaa cgctatggag ataaactgga atacgaaatt aatgaaaatg
    20581 ttgcctttga taatttagtc ttacccaagc tggtcctaca accccttgta gaaaatgctc
    20641 tttaccatgg cattaaggaa aaggaaggtc agggccatat taaactttct gtccagaaac
    20701 aggattcggg attggtcatc cgtattgagg atgatggcgt tggcttccaa gatgctggtg
    20761 atagtagtca aagtcaactc aaacgtgggg gagttggtct tcaaaatgtc gatcaacggc
    20821 tcaaacttca ttttggagcc aattaccaga tgaagattga ttctagaccc caaaaaggaa
    20881 cgaaagttga aatatatata aatagaatag aaactagcta actcccagtc aattctggga
    20941 gttttatgcg taattgggca agctttctag gttgtctatc ttgctaaaaa caagaaaaaa
    21001 cggtatgata gaagagtaac aacagaggta acagagatga acgagacaca gattcaaaga
    21061 gaaacacgtc aggtagtgga agatgtttta gaaaagacca atttgaagca gggggtcctt
    21121 tttgttttag gcctatcttc tagtgaggtg ctaggtggtc agattgggaa agaatccagt
    21181 caagagattg gtgagctgat agtggagact atcttgggta ttctaggtag tagaggtatc
    21241 catttagcag ttcaaggttg tgagcatgtc aatcgggctc tcgttgttga acgtcaggtg
    21301 gcagagcagt ttgatctgga aattgtcagt gtccatccta ctcttcatgc aggaggttcg
    21361 gggcagttgg cagcctttaa gtttatgcag gatccagttg aggttgaatt tatcaaggct
    21421 catgctggat tggatatcgg agacactgca attggcatgc atgtcaagca tgttcaggtt
    21481 ccgattcgcc ctattttgag agagattggt catgcccatg taacggcact ggctagtcgt
    21541 ccaaaattaa tcggaggtgc gcgtgcgcac tatccgcaag atgctattag aaagtcttga
    21601 gaatgaataa aggagatgaa agtgtttaaa aaagaccgtt tttcaattcg taagattaag
    21661 ggagttgtag gctctgtatt tcttggaagc cttttgatgg ctccttctgt agtggacgca
    21721 gctacctatc actatgtaaa taaagagatt atttcacaag aagctaaaga tttaattcag
    21781 acaggaaagc ctgacaggaa tgaagttgta tatggtttgg tgtatcaaaa agatcagttg
    21841 cctcaaacag ggacagaagc atctgttttg acagcttttg gtttgctgac tgttgggagc
    21901 ttgcttttaa tctacaagag aaagaaaatt gctagcgtct ttctagttgg agctatggga
    21961 ttggtagttc ttcctagtgc aggggctgta gacccagttg cgaccctagc gctggctagt
    22021 cgagagggtg ttgttgaaat ggatggctat cgctatgttg gttatctatc aggtgacatc
    22081 ctcaaaacgc ttggcttgga cactgtttta gaagaaacct cagcaaaacc tggagaggtg
    22141 actgtagtcg aagttgagac tcctcaatca acaacaaatc aggagcaagc taggacagaa
    22201 aaccaagtag tagagacaga ggaagctcca aaagaagaag cacctagaac agaagaaagt
    22261 ccaaaggaag aaccaaaatc ggaggtaaaa cctactgacg acacccttcc taaagtagaa
    22321 gaggggaaag aagattcagc agaaccagct ccagttgaag aagtaggtgg agaagttgag
    22381 tcaaaaccag aggaaaaagt agcagttaag ccagaaagtc aaccatcaga caaaccagct
    22441 gaggaatcaa aagttgaacc accagtagaa caagcaaaag tcccagaaca acccgtgcaa
    22501 cctacacaag ctgagcaacc aagtacacca aaagaatcat cacaacaaga aaatcctaaa
    22561 gaagataggg gagcggaaga gacaccgaaa caagaagatg aacagccagc agaagcccca
    22621 gaaatcaagg ttgaagaacc agtagaatca aaagaggaga ctaaaacagc taaggggacg
    22681 caagaagaag gcaaagaagg tcaagcacca gtacaagaag taaacccaga atataaagta
    22741 acaacaggta cagttgagaa gtctaccgaa agtgaattag atttcacaac agaagtagtt
    22801 ccggatgaca caaaatatgt agatgaagaa gttgttgaac gtcaagggtc taaaggagtt
    22861 caagttacga aaacaactta cgaaacagtg gaagttgtag agacagacaa agtcctttct
    22921 acaactacag aagtgaaaac tcctgttgtt cctaaagtcg ttaaaaaagg aacaaaacca
    22981 gttgaaggaa cagcagttga aacaagagaa gaagtcattc cttttgctac aaaagaacaa
    23041 gaagatggca ctttaaaacg cggaacaaga caagtagctc aagaaggtgt aaacggtaag
    23101 aaacaaatta ctgaaaccta taaaacaatt cgcgcagaaa aaacaaacga agctccaaca
    23161 gtagaagaaa cagttctcca agcacctcaa gatgagatta tcaaaaaagg cacaaaaggt
    23221 ttagaaaaac caaccttaga atgggttaaa acagataaag atgtcttgaa gaagagtgcg
    23281 acagccagtt atacattgaa taaaccagat ggggtagaaa tcaaatccat caaagtagct
    23341 ctaaaagata atactggaac agttattaaa gaagtaacgg tagaagaaaa taacttaaac
    23401 gttactttag acaacttgaa atattatcaa ggttatacac tatccacaac catggtctat
    23461 aatcgaggcg aaggcgaaga aactgaaacg ttagaagata aagaagttca gttagacctt
    23521 aaaaaagttg aaatcaaaaa catcaaagaa actagcttga tgagtgtgga tgatgctggt
    23581 gttgaaacag ataagagctt acttactgaa aaaccgacag acgttgctcc actttaccta
    23641 cgagtgacaa ctcatgataa caaagtaaca agacttgctg ttgataagat tgaagaagta
    23701 gaagaagacg gaaaaacttt atacaaagtt actgccaaag caccagactt agttcaacgt
    23761 aatgctgata acacacttag cgaagagtat gttcattact ttgaaaaaca acttccaaaa
    23821 attggaaatg tgtattacaa cttcaacgag ttgattacag atatgcaaaa aacaccgaat
    23881 ggcgagttta aacttggtgc agacttgaat gctgtcaatg ttccaacacc aaataaatct
    23941 tatgtgactg ctaaatttac tggtaagttg tatagtgaag gtgataaaca ctatactatt
    24001 cacaacttag cacgtccatt gtttgcgcaa gctgaaaacg ctcatattca tgacatcaac
    24061 ctcggtaatg taaatattaa tatgccgtgg gcgaacaaaa cagcacctct tggtgaaatg
    24121 ttcaagaagt caactattga aaacgtcaaa gtaacaggta atgttgtcgg taacaatgac
    24181 gttacaggta tggtcaacaa actggacgaa tctgatatgc gtaacgtagc tttcattgga
    24241 aatattacaa gtgtaggtag cgctggatgg tggtctggtg gacttgtcag tgaaagctgg
    24301 agaagtaaca cagataattc ttatattgat accaccatca aaggtaataa agctaaggta
    24361 ggtggattaa ttgctaagtt aaatcacggt gctgacccac gagatgttgg tgcgagaggt
    24421 cgtttgaaga actctgtcgc aaaaggtact attgatgtga gagacccaca agaaactggt
    24481 ggattgctgc attctaactg gtcatggggt cttgcagaaa acaatattac catgatgaaa
    24541 gtgaagaatg gaggagaaat tttatatggt tctcgtgatg cagaagatga tgattacttc
    24601 ggagcgaatt gggtgcgtaa taataatgcg ttcgtcaatg gaatcagtga agggaaacaa
    24661 tcctattctc gttctagtcg ctggaaaggg atttctgaag atgaagctaa aactcgtatt
    24721 gccaaaatgg gaattacagc tcatgaatac gaaattacac aacatttgac tgataaattg
    24781 aaccgtgcag catttaaaga agacacatat aaaacaactc aagattacaa aactgaaaga
    24841 gaattagcgt atcgtaatat tgaaaagctt caaccattct acaataaaga atggattatc
    24901 aaccaaggta acaaattaac agacggttca aacttaatga ttaaagaggt attgtccgtt
    24961 ataggtatga agaacggtca gttcgtgacc gatttgtctg atattgataa gattatgatt
    25021 cactacgctg atggtacgaa agaagaaaaa actgtcacac gtaaagctga ctcaaaagtg
    25081 caacaaattc gtgaatatag tgttgaaggt cttggtgatg ttgtgtacac accaaatatg
    25141 gtcgaaaaag atagagcgca attaattact gatattaagg cgaaattgga tagcgtccaa
    25201 ttgatttcac cagaagtgcg caatttgatg gataaacgtg gcaaagcgca tgaaaacacg
    25261 gatgaacgtc gtaatggcta cattcgaaac ctattccttg aagaaagttt ggatgaagtg
    25321 aaaggaaacc ttgataagct tgtgaaagct cttgttgaaa atgaagacca tcaattgaat
    25381 ggtgatgaag cggcaatgaa agctcttgtc aagaaagttg aagacaacaa agcgaaaatc
    25441 atgttaggtc ttgcttatct caatcgctac tatggattca aatatgacga aaagtctatg
    25501 aaggatatta tgatgttcaa accggacttc tatggtaaga atgttagtgt cttggacttc
    25561 ttgattagag ttggttcaag agaacacaat attaaaggta acagaacgtt agaagcttat
    25621 cgtgaagtaa ttggtggaac gattggtatc ggtgagttaa acggtttctt aaactataat
    25681 atgcgtttat tcacagaaga aactgacatc aatacttggt acaaaaaagc tgtatcgcat
    25741 accaactata ttgttgaaaa acaatcctca aaccctgcgt ttgccaacaa gaaatatcgc
    25801 ctttatgaaa acttgaacaa tggtgaacat ggtaaatata ttttaccact tctcactacg
    25861 aagaaagctc atatgttctt gatttcaacc tataatacat tagcgtttag tgcgtttgag
    25921 aaatatggta agaatacaga agctgaacgt gaagcgttta agaaagaaat cgatttacgt
    25981 gctcaagagc aaattaatta cttagacttc tggtcaagac ttgcagctga taatgtacgt
    26041 gacagattgt taaaatctga aaatatggtt ccgtctgcaa tttgggataa ccaagaagtt
    26101 ccaggtcatg gatgggctga tagaatgggt cataataaga atggtgacta tgctccggtt
    26161 cgtgagttct atggacctac aggtaaatgg catggataca atggtacggg tgcatatgct
    26221 tatatcttta ctaatccaca aaactcagaa gctgtatatt atatcatatc tagtatgatc
    26281 agtgatttcg gtacttctgc attcactcat gaaactacac acattaatga ccgtatggcg
    26341 tatctaggtg gatggcgtca ccgtgaaggt actgacgtag aagcatttgc ccaaggtatg
    26401 ttacaatcac cggctgtctc aagtccgaac ggcgactacg gtgctttagg tcttaacatg
    26461 gcttacaaac gtgaaaacga tggtaaccaa tggtacaact atgattcaaa taaattagat
    26521 agtcgtgcga agattgacca ttacatgaag aattacaacg aagcgctcat gatgcttgac
    26581 cacttagaag ctgatgccgt tatcgcgaag aataacggag ataacaacaa gtggttcaag
    26641 aagatggata agaaatggcg tgagaacgct aatcgaaatg gattagtggg acaaccacac
    26701 caatgggatt tacttcgtga cctaaatgaa gaagagaata agaagaaatt gacaagcatt
    26761 gatgaccttg tagatggaaa ttatgtaacg aagcataata tgccgggtaa taaacactat
    26821 cgtgctgaag ggtttgatac agcgtatcaa actgtaaaca tgatggctgg tatttacggt
    26881 ggtaatacta gtaagagtgc tgttggttct atctcgttca aacataacac cttccgtatg
    26941 tggggttact tcggttatct tgatggattt gtaggttatg catctaacaa atataaagac
    27001 gcggctaaca aagaaaataa aggcttactt ggcgacgact ttattatcaa gaaagtgtct
    27061 gacggtaaat ttgacagcct agaagcttgg aagaaagaat ggtttaaaga agttaaagct
    27121 aaaggtgaaa aaggatttgt tgctattgaa attgatggta aaacaatcac taactatgct
    27181 gaacttcgtg aattgttcga caaagctgtt gaagctgacc tgaaagctgg taactctaac
    27241 caaacagttg cccttaaaga aaaggtttat aaacaactct tgcagaaatc agatggattt
    27301 gtaggaaatc tttttaaagc atagattgta ttaaatagat gagtaaaaaa ggtagattaa
    27361 gtttttcttg atctgccttt ttatgctata cttaaggtat gcatagaaaa acagtgattg
    27421 attttaggac tttgggggag agatatacct ttacccagcc tattaaagag ttgaaaacga
    27481 gaaatgtaga agaagtggca gatttgctgg cacaagtgga aagctaccaa gagcaaggtt
    27541 attatgtggt ggggtatgtc agctacgagg ctgcacctgc ttttgaggag aaattagcag
    27601 ttcacaaggt tcctctactg ggcgagtact tgctttactt tactgttcac gatagggtag
    27661 agacctcccc tattcctctg acttatgagg atattgattt gccctcaaat tggcaggaag
    27721 tgacgtctgc agcagactat gaaaaggcca ttgcccagat acaccatcac ttgaggcagg
    27781 gagacaccta tcaggtcaac tacaccgtcc aactcaagca aaagttaagt gccaatcctt
    27841 ttgccatcta caatcgtatg gtggtagagc aggaggcggg ctacaatgcc tatgtggaac
    27901 atgacgagat ggcagtgatt tccatgagcc cagagctctt ttttgagcaa aatgatcgcg
    27961 agttgacaac acgaccaatg aaggggacga ctcagcgtgg ggtaactgac caagaagatc
    28021 ttgaacaggc cagttggttg gaacaggatc ccaaaaatcg ctctgaaaat atgatgattg
    28081 tggacctctt gcgcaatgat atgaaccgta tttctgaagt tgggagcgag cacgtggagc
    28141 gtctgtgtca ggtagagcag tattcaactg tttggcagat gacttcgacc atcaagagtc
    28201 agttgcgaga ggatgtggac cttgttgaaa tcttccgctc actctttcct tgtggttcca
    28261 taacgggtgc accgaaaatt gcgacaatgg agattatcaa ggacttggag cctcaaccgc
    28321 gtggagtcta ctgtggaacg attggtctct tgcttccaaa tggacgacgg atttttaatg
    28381 tggccattcg taccattcaa cttcacaaag gtcaagccat ttatggagtt ggcggaggga
    28441 ttacttggga tagcacatgg gaatctgaat accgagaggt tcatcaaaag gcagcagttc
    28501 tttatcgtaa acaagctcgc ttccaactga ttacgacagg ggaaatcagc cagaagaacc
    28561 tgctgtttga agatcaacat ctggaaagac tgagaaaagc tagtcgttat tttgcttttc
    28621 cttttgatgc agaagacttg ggacacaaga ttgaggaaga gtgtcaggat tgtgaagcta
    28681 atcgagatta ccgcttgcga atcagcctta gcaaatctgg agagatagaa gtcaatcgtc
    28741 aagtattaac ccctctcagt acaagctttt gtcaggccca agtctgtctt caggaagctg
    28801 ctttgaatca atcctttacc tactttaaaa ccactcaccg accgcatttg agcctaggag
    28861 aacaagagaa gatttaccac aataagtcag gagaactgct tgaaacctct ataggaaatt
    28921 tggttctgaa aatcgctgga aaactctaca caccgcctat ccgacttgga atcttgccag
    28981 gaatttaccg tcagcatttg ctagaaacag gacaggtaga agagaaagtc ttgaccttgg
    29041 cagatttaac ccaagcagaa gctatttacg gctgtaatgc agtgagaggc ttgtatgaac
    29101 taagccttga ggagaactag atgaaattga tatttttgca tgggttaggg cagtcagcag
    29161 agtcttggaa agaagttcgg aatctactga cagattatcc ttctgaggct atcgagttat
    29221 ttccttctgg agttagtaac tatcaacaag ctaaagagcg agtttatcag cacctagctc
    29281 aagagacaga accttttgtt ttgattggat tgtccttagg tgctgccctg acactagaac
    29341 tttccagtta cgatttacca aatcttcgag ctttgattct gtcaggatgc ccgcttaaat
    29401 tagcagggaa tatcctattt tatcttcaat tgctgatttt taaactactt cccaaaagag
    29461 tatttgaaaa acagggagca gacaagactc ttatggtcgg agtttctgag gaattgaaga
    29521 cacttgattt aacggatata gcagggactt gctcctatcc aaccttacta atttgtggca
    29581 gcaaagataa accgaatctt agttctatga aagctctcca tagactgtta acagattcgc
    29641 agtttcagat cattcctgat ggccctcatg tcttgaataa ggcaaaacca aaggagtttg
    29701 tagaaaagac cagaagtttc cttgaattgc tgaaataagt ttgataaaat aatattgaaa
    29761 tcgatatcat aattatggga gaaagaaatg aataaacgtc tatttttaaa aatgagtctg
    29821 gtgacgttgc caattttagc cttgttttca caaccagttt tggcggaaga aaacatccat
    29881 ttttcgagct gtaaggaagc ttgggcgaat ggctattcgg atattcacga gggggaacct
    29941 ggttattctg ccaagttaga ccgtgatcat gatggtgtgg cttgcgaatt gaaaaatgct
    30001 cctaagggtg cttttaaagc aaaacagtca acggctattc aaatcaacac aagttcagca
    30061 acaacaagtg gttgggttaa gcaggacggc gcttggtact actttgatgg aaatggaaat
    30121 ctagtgaaaa atgcatggca gggaagctat tacctgaaag ctgatggtaa aatggcacaa
    30181 ggtgagtggg tttatgattc ttcttaccaa gcatggtatt acttgaaatc agatggttca
    30241 tatgctcgca atgcatggca aggaaactac tatttgaaat cagatggtaa aatggctaaa
    30301 ggtgaatggg tttatgatgc cacctatcaa gcttggtatt atttgacatc agatggttct
    30361 tatgcttaca gtacatggca aggaaattac tatctaaaat cggatggtaa aatggctgtc
    30421 aatgaatggg ttgatggtgg acgttattat gttggcgctg acggagtttg gaaggaaggt
    30481 caagcaagta cagcttcttc tagtaatgat agcaatagtg aatattctgc tgctttagga
    30541 aaggcaaaaa gttataattc gttattccac atgtcaaaaa aaacgtatgt atagacaatt
    30601 aacttctgat tttgataaat tttcaaatga tgcagctcaa tatgccattg atcattagat
    30661 gattaacaga tactggtagg cgaaaaaatt ccttataatt cacttacgca aacctttgca
    30721 taagtgaatg gattttgata tactagtact gtaagcattt tcaattacta cacaatgaaa
    30781 aaggagaata tgatgagtca aaagattatt gggattgacc ttggtggaac ttctatcaaa
    30841 tttgcaatct taacaacagc aggagaaatc caaggaaaat ggtcaatcaa gaccaacatt
    30901 ttggatgagg gaagtcatat cgttgatgat atgattgagt ctattcaaca tcgtttggac
    30961 ttgcttggat tggcagcagc ggacttccaa ggcattggaa tgggatcacc aggtgtggtt
    31021 gaccgtgaca aagggactgt tatcggtgcc tacaacttga actggaaaac ccttcaacca
    31081 atcaaacaaa agattgaaaa agccttgggc attccatttt tcatcgataa tgatgccaac
    31141 gtagcagctc ttggtgagcg ctggatgggt gctggagata accaaccaga cgttgtcttt
    31201 atgacactcg gtactggtgt tggtggtggt attgtcgcag aaggcaaatt gcttcatggt
    31261 gttgctggtg cagcaggtga acttggtcat atcactgttg attttgacca accaattgca
    31321 tgtacttgtg gtaaaaaagg ctgccttgag acagttgctt cagcaacagg aattgtcaac
    31381 ttgactcgtc gctatgccga tgaatacgaa ggcgatgcag ccttgaaacg cttgattgat
    31441 aacggagaag aagtaactgc taagactgtc tttgatctcg caaaagaagg agacgacctt
    31501 gctttgattg tttaccgtaa cttctcacgt tacttgggaa tcgcttgtgc taacattggt
    31561 tcaatcctaa acccatcaac aatcgtcatc ggtggtggtg tgtcagctgc gggagaattc
    31621 cttctacaag gtgttcaaaa agtctatgat gaaaatactt tcccacaagt acgcacatct
    31681 actaaattag ctcttgcaac tctaggaaat gacgctggag ttatcggagc agcatcactt
    31741 gtattgcaat aagataatga gagaggaaaa tgctaaccta gagttagtaa tgttcctctt
    31801 ttatttttta tgctatacta gttaggacaa tgaatgaggt gagagtaaat gacaaaagca
    31861 gatacgattt ttaaagagaa tattgaacgc attctaaagg aaggtgtttt ctcagagcag
    31921 gctcgtccta agtacaagga tgggactgtt gctaattcca agtatgtaac tggtgccttt
    31981 tccgagtacg acttatctaa aggagaattt cctatcacaa ccttgcgtcc cattgcaatc
    32041 aaatccgcca tcaaagaagt tctctggatt taccaagacc agtcaaatag cttagaagtg
    32101 cttaatgaca agtacaatgt tcactactgg aatgactggg aagttggaga cacgggaacc
    32161 attggtgagc gctatggtgc cgttgttaag aaacacgaca ttatcaataa gcttctcaaa
    32221 cagttggaaa ccaatccttg gaaccgccgc aatattattt ctctctggga ttaccaagct
    32281 ttcgaagaaa cagatgggct gctcccgtgc gcctttcaga ccatgtttga tgttcggcgt
    32341 gttgatgggg aaatctatct ggatgcgacc ttgacccagc gctccaatga tatgctggtg
    32401 gcccaccaca tcaacgctat gcagtatgtg gctttgcaga tgatgattgc caaacatttt
    32461 ggctggaagg ttgggaagtt cttctacttc atcaacaacc tccatatcta tgataatcaa
    32521 tttgaacaag ctcaggaatt gctccgtcgg gagccgtcaa actgccaacc acgcttggtt
    32581 ttaaatgttc ctgatgggac taatttcttt gatatcaaag cagaagattt tgagttggtg
    32641 gattatgacc ctgttaagcc acagttgaag tttgacctag ctatttaaaa gaatagaaaa
    32701 aagaagttga gaataatccc aacttctttt gtttcttaac gcgatactcg gcgacgagct
    32761 gcttttttac ggttttcttc gatgaaagct gctttttgct cttctggttc gattactttc
    32821 tttttaaatg cgtatactgc acctgcaacg gcagcgacag ttcctgcgac acctgttaca
    32881 agacctttag cgaatccttt agccatgagt cttcctcctt tatattctca atcagccagc
    32941 ctcctcaaga ggtcacattt ttctgactga cctttttgtg ttataataat agtaacgaaa
    33001 aaatgggaat ttttcaagga aaaaagatga aaacaaaaat aattgtgatt gttggaccga
    33061 ctgctgttgg aaagacggct ctagctattg aagttgcaaa gcgttttaat ggcgaagtgg
    33121 ttagtggaga tagccagcaa gtctatcgag gacttgatat tgggacggcc aaggctagtc
    33181 cagaagagca ggcagctgtt cctcatcatt taatcgatgt tagagagata accgagtctt
    33241 actcggcttt tgattttgtt tcagaagcta agatgactat tgagggtatt cacaaccgtg
    33301 gcaagctagc cattatcgcc ggtgggactg gactttatat ccagagcttg ctagaaggtt
    33361 accacctagg tggggagact cctcatgagg agattttagc ttatcgagct agtttggagc
    33421 catattcaga tgaggaatta gcccatttgg tggatcaagc aggccttgag attccccagt
    33481 ttaatcgtcg tcgtgctatg cgtgccttag aaattgccca ttttggtcag gatttggaaa
    33541 atcaagagac cttgtatgaa ccgctgatta tctgcttgga tgatgaacgt agtcaacttt
    33601 atgagcgtat caaccaccga gtggatttga tgtttgaggc tgggcttttg gatgaggcca
    33661 agtggctgtt tgaccattcc cctaatgtac aggctgctaa aggaattggc tataaggaac
    33721 tctttcctta tttccgtgga gagcagacct tggaggaagc tagtgagagt ctcaaacagg
    33781 cgacccgtcg ttttgccaag cgtcagctga cctggttccg taatcgcatg caggtcacct
    33841 tttatcagat tggagaatct ggtgtacaag accgcatttt aagccagata gaggagtttt
    33901 tagatgattg aaacggagaa aaaagaggag cgagtcctgc tgattggtgt ggaattgcag
    33961 ggtatggaca gttttgacct ctccatggaa gaattggcta gtttagcgaa aacggcaggg
    34021 gcagtcgttg tagatagcta cagacaaaaa cgtgaaaaat atgattccaa gaccttcgtc
    34081 ggctctggta agttggaaga gattgcgctt atggtggatg cagaagaaat cactactgtc
    34141 atcgtcaaca accgtctgac cccaaggcag aatgtcaatc tagaggaagt tctcggtgtt
    34201 aaggtcattg accgtatgca gttgattttg gatatctttg ccatgcgggc tcgaagccat
    34261 gaagggaagc tccaagtcca cttagcccaa ctcaaatacc tcttgcctcg cttggttggt
    34321 caggggatta tgctcagccg tcaggcaggg ggaattggtt cccgtggtcc tggtgaaagc
    34381 cagctggagc tgaaccgtcg tagcgttcgc aatcaaatca cggatattga gcgccagctc
    34441 aaggtggttg agaaaaatcg ggcgactgtc agagaaaaac gtttggagtc tagcactttt
    34501 aagattggtt tgattggtta tactaatgct gggaaatcaa ctatcatgaa catcttgacc
    34561 agtaagaccc agtatgaagc agatgagctc tttgcgactc tggatgcgac aaccaagagt
    34621 attcatctgg gaggcaatct ccaagtaact ttgacagata ccgttggctt tatccaagat
    34681 ttgccgacag agttggtgtc cagtttcaag tcaaccttgg aagaaagcaa gcatgtggac
    34741 cttctggttc atgttatcga tgctagcaat ccttaccacg aggagcatga aaaaacggtt
    34801 ctctccatca tgaaagacct ggacatggaa gatattcctc acttgacgct ttataataaa
    34861 gcggatttgg tggaggattt cacgcctacc caaacgccat ataccctcat ttctgccaag
    34921 tctgaggaca gtcgtgaaaa cttgcaagca ttattgctag ataagattaa ggaaattttt
    34981 gaagcattta ccctgcgagt gcctttttca aagtcctaca agattcatga tttagagagt
    35041 gttgcaattc tggaagaacg tgattatcag gaagacagcg aagtgattac aggctacatt
    35101 tccgaaaaaa ataaatggag gttagaagaa ttttatgact gatattaaag ctttggctct
    35161 aaagtatgga ggttatacaa gtctggacaa ggtctatctg gatcagcttc tagctggtaa
    35221 aacagagcag gagcagttaa cacttattac acctccgcca agtgttgtta atgcctactt
    35281 tgcagaactc tatcagaaaa aaagtcctca ggctgcgacg gattattttg cagaactcag
    35341 tcaggaactg aatctttaca atactgagcc aagtttcacc ctagaaaata agccttttat
    35401 tcggcttaat ctgtctggta aatcctttgg tttttgttat gatagtgacg gccttggtcg
    35461 gattttctct gaaaatgagg agaaaatctc ggatgacttg ctctttgaaa ttgcgcaaat
    35521 tttcccccat caattagtct ttgaagagtc tggtaagatt tacatgaagc ctgtcgagga
    35581 cgaggaagtt gtcagcctag aaagtctcac agctttgact gatttggaaa gattggctga
    35641 tggtcgaaaa cgtctcaaag gctacagcca agaggattta ttgcaagaag ctgctgcttt
    35701 ttctggcaaa cgctatttcc gatcggaaaa ccgcacagcc atgttatata ttgattaatt
    35761 agaaagtatc gaatggatat tcaattttta ggaacggggg ctggtcagcc ctctaaagct
    35821 cgcaacgttt caagtctcgc cctgaaactt ttggatgaga ttaacgaagt ttggctcttt
    35881 gactgtggag aaggtacgca aaatcgcatt ctggaaacca cagttcgacc acgtaagatc
    35941 agcaaaatct ttattaccca tctgcatgga gaccacattt ttggtttgcc aggtttcctt
    36001 tctagccgtg cctttcaggc caatgaagag cagacagatt tggaaatcta cggacctcaa
    36061 ggaatcaagt catttgtctt aaccagcctt cgtgtgtcag gttctcgtct gccctaccgc
    36121 attcatttcc atgagtttga ccaagattct ctaggaaaaa tccttgagac cgataaattc
    36181 actgtgtatg cagaggagct ggaccatact attttctgtg ttggctatcg tgtcatgcaa
    36241 aaggatctag aagggacgct ggatgctgaa aaactcaagg ctgctggtgt tccgttcggc
    36301 ccgctttttg gtaaaatcaa aaacggccag gatcttgttt tggaagacgg aactgaaatc
    36361 aaggcggctg actatatctc agcgccacgt ccaggtaaga ttatcactat tttaggagac
    36421 actagaaaaa ccaatgctag tgtgcgtctg gctgtcaatg cagatgtcct agttcatgag
    36481 tccacttatg gcaagggtga tgaaaaaatt gctcgtaacc atggtcactc aactaatatg
    36541 caagctgcac aagtagcggt agaagcaggt gccaaacgcc tcctactcaa ccatatcagt
    36601 gcccgtttcc tctcaaaaga tattagcaaa ctcaagaaag acgctgccac aatttttgaa
    36661 aatgtccatg tggtcaaaga cttggaagaa gtggaaatct agcagtcaca gaaaggataa
    36721 gtatgcctac tattctcatt accggagcta gcggtggtct agctcaagaa atggtcaaac
    36781 tcctgcccaa tgaccaactc atcttgcttg gtagaaataa ggaaaaatta gcccaactct
    36841 acggaaatta ttcccatgca gaattgattg aaattgatat taccgacgat tcagccctag
    36901 aagctctggt aactgatctt tatctccgct atggcaagat tgatgtcttg attaacaacg
    36961 ctggttacgg gatttttgag ggatttgacc agattgctga taaagacatt caccagatgt
    37021 ttgaggtcaa tacctttgcc ctgatgaatc tgtctcgtca ccttgcggct cgtatgaagg
    37081 aaagcagcaa agggcatatc atcaacatcg tcagcatggc aggtctaata gctactggca
    37141 agtctagtct ttactcagcg accaagtttg cggctattgg tttttcaaat gctctgcgac
    37201 tcgaacttat gccctatgga gtctatgtga caacagtcaa tccaggtcca atccgaacag
    37261 gattttttga ccaagctgac ccagatggaa cttatcttaa atcggttgac cgcttcctct
    37321 tagaggcaga tgcagtggct aaaaagattg tcaagattat aggaaaaaat aaacgagaac
    37381 tcaatctccc gattttgttg aacctagccc ataagtttta tactctcttt cccaagctag
    37441 ctgataagtt ggcaggggaa acttttaatt ataagtaaaa agaaccaatg tgcaggttgt
    37501 tgctagccta catattggtt cttatcattt ctcaactatc aaactgaact tcttctagta
    37561 gatagtcgat aaagcgttcg cccatcttag ataggctggt tttctcatgc tggatataga
    37621 ccagctcaat cgggtcatca atatccagtg ggatagaaac gatattgtct ccgtttaggt
    37681 tgctgttcaa aatccctgtc gcaatggtat aaccatccaa accaatcaag agattaaaga
    37741 gggtggcacg gtcactgacc acaatggatt tcttgtggtg ttcttgagaa agaatctctt
    37801 ctgaaaagta gaaggagttg tgcgtccctt ggtcatagct gaggtaaggg aaattctcca
    37861 aatcagacag tttcaccttg tctttctttg ccagagggtt ggtcttgctg acaaagatat
    37921 gcggttgcgc tgtgaagaga tggtgggcta gcaggtgatt gtcatccagc atcttggtta
    37981 aaacatcacg gttgtaactg tttaagaaga ggaccccgac ctcactgcgg aagttcttga
    38041 cgtcgtcgat aatctcccaa gtccgagttt cacgaaggaa gagttcgtat ttctccatat
    38101 cgcttttctt gagcaaagag acaaaggcat tgaccacaaa ggcatagtgt tgagacgaaa
    38161 cgctaaagag ttcgcggtgg gcgacaggat ttttatagcg ttcctccaga agctgggtct
    38221 gctcgacaac ctgacgggca taagagagaa actccatccc atcacgggtc aaggtgattc
    38281 ccttgggatt gcggataaag atctcaatgc ccatttcatt ttccaaatct cgcactgcat
    38341 tggagagact tggctgagtg ataaagagtt gcttggctgc ctcattcatg gagccagttt
    38401 cgacgatttt gataatataa tgtaattgtt gaattctcat gtttttattg taccatactt
    38461 gccttagaat cgctaaagaa gataggaaaa taaggagcat tgtatgagtc tcttcttgaa
    38521 aaaaacacaa aattttgcta gaatgagtct tatgaaaaca ttctatgatg tgcagcaatt
    38581 cctcaaacga tttggtatta ttgtttacat gggaaaacgc ttatatgata ttgaactgat
    38641 gaagttggaa ctatctcgga tttacgatgc agggttgatg gataaattag actatctaga
    38701 ggcagaagca gttcttcgca gagagcacaa ggtagaattg gattatattg agaaaaatgg
    38761 agaaaagaac taatggttac ttggattttg tgggcactta tactagcaat gttggcgtgg
    38821 atgggcttta actatcttcg tattcgccgt gcggctaaaa ttgtggacaa taaggagttt
    38881 gaagccttga ttcgtacggg tcaattgatt gatttgcgcg acccagcaga attccacaga
    38941 aaacatatcc ttggtgcacg caatattcct tcaagtcagt tgaaaactag tcttgcagca
    39001 cttcgtaaag ataaacctgt ccttctctac gaaaaccaac gtgcgcaacg agttacaaat
    39061 gcagctcttt acttgaaaaa acaaggtttt tctgagattt atatcctttc ttatggcttg
    39121 gattcttgga aagggaaagt gaagactagc taaccttatt tccaaattag tcgaatgata
    39181 ggatgaagct attgttttat agtataatta atttgtataa aatttaaaga gttcttagaa
    39241 catgaaagaa aagaagaaaa atccactttt tgtgggtatc ttgtcgatta ttcttggttt
    39301 gttatttcca attgtaggcc tgattttggg tatcatagga ttggtcttgg ctatttcata
    39361 ccaaaaagag tcacaattag actataaaat agaaaagatt cttaatatct taggaattgt
    39421 gatttctgta gttaactgga ttgtagcaat cgccttaatt tttcggtaaa taaaagaaaa
    39481 aagctttagt tttaaagctt tttttatttt atcgactcat ctctaaatag tttttaatga
    39541 tttgtaactc tttttggttc aaagggcggt agttaccttc tgctaaatct gggttcaatg
    39601 tgaagtcccc aaattggatt ctcttgaggc tagtcacctt aacaccaacc gagaggaaca
    39661 ttttcttgat ttgatgaaat tttccttctg aaatggtgat agaggcttga ctgagggaag
    39721 gacttgctga tagaatctct agtcttgcag gtttacagat agtgccatct aaaaagacaa
    39781 ttcctttttg aaaggtttgg atatggtcag gtgttagaag tccattaacc tcaacttgat
    39841 aagtcttatc gacatgatat tggggatgga ggagttggaa gcccaaggga ccgttatcgg
    39901 tcaagagaag gagtcctgtt gtatctcggt ccagtcggcc gacggcatag agcttgtcag
    39961 actggatgtc agatggaagc aagtccatga cggtcggaag ttccttgtct ttgttggctg
    40021 taacgacacc agcaggttta tgaagcataa gataggtgtg ttcatagcct tgaatgattc
    40081 gatcctgaaa aaggagttct tgtagtcctg tatcgatatt ttgagctagg gagcgggctg
    40141 ggcaaccatc gactagaatg tcccctttga gtaaggcttg tttcatggcc tttcggctga
    40201 ttttttcttg agctaataaa ttatctaaac gcatactgtg cctatcttat cataagtcgc
    40261 ttgctttgaa aaggcttgac gtgaaaagaa aagtggagtg aaaacattta cacttgcttg
    40321 agttatgtta tttacttgaa attatggtat aatcgttcag ttagaaaata aattttgaat
    40381 attatagagg aaatcatgac aaaattaaga gaagatatcc gtaacattgc gattatcgcc
    40441 cacgttgacc acggtaaaac aaccctggtt gacgaattat tgaaacaatc agaaacgctt
    40501 gatgcacgta ctgaattggc agagcgtgct atggactcaa acgatatcga aaaagagcgt
    40561 ggaattacca tccttgctaa aaatactgcc gttgcttaca acggaactcg tatcaacatt
    40621 atggacacac caggacacgc ggacttcggt ggagaagttg agcgtatcat gaaaatggtt
    40681 gacggtgttg tcttggtcgt agatgcctat gaaggaacca tgccacaaac tcgtttcgta
    40741 ttgaaaaaag ccttggaaca agaccttgtc ccaatcgtgg ttgttaacaa aatcgataag
    40801 ccatcagctc gtccagcaga agtagtggat gaagtcttgg aacttttcat cgagcttggt
    40861 gcagatgacg accagcttga tttcccagtg gtttatgctt cagcgatcaa cggaacttct
    40921 tcattgtcag atgatccagc tgaccaagaa gcgactatgg caccaatctt tgacacgatt
    40981 atcgaccata tcccagctcc agtagataac tcagatgagc ctttgcagtt ccaagtgtcg
    41041 cttttggact acaatgactt cgttggacgt atcggtatcg gtcgtgtctt ccgtggtaca
    41101 gttaaggttg gggaccaagt taccctttct aaacttgacg gtacaactaa aaacttccgt
    41161 gttacaaaac tcttcggttt ctttggtttg gaacgtcgtg aaatccaaga agccaaagcg
    41221 ggtgacttga ttgccgtttc aggtatggaa gacatctttg tcggtgaaac catcactccg
    41281 acagatgcag tagaagctct tccaatccta cacatcgatg agccaactct tcaaatgact
    41341 ttcttggtca acaactcacc atttgctggt aaagaaggta aatgggtaac ttctcgtaag
    41401 gtggaagaac gcttgcaggc agaattgcaa acagacgttt cccttcgtgt tgacccaact
    41461 gattcaccag ataaatggac tgtttcagga cgtggagaat tgcacttgtc aatccttatc
    41521 gaaacaatgc gtcgtgaggg ctatgaactt caagtatctc gtccagaagt tatcgtaaaa
    41581 gaaatcgacg gtgttaaatg tgaaccattt gaacgtgtac aaatcgacac tccagaagaa
    41641 taccaagggt ctgttatcca aagcctttct gaacgtaaag gtgaaatgtt ggatatgatt
    41701 tcaactggta atggtcaaac tcgtttggtc ttccttgttc cagcgcgtgg tttgattgga
    41761 tactcaactg agttcttgtc aatgactcgt ggttacggta tcatgaacca taccttcgac
    41821 caatacttgc cattgattcc aggggaaatt ggtggacgtc accgtggtgc ccttgtttct
    41881 atcgatgctg gtaaggctac aacttactca atcatgtcta tcgaagaacg tggtacgatc
    41941 tttgtcaacc caggtactga ggtttatgaa ggaatgatca tcggtgaaaa ctctcgtgaa
    42001 aatgacttga cagttaacat cacgaaggca aaacaaatga ccaacgttcg ttcagctact
    42061 aaggaccaaa cagctgttat caagacgcct cgtatcttga cacttgaaga gtctcttgag
    42121 ttcttgaacg acgatgagta catggaagta acgcctgagt ctatccgttt gcgtaaacaa
    42181 atccttaaca aagcagagcg tgagaaagct aacaagaaga aaaaatcagc tgaataagag
    42241 ctagaaagag agaaagatgg tctatttagt cctaggaatt ttactgctcc tactctatgt
    42301 atttgcgaca ccagaaagca ttaaagggac agtcaatatc gtcgctatgg tatgtatttt
    42361 agtggcactc ttgattttat tggttctatc ttttctgaaa atttttcaat taccaacaga
    42421 aatattccta gcaatagcca tgttgatcct agcttacttt agtgttagag acatcacact
    42481 catgccagtc aaaaaaagta aaagaagata aaaaagagag tttcggctct ctttttgcta
    42541 ggaattttat aatagtttga attgcttttt agttaacacc atctcttttg cttgtatagt
    42601 atgaatggga aaaacttgaa taaaattcgt taatggcatc tattttatat ttggttagta
    42661 ctggttgcat at
//
LOCUS       DAVLXH010000013        40253 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00028199
            SAMN33607166-rid17955573.denovo.013, whole genome shotgun sequence.
ACCESSION   DAVLXH010000013 DAVLXH010000000
VERSION     DAVLXH010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607166
            Sequence Read Archive: SRR23725544
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 40253)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40253)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721421.1
            Genome Coverage       :: 115x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:42:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,210
            CDSs (total)                      :: 2,161
            Genes (coding)                    :: 2,023
            CDSs (with protein)               :: 2,023
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 73 of 138
            Pseudo Genes (incomplete)         :: 60 of 138
            Pseudo Genes (internal stop)      :: 40 of 138
            Pseudo Genes (multiple problems)  :: 31 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40253
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607166-rid17955573.denovo.013"
                     /strain="AUSMDU00028199"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1349"
     gene            20..405
                     /locus_tag="VYO11_000763"
                     /pseudo
     CDS             20..405
                     /locus_tag="VYO11_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000769852.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            940..1632
                     /locus_tag="VYO11_000764"
     CDS             940..1632
                     /locus_tag="VYO11_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006703946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate mutase"
                     /protein_id="HEV1595355.1"
                     /translation="MVKLVFARHGESEWNKANLFTGWADVDLSEKGTQQAIDAGKLIK
                     EAGIEFDQAYTSVLKRAIKTTNLALEASDQLWVPVEKSWRLNERHYGGLTGKNKAEAA
                     EQFGDEQVHIWRRSYDVLPPNMDRDDEHSAHTDRRYASLDDSVIPDAENLKVTLERAL
                     PFWEDKIAPALKDGKNVFVGAHGNSIRALVKHIKGLSDDEIMDVEIPNFPPLVFEFDE
                     KLNVVSEYYLGK"
     gene            1685..4096
                     /locus_tag="VYO11_000765"
     CDS             1685..4096
                     /locus_tag="VYO11_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000620712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
                     /protein_id="HEV1595356.1"
                     /translation="MIRNKKQDYVLAYKQPASTTYMGWEEEALPIGNGSLGAKVFGLI
                     GAERIQFNEKSLWSGGPLPDSSDYQGGNLQDQYVFLAEIRQALEKRDYNLAKELAEQH
                     LIGPKTSQYGTYLSFGDIHIEFSQQGTTLSQVTDYQRQLNISKALATTSYVYKGTRFE
                     REAFASFPDDLLVQCFTKEGLETLDFTIELSLTCDLASNGKYEQEKSDYKECKLDITD
                     SHILMKGRVKDNDLRFASYLAWETDGDIRVWSDRVQISGASYANLFLAAKTDFAQNPA
                     SNYRKKLDLEQQVIDLVDTAKEKGYTQLKSRHIEDYQALFQRVQLDLEADVDASTTDD
                     LLKNYKPQEGQALEELFFQYGRYLLISSSRDCPDALPANLQGVWNAVDNPPWNSDYHL
                     NVNLQMNYWPAYVTNLLEAVFPVINYVDDLRVYGRLAAVKYAGIVSQKGEENGWLVHT
                     QATPFGWTAPGWDYYWGWSPAANAWMMQTVYETYSFYRDQDYLREKIYPMLRETVRFW
                     NAFLHKDQQAQRWVSSPSYSPEHGPISIGNTYDQSLIWQLFHDFIQAAQELGLDEDLL
                     TEVKEKSDLLNPLQITQSGRIREWYEEEEQYFQNEKVEAQHRHASHLVGLYPGNLFSY
                     KGQEYIEAARASLNDRGDGGTGWSKANKINLWARLGDGNRAHKLLAEQLKTSTLPNLW
                     CSHPPFQIDGNFGATSGMAEMLLQSHAAYLVPLAALPDAWSTGSVSGLMARGHFEVSM
                     SWEDKKLLQLTILSRSGGDLRVSYPDIEKSVIKMNQEKIKAKCMGKDCISVATAEGDL
                     VQFYF"
     gene            4346..5047
                     /locus_tag="VYO11_000766"
     CDS             4346..5047
                     /locus_tag="VYO11_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1595357.1"
                     /translation="MAYIEMKHCYKRYQVGDTEIVANRDVNFEIEKGELVIILGASGA
                     GKSTVLNLLGGMDTNDEGEIWIDGVNIADYSSHQRTNYRRNDVGFVFQFYNLVSNLTA
                     KENVELASEIVTDALNPDQVLTDVGLAHRLNNFPAQLSGGEQQRVSIARAVAKNPKIL
                     LCDEPTGALDYQTGKQVLKILQDMSRQKGATVIIVTHNGALAPIADRVIHMHDASVKD
                     VVLNQHPQDIDSLEY"
     gene            5049..7757
                     /locus_tag="VYO11_000767"
     CDS             5049..7757
                     /locus_tag="VYO11_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HEV1595358.1"
                     /translation="MIKRKTYWKDLIQSFTGSKGRFLSILILMMLGSLALVGLKVTSP
                     NMEATANAYLTTAQTLDLAVMSNYGLDQADQEELKQTEGAEVEFGYLTDVTMDNGQDA
                     IRLYSKPERISTFQLRKGRLPQSDKEIALATHLQGQYSVGQEISFKEKEEGHSSLKDH
                     TYTITGFVDSAEILSQRDMGYAGSGSGTLTAYGVILPSQFDQKVYNIARLKYQDLAGL
                     NAFSSAYEEKSKQHQEELEQILSDNGKVRLQLLKKEGQESLDKGQETLDKAQTNLQEG
                     KRRLAAAQARIQAQESQLALFPQVQREQASAQLTQAKQELGKEEAKLKQAEQNLAQEN
                     EKLEKHQQVLDDLAEPRYQVYNRQTMPGGQGYLMYSNASSSIRAVGNIFPVVLYAVAA
                     MVTFTTMTRFVDEERTHAGIFKALGYRSKDIIAKFLLYGLVAGTVGTALGSILGHYLL
                     ASVISSVITKGMVVGETQIQFYWTYSLLALVLSLLASVLPAYLVAWRELHDEAAQLLL
                     PKPPVKGAKILLERIGFIWRRLSFTHKVTARNIFRYKQRMLMTIFGVAGSVALLFAGL
                     GIQSSVAGVPSKQFQQIQQYQMLVSENPSATNQDKVELAEVLKGQEILAYQKIYSKTL
                     DKDFKGKAGLQNITLMMIEKEDLTPFIHLQHHQQELTLKDGIVITAKLAQLAGVKVGQ
                     TLEIEGKELKVAAITENYVGHFIYMSQASYEQLYGQLPQANTYLVSLRDTSATSIESQ
                     AGLLMNQSAVSSVVQNASAIRLFDSIASSLNQTMTILVIVSVLLAIVILYNLTNINVA
                     ERIRELSTIKVLGFHNNEVTLYIYRETIVLSLVGIVLGLIAGFYLHQFLIQMISPATI
                     LFYPQVGWEVYVIPVAAVSIILTLLGFFVNYYLRKVDMLEALKSVE"
     gene            complement(7853..8344)
                     /gene="tpx"
                     /locus_tag="VYO11_000768"
     CDS             complement(7853..8344)
                     /gene="tpx"
                     /locus_tag="VYO11_000768"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol peroxidase"
                     /protein_id="HEV1595359.1"
                     /translation="MVTFLGNPVSFTGKQLQVGDKALDFSLTTTDLSKKSLADFDGKK
                     KVLSVVPSIDTGICSTQTRRFNEELAGLDNTVVLTVSMDLPFAQKRWCGAEGLDNAIM
                     LSDYFDHSFGHDYALLINEWHLLARAVFVLDTDNTIRYVEYVDNINSEPNFEAAIAAA
                     KAL"
     gene            complement(8467..9396)
                     /gene="psaA"
                     /locus_tag="VYO11_000769"
     CDS             complement(8467..9396)
                     /gene="psaA"
                     /locus_tag="VYO11_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000733059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding
                     lipoprotein/adhesin PsaA"
                     /protein_id="HEV1595360.1"
                     /translation="MKKLGTLLVLFLSAIILVACASGKKDTTSGQKLKVVATNSIIAD
                     ITKNIAGDKIDLHSIVPIGQDPHEYEPLPEDVKKTSEADLIFYNGINLETGGNAWFTK
                     LVENAKKTENKDYFAVSDGVDVIYLEGQNEKGKEDPHAWLNLENGIIFAKNIAKQLSA
                     KDPNNKEFYEKNLKEYTDKLDKLDKESKDKFNKIPAEKKLIVTSEGAFKYFSKAYGVP
                     SAYIWEINTEEEGTPEQIKTLVEKLRQTKVPSLFVESSVDDRPMKTVSQDTNIPIYAQ
                     IFTDSIAEQGKEGDSYYSMMKYNLDKIAEGLAK"
     gene            complement(9428..10276)
                     /locus_tag="VYO11_000770"
     CDS             complement(9428..10276)
                     /locus_tag="VYO11_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000559784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEV1595361.1"
                     /translation="MIAEFIDGLQKFHFLQNALITAIVVGIVAGAVGCFIILRGMSLM
                     GDAISHAVLPGVALSFILGLDFFIGAIVFGLLAAIIITYIKGNSIIKSDTAIGITFSS
                     FLALGIILIGVAKSSTDLFHILFGNILAVQDTDMFITMGVGAAILLLIWIFFKQLLIT
                     SFDELLAKAMGMPVNFYHYLLMVLLTLVSVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKSMIFLSSTFGATASVLGLFIGYSFNVAAGSSIVLTAASFFLISFFIAPKQRYLKLK
                     NKHLLK"
     gene            complement(10273..10995)
                     /locus_tag="VYO11_000771"
     CDS             complement(10273..10995)
                     /locus_tag="VYO11_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEV1595362.1"
                     /translation="MIRIENLSVSYKETLALKDISLVLHGPTITGIIGPNGAGKSTLL
                     KGMLGIIPHQGQAFLDDKEVKKSLHRIAYVEQKINIDYNFPIKVKECVSLGLFPSIPL
                     FRSLKAKHWKKVQEALEIVGLADYAERQISQLSGGQFQRVLIARCLVQEADYILLDEP
                     FAGIDSVSEEIIMNTLRDLKKAGKTVLIVHHDLSKIPHYFDQVLLVNREVIAFGPTKE
                     TFTETNLKEAYGNQLFFNGGDL"
     gene            11286..13178
                     /gene="pepO"
                     /locus_tag="VYO11_000772"
     CDS             11286..13178
                     /gene="pepO"
                     /locus_tag="VYO11_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase PepO"
                     /protein_id="HEV1595363.1"
                     /translation="MTRYQDDFYDAINGEWQQTAEIPADKSQTGGFVDLDQEIEDLML
                     ATTDKWLAGEEVPEDAILENFVKYHRLVRDFDKREADGITPVLPLLKEFQELETFADF
                     TAKLAEFELAGKPNFLPFGVSPDFMDARINVLWASAPSTILPDTTYYAEEHPQREELL
                     TLWKESSANLLKAYDFSDEEIEDLLEKRLELDRRVAAVVLSNEERSEYAKLYHPYSYE
                     DFKKFAPALPLDDFFKAVIGQLPDKVIVDEERFWQAAEQFYSEEAWSLLKATLILSVV
                     NLSTSYLTEDIRVLSGAYSRALSGVPEAKDKVKAAYHLAQEPFKQALGLWYAREKFSP
                     EAKADVEKKVATMIDVYKERLLKNDWLTPETCKQAIVKLNVIKPYIGYPEELPARYKD
                     KVVNETASLFENALAFARVEIKHSWSKWNQPVDYKEWGMPAHMVNAYYNPQKNLIVFP
                     AAILQAPFYDLHQSSSANYGGIGAVIAHEISHAFDTNGASFDENGSLKDWWTESDYAA
                     FKEKTQKVIDQFDGQDSYGATINGKLTVSENVADLGGIAAALEAAKREADFSAEEFFY
                     NFGRIWRMKGRPEFMKLLASVDVHAPAKLRVNVQVPNFDDFFTTYDVKEGDGMWRSPE
                     ERVIIW"
     gene            complement(13301..13930)
                     /locus_tag="VYO11_000773"
     CDS             complement(13301..13930)
                     /locus_tag="VYO11_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEV1595364.1"
                     /translation="MKIHKTVNPVAYENTYYLEGEKHLIVVDPGSHWEAIRQTIEKIN
                     KPICAILLTHAHYDHIMSLDLVRETFGNPPVYIAESEASWLYTPVDNLSGLPRHDDMA
                     DVVTKPAEHTFVFHEEYQLEEFRFKVLPTPGHSIGGVSLVFPDAYLVLTGDALFRETI
                     GRTDLPTGSMEQLLHSIQTQLFTLPNYDVYPGHGPATTIAHEKAFNPFF"
     gene            14887..17109
                     /locus_tag="VYO11_000774"
     CDS             14887..17109
                     /locus_tag="VYO11_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019316080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HEV1595365.1"
                     /translation="MPKEVNLTGEEVVALTKEYLTEEDVHFVHKALVYAVECHSGQYR
                     KSGEPYIIHPIQVAGILAKLKLDAVTVACGFLHDVVEDTDATLDDLEREFGPDVRMIV
                     DGVTKLGKVEYKSIEEQLAENHRKMLMAMSEDIRVILVKLSDRLHNMRTLKHLRKDKQ
                     ERISKETMEIYAPLAHRLGISSVKWELEDLSFRYLNPTEFYKITHMMKEKRREREALV
                     DEVVTKLEEYTTERHLKGKIYGRPKHIYSIFRKMQDKRKRFEEIYDLIAIRCILDTQS
                     DVYAMLGYVHEFWKPMPGRFKDYIANRKANGYQSIHTTVYGPKGPIEFQIRTKEMHEV
                     AEYGVAAHWAYKKGIKGQVNSKESAIGMNWIKEMMELQDQADDAKEFVDSVKENYLAE
                     EIYVFTPDGAVRSLPKDSGPIDFAYEIHTKVGEKATGAKVNGRMVPLTTKLKTGDQVE
                     IIANPNSFGPSRDWLNMVKTSKARNKIRQFFKNQDKELSVNKGREMLMAQFQENGYVA
                     NKFMDKRHMDQVLQKTSYKTEDSLFAAIGFGEIGAITVFNRLTEKERREEERAKAKAE
                     AEELVKGGEVKVENKETLKVKHEGGVVIEGASGLLVRIAKCCNPVPGDDIVGYITKGR
                     GVAIHRVDCMNLRAQENYEQRLLDVEWEDQYSSSNKEYMAHIDIYGLNRTGLLNDVLQ
                     VLSNTTKNISTVNAQPTKDMKFANIHVSFGIANLSTLTTVVDKIKSVPEVYSVKRTNG
                     "
     gene            17139..17582
                     /locus_tag="VYO11_000775"
     CDS             17139..17582
                     /locus_tag="VYO11_000775"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HEV1595366.1"
                     /translation="MKIIIQRVKKAQVSIEGQIQGKINQGLLLLVGVGPEDQEEDLDY
                     AVRKLVNMRIFSDAEGKMNLSVKDIEGEILSISQFTLFADTKKGNRPAFTGAAKPDMA
                     SDFYDAFNQKLAQEVPVQTGIFGADMQVELVNNGPVTIILDTKKR"
     gene            complement(17819..18035)
                     /locus_tag="VYO11_000776"
                     /pseudo
     CDS             complement(17819..18035)
                     /locus_tag="VYO11_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720032.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(18199..18849)
                     /locus_tag="VYO11_000777"
     CDS             complement(18199..18849)
                     /locus_tag="VYO11_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000188500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HEV1595367.1"
                     /translation="MTPNKEDYLKCIYEIGIDLHKITNKEIAARMQVSPPAVTEMIKR
                     MKSENLILKDKECGYLLTDLGLKLVSELYRKHRLIEVFLVHHLDYTSDQIHEEAEVLE
                     HTVSDLFVERLDKLLGFPKTCPHGGTIPAKGELLVEINNLPLADIKEAGAYRLTRVHD
                     SFDILHYLDKHSLHIGDQLQVKQFDGFSNTFTILSNDEDLQVNMDIAKQLYVEKIN"
     gene            18961..19803
                     /locus_tag="VYO11_000778"
                     /pseudo
     CDS             18961..19803
                     /locus_tag="VYO11_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862319.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
     gene            19879..20316
                     /locus_tag="VYO11_000779"
     CDS             19879..20316
                     /locus_tag="VYO11_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HEV1595368.1"
                     /translation="MQIPSRFTIATHMLIIIALEGKESKVTSDFLAASVGVNPVIIRN
                     ILSQLKKAELISVARGTGGTEIVKDLKDISLLDVYQAVECLGKTGQLFSFHDNPNPNC
                     PVGAHIHDVLDQKLERIQLTMEAELGQTSLEKVVADAESQMKD"
     gene            20384..20635
                     /locus_tag="VYO11_000780"
     CDS             20384..20635
                     /locus_tag="VYO11_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000281600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1595369.1"
                     /translation="MYLVIGIVLAFIVSFWKDNRSLWNPVLFLLSLISSYFYLSYLFY
                     KNGYENVQLAFYVFTFVLLPFLLFLSGIFLIYNGVILLK"
     gene            complement(20777..21850)
                     /locus_tag="VYO11_000781"
     CDS             complement(20777..21850)
                     /locus_tag="VYO11_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2974 domain-containing protein"
                     /protein_id="HEV1595370.1"
                     /translation="MANIFDYLKDVAYDSYYDLPLNELDILTLIEITYLSFDNLVSTL
                     PQRLLELAPQVPREPTMLTSKNRLQLLDELAQHKRFKNCKLSHFINDIDPELQKQFAA
                     MTYRVSLDTYLIVFRGTDDSIIGWKEDFHLTYMKEIPAQKHALRYLKNFFAHHPKQKV
                     ILAGHSKGGNLAIYAASQIEQSLQNQITAVYTFDAPGLHQELTQTAGYQRIMDRSKIF
                     IPQGSIIGMMLEIPAHQIIVQSTALGGIAQHDTFSWQIEDKHFVQLDKTNSDSQQVDT
                     TFKEWVATVPDEELQLYFDLFFGTILDAGISSINDLASLKALEYIHHLFVQAQSLTPE
                     ERETLGRLTQLLIDTRYQAWKNR"
     gene            22006..22683
                     /locus_tag="VYO11_000782"
     CDS             22006..22683
                     /locus_tag="VYO11_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000548969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1595371.1"
                     /translation="MHKILLVEDDQVIRQQVGKMLSEWGFEVVLVEDFMEVLSLFVQS
                     EPHLVLMDIGLPLFNGYHWCQEIRKISKVPIMFLSSRDQAMDIVMAINMGADDFVTKP
                     FDQQVLLAKVQGLLRRSYEFGRDESLLEYAGVILNTKSMDLHYQGQVLNLTKNEFQIL
                     RVLFEHAGNIVARDDLMRELWNSDFFIDDNTLSVNVARLRKKLEEQGLVGFIETKKGI
                     GYGLKHA"
     gene            22676..23650
                     /locus_tag="VYO11_000783"
     CDS             22676..23650
                     /locus_tag="VYO11_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEV1595372.1"
                     /translation="MLDWKQFFLAYLRSRSRLFVYLLSLAFLVLLFQFLFASLGIYFL
                     YFFLLCCFVTILFFTWDILVEMQVYRQELLYGEREAKSPLEIALAEKLEAREMELYQQ
                     RSKAERKLTDLLDYYTLWVHQIKTPIAASQLLVAEVVDRQLKQQLEQEIFKIDSYTNL
                     VLQYLRLESFHDDLLLKQVQIEDLVKEIIRKYALFFIQKGLNVNLHDLDKEIVTDKKW
                     LLVVIEQIISNSLKYTKEGGLEIYMDDQELCIKDTGIGIKNSDVLRVFERGFSGYNGR
                     LTQQSSGLGLYLSKKISEELGHQIRIESEVGKGTTVRIQFAQVNLVLE"
     gene            complement(23699..25642)
                     /gene="thrS"
                     /locus_tag="VYO11_000784"
     CDS             complement(23699..25642)
                     /gene="thrS"
                     /locus_tag="VYO11_000784"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HEV1595373.1"
                     /translation="MINITFPDGAVREFESGVTTFEIAQSISNSLAKKALAGKFNGKL
                     IDTTRAITEDGSIEIVTPDHEDALPILRHSAAHLFAQAARRLFPDIHLGVGPAIEDGF
                     YYDTDNTAGQISNEDLPRIEEEMQKIVKENFPSIREEVTKDEAREIFKNDPYKLELIE
                     EHSEDEGGLTIYRQGEYVDLCRGPHVPSTGRIQIFHLLHVAGAYWRGNSDNAMMQRIY
                     GTAWFDKKDLKNYLQMREEAKERDHRKLGKELDLFMISQEVGQGLPFWLPNGATIRRE
                     LERYIVNKELASGYQHVYTPPLASVELYKTSGHWDHYQEDMFPTMDMGDGEEFVLRPM
                     NCPHHIQVFKHHVHSYRELPIRIAEIGMMHRYEKSGALTGLQRVREMSLNDGHLFVTP
                     EQIQEEFQRALQLIIDVYEDFNLTDYRFRLSLRDPQDTHKYFDNDEMWENAQTMLRAA
                     LDEMGVDYFEAEGEAAFYGPKLDIQIKTALGKEETLSTIQLDFLLPERFDLKYIGADG
                     EDHRPVMIHRGVISTMERFTAILIENYKGAFPTWLAPHQVTLIPVSNEKHVDYAWEVA
                     KKLRDRGVRADVDERNEKMQFKIRASQTSKIPYQLIVGDKEMEDETVNVRRYGQKETQ
                     TVSVDNFVQAILADIANKSRVEK"
     gene            complement(25700..25876)
                     /locus_tag="VYO11_000785"
     CDS             complement(25700..25876)
                     /locus_tag="VYO11_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like protein"
                     /protein_id="HEV1595374.1"
                     /translation="MTKQGRYYDETPYTLEQKLSENIWWLLELSQRLDIDILTEMKNF
                     LSDKEKQLNVRTRK"
     gene            complement(25883..26023)
                     /locus_tag="VYO11_000786"
     CDS             complement(25883..26023)
                     /locus_tag="VYO11_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000422774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like protein"
                     /protein_id="HEV1595375.1"
                     /translation="MELQELVERSWAIRQAYHELEVKHHDFKWTVEEDLLALSNDIGN
                     FQ"
     gene            26893..27522
                     /locus_tag="VYO11_000787"
     CDS             26893..27522
                     /locus_tag="VYO11_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HEV1595376.1"
                     /translation="MKLAVIAANGQAGKAIVEEAVKRGHEVTAIVRSENKSQAESIIK
                     KDLFELTKDDLTGFDAVISAFGAYTPDTLPLHSKSIELFNQLLAGTQTRFLVVGGAGS
                     LYIDETKTTRLLDTSDFPEEFKSLAKAQADELDLLRTKNNLNWTFVSPAVDFIPDGEK
                     TGNYILAGEIFTTNEKGISQISYADYAIGLVDELEKGHHIKERISLLEK"
     gene            27663..27932
                     /gene="rpsO"
                     /locus_tag="VYO11_000788"
     CDS             27663..27932
                     /gene="rpsO"
                     /locus_tag="VYO11_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HEV1595377.1"
                     /translation="MAISKEKKNEIIAQYARHEGDTGSVEVQVAVLTWEINHLNEHIK
                     QHKKDHATYRGLMKKIGRRRNLLAYLRKNDVNRYRELINSLGLRR"
     gene            28746..29360
                     /locus_tag="VYO11_000789"
     CDS             28746..29360
                     /locus_tag="VYO11_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000531723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CadD family cadmium resistance transporter"
                     /protein_id="HEV1595378.1"
                     /translation="MGQTIISAIGVYISTSIDYLIILIILFAQLSQNKQKWHIYAGQY
                     LGTGLLVGASLVAAYVVNFVPEEWMVGLLGLIPIYLGIRFAIVGEDAEEEEEEIIERL
                     EQSKANQLFWTVTLLTIASGGDNLGIYIPYFASLDWSQTLVALLVFVIGIIIFCEISR
                     VLSSIPLIFETIEKYERIIVPLVFILLGLYIMYENGTIETFLIV"
     gene            complement(29653..30402)
                     /locus_tag="VYO11_000790"
     CDS             complement(29653..30402)
                     /locus_tag="VYO11_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HEV1595379.1"
                     /translation="MFYTYLRGLVVLLLWSINGNAHYHNTDKIPNQDENYILVAPHRT
                     WWDPVYMAFATKPKQFIFMAKKELFTNRIFGWWIRMCGAFPIDRENPSASAIKYPINV
                     LKKSDRSLIMFPSGSRHSNDVKGGAALIAKMAKVRIMPVTYTGPMTLKGLISRERVDM
                     NFGNPIDISDIKKMNDEGIETVANRIQTEFQRLDEETKQWHNDKKPNPLWWFIRIPAL
                     ILAIILAILTIIFSFIASFIWNPDKKREELA"
     gene            30535..32871
                     /locus_tag="VYO11_000791"
     CDS             30535..32871
                     /locus_tag="VYO11_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
                     /protein_id="HEV1595380.1"
                     /translation="MDKNKIMGLTQREVKERQAEGLVNDFTASASTSTWQIVKRNVFT
                     LFNALNLAIALALAFVQAWSNLVFFAVICFNAFSGIVTELRAKHMVDKLNLMTKEKVK
                     TIRDGQEVALNPEELVLGDVIRLSAGEQIPSDALVLEGFAEVNEAMLTGESDLVQKEV
                     DGLLLSGSFLASGSVLSQVHHVGADNYAAKLMLEAKTVKPINSRIMKSLDKLAGFTGK
                     IIIPFGLALLLEALLLKGLPLKSSVVNSSTALLGMLPKGIALLTITSLLTAVIKLGLK
                     KVLVQEMYSVETLARVDMLCLDKTGTITQGKMQVEAVLPLTETYGEEAIASILTSYMA
                     HSEDKNPTAQAIRQRFVGDVAYPMISNLPFSSDRKWGAMELEGLGTVFLGAPEMLLDS
                     EVPEAREALERGSRVLVLALSQEKLDHHKPQKPSDIQALALLEILDPIREGAAETLNY
                     LRSQEVGLKIISGDNPVTVSSIAQKAGFADYHSYVDCSKITDEELIALAEETAIFGRV
                     SPHQKKLIIQTLKKAGHTTAMTGDGVNDILALREADCSIVMAEGDPATRQIANLVLLN
                     SDFNDVPEILFEGRRVVNNIAHIAPIFLIKTIYSFLLAVICIASALLGRSEWILIFPF
                     IPIQITMIDQFVEGFPPFVLTFERNIKPVEPNFLRRSMLRALPSALMVVFSVLFVKIF
                     GTSQGWSELEISTLLYYLLGSIGFLSVFRACMPFTLWRVLLIVWSVGGFLATALFPRI
                     QKLLEIATLTGQTLPVYGVMMLVFTVIFILTSRYQEKK"
     gene            33400..34863
                     /locus_tag="VYO11_000792"
     CDS             33400..34863
                     /locus_tag="VYO11_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000087917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HEV1595381.1"
                     /translation="MSRKQEQMETLLLLLRDSKDYISAKVLGEKLNCSDKTVYRLVKG
                     INKDCPVEAFILSEKGRGFKLNPRSSLVDVDGNFTEAFDPEVRREKLLERLLLTAPKP
                     HSIYDLGEEFYVSESVVLKDRQILQESLAIYGLDLKMRQRKLFIDGDEAQIRSAILNL
                     LPMFNQLDLEQITQNKVQPLDGELAHFCLGLLITLERELGVNIPYPYNINIFSHLYIF
                     ISRNRRSTSIHVVAPSKPTIVDEKIYSVCQKIIQEIEQYFRMKVDAVEIDYLYQYVVS
                     SRLQKPFSSGKLPFSQRVLDVTHYYFSRMCMDNREIETTDPDFVDLASHISPLLRRLD
                     NRVQIKNSLLSQILLTYPNLVKELTTISKEVSLVFGFASLSLDEIGFLVLYFARFQEK
                     RARPLKTVVMCTSGVGTSELLRARLEKQFSELDIIDVVAYHQLDELINLYPDLDFIVT
                     TVALQEPASVPFVLVSVFLTEGDKQRLQAKIQEINYE"
     gene            34856..35284
                     /locus_tag="VYO11_000793"
     CDS             34856..35284
                     /locus_tag="VYO11_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV1595382.1"
                     /translation="MNNLSLVLMDISVQNRQEAYKELANQISLLVSEDTEKIEELLYY
                     RERQGSIEVAKGVLLPHCEGNFQHHVLVITRLKPPIREWSKDIQCVDLIIGLAIAVSQ
                     DKSCIKTLMRRLADESFINQLKQLTKEELREIIYGNQRYS"
     gene            35262..35711
                     /locus_tag="VYO11_000794"
     CDS             35262..35711
                     /locus_tag="VYO11_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV1595383.1"
                     /translation="MEIKDILNVSLIQTDLQMQSKEEVFEALAQLLVETGYVSDRDQF
                     IEGLYQREAEGQTGIGNYIAIPHSKSSAVEKAGVVIAINHNEIPWETIDGKGVKVIVL
                     FAVGDDTEAAREHLKTLSLFARKLGNDEVVAKLVRAQTSDDVIAAFC"
     gene            35739..36050
                     /locus_tag="VYO11_000795"
     CDS             35739..36050
                     /locus_tag="VYO11_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HEV1595384.1"
                     /translation="MKIVGVAACTVGIAHTYIAQEKLENAAKVAGHVIHVETQGTIGV
                     ENELSQEQIDAADVVILAVDVKISGMERFEGKKIIKVPTEVAVKSPNKLIAKAVEIVT
                     K"
     gene            36076..37161
                     /locus_tag="VYO11_000796"
     CDS             36076..37161
                     /locus_tag="VYO11_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000912151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HEV1595385.1"
                     /translation="MLKHLNLKGHLLTAISYMIPIVCGAGFLVAIGLAMGGGVPDALV
                     AGKFTIWDALATMGGKALGLLPVVIATGLSYSIAGKPGIAPGFVVGLIANSVGSGFIG
                     GILGGYIAGFLVQAIIKKVKVPNWIKGLMPTLIIPFVASLVSSLIMIYIIGAPIAAFT
                     NWLTSLLQSLGSASNGLMGAVIGVLSAVDFGGPLNKTVYAFVLTLQAEGVKEPLTALQ
                     LVNTATPVGFGLAYFIAKLLKKNIYTQEEIETLKSAVPMGIVNIVEGVIPIVMNNLVP
                     GLIATGIGGAVGGAVSLTMGADSAVPFGGVLMLPTMTRPVAGICALLANIVVTGLVYA
                     ILKKPIKHTEPVMTVEEEIDLSDIEIL"
     gene            37172..37867
                     /locus_tag="VYO11_000797"
     CDS             37172..37867
                     /locus_tag="VYO11_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000086495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HEV1595386.1"
                     /translation="MSRIEFSPSLMTMDLDKFKEQITFLNDKVASYHIDIMDGHFVPN
                     ITLSPWFIQEVQKISDTPLSVHLMVTDPTFWVDQVLDLQCEYICIHAEVLNGLAFRLI
                     DKIHDAGLKAGVVLNPETPVSTIFPYIDLLDKVTIMTVDPGFAGQRFLESTLYKIQEL
                     RQLRVQNGYHYIIEMDGSSSRKTFKQIDVAGPDIYVIGRSGLFGLDDDIAKAWDICSR
                     DYEEMTGKTMPIK"
     gene            37904..39874
                     /gene="tkt"
                     /locus_tag="VYO11_000798"
     CDS             37904..39874
                     /gene="tkt"
                     /locus_tag="VYO11_000798"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HEV1595387.1"
                     /translation="MSLQSVNAIRFLGVDAINKSNSGHPGIVMGAAPMAYSLFTKHLR
                     ITPEQPNWINRDRFILSAGHGSMLLYALLHLTGYNDVSMDEIKNFRQWGSKTPGHPEV
                     THTSGVDATSGPLGQGISTAVGFAQAERFLAAKYNKDGFPIFDHYTYVIAGDGDFMEG
                     VSAEAASYAGHQALDKLIVLYDSNDICLDGETKDTFSENVRARYDAYGWHTVLVEDGT
                     DLAAISTAIETAKFSGKPSLIEVKTVIGYGSPNKSGTNAVHGAPLGAEETGATRKFLG
                     WDYDPFEVPEEVYSDFKTNVADRGQEAYDAWASLVSDYKVAYPEVASEIDAIVAGKSP
                     VTITEKDFPVYENGFSQATRNSSQDAINTAAAVLPTFLGGSADLAHSNMTYIKADGLQ
                     DKYNPLNRNIQFGVREFAMGTILNGMALHGGLRVYGGTFFVFSDYIKAAIRLSAIQEL
                     PVTYVFTHDSIAVGEDGPTHEPVEHLAGLRSMPNLTVIRPADARETQAAWHHALTSTT
                     TPTVIVLTRQNLVVEEGTDFGKVAKGAYVVYDTPGFDTIIIATGSEVNLAIKAAKELV
                     LQGGKVRVVSMPSTELFDAQDATYKEDILPSKTRRRVAIEMAATQSWYKYVGLDGAVI
                     GIDIFGASAPAQTVIDNYGFTVENIVAQVKSL"
BASE COUNT        11717 a         7383 c         9158 g        11995 t
ORIGIN      
        1 taaaaaagga gattttatta tgaaattaaa aacacttgct ttaattagtg gtatcgtcgg
       61 tcttgtggga ggaattttac ttcttattgg tccttttgtc ttgttgggaa cagcggtaaa
      121 cacagctgct acaactctta atggaggagc tactgcaggg gctttttcag gtgttgcctt
      181 actcttgaat gccttgaaga ttgcaaatct tgttcttggt atcattgcta ttgtttacta
      241 taaaggagat aagcgtgtag gtgcagctcc gtctgtacta atgattgttt ctggtggagt
      301 tagtctcatt ctattccgtt cttaggatgg gttgggggga ttcttgctat tatcggagga
      361 tctctattcc tttcaacatt gaagaaattc aaatcagaag aataaaaggt attttagcat
      421 gaaaagaaca aaaaagttta tcggtatagg agtagctcta ttatctcttt ctcttctagt
      481 tgcatgtgga acataaagtt caaagaatac ttcaacaagt aatgatgaga agacagtagc
      541 aacatccaat agttcaaaag aaacaatcac tttcgatata ccggttgtaa cagacgatgc
      601 gattgaatca atacgcactt atgcagatta tatagatctt tataaaaata tttttgatga
      661 ttattttact aaagctgagg aaggtttcaa aggcacagct atggaaaata atgactcgtt
      721 tactaaacta aaagagtcaa ctcaaaaatt attcgatgcg cagaaaaaaa ggttaaataa
      781 tgaagataga atagaaacag ccaaaaacaa tgtgattgcc aaacattgtc aaacagtcct
      841 ttcctttttg gttttgacta gcttttttgt gaaaaattgt gtaaaataga atagataaac
      901 gaggggaaac ctcggaaaat ttaaaggaga atccatctaa tggtaaaatt ggtttttgct
      961 cgccacggtg agtctgaatg gaacaaagct aaccttttca ctggttgggc tgatgttgat
     1021 ttgtctgaaa aaggtacaca acaagcgatt gacgctggta aattgatcaa agaagctggt
     1081 atcgaatttg accaagctta cacttcagta ttgaaacgtg ctatcaaaac aactaacttg
     1141 gctcttgaag cttctgacca attatgggtt ccagttgaaa aatcatggcg cttgaacgaa
     1201 cgtcactacg gtggtttgac tggtaaaaac aaagctgaag ctgctgaaca atttggtgat
     1261 gagcaagttc acatctggcg tcgttcatac gatgtattgc ctccaaatat ggaccgtgat
     1321 gatgagcact cagctcacac agaccgtcgt tacgcttcac ttgacgactc agttatccca
     1381 gatgctgaaa acttgaaagt gactttggaa cgtgctcttc cattctggga agataaaatc
     1441 gctccagctc ttaaagatgg taaaaacgta ttcgtaggag ctcacggtaa ctcaatccgt
     1501 gcccttgtaa aacacatcaa aggtttgtca gatgacgaga tcatggacgt ggaaatccct
     1561 aacttcccac cattggtatt cgaattcgac gaaaaattga acgtcgtttc tgaatactac
     1621 cttggaaaat aaaaaattgt aagtctagaa ttgatttcta ggctttttat gttagtatgg
     1681 aagtatgata aggaataaaa aacaagatta tgtactggcc tacaagcaac cagcttcaac
     1741 cacttacatg ggttgggaag aagaagcttt accgataggc aatggttctt taggagcaaa
     1801 agtatttggc cttatagggg ctgaacggat tcaatttaat gaaaaaagtc tctggtctgg
     1861 aggtccactt cctgatagtt cagattatca gggtggaaat cttcaggatc agtatgtttt
     1921 tttagctgag attcggcagg ctttggagaa gagagattac aatctggcta aggaactggc
     1981 tgagcagcac ctaattgggc caaaaacgag tcaatatggg acctatctgt cttttgggga
     2041 tattcacatt gagttcagcc agcaaggtac gactttgtct caggtgacgg actatcagag
     2101 acagctgaat attagtaagg cacttgcgac gacttcttat gtctataagg gaacgcgatt
     2161 tgaacgtgaa gcttttgcga gttttccaga tgatctcttg gttcaatgtt ttactaagga
     2221 agggttggaa actctagatt ttactataga actatccttg acctgtgatt tggcttctaa
     2281 tggaaagtat gagcaggaaa aatctgatta caaggagtgt aagttggata ttactgattc
     2341 tcatatcttg atgaagggaa gagttaagga taatgatctg cggtttgcta gttatctagc
     2401 ttgggaaacg gatggagata ttagagtttg gtcagatagg gttcagatat caggagccag
     2461 ttatgccaat ctcttcttgg ccgctaagac ggattttgcc caaaatcctg ctagcaatta
     2521 tcgcaagaaa ctagatttag agcaacaggt gatagacttg gtggacacag ctaaagaaaa
     2581 gggctatacc caattgaaat caaggcatat cgaggactac caagccttat tccagcgtgt
     2641 tcaattggat ttggaagctg atgttgacgc atccactaca gatgatttgt taaaaaatta
     2701 taagccacaa gaagggcagg ctttggagga gctgttcttc cagtatggac ggtatttatt
     2761 gattagttcg tccagagact gcccagatgc tctaccagct aacctacagg gagtctggaa
     2821 tgcagtcgac aatcctcctt ggaattcgga ctatcactta aatgtcaatc tgcagatgaa
     2881 ttattggcca gcctatgtta ccaatctcct agaggcggtc tttccggtca tcaactatgt
     2941 agatgatttg cgtgtctatg gtcgtctagc ggctgtaaag tatgcaggaa tcgtctctca
     3001 gaaaggtgag gagaatggtt ggttggttca tactcaagcg actccctttg gttggacggc
     3061 acctggttgg gattactatt ggggttggtc accagctgcc aatgcgtgga tgatgcaaac
     3121 cgtttatgaa acctattcat tttataggga ccaagactat ctcagggaga aaatttatcc
     3181 catgttgagg gaaacggttc gtttttggaa tgccttttta cataaggatc agcaggcgca
     3241 gcgttgggtg tcttctccgt cttattcccc agaacatggg ccgatttcga ttggcaatac
     3301 ctatgaccaa tctctgattt ggcagttatt tcatgatttt attcaggctg ctcaggaatt
     3361 gggactggat gaggacttgt tgactgaggt taaggagaag tctgatttac taaatccttt
     3421 gcaaatcact caatctggtc gaatcaggga gtggtatgag gaggaagagc agtattttca
     3481 aaatgagaaa gtggaggccc agcatcggca cgcttcccat ctagtgggac tctatcctgg
     3541 caatctcttt agctacaagg gacaagagta tattgaagcg gcgcgtgcta gcctcaatga
     3601 tcgtggagat ggcggcacag gctggtccaa ggctaataag atcaatctct gggcgcgttt
     3661 gggagatggt aatcgagccc ataaattatt ggcagagcag ttaaagacat ccaccttgcc
     3721 aaatctttgg tgtagccatc ctccttttca gatagatggt aattttggtg ctactagtgg
     3781 catggcagaa atgttactcc agtctcatgc agcttatctg gtacctctag ctgccttacc
     3841 tgatgcttgg tcaacaggtt ctgtttcagg cttaatggca cgtggacatt ttgaagtgag
     3901 catgagctgg gaagataaaa aactcttaca gttgaccatt ttatcaagga gtggaggaga
     3961 tttgcgagtt tcttatccag atattgagaa gagtgtgatt aaaatgaatc aagaaaaaat
     4021 aaaagcgaaa tgcatgggga aagattgtat ttcggtggca acagcagaag gtgatcttgt
     4081 tcaattttat ttttaagaag atgttataag gcagtaattt gaaactgcct tttaataagg
     4141 atttaagaat gtaagcagtt tccaactagt tgaaaaagcg ttataatgat aataggaagt
     4201 aatactcaat gaaaatcaaa gagcacaaac taggaagcta gccgcaggtt gctcaaaaca
     4261 gtgttttgag gttgcagatg gaagctgacg tggtttgaag agagattttc gaggagtata
     4321 atttgtttga tagagggtgg gtctgatggc ttatattgag atgaaacact gttacaagcg
     4381 ttatcaggtt ggggacacgg agattgtggc caatcgtgat gtgaattttg agattgaaaa
     4441 gggggagctg gttattatcc ttggtgcttc aggtgcaggt aagtcaacag ttcttaacct
     4501 tcttggggga atggatacca atgatgaagg ggaaatctgg attgatggtg ttaatattgc
     4561 ggattatagt tcccaccagc gcaccaatta ccgtagaaat gatgtggggt ttgtttttca
     4621 gttttataat ctagtttcta atctgacagc taaggaaaat gtggaattgg cttctgaaat
     4681 tgtgacagat gccttgaatc ctgatcaggt cttgacagat gtaggtctgg ctcatcgtct
     4741 caataacttt ccagcccagc tttctggagg ggagcaacag cgagtctcca ttgcacgcgc
     4801 ggtagccaaa aatcctaaaa ttcttctttg tgatgaacct actggagcct tggattatca
     4861 gacgggcaag caggttttga aaattctcca agatatgtct cgtcaaaagg gagcgacggt
     4921 gatcatcgtg actcataatg gagctttggc gcccattgct gatcgcgtga ttcatatgca
     4981 cgatgccagt gtcaaggatg tggtgctcaa ccagcatcct caggatattg acagtttgga
     5041 gtactagtat gatcaagcga aaaacttatt ggaaggactt aattcagtcc ttcacaggct
     5101 ccaaggggcg ttttttatcc atcttgatcc tgatgatgtt gggatctcta gccttagtag
     5161 gcctcaaagt aaccagtccc aacatggagg cgacagctaa tgcttattta acaactgctc
     5221 aaaccttgga tttggcagtc atgtctaact atggcttgga tcaagcagac caagaagaac
     5281 taaaacagac ggagggcgca gaggtcgagt ttggctattt gacagatgtg actatggata
     5341 atgggcagga tgccattcgg ctgtactcca aaccagagcg aatttcaacc tttcagctaa
     5401 gaaagggacg acttcctcag tcagacaagg aaatcgcttt ggccactcat ttgcaaggcc
     5461 aatacagcgt gggacaggag attagtttta aagaaaaaga agagggtcat tcctctttaa
     5521 aagaccatac ttataccatt actggttttg tggattcggc tgaaatcctc tcccagcgag
     5581 atatgggcta cgcaggaagt ggaagtggga ctctgacagc ctatggggtg attttaccta
     5641 gtcagtttga tcagaaagtc tacaatatag ctcgtttgaa atatcaagat ttagcaggtt
     5701 taaatgcctt ttcatcagct tatgaagaaa aatccaagca acatcaggaa gagcttgaac
     5761 aaattttatc agataatggc aaggtacgtc tgcaactttt gaaaaaagaa ggacaagagt
     5821 ctctagacaa ggggcaagag acccttgaca aggctcagac taatttgcag gaaggcaagc
     5881 gtcgtttagc agctgctcaa gctcgtatac aggctcaaga aagtcaacta gccttgtttc
     5941 ctcaagttca gagagagcag gctagtgctc aacttaccca agccaagcag gaattgggca
     6001 aggaagaggc caaactaaag caagctgaac aaaatctagc ccaagaaaat gaaaaattag
     6061 aaaaacatca gcaagtcttg gacgatttgg cggagccaag gtatcaggtc tataatcgtc
     6121 agaccatgcc aggtggtcag ggctatctta tgtatagcaa tgcttcatcc agtattcgag
     6181 cagtgggcaa tatctttcct gtggtacttt atgccgtagc agccatggtg acctttacga
     6241 ccatgactcg ctttgtagac gaagagcgaa ctcatgcagg gatttttaag gccttgggtt
     6301 atcgtagtaa ggatattatc gccaagtttc tcctttatgg actagtagct gggactgtcg
     6361 gaacggctct aggtagtata cttggtcatt atttgctagc cagtgtaatt tcaagtgtca
     6421 ttacaaaagg catggtggtg ggagaaactc agattcagtt ctattggacc tatagcttac
     6481 tagctcttgt cttgagcttg ttggcgagtg tgttaccagc ctatctggtg gcttggaggg
     6541 aacttcatga cgaagcagcc cagcttctac ttcctaaacc tcctgtcaaa ggagctaaaa
     6601 tcttattgga gcgtatcggt tttatctggc gtcgtctcag ttttactcat aaggtaacag
     6661 cccgcaacat ctttcgttat aagcagagaa tgttgatgac aatctttggt gtggcaggtt
     6721 ctgtagctct gctctttgca ggtttgggaa tccaatcttc tgtagcagga gttccgtcta
     6781 aacagtttca acaaatccaa cagtatcaga tgcttgtctc tgaaaatcct agtgcgacca
     6841 atcaggacaa ggtagagcta gcagaagtgt tgaaagggca ggagatacta gcctaccaga
     6901 aaatctattc taaaacgcta gacaaggatt tcaaaggcaa ggctggtctt caaaacatta
     6961 ctcttatgat gatagagaag gaagatttga ctccctttat ccatcttcaa catcatcagc
     7021 aggagctgac attaaaagat ggcatcgtta ttacagctaa actcgcccag ctggcaggtg
     7081 tcaaggttgg gcagacttta gaaattgaag gtaaggaact aaaggtcgct gctattactg
     7141 agaactacgt tggtcacttt atttatatga gtcaggctag ctatgagcaa ctttacggac
     7201 agctacccca agccaacact tatctggtct cattaaggga taccagtgca actagtatcg
     7261 aaagtcaggc gggcttgctt atgaatcaat ctgcggtgtc cagcgttgtc caaaatgctt
     7321 cagccattcg actcttcgac tctatcgcta gctcacttaa tcagaccatg accatcttgg
     7381 tcatcgtatc tgttctatta gctattgtca tcctttacaa tctgaccaat atcaacgtag
     7441 ctgagagaat ccgtgaactc tccactatca aggttctcgg ttttcataat aatgaagtca
     7501 cactctacat ttaccgtgag acgattgtgc tgtcccttgt gggaatcgta cttggtctga
     7561 tagctggttt ctatttacac caatttttga ttcaaatgat ttcgcctgcg actattctct
     7621 tttatccgca ggtaggctgg gaagtctatg taatcccagt ggcagcagta agcatcattt
     7681 tgaccttgct tggtttcttc gtcaattatt atctgagaaa ggttgatatg ttagaagctc
     7741 tgaaatctgt agagtaaggt agttattttt agctgattga acttctattt actaatattc
     7801 aaaaatcctc cgtttcaaag agcagggaac tctttgtgac agaggatttt ttctataggg
     7861 ctttagcagc tgcaattgcg gcttcgaagt ttggctcaga attgatatta tccacgtatt
     7921 caacgtagcg aatcgtattg tcagtatcga ggacaaagac tgcgcgtgct aataggtgcc
     7981 attcgttgat taagagggca taatcgtgcc cgaaagaatg gtcaaagtag tctgaaagca
     8041 taatggcatt gtcaaggcct tcagcaccgc accaacgttt ttgagcaaaa ggtaggtcca
     8101 ttgaaacagt caatacgacc gtgttgtcca gtccagccaa ttcttcatta aaacgacgtg
     8161 tttgagttga gcagatgcct gtatcgatag aaggaacgac actcaagact tttttcttgc
     8221 catcaaaatc agccagagat tttttagaaa gatctgttgt agtaagagaa aaatcaagcg
     8281 ccttgtcgcc aacttgtagt tgtttacctg taaagctcac aggatttccg agaaaagtta
     8341 ccataggata ctccaatctt ttttcttcca ttgtatctga aacagtcaga attttccaat
     8401 gatttgaccg gaaatgtggg catagaaaaa acgccagctc acatgagaat gacgtttttc
     8461 agaggcttat tttgccaatc cttcagcaat cttgtcaagg ttgtatttca tcatgctgta
     8521 gtagctgtcg ccttctttac cttgttctgc gatagagtca gtaaagattt gtgcgtagat
     8581 tgggatgttt gtgtcttgag aaacagtttt cattggacgg tcatccacac ttgattctac
     8641 aaagagtgat ggaacttttg tttggcgaag tttttcaacc aaggtcttga tttgttcagg
     8701 agttccttct tcttcagtat tgatttccca gatgtaggca cttgggacac cataggcttt
     8761 agagaagtat ttgaatgctc cttcgctggt tacaatgagt ttcttttcag cagggatctt
     8821 attaaattta tccttacttt ctttatcaag tttgtctaac ttatcagtat attctttgag
     8881 atttttttca tagaattctt tattgttagg gtctttggcg ctcaattgtt tggcgatatt
     8941 tttagcaaaa ataataccgt tttcaaggtt aagccaagcg tgtgggtctt cttttccttt
     9001 ttcattttga ccttcaaggt agataacatc aacgccgtcg ctgactgcga agtagtcttt
     9061 gttttcagtt ttcttggcat tttctaccaa ttttgtaaac caagcattgc cacctgtttc
     9121 aaggttgata ccgttataga aaatcaaatc agcctcagaa gttttcttaa cgtcttcagg
     9181 aagtggttcg tattcgtgtg ggtcttgccc aatcggaacg atactatgaa ggtcaatttt
     9241 gtcaccagca atatttttag taatatcagc gatgattgag tttgtagcaa caacttttag
     9301 tttttgacca gaagttgtat ctttttttcc gctagcacat gctacaagaa tgattgcaga
     9361 aagaaagaga acgagtaatg tacctaattt tttcattaga tcctccaatt tattagggct
     9421 ttgcccctta ttttaacaaa tgtttatttt tcagtttcaa atatcgttgt ttgggagcga
     9481 taaagaagct aatgagaaag aaactagcag ctgtaagcac gatactagaa cctgccgcaa
     9541 cattaaaact atagccaata aagagtccca aaactgaagc agtagctccg aaggttgagg
     9601 aaaggaaaat catacttttc agactattag catacagata agcagttgca gctggggtaa
     9661 tcagcatggc tacaatcagg atagttccga cactttgcat ggctgtcaca gacacgagag
     9721 tcaggagtac catgagaagg tagtgataga aattgacagg cattcccatg gctttagcca
     9781 agagttcatc aaaggaagtt atcaagagtt gcttgaagaa aatccaaatt aacaagagga
     9841 tggctgcccc cacacccata gtaataaaca tatccgtatc ttggacggcc aggatattac
     9901 caaaaaggat atggaaaagg tcagttgaac ttttagcgac accaatcaag atgataccga
     9961 gggctaagaa agaagaaaag gtaatgccga tggcggtatc gcttttgata atcgagtttc
    10021 ctttgatgta ggtaatgatg atggcagcta gcaatccaaa gacaatggct ccgataaaga
    10081 agtcaaggcc caagatgaag gagagggcta cacctggtaa gacagcatgt gaaatggcat
    10141 ctcccatgag tgacatcccg cgtagaataa tgaaacatcc cacggctcca gctacaatcc
    10201 cgacgacaat agctgttatc aaggcatttt gtaggaaatg gaatttttgc aatccatcga
    10261 taaattctgc aatcataggt cacctccatt gaaaaagagt tgattaccgt aagcttcttt
    10321 tagattggtt tcggtaaaag tttcttttgt tggaccaaag gcaatcactt ctcgattgac
    10381 aagtaagact tgatcgaagt agtggggaat cttgctgagg tcgtggtgaa cgatgagaac
    10441 cgtcttccca gcttttttca aatctctcag cgtattcatg atgatttcct cactgacaga
    10501 gtcaatccca gcaaagggtt catccaagag gatatagtcg gcttcctgca ccaaacatct
    10561 ggcaatcaag acccgctgga attgacctcc agacagttga ctaatttgac gttcagcgta
    10621 gtcagctagg ccgacgattt caagggcctc ttgcactttc ttccaatgtt tagcctttaa
    10681 acttcgaaag agaggaatag agggaaatag tcctaacgag acgcattcct tgaccttgat
    10741 gggaaagttg tagtcgatat tgattttttg ttcgacatag gcaattcggt gtaaggattt
    10801 tttaacttcc ttgtcatcga gaaatgcctg accttgatgt gggataattc ccaacatacc
    10861 ttttaatagt gttgatttcc cagcgccgtt tggaccaatg atgccggtaa ttgttggtcc
    10921 atggagcact agtgaaatat ccttaagtgc caacgtttct ttgtaggaga cactgaggtt
    10981 ttcgatacgt atcataaact tgtattcctc ctgtctctta atatacatta aaaaaaaaat
    11041 taagtcaagt taatttttga aaaaattaaa ataataactg aaaaatagat tctaaaaata
    11101 actttcagga taaatttcta aattataaaa cgcatagtat caagtgtaaa aaacttggaa
    11161 ttatgcgttt tatcatggaa aggtttttta taatagctaa aaaataatag ttaaatggtt
    11221 attaattgca ttccctagtg atttttgtta agataaaggc aaatacaaat gaaagcgaga
    11281 acaagatgac acgttatcaa gatgattttt atgatgctat caatggagaa tggcaacaga
    11341 cagctgaaat cccagcagat aagtctcaaa caggaggttt tgttgattta gaccaggaaa
    11401 ttgaagacct gatgctggcg acaacagaca agtggttagc aggtgaagaa gtgcctgagg
    11461 atgctatctt ggaaaacttt gtcaaatacc accgcctagt tcgtgatttt gacaagagag
    11521 aagctgacgg tatcacacct gtcttaccac tccttaaaga attccaagaa ttggaaactt
    11581 ttgcggattt tacagctaaa ctagcagagt ttgagcttgc aggaaaacca aacttccttc
    11641 cttttggtgt atcgccagac tttatggatg ctagaatcaa tgttctatgg gctagcgctc
    11701 caagcacaat cttgccagat acgacctact atgcagaaga acatcctcag cgcgaagagc
    11761 tcttgactct ttggaaagaa agtagcgcaa atctcctcaa ggcttatgat ttctctgatg
    11821 aagaaattga agacttgcta gaaaaaagac ttgaattgga ccgccgagtt gcggcagtgg
    11881 tgctctctaa tgaagaacgt tcagaatatg ctaaactcta tcatccatat tcttacgaag
    11941 atttcaagaa attcgcgcct gccctacctt tggatgactt cttcaaagca gttattgggc
    12001 aattaccaga caaggttatt gtagacgagg aacgtttctg gcaagcagca gagcaatttt
    12061 acagtgagga agcctggtct ctccttaaag caaccttgat tttgagtgtt gtcaatcttt
    12121 caaccagcta tttaacagag gatatccgtg ttttgtctgg tgcctacagc cgtgcccttt
    12181 ctggagttcc agaggcaaaa gataaggtca aagcagctta tcatctagca caggaacctt
    12241 tcaagcaagc cctggggctt tggtacgccc gtgagaagtt ctctccagaa gccaaggcgg
    12301 atgtggagaa aaaagtggca accatgattg atgtctataa ggagcgtctg cttaagaatg
    12361 actggctcac tccagaaacc tgtaaacagg ctatcgtgaa gctcaatgtg atcaaacctt
    12421 atattggcta tccagaagaa ttgcctgcac gttacaagga taaggtagtg aatgaaactg
    12481 ccagtctttt tgagaatgct ctagcctttg cgcgtgtgga aatcaagcac agttggagta
    12541 agtggaacca gcctgtagac tataaggaat ggggcatgcc tgctcatatg gtcaatgcct
    12601 actacaatcc tcagaagaac ctgattgtct ttccagcggc cattttacag gcgcctttct
    12661 atgacttgca tcagtcatct tctgctaact acggtggtat tggggcagtg attgcccatg
    12721 aaatttccca cgcctttgat actaacgggg cttcctttga cgaaaatggt agcctcaagg
    12781 attggtggac agagagcgac tatgctgcct tcaaggagaa aacacaaaaa gtcattgacc
    12841 aatttgatgg acaggattct tatggagcaa ccattaacgg taaattgact gtatcagaaa
    12901 acgtggctga cttgggagga atcgcagcag ctcttgaagc agctaagaga gaagcagact
    12961 tctcagcaga agagttcttc tacaacttcg gtcgcatctg gcgcatgaaa ggtcgaccag
    13021 aatttatgaa acttttggct agcgtcgatg tgcacgcacc agccaaactc cgtgtcaatg
    13081 tgcaagtacc aaacttcgac gatttcttta caacctatga tgtcaaagaa ggagacggaa
    13141 tgtggcgttc accagaggag cgcgtgatta tttggtaatg caaaaaatct agtcatcaga
    13201 aaaaaggcat ccaatcacgt gtgaaaacct tgataggatg ccttttataa tagaaagatt
    13261 tgctggatag tttacttaaa tttcgattgt catcatcttg ctaaaaaaag ggattgaagg
    13321 ctttttcgtg agcgatagta gtagctggac catgtcctgg atagacatcg tagtttggta
    13381 gggtgaagag ttgggtctgg atactatgaa ggagttgctc catgctacca gtcggaaggt
    13441 cggtccgtcc gatagtttcg cggaatagag catctcccgt caagactagg taagcatcag
    13501 gaaagactag ggaaacacca ccgatagagt gccctggggt cggtagaacc ttaaaacgaa
    13561 attcctctag ttggtattct tcgtgaaaga caaaggtgtg ttctgcaggt tttgtgacca
    13621 catctgccat atcatcgtgg cgagggagac cggagagatt atcgacagga gtgtagagcc
    13681 agctggcttc gctctctgcg atatagacag gaggattgcc aaacgtctcg cgaaccaagt
    13741 ccagactcat gatatggtca taatgggcgt gggtcaagag aatagcacag atcggtttgt
    13801 tgatcttctc gattgtctga cgaatggctt cccaatgact accaggatcg acgacgatga
    13861 ggtgcttttc gccttctaga taataggtat tttcataggc aacaggattc acggttttat
    13921 ggattttcat actagctcca atctcaaaga atgtactaat actcttcgaa aatctcttca
    13981 aaccgcgtca actttatctg caacctcaaa gcagtgcttt gaacagcctg cggctagctt
    14041 tctagtttgc tctttgattt tcattgagta taaattaagt atagcacagt tagggagaat
    14101 aggtaaggat ttaaaatgaa cttaaaaatc agcatgacta gatgaagaca ggctggttat
    14161 caatttatca atattggaaa ggtgtcaatt gcccttcata ggttgcataa actccgtcat
    14221 tagcttgttt gatagacgtg atgtttagag tgctaccgta gttggcttct catttgtcgc
    14281 tatattcact ataagttatc ctactgggca ggttctggtc gttagcatag tattgaacga
    14341 gttttttata gctttgctgg ctgaatagga acaggcagca aactcctaac attaggagag
    14401 caaagataga aatagcagtt tttttcatag gtattctcct tataaactaa aggatagaag
    14461 aaagtatctt gaggattttt atactcttca aaaatctctt caaaccgcgt caactttatc
    14521 tgcaacttca aagcggtgct ttgagtaacc tgcggctagt ttcctagttt gctctttgat
    14581 tttcatttag tattaattcc aaaatccagt caaggtacca gtgtatgtgc tacgagttcc
    14641 accgtttatc tttcgtattt tcaatggaat tggggaagtc agaaagtctt tgggttacaa
    14701 tatggtttcc gttcttctat ctctccttct atcacctaag tttaaaatct aacttcgtag
    14761 tatattatgg gctaataatt cagaattatc aagcaatttt gaattatttt tttcttattc
    14821 tgttccaatc tagttttcat attcttaaaa aagtgataaa atggtaggaa gaattggaga
    14881 gtagagatgc cgaaagaagt gaatttaaca ggcgaagaag ttgtcgcttt aaccaaagaa
    14941 tatttaacgg aagaggatgt tcattttgtc cataaggcct tggtctatgc tgttgaatgc
    15001 cacagtggtc aatatcgcaa atcaggcgag ccttatatca ttcaccctat ccaagtggca
    15061 ggtattttag ctaagctaaa gctggatgct gtaacagtag cttgtggatt cttgcatgat
    15121 gtggtggaag atacagatgc gactttggac gatttggaaa gagagtttgg tcctgatgtg
    15181 cggatgattg ttgacggagt taccaagctt ggcaaggtcg agtacaaatc gatcgaggag
    15241 caattagcgg aaaatcatcg caagatgctc atggccatgt ctgaggacat ccgcgttatt
    15301 ttggtcaaac tgtctgaccg cttgcacaat atgcggaccc tgaaacatct tcgaaaagac
    15361 aagcaggagc gtatttccaa agaaaccatg gaaatctatg ccccacttgc ccatcgtttg
    15421 gggatttcca gtgtcaaatg ggaattagaa gacttgtctt tccgttatct caatccaacg
    15481 gagttttaca agattaccca tatgatgaag gaaaagcgca gggagcgtga ggccttggtg
    15541 gatgaggtag tcacaaaatt agaggagtat acgacagaac gtcacttgaa agggaagatt
    15601 tatggtcgtc ccaagcatat ttactcaatt ttccgcaaaa tgcaggacaa gagaaaacgg
    15661 tttgaggaaa tctatgatct gattgctatt cgttgtattt tagataccca aagtgatgtt
    15721 tatgccatgc ttggttacgt gcatgaattt tggaaaccga tgccaggtcg cttcaaagac
    15781 tatattgcca accgcaaggc caatggttat cagtctatcc atacgactgt ttatggacca
    15841 aaagggccga ttgaattcca gattcgaacc aaggaaatgc acgaggtggc tgagtacggg
    15901 gttgcggctc actgggctta taagaaaggt ataaaggggc aagttaacag caaggaatca
    15961 gctattggaa tgaactggat caaggagatg atggagctcc aagaccaggc tgatgatgct
    16021 aaggaatttg tggactctgt taaggaaaac tatttggctg aggagattta cgtttttacc
    16081 ccagatggag ctgtccgttc ccttcccaaa gattcaggac cgattgattt tgcctacgaa
    16141 atccatacca aggtcggtga aaaagcaact ggtgccaagg tcaatggccg catggttcca
    16201 ctgacaacca agttaaagac aggggatcag gttgaaatta tcgccaaccc gaactccttt
    16261 ggacctagcc gtgactggct caatatggtc aagactagca aggcgcgcaa taagattcgc
    16321 cagttcttta aaaaccaaga taaggaattg tctgtcaaca agggtcgtga gatgctgatg
    16381 gctcagttcc aagaaaatgg ctatgtggca aataaattta tggacaagcg ccacatggat
    16441 caagttctgc aaaagaccag ttacaagaca gaagactccc tctttgcggc cattggtttt
    16501 ggggaaatcg gtgcgattac cgtctttaac cgtctgactg aaaaggaacg ccgtgaggaa
    16561 gagcgtgcca aggccaaggc tgaggcagag gagcttgtca aaggtggcga ggtcaaggtt
    16621 gaaaataaag aaactctcaa ggtcaagcat gaggggggag tggttattga aggtgcttct
    16681 ggtctcctag tgcggattgc taagtgttgt aaccccgtgc ctggtgacga tattgttggc
    16741 tacattacca agggtcgtgg tgtggctatt caccgtgtgg actgtatgaa cctgcgtgcc
    16801 caagaaaact acgagcaacg tctccttgat gtggaatggg aagaccagta ctctagctca
    16861 aataaggagt atatggccca tatcgatatc tacggtctca accgtacagg actgttgaac
    16921 gatgtactgc aagttctttc aaatacaacc aagaatattt caacggtcaa tgcccaacca
    16981 accaaggata tgaagtttgc taatatccat gtgtccttcg gtattgccaa cctctctaca
    17041 ctgaccacgg ttgtcgataa aattaagagt gtgccagaag tttactctgt caaacggacc
    17101 aacggctagt tgtcctagct cttactagaa aggctattat gaaaatcatt atccaacggg
    17161 ttaaaaaagc ccaagtgagt atagaaggcc agattcaggg aaaaatcaat cagggacttt
    17221 tattgctggt tggtgttgga ccagaggacc aagaggaaga tttggactat gctgtgagaa
    17281 aactggtcaa tatgcggatt ttttcagacg cagaaggcaa gatgaacctg tctgtcaaag
    17341 atattgaagg agaaatcctc tctatttctc agtttaccct ctttgcggat actaagaaag
    17401 gcaatcgtcc agcctttaca ggggcagcta aacctgatat ggcatcagac ttctatgatg
    17461 ctttcaatca aaaattagcg caagaagtgc ccgttcagac aggtatcttt ggagcagata
    17521 tgcaggttga gctggttaat aacggacctg ttaccattat cctagatact aaaaagagat
    17581 aagaaagacc aagcccagtc ggcttggtct ttctcatcga tcataaaata ctccaaaaag
    17641 aaatcggttc ttgatatgct tgggggaagt ctcttttcag gctttggcag atgcgatagg
    17701 aagggatgag atgtcctagg atgaggagag ttccctgaag gaaaagtgga atatcactta
    17761 aagacaccaa ggagagaatc atcaggctat cccataggag aatttgtaaa gcaaaacgtc
    17821 agaatctcgg tctaatctgg gaatagagtt gactaaagtg gtcacaaagt tggtttgaaa
    17881 gataggtcaa tagcacagga tgaaagaaaa tgagccaacc actataaatc aaaatccagt
    17941 cccaagtaag cccccctttt aaatgtcaaa aatgccagca tgattccatc aatgacaagg
    18001 agttgaatgg ttttgatgaa gatgattttt ttcatgctaa aacctccttt tttcatctgt
    18061 tagtgacgta atgctttata taattattat acagtattca gtcgggatat gaaaacgttt
    18121 actatcgttt ttgatataaa aaatagataa gaaaaccctg aaaataaaac tttcagggtt
    18181 ggtaggggac ttgagaaatt agttgatttt ctcgacatag agttgttttg caatgtccat
    18241 attcacttgt aaatcctcgt cgttactgag gatagtgaag gtattgctga agccatcaaa
    18301 ctgcttgact tggagctggt caccgatgtg aagtgagtgc ttgtccagat aatggagaat
    18361 gtcaaaacta tcgtgcaccc gagtcaggcg gtaggcgcca gcttccttga tatcagctag
    18421 tgggaggtta ttgatttcaa cgaggagttc tcccttggca ggaatagttc ctccgtgggg
    18481 gcaggtttta gggaaaccta gcagtttatc tagtctttcc acgaacaggt cagagacagt
    18541 gtgttccaag acctcagctt cctcgtgaat ctggtcactt gtatagtcta aatgatgaac
    18601 tagaaaaact tcaatcaagc ggtgcttacg atagagctca gagaccagtt tgagaccgag
    18661 gtcagtcagt agatagccac attccttgtc ctttaggatg agattttcac ttttcattcg
    18721 tttgatcatt tcagttacgg cagggggaga gacttgcatg cgagccgcaa tttccttgtt
    18781 ggtaatctta tgcaggtcta tgccaatttc ataaatacat tttagatagt cttctttgtt
    18841 tggggtcatt cgtttcctct tgtctaatat ctttatctag tatatcaaaa aaagctagat
    18901 ttctctagct gtgacttttt atgttatact tattgcaaga gaaaaaacga ggagatggat
    18961 atgacgaaaa tagctcttct ttcagatatt catggaaata ccaccgcctt ggaggctgtt
    19021 ttggcagatg ctcagcagat aggagtggat gaatactggc ttttgggaga tattctcatg
    19081 ccagggacag gacgtagaag gattttggac ttgttggatc aactaccgat tacggctaga
    19141 gttttgggaa actgggaaga cagtctttgg catggtgtcc gtaaggaatt ggacagtact
    19201 cgccccagtc aacgctatct cttgcgccag tgccagtatg ttttagagga aatttcccta
    19261 gaagaaattg aagtgctcca caatcaacct cttcaaattc atcgtcagtt tggggatttg
    19321 acggtgggaa ttagccatca tctgcctgat aagaactggg ggcgagagtt gattcatact
    19381 ggcaaacaag aggagtttga ccgcttggtg actcatcctc cctgtgatat tgctgtttat
    19441 ggacatattc accagcagtt gcttcgttac gggactggtg ggcaattgat tgtcaatccg
    19501 ggttcgattg gccaaccttt ctttttggac gctcagctac ggaaggactt gcgggcctag
    19561 tatatgattt tggagtttga tgacaagggt ctggtagata tggacttccg acgggtagac
    19621 tacgatgtgg cagcggaatt gcagctggct aaagacctga gacttcccta ttttgaggtt
    19681 tactatgaaa gtctggtcaa tgggatccac catactcatc atcaggaatt tttgagagaa
    19741 ttggctcaga aagagggctg cgatcgggag ttagacgact ggttgaaaag tggtaacgat
    19801 tgacattaca actaaaaagg gtataataat agaaaaagaa gagtagaggc agggtagcct
    19861 cgtaaaaagg agaagaggat gcaaattcca agtagattta ccattgcgac tcatatgctg
    19921 ataatcattg ccctcgaggg gaaggaaagc aaggtgacca gtgattttct ggctgctagt
    19981 gtcggggtca atcctgtcat tatcagaaat atcttgtccc agttgaagaa ggcagagctg
    20041 atttcagtag cgcgtggaac gggcggaaca gagattgtca aggaccttaa ggatattagt
    20101 cttttagatg tttatcaggc ggtcgaatgt cttggtaaga caggtcaact cttcagtttc
    20161 catgacaatc cgaatccaaa ttgccctgta ggagctcata ttcatgatgt tttggatcaa
    20221 aaattggaga gaattcagtt gactatggag gcagaacttg gtcaaaccag tctagaaaaa
    20281 gtcgtggccg atgcagagag tcagatgaag gattaagagg gataaatgcc ctcttttttc
    20341 tttggataat tatgataaaa tgtagctatt aaaggagtaa gaaatgtatc tcgttatagg
    20401 aattgtatta gcctttatag tgtcattttg gaaggataat agaagtttgt ggaatccagt
    20461 attattttta ttatccctca tttcaagtta tttttatcta tcctaccttt tttataaaaa
    20521 tggatacgag aatgttcagt tagcttttta tgtatttacc tttgtcttac ttcctttttt
    20581 gctttttcta agtggcatct ttttaatcta taatggggtc attttgttga agtgagaggg
    20641 acgttccaag ccccattatc tctcaatgct ctttgatttt tattgactat tagattctat
    20701 ttaaaaagac ttagaatgca catgaaagta tgtattctag gtcttttgtt ttgtatacat
    20761 ttaattttca agagtattat ctatttttcc atgcctggta acgagtatca atcaataact
    20821 gggtaaggcg acccaaggtt tctctttctt ctggagtgag ggattgagct tggacaaaga
    20881 gatgatgaat gtattcaagc gcctttaagg aagccaagtc gttgatagag ctaataccag
    20941 catcaagaat agtgccaaag aagaggtcga agtagagctg aagttcttcg tcagggactg
    21001 tggccaccca ttctttaaag gttgtgtcta cttgctggct atcactgttg gtcttatcca
    21061 gttggacgaa gtgcttgtcc tcaatctgcc aactaaaggt atcgtgctgg gcgatgccac
    21121 ccagggcagt actctgaacg atgatttggt gagcaggaat ttccagcatc ataccgataa
    21181 tggaaccttg tggaatgaat atcttgcttc tatccattat cctttgataa cccgcagtct
    21241 gtgtcaattc ttgatggaga ccaggtgcat caaatgtata aactgctgtg atctgatttt
    21301 gcaaactttg ctcaatttgg ctagcagcat agatagcgag atttcctccc ttggaatgcc
    21361 cagccagaat aaccttttgc ttaggatgat gggcaaaaaa gttctttaaa tagcgaaggg
    21421 cgtgcttttg agcaggaatt tccttcatat aggtcaggtg gaaatcttcc ttccagccaa
    21481 tgatactgtc atctgtccca cgaaagacaa tcagataggt atcgaggctg acacgataag
    21541 tcatagccgc aaattgcttt tgcagttcag ggtcgatgtc gttgataaaa tgggagagtt
    21601 tgcaattttt gaagcgcttg tgttgagcca attcatctaa taattgaagg cgatttttgc
    21661 tagtaagcat ggtgggctct cttggaacct gaggtgctag ctctaaaaga cgttgaggaa
    21721 gtgtggagac cagattatca aaggagaggt aggtgatttc tattaaggtt agaatgtcta
    21781 actcattcaa gggaaggtcg taataagaat catatgcgac atctttcaga tagtcaaaaa
    21841 tattggccat aagagctcct ttctttttat ttatcttagc aaatttccct caaattagct
    21901 agtagcattg cctgtttgta ctggctaaaa acaggctatt tcaaattcag tttcagacca
    21961 tctggcatgg aaaaatctgt tataataatg gaaaaggaga agcgcatgca caagatttta
    22021 ttagtggaag atgatcaggt cattcgtcaa caggttggga aaatgctctc tgaatgggga
    22081 tttgaagtgg tcctggtaga agactttatg gaagttttga gtctatttgt tcagtcggaa
    22141 cctcatctgg tcctcatgga tattggtttg cccttgttta atggttatca ctggtgtcag
    22201 gaaatccgca agatttccaa ggtacctatc atgtttcttt cttcgagaga ccaggctatg
    22261 gatattgtca tggcaatcaa tatgggggcg gatgactttg tgaccaagcc ttttgaccag
    22321 caggttcttt tagctaaggt tcagggcttg ttgcgtcgtt cctatgagtt tgggcgtgat
    22381 gagagtttgc tggaatatgc tggtgttatc ctcaatacca aatccatgga tttacattat
    22441 caagggcaag tcttgaattt gaccaagaac gaattccaga ttttacgcgt gttatttgag
    22501 catgcaggca acatcgtagc acgtgacgac ctgatgcgag aactttggaa cagtgacttt
    22561 ttcattgatg ataataccct ctctgtcaat gtggctcgtt tgcgtaaaaa gttggaggag
    22621 cagggattgg taggatttat cgagaccaag aaaggaatag ggtacggatt gaagcatgct
    22681 tgattggaaa caattttttc tagcctatct gcgctcccgt agtcgtcttt ttgtctatct
    22741 gctttctttg gcatttctgg tcttactctt tcagttttta tttgccagtc taggaattta
    22801 cttcctctac tttttcctct tgtgttgctt tgtaaccatc ttatttttca cttgggacat
    22861 attggtggaa atgcaggttt atcgccagga acttctctat ggagagaggg aagccaagtc
    22921 tcctttggaa atagctttag cagaaaaatt agaagcgcgt gagatggaac tctatcagca
    22981 gaggtcaaaa gcagaaagaa aactgacgga tttgctggat tactatacct tgtgggtcca
    23041 tcagataaag acccccattg cagccagtca actcttagtt gcagaagtgg tcgaccgcca
    23101 actgaagcag cagctagaac aggaaatttt caaaatcgac tcctatacca acctagtttt
    23161 acagtacctg cgtttagaaa gtttccatga tgatttgctc ttaaagcagg ttcaaattga
    23221 ggacttggtc aaggaaataa ttcgtaaata tgctcttttc tttattcaaa aaggcttaaa
    23281 tgtcaatcta catgaccttg ataaagaaat cgtgacggat aaaaagtggc tgctagtggt
    23341 tattgagcaa atcatctcaa acagtctcaa gtacaccaag gaaggtggtc tggagattta
    23401 tatggatgac caagagcttt gtatcaaaga tacgggaatc gggataaaaa acagtgatgt
    23461 cctccgagta tttgaacgtg gcttttcagg atacaatggc cgtttgaccc agcagtcctc
    23521 tggacttggc ctttatctat ctaagaaaat ttctgaagaa ctggggcacc agattcgtat
    23581 cgagtctgag gtcggaaaag gaacgacagt gcggattcag tttgctcaag tgaacttagt
    23641 ccttgagtaa aaatagatga gaaaaagcct ccagattgga ggcttttatg ctagactctt
    23701 atttctcaac gcgtgatttg ttggcgatat cagctaggat agcttgaaca aaattatcaa
    23761 ctgagacagt ttgtgtttct ttttggccgt agcgacgaac gttgactgtt tcgtcttcca
    23821 tttctttgtc tccaacaatt aattggtaag gaatcttgct ggtttgtgaa gcacggatct
    23881 tgaactgcat tttttcattg cgctcatcta catctgcacg gacaccgcgg tcacggagtt
    23941 tcttggccac ttcccaagcg tagtccacgt gtttttcgtt agatactggg atgagggtta
    24001 cttggtgtgg tgccagccat gttgggaagg cccccttgta gttctcaatc aagatagctg
    24061 tgaagcgttc catagttgag ataactccac ggtggatcat gactggacgg tgatcttcgc
    24121 catcagctcc gatgtatttg aggtcgaagc gttctggcaa caagaaatca agttggatag
    24181 tagaaagggt ttcttctttt ccaagggcag ttttaatctg gatatccaat tttggtccgt
    24241 agaaggctgc ttcaccttcg gcttcaaagt agtccacgcc catttcatca agagctgcac
    24301 gaagcatggt ttgggcattt tcccacatct catcgttatc aaagtactta tgagtatctt
    24361 gagggtcacg aagagagagg cggaagcggt agtcagtcaa gttgaagtct tcataaacat
    24421 cgataatcaa ctgaagggca cgttggaatt cttcttggat ttgttctgga gtaacgaata
    24481 ggtgaccgtc gttgagtgac atttcacgta cacgttgaag gccagtgagg gcaccagatt
    24541 tttcgtaacg gtgcatcata ccgatttcag cgatacggat tggcaattca cggtaagagt
    24601 gaacatggtg tttaaaaact tggatgtggt gcggacagtt cattggacga aggacaaatt
    24661 cttccccgtc acccatgtcc atggttggga acatgtcttc ttggtaatga tcccagtgac
    24721 cagaagtctt gtaaagctca acagaagcaa gtggtggagt gtagacgtgt tggtagccag
    24781 aagccaactc tttgtttacg atgtagcgtt ccaattcacg acggatagtc gcaccatttg
    24841 gcaaccagaa tggcaaacct tgtcccactt cttgtgaaat cataaagagg tcaagctctt
    24901 taccaagttt acggtggtca cgttccttag cttcttcacg catttgaagg tagtttttca
    24961 agtctttctt gtcaaaccaa gctgtaccgt agatacgttg catcatagcg ttgtcgctgt
    25021 ttccacgcca gtacgcacca gctacatgga gaaggtggaa gatttggata cgacctgttg
    25081 atggaacgtg aggtccacgg cagaggtcta catattcacc ctgacgatag atagtcaaac
    25141 cgccttcgtc ttctgagtgt tcttcaatca attccaactt gtaagggtca tttttgaaga
    25201 tttcacgtgc ctcgtcttta gtcacttctt cacgaataga tgggaagttt tctttgacga
    25261 ttttttgcat ttcttcttcg atacgaggaa ggtcttcgtt agagatttga ccagctgtgt
    25321 tgtcagtatc gtagtagaaa ccatcttcga tggctggacc aactcccaag tgaatgtctg
    25381 ggaaaagacg acgagctgct tgggcgaaca agtgagctgc tgagtgacgc aagattggaa
    25441 gggcatcttc gtgatcaggt gtcacaattt cgatgcttcc atcttcagtg atagcgcgag
    25501 tagtgtcgat gagtttgccg ttgaatttac cagccaaggc ttttttagct agggaattgc
    25561 tgatagattg ggcaatttca aaagttgtta cgccagattc gaattcacga acagcgccat
    25621 ctgggaaagt aatgttaatc atgatgttct ccttttttat tatttcatag tttctaagca
    25681 ttgatttttt atcagcagac tacttccgag tcctaacgtt caattgcttt tctttatcag
    25741 agaggaagtt tttcatttcc gtcagaatgt ctatatccaa acgttgagaa agttctaata
    25801 gccaccagat attttctgaa agtttttgtt ccagtgtgta gggtgtttca tcatagtagc
    25861 gtccttgctt tgtcatcacc agtcattgga aatttccaat atcattagat aaagccaaga
    25921 ggtcttcttc taccgtccac ttgaaatcat gatgcttaac ttccagttcg tgataagctt
    25981 gtcggattgc ccaactgcgc tccactaatt cttgcaactc cataattagt atcctaataa
    26041 aaaaatgcga catcctcgaa aggacgtcgc aacgtggttc caccttcatt tatgtacctc
    26101 aaaagagagg gacacctctg atcggctcta acgtggccac cgttttatgt tttcataaaa
    26161 aactcaagag tagtatcagt ttagacttcc tatgcgtttc cagcaaccac gcactctcta
    26221 gtagaaaggg actaagtgac ttgtctctat ggattattat agcatgattg tgagattttt
    26281 caaggatttt gtgaaagttt tttgtttttc attttttgta gaatatgctt gatgctaata
    26341 ccagaatcca tgccgaccag agcaactgtt tcatagatta gcaagtaaat tagtataaac
    26401 tcaccaaagg ttatgatagt aaagtaaaag agcagtccgt taccaactaa ccatcaaagt
    26461 gagaaacgga aacggtagct atagagtaac gatataatca agattaccag aggtgtaaag
    26521 aagagaagat tgtttatata gagttccttg agtgtaaggg ggtcagaaac aactagtaag
    26581 aacaactcat aaagtggcca ataaaagaat aatatgacca gatagtaggg gagatgggaa
    26641 tagaatctac gcatgataat cacctcgttt taaaaaaaca gacaacttag atctcttgct
    26701 atgattatta tagcatgttt aaaacaagaa agtaaatttg ttgacaaaga agatttttct
    26761 tttcactaga atcatagtta gttttcttgg tagaaatatt ttgataataa ttaagcaaga
    26821 ctattgacat taattattaa gagtgtcaca attgttgtaa ctaaaataat tacaacaaga
    26881 gaggtataaa aaatgaaact agcagttatt gcagcaaatg gacaagcggg gaaagcaatt
    26941 gttgaagaag cagtcaaacg aggacatgaa gtaacggcta ttgttcgttc tgaaaacaaa
    27001 agtcaagctg agtctattat taaaaaagat ttatttgagt tgacaaaaga tgatcttact
    27061 ggatttgatg ctgttatttc agcgtttggt gcttatacac cagatacgct accgctccac
    27121 agcaaatcaa tcgaactatt taatcagctt cttgctggaa cacagacacg ttttctagtt
    27181 gtagggggag caggaagtct ttatatagat gaaacaaaaa cgacacgact tttagatacg
    27241 tctgattttc ctgaagaatt taagtcacta gcaaaagctc aagcggatga attggatctt
    27301 cttcgtacaa aaaataatct caactggact tttgtcagtc ctgctgtaga ttttattccc
    27361 gatggtgaaa aaacaggaaa ctacattcta gcaggagaaa tttttactac taatgaaaaa
    27421 ggaataagcc agattagtta tgcagattat gctattggat tggtagatga acttgaaaaa
    27481 ggtcatcata taaaagaacg tatctcttta cttgaaaaat aataactatg agagtattaa
    27541 tgtttgacag aaaatttaaa tcttggtaaa atagggattg tcgtaaagac aaataacttc
    27601 ttcttggtta caggcatgcc aacctgtcac tcggatgaag ccaaataaaa aggagaaaca
    27661 tcatggcaat ctcaaaagag aaaaaaaatg aaatcattgc acaatatgca cgtcacgaag
    27721 gtgatacagg ttcagtagag gttcaagttg ctgtccttac ttgggaaatc aaccacctta
    27781 acgaacacat caaacaacac aaaaaagacc acgctactta ccgtggattg atgaaaaaaa
    27841 tcggtcgccg tcgtaacttg cttgcatact tgcgtaaaaa cgacgttaac cgttaccgtg
    27901 agttgatcaa ctctctagga cttcgtcgct aattcaagat acaaatgctg tcaaaagcac
    27961 aaagcaaaaa taggaaaatt gacgaagaaa cttcagtttc taggagattt tatctttttt
    28021 gccaagtgct taggccgtgt tcaattgagc atatcttgat aatgaagcta ctctaaattg
    28081 ggtagctttt ttgcgttgtc accttacctc gatatactca agtataatct ttggttacgg
    28141 ttcctagcac tgtaaggtaa aataaaccag cttttctccc ttcggggaga tttttttgtt
    28201 tcactgaaag tttcgtacga tcttcgcctc gtcgcctagt ctataaacga tttatctagc
    28261 agaatcatga tgctaagggc gtcaaaaatc cgtatgaaaa tagggaaatg acacagtgtt
    28321 cgatgagcac aaggagtttc atctttttca ctaggatttt agcccgggct caaatcagct
    28381 ctctgacttc agagggcttt tttattgagg ttttatcggt aacaattttg gagactacaa
    28441 aaacctcaaa cggtatcagc taattacacc ataaaggtgc gcagttactc ggcttttcaa
    28501 gccgagtaac tgtatgcaag ccccctagaa gagcccactc tttacaaagt aaagtatagt
    28561 atgttatact ttacatggaa gtagtcactg aattccagtt agaaattact ttgtaactac
    28621 gttttgagga ggagtaaaat gctttcctac gttcgacatt acccactagc gatagctaaa
    28681 ttaatgtgtc tgtgctctcc taaaatctgc tgatttatta ctgactaata caggaggttt
    28741 tttttatggg acagacaatc atatctgcta ttggtgttta tatttccacc agtatcgatt
    28801 atttaattat tttaattatt ttatttgcac agctatcaca gaataaacag aaatggcata
    28861 tttatgcggg gcaatatcta ggcacaggct tacttgtagg ggcgagttta gttgctgctt
    28921 atgtcgttaa tttcgtgcct gaagaatgga tggttggatt gcttggttta atccctatct
    28981 atttagggat tcgctttgca attgttggag aagatgcgga agaagaagag gaagaaatta
    29041 ttgaaagatt agaacaaagc aaggcaaatc aactgttttg gacagttaca ttgctgacaa
    29101 ttgcgtctgg cggagataat ttaggtatct atatacctta ttttgcttcg ttagattggt
    29161 cacagaccct cgtggccttg cttgtgtttg taatcggcat aattatcttt tgcgagatta
    29221 gtagggtgtt atcctctatt ccgttaatat tcgagacaat tgaaaaatac gagcgaatca
    29281 ttgtgccctt agtattcatt ctacttggac tatacatcat gtatgaaaat ggcacgatag
    29341 agacttttct gatcgtgtag atttttttgt ttcactagga ttttagcccg agctcaaatc
    29401 agctctctga ttttcagagg gctttttcat tgagtataaa tggacaatct taaagttact
    29461 ctattgtaga gtggcttttg atttgattag gagattctta taaatatagt aaaatgaaat
    29521 aagaatagga caaatcgatc aggacagtca aatcgatttc taaaaatgtt ttaagaagta
    29581 gaggtgtact attctagttt caatttgata tataaatgaa aaccttagct gtttggccaa
    29641 ggttcatttc ttctatgcaa gttcttctct tttcttatct gggttccaga tgaagcttgc
    29701 gataaagcta aagatgatgg ttaggatagc gaggataata gcaaggatga gggcagggat
    29761 gcggataaac caccagagtg gatttggttt tttatcattg tgccattgtt tcgtttcttc
    29821 gtccagacgt tggaattctg tttgaatacg attggcgact gtttcaatgc cttcatcatt
    29881 cattttcttg atatctgaga tatcgattgg atttccaaag ttcatatcga cacgttcacg
    29941 gctaatcaag cccttcaaag tcatgggacc ggtgtaggta accggcatga tacggacctt
    30001 ggccattttg gcaatcagtg ctgcgccccc cttgacatcg tttgagtggc ggctaccact
    30061 tggaaacatg atgagagagc ggtcactttt tttgagaacg ttgataggat atttgatggc
    30121 tgaggcgctg ggattttcac ggtcgatggg aaaggcgcca cacatacgaa tccaccaacc
    30181 aaagatacgg ttggtaaaga gttctttttt tgccataaag atgaactgtt ttggcttggt
    30241 cgcaaaggcc atataaacag gatcccacca ggtacggtga ggcgcaacta aaatataatt
    30301 ttcatcttga ttaggaattt tatcagtatt atgatagtga gcattgccat tgatggacca
    30361 taagagcaat acaactaatc cacgcaaata agtataaaac atgcgatctc cttcgattgt
    30421 tttcttgtta ttattatacc ttatcaaagg agggctggca aacttttccc ttgactagat
    30481 acatatttag gatgaaatta gaattctgtt aaaaaaaatg atataataga atttatggat
    30541 aaaaataaga ttatgggatt aacccaaaga gaagtcaagg aaagacaggc tgagggtttg
    30601 gtcaatgact ttaccgcatc agccagtacc agcacttggc aaatcgttaa acgaaatgtc
    30661 tttacccttt ttaacgcttt gaacttagcc attgctttgg ctcttgcctt tgtgcaggct
    30721 tggagcaatc tggtcttctt tgctgttatc tgctttaacg ctttttctgg gattgtgacc
    30781 gagctacgag ccaaacacat ggtggacaag ctcaatctca tgaccaagga aaaggtcaaa
    30841 accatccgtg atggtcagga agttgctctt aatcctgaag aattagtgct aggagatgtc
    30901 attcgtttgt ctgcaggaga gcagattcct agtgatgcct tggttttgga aggctttgcg
    30961 gaagtcaatg aagccatgtt aacgggagaa agtgatttgg tgcaaaagga agttgacggc
    31021 ttacttttgt caggaagttt cctagccagt gggtcagttt tatctcaagt tcaccatgtc
    31081 ggtgcagaca actatgctgc caaactcatg cttgaggcta agaccgttaa acccatcaac
    31141 tcccgtatca tgaaatcgct ggacaagttg gctggtttta ctgggaagat tatcattccc
    31201 tttggtctgg ctctcttgct ggaagccttg cttttaaaag gcctgcctct caagtcatct
    31261 gttgtaaact cgtcgacagc tcttttggga atgttgccta agggaattgc ccttttgacc
    31321 attacttcgc tcttgactgc agttatcaag ctaggtttga aaaaggtctt ggtgcaggag
    31381 atgtactctg ttgagacctt ggcgcgcgtg gatatgctct gtctggacaa gacgggtacc
    31441 atcacccaag gaaagatgca ggtggaggct gttcttccgt tgacggaaac gtatggtgaa
    31501 gaggctattg ccagcatctt gactagctac atggcccata gtgaggataa gaatccaact
    31561 gcccaagcca ttcgccagcg ttttgtggga gatgttgctt atcctatgat ttccaatctt
    31621 cccttctcca gcgaccgcaa gtggggggct atggagttag aaggcttggg gacagttttc
    31681 ttaggggcac ctgagatgtt gctggattct gaagtcccag aagccaggga ggccttggag
    31741 agaggatcac gtgtcttggt cttagctctc agtcaggaga aattagacca tcacaaacca
    31801 cagaaaccat ctgatattca ggctctagcc ttgctggaaa tcttggatcc tattcgagag
    31861 ggagcggcag agacgctgaa ctatctccgt tctcaggaag tggggctcaa gattatctct
    31921 ggtgacaatc cagttacggt atccagcatt gcccagaagg ctggttttgc ggactatcac
    31981 agctatgtcg attgttcaaa aatcacggat gaggaattga ttgctctggc ggaggagaca
    32041 gcgattttcg gacgtgtttc ccctcatcaa aagaaactca ttatccaaac gctgaaaaaa
    32101 gcgggtcata caacagctat gactggggat ggagttaatg atatcctggc tcttcgtgag
    32161 gcggattgtt ctatcgtaat ggcggaggga gacccggcaa cccgtcagat tgccaacctg
    32221 gttctcttga actcagactt taatgatgtt cctgagattc tttttgaagg tcgtcgtgtg
    32281 gtcaataaca ttgcccacat cgctccgatt ttcttgataa agaccatcta ctcattcttg
    32341 ctcgcagtta tctgtatcgc cagtgcttta ctaggtcggt ctgaatggat cttgattttc
    32401 cccttcattc caatccagat taccatgatt gaccagtttg tggaaggttt cccaccattc
    32461 gttttgactt ttgagcgaaa tatcaaacct gtcgagccaa acttcctcag aagatccatg
    32521 cttcgtgccc taccaagtgc cctcatggtc gtgtttagcg ttctttttgt gaaaatcttt
    32581 ggaacgagtc aaggttggtc tgagttagaa atctcaactc tcctctatta tctcttgggg
    32641 tcaattggtt tcttatccgt atttagagcc tgcatgccat tcactctatg gcgagtccta
    32701 ttgattgtct ggtcagtagg aggcttccta gccacagctc tcttcccaag aattcaaaaa
    32761 ctgcttgaaa ttgcaacctt aacaggacaa acattacctg tttatggtgt catgatgttg
    32821 gtctttaccg tgattttcat cctgaccagt cgttaccaag agaaaaaata aagaaagact
    32881 gcaatctgtg gattgcagtt ttttatacga tggatctatc gtagatctga tgtgcaaggc
    32941 ctacgtgccg atcatctatc ggtgaaccca agagcgaccc tcaagcctgc ttggattgag
    33001 gtaatagatt caaatatctg tagttagact atttgaagtt tgatgtaaga aagagaaagc
    33061 gacagattga agtaatttta actctcttct attgctagaa caaatggtcg gataggttgg
    33121 tagtttgaaa atgaagatgc tatctattgt taaatggaac atagtgttat ttattagaaa
    33181 atcgtttggt ttatttctta tcaaatacga aaagcaactt aaatatttca actaaaatag
    33241 atgttatgaa gaaaaggtaa aatgattttg gcatagtgag gttctgttct atttgatatc
    33301 atatttttga taaaaacaaa aatgtccatt gcaaaggaca aaatgcgaag tatattattt
    33361 tttgaaagcg atataatgga ttcataaagg aggtgtatcg tgtctagaaa acaagaacaa
    33421 atggaaacgt tgttgctcct tttgcgagat agtaaggatt atatatctgc taaagtattg
    33481 ggagaaaaat taaattgctc tgataaaacg gtttatcgcc ttgtcaaggg aatcaacaaa
    33541 gattgtccgg tagaagcatt cattttatct gaaaaaggca gaggtttcaa attaaatcca
    33601 agaagttccc tcgtggacgt tgatgggaat tttacagagg cttttgatcc tgaagtaagg
    33661 cgtgaaaaat tactagaacg tctcttgttg actgctccta agccacattc tatttatgat
    33721 ttaggagagg aattctacgt aagcgagtca gtagtactaa aagatcgtca gatattacaa
    33781 gagagtctag caatttatgg gttagattta aaaatgagac aacgaaagct ttttattgat
    33841 ggggatgagg ctcaaattcg ttcagccatt ctaaatctac tgccaatgtt taatcagttg
    33901 gatttagagc aaattacaca gaataaggtt cagcctcttg acggagaact tgctcacttt
    33961 tgtttgggat tactgattac acttgagaga gaattggggg taaacattcc ctatccatat
    34021 aatataaata ttttctctca cctgtatatt tttatcagta ggaatcgtcg tagtactagt
    34081 attcatgttg tagcaccttc aaaacctact attgttgatg agaaaattta cagtgtctgt
    34141 caaaaaatta ttcaagaaat tgaacaatat tttaggatga aggttgatgc agttgagatt
    34201 gactatcttt atcaatacgt tgtatcttcg agattgcaaa aaccattttc ttccgggaag
    34261 cttccttttt ctcagcgagt tttagatgtc actcattact attttagccg tatgtgtatg
    34321 gacaatagag agattgaaac gacagatcct gactttgttg acttggcgag tcatatcagt
    34381 cccttactga ggagattaga taatagagta cagattaaga atagtctttt atcacaaatt
    34441 cttttaacct atcctaatct ggttaaagag ttaacaacta tttctaaaga agtgagtcta
    34501 gtatttggtt ttgcttcctt gagtctggac gagattggtt ttctagtctt atattttgca
    34561 cggtttcaag aaaagcgagc acgtcctcta aaaacagtag tgatgtgtac atcaggtgtc
    34621 ggaacttcag agcttttacg agcacgatta gaaaagcaat tttctgaatt ggatattatt
    34681 gatgtagttg cttatcatca attagatgag ctgataaatc tatatccaga tttagatttc
    34741 attgtgacga cggtagcttt gcaggaacca gcaagtgtcc cgtttgtcct agttagtgtt
    34801 tttctaaccg agggtgataa acaacgtctt caagcaaaaa ttcaggagat aaactatgaa
    34861 taatctttcg cttgtcctta tggatatatc tgttcaaaat cgtcaagaag cctacaaaga
    34921 attagcaaat caaatcagcc ttcttgtttc tgaagataca gaaaaaatag aagagcttct
    34981 atattaccgt gagagacagg gaagtataga ggttgctaaa ggtgttcttc taccacattg
    35041 tgaaggaaac tttcaacatc atgtcttagt gattactaga ttaaaaccac ctatcagaga
    35101 atggtcgaag gatatccagt gtgttgacct tattattggt ttggccattg cagtatcaca
    35161 ggacaagtca tgtattaaaa cattgatgag aagactagca gatgaatcat tcataaatca
    35221 attaaaacag ttaacaaaag aagaattacg ggagataata tatggaaatc aaagatattc
    35281 ttaatgtgag tctgatccag acggatttac agatgcagag caaagaagag gtttttgagg
    35341 cattagctca actattggtt gagacgggtt atgtgtctga tagagaccaa tttatcgaag
    35401 gtctttatca gagagaggca gaaggacaga ctggtattgg gaattatatt gctattcccc
    35461 atagcaagag ttctgctgtg gagaaggcgg gggtagtcat agctataaat cacaatgaga
    35521 ttccttggga gaccattgat gggaaagggg tcaaagtaat tgtactcttt gcagttggtg
    35581 atgatacaga agctgctagg gagcatttga agaccttatc actctttgct cgaaaacttg
    35641 gtaatgacga agttgttgcc aaattagttc gggctcagac atctgatgat gtgattgcag
    35701 ctttttgtta ataagaaaaa attttggagg gtatccgtat gaaaattgtt ggtgttgcag
    35761 cttgtactgt gggaattgcc cacacttata ttgcacagga aaaattagag aatgccgcaa
    35821 aggtagctgg acatgtgatt catgttgaga ctcaggggac aataggggta gaaaatgaat
    35881 tgagtcaaga gcagattgat gcagcggatg tagttatttt agcagttgat gttaagattt
    35941 ctggtatgga acgctttgag ggtaaaaaga ttatcaaggt tccaacagaa gtggcagtca
    36001 aatctcccaa taaactgatt gctaaagctg ttgagattgt tacgaaataa ctgaaaatat
    36061 ttaaggagaa aatatatgtt gaaacactta aacttaaaag gtcacttatt gacagccatt
    36121 tcctatatga ttccaattgt ttgtggtgca ggattcttag ttgccattgg tttagcaatg
    36181 gggggtggtg ttcctgacgc tcttgtagca ggaaaattca ctatctggga tgctttagca
    36241 actatgggtg gtaaagccct tggtctcttg ccagttgtta ttgctacagg tttgtcttac
    36301 tcgattgctg gtaagccagg gattgcacca ggttttgttg ttggtctaat tgccaattct
    36361 gttggttcag ggtttatcgg tggtatcttg ggaggttata tagctggttt cttggttcaa
    36421 gcgattatta aaaaggtcaa agtaccaaac tggattaaag gtttaatgcc aaccttgatt
    36481 attccttttg tagcctcttt ggtaagtagt ttgattatga tttatattat tggagcgcct
    36541 atcgcagcct ttaccaactg gttgacgagc ttattacaaa gcttgggaag tgcttcaaat
    36601 ggtttgatgg gggcagttat tggagttctc agtgctgttg acttcggtgg cccacttaat
    36661 aaaacagtct atgcgtttgt gttgacttta caggctgaag gtgtgaaaga accattgact
    36721 gctttgcaat tggtgaatac tgctacacca gttggatttg gattggccta ttttatcgcg
    36781 aaattactca aaaaaaatat ctatactcaa gaggaaatcg aaacattgaa atcggctgtt
    36841 cctatgggga ttgtcaatat tgttgaaggt gtaattccga ttgttatgaa taacttggtt
    36901 ccaggtctca ttgcaacagg tatcggtggt gctgttggtg gtgctgtttc tttgacaatg
    36961 ggtgctgatt ctgccgtgcc atttggtgga gtgcttatgt taccaaccat gactcgtcca
    37021 gtagctggta tttgtgcttt gttagccaac attgtagtca caggacttgt ctacgcgatt
    37081 ttgaaaaaac caataaaaca tacagaacca gttatgactg ttgaagaaga gattgatttg
    37141 tcagatattg aaattttgta agagggtaac gatgtcaaga attgaatttt caccatcttt
    37201 gatgaccatg gatttggaca aattcaaaga gcagattact tttttgaatg ataaagtagc
    37261 atcttatcat atcgatatta tggatggcca ttttgttccc aatattacct tgtctccttg
    37321 gttcattcaa gaagttcaaa aaattagtga cacaccttta tcagttcatc tgatggtcac
    37381 agacccaacc ttttgggtag atcaagttct cgatttacaa tgtgagtata tttgtattca
    37441 tgctgaagtt ctgaatggtc ttgcttttcg tttgattgat aaaattcatg atgcaggtct
    37501 aaaggctggt gttgtcctta atcctgaaac acctgtttct acaatctttc cctacattga
    37561 tttacttgac aaagtaacta ttatgactgt agatccaggt tttgcaggac aacgcttttt
    37621 ggagtctacc ttgtataaaa tccaagaact ccgtcagctt agagttcaga atggttatca
    37681 ctacatcatt gagatggatg gttcttcgag tcgtaagact ttcaaacaaa ttgatgtggc
    37741 aggaccagat atttatgtta taggtcgcag tggattattt ggtttggatg acgatattgc
    37801 caaagcctgg gatatctgtt ctagagatta cgaagaaatg accggaaaaa caatgccaat
    37861 caaataatgg tttgagaaga aatttattag ttaggaggaa tatatgtcac tacaatcagt
    37921 taacgccatt cgttttcttg gcgtagatgc tattaacaaa tctaattctg gtcacccggg
    37981 aatcgtcatg ggtgctgcgc caatggctta tagcctattt acaaagcacc ttagaattac
    38041 acctgagcag ccaaactgga ttaaccgaga tcgctttatc ttgtctgcgg gtcatggatc
    38101 aatgctactg tatgctctct tgcatttaac agggtataac gatgtatcca tggacgagat
    38161 taaaaatttc cggcaatggg gatctaagac acctggtcat cctgaagtga cgcatacgtc
    38221 tggtgtggat gcgacatctg gtccgcttgg tcaggggatt tctactgccg ttggtttcgc
    38281 ccaagcagag cgttttttag ctgctaagta caacaaagat ggttttccta tttttgacca
    38341 ttatacttat gttatcgctg gagacggtga cttcatggaa ggagtgtctg cggaggcggc
    38401 ttcttatgca ggtcatcaag ctttagataa gcttatcgtc ctctacgact ccaacgatat
    38461 ctgcttggat ggtgagacca aagatacttt ctctgaaaat gttcgcgccc gttacgatgc
    38521 ttatggttgg catacagttc tggtagaaga tggaacagat ttagcagcaa tttctacagc
    38581 aattgagacg gccaagtttt ctggtaagcc gagtttgatt gaagtgaaaa cggtaattgg
    38641 ttacggctca cccaataaaa gtggtacaaa tgctgttcat ggtgcaccac taggagcaga
    38701 agaaacagga gcaactcgta agtttttggg atgggattac gatccatttg aagtaccaga
    38761 ggaagtatat tctgatttca agacaaatgt agcggatcgt ggtcaggagg catacgatgc
    38821 ttgggctagt ttggtgtctg attacaaggt tgcttatccc gaagttgcta gtgagattga
    38881 cgctattgta gctggaaaat cccctgtaac cattactgaa aaagacttcc ctgtctatga
    38941 gaatggcttc tctcaagcaa ctcgtaattc gtcccaagat gctattaata cagcagcagc
    39001 agttttacca accttcttag gtggatcggc agacttagct cactccaaca tgacctacat
    39061 caaggcagat ggcttacaag ataaatataa tccattaaac cgcaatattc agtttggggt
    39121 acgtgaattt gccatgggaa caatcctcaa tggaatggct cttcatggtg gtttacgagt
    39181 ttatggcgga accttctttg ttttctctga ctacatcaaa gctgctattc ggctatcagc
    39241 cattcaggag ttgcctgtaa cttatgtctt tacccatgat tcaattgccg ttggtgaaga
    39301 tggtccaact catgaaccag ttgaacattt ggcaggttta cgctcaatgc caaacttgac
    39361 tgttatccgt ccagcggatg cccgtgaaac tcaagcggct tggcatcatg ccttgaccag
    39421 taccaccact ccaactgtca ttgtcttaac ccgtcaaaac ttggtagttg aagaagggac
    39481 agactttggt aaggtcgcta aaggagccta cgtcgtgtat gataccccgg gatttgatac
    39541 tattatcatt gctacaggat ctgaggtcaa tctagctatc aaagctgcta aggaattggt
    39601 tttacaaggt ggtaaagtac gtgtggtatc tatgccctca accgaactat ttgatgctca
    39661 agatgctacc tacaaggaag acattttacc atctaagact cgtcgtcgtg tggccattga
    39721 aatggcagcg acccaaagtt ggtacaagta tgttggtttg gatggcgcgg tcattggtat
    39781 tgacatcttc ggtgcgtctg ccccagctca gactgtgatt gataattatg gatttacggt
    39841 agagaatatc gttgctcaag ttaagtccct atagaaacca attacaatga agatacagct
    39901 gttgtcagac tagcagatgt agtgatagac actaatcaga tgattggtta tttaaaaact
    39961 ataatgagaa tgtaataatt tatctacgaa agttatagta gatagtatac acaatagagt
    40021 ataccctgaa acggttgcga agtacgctaa tcactttgct actgatctag atagtttctt
    40081 taatcaataa acacagcatc cacagattga cttaggatat tgtaagtttt ttgaaagcta
    40141 gagagaaggt ctctaaaatt aaaaaacgca tagtatagga tgttaaaatg aactgacccc
    40201 aaaagttaga cagaaaaaat ctaacttttt ggggtgtttt attatgaaat taa
//
LOCUS       DAVLXH010000014        38688 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00028199
            SAMN33607166-rid17955573.denovo.014, whole genome shotgun sequence.
ACCESSION   DAVLXH010000014 DAVLXH010000000
VERSION     DAVLXH010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607166
            Sequence Read Archive: SRR23725544
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 38688)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38688)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721421.1
            Genome Coverage       :: 115x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:42:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,210
            CDSs (total)                      :: 2,161
            Genes (coding)                    :: 2,023
            CDSs (with protein)               :: 2,023
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 73 of 138
            Pseudo Genes (incomplete)         :: 60 of 138
            Pseudo Genes (internal stop)      :: 40 of 138
            Pseudo Genes (multiple problems)  :: 31 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38688
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607166-rid17955573.denovo.014"
                     /strain="AUSMDU00028199"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1349"
     gene            417..644
                     /locus_tag="VYO11_000799"
     CDS             417..644
                     /locus_tag="VYO11_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1595388.1"
                     /translation="MIFKAFKTKKQRKRQVELLLTVFFDSFLIDLFLHLFGIVPFKLD
                     KILIVSLIIFPIISTSIYAYEKLFEKVFDKD"
     gene            932..3829
                     /gene="nanA"
                     /locus_tag="VYO11_000800"
     CDS             932..3829
                     /gene="nanA"
                     /locus_tag="VYO11_000800"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored neuraminidase NanA"
                     /protein_id="HEV1595389.1"
                     /translation="MNRSVQERKCRYSIRKLSVGAVSMIVGAVVFGTSPVLAQEGASE
                     QPLANETQLSGESSTLTDTEKSQPSSETELSGNKQEQERKDKQEEKIPRDYYARDLEN
                     VETVIEKEDVETNASNGQRVDLSSELDKLKKLENATVHMEFKPDAKAPAFYNLFSVSS
                     ATKKDEYFTMAVYNNTATLEGRGSDGKQFYNNYNDAPLKVKPGQWNSVTFTVEKPTAE
                     LPNGRVRLYVNGVLSRTSLKSGNFIKDMPDVTHVQIGATKRANNTVWGSNLQIRNLTV
                     YNRALTPEEVQKRSQLFKRSDLEKKLPEGAALTEKTDIFESGRNGKPNKDGIKSYRIP
                     ALLKTDKGTLIAGADERRLHSSDWGDIGMVIRRSEDNGKTWGDRVTITNLRDNPKASD
                     PSIGSPVNIDMVLVQDPETKRIFSIYDMFPEGKGIFGMSSQKEEAYKEIDGKTYQILY
                     REGEKEAYTIRENGTVYTPDGKATDYRVVVDPVKPAYSDKGDLYKGDQLLGNIYFTTN
                     KTSPFRIAKDSYLWMSYSDDDGKTWSAPQDITPMVKADWMKFLGVGPGTGIVLRNGPH
                     KGRILIPVYTTNNVSHLNGSQSSRVIYSDDHGKTWHAGEAVNDNRQVDGQKIHSSTMN
                     NERAQNTESTVVQLNNGDVKLFMRGLTGDLQVATSKDGGVTWEKDIKRYPQVKDVYVQ
                     MSAIHTMHEGKEYIILSNAGGPKRENGMVHLARVEENGELTWLKHNPIQKGEFAYNSL
                     QELGNGEYGILYEHTEKGQNAYTLSFRKFNWDFLSKDLISPTEAKVKRTREMGKGEMG
                     KGVIGLEFDSEVLVNKAPTLQLANGKTATFLTQYDSKTLLFAVDKEDIGQEIIGIAKG
                     SIESMHNLPVNLAGARVPGGVNGSKAAVHEVPEFTGGVNGTEPAVHEIAEYKGSDSLV
                     TLTTKEDYTYKAPLAQQALPETGNKESDLLASLGLTAFFLGLFTLGKKREQ"
     gene            4845..5297
                     /locus_tag="VYO11_000801"
     CDS             4845..5297
                     /locus_tag="VYO11_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HEV1595390.1"
                     /translation="MIITKISRLGTYVGVNPHFATLIDFLEKTGLENLTEGSIAIDGN
                     RLFGNCFTYLADGQAGAFFETHQKYLDIHLVLENEEAMAVTSPENVSVTQEYDEEKDI
                     ELYTGKVEQLVHLRAGECLITFPEDLHQPKVRINDEPVKKVVFKVAIS"
     gene            5316..6653
                     /locus_tag="VYO11_000802"
     CDS             5316..6653
                     /locus_tag="VYO11_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HEV1595391.1"
                     /translation="MKKMRKFLCLAGIALAAVALVACSGKKEATTSTEPPTELSGEIT
                     MWHSFTQGPRLESIQKSADAFMQKHPKTKIKIETFSWNDFYTKWTTGLANGNVPDIST
                     ALPNQVMEMVNSDALVPLNDSIKRIGQDKFNETALNEAKIGDDYYSVPLYSHAQVMWI
                     RTDLLKEHNIEVPKTWDQLYEASKKLKEAGVYGLSVPFGTNDLMATRFLNFYVRSGGG
                     SLLTKDLKADLTSQLAQDGIKYWVKLYKEISPQDSLNFNVLQQATLFYQGKTAFDFNS
                     GFHIGGINANSPQLIDSIDAYPIPKIKESDKDQGIETSNIPMVVWKNSKHPEVAKAFL
                     EALYNEEDYVKFLDSTPVGMLPTIKGISDSAAYKENETRKKFKHAEEVITEAVKKGTA
                     IGYENGPSVQAGMLTNQHIIEQMFQDIITNGTDPMKAAKEAEKQLNDLFEAVQ"
     gene            6732..7616
                     /locus_tag="VYO11_000803"
     CDS             6732..7616
                     /locus_tag="VYO11_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV1595392.1"
                     /translation="MVKERNLTRWIFVLPAMIIVGLLFVYPFFSSIFYSFTNKHLIMP
                     NYKFVGLANYKAVLSDPNFFNAFFNSIKWTVFSLVGQVLVGFVLALALHRVRHFKKLY
                     RTLLIVPWAFPTIVIAFSWQWILNGVYGYLPNLIVKLGLMEHTPAFLTDSTWAFLCLV
                     FINIWFGAPMIMVNVLSALQTVPEEQFEAAKIDGASSWQVFKFIVFPHIKVVVGLLVV
                     LRTVWIFNNFDIIYLITGGGPANATTTLPIFAYNLGWGTKLLGRASAVTVLLFIFLVA
                     ICFIYFAIISKWEKEGRK"
     gene            7616..8449
                     /locus_tag="VYO11_000804"
     CDS             7616..8449
                     /locus_tag="VYO11_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEV1595393.1"
                     /translation="MKKKSSIYLDILSHVLLVGATIVAVFPLVWIIISSVKGKGELTQ
                     YPTRFWPEQFTLDYFTHVINDLHFIDNIRNSLIIALATTLIAIIISAMAAYGIVRFFP
                     KLGAIMSRLLVITYIFPPILLAIPYSIAIAKVGLTNSLFGLMMVYLSFSVPYAVWLLV
                     GFFQTVPIGIEEAARIDGANKFVTFYKVVLPIVAPGIVATAIYTFINAWNEFLYALIL
                     INNTGKMTVAVALRSLNGSEILDWGDMMAASVIVVLPSIIFFSIIQNKIASGLSEGSV
                     K"
     gene            8467..10560
                     /gene="nanB"
                     /locus_tag="VYO11_000805"
     CDS             8467..10560
                     /gene="nanB"
                     /locus_tag="VYO11_000805"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="neuraminidase NanB"
                     /protein_id="HEV1595394.1"
                     /translation="MNKRGLYSKLGISVVGISLLMGVPTLIHANELNYGQLSISPIFQ
                     GGSYQLNNKSIDISPLLLDKLSGESQTVVMKFKADEPNSLQALFGLSNSKAGFKNNYF
                     SIFMRDSGEIGVEIRDAQEGINYLFSRPASLWGKHKGQAVENTLVFVSDSKDKTYTMY
                     VNGIEVFSETVDTFLPISNINGIDKATLGAVNREGKEHYLAKGSIDEISLFNKAISDQ
                     EVSTIPLSNPFQLIFQSGDSTQANYFRIPTLYTLSSGRVLSSIDARYGGTHDSKSKIN
                     IATSYSDDNGKTWSEPIFAMKFNDYEEQLVYWPRDNKLKNSQISGSASFIDSSIVEDK
                     KSGKTILLADVMPAGIGNNNANKADSGFKEINGYYYLKLKKNGDNDFRYTVRENGVVY
                     DETTNKPTNYTINDKYEVLEGGKSLTVEQYSVDFDSGSLREKHNGKQVPMNVFYKDSL
                     FKVTPTNYIAMTTSQNRGESWEQFKLLPPFLGEKHNGTYLCPGQGLALKSSNRLIFAT
                     YTSGELTYLISDDSGQTWKKSSASIPFKNATAEAQMVELRDGVIRTFFRTTTGKIAYM
                     TSRDSGETWSEVSYIDGIQQTSYGTQVSAIKYSQLIDGKEAVILSTPNSRSGRKGGQL
                     VVGLVNKEDDSIDWKYHYDIDLPSYGYAYSAITELPNHHIGVLFEKYDSWSRNELHLS
                     NVVQYIDLEINDLTK"
     gene            10573..11676
                     /locus_tag="VYO11_000806"
     CDS             10573..11676
                     /locus_tag="VYO11_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEV1595395.1"
                     /translation="MVKYGVVGAGYFGAELARYMQKNDGAEITLLYDPDNAEAIAEEL
                     GAKVASSLDELVSSDEVDCVIVATPNNLHKEPVIKAAQHGKNVFCEKPIALSYQDCRE
                     MVDACKENNVTFMAGHIMNFFNGVHHAKELINQGVIGDVLYCHTARNGWEEQQPSVSW
                     KKIREKSGGHLYHHIHELDCVQFLMGGMPETVTMTGGNVAHEGEHFGDEDDMIFVNME
                     FSNKRFALLEWGSAYRWGEHYVLIQGSKGAIRLDLFNCKGTLKLDGQESYFLIHESQE
                     EDDDRTRIYHSTEMDGAIAYGKPGKRTPLWLSSVIDKEMRYLHEIMEGAPVSEEFAKL
                     LTGEAALEAIATADACTQSMFEDRKVKLSEIVK"
     gene            11850..12548
                     /locus_tag="VYO11_000807"
     CDS             11850..12548
                     /locus_tag="VYO11_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HEV1595396.1"
                     /translation="MPQISKEALIEQIKDGIIVSCQALPHEPLYTEAGGVIPLLVKAA
                     EQGGAVGIRANSVRDIKEIKEVTKLPIIGIIKRDYPPQEPFITATMKEVDELAELDIE
                     VIALDCTKRERYDGLEIQEFIRQVKEKYPNQLLMADTSIFEEGLAAVEAGIDFVGTTL
                     SGYTSYSPKVDGPDFELIKKLCDAGVDVIAEGKIHTPEQAKQILEYGVRGIVVGGAIT
                     RPKEITERFVASLK"
     gene            12567..14084
                     /locus_tag="VYO11_000808"
     CDS             12567..14084
                     /locus_tag="VYO11_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000477452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEV1595397.1"
                     /translation="MFKVLQKVGKAFMLPIAILPAAGLLLGIGGALSNPTTIATYPIL
                     DNSIFQSIFQVMSSAGEVVFSNLSLLLCVGLCIGLAKRDKGTAALAGVTGYLVMTATI
                     KALVKLFMAEGSAIDTGVIGALVVGIVAVYLHNRYNNIQLPSALGFFGGSRFVPIVTS
                     FSSILIGFVFFVIWPPFQQLLVSTGGYISQAGPIGTFLYGFLMRLSGAVGLHHIIYPM
                     FWYTELGGVETVAGQTVVGAQKIFFAQLADPAHSGLFTEGTRFFAGRFSTMMFGLPAA
                     CLAMYHSVPKNRRKKYAGLFFGVALTSFITGITEPIEFMFLFVSPVLYVVHAFLDGVS
                     FFIADVLNISIGNTFSGGVIDFTLFGILQGNAKTNWVLQIPIGLIWSVLYYIIFRWFI
                     TQFNVLTPGRGEEVDSKEISESADSTSNTADYLKQDSLQIIRALGGSNNIEDVDACVT
                     RLRVAVKEVNQVDKALLKQIGAVDVLEVKGGIQAIYGAKAILYKNSINEILGVDD"
     gene            14209..15537
                     /locus_tag="VYO11_000809"
     CDS             14209..15537
                     /locus_tag="VYO11_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV1595398.1"
                     /translation="MKFRKLACTVLAGAAVLGLAACGNSGGSKDAAKSGGDGAKTEIT
                     WWAFPVFTQEKTGDGVGTYEKSIIEAFEKANPDIKVKLETIDFKSGPEKITTAIEAGT
                     APDVLFDAPGRIIQYGKNGKLAELNDLFTDEFVKDVNNENIVQASKAGDKAYMYPISS
                     APFYMAMNKKMLEDAGVANLVKEGWTTDDFEKVLKALKDKGYTPGSLFSSGQGGDQGT
                     RAFISNLYSGSVTDEKVSKYTTDDPKFVKGLEKATSWIKDNLINNGSQFDGGADIQNF
                     ANGQTSYTILWAPAQNGIQAKLLEASKVEVVEVPFPSDEGKPALEYLVNGFAVFNNKD
                     DKKVAASKKFIQFIADDKEWGPKDVVRTGAFPVRTSFGKLYEDKRMETISGWTQYYSP
                     YYNTIDGFAEMRTLWFPMLQSVSNGDEKPADALKAFTEKANETIKKAMKQ"
     gene            15789..16655
                     /locus_tag="VYO11_000810"
     CDS             15789..16655
                     /locus_tag="VYO11_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV1595399.1"
                     /translation="MRETVISYAFLAPVLFFFVIFVLAPMVMGFITSFFNYSMTKFEF
                     VGLDNYIRMFKDPVFTKSLINTVILVIGSVPVVVLFSLFVASQTYHQNVIARSFYRFV
                     FFLPVVTGSVAVTVVWKWIYDPLSGILNFVLKSSHIISQNISWLGDKNWALMAIMIIL
                     LTTSVGQPIILYIAAMGNIDNSLVEAARVDGATEFQVFWKIKWPSLLPTTLYIAIITT
                     INSFQCFALIQLLTSGGPNYSTSTLMYYLYEKAFQLTEYGYANTIGVFLAVMIAIVSF
                     VQFKVLGNDVEY"
     gene            16671..17510
                     /locus_tag="VYO11_000811"
     CDS             16671..17510
                     /locus_tag="VYO11_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEV1595400.1"
                     /translation="MQSTEKKPLTAFTVISTIILLLLTVLFIFPFYWILTGAFKSQPD
                     TIVIPPQWFPKMPTMENFQQLMVQNPALQWMWNSVFISLVTMFLVCATSSLAGYVLAK
                     KRFYGQRILFAIFIAAMALPKQVVLVPLVRIVNFMGIHDTLWAVILPLIGWPFGVFLM
                     KQFSENIPTELLESAKIDGCGEIRTFWSVAFPIVKPGFAALAIFTFINTWNDYFMQLV
                     MLTSRNNLTISLGVATMQAEMATNYGLIMAGAALAAVPIVTVFLVFQKSFTQGITMGA
                     VKG"
     gene            17782..18234
                     /locus_tag="VYO11_000812"
     CDS             17782..18234
                     /locus_tag="VYO11_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HEV1595401.1"
                     /translation="MIFDDLKNITFYKGIHPNLDKAIDYLYQHRKDSFELGKYEIDGD
                     KVFLVVQENVLNQVENNQFEHHKNYADLHLLVEGHEYSSYGSRIKDEAVAFDEATDIG
                     FVHCHEHYPLLLGYHNFAIFFPGEPHQPTGYAGMEEKVRKYLFKILID"
     gene            18331..18675
                     /locus_tag="VYO11_000813"
     CDS             18331..18675
                     /locus_tag="VYO11_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1595402.1"
                     /translation="MVSSKHAARASFLDGQGITVDEMSWIINGIVNALIGRYIKLGTY
                     AAKYGISIARSILSRAAATAAARVGLLTKISGWILRVAVNVADVYGNFANNIAAAWDA
                     YDKIPNNGRINF"
     gene            18959..19603
                     /locus_tag="VYO11_000814"
     CDS             18959..19603
                     /locus_tag="VYO11_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000057467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HEV1595403.1"
                     /translation="MAQKGVSLIKAAFDTDNFLMRFSEKVLDIVTANLLFVVSCLPIV
                     TIGVAKISLYETMFEVKKSRRVPVFKIYLRSFKQNLKLGLQLGLMELGIVFLTLSDLY
                     LFWGQTALPFQLLKAICLGILIFLTIVMLASYPIAARYDLSWKEILQKGLMLASFNFP
                     WFFLMLAILVLIVMVLYLSAFSLLLGGSVFLLFGFGLLVFIQTGLMEKIFAKYQ"
     gene            19772..20689
                     /locus_tag="VYO11_000815"
     CDS             19772..20689
                     /locus_tag="VYO11_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HEV1595404.1"
                     /translation="MSDLKKYEGVIPAFYACYDDQGEVSPERTRALVQYFIDKGVQGL
                     YVNGSSGECIYQSVEDRKLILEEVMAVAKGKLTIIAHVACNNTKDSMELARHAESLGV
                     DAIATIPPIYFRLPEYSVAKYWNDISSAAPNTDYVIYNIPQLAGVALTPSLYTEMLKN
                     PRVIGVKNSSMPVQDIQTFVSLGGEDHIVFNGPDEQFLGGRLMGARAGIGGTYGAMPE
                     LFLKLNQLIADKDLETARELQYAINAIIGKLTSAHGNMYGVIKEVLKINEGLNIGSVR
                     SPLTPVTEEDRPVVEAAAALIRETKERFL"
     gene            20707..21591
                     /locus_tag="VYO11_000816"
     CDS             20707..21591
                     /locus_tag="VYO11_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEV1595405.1"
                     /translation="MTYYVAIDIGGTNIKYGLVDQEGQLLESHEMPTEAHKGGPHILQ
                     KTKDIVASYLEKGPVAGVAISSAGMVDPDKGEIFYAGPQIPNYAGTQFKKEIEESFTI
                     PCEIENDVNCAGLAEAVSGSGKGASVTLCLTIGTGIGGCLIMDRKVFHGFSNSACEVG
                     YMHMQDGAFQDLASTTALVKYVAEAHGEDVDQWNGRRIFKEATEGNKICMEGIDRMVD
                     YLGKGLANICYVANPEVVILGGGIMGQEAILKPKIRTALKEALVPSLAEKTRLEFAHH
                     QNTAGMLGAYYHFKTKQS"
     gene            complement(21607..22458)
                     /locus_tag="VYO11_000817"
     CDS             complement(21607..22458)
                     /locus_tag="VYO11_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HEV1595406.1"
                     /translation="MDKPDIATIIDSHFEEMTDLEQEIARYFLQAETITDDLSSQQVT
                     QKLHISQAALTRFAKKCGFTGYREFIFQYQHQAENQANQVSKHSPLTKRVLRSYSNMR
                     EQTQDLIDEIQLERIAQLIEDAERIYFFGTGSSGLVAREMKLRFMRLGVVCEALTDQD
                     GFAWTTSIMDENCLVLGFSLSGSTPSILDSLLDAKEMGAKTVLFTSVPNKDSQTYTET
                     VLVATHSQPSYIQRISAQLPMLFFIDLIYAYFLEINRESKEKIFNSYWENKKLNGYRR
                     QKRVRKS"
     gene            22658..24715
                     /gene="pbp2b"
                     /locus_tag="VYO11_000818"
     CDS             22658..24715
                     /gene="pbp2b"
                     /locus_tag="VYO11_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2B"
                     /protein_id="HEV1595407.1"
                     /translation="MRLICMRKFNSHSIPIRLNLLFSIVILLFMAIIGRLLYMQVLNK
                     DFYEKKLASASQTKITSSSARGEIYDASGKPLVENTLKQVVSFTRSNKMTATDLKETA
                     KKLLTYVSISSPNLTERQLADYYLADPEIYKKTVEALPSEKRLDSDGNRLSESELYNN
                     AVDSVQTSQLNYTEDEKKEIYLFSQLNAVGNFATGTIATDPLNDSQVAVIASISKEMP
                     GISISTSWDRKVLETSLSSIVGSVSSEKAGLPAEEAEAYLKKGYSLNDRVGTSYLEKQ
                     YEETLQGKRSVKEIHLDKYGNMESVDTIEEGSKGNNIKLTIDLAFQDSVDALLKSYFN
                     SELENGGAKYSEGVYAVALNPKTGAVLSMSGIKHDLKTGELTPDSLGTVTNVFVPGSV
                     VKAATISSGWENGVLSGNQTLTDQPIVFQGSAPINSWYTQAYGSFPITAVEALEYSSN
                     AYMVQTALGIMGQTYQPNMFVLTNNLESAMGKLRSTFAEYGLGASTGIDLPDESTGFI
                     PKEYNFANYITNAFGQFDNYTPMQLAQYVGTIANNGVRIAPHIVEGIYGNNEQGGLGN
                     LIQSVESKEMNKINISESDVSILQQGFYQVSHGGSALTTGRAFSNGASVSISGKTGTA
                     ESYVEGGQEANNTNAVAYAPSDNPQIAVAVVFPHNTNLTNGVGPSIARDIINLYNQHH
                     PMN"
     gene            24726..25322
                     /gene="recR"
                     /locus_tag="VYO11_000819"
     CDS             24726..25322
                     /gene="recR"
                     /locus_tag="VYO11_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HEV1595408.1"
                     /translation="MLYPTPIAKLIDSYSKLPGIGIKTATRLAFYTIGMSDDDVNEFA
                     KNLLSAKRELTYCSICGRLTDDDPCSICTDPTRDQTTILVLEDSRDVAAMENIQEYHG
                     LYHVLHGLISPMNGISPDDINLKSLMTRLMDSEVSEVIVATNATADGEATSMYLSRLL
                     KPAGIKVTRLARGLAVGADIEYADEVTLLRAIENRTEL"
     gene            25498..26541
                     /locus_tag="VYO11_000820"
     CDS             25498..26541
                     /locus_tag="VYO11_000820"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HEV1595409.1"
                     /translation="MKQTIILLYGGRSAEREVSVLSAESVMRAVDYDRFTVKTFFISQ
                     SGDFIKTQEFSHDPGQEDRLMTNETIDWDKKVAPSAIYEEGAVVFPVLHGPMGEDGSV
                     QGFLEVLKMPYVGCNILSSSLAMDKITTKRVLESAGIAQVPYVAIVEGDDVTAKIAEV
                     EEKLAYPVFTKPSNMGSSVGISKSENQEELRQALELAFRYDSRVLVEQGVNAREIEVG
                     LLGNYDVKSTLPGEVVKDVAFYDYDAKYIDNKITMDIPAKISDDVVAVMRQNAETAFR
                     AIGGLGLSRCDFFYTDKGEIFLNELNTMPGFTQWSMYPLLWDNMGISYPELIERLVDL
                     AKESFDKREAHLI"
     gene            26625..27998
                     /locus_tag="VYO11_000821"
     CDS             26625..27998
                     /locus_tag="VYO11_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HEV1595410.1"
                     /translation="MKLTIHEIAQVVGAKNDISIFEDTQLEKAEFDSRLIGTGDLFVP
                     LKGARDGHDFIETAFENGAAVTLSEKEVSNHPYILVDDVLTAFQSLASYYLEKTTVDV
                     FAVTGSNGKTTTKDMLAHLLSTRYKTYKTQGNYNNEIGLPYTVLHMPEGTEKLVLEMG
                     QDHLGDIHLLSELARPKTAIVTLVGEAHLAFFKDRSEIAKGKMQIADGMASGSLLLAP
                     ADPIVEDYLPTDKKVVRFGQGAELEITDLVERKDSLTFKANFLEQVLDLPVTGKYNAT
                     NAMIASYVALQEGVSEEQIHQAFQGLELTRNRTEWKKAANGADILSDVYNANPTAMKL
                     ILETFSAIPANEGGKKIAVLADMKELGDQSIQLHNQMILSLSPDVLDIVIFYGEDIAE
                     LAQLASQMFPIGHVYYFKKTEDQDQFEDLVKQVKESLGAHDQILLKGSNSMNLAKLVE
                     SLENEDK"
     gene            27985..28596
                     /locus_tag="VYO11_000822"
     CDS             27985..28596
                     /locus_tag="VYO11_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEV1595411.1"
                     /translation="MKTSDFVKYLQRMIALTDTGLTFTKDPFDRERYEDLRDLLSEML
                     NQASDLDSEEVAEVLKPTSAYATPLMDVRAWIVEDEKICLVRGQGEDSWALPGGFGEV
                     GYSPTENILKEIEEETGFKAKVERLLAVFDTNRFQLQSKQYAKFVFECKLLDGQFQEN
                     QEIADLQFFAIDQLPNLSEKRITKEQIEILWQVYQGQREQYLD"
     gene            28687..29391
                     /locus_tag="VYO11_000823"
     CDS             28687..29391
                     /locus_tag="VYO11_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001055242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02206 family membrane protein"
                     /protein_id="HEV1595412.1"
                     /translation="MNLWDIFFTTQATEPPKFDLFWYVSLFTLLALTFYTAHRYREKK
                     VYQRFFQILQTVQLILLYGWYWVNHMPLSESLPFYHCRMAMFVVLLLPGQSKYKQYFA
                     LLGTFGTLAAFVYPVPDAYPFPHITILSFIFGHLALLGNSLVYLLRQYNARLLDVKGI
                     FLMTFALNALIFVVNLVTGGDYGFLTKPPLVGDHGLVANYLLVSIVLVATISLTKKIL
                     EFFLAQEAEKMIAKEA"
     gene            29610..30983
                     /gene="ftsA"
                     /locus_tag="VYO11_000824"
     CDS             29610..30983
                     /gene="ftsA"
                     /locus_tag="VYO11_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000090410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HEV1595413.1"
                     /translation="MAREGFFTGLDIGTSSVKVLVAEQRNGELNVIGVSNAKSKGVKD
                     GIIVDIDAAATAIKSAISQAEEKAGISIKSVNVGLPGNLLQVEPTQGMIPVTSDTKEI
                     TDQDVENVVKSALTKSMTPDREVITFIPEEFIVDGFQGIRDPRGMMGVRLEMRGLLYT
                     GPRTILHNLRKTVERAGVQVENVIISPLAMVQSVLNEGEREFGATVIDMGAGQTTVAT
                     IRNQELQFTHILQEGGDYVTKDISKVLKTSRKLAEGLKLNYGEAYPPLASKETFQVEV
                     IGEVEAVEVTEAYLSEIISARIKHILEQIKQELDRRRLLDLPGGIVLIGGNAILPGMV
                     ELAQEVFGVRVKLYVPNQVGIRNPAFAHVISLSEFAGQLTEVNLLAQGAIKGENDLSH
                     QPISFGGMLQKTAQFVQSTPVQPAPAPEVEPVAPTEPMADFQQASQNKPKLADRFRGL
                     IGSMFDE"
     gene            31000..32259
                     /gene="ftsZ"
                     /locus_tag="VYO11_000825"
     CDS             31000..32259
                     /gene="ftsZ"
                     /locus_tag="VYO11_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000144288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HEV1595414.1"
                     /translation="MTFSFDTAAAQGAVIKVIGVGGGGGNAINRMVDEGVTGVEFIAA
                     NTDVQALSSTKAETVIQLGPKLTRGLGAGGQPEVGRKAAEESEETLTEAISGADMVFI
                     TAGMGGGSGTGAAPVIARIAKDLGALTVGVVTRPFGFEGSKRGQFAVEGINQLREHVD
                     TLLIISNNNLLEIVDKKTPLLEALSEADNVLRQGVQGITDLITNPGLINLDFADVKTV
                     MANKGNALMGIGIGSGEERVVEAARKAIYSPLLETTIDGAEDVIVNVTGGLDLTLIEA
                     EEASQIVNQAAGQGVNIWLGTSIDESMRDEIRVTVVATGVRQDRVEKVVAPQARSATN
                     YRETVKPAHSHGFDRHFDMAETVELPKQNPRRLEPTQASAFGDWDLRRESIVRTTDSV
                     VSPVERFEAPISQDEDELDTPPFFKNR"
     gene            32264..32935
                     /locus_tag="VYO11_000826"
     CDS             32264..32935
                     /locus_tag="VYO11_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HEV1595415.1"
                     /translation="MNVKENTELVFREVAEASLSAHRESGSVSVIAVTKYVDVPTAEA
                     LLPLGVHHIGENRVDKFLEKYEALKDRDVTWHLIGTLQRRKVKDVIQYVDYFHALDSV
                     KLAGEIQKRSDRVIKCFLQVNISKEESKHGFSREELLEILPELARLDKIEYVGLMTMA
                     PFEASSEQLKEIFKAAQDLQREIQEKQIPTMPMTELSMGMSRDYKEAIQFGSTFVRIG
                     TSFFK"
     gene            32945..33484
                     /locus_tag="VYO11_000827"
     CDS             32945..33484
                     /locus_tag="VYO11_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HEV1595416.1"
                     /translation="MSLKDRFDRFIDYFTEDEDSSLPYEKRDEPVFTSVNSSQEPALP
                     MNQPSQSAGTKENNITRLHARQQELANQSQRATDKVIIDVRYPRKYEDATEIVDLLAG
                     NESILIDFQYMTEVQARRCLDYLDGACHVLAGNLKKVASTMYLLTPVNVIVNVEDIRL
                     PDEDQQGEFGFDMKRNRVR"
     gene            33484..33747
                     /locus_tag="VYO11_000828"
     CDS             33484..33747
                     /locus_tag="VYO11_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HEV1595417.1"
                     /translation="MIFLIRMIYNAVDIYSLILVTFAVMSWFPGAYESSLGRWIVALV
                     KPVLAPLQRLPLQIAGLDLSVWVAIVLVRFLGENLVRFLAMIG"
     gene            33744..34529
                     /locus_tag="VYO11_000829"
     CDS             33744..34529
                     /locus_tag="VYO11_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HEV1595418.1"
                     /translation="MNKGIYQHFSIEDRPFLDKGMEWIKKVEDSYAPFLTPFINPHQE
                     KLLKILAKTYGLACSSSGEFVSSEYVRVLLYPDYFQPEFSDFEISLQEIVYSNKFEHL
                     THAKILGTVINQLGIERKLFGDILVDEERAQIMINQQFLLLFQDGLKKIGRIPVSLEE
                     RPFTEKIDKLEQYRELDLSVSSFRLDVLLSNVLKLSRNQANQLIEKKLVQVNYHVVDK
                     SDYTVQVGDLISVRKFGRLRLLQDKGQTKKEKKKITVQLLLSK"
     gene            34538..35326
                     /gene="divIVA"
                     /locus_tag="VYO11_000830"
     CDS             34538..35326
                     /gene="divIVA"
                     /locus_tag="VYO11_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIVA"
                     /protein_id="HEV1595419.1"
                     /translation="MPITSLEIKDKTFGTRFRGFDPEEVDEFLDIVVRDYEDLVRANH
                     DKNLRIKSLEERLSYFDEIKDSLSQSVLIAQDTAERVKQAAHERSNNIIHQAEQDAQR
                     LLEEAKYKANEILRQATDNAKKVAVETEELKNKSRVFHQRLKSTIESQLAIVESSDWE
                     DILRPTATYLQTSDEAFKEVVSEVLGEPIPAPIEEEPIDMTRQFSQAEMEELQARIEV
                     ADKELSEFEAQIKQEVETPTPVVSPQVEEEPLLIQLAQCMKNQK"
     gene            35674..38466
                     /locus_tag="VYO11_000831"
     CDS             35674..38466
                     /locus_tag="VYO11_000831"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HEV1595420.1"
                     /translation="MKLKDTLNLGKTEFPMRAGLPTKEPVWQKEWEDAKLYQRRQELN
                     QGKPHFTLHDGPPYANGNIHVGHAMNKISKDIIVRSKSMSGFYAPFIPGWDTHGLPIE
                     QVLSKQGVKRKEMDLVEYLKLCREYALSQVDKQREDFKRLGVSGDWENPYVTLTPDYE
                     AAQIRVFGEMANKGYIYRGAKPVYWSWSSESALAEAEIEYHDLVSTSLYYANKVKDGK
                     GVLDTDTYIVVWTTTPFTITASRGLTVGADIDYVLVQPAGEARKFVVAAELLTSLSEK
                     FGWADVQVLETYRGQELNHIVTEHPWDTAVEELVILGDHVTTDSGTGIVHTAPGFGED
                     DYNVGIANNLEVAVTVDERGIMMKNAGPEFEGQFYEKVVPTVIEKLGNLLLAQEEISH
                     SYPFDWRTKKPIIWRAVPQWFASVSKFRQEILDEIEKVKFHSEWGKVRLYNMIRDRGD
                     WVISRQRAWGVPLPIFYAEDGTAIMVAETIEHVAQLFEEHGSSIWWERDAKDLLPEGF
                     THPGSPNGEFKKETDIMDVWFDSGSSWNGVVVNRPELTYPADLYLEGSDQYRGWFNSS
                     LITSVANHGVAPYKQILSQGFALDGKGEKMSKSLGNTIAPSDVEKQFGAEILRLWVTS
                     VDSSNDVRISMDILSQVSETYRKIRNTLRFLIANTSDFNPAQDTVAYDELRSVDKYMT
                     IRFNQLVKTIRDAYADFEFLTIYKALVNFINVDLSAFYLDFAKDVVYIEGAKSLERRQ
                     MQTVFYDILVKITKLLTPILPHTAEEIWSYLEFETEDFVQLSELPEVQTFANQEEILD
                     TWAAFMDFRGQAQKALEEARNAKVIGKSLEAHLTVYPNEVVKTLLEAVNSNVAQLLIV
                     SELTIAEGPAPEAALSFEDVAFTVERAAGEVCDRCRRIDPTTAERSYQAVICDHCASI
                     VEENFAEAVAEGFEEK"
BASE COUNT        12067 a         6790 c         8385 g        11446 t
ORIGIN      
        1 cgtcagttct atccacaacc tcaaaacagt gttttgagct gactttgtca gtcttatcta
       61 caacctcaaa acagtgtttt gagcatcatg cggctagctt cttagtttgc tctttgattt
      121 tcattgagta taaaaacaga tgagtttctg ttttcttttt atggactata aatgttcagc
      181 tgaaactact ttcaaggaca ttattatata aaagaatttt ttgaaactaa aatctactat
      241 attacactat attgaaagcg ttttaaaaat gaggtataat aaatttacta acacttataa
      301 aaagtgatag aatctatctt tatgtatatt taaagataga ttgctgtaaa aatagtagta
      361 gctatgcgaa ataacagata gagagaaggg attgaagctt agaaaagggg aataatatga
      421 tatttaaggc attcaagaca aaaaagcaga gaaaaagaca agttgaacta cttttgacag
      481 tttttttcga cagttttctg attgatttat ttcttcactt atttgggatt gtccccttta
      541 agctggataa gattctgatt gtgagcttga ttatatttcc cattatttct acaagtattt
      601 atgcttatga aaagctattt gaaaaagtgt tcgataagga ttgagcagga agtatggtgt
      661 aaatagcata agctgatgtc catcatttgc ttataaagag atagtttagt ttaattgcag
      721 cggtgtcctg gtagataaac tagattggca ggagtctgat tggagaaagg agaggggaaa
      781 tttggcacca atttgagata gtttgtttag ttcatttttg tcatttaaat gaactgtagt
      841 aaaagaaaat taataaaaga caaactaagt gcattttctg gaataaatgt cttatttcag
      901 aaatcgggat atagatatag agaggatcag tatgaatcgg agtgttcaag aacgtaagtg
      961 tcgttatagc attaggaaac tatcggtagg agcggtttct atgattgtag gagcagtggt
     1021 atttggaacg tctcctgttt tagctcaaga aggggcaagt gagcaacctc tggcaaatga
     1081 aactcaactt tcgggggaga gctcaaccct aactgataca gaaaagagcc agccttcttc
     1141 agagactgaa ctttctggca ataagcaaga acaagaaagg aaagataagc aagaagaaaa
     1201 aattccaaga gattactatg cacgagattt ggaaaatgtc gaaacagtga tagaaaaaga
     1261 agatgttgaa accaatgctt caaatggtca gagagttgat ttatcaagtg aactagataa
     1321 actaaagaaa cttgaaaacg caacagttca catggagttt aagccagatg ccaaggctcc
     1381 agcattctat aatctctttt ctgtgtcaag tgctactaaa aaagatgagt acttcactat
     1441 ggcagtttac aataatactg ctactctaga ggggcgtggt tcggatggga aacagtttta
     1501 caataattac aacgatgcac ccttaaaagt taaaccaggt cagtggaatt ctgtgacttt
     1561 cacagttgaa aaaccgacag cagaattgcc aaatggtcga gttcgcctct acgtaaacgg
     1621 ggtattatct cgaacaagtc tgaaatctgg caatttcatt aaagatatgc cagatgtaac
     1681 gcatgtgcaa atcggagcaa ccaagcgtgc caacaatacg gtttgggggt caaatctaca
     1741 gattaggaat ctcactgtgt ataatcgtgc tttaacacca gaagaggtac aaaaacgtag
     1801 tcaacttttt aaacgctcag atttagaaaa aaaactacct gaaggagcgg ctttaacaga
     1861 gaaaacggac atattcgaaa gcgggcgtaa cggtaaacca aataaagatg gaatcaagag
     1921 ttatcgtatt ccagcacttc tcaagacaga taaaggaact ttgatcgcag gtgcagatga
     1981 acgccgtctc cattcgagtg actggggtga tatcggtatg gtcatcagac gtagtgaaga
     2041 taatggtaaa acttggggtg accgagtaac cattaccaac ttacgtgaca atccaaaagc
     2101 ttctgaccca tcgatcggtt caccagtgaa tatcgatatg gtgttggttc aagatcctga
     2161 aaccaaacga atcttttcta tctatgacat gttcccagaa gggaagggaa tctttggaat
     2221 gtcttcacaa aaagaagaag cctacaaaga aatcgatgga aaaacctatc aaatcctcta
     2281 tcgtgaggga gaaaaggaag cttataccat tcgagaaaat ggtactgtct atacaccaga
     2341 tggtaaggcg acagactatc gcgttgttgt agatcctgtt aaaccagcct atagtgacaa
     2401 gggtgatcta tacaagggtg accaattact aggaaatatc tacttcacaa caaacaaaac
     2461 ttctccattt agaattgcca aggatagcta tctatggatg tcctacagtg atgacgacgg
     2521 gaagacatgg tcagcgcctc aagatattac tccgatggtc aaagccgatt ggatgaaatt
     2581 cttgggtgta ggtcctggaa caggaattgt acttcggaat gggcctcaca agggacggat
     2641 tttgataccg gtttatacga ctaataatgt atctcactta aatggctcgc aatcttctcg
     2701 tgtcatctat tcagatgatc atggaaaaac ttggcatgct ggagaagcgg tcaacgataa
     2761 ccgtcaggta gacggtcaaa agatccactc ttctacgatg aacaatgaac gtgcgcaaaa
     2821 tacagaatca acggtggtac aactaaacaa tggagatgtt aaactcttta tgcgtggttt
     2881 gactggagat cttcaggttg ctacaagtaa agacggagga gtgacttggg agaaggatat
     2941 caaacgttat ccacaggtta aagatgtcta tgttcaaatg tctgctatcc atacgatgca
     3001 cgaaggaaaa gaatacatca tcctcagtaa tgcaggtgga ccgaaacgtg aaaatgggat
     3061 ggtccacttg gcacgtgtcg aagaaaatgg tgagttgact tggctcaaac acaatccaat
     3121 tcaaaaagga gagtttgcct ataattcgct ccaagaatta ggaaatgggg agtatggcat
     3181 cttgtatgaa catactgaaa aaggacaaaa tgcctatacc ctatcattta gaaaatttaa
     3241 ttgggacttt ttgagcaaag atctgatttc tcctaccgaa gcgaaagtga agcgaactag
     3301 agagatgggc aaaggagaga tgggcaaagg agttattggc ttggagttcg actcagaagt
     3361 attggtcaac aaggctccaa cccttcaatt ggcaaatggt aaaacagcga ctttcctaac
     3421 ccagtatgat agcaagacct tgttgtttgc agtagataag gaagatatcg gacaggaaat
     3481 tattggtata gctaaaggaa gcatcgaaag tatgcataat cttcctgtaa atctagcagg
     3541 tgccagagtt cctggcggag taaatggtag caaagcagcg gtgcatgaag ttccagaatt
     3601 tacaggggga gttaatggta cagagccagc tgttcatgaa atcgcagagt ataagggatc
     3661 tgattcgctt gtaactctta ctacaaaaga agattatact tacaaagctc ctcttgctca
     3721 gcaggcactt cctgaaacag gaaacaagga gagtgacctc ctagcttcac taggactaac
     3781 agctttcttc cttggtctgt ttacgctagg gaaaaagaga gaacaataag agaagaattc
     3841 taaacatttg attttgtaaa aatagaagga gatagcaggt tttcaagcct gctatctttt
     3901 tttgatgaca ttcaagctga tacgaaatca taagaggtct gaaactactt tcagggtagt
     3961 ctgttctata aaatatagta gattgaaata agatgtgaac aactctacca ggaaagtcaa
     4021 attaatttat agaattattt tagcagtcaa ggtgtactgt tatagattca atatattatg
     4081 tgactattaa ccttgtcttc tcctaaaatt gactttcttg ttttcttatc ttgtccactc
     4141 gaaacaagta ttgtaagaat ttgattattt ttgaaagtac ttttaatata cttgatatag
     4201 ttaaaaaaga tttgaaacta aattccaaat tagaaaaaga cttgaaatac taaaaaaaaa
     4261 aaagtatact ctaattgaaa acggtaacaa aactaattta gagaatgaaa tatagagtat
     4321 ttctctctta aaagtttttg gtgaaacgag atgtagaaag gagatttagc caaagagtct
     4381 attagtgcta gaataataga ttagaattat tttagaaaaa cgaagtgagc agcttataaa
     4441 ttcaagtccc caaatagatt catactagta tcttttgcaa aaaataaagg gcgacttcct
     4501 tcatgaatat caatttcatc tataaggaag gtagctaatt gaactaactt atttattctg
     4561 tttgtcgcta gaaaaatcag acctccttgt gaagattgag gagatactga atgaaaatca
     4621 aagaagaaac tagcaagcta gtagcagatt gcccaaaaca ccgctttgag gttgtagata
     4681 agactgacct atataatcca aggtgaagcg actgtggttt gaagagattt tcaaagagta
     4741 taggctagag agtagtgttt ttatgtcctt ctagtagaaa atgctagaca gaagaatggg
     4801 gaacttggat aggaaaaata gattgagaaa ggaggttaga agagatgatt attacaaaaa
     4861 ttagccgttt aggaacttat gtgggagtaa atccacattt tgcaacatta atagattttc
     4921 tagaaaaaac aggactagaa aatttaacag aaggttcgat tgctatcgat ggtaatcgat
     4981 tgtttgggaa ttgctttact tatctagcag atggtcaagc aggggctttc tttgaaacac
     5041 accaaaaata tttggatatt catttagttt tggaaaacga agaagccatg gctgttacat
     5101 cgccggaaaa tgtaagcgtt acccaagaat atgatgaaga gaaggatatt gaattataca
     5161 cagggaaagt ggaacagttg gttcatttga gagctggtga atgcctcatc acttttccag
     5221 aagatttaca tcaacccaag gttcgtataa atgatgaacc tgtgaaaaaa gttgtcttta
     5281 aagttgcgat ttcttaatgt agaaagagaa gaacgatgaa aaaaatgaga aagtttttat
     5341 gtctagctgg aattgcgcta gcggctgttg ccttggtagc ttgttcagga aaaaaagaag
     5401 ctacaactag tactgaacca ccaacagaat tatctggtga gattacaatg tggcactcct
     5461 ttactcaagg accccgttta gaaagtattc aaaaatcagc agatgctttc atgcaaaagc
     5521 atccaaaaac gaaaatcaag attgaaacat tttcttggaa tgacttctat actaaatgga
     5581 ctacaggttt agcaaatgga aatgtgccag atatcagtac agctcttcct aaccaagtaa
     5641 tggaaatggt caactcagat gctttggttc cgctaaatga ttctatcaag cgtattggac
     5701 aagataaatt taacgaaact gccttaaatg aagcaaaaat cggagatgat tactactctg
     5761 ttcctcttta ttcacatgca caagtcatgt ggattagaac agatttgtta aaagaacata
     5821 atattgaggt tcctaaaact tgggatcaac tctatgaagc ttctaaaaaa ttgaaagaag
     5881 ctggagttta tggcttgtct gttccgtttg gaacaaatga cttaatggca acacgtttct
     5941 tgaacttcta cgtacgtagt ggtggaggaa gcctcttaac aaaagatctt aaagcagact
     6001 tgacaagcca acttgctcaa gatggtatta aatactgggt taaattgtat aaagaaatct
     6061 cacctcaaga ttctttgaac tttaatgtcc ttcaacaagc taccttgttc tatcaaggaa
     6121 aaacagcatt tgactttaac tctggcttcc atatcggagg aattaatgcc aacagtcctc
     6181 aattgattga ttcgattgat gcttatccta ttccaaaaat caaagagtct gataaagacc
     6241 aaggaattga aacctcaaac attccaatgg ttgtttggaa aaattcaaaa catccagaag
     6301 ttgctaaagc attcttagaa gcactttata atgaagaaga ctacgttaaa ttccttgatt
     6361 caactccagt aggtatgttg ccaactatta aggggattag cgattctgca gcctataaag
     6421 aaaatgaaac tcgtaagaag tttaaacatg ctgaagaagt aattactgaa gctgttaaaa
     6481 aaggtactgc tattggttat gaaaatggac caagtgtaca agctggtatg ttgactaacc
     6541 aacacattat tgaacaaatg ttccaagata tcattacaaa tggaacagat cctatgaaag
     6601 cagcaaaaga agcagaaaaa caattaaacg atttatttga ggctgttcag tagatgtaaa
     6661 agactagaaa ataggtgggc tagtgatctg aaaagctcta gcccaatttt gtaaaagaag
     6721 ggagaaggag aatggttaaa gaacgtaatt taactcgctg gatatttgtt ttgccagcta
     6781 tgattatcgt aggattactc tttgtttatc cgtttttctc gagtattttt tatagcttta
     6841 ccaataagca tttgattatg cctaattata aatttgttgg tttggctaac tataaagctg
     6901 tgctatcaga tcccaacttc tttaatgcgt tctttaattc aattaagtgg accgttttct
     6961 cattagttgg tcaagtttta gtagggtttg tgttggcttt agctcttcac agagtacgcc
     7021 acttcaagaa attatatagg accttattga ttgttccttg ggcatttcct accatcgtta
     7081 ttgccttttc ttggcagtgg attctaaacg gggtttatgg ctacttacct aatctaatcg
     7141 taaaattagg tttaatggaa catacacctg catttttgac agatagtaca tgggcattcc
     7201 tatgtttggt gtttatcaac atttggtttg gagcaccaat gattatggtt aatgtgcttt
     7261 cagctttgca aacagtacca gaagaacaat ttgaggctgc taagatagat ggtgcttcaa
     7321 gttggcaggt gttcaagttt atcgtctttc cacatattaa agtggttgta ggacttctag
     7381 ttgttttgag aactgtatgg atctttaata actttgacat tatctacctc attactggtg
     7441 gtggaccagc caatgctaca acgacgcttc caatttttgc ttacaacctg ggctggggaa
     7501 ctaaattgtt gggtcgtgct tcagcagtta cagtattgct ctttatcttc ttggtggcga
     7561 tttgctttat ctactttgct atcatcagta agtgggaaaa ggagggtaga aaataatgaa
     7621 gaagaaatcc agtatttatt tagatattct ctcacatgta cttttagttg gtgcgaccat
     7681 cgttgcagtt ttcccattgg tatggattat catatcttct gtcaaaggga aaggggaatt
     7741 aactcagtat ccaacacgat tttggcctga acagtttaca ttagattatt tcactcatgt
     7801 tatcaacgat ttgcacttca ttgataacat tcgaaacagt ttaatcattg ccttggctac
     7861 aacccttatt gcgattatta tttctgctat ggcagcctat ggtattgttc gattctttcc
     7921 taaattggga gcaatcatgt cgagactact cgtcattacc tacattttcc caccaatttt
     7981 gttagcaatt ccctattcaa ttgccattgc taaagttggg ttaacaaata gtttatttgg
     8041 cttgatgatg gtttatctat cttttagtgt tccatatgca gtttggctct tagttggatt
     8101 tttccaaaca gttccaattg gaattgaaga agcggctaga attgatggtg caaataaatt
     8161 tgttacgttt tataaagttg tgctaccgat tgtagcacca ggtattgtag caacagctat
     8221 ttatacattt atcaatgctt ggaatgaatt cctgtatgcc ttgattttga ttaacaatac
     8281 aggaaagatg acagtagcag tagcccttcg ttcacttaat ggttcagaaa tactagactg
     8341 gggagatatg atggcagcgt ctgttattgt agttcttcca tcaattattt tcttctctat
     8401 catccaaaat aagattgcaa gtggattatc agaaggatct gtgaagtaga cgaaagaagg
     8461 aaaaaaatga ataaaagagg tctttattca aaactaggaa tttctgttgt aggcattagt
     8521 cttttaatgg gagtccccac tttgattcat gcgaatgaat taaactatgg tcaactgtcc
     8581 atatctccta tttttcaagg aggctcatat caactgaaca ataagagtat agatatcagc
     8641 cctttgttat tagataaatt gtctggagag agtcagacag tagtaatgaa atttaaagca
     8701 gatgaaccaa actctcttca agctttgttt ggcctatcta atagtaaagc aggctttaaa
     8761 aataattact tttcaatttt catgagagat tctggtgaga taggtgtaga aataagagac
     8821 gcccaagagg gaataaatta tttattttcc agaccagctt cattatgggg aaaacataaa
     8881 ggacaggcag ttgaaaatac actagtattt gtatctgatt ctaaagataa aacatacaca
     8941 atgtatgtta atggaataga agtgttctct gaaacagttg atacattttt gccaatttca
     9001 aatataaatg gtatagataa ggcaacacta ggagctgtta atcgtgaagg taaggaacat
     9061 tacctcgcaa aaggaagtat tgatgaaatc agtctattta acaaagcaat tagtgatcag
     9121 gaagtttcaa ctattccctt gtcaaatcca tttcagttaa ttttccaatc aggagattct
     9181 actcaagcta actattttag aataccgaca ctatatacat taagtagtgg aagagttcta
     9241 tcaagtattg atgcacgtta tggtgggact catgattcta aaagtaagat taatattgcc
     9301 acttcttata gtgatgataa tgggaaaacg tggagtgagc caatttttgc tatgaagttt
     9361 aatgactatg aggagcagtt agtttactgg ccacgagata ataaattaaa gaatagtcaa
     9421 attagtggaa gtgcttcatt catagattca tccattgttg aagataaaaa atctgggaaa
     9481 acgatattac tagctgatgt tatgcctgcg ggtattggaa ataataatgc aaataaagcc
     9541 gactcaggtt ttaaagaaat aaatggttat tattatttaa aactaaagaa gaatggagat
     9601 aacgatttcc gttatacagt tagagaaaat ggtgtcgttt atgatgaaac aactaataaa
     9661 cctacaaatt atactataaa tgataagtat gaagttttgg agggaggaaa gtctttaaca
     9721 gtcgaacaat attcggttga ttttgatagt ggctctttaa gagaaaaaca taatggaaaa
     9781 caggtcccta tgaatgtttt ctacaaagat tcgttattta aagtgactcc tactaattat
     9841 atagcaatga caactagtca gaatagagga gagagttggg aacaatttaa gttgttgcct
     9901 ccgttcttag gagaaaaaca taatggaact tacttatgtc ccggacaagg tttagcatta
     9961 aaatcaagta acagattgat ttttgcaaca tatactagtg gagaactaac ctatctcatt
    10021 tcggatgata gtggtcaaac atggaagaaa tcctcagctt caattccgtt taaaaatgca
    10081 acagcagaag cacaaatggt tgaactgaga gatggtgtga ttagaacatt ctttagaacc
    10141 actacaggta agatagctta tatgactagt agagattctg gagaaacatg gtcggaagtt
    10201 tcgtatattg atggaatcca acaaacttca tatggcacac aagtatctgc aattaaatac
    10261 tctcaattaa ttgatggaaa agaagcagtc attttgagta caccaaattc tagaagtggc
    10321 cgtaagggag gtcaattagt tgtcggttta gtcaataaag aagatgatag tattgattgg
    10381 aaataccact atgatattga tttgccttcg tatggttatg cctattctgc gattacagaa
    10441 ttgccaaatc atcacatagg tgtactgttt gaaaaatatg attcgtggtc gagaaatgaa
    10501 ttgcatttaa gcaatgtagt tcagtatata gatttggaaa ttaatgattt aacaaaataa
    10561 aggagaaaaa acatggttaa atacggtgtt gttggagcag ggtattttgg agctgaattg
    10621 gctcgctaca tgcaaaagaa tgatggagca gagattactc ttctctatga tccagataat
    10681 gcagaggcga ttgcagaaga attgggagca aaagtagcaa gttccttaga tgagttggtt
    10741 tctagcgatg aagtagattg tgttatcgtc gcaactccaa ataatcttca taaggaaccg
    10801 gttattaagg ctgcacagca tggtaaaaat gttttctgtg aaaaaccaat tgcgctttct
    10861 tatcaagatt gtcgcgagat ggtagatgcg tgtaaagaaa acaatgtaac ctttatggca
    10921 ggacatatta tgaatttctt taatggtgtt catcatgcaa aagaactcat taatcaagga
    10981 gttatcggag acgttctata ttgtcataca gctcgtaatg gttgggaaga acaacaaccg
    11041 tcagtgtcat ggaaaaaaat tcgtgaaaaa tcaggtggtc acttgtatca ccacatccat
    11101 gaattggatt gcgttcaatt ccttatgggg ggcatgcctg aaactgtaac catgacaggt
    11161 ggaaatgtgg cccatgaagg tgaacatttc ggtgatgaag atgatatgat ttttgtcaat
    11221 atggaatttt ctaataagcg ttttgccttg ttagaatggg gttcagctta tcgttggggt
    11281 gaacattatg tcttaatcca aggaagcaaa ggtgccatcc gcttagactt attcaactgt
    11341 aaaggaactc ttaagctaga tgggcaagaa agctatttct tgattcacga atcgcaagaa
    11401 gaagatgatg atcggactcg tatctatcat agtacagaga tggatggagc aattgcttat
    11461 ggtaaaccag gtaaacgtac tccattatgg ctatcatctg tcattgataa agaaatgcgc
    11521 tatctgcatg agattatgga aggagcccca gtatcagaag aatttgcaaa acttttgaca
    11581 ggtgaagctg ccctagaagc aattgctact gcagatgctt gtacccagtc tatgtttgaa
    11641 gatcgcaaag taaaattgtc agaaattgta aaataaattt tggtattctc ctatttatag
    11701 gtcgacttgc tcctctgaaa gtacttttag aggagctgtt tgactttgct agtttttgaa
    11761 actgaaatct attatactac aaactattga aagcgtttta attttaaggt ataataatct
    11821 catagaaata aagaaaagga ggaaagagga tgccacagat tagcaaagaa gccttgattg
    11881 agcaaatcaa agatggaatc atcgtttctt gtcaggctct tcctcatgaa ccgctttata
    11941 cagaagcggg aggggtgatt cccttgctgg tcaaagcggc tgagcaaggt ggagcagtcg
    12001 gtatccgagc aaacagtgtt cgcgatatca aggaaattaa ggaagtcact aaacttccaa
    12061 tcattgggat tatcaaacgt gattatccac ctcaggaacc cttcatcacg gctactatga
    12121 aagaagttga tgaattggca gaactggaca tcgaggtgat tgctctggat tgtaccaagc
    12181 gtgaacgcta cgatggtttg gaaattcaag agttcattcg tcaggttaag gagaaatatc
    12241 ctaatcagct tttgatggct gatactagta tcttcgaaga agggctagca gctgtagaag
    12301 caggaattga ctttgtcgga acaaccttat caggctacac atcctacagt ccaaaagtag
    12361 acggtccaga ttttgaattg attaagaaac tctgtgatgc cggtgtagat gtcattgcag
    12421 aaggaaaaat tcatacacca gaacaagcca aacaaatcct tgaatatgga gtgcgaggca
    12481 tcgttgttgg tggcgccatt actagaccaa aagagattac agaacgcttc gttgctagtc
    12541 ttaaataaga tgtgagaggg agttttatgt ttaaagtttt acaaaaagtt ggaaaagctt
    12601 ttatgttacc tatagctata cttcctgcag caggtctact tttggggatt ggtggtgcac
    12661 tttcaaaccc aaccacgata gcaacttatc caatactaga caatagtatt tttcaatcaa
    12721 tattccaagt aatgagctct gcaggagagg ttgtattcag taatttgtca ctacttctct
    12781 gtgtgggatt atgtattggc ttagcgaaac gagataaagg aaccgctgcg ttagcaggag
    12841 taactggtta cttagttatg actgcaacga tcaaagcttt ggtaaaactt tttatggcag
    12901 aaggatctgc aattgatact ggagttattg gagcattagt tgtcggaata gttgccgtat
    12961 atttgcacaa ccgatataac aatattcaat taccttccgc tttaggattc tttggaggtt
    13021 cacgcttcgt tcctattgtt acatcgttct cttctatctt gattggcttt gtcttctttg
    13081 ttatttggcc acctttccaa caacttcttg tttctacagg tggatatatt tctcaggcgg
    13141 gtccaattgg aacttttcta tatggatttt taatgagact ttctggagca gtaggcttac
    13201 atcatataat ttaccctatg ttttggtata ctgaacttgg tggtgttgaa actgttgcag
    13261 gacaaacagt ggttggagct caaaaaatat tttttgctca attagccgat ccggcccatt
    13321 ctggattatt tacagaagga acaaggtttt ttgcaggtcg tttctcaaca atgatgttcg
    13381 gtttaccggc tgcctgttta gcgatgtacc atagtgttcc taaaaatcgt cgtaaaaaat
    13441 acgcgggttt gttttttgga gttgctttaa catcttttat taccggtatt acagaaccaa
    13501 ttgaatttat gtttctattc gtcagtccgg ttctatatgt tgttcacgca ttccttgatg
    13561 gtgttagctt ctttattgca gacgtcttaa atatttcaat aggaaacaca ttttcaggag
    13621 gtgtaatcga tttcacttta tttggaattt tgcaggggaa cgctaagacg aattgggttc
    13681 ttcagattcc aattggactt atttggagtg ttttgtatta tattattttt agatggttca
    13741 ttactcaatt caacgttcta acgccaggac gaggagaaga agtagattct aaagaaattt
    13801 ctgaatccgc agattcaact tcaaatactg cagattattt aaaacaggat agcctacaaa
    13861 ttatcagagc cttgggtgga tcaaataata tagaagatgt agatgcttgt gtgacacgtt
    13921 tacgtgtagc tgtaaaagaa gttaatcaag ttgataaagc acttttaaaa caaattggtg
    13981 cagttgatgt cttagaagtg aagggtggca ttcaagcaat atatggagca aaagcaatct
    14041 tatataaaaa tagtattaat gaaattttag gtgtagatga ttaagtactt actgacttaa
    14101 taaaaaacag aggagagtga tggatgagta ggatgaaatg aaatcgcata caagaaataa
    14161 agaactcatt atccaagttg gatacgctta ttacatagga gaatacaaat gaaatttaga
    14221 aaattagctt gtacagtact tgcgggtgct gcggttcttg gtcttgctgc ttgtggcaat
    14281 tctggcggaa gtaaagatgc tgccaaatca ggtggtgacg gtgccaaaac agaaatcact
    14341 tggtgggcat tcccagtatt tacccaagaa aaaactggtg acggtgttgg aacttatgaa
    14401 aaatcaatca tcgaagcgtt tgaaaaagca aacccagata taaaagtgaa attggaaacc
    14461 atcgacttca agtcaggtcc tgaaaaaatc acaacagcca tcgaagcagg aacagctcca
    14521 gacgtactct ttgatgcacc aggacgtatc atccaatacg gtaaaaacgg taaattggct
    14581 gagttgaatg acctcttcac agatgaattt gttaaagatg tcaacaatga aaacatcgta
    14641 caagcaagta aagctggaga caaggcttat atgtatccga ttagttctgc cccattctac
    14701 atggcaatga acaagaaaat gttagaagat gctggagtag caaaccttgt aaaagaaggt
    14761 tggacaactg atgattttga aaaagtattg aaagcactta aagacaaggg ttacacacca
    14821 ggttcattgt tcagttctgg tcaaggggga gaccaaggaa cacgtgcctt tatctctaac
    14881 ctttatagcg gttctgtaac agatgaaaaa gttagcaaat atacaactga tgatcctaaa
    14941 ttcgtcaaag gtcttgaaaa agcaactagc tggattaaag acaatttgat caataatggt
    15001 tcacaatttg acggtggggc agatatccaa aactttgcca atggtcaaac atcttacaca
    15061 atcctttggg caccagctca aaatggtatc caagctaaac ttttagaagc aagtaaggta
    15121 gaagtggtag aagtaccatt cccatcagac gaaggtaagc cagctcttga ataccttgta
    15181 aacgggtttg cagtattcaa caataaagac gacaagaaag tcgctgcatc taagaaattc
    15241 atccagttta tcgcagatga caaggagtgg ggacctaaag acgtagttcg tacaggtgct
    15301 ttcccagtcc gtacttcatt tggaaaactt tatgaagaca aacgcatgga aacaataagc
    15361 ggctggactc aatactactc accatactac aacactattg atggatttgc tgaaatgaga
    15421 acactttggt tcccaatgtt gcaatctgta tcaaatggtg acgaaaaacc agcagatgct
    15481 ttgaaagcct tcactgaaaa agcgaacgaa acaatcaaaa aagctatgaa acaatagtcc
    15541 ttagttattc tataaaaagt agttttttaa agaacctaag agtgtatacc cccttttccc
    15601 tctacacaga tagtgtaaga aaagggggct tttgtttaaa atgtaagaaa ctgtcacgaa
    15661 attaaaatga agttcttaca taagcgaatc ataaaaaatt tcattttgat tttaaaacag
    15721 ttcaagaaag tcaaaaaatt attctatttg aaagagaggt gccgactgtg aaagtcaata
    15781 aaatccgtat gcgggaaaca gtgatttcct acgctttcct agcaccagta ttattcttct
    15841 ttgtcatctt tgtgttggct ccgatggtga tgggcttcat tacaagtttc tttaactact
    15901 caatgactaa atttgagttt gtaggcttgg ataactatat ccgtatgttt aaagatcctg
    15961 tctttacaaa atctctgatt aacacagtta ttttggttat tggatctgta ccagttgttg
    16021 ttctattctc actctttgta gcatctcaga cctatcatca aaatgtcatt gccagatcct
    16081 tctaccgttt cgtcttcttc cttcctgttg taacgggtag tgttgccgtg acagttgttt
    16141 ggaaatggat ttatgaccca ctatcaggga ttctaaactt tgtccttaag tccagccaca
    16201 tcatcagcca aaacatttct tggttgggag ataaaaactg ggcattgatg gcgattatga
    16261 ttattctctt gaccacttca gttggtcagc ccatcatcct ttatatcgct gccatgggga
    16321 atattgacaa ttcactggtt gaagcggcgc gtgttgatgg tgcaactgag tttcaagttt
    16381 tttggaagat taaatggcca agccttcttc caacaactct ttatattgca atcatcacaa
    16441 caattaactc attccagtgt ttcgccttga ttcagctttt gacatctggt ggtccaaact
    16501 actcaacaag taccttgatg tactaccttt acgaaaaagc cttccaattg acagaatacg
    16561 gctatgccaa cacaattggt gtcttcttgg cagtcatgat tgctatcgta agctttgttc
    16621 aatttaaagt acttggaaac gacgtagaat actaaagaaa ggagacagct atgcaatcta
    16681 cagaaaaaaa accattaaca gcctttactg ttatttcaac aatcattttg ctcttgttga
    16741 ctgtgctgtt catctttcca ttctactgga ttttgacagg ggcattcaaa tcacaacctg
    16801 atacaattgt tattcctcct cagtggttcc ctaaaatgcc aaccatggaa aacttccaac
    16861 aactcatggt gcagaaccct gccttgcaat ggatgtggaa ctcagtattt atctcattgg
    16921 taaccatgtt cttagtttgt gcaacctcat ctctagcagg ttatgtattg gctaaaaaac
    16981 gtttctatgg tcaacgcatt ctatttgcta tctttatcgc tgctatggcg cttccaaaac
    17041 aagttgtcct tgtaccattg gtacgtatcg tcaacttcat gggaatccac gatactctct
    17101 gggcagttat cttgcctttg attggatggc cattcggtgt cttcctcatg aaacaattta
    17161 gtgaaaatat tcctacagag ttgcttgaat cagctaaaat cgacggttgt ggtgagattc
    17221 gtaccttctg gagtgtagcc ttcccgattg tgaaaccagg gtttgcagcc cttgcaatct
    17281 ttaccttcat caatacttgg aatgactact tcatgcaatt ggtaatgttg acttcacgta
    17341 acaatttgac catctcactt ggggttgcga ccatgcaggc tgaaatggca accaactatg
    17401 gtttgattat ggcaggagct gcccttgctg ctgttccaat cgtcacagtc ttcctagtct
    17461 tccaaaaatc cttcacacag ggtattacta tgggagcggt caaaggataa tactctgaga
    17521 aaatctcttc aaactacgtc agcgtcacct tgccatactt aagtattgcc tgcggttagc
    17581 ttcctagttt gttcttcaat tttcattgag tataggaaaa tcaatctatc aagatacaga
    17641 agtatatttt atagatttag agaatataga ggttataagt gtctacaaaa tggagggtat
    17701 gcagttactt tatgaagttt tgtcagacac ttataaactt aagaatggtt ttagttaact
    17761 atcagaaacg aaggaaagag tatgattttt gacgatttga aaaacatcac cttttacaaa
    17821 gggattcatc ccaatttaga caaggctatc gactatctct accaacatcg taaagattca
    17881 ttcgaattag gaaagtatga gattgatgga gataaagtct ttctagttgt tcaggaaaat
    17941 gtcctcaatc aagttgagaa taatcaattt gaacaccata agaactatgc agatttgcat
    18001 ttgctggtag aaggacatga atattcgagc tacggttcac gtatcaaaga cgaggcagta
    18061 gcattcgacg aagcgactga cattggcttt gttcattgtc atgaacacta cccactcttg
    18121 ttgggttatc ataattttgc gattttcttc ccaggtgagc cacatcagcc aactggctat
    18181 gcaggtatgg aagaaaaggt tcgaaaatat ctctttaaaa ttttgattga ttaaaaatag
    18241 gatgaattgt ttttttgtaa agctttgaca atactctacc atgaaattga tctttgtgag
    18301 gtatagaaat gagaataaaa tatttaaaaa ttggtatctt ctaagcatgc tgcaagagct
    18361 agtttcttag atggacaggg gattacagtt gatgagatgt cctggataat taatggcatt
    18421 gtgaatgcat tgattggtag atacataaaa ttaggtactt atgcagctaa gtatggtatt
    18481 agtatagcac gctcgatctt aagtagggca gctgcaactg cagcagcaag agtaggatta
    18541 ctgaccaaga tttctggatg gattttacga gtagctgtga atgtagctga tgtatatggt
    18601 aattttgcca acaatattgc tgcagcttgg gatgcatatg ataaaattcc taacaatggt
    18661 cgtataaact tttaaaatgc gagaatgaaa gcactttgta tttttttatt gaatatgtta
    18721 gcttggacag tgcttgcaat gataattcgt ggagggctag atggatttga taggcatact
    18781 tggagtacta ttttaattgc ttcgctgttc ggggtatatg attataagcc catagataaa
    18841 aatagaaaaa agtccaaaag aaaaaagaaa aaatagattt gttcatggta gggacttatg
    18901 aaagctttac tgacaaaaaa gaaaacagtt tacaaagaaa aatgatggag gagcaaacat
    18961 ggcacaaaaa ggagtaagcc ttatcaaggc agcatttgat acagacaact ttctcatgcg
    19021 ttttagtgag aaagtcttgg acatcgtgac agccaatctt ctttttgtcg tctcttgttt
    19081 gcccatcgtg acgattggag tggctaaaat cagcctctac gagaccatgt tcgaagttaa
    19141 gaagagcaga cgggtgcctg tttttaaaat ctatctaaga tctttcaagc aaaatctgaa
    19201 actaggtctt cagctgggtt taatggagtt aggaattgtg tttcttaccc tttcagatct
    19261 ctatcttttc tggggtcaaa cagctctgcc cttccaattg ctgaaagcca tttgtttagg
    19321 tattctgatt tttcttacta tcgtgatgct ggctagttac cctatcgcgg cacgttatga
    19381 cctatcttgg aaagaaattc ttcaaaaagg attgatgttg gctagtttta actttccttg
    19441 gttcttcctc atgttagcca ttcttgtcct cattgtgatg gttctttatc tgtccgcctt
    19501 cagtctactc ttaggtggct cagtcttctt actttttggg tttggactat tggtctttat
    19561 ccagactgga ttgatggaga aaattttcgc aaaataccaa taggagcctt atttctgaaa
    19621 ctactttcaa acgctccaaa cgctattcta taagcgagaa actaaaatct aagtgtctat
    19681 aagatattga aagccttttc ggtaaagtgt atactaaaga agtaaagaaa aatctgcttt
    19741 agcagaaaat aaaaataata ggagaaaatc tatgtcagat ttgaaaaaat acgaaggtgt
    19801 cattccagcc ttctacgcat gttatgatga tcaaggagaa gtaagcccag aacgtacgcg
    19861 tgccttggtt caatacttca ttgataaagg tgttcaaggt ctttatgtca atggttcttc
    19921 tggtgaatgt atctaccaaa gtgttgaaga ccgcaagtta atcttggaag aagtcatggc
    19981 ggtagccaaa ggtaaattga ccattattgc ccatgttgct tgcaataata ctaaagatag
    20041 tatggaactt gctcgccatg ctgaaagctt gggagtagat gctattgcaa cgattccacc
    20101 aatttatttc cgcttgccag aatactcagt tgccaaatac tggaacgata tcagttctgc
    20161 agctccaaac acagactacg tgatttacaa cattcctcaa ttggcagggg ttgctttgac
    20221 tccaagcctt tacacagaaa tgttgaaaaa tcctcgtgtt atcggtgtga agaactcttc
    20281 tatgccagtt caagatatcc aaacctttgt cagccttggt ggggaagacc atatcgtctt
    20341 taatggtcct gatgagcagt tcctaggagg acgcctcatg ggtgctaggg ctggtatcgg
    20401 tggtacttat ggtgctatgc cagaactctt cttgaaactc aatcagttga ttgcggataa
    20461 ggacctagaa acagcgcgtg aattgcagta tgctatcaac gcaatcattg gtaaactcac
    20521 ttctgctcat ggaaatatgt acggtgtcat taaagaagtc ttgaaaatca atgaaggctt
    20581 gaatattgga tctgttcgtt caccattgac accagtgact gaagaagatc gtccagttgt
    20641 agaagcggct gctgccttga ttcgtgaaac caaggagcgc ttcctctaat ataaaaggag
    20701 gtatttatga catactacgt tgcaattgat atcggtggaa ccaacatcaa gtatggtttg
    20761 gttgatcaag aggggcaact tcttgaatcg catgaaatgc caactgaggc gcataagggt
    20821 ggacctcata tcttacaaaa gaccaaagat atcgtagcta gttatttaga aaaaggccca
    20881 gtagcaggtg ttgccatatc ttctgctggg atggtggatc cggataaggg tgagattttc
    20941 tatgctgggc ctcaaatccc taactacgca ggcacccagt tcaaaaagga aatcgaagaa
    21001 agctttacta ttccttgtga gattgaaaat gatgtcaact gtgcaggtct tgctgaggca
    21061 gtatctggtt caggcaaggg agcaagtgtg acactttgct tgaccattgg aaccggtatc
    21121 ggtggttgct tgattatgga taggaaagtc ttccatggtt ttagcaattc agcctgtgaa
    21181 gtcgggtata tgcatatgca ggatggagct tttcaggatc tcgcttctac aacagcttta
    21241 gtgaaatatg tagctgaagc ccatggagaa gatgttgatc agtggaatgg ccgacgtatc
    21301 tttaaggaag ctactgaagg aaacaaaatc tgcatggaag gtattgaccg tatggttgac
    21361 tatctaggaa aaggtctggc aaatatttgt tatgtggcca atccagaagt ggttattctt
    21421 ggtggtggta tcatggggca agaggctatc ctcaaaccta agatccgcac agccttgaaa
    21481 gaggcattgg taccaagttt agcagaaaaa acacgattag aatttgccca tcaccaaaat
    21541 acagcaggga tgttgggtgc atattatcat tttaagacaa aacaatccta gtttggctca
    21601 gccaaactag gattttctta cacgtttttg tctacgatag ccgttgagtt ttttattttc
    21661 ccagtagcta ttaaagattt tttccttgct ttcgcgattg atttccaaaa agtaggcata
    21721 aatcaaatcg ataaagaaga gcataggaag ttgagcggat attcgttgga tgtaggaggg
    21781 ttggctgtgg gtggctacaa gaacagtctc tgtataggtc tggctatctt tattgggaac
    21841 acttgtaaag agtacagtct ttgcccccat ctccttggca tctaatagac tatctaaaat
    21901 agaaggagtt gagcctgaaa gtgagaaacc cagtactaga caattttcat ccatgatgct
    21961 ggttgtccag gcaaagccgt cttggtctgt caaagcttcg cagaccacac ctagtcgcat
    22021 aaaacgtaat ttcatttcac gggcgacgag gccagaactc cctgttccaa agaagtagat
    22081 acgctcagca tcttcgatta gctgggcaat tcgctctagt tggatttcgt caatcaagtc
    22141 ttgtgtttgt tccctcatgt tgctataact tctgaggact cgtttggtca gtggactgtg
    22201 cttggaaact tggttggctt gattttctgc ctgatgttgg tattggaaaa taaattctcg
    22261 gtagccagta aagccacact ttttagcaaa gcgggtcaaa gcagcttgag aaatatgtaa
    22321 tttttgggtg acttgttgag aagataaatc atctgtaatc gtttcagctt gcaaaaaata
    22381 gcgagcgatt tcttgctcta ggtctgtcat ttcttcaaaa tgtgaatcaa tgatagttgc
    22441 gatatctggt ttgtccatag ggaaagctcc tttacatgag tcatactgga agactagatc
    22501 agggaatagt cacacttcat tataacacat aatataagga tagataaata aaaacgcatc
    22561 tctgttttaa aaacgaaaaa atcgaaaaag cttctctctt ttccataatt ttctactcaa
    22621 attgtggtac aattaagagt aagattttaa gttagaaatg agactgattt gtatgagaaa
    22681 atttaacagc cattcgattc cgattcggct taatttattg ttttcaatcg tcattttact
    22741 ctttatggcc attattggtc gtttgttgta tatgcaggtt ttgaacaagg atttttacga
    22801 aaaaaagcta gcctcagcta gtcagaccaa gattacaagc agttcagccc gtggggaaat
    22861 ttatgatgct agtggaaaac ctttggtaga aaatacgtta aagcaggttg tttcctttac
    22921 gcgtagcaat aaaatgacgg ctacagactt aaaagaaaca gctaaaaagt tactgactta
    22981 tgtgagcatc agttctccaa atttgacaga acgccagctg gcggattact atttggctga
    23041 tcctgaaatc tataaaaaaa cagtggaagc tctcccaagc gagaaacgct tggattcaga
    23101 tggcaatcgt ctatccgaat cagaactgta taacaatgcg gtcgatagtg tacaaacgag
    23161 tcaactaaac tatacagagg atgaaaagaa agaaatctat ctttttagtc agttaaatgc
    23221 tgttggaaac tttgcgacag gaaccattgc gacagatcct ctaaatgatt ctcaggtggc
    23281 tgttattgcc tctatttcaa aggagatgcc tggcattagt atttctactt cttgggatag
    23341 aaaggttttg gaaacttccc tttcttctat agttgggagt gtatccagtg aaaaagctgg
    23401 tctcccagcg gaagaagcag aagcctatct taaaaaaggc tattctctaa atgatcgtgt
    23461 aggaacctcc tatttggaaa agcaatatga agagacctta caaggaaaac gctcggtaaa
    23521 agaaatccat ctggataaat atggcaatat ggaaagcgtg gatacaattg aggaaggtag
    23581 taagggaaac aatatcaaac tgaccattga tttggctttc caagatagcg tggatgcttt
    23641 actgaaaagt tatttcaatt ccgagctaga aaatggtgga gccaagtatt ctgaaggtgt
    23701 ctatgcagtc gcccttaacc caaaaacagg tgcggttttg tctatgtcag ggattaaaca
    23761 tgacttgaaa acgggagagt tgacgcctga ttccttggga acggtaacca atgtctttgt
    23821 gccgggttct gttgtcaagg cggcgaccat cagctctggt tgggagaatg gagtcttatc
    23881 agggaatcag accttgacag accaaccgat tgtcttccaa ggttcagctc cgattaattc
    23941 ttggtacact caggcttacg gttcattccc gattacagct gtggaagcct tggagtattc
    24001 ttctaatgcc tatatggttc aaacggcttt gggcattatg ggtcagacct atcaacccaa
    24061 tatgtttgtt ctaactaaca atttagaatc cgccatgggg aaacttcgct cgacatttgc
    24121 ggaatatggt cttggagcct caacaggcat tgaccttcca gatgagtcaa ctggttttat
    24181 accaaaagag tataattttg ctaattacat taccaatgcc tttggtcagt ttgataacta
    24241 cactcctatg caattggccc agtacgttgg aaccattgcc aacaacggtg ttcggattgc
    24301 acctcacatt gtcgagggga tttatggaaa caatgaacaa ggcggcttag ggaacttaat
    24361 ccaatctgtt gaatccaagg aaatgaataa aattaatatt tctgagtctg atgtttccat
    24421 cctccaacaa ggcttttatc aagtgtcaca tggtggtagt gctttgacaa ccggtcgtgc
    24481 cttttcaaat ggcgcaagcg tatcgattag tggtaaaaca ggtactgccg aaagttatgt
    24541 tgagggtggt caagaagcta acaatactaa tgctgtggcc tatgcaccat cagataatcc
    24601 tcaaatcgct gtagctgttg tcttccctca taacaccaac cttacaaatg gtgtcggacc
    24661 ttccattgcg cgcgatatta tcaacctcta taaccaacat catccaatga attagaaagg
    24721 aacatatgct ttatccaaca cctattgcta agctaattga cagttattct aagttaccgg
    24781 gtatcgggat taagacggct acacgtctgg ccttctatac tattggaatg tctgatgacg
    24841 atgtcaatga atttgctaaa aatctccttt ctgctaagag agagctgacc tactgttcca
    24901 tctgcggtcg cctgactgat gacgatcctt gctctatctg taccgatccg actcgtgacc
    24961 agacaacgat tttagttctc gaagatagtc gcgatgtggc agccatggag aatatccaag
    25021 aataccatgg actctatcat gtcttgcatg gactcatttc tcccatgaat ggtattagtc
    25081 cagatgatat caatctcaag agcctcatga ctcgtcttat ggatagtgaa gtttcagagg
    25141 taatcgtagc aacaaatgct acagcagatg gtgaagcgac atccatgtat ctttcacgtt
    25201 tgctcaagcc agctggtatc aaggttacgc gtctagcacg aggtctcgct gtcggagcgg
    25261 acattgagta tgcggatgaa gtgacgctct tacgagccat tgaaaatcga acagagttgt
    25321 aagtgtaggc aaatttacga actccattca tttataaaaa atcaaagagg ctgaaaatcg
    25381 ttcctatcgg cctctttttg tatagtgtga tgagtaggat caggttcaag ttttaaaaaa
    25441 ccaagcaaat atgatatact aaagagcgag tattctagta gaattaggac gaataatatg
    25501 aaacaaacga ttattctttt atatggtgga cggagtgcgg aacgcgaagt ctctgtcctt
    25561 tcagctgaga gtgtcatgcg tgcggtcgat tacgaccgtt tcacagtcaa gactttcttt
    25621 atcagtcagt caggtgactt tatcaaaaca caggaattta gtcatgatcc ggggcaagaa
    25681 gaccgtctca tgaccaatga aaccattgat tgggataaga aagttgcacc aagtgctatc
    25741 tacgaagaag gtgcagtggt ctttccagtc cttcacgggc caatgggaga agatggctct
    25801 gttcaaggat tcttggaagt tttgaaaatg ccttacgttg gttgcaacat tttgtcatca
    25861 agtcttgcca tggataaaat cacgactaag cgtgttctgg aatctgctgg tattgcccaa
    25921 gttccttatg tggctatcgt tgaaggcgat gatgtgactg ctaaaatcgc tgaagtggaa
    25981 gaaaaattgg cttatccagt cttcactaag ccgtcaaaca tggggtctag tgtcggtatt
    26041 tctaagtctg aaaaccaaga agaactccgt caagccttag aacttgcctt ccgatatgat
    26101 agccgtgtct tggttgagca aggagtgaat gcccgtgaaa ttgaggttgg cctcttgggt
    26161 aactacgatg tcaagagcac gctaccagga gaagttgtca aggatgttgc cttttatgac
    26221 tacgatgcca agtatattga taacaagatt actatggata ttcctgccaa aatcagtgat
    26281 gatgtggtgg ctgtcatgcg tcaaaatgca gaaacagcct tccgtgccat tggtggcctt
    26341 ggtctatctc gttgcgattt cttctataca gataagggag agatttttct caacgagctc
    26401 aataccatgc caggtttcac ccagtggtct atgtacccac tactttggga caatatgggg
    26461 atcagctacc cagaactaat cgagcgtttg gttgaccttg ccaaggaaag ttttgacaag
    26521 cgcgaagcgc atttgatata aaatgaaaga gagggtagaa gccagaacca tcactgcacg
    26581 gtgactagag ttctcggact tcagcccttt ttaaaggagt agaaatgaaa ttaacaatcc
    26641 atgaaattgc ccaagttgtt ggagccaaaa atgatatcag tatctttgag gacacccagt
    26701 tagaaaaagc tgagtttgat agtcgtttga ttggaactgg agatttattt gtgccactta
    26761 aaggtgcgcg tgatggccat gactttattg aaacagcctt tgaaaatggt gcagcagtaa
    26821 ccttgtctga gaaagaggtc tcaaatcatc cttacattct agtagatgat gttttgacag
    26881 cctttcaatc cctagcatcc tactatcttg aaaaaacgac tgttgatgtc tttgctgtta
    26941 caggttcaaa tggcaagaca acgactaagg atatgttggc gcatttactg tcaacaagat
    27001 acaagaccta caaaacacaa ggcaattaca ataacgagat tggccttcct tacacagttc
    27061 ttcatatgcc tgaagggaca gaaaagttgg tcttggagat ggggcaggat cacttgggag
    27121 atattcatct cttgtctgaa ttggctcgtc caaaaacagc catcgtgacc ttggttggag
    27181 aagcccattt ggcctttttc aaagaccgtt cagagattgc taagggaaaa atgcaaattg
    27241 cagacggaat ggcttcaggt tccttgcttt tagcgccggc tgaccctatc gtagaggact
    27301 atttgccaac tgataaaaag gtggttcgtt ttggtcaagg agcagagctg gaaattactg
    27361 acttggttga gcgcaaagat agtctgacct tcaaggccaa tttcttagag caagtccttg
    27421 atttgccagt gactggcaag tacaatgcga caaatgctat gattgcgtcc tatgttgccc
    27481 tacaagaagg agtttcagag gagcaaattc atcaggcctt ccaaggtctt gaattgacgc
    27541 gtaatcgtac tgagtggaag aaagcagcca atggagcaga tatcctgtca gacgtatata
    27601 atgccaatcc aactgctatg aagctgattt tagagacttt ctctgccatt ccagccaatg
    27661 aaggtggcaa gaaaattgca gtgttggcgg atatgaagga gcttggtgac cagtctattc
    27721 aactccataa ccagatgatt ttgagccttt ctccagatgt gcttgatatc gttattttct
    27781 atggagaaga cattgctgaa ttagcccaat tggctagtca aatgttccca atcggacacg
    27841 tttattactt caagaaaaca gaagaccaag accaatttga agacctagtt aagcaggtca
    27901 aagaaagcct tggggctcat gaccaaatcc tgctcaaagg ctctaactct atgaatctag
    27961 ccaagttggt agaaagttta gaaaatgaag acaagtgatt ttgtcaagta tttgcaaaga
    28021 atgattgctc ttacagatac tggcttaacc tttacaaaag atccgtttga ccgtgagcgc
    28081 tacgaagact tgcgagacct tttatctgaa atgttgaatc aagcatcaga ccttgattcc
    28141 gaagaagtgg cagaagtctt gaagccaact tctgcttatg cgactccgtt aatggacgtc
    28201 cgtgcttgga ttgttgagga cgaaaagatt tgtctggtta ggggacaagg agaggatagt
    28261 tgggctttgc caggtggctt tggtgaagtc ggctattctc caactgaaaa tattctcaag
    28321 gaaattgaag aagaaaccgg ttttaaagcc aaagttgaaa gactgctagc tgtttttgat
    28381 accaatcgtt tccaactaca gagcaaacaa tatgcaaagt ttgtttttga atgtaagctt
    28441 ctcgatggac aattccaaga aaatcaagaa atcgctgacc ttcaattttt tgcaattgac
    28501 caactgccga atttatctga aaaacgcatt accaaggagc aaatcgagat tctttggcag
    28561 gtttatcaag gtcagaggga gcaatatctt gactaagaag atgattatcg tatttctaaa
    28621 tttatttttc ttaagtagca tggtataata aaatgcagga aaattttgaa tcatgaggaa
    28681 gactagatga atttatggga tattttcttt acgactcagg caaccgagcc gcccaaattt
    28741 gacctttttt ggtatgttag cctatttacg ctcttagcct taacctttta tacagcccat
    28801 cgctatcgtg aaaagaaggt ttaccaacga tttttccaaa tcttgcagac tgttcagtta
    28861 atccttcttt atggttggta ctgggtcaat catatgccac tgtcagaaag cctacccttt
    28921 taccattgcc gtatggctat gtttgtggta ctcttgcttc ctggtcagtc caaatataaa
    28981 caatactttg cattattggg aacatttggg acattagcag cctttgttta tccagtgcca
    29041 gatgcttacc cttttccaca tatcaccatt ctatccttta tctttggtca tttagcactc
    29101 ttggggaact ctctagttta tctattgaga cagtataatg cgcgattgct ggatgtgaag
    29161 ggaatttttc tcatgacctt tgccctaaat gccttgattt ttgtggtcaa tttggtgaca
    29221 ggtggcgatt acggattttt gacaaaaccg ccattggttg gggatcatgg tctagtagct
    29281 aattatttac ttgtttcaat tgtgctggta gctactatca gtttgactaa gaaaatctta
    29341 gaattctttt tagctcaaga agcagaaaaa atgattgcaa aggaagctta acacagagct
    29401 ttcttttttg ctcttagaga gtttttacaa gcagcttata aaataagaat ttctgaatag
    29461 acaaactcaa aaaatggctg ggaaatttag gaaaaaagca agcacgatta aattttttgt
    29521 gttataatat tttgtgaata gctatgccta tgtttagcta tggaataata cgaagtgcga
    29581 aacttggaag atagagagga agcgatgtaa tggctagaga aggctttttt acaggtctag
    29641 atattggaac aagctctgtc aaggtgcttg tggccgagca gagaaatggt gaattaaatg
    29701 taattggcgt gagtaatgcc aaaagtaaag gtgtaaagga tggaattatt gttgatattg
    29761 atgcagcagc aactgctatc aagtcagcca tttcccaagc ggaagaaaag gcaggcattt
    29821 cgattaaatc agtgaatgtc ggcttgcctg gtaatctttt gcaggtagaa ccaactcagg
    29881 ggatgattcc agtaacatct gatactaagg aaattacgga tcaagatgtt gaaaatgttg
    29941 tcaaatcagc tttgacaaag agtatgacac ctgaccgtga agtcattacc tttattcctg
    30001 aagaatttat tgtggatggt ttccaaggga ttcgtgaccc acgtggcatg atgggggttc
    30061 gccttgaaat gcgtggtttg ctttatacag gacctcgtac tatcttgcac aatttgcgta
    30121 agacggttga gcgtgcaggt gttcaggttg aaaatgttat catttcacca ctagcaatgg
    30181 ttcagtctgt tttgaacgaa ggggaacgtg aatttggtgc tacagtgatt gatatggggg
    30241 caggtcaaac gactgtcgct acaatccgta atcaagaact ccagttcaca catattctcc
    30301 aagaaggtgg agattatgta actaaagata tctccaaggt tttgaaaacc tctcgcaaat
    30361 tagcggaagg cttgaaactg aattacgggg aagcctatcc gcctcttgca agcaaagaaa
    30421 ccttccaagt agaggttatt ggagaagtag aagcagtcga agtgacggaa gcctacttgt
    30481 cagaaattat ttctgcacga atcaagcaca tccttgaaca aatcaagcaa gaattagata
    30541 gaaggcgtct attggacctc cctggtggta ttgtcttaat cggtgggaat gccattttac
    30601 caggtatggt tgagcttgct caggaagtct ttggcgtccg tgtcaagctt tatgttccaa
    30661 atcaagttgg tatccgtaat ccagcctttg cgcatgtgat tagtttatca gaatttgcgg
    30721 gtcaattaac agaagttaat cttttggctc agggagcgat aaaaggtgag aatgacttaa
    30781 gtcatcagcc aattagtttt ggtgggatgc tgcaaaaaac agctcagttt gtacaatcaa
    30841 cgcctgttca accagctcct gctccagaag tagagccggt ggcgcctaca gaaccaatgg
    30901 cggatttcca acaagcttca caaaataaac cgaaattagc agatcgtttc cgtggattga
    30961 tcggaagcat gtttgacgaa taaagaggaa aaataaatta tgacattttc atttgataca
    31021 gctgctgctc aaggggcagt gattaaagta attggtgtcg gtggaggtgg tggcaatgcc
    31081 atcaaccgta tggtcgacga aggtgttaca ggcgtagaat ttatcgcagc aaacacagat
    31141 gtacaagcat tgagtagtac aaaagctgag actgttattc agttgggacc taaattgact
    31201 cgtggtttgg gtgcaggagg tcaacctgag gttggtcgta aagccgctga agaaagcgaa
    31261 gaaacactga cggaagctat tagtggtgcc gatatggtct tcatcactgc tggtatggga
    31321 ggaggctctg gaactggagc tgctcctgtt attgctcgta tcgccaaaga tttaggtgcg
    31381 cttacagttg gtgttgtaac acgtcccttt ggttttgaag gaagtaagcg tggacaattt
    31441 gctgtagaag gaatcaatca acttcgtgag catgtagaca ctctattgat tatctcaaac
    31501 aacaatttgc ttgaaattgt tgataagaaa acaccgcttt tggaggctct tagcgaagcg
    31561 gataacgttc ttcgtcaagg tgttcaaggg attaccgatt tgattaccaa tccaggattg
    31621 attaaccttg actttgccga tgtgaaaacg gtaatggcaa acaaagggaa tgctcttatg
    31681 ggtattggta tcggtagtgg agaagaacgt gtggtagaag cggcacgtaa ggcaatctat
    31741 tcaccacttc ttgaaacaac tattgacggt gctgaggatg ttatcgtcaa cgttactggt
    31801 ggtcttgact taaccttgat tgaggcagaa gaggcttcac aaattgtgaa ccaggcagca
    31861 ggtcaaggag tgaacatctg gctcggtact tcaattgatg aaagtatgcg tgatgaaatt
    31921 cgtgtaacag ttgttgcaac gggtgttcgt caagaccgcg tagaaaaggt tgtggctcca
    31981 caagctagat ctgctactaa ctaccgtgag acagtgaaac cagctcattc acatggcttt
    32041 gatcgtcatt ttgatatggc agaaacagtt gaattgccaa aacaaaatcc acgtcgtttg
    32101 gaaccaactc aggcatctgc ttttggtgat tgggatcttc gccgtgaatc gattgttcgt
    32161 acaacagatt cagtcgtttc tccagtcgag cgctttgaag ccccaatttc acaagatgaa
    32221 gatgaattgg atacacctcc atttttcaaa aatcgttaag taaatgaatg taaaagaaaa
    32281 tacagaactt gtttttcgag aagttgcaga ggctagtctg agtgctcatc gagagagtgg
    32341 ttcggtctct gtcattgcag ttaccaagta tgtagatgta ccgacagcgg aagccttgct
    32401 tccgctaggt gtccatcata tcggtgaaaa tcgtgtagat aagtttctgg aaaaatatga
    32461 agctttaaaa gatcgagatg tgacttggca tttgattggt accttgcaaa gacgtaaggt
    32521 gaaagatgtc attcaatacg ttgattattt ccatgcattg gactcagtaa agctagcagg
    32581 ggaaattcaa aaaagaagtg accgagtcat caagtgtttc cttcaagtaa atatttctaa
    32641 agaagaaagc aaacacggtt tttcgagaga ggaactgctg gaaatcttgc cagagttagc
    32701 cagactagat aagattgaat atgttggttt aatgacgatg gcaccttttg aggctagcag
    32761 tgagcagttg aaagagattt tcaaggcggc ccaagattta caaagagaaa ttcaagagaa
    32821 acaaattcca actatgccta tgaccgagtt aagtatggga atgagtcgtg attataaaga
    32881 agcaattcaa ttcggttcca cttttgttcg tataggtaca tcatttttta agtaggagag
    32941 aaccatgtct ttaaaagata gattcgatag atttatagat tattttacgg aggatgagga
    33001 ttcaagtctc ccttatgaaa aaagagatga gcctgtgttt acttcagtaa attcttcaca
    33061 ggaaccggct ctcccaatga atcaaccttc acagtcggct ggtacaaaag agaacaatat
    33121 caccagactt catgcaagac aacaggaatt ggcaaatcag agtcagcgtg caacggataa
    33181 ggtcattata gatgttcgtt atcctagaaa atatgaggat gcaacagaaa ttgttgattt
    33241 attggcagga aacgaaagta tcttgattga ttttcagtat atgacagagg tgcaggctcg
    33301 tcgttgtttg gactatttgg atggagcttg tcatgtttta gctggaaatt tgaaaaaggt
    33361 agcttctacc atgtatttgt tgacaccagt gaacgttatt gtaaatgttg aagatatccg
    33421 tttaccagat gaagatcaac agggtgagtt cggttttgat atgaagcgaa atagagtacg
    33481 ataatgattt ttttaattcg tatgatttat aatgcagtgg atatttactc cctgattttg
    33541 gtaaccttcg ctgtcatgtc ttggtttcca ggtgcctacg aatccagttt aggtcgttgg
    33601 attgtagcgt tggtgaaacc agtgcttgct cccttgcaac gcctgccttt acagatagcg
    33661 ggtcttgatt tatctgtttg ggtcgcgatt gttttggttc gatttttagg agaaaaccta
    33721 gtgcgttttc tggcgatgat aggatgaata aagggattta tcagcatttc tccatagaag
    33781 atcgtccatt tcttgacaag ggaatggaat ggataaagaa ggtagaagat agctatgctc
    33841 cttttttaac tccttttatc aatcctcatc aggagaagct attaaagatt ttggccaaaa
    33901 catatggtct tgcttgtagc agtagtgggg aattcgtctc gagtgagtat gttcgagttt
    33961 tattataccc agattatttc caaccagagt tttcagattt tgaaatatct ctccaggaaa
    34021 ttgtgtattc caataaattt gaacatttaa cgcatgctaa gattttaggg acagtcatca
    34081 atcaattagg gattgaacgg aaactttttg gagatatcct agtagatgaa gaacgggcgc
    34141 agattatgat taatcagcag tttcttcttc tctttcaaga tggactaaag aaaattggtc
    34201 gtatacctgt ttcgctggag gaacgtcctt tcaccgagaa aatagataag ctagaacagt
    34261 atcgagaact ggatttatct gtgtctagtt ttcgattaga tgttctttta tcaaatgttt
    34321 tgaaactatc taggaatcaa gcaaaccagt tgattgaaaa gaaacttgtc caagtaaatt
    34381 atcatgtggt agacaaatca gattacactg ttcaagttgg agacttgatt agtgtgagaa
    34441 aatttggtcg cttgagatta cttcaagata agggacaaac gaaaaaagag aagaaaaaaa
    34501 taaccgtcca gttattatta agtaagtgag gaatagaatg ccaattacat cattagaaat
    34561 aaaggacaag acttttggaa ctcgattcag aggttttgat ccagaagaag tcgatgaatt
    34621 tttagatatt gtggttcgtg attacgaaga tcttgtgcgt gcgaatcatg ataaaaattt
    34681 gcgtattaag agtttagaag agcgtttgtc ttactttgat gaaataaaag attcattgag
    34741 ccagtctgta ttgattgccc aggatacagc tgagcgagtg aaacaggcgg cgcatgaacg
    34801 ttcaaacaat atcattcatc aagcagagca agatgcgcaa cgcttgttgg aagaagctaa
    34861 atataaggca aacgagattc ttcgtcaagc aactgataat gctaagaaag tcgctgttga
    34921 aacagaagaa ttgaagaaca agagccgtgt cttccaccaa cgtctcaaat ctacaattga
    34981 gagtcagttg gctattgttg aatcttcaga ttgggaagat attctccgtc caacagctac
    35041 ttatcttcaa accagtgatg aagcctttaa agaagtggtt agcgaagtac ttggagaacc
    35101 gattccagct ccaattgaag aagaaccaat tgatatgaca cgtcagttct ctcaagcaga
    35161 aatggaagaa ttacaagctc gtattgaggt agccgataaa gaattgtctg aatttgaagc
    35221 tcagattaaa caggaagtgg aaactccaac tcctgtagtg agtcctcaag ttgaagaaga
    35281 gcctctgctc atccagttgg cccaatgtat gaagaaccag aagtagctcc agtgcatccg
    35341 acaggtccaa caccagctac agaaactgtt gattcagcac cgggatttga agcaccgcaa
    35401 gaatctgtta caattttata agaaatattc tgagaacaat atcttatcct tatattccca
    35461 gcgagcagga gatggtgtga gtcctgcatt ccctatcgat aagattatcc tctcaaaaac
    35521 tcaagtctga agctagtaag atttgacgtt ccccacgtta cgggataaga gggagaaaga
    35581 ctaaaacttt ttccgaataa aggtggtacc acgattttcg tcctttttgg aagtcgtggt
    35641 ttttaatttg ttattattta taaaggagat accatgaaac tcaaagacac ccttaatctt
    35701 gggaaaactg aattcccaat gcgtgcaggc cttcctacca aagagccagt ttggcaaaag
    35761 gaatgggaag atgcaaaact ttatcaacgt cgtcaagaat tgaaccaagg aaaacctcat
    35821 ttcaccttgc atgatggccc tccatacgct aacggaaata tccacgttgg acatgctatg
    35881 aacaagattt caaaagatat cattgttcgt tctaagtcta tgtcaggatt ttacgcacca
    35941 tttattcctg gttgggatac tcatggtctg ccaatcgagc aagtattgtc aaaacaaggt
    36001 gtcaaacgta aagaaatgga cttggttgag tacttgaaac tttgccgtga gtacgctctt
    36061 tctcaagtag ataaacaacg tgaagatttt aaacgtttgg gtgtttctgg tgactgggaa
    36121 aatccatatg tgaccttgac tcctgactat gaagcagctc aaattcgtgt atttggtgag
    36181 atggctaata agggttatat ctaccgtggt gccaagccag tttactggtc atggtcatct
    36241 gagtcagccc ttgctgaagc agagattgaa taccatgatt tggtttcaac ttccctttac
    36301 tatgccaaca aggtaaaaga tggcaaagga gttctagata cagatactta tatcgttgtc
    36361 tggacaacga ctccatttac catcacagct tctcgtggtt tgacggttgg tgcagatatt
    36421 gattacgttt tggttcaacc tgctggtgaa gctcgtaagt ttgtcgttgc tgctgaatta
    36481 ttgactagct tgtctgagaa atttggctgg gctgatgttc aagttttgga aacttaccgt
    36541 ggccaagaac tcaaccacat cgtaacagaa cacccatggg atacagctgt agaagagttg
    36601 gtaattcttg gtgaccacgt tacgactgac tctggtacag gtattgttca tacagcccct
    36661 ggttttggtg aggacgatta caatgttggt attgctaata atcttgaagt cgcagtgact
    36721 gttgatgaac gtggtatcat gatgaagaat gctggtcctg aatttgaagg tcaattctat
    36781 gaaaaggtag ttccaactgt tattgaaaaa cttggtaacc tccttcttgc ccaagaagaa
    36841 atctctcact catatccatt tgactggcgt actaagaaac caatcatctg gcgtgcagtt
    36901 ccacaatggt ttgcctcagt ttctaaattc cgtcaagaaa tcttggacga aattgaaaaa
    36961 gtgaaattcc actcagaatg gggtaaagtc cgtctttaca atatgatccg tgaccgtggt
    37021 gactgggtta tctctcgtca acgtgcttgg ggtgttccac ttcctatctt ctacgctgaa
    37081 gatggtacag ctatcatggt agctgaaact attgaacacg tagctcaact ttttgaagaa
    37141 catggttcaa gcatttggtg ggaacgtgat gccaaagacc tcttgccaga aggatttact
    37201 catccaggtt caccaaacgg cgagttcaaa aaagaaactg atatcatgga cgtttggttt
    37261 gactcaggtt catcatggaa tggagtggtg gtaaaccgtc ctgaattgac ttacccagcc
    37321 gacctttacc tagaaggttc tgaccaatac cgtggttggt ttaactcatc acttatcaca
    37381 tctgttgcca accatggcgt agcaccttac aaacaaatct tgtcacaagg ttttgccctt
    37441 gatggtaaag gtgagaagat gtctaaatct cttggaaata ccattgctcc aagcgatgtt
    37501 gaaaaacaat tcggtgctga aatcttgcgt ctctgggtaa caagtgttga ctcaagcaat
    37561 gacgtgcgta tctctatgga tattttgagc caagtgtctg aaacttaccg taagattcgt
    37621 aacactcttc gtttcttgat tgccaataca tctgacttta acccagctca agatacagtc
    37681 gcttacgatg agcttcgttc agttgataag tacatgacga ttcgctttaa ccagcttgtc
    37741 aagaccattc gtgatgccta tgcagacttt gaattcttga cgatctacaa ggccttggtg
    37801 aactttatca acgttgactt gtcagccttc taccttgatt ttgccaaaga tgttgtttac
    37861 attgaaggtg ccaaatcact ggaacgccgt caaatgcaga ctgtcttcta tgacattctt
    37921 gtcaaaatca ccaaactctt gacaccaatc cttcctcaca ctgcggaaga aatctggtca
    37981 tatcttgagt ttgaaacaga agacttcgtc caattgtcag aattaccaga agttcaaact
    38041 tttgctaacc aagaagaaat cttggataca tgggcagcct tcatggactt tcgtggacaa
    38101 gcacaaaaag ccttggaaga agctcgtaat gcaaaagtta tcggtaaatc acttgaagca
    38161 cacttgacag tttatccaaa tgaagttgtg aaaactctac tcgaagcagt aaacagcaat
    38221 gtagcacaac ttttgatcgt gtctgagttg accatcgcag aaggaccagc tccagaagct
    38281 gcccttagct tcgaagatgt agccttcaca gttgaacgtg ctgctggtga agtatgtgac
    38341 cgttgccgtc gtatcgaccc aacaacagca gaacgcagct accaggcagt tatctgtgac
    38401 cactgtgcaa gcatcgtaga agaaaacttt gcggaagcag tcgcagaagg atttgaagag
    38461 aaataagatt gaaaagtcta ggcaaaattc aatttgagaa gaaaagacaa ctaattttat
    38521 agtctattaa acgcattgta tcacgttttt gaacacctga tatgatgcgt tttttattta
    38581 ttttaaaaat ttgcgaggta tgacttttta tactcaacaa gaatcaaaga gaaacttagc
    38641 aagctaacag tagtaagata aaataggaat ttgatattag ggataaga
//
LOCUS       DAVLXH010000015        37267 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00028199
            SAMN33607166-rid17955573.denovo.015, whole genome shotgun sequence.
ACCESSION   DAVLXH010000015 DAVLXH010000000
VERSION     DAVLXH010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607166
            Sequence Read Archive: SRR23725544
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 37267)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37267)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721421.1
            Genome Coverage       :: 115x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:42:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,210
            CDSs (total)                      :: 2,161
            Genes (coding)                    :: 2,023
            CDSs (with protein)               :: 2,023
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 73 of 138
            Pseudo Genes (incomplete)         :: 60 of 138
            Pseudo Genes (internal stop)      :: 40 of 138
            Pseudo Genes (multiple problems)  :: 31 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37267
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607166-rid17955573.denovo.015"
                     /strain="AUSMDU00028199"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1349"
     gene            <1..1263
                     /locus_tag="VYO11_000832"
     CDS             <1..1263
                     /locus_tag="VYO11_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000927610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1595421.1"
                     /translation="VYIDFNPTDSRNPADYRWTRWKGRDGANGVAGRAGADGRTPYVH
                     FAYSENADGSGLTMTDNGQRYFGHYSDYEKPDSSDKTKYKWADRWAKVDGGYVNIYAL
                     SKNRSIGKSYHVSEFNMDVLSGNITLKAIGSDPYIGAVSSHPGIFIKQQGMKIPVIQG
                     RSICITITNPLFRKNYISFFNSLGKTVKTYKHYNTNKFLISSADLVGVEFIALRYGAG
                     SSNIQIGTVLETKVKVEYGTVHSDWSPAPEDIESNINSKADQGLTQEQLNALNEKSQI
                     LEAEMKAKASMEAFSELEKAYNAFVKLNADSQKKSESDLVEAGRRIDLLTTQFGGLAE
                     LKTFIDTYMKSTNEGLIIGKNDASSTIKVSSDRISMFSAGKEVMYISQGVINIDNGIF
                     TASIQIGRFRTEQYHLNKDVNVIRYIGG"
     gene            1274..3352
                     /locus_tag="VYO11_000833"
     CDS             1274..3352
                     /locus_tag="VYO11_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000159973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="structural protein"
                     /protein_id="HEV1595422.1"
                     /translation="MTKFINSSGSLHLNIYIEQVSQDIANNSSRVSWKATVDRDGAYR
                     TYTYGNISNLSVWLNGSSVHSSHPNFDTSGQEFTLASGEVTIPHSGDGTKTFAVWASF
                     DPNNGVHGNITVSANYTLSSIPRSSSVSDNALSGNRRLGSPHTLTIDRKSSLFTHQVW
                     YRVFGSNWIDLGKNHATGVSFVPNIDLARYNTKAKSGTMDICVRTYNGTTQVGNDVYS
                     NGWYFEIPESVKPTFSGITLTDMNTVARQLLSGNNFLQIISDIQVNFNNPSGAYGSTI
                     TGYRAEIVNKNQVTTVNGGRLGMMNFNGSATIRASVVDSRGRQSDTRDITINVIEYFA
                     PAFSFTAFRTRETPNIIQVVRNAKIAPITLSGSQKNVMTLSFKVARLGSTTFTADHGR
                     ASGIWTTQHTLNNSAANMAGNYVATKSFVVIGTLSDKFTSTEFTATVATESVVMSYDK
                     DGRVGIGKVAEQGGAGSLDVLGDIYARNKPIQQYQLTDNNGCGKLIKQDFNTMKETGT
                     WWINGSSQNNPFSGTWGMLEVFRPNPGSHERIQRFTTSTGYMAVRENGFDNNWRPWRY
                     LVQQSKSTNNSDYVALLKSESTPTPWQNAILQNGWNHHRDYGGVQFSKTFDGVVCFKG
                     TCKGGKIARESIILTLPEHFRPSTTLFKTALNNDYGSAVIGIYPNGNVVVKSNVDATW
                     LNFDNVFFKI"
     gene            3412..3675
                     /locus_tag="VYO11_000834"
     CDS             3412..3675
                     /locus_tag="VYO11_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000922101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1595423.1"
                     /translation="MLKVTKTRQLVTEFFAQDGDQQKLVKTTVINTDNKAVSTISETL
                     HDPDLYANNRISMRKHEQELREMRYKIEDAILAELEADSEHKE"
     gene            3685..4101
                     /locus_tag="VYO11_000835"
     CDS             3685..4101
                     /locus_tag="VYO11_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003038967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HEV1595424.1"
                     /translation="MKIEFFNFLRSVVQTEDGLVLYALTLIVSMEIIDFVTGTIAAII
                     NPDIEYKSKIGINGLLRKISGVLLLMILIPASVLLPEKTGFAFLYSICLGYIAFTFQS
                     LIENYRKLKGNVTLFQPIVKVFQRLFEKDDDTKKGE"
     gene            4105..4434
                     /locus_tag="VYO11_000836"
     CDS             4105..4434
                     /locus_tag="VYO11_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001186229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HEV1595425.1"
                     /translation="MQQITEIITNGAISILVVLAGVVVRAVKDYLVQKGGEKTIKIVE
                     ILAKNAVNAVEQVAAETGYKGDEKLAQARAKVRAELTKYNISMTDKDLDTFVESAVKQ
                     MNDAWKG"
     gene            4441..5397
                     /gene="lytA"
                     /locus_tag="VYO11_000837"
     CDS             4441..5397
                     /gene="lytA"
                     /locus_tag="VYO11_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase LytA"
                     /protein_id="HEV1595426.1"
                     /translation="MDIDRNRLRTGLPQVGVQPYRQVHAHSTGNRNSTVQNEADYHWR
                     KDPELGFFSHVVGNGRIMQVGPVNNGSWDVGGGWNAESYAAVELIESHSTKEEFMADY
                     RLYIELLRNLADEAGLPKTLDTDDLAGIKTHEYCTNNQPNNHSDHVDPYPYLASWGIS
                     REQFKQDIENGLSAATGWQKNGTGYWYVHSDGSYPKDKFEKINGTWYYFDGSGYMLSD
                     RWKKHTDGNWYYFDQSGEMATGWKKIADKWYYFDVEGAMKTGWVKYKDTWYYLDAKEG
                     AMVSNAFIQSADGTGWYYLKPDGTLADKPEFTVEPDGLITVK"
     gene            complement(5703..6845)
                     /locus_tag="VYO11_000838"
     CDS             complement(5703..6845)
                     /locus_tag="VYO11_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEV1595427.1"
                     /translation="MWMEELSNGKYKFFERYKDPYTEKLKKVSVTMEKKTPQARNQAA
                     ILLQEKIKQKLGEKQHSVSNITFEKLYEEFEENWKHGVKNSTVYASKNVKKEILKQIE
                     GDYLVRNIDRRLLQKVIDQLLQDGRSHNYVSKIKFKLNQIMKFAIRMNYIDTNEMLFV
                     ETPRKVITSDELRKKNTKYLDQKEFKLFIQNLKDEALCDYRITKYIRIAKVLFLTGMR
                     YGELAALNYKEDIDFSKKTIHIKHTYDFRQKERTTPKTIKSDRVITAPQKVLDIIKEQ
                     IIENATNGFDTDFIFINTLGEPITNARIICAWKRHGQKIGIEKNITTHTFRHSHISLL
                     AELGIPLTAIMDRVGHSDSKTTLEIYSHVTQKMVSDISSKLEKIKL"
     gene            complement(6964..7479)
                     /locus_tag="VYO11_000839"
     CDS             complement(6964..7479)
                     /locus_tag="VYO11_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000821078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1595428.1"
                     /translation="MKRIFSISSVLLCALVISTACTNQTQKSSSEPTTQASSSDDISV
                     EEYFDKLLTKVDKVTKDNYKSDDYKIYDYKTVLREPEKFFSLKMRIDNLEIVQIFKEG
                     KYTKMLATQPNGDFYMLFMETERIEKRFLEKDHLTVNGRYLLSYEYTTNSNKEKSVPL
                     IYVDAYLMLKN"
     gene            complement(7497..7877)
                     /locus_tag="VYO11_000840"
     CDS             complement(7497..7877)
                     /locus_tag="VYO11_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HEV1595429.1"
                     /translation="MTEKEFSQNLGIDIEIFEDGLFPDEAFYIPALKTMFLSDAISDE
                     KRVQVALHEIGHRNHAPDTYQLFREKCELEANRNMIHHLMKAELDIAEDATTFNYLVF
                     MEKYNLKTIADEIMVKEEYLALLN"
     gene            complement(7899..8261)
                     /locus_tag="VYO11_000841"
     CDS             complement(7899..8261)
                     /locus_tag="VYO11_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1595430.1"
                     /translation="MFETFEKIKSLAKKQGISLNTLEDRVGLGKNYIYSLKNKKTPSA
                     EHISKIADYFNVSTDYLLGRTDNPTIANKKEQFFFEGKEVDVEELASTAMRFNGKPLT
                     EEDKKAIQNIIEIYLRKQ"
     gene            8558..8749
                     /locus_tag="VYO11_000842"
     CDS             8558..8749
                     /locus_tag="VYO11_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001112859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEV1595431.1"
                     /translation="MPDITNGREKVNDFLKDKGIKKTSLAIAYGFKRQEVTNILSGTT
                     KGPRANSFILQVIEDYGIE"
     gene            8927..9190
                     /locus_tag="VYO11_000843"
     CDS             8927..9190
                     /locus_tag="VYO11_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEV1595432.1"
                     /translation="MVVLANHPNWQVYPDEIAKRKGVGRDMIDRHLKKLEDAGYMRVI
                     KKSLGRGRGVQTFRFFSDTKITDFQFEIMLQRLDEAIEKLSTV"
     gene            9401..9652
                     /locus_tag="VYO11_000844"
     CDS             9401..9652
                     /locus_tag="VYO11_000844"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1595433.1"
                     /translation="MKQLKLSIKPKQEPTEGQCLNSSGYSVKINDWELGRGVIDFKLE
                     MPADKKPKITITAIPDVMEIDATVIAEIQKLQSESDIES"
     gene            complement(9623..9832)
                     /locus_tag="VYO11_000845"
     CDS             complement(9623..9832)
                     /locus_tag="VYO11_000845"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1595434.1"
                     /translation="MSFDKNIADKILEFAKLEQTVPVGTSHDFRSEEFDQDDFRDTAK
                     KLISTGQISGHLEEDFSGFYIAFRL"
     gene            9898..10116
                     /locus_tag="VYO11_000846"
     CDS             9898..10116
                     /locus_tag="VYO11_000846"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1595435.1"
                     /translation="MNELVLSNNPSQIELEIKRFLSVPLKLKILRECLLYLFFKMAND
                     TTDITVEKSTVHSSDGARKTVYTVTVYD"
     gene            10191..10457
                     /locus_tag="VYO11_000847"
     CDS             10191..10457
                     /locus_tag="VYO11_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000450962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1595436.1"
                     /translation="MEAVQIVRIKDVIIEKISGNDEELSHIFGCTKRQAGDMRREMKK
                     LPSQQKHLRNDGQLVTIKGFDAYLQYRGSQSWKKEMAKTVKMTR"
     gene            10541..10993
                     /locus_tag="VYO11_000848"
     CDS             10541..10993
                     /locus_tag="VYO11_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001134280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1595437.1"
                     /translation="MPNWAEGTLKLRGRRENVASALKEMLLGNKGATLEEEYDGTLLI
                     FKNEYDYFYINGTRRAFISSKDIEIWLDDDFVIIELEDFKQAWAASADNYTEISSKFD
                     VDIKIFTFEMGMEFTQEIEISKGEIIKNIVNENFTNYSWDVPFSRLGG"
     gene            10999..11706
                     /locus_tag="VYO11_000849"
     CDS             10999..11706
                     /locus_tag="VYO11_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000774580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ERF family protein"
                     /protein_id="HEV1595438.1"
                     /translation="MADLTFAELQRKMQIEKQTKQGVKYPFRTAEDINNKFKSLDSGW
                     SVSFPEDDIIQKGDKLYYKAVAVAKRESDGTIEKAIGWAREEDVPIFHTQKGDVKQMQ
                     DPQWTGAVGSYARKYALQGLFAIGGEDVDEYPVEESQEQGQNNQQQKPNNQQAQGQNQ
                     VRYIDNIQYQEINDLINDIAKIKGMPFDTLANYVLSEKLKGLQDFHRVQVGDYEVLKN
                     YLTEQLAKAKAKAKRGN"
     gene            11709..12701
                     /locus_tag="VYO11_000850"
     CDS             11709..12701
                     /locus_tag="VYO11_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000237813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1351 domain-containing protein"
                     /protein_id="HEV1595439.1"
                     /translation="MVKDVTNSLTEIKVDFQPAVINVDREAIEAQVAAAIAQYSGREV
                     TVDNYKEVYEERTRFNKLIGGLDTQRKDFNRQINEPAKDFDKWVKEKVIKPIEGVTDA
                     MSAGLNAIDEHERLMRVDVVRATFEDKCMVAGIEKSTFADKYDEYSLKKYFKTGKYEL
                     KKTTLDEMDGLVLSEFDALEEYKANKQAIQEQAQEYDLPADSYIRHLEDGKSLVDILK
                     MMKTDRDAEIARKEQKEAQEKAKAERLEEIAQSAKKNANANIKAYDAETGEILEQGTI
                     TPEPQNNAREVAKFEPSEPLVKLVRLELHGGLEQWENTQEYFEDNFIGFETLED"
     gene            12723..12899
                     /locus_tag="VYO11_000851"
     CDS             12723..12899
                     /locus_tag="VYO11_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001203349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1595440.1"
                     /translation="MRCFYVSGKIADLDLGSEINAENSFMAAIEFVKRYTGLLKFGSN
                     EIKVSEVEEVQNDK"
     gene            12889..13434
                     /gene="ssb"
                     /locus_tag="VYO11_000852"
     CDS             12889..13434
                     /gene="ssb"
                     /locus_tag="VYO11_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000609607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEV1595441.1"
                     /translation="MINNVVLVGRLTRDAELRYTQSNIAVATFTLAVNRPFKNEAGER
                     EADFINCVIWRQSAENLVNWAKKGSLIGVTGVIQTRSYDNQQGQRVYVTEVVASNFQL
                     LESRNSQQNNQGHQDHHGGYQQQGYSNQGSSFQNGNSYGQQGSFLEGNTTNLVPDFTR
                     DNNPFGRPTNPLDISDDDLPF"
     gene            13460..14599
                     /locus_tag="VYO11_000853"
     CDS             13460..14599
                     /locus_tag="VYO11_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000670026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HEV1595442.1"
                     /translation="MKFLDLFAGIGGFRIGMESAGHECIGFCEIDKFARASYKAIHDT
                     KGEIELHDITTVSDDTIRGIGHVDVICGGFPCQAFSIAGNRRGFEDTRGTLFFEIARF
                     ASILKPRYLFLENVKGLLNHDRGNTFEVILSALDELGYDVEWQVLNSKDFGVPQNRER
                     VFIIGHSRKRGTRRVFPIGRANREFDFEPKIKIVGNTKNPNGTSQGTGSVVYDSNGLV
                     GTLCARDYKEPKQVAIPVLTPDRVNKRQNGRRLKKNGEPMFTLTAQDRHGILIKEATK
                     KGYAEATVGDSVNLSHPNSKTRRGRVGNQIANTLLTGESQGVVEPDFRIRKLTPRECW
                     RLQGFPDWAFDKAQEVNSNSQLYKQAGNSVTVNVISAIAQGLGGN"
     gene            14634..14837
                     /locus_tag="VYO11_000854"
     CDS             14634..14837
                     /locus_tag="VYO11_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000161128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1595443.1"
                     /translation="MTKIEIVMVLTTLMSITWAAIVTIHTMQAIKKHKAKVDYYQKPQ
                     VQCEIARHVLKNKWYSDGGEVFR"
     gene            14891..15325
                     /locus_tag="VYO11_000855"
     CDS             14891..15325
                     /locus_tag="VYO11_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014736106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1595444.1"
                     /translation="MDKKLIGLDLTHIADGGLQEKLDKELEKVFDNILDLNTDAKAKR
                     KVTITLTMSANEERTVVDTTMEVKSKFAPQNGVATTILIGRDFDTGQVHANELKSTVP
                     GQMYFDENGEILTDIGQPVAEIEQQAETKPDIIDFNKKKVGN"
     gene            15327..16064
                     /locus_tag="VYO11_000856"
     CDS             15327..16064
                     /locus_tag="VYO11_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014736105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1595445.1"
                     /translation="MTTENLKAALEYAVELNEHGLEILTAADGTEYYDANKFNLKELD
                     PKRYPKTLELSTLTSLVDYLKTDLNNLKNQRLIVAVEKNDEVCVWSENDELERRTLLV
                     DVKARIPELSFGRFLSSEQFNIMLQSNFIDDNDRGTLLEFASALKIENGAEIEDNGVS
                     QVATVKTGVASLAKGKAPNPVTLRPYRTFSEVEQPASLFVFRIDKQANMALFEADGKR
                     WVADAVGNIAAYLKEQLADQKLITVLA"
     gene            16081..16293
                     /locus_tag="VYO11_000857"
     CDS             16081..16293
                     /locus_tag="VYO11_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001286809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1595446.1"
                     /translation="MSDYKQRMIEEYKQLKERTNKLSLMISNYYVGTLDFKLKCPIEL
                     LETQHYTMCAYLKILEQRAEIENIEF"
     gene            16304..16705
                     /locus_tag="VYO11_000858"
     CDS             16304..16705
                     /locus_tag="VYO11_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000667208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1595447.1"
                     /translation="MKFEFSLPRNTKLKSLNMVINSNDRQHQTDKAKVTKRIRAFAYW
                     HTSMDKDKGRAAFSPSNPCEVTVTIYSPTKSKLDPPNLYPTVKAIIDGMTDAGIWTDD
                     NHKVIKKLSFVYGGLSEEKGHYRLEFDIEEV"
     gene            16707..16913
                     /locus_tag="VYO11_000859"
     CDS             16707..16913
                     /locus_tag="VYO11_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000573749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1595448.1"
                     /translation="MIEVNIKFDNFEAHGFYQDDTKLGKIRDAIISQMNNGHVVILGE
                     DRSILLNPKVIKCVQFEVVEDDQI"
     gene            16963..17277
                     /locus_tag="VYO11_000860"
     CDS             16963..17277
                     /locus_tag="VYO11_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001854688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1595449.1"
                     /translation="MEELKKKVNEVYNWTVEDGKPQPPKQDLPQAVKDRADYFWEMAE
                     DGMTFMGAMECIFADEKPTDYDLGATKDWLPKSKEFDDWIGYAPSMAQVVIAVYLIYR
                     GN"
     gene            17279..17779
                     /locus_tag="VYO11_000861"
     CDS             17279..17779
                     /locus_tag="VYO11_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HEV1595450.1"
                     /translation="MNIKALIKKYEELWNEHSPFYEPVPYTSMVELFLKELKQLDEPE
                     KVKVPQFMADWIDYFKKNGDWDLFQAMDYLFGKKEIREWLEYKNNQDLFARAWLDGYE
                     VEKEKRYLVTLKNRQPLVKSQSGSTLYFSQDITARNYKGTQKELEDAKFGWVFDCPGI
                     EIEEVK"
     gene            17779..18072
                     /locus_tag="VYO11_000862"
     CDS             17779..18072
                     /locus_tag="VYO11_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1595451.1"
                     /translation="MTQTLEEGMKNQSKCIKIPMEIRPFDIGYRIVNQHGNPLALKNG
                     ASIFDLPSLAEKAIKKEFSKDDPDFDIEKHFVEEVAIVNLSKFHSYFEEVIHD"
     gene            18072..18464
                     /locus_tag="VYO11_000863"
     CDS             18072..18464
                     /locus_tag="VYO11_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1595452.1"
                     /translation="MTKKKIERLSVIHRREINWLKWYFLRDKKNPKRTILEQKIIVSH
                     IKTDRLEAKFLSNLKKSTEDFIDKSDPKYLRAIKEVYVYENMNVIGACQKILFYSPTQ
                     AYVLLNAWFNDYFRATYTELLENAILDK"
     gene            18530..19624
                     /locus_tag="VYO11_000864"
     CDS             18530..19624
                     /locus_tag="VYO11_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000425577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4417 domain-containing protein"
                     /protein_id="HEV1595453.1"
                     /translation="MEMLQIEYVDIKSIKPYHKNARHNDGEATEKVAASIKAFGFQQP
                     ILVDDNNIIITGHTRLKAALSLGIDTIPIAHAVNLTDEQIKAYRLADNRVAEYSTWDS
                     ELLNIELSQFETIDMAQFGFELSVTGFNFGNEEEQQEETENEEEDAEDFHRDTTINQY
                     NLFHYDDTRVEGFYNMPKIEGVDHIPKDFQGFNYVLNKPDYSSCVHFFLDDYQFERIW
                     QRPDFYIEKLLEFDSALAPDFSLYLDMPIAMQVWNIYRSRLIGQIMQDYGLTVIPTVS
                     WASEESFDFCFDGLPKNSTLAISTIGVKQNKEQFEVWKNGVTEMIKRLTPKRIVVYGG
                     KVEYDYKDIEVVYFENATTERMKESGTKTN"
     gene            19605..20351
                     /locus_tag="VYO11_000865"
     CDS             19605..20351
                     /locus_tag="VYO11_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000057536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1595454.1"
                     /translation="MAQKLTKLKDIFKHVSSIDLGKEILFEDLELYNKETETSKQYQS
                     IEEAENDLSLMEKVNKINFTLGGGRGANFEKGKDGKYPGFRGAGGARDSGSSKALHPA
                     SLNNQGRFSSVEGTIQEFIKKHGGSRTEYSTAVDSQGFAHNYVHGGKNSVQILPISGG
                     FTAIHNHPNGSNFSSTDLHSFAALKGMNTLVATNSSKAYRITKGANFDAKGFDKAVSK
                     SRFTTKDYNKGADLWLKKNAKKYGYTYSYE"
     gene            20555..21010
                     /locus_tag="VYO11_000866"
     CDS             20555..21010
                     /locus_tag="VYO11_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001136855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stress-induced protein"
                     /protein_id="HEV1595455.1"
                     /translation="MPRDGTKNLKPVTERTKDEARAISSKGGKASGIARRKKADLKKA
                     FEILLSLDVTDSKIKKQLEEMGMAGNNEALLAFATFQQAVKGNQKATENIIKLTNTKD
                     KYDIQEQKERIKALKYENRERAEAEKGSSETIEIVDAWAEDVRGATDDL"
     gene            21000..22310
                     /locus_tag="VYO11_000867"
     CDS             21000..22310
                     /locus_tag="VYO11_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000143806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBSX family phage terminase large subunit"
                     /protein_id="HEV1595456.1"
                     /translation="MTFNVQKNINPHFKSVWISSLPYNVLKGGRNSFKSSVIVLKLAY
                     MMIRYIIAGEAANIVVIRKVANTIRDSVFNKVWWALNLFGIAEQFTKTVSPFKIVHKT
                     TGSTFYFYGQDDFQKLKSNDIGNIIAVWYEEAAEFNDQEDFDQSNVTFMRQKHPRAKF
                     VQFFWSYNPPRNPYSWINEWFESIKTNKNYLAHSSTYLDDELGFVTEQMLEDIERIKE
                     NDYDYYRYLYLGEAVGLGNNVYNMSMFHAIDALPSDDKLIGISFALDGGHQQSATACC
                     AFGITAKGKVILLDTWYYSPAGQVVKKAPSQLSKEIYAYMRSVIEKYRVQALQYTIDS
                     AEGALRNQMFLDFGLKWHPVAKLRKVTMIDSFQSLLAQGRFYYLNTENNKIFIEEHKM
                     YRWDEKTIKSDNPSVIKEDDHTCDTTQYFVLDNAKLLGLRVGNV"
     gene            22323..23891
                     /locus_tag="VYO11_000868"
     CDS             22323..23891
                     /locus_tag="VYO11_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HEV1595457.1"
                     /translation="MSLFQKVKDFFSRGRYYMQTSNLNSILEHPKIAVTQEEYDRIKR
                     NLVYYQSKWDDVQYKNTDGDIKSRPMNHLPIARTASKKIASLVYNEQATITTKNEILQ
                     KFLDDMLTNDRFNKNFERYLESCLALGGLAMRPYIDGDKVRVAFIQAPVFFPLESNTQ
                     DVSSAAILTKTIKSEGRKNVYYTLVEFHEWVTADGQETGSTNDKKYYRITNELYRSDV
                     NDVLGQRVNLSELDKYKNLEPVTVFENLSRPLFTYLKTPGMNNKDINSPLGLSIFDNA
                     KTTIDFINRSYDEFMWEVRMGQRRVIVPEHLTQRQYQRPDGTIDFRPRFDVEQNVYMQ
                     IGGSSMDAGGITDLTSPIRANDYILAISEGLKLFEMQIGVSSGMFTFDGQGMKTATEI
                     VSENSDTYQMRSSIVALVEQSIKELCVSMCELGKAVGVYSGEIPELDDISVNLDDGVF
                     TDRHAELDYWAKMVAAGFSTKKRAIGKTLNISGVEAEKELNAINSELLPMNDAELAIY
                     GMHDQNEEEADDKG"
     gene            23878..24051
                     /locus_tag="VYO11_000869"
     CDS             23878..24051
                     /locus_tag="VYO11_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000161347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1595458.1"
                     /translation="MTKVKFGVTSVDYSASIEDTPTIKLGLIIRGSGRLDASSVIKKL
                     IKDVSELEYELEE"
     gene            24094..25245
                     /locus_tag="VYO11_000870"
     CDS             24094..25245
                     /locus_tag="VYO11_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000730221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage minor capsid protein"
                     /protein_id="HEV1595459.1"
                     /translation="MKKKRKQLTFNDQQFPLQMQGVGDIYEKLQIDIFDRMIKRLKER
                     GSIDLMRNPYIWQLEKLNDMHMLNEQNLKLISERTGIAERLLRDVIENEGLKVYKDTK
                     QQLEEDLNKIPEGEISNGVTDSLEAYSRQAVSDLNLINTTLPKSLQVAYKSIVEETVA
                     QVVAGTKTSDVALHDTIMKWQKNAFTGFVDKGGRHWKADSYARAIIKSTTYKVYNEMR
                     TRPAEELGVDTFYYSMKAMARPACSPLQGQIVTKGTGREIDGITIYSLLDYGYGTAAG
                     CLGIHCGHYLTPFIVGVHELPNLPDYLKNLTPEQAEENARIEAGQRGLERLIKTHKER
                     LHYAHTLQDDKMIQAERLKVRGYQTKIRNLINQHDFLTRDYRREKLYIS"
     gene            25384..25947
                     /locus_tag="VYO11_000871"
     CDS             25384..25947
                     /locus_tag="VYO11_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000896122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage scaffolding protein"
                     /protein_id="HEV1595460.1"
                     /translation="MAFTTEELLNLGLTEEQAKSVFALRGKELNEDKSALETIKQERD
                     SLKSQLQKAEEQVEHLKSLENISAEQKDAIDKLQAEYDKYKNEAAAELAQTKKVSAIS
                     LALKDTNAFNPDKLMKFIDVDAIQLDDNGKPQIDEVINGLKESDPYLFKAEESKPSPN
                     ILPQGNPAGEGTSDVDPFQAIIDGYGK"
     gene            25965..26846
                     /locus_tag="VYO11_000872"
     CDS             25965..26846
                     /locus_tag="VYO11_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001139822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage capsid protein"
                     /protein_id="HEV1595461.1"
                     /translation="MPSNQNNAVRRYEKQYAGILETVFGVRAAFSNALAPIQILDGVQ
                     ENSTAFSVKTNNTPVVISEYKTGENDGGFGDNSGAQSRFGGLTEVKYENTDVNYDYTL
                     TIHEGLDRYTVNNDLNAAVADRLKLQSEAQTRTVNKRIGKYLSDNATKTEALADFTDD
                     KVKALFNKLSAFYTNNEVTAPITVYLRSEFYNAIVDMASVTSAKGATISLDENGLPKY
                     KGFTLEETPAQYFETGVIAIFSPNGIIIPFVGISTARVIETENFDGVKLQAAAKGGTY
                     TLDDNKKAIYKVTGTIV"
     gene            26857..27090
                     /locus_tag="VYO11_000873"
     CDS             26857..27090
                     /locus_tag="VYO11_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001240344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1595462.1"
                     /translation="MALYKATKNLFFEQLNMDVIVNDIIELDEDYAKEVNKKLKNAFP
                     DVKNVLELVDKNGTLEPEDAPSVEDASQATVED"
     gene            27133..27525
                     /locus_tag="VYO11_000874"
     CDS             27133..27525
                     /locus_tag="VYO11_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013794407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1595463.1"
                     /translation="MTYLTQEEFDELGFDEVTDFEKLAKQAKIAIDLYTNGIYQKDID
                     FEKEIAYRKSAVQLAMAFQIAYLDASGIMSADDKQLANSVSIGRTSISYSTSQSTSAG
                     QRFNLSMDAENALRQAGFSLVVGVAYDR"
     gene            27515..27886
                     /locus_tag="VYO11_000875"
     CDS             27515..27886
                     /locus_tag="VYO11_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsid protein"
                     /protein_id="HEV1595464.1"
                     /translation="MIDKRLLKGIDKRLLKDVLTIKKVADKNDYGDEVYSEPLTIKNV
                     RFDRSVGRSGNRNSKTGTGNSKSRQKQGVIYLYPSLSFVTVDNSWMGAKVNDGIGDYT
                     INGFQTNYYDGEIFSQEIEVI"
     gene            27886..28230
                     /locus_tag="VYO11_000876"
     CDS             27886..28230
                     /locus_tag="VYO11_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsid protein"
                     /protein_id="HEV1595465.1"
                     /translation="MSIAIKVDLQKAKQKLSNESMTRGKIAVASKILLDNEQYIPLRG
                     GELRASGRIVGQGDAVVYGTVYARAQFYGANGIVTFRRYTTPGTGKRWDQVATSKHAE
                     EWARAFVKGMGL"
     gene            28230..28637
                     /locus_tag="VYO11_000877"
     CDS             28230..28637
                     /locus_tag="VYO11_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015968622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsid protein"
                     /protein_id="HEV1595466.1"
                     /translation="MRENDFQNVLLKHIKTLNLPVEPRFDYFEDDKDDLVINQIPGGK
                     VDREYMDGTQEVSLPFEIAVKAKKNSVANDTIWLVTSELAKIDLVLPSDNNSYEYMGM
                     EVSRPAMKGKDEQGYYYYTIEIVAKIVIERNKQ"
     gene            28634..29083
                     /locus_tag="VYO11_000878"
     CDS             28634..29083
                     /locus_tag="VYO11_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000198230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEV1595467.1"
                     /translation="MTRQKNALRGHFVAPYNGGTEPSTEDTWLELAKWISDVSDDTDE
                     KTDDQAYYDGDGVEETTVVSVKGAYTFEGTYDPDDKAQALIAGMKYKTGDDRKLWHKV
                     VSSDRKKQWVGAATATEIKAGSGAASDYEAFGCKLSYNSTPKETGIG"
     gene            29148..29636
                     /locus_tag="VYO11_000879"
     CDS             29148..29636
                     /locus_tag="VYO11_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000129842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1595468.1"
                     /translation="MTDIQIELKRTGFPVKIGEVELWFDTSQESLMRFYDMEEELKRR
                     LVQYELDVVSANINNKIERDGVTKEVVAGAIELEKKQLEIQYDLIFGDGTFDKLYSIY
                     PDYNALNNALEQTAIMLHDKLEEVAEQHKTVVKERASHYLNKGKVTPIKNNKKQKKNK
                     KK"
     gene            29649..30218
                     /locus_tag="VYO11_000880"
     CDS             29649..30218
                     /locus_tag="VYO11_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000062051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1595469.1"
                     /translation="MSMKLNDALITNFSIADKEYDIDLSFNKVLDVFEILKEDEMTRL
                     EQAQLIVHLLTGQELYNIKEVVDCWIYIKEHFLGIEKETVQYDLLGNPMPKAKGEEEQ
                     EKLIDFEQDAEYIYASFLQAYGINLLKSQNKLTWTEFKALLNALPDNTIMQQIIEIRA
                     WKPEYGGDKNKMRKLQAKYSLGKEGEDNV"
     gene            30211..33492
                     /locus_tag="VYO11_000881"
     CDS             30211..33492
                     /locus_tag="VYO11_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001279481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tape measure protein"
                     /protein_id="HEV1595470.1"
                     /translation="MSDGKVTIVVDVDGNKVKVLNDELDKTAQKGDRGSSSLKKFAVG
                     SAVFQLAAKGAELLGEALGGAIQRFDTLESYPRVMQAMGHSTEDVTRSTKKLAAGIEG
                     LPTTLNEVVGTAQRLTSITGDINKSTDLTLALNNAFLASGSSSADASRGLHQFSQMLS
                     AGKVDMQSWKTLQETMPYALQKTAESFGFAGQSAQNDFYSALKEGRITFNQFSRKLVE
                     LNGGVGGFAELAKTNSKGIQTSFGNLKNAVVKGVANTIKALDDLTKAATGKTIAENFD
                     ALKVIINAAFGVIVNVIKASTPVFQTLFSILSTGASVISFLTPAIIGLVAALVTMRAI
                     NQAVKTTKDLISAWKTFKTTATGAIQIINLMTAAQATCGSVTKAQMVANLANNGALTA
                     SNLLYGVLTGSISLQTAATIAATAATTAFKAALTALTGPIGLVVTGIGLVVGVCVTLW
                     QWLTAESEETKRLKSEQEELVKSTDQLTDSVKQSAKERQKNLESVKGNTESYQKLADE
                     IVQLSQKTNKTAADKKNLKKKIDALNASVSGLNLAYDKNSDSLSHNSDQIKARISAME
                     AESTWETSQKNLLDIEQKRAEIGEQLKQIAEQRKKWNEESNVSDSVRKERLQELNDKE
                     TELKNTQTELQTEYEKTSQVQQAASEAMAAAAENGSNRQVVAYENMSKSQQKAIDDMR
                     TKYNELLETTTNMFEQIKYKSAISVDEMIANLQKNQEAVNNWATNLNTLAERGVNEGI
                     LAKLQAMGPQGGLYVQELVNASDEKLATLNEVFTQGGESAMNGLTAGMDTGALGITDK
                     IKGIVQSQVSSLQEEIAAADFSSLGQEIPNGVSQGIEQGASTAGESSKNMANDIKESF
                     TSEMDINSPSRVFNEYGGFITTGLAEGVDKGTNQPVSSVTNLANQIKKPFDSLQSDFT
                     YIGEMAMSGLNAGLWSGSGSVMATANSIAERVKATIKSALDIHSPSRAMRDEVGRFIP
                     QGIAVGIEADAGVVEKSMLRLKESMMIDTRPEIALGLNKKLGAQVTVKQSSKQTIAEK
                     IKVTMDKSSELLEKALDVAETAVRRPNEMYLNDGTLVARTGDKFAKYQSEQLRRDNRM
                     KGVLS"
     gene            33489..35003
                     /locus_tag="VYO11_000882"
     CDS             33489..35003
                     /locus_tag="VYO11_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015968624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail family protein"
                     /protein_id="HEV1595471.1"
                     /translation="MTKIMTFNGVDMSKFFRITDIIRPIGNKRSVSTDNAPLLGVNIQ
                     QVKIGEKEHIIKFDIKTTNAIEMEQLKHDLAGILNVLEPVKITYGDEPDKYYMGLPVD
                     EITPENLTRWFQRSELKIIIPDGVAHSTTLKNFDIDTNETSAPDRIVFNLTNTGTEPA
                     YPIIRIKHNSENGYIGVVNNRAAFELGNREEADTEKYRDSETLIDYRGTNILKGFQNG
                     TKGVAVTNDNKERLVGTLSTTSMWGRNHIELSNRGTVEKNRNNAQSLTWAIPVDSSGE
                     VGSLNDYLLWRQVFMAAVANQYGFIKVTVSDTDGNFLYGVETYKRYQTLDCEYSFFTT
                     DGKGGYKFIKWWYFTGTGAQVGKLDPFSAEKGWSELKRNDDRVQVFFDGSHYDFIIPE
                     IKDKKSAKIHITLGALRDWPLVSHMYVDEFMYRKDFVTKSRDIPNRYPIGSNVVINSE
                     DDSVYIDGISKVSEVVDGSHWPAIPPGKSQLELYFSRFVKKKPTVTIEFEERWI"
     gene            35005..>37267
                     /locus_tag="VYO11_000883"
     CDS             35005..>37267
                     /locus_tag="VYO11_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000927608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEV1595472.1"
                     /translation="MLLTIHDANLQKVAFIDNEKQGTLNYYDDTWTRSLATGSSTFEF
                     TVFKKAVKSDLPLAKAYHHLNEHAFVSFKYKGKSFVFNIMIVEENEQTIKCYCENLNL
                     ELINELANPYKSNKAMTFKEYCEAMDLLNYTHLSIGINEISDYKRTLEWEGQETKLAR
                     LLSLAKRFDAEIEFDTQLNADSTIKKFSVNVYHENDDNHQGVGRVRNDVIVKYGKNIH
                     SITRKVDKTGIFNTIRPTGKMPTVEEEPSGDKGSKSETVKNADGSTTKTTISTASDGT
                     KSKTIVHTKVTKLADKTRITTTTTTRSDGSIEQTVTTSKKGGASTSETKVLKKPNPKE
                     KTNTTEDVLTIEGLDEWEVKNEKGIVEFYQRGQALYAPISMQLYPSTFTHSTGELDQW
                     TRKDFHFETDEPNELRRLGYLKLKKYCYPAITYEVDGFVDADIGDTVKVHDDGFAPLL
                     MIQARVTDQKISFTNPLRNKTIFDNFKALENKLSADIQSAFERLFEAAKPYTIKLSTD
                     NGVIFKNQIGQSLVTPTLYKGGKPVVVGVTWRWALDGEVTTGMTYLVRGSNVTDTVTL
                     TVAAYIGNKEVAVDEISLVNVADGKLGTPGTPGRDGRTPYVHTAWANNATGTDGFSLD
                     SSINKLYIGIYTDFEPNDSTDPKKYKWAKVKGDKGEKGDKGEPGQRGLQGLQGARGEQ
                     GIPGPRGADGRTQYTHIAYSNSADGTKDFSVSASDRAYIGMYVDFNSADSNTPSDYNW
                     TLVKGSDGANGVAG"
BASE COUNT        12788 a         6131 c         8034 g        10314 t
ORIGIN      
        1 gtgtacattg actttaatcc aacagacagc agaaatcctg ctgattatcg ctggacaaga
       61 tggaaaggtc gtgatggcgc aaacggcgta gcaggtaggg ctggtgcaga tggtaggaca
      121 ccttatgttc actttgcgta ttctgaaaat gcagatggat caggtttgac aatgacagat
      181 aacggacagc gttattttgg tcattattca gattatgaga aacctgatag ttcggataaa
      241 actaagtaca aatgggctga tcgttgggct aaagttgatg gaggttatgt aaatatctat
      301 gcattgtcta agaatagaag tattgggaaa tcttatcatg tttctgaatt taatatggat
      361 gtactttcag gaaatatcac tctaaaagca attgggtcag atccatacat tggcgccgtt
      421 tcttctcatc caggtatttt tataaagcaa cagggaatga aaatcccagt tatacaaggg
      481 agatctattt gtataacaat aacaaatcct ttatttagaa aaaattacat ctcgtttttt
      541 aattcattag gtaaaactgt taaaacatat aagcattaca acacaaataa atttttaata
      601 tcttcagctg atttggtagg tgttgaattt atcgctttac gatatggtgc aggaagctcg
      661 aatatacaaa ttggaaccgt actagagaca aaagtaaagg tagaatatgg aaccgtgcat
      721 agcgactggt cgcccgctcc agaagatatt gaaagtaata ttaactctaa agctgatcag
      781 gggctgactc aagagcagtt aaatgccctc aatgagaagt cacagatttt agaggctgaa
      841 atgaaagcga aagcatcgat ggaggccttt agtgaattag aaaaagcata taatgccttt
      901 gtgaaattaa atgcagatag tcaaaaaaaa tctgagtctg atttagttga agcaggtaga
      961 agaattgatt tgctgacgac acaatttgga ggattagcag agcttaaaac attcattgat
     1021 acttacatga aaagcacaaa tgagggcttg attataggta agaatgatgc aagctctact
     1081 attaaggtat caagtgatag aatatccatg ttttctgcag gtaaggaagt tatgtacatt
     1141 tcgcaaggtg taataaatat tgataatggt atttttactg catcaattca aattggacgt
     1201 tttagaacag aacagtatca tcttaacaaa gatgtgaatg tcatacgata tataggaggt
     1261 taaaaagagg gaaatgacta aatttatcaa ttctagcggt tcactacact tgaatattta
     1321 catcgaacaa gttagtcaag atatcgctaa caattcctca agagttagtt ggaaagctac
     1381 tgttgaccgt gatggagctt accgcacata tacttatggt aatattagta acttgtctgt
     1441 atggttaaat gggtcaagtg tgcatagtag tcatccaaac tttgacacat ccgggcaaga
     1501 gtttacttta gcaagtgggg aagtaaccat cccacacagt ggtgacggaa ctaagacttt
     1561 tgcagtatgg gcatcgtttg acccaaacaa cggagtacat ggaaacatta ccgtatcagc
     1621 aaactatact ctttcaagca ttcctcgatc tagtagtgta agcgacaatg ctctttcagg
     1681 aaataggcgg ctcggaagtc ctcacactct cactattgat cgcaaatcta gcttatttac
     1741 tcaccaagta tggtatagag tgtttggtag caactggatt gatttaggaa aaaatcacgc
     1801 aacaggcgtt tctttcgtac ctaatattga cctagctaga tacaacacaa aagcaaagtc
     1861 tggcacgatg gacatatgtg ttcgaacata taatggaact actcaagttg gaaatgacgt
     1921 ttactcaaat gggtggtatt ttgaaattcc ggaaagcgtg aaacctacat tttctggaat
     1981 tacattgact gatatgaata ctgttgctag gcaactattg agcggaaata actttttaca
     2041 gattatttcc gacattcagg tcaactttaa taatccatcc ggggcttatg gttcgactat
     2101 cacaggatat cgtgctgaaa tcgtaaacaa gaatcaggtt acaactgtaa acggtggtag
     2161 gcttggtatg atgaatttca atggttcagc aacgattcga gctagtgtgg ttgatagccg
     2221 aggcaggcaa tcagatacta gagatattac aatcaatgtt attgaatatt ttgcaccagc
     2281 ttttagtttt acagctttta ggacgcggga aacacctaac attattcaag ttgtcaggaa
     2341 tgctaaaatc gctcctatca ctttatcagg tagtcaaaaa aatgtcatga cactatcatt
     2401 caaagtagct cgactaggta gtacaacttt tacagctgat catggtagag cttctggtat
     2461 ttggacaact caacacacct taaataattc agctgctaac atggcaggta attatgttgc
     2521 aaccaaatca tttgtggtca taggaactct atctgataag tttacaagca cagaatttac
     2581 agcaacagtt gcaactgaaa gtgtggtaat gagttatgac aaagatggcc gtgtgggcat
     2641 tggtaaagtt gcagagcaag gtggtgcagg gtcattggat gtcttgggag atatctacgc
     2701 tagaaataaa cctatccaac aatatcaatt gactgacaat aatggatgtg gaaaacttat
     2761 caaacaggat tttaatacga tgaaagagac tggaacgtgg tggataaatg gtagctctca
     2821 aaacaacccc ttttctggaa cttgggggat gctagaggta ttcagaccta atccaggctc
     2881 tcatgaacgt attcaacgct tcactacctc aacaggatat atggcagtta gggagaatgg
     2941 ttttgataac aactggagac catggcgcta tctggtgcaa caatccaagt ctactaataa
     3001 ctctgactat gtagctttgc taaaatcaga aagcactccg actccttggc aaaatgccat
     3061 tttacaaaat ggatggaatc atcacaggga ttacggaggt gtccaatttt caaaaacatt
     3121 cgatggtgtt gtttgtttta aaggaacatg taagggcgga aagattgcac gtgagtcaat
     3181 catacttact ttacctgaac atttcagacc atctacaaca ttattcaaaa ctgctttgaa
     3241 taatgattac ggttcagccg ttataggaat ttatccaaat ggaaacgtag ttgtcaaatc
     3301 taatgtagat gctacttggc ttaattttga taatgtgttt ttcaaaatat aacaaccgta
     3361 aaaaatccct aattattaac ggataattaa tttataaagg aggaaatgac aatgttaaaa
     3421 gtcactaaaa cacgtcagct agtaactgaa tttttcgcac aagatggcga ccaacaaaaa
     3481 ttggtcaaaa ctactgtaat caacacagac aataaagctg tttcaacaat atctgaaacg
     3541 ctgcatgacc cggatctgta cgctaacaat cgtatcagta tgcgtaagca tgagcaagag
     3601 ttacgagaaa tgcgctataa gattgaagat gccattttgg cagagctgga agcagattct
     3661 gagcataagg aataggaggt gtgtatgaaa attgaatttt tcaattttct aagaagtgtc
     3721 gtacagactg aagatggttt ggtcttgtac gctctaacac tgattgtctc aatggaaatc
     3781 attgattttg tcacagggac gattgcggcg attatcaatc ctgacatcga gtacaagagc
     3841 aaaatcggca ttaacgggct ccttcgtaag atttcagggg ttctcttact gatgatcctc
     3901 attccggcgt ccgttttgtt gcctgaaaag acaggttttg cattcttgta ctcaatctgt
     3961 ctcgggtaca tcgcatttac ttttcaatct ctcattgaaa attaccgcaa attaaaagga
     4021 aatgttactc tttttcagcc gattgtaaaa gtatttcagc gattatttga aaaagatgat
     4081 gatacgaaaa aaggagaata acaaatgcaa caaattactg aaatcattac taatggagca
     4141 atcagcatcc tagtcgtttt ggcaggggtt gtagttaggg cagtcaagga ctacctggtt
     4201 caaaaaggtg gagaaaagac catcaaaatc gttgaaatct tggccaaaaa tgcagtaaat
     4261 gccgtggagc aggtagctgc tgaaactggc tacaagggag atgaaaaact ggcacaggct
     4321 cgcgctaaag tccgtgctga gcttacaaaa tacaatatta gcatgactga caaagactta
     4381 gacaccttcg tagagtcagc agtgaagcag atgaatgacg catggaaagg atgataggga
     4441 atggatatcg atagaaacag actacgtaca ggcttgccac aggttggggt gcagccttat
     4501 cgacaagtac atgctcattc aacaggtaac cgcaactcaa ccgtacagaa tgaagcggat
     4561 tatcactggc ggaaagaccc agaattaggt tttttctcgc acgttgttgg gaacggtcgc
     4621 atcatgcagg taggacctgt gaacaacgga agttgggatg ttgggggcgg ttggaatgct
     4681 gagagttacg cagcggttga actgattgaa agccattcaa ctaaggaaga gtttatggct
     4741 gactatcgcc tctatatcga attgctacgc aatctagcgg acgaagcagg cttgccgaag
     4801 actcttgata cagacgactt ggcaggtatc aagacgcatg aatactgtac caataaccaa
     4861 ccaaacaacc actcagacca tgtggatcca tatccatatc ttgcaagttg gggcattagc
     4921 cgtgaacagt ttaagcaaga catcgaaaac ggcttgagcg ctgcaacagg ctggcagaaa
     4981 aatggcactg gctactggta cgtacattca gacggctctt atccaaaaga taagtttgag
     5041 aaaatcaacg gtacctggta ttatttcgat ggctcaggct atatgctttc agaccgctgg
     5101 aagaagcaca cagacggtaa ttggtactac tttgaccaat caggcgaaat ggccacaggc
     5161 tggaagaaaa tcgctgacaa gtggtactat tttgatgtag aaggtgccat gaagacaggc
     5221 tgggtcaagt acaaggacac ttggtactac ttagacgcta aagaaggcgc catggtatca
     5281 aatgccttta tccagtcagc ggacggaaca ggctggtact acctcaaacc agacggaaca
     5341 ctggcagaca agccagagtt cacagtagag ccagatggct tgattacagt taaataaata
     5401 gaaaggaaac tttctaaatt gttctttcac cgcaggctca ggcttgcggt ttttttgttt
     5461 taaaaaaggg gcaaaaaagg ggcaaaagtg tcgtaaacct ctgtaaaacg atgtaaaaaa
     5521 tcaactttgc cctcgcttta aagctctaaa tttcaacgta ttgtgaaaca gtgtaaatta
     5581 tcgtatcgcc tataattgtt gtgtgctctt ttttcgtgca ctttaaaaac cctttaaaat
     5641 caacacttta aggggttttt gtttgtcttg tataagaaaa aggggcaggt gaggggcata
     5701 atttatagtt taatcttttc taacttacta gatatgtctg ataccatttt ttgagtgaca
     5761 tgggaataaa tctctagtgt ggtctttgag tcactatgtc ctactctatc catgatggca
     5821 gtcaagggaa tgcctagctc agcaagtagg gatatgtgag aatgtctaaa tgtatgtgta
     5881 gttatgtttt tttctatgcc gattttttga ccatgtcttt tccatgcaca aataatcctg
     5941 gcatttgtta ttggttctcc tagagtattg atgaaaataa aatctgtatc aaatccattt
     6001 gtcgcattct ctattatttg ctctttgata atatctaaca ctttttgagg tgctgttata
     6061 accctatcgg acttgattgt ctttggtgta gttctttctt tttgtctgaa atcgtatgta
     6121 tgcttgatgt gaatagtctt tttagaaaaa tctatatctt ccttgtagtt taaggctgcc
     6181 agctctccat acctcatgcc agtaagaaaa agaactttag ctattcggat atactttgta
     6241 attcgataat cacatagggc ctcgtctttt aaattttgga tgaataactt aaactctttt
     6301 tggtctaagt attttgtatt tttctttctg agttcgtcgg atgtaattac ttttctaggc
     6361 gtttcaacaa atagcatttc atttgtatca atataattca ttctgatagc gaatttcatt
     6421 atctgattga gcttgaactt gattttagaa acatagttat gagatctccc atcttgtaat
     6481 agttgatcta ttactttttg taataaacgt ctatcaatat ttctaactag gtagtcgccc
     6541 tctatctgct ttaaaatctc tttttttaca ttttttgaag catagactgt tgaattttta
     6601 acaccatgtt tccaattttc ctcaaattcc tcatatagtt tttcaaaagt tatattagaa
     6661 acagaatgtt gtttttcccc taacttttgt tttatctttt cctgcaacaa gatggcggct
     6721 tgatttcttg cttgtggagt tttcttctcc atggttactg aaactttttt taatttctca
     6781 gtatatggat ctttatatcg ctcaaaaaat ttgtattttc cgttggaaag ttcttccatc
     6841 cacattgatt ttacctcact tttttgataa aatgggtaca agaaaactac ctttttaatg
     6901 gttgtttcct atacatgatt tcctcacact ctccttggcc aaaatttgag tgtggggatt
     6961 tttttaattt ttcagcatca aatacgcatc gacgtaaatt aaaggtacgc ttttttcttt
     7021 gttgctgttg gtggtatatt cgtaagaaag caagtaacgc ccgtttacag ttaggtgatc
     7081 tttttctaaa aatctttttt ctatacgttc agtttccatg aacagcatat agaaatcacc
     7141 gttaggttgt gtagcaagca ttttcgtgta cttgccttct ttaaaaattt gcactatctc
     7201 cagattgtcg attctcattt ttaaagagaa gaatttttct ggctctcgga gaacagtttt
     7261 gtaatcatag attttataat catctgactt gtaattatct tttgtgacct tatcaacttt
     7321 agtcaatagc ttatcaaaat attcttctac gctaatatca tcagatgatg atgcctgagt
     7381 ggtcggttcg ctggatgact tttgcgtttg atttgtacaa gcggttgaaa taacaagtgc
     7441 acaaagcaaa acagatgata tggaaaatat tcttttcatt ttatcctact cctttttcaa
     7501 ttaagtaaag ccaaatattc ttcttttacc attatttcat cggcaatggt ttttaaatta
     7561 tacttttcca taaataccag gtaattaaat gtagtggcat cttcggctat atccaactca
     7621 gctttcataa ggtgatggat catattccta ttagcctcaa gctcacactt ttccctaaaa
     7681 agctgataag tatctggcgc gtggtttcta tggcctatct catgtaaagc gacttgtacc
     7741 cttttttcat cagatatagc atcactcaaa aacatagttt tgagggctgg gatgtaaaag
     7801 gcttcatctg gaaatagacc atcttcaaaa atctctatat ctatgcctag attttgagaa
     7861 aattcttttt cagtcataaa caatccaacc tttgattatt attgttttct gagataaatc
     7921 tctattatgt tttgaattgc ttttttatct tcttcagtta gtggtttacc attgaagcgc
     7981 atagcagtag aggcaagttc ctcaacatcg acttctttgc cttcgaaaaa gaattgttct
     8041 tttttattag cgatggtagg attatctgtg cgaccaagta agtagtctgt agatacattg
     8101 aagtagtcag cgattttgga tatatgttca gcagatggag tctttttatt tttaagactg
     8161 taaatgtaat ttttccccaa accaacccta tcttctaaag tgtttagaga aattccctgt
     8221 tttttagcta aacttttaat tttttcgaat gtctcaaaca ttgatacatc aacctttctg
     8281 aagcattaca aaaaaatatt ttattttttc gcctaaaaca cttgacaaaa attagacgaa
     8341 caactaaaat agtatttgta agtaattaac aactaaaaaa acaactaaga aataaattat
     8401 aaaaatgttt ttgcgaacgg tatttataga tttattagtg tttttattat gctttcattt
     8461 tagacgaaca tctaaaaaaa gtcaagcgaa aagataaaaa atagttaaat ttttagttgt
     8521 ttcttattta caaaataagt aaaaaggagg aacacatatg ccagatatca caaatggtcg
     8581 tgagaaagtc aatgattttc tgaaagacaa aggtattaaa aaaacaagtc tagcgattgc
     8641 ttatggcttt aaacgacagg aagtaacaaa cattctgagt gggacgacga agggaccacg
     8701 agcgaacagt ttcattcttc aagtgattga agattatggg attgagtagg agggaataac
     8761 atgtaagata agtcaattat agcaaattta aaaggaggag ttatgacaga ctttaaaaat
     8821 ttagattgtc aatttatctt tcaagaatgc gactgaaaat tatactgctg ttagtaataa
     8881 ctttatcaat gatccaaaac tggggtttac agcggtaggt attatgatgg ttgttctagc
     8941 taaccaccca aactggcaag tctatccaga tgagatagct aaacgaaaag gtgtcggccg
     9001 tgacatgatt gatcgtcatc taaaaaagtt agaggatgct ggttatatgc gtgtgatcaa
     9061 aaaaagcctt ggtagaggtc gaggtgttca gactttcaga ttcttctcag atacaaagat
     9121 aactgacttt caatttgaaa tcatgttaca acggcttgat gaagcaatag aaaagttatc
     9181 cacagtttga tatttacatt tccgactttt acaaatttgt attttacaaa tctgtatttt
     9241 acaaatctgt aaaataaggc actaataaat actaactaac aacaagtatt aaataacaat
     9301 aaatattaaa agacaactag tcctacttct ctaaaaaata aaagagagaa atttaaaaat
     9361 ttctaatata ggactttgca aaaatgggaa aggagtactc atgaagcaat taaaactaag
     9421 tattaaaccc aagcaagaac ctactgaggg tcaatgtctt aattcttcag gatattcagt
     9481 aaaaatcaat gattgggagc ttggccgagg ggtaattgat tttaaactag aaatgcctgc
     9541 ggataagaaa ccaaaaatca ctatcacagc gattccagat gtaatggaaa ttgatgcgac
     9601 agtgattgct gaaattcaga aattacaatc tgaaagcgat atagaatcct gagaaatctt
     9661 cctcaagatg tcctgaaatt tgaccagttg agattagttt cttagcggta tctctaaaat
     9721 catcttgatc aaactcttca gaacggaaat catgagaagt gcctactggg acagtctgtt
     9781 ccagcttagc aaactctagg attttatcag ctatattttt atcaaatgac atttttaacc
     9841 ctcctttctg gtttcattat agcagaaaag gggattagaa acagaaagga ggaaagaatg
     9901 aacgaactag tattatcaaa taatcctagt caaatcgaac tggaaattaa acgatttcta
     9961 tcagttcctt taaaattaaa aattttacga gaatgtttgt tgtatttgtt tttcaaaatg
    10021 gctaacgata cgacagatat aacggtagag aagtcgaccg tacattctag cgatggagca
    10081 agaaagacag tctatacagt aactgtatat gactaaacaa aaaagcacct gacggcaatc
    10141 aggcgctcaa taaaattatt cagagtgatt atatcacgaa aggggcaaaa atggaagcag
    10201 ttcaaatcgt gagaattaaa gatgtgatca tcgagaagat ttctggtaac gatgaggagc
    10261 ttagtcacat tttcggatgc actaaaagac aagcgggaga catgaggcga gaaatgaaaa
    10321 aattgcctag tcaacaaaag cacctcagaa atgatggtca gcttgtcaca atcaaaggtt
    10381 ttgatgctta tctgcaatat cgaggcagtc aatcatggaa gaaagaaatg gctaaaaccg
    10441 ttaagatgac acgatagcag aataataact actaacaaat aacaaactca tacttataga
    10501 taataaggga attacagagt ttttaaagga ggaaagaaat atgccaaatt gggcagaggg
    10561 gactcttaaa ttaagaggca gacgcgaaaa cgttgcatca gctttaaaag aaatgctatt
    10621 aggaaataaa ggcgcaacgc ttgaagaaga atacgatggc actctactaa tatttaaaaa
    10681 cgagtatgat tatttttata taaacggtac aagacgtgcg tttatttcta gtaaagatat
    10741 tgaaatttgg ttggatgatg attttgtgat tatcgaactt gaagatttca aacaagcatg
    10801 ggcagcatca gctgacaatt acacagaaat ttctagtaag tttgatgttg atattaaaat
    10861 tttcactttt gaaatgggta tggaatttac acaggaaatt gaaatttcaa aaggtgaaat
    10921 catcaagaat attgtaaacg aaaactttac taactattca tgggatgtgc cttttagtag
    10981 acttggagga tagataatat ggctgattta acatttgcag aattacagcg aaaaatgcaa
    11041 atcgaaaaac aaacgaaaca gggagtgaaa tatccgttta gaaccgcaga ggacataaat
    11101 aataaattta agtctttgga tagtggttgg agtgtatcat ttccagaaga tgacatcatt
    11161 caaaaaggtg acaaactgta ttataaagcg gtagctgttg ctaaaagaga aagtgatggc
    11221 acgattgaaa aagctattgg atgggctaga gaagaagatg taccaatttt tcacacacaa
    11281 aaaggggatg tgaaacagat gcaagatcca caatggacag gtgcggttgg ttcttatgct
    11341 agaaaatatg ctttacaagg tttatttgcc attggaggtg aggatgttga tgagtatcca
    11401 gtagaagaaa gccaagagca aggacagaat aatcagcaac agaaaccaaa caaccagcaa
    11461 gcccaaggac aaaatcaagt aaggtatatt gacaacattc agtatcaaga aattaacgac
    11521 cttataaatg atattgcaaa aattaaaggg atgccgttcg atacgcttgc taactatgta
    11581 ctatctgaaa aattaaaagg tttacaagat tttcatagag tacaagttgg tgactacgag
    11641 gtattgaaaa actatttaac tgaacaacta gcaaaagcaa aagcaaaagc aaagagaggt
    11701 aattaaacat ggtaaaagat gtaactaata gcttgacaga aatcaaggtg gattttcaac
    11761 ctgcagtaat taatgttgac cgtgaggcga tcgaggcaca agtagccgca gccattgcac
    11821 agtatagcgg tcgcgaggtt actgttgata attacaaaga agtttatgaa gagcgaaccc
    11881 gctttaataa gctgattggg ggcttagaca ctcaacgcaa agattttaac cgacaaatca
    11941 atgagccggc aaaagacttt gataagtggg tcaaagaaaa agtcatcaag cctattgagg
    12001 gcgtaacaga tgctatgtca gcaggactta atgcgattga tgaacatgaa cgattgatgc
    12061 gcgtggatgt cgtgcgtgct acatttgagg ataagtgtat ggtcgcaggg attgaaaaat
    12121 ccacattcgc tgacaaatac gatgagtaca gcctcaagaa atattttaaa acaggcaagt
    12181 atgagctgaa aaagacaaca cttgatgaaa tggatggctt agtactttca gaatttgatg
    12241 ccctggaaga atacaaggct aacaagcaag ctatccaaga gcaagctcaa gagtacgatt
    12301 tgccagctga tagctatatc agacatcttg aagatggtaa gagtcttgtt gatatactca
    12361 agatgatgaa aactgaccga gatgctgaga ttgcacgcaa agagcagaaa gaggctcaag
    12421 aaaaagcaaa agctgaacga cttgaagaaa ttgctcaatc ggccaagaaa aatgctaatg
    12481 cgaatatcaa ggcttacgat gccgaaacag gcgagatttt ggaacagggt acaattacac
    12541 cagaacctca aaacaatgcg cgagaggtgg caaaatttga gcctagcgag cctttggtca
    12601 aattagtacg tcttgaattg cacggtggtt tagaacagtg ggaaaataca caagaatatt
    12661 ttgaggataa ctttatcggt tttgaaactt tggaggatta agtagaataa ggagtcagac
    12721 ctatgagatg tttttatgtc agcggtaaaa ttgcagatct tgatttgggg tcagaaatca
    12781 atgcagaaaa ttcatttatg gccgctattg agtttgtgaa acgatatacc ggcttattaa
    12841 agtttggttc aaatgaaatc aaggtatcag aagtagagga ggtgcaaaat gataaataac
    12901 gttgttttag tagggcgact tacaagagat gccgaactga gatacacgca atctaatatt
    12961 gcggttgcta cgtttactct tgctgtaaac cgtccattta agaacgaggc tggagagcgt
    13021 gaggctgatt ttatcaattg cgttatctgg agacagtcag ctgaaaatct tgttaattgg
    13081 gctaaaaaag gttctcttat cggagttaca ggagtaattc aaacacgtag ctatgataac
    13141 cagcaaggtc aacgtgttta tgtcacagaa gttgttgcca gtaattttca actgttggaa
    13201 agtcgtaaca gtcagcaaaa taatcaaggt catcaagacc atcatggcgg ttatcagcag
    13261 cagggctaca gtaatcaagg cagttctttc caaaatggaa atagttacgg gcaacaaggc
    13321 agtttccttg aggggaacac aacaaatcta gttcctgatt tcacccgtga taacaatcca
    13381 tttggcagac ccacaaatcc attggatatt agtgatgatg atttaccgtt ttagcgaaag
    13441 gggatattct agttaagtta tgaaattctt agacttattt gctggcattg gaggttttag
    13501 gatcggcatg gaatcagccg ggcatgaatg tataggattt tgtgaaatag acaaattcgc
    13561 tagagctagt tataaagcta tacacgatac gaaaggagaa attgaattac atgacattac
    13621 aacagtatca gatgacacta ttcgaggaat cggacatgtt gatgttatct gtggaggatt
    13681 tccgtgccag gctttcagca ttgcaggaaa cagacgagga tttgaagata caagaggaac
    13741 tctcttcttt gaaatcgcaa ggttcgcatc tattctcaaa cccagatatc tattccttga
    13801 aaacgtcaag ggactcctca accacgacag aggaaatacc tttgaggtca tcctctcagc
    13861 gttggatgaa ctggggtatg atgtggaatg gcaagtgctt aacagcaaag attttggagt
    13921 cccccaaaat cgggaacgtg tgttcattat cggacattct agaaaaagag gcaccagaag
    13981 agtttttcct atcggaagag caaatagaga atttgatttt gaaccaaaaa taaagattgt
    14041 tggtaacact aaaaatccga acgggacaag tcaagggact gggagcgttg tttacgactc
    14101 aaacggttta gtcggtacgc tttgcgctag agattataaa gagccaaaac aagtagctat
    14161 accagtattg acacctgata gagtaaataa acgacagaat ggtagacgtt taaaaaaaaa
    14221 cggtgagcct atgtttacgc tgacggcaca agaccgtcat gggattttaa ttaaagaagc
    14281 aacaaaaaaa ggttatgcag aggctacagt tggtgatagt gtaaacctat ctcatccaaa
    14341 ctctaaaaca aggcgaggta gagttggtaa tcagatagca aatactctct taactggaga
    14401 gagtcaaggt gtggttgagc ctgattttag gattaggaag ctaacaccta gagaatgctg
    14461 gaggttacaa ggttttcctg attgggcttt tgataaggcg caggaggtca actctaacag
    14521 tcaattatac aagcaagcag gcaatagcgt aacagtaaac gttatttctg caatagcaca
    14581 gggtttagga ggaaattaac cctatttaaa ccaatttgaa aaggaaacag aaaatgacaa
    14641 aaattgaaat cgttatggta cttacaactt tgatgtctat cacatgggca gcgattgtta
    14701 caattcacac tatgcaagct atcaaaaagc acaaggcaaa agtggattat tatcagaaac
    14761 cacaagtgca atgtgagatt gcacgtcatg tacttaaaaa caaatggtac tcagatggtg
    14821 gggaggtgtt tagatgaaag tatttgatgg cgctatttca aattagctta atttaaagca
    14881 ggaggacaat atggataaaa aacttattgg gttagatcta acccacattg cagatggagg
    14941 attacaggag aaactagaca aagagcttga aaaagtcttt gataacatcc ttgacctaaa
    15001 tacagatgcg aaagcaaaac gaaaagtgac tatcacactt acaatgtcag caaatgaaga
    15061 gcgtacagtt gttgatacta ccatggaggt gaaatcaaaa tttgcgcctc aaaatggagt
    15121 agctacaaca attcttattg ggcgtgattt tgatacaggg caagtacatg ctaatgagct
    15181 aaaaagtaca gtacctggtc aaatgtactt tgatgaaaac ggagaaattc tgacggatat
    15241 tgggcaacca gtggcagaaa ttgaacaaca agcagaaaca aaaccagata ttattgattt
    15301 caacaaaaag aaagtaggta actaatatga caacagaaaa tcttaaagca gcattggaat
    15361 acgcagtaga actaaatgag catggtttgg aaattttaac agctgcagat ggaacagagt
    15421 attatgatgc caacaaattc aacctcaaag aacttgaccc taaacgctat cctaaaactc
    15481 tggagctatc aaccttgaca agccttgttg actatctcaa aacagaccta aacaatttga
    15541 aaaaccaacg cttgattgta gcagttgaga aaaatgatga ggtttgtgtg tggtctgaaa
    15601 atgatgagtt agaacgtcgc acattacttg ttgatgttaa ggcacgcatc ccagagttat
    15661 cttttggccg tttcctatca tcggaacagt tcaatatcat gttgcaatca aactttattg
    15721 acgataacga tcgtggcaca ttgctagaat ttgctagcgc attgaaaatt gagaatgggg
    15781 ctgaaattga agataatgga gtatctcaag tagcaacagt taaaacaggg gtggcaagcc
    15841 ttgctaaagg caaagcacct aatccggtta cattgcgccc atatcgtaca tttagcgagg
    15901 ttgagcaacc ggcaagccta tttgtcttta ggattgataa gcaagccaat atggctttat
    15961 ttgaggcaga tggtaagcgt tgggtagctg atgcagtagg aaacattgca gcctatctaa
    16021 aagagcagct agcagaccaa aaacttatca cagtattagc ataagaaagg ggaaattaaa
    16081 atgagtgatt acaaacaacg gatgattgaa gaatacaaac aattaaaaga gcgcaccaat
    16141 aagttaagtt tgatgattag taactattac gtaggaacac ttgattttaa actaaaatgt
    16201 cctattgagt tacttgaaac tcaacactat acaatgtgtg catatctcaa gatccttgaa
    16261 cagcgtgcag aaattgaaaa cattgagttt taaggtaatc aaaatgaaat ttgagttttc
    16321 tttgcctcgg aatactaagc taaaatctct aaacatggtt atcaatagta atgacagaca
    16381 acatcaaaca gataaggcta aagttactaa gcgcattaga gcttttgctt attggcatac
    16441 atcaatggac aaggataaag ggagggctgc ttttagcccc tctaaccctt gtgaggttac
    16501 agttacaatt tacagcccta ctaagtctaa attagatcca cctaacttgt atccgacagt
    16561 caaggctatc attgatggca tgactgatgc aggtatttgg acagatgata atcataaggt
    16621 tatcaaaaag ttatcctttg tttatggtgg cttaagtgag gaaaaagggc attatagatt
    16681 agagtttgat atagaggagg tttaaagtga ttgaagttaa tataaaattc gataattttg
    16741 aagcgcatgg cttttaccaa gatgatacta aactaggaaa aattagagat gcaatcatat
    16801 ctcaaatgaa taatgggcat gtggttattt taggggaaga tagaagtatt ctattaaatc
    16861 ctaaagttat taaatgtgta caatttgagg ttgtagaaga tgaccagatc taatcgtttt
    16921 ttgaccttta gagaatctga gttattttga ggaggtggag tgatggaaga gttaaagaaa
    16981 aaagttaatg aagtatacaa ctggacggta gaagacggga agccgcaacc tcccaagcaa
    17041 gatttaccac aagcggtgaa agaccgagcg gactattttt gggaaatggc agaagatggt
    17101 atgacgttta tgggagcgat ggaatgcatc ttcgctgatg aaaagcctac agactatgat
    17161 ttgggagcta ctaaggattg gttgccaaaa tctaaggagt ttgatgattg gattggctat
    17221 gcgccaagca tggctcaggt agttattgca gtttatttga tttatagagg aaactaagat
    17281 gaatattaag gcattgatta agaagtatga agaattgtgg aatgaacaca gcccttttta
    17341 tgaacctgta ccttatactt caatggttga actttttttg aaagagttga aacaactaga
    17401 cgaaccagaa aaagtcaaag ttccgcagtt tatggcggat tggattgatt atttcaaaaa
    17461 aaatggtgac tgggatttgt ttcaagcgat ggattatttg tttggaaaaa aagaaataag
    17521 ggaatggctt gagtataaaa acaaccaaga cctcttcgct cgtgcttggc ttgacggcta
    17581 cgaggtcgag aaagagaagc ggtatttggt gactttaaaa aataggcagc ctttggtcaa
    17641 atcgcaatca gggagtactc tttattttag tcaagatata acagctagga attataaagg
    17701 tactcaaaaa gaactagaag acgcaaagtt cggctgggta tttgattgcc cagggattga
    17761 gattgaggag gtgaagtaat gacacaaaca cttgaagaag ggatgaagaa tcaaagtaaa
    17821 tgcataaaaa tacctatgga aatcagaccg tttgatatag ggtatcgaat agtgaatcaa
    17881 catggaaatc cgcttgcttt aaaaaacgga gcaagtatat tcgatttacc ttcgctagct
    17941 gaaaaagcta ttaagaaaga gtttagtaaa gatgacccag attttgatat tgaaaaacat
    18001 ttcgttgaag aggttgctat tgtcaattta agtaaatttc atagttattt tgaggaggtg
    18061 atacatgact gatgacgaag aaaaaaatag agcgcttgtc agttatccat cgcagggaaa
    18121 tcaattggct aaagtggtat tttttgaggg ataagaaaaa tccaaagaga accattttgg
    18181 agcaaaagat tatagtttct catatcaaaa ctgataggct tgaagctaag tttttaagca
    18241 acttaaaaaa atcaactgaa gattttatag ataagtctga tcctaaatat ttgcgggcaa
    18301 taaaagaggt ttatgtttac gaaaacatga atgtcattgg agcttgtcaa aaaatactat
    18361 tttatagtcc gactcaagcc tatgtattac ttaatgcgtg gtttaacgat tattttcgtg
    18421 cgacttacac agaattacta gaaaacgcca tcttagataa ataaccgtaa aaaatccaaa
    18481 gcttatgtat ctataatcaa gatatataag ctttttcgaa aggagagata tggagatgtt
    18541 acagattgaa tatgtagata taaaatccat taaaccatat cacaaaaacg ctaggcataa
    18601 tgacggagag gcaacagaga aagttgctgc atccataaaa gcttttggtt ttcagcaacc
    18661 tatcttagta gatgataata acatcattat tacaggacat actaggctaa aggctgctct
    18721 ttctttaggt atagacacaa tacctatcgc tcacgctgta aacctcacag atgagcagat
    18781 aaaagcttat agactagcag ataatcgagt tgctgagtat tcaacgtggg actcagaatt
    18841 attaaatatt gagctttctc aatttgaaac aatagatatg gctcagtttg gttttgagtt
    18901 atcagttaca gggttcaact ttggtaacga ggaggagcag caagaggaaa ctgaaaacga
    18961 ggaggaagat gctgaggatt ttcacagaga cacaactata aatcagtaca atctttttca
    19021 ttatgacgat acaagggttg agggttttta taacatgcct aaaatcgagg gcgtggatca
    19081 tattcctaaa gattttcaag gctttaatta tgttttaaat aaaccagatt acagctcatg
    19141 cgtgcatttt ttcctagatg attatcaatt tgaaagaata tggcaaagac cagactttta
    19201 cattgaaaag ctgctagaat ttgatagcgc cttagctccg gattttagct tatatcttga
    19261 tatgcctatc gctatgcaag tatggaacat ttacaggtca aggctgatag gtcagattat
    19321 gcaagattac ggccttacag ttatccctac tgtatcgtgg gctagtgagg aaagctttga
    19381 tttttgtttt gacggcttgc ctaaaaactc aacgctagca atcagtacaa taggcgtaaa
    19441 gcaaaacaaa gagcagtttg aggtatggaa aaatggagtt actgagatga taaaacggtt
    19501 gactccaaaa agaattgtag tatatggcgg aaaagtggaa tacgattata aagatataga
    19561 ggttgtatat tttgaaaatg caacaacgga aaggatgaaa gaaagtggca caaaaactaa
    19621 ctaaactaaa agatattttt aaacatgttt caagtattga tctaggtaaa gagattttat
    19681 ttgaagatct tgagctttac aataaagaaa cagaaacaag caaacaatac caatctatcg
    19741 aggaggcaga aaatgaccta tctttgatgg aaaaagtaaa taaaatcaat ttcactctag
    19801 gcggtggacg tggtgcaaat tttgagaaag ggaaagacgg taagtatccg ggttttagag
    19861 gtgctggtgg tgcaagagat agtgggagct caaaagcctt acatccagca tctttaaaca
    19921 atcaagggcg cttttcaagt gttgagggaa ctatccagga atttattaaa aaacacggtg
    19981 gctctagaac agaatacagt acagcagttg actctcaagg ctttgctcat aattatgtac
    20041 acggtgggaa aaacagcgta caaattttgc ctatctctgg tggatttaca gcaatacata
    20101 accatccgaa tggcagcaat ttctcaagta cagatttaca tagctttgca gcattaaaag
    20161 gtatgaatac actagttgca acgaatagct ctaaagcgta tcgaattaca aaaggggcta
    20221 actttgatgc taaaggcttt gataaagctg tgagcaagtc acgttttact acaaaagatt
    20281 acaataaagg agctgaccta tggctcaaga aaaacgctaa gaaatacggg tacacttact
    20341 catacgagta aaagaaaaga ggctaaggta tgggtggtag aggagcaaaa ttaaacttgt
    20401 caacaacgaa aatgacaact caaaatatag agacttgatt aacaaaatcg aaaagttatt
    20461 aggaatagcg taaaacatcc ccttttttaa catatacaat gaaatcataa gtataaaatg
    20521 cttgtgattt ttttgtttga aaggagggtg gaaattgcct agagatggaa ctaaaaattt
    20581 aaaaccagtt acagaacgaa ccaaagatga agcaagagct attagctcaa aaggaggtaa
    20641 agcatctggc atagcaagaa gaaaaaaagc tgatctaaaa aaagcatttg aaatcctctt
    20701 atctttggat gtgacggata gtaaaatcaa gaaacaactt gaggagatgg gtatggctgg
    20761 caataacgag gctttgctag cctttgcaac ctttcagcaa gctgtaaaag gcaatcagaa
    20821 agcgactgag aacataatca agctgacaaa tactaaagat aaatacgata tacaagaaca
    20881 gaaagagcgt attaaagcac tcaaatatga aaatagagag cgtgctgaag ctgagaaagg
    20941 ctcaagtgaa actatcgaga tagtggatgc atgggctgaa gatgtgaggg gggcaacgga
    21001 tgacctttaa tgtccagaag aacatcaacc ctcatttcaa atctgtttgg atttctagct
    21061 taccttataa tgttttgaaa ggtgggcgta actcttttaa atcatcggtt attgtactta
    21121 aactagcgta tatgatgata aggtatatta tcgctggaga ggcggccaat atcgttgtta
    21181 tccgtaaggt ggccaatact attagagaca gtgttttcaa taaagtttgg tgggcattga
    21241 acctttttgg tatagctgag cagttcacaa aaacagttag cccgtttaaa atcgtacaca
    21301 aaacgaccgg ctcaacattt tacttttacg gacaagatga ctttcaaaaa ctcaaatcaa
    21361 acgacattgg aaatatcata gcggtttggt atgaagaggc tgctgaattt aatgaccaag
    21421 aggactttga ccaatcaaac gtgacgttca tgaggcagaa acacccacgc gccaagtttg
    21481 tacaattctt ttggagttac aatccaccta gaaatccata tagttggatc aatgaatggt
    21541 ttgagagcat caaaacgaat aagaactatt tagctcactc aagcacctat cttgatgatg
    21601 aactcggatt cgttactgag cagatgctag aagatataga gcgtatcaaa gagaatgact
    21661 acgattatta cagatactta tatctaggtg aggcagtggg attaggtaac aacgtgtata
    21721 acatgagtat gtttcatgct attgatgctt tgcctagcga tgataagctg attggcatat
    21781 catttgcgct agatggcgga catcaacagt cagcaaccgc ttgttgcgct tttggaataa
    21841 cagctaaagg taaggttata ttactagata cttggtatta ttcaccagct ggacaagtgg
    21901 taaagaaagc gcctagtcag ttatctaaag agatatatgc ttatatgcga tcagttattg
    21961 agaagtacag agtacaagcc ttgcaataca caatagatag tgctgaggga gcgttaagaa
    22021 accagatgtt tcttgacttt ggtttgaaat ggcatccagt cgctaaactt agaaaagtga
    22081 ctatgattga cagttttcaa tctttgcttg ctcaaggtcg cttttactat ctcaacaccg
    22141 aaaacaacaa gatatttatt gaagaacaca agatgtatcg ttgggatgaa aagactatca
    22201 aatctgataa tcctagcgtt atcaaagaag atgaccatac atgcgacaca acacagtatt
    22261 ttgtgttaga caatgcaaaa ttgctcggtt tgcgtgttgg taacgtttag aggaggacga
    22321 tcatgagcct atttcaaaaa gtaaaagact tttttagtcg agggaggtat tacatgcaga
    22381 catcaaatct taatagtatt ttggaacatc caaaaattgc agtgactcaa gaggagtatg
    22441 accggattaa gagaaatcta gtctactatc aatcaaaatg ggatgatgtt cagtacaaga
    22501 atacggatgg agatattaaa tcccgtccaa tgaatcactt gccaattgca agaacagcat
    22561 cgaagaagat tgctagctta gtttacaatg aacaggcaac tatcacaaca aaaaacgaaa
    22621 ttttacagaa atttttggat gacatgctaa ctaacgaccg attcaataag aattttgagc
    22681 ggtatctaga aagctgtttg gcacttggtg gcctagctat gcgcccttat attgatgggg
    22741 ataaggtcag agtggcattt attcaagcgc ctgtgttctt tccactagaa agcaacacac
    22801 aagatgtttc aagtgctgca atccttacta agactatcaa atctgagggg cgtaagaacg
    22861 tttactatac ccttgttgaa tttcacgaat gggtaacagc agacggacaa gaaacaggta
    22921 gcacaaacga taaaaagtat tatcgtatta caaatgaact ttataggtca gatgtgaatg
    22981 atgtgttagg tcaacgtgtg aacttgagtg aactagacaa gtacaaaaat ttagagcctg
    23041 taacagtctt tgaaaaccta tcaagacctc tatttactta tctaaaaact ccaggtatga
    23101 ataacaaaga catcaacagc cctcttggat tgtctatctt tgataacgca aagacgacta
    23161 ttgacttcat caatcgttct tacgatgaat ttatgtggga agtgaggatg ggacaaagac
    23221 gagttattgt gcccgaacat ctaacacaaa gacaatatca acgtccagat ggaacaatag
    23281 attttagacc acggtttgat gttgagcaga atgtttatat gcaaattggc ggctctagca
    23341 tggatgccgg gggcattaca gaccttacct caccaattcg agcaaatgat tatattttgg
    23401 cgatttcaga gggattgaaa ctctttgaaa tgcagattgg tgtatcaagt ggcatgttta
    23461 cattcgatgg tcaaggaatg aaaaccgcaa cagaaattgt cagcgagaac tcagacactt
    23521 atcagatgcg aagtagtatt gtcgcacttg ttgaacaatc tatcaaggag ctttgtgttt
    23581 caatgtgtga gctcggtaag gcggtagggg tttatagcgg agaaattcca gaacttgatg
    23641 atatttcagt taatttggat gatggtgtat ttactgatag gcatgcagaa cttgattatt
    23701 gggctaaaat ggtagccgca ggattctcaa ccaaaaaacg ggcaattggt aagacattaa
    23761 atatttctgg tgttgaggca gaaaaagaac tcaatgctat caatagtgag ttgctaccta
    23821 tgaatgatgc cgaacttgct atttatggta tgcatgacca aaacgaggag gaagcagatg
    23881 acaaaggtta aattcggagt tactagtgtt gactactcag caagcattga agatacgcca
    23941 acaataaaac taggtttaat aattagaggg agcgggagac tagatgcctc ttcagttatt
    24001 aaaaaactaa tcaaggatgt ttctgaacta gaatacgaat tagaagaata aactggtcaa
    24061 ttggccaatt ttctttcaag agagggcttt tgaatgaaaa aaaagagaaa acagctcacg
    24121 tttaacgacc aacaatttcc tttgcaaatg caaggcgttg gggatattta cgaaaaatta
    24181 cagattgata tctttgaccg tatgataaaa cgcttaaaag agcgtgggtc tattgattta
    24241 atgagaaacc cttatatctg gcagttagag aaactaaatg atatgcacat gctcaatgaa
    24301 cagaatctaa agcttatttc agagcgtaca ggaattgctg aaagattgtt gcgtgatgta
    24361 attgagaatg aaggtttgaa agtctataag gacactaaac agcaacttga agaagatttg
    24421 aataaaatac ctgagggaga gatttcaaat ggcgtaacgg acagcttaga ggcttattcg
    24481 aggcaagcag ttagtgattt aaaccttatc aatacaacat tacctaagag cttgcaagta
    24541 gcttataaat cgattgtgga ggagacagtc gcacaggtag ttgcaggaac taaaacaagc
    24601 gatgttgctt tgcatgatac catcatgaaa tggcagaaga acgcttttac gggctttgtc
    24661 gataaaggcg ggaggcattg gaaagctgat agctatgcga gggctattat caagagcaca
    24721 acatacaaag tttataacga aatgcgtact agacctgctg aggagttagg agtagatact
    24781 ttttactatt cgatgaaagc aatggctaga ccagcttgta gtccgttaca agggcagata
    24841 gttacaaaag ggactggtag ggagatagat gggataacta tctattcatt attggattat
    24901 gggtatggaa cagcagcagg atgtttagga atccattgtg gtcattatct gacaccgttt
    24961 attgttggag ttcatgagtt accgaactta ccagactatc tgaagaatct aacaccagaa
    25021 caagctgaag aaaatgcacg cattgaagca ggtcaaagag gccttgagag acttatcaag
    25081 acacataaag agcggttgca ttacgctcat accttgcaag atgacaagat gatacaagct
    25141 gagcgtttga aagttagagg gtatcaaact aagatccgta acttgataaa tcagcatgat
    25201 ttcttaacaa gagattacag acgagagaaa ttatatattt cataaaggat ttgtgtttca
    25261 caagtccttt tttgtgttta aaaccgtaaa aaatccctat ccatcaaagg tatattgaga
    25321 gagtaaataa tattttgctt taggtgggag ttatccacct aaaaaagaac taggagggta
    25381 caaatggcat ttacaactga agaactactc aatcttgggt tgacagaaga acaggctaag
    25441 tcagtctttg ctttgcgagg aaaagagctg aatgaggaca aatcagcctt agaaactatc
    25501 aaacaagagc gagatagtct caaatcacag ttgcaaaaag cagaggagca agttgaacac
    25561 ttgaaatcac ttgagaatat cagcgctgaa caaaaagatg cgattgataa attgcaagct
    25621 gaatatgaca agtataaaaa cgaagctgca gctgaacttg cacagacaaa aaaggttagt
    25681 gctatcagtc tagctctgaa agatacaaat gctttcaatc cagacaaatt gatgaaattc
    25741 attgatgttg atgctatcca gttagacgac aacgggaaac ctcagattga tgaagtaatc
    25801 aacggtttaa aagaaagtga tccatatctg ttcaaagctg aagaaagtaa gcctagcccc
    25861 aatattttac ctcaaggtaa tccggcagga gagggtacaa gtgatgttga tccgttccaa
    25921 gcgattattg acgggtatgg caaataacag aaaggagatt acaaatgcca agtaatcaaa
    25981 acaacgcagt gcgccgctat gagaaacaat atgcgggcat tcttgagaca gtttttggag
    26041 tgcgggcagc attttcaaac gctctagcac ctattcagat tttggatggg gtacaagaaa
    26101 actctacggc tttctcagtt aaaacaaaca acacaccagt tgtaatcagt gagtacaaaa
    26161 ccggtgaaaa tgatggtggt tttggtgata actcaggggc tcagtcacgc tttggtggtt
    26221 tgacagaagt taaatatgaa aatacagatg tcaactatga ctataccctt acaatccatg
    26281 aggggcttga ccgttacaca gtaaacaatg atcttaacgc tgctgttgcc gaccgcttga
    26341 agttgcaatc cgaggcacaa actcgaacag tgaacaagcg aattggtaaa tacttgtctg
    26401 acaacgctac taagacggaa gcccttgctg attttacaga tgacaaagta aaagctttat
    26461 tcaataagtt gtcggctttt tacacaaaca acgaagttac agcgccgatt actgtttact
    26521 tgcgttctga attttacaac gccatcgtag atatggcatc agttacaagc gccaaagggg
    26581 caactatctc ccttgatgaa aacgggctac caaaatataa gggctttacc ttggaagaaa
    26641 cgccagcgca atactttgag acaggagtta tcgctatctt ctcaccaaac ggtattatca
    26701 ttccgtttgt tggtatctca acagcccgtg taattgagac tgaaaacttt gatggtgtga
    26761 aattgcaagc tgctgctaag ggtggtactt acactcttga tgacaataag aaagcaattt
    26821 acaaagttac aggaactatt gtataggagg tagaacatgg cactttacaa agcaacaaaa
    26881 aatcttttct ttgagcaact caacatggat gtgattgtca atgacattat tgaacttgat
    26941 gaagattatg ctaaagaagt caacaagaaa ctaaaaaatg cttttccaga tgtgaaaaat
    27001 gttttagaac ttgttgacaa aaatggaacg cttgaaccag aagatgcccc atctgtagaa
    27061 gatgcatctc aggcaactgt tgaagattaa ataaggggtg acaacaccct ttatttttaa
    27121 gggaggttac acatgactta tttgacacaa gaggagttcg atgagttagg ttttgatgaa
    27181 gttacagact ttgaaaaatt ggcaaaacag gcaaagatag cgattgacct atatactaac
    27241 ggtatttatc agaaagacat tgattttgaa aaagaaattg cctatcgcaa atctgctgta
    27301 cagcttgcta tggcattcca aatagcctat ctcgatgcct ctggtattat gtcagccgat
    27361 gacaaacagc tagccaatag tgtctctatt ggccgtacat caatctctta tagcacctca
    27421 caaagcacat cagcaggtca gcgatttaat ttgtctatgg atgctgaaaa tgctttgaga
    27481 caagccggct ttagcctagt tgttggagtt gcctatgatc gataagcggt tattaaaagg
    27541 gattgacaag cgtttgttaa aggatgtcct aaccataaaa aaagtagctg ataaaaacga
    27601 ttatggggat gaagtatatt cagaaccgtt gactattaaa aatgtacgtt ttgatagatc
    27661 agtggggaga tctggtaatc gtaactcaaa aactggtaca ggaaattcaa aatcaaggca
    27721 aaaacaaggg gttatatacc tctatccctc gctatctttt gtgacagttg ataacagttg
    27781 gatgggtgca aaagtaaacg atgggatagg agattataca attaatggat ttcaaactaa
    27841 ctattatgat ggtgagatat tcagtcaaga aattgaggtg atctaatgag tatcgccatt
    27901 aaagttgact tgcagaaagc taaacagaaa ctttcgaacg aatccatgac aagaggaaag
    27961 attgcagtcg ctagcaaaat cttgctagac aatgagcaat atatcccctt gaggggtgga
    28021 gagttgagag cttctggccg aatcgttgga caaggtgatg ctgttgtcta tggaacagtt
    28081 tatgctagag cgcaatttta cggagcaaac ggcattgtca cctttaggag atataccact
    28141 ccaggtacag gaaaacgatg ggatcaagtt gctactagta aacatgctga agaatgggct
    28201 agagcttttg tgaaaggaat ggggctttga tgcgagagaa tgactttcaa aatgtacttt
    28261 taaagcatat caagacttta aatttaccag ttgaaccacg ctttgattac tttgaggatg
    28321 acaaagatga tctggttatc aatcagatac caggcgggaa agtggataga gagtatatgg
    28381 atggcacaca agaagtttct ttgccgtttg aaatcgccgt aaaggcaaaa aagaactcag
    28441 tagccaatga cactatttgg ttagtcacct cagaactagc aaagatagac ttagttttac
    28501 caagtgacaa taattcttat gaatatatgg gaatggaagt cagcaggcct gccatgaaag
    28561 gcaaggatga gcaaggctat tattattaca caattgaaat tgtggcgaaa atcgtaatag
    28621 agaggaacaa acaatgacaa gacaaaaaaa cgccctacgt ggccattttg tagctccata
    28681 caatggagga actgaaccat caacagaaga tacatggttg gaacttgcta aatggatctc
    28741 agacgtatca gatgatacag acgagaaaac agatgatcaa gcatactatg acggtgatgg
    28801 agttgaagaa acaaccgtgg tcagcgtaaa aggtgcttat acctttgagg gtacttacga
    28861 tccagacgat aaagcacagg ctcttattgc tgggatgaag tacaagacag gggatgaccg
    28921 taagctatgg cacaaggttg tttcttctga caggaagaaa caatgggtgg gagctgcaac
    28981 tgcaacagaa atcaaagcag gttctggcgc tgcctctgac tatgaggcgt ttggatgtaa
    29041 gctttcttac aactcaacgc caaaagagac tggtattggg taatagcttt tgataagggc
    29101 gggcattgag ccttgccctt tttaacaaca ggaaaaggag taaagacatg acagatattc
    29161 agattgaact aaaacgtaca ggatttccag taaaaatcgg agaagtagag ctatggtttg
    29221 atacaagtca agagagctta atgcgctttt atgacatgga agaagaacta aaacgtcgcc
    29281 ttgtccaata tgaattagat gtggtatctg caaatatcaa taacaaaatt gagcgtgatg
    29341 gagtaactaa agaagtagtt gctggggcta ttgaattgga gaagaaacag cttgagattc
    29401 aatatgatct tatttttggc gacggtacat ttgacaagtt atattctata tatccagatt
    29461 ataacgccct aaataacgct ctagaacaga ccgcaatcat gttgcatgac aagttggaag
    29521 aagttgctga gcaacacaaa acggtggtga aagagcgtgc tagtcactat ttaaacaagg
    29581 gaaaagtcac tccaatcaag aacaacaaga aacaaaaaaa gaacaaaaag aaatagcagg
    29641 taaaaaatat gtctatgaaa ttaaatgatg ccttaatcac aaatttttct attgctgata
    29701 aagagtacga catagacctg tcttttaata aagttctaga tgtctttgaa atcctaaaag
    29761 aggatgaaat gacgcgtcta gaacaagctc agttgattgt ccatttgcta actggacaag
    29821 aattatacaa catcaaagag gttgtagatt gttggattta cataaaagaa cactttctag
    29881 ggatcgaaaa agaaactgtt cagtatgatc tgctaggcaa tcccatgcca aaggcaaaag
    29941 gtgaagaaga acaagaaaaa ttgattgatt ttgaacaaga tgcagaatac atttacgcta
    30001 gttttttaca ggcttatggc atcaacctct taaagtctca aaataagttg acatggacag
    30061 aatttaaagc gcttttgaat gctttgccag acaatacaat catgcaacag attatagaaa
    30121 tccgagcatg gaaaccagaa tatggtgggg ataagaataa aatgcgcaaa ttacaagcta
    30181 aatatagttt aggaaaggag ggagaagata atgtctgatg gaaaagtgac catcgttgtc
    30241 gatgtggatg gtaataaagt caaggttcta aacgatgagt tagataaaac ggcacagaaa
    30301 ggtgatagag ggagcagttc cctaaagaaa tttgcggtag gcagtgcagt tttccaactt
    30361 gccgctaaag gtgctgaact tttgggagag gctttaggag gcgctattca gcgttttgac
    30421 acgttagaaa gttatccaag agtgatgcaa gctatggggc atagtacaga agatgtcacg
    30481 cgctcaacta agaaactagc ggcaggtatt gagggtttgc ctacgacttt aaatgaagtg
    30541 gtaggcacag ctcaacgcct tacctcgatt actggcgata taaacaaatc aacagattta
    30601 acacttgctc ttaataatgc ctttcttgcc tctggatctt ctagtgctga tgcaagccgt
    30661 ggtttacatc agttcagtca gatgttatca gctggtaagg ttgacatgca aagttggaaa
    30721 acgttacagg aaaccatgcc ttatgctttg caaaagactg ctgaatcatt cggttttgct
    30781 ggccaatctg ctcagaatga tttctattct gcattaaaag aggggcgtat cactttcaac
    30841 caattttcaa gaaaattggt tgaattgaat ggtggcgttg gtggttttgc agaacttgct
    30901 aaaactaaca gtaaagggat ccagacatct tttgggaact taaagaatgc ggttgttaaa
    30961 ggtgtagcta atactatcaa ggctcttgac gatttaacaa aggcagcaac aggtaagacg
    31021 attgctgaga acttcgatgc attgaaagta atcatcaatg cggcttttgg tgttattgtc
    31081 aacgtaatta aagctagcac acctgttttt cagactttgt ttagtatttt gagtactgga
    31141 gcttctgtaa tctcattttt gacaccggct attatcggtt tagttgctgc tttggtaact
    31201 atgcgtgcca tcaatcaagc ggtaaaaacg actaaggact tgataagcgc gtggaaaaca
    31261 ttcaaaacaa cagccacagg agcgattcag atcatcaatc taatgacagc tgcccaagct
    31321 acttgtggct cagtaacaaa ggctcaaatg gttgctaact tggccaataa cggagctttg
    31381 acagcatcca atttgcttta tggggttcta actggctcta tcagcttaca gactgctgct
    31441 actattgctg cgactgctgc aactaccgca tttaaagcag cactgaccgc tttaactggc
    31501 ccgattggtt tggttgttac tgggattggt ttggttgtgg gagtatgtgt gactttgtgg
    31561 caatggctaa ctgccgagag tgaggagacc aaacgcctca aatcagaaca agaggagtta
    31621 gtcaagagta cggatcaatt aacggattct gttaaacaaa gcgcaaaaga acgtcaaaaa
    31681 aatcttgagt ctgtaaaagg taatacagaa tcttaccaaa aattggctga cgaaattgtc
    31741 cagttatcac aaaagacaaa taagacagca gcagacaaga aaaatcttaa gaaaaagatt
    31801 gatgctttga atgcctcagt tagcggttta aatctagcct atgataagaa ctctgattct
    31861 ttgtctcata acagtgacca aatcaaagct cgtatctcag cgatggaggc agaatcaaca
    31921 tgggagacat cccagaagaa cctgcttgat atcgaacaaa agcgtgctga aattggcgaa
    31981 cagctaaagc agatagctga acaacgcaaa aaatggaatg aagaatccaa tgttagcgat
    32041 agtgtccgta aagaaagact gcaagaactc aacgacaagg aaactgagct aaaaaatact
    32101 cagacagaat tgcaaactga gtacgaaaaa acgtctcaag ttcaacaggc ggcatctgaa
    32161 gcgatggctg ctgctgccga aaatggttca aatagacaag ttgtagcata cgaaaatatg
    32221 tctaaatctc aacaaaaagc aatagacgat atgcgtacta agtacaatga attacttgag
    32281 acaactacga acatgtttga acaaatcaag tataagtctg ctattagtgt cgatgaaatg
    32341 attgccaacc tccaaaaaaa ccaagaggcg gttaataatt gggcaacaaa cctcaataca
    32401 ttggccgaac gtggggtaaa cgaggggatt ttagctaaat tacaagcgat ggggcctcaa
    32461 ggtgggttgt acgttcaaga actcgttaat gcatcagacg aaaaattggc aacattgaac
    32521 gaagtcttta ctcaaggtgg tgagtcagct atgaatggct taactgctgg tatggatacg
    32581 ggtgctttgg gtatcacaga caaaatcaag ggtattgtac aaagtcaagt ttcaagctta
    32641 caagaggaaa ttgcagctgc tgacttttct agtttggggc aagaaatccc caacggggtc
    32701 agtcaaggga tagaacaagg agcttctact gccggagaat cttctaaaaa catggctaat
    32761 gatataaaag aatcctttac gagcgaaatg gatattaatt ccccatctcg tgttttcaat
    32821 gagtatggtg gttttatcac tactggttta gctgaggggg tagataaagg taccaatcaa
    32881 cctgtatcat ctgttactaa tttagccaat caaattaaga aaccatttga tagtctgcag
    32941 agtgatttca cgtacattgg tgaaatggcg atgtctggtc ttaatgcagg gctttggagt
    33001 ggctctggtt ctgttatggc aacagctaat tcaattgctg aaagggtaaa agcgaccatc
    33061 aagagcgcac tagatattca ctcgccatct agagcaatgc gtgatgaagt cggacgtttc
    33121 attcctcaag gtatcgctgt tggtattgaa gcagatgcag gggttgttga aaaatcaatg
    33181 ttgcgattaa aagaaagcat gatgattgat actagaccag aaattgcact tggcttaaac
    33241 aagaaactag gtgctcaagt gactgttaaa caaagtagta agcagacaat agctgaaaaa
    33301 atcaaagtta ctatggacaa gtctagcgaa ctactcgaaa aagccctgga tgtagctgag
    33361 acggccgtta gacgaccaaa tgaaatgtac ttaaacgatg gtactttagt cgccagaaca
    33421 ggcgataaat ttgctaaata tcaatcggaa caactaagac gagataatag gatgaaaggg
    33481 gtattgtcat gacaaagata atgactttca acggagttga tatgtctaaa ttctttcgta
    33541 taacagatat tatccgccct atcgggaaca agaggagcgt atcaactgat aacgctccct
    33601 tattgggcgt gaatatccaa caggttaaga ttggagaaaa agagcatatc ataaaatttg
    33661 acatcaaaac cacaaatgca attgagatgg aacaattaaa gcatgatttg gcaggcattc
    33721 taaacgtttt agagccagta aagattactt atggcgatga gccagacaaa tactatatgg
    33781 ggttgccggt agatgagatt actccagaaa atttgacaag atggttccag cgctcagagt
    33841 taaaaataat aattcctgat ggcgtggctc acagcacgac tttaaaaaat tttgatatcg
    33901 atacaaatga aacaagcgca ccggatagga tagtatttaa tttaacaaat acaggaacag
    33961 agccagctta tccaattatt agaattaaac acaactcaga gaatggatat attggagttg
    34021 ttaacaacag agcggcgttt gagttaggaa atcgtgaaga ggctgatact gaaaaataca
    34081 gagactctga aacattgata gattatagag ggactaatat tctaaaagga tttcaaaatg
    34141 gcactaaagg agtagctgta acaaatgata ataaggagcg tcttgttggc actttgagta
    34201 caacaagtat gtgggggcgt aatcatatcg aattatcaaa ccgtggtaca gttgaaaaaa
    34261 atcgaaataa tgcacaaagt ttgacatggg ctattcctgt tgatagtagt ggagaagttg
    34321 gttcattgaa tgactatctg ctttggagac aagtttttat ggcagcagtc gctaatcaat
    34381 atggtttcat aaaggttact gtatcggata cagacggcaa tttcttgtat ggggtggaaa
    34441 cttacaaacg ctatcagaca cttgattgtg agtatagttt tttcaccact gacggcaaag
    34501 gtggatacaa gtttatcaaa tggtggtatt ttactgggac aggggctcaa gtaggcaaac
    34561 ttgatccatt tagcgcggaa aagggctggt cagagttaaa aagaaacgat gatagagttc
    34621 aagtgttttt tgatggctct cattatgact ttattattcc ggagataaaa gacaaaaaat
    34681 cagcaaaaat ccatatcacg cttggagcac tcagagactg gcctcttgta tcacatatgt
    34741 atgttgatga gttcatgtat agaaaagact ttgtgacaaa gagtagagat attcctaatc
    34801 gctatccaat aggttcaaat gttgtaatca acagtgagga cgatagtgtg tatattgacg
    34861 ggatatctaa agtaagcgaa gttgtagacg gttcacattg gccagcaatt cctccaggaa
    34921 aatctcaact agagttgtat ttttcacgtt ttgttaagaa aaaaccaact gtaacaatcg
    34981 aatttgaaga aaggtggata taagatgctt ttgacaatcc atgatgcaaa tttacaaaag
    35041 gtagcattta ttgataacga aaaacaaggt acgttaaatt attacgatga tacttggaca
    35101 agaagtcttg caacaggttc gtcaacgttt gagtttacgg tatttaaaaa ggctgtaaag
    35161 tctgatttac ctcttgctaa agcctatcat catttgaatg agcatgcatt tgtctcattt
    35221 aagtacaagg gtaaaagctt tgtgtttaat atcatgattg ttgaagaaaa tgagcagaca
    35281 atcaaatgtt attgtgaaaa tctcaatctt gagttaatca atgagcttgc gaacccttat
    35341 aaatctaaca aagcgatgac tttcaaagag tattgtgagg cgatggatct tttaaattat
    35401 actcaccttt ctattggtat caatgaaata tcagattata agcgtactct ggaatgggag
    35461 gggcaagaaa ccaaactagc ccgtctatta agcctagcca aacgatttga tgctgagatt
    35521 gaatttgata cacagttaaa tgctgatagc actatcaaaa agtttagtgt taatgtttat
    35581 catgaaaacg atgacaacca tcaaggggtg ggacgtgtaa gaaatgatgt cattgttaaa
    35641 tacggaaaaa acatccactc tattacaaga aaagtggata agactggtat tttcaataca
    35701 atcagaccga ctggtaaaat gccaacggtt gaagaagaac cgagcggaga taagggctcc
    35761 aaaagcgaaa ctgtaaaaaa tgcagatggt tcaacgacga aaaccacaat ctctacagcc
    35821 tcagatggga ctaagagcaa aactattgtc cacactaaag ttacaaagtt agcggacaag
    35881 acacggatca caacgaccac aacgactcgt tctgatggtt ccatagaaca aactgttaca
    35941 accagcaaaa aaggcggagc atcaacgtct gaaacaaaag tcttgaaaaa accaaatcca
    36001 aaagaaaaaa caaatacaac tgaggatgtt ttgacgattg agggattgga tgaatgggaa
    36061 gtaaagaacg agaaagggat agttgaattt tatcaaagag ggcaagcact gtatgcgcct
    36121 atttcaatgc aactatatcc ctcaaccttt actcattcaa caggggagct tgaccagtgg
    36181 acaagaaaag attttcattt tgaaacagat gagccaaacg agttaagacg tttaggttat
    36241 ctcaaattga aaaagtattg ttatccagct atcacttatg aagttgatgg ctttgtcgat
    36301 gctgatattg gagatactgt taaagtccat gatgacggtt ttgcccctct attgatgatt
    36361 caagcacggg ttactgatca aaaaatcagt ttcacaaatc cattgagaaa taagacaata
    36421 tttgacaatt tcaaggcact tgaaaacaaa ctatcagctg atatccagtc agcctttgag
    36481 agattgtttg aagctgctaa accatatact atcaaattgt caacggacaa tggtgttatc
    36541 tttaaaaatc agatcggcca gagtctagta accccaacct tatacaaggg aggaaaacca
    36601 gtcgttgttg gtgttacttg gcgatgggca cttgatggag aagtaacaac agggatgact
    36661 tacttagtta gaggctcaaa tgtaactgat acagttactc tgacagttgc agcttacatt
    36721 ggaaataaag aggttgctgt tgatgagata tcgcttgtta atgttgctga tggaaaactt
    36781 ggtacacctg gaactccagg gcgagatggc cgtactcctt atgtccatac agcatgggct
    36841 aataatgcaa caggaacaga tggatttagt cttgatagct caatcaataa actctatatt
    36901 ggtatttata cagactttga accaaacgat agcaccgacc ctaaaaaata caagtgggct
    36961 aaagtaaaag gagacaaggg agaaaaaggc gataaaggag aaccaggaca acgtggttta
    37021 caaggcttgc aaggcgcacg aggtgaacaa ggtattcctg gacctagagg ggcagatggc
    37081 cgtactcaat acactcacat agcttacagc aatagcgctg atggaactaa ggatttttct
    37141 gtaagcgcct ctgatagagc ttatatcggt atgtatgttg attttaatag tgctgatagc
    37201 aatactccat ctgattacaa ttggacactt gtaaaaggat ctgatggcgc aaatggtgtg
    37261 gcaggta
//
LOCUS       DAVLXH010000016        36524 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00028199
            SAMN33607166-rid17955573.denovo.016, whole genome shotgun sequence.
ACCESSION   DAVLXH010000016 DAVLXH010000000
VERSION     DAVLXH010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607166
            Sequence Read Archive: SRR23725544
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 36524)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36524)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721421.1
            Genome Coverage       :: 115x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:42:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,210
            CDSs (total)                      :: 2,161
            Genes (coding)                    :: 2,023
            CDSs (with protein)               :: 2,023
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 73 of 138
            Pseudo Genes (incomplete)         :: 60 of 138
            Pseudo Genes (internal stop)      :: 40 of 138
            Pseudo Genes (multiple problems)  :: 31 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36524
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607166-rid17955573.denovo.016"
                     /strain="AUSMDU00028199"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1349"
     gene            complement(197..2086)
                     /locus_tag="VYO11_000884"
     CDS             complement(197..2086)
                     /locus_tag="VYO11_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2207 domain-containing protein"
                     /protein_id="HEV1595473.1"
                     /translation="MKKTFFLLMFGLFCLLPLSVFAIDFKINSYQGDLYIHADNTAEF
                     RQKIVYQFEEDFKGQIVGLGRAGKMPSGFDIDPHPKVQAAKNGAELADVTSEVTEEAD
                     GYTVRVYNPGQEDDIVEVDLVWNLKNLLFLYDDIAELNWQPLTDSSESIEKFEFHVRG
                     DKGAEKLFFHTGKLFRERTVEKSNLDYTIRLDNLPAKRGVELHAYWPRTDFASARDQG
                     LKGNRLEEFNKIEDSIVKEKDQSKQLLTWIFPSILSISLLLSICFYFIYRRKTAPSIK
                     YAKNHRLYEPPMELEPMVLSEAVYSTSLEEVSPLVKGAGKFTFDQLIQATLLDVIDRG
                     NVSIISEGDAVGLRLVKEDGLSSFEKDCLNLAFSGKKEETLSNLFADYKVSDSLYRRA
                     KVSDEKRIQARGLQLKSSFEEVLNQMQEGVRKRVSFWGLPDYYRPLTGLEKALQVGMG
                     VLTILPLFIGFGLFLYSLDVHGYLYLPLPILGFLGLVLSVFYYWKLRLDNRDGVLNEA
                     GAEVYYLWTSFENMLREIARLDKAELESIVVWNRLLVYATLFGYADKVSHLMKVHQIQ
                     VENPDINLYVAYGWHSMFYHSSAQMSHYASVANTASTYSVSSGSGSSGGGFSGGGGGG
                     SIGAF"
     gene            2225..3790
                     /locus_tag="VYO11_000885"
     CDS             2225..3790
                     /locus_tag="VYO11_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HEV1595474.1"
                     /translation="MRKIYLSIFTSLLLMLGLVNVAQADEYLRIGMEAAYAPFNWTQD
                     DDSNGAIKIDGTNQYANGYDVQIAKKIAKDLGKEPLVVKTKWEGLVPALTSGKIDMII
                     AGMSPTAERKQEIAFSSSYYTSEPVLLIKKDSAYASAKSLDDFNGAKITSQQGVYLYD
                     LIAQIPGAKKETAMGDFAQMRQALEAGVIDAYVSERPEALTAEAANSKFKMIQVEPGF
                     KTGEEDTAIAIGLRKNDNRISQINASIETISKDDQVALMDRMIKEQPAEATTTEETSS
                     SFFSQVAKILSENWQQLLRGAGITLLISIVGTIIGLIIGLAIGVFRTAPLSENKAIYG
                     LQKLVGWVLNVYIEIFRGTPMIVQSMVIYYGTAQAFGINLDRTLAAIFIVSINTGAYM
                     TEIVRGGILAVDKGQFEAATALGMTHNQTMRKIVLPQVVRNILPATGNEFVINIKDTS
                     VLNVISVVELYFSGNTVATQTYQYFQTFTIIAVIYFVLTFTVTRILRFIERRMDMDTY
                     TTGANQMQTEDLK"
     gene            3790..4530
                     /locus_tag="VYO11_000886"
     CDS             3790..4530
                     /locus_tag="VYO11_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV1595475.1"
                     /translation="MTQAILEIKHLKKSYGQNEVLKDISLTVHKGEVISIIGSSGSGK
                     STFLRSINLLETPTDGQILYHGQNVLEKGYDLTQYREKLGMVFQSFNLFENLNVLENT
                     IVAQTTVLKRERTEAEKIAKENLEKVGMGERYWQAKPKQLSGGQKQRVAIARALSMNP
                     DAILFDEPTSALDPEMVGEVLKIMQDLAQEGLTMIVVTHEMEFARDVSHRVIFMDKGV
                     IAEEGKPEDLFTNPKEDRTKEFLQRYLK"
     gene            complement(4639..4854)
                     /locus_tag="VYO11_000887"
     CDS             complement(4639..4854)
                     /locus_tag="VYO11_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1595476.1"
                     /translation="MAKSNFEKVESVVGWVRDKKITGYRISKETNAREMSIIALAQGR
                     AKVKNISFETALGLIDFYEKNYEKFED"
     gene            complement(5725..6975)
                     /gene="ilvA"
                     /locus_tag="VYO11_000888"
     CDS             complement(5725..6975)
                     /gene="ilvA"
                     /locus_tag="VYO11_000888"
                     /EC_number="4.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine ammonia-lyase IlvA"
                     /protein_id="HEV1595477.1"
                     /translation="MLSSKDIIKAHKVLNGVVVNTPLDYDHYLSEKYGAKIYLKKENA
                     QRVRSFKIRGAYYAISQLSKEERERGVVCASAGNHAQGVAYTCNEMKIPATIFMPITT
                     PQQKIGQVRFFGGDFVTIKLVGDTFDASAKAAQEFTVSENRTFIDPFDDAHVQAGQGT
                     VAYEILEEARKESIDFDAVLVPVGGGGLIAGVSTYIKETSPEIEVIGVEANGARSMKA
                     AFEAGGPVKLKEIDKFADGIAVQKVGQLTYEATRQHIQTLVGVDEGLISETLIDLYSK
                     QGIVAEPAGAASIASLEVLAEYIKGKTICCIISGGNNDINRMPEMEERALIYDGIKHY
                     FVVNFPQRPGALREFVNDILGPNDDITRFEYIKRASKGTGPVLIGIALADKHDYAGLI
                     RRMEGFDPAYINLNGNETLYNMLV"
     gene            complement(7025..7381)
                     /locus_tag="VYO11_000889"
     CDS             complement(7025..7381)
                     /locus_tag="VYO11_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001027901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HEV1595478.1"
                     /translation="MNITNLFSIKTGCDETDRQLQKLFFQLDLQLGELTDQLRKLDSN
                     FVPRSQFVDTLDLNDVEYKEILNYFIFHRNDSEESLVEWLYDWISTNRYELPKEFSIR
                     MAHKYHESVTEVFGDE"
     gene            complement(7619..7855)
                     /locus_tag="VYO11_000890"
     CDS             complement(7619..7855)
                     /locus_tag="VYO11_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1595479.1"
                     /translation="MLADQNKADWSYDENAVINIYDDANFEDGRLHMTFEQFFKLAQI
                     AREEGLEIHSPFERAGATKSARYIAKWILRNKKH"
     gene            complement(7962..8984)
                     /gene="ilvC"
                     /locus_tag="VYO11_000891"
     CDS             complement(7962..8984)
                     /gene="ilvC"
                     /locus_tag="VYO11_000891"
                     /EC_number="1.1.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HEV1595480.1"
                     /translation="MTVQMEYEKDVKVAALDGKKIAVIGYGSQGHAHAQNLRDSGRDV
                     IIGVRPGKSFDKAKEDGFDTYTVAEATKLADVIMILVPDEIQQELYEAEIAPNLEAGN
                     AVGFAHGFNIHFEFIKVPADVDVFMCAPKGPGHLVRRTYEEGFGVPALYAVYQDATGN
                     AKNIAMDWCKGVGAARVGLLETTYKEETEEDLFGEQAVLCGGLTALIEAGFEVLTEAG
                     YAPELAYFEVLHEMKLIVDLIYEGGFKKMRQSISNTAEYGDYVSGPRVITEQVKENMK
                     AVLADIQNGKFANDFVNDYKAGRPKLTAYREQAANLEIEKVGAELRKAMPFVGKNDDD
                     AFKIYN"
     gene            complement(9050..9526)
                     /gene="ilvN"
                     /locus_tag="VYO11_000892"
     CDS             complement(9050..9526)
                     /gene="ilvN"
                     /locus_tag="VYO11_000892"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002927678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase small subunit"
                     /protein_id="HEV1595481.1"
                     /translation="MRRMLTAKLQNRSGVLNRFTGVLSRRQVNIESISVGATEDPNVS
                     RITIIIDVASHDEVEQIIKQLNRQIDVIRIRDITDKPHLEREVILVKMSAPAEKRAEI
                     LAIIQPFRATVVDVAPSSITIQMTGNAEKSEALLRVIRPYGIRNIARTGATGFTRD"
     gene            complement(9519..11219)
                     /locus_tag="VYO11_000893"
     CDS             complement(9519..11219)
                     /locus_tag="VYO11_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase large subunit"
                     /protein_id="HEV1595482.1"
                     /translation="MEKISLESPKTGSDLVLETLRDLGVDTIFGYPGGAVLPFYDAIY
                     NFKGIRHILGRHEQGCLHEAEGYAKSTGKLGVAVVTSGPGATNAITGIADAMSDSVPL
                     LVFTGQVARAGIGKDAFQEADIVGITMPITKYNYQVRETADIPRIITEAVHIATTGRP
                     GPVVIDLPKDISALETDFIYLPEVNLPSYQPTLEPNDMQIKKILKQLSKAKKPVLLAG
                     GGISYAEAATELNEFAERYQIPVVTSLLGQGTIATSHPLFLGMGGMHGSFAANIAMTE
                     ADFMISIGSRFDDRLTGNPKTFAKNAKVAHIDIDPAEIGKIISADIPVVGDAKKALQM
                     LLAEPTVHNNTEKWIEKVTKDKNRVRSYDKKERVVQPQAVIERIGELTNGDAIVVTDV
                     GQHQMWTAQYYPYQNERQLVTSGGLGTMGFGIPAAIGAKIANPDKEVVLFVGDGGFQM
                     TNQELAILNIYKVPIKVVMLNNHSLGMVRQWQESFYEGRTSESVFDTLPDFQLMAQAY
                     GIKNYKFDNPETLAQDLEIITEDVPMLIEVDISRKEQVLPMVPAGKSNHEMLGVQFHA
                     "
     gene            complement(11420..13087)
                     /locus_tag="VYO11_000894"
     CDS             complement(11420..13087)
                     /locus_tag="VYO11_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HEV1595483.1"
                     /translation="MSKITTSLFQEMVQAASTRLNKQAEYVNSLNVFPVPDGDTGTNM
                     GMTIENGAKEVADKPASTVGEVASILAKGLLMGARGNSGVITSQLFRGFSQAIKDKDE
                     LTGQDLALAFQSGVEVAYKAVMKPVEGTILTVSRGAAIGAKKKAEQTDDTVEVMRAAL
                     EGAKTALAKTPDMLPVLKEVGVVDSGGQGLVFIYEGFLSALTGEYIASEDFVATPANM
                     SEMINVEHHKSVAGHVATEDITFGYCTEIMVALKQGPTYAKDFDYDEFRNYLDELGDS
                     LLVVNDDEIVKVHVHTEDPGLVMQEGLKYGSLVKVKVDNMRNQHEAQVEKEATQVIKS
                     AEEKEYALIAVVAGKGLTDIFCSQGVDYVIEGGQTMNPSTEDFIKAVEQVNARNIIFL
                     PNNKNIFMAAQSAAEVLEQPAVVVEARTLPQGMTSLLAFDPSKSIEENQERMTAALSD
                     VVSGSVTTAVRDTTIDGLEIHENDNLGMVDGKILVSNPDMHQTLTETLKHMLDEDSEI
                     VTFYVGEDGSEELANEIAQEIVEEFEDVEVEIHQGQQPVYPYLFSVE"
     gene            complement(13090..13455)
                     /locus_tag="VYO11_000895"
     CDS             complement(13090..13455)
                     /locus_tag="VYO11_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEV1595484.1"
                     /translation="MTVKINTKDGQIELTDEVIATVVGGAATEIFGVVGMASKNALKD
                     NFQALLGKENYSKGVVVKAAEDGSIAVDVYTVLSYGTKISEVSKNIQERVAFSLENQL
                     GITAQTVNVYIQNIKVVGE"
     gene            complement(13612..13800)
                     /locus_tag="VYO11_000896"
     CDS             complement(13612..13800)
                     /locus_tag="VYO11_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008536053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HEV1595485.1"
                     /translation="MAKVCYFTGRKTVSGNNRSHAMNQTKRAVKPNLQKVTVLIDGKP
                     KKVWASARALKSGKVERV"
     gene            complement(13916..14092)
                     /locus_tag="VYO11_000897"
     CDS             complement(13916..14092)
                     /locus_tag="VYO11_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 8"
                     /protein_id="HEV1595486.1"
                     /translation="MDSDIVVRKSIDELWDLDLTAIPLAAVRDDFYTHNFNSGVLLIN
                     DGMWRAENVTQDLI"
     gene            complement(14203..14400)
                     /locus_tag="VYO11_000898"
     CDS             complement(14203..14400)
                     /locus_tag="VYO11_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 8"
                     /protein_id="HEV1595487.1"
                     /translation="MKEEKKAIVLGADNAYMDKVETTIKSLCVHHYNLKFYVFNDDLP
                     REWFQLMEKRLETLNSEIVNV"
     gene            complement(14655..16199)
                     /locus_tag="VYO11_000899"
     CDS             complement(14655..16199)
                     /locus_tag="VYO11_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HEV1595488.1"
                     /translation="MNIQEEIKKRRTFAIISHPDAGKTTITEQLLYFGGEIREAGTVK
                     GKKTGTFAKSDWMDIEKQRGISVTSSVMQFDYDGKRVNILDTPGHEDFSEDTYRTLMA
                     VDAAVMVVDSAKGIEAQTKKLFEVVKHRGIPVFTFMNKLDRDGREPLDLLQELEEILG
                     IASYPMNWPIGMGKAFEGLYDLYNQRLELYKGDERFASLEDGDKLFGSNPFYEQVKDD
                     IELLNEAGNEFSEEAILAGELTPVFFGSALTNFGVQTFLETFLKFAPEPHGHKKTDGE
                     IVDPYDKDFSGFVFKIQANMDPRHRDRIAFVRIVSGEFERGMSVNLPRTGKGAKLSNV
                     TQFMAESRENVTNAVAGDIIGVYDTGTYQVGDTLTVGKNKFEFEPLPTFTPEIFMKVS
                     AKNVMKQKSFHKGIEQLVQEGAVQLYKNYQTGEYMLGAVGQLQFEVFKHRMEGEYNAE
                     VVMSPMGKKTVRWIKPEDLDERMSSSRNILAKDRFDQPVFLFENDFALRWFADKYPDV
                     ELEEKM"
     gene            16412..16714
                     /gene="gatC"
                     /locus_tag="VYO11_000900"
     CDS             16412..16714
                     /gene="gatC"
                     /locus_tag="VYO11_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HEV1595489.1"
                     /translation="MKITQEEVTHVANLSKLRFSEEETAAFATTLSKIVDMVELLGEV
                     DTTGVAPTTTMADRKTVLRPDVVEEGTDRDRLFKNVPEQDNYYIKVPAILDDGGDA"
     gene            16714..18180
                     /gene="gatA"
                     /locus_tag="VYO11_000901"
     CDS             16714..18180
                     /gene="gatA"
                     /locus_tag="VYO11_000901"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HEV1595490.1"
                     /translation="MTFNNKTIEELHNLLVSKEISATELTQATLENIKSREEALNSFV
                     TIAEEQALVQAKAIDEAGIDADNVLSGIPLAVKDNISTDGILTTAASKMLYNYEPIFD
                     ATAVANAKTKGMIVVGKTNMDEFAMGGSGETSHYGATKNAWDHSKVPGGSSSGSAAAV
                     ASGQVRLSLGSDTGGSIRQPAAFNGIVGLKPTYGTVSRFGLIAFGSSLDQIGPFAPTV
                     KENALLLNAIASEDAKDSTSAPVRIADFTSKIGQDIKGMKIALPKEYLGEGIDPEVKE
                     TILNAAKHFEKLGAIVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRAEDA
                     TNLDEIYVNSRSQGFGEEVKRRIMLGTFSLSSGYYDAYYKKAGQVRTLIIQDFEKVFA
                     DYDLILGPTAPSVAYDLNSLNHDPVAMYLADLLTIPVNLAGLPGISIPAGFSQGLPVG
                     LQLIGPKYSEETIYQAAAAFEATTDYHKQQPVIFGGDN"
     gene            18180..19622
                     /gene="gatB"
                     /locus_tag="VYO11_000902"
     CDS             18180..19622
                     /gene="gatB"
                     /locus_tag="VYO11_000902"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HEV1595491.1"
                     /translation="MNFETVIGLEVHVELNTNSKIFSPTSAHFGNDQNANTNVIDWSF
                     PGVLPVLNKGVVDAGIKAALALNMDIHKKMHFDRKNYFYPDNPKAYQISQFDEPIGYN
                     GWIEVELEDGTTKKIGIERAHLEEDAGKNTHGTDGYSYVDLNRQGVPLIEIVSEADMR
                     SPEEAYAYLTALKEVIQYAGISDVKMEEGSMRVDANISLRPYGQEKFGTKTELKNLNS
                     FSNVRKGLEYEVQRQAEILRSGGQIRQETRRYDEANKATILMRVKEGAADYRYFPEPD
                     LPLFEISDEWIEEMRTELPEFPKERRARYVSDLGLSDYDASQLTANKVTSDFFEKAVA
                     LGGDAKQVSNWLQGEVAQFLNAEGKTLEQIELTPENLVEMITIIEDGTISSKIAKKVF
                     VHLAKNGGGAREYVEKAGMVQISDPAILIPIIHQVFADNEAAVADFKSGKRNADKAFT
                     GFLMKATKGQANPQVALKLLAQELAKLKEN"
     gene            19751..20311
                     /gene="efp"
                     /locus_tag="VYO11_000903"
     CDS             19751..20311
                     /gene="efp"
                     /locus_tag="VYO11_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HEV1595492.1"
                     /translation="MIEASKLKAGMTFETADGKLIRVLEASHHKPGKGNTIMRMKLRD
                     VRTGSTFDTSYRPEEKFEQAIIETVPAQYLYKMDDTAYFMNTETYDQYEIPVVNVENE
                     LLYILENSDVKIQFYGTEVIGVTVPTTVELTVAETQPSIKGATVTGSGKPATMETGLV
                     VNVPDFIEAGQKLVINTAEGTYVSRA"
     gene            20333..20722
                     /locus_tag="VYO11_000904"
     CDS             20333..20722
                     /locus_tag="VYO11_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEV1595493.1"
                     /translation="MGIEEQLGEIVIAPRVLEKIIAIATAKVEGVHSFSNRSVSDTLS
                     KLSLGRGIYLKNVDEELTADIYLYLEYGVKVPKVAVAIQKAVKDAVRNMADVELAAIN
                     IHVAGIVPDKTPKPELKDLFDEDFLND"
     gene            20715..21137
                     /gene="nusB"
                     /locus_tag="VYO11_000905"
     CDS             20715..21137
                     /gene="nusB"
                     /locus_tag="VYO11_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000203663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HEV1595494.1"
                     /translation="MTSPLLESRRQLRKCAFQALMSLEFGTDVETACRFAYTHDREDT
                     DVQLPAFLIDLVSGVQAKKEELDKQITQHLKAGWTIERLTLVERNLLRLGVFEITSFD
                     TPQLVAVNEAIELAKDFSDQKSARFINGLLSQFVTEEQ"
     gene            complement(21186..21422)
                     /locus_tag="VYO11_000906"
     CDS             complement(21186..21422)
                     /locus_tag="VYO11_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV1595495.1"
                     /translation="MDVILSAIIFGISHLILSHRDPISLLYYSLIGFFFALVYRSTDN
                     LRLTILCHSFFNFLNHAKPIWIFVYNYIYYHFFR"
     gene            complement(21435..21908)
                     /locus_tag="VYO11_000907"
     CDS             complement(21435..21908)
                     /locus_tag="VYO11_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001246431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1595496.1"
                     /translation="MRNTKKLRQFGIFLLIILLSTYLPQTIGLYVTIILGLGADVYSL
                     ILTMGLVGSFLLLIWRLKKKKMLFIFEKKSWNWSFVFYLFATYVVYQILGNFWARYAH
                     LINHRNIHDEYFTVLFSNGQPTFLSTILSFVLPVIIGPVFEETLDRGYFMNTFFP"
     gene            complement(21926..22111)
                     /gene="briC"
                     /locus_tag="VYO11_000908"
     CDS             complement(21926..22111)
                     /gene="briC"
                     /locus_tag="VYO11_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm-regulating peptide BriC"
                     /protein_id="HEV1595497.1"
                     /translation="MTGTNTFTVLSTEDLEQTSGGLAVWEDGYSRWLYYREFAPYMRQ
                     GALNSYIDAWKYGFRAG"
     gene            complement(22374..23141)
                     /locus_tag="VYO11_000909"
     CDS             complement(22374..23141)
                     /locus_tag="VYO11_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HEV1595498.1"
                     /translation="MNIAKIVREAREQSRLTTLDFATGIFDEFIQLHGDRSFRDDGAV
                     VGGIGWLGDQAVTVVGIQKGKSLQDNLKRNFGQPHPEGYRKALRLMKQAEKFGRPVVT
                     FINTAGAYPGVGAEERGQGEAIARNLMEMSDLKVPIIAIIIGEGGSGGALALAVADRV
                     WMLENSIYAILSPEGFASILWKDGTRAMEAAELMKITSHELLEMDVVDKVISEVGLSS
                     KELIKSVKKELQTELARLSQKPLEELLEERYQRFRKY"
     gene            complement(23138..24004)
                     /locus_tag="VYO11_000910"
     CDS             complement(23138..24004)
                     /locus_tag="VYO11_000910"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001173351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HEV1595499.1"
                     /translation="MALFSKKDKYIRINPNRSVREKPQAKPEVPDELFSQCPGCKHTI
                     YQKDLGSERICPHCSYTFRISAQERLALTIDMGTFKELFTGIESKDPLHFPGYQKKLA
                     SMREKTGLHEAVVTGTALIKGQTVALGIMDSNFIMASMGTVVGEKITRLFEYATVEKL
                     PVVLFTASGGARMQEGIMSLMQMAKISAAVKRHSNAGLFYLTILTDPTTGGVTASFAM
                     EGDIILAEPQSLVGFAGRRVIENTVRESLPEDFQKAEFLLEHGFVDAIVKRRDLPDTI
                     ASLVRLHGGSPR"
     gene            complement(24041..25408)
                     /gene="accC"
                     /locus_tag="VYO11_000911"
     CDS             complement(24041..25408)
                     /gene="accC"
                     /locus_tag="VYO11_000911"
                     /EC_number="6.3.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000488661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HEV1595500.1"
                     /translation="MFRKILIANRGEIAVRIIRAARELGIATVAVYSTADKEALHTLL
                     ADEAVCIGPGKATESYLNINAVLSAAVLTEAEAIHPGFGFLSENSKFATMCEEVGIKF
                     IGPSGHVMDMMGDKINARAQMIKAGVPVIPGSDGEVHNSEEALIVAEKIGYPVMLKAS
                     AGGGGKGIRKVEKPDDLVSAFETASSEAKANYGNGAMYIERVIYPARHIEVQILGDEH
                     GHVIHLGERDCSLQRNNQKVLEESPSIAIGKTLRHEIGAAAVRAAEFVGYENAGTIEF
                     LLDEASSNFYFMEMNTRVQVEHPVTEFVSGVDIVKEQICIAAGQPLSVKQEDIVLRGH
                     AIECRINAENPAFNFAPSPGKITNLYLPSGGVGLRVDSAVYPGYTIPPYYDSMIAKII
                     VHGENRFDALMKMQRALYELEIEGVQTNADFQLDLISDRNVIAGDYDTSFLMETFLPK
                     YQEKE"
     gene            complement(25420..25842)
                     /gene="fabZ"
                     /locus_tag="VYO11_000912"
     CDS             complement(25420..25842)
                     /gene="fabZ"
                     /locus_tag="VYO11_000912"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HEV1595501.1"
                     /translation="MIDIQGIKEALPHRYPMLLVDRVLEVSEDTIVAIKNVTINEPFF
                     NGHFPQYPVMPGVLIMEALAQTAGVLELSKPENKGKLVFYAGMDKVKFKKQVVPGDQL
                     VMTATFVKRRGTIAVVEAKAEVDGKLAASGTLTFAIGN"
     gene            complement(25839..26324)
                     /locus_tag="VYO11_000913"
     CDS             complement(25839..26324)
                     /locus_tag="VYO11_000913"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001052236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HEV1595502.1"
                     /translation="MNLNDIKDLMTQFDQSSLREFSYKNGTDELQFSKNEARPVPEVA
                     TQVAPAPVLATPSPVAPTSAPAETVAEEVPAPAEASVATEGNLVESPLVGVVYLAAGP
                     DKPAFVTVGDSVKKGQTLVIIEAMKVMNEIPAPKDGVVTEILVSNEEMVEFGKGLVRI
                     K"
     gene            complement(26327..27562)
                     /gene="fabF"
                     /locus_tag="VYO11_000914"
     CDS             complement(26327..27562)
                     /gene="fabF"
                     /locus_tag="VYO11_000914"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000774039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HEV1595503.1"
                     /translation="MKLNRVVVTGYGVTSPIGNTPEEFWNSLATGKIGIGGITKFDHS
                     DFDVHNAAEIQDFPFDKYFVKKDTNRFDNYSLYALYAAQEAVNHANLDVEALNRDRFG
                     VIVASGIGGIKEIEDQVLRLHEKGPKRVKPMTLPKALPNMASGNVAMRFGANGVCKSI
                     NTACSSSNDAIGDAFRSIKFGFQDVMLVGGTEASITPFAIAGFQALTALSTTEDPTRA
                     SIPFDKDRNGFVMGEGSGMLVLESLEHAEKRGATILAEVVGYGNTCDAYHMTSPHPEG
                     QGAVKAIKLALEEAEISPEQVAYVNAHGTSTPANEKGESGAIVAVLGKEVPVSSTKSF
                     TGHLLGAAGAVEAIVTIEAMRHNFVPMTAGTSEVSDYIEANVVYGQGLEKEIPYAISN
                     TFGFGGHNAVLAFKRWENR"
     gene            complement(27584..28315)
                     /gene="fabG"
                     /locus_tag="VYO11_000915"
     CDS             complement(27584..28315)
                     /gene="fabG"
                     /locus_tag="VYO11_000915"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HEV1595504.1"
                     /translation="MKLEHKNIFITGSSRGIGLAIAHKFAQAGANIVLNSRGAISEEL
                     LAEFSNYGIKVVPISGDVSDFADAKRMIDQAIAELGSVDVLVNNAGITQDTLMLKMTE
                     ADFEKVLKVNLTGAFNMTQSVLKPMMKAREGAIINMSSVVGLMGNIGQANYAASKAGL
                     IGFTKSVAREVASRNIRVNVIAPGMIESDMTAILSDKIKEATLAQIPMKEFGQAEQVA
                     DLTVFLAGQDYLTGQVIAIDGGLSM"
     gene            complement(28349..29269)
                     /gene="fabD"
                     /locus_tag="VYO11_000916"
     CDS             complement(28349..29269)
                     /gene="fabD"
                     /locus_tag="VYO11_000916"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HEV1595505.1"
                     /translation="MTKTAFLFAGQGAQYLGMGRDFYDQYPIVKETIDRASQVLGYDL
                     RYLIDTEEDKLNQTRYTQPAILATSVAIYRLLQEKGYQPDMVAGLSLGEYSALVASGA
                     LDFEDAVALVAKRGAYMEEAAPADSGKMVAVLNTPVEVIEEACQKASELGVVTPANYN
                     TPAQIVIAGEVVAVDRAVELLQEAGAKRLIPLKVSGPFHTALLEPASQKLAETLAQVS
                     FSDFTCPLVGNTEAAVMQKEDIAQLLTRQVKEPVRFYESIGVMQEAGISNFIEIGPGK
                     VLSGFVKKIDQTAHLAHVEDQASLVALLEK"
     gene            complement(29262..30236)
                     /gene="fabK"
                     /locus_tag="VYO11_000917"
     CDS             complement(29262..30236)
                     /gene="fabK"
                     /locus_tag="VYO11_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000857459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-[acyl-carrier-protein] reductase FabK"
                     /protein_id="HEV1595506.1"
                     /translation="MKTRITELLKIDYPIFQGGMAWVADGDLAGAVSKAGGLGIIGGG
                     NAPKEVVKANIDKIKSLTDKPFGVNIMLLSPFVEDIVDLVIEEGVKVVTTGAGNPSKY
                     MERFHEAGIIVIPVVPSVALAKRMEKIGADAVIAEGMEAGGHIGKLTTMTLVRQVATA
                     ISIPVIAAGGIADGEGAAAGFMLGAEAVQVGTRFVVAKESNAHPNYKEKILKARDIDT
                     TISAQHFGHAVRAIKNQLTRDFELAEKDAFKQEDPDLEIFEQMGAGALAKAVVHGDVD
                     GGSVMAGQIAGLVSKEETAEEILKDLYYGAAKKIQEEASRWAGVVRND"
     gene            complement(30355..30579)
                     /locus_tag="VYO11_000918"
     CDS             complement(30355..30579)
                     /locus_tag="VYO11_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEV1595507.1"
                     /translation="MAVFEKVQEIIVEELGKDASEVTLESTFDDLDADSLDLFQVISE
                     IEDAFDIQIEAENDLKTVGDLVAYVEEQAK"
     gene            complement(30639..31613)
                     /locus_tag="VYO11_000919"
     CDS             complement(30639..31613)
                     /locus_tag="VYO11_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HEV1595508.1"
                     /translation="MAFAKISQVAHYVPEQVVTNHDLAQIMDTNDEWISSRTGIRQRH
                     ISRTESTSDLATEVAKKLMAKAGITGEELDFIILATITPDSMMPSTAARVQANIGANK
                     AFAFDLTAACSGFVFALSTAEKFIASGHFQKGLVIGSETLSKAVDWSDRSTAVLFGDG
                     AGGVLLEASEQEHFLAESLNSDGSRSECLTYGHSGLHSPFSDQESADSFLKMDGRTVF
                     DFAIRDVAKSIKQTIDESPIEVTDLDYLLLHQANDRILDKMARKIGVDRAKLPANMME
                     YGNTSAASIPILLSECVEQGLIPLDGSQTVLLSGFGGGLTWGTLILTI"
     gene            complement(31613..32047)
                     /locus_tag="VYO11_000920"
     CDS             complement(31613..32047)
                     /locus_tag="VYO11_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEV1595509.1"
                     /translation="MDYQRINEYLTSIFNNVLVIEEVNLRGSRFKDISIKEMHTIDVI
                     GKAPDVTPSQVSKELMVTLGTVTTSLNNLERKGYIERVRSEQDRRVVHLHLTKKGRLI
                     HRLHKRFHKAMVEKIIDGMSEEEIAVMGKGLTNLYQFLEDLK"
     gene            complement(32141..32926)
                     /locus_tag="VYO11_000921"
     CDS             complement(32141..32926)
                     /locus_tag="VYO11_000921"
                     /EC_number="4.2.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase"
                     /protein_id="HEV1595510.1"
                     /translation="MEHIIYQLEEDLAILTLNRPEVANGFHIPMCEEILEALTLAEEN
                     PAVHFILINANGKVFSVGGDLVEMKRAVDEDDIPSLTKIAELVNTISYKIKQIAKPVL
                     MEVDGAVAGAAANMAVAADFCLATDKAKFIQAFVGVGLAPDAGGIHLLSRSIGVTRAA
                     QLAMTGEALTAEKALEWGLVYRVSEAEKLEKTREQLLKKLRRASSNSYAAIKKLVWES
                     QFKDWQGYATLELNLQKSLAQTEDFKEGVRAHSERRRPKFTGK"
     gene            33295..34659
                     /locus_tag="VYO11_000922"
     CDS             33295..34659
                     /locus_tag="VYO11_000922"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HEV1595511.1"
                     /translation="MKVVKFGGSSLASASQLEKVLNIVKSDSERRFVVVSAPGKRNAE
                     DTKVTDALIKYYRDYVAGNDISKSQSWIIDRYAAMVSELGLKPAVLEKISKSIHALAT
                     LPIEENEFLYDTFLAAGENNNAKLIAAYFNQNGIDARYMHPREAGIVVTSEPGHARII
                     PSSYDKIEELTNTNEVLVIPGFFGVTKENQICTFSRGGSDITGSIIAAGVKADLYENF
                     TDVDGIFAAHPGIIHQPHSIPELTYREMRELAYAGFSVLHDEALLPAYRGKIPLVIKN
                     TNNPDHPGTRIVLKHSNDEFPVVGIAGDSGFVSINMSKYLMNREVGFGRKVLQILEEL
                     NIGWEHMPTGIDDLSIILRSRQLTPIKEEEILRQLVQKAKVDHAEIEHDLSIIMIVGE
                     KMKSHIGVTATATRALSENKINIQMMSQGSSEVSIMFVVNKDQEKAAIKALYNAFFGE
                     SKED"
     gene            34662..35033
                     /locus_tag="VYO11_000923"
     CDS             34662..35033
                     /locus_tag="VYO11_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HEV1595512.1"
                     /translation="MAQSLNKTVLLSTTGTSYLSIAGKVGKFLVGDQALEFYPDVNVE
                     QFIQIPWSHINQIGANVTGRKISRHFEVFTDKGKFLFASKDSGAILKIARKKLGNDKV
                     VKLPTLIQTISQKFKNLFAKK"
     gene            35247..36521
                     /gene="serS"
                     /locus_tag="VYO11_000924"
     CDS             35247..36521
                     /gene="serS"
                     /locus_tag="VYO11_000924"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000884256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HEV1595513.1"
                     /translation="MLDIKRIRTDFEAVAEKLATRGVDAAVLNEMKKIDAKRRNILVK
                     VETLKAERNTVSAEIAQAKRNKENTDDKIAAMQNLSAEVKALDAELAEIDAKLTEFTT
                     TLPNIPADSVPVGADEDDNVEVRRWGTPREFDFEPKAHWDLGEDLGILDWERGGKVTG
                     ARFLFYKGLGARLERAIYNFMLDEHGKEGYTEVITPYIVNHDSMFGTGQYPKFKEDTF
                     ELSDTNFVLIPTAEVPLTNYYRDEILDGKDLPIYFTAMSPSFRSEAGSAGRDTRGLIR
                     LHQFHKVEMVKFAKPEESYEELEKMTANAENILQKLNLPYRVVALSTGDMGFSATKTY
                     DLEVWIPAQNNYREISSCSNTEDFQARRAQIRYRDEADGKVKLLHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTIPEALRPYMGGAEVIKP"
BASE COUNT        10736 a         8445 c         6680 g        10663 t
ORIGIN      
        1 taatttctga aattaacaca ggattacctt tgaaaaaatg gactttttca agggcttttt
       61 gccgtgctct aaaatcatcg ccaaatcatc aaattgaaat aagaaatagt ttagataaaa
      121 ctattgactt ttcttatagt ttgtctttct tctatcttcc attatatcat actttttcag
      181 tctatggtag ctctctttaa aaggctccga tactgccgcc acctccgcct ccagagaagc
      241 caccgccaga acttccactt ccagaagata cggagtaggt acttgctgta tttgcgacac
      301 tagcataatg gctcatttgc gcgcttgaat gataaaacat actgtgccag ccataagcta
      361 catagagatt gatatctgga ttttcaactt gaatctgatg aaccttcatc aaatgactaa
      421 ccttgtccgc atagccaaat aaggttgcat agaccaagag acgattccaa acaacaatac
      481 tttccaattc agccttatcc agtcgtgcaa tctcacgtaa catattttca aaactggtcc
      541 agagatagta gacctcagct cccgcttcat ttagaacacc atcacgatta tctagtcgaa
      601 gcttccaata atagaaaaca gacaaaacta accctagaaa accaagtatt ggcaaaggga
      661 ggtaaagata gccatgaacg tctaaactgt acaagaacaa accaaatccg ataaataggg
      721 gcaagatagt caagacaccc atacccactt gcaaagcctt ttccaaacca gttaaaggac
      781 gatagtaatc tgggagcccc cagaaggaaa ctcgttttct cactccttct tgcatctggt
      841 tcaatacctc ttcaaaagaa gatttgagtt gaagccctct tgcttgaatc cgtttttcat
      901 cagaaacttt ggctctacga taaagactat cagatacctt gtaatccgca aacaaattgg
      961 aaagagtttc ttctttttta cctgaaaaag ctagatttag gcagtctttc tcaaagcttg
     1021 acaaaccatc ttcttttact agcctcaaac caactgcatc tccttctgaa atgatagaga
     1081 cattcccacg gtctatcaca tctagcaagg tagcttgaat aagttgatca aaggtgaatt
     1141 ttccagctcc cttgaccaag ggactcactt cctccaagga ggtcgagtag actgcttctg
     1201 ataaaaccat aggctctaat tccattgggg gttcatagag acgatgattt ttagcatatt
     1261 tgattgaagg agcggtcttt cttctataga taaaatagaa acagatgctc aataacaagg
     1321 agatggaaag gatcgaaggg aagatccaag taagtagttg tttactttga tctttttctt
     1381 taacgatcga atcctctatc ttattaaact cttctaaacg attccctttc aagccctgat
     1441 ccctagcgct agcaaaatca gttcgcggcc agtaggcatg caattcaact ccacgcttag
     1501 ccggaagatt gtctaaacga atagtataat caaggttact cttttcaacc gttctctctc
     1561 taaaaagttt ccctgtatgg aaaaagagtt tctcagcccc cttgtctccc cttacatgaa
     1621 attcaaactt ttcaatagac tctgaactat ctgtcagagg ttgccaattt aattcagcga
     1681 tatcatcata aaggaaaagt aaatttttta agttccagac gaggtcaact tcaactatgt
     1741 cgtcctcctg acctggatta tagactctca cagtataacc atccgcttct tctgttactt
     1801 cgctagtcac atctgctagt tctgcaccgt ttttcgcggc ctgaaccttt ggatgagggt
     1861 caatgtcaaa cccgctaggc atcttaccag cacgtccaag tcccacgatt tgtcccttaa
     1921 agtcctcctc aaactgataa actatctttt gtctaaattc tgccgtattg tctgcatgaa
     1981 tatacaaatc accttgataa gagtttatct taaaatcaat ggcgaaaaca gaaagtggca
     2041 gaaggcaaaa caagccaaac atcagtaaga aaaaagtttt tttcatcaat taagccccct
     2101 ttttatcttt cttatcatta tagcattttt tcgtaagtaa aggcttactt atgttgaaaa
     2161 attacgcatt tttcgataaa ataggagaca gttatttttt aatagattag aaataggaga
     2221 aatcatgaga aaaatatact tatctatttt cacaagtctc ttgctgatgc taggacttgt
     2281 caatgttgct caagccgatg aatatttacg catcgggatg gaagcagcat atgctccctt
     2341 taactggacc caagatgatg atagcaatgg agctatcaaa atcgatggaa ccaaccagta
     2401 cgccaatgga tacgatgtcc aaattgccaa gaaaatcgct aaggacttag gtaaagaacc
     2461 tttggttgtt aaaaccaagt gggaaggtct agtccctgcc cttacttctg gtaagattga
     2521 catgattatc gcaggtatga gtcctactgc cgaacgcaaa caagaaattg ccttttcaag
     2581 cagttactat actagcgaac cagttttgct tatcaaaaaa gattctgcct acgcaagtgc
     2641 taaatctttg gatgacttta acggtgcaaa aatcacttct caacaagggg tctacctcta
     2701 cgacttgatt gcacaaatcc caggtgctaa aaaagaaaca gccatgggag acttcgctca
     2761 aatgcgccaa gctcttgagg ctggtgtcat tgatgcttat gtctctgaac gtccagaagc
     2821 actgactgct gaagctgcga actctaagtt caagatgatt caagtagaac ctggtttcaa
     2881 aactggggaa gaagatacag ctatcgctat cgggcttcgt aaaaatgaca atcgtattag
     2941 ccaaatcaat gccagcattg aaaccatttc aaaagatgac caagttgcct tgatggatcg
     3001 tatgatcaag gaacaacctg ccgaagctac aacaactgaa gagactagca gtagtttctt
     3061 tagccaagtc gctaaaattc tttctgaaaa ctggcaacaa ctcttgcgtg gtgctggtat
     3121 cactctttta atctctatcg tcggaaccat cataggtctc attattggac ttgccattgg
     3181 tgtcttccgt actgctcctc tctctgaaaa caaagccatt tatggccttc aaaaactagt
     3241 cggctgggtt ctcaatgtct acattgaaat tttccgtggt acgccaatga ttgttcaatc
     3301 gatggttatc tactatggaa ctgcccaagc tttcgggatc aaccttgacc gtacactggc
     3361 tgctatcttc atcgtttcaa tcaataccgg tgcctacatg actgaaatcg tccgtggtgg
     3421 tatcctagca gttgacaagg gacaatttga agctgcgact gctcttggta tgacccataa
     3481 ccagaccatg cgtaagattg tcctacctca ggtagtccgt aacatcctac ctgcaactgg
     3541 taatgaattt gtcatcaata tcaaagatac atctgtattg aacgttatct ctgttgtcga
     3601 actttatttc tcaggaaata ccgtggcaac acaaacctat caatacttcc agacatttac
     3661 aatcatcgcc gtgatttact ttgtcctcac cttcaccgta acacgtatcc tacgctttat
     3721 cgagcgcaga atggacatgg atacctacac tacaggtgct aaccaaatgc aaacggagga
     3781 tttgaaataa tgacacaagc aatccttgaa attaaacacc tcaaaaaatc ctatggacaa
     3841 aacgaagtgc taaaagacat ttcactcact gtccacaagg gagaggtcat ctctatcatc
     3901 ggaagctctg gaagcggaaa atcgaccttc ctacgctcca ttaacctact tgaaacacca
     3961 actgatggac aaatccttta tcatggacaa aacgtcctcg aaaaaggcta tgacctcacg
     4021 caataccgtg aaaagttggg gatggttttc caatccttta acctctttga aaatctcaat
     4081 gttcttgaaa acacaatcgt cgctcagaca actgtcctaa aacgcgaacg cacagaagct
     4141 gaaaagattg ccaaagaaaa cctggaaaag gtcggcatgg gagaacgcta ctggcaagcc
     4201 aaaccaaaac aactctcagg tggtcaaaaa caacgtgtgg ccatcgctcg tgccctctcc
     4261 atgaatccgg acgctattct ctttgatgaa ccaacatcag ctctcgatcc agaaatggtt
     4321 ggagaagtcc tcaaaatcat gcaggacctg gctcaggaag gcttgaccat gattgtcgta
     4381 acccatgaaa tggaatttgc ccgtgatgtc tctcaccgtg ttatctttat ggataagggc
     4441 gtgatcgctg aagaaggtaa accagaagac ctcttcacca atcctaaaga agaccgaaca
     4501 aaagagttcc ttcaacgcta tctcaaataa aaagaaaagg ctgcatcaac cgtgcagtct
     4561 ttttgctgtc ctcaaaatga aaaggcagat tctctatctc tactacttga aggtcaagaa
     4621 tccgccgtta tccaaagatt aatcttcaaa tttttcataa tttttttcat agaaatcaat
     4681 taggcctagg gctgtttcaa atgaaatatt ttttactttt gcacgaccct gcgccagagc
     4741 aatgatagac atttcacgcg cattcgtttc tttagagata cggtagcctg tgattttctt
     4801 atcacgaacc cagccaacaa ctgattctac tttttcaaag tttgacttag ccatgttttt
     4861 ctcctatttt cttctttata atatttaatt gtatacgttt ttactacttt tgtcaataaa
     4921 aaaaacatat attcaacgaa aataattagt tcagaatttt cttacttcct ttttaaatcc
     4981 gataatatat aggttttgct agcctctaca ccataaatat ttgctaataa aaatactgta
     5041 ttattaccct cttaaggtgc gaaattattc aagttcttaa aaaatgcttc tctatttccg
     5101 taagatagct tatttcttcg atttaagaac tgaagatgat agttctaacc tttagaaatc
     5161 caagccttca ctagctcaaa aactcctatc tttcttcctc aataaatcat ctgagagata
     5221 ggtattcctt atgtccttca aattcatcac tcctttggat attgaggtgc tagcctagaa
     5281 gcagacaccc gattatctaa accatcctta ataaagatga caagacagat aagctcagtt
     5341 aattacttat atatcttttt aatatggtat atttgtcaac aaaaagaaat caaatcatac
     5401 cttatactca atgaaaatca aagagcaaac taggaagcta gccgcaagtt gctcaaaaca
     5461 ctgttttgag gttgcagata gagctaacgt ggtttgaaga gattttcgaa gagtattaaa
     5521 gacagtgtga ctatgcttgt caatagatag gaaatcaaaa tgaaggatgg aaatctgagc
     5581 caaacatcat aagtgctata atgaacagaa gtaagaattg cacgataagt tttctaaaac
     5641 cataggaatc gtcccctttc ttcatcttca ttatagcaca tatacatcag ttgtacaaat
     5701 aatatgatat ttttttatta gtcctcagac aagcatatta taaagcgttt cattaccatt
     5761 taagttaata taagctggat caaaaccttc cattctacga atcaaacctg cataatcatg
     5821 cttatctgct aaagcgatcc caattaatac tgggcctgtt cccttgctag ctcgtttgat
     5881 atactcaaaa cgtgtgatat catcatttgg ccccaggata tcatttacaa actcacgcaa
     5941 agctcctgga cgttgtggga aattgaccac aaagtaatgt ttgataccat cataaatcaa
     6001 ggcacgctct tccatttctg gcatacggtt gatatcatta tttcctccag aaatgataca
     6061 acaaatggtt ttccccttaa tatattcagc taaaacctct aaagaggcga tactagccgc
     6121 tccagcaggt tctgcgacta tcccttgctt agagtaaagg tcaatcaagg tttcagaaat
     6181 caatccctca tcgacaccta ccaaagtttg aatatgttga cgagttgctt cataggtcaa
     6241 ctgacctacc ttttgcacag caatcccatc cgcaaattta tcaatttcct tgagttttac
     6301 tggacctcca gcctcaaagg cagctttcat ggaacgcgct ccattcgcct ctactccgat
     6361 aacctcaatc tctggacttg tttccttgat ataggtagaa accccggcaa tgagaccgcc
     6421 accaccaaca ggaaccaaga cagcatcaaa atcaatcgat tcttttcgag cttcttctaa
     6481 aatctcataa gcaactgttc cttgacctgc ttgaacatga gcatcatcaa aaggatcaat
     6541 aaaggtacga ttttcagaga ctgtaaattc ttgagctgct ttggctgagg catcaaaggt
     6601 atctccaact agtttaatag ttacaaaatc cccaccaaaa aagcgaacct gaccaatctt
     6661 ttgttgtggc gtagtaatag gcataaagat agtagcagga attttcattt cattacaagt
     6721 ataggctact ccctgcgcat gatttcccgc agaagcgcag actaccccac gttcacgttc
     6781 ttccttgctg agctgggaaa tggcataata ggcaccacga attttaaagg agcgaacacg
     6841 ctgggcattt tcttttttca aataaatctt agcaccatac ttctccgata aataatgatc
     6901 gtaatccagt ggagtattca caaccacacc gttcaagacc ttgtgagcct tgattatatc
     6961 ttttgaactt aacatataaa acctcttttt ctataaaaaa cagtcactaa tgactgtttt
     7021 ttagttattc atctccgaaa acttcagtaa cactttcatg gtatttatga gccatacgaa
     7081 tcgaaaactc tttaggaagt tcataacgat ttgtggaaat ccaatcatat aaccattcta
     7141 ccaaactttc ttcactatca ttacgatgga agataaaata gtttaaaatt tctttatatt
     7201 ctacatcatt caaatccaac gtgtctacaa attgactacg aggaacaaaa ttagaatcta
     7261 attttcttag ttgatctgtc aattctccca attgtaaatc caactgaaaa aatagttttt
     7321 gcagttgcct atcagtttca tcacatcctg tcttgataga aaacaaattg gtaatattca
     7381 tatgatttca acccctaaat aagtacatct aatatcccac gaatagctga agctaaagtt
     7441 ttcgcagtcc agtcatttaa acccgattct ttcaatccag atgcaataat ttgctctatt
     7501 tgatataaac cgccatctat cgtctcattt attctgcgaa gaggaccttc aatataggat
     7561 aaagcttctc cgaatctaac agctgattta ggtcctaatg atttaccaac tatatttgtt
     7621 aatgtttttt atttctcaaa atccatttcg ctatataacg agcagattta gtcgcgccag
     7681 ctctctcaaa cggagaatga atttcaagac cttcttctct agctatttgt gccaatttga
     7741 agaattgttc aaaggtcata tgcaacctac catcttcaaa attagcatca tcataaatgt
     7801 taattacagc attttcatca tacgaccaat ctgctttatt ttggtctgct agcactatta
     7861 ccgacggtgt aattacatta tacaactaga accaataata acgatgcaat ttttctcata
     7921 atctttttca taaaatcatc tccagcgcta tatatttcta attagttata gattttgaat
     7981 gcatcatcgt cgtttttacc aacgaatggc attgctttac gcaattctgc accaactttt
     8041 tcaatttcaa ggttagctgc ttgttcacgg taagcagtca attttggacg tccagcttta
     8101 tagtcattta caaagtcatt tgcaaattta ccattttgga tgtctgccaa gacagccttc
     8161 atattttctt taacttgttc agtgattaca cgtggacctg atacatagtc accgtattca
     8221 gcagtgtttg aaatagattg acgcattttc ttgaatccac cttcgtagat caagtcaacg
     8281 atcaatttca tttcgtgaag aacttcaaag taagccaatt ctggagcgta acctgcttct
     8341 gtcaagactt cgaaacctgc ttcgataagg gcagtcaaac caccacaaag tacagcttgt
     8401 tcaccaaaca aatcttcttc agtttcttct ttgtaagttg tttcaagaag acctacacga
     8461 gccgctccaa cacctttaca ccagtccata gcaatgtttt tagcatttcc tgttgcatct
     8521 tggtatactg cataaagagc tggaacacca aatccttctt cgtaagtacg acgtaccaag
     8581 tgtcctggtc ctttaggagc acacatgaag acatctacat ccgcgggaac tttgataaat
     8641 tcaaagtgga tgttgaaacc atgggcaaat ccaactgcgt ttccagcttc caagtttgga
     8701 gcgatttctg cttcgtacaa ttcttgttga atttcgtctg gcaccaagat catgataaca
     8761 tcagccaact tagtagcttc tgctactgtg taagtatcaa atccatcttc ttttgcttta
     8821 tcaaaagatt tacctggacg tacacctata ataacgtcac gacctgaatc acgcaagttt
     8881 tgagcatgcg catgcccttg tgaaccataa ccgataacgg cgattttttt accgtcaagt
     8941 gctgctactt taacatcttt ttcatattcc atttgaactg tcatagcttt tctctctttt
     9001 ctattattta ttgcctttta ggctggttta ataaatttaa gttggatttt taatcgcggg
     9061 taaatccagt tgcacccgtt cgagcaatat tgcgaatacc gtatgggcga atgactcgca
     9121 atagggcttc gctcttttct gcatttcccg tcatctgaat ggtaatcgag cttggcgcta
     9181 cgtctaccac tgttgcacgg aaaggttgaa taatcgctaa aatctcagct ctcttctcag
     9241 ctggcgctga catcttaacc aaaatcacct cgcgctccaa atgaggcttg tctgtaatat
     9301 ctcgaatgcg aatcacatca atctgacgat tgagctgttt gatgatttgc tccacttcat
     9361 catgagaagc aacatcaata ataatagtga tacgcgatac attcggatct tctgttgctc
     9421 caacagagat gctttcaata ttaacctgac gacgagatag gacacctgta aagcgattga
     9481 ggactcctga acgattttgt aattttgctg ttaacattct acgcatggaa ctgcaccccc
     9541 aacatctcat gattactctt accagccggt accattggta acacctgttc cttacgagaa
     9601 atatctacct caattagcat aggaacatcc tcagtgatga tttcaaggtc ttgagccaag
     9661 gtctcaggat tgtcaaactt atagttttta ataccataag cctgcgccat caattggaaa
     9721 tcaggaaggg tatcaaagac cgactctgat gttctgcctt catagaagga ttcctgccac
     9781 tggcgaacca ttccaagtga atgattgttc agcataacca ccttgattgg caccttgtaa
     9841 atattcaaaa tagccaactc ctggttggtc atttggaaac caccatcccc aacaaacaag
     9901 actacttcct tatctgggtt agcaatttta gcaccgattg ctgctggaat tccaaagccc
     9961 attgttccca aaccacctga agtcactaac tgacgctcat tttggtaggg ataatactga
    10021 gctgtccaca tttggtgttg accaacgtct gttaccacaa tggcatctcc attcgtcaat
    10081 tcaccaattc gttcaataac tgcttgcggt tgaaccacac gctctttctt gtcataagaa
    10141 cgaacacgat tcttgtcttt agtgactttc tcaatccact tttcagtatt gttgtgaact
    10201 gttggttctg ctagcaacat ttgcaaggcc ttcttagcat ctccaactac aggaatgtct
    10261 gcactgataa tcttgccaat ctcagctggg tcaatatcaa tgtgggcaac cttagcattc
    10321 ttagcgaaag tcttaggatt ccccgtcaaa cggtcatcga aacgagaacc aatactaatc
    10381 ataaagtccg cttccgtcat ggcaatattt gctgcgaatg acccgtgcat gcctcccatt
    10441 ccaagaaaga gtgggtgact cgttgcaatc gttccttgtc ccaaaagact ggttaccact
    10501 ggaatttgat agcgttctgc aaattcattt agttccgtag cagcctcagc ataactaatt
    10561 ccaccaccag ctaacaagac tggcttttta gccttggaca attgcttcaa gattttcttg
    10621 atttgcatat cattcggctc aagagtcggc tgataacttg gtaaattcac ttctggtaaa
    10681 taaatgaagt ctgtttctaa agcagatatg tcttttggta ggtcaattac aactggccct
    10741 ggacggcctg tagttgcgat atggacagct tccgtgatga tacgcggaat atcagctgtc
    10801 tcacgaactt ggtaattgta cttagtgatt ggcatggtaa ttcccacgat gtctgcctcc
    10861 tgaaaggcat ccttcccaat ccctgctcgc gccacctgac ctgtaaagac caaaagggga
    10921 acgctatcgc tcatggcatc cgcaatccct gtaatggcat ttgttgctcc tggtccacta
    10981 gtgacaacgg caacacccaa ctttccagtt gatttggcat aaccttcagc ttcatgcaaa
    11041 caaccttgct catggcgccc tagaatgtgg cgaatgcctt taaaattata tatcgcatca
    11101 taaaaaggca aaaccgcacc accaggataa ccaaagatgg tatcaactcc taaatcacga
    11161 agtgtttcca aaactaggtc cgaccccgtc ttaggagatt ctaaactgat tttctccatt
    11221 gttccccttt ctttcctctt aaaaataact tgttactatc ataccatttt ttcaaaattt
    11281 ttcaagataa aagaagaaat tttctgaatt ttctatttta acgtttattt atgaatatta
    11341 tttttatttt tattaaaaag ataccgattt catttactaa aaaagaaaaa agaactgatt
    11401 tctcagtcct tcattaatct tattccacac taaataggta tgggtaaaca ggttgttgac
    11461 cttggtgaat ctcgacttca acgtcttcga attcttctac gatttcttga gcgatttcat
    11521 tggcaagttc ttcgcttccg tcttcaccga catagaaggt tacgatttca ctgtcttcat
    11581 ccaacatatg tttcaaggtt tcagtcaatg tttggtgcat atcagggttt gacacaagaa
    11641 tttttccatc caccatacct agattatcgt tttcatggat ttctaagcca tcgatcgttg
    11701 tatcacgcac ggctgttgtg acgcttccgc taacgacatc gctaagagca gctgtcatac
    11761 gctcttggtt ttcttcaatg gacttgcttg gatcaaaggc aagaagactt gtcatacctt
    11821 gaggaagagt gcgagcctct accactactg ctggttgctc caaaacttct gccgcagatt
    11881 gagctgccat gaagatgttc ttgttgtttg gcaagaagat gatgttacgg gcattgacct
    11941 gttcaacagc cttgataaag tcttctgttg aagggttcat ggtttgaccg ccttcgataa
    12001 catagtccac gccttgagaa cagaagatat ctgttagacc tttaccagcc accacagcaa
    12061 ttaaagcata ctctttttct tcagccgact tgataacttg agtagcttct ttctcaacct
    12121 gtgcttcgtg ttggttacgc atattgtcaa cttttacctt gaccaagcta ccatatttga
    12181 gaccttcttg cataacaagt cctggatctt ctgtatgaac atggactttg acaatttcat
    12241 catcgttaac aacgaggaga gaatccccaa gctcatccaa gtagttacgg aattcatcgt
    12301 aatcaaaatc tttagcatag gttggacctt gcttaagagc taccatgatt tcagtacagt
    12361 aaccaaacgt gatgtcctca gtcgctacgt gaccagctac agacttatga tgctctacat
    12421 tgatcatctc actcatgttg gcaggagtcg ctacaaagtc ctcagatgca atatattcgc
    12481 cagtaagggc tgaaaggaaa ccttcgtaga tgaagaccaa tccttgacca cctgagtcca
    12541 caacgccaac ttctttcaat actggaagca tgtctggtgt tttagctaga gctgttttag
    12601 caccttccaa ggctgcgcgc atgacttcaa cagtgtcatc tgtttgctca gcttttttct
    12661 tagcaccgat agcagctcca cgagaaactg tcaaaatcgt tccttcaaca ggtttcatca
    12721 ctgccttata ggcaacttcc acacctgatt ggaaggccag agccaagtct tgacctgtta
    12781 actcgtcttt atccttgata gcttgggaaa atccacggaa aagctgagac gtaatcactc
    12841 ctgagttccc acgcgcaccc atcaaaagcc ctttggcaag aatgctcgct acttctccaa
    12901 ctgtagaagc tggcttgtct gcaacttctt tagcaccatt ttcaatggtc attcccatat
    12961 ttgtcccagt atctccatct ggaactggaa agacgtttaa tgaattgaca tattcagctt
    13021 gcttattcaa gcgagttgat gcagcctgca ccatttcttg aaataagcta gtagtaattt
    13081 ttgacacggt tattctccta caactttgat attttgaatg tagacattta cagtctgagc
    13141 agtaattcca agctggtttt ccaagctaaa ggcaacacgc tcttgaatgt tttttgacac
    13201 ttcactaatc tttgttccgt agcttaacac ggtatataca tcaactgcaa tactgccatc
    13261 ttcggctgcc tttacgacga cacctttaga ataattttcc ttacctagca gggcttggaa
    13321 attatctttg agggcatttt tactagccat accgaccaca ccaaaaatct cagttgctgc
    13381 tccacctacg acggttgcaa tcacttcatc tgttagttcg atttgaccat cttttgtatt
    13441 aatttttaca gtcatccttt ttacctcaac tagttgatac tctattttat catatttcag
    13501 cccaagtgta aaagcagaat gatgtatcag cggatattta ctctattttt caaacgatgt
    13561 tatacccaca ataaaagaaa aaagacccta aggtctcctt tgcttttatt attaaacgcg
    13621 ttcaacttta cctgatttca aagcacgagc tgaagcccaa acttttttag gtttaccatc
    13681 gataagaaca gtaacttttt gaaggtttgg ttttacggca cgttttgttt ggttcatcgc
    13741 gtgtgaacgg ttgtttcctg atacagtctt acgacctgta aagtaacata ctttagccat
    13801 tgtgttttcc tcctattaga tctaatatag cggatgtgct agcaccacat accgtactat
    13861 gttatcacac tttcttgttt tttgcaaggg aattggaaga ttttttattt gtgtcttaaa
    13921 tcaggtcttg cgtgacattt tctgctctcc acatgccatc gttgattaac agaacaccag
    13981 aattaaaatt atgtgtataa aaatcatctc taactgcagc taagggtata gccgtcaagt
    14041 ccaaatccca cagctcatct atcgattttc ttacaacaat atctgaatcc aaatacagta
    14101 cacgagactc gcttacatac tttggaataa aatacctaaa aaagccgcat atgaaagtcc
    14161 ctcaaagggg agacgataac ctttcagaat actactgtca atctaaacat tcacaatctc
    14221 actattcaaa gtctctagtc ttttttccat taattggaac cattctcgcg gaaggtcatc
    14281 attaaaaaca taaaacttaa gattataatg atgaacacaa agagatttta ttgttgtttc
    14341 aactttatcc atataagcat tatctgcacc taagacaatc gcttttttct cttctttcac
    14401 tttttatctc atttcttttt attcccatca tatgtttcta cgtaaccatt attttcgcct
    14461 attcgttcgt aaaaccatac cagtggagat tttagatgaa gtcccattac ggtttacaat
    14521 ttttacatta cgacacagag ttttacaaat cgatttcatt tgccaaacgt agttagtgag
    14581 gcagttagct agttcgccaa atagcgacta gcgtccaaca atttggaact ttagttccaa
    14641 ttgttggtac tgagtcacat cttctcctct aactctacgt ctggatactt gtccgcaaac
    14701 cagcggaggg caaagtcatt ttcaaagaga aagactggtt ggtcaaaacg gtctttggct
    14761 aagatattgc gacttgacga catccgttca tccaagtcct caggcttgat ccaacgaacg
    14821 gtctttttac ccattgggct catgaccact tccgcattgt attcgccttc catacggtgt
    14881 ttaaagactt caaactggag ttgaccaaca gcgcctagca tgtactcacc tgtttggtaa
    14941 ttcttataaa gctgaacggc tccttcttgc accaattgct caatcccctt gtggaaggat
    15001 ttttgcttca taacattctt agcagaaact ttcatgaaaa tttcaggagt aaaggttggc
    15061 agtggttcaa attcaaactt gttttttcca accgtcaagg tatccccaac ctgataagta
    15121 ccggtatcgt aaaccccgat aatatcacct gccacggcat tggtcacatt ctcacgactc
    15181 tccgccataa actgggtaac attagatagt ttagccccct taccagtacg agggagattg
    15241 acactcatgc cgcgctcaaa ttcgcctgat acgatacgga caaaggcaat acggtcacgg
    15301 tgacgaggat ccatgttggc ttggatttta aagacaaagc ctgagaaatc cttgtcataa
    15361 ggatccacaa tttcaccgtc tgttttcttg tgaccatgtg gttctggagc aaacttgagg
    15421 aaggtttcaa ggaaggtctg cacaccaaag tttgtcaggg ctgaaccgaa aaagacaggc
    15481 gtcaattctc cagccaaaat agcttcctct gaaaactcat tcccggcttc atttaaaagc
    15541 tcaatgtcat ccttgacttg ctcgtagaaa ggattgctac caaagagttt gtccccgtct
    15601 tctagactgg caaaacgctc atcccctttg taaagctcta aacgttggtt atagaggtca
    15661 tacaagccct caaaggcttt ccccatcccg ataggccagt tcatagggta gctagcaatg
    15721 cccaagattt cttccaattc ttgcaacaga tccaaaggct cacgaccgtc acggtccagc
    15781 ttgttcataa aggtaaagac tggaatgcca cgatgtttca caacctcaaa caatttcttg
    15841 gtttgagcct cgatcccctt ggcagagtcc acgaccatga ccgcagcatc caccgccatc
    15901 aaggtacgat aggtatcttc tgagaagtcc tcgtgccctg gcgtgtctaa gatattcacg
    15961 cgcttgccgt cgtagtcaaa ttgcataaca gatgaagtaa cagaaatccc acgttgcttc
    16021 tcgatatcca tccagtcaga tttagcaaaa gtccctgttt tcttcccttt taccgtacca
    16081 gcctcacgaa tctcaccccc aaagtagagt aactgctcag tgatggttgt tttccccgcg
    16141 tccgggtggg aaataatggc aaaggtacga cgtttcttaa tttcttcttg aatattcata
    16201 agttctcttt ctttgattct ctatttttct tgtttcaata gctgagaatg atttttacat
    16261 tggattttac cattcctttc aacactccat tatatcggat tttagcattt ttttcaattt
    16321 ctatttcttt tcacttcccc ctcccttatt tataggaaaa tatggtaaaa tagaacagac
    16381 taaaaatcat catttcacga aaggatgcaa gatgaaaatt acgcaagaag aggtaacaca
    16441 cgttgccaat ctttcaaaat taagattctc tgaagaagaa actgctgcct ttgcgaccac
    16501 cttgtctaag attgttgaca tggttgaatt gctgggcgaa gttgacacaa ctggtgtcgc
    16561 acctactacg actatggctg accgcaagac tgtactccgc cctgatgtgg tcgaagaagg
    16621 aacagaccgt gatcgcttgt ttaaaaacgt acctgaacaa gacaactact atatcaaggt
    16681 gccagctatc ctagacgatg gaggagatgc ctaatgactt ttaacaataa aactattgaa
    16741 gagttgcaca atctccttgt ctctaaggaa atttctgcaa cagaattgac ccaagcaaca
    16801 cttgaaaata tcaagtctcg tgaggaagcc ctcaattcat ttgtcaccat cgctgaggag
    16861 caagctcttg ttcaagctaa agccattgat gaagctggaa ttgatgctga caatgtcctt
    16921 tcaggaattc cacttgctgt taaggataac atctctacag acggtattct cacaactgct
    16981 gcctcaaaaa tgctctacaa ctatgagcca atctttgatg cgacagctgt tgccaatgca
    17041 aaaaccaagg gcatgattgt cgttggaaag accaacatgg acgaatttgc tatgggtggt
    17101 tcaggtgaaa cttcacacta cggagcaact aaaaacgctt gggaccacag caaggttcct
    17161 ggtgggtcat caagtggttc tgccgcagct gtagcctcag gacaagttcg cttgtcactt
    17221 ggttctgata ctggtggttc catccgccaa cctgctgcct tcaacggaat cgttggtctc
    17281 aaaccaacct acggaacagt ttcacgtttc ggtctcattg cctttggtag ctcattagac
    17341 cagattggac cttttgctcc tactgttaag gaaaatgccc tcttactcaa cgctattgcc
    17401 agcgaagatg ctaaagactc tacttctgct cctgtccgca tcgccgactt tacttcaaaa
    17461 atcggccaag acatcaaggg catgaaaatt gctttgccta aggaatacct aggcgaagga
    17521 attgatccag aggttaagga aacaatctta aacgcggcca aacactttga aaaattgggt
    17581 gctatcgtcg aagaagtcag ccttcctcac tctaaatacg gtgttgccgt ttattacatc
    17641 atcgcttcat cagaagcttc atcaaacttg caacgttttg acggtatccg ttacggctac
    17701 cgcgcagaag atgcgactaa tcttgatgaa atctatgtaa acagccgtag ccaaggtttt
    17761 ggtgaagaag tgaagcgccg tatcatgctg ggtactttca gtctttcatc aggttactac
    17821 gatgcctact acaagaaggc tggacaggtc cgtacactta tcattcaaga tttcgaaaaa
    17881 gtcttcgcgg attatgattt gattttgggt ccaactgctc caagtgttgc ctatgacttg
    17941 aattctctca accatgaccc agttgccatg tacttagccg acctattgac catacctgta
    18001 aacttggcag gactgcctgg aatttcgatt cctgctggat tctctcaagg tctacctgtc
    18061 ggactccaat tgattggtcc caagtactct gaggaaacca tttaccaagc tgctgctgct
    18121 tttgaagcaa caacagacta ccacaaacaa caacccgtga tttttggagg tgacaactaa
    18181 tgaactttga aacagtcatc ggacttgaag tccacgtaga gctcaacacc aattcaaaaa
    18241 tcttctcacc tacttctgcc cacttcggaa atgatcaaaa tgccaacact aacgtgattg
    18301 actggtcttt cccaggagtt ctgccagttc tcaataaagg ggttgttgat gccggtatca
    18361 aggctgctct tgccctcaac atggacatcc acaaaaaaat gcactttgac cgcaagaact
    18421 acttctaccc tgataatccc aaagcctacc aaatttctca gtttgatgag ccaatcggtt
    18481 ataacggctg gattgaagtc gagctagaag acggtacgac caagaaaatt ggtatcgaac
    18541 gcgcccactt agaggaagac gctggtaaaa acacccacgg tacagacggc tactcttacg
    18601 ttgaccttaa ccgccaaggg gtacctttga ttgagattgt atctgaagcc gatatgcgtt
    18661 cgccagagga ggcctatgct tatctgacag cactcaagga agttatccag tatgctggca
    18721 tttctgacgt taagatggag gaaggttcga tgcgtgtgga tgccaacatc tcccttcgtc
    18781 cttatggtca agagaaattc ggtaccaaga ctgaattgaa gaacctcaac tccttctcaa
    18841 acgttcgcaa ggggcttgaa tacgaagtcc aacgccaggc tgaaattctt cgctcaggtg
    18901 gtcaaatccg ccaagaaaca cgccgttacg atgaagcgaa taaagcaacc atcctcatgc
    18961 gtgtcaagga aggggctgct gactaccgct acttcccaga accagaccta cccctctttg
    19021 aaatttctga cgagtggatt gaggaaatgc ggactgagtt gccagagttt ccaaaagaac
    19081 gtcgtgcgcg ttatgtatct gaccttggtt tatcagacta cgatgctagt cagttgactg
    19141 ctaataaagt cacttctgac ttctttgaaa aagctgttgc cctaggtggt gatgccaaac
    19201 aagtctctaa ctggctccaa ggggaagtcg ctcagttctt gaatgctgaa ggtaaaacac
    19261 tggaacaaat cgaattgaca ccagaaaact tggttgaaat gattaccatc atcgaagacg
    19321 gtactatttc atctaagatt gccaagaaag tctttgtcca tctagctaaa aatggcggtg
    19381 gcgcgcgtga atacgtggaa aaagcaggta tggttcaaat ttcagatcca gctatcttga
    19441 tcccaatcat ccaccaagtc tttgccgata acgaagctgc tgttgccgac ttcaagtcag
    19501 gcaaacgtaa cgccgacaag gcctttacag gattccttat gaaggcaacc aaaggccaag
    19561 ccaacccaca agttgccctt aaactacttg cacaggaatt ggcgaagttg aaagaaaact
    19621 agacagaaca aaaccagccc taaggttggt tttttcttct ctaccaactc ccaataacta
    19681 ttttggcttt atttccagag tattttatgg taaaatgaag agtaataata tttattaaag
    19741 aggtaaaaac atgattgaag caagtaaatt aaaagctggt atgacctttg aaacagctga
    19801 cggcaaattg attcgcgttt tggaagctag tcaccacaaa ccaggtaaag gaaacacgat
    19861 catgcgtatg aaattgcgtg atgtccgtac tggttctaca tttgacacaa gctaccgtcc
    19921 agaggaaaaa tttgaacaag ctattatcga gactgtccca gctcaatact tgtacaaaat
    19981 ggatgacaca gcatacttca tgaatacaga aacttacgac caatacgaaa tccctgtagt
    20041 caatgttgaa aacgaattgc tttacatcct tgaaaactct gatgtgaaaa tccaattcta
    20101 cggaactgaa gtgatcggtg tcaccgttcc tactactgtt gagttgacag ttgctgaaac
    20161 tcaaccatct atcaaaggtg ctactgttac aggttctggt aaaccagcaa cgatggaaac
    20221 tggacttgtc gtaaacgttc cagacttcat cgaagcagga caaaaactcg ttatcaacac
    20281 tgcagaagga acttacgttt ctcgtgccta atctctagaa agaggtcatt ctatgggaat
    20341 tgaagaacaa cttggcgaaa tcgttatcgc cccacgtgta cttgaaaaaa tcattgctat
    20401 cgctactgca aaggtagagg gtgttcactc tttttcaaac agatcagtgt ctgataccct
    20461 ttcaaaactt tcactcggcc gtggcattta tcttaaaaac gtggacgaag aactcacagc
    20521 agatatctat ctctaccttg agtacggagt aaaagttcct aaggtagcgg ttgctatcca
    20581 gaaagctgtc aaagatgccg tccgtaatat ggctgatgta gaactcgctg ctatcaatat
    20641 tcacgttgca ggtatcgtcc cagataaaac accaaaacca gaattgaaag atctatttga
    20701 cgaggacttc ctcaatgact agtccactat tagaatctag acgccaactc cgtaaatgcg
    20761 cttttcaagc tctcatgagc cttgagttcg gtacggatgt cgaaactgct tgtcgtttcg
    20821 cctatactca tgatcgtgaa gatacggatg tacaacttcc agcctttttg atagacctcg
    20881 tttctggtgt tcaagctaaa aaggaagaac tagataagca aatcactcag catttaaaag
    20941 caggttggac cattgaacgc ttaacgctcg tggagagaaa cctccttcgc ttgggagtct
    21001 ttgaaatcac ttcatttgac actcctcagc tggttgctgt taatgaagct atcgagcttg
    21061 caaaggactt ctccgatcaa aaatctgccc gttttatcaa tggactgctc agccagtttg
    21121 taacagaaga acaataaaaa gaaaaagtgt ttgatagata tcaaacactt tttctttgcc
    21181 tcccactatc taaaaaaatg ataatagata taattgtaaa caaaaatcca gataggtttt
    21241 gcatgattga gaaagttaaa aaaactatgg cagagaatcg ttaatctcag attgtcggta
    21301 gaacgataaa caagggcaaa aaagaaacca atcagactat aatataataa actaattgga
    21361 tctctgtgag atagtatcaa atggctaatc ccaaagatga tagcagatag gataacatcc
    21421 aaatagtact tggactaggg aaagaaggta ttcataaaat accctctatc aagagtctcc
    21481 tcaaaaacag gaccgatgat tacaggcagg acaaaagata agatagtcga taaaaaggtt
    21541 ggttgtccat ttgaaaaaag cacggtaaaa tactcatcat gaatattcct atgattaatc
    21601 aaatgagcat agcgtgccca aaaattaccg agaatctgat aaaccacata agttgcaaat
    21661 aagtagaaga caaatgacca gttccagctc tttttctcaa agataaagag catctttttc
    21721 ttttttaacc tccaaattaa tagaaggaaa cttcccacta atcccattgt taaaataaga
    21781 gaatagacat cagctcctaa ccctaaaatg atcgtcacat acaatccaat tgtttgtggt
    21841 aaataggtag atagtaaaat aataagcaaa aatattccaa attgtcttag tttttttgtg
    21901 tttctcatcg tacttttttg aaagattacc ctgctcggaa gccgtacttc caagcatcta
    21961 tataagaatt aagtgcccct tgcctcatat agggagcaaa ttctctataa tataaccatc
    22021 tactatatcc atcttcccaa acagcaagac cacctgaagt ttgctccaag tcctcagttg
    22081 aaagaactgt aaatgtattt gtacctgtca ttgcaagtac cttcttaaaa tatagtgatt
    22141 tgaaataaga tgtgaacaac tctatcagga aagtcaaatt aatttataga aatattttag
    22201 cagccaaggt gtactgttat agattcaata cactataaat ttttgtaagc ttacatctac
    22261 agtatacatc ttttttgtct attttatagc ccatctcctc aactgtcaat ttttcaacct
    22321 gaattgcatt tttccataaa aaatgagacc tttctagtct catttagtca ttcttagtat
    22381 tttctaaatc gttgatagcg ttcttccagc aactcttcta gcggtttttg tgaaagtcta
    22441 gccagctccg tttggagttc ttttttgaca ctcttaatca gttctttact agaaagtcct
    22501 acttcagaaa tcaccttatc caccacgtcc atttctaaca gttcatgcga agtgattttc
    22561 atcagttctg ctgcttccat ggcgcgagta ccgtccttcc ataaaatgga agcaaagcct
    22621 tctggactga gaatggcata gatagaattt tccagcatcc agacacggtc cgcgacagct
    22681 agagccagag ccccgcctga accaccttca ccgataataa tggcgataat aggaactttc
    22741 aggtcactca tttccatgag attgcgagcg atagcttccc cttgaccacg ttcttccgct
    22801 ccgacaccag gataagcacc tgctgtgttg ataaaggtca caactggacg gccaaatttc
    22861 tcagcctgtt tcatcaaccg cagtgccttt cggtagcctt ctggatgtgg ttggccaaaa
    22921 ttccgtttga ggttgtcttg caaactcttg cctttttgga taccaaccac tgttacagct
    22981 tggtctccaa gccaaccaat accaccaaca actgcaccat catcacgaaa agaacggtca
    23041 ccatgtaatt ggataaattc atcaaaaatg cctgtcgcaa agtccaaggt tgtcaagcga
    23101 ctctgctcac gcgcttctct gactattttt gcaatattca tctaggactc cctccatgca
    23161 atctgactag gctagcaatc gtatctggta agtctcttct tttgacaata gcatccacaa
    23221 agccatgttc taataggaat tctgcctttt ggaaatcctc aggcaagctt tcacgaaccg
    23281 tattttcaat cacacgacgc ccagcaaaac caaccaagct ctgtggttca gccagaatga
    23341 tatcgccttc catagcgaaa gatgctgtca caccaccagt cgttggatct gtcaaaatgg
    23401 tcaggtaaaa gagaccagca tttgaatggc gtttaaccgc cgcagagatc ttagccatct
    23461 gcatgagact catgattcct tcctgcatac gggctccacc agaggctgtg aataggacaa
    23521 ctggcaattt ttcgacagtc gcatactcaa acaaacgagt gattttttca cctacaaccg
    23581 tacccataga agccatgata aagttagaat ccataatccc aagagccaca gtctgacctt
    23641 taataagagc agttcctgtc acaacggctt catgcagacc tgttttttca cgcatagatg
    23701 ccagtttctt ttggtaacca gggaaatgca agggatcctt gctttcaatc cctgtaaaca
    23761 attctttgaa ggttcccata tcaatcgtca aagccaagcg ttcttgggca gaaatacgaa
    23821 aggtatagct acagtgcgga cagatacgtt cacttcccag atccttctga tagatggtat
    23881 gcttacagcc tggacactgg gaaaataatt catctggaac ctctggctta gcttgaggtt
    23941 tttccctaac cgaacgattg ggattgattc gaatatactt atctttttta ctaaatagag
    24001 ccattgattc cccttttcgg tttaaactct taaagtcatt ttattctttt tcttgatatt
    24061 taggtaagaa ggtttccatc aagaaggaag tatcataatc cccagcaatg acattgcgat
    24121 ctgaaatgag gtcaagctgg aaatctgcat tagtctgcac tccttcaatc tctaattcat
    24181 agagggcacg ttgcattttc atcaaggcgt caaaacgatt ttcgccgtgt actatgattt
    24241 tggcaatcat actatcataa taaggcggaa tggtataacc tggataaact gctgaatcca
    24301 cgcgcaagcc aactccacca cttggcagat agagattagt aatcttacct ggacttggag
    24361 caaagttaaa ggctgggttt tctgcattga tacgacactc gatggcatga ccacgtagga
    24421 caatatcttc ttgcttaaca gacaaaggct gacctgccgc aatgcaaatc tgttccttaa
    24481 cgatatcaac acctgaaaca aactctgtta ctggatgttc tacctgaaca cgagtattca
    24541 tctccatgaa atagaaattg ctacttgctt catcaagaag aaattcaatg gttcctgcat
    24601 tctcatagcc aacaaactct gccgctcgaa cagcagcagc acctatttca tgacgcagcg
    24661 tttttccgat tgcaatcgag ggactttctt ccaaaacctt ttggttattc ctttgaagag
    24721 aacaatcccg ttcacccaag tgaatcacat gtccatgctc atcacctagg atttgaacct
    24781 caatgtgccg agctggatag ataacccgtt ctatgtacat ggcaccattg ccataattgg
    24841 ccttggcctc actagaggca gtttcaaagg cagaaacgag gtcatctggt ttttcaacct
    24901 tacgaatccc tttaccacct ccacctgctg aagccttgag cataacagga tagccaattt
    24961 tttcagcaac aatcaaagct tcttcagagt tatgcacttc tccatctgaa cctggtataa
    25021 caggcacacc tgctttaatc atctgagcac gcgcattgat cttatccccc atcatatcca
    25081 taacatgacc agatggaccg ataaacttga tacctacttc ttcacacatg gtcgcaaatt
    25141 tggaattttc actgagaaat ccaaaaccag ggtgaatagc ttctgcctca gtcaagactg
    25201 cagctgatag aactgcatta atattgagat aagactctgt tgccttgcca ggaccaatac
    25261 aaactgcttc atctgccaaa agcgtatgaa gagcttcctt atcagcagtt gaataaaccg
    25321 ctaccgtcgc aatccccaat tcacgtgccg cacggataat acgaaccgca atttcaccac
    25381 gattggcaat taaaattttt cgaaacatgg agaacctcct tagttcccaa ttgcaaaagt
    25441 aagggtacca ctggctgcaa gcttgccatc cacttcagcc tttgcttcaa ccacagctat
    25501 ggtgccacga cgttttacaa aagtcgctgt cataaccaat tggtcgcctg gtacaacttg
    25561 cttcttaaac ttaaccttgt ccataccagc gtaaaagacc agttttcctt tattttcagg
    25621 ttttgataac tccaacacac cggcagtttg cgccaaggct tccataatca gaacacctgg
    25681 cataactggg tattgaggaa agtggccgtt aaagaaaggc tcgttgatgg tcacattttt
    25741 gatagcaaca atggtatcct cgctcacttc caagacacgg tccactagaa gcataggata
    25801 acggtgggga agggcttctt tgattccttg aatatcgatc atttgatacg taccaatcct
    25861 ttaccaaact caaccatttc ttcgttagag acgagaattt ccgttaccac accatcctta
    25921 ggagctggga tttcattcat gactttcatg gcttcgataa ttaccaatgt ttgacctttt
    25981 ttgacactat caccaactgt aacgaaggca ggtttatctg gtccagcagc caagtaaacc
    26041 actccaacaa gtggactctc tacaagattt ccctcagtag ccacacttgc ttcagctgga
    26101 gctggaactt cttctgctac agtctctgct ggagcagatg taggagctac tggactcggt
    26161 gttgctagaa cgggtgctgg agcgacttga gttgcaactt caggcacagg tctcgcttca
    26221 ttcttgctaa actgcaactc atccgtccca tttttataag aaaattctct caaacttgac
    26281 tggtcaaatt gagtcatcaa gtctttaata tcgtttaaat tcatacttat ctattctccc
    26341 aacgtttgaa agcaagaact gcattgtggc ctccaaaacc aaaagtattt gaaatagcgt
    26401 atggaatttc tttctccaag ccttgtccat aaacgacatt agcttcgata taatctgata
    26461 cttcacttgt cccagctgtc attggtacaa agttatgacg catagcttcg atggtgacga
    26521 tagcttctac tgcacccgca gcccccagca aatgtcctgt aaaagacttg gttgatgata
    26581 caggtacttc cttaccaaga acagctacga tagctccact ttctcctttt tcattggcag
    26641 gagttgacgt tccgtgagca ttgacatagg ctacttgctc tggagaaatc tcagcttctt
    26701 ccaaggctag tttgatggcc ttgacagctc cctgaccttc tggatgtgga gaagtcatgt
    26761 ggtaggcatc acaagtattt ccgtaaccaa ccacttcagc caggatagta gctccacgtt
    26821 tttcagcgtg ttcaagactt tctaaaacca acatccctga accttcaccc ataacaaacc
    26881 cattgcgatc cttatcaaat gggatcgaag cacgagttgg atcctctgta gtagagagag
    26941 ctgttaaggc ttggaaacca gcgatggcaa aaggtgtgat agaagcttct gttcctccca
    27001 ccaacatcac atcttggaaa ccaaacttaa tggagcggaa ggcatcccca atcgcatcat
    27061 ttgatgaaga gcaggcagta ttgatagatt tacaaacacc gtttgcacca aaacgcatgg
    27121 ctacattccc agaagccata tttggtaaag cttttggaag agtcattggt ttgacacgtt
    27181 tgggtccttt ttcatgaagg cgaagtacct gatcttcaat ttccttgatt ccaccaatac
    27241 cagatgcaac gataacacca aaacgatccc tattaagagc ctctacatca agattggcat
    27301 gatttacagc ctcttgggct gcatacaagg catataaaga atagttatca aaacggttgg
    27361 tatctttttt tacaaagtat ttatcgaacg gaaaatcttg gatttctgcc gcattatgca
    27421 catcaaagtc actatgatca aattttgtaa tgccaccaat gccgattttc ccagttgcta
    27481 aactattcca aaattcttct ggtgtatttc cgattggaga tgttactcca taacctgtta
    27541 ccactactcg atttagtttc attcttttca cctctagctt tcgctacata cttaagccac
    27601 catcaatggc aatcacttga ccagttagat aatcttggcc tgctaaaaat actgtcaaat
    27661 ctgcaacctg ctctgcctgc ccaaattctt tcatcggaat ctgagctagt gtagcttcct
    27721 taatcttatc tgataagata gctgtcatat cagactcaat cattcctgga gcaatcacat
    27781 tgactcgtat attccgacta gcgacctcgc gtgccacaga cttggtaaag ccaatcaagc
    27841 cagccttaga agcagcatag ttagcttgac caatattccc catcaaacca acaacactag
    27901 acatattaat gatagcacct tctctggctt tcatcatcgg tttcaagact gattgtgtca
    27961 tattaaaggc accagtcaga ttgaccttga gcactttttc aaaatctgct tctgtcatct
    28021 tgagcataag agtatcttgg gtaatccctg cattgttgac caaaacatct actgaaccca
    28081 gttctgcaat agcttgatca atcatacgct tagcgtctgc aaaatctgat acatctcctg
    28141 aaatgggaac caccttgata ccatagtttg aaaactcagc gagcaattct tctgagattg
    28201 ccccacgact gtttaagaca atgttggctc ctgcttgagc aaacttgtgg gcgatggcaa
    28261 gaccaattcc acgactcgaa cctgtaataa agatattttt atgttctagt ttcatttttt
    28321 tcctttcaaa acttctactt attttagtct atttttctaa aagtgctact aaactcgctt
    28381 gatcttccac atgagctaag tgagcagttt gatcaatttt tttaacaaaa cctgacaaga
    28441 ctttccccgg tccaatctcg ataaagttgc ttatgcctgc ttcttgcatg accccaatac
    28501 tttcatagaa acgaacgggt tccttgacct gacgcgtcaa gagctgagca atgtcctctt
    28561 tttgcatcac agcagcttct gtattgccga ctaggggaca agtaaaatct gaaaaactta
    28621 cctgagctag agtttcagct agtttctggc tagctggctc aaggagagcg gtgtgaaagg
    28681 gacctgacac cttaagagga atcaagcgtt tggcacctgc ttcttgcaaa agttcaaccg
    28741 ctcgatcaac tgcaaccact tctccagcaa tgacgatttg tgcaggtgtg ttatagttgg
    28801 ctggagtaac cactccaagt tcagaagctt tttgacaggc ttcttcaatg acctctactg
    28861 gcgtattgag aactgctacc atcttgccag agtcagcagg agccgcttct tccatatagg
    28921 ctccacgctt agctaccaag gcaaccgcat cttcaaaatc caaggcgccg cttgccacca
    28981 aggcagagta ttctccaaga gacaaaccag caaccatatc aggctgatag cccttttctt
    29041 gcaataaacg gtagatagca accgaagtcg ctagaatggc tggttgcgta tagcgggtct
    29101 gattgagttt gtcttcttcc gtatcgatga gataacgcaa atcataacct agcacctgac
    29161 tcgctcgatc aatcgtttct ttaacaatcg gatactgatc atagaaatcc cgtcccatcc
    29221 ctagatactg ggcaccttga ccagcaaata aaaaggctgt tttagtcatt tcttacaact
    29281 cctgcccagc gagaggcttc ttcttgaatt ttcttagcgg ctccgtaata caaatctttt
    29341 aggatttctt cagctgtttc ttctttagaa acaagccctg cgatttgacc tgccataaca
    29401 gagccaccat ccacatcacc gtgaacaact gctttggcta gagcacctgc tcccatttgt
    29461 tcaaagattt ctaaatcagg atcttcctgc ttaaaggcat ctttttcagc cagttcaaaa
    29521 tctctagtca actgattttt aatagcacga acagcatgac caaagtgctg agctgaaatc
    29581 gtagtatcaa tatcccttgc ttttaaaatt ttctccttgt agtttggatg ggcattcgac
    29641 tcttttgcaa ctacaaaccg tgtccccacc tgtacagcct ctgcacctag cataaagcca
    29701 gccgcagcac cttcaccatc cgcaattcct cctgcagcaa taacaggaat agatatagct
    29761 gtggctacct gtcgcaccaa ggtcatggtt gttaatttac cgatatgccc cccagcttcc
    29821 attccttctg caataacagc gtctgcaccg attttttcca tgcgtttagc taaagcgaca
    29881 ctaggaacaa caggaataac gattatccca gcttcatgga aacgttccat atacttgctt
    29941 ggatttcctg ctcctgttgt gacaacttta acaccttctt caataacgag atccacgatg
    30001 tcttccacaa agggagataa gagcatgatg ttgaccccaa agggtttatc agtcaatgat
    30061 ttgattttat caatattagc cttgacaact tctttcgggg catttccccc accgataatt
    30121 cctaatcctc cagccttgga aacagcccct gccaaatcac catcagcaac ccaggccatc
    30181 cctccttgga aaataggata gtcaatcttc aataattctg taatacgcgt tttcatagtg
    30241 cctccaacct tccttgctta cgtaatagtt cgatttcacc ataatttgac agtcaaacta
    30301 ttacctaaac aagagggagt gggtttctcc ctactccttc tactaatatt ctgcttattt
    30361 tgcttgctct tcaacgtaag caaccaagtc accaactgtt ttcaagtcat tttctgcttc
    30421 gatttggata tcaaaagcat cttcgatttc tgagattact tggaacaagt ccaatgaatc
    30481 tgcgtccaaa tcatcaaaag ttgattcaag tgttacttct gatgcgtctt ttccaagttc
    30541 ttcaacgata atttcttgta ctttttcaaa tactgccatg ataggactcc tttaaaataa
    30601 atagtttttt tataacaatg tgttcaccac atgattacct aaattgtaag aatgagcgtg
    30661 ccccaggtca agcctccacc gaagcctgat agaagaacag tctggctacc atctaaaggg
    30721 atgagacctt gttctacaca ctctgaaagt aaaatcggga tactggctgc actggtattg
    30781 ccatattcca tcatattggc tggaagtttg gctcggtcaa caccaatttt tctagccatc
    30841 ttatccaaaa tacggtcatt ggcttgatga agtagcagat aatccaagtc tgtcacctct
    30901 ataggagatt catcaatagt ctgcttgata gacttggcta catctcgaat ggcaaaatca
    30961 aagactgtgc gtccatccat cttcaaaaac gaatctgcac tttcttgatc tgaaaatgga
    31021 gaatgcaaac ctgaatgccc ataagttaaa cactcgctgc gacttccatc gctattgaga
    31081 ctctcagcta agaaatgctc ttgctcgcta gcttctaaca agacaccacc agcaccatct
    31141 ccaaacaaca cagctgttga tcgatccgac caatcgactg ccttagagag ggtttcacta
    31201 ccaatcacca agcctttttg aaagtgacca gaagcgatga acttttcagc agttgaaaga
    31261 gcaaatacaa atccactgca agccgcggtt aagtcaaaag caaaggcttt attagcacca
    31321 atattagctt gaacacgagc agctgtagag ggcatcatcg aatctggagt aatggtagct
    31381 aggatgataa aatccagttc ttctcctgtt attccagctt ttgccatcag tttcttagca
    31441 acctctgtag ccaaatcact ggtagattct gttcttgaaa tatgcctttg tcgtattccc
    31501 gttcgacttg aaatccactc atcattggta tccataatct gagccaagtc gtgatttgta
    31561 accacttgct ctggcacata atgagcaacc tgacttattt ttgcaaaagc cattatttca
    31621 aatcctccaa aaattggtaa agattagtca agcctttacc catgacagca atttcttcct
    31681 cgctcatgcc atcaataatt ttttctacca tggccttgtg gaagcgttta tgcagtctat
    31741 gaatcaagcg acccttcttt gtcaaatgca gatgcaccac acgacgatcc tgttctgacc
    31801 gaactcgctc aatgtagccc ttacgctcta aattgttcaa acttgtcgta acagttccaa
    31861 gagttaccat caactctttt gacacttgac ttggagtcac atctggagcc ttaccgatga
    31921 catcaatcgt atgcatttct ttgatggaga tatccttaaa acgactacct ctcaagttca
    31981 cttcctcaat tacaaggaca ttgttaaata tagatgttaa atattcattg attcgttggt
    32041 agtccatttt tcatatccct ccttcttcaa aaaactttta caatcaaaac atttgacaga
    32101 aagaattata tcaaaattca aagaatgatg caagtatttt ttattttcct gtaaatttag
    32161 gtcttcttct ctccgaatga gctcgcactc cttctttgaa atcctctgtt tgagctaagg
    32221 atttctgtag gttcaattct aaagtagcgt aaccctgcca gtctttaaat tggctctccc
    32281 aaaccaactt cttaatggca gcataggaat tacttgaagc acgtcttaat tttttaagaa
    32341 gctgttctct cgtcttttca agtttttcag cttcagaaac gcggtaaacc aacccccatt
    32401 ctagggcttt ttctgccgtt aaagcctctc ctgtcatagc taattgagca gcacgcgtca
    32461 caccgatact gcggctcaag agatgaattc cccctgcatc tggagccaaa ccaacaccaa
    32521 caaaggcttg gataaactta gccttatccg tcgccaaaca gaaatctgcc gcaacagcca
    32581 tattcgctgc ggcacctgca acagcaccgt caacttccat taaaacaggt ttggctattt
    32641 gcttgatttt ataagaaatc gtattgacca actctgcgat ttttgtcaat gatggaatat
    32701 catcctcatc cactgcccgc ttcatctcta ccaaatctcc cccaactgag aagaccttcc
    32761 cattggcatt gattaagata aaatgcacag ctggattttc ttctgccaaa gtcagagctt
    32821 ctaaaatctc ctcacacatg ggaatatgaa aaccatttgc gacctcagga cggttcaagg
    32881 taaggattgc caagtcctct tcaagctgat aaataatgtg ttccatcagg gctccttttt
    32941 attttataag cagtttatac tcttcgaaaa tctcttcaaa ccgcgtcagc ttccatctgc
    33001 aacctcaaaa cagtattttg agctgacttc gtcagtctta tttacaacct caaagcagtg
    33061 ctttgagcag tctgcggcta gcttcctagt ttgctctttg atttcattga gtgttaaatt
    33121 atttcactgt caaagtatat cttttttagg agcagaaagc aagaaaaaat cgactgaaag
    33181 tgtctcagcc gataagaaag gctcgcttta ggctagaaag catcttattt tcttcattga
    33241 aaaaagcctt tctttctgct ataatcgtat aaaatactta ctttaggagt tcttatgaaa
    33301 gttgttaaat ttggaggtag ttctcttgcc tctgctagtc aattagaaaa agttttaaac
    33361 atcgtcaaaa gcgattcaga gcgtcgtttt gtagtcgttt ctgcgcctgg taaacgcaat
    33421 gctgaagata ctaaggttac ggatgccctg attaaatact accgcgacta tgttgcgggt
    33481 aacgatatta gcaagagcca aagctggatt atcgaccgct atgctgctat ggttagtgaa
    33541 ttgggactaa aaccagctgt gctagaaaaa atttctaaaa gtattcacgc cttggccact
    33601 cttcctattg aagaaaatga atttctctac gatactttcc tagcagccgg tgaaaataac
    33661 aatgccaaat tgattgctgc ctactttaac caaaatggta tcgatgcacg ctatatgcac
    33721 cctagagaag ctgggattgt ggtcacaagt gaacctggtc acgctcgcat cattccatca
    33781 agttatgaca agattgaaga attgacaaac accaatgaag tccttgtcat tcctggtttc
    33841 tttggtgtca ctaaggaaaa tcaaatctgt actttctcac gtggaggttc tgatattaca
    33901 ggttctatca ttgctgctgg tgtcaaagct gacctctatg aaaactttac ggacgttgat
    33961 ggtatctttg cagcccaccc tggtattatc caccaaccac actcgattcc tgagttgacc
    34021 taccgtgaaa tgcgcgagtt ggcctatgca ggcttctcag tccttcatga cgaggctctt
    34081 cttcctgcct accgtggaaa aattcctctg gttatcaaga ataccaacaa ccctgaccat
    34141 ccaggtactc gtatcgttct aaaacacagt aatgatgaat ttccagttgt gggaattgct
    34201 ggtgactcag gctttgtcag cattaacatg tcgaaatacc tcatgaaccg tgaggttgga
    34261 tttggccgca aggttctgca aatcctggaa gaacttaaca tcggttggga acatatgcca
    34321 acaggtatcg acgatctttc tatcattctc cgttctcgcc aactaactcc catcaaggaa
    34381 gaagaaatcc tgcgtcagtt ggttcaaaag gctaaagtag atcatgcaga aatcgaacac
    34441 gacctttcta tcattatgat tgttggtgaa aaaatgaaga gccacatcgg agtgactgct
    34501 actgcgacac gcgctctatc tgaaaacaaa atcaacatcc agatgatgtc tcaaggttct
    34561 agtgaagttt ctattatgtt tgttgtcaat aaagaccaag agaaagcagc aattaaagcc
    34621 ctctacaatg ccttttttgg agaaagtaag gaagactaag catggcccaa tcacttaaca
    34681 aaacagtact cctcagtacg acaggcactt cctacctctc tatcgctggg aaagttggga
    34741 aattccttgt cggagatcag gctttggaat tttacccaga tgtcaatgtc gaacaattta
    34801 tccagattcc ttggagccat atcaatcaga ttggagccaa tgtcactgga cgcaaaatca
    34861 gccgccactt cgaagtcttt acagacaaag gaaaattcct ctttgcttca aaagactcag
    34921 gtgccattct caaaattgca cgcaaaaaac taggcaatga caaggtcgtc aaacttccga
    34981 ccctgattca gacaattagc caaaaattta aaaatctatt tgcaaaaaag tagaaacttt
    35041 agtataatca tagcaacgga taagtaggtt atcttcttct ttcagaaagt ctgcgggtac
    35101 tgcgagcaga taggagggat aggtgaaatt ctaccgttag taacaattac atacacaatc
    35161 aagtgcacac ctgtgaagtt ggatggaacc gtggccctgc cactccaacg ttttgtcagg
    35221 cgtgcttttt tcataaagga gttcttatgt tagatatcaa acgtattcgt acagattttg
    35281 aagctgtcgc agaaaaatta gctacacgtg gtgtagatgc tgctgtcttg aatgaaatga
    35341 aaaaaatcga tgctaaacgt cgtaacatct tggtcaaggt tgaaactctc aaagcagaac
    35401 gtaacacagt ttctgctgag attgcccaag ctaagcgcaa caaggaaaat acagatgaca
    35461 agattgctgc catgcaaaat ctatctgctg aggttaaagc cttggatgct gaattggcag
    35521 aaatcgatgc taaattgaca gaatttacaa cgactcttcc aaatatccca gctgacagcg
    35581 ttcctgttgg ggctgacgaa gacgacaatg tggaagttcg ccgttggggt actccacgcg
    35641 agtttgactt cgaacctaaa gctcactggg atctcggtga agaccttggt atccttgact
    35701 gggaacgcgg tggtaaggta acaggcgctc gcttcctctt ctataaaggc ctcggtgctc
    35761 gtttggaacg tgctatctac aactttatgt tggatgaaca tggaaaagaa ggctatactg
    35821 aagtcatcac accttacata gtcaaccatg attctatgtt tggtactggt cagtatccaa
    35881 aatttaagga agatactttt gaactcagcg ataccaactt tgtcttgatt ccaactgctg
    35941 aagttcctct gacaaactac taccgtgatg aaatcttaga cggcaaagat cttccaatct
    36001 acttcactgc tatgagtccg tcattccgtt ctgaggctgg ttctgccggt cgtgatacgc
    36061 gtggcttgat ccgtttgcac caattccaca aggttgaaat ggtcaaattt gccaaaccag
    36121 aagaatctta cgaagaattg gaaaaaatga cagccaacgc tgaaaacatt cttcaaaaac
    36181 tcaaccttcc ataccgtgtc gttgctctct ctactggaga tatgggcttc tcagctacga
    36241 agacttacga cttggaagtg tggattccag cacaaaacaa ttaccgtgaa atctcaagct
    36301 gttcaaacac agaagatttc caagcccgtc gtgcccaaat ccgttaccgt gatgaagcag
    36361 atggcaaggt gaaactcctt cataccttga acggttctgg acttgcagtt ggacgtacag
    36421 tggctgcaat tcttgaaaat taccaaaatg aagatggttc tgtgaccatc ccagaagcac
    36481 ttcgtccata catgggtgga gctgaagtca tcaaaccata aaaa
//
LOCUS       DAVLXH010000017        35713 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00028199
            SAMN33607166-rid17955573.denovo.017, whole genome shotgun sequence.
ACCESSION   DAVLXH010000017 DAVLXH010000000
VERSION     DAVLXH010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607166
            Sequence Read Archive: SRR23725544
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 35713)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35713)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721421.1
            Genome Coverage       :: 115x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:42:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,210
            CDSs (total)                      :: 2,161
            Genes (coding)                    :: 2,023
            CDSs (with protein)               :: 2,023
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 73 of 138
            Pseudo Genes (incomplete)         :: 60 of 138
            Pseudo Genes (internal stop)      :: 40 of 138
            Pseudo Genes (multiple problems)  :: 31 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35713
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607166-rid17955573.denovo.017"
                     /strain="AUSMDU00028199"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1349"
     gene            complement(174..1808)
                     /locus_tag="VYO11_000925"
     CDS             complement(174..1808)
                     /locus_tag="VYO11_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001237556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1595514.1"
                     /translation="MRLKVIKKLVDINILYSSQEANLANLRKKQAKNPGKKVNVSARV
                     LSSYIFSSLLMLICFSNIAIHFPFEEIPIYFSSMVAILLVLAFSTSFTAFYNVFYESK
                     DLASYRPYAFKESEIIMAKGLSVLLPALAGIVPILAYFLVLYIRLAPSLWLGLPLMLL
                     SLTLLFVSVTLVMVVAVHFLAQTTVFRKYQSIFSNVMIGIGVLIPLIFIFFLQSTFGS
                     IVDKVRDIPFLLYPLHIFYKIAVEPFSTEAILGLLAWIGLTLFLLYLTKKKVLPRFYD
                     VILLNSEEKVKKERRSKERISTTKKGFFRMVLRYHLTLLGQGTGVVTVLFTSAFFPYL
                     MMIGLISKIRDSQIVPDIHPPYWLPLFFVGVFIAVVNNNITSLHSIALSLERENVDFL
                     KSLPFDFARYVKVKFWIIYAVQSFLPVLTLLGLSLYLGLPIISMIYLIVAWILASVIL
                     SCHHYFKDVKNLSTNWSSITDLVNRSNGIVAIVLLFIYSAILMALVIGSIFLVQSLST
                     ILAISLGVGALILLLALAIFGYHYYLSRILAEIEKR"
     gene            complement(1789..2538)
                     /locus_tag="VYO11_000926"
     CDS             complement(1789..2538)
                     /locus_tag="VYO11_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1595515.1"
                     /translation="MIEFQNVSKLYGDKKALSNLNLQIENGEIMGLIGHNGAGKSTTI
                     KSLVSIISPSSGRILVDGQELSENRLAIKRKIGYVADSPDLFLRLTANEFWELIASSY
                     DLSRSDLEASLARLLNVFDFAENRYQVIETLSHGMRQKVFVIGALLSDPDIWVLDEPL
                     TGLDPQAAFDLKQMMKEHAQKGKTVLFSTHVLEVAEQVCDRIAILKKGHLIYCGKVED
                     LRKDNPDQSLESIYLSLAGRKEEVSDASQGH"
     gene            2717..4171
                     /locus_tag="VYO11_000927"
     CDS             2717..4171
                     /locus_tag="VYO11_000927"
                     /EC_number="3.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase"
                     /protein_id="HEV1595516.1"
                     /translation="MQNQTLMQYFEWYLPHDGQHWTRLAENAPHLAHLGISHVWMPPA
                     FKATNEKDVGYGVYDLFDLGEFNQKGTVRTKYGFKEDYLQAIQALKAQGIQPMADVVL
                     NHKAAADHREAFQVIEVDPVDRTVELGEPFTINGWTSFTFDGRQDTYNDFHWHWYHFT
                     GTDYDAKRRKSGIYLIQGDNKGWANEELVDNENGNYDYLMYADLDFKHPEVIQNIYDW
                     ADWFMETTGVAGFRLDAVKHIDSFFMRNFIRDMKEKYGDDFYVFGEFWNPDKEANLDY
                     LEKTEEHFDLVDVRLHQNLFEASQAGANYDLRGIFTDSLVELKPDKAVTFVDNHDTQR
                     GQALESTVEEWFKPAAYALILLRQDGLPCVFYGDYYGISGQYAQEDFKEILDRLLAIR
                     KDLAYGEQNDYFDHANCIGWVRSGAENQSPIAVLISNDQENSKSMFVGQEWTNQTFVD
                     LLGNHQGQVTIDEEGYGQFPVSARSVSVWAVNTI"
     gene            complement(4261..6879)
                     /gene="alaS"
                     /locus_tag="VYO11_000928"
     CDS             complement(4261..6879)
                     /gene="alaS"
                     /locus_tag="VYO11_000928"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HEV1595517.1"
                     /translation="MKQLSSAQVRQMWLDFWATKGHSVEPSVSLVPVNDPTLLWINSG
                     VATLKKYFDGTIIPENPRITNAQKAIRTNDIENVGKTARHHTMFEMLGNFSIGDYFRD
                     EAITWAYELLTSPEWFDFPAEKLYMTYYPDDKDSYNRWIEVGVDPSHLIPIEDNFWEI
                     GAGPSGPDTEIFFDRGEAFDPENIGLRLLAEDIENDRYIEIWNIVLSQFNADPAVPRS
                     EYKELPHKNIDTGAGLERLVAVIQGAKTNFETDLFMPIIREVEKLSGKVYDQDGDNMS
                     FKVIADHIRSLSFAIGDGALPGNEGRGYVLRRLLRRASMHGQKLGINEPFLYKLVPTV
                     GKIMESYYPEVLEKRDFIEKIVKSEEESFARTLHSGQHFAQGIVADLKEKGQSVIAGQ
                     DVFKLYDTYGFPVELTEEIAEEAGMTVDREGFEAAMKEQQERARASAVKGGSMGMQNE
                     TLQNITVESVFNHNASQLSSKLVAIVADNAEVEAVSEGTTSLIFAETPFYAEMGGQVA
                     DHGQILDESGKVVATVTNVQKAPNGQALHTVEVLAPLALNQEYTLAIDSNRRHRVMKN
                     HTATHLLHAALHNILGNHATQAGSLNEVEFLRFDFTHFQAVTAEELRAIEQQVNEKIW
                     EALEVKTVETDIDTAKEMGAMALFGEKYGKEVRVVTIGDYSIELCGGTHVGNTSEIGL
                     FKIVKEEGIGSGTRRILAVTGKEAFEAYREQEDALKAVAATLKAPQVKEVPHKVEGLQ
                     EQLRQLQKENAELKEKAAAAAAGDIFKDVKEVNGHRYIASQVSVSDAGALRTFADNWK
                     QKDYSDLLVLVAAIGDKVNVLVASKTKDLHAGNLVKELAPIIDGRGGGKPDMAMAGGS
                     NQPKIQELLDAVAGKL"
     gene            complement(6901..7386)
                     /locus_tag="VYO11_000929"
     CDS             complement(6901..7386)
                     /locus_tag="VYO11_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000847073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LURP-one-related family protein"
                     /protein_id="HEV1595518.1"
                     /translation="MKTFLVKQKFRLGGERFAIKDDRGEIAYQVEGSFFKIPKTFTIY
                     DAAGEQVSEISKEILTLLPRFEIQLRDGSSFVIRKKLTFWRDKYEFDNLGLRIEGNIW
                     DLNFKLLDDRDQLIAEIKKELFHLTSTYTVTVLEDAYADLVISLCVAIDYVEMLESQS
                     H"
     gene            complement(7661..7900)
                     /locus_tag="VYO11_000930"
     CDS             complement(7661..7900)
                     /locus_tag="VYO11_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000784186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1595519.1"
                     /translation="MKMSTFFKKSFWPTFMIVNQTVILSHLKDGLDRQYLTTESIYWV
                     IGTFIFGNILVAVFSNMKIWDKKKNGSKKKYILKK"
     gene            complement(8145..9215)
                     /locus_tag="VYO11_000931"
     CDS             complement(8145..9215)
                     /locus_tag="VYO11_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEV1595520.1"
                     /translation="MKKIYSFLAGIAAIILVLWGIATHLDSKINSRDSQKLVIYNWGD
                     YIDPELLTQFTEETGIQVQYETFDSNEAMYTKIKQGGTTYDIAIPSEYMINKMKDEDL
                     LVPLDYSKIEGIENIGPEFLNQSFDPGNKFSIPYFWGTLGIVYNETMVDEAPEHWDDL
                     WKPEYKNSIMLFDGAREVLGLGLNSLGYSLNSKDPQQLEETVDKLYKLTPNIKAIVAD
                     EMKGYMIQNNVAIGVTFSGEASQMLEKNENLRYVVPTEASNLWFDNMVIPKTVKNQDS
                     AYAFINFMLKPENALQNAEYVGYSTPNLPAKELLPEETKEDKAFYPDVETMKHLEVYE
                     KFDHKWTGKYSDLFLQFKMYRK"
     gene            complement(9212..9985)
                     /locus_tag="VYO11_000932"
     CDS             complement(9212..9985)
                     /locus_tag="VYO11_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1595521.1"
                     /translation="MKKFANLYLGLVFLVLYLPIFYLIGYAFNAGDDMNSFTGFSWTH
                     FETMFGDGRLMLILAQTFFLAFLSALIATIIGTFGAIYIYQSRKKYQEAFLSLNNILM
                     VAPDVMIGASFLILFTQLKFSLGFLTVLSSHVAFSIPIVVLMVLPRLKEMNGDMIHAA
                     YDLGASQFQMFKEIMLPYLTPSIITGYFMAFTYSLDDFAVTFFVTGNGFSTLSVEIYS
                     RARKGISLEINALSALVFLFSIILVVGYYFISREKEEQA"
     gene            complement(9982..10788)
                     /locus_tag="VYO11_000933"
     CDS             complement(9982..10788)
                     /locus_tag="VYO11_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1595522.1"
                     /translation="MKKTSSKLFVVPYMLWIALFVLAPLVLIFGQSFFNIEGQFSLEN
                     YKSYFASQNLTYLKMSFNSVLYAGIVTFVTLLISYPTALFLTRLKHRQLWIMLIILPT
                     WINLLLKAYAFIGIFGQNGSINQFLEFIGIGSQQLLFTDFSFIFVASYIELPFMILPI
                     FNVLDDMDNNLINASYDLGATKWETFRHVIFPLSMNGVRSGVQSVFIPSLSLFMLTRL
                     IGGNRVITLGTAIEQNFLTNDNYGMGSTIGVILILTMFITMWVTKERRER"
     gene            complement(10769..11926)
                     /locus_tag="VYO11_000934"
     CDS             complement(10769..11926)
                     /locus_tag="VYO11_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018372333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1595523.1"
                     /translation="MKKSIIEFKNVSKVFEDSNTKVLKDINFELEEGKFYTLLGASGS
                     GKSTILNIIAGLLDATTGDIMLDGVRINDIPTNKRDVHTVFQSYALFPHMNVFENVAF
                     PLRLRNIDKKEIEQRVAEVLKMVQLEGYEKRSIRKLSGGQRQRVAIARAIINQPRVVL
                     LDEPLSALDLKLRTDMQYELRELQQRLGITFVFVTHDQEEALAMSDWIFVMNDGEIVQ
                     SGTPVDIYDEPINHFVATFIGESNILPGTMIEDYLVEFNGKRFEAVDGGMKPNEPVEV
                     VIRPEDLRITLPEEGKLQVKVDTQLFRGVHYEIIAYDELGNEWMIHSTRKAIVGEEIG
                     LDFEPEDIHIMRLNETEEEFDARIEEYVEIEEQEAGLINAIEEERDEENKL"
     gene            complement(12087..12992)
                     /gene="murB"
                     /locus_tag="VYO11_000935"
     CDS             complement(12087..12992)
                     /gene="murB"
                     /locus_tag="VYO11_000935"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000116193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HEV1595524.1"
                     /translation="MSVREKMLEILEGIDIRFKEPLHSYSYTKVGGEADYLVFPRNRF
                     ELARVVKFANQENIPWMVLGNASNIIVRDGGIRGFVILCDKLNNVSVDGYTIEAEAGA
                     NLIETTRIALRHSLTGFEFACGIPGSVGGAVFMNAGAYGGEIAHILQSCKVLTKDGEI
                     ETLSAKDLAFGYRHSAIQESGAVVLSVKFALAPGTHQVIKQEMDRLTHLRELKQPLEY
                     PSCGSVFKRPVGHFAGQLISEAGLKGYRIGGVEVSEKHAGFMINVADGTAKDYEDLIQ
                     SVIEKVKEHSGITLEREVRILGESK"
     gene            complement(13104..13547)
                     /locus_tag="VYO11_000936"
     CDS             complement(13104..13547)
                     /locus_tag="VYO11_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007284978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhfC family intramembrane metalloprotease"
                     /protein_id="HEV1595525.1"
                     /translation="MEKADALAYGLGHGGLELIFLGLISLLNLYIVLSAVQTQNPQVM
                     QLLSENMLKTIQSLLVWQIYLLGFERILALGFQLLLTVWVYQAVRQKKWIYLLAAYGL
                     HAFFDLAPSLFQVGWLTNPVLVEVILALELVLVAYGTKEIFCKKS"
     gene            complement(13514..13855)
                     /locus_tag="VYO11_000937"
                     /pseudo
     CDS             complement(13514..13855)
                     /locus_tag="VYO11_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860802.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YhfC family intramembrane metalloprotease"
     gene            complement(13865..14596)
                     /gene="budA"
                     /locus_tag="VYO11_000938"
     CDS             complement(13865..14596)
                     /gene="budA"
                     /locus_tag="VYO11_000938"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HEV1595526.1"
                     /translation="MDKNVQEPVKLFQYNTLGALMAGLYGGTMTVGELLEHGDLGLGT
                     LDSIDGELIVLDGKAYQAKGSGDQPEIVEVSPDALIPYAAVVPHQAEVIFRQRFEMTD
                     KELKERIESYYDGENLFRSIKIRGEFSHMHVRMIPKSTPDTKFADVATHQPEYSRDNV
                     AGTIVGFWTPEIFHGVSVAGYHLHFISDDLTFGGHVMDFVIKEGIIEVGAVDQLDQRF
                     PVQDRQYLFAKFNVDEMKKDIEKAE"
     gene            14738..16009
                     /locus_tag="VYO11_000939"
     CDS             14738..16009
                     /locus_tag="VYO11_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HEV1595527.1"
                     /translation="MKKQSKYKEVVSYLKNGIESERFPTGSRLPSIRQLSLDFHCSKD
                     TIQRALLELRHEQYLYAKPQSGYYVLEQGQHQDLEIEVTDEHASAYDDFRLCVNETLI
                     GRENYLFNYYDNQEGLEDLRQSIHKLLFEQALYCKANQLVLTSGTQQALFILSQISFP
                     RQAKEILVEQPTYHRMNRLLIAQGLDYQTIERGIDGIDLEELEGHFKTGKIKFFYTIP
                     RFHYPLGHSYSEQDKRSILNLAAKYDVYIVEDDYLGDLDSKKGQTFHYLDTEERVIYI
                     KSFSTSLFPALRITALILPNAIKEAFVAYKNILDYDSNLIMQKALSLYIDSQLFEKNR
                     LARLTNHESYQKQIEERITKTPCPLPHYPLHDGLLLDLRQYPKIASLKHSQLGLDFFE
                     EAYLSTCPYQFAKVSLDNLENVLNYLKAELE"
     gene            complement(16029..16844)
                     /locus_tag="VYO11_000940"
     CDS             complement(16029..16844)
                     /locus_tag="VYO11_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEV1595528.1"
                     /translation="MKSKKWIFVLCNFLASFFLVACQSGSNGSQSAVEAIKQKGKLVV
                     ATSPDYAPFEFQSLVDGKNQVVGADIDMAQAIADELGVKLEISSMSFDNVLTSLQTGK
                     ADLAVAGISATDERKEVFDFSIPYYENKISFLVRKADVEKYKDLTSLESANIAAQKGT
                     VPESMVKEQLPKAQLTSLTNMGEAVNELQAGKVDAVHMDEPVALSYAAKNAGLAVATV
                     SLKMKDGDANAVALRKNSDDLKEVVDKVIQKLKDEGTYQSYLEKAASLTEVEE"
     gene            complement(17001..17654)
                     /gene="phoU"
                     /locus_tag="VYO11_000941"
     CDS             complement(17001..17654)
                     /gene="phoU"
                     /locus_tag="VYO11_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000946475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HEV1595529.1"
                     /translation="MLRSQFEEDLEKLHNQFYAMGQEVLSQINRTVRAFVTHDRDLAK
                     EVIEDDAEVNEYEVKLEKKSFEMIALQQPVSQDLRTVLTVLKAVSDVERMGDHAVAIA
                     QATIRMKGEERIPAVEEEIKKMGREVKSVVEAALDLYLNGSVDDAYRVASMDEQINHY
                     FETIRDLATEEIKKNPEAIVTGRDYFQVISYLERIGDYAKNICEWVVYFETGKIVEL"
     gene            complement(17666..18424)
                     /gene="pstB"
                     /locus_tag="VYO11_000942"
     CDS             complement(17666..18424)
                     /gene="pstB"
                     /locus_tag="VYO11_000942"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEV1595530.1"
                     /translation="MTDAILQVSDLSVYYNKKKALNSVSLSFQPKEITALIGPSGSGK
                     STLLKSLNRMGDLNPEVTTTGSVVYNGHNIYSPRTDTVELRKEIGMVFQQPNPFPMTI
                     YENVVYGLRINGIKDKQVLDEAVEKALQGASIWDEVKDRLYDSAIGLSGGQQQRVCVA
                     RVLATSPKIILLDEPTSALDPISAGKIEETLYGLKDKYTMLLVTRSMQQASRISDKTG
                     FFLDGDLIEFNDTKQMFLNPQHKETEDYITGKFG"
     gene            complement(18437..19240)
                     /gene="pstB"
                     /locus_tag="VYO11_000943"
     CDS             complement(18437..19240)
                     /gene="pstB"
                     /locus_tag="VYO11_000943"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEV1595531.1"
                     /translation="MSTYNWDEKHILTFPEEKVALSTKDVHVYYGKNESIKGIDMQFE
                     RNKITALIGPSGSGKSTYLRSLNRMNDTIDIAKVTGQILYRGIDVNRPEINVYEMRKH
                     IGMVFQRPNPFAKSIYRNITFAHERAGVKDKQVLDEIVETSLRQAALWDQVKDDLHKS
                     ALTLSGGQQQRLCIARAISVKPDILLMDEPASALDPIATMQLEETMFELKKNFTIIIV
                     THNMQQAARASDYTGFFYLGDLIEYDKTATIFQNAKLQSTNDYVSGHFG"
     gene            complement(19251..20135)
                     /gene="pstA"
                     /locus_tag="VYO11_000944"
     CDS             complement(19251..20135)
                     /gene="pstA"
                     /locus_tag="VYO11_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009443446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HEV1595532.1"
                     /translation="MRAKKLDKLATAVLYTIASIIVTILASLILYILVRGLPHISWSF
                     LTGRSSAFQAGGGIGIQLYNSFFLLVITLIISVPLSMGAGIYLAEYAKKGPVTNFVRT
                     CIEILSSLPSVVVGLFGYLIFVVQFEYGFSIISGALALTVFNLPQMTRNVEDSLKHVH
                     HTQREAGLALGISRWETVVHVVIPEALPGIVTGVVLASGRIFGEAAALIYTAGQSAPA
                     LDWSNWNILSVTSPISIFRQAETLAVHIWKVNSEGTIPDGTIVSAGSAAVLLIFILIF
                     NFGARKFGSYLHKKLTAA"
     gene            complement(20125..21042)
                     /gene="pstC"
                     /locus_tag="VYO11_000945"
     CDS             complement(20125..21042)
                     /gene="pstC"
                     /locus_tag="VYO11_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018378778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HEV1595533.1"
                     /translation="MNQEELAKKMLLPSKNSRLEKLGKGLTFACLSLIVILVAMILVF
                     VAQKGLSTFFVNGVNIFDFLLGGTWNPSSKEFGALPMILGSFIVTILSALIATPFAIG
                     AAVFMTEVSPKGAKILQPAIELLVGIPSVVYGFIGLQVVVPFVRSVFGGTGFGILSGI
                     SVLFVMILPTVTFMTTDSLRAVPRYYREASFAMGATRWQTIWRVILKAARSGIFTAVV
                     FGMARAFGEALAIQMVVGNSAVIPTSLTTPAATLTSILTMGIGNTVMGTVNNNVLWSL
                     ALVLLLMSLVFNSVIKLITKERGKKNYAR"
     gene            complement(21042..21920)
                     /gene="pstS"
                     /locus_tag="VYO11_000946"
     CDS             complement(21042..21920)
                     /gene="pstS"
                     /locus_tag="VYO11_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HEV1595534.1"
                     /translation="MKKRKKLALSLIAFWLTACLVGCASWIDRGESITAVGSTALQPL
                     VEVAADEFGTIHVGKTVNVQGGGSGTGLSQVQSGAVDIGNSDVFAEEKDGIDASALVD
                     HKVAVAGLALIVNKEVDVDNLTTEQLRQIFIGEVTNWKEVGGKDLPISVINRAAGSGS
                     RATFDTVIMEGQSAMQSQEQDSNGAVKSIVSKSPGAISYLSLTYIDDSVKSMKLNGYD
                     LSPENISSNNWPLWSYEHMYTLGQPNELAAEFLNFVLSDETQEGIVKGLKYIPIKEMK
                     VEKDAAGTVTVLEGRQ"
     gene            complement(22494..23798)
                     /locus_tag="VYO11_000947"
     CDS             complement(22494..23798)
                     /locus_tag="VYO11_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001160253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmF rRNA methyltransferase first C-terminal
                     domain-containing protein"
                     /protein_id="HEV1595535.1"
                     /translation="MKFPEGFVEKYKEILGDEARDFLASFEEEAVSAFRVNPLKEEQL
                     SFSDAITQTPWGHYGKVSGKSPEHATGLVYSQEPAAQMVAQVAQPSPGMKVLDLAAAP
                     GGKSTQLAAYLAGEGLLVSNEISSKRAKILVENMERFGATNVVVTNESADRLVKVFKG
                     YFDLIVLDAPCSGEGMFRKQPDAMDYWSLDYPSQCASLQREILEDAVTMLAEGGRLVY
                     STCTWAPEENEEIVNWLLEEYDFDLLPVEHINGMVAGIDLPETARMYPHQFKGEGQFV
                     AHLQFKGNNPAPKFKASKSNLSREQVALWQEFAQNHLKVNLPGILQIFGDQLYLLPEL
                     LPDLGKLKIARNGLHLGTFKKKRFEPSFALGLALKPSQVEQSVEIGQEAFVKYAAGET
                     VQLAESLPNGWYQVLVKGNGLGFAKVTGNVLKNYFPKGLRFK"
     gene            complement(23799..24572)
                     /locus_tag="VYO11_000948"
     CDS             complement(23799..24572)
                     /locus_tag="VYO11_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HEV1595536.1"
                     /translation="MESKFEFAKGLVKKAGQYILDHMQEDLRVETKSSPTDLVTRLDK
                     EVQELLVGEILSRYPEDKICAEEGCLRASVQEGKVWVIDPIDGTNNFVAQQEDFAVMM
                     AYFENGQGQFGLIYDVVKGDCYHGGGEFPVCLNDRPLAPFKTKPLGDFLIAGNSGMLE
                     TNEWGLADLSRAVLGVRVYGSAAISFAKILSGHLLTYLTYLQPWDYAAASILGESLGY
                     RVVTLFGEAPDFQTRQPVMMVPLEMQEEIQSYIYERKRT"
     gene            complement(24562..24840)
                     /locus_tag="VYO11_000949"
     CDS             complement(24562..24840)
                     /locus_tag="VYO11_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HEV1595537.1"
                     /translation="MNKQYSYPLDLSWSTEELASVLSFFNDVEAAYEGKVEAKKLLDS
                     YKGFKAVVPSKSEEKRLGREFETVSGYSLYRAVQAAKEKGEGKISLGK"
     gene            complement(24840..25241)
                     /locus_tag="VYO11_000950"
     CDS             complement(24840..25241)
                     /locus_tag="VYO11_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007556665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HEV1595538.1"
                     /translation="MITLFLSPSCTSCRKAKAWLEKHKVPFVEHNIMTSPLTRKELQH
                     ILSLTENGTDDIISTRSKIFQKLNIDVESISVSELLHLIEQYPSLLRRPIIIDAKRMQ
                     IGFNEDEIRAFLPRSYRKQELKEARMRAGIS"
     gene            complement(25451..26068)
                     /locus_tag="VYO11_000951"
     CDS             complement(25451..26068)
                     /locus_tag="VYO11_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HEV1595539.1"
                     /translation="MKTKLTFWGSMLFLLSLSILLTIYLAWIFYPMEIQWLNLTNRVY
                     LKPETVQYNFHILMNYLTNPFSQVLQMPDFRSSAAGLHHFAVVKNLFHLVQLVALVTL
                     PSFYVFVNRIVKKDFLSLYRKSLLALVVLPVMIGLGGVLIGFDQFFTLFHQILFVGDD
                     TWLFDPAKDPVIMILPETFFLHAFLLFFALYENFFGYLYLKSRRK"
     gene            complement(26058..26831)
                     /locus_tag="VYO11_000952"
     CDS             complement(26058..26831)
                     /locus_tag="VYO11_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HEV1595540.1"
                     /translation="MKYKGYLIDLDGTIYKGKDRIPAGETFVHELQKRDIPYLFVTNN
                     TTRTPESVKEMLAQNFNIDTPLSTVYTATLATIDYMNDLGLEKTVYVVGEAGLKEAIK
                     AAGYVEDKENPAYVVVGLDWQVDYEKFATATLAIQKGAHFIGTNPDLNIPTERGLLPG
                     AGSLITLLEVATRVKPVYIGKPNAIIMDKAVEHLGLEREELIMVGDNYLTDIRAGIDN
                     GIPTLLVTTGFTKAEEVAGLPIAPTHVVSSLAEWDFDEN"
     gene            complement(26842..27579)
                     /locus_tag="VYO11_000953"
     CDS             complement(26842..27579)
                     /locus_tag="VYO11_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HEV1595541.1"
                     /translation="MGLTYQMKMKIPFDMADMNGHIKLPDVILLSLQVSGMQSIELGV
                     SDKAILEDYNLVWIIAEYDIEVVRLPRFAEEITIETEALSYNRLFCYRRFTIYNEAGQ
                     ELIHMMATFVLMDRDSRKVHAVEPEIVAPYQSDFDKKLIRGPKYESLEEPISKDYHVR
                     FYDLDMNGHVNNSKYLDWIFEVMGADFLTHYIPKKINLKYVKEVRPGGVITSAVERTG
                     LESKHEITSDGVINAQAIITWQEIKKV"
     gene            complement(27584..28714)
                     /locus_tag="VYO11_000954"
     CDS             complement(27584..28714)
                     /locus_tag="VYO11_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HEV1595542.1"
                     /translation="MQKKPTSAYVHIPFCTQICYYCDFSKVFIKNQPVDSYLEHLLEE
                     FRSYDIEKLSTLYIGGGTPTALSAPQLEVLLNGLTKNLDLSVLEELTIEANPGDLDAD
                     KIAVLKNSAVNRVSLGVQTFDDKMLKKIGRSHLEKDIYENIDRLKLAGFDNISIDLIY
                     ALPGQTMEQVKENVAKAIGLDIPHMSLYSLILENHTVFMNRMRRGKLPLPKEELEAEM
                     FEYIIAELERAGFEHYEISNFSKPGFESRHNLMYWDNAEYYGIGAGASGYVNGVRYKN
                     HGPIRHYLSAVEEGNACITEDHLSQKEQMEEEMFLGLRKKSGVSMARFEEKFGQSFAE
                     LYGEIVRDLVQQGLMQIEGDHVRMTKRGLFLGDTVAERFILE"
     gene            complement(28798..29187)
                     /locus_tag="VYO11_000955"
     CDS             complement(28798..29187)
                     /locus_tag="VYO11_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HEV1595543.1"
                     /translation="MGKLSSILLGTVSGAALALFLTSDKGKQVCSQAQDFLDDLREDP
                     EYAKEQVCEKLTEVKEQATDFVLKTKEQVESGEITVDSILAQAKSYAFQATEASKNQL
                     NNLKEQWQEKAEALDDSEEIVIDITEE"
     gene            complement(29203..29586)
                     /locus_tag="VYO11_000956"
     CDS             complement(29203..29586)
                     /locus_tag="VYO11_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HEV1595544.1"
                     /translation="MLEVAYILVALAVIVFLVYLIITVQKLGRVIDETEKTIKTLTSD
                     VDVTLHHTNELLAKVNVLADDINVKVATIDPLFSAVADLSLSVSDLNDHARVLSKKAS
                     SAGSKTLKTGASLSALRLASKFFKK"
     gene            complement(29587..30375)
                     /locus_tag="VYO11_000957"
     CDS             complement(29587..30375)
                     /locus_tag="VYO11_000957"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HEV1595545.1"
                     /translation="MLDPIAIQLGPLAIRWYALCIVTGLILAVYLTMKEAPRKKIIPD
                     DILDFILVAFPLAILGARLYYVIFRFDYYSQNLGEIFAIWNGGLAIYGGLITGALVLY
                     IFADRKLINTWDFLDIAAPSVMIAQSLGRWGNFFNQEAYGATVDNLDYLPGFIRDQMY
                     IEGSYRQPTFLYESLWNLLGFALILIFRRKWKSLRRGHITAFYLIWYGFGRMVIEGMR
                     TDSLMFFGLRVSQWLSVVFIGLGIMIVIYQNRKKAPYYITEEEN"
     gene            complement(30368..31303)
                     /locus_tag="VYO11_000958"
     CDS             complement(30368..31303)
                     /locus_tag="VYO11_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HEV1595546.1"
                     /translation="MSVLVKEVIEKLRLDIVYGEPELLEKEINTADITRPGLEMTGYF
                     DYYTPERIQLLGMKEWSYLISMPSNSRYEVLKKMFLPETPAVIVARGLVVPEEMLKAA
                     RECKIAILTSRAATSRLSGELSSYLDSRLAERTSVHGVLMDIYGMGVLIQGDSGIGKS
                     ETGLELVKRGHRLVADDRVDIFAKDEITLWGEPAEILKHLIEIRGVGIIDVMSLYGAS
                     AVKDSSQVQLAVYLENYDTHKTFDRLGNNAEELEVSGVAIPRIRIPVKTGRNISVVIE
                     AAAMNYRAKEMGFDATRLFDERLTSLIARNEVQNA"
     gene            complement(31433..31609)
                     /locus_tag="VYO11_000959"
     CDS             complement(31433..31609)
                     /locus_tag="VYO11_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000048061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HEV1595547.1"
                     /translation="MSKTVVRKNESLDDALRRFKRAVTKAGTLQETRKREFYEKPSVK
                     RKRKSEVARKRKKF"
     gene            complement(31749..32456)
                     /locus_tag="VYO11_000960"
     CDS             complement(31749..32456)
                     /locus_tag="VYO11_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HEV1595548.1"
                     /translation="MKVIKVENQVQGGKVAFEILKEKLANGAQTLGLATGSSPLEFYK
                     EIVESDLDFSNLTSVNLDEYVGLDGDNPQSYRYFMQENLFNQKPFKESFLPRGVKDNA
                     EAEVERYNQILADHPVDLQILGIGRNGHIGFNEPGTPFDSQTHLVELDQSTIEANARF
                     FAKIEDVPTQAISMGIKNILDAKSIILFAYGESKAEAIAGTVSGPVTENLPASSLQNH
                     PDVTIIADAEALSLLEK"
     gene            32607..33635
                     /gene="queA"
                     /locus_tag="VYO11_000961"
     CDS             32607..33635
                     /gene="queA"
                     /locus_tag="VYO11_000961"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HEV1595549.1"
                     /translation="MNTADFDFHLPEELIAQTPLEKRDASKLLIVNRETGEMQDKHFH
                     SIIDMLEPGDALVMNDTRVLPARLYGQKVETGGHVELLLLKNTSGDEWEVLAKPAKRL
                     KVGTRISFGDGRLSAVVTEELTHGGRIVRFEYQGIFLEVLESLGEMPLPPYIHEKLDD
                     RERYQTVYAKESGSAAAPTAGLHFTKELLAEIQAKGVHLVYLTLHVGLGTFRPVSVDN
                     LDEHEMHSEFYQLSEEAAATLRSVKENGGRVIAVGTTSIRTLETIGSKFDGQIQADSG
                     WTNIFIKPGYEWKVVDAFSTNFHLPKSTLVMLVSAFAGRELVLDAYHHAIQEHYRFFS
                     FGDAMFIY"
     gene            complement(34296..34685)
                     /locus_tag="VYO11_000962"
     CDS             complement(34296..34685)
                     /locus_tag="VYO11_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HEV1595550.1"
                     /translation="MVKRRIRRGTREPEKVVVPEQSSIPSYPVSVTSNQGTDVAVEPA
                     KAVAPTTGWKQENGMWYFYNTDGSMATGWVQVNGSWYYLNSNGSMKVNQWFQVGGKWY
                     YVNTSGELAVNTSIDGYRVNDNGEWVR"
     gene            complement(34739..35431)
                     /locus_tag="VYO11_000963"
     CDS             complement(34739..35431)
                     /locus_tag="VYO11_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HEV1595551.1"
                     /translation="MNTSFVHAADGIQYVRDDTRDKEEGIEYDDADNGDIIVKVATKP
                     KVVTKKISSTRIRYEKDETKDRSENPVTIDGEDGYVTTTRTYDVNPETGHVTEQVTVD
                     RKEATDTVIKVPAKSKVEEVLVPFATKYEADNDLSAGQEQEITLGKNGKTVTTITYDV
                     DGKSGQVTESTLSQKEDSQTRVVKKGTKPQVLVQEIPIETEYLDGPTLDKSQEVEEVG
                     EIGKLLLLQSIL"
BASE COUNT        10648 a         8149 c         6751 g        10165 t
ORIGIN      
        1 aaatatccaa ataaataaac tataaacaac aaaaatagaa ctatgttata tttcttattc
       61 aaaacattcc tccctatatt tttgattacc aatcttaatc atttacaact acattctaac
      121 aaactataaa agcgtttgtc gaattgaatt tatcaagcaa gcgaccaacc agctcatctt
      181 ttttctattt ctgccaatat gcgtgacagg taataatgat agccaaaaat agcaagagca
      241 agcaggagga taagagctcc tactcccaag ctgatggcaa ggatagtgga gagagactga
      301 accaagaata tgctcccaat tacaagggcc atcaggattg cactataaat aaacaataaa
      361 actatggcga ctatgccatt tgaacgattc accaggtccg taatgctact ccaattggtt
      421 gacagatttt taacgtcctt aaagtaatgg tggcaagaaa ggatgacact ggcaaggatc
      481 catgccacaa taaggtaaat catcgaaatg atgggcaagc ctagatatag agaaagacca
      541 agcaaagtca gaactggtaa aaaggactgg acagcatata taatccaaaa tttcactttc
      601 acataacgag caaagtcaaa gggtaaactc ttaagaaaat caacattttc cctctccaag
      661 gacaaggcaa ttgaatgcag gctggtgata ttgttattga caactgctat aaacactcct
      721 acaaaaaaca agggtaacca gtatggagga tgaatgtctg gaactatctg agaatctcgg
      781 attttggaaa tcagaccgat catcatgaga taaggaaaga aagcacttgt aaaaagcact
      841 gtaaccacgc cagtaccctg tcccaagagg gtgaggtggt agcgtaaaac catgcggaaa
      901 aatccctttt tagtggttga aattctctcc ttgctgcgac gttctttttt gaccttctcc
      961 tcactattaa gcaggatcac gtcataaaaa cgaggaagga ccttcttttt ggtcagataa
     1021 agcaggaaga gagttagtcc tatccaagcg agcagaccca atatggcttc tgtcgaaaaa
     1081 ggctccactg ctattttgta aaagatatga agaggataaa ggagaaatgg aatgtctcta
     1141 actttgtcaa caatacttcc aaaagtcgac tgaagaaaga agataaatat taaaggtatg
     1201 agaactccta tcccaatcat cacattcgaa aaaatagact gatactttct gaagaccgta
     1261 gtttgagcca agaaatgtac tgccactacc atcactaaag taacagagac aaataataag
     1321 gtcaaggaca gtagcatcaa aggcaaaccc aaccacagag aaggtgctag cctaatgtag
     1381 aggaccagaa aataagctag gattggtaca attccagcta gagctggcaa gaggacagac
     1441 agacctttgg ccattataat ctctgattct ttaaaggcat agggcctata ggaggccagg
     1501 tccttactct cataaaagac attgtaaaat gcagtgaaag aagttgaaaa ggccagcacc
     1561 agtaaaatag caaccatcga gctaaaataa ataggtattt cctcaaaagg aaaatgaatg
     1621 gctatattac taaaacagat gagcatcaag agactggaaa aaatgtaaga acttaggact
     1681 ctagcggaaa catttacttt tttcccagga ttcttagcct gcttctttcg tagattagcc
     1741 agattagctt cttgagatga atagaggata ttgatatcaa ctaatttttt aatgaccttg
     1801 agacgcatct gaaacctcct cttttctacc agcaaggcta aggtagatac tttccaaaga
     1861 ctggtctggg ttgtcttttc tcaagtcctc taccttacca caataaatca aatgcccctt
     1921 tttcaaaata gcaatccgat cacagacttg ctcagctacc tctagcacat gagttgaaaa
     1981 caaaactgtc ttaccttttt gcgcatgctc cttcatcatt tgcttcaaat caaaggcggc
     2041 ctggggatcc aaaccagtca agggttcgtc caaaacccaa atatcaggat cagacaagag
     2101 tgccccgatg acaaagactt tctgacgcat tccatgagaa agagtttcaa taacctgata
     2161 gcgattttca gcaaaatcaa aaacgttcaa tagcctagct agactagcct ccaagtcaga
     2221 tctactcaga tcataggatg aggcgatcaa ttcccaaaat tcattggccg ttaagcgtaa
     2281 aaataagtca ggcgagtctg ctacgtagcc aatctttcgt ttaatagcca agcgattttc
     2341 cgataactcc tgaccgtcta ccaaaatacg accactgctg ggtgaaatga tactgactag
     2401 ggattttata gtggtcgatt ttccagcccc attatgacca atcaagccca taatctctcc
     2461 attttcaatc tgcaaattga gattactcaa ggccttttta tcaccataca acttactaac
     2521 attttgaaat tcaatcatgg gacaactcct atctttatct gtattatata tcgctatact
     2581 agcactttga tacaaaaaaa tcaatacttt attttaagta gttaaaatag tttccttcta
     2641 tcttacgcaa acgtttgcgc taatagatac tttatgatag aataaagaac aagattgaca
     2701 agtaagagga aacattatgc aaaatcaaac actcatgcaa tactttgaat ggtatctgcc
     2761 ccacgacggt caacactgga cgcgtctggc tgaaaatgct ccacacctag ctcatctggg
     2821 gatcagtcac gtctggatgc caccagcctt caaggcaacc aacgaaaaag atgtcggcta
     2881 tggggtctat gacttatttg acttaggaga gttcaaccaa aaagggactg tccgcaccaa
     2941 gtatggtttc aaagaagact atcttcaagc cattcaagcc cttaaagcgc agggaattca
     3001 acctatggcc gatgtggttc tcaaccacaa ggctgctgct gatcacaggg aagcctttca
     3061 agttattgaa gtggatcctg tagaccgtac agttgaactt ggagaaccct tcaccatcaa
     3121 tggctggact agttttacct tcgatggtcg ccaagatacc tacaatgact tccactggca
     3181 ctggtaccac ttcacaggta cagactatga tgccaaacgc cgtaagtctg ggatttatct
     3241 gatccaaggg gacaacaagg gctgggctaa cgaggaattg gtcgataacg aaaacggaaa
     3301 ctacgactac ctcatgtatg ccgacctaga ctttaaacat cctgaagtca tccaaaacat
     3361 ctatgactgg gctgattggt tcatggaaac gactggtgta gctggtttcc gtttggatgc
     3421 cgttaagcat attgactctt tctttatgcg caacttcatc cgcgatatga aggaaaaata
     3481 cggtgacgat ttctatgttt ttggtgaatt ttggaaccca gacaaggaag ccaatctgga
     3541 ctatctcgaa aaaacggaag aacactttga ccttgtcgat gttcgtctcc atcagaatct
     3601 ctttgaagcc agtcaagctg gcgcaaacta tgaccttcgt ggcattttca cagatagcct
     3661 ggttgaactc aagcctgaca aggctgtgac ttttgtcgac aaccacgata cccaacgagg
     3721 acaagccctt gagtctaccg ttgaagaatg gttcaagcca gcagcctatg ccctcatttt
     3781 gttacgccaa gacggccttc catgtgtctt ttacggagac tactatggga tttcaggcca
     3841 gtatgctcaa gaagatttca aagaaatcct tgaccgcctc ctagccatcc gaaaagattt
     3901 ggcctatgga gaacaaaatg actactttga ccatgctaac tgtatcggtt gggtacgttc
     3961 aggtgctgaa aatcaatccc caatcgcagt ccttatctca aatgaccaag aaaacagcaa
     4021 gtcaatgttt gtcggtcaag aatggactaa tcaaaccttt gtagatttac ttggtaacca
     4081 ccaaggtcaa gttacaattg atgaggaagg ttatggacaa ttccctgtct cagctagatc
     4141 cgtaagtgtc tgggcagtca ataccatcta atagctcata ataaccaagc taggtccaag
     4201 cggatttggc ttttttgtat tcacaaaaag acctacccaa atggatagat ctttacttga
     4261 ttacaattta cctgctactg catccaacaa ttcttggatc ttaggttggt tgcttcctcc
     4321 tgccatggcc atgtctggtt taccaccacc acgtccatcg atgattggtg ctaattcttt
     4381 gacaaggttt cctgcatgaa ggtcttttgt cttgcttgct acaaggacat tgactttgtc
     4441 accgatagcg gcaactagga caagaagatc agagtagtct ttttgtttcc agttatctgc
     4501 aaaggtacga agggcacctg catcggatac agacacttga ctagcaatgt aacgatgacc
     4561 gttgacttcc ttaacatctt tgaagatatc gcctgcggct gcagctgcgg ctttttcttt
     4621 caactcagca ttttcttttt gaagttgacg aagttgttct tgaagtcctt ctaccttgtg
     4681 aggtacttcc ttgacttgag gtgctttcaa ggttgctgcg acagctttaa gagcatcctc
     4741 ttgttcacga taggcttcaa aggcttcctt accagtcact gccaagatac ggcgagttcc
     4801 tgaaccgatt ccttcttctt tgacaatttt gaagagacca atctcagaag tgttgccaac
     4861 atgagtacca ccacaaagtt caatagagta gtcaccaata gtcacgacac gaacttcctt
     4921 gccgtatttc tcaccaaaga gggccatcgc tcccatttct ttagcagtgt caatatccgt
     4981 ttcaactgtc ttaacttcaa gagcttccca gattttttcg ttgacttgct gttcaatcgc
     5041 acgcaattct tcagcagtta cagcttggaa gtgggtaaag tcaaagcgaa ggaattcaac
     5101 ttcgttaaga gatcctgcct gtgttgcgtg gtttccaagg atattgtgaa gggcagcgtg
     5161 aagcaaatga gtcgcagtgt ggtttttcat gacacggtga cggcgattgc tatcaattgc
     5221 caaggtatat tcttggttca aggcaagcgg tgcaaggact tcaactgtat gaagggcttg
     5281 accatttggg gctttctgaa cattggtcac agtagccaca accttacctg actcatccaa
     5341 gatttgtccg tggtcagcga cctgtccacc catttcagca tagaatggcg tttccgcaaa
     5401 gataagtgag gtagttcctt ctgatacagc ttctacttct gcattgtcag caacgatagc
     5461 caccaattta gaagacaatt ggctagcatt gtggttgaag acactttcta cagtgatgtt
     5521 ttgaagagtt tcattttgca tacccattga gccacccttg acagctgacg cacgcgcgcg
     5581 ttcttgttgt tctttcatgg ctgcttcaaa accttcacgg tctacagtca taccagcctc
     5641 ttcagcaatt tcttcagtca attcaactgg gaatccgtat gtatcataga gtttaaagac
     5701 atcttgacca gcaatgacag attgaccttt ttctttcaag tctgccacaa tgccttgggc
     5761 aaagtgttga cctgagtgaa gggtacgggc aaatgattct tcttcgctct taacgatttt
     5821 ctcaataaag tcacgtttct caagcacttc tgggtagtag ctttccatga tttttccaac
     5881 agttggaacg agtttgtaaa ggaaaggctc gttgataccc aatttttgac catgcataga
     5941 agcacgacgg agaagacgac gaagaacata accacgacct tcatttcctg gaagggcacc
     6001 atcaccgata gcaaatgaaa gagaacgaat gtggtctgcg ataaccttga agctcatgtt
     6061 gtcgccatct tggtcataaa ccttaccaga caatttctcg acttcacgga taatcggcat
     6121 gaagaggtcc gtttcaaagt tggtcttagc cccttggata acggccacca aacgctccaa
     6181 accagcgccc gtatcaatgt tcttatgtgg taattccttg tattcgctac gaggaacagc
     6241 agggtctgcg ttaaattgtg acaaaacgat gttccagatt tcgatgtaac ggtcgttttc
     6301 aatatcttct gcaagcaggc gaagaccgat attttctggg tcaaaggctt ccccacggtc
     6361 aaagaaaatc tctgtatctg gtccagaagg tcccgcacca atttcccaga agttgtcctc
     6421 aattggaatc aagtgacttg gatccactcc cacttcaatc cagcggttgt aagaatcttt
     6481 atcatctgga tagtaagtca tgtaaagttt ctcagctggg aagtcaaacc attcagggct
     6541 tgtcaaaagc tcataagccc aagtgatggc ttcatcacgg aagtaatccc cgatagagaa
     6601 gttccccaac atttcaaaca tggtatggtg acgcgcagtc ttccctacgt tttcgatgtc
     6661 gttggtacgg atagcctttt gggcattggt aatacgtgga ttttcaggga taatggtccc
     6721 gtcaaagtat ttcttgaggg ttgctacccc agagttgatc cacaaaagag ttgggtcatt
     6781 tacaggaacc aaacttactg atggttctac tgagtgacct ttggtcgccc agaaatcaag
     6841 ccacatttgg cgtacttgtg cactagatag ttgtttcata ttgtctcctt atttacttgt
     6901 ttaatgtgat tggctttcca gcatttccac atagtcaatc gcgacacaga gggaaatgac
     6961 taggtctgca taagcgtctt caagaaccgt tacggtatag gtagaggtca gatggaagag
     7021 ttccttctta atttccgcaa tcaactgatc gcgatcatcc agcaatttga aattcaaatc
     7081 ccagatattg ccctcgatac gaagacctag attatcaaac tcatacttat ctcgccagaa
     7141 ggtcaacttc ttacgaatga caaaactcga gccatcccga agctgaatct caaaacgagg
     7201 aagcaaggtc aagatttctt tactaatctc actgacttgt tcaccagccg catcatagat
     7261 ggtaaaggtt ttaggaatct taaaaaatga tccctccacc tgataggcaa tttctcccct
     7321 gtcatccttg atagcgaagc gttcgcctcc aagacgaaac ttttgtttga caagaaatgt
     7381 tttcatcaac acctccaaaa atcaaaagac aagctcatat cacgaagggc gaaaaaccgc
     7441 ggtaccacct tcattcaatg aacttgtcat tctcttgttc ttatgcaatt gtatgattga
     7501 gtagcatgac ttcctagctt agatggctcg cagcaccgcc atttctctgg actaagacaa
     7561 atgaaaatca attctcaact ttcttattat aacgtttttt taagcttgcg tcaactggaa
     7621 atgatctccg ttgaattaga ccaattccct acatctctga ttactttttc aggatatatt
     7681 ttttcttact gccgtttttc tttttatccc aaattttcat attactaaac acagctacta
     7741 gaatatttcc aaatataaag gtgcctatca cccaatatat ggactcagtt gttaggtatt
     7801 gtcgatccaa gccatccttt aaatgggata gtataacagt ttggttaaca atcataaagg
     7861 ttggccagaa actttttttg aaaaaagtag acattttcat tatttgttgc cgctttctgt
     7921 aaggttaata ctcaataaaa atcaaaaagc aaactaggaa gctagcctca agctgtactt
     7981 gagtacggca aggcaacgct gacgtggttt gaagaatata ggcttagtat actactaggc
     8041 aagcaaataa gcaactagaa tagaaaaaga tagggttcta aaaactgact tctattcctt
     8101 aaaaacgaac cagcttgact gattcgtctt cttacgttta tctcctactt ccgatacatt
     8161 ttaaactgta ggaagaggtc gctatatttc cctgtccatt tatggtcaaa tttctcataa
     8221 acttctaggt gtttcatggt ttcaacatct ggatagaagg ccttatcttc ctttgtttcc
     8281 tctgggagca attccttcgc tggtaggttt ggtgttgaat agccgacata ctccgcattt
     8341 tggagagcgt tttcaggttt caacataaag ttgataaagg cataggctga gtcttggttt
     8401 ttaactgttt tgggaatgac catattgtca aaccaaagat tgctggcctc tgtcggtacc
     8461 acataacgta gattttcatt tttttctaac atttggctgg cttcaccaga gaaggtcacg
     8521 ccgattgcaa cattattctg aatcatgtag cccttcatct cgtccgcaac gatagccttg
     8581 atatttggag tcagtttgta gagcttatcc actgtctctt ccaactgctg cggatccttg
     8641 gagttgaggc tgtagccgag ggaattgagt cctagtccca gcacctcacg cgccccatca
     8701 aaaagcatga tagaattctt atactccggc ttccaaaggt catcccaatg ctcaggcgct
     8761 tcatctacca tggtttcgtt gtagacaatt cctaaggttc cccagaagta agggatggag
     8821 aatttattac ctgggtcaaa ggactggttg agaaactctg gtccgatatt ttcgattcct
     8881 tcaatttttg aataatcaag cggaaccaag aggtcttcgt ccttcatctt gttaatcatg
     8941 tattcacttg gaatggcaat atcgtaggtc gttccaccct gctttatctt agtgtacatg
     9001 gcttcgttgg agtcaaaagt ctcgtactga acttgaattc ctgtttcttc tgtaaactga
     9061 gtcaagagtt caggatcgat atagtctccc cagttataga taaccaattt ttgactatct
     9121 cgactattga ttttactatc taaatgagtc gcaattcccc acaagacaag gataatcgct
     9181 gcaattcctg ctaaaaatga atagattttt ttcatgcttg ctcctccttc tcacgagaga
     9241 taaagtaata acctacaact aggataatac taaagagaaa gactagagca gacagggcat
     9301 tgatttctaa ggaaatcccc ttgcgagcac gagagtaaat ctcgactgat agggttgaaa
     9361 agccatttcc tgttacaaag aaggtcacgg caaagtcatc taacgaatag gtgaaggcca
     9421 tgaaataacc agtaatgata gacggagtca ggtaaggaag catgatttcc ttgaacatct
     9481 gaaattgact agctcccaag tcataggccg catgaatcat gtcgccattc atttccttga
     9541 gtcgaggcaa gaccatcaag accacgatag gaatggagaa ggccacgtga ctagatagaa
     9601 cggtcaaaaa gccaagtgaa aacttgagtt gggtaaagag aatcaagaag ctagcaccaa
     9661 tcataacgtc aggcgcaacc atgaggatat tattgagtga tagaaaggct tcttggtatt
     9721 tcttacgaga ctggtagatg taaatggcac caaaagtccc gataatggtc gctatcaagg
     9781 ctgataggaa ggccaagaaa aatgtctgag ccaaaatcag catgagtctc ccatctccaa
     9841 acatggtttc aaagtgagtc cagctaaaac ctgtaaagct attcatatca tcaccagcat
     9901 taaaggcata gccaatcaag taaaagatag gcaggtagag gaccagaaag accagtccca
     9961 gataaaggtt ggcaaatttt ttcatcgttc tctcctttcc ttagtcaccc acatggtgat
    10021 gaacatggtc aggatgagaa tcacaccgat agttgaaccc ataccatagt tgtcattggt
    10081 tagaaaattc tgctcaatag ccgtccccaa ggtgataacg cggttcccac caatcaaacg
    10141 ggtcagcatg aagagactca aacttgggat aaagaccgac tgaaccccac ttcgcacacc
    10201 gttcatagat agagggaaga tgacatgacg gaaggtctcc cacttagttg caccaaggtc
    10261 gtaactagca ttgatgagat tattatccat atcgtctaag acattgaaaa tcggcaaaat
    10321 cataaagggg agctcgatgt agcttgcgac aaagataaat gagaaatcag taaatagcaa
    10381 ctgctgtgaa ccaattccga taaattccaa gaattggtta atagagccat tctgaccaaa
    10441 aatcccgata aaggcataag ccttaagaag aaggttgatc caagttggca gaataatcag
    10501 cataatccag agttgacggt gtttgagacg ggtcaaaaag agggccgtcg gataactgat
    10561 aagcagtgtc acaaaggtca caatgcctgc ataaagcact gagttgaaac tcattttaag
    10621 ataggtcaag ttttgtgacg caaagtaaga tttgtaattt tctaaactga actggccttc
    10681 gatgttgaaa aaggattgac cgaaaatcaa gaccaagggt gccaatacaa agagggcaat
    10741 ccaaagcatg tagggtacta caaagagttt agagcttgtt ttcttcatct ctttcctcct
    10801 cgattgcatt gatcaaacct gcttcttgct cttcgatttc tacgtactcc tcaatacgag
    10861 catcgaactc ttcttcggtt tcattgagac gcatgatgtg gatgtcttct ggttcaaagt
    10921 ccagaccgat ttcctcaccc acgatggcct tacgggttga gtggatcatc cattcatttc
    10981 caagttcgtc ataggcgata atttcataat gcaccccacg gaagagctgg gtatcgacct
    11041 taacttgaag cttgccttct tcaggaaggg taatgcgcaa gtcctctgga cgaataacga
    11101 cctcaacagg ttcatttggc ttcatcccac catcaaccgc ttcaaagcgt ttgccgttaa
    11161 attcgaccaa gtagtcctca atcatggtac ctggcaagat gtttgactcc ccgataaagg
    11221 tggcaacaaa gtggttgatt ggctcatcgt agatgtccac aggggttcca gactggacaa
    11281 tctcgccatc attcataacg aaaatccagt cactcatggc aagagcttct tcctgatcgt
    11341 gagtgacaaa gacaaaggta atgcccaatc gttgttgcag ttcacgcagt tcgtactgca
    11401 tgtctgttct taatttcaag tccagcgctg acaagggctc atccaacaaa accacacggg
    11461 gttggttgat gatagcacgg gcgatagcca cacgctgacg ttgtcctcca gaaagtttgc
    11521 ggatggaacg tttttcataa ccttccaact gaaccatctt gagaacttcc gctacacgtt
    11581 gctcgatttc tttcttatca atgttacgca agcgaagtgg aaaggcaaca ttttcaaaca
    11641 cattcatatg tgggaacaag gcataggatt ggaagacagt atgtacgtcg cgcttgttgg
    11701 ttggaatatc attgatacga acaccgtcta gcatgatatc tcctgtcgtc gcatccagta
    11761 aacctgcaat aatgtttagg atagttgatt tccccgaacc agatgcacct agaagggtgt
    11821 agaatttccc ttcttccaac tcaaagttga tgtctttgag aaccttggtg ttgctgtctt
    11881 caaaaacttt agagacgttt ttgaattcga taattgattt tttcaattgg cataaattcc
    11941 ttctttttca tagattaacc gatcggggct ctgtcaggtc gccactacct cttgcaggga
    12001 gtaaaaccac ctgcatacat cttcgctacc aataggcttt cacccccctt tccatgacat
    12061 agcagcagct tttcaaatac agcttcctac ttgctttcac ccaagatccg gacttctctt
    12121 tcaagcgtaa tacctgagtg ttccttgact ttttcgataa ccgattggat caagtcctcg
    12181 tagtctttgg ccgttccatc tgcgacattg atcataaatc ctgcatgctt ttctgacact
    12241 tctacgccac cgatacgata gcctttcaag ccagcttctg aaattaactg acctgcaaaa
    12301 tgcccgactg gacgcttaaa gaccgagcca caagatgggt attccaaagg ttgcttgagt
    12361 tcacgtaggt gcgtcaagcg gtccatttcc tgcttgataa cctgatgggt tcctggggct
    12421 agggcaaatt taactgacaa gacaactgca ccagactcct gaatagctga atggcggtaa
    12481 ccaaaagcca agtctttagc agacagggtt tcgatttctc catccttggt caagacctta
    12541 caagactgca agatgtgagc aatctcgcca ccataggcac ccgcattcat aaagacagca
    12601 ccgccaacgc ttcctggaat accacaagca aactcaaagc cagtcaaact atgacggagg
    12661 gcaatgcgag ttgtttcaat caagttagcc ccagcttctg cttcaatggt atagccatca
    12721 acagaaacgt tattgagctt gtcacacaag atgacaaatc cacgaatccc accatcacga
    12781 acgatgatat tgcttgcatt gccaagaacc atccaaggga tattttcttg gttggcaaat
    12841 ttcacaacgc gagccaactc aaaacgattt cgtggaaaga ccaaataatc agcctctcca
    12901 cctacttttg tataactata gctatgcaag ggttccttaa aacggatatc aattccttct
    12961 aagatttcaa gcattttttc tcttacagac atgtcactct tccttttaca aaattcattc
    13021 cattatacca tttttagaga catttgacga ccataaaaat accttgtttg gattttgcat
    13081 aagaaaaaga ggttcccccc tttttatgat tttttacaaa agatttcctt ggttccatag
    13141 gcaaccagaa cgagctccag tgctagaatc acttcaacca agactggatt tgtcaaccag
    13201 cctacttgga aaagagatgg tgccagatca aagaaggcat gcaagccata ggctgctagg
    13261 agataaatcc atttcttctg gcgaacagct tggtaaaccc aaactgtcaa aagtaattgg
    13321 aaaccaagcg ccaagattcg ctcaaaacca agcaaataaa tctgccagac caaaagtgac
    13381 tgaatggttt ttaacatatt ttcagacagt aattgcataa cctgtggatt ctgagtttga
    13441 actgccgaaa gaacgatgta aagattgagt aaactaataa ggcctagaaa aatcaactcc
    13501 aagccaccat gccctaggcc ataggccaag gcatctgcct tttccaaact tctctttttc
    13561 tccaaccatt tgaagaaaac aagacgagcc gtttcctaaa aaaatgctgc catggctagg
    13621 ccatagataa tatagacaag cggtgatctt gcaagagggc aatactaccg tctttttgag
    13681 gatgcaaaat caagatatgc accagttttt ccaaaatctg cgaagagaca aagaaagcga
    13741 ctgcacccaa gcccaagaca gctagattaa tctggtattt ctttttggca aaccaaatgc
    13801 ttcctatcag aaaagctagc aacagcaaca tggtaataat gatatgaatg gtcattttct
    13861 tctcctattc tgccttttca atatcttttt tcatctcgtc aacattgaac ttagcaaaca
    13921 agtattgacg gtcttggact gggaaacgtt ggtccaactg gtcaactgct cccacctcga
    13981 taatgccttc cttgatgaca aaatccatga catgtccacc gaaggtcaaa tcatctgata
    14041 tgaagtgcag atggtagcct gccacactga ccccatggaa aatctcaggc gtccagaaac
    14101 caacaatagt ccccgcaaca ttgtcacgac tatattccgg ttgatgggtt gcgacatcag
    14161 caaacttggt atcgggtgtt gacttaggaa tcatacgcac atgcatatgt gaaaattccc
    14221 cccgaatctt gatagagcgg aaaagatttt ccccatcata ataagactca attcgttctt
    14281 tcaattcctt gtctgtcatc tcaaagcgct ggcggaaaat gacctctgcc tgatgcggta
    14341 ccactgcagc gtaaggaata agggcatctg gtgacacttc cacaatttct ggctggtctc
    14401 ctgacccttt ggcctgataa gccttgccat ccaagacaat caattcccca tcaatggaat
    14461 ccaaggttcc caaaccaagg tcaccatgtt ctagcaattc tcctactgtc atagtaccac
    14521 cataaaggcc agccatcaag gctccaagag tattgtattg aaataatttc actggttcct
    14581 gcacgttctt atccattcac tttcttgtct gttattctat aaatcttact cctaagtata
    14641 ccacatttgc ccctagatgt gaacgagaga aacgctctag acattgccaa gaaggaaaaa
    14701 aaagggtaca atgtaacaaa atcaagggag gtctggaatg aagaaacaaa gcaagtacaa
    14761 agaggtcgtt tcctatctga aaaatggtat cgagtctgaa cgatttccga cgggtagtcg
    14821 cctgccttct atccgtcaac tgagccttga ctttcactgc agcaaggaca ccattcaacg
    14881 agccctgctg gaattacggc acgaacaata cctctatgcc aagcctcaga gtggctacta
    14941 tgtattagaa caagggcaac atcaagacct agaaatcgag gttaccgacg aacatgccag
    15001 tgcctatgac gatttccgac tctgtgtcaa tgaaaccttg attggccgag aaaactacct
    15061 cttcaactac tatgacaatc aagaaggatt agaagaccta agacagtcca ttcacaaact
    15121 cctctttgag caagctctct actgcaaggc taaccaacta gtactgactt ctggaaccca
    15181 acaagccttg tttatcctct ctcaaatatc ctttcctaga caagccaagg aaatcttggt
    15241 ggaacagcca acctaccatc ggatgaatcg cctcttgatt gcacaggggc tggactatca
    15301 aacgattgaa cgaggcattg atgggattga cttggaggag ctggaaggcc acttcaaaac
    15361 aggaaaaatt aaatttttct acaccattcc ccgatttcac tatcctctgg gacattccta
    15421 ttctgagcaa gacaaacgat ctattcttaa cttagctgcc aagtatgatg tctatatcgt
    15481 agaggacgat tatctgggtg atttggactc caagaagggc caaaccttcc actatcttga
    15541 tacagaggag cgtgtcattt atatcaagtc cttctcgacc agcctttttc ctgcccttcg
    15601 tattacagca ctcattcttc caaatgctat caaagaagca tttgtggcct acaaaaatat
    15661 cctagactac gacagcaacc tcattatgca aaaggccctg tcactctata ttgacagtca
    15721 attgtttgaa aaaaatcgtt tggctcgctt gaccaatcat gaatcttacc aaaaacaaat
    15781 cgaggaaagg ataactaaaa caccttgtcc ccttcctcat tatcccctac acgatggttt
    15841 attgctagac ctgagacagt atcctaaaat cgccagtctc aaacacagtc aactgggctt
    15901 ggacttcttt gaagaggcct atttaagcac ctgtccttat caatttgcca aggtgtccct
    15961 agacaatctg gaaaatgttt taaactattt aaaagcagaa ttggaatgac atccaactct
    16021 gctttttctt attcttcaac ttcagttaaa cttgctgctt tttcaagata gctttggtaa
    16081 gttccttcat ccttaagttt ttggatgacc ttgtctacca cttctttcaa atcatcacta
    16141 ttttttctaa gagcaacggc attggcgtcg ccgtccttca tcttcaagct gacagttgcg
    16201 acagctaagc cagcgttttt agcagcataa ctaagtgcaa caggctcatc catatgaaca
    16261 gcatctactt ttccagcctg caattcattg actgcttcac ccatattagt tagggaagtt
    16321 aattgagctt ttggcaattg ttccttgacc attgattctg gaacagtccc tttttgggct
    16381 gcaatattag cactttctag gctagttaaa tccttgtatt tttccacatc agccttacga
    16441 accaagaaac taatcttgtt ttcatagtat gggattgaaa aatcaaagac ttcttttctc
    16501 tcgtcagtag cactaattcc tgcaactgct aggtcagcct taccagtttg aagactggtc
    16561 aaaacattat caaaactcat gcttgagatt tccaacttaa ccccaagttc atcagcgata
    16621 gcctgagcca tgtcgatgtc tgcaccgact acctggttct ttccatcaac caatgattga
    16681 aattcaaagg gtgcatagtc aggactggtt gccacaacta atttcccctt ttgcttaatg
    16741 gcctcaacag ctgactgaga accattagaa cctgactggc aagctactaa gaagaaactt
    16801 gcaagaaaat tacataaaac aaatatccat ttttttgatt tcataaataa acaacctctc
    16861 tgttaatttt gtataattat aacgatatcc aagttacttg tcaagtgttt tttaaatttt
    16921 tatctcaaaa atattttttc gttcaaaaaa aggagccatc agttgatttc aagctccttt
    16981 ttatacagaa ttaaactatt ttatagttcg acaatcttac ctgtttcaaa gtagacaacc
    17041 cattcacaga tatttttagc atagtcaccg atacgctcca agtaggaaat aacttggaaa
    17101 taatcacgac ccgtaacaat ggcttctgga tttttcttaa tctcttcagt cgcaaggtca
    17161 cggatagttt caaaatagtg gttaatttgc tcatccatgg aggccacccg gtatgcgtcg
    17221 tcaacagaac cattaagata aagatcaagt gctgcttcaa caacgctttt aacttcacgt
    17281 cccatttttt taatttcttc ctctacagct ggaatgcgct cttccccctt catacggatg
    17341 gttgcctgag caatggctac agcgtgatcc cccatacgct ccacatctga tacagcctta
    17401 aggacagtca agactgtacg caaatcttga gagactggtt gttggagtgc gatcatttca
    17461 aatgatttct tttccagttt cacttcgtat tcatttactt ctgcatcatc ttcgatgacc
    17521 tcttttgcca ggtcacggtc atgcgtgaca aaagcacgta ccgtacgatt gatttgtgag
    17581 agcacttctt gtcccatagc gtagaactgg ttatgtaatt tctctaaatc ttcttcaaat
    17641 tgagatcgta acatctttca tctccttatc caaattttcc tgtaatatag tcttccgttt
    17701 ccttgtgttg gggattaagg aacatctgct tggtatcatt aaattcaatc aaatctccat
    17761 ctaggaaaaa tcctgtctta tcagagatac gtgaagcttg ctgcatggaa cgggttacca
    17821 gaagcatggt gtacttgtct tttagaccat acaaggtttc ctcaatttta ccagctgaaa
    17881 tcggatccaa agccgaagtt ggctcatcca agaggatgat tttaggacta gttgccaaga
    17941 cacgggccac gcagacacgc tgctgttgac cacctgacaa tccaatagct gaatcatata
    18001 gacgatcctt gacctcatcc cagatagagg caccttgcaa ggctttttct acggcttcat
    18061 ccagaacctg cttatcctta attccattga tacgaagccc gtagacaaca ttctcataga
    18121 tagtcatagg gaaaggatta ggttgttgga aaaccattcc gatttcctta cgtaattcaa
    18181 ccgtatctgt acgcggactg tagatgttgt gaccattgta caccacggat ccagttgtgg
    18241 tcacctctgg attgagatct cccatgcggt tgagagactt gaggagggtt gacttccctg
    18301 atccagatgg accaatcaag gctgtaattt ccttaggttg gaaagatagg gaaacactat
    18361 tcaaagcctt ctttttatta taataaacgg acaagtctga tacctgtaaa atcgcatctg
    18421 tcatacggtt tcctttctaa ccaaagtgac cagatacata gtcattggtg gactgtagct
    18481 tggcattttg gaaaatagtt gcagtcttgt catactcaat caaatcaccc aagtaaaaga
    18541 agcctgtata gtcacttgca cgagcagcct gctgcatatt atgcgttaca atgatgatgg
    18601 taaagttttt cttgagctca aacatggtct cttctagttg catggtcgca atcggatcca
    18661 aggctgaggc tggctcatcc attaagagga tatctggctt aacagagatg gcacgagcga
    18721 tacagagacg ttgttgctga ccacctgata aggtcaaggc tgacttgtgg agatcgtctt
    18781 taacctgatc ccaaagggca gcctgacgaa gggaggtttc tacgatttca tctaggactt
    18841 gcttatcctt aactccagca cgttcatgcg caaaggtaat attacggtaa attgacttag
    18901 caaatggatt ggggcgttga aaaaccattc caatgtgttt acgcatttca taaacgttga
    18961 tttctggacg gttgacatca attccacgat agagaatctg cccagttact ttagcaatat
    19021 caatggtatc attcatgcga ttgagactgc gtaagtaggt agatttcccc gatcccgacg
    19081 gaccaatcaa agctgtaatt ttatttcttt caaattgcat atcaatcccc ttaatggatt
    19141 catttttacc atagtaaaca tggacatcct tagtagaaag ggctactttt tcttcaggaa
    19201 aggtaaggat atgcttctca tcccagttat atgttgacat ggcttctcct ttaggcagcg
    19261 gttaatttct tgtgtagata gcttccgaac ttacgagctc caaagttaaa aatcaggata
    19321 aagatcagga gcacagcggc agaacctgct gatacaatgg ttccatctgg aatagtgcct
    19381 tcactattga ctttccagat atggacagcc aaggtttctg cttgacggaa gatagagatg
    19441 gggctagtca cactgaggat attccagtta gaccagtcaa gagctggcgc cgattgccct
    19501 gctgtataga tcagagctgc agcttcgcca aagatacgac cagatgccaa gacgacaccc
    19561 gttacaatac ctggaagcgc ttctggaata acaacatgaa ccactgtctc ccagcgagaa
    19621 atcccaagag ccagaccagc ctcacgttgg gtatggtgaa cgtgtttcaa actatcctct
    19681 acattacgcg tcatctgagg caagttaaag actgtcaagg ccaaggcacc tgaaatgatt
    19741 gaaaatccat actcaaactg tactacaaag atcaagtaac caaagagacc caccaccact
    19801 gatggtaaag aggacaagat ttcaatacaa gtccgcacaa agttggtaac aggacctttt
    19861 ttagcatatt cagccaagta aatcccagct cccatagaaa gaggtacaga aataatcaag
    19921 gtaatgacca ataggaaaaa ggaattgtaa agctgaatgc caatcccacc acctgcttga
    19981 aaagcagaag accttccagt caagaaagac caagagatat ggggcaagcc ccgaaccaag
    20041 atatagagaa tcaaggaagc caagattgtc acaatgatgc tagcaatcgt atagaggaca
    20101 gctgttgcaa gtttatctaa tttcttagcg cgcataattt ttctttcctc tttctttcgt
    20161 aatcaattta atcacactgt taaaaactaa actcatcaag agcagtacca aggccagtga
    20221 ccagagaaca ttattattta cagttcccat gacagtgttc ccaattccca tagttaatat
    20281 agaagttaaa gttgcagctg gtgtggtcaa ggaagttggg ataacagctg agtttccgac
    20341 aaccatctgg atagctagag cctcaccaaa ggcacgcgcc atcccaaaga ccactgcagt
    20401 gaaaatacca gaacgggccg ccttcaagat cacacgccag atagtctgcc agcgagtggc
    20461 tcccatagcg aaactggctt cacgataata acgaggaacc gcacgcaagc tatccgttgt
    20521 cataaaggtt acggtcggca aaatcatgac aaagaggacg gaaatccctg acaaaatccc
    20581 aaaaccagtc ccaccaaaga cactgcgaac aaagggaacg acgacttgca agccaataaa
    20641 tccgtacact actgaaggaa tcccaaccag gagttcaata gctggttgca aaatcttcgc
    20701 cccttttggt gatacttcgg tcataaaaac tgctgcacca atagcaaagg gtgttgcgat
    20761 aagggctgag agaatggtaa cgataaagga acccaaaatc ataggaaggg caccaaattc
    20821 tttactagaa ggattccaag ttcctcccaa aagaaagtca aagatattca caccattgac
    20881 aaagaaggtc gacaagcctt tttgcgctac gaaaaccaaa atcatggcca caaggatgac
    20941 tatcaaagaa agacaggcaa aggtcaaacc ttttcctaat ttctccagac gagaattctt
    21001 tgatggaagc aacattttct tagctaattc ttcttgattc attattgtct cccttccaac
    21061 actgtcacag ttccggcagc atctttttca accttcattt ccttaatcgg aatatacttc
    21121 aatcctttga caatcccttc ttgggtctca tccgagagaa caaaattgag aaattctgca
    21181 gccaactcat tgggctgccc caatgtatac atatgctcat aagaccacaa gggccaatta
    21241 ttgctactta tattttctgg acttaagtca tagccattca acttcatgct tttgaccgaa
    21301 tcatctatat aggtaagaga taaataagag atagctcctg gactttttga tacgattgat
    21361 tttaccgctc catttgaatc ctgctcctga ctttgcatgg cagactgacc ttccataatg
    21421 acagtatcaa aggtagcacg agagccagag ccggctgccc gattgataac agagatgggt
    21481 aagtccttac caccaacctc tttccaattg gttacctcac ctatgaagat ttgacgaagt
    21541 tgctctgtcg ttaggttatc aacatcaacc tccttattga caatcagagc caagccagct
    21601 accgcgacct tgtggtcaac aagagcagaa gcatcaattc cgtctttttc ctcagcaaat
    21661 acatctgagt ttcctatatc aactgcccca gactgaacct gggacaagcc tgtaccagaa
    21721 cctccccctt ggacattgac cgtttttcca acatggatcg tgccaaattc atctgccgct
    21781 acttcaacca agggttgcaa ggcagttgag ccaacagccg ttatggattc tccacgatca
    21841 atccagctag cacagcctac taaacaagcc gtcagccaaa aagcgataag agacagagca
    21901 agcttttttc tttttttcac tgtttttctc ctcgaaaata attatgaata ctgtgaattt
    21961 tttaagtagt tctttatgag ttgacgcatg aattcttacc aaatttctgc gcaattgatt
    22021 atttatataa tataggctat attactcttt cctaacctcc ttttttcata tgtggataaa
    22081 atctcttgtc tatcccttcc cccattgtca cccattatag tcatttcgtg tctctttttc
    22141 ccctttttaa tgcaagggaa attactcttc ttagatgata atccaaaagc tagaaaggta
    22201 tctcaaacct ctctactctc ccagactagt ttacaactaa aaggaaaaga ttctatttta
    22261 tgagaaatct agtttacaag cggtaagaac gctaataact aaacttcttg tactctttga
    22321 aaatctcttc aaagcagtgt tttgagctat ctatggctag cttcctagtt tgctctttga
    22381 ttttcatcga gtagtaaaac tacatgtgat ggcaatcaag atatcaagaa tcatcctact
    22441 aaaaaaatcc atactttcac tataacatag aataagatat ttgactagca ttttcatttg
    22501 aatctgaggc cttttggaaa ataatttttc aaaacatttc cagtaacctt tgcaaagccc
    22561 aagccattgc ctttaaccaa aacttggtac caaccatttg gcagactttc tgccagctga
    22621 acggtttctc cagctgcata cttgacaaac gcttcttggc caatttcaac cgactgttcg
    22681 acctgactcg gtttcaaggc taaaccaaga gcgaaactgg gctcaaagcg tttcttctta
    22741 aaagtaccca gatgcagtcc attgcgagca atcttgagct tccctaaatc tggcaaaagt
    22801 tctggcaaga gataaagctg gtctccaaaa atctgcaaga tacccggtag attgaccttc
    22861 aaatggtttt gggcaaattc ctgccacaag gcaacttgtt cacggctgag gttactctta
    22921 cttgccttaa atttaggagc tggattgtta cccttaaact gtagatgggc aacaaactga
    22981 ccctctccct taaactgatg agggtacatc cgagccgttt ctggcaggtc aataccagct
    23041 accattccat tgatatgctc tactggcaac aagtcaaaat catactcttc cagcaaccaa
    23101 ttgacaatct cttcgttttc ctcgggtgcc caggtacagg tcgaataaac cagacgacca
    23161 ccttcagcta acatggtcac tgcatcctcc agaatttctc tttgcaagct agcacattga
    23221 ctcggataat ctaagctcca atagtccata gcatcaggtt gcttacgaaa cattccttca
    23281 ccagagcaag gggcatcaag aacgattaag tcaaaatagc ctttaaagac cttgaccaag
    23341 cggtcggcag attcattggt caccacgaca tttgtcgctc caaaacgctc catgttttca
    23401 accaaaatct tagcccgttt gcttgaaatt tcattggaaa caagtagccc ctcccctgct
    23461 agataggctg ccagttgagt tgatttgccc cccggtgcag cagccaagtc caagaccttc
    23521 ataccaggac tgggttgggc tacttgagcc accatttgag cagcaggttc ttgcgaataa
    23581 actaaacctg tagcatgctc aggcgatttc cctgaaacct tcccatagtg gccccaaggg
    23641 gtttgagtaa tggcatcaga aaaggaaagt tgctcttctt ttaagggatt gacccgaaag
    23701 gccgaaaccg cttcctcctc aaaagaggca agaaaatctc ttgcctcatc tcctagtatt
    23761 tctttatatt tttcaacaaa tccttctgga aatttcattt aagttctttt cctttcgtaa
    23821 atataggact gaatttcctc ctgcatctca agaggcacca tcatgaccgg ctgtctggtt
    23881 tgaaaatcag gagcttcacc aaaaagggtc acaacccgat agcccagact ttcccctaaa
    23941 atactagctg cggcataatc ccatggttgc agataggtga gataggtcaa caaatgccct
    24001 gacaaaatct tggcaaaact aatggccgca cttccataga cacgaacacc aagaaccgct
    24061 cggctcaaat cagccagccc ccattcattg gtttccagca taccactatt ccctgcaatg
    24121 agaaaatctc caagtggttt agttttaaaa ggagctaggg gcctatcatt tagacaaact
    24181 ggaaattccc caccaccgtg gtaacaatcc cctttgacca catcataaat cagaccaaac
    24241 tgtccctgac cattttcaaa ataagccatc ataacagcaa aatcttcctg ctgggctaca
    24301 aaattattgg taccatcaat gggatcaatg acccaaacct tgccctcttg aaccgaggct
    24361 cgcagacaac cttcttcagc acaaatctta tcctcaggat aacgagacaa aatctcacca
    24421 accaagagtt cctgaacttc tttgtccagt ctggtcacca aatctgttgg agaggacttg
    24481 gtttcaacac gcaagtcttc ctgcatatgg tcaagaatgt actggcctgc tttcttaaca
    24541 agccctttag caaattcaaa tttactttcc aagagaaatc tttccttccc ctttttcttt
    24601 ggcagcctga actgctcggt aaagtgaata gccactaacc gtttcaaatt ctcgtcccaa
    24661 acgtttctct tcgctcttgc ttggcacgac cgctttgaat cccttatagg agtccagtaa
    24721 ctttttagcc tctactttgc cttcataggc agcttcaaca tcattaaaaa aagaaagcac
    24781 tgaagcaagt tcttcagtgc tccacgacaa atctagtggg taactatact gtttgttcat
    24841 taactaatac cagctctcat tcttgcttct tttagttctt gcttacgata actacgaggg
    24901 agaaaagcac gaatctcatc ttcattaaaa ccgatttgca tacgcttggc atcaataata
    24961 attggacgac gcaaaagact aggatactgc tcaatcaaat gaagcaattc cgataccgaa
    25021 atactctcta catcaatatt caatttttga aaaatttttg aacgagttga aatgatgtca
    25081 tcagtaccat tttcggtcaa ggaaaggatg tgttgcaatt cttttcttgt taaaggactg
    25141 gtcataatat tgtgttccac aaagggaacc ttatgttttt ctaaccaggc cttagcctta
    25201 cgacatgatg tacagctcgg tgatagaaat agtgtaatca tgcttttctc ttcttatcta
    25261 tactttgcta cttctattat acaaaaaaat aaggcgcttg actagggatt tttagaaaaa
    25321 aagcctattt tttcaagaaa aataggcttt ttgcgaacga ttgacacaat tggatttggt
    25381 taattcactc ttaacgatgg ttttaaacga tatatatttt tatatatgta aattaaaaac
    25441 atctttcctt tcacttccta cgacttttca gatacagata gccaaagaag ttttcataga
    25501 gggcaaaaaa gaggaggaag gcgtgaagaa agaaggtctc tggcaaaatc ataataacag
    25561 gatccttggc tggatcaaaa agccaggtat catctcccac aaagagaatt tgatggaaaa
    25621 gagtaaagaa ttggtcaaaa ccaatcaaaa ctcccccaag tccaatcatc acaggtaaga
    25681 ctactagagc caggagactt tttcgataaa gagacaaaaa gtcctttttc acaatcctat
    25741 tgacaaagac atagaaactt ggcagtgtca ctagagctac tagctgaacc aaatgaaaga
    25801 gattcttgac cactgcgaaa tggtgcagac cagctgctga cgaacgaaaa tcaggcatct
    25861 gtaagacctg actaaaagga ttggtcagat aattcatcaa gatatgaaaa ttgtattgaa
    25921 cggtttctgg ttttagatag actcgattcg ttaagtttag ccactgaatc tccataggat
    25981 agaaaatcca agccagataa atggtcagaa ggattgagag ggagaggaga aagagcatag
    26041 agccccaaaa ggtcaattta gttttcatca aaatcccact ccgcaaggct agaaaccaca
    26101 tgtgtcggtg cgattggcag gccagctact tcttctgcct tagtaaaacc tgtcgtcacc
    26161 aagagcgttg gaatgccatt gtcaatccca gcccggatat cagtcaaata attgtcccca
    26221 accatgatta actcttcacg ttccaaacct aagtgctcaa ccgccttgtc cataatgatg
    26281 gcatttggtt ttccgatata aaccggcttc actcgtgtcg ctacttcaag cagcgtaatc
    26341 agtgagccag cacctggcaa aagaccacgt tccgtcggga tgttgaggtc aggattggtt
    26401 ccgataaaat gggcaccctt ttgaatagca agagttgctg tggcaaattt ttcatagtcg
    26461 acttgccaat ccagaccaac taccacgtag gcagggtttt ccttgtcttc cacataacca
    26521 gccgccttga tggcttcctt gagtcctgct tctccgacga catagacagt cttttcaagc
    26581 cccaaatcat tcatatagtc gatggttgcc aaagtcgctg tgtagacagt cgatagaggc
    26641 gtatcgatat taaaattctg agccaacatc tccttaacac tctctggagt gcgggttgta
    26701 ttgttggtta caaagagata gggaatgtcc cgcttttgca attcatgaac aaaagtctct
    26761 ccagcaggga ttcggtcttt ccccttataa atggttccgt ctaaatcaat taaatagcct
    26821 ttatatttca tctatttctc cctaaacctt ttttatttct tgccaagtaa tgattgcttg
    26881 ggcattgata accccatcac ttgtaatttc atgcttgctt tccagtccag tccgttcaac
    26941 agccgatgta atcaccccac ctggtcgaac ttccttgaca tacttgaggt tgattttctt
    27001 gggaatatag tgggtcaaaa aatccgctcc catgacctca aaaatccagt ccaagtattt
    27061 actgttattg acatgaccat tcatatccaa gtcgtaaaaa cgaacatggt aatccttgct
    27121 gatcggctct tccaaggatt catacttcgg tccacggata agttttttat caaaatcaga
    27181 ctggtaagga gccacaatct caggttcaac agcatggact tttcgactgt cgcggtccat
    27241 gagaacaaag gtcgccatca tatggatgag ctcctgcccc gcttcattat aaatagtaaa
    27301 gcgacggtag caaaaaagtc gattgtagct caaggcttcc gtttcgatgg taatttcttc
    27361 cgcaaaacga ggcaaacgaa ccacctcaat atcatattct gcgataatcc agaccagatt
    27421 atagtcttcc aaaatggcct tatcactaac tcccagttca atcgattgca tccctgaaac
    27481 ttgcagtgac agcaaaatca catctggaag tttgatatga ccgttcatat cagccatatc
    27541 aaaaggaatt ttcattttca tttgataagt taagcccatg atcctactcc aaaataaatc
    27601 gttctgctac agtatctccc aaaaagagac ctctctttgt catgcgaacg tggtcaccct
    27661 caatctgcat gaggccttgt tgaaccaaat ctctgacaat ttctccataa agttcagcaa
    27721 aagactgtcc aaatttttcc tcaaatcgcg ccatggaaac cccggatttc ttgcggagtc
    27781 ccaagaacat ttcttcttcc atttgctcct tttgactcag gtgatcttct gtaatacaag
    27841 cattgccttc ctcaaccgca ctgagataat gacgaatggg accatgattt ttatagcgta
    27901 ctccattgac ataaccagat gcccctgcac caataccata gtattcagca ttgtcccagt
    27961 acatgagatt atgacgactt tcaaagccgg gtttggagaa attagaaatc tcataatgct
    28021 caaaacccgc tcgctccagc tctgcaatga tgtactcaaa catctccgct tctagttcct
    28081 ccttaggcag aggcaatttc ccacgtcgca tccggttcat aaagaccgta tggttttcta
    28141 aaatcaaact atacaaactc atgtggggaa tatccaatcc aatggcttta gccacatttt
    28201 cctttacttg ctccatggtc tgaccaggca gagcataaat caaatcaatg gagatgttgt
    28261 caaaaccagc cagtttcagg cgatcgatat tttcataaat atccttctcc aaatgactgc
    28321 gcccaatctt tttcaacatc ttatcatcaa aggtctggac acctagcgaa acacgattga
    28381 cagccgaatt tttcaaaaca gctatcttat ccgcatccaa atcgcctgga ttggcttcaa
    28441 tggtcaactc ttccaagaca gacaaatcca agtttttagt caagccattc agtaacacct
    28501 ccagttgcgg agccgacagg gctgtcggtg ttccaccacc gatataaagg gttgacaact
    28561 tttcaatatc ataagaacga aactcttcca gcagatgctc taaatagctg tcgactggct
    28621 gatttttgat gaagaccttt gaaaaatcac aataataaca aatctgggta caaaatggga
    28681 tgtgcacata ggctgacgtt ggttttttct gcatagtaat tattatacca caaagactag
    28741 attccagata aaaatcacca tccccagata catagtccgt ccggagatgg tgatggttta
    28801 ttcttctgtt atatcaatca caatctcttc tgagtcatca agagcttcgg ctttttcttg
    28861 ccattgttcc ttgagattat ttaattgatt ttttgatgct tctgtcgctt gaaaagcata
    28921 ggatttagct tgagcaagta tactgtccac agtgatttca cctgactcaa cctgttcttt
    28981 tgttttcaga acaaaatctg tagcctgctc cttaacttct gtcagttttt cacagacttg
    29041 ctccttggca tactccggat cttctctcaa atcatctaga aaatcttgag cctgactgca
    29101 aacttgtttg cccttatcac ttgttaaaaa caaggcaaga gctgcacctg aaacggttcc
    29161 taaaaggatt gaggataatt tacccataag gattctcctt ttttattttt tgaaaaattt
    29221 acttgcaaga cgaagagctg acagacttgc accagtcttg agtgtttttg aaccagctga
    29281 tgaagctttc ttgctcaaga cacgcgcatg gtcattgagg tctgaaacag atagagataa
    29341 atctgcaaca gcactgaaga gtggatcaat cgtagccacc ttgacattga tatcatctgc
    29401 caagacattg accttagcca acaactcatt ggtgtgatgc aaggtcacat ccacatctga
    29461 agtcaaggtt ttaatcgtct tttctgtttc atcgatgaca cgaccaagct tttgtacagt
    29521 aatgatcaga tagaccaaaa agacaatcac agctagggca acaagaatat atgcaacttc
    29581 taacatttag ttttcctcct ctgtaatata gtaaggggcc ttctttcgat tttgataaat
    29641 aacgatcatt ataccgagac cgataaagac aactgacagc cattgggaca ctcgaaggcc
    29701 gaagaacatg agactatctg ttcgcatacc ttcgatgacc atacgaccga aaccatacca
    29761 aatcaagtaa aaggccgtga tatgacctcg tctgagactc ttccatttcc gtctaaaaat
    29821 cagaatcaag gcaaagccaa gcagattcca tagagactca taaaggaaag tcggttgacg
    29881 gtagctcccc tcaatataca tctggtcacg gataaagcca ggtagataat ccagattatc
    29941 cactgttgca ccataagctt cttggttaaa gaaattaccc caacgcccca aactttgagc
    30001 aatcataacg ctaggcgccg caatatctag aaaatcccaa gtattgatga gtttacggtc
    30061 agcaaagata tagagcacaa gagccccagt tatcaaacca ccgtaaatgg ccaaaccacc
    30121 attccaaatg gcaaaaatct ctcctaaatt ctgactatag taatcaaatc ggaaaataac
    30181 atagtagaga cgagctccta aaatagccaa gggaaaggct actaagataa aatctaaaat
    30241 atcgtctggt atgatcttct ttctaggtgc ttctttcatg gtcaaataaa ccgcaagaat
    30301 caagcctgtc acaatacata aggcatacca acgaatggct aggggtccta gttgaatagc
    30361 aattggatca agcattttgc acctcatttc gagctatgag acttgtcagt cgttcgtcga
    30421 acaaacgggt agcatcaaag cccatttcct tggcacgata attcatggca gctgcctcaa
    30481 tcacaacaga gatattacga cctgttttaa ctggaatacg aatacgagga atggctacgc
    30541 cagaaacttc aagttcctct gcattgtttc caagacgatc aaaggtctta tgcgtatcgt
    30601 aattttccaa atagacagca agctgaacct gtgaagaatc cttgacagca ctcgcaccgt
    30661 agagactcat aacatcgata ataccaaccc cacgaatttc aatcaagtgt ttcaaaattt
    30721 cagctggttc accccagaga gtaatctcat ccttggcaaa gatatcgaca cggtcatcgg
    30781 ctaccaaacg gtgaccacgt ttgacaagct caagacctgt ctcgctctta ccaattccac
    30841 tatctccctg aatcaagacg cccatcccat aaatatccat caagacaccg tgcacactgg
    30901 tacgttctgc caaacgagaa tccagatagc tagataactc tccagataaa cgactggtag
    30961 ctgcacggct ggttaaaata gcaatcttac attctctagc agcctttaac atctcctctg
    31021 gaaccaccaa accacgggca acaatgactg ctggtgtctc aggtagaaac atttttttca
    31081 aaacttcata acggctgttg gaaggcatgc tgatcagata agaccactcc ttcatcccca
    31141 aaagttgaat ccgctctggt gtatagtagt caaaatagcc tgtcatttca agaccaggtc
    31201 gcgtaatatc cgctgtattg atttcctttt caagcaattc tggttcacca tagacaatat
    31261 ctagtctaag cttttcaatc acttctttta ctaaaaccga catcatttcc tccttcaaat
    31321 gaattcttct ctctattata tcaaattgta ggaggaagtt tcagattttt gcaggctttg
    31381 gagtatttat ttaaaagaaa aaggactaga tttctctagc ctttcatttc aattagaatt
    31441 ttttacgttt acgagctact tctgatttac gtttacgttt tacagaaggt ttttcataga
    31501 attcacgttt gcgtgtttct tgaagagtac cagctttagt aaccgcacgt ttgaaacggc
    31561 gaagtgcgtc gtcaagagat tcattcttac gtactactgt tttagacatt tttttcactc
    31621 ccttcaagtt caatatctat ttcattctac acgtaaaagg aataattgtc aagcaaaaat
    31681 gcggtttaat tttgattttt tcttccattt atacaagagt tgaaagcgtt caatagaaca
    31741 ttgctttttt atttttcgag taagctaagc gcttcagcat ctgcgatgat ggttacatca
    31801 gggtgatttt ggaggctact cgcaggtagg ttctcagtca ctgggccaga tactgttccg
    31861 gcaatggctt ctgctttcga ctcaccataa gcaaaaagaa taatagactt ggcatccaaa
    31921 atgtttttaa tccccattga aatagcttgg gttgggacgt cttcaatctt ggcaaagaag
    31981 cgagcattgg cttcgatagt agactggtca agttctacta gatgcgtttg actgtcaaat
    32041 ggagtaccag gctcattaaa gccgatatgc ccattgcgac cgattcccaa gatttggagg
    32101 tcaactggat ggtcagccaa aatttggttg tagcgttcaa cttcagcttc agcattgtcc
    32161 ttaacaccac gaggcaagaa actttcttta aatggttttt ggttgaacaa gttttcttgc
    32221 atgaagtaac gataagactg tggattgtcc ccatcaaggc ccacatactc atcaaggttg
    32281 acactggtta gatttgaaaa atcaaggtca ctctcaacaa tttccttgta aaattcaagt
    32341 gggctacttc ctgtcgcaag tcctagagtt tgagctccat tagccaattt ttccttcaaa
    32401 atctcaaaag caacttttcc accttgaact tggttttcaa ctttaataac tttcatcttt
    32461 tcatcctcca tttctgtcta tatttattat atggtataga ccaatttttg tcaagtgaaa
    32521 acgatttaat ttctaaaaaa agagcgtcca aacttgaaac gtgttataat ggataggatt
    32581 agaacttaga aagaatgaac agatatatga atacagctga ttttgatttc cacttgccag
    32641 aggaattgat tgcccaaacg ccccttgaaa aacgtgatgc ctccaaactc ctcatcgtca
    32701 accgtgagac aggagaaatg caagataaac atttccactc tattattgat atgctggaac
    32761 ctggtgatgc ccttgtcatg aacgacaccc gagttctccc tgcccgcctc tatggtcaaa
    32821 aagtggagac aggaggtcat gtggaacttc tcctccttaa gaacactagt ggagacgagt
    32881 gggaagttct ggctaaacct gccaaacgcc tcaaggtcgg tactcgtatc agctttggtg
    32941 atggccgcct cagcgctgtc gttacagaag aattgaccca cgggggacgc attgtccgct
    33001 ttgaatacca aggaattttc ctagaagtct tggaaagtct gggagaaatg cctctgccac
    33061 cttatatcca cgaaaaatta gatgaccgtg aacgttatca aaccgtctac gccaaggaaa
    33121 gcggctctgc tgcagcaccg actgctggtc ttcacttcac caaagaactg ctggcagaaa
    33181 tccaagctaa gggtgttcat ctagtctatc tgactctcca tgtcggactc ggaaccttta
    33241 gacctgtttc tgtggataat ctggacgaac acgaaatgca ctcagagttc tatcaacttt
    33301 ctgaggaagc tgctgccacc cttcgctctg tcaaagaaaa tggtggtcgc gtcatcgctg
    33361 tcggaaccac ttctatccgc accttggaaa ctattggttc caagtttgat gggcaaatcc
    33421 aagcagattc tggttggacc aatatcttta tcaaacctgg gtatgagtgg aaggtcgtgg
    33481 atgccttctc aaccaacttc catctgccaa aatcaactct ggtcatgttg gtttctgcct
    33541 ttgcaggccg tgaattagtc ttagatgcct accaccatgc catccaagaa cactaccgct
    33601 tcttcagttt tggtgacgcc atgtttattt attgagaaag aatttctcta attcttctaa
    33661 taccaataaa tcgctaagat attatttcaa agaacatcta caattgaaac tctagctagc
    33721 tgtagaagac gcctagtaca ttgaaattaa aatgcttccc cctagcttcg aaaatattgc
    33781 catagattgc gttgactctc caaattgatt catctatatt ttatttcagc ttcctatatt
    33841 ttcttcgctg tttgtaaatc aaaatgcaag acacatgagt agcaccatat ttgttactct
    33901 tatctgtcct ctcaagagac tattatgagt tatttcagaa tcattcacta ctttgaccct
    33961 gactctcctt agtctcaaaa tcaaagactt atactcttca aaaatctctt caaaccgcgt
    34021 caacgtcacc ttggattata tatgtgactg acttcgtcag ttctatctac aacctcaaag
    34081 cagtactttg agcaacctgc gactagtttt ctagtttgct ctttgatttt cattgagtat
    34141 taaacaaaaa gtgaacaaat ctgaattcta atgtacagaa gactaggctt gttcactttt
    34201 ttatagtcgc tataagatga ccttatctat agctttttat atataattat atattcagac
    34261 atactattat caattttgtc gcagggagga atctgttaac gcacccattc accattatca
    34321 ttgactctat agccatctat acttgtattg accgctaact cacccgatgt atttacataa
    34381 taccatttac caccaacttg gaaccattga ttgactttca tagaaccgtt gctgttgagg
    34441 tagtaccatg aaccattaac ttgtacccaa cctgttgcca tggaaccatc agtattataa
    34501 aaataccaca taccattttc ttgtttccag cctgttgttg gagcaactgc tttagctggt
    34561 tctactgcta catctgttcc ttggttagat gtaacagata caggatacga aggaatagat
    34621 gattgctcag gaacaacaac tttttcaggt tctctcgtcc ctctccttat acgtcttttt
    34681 accatctctt tagtaatttg acgagaagta gtttcttcaa ttgttccatc acgttcatct
    34741 acagtataga ttgtagtaag agtaatttac caatttctcc tacttcttct acttcttgac
    34801 ttttatcaag agttgggcca tcgagatatt ctgtttcaat tggaatttct tggacaagaa
    34861 cttggggctt ggttcctttt ttaacaactc ttgtttgaga gtcttctttt tgacttaaag
    34921 tactctcagt tacttgtcca ctctttccat ctacatcata agttatcgtt gtaactgttt
    34981 tcccattctt tcctagagta atctcttgct cctgtcctgc agaaaggtca ttgtctgctt
    35041 catatttagt agcaaatgga acaagaactt cttcaacctt gcttttagct ggaactttga
    35101 taactgtatc cgtggcttct tttctatcaa cagtaacctg ttcggtaaca tgaccagtct
    35161 ctggattaac atcgtaggtc cttgtcgtag ttacatagcc atcctctcca tcaattgtaa
    35221 caggattttc actacggtct tttgtttcat ctttttcata acgaattcgc gtacttgaaa
    35281 ttttcttggt tactacctta ggtttagtcg ctacttttac aataatatcc ccattgtcag
    35341 cgtcatcata ctctattccc tcttctttat ctctagtatc atctctgaca tattgaatcc
    35401 catcagcagc atgaacaaaa cttgtattca gattcctcct aaaaataaag ttagcccgat
    35461 taccgcagaa ccaaaaatct ttccgagttt acgtattgca tagcgcttat tagtattaga
    35521 ttttgccatt acatcctact tctagtatag catcttttct atcaaacgtt aaacaatata
    35581 ctttatatat aaaatagact tagaatgata tattgattat tgaactaaca ctttaactat
    35641 atcgtaatca atctcatata taaaggattg cagacatctt atctaaatac atgctaatat
    35701 atttagatac aaa
//
LOCUS       DAVLXH010000018        32525 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00028199
            SAMN33607166-rid17955573.denovo.018, whole genome shotgun sequence.
ACCESSION   DAVLXH010000018 DAVLXH010000000
VERSION     DAVLXH010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607166
            Sequence Read Archive: SRR23725544
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 32525)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32525)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721421.1
            Genome Coverage       :: 115x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:42:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,210
            CDSs (total)                      :: 2,161
            Genes (coding)                    :: 2,023
            CDSs (with protein)               :: 2,023
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 73 of 138
            Pseudo Genes (incomplete)         :: 60 of 138
            Pseudo Genes (internal stop)      :: 40 of 138
            Pseudo Genes (multiple problems)  :: 31 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32525
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607166-rid17955573.denovo.018"
                     /strain="AUSMDU00028199"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1349"
     gene            <1..645
                     /locus_tag="VYO11_000964"
     CDS             <1..645
                     /locus_tag="VYO11_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HEV1595552.1"
                     /translation="KNGVPLSDVWNIPFLNPKAKERVGYPTQKPILLLEQIIKIATDK
                     NDIVLDPFCGSGTTLVASKILNRNYMGIDLSEEAINITQQRLENVIKTSSNLLNKGIE
                     AYRTKTEEEENILKLLQAKIVQRNKGIDGFLPKHFQKKPIPIKIQKNNECLNESISLL
                     QNAINSKKLDFGVVIKTHSDNLLFDFDTIPENIIVVDHFELTIEKWLSKSQQLL"
     gene            complement(721..2283)
                     /gene="guaA"
                     /locus_tag="VYO11_000965"
     CDS             complement(721..2283)
                     /gene="guaA"
                     /locus_tag="VYO11_000965"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HEV1595553.1"
                     /translation="MSNISTDLQDVEKIIVLDYGSQYNQLISRRIREIGVFSELKSHK
                     ISAAEVREVNPVGIILSGGPNSVYEDGSFDIDPEIFELGIPILGICYGMQLLTHKLGG
                     KVVPAGDAGNREYGQSTLTHTPSALFESTPDEQTVLMSHGDAVTEIPADFVRTGTSAD
                     CPYAAIENPDKHIYGIQFHPEVRHSVYGNDILRNFALNICKAKGDWSMDNFIDMQIKK
                     IRETVGDKRVLLGLSGGVDSSVVGVLLQKAIGDQLICIFVDHGLLRKGEADQVMDMLG
                     GKFGLNIVKADAAKRFLDKLAGVSDPEQKRKIIGNEFVYVFDDEASKLKDVKFLAQGT
                     LYTDVIESGTDTAQTIKSHHNVGGLPEDMQFELIEPLNTLYKDEVRALGTELGMPDHI
                     VWRQPFPGPGLAIRVMGEITEEKLETVRESDAILREEIAKAGLDRDIWQYFTVNTGVR
                     SVGVMGDGRTYDYTIAIRAITSIDGMTADFAKIPWEVLQKISVRIVNEVDHVNRIVYD
                     ITSKPPATVEWE"
     gene            2425..3123
                     /locus_tag="VYO11_000966"
     CDS             2425..3123
                     /locus_tag="VYO11_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000936186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEV1595554.1"
                     /translation="MLPAYMKIHDQIKKDIDEHRWAIGERLPSERDLAEQFAVSRMTL
                     RQAVSLLVEEGVLERRVGSGTFVSSTRVQEKMRGTTSFTEIVKSQGKVPSSQLISYKK
                     TIPNEQEVAKLGIFPTDNIIRMERVRYADQVPLVYEVASIPEKFIKDFKKEEITSHFF
                     QTLQKHGYRIGKSQQTIYARLAKEKIAHYLEVEKGHAILGLTQVSYLEDGTAFEYVKS
                     QYVGERFEFYLENN"
     gene            complement(3166..4062)
                     /locus_tag="VYO11_000967"
     CDS             complement(3166..4062)
                     /locus_tag="VYO11_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HEV1595555.1"
                     /translation="MSNSLKGTLLTVVAGIAWGLSGTSGQYLMAHGISALVLTNLRLL
                     IAGGILMLLSYATAKDKILVFLKDRKSLLSLLIFALIGLFLNQFAYLSAIQETNAGTA
                     TVLQYVCPVGILIYSCIKDRVAPTLGEIVSIIFAIGGTFLIATHGQLDQLSMTPAGLF
                     WGLFSALTYALYIILPIALIKKWGSSLVIGVGMVIAGLVALPFTGVLQANIPTSLDFL
                     LAFAGIILIGTVFAYTAFLKGASLIGPVKSSLLASIEPISAVFFAFLIMNEQFYPIDF
                     LGMAMILFAVTLISLKDLFLEK"
     gene            complement(4071..5006)
                     /locus_tag="VYO11_000968"
     CDS             complement(4071..5006)
                     /locus_tag="VYO11_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HEV1595556.1"
                     /translation="MKWTKIIKKIEEQIEAGIYPGASFAYFKDNQWTEFYSGQSDPEH
                     GLQTEAGLVYDLASVSKVVGVGTVCTFLWEIGQLDIDRLVIDFLPESDYPDITIRQLL
                     THATDLDPFIPNRDLLTAPELKEAMFHLNRRSQPAFLYSDVHFLLLGFILERIFNQDL
                     DVILKDQVWKPWGMTETKFGPVELAVPTVRGVEAGIVHDPKARLLGRHAGSAGLFSTI
                     KDLQTFLEHYLADDFARDLNQNFSPLDDKERSLAWNLEGDWLDHTGYTGTFIMWNRQK
                     QEATIFLSNRTYEKDERAQWILDRNQVMNLIRKEE"
     gene            complement(5003..5728)
                     /locus_tag="VYO11_000969"
     CDS             complement(5003..5728)
                     /locus_tag="VYO11_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001102210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CppA family protein"
                     /protein_id="HEV1595557.1"
                     /translation="MNVNQIVRIIPTLKANNRKLNETFYIETLGMKALLEESAFLSLG
                     DQTGLEKLVLEEAPSMRTRKVEGRKKLARLIVKVENPLEIEGILSKTDSIHRLYKGQN
                     GYAFEIFSPEDDLILIHAEDDRASLVEVGEKPEFQTDLASISLSKFEISMELHLPTDI
                     ESFLESSEIGASLDFIPAQGQDLTVDNTVTWDLSMLKFLVNELDIASLRQKFESTEYF
                     IPKSEKFFLGKDRNNVELWFEEV"
     gene            complement(5812..6447)
                     /locus_tag="VYO11_000970"
     CDS             complement(5812..6447)
                     /locus_tag="VYO11_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-alkyl-2-acetylglycerophosphocholine esterase"
                     /protein_id="HEV1595558.1"
                     /translation="MAVQLLENWLLKEQEKIQTKYRHLNHISVVEPNILFIGDSIVEY
                     YPLQELFGTSKMIVNRGIRGYQTGLLLENLDAHLYGGAVDKIFLLIGTNDIGKDVPVN
                     EALNNLEAIIQSVARDYPLTEIKLLSILPVNEGEEYQQAVYIRSNEKIQNWNQAYQDL
                     ASAYMQVEFVPVFDCLTDQAGQLKKEYTTDGLHLSIAGYQALSKALKDYLY"
     gene            complement(6449..7276)
                     /locus_tag="VYO11_000971"
     CDS             complement(6449..7276)
                     /locus_tag="VYO11_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV1595559.1"
                     /translation="MMIKIIATDMDGTLLDARGQLDLPRLEKILDQLDQRGIRFVIAT
                     GNEIHRMRQLLSPLVDRVVLVVANGARIFENNELIQAQTWDDAIVNKALAHFKGRACQ
                     DQFVVTGMKGDFVKEGTIFTDLESFMTPEMIEKFYQRMQFVDELTSDLFGGVLKMSMV
                     VGEERLSSVLEEINALFDGRVRAVSSGYGCIDILQAGIHKAWGLEELLKRWDLKSQEI
                     MAFGDSENDVEMLEMAGIAYAMENADEKAKAVATALAPANSQGGVYQVLENWLEKGE"
     gene            complement(7298..7633)
                     /locus_tag="VYO11_000972"
     CDS             complement(7298..7633)
                     /locus_tag="VYO11_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="poly-gamma-glutamate biosynthesis protein"
                     /protein_id="HEV1595560.1"
                     /translation="MGNFISNQRIESMGDEENAKWTERGVLMDVTIKKKDGKTTIGTA
                     KAHPTWVNRTPKGTFSPEGYPLYHYQTYILEDFIEGGSHRDQLDEATKERIDTAYKEM
                     NEHVGLKWY"
     gene            complement(7634..8350)
                     /locus_tag="VYO11_000973"
     CDS             complement(7634..8350)
                     /locus_tag="VYO11_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CapA family protein"
                     /protein_id="HEV1595561.1"
                     /translation="MAHGDLLYHDGLFFSAKKEDGTYDFHENFEYVTPWLKQADLAIG
                     DFEGTINKDHYLAGYLLFNAPAEVMDAIKEAGYHVLDLAHNHILDSQIEGVISTADII
                     EKAGITPIGVYTHEQRDQAPLVIKEVNGIKVALLAYSYGFNGIEQYISQEDYNRYLLD
                     LNEDKMKAEVERAEKEADITIIMLQMGVEYRLEPTEEQKALYHKMIDWGADIIFGGHP
                     HVVEPSETVEKDGDKKLIIY"
     gene            8863..9474
                     /locus_tag="VYO11_000974"
     CDS             8863..9474
                     /locus_tag="VYO11_000974"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEV1595562.1"
                     /translation="MSAIERITKAAHLIDMNDIIREGNPTLRAIAEEVTFPLSDQEII
                     LGEKMMQFLKHSQDPVMAEKMGLRGGVGLAAPQLDISKRIIAVLVPNIVEEGETPQEA
                     YDLEAIMYNPKIVSHSVQDAALGEGEGCLSVDRNVPGYVVRHARVTVDYFDKDGEKHR
                     IKLKGYNSIVVQHEIDHINGIMFYDRINEKDPFAVKDGLLILE"
     gene            9519..10247
                     /gene="rlmB"
                     /locus_tag="VYO11_000975"
     CDS             9519..10247
                     /gene="rlmB"
                     /locus_tag="VYO11_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HEV1595563.1"
                     /translation="MKTNDIVYGVHAVTEALLANTGNKLYLQEDLRGKNVEKVKELAT
                     EKKVSISWTSKKSLSEITEGAVHQGFVLRVSEFAYSELDYILAKTRQEENPLLLILDG
                     LTDPHNLGSILRTADATNVSGVIIPKHRAVGVTPVVAKTATGAIEHVPIARVTNLSQT
                     LDKLKNEGFWTFGTDMNGTPCHKWNTKGKIALIIGNEGKGISSNIKKQVDEMITIPMN
                     GHVQSLNASVAAAILMYEVFRNRL"
     gene            complement(10286..11197)
                     /gene="trxB"
                     /locus_tag="VYO11_000976"
     CDS             complement(10286..11197)
                     /gene="trxB"
                     /locus_tag="VYO11_000976"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HEV1595564.1"
                     /translation="MYDTIIIGAGPAGMTAALYAARSNLKVALIEGGLPGGQMNNTSD
                     IENYPGYANISGPELAEKMFEPLENLGVEHIYGYVENVEDHGDFKKVMTDDQTYETRT
                     VIVATGSKHRPLGVPGEEELNSRGVSYCAVCDGAFFRDQDLLVVGGGDSAVEEALFLT
                     RFAKTVTIVHRRDQLRAQKVLQDRAFANEKISFIWDSVVREIKGENRVESVVFENVKT
                     GQVTEQVFGGVFIYVGLDPLGDFVKELNIQDQAGWIVTDNHMKTAVDGIFAVGDVRLK
                     DLRQVTTAVGDGAIAGQEAYKFITEHS"
     gene            complement(11263..11487)
                     /locus_tag="VYO11_000977"
     CDS             complement(11263..11487)
                     /locus_tag="VYO11_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4059 family protein"
                     /protein_id="HEV1595565.1"
                     /translation="MLLQLFSLYFESLILTTILVLIFLGIWIGLRAMSGVDKTARARQ
                     AHLYDMIMIGVLVVPVLSFAVMSLILVFKA"
     gene            complement(11565..12308)
                     /locus_tag="VYO11_000978"
     CDS             complement(11565..12308)
                     /locus_tag="VYO11_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV1595566.1"
                     /translation="MIKISNLSKSFSGQTVLDHLDLDIQKGEVVALIGSSGAGKSTFL
                     RSLNYLETPDSGSIQIDGFSVDFSKITQEEILALRRKLSMVFQQFNLFERRTALDNVK
                     EGLVVVKKLSDQEATKIAKEELAKVGLSDRENHYPRHLSGGQKQRVALARALAMKPDV
                     LLLDEPTSALDPELVGEVEKSIADAAKSGQTMILVSHDMSFVAQVADKILFLDKGKII
                     ESGTPDEIIHTPKEERTKEFFASYKRTYI"
     gene            complement(12308..13108)
                     /locus_tag="VYO11_000979"
     CDS             complement(12308..13108)
                     /locus_tag="VYO11_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001103446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV1595567.1"
                     /translation="MNVTTILASDWYQNLMQLIPDGKLFSLRSVFDGIPRIVQQLPTT
                     IMLTIGGALFGLVLALLFAIVKINRVKILYPLQAFFVSFLKGTPILVQLMLTYYGIPL
                     ALKALNQQWGTGLNINAIPAAAFAIVAFAFNEAAYASETIRAAILSVNPGEIEAARSL
                     GMTRAQVYRRVIIPNAAVVATPTLINSLIGLTKGTSLAFSAGVVEVFAQAQILGGADY
                     RYFERFISVALVYWVVNIGIESLGRFIERKMAISAPDTVQTDVKGDLR"
     gene            complement(13266..13622)
                     /locus_tag="VYO11_000980"
     CDS             complement(13266..13622)
                     /locus_tag="VYO11_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HEV1595568.1"
                     /translation="MLEFIEYPKCSTCKKAKQELNQLGVDYKAVHIVEETPSQEVILN
                     WLETSGFELKQFFNTSGIKYRELGLKDKVGSLSNQEAAELLASDGMLLKRPILVENGT
                     VKQIGYRKSYEELGLK"
     gene            complement(13616..14146)
                     /locus_tag="VYO11_000981"
     CDS             complement(13616..14146)
                     /locus_tag="VYO11_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HEV1595569.1"
                     /translation="MQKKYVKILYSSPIGILSLVADDHYLYGIWVQEQKHFERGLGDE
                     TIEEVVSHPILDPVIACLDDYFKGKPQDLSNLLLAPIGTNFEKRVWDYLQGIPYGQTV
                     TYGQIAQDLQVASAQAIGGAVGRNPWSILVPCHRVLGAGKRLTGYAAGVEKKAWLLEH
                     EGVDFKDRNNRRRSTC"
     gene            complement(14146..14640)
                     /locus_tag="VYO11_000982"
     CDS             complement(14146..14640)
                     /locus_tag="VYO11_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1595570.1"
                     /translation="MEIRLAFPNEVDAIMQVMEDAKKCLADAGSDQWQNGYPNADVII
                     DDIISGQAYVALEEGELLAYAAVTKSPEEAYEAIYEGNWQAGESEYLVFHRIAVAADV
                     QGKGVAQTFLEGLIEGFDYLDFRSDTHAENKVMQHIFEKLGFKQVGKVPVDGERLAYQ
                     KLKK"
     gene            14775..15221
                     /locus_tag="VYO11_000983"
     CDS             14775..15221
                     /locus_tag="VYO11_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HEV1595571.1"
                     /translation="MKTTFSYPKWAEIPNIDLYLDQVLLYVNQVCAPISPNKDKGLTA
                     SMVNNYVKNGYLTKPDKKKYQRQQIARLIAITTLKSVFSIQEIAQTLNTLQTQASSDQ
                     LYDAFVDYMNQGIDPANPIIQTSCQTVKLYHQTLDLIDHTQEEVIQ"
     gene            15218..15865
                     /locus_tag="VYO11_000984"
     CDS             15218..15865
                     /locus_tag="VYO11_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001097995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HEV1595572.1"
                     /translation="MNTSLKLSKQLSFGEEIANSVTHAVGAVIMLILLPISSIYSYEA
                     HGFLSSIGVSIFVISLFLMFLSSTIYHSMAYGSTHKYVLRIIDHSMIYVAIAGSYTPV
                     VLTLMNNWFGYLIIVIQWGTTIFGILYKIFAKKVNEKFSLALYLIMGWLVLAIIPAII
                     SQTTPVFWSLMVTGGLCYTVGAGFYAKKKPYFHMIWHLFILTASVLQYIAIVYYM"
     gene            complement(15886..16467)
                     /gene="pdxT"
                     /locus_tag="VYO11_000985"
     CDS             complement(15886..16467)
                     /gene="pdxT"
                     /locus_tag="VYO11_000985"
                     /EC_number="3.5.1.2"
                     /EC_number="4.3.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase glutaminase
                     subunit PdxT"
                     /protein_id="HEV1595573.1"
                     /translation="MKIGILALQGAFAEHAKVLDQLGVESVELRNLDDFQQDQSDLSG
                     LILPGGESTTMGKLLRDQNMLLPIREAILSGLPVFGTCAGLILLAKEITSQKESHLGT
                     MDMVVERNAYGRQLGSFYTEAECKGVGKIPMTFIRGPIISSVGEGVEILATVNNQIVA
                     AQEKNMLVSSFHPELTDDVRLHQYFINMCKEKS"
     gene            complement(16468..17343)
                     /gene="pdxS"
                     /locus_tag="VYO11_000986"
     CDS             complement(16468..17343)
                     /gene="pdxS"
                     /locus_tag="VYO11_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012054698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase lyase subunit
                     PdxS"
                     /protein_id="HEV1595574.1"
                     /translation="MTENRYELNKNLAQMLKGGVIMDVQNPEQARIAEAAGAAAVMAL
                     ERIPADIRAAGGVSRMSDPKMIKEIQEAVSIPVMAKVRIGHFVEAQILEAIEIDYIDE
                     SEVLSPADDRFHVDKKEFQVPFVCGAKDLGEALRRIAEGASMIRTKGEPGTGDIVQAV
                     RHMRMMNQEIRRIQNLREDELYVAAKDLQVPVELVQYVHEHGKLPVVNFAAGGVATPA
                     DAALMMQLGAEGVFVGSGIFKSGDPVKRASAIVKAVTNFRNPQILAQISEDLGEAMVG
                     INENEIQILMAERGK"
     gene            complement(17495..18874)
                     /locus_tag="VYO11_000987"
     CDS             complement(17495..18874)
                     /locus_tag="VYO11_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HEV1595575.1"
                     /translation="MSKIVVVGANHAGTACINTMLDNFGNENEIVVFDQNSNISFLGC
                     GMALWIGEQIDGAEGLFYSDKDKLEAKGAKVYMNSPVLSIDYDNKVVTAEVEGKEHKE
                     SYEKLIFATGSTPILPPIEGVEIVKGNREFKATLENVQFVKLYQNAEEVINKLSDKSQ
                     HLDRIAVVGGGYIGVELAEAFERLGKEVVLVDIVDTVLNGYYDKDFTQMMAKNLEDHN
                     IRLALGQTVKAIEGDGKVERLITDKESFDVDMVILAVGFRPNTALADGKIELFRNGAF
                     LVDKKQETSIPGVYAVGDCATVYDNARKDTSYIALASNAVRTGIVGAYNACGHELEGI
                     GVQGSNGISIYGLHMVSTGLTLEKAKAAGYNATETGFNDLQKPEFMKHDNHEVAIKIV
                     FDKDSREILGAQMVSHDIAISMGIHMFSLAIQEHVTIDKLALTDLFFLPHFNKPYNYI
                     TMAALTAEK"
     gene            19169..20092
                     /locus_tag="VYO11_000988"
     CDS             19169..20092
                     /locus_tag="VYO11_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HEV1595576.1"
                     /translation="MTLRSHSERLMGTTITISLVDEQADIFLQKSFDLLKELEYRFNA
                     NSQESELMEINYQAGISPVTVHPDLFELISLGLEHSLALSSHLNISIGPLIQTWRIGF
                     SDAKVAQPQEIESVLPLINPHGIELDSSTSTVFLKQKGMKIDLGCLAKGYSADKVAQF
                     LRKEGVTSALINLGGNILTIGKNQARGDNPWQIGIQDPANPRGNHLMTIPVVNKSVVT
                     SGIYERHLTVDGQDYHHIFDSQTGYPVETELASLTIISDKSVDGEIWTTRLFGERPAS
                     ILWQVESLEGIEVILIDKEGHLSCSSGIPTL"
     gene            20152..20757
                     /locus_tag="VYO11_000989"
     CDS             20152..20757
                     /locus_tag="VYO11_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEV1595577.1"
                     /translation="MLKLIAIVGTNSKRSTNRQLLQYMQKHFADKAEIELVEIKTIPV
                     FNKPADKQVPAEILEISAKIEEADGVIIGTPEYDHSIPAVLMSALAWLSYGIYPLLNK
                     PIMITGASYGTLGSSRAQLQLRQILNAPEIKANVLPDEFLLSHSLQAFNPSGDLVDLD
                     VIKKLDAIFDDFRIFVKITEKLRNAQELLRKDAEDFDWENL"
     gene            20776..22020
                     /locus_tag="VYO11_000990"
     CDS             20776..22020
                     /locus_tag="VYO11_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000673688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEV1595578.1"
                     /translation="MKFVGLVGSNYDQSYNRKLLEFIRRYFKLKFELEVLEIDEVPMF
                     NQDEKWDESFQLRYLYNKITRADGVIIATPEHNHTISASLKSVLEWLSYEVHPFENKP
                     VMIVGASYYDQGTSRAQVHLRKILDAPGVNAYTLPGNEFLLGKAKEAFDNNGNITNEG
                     TVKFLETCLDNFVKYVGVVSKLKKPKPIESEDLDCGKPIATTITEVDPDDPEWVEKVA
                     AITGAVSGDTYVKLDHGILTVNQIDMFLKAMPFELTYADDNNQFLYYNNAHQDPDTMF
                     AKRVPPQSGSRMSTVHGSLPPARMKNVEWVIGTLRNGNQEYVRTIVPGSPAGVINTHN
                     YQAMYYPDGSYAGINEIVFNFQPWLDWYLKETGQRLVGGSGPFAPAAGGHGDADATSG
                     ASDSGDAGGHGGDADATAGASY"
     gene            complement(22137..22394)
                     /locus_tag="VYO11_000991"
     CDS             complement(22137..22394)
                     /locus_tag="VYO11_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002901318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HEV1595579.1"
                     /translation="MDPKKIARINELAKKKKTEGLTPEEKVEQAKLREEYIEGYRRAV
                     RHHIEGIKIVDEEGNDVTPEKLRQVQREKGLHGRSLDDPNS"
     gene            complement(22436..24472)
                     /locus_tag="VYO11_000992"
     CDS             complement(22436..24472)
                     /locus_tag="VYO11_000992"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HEV1595580.1"
                     /translation="MTKNLLVELGLEELPAYVVTPSEKQLGEKMAAFLKENRLSFEAI
                     QTFSTPRRLAVRVTGLSDKQSDLTEDFKGPAKKIALDSDGNFTKAAQGFVRGKGLTVE
                     DIEFREIKGEEYVYVTKEEVGQSVEAIVPGVVDVLKSLTFPVSMHWAGNSFEYIRPVH
                     TLTVLLDEQEFDLDFLDIKGSRVSRGHRFLGKETKIQSALSYEEDLRKQFVIADPCER
                     EQMIVDQIKEIEAKHGVRIEIDADLLNEVLNLVEYPTAFMGSFDAKYLEVPEEVLVTS
                     MKEHQRYFVVRDQDGKLLPNFISVRNGNAERLKNVIKGNEKVLVARLEDGEFFWREDQ
                     KLVISDLVEKLNNVTFHEKIGSLREHMIRTGQITVLLAEKAGLSVDETVDLARAAAIY
                     KFDLLTGMVGEFDELQGIMGEKYTLLAGETPAVAAAIREHYMPTSAEGELPESKVGAV
                     LAIADKLDTILSFFSVGLIPSGSNDPYALRRATQGVVRILDAFGWHIAMDELIDSLYA
                     LKFDSLTYENKAEVMDFIKARVDKMMGSTPKDIKEAVLAGSNFVVADMLEAASALVEV
                     SKEEDFKPSVESLSRAFNLAEKAEGVATVDSELFENDQEKALAEAVETLVLSGPASQQ
                     LKQLFALSPVIDAFFENTMVMAEDQAVRQNRLAILSQLTKKAAKFACFNQINTK"
     gene            complement(24684..25601)
                     /gene="glyQ"
                     /locus_tag="VYO11_000993"
     CDS             complement(24684..25601)
                     /gene="glyQ"
                     /locus_tag="VYO11_000993"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018163989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HEV1595581.1"
                     /translation="MSKKLTFQEIILTLQQFWNDQGCMLMQAYDNEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPSNIQELYLESLEK
                     LGINPLEHDIRFVEDNWENPSTGSAGLGWEVWLDGMEITQFTYFQQVGGLATGPVTAE
                     VTYGLERLASYIQEVDSVYDIEWADGVKYGEIFIQPEYEHSKYSFEISDQEMLLENFD
                     KFEKEAGRALEEGLVHPAYDYVLKCSHTFNLLDARGAVSVTERAGYIARIRNLARVVA
                     KTFVAERKRLGYPLLDEETRAKLLAEDAE"
     gene            complement(25794..26555)
                     /locus_tag="VYO11_000994"
     CDS             complement(25794..26555)
                     /locus_tag="VYO11_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HEV1595582.1"
                     /translation="MDNLYLVKDDSQLATFRDFVVRNTEKLKDYQSFLKNELAVCDLP
                     QAVIWSDFNAATQIIRESAVPAYTNNRRMVMAPDLAVWKELYLYQLMDYECSQQTQAI
                     ESHYHSLSENFLLQIVGHELAHWSEHFLDDFDGYDSYIWFEEGMVEYISRKYFLTEEE
                     FQAEKICNQSLVELFQKKYGWHSLNDFGSSTYDKNYASIFYEYWRSFLTVDKLVENLG
                     SVQAVLDSYHLWANTEKTFPLLDWFVQQKLIEKEI"
     gene            complement(26828..27670)
                     /locus_tag="VYO11_000995"
     CDS             complement(26828..27670)
                     /locus_tag="VYO11_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HEV1595583.1"
                     /translation="MNTYQLNNGVEIPVLGFGTFKAKDGEEAYRAVLEALKAGYRHID
                     TAAIYQNEESVGQAIKDSGVPREEMFVTTKLWNSQQTYEQTRQALEKSIEKLGLDYLD
                     LYLIHWPNPKPLRENDAWKTRNAEVWRAMEDLYQEGKIRAIGVSNFLPHHLDALLETA
                     TIVPAVNQVRLAPGVYQDQVVAYCREKGILLEAWGPFGQGELFDSKQVQEIAANHGKS
                     IAQIALAWSLAEGFLPLPKSVTTSRIQANLDCFGIELSHEERENLKTIAVQSGAPRVD
                     DVDF"
     gene            complement(27784..29175)
                     /locus_tag="VYO11_000996"
     CDS             complement(27784..29175)
                     /locus_tag="VYO11_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013193417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HEV1595584.1"
                     /translation="MNKSRLGRGRHGKTRHVLLALIGILAISICLLGGFIAFKIYQQK
                     SFEQKIESLKKEKDDQLSEGNQKEHFRQGQAEVIAYYPLQGEKVISSVRELINQDVKD
                     KLESKDNLVFYYTEQEESGLKGVVNRNVTKQIYDLVAFKVEETEKTSLGKVHLTEDGQ
                     PFTLDQLFSDASKAKEQLIKELTSFIEDKKIEQDQSEQIVKNFSDQDLSAWNFDYKDS
                     QIILYPSPVVENLEEIALPVSAFFDVIQSSYLLEKDAALYQSYFDKKYQKVVALTFDD
                     GPNPATTPQVLETLAKYDIKATFFVLGKNVSGNEDLVKRIKSEGHVVGNHSWSHPILS
                     QLSLDEAKKQITDTEDVLTKVLGSSSKLMRPPYGAITDDIRNSLDLSFIMWDVDSLDW
                     KSKNEASILTEIQHQVANGSIVLMHDIHSPTVNALPRVIEYLKNQGYTFVTIPEMLNT
                     RLKAHELYYSRDE"
     gene            complement(29410..29787)
                     /locus_tag="VYO11_000997"
     CDS             complement(29410..29787)
                     /locus_tag="VYO11_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001833802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
                     /protein_id="HEV1595585.1"
                     /translation="MICQFIRDMLDLPAKNVTILEGSNIHVLPSMPYSAQDFYTSIDV
                     LAELDNGIQVIIEIQVHHQNFFINRLWAYLCSQVNQNLEKICQREGDTHQSYKHIAPV
                     YAIAIVDSNYFSDDLAFHSFIVK"
     gene            30020..30997
                     /locus_tag="VYO11_000998"
     CDS             30020..30997
                     /locus_tag="VYO11_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEV1595586.1"
                     /translation="MLKLGVIGTGAISHHFIEASHTSGEYQLVAIYSRKLETAATFAS
                     RYQNIQLFDQLEVFFKSSFDLVYIASPNSLHFAQAKAALSAGKHVILEKPAVTQPQEW
                     FDLIQTAEKNNCFIFEAARNYHEKAFTTIKNFLADKQVLGADFNYAKYSSKMPDLLAG
                     QTPNVFSDRFAGGALMDLGIYPLYAAVRLFGKANDATYHAQQLDNSIDLNGDGILFYP
                     DYQVHIKAGKNITSNLPCEIYTTDGTLTLNTIEHIRSAIFTDHQGNQVQLPIQQAPHT
                     MTEEVAAFAHMIQQPDLNLYQTWLYDAGSVHELLYTMRQTAGIRFEAEK"
     gene            30994..32076
                     /locus_tag="VYO11_000999"
     CDS             30994..32076
                     /locus_tag="VYO11_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEV1595587.1"
                     /translation="MKTKLPTEWQELSDQLGFQEFTPIQTQLFEPLLAGENLLGVSKT
                     GTGKTLAYLLPSLLRLQKKKAQQLLILAPNTELAGQIFDVCKTWAEAIGLTAQLFLSG
                     SSQKRQIERLKKGPEILIGTPGRIFELIKLKKIKMMNVETIILDEFDQLLDDSQIHFV
                     EKITHYAPRDHQLIYMSATTKFDQEKIVPNTRTIDLSDQKLDNIQHFYMQVDQRHRVD
                     MLRKLAHVEDFRGLVFFNSLSDLGNAEEKLQYRDILAVSLASDVNVKFRKVILEKFKD
                     NQLTLLLATDLLARGIDIDSLECVVNFDIPRDSETYTHRAGRTGRMGKEGYVITLVTH
                     PEEIKKLKKFASIREIVLKNQELYIK"
     gene            complement(32140..>32525)
                     /locus_tag="VYO11_001000"
     CDS             complement(32140..>32525)
                     /locus_tag="VYO11_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV1595588.1"
                     /translation="DAHTGASVFLIAGGCNTEWMNVFLEELSQAYPYDYFLLVIDNAI
                     WHKSSTLKIPTNIGFAFIPPYTPEMNPIEQVWKEIRKRGFKNKAFRTLEDVMNQLQDV
                     IQGLEKEVIKSIVNRRWTRMLFESR"
BASE COUNT         9704 a         7249 c         5833 g         9739 t
ORIGIN      
        1 aaaaatggag ttcccctttc agatgtttgg aatataccat ttcttaatcc aaaagctaaa
       61 gaaagagtag gttatcctac acaaaaacct attctgttat tagaacaaat tataaagatt
      121 gctactgata aaaatgatat agttttagac ccgttctgtg gaagtggaac tactttagta
      181 gcctccaaga ttttgaatag aaattatatg gggattgatt tatctgagga agctatcaat
      241 ataactcagc aacgtctgga aaatgttata aaaacaagtt caaatttatt gaataaagga
      301 atcgaagcat atagaaccaa aactgaggaa gaggaaaaca ttcttaaatt attacaggca
      361 aaaattgttc aaagaaataa aggaattgat ggttttttac ctaaacattt tcaaaaaaaa
      421 ccgataccta taaaaattca aaaaaataat gaatgtctga atgagagtat ctctttatta
      481 cagaatgcta taaactccaa aaaacttgat tttggagtag ttataaaaac tcattcagat
      541 aatttattat ttgattttga tacgattcct gaaaatataa tagtagttga ccattttgaa
      601 cttacaatcg aaaaatggtt aagtaaaagt caacagttac tatagtttgc aaattattta
      661 cagaaagaac aaaaaatgct ctgaaacact gatttcaaag cattttttgt tagtttaaaa
      721 ttactcccac tcaactgttg caggtggttt acttgtaata tcgtagacga tacggttaac
      781 atgatccact tcatttacga tacgtactga gattttttga agtacttccc atggaatttt
      841 ggcaaaatca gcagtcatac catcgataga agtgatagca cggattgcaa tcgtgtagtc
      901 atacgtacga ccgtcaccca taacaccgac tgaacgaacg cctgtgttaa cagtgaagta
      961 ttgccaaata tcgcggtcaa gtccagcttt agcgatttct tcacgaagaa tagcgtctga
     1021 ttcacgaacg gtttcaagtt tctcttcagt gatttcaccc atgacacgga tagcaagtcc
     1081 tggtcctggg aatggttggc gccatacgat atggtctggc ataccaagct ctgtaccaag
     1141 agcacgaact tcatccttgt aaagagtatt aagtggttca atcaattcaa actgcatatc
     1201 ttctggaaga ccacccacgt tgtggtgtga cttgatagtt tgagctgtat ccgtaccaga
     1261 ctcgataaca tctgtgtata aagtaccttg agcaaggaat ttcacatctt tgagcttgct
     1321 tgcttcgtca tcgaatacat agacaaactc gttaccgatg attttacgtt tttgttcagg
     1381 atcagaaacg ccagcaagtt tgtcaaggaa acgtttagca gcgtctgctt tgacgatatt
     1441 caaaccaaac ttaccaccga gcatgtccat aacttgatca gcttcgcctt tacgaagaag
     1501 accgtggtct acgaagatac agatcaattg atcgccaatc gctttttgga gaagaacccc
     1561 aacgacagat gagtcaacac cacctgatag accaagaagg acacgtttat caccgacggt
     1621 ttcacgaatt tttttgatct gcatgtcaat gaaattatcc attgaccagt cacctttagc
     1681 cttacaaatg ttaagggcaa agttacgaag gatatcattt ccgtatacag aatgacgaac
     1741 ttctgggtgg aattggatac cgtaaatgtg tttatctggg ttttcgatgg ctgcgtatgg
     1801 gcagtcagct gatgtacctg tacgaacaaa gtcagcagga atctcagtaa ccgcatcacc
     1861 atggctcatc aaaacagtct gttcatcagg tgttgattca aaaagcgctg atggtgtgtg
     1921 agttagggtt gattgaccgt attcacgatt tccagcatca cctgcaggaa caacttttcc
     1981 tccaagttta tgggtcaata actgcatacc ataacagatt cccaaaattg gaattccgag
     2041 ttcgaagatt tctgggtcaa tatcaaatga accatcttca tatacagaat ttggaccacc
     2101 tgatagaata attcctacag gattgacttc acgaacttca gcagctgaaa ttttatggct
     2161 ttttagttct gaaaaaacac caatctcacg gatacggcgt gaaatcagct ggttgtactg
     2221 gctaccatag tccaatacga tgattttttc tacatcttgc aaatcagttg aaatgttgct
     2281 catctttttc ctttctcaaa agaaatatct tttctcaata ttctatcaca aataagggcg
     2341 aattaccaac taaacaaggc gaagtttgac tttttctagt ttattggggt acaatagaga
     2401 aaagatagaa atgaagtgaa aaatatgcta cctgcttata tgaaaatcca tgatcagata
     2461 aaaaaggata ttgacgagca ccgttgggct attggtgaga ggcttcccag tgaaagagat
     2521 ttagctgagc agtttgcggt cagtcgcatg accctccgcc aagccgtatc tctattagtc
     2581 gaagaaggcg tcttagagcg ccgtgtagga agcggcacct ttgtttccag tactcgagta
     2641 caagaaaaga tgcgagggac aaccagtttt actgaaattg tcaaatccca aggtaaagtt
     2701 ccctctagcc agctcatttc ctacaaaaaa accattccca atgagcaaga agttgccaag
     2761 ctaggaattt ttccaacgga caatattatc cgaatggagc gggtccgcta tgccgaccaa
     2821 gttcccctag tttatgaagt tgcttctatt cctgaaaaat tcattaagga ctttaaaaaa
     2881 gaagaaatca ccagtcattt cttccaaacc ttgcagaaac atggctatcg tatcggcaaa
     2941 tctcaacaga ccatctatgc tcgccttgct aaagaaaaga ttgcccacta tttggaagtt
     3001 gaaaaaggac atgctattct tggattgaca caggtttcct acctagaaga tggtactgct
     3061 tttgaatacg taaaaagtca atatgtaggc gaacgctttg aattttatct tgaaaataat
     3121 tagattacca cgcaaaaact ctctgtcaca gacaaagagt cttttttatt tttctaagaa
     3181 taaatctttc aaagaaatca aagttacagc aaacaatatc attgccatac caagaaaatc
     3241 aatgggataa aattgttcat tcattattaa gaaggcaaag aaaaccgccg atattggctc
     3301 aattgaagcc aacaagcttg acttgaccgg tcctatcaga ctggctcctt taaggaaagc
     3361 tgtataggca aagacagtcc cgataaggat aatgcctgca aacgcaagga gaaaatcaag
     3421 actagtcggg atattggcct gtagaacccc tgtaaaagga agggcgacca aacctgctat
     3481 aaccattccc acaccaatga ccaagctact cccccacttt ttaatcaagg ctatgggtaa
     3541 aatgatatat agagcataag tcaaggcaga aaagagaccc cagaacaggc cagcaggtgt
     3601 catggataac tggtccaact gcccatgtgt tgcgatcagg aaggttcctc cgatggcgaa
     3661 tatgatggaa actatctctc ccagtgtcgg tgccacccta tccttgatac agctataaat
     3721 taaaattccg acaggacaaa catactgaag caccgtcgct gttcccgcat tggtctcctg
     3781 aatagcagac agataggcga attggttgag aaaaagacca atcagagcaa aaataagaag
     3841 agacagcaaa ctctttctat cctttaaaaa gaccagtatt ttatcctttg cagtagcata
     3901 agacaagagc atgagaattc caccagcgat taaaagacgc aagttggtca agaccagagc
     3961 cgaaattccg tgtgccatta ggtattggcc actcgttcct gacaaccccc aagcaatacc
     4021 agccacaact gttagtaaag tcccttttaa actatttgac atgtctctcc ttactcttct
     4081 ttgcgaatca agttcatcac ttgattgcgg tctaatatcc attgagctct ctcgtccttt
     4141 tcataggtac gattcgatag gaaaatagtg gcttcttgct tctgacgatt ccacatgata
     4201 aaggtacctg tatagcccgt atggtctagc caatctcctt ccaaattcca tgctaaagaa
     4261 cgttccttgt catccaaagg agaaaaattt tgatttaagt ctcttgcaaa atcatctgct
     4321 aaatagtgtt ctaaaaaggt ttgtaaatcc tttatagtcg aaaataaacc agcactccca
     4381 gcatgtctac ccaggagacg agccttggga tcatgcacta tgcctgcctc tacacctcta
     4441 actgttggaa cagcaagctc aactggccca aacttagttt ccgtcattcc ccaaggtttc
     4501 cagacttgat cctttaaaat cacatccaaa tcttgattaa aaattctttc caaaataaag
     4561 cccaacagca aaaaatggac atccgaataa agaaaggctg gctgacttcg tctgttgaga
     4621 tgaaacatcg cttcctttaa ttcaggggct gttaaaagat cacgattagg aataaaagga
     4681 tcaaggtctg ttgcatgagt caagagctgg cgaatagtga tgtctggata atcactctca
     4741 ggtaaaaaat ctattaccag tctatcaata tctaattgac ctatttccca caagaaggta
     4801 caaactgtgc caaccccaac aaccttactg acactagcta ggtcataaac tagtcctgcc
     4861 tcagtctgca agccatgctc tgggtcactc tggcctgaat agaactctgt ccattgattg
     4921 tccttaaaat acgcaaaaga ggctccggga taaatccctg cctcgatttg ttcttctatt
     4981 tttttaataa tcttggtcca cttcatactt cttcaaacca caattcaaca ttatttctat
     5041 ctttaccaag gaagaatttt tcagacttag gaataaaata ttcagtagac tcaaacttct
     5101 ggcgaagact tgctatgtct aattcattga ccaagaactt gagcatagat aagtcccagg
     5161 taaccgtatt gtccacagtc aaatcctgcc cctgagctgg aataaaatca agggatgccc
     5221 caatttcaga tgattccaag aaactttcga tatcagttgg gagatgtaat tccatagaaa
     5281 tctcaaattt acttaaagaa attgatgcca aatctgtttg aaattcaggc ttttctccta
     5341 cttctactag acttgctctg tcatcttccg catgaatcaa aatcaaatca tcttctggtg
     5401 agaaaatttc aaaagcgtag ccattttgac ctttatataa tcgatgaatc gaatctgttt
     5461 tagataagat tccttcaatt tctaagggat tttccacctt gacaatcaat ctagctagtt
     5521 tttttcttcc ctctacctta cgagtacgca tactgggagc ttcttctaaa accagctttt
     5581 caagacccgt ttggtcacct agtgacagaa aggccgattc ttctaacaag gccttcattc
     5641 caagggtttc aatataaaat gtttcattta attttctatt attagctttt aaagtaggaa
     5701 taatccgtac aatctgattt acattcataa attcctccgt cactttttat tttaaaggat
     5761 tttagaattt tttacaagat attatgctca aatttcacat tatttagcta tttagtaaag
     5821 atagtctttc aaggcttttg acaaagcctg ataaccagca atactgaggt gcagtccatc
     5881 agttgtatat tcttttttga gttggcctgc ttggtctgtc aaacaatcaa atactggcac
     5941 aaattccacc tgcatatagg cagatgcaag atcttgatag gcttgattcc agttctgaat
     6001 tttttcattc gagcggatat agactgcctg ctgatactcc tctccctcat tgacaggtaa
     6061 aatggaaagc aatttaatct ctgtcaatgg ataatcgcga gcaacggatt gaatgatagc
     6121 ttcgagatta ttgagagcct cattcacagg aacatccttt ccgatatcat ttgtcccaat
     6181 cagaagaaaa attttatcta ctgctccacc atatagatga gcatcaaggt tctctagtaa
     6241 cagtcctgtc tgatagccac gaattcctcg attgacaatc atttttgaag tcccaaatag
     6301 ctcctgtaga ggataatact cgacaatgga atccccaata aaaagaatgt ttggttctac
     6361 aacagaaatg tgatttaggt gacgatactt ggtttgaatt ttttcttgtt cctttaggag
     6421 ccaattttct aataactgta ctgccacttc attctccttt ttctaaccag ttttccaaga
     6481 cttgataaac tcctccttgg ctattggctg gtgctagagc agtcgccaca gctttggctt
     6541 tctcatcagc attttccatc gcataggcaa ttccagccat ttcaagcatt tcaacatcat
     6601 tttcactatc accaaaagcc atgatttctt gggatttcaa gtcccagcgc ttgagtaatt
     6661 cctccaagcc ccatgcttta tgaatcccag cttggaggat atcaatgcaa ccatagccac
     6721 tggatacagc tcggacacgg ccatcaaaga gagcattgat ttcttccaaa accgaactca
     6781 aacgttcctc accaacaacc atgctcatct tgagcacacc accaaagagg tcagatgtta
     6841 attcatccac aaattgcatc cgttggtaga atttttcaat catttctgga gtcataaaac
     6901 tttcaagatc tgtaaaaatc gtaccttcct tgacaaaatc acccttcatc cccgttacaa
     6961 caaactggtc ctgacacgct cgacccttga aatgagccaa agccttgttg acaatggcgt
     7021 catcccatgt ctgagcctga atcaattcat tgttttcaaa aatacgagcg ccattagcaa
     7081 caaccagaac cactcgatcc accaagggac tcagtagttg tctcatgcgg tgaatttcat
     7141 tgcccgtcgc aatgacaaaa cgaatgcccc tttgatccaa ctgatctaaa atcttttcca
     7201 atcgtgggag atcaagctga cctctagcat ccagcaaggt cccatccata tctgtcgcaa
     7261 ttatcttaat catcatttac tttcctctgg attcaagcta ataccacttc aatcccacat
     7321 gttcattcat ttctttatag gctgtatcaa ttcgttcctt agtcgcttca tctaactggt
     7381 cacgatgact gccaccctct ataaaatctt ccaaaatata agtttggtaa tgatacaagg
     7441 gatatccttc tggtgaaaag gttccctttg gtgttcgatt gacccaagta ggatgagctt
     7501 tagctgttcc gatagttgtt tttccatcct tcttcttgat ggtgacatcc atgagaacac
     7561 cacgttcagt ccacttagca ttctcttcat ctcccataga ttcaatccgt tgattggaaa
     7621 tgaagttccc catttaatag ataatgagtt tcttatctcc atctttttca accgtttcag
     7681 atggttcaac aacgtgagga tgccctccaa agataatatc cgctccccaa tcgatcatct
     7741 tgtgataaag agctttttgt tcttcagttg gttccaatcg atactcaaca cccatctgaa
     7801 gcatgataat ggtgatatct gcttccttct ctgcccgttc aacttcagcc ttcatcttat
     7861 cttcgtttaa atctaaaaga taacgattat agtcttcctg agaaatatac tgctcaattc
     7921 cattgaaacc ataggaatag gctaacaatg caaccttgat accattcact tccttaatga
     7981 ccagcggagc ctgatcacgt tgttcgtgcg tataaactcc gattggagtg attccagctt
     8041 tctcaataat atcggccgtt gaaataactc cctcaatttg cgaatccaaa atatgattat
     8101 gagctaaatc cagcacatga taacctgctt ccttaatagc atccataact tcagcaggag
     8161 cattaaagag aagataaccc gctaaataat gatccttatt aatggttcct tcgaaatcac
     8221 caatagctaa atctgcttgc ttgagccaag gagtcacata ctcaaaattt tcatgaaagt
     8281 cataggtacc gtcttctttt ttagctgaaa agaaaagtcc atcgtggtag agcaaatccc
     8341 cgtgggccat aattctggca gttttttcct cttcctactc ctgagacttt tgcttagtcc
     8401 cctcttgaga aatagtatct cgtttttgac tagtcaaggg attccttgga agctttcaaa
     8461 caacaagacc aagcccattg ataaaccaac tgctagcaag agtatcgcca caaatccctt
     8521 attgctccac ttgcgataac tcctaaaaag tttaccaagc ccttcataaa acgaaaagct
     8581 aaaccaccct gatttcgatt ttgtcttctt tgtatcttcg ttctccctac tttcttatgc
     8641 aagccttttc tttttattat atcacagata agtatttctt tcacaattga attgaacttc
     8701 ctatctattt tctataaatc ctaaatgcca taatgctttc aattcttgtc attttgtgat
     8761 atcatgtaga ggaaatgaac taatccacag tggcttattc caagtatacc acttgggctt
     8821 tggcagtagc taactgcact aaacataata taaggagaga aaatgtctgc aatagaacgt
     8881 attacaaaag ctgctcactt aattgatatg aacgatatta tccgtgaagg gaatcctact
     8941 ctacgcgcga ttgctgagga agtcactttc cccctatctg accaggaaat catcctaggc
     9001 gaaaagatga tgcaattcct taaacattcc caagatcctg tcatggctga aaaaatggga
     9061 ctccgcggtg gtgttggact ggctgctccc cagttagata tctcaaaacg cattatcgct
     9121 gttttggtac ctaatattgt tgaagaaggc gaaactccac aggaagccta cgatttggaa
     9181 gccattatgt acaatccaaa aatcgtctct cactctgttc aagatgctgc tcttggcgaa
     9241 ggagaaggtt gcctgtctgt tgaccgtaac gtgcctggct atgttgttcg ccatgcccgc
     9301 gttactgttg actactttga caaagatgga gaaaaacacc gtatcaaact caaaggctac
     9361 aactccattg ttgttcagca tgaaattgac cacattaacg gtatcatgtt ttacgatcgc
     9421 atcaatgaaa aagacccatt tgcagttaaa gatggtttac tgattcttga ataaagaaaa
     9481 tcccgttgca agacggggtt ttgtgttata atagaggcat gaaaacaaat gatattgtct
     9541 atggcgtcca cgccgttacc gaagccctcc ttgcaaatac aggaaacaaa ctctacctcc
     9601 aagaagatct ccgaggtaag aatgttgaga aagtcaagga actagctaca gaaaagaagg
     9661 tgtccatttc ttggacatca aaaaaatctc tctctgagat tactgaaggt gctgttcatc
     9721 aaggttttgt tctacgagtg tctgaatttg cctatagcga gctagattac atccttgcaa
     9781 aaacacgcca agaagaaaat ccacttctat tgattctaga tggtctaacc gatccccata
     9841 atctaggttc tatcttgcga acagccgatg cgaccaatgt ttcaggtgtc atcattccca
     9901 agcaccgtgc tgtcggagta actcctgtcg ttgccaaaac agccacaggt gctattgaac
     9961 acgttccaat tgcccgagtg accaacctca gtcaaacctt agataaactt aagaatgaag
    10021 gtttctggac ctttggaacg gatatgaacg gtactccttg ccacaagtgg aatacaaaag
    10081 ggaaaatcgc cctcatcatt ggaaatgaag gaaaaggtat ctctagcaac ataaaaaaac
    10141 aggtcgatga aatgattacc attccgatga atggacatgt tcaaagcctt aatgccagtg
    10201 ttgctgcggc cattctcatg tacgaagttt tccgaaatag actataaaaa agtttccagt
    10261 catctgattg gaaacttttt tatgattaac tatgttctgt aatgaattta taggcttctt
    10321 gaccagcgat agctccatct ccaaccgctg ttgttacttg gcgaaggtct ttcaagcgaa
    10381 catctccaac tgcaaagata ccgtcgactg cagttttcat gtggttatct gtcacaatcc
    10441 atcctgcctg atcttggata ttcaattctt taacaaaatc gccaagaggg tccaatccaa
    10501 catagataaa gacaccaccg aagacttgtt ctgtcacttg acctgttttc acattttcaa
    10561 atacgactga ttctactcgg ttttcaccct tgatttccct tactacagaa tcccagataa
    10621 agctgatttt ttcattcgca aaggcgcgat cttgtaaaac cttttgggca cgaagttggt
    10681 cacgacggtg aacaatggta acagtcttag caaaacgagt caagaagagg gcttcttcaa
    10741 cagctgaatc tccaccacca actaccaata aatcttggtc acggaagaaa gcaccatcac
    10801 acacagcaca gtaagaaaca ccacgactgt tcagttcttc ttctccaggt actcccaaag
    10861 gacggtgttt agaaccagtt gctacgataa ctgtacgtgt ttcatatgtt tggtcatcag
    10921 tcatcacttt cttaaaatca ccatggtctt cgacattttc aacataacca taaatgtgct
    10981 ccacaccaag attttcaagt ggttcaaaca tcttttcagc caattcaggt ccactaatat
    11041 tagcgtatcc tgggtaattt tcgatatcag atgtattatt catctgacca cctggcagac
    11101 caccttcaat caaagctact tttagattgc ttcgagcagc atacaaggcc gcagtcatcc
    11161 ctgcaggtcc agcaccgata ataatagtat cgtacatata gattccttct ttcttgttgt
    11221 aactatcttt attctaactc tttcttgtca atcacgcaag gattatgcct tgaaaacaag
    11281 aattaaactc ataaccgcaa aggataatac tgggacaacc aagactccaa tcataatcat
    11341 atcatagaga tgggcttggc gagccctggc tgtcttatca actcccgaca tggctctcag
    11401 accaatccaa atccctaaaa aaatcagaac aaggatggtg gtcaagatca aactctcgaa
    11461 atataaagaa aatagttgca gtagcatgat ttctctcatt tctatctttt ttaaagagta
    11521 aactcagcta gtccaactaa ctgagttttc ctttatctat tatatcaaat ataagtccgt
    11581 ttgtaactag cgaagaattc ttttgtccgc tcttctttag gggtgtggat aatctcatcc
    11641 ggtgttccag actcgatgat tttcccctta tctaagaaga gaatcttatc agccacttgg
    11701 gctacaaagg acatgtcatg actaaccaaa atcatggttt gacctgactt agcagcatct
    11761 gcaatagact tttctacttc accaaccaat tctgggtcaa gggctgaagt tggttcgtct
    11821 aagagcaaaa catctggttt catagcaagc gcacgcgcta gggcaacccg ttgcttctgt
    11881 ccacctgata aatggcgagg ataatggttt tcacggtccg aaagcccaac cttagccaac
    11941 tcttccttgg caatcttagt cgcttcttgg tcagataatt tcttgacaac aaccaagcct
    12001 tctttcacat tatcaagtgc tgttcggcgt tcaaacaaat taaactgttg gaaaaccata
    12061 gacaacttac gacgtagggc aaggatttct tcttgagtga ttttagaaaa atcaactgaa
    12121 aaaccatcaa tctgaataga gccactgtca ggtgtttcaa gataattgag actgcgaaga
    12181 aaggttgatt ttccagctcc tgaagaacca atcaaggcta caacttcccc tttttgaata
    12241 tccaagtcca gatgatccaa gacagtctgt cctgaaaagg atttgcttaa atttgaaatc
    12301 ttaatcatta acgaaggtct cctttcacat ctgtttgcac tgtatcaggt gcagaaatag
    12361 ccatttttct ctcgatgaaa cgaccgaggc tttcaattcc gatattgacc acccaataaa
    12421 caagggcaac ggagatgaag cgttcaaaat agcgataatc agctccacct agaatctgag
    12481 cttgggcaaa gacttccaca acacccgcac taaaagctag agatgttccc ttggtcaaac
    12541 cgatgaggga attaatcaag gttggagtag ctaccaccgc tgcattagga ataatcactc
    12601 gtcgataaac ttgcgctcgg gtcataccca gactgcgtgc cgcctcaatc tcaccaggat
    12661 taactgagag aatggctgca cgaatggttt cactagcata agctgcctca ttaaaggcaa
    12721 aggcgacaat cgcaaaagct gcagctggaa tcgcattgat attgagacca gttccccatt
    12781 gctgattgag ggctttcaaa gccaaaggga ttccgtagta ggtcaacatg agttgcacca
    12841 aaatcggtgt cccttttaag aaactaacaa agaaggcctg caagggatat aaaatcttga
    12901 cacgattgat cttcacaatg gcaaaaagaa gcgccaaaac caagccaaaa agggcaccac
    12961 caattgtcaa cataattgtt gttggaagtt gttggacaat tctagggatt ccatcaaaga
    13021 ccgaacgtag gctaaacagc ttgccatccg gaatcaattg catcaagttt tggtaccaat
    13081 ctgatgctaa aatcgttgta acattcataa aaacatcctc ttctgataat gattcattct
    13141 accatgcttc tgccgtcaat gaaattattt gctacggtca gatacagact ttgtctacct
    13201 actagtttat catactttga aacagggaag ttatatattt tatctatcaa agagatagat
    13261 aaaaactatt tcagtcccag ttcttcataa gattttcgat aaccgatttg cttaacagtt
    13321 ccattttcta ctaaaatagg ccgttttaac aacataccgt cacttgctag caactcagcc
    13381 gcttcttggt ttgacaaact tcctacctta tcttttagcc ctaattcacg gtatttgata
    13441 ccactggtgt tgaaaaattg cttcaattca aatcctgagg tttctagcca attcaaaatg
    13501 acttcttggc taggtgtttc ttccacgata tggacggctt tatagtccac acctaattga
    13561 tttaattctt gttttgcttt tttacaagtt gaacatttgg ggtattcgat aaattctaac
    13621 atgtgcttct ccttctattg tttctatctt taaaatctac tccttcatgc tccaagagcc
    13681 aagctttctt ttccactcct gcagcataac ctgtcagacg cttgcctgct cccaacacac
    13741 gatgacaagg tactaggata gaccaaggat tgcgtcccac tgctccacca attgcttgag
    13801 cagaagccac ttgcaggtct tgagcaattt gtccataggt cactgtctga ccataaggaa
    13861 tgccctgtaa atagtcccaa actctctttt caaaattcgt tccgattggc gccaagagca
    13921 agttggataa atcctgaggc ttgcctttaa agtaatcatc taagcaagca ataactgggt
    13981 ctaaaatagg atgactaaca acttcttcta tcgtttcatc tcctagtccc ctctcaaaat
    14041 gcttctgctc ctgaacccaa attccataca aataatggtc atcagctaca agtgatagaa
    14101 taccaattgg tgaggagtag aggattttta catacttctt ttgcattatt tctttaattt
    14161 ttgataggcc aagcgttcgc catctactgg caccttacca acttgtttaa aaccaagttt
    14221 ttcaaaaata tgttgcataa ccttgttttc agcatgcgta tctgagcgaa aatcaagata
    14281 atcaaaacct tcaatcaagc cctctaagaa ggtttgagca actccttttc cctgcacatc
    14341 tgctgccaca gcaatacggt gaaagactag atactctgac tctccagctt gccagtttcc
    14401 ctcataaata gcttcatagg cctcctctgg actcttggtc acagcagcat aggctagcag
    14461 ttctccctct tccaaggcta cgtaggcttg ccctgagatg atatcatcga taataacatc
    14521 tgcatttgga tagccatttt gccactggtc actaccagca tctgctaaac attttttggc
    14581 atcctccatc acctgcatga tggcatctac ttcatttgga aaagctaaac gaatttccat
    14641 cttttttcct catttctgac tagtttctcc catcatagca taatttaagt atttctacaa
    14701 gcagttaaaa cttgactttg tgtttttgtt attttataat ctagttatca aaactatata
    14761 aaaaggagtt gaaaatgaaa actacctttt cctacccaaa atgggcagaa attccaaaca
    14821 ttgacctcta tctggaccag gttttgctct atgtcaatca ggtctgcgcc cctatctctc
    14881 ctaataaaga caagggccta acagcatcta tggtcaacaa ttatgtgaaa aatggttacc
    14941 tgacaaagcc tgacaaaaaa aaataccaac gccaacagat tgcccgtttg attgctatca
    15001 caaccctcaa gtctgtattt tctattcaag aaatagccca gacacttaat actctacaaa
    15061 ctcaagcaag ttcagaccaa ctctacgatg cttttgtgga ctacatgaac caaggaattg
    15121 acccagctaa ccctattatc caaaccagct gccaaaccgt taaactctat catcaaactc
    15181 tagacttaat cgatcatact caagaggagg taatccaatg aacactagtc ttaaactcag
    15241 caaacaactc agttttggag aggagattgc taatagcgtg acccatgctg tgggtgcagt
    15301 catcatgctt atcttgctgc ctatttcatc catctatagt tatgaagcac acggattttt
    15361 atcctctatc ggcgtttcca ttttcgtcat cagtctcttt ctcatgttcc tatcatccac
    15421 catttatcac tctatggcct atggttcgac ccacaaatat gttttgcgaa tcattgacca
    15481 ttctatgatt tacgttgcca ttgccggctc atacacgccc gttgtcttga ccttgatgaa
    15541 taactggttt ggctatctga ttattgtcat ccaatgggga acgaccatct ttggtattct
    15601 ctataaaatc tttgctaaaa aggtcaatga gaaatttagc cttgctcttt acctgattat
    15661 gggctggttg gttctggcta tcattcctgc cattatcagt caaacgacac ccgttttctg
    15721 gagtctcatg gtaactggcg gactctgtta tacagttgga gctggatttt atgccaagaa
    15781 aaaaccttat ttccacatga tttggcatct ctttatccta actgcgtccg tacttcaata
    15841 catcgctatt gtttattaca tgtaaaaaag ttgagaaatt caatctcaac ttttttcttt
    15901 acacatattg ataaagtact ggtgcaagcg cacatcatca gtcaattctg gatgaaaaga
    15961 acttaccaac atattttttt cttgggctgc aacaatttga ttgttcactg ttgctagaat
    16021 ttctacaccc tcaccaacac tactgataat cggaccacgg ataaaggtca ttggaatctt
    16081 gccaactccc ttacattctg cttccgtgta gaaacttcct aattggcgcc cataagcatt
    16141 acgctcgacc accatatcca tagttcctag atgactctct ttctgagaag tgatttcctt
    16201 agccagcaaa attaagcccg cacaggtccc aaacactggt aagccagata gaatggcttc
    16261 tcggatggga agtagcatgt tctggtcacg taagagcttg cccatggttg tagactcacc
    16321 accaggcaaa atcaaacccg acaagtcact ctgatcttgc tgaaaatcat ctagatttct
    16381 gagttctaca ctctcgacac ctaattgatc tagcactttt gcatgttctg caaaggcccc
    16441 ttgcaaggcc aatattccga ttttcatcta ttttcctcgt tcagccatga gaatttggat
    16501 ttcattttca ttaataccaa ccatggcttc tcctaaatct tcagagattt gagctaggat
    16561 ttgaggatta cggaagttag tcacagcctt aacaatggca ctcgctcgtt taacaggatc
    16621 tcctgacttg aaaatacctg aaccgacaaa gaccccctct gcccctaatt gcatcattaa
    16681 cgcagcatct gctggcgttg caacacctcc agcagcgaaa tttacaactg gcaattttcc
    16741 atgttcatga acatattgga ccaattctac agggacttgc aaatccttgg cagcaacata
    16801 aagctcgtcc tcacgtaagt tttgaatgcg gcgaatttcc tgattcatca tacgcatatg
    16861 acgaacagct tggacgatat cccctgtccc tggttctcct ttggtacgaa tcatggaagc
    16921 accttcagcg atacgacgca aggcttcacc caaatcctta gcaccacaga caaaaggaac
    16981 ttggaattct ttcttgtcca catggaaacg gtcatcagct ggagatagaa cttcactctc
    17041 gtcgatataa tcaatttcaa tagcctctaa aatctgagct tcaacaaaat gcccgattct
    17101 gaccttagcc attactggaa tactaaccgc ttcttggatt tccttaatca tctttgggtc
    17161 gctcatgcgg gaaactcctc cagctgcacg aatatcagcc ggaattcgtt ccaaggccat
    17221 cacagctgcc gcaccagcag cttctgcgat acgagcctgt tcaggattct gcacatccat
    17281 aataacacca cccttgagca tctgtgccaa gtttttattt agttcataac gattttcagt
    17341 catttgtttt atcctcatca tttgtattgg tagctacctt ttcattttaa gtcagaacag
    17401 aatgaagcac aagataaaaa aactataatt gtatggggac agattggcta aaaactatct
    17461 gaccttaact taaggccaga tagctcattc atttttattt ttcagccgta agggcagcca
    17521 ttgtgatgta gttgtatggt ttattgaagt gtggcaagaa gaagaggtct gtcaatgcca
    17581 atttatcaat tgtcacatgc tcttggatag caagtgagaa catgtggatt cccatgctaa
    17641 ttgcaatatc atgtgaaacc atttgggcac caagaatttc acgactatct ttgtcaaaga
    17701 caatcttaat tgctacttca tggttgtcat gtttcatgaa ttctggtttt tgaagatcgt
    17761 taaagcctgt ttcagttgcg ttgtaaccag cagctttcgc tttttcaaga gtcaaaccag
    17821 ttgaaaccat gtgaagaccg tagattgaga taccatttga accttgaaca ccgattcctt
    17881 ccaattcatg tccacaagcg ttgtaggcac caacgatacc agtgcgaaca gcatttgaag
    17941 caagagcgat atagcttgta tctttacgag cattgtcata aacagtcgca cagtcaccaa
    18001 cagcgtaaac gcctgggata gatgtttctt gtttcttgtc tacaaggaag gcaccgttgc
    18061 ggaagagttc gatcttacca tcagcaaggg ctgtgtttgg acggaaacca actgcaagga
    18121 taaccatatc cacgtcaaag ctttctttgt cagtaatcaa gcgttcaact ttaccatcac
    18181 cttcgattgc tttaacagtt tgacctagag ccaagcggat gttgtgatct tccaagttct
    18241 tcgccatcat ttgtgtgaag tctttgtcat agtaaccgtt caagacagta tcaacgatat
    18301 caacaaggac aacttctttt ccaagacgtt caaaggcttc agcaagttca acaccgatgt
    18361 aaccaccacc aacaacggcg atacggtcga gatgttggct cttgtcagaa agtttattga
    18421 taacttcttc agcattttgg tacaatttca cgaattgtac gttttcaaga gttgctttaa
    18481 attcgcggtt tcctttaaca atttcaacac cttcgattgg tggcaagatt ggtgtagaac
    18541 ctgtagcgaa aatcaatttc tcgtatgatt ctttgtgttc ttttccttca acttctgctg
    18601 taaccacttt gttatcatag tcgattgaaa gaactggtga attcatataa accttagcac
    18661 ctttagcttc taatttgtct ttatcagaat agaacaagcc ttcagcaccg tcaatttgtt
    18721 caccaatcca aagagccatt ccacatccta ggaaagagat gttagagttt tggtcaaata
    18781 caacaatttc gttctcattt ccaaaattat ccaacatggt attgatacat gctgtaccag
    18841 cgtggttagc accgactaca acgattttac tcataaaaaa tttcctgcct tcattctaaa
    18901 tttactttac tagtatacca tttaccgtta gcgtttacaa gggggggact attatttcag
    18961 cattttttat caaaaataat tccccattta tcctgttttc aagcctcatg aattttatga
    19021 gcatatttct tgactttttc caaattttgt ttgtgaaaat tctaacttta tggtattata
    19081 ataacatgaa aataaaatgt aagggcttca atttagatga ttatttgata ttgcaactta
    19141 ttttctataa gagaaaggag ttggtagctt gactcttcgt tcacattctg aacggctaat
    19201 ggggactact atcactattt cattagtgga tgagcaagcc gatatctttc tccaaaaatc
    19261 ctttgacttg ctcaaagagc ttgaataccg cttcaacgcc aatagtcaag aatctgagtt
    19321 gatggaaatc aattatcaag caggaatatc ccccgtcaca gttcatccag acctgtttga
    19381 gctgatttca cttgggttag agcatagcct agcgctctct agccacctca atatcagcat
    19441 tggtccctta attcaaacct ggcgtatcgg tttttcagat gccaaggtcg cccagcctca
    19501 agaaattgaa tcggtgctgc ctctaatcaa tcctcatggt atcgagttag attcttctac
    19561 ttctactgtg tttttaaaac agaaaggaat gaagatcgat ctaggttgtt tagccaaagg
    19621 atacagtgcg gataaggttg cccaatttct taggaaagag ggggtgactt ctgccttgat
    19681 caatctggga gggaatatcc tgaccattgg aaaaaatcag gcaagagggg ataacccatg
    19741 gcaaatcggg attcaagacc cagccaatcc taggggaaat catttaatga ccatccctgt
    19801 tgtcaataaa tctgtcgtga cttcaggcat ttatgaacgt cacctgaccg tcgatggaca
    19861 agattaccat cacatttttg acagtcaaac aggatatcct gttgaaacgg aactagcgag
    19921 tctaacaatc atctctgata aatcagtcga tggcgaaatc tggacgactc gactctttgg
    19981 agaaagacct gcttctatcc tctggcaagt cgaaagtttg gagggcatcg aagtcatcct
    20041 catcgataaa gaaggccacc taagctgttc ttcaggaatt cctactctat agagacaact
    20101 gtttcaatgg aattttaaaa ttgtattatg taaaaagaga aaggaaatct catgttaaaa
    20161 cttattgcta ttgttggaac aaattcaaaa cgttctacaa accgtcaatt gcttcaatac
    20221 atgcaaaaac actttgctga caaagctgaa attgaacttg ttgaaatcaa gaccattcct
    20281 gtcttcaaca aaccagctga caagcaagta cctgctgaaa tattggaaat ttctgctaaa
    20341 atcgaagagg cagatggcgt tattatcggt actcctgagt atgatcactc tattccagct
    20401 gttttgatga gcgctcttgc ttggttgtct tatggtattt acccactttt gaacaaacca
    20461 atcatgatta caggtgcttc ttacggtacg cttggttcat ctcgtgccca attgcaactt
    20521 cgtcaaatct tgaatgctcc tgaaatcaag gcaaatgttc ttccagatga attcttgctc
    20581 tcacactctc ttcaagcatt taacccaagt ggcgacttgg ttgaccttga tgttatcaag
    20641 aaattggatg ccatctttga tgacttccgt atcttcgtga agattactga gaaattgcgc
    20701 aatgcgcaag aattgcttcg caaagatgct gaagactttg actgggaaaa tttgtaagat
    20761 aggagaccaa aaagaatgaa atttgttgga cttgttggat caaactacga tcaatcatat
    20821 aaccgtaagc tcttggaatt tatccgtcgc tacttcaaac tcaaatttga attagaagtt
    20881 cttgaaattg acgaagttcc aatgtttaac caagatgaaa aatgggatga aagtttccaa
    20941 ttacgttatt tatataacaa aattactcgt gcagatggtg ttatcattgc tactcctgag
    21001 cataaccaca ctatctcagc ttcactcaaa tctgtacttg aatggctttc atacgaagtt
    21061 catccatttg aaaacaagcc tgttatgatt gtgggtgcat catactatga ccaaggaaca
    21121 tcacgtgctc aagttcacct tcgtaaaatc cttgatgctc caggtgttaa tgcctacacg
    21181 cttccaggta acgaattcct tcttggtaaa gctaaggaag cttttgataa caacggaaat
    21241 atcaccaacg aaggcactgt taaattcctt gaaacttgct tagataactt tgttaaatac
    21301 gtaggagtcg tttcgaaatt gaaaaaacca aaaccaatcg aatcagaaga cttggattgt
    21361 ggaaaaccaa tcgctacaac catcacagaa gttgaccctg acgatccaga atgggtagaa
    21421 aaagttgcag caatcactgg tgctgtttct ggtgatacct atgtcaaatt ggaccacggt
    21481 atcctaacag ttaaccaaat tgatatgttc ttgaaagcta tgccatttga attgacatac
    21541 gctgacgaca acaaccaatt cctctactac aacaacgctc accaagatcc agacactatg
    21601 ttcgctaaac gtgtaccacc tcaatcaggt agccgtatgt cgactgttca tggttctctt
    21661 ccaccagcac gtatgaagaa cgtagagtgg gttatcggaa cacttcgcaa cggaaaccaa
    21721 gaatacgtcc gtacgatcgt tccaggttct cctgcaggtg ttatcaacac tcacaactac
    21781 caagcaatgt actatcctga tggatcatac gctggtatca atgaaatcgt ctttaacttc
    21841 caaccatggc ttgactggta cctaaaagag actggtcaac gtttggtggg tggtagcgga
    21901 ccatttgctc ctgctgccgg aggtcatgga gacgccgatg ctacttctgg cgcttctgat
    21961 tcaggggatg ctggaggcca cggtggtgac gcagacgcta cagccggtgc aagttactaa
    22021 tgatagtttt taggaaccat tatggttcct tttttagcga aaaaagacta gcaaacacaa
    22081 actgctagtc tctttgttat cgtttcatct atctttgtta aaagaaagag tacatattat
    22141 gaatttgggt catcaagact acggccatgt aatccttttt cacgttgtac ttggcgtagt
    22201 ttttctggtg taacatcgtt tccttcttcg tccacaattt tgattccttc aatgtggtga
    22261 cgaacagcgc ggcgataacc ttcgatgtac tcctcacgta gtttggcttg ttccactttt
    22321 tcttctggtg ttaagccttc tgtttttttc tttttagcaa gctcattgat acgagcaatt
    22381 tttttcggat ccatttcttc tcctttgtaa taagataaag tccgtttatc aaattttatt
    22441 tagtgttaat ttggttaaaa caagcaaact tagctgcttt cttggttagt tgtgacaaga
    22501 ttgccaaacg attttgacgg acagcctgat cttcagccat taccatagta ttttcaaaga
    22561 aagcatcaat gactgggcta agcgcaaaga gttgtttcaa ttgctgactt gcaggtcctg
    22621 ataaaacgag tgtttctact gcttctgcca aagctttttc ttggtcattc tcaaatagtt
    22681 ctgaatcaac tgtagcaacc ccttctgcct tctcagccag gttaaaggca cgagaaagtg
    22741 attcaacaga tggtttaaaa tcttcttcct tgcttacttc tacgagagca cttgctgctt
    22801 ccaacatatc tgccacaaca aagtttgaac ctgcaagaac tgcttccttg atatcttttg
    22861 gagtagagcc catcatctta tcaacacgag ccttgataaa gtccataacc tctgctttat
    22921 tttcataagt caaactgtca aatttcaatg cataaaggct atcaatcagc tcatccatag
    22981 caatgtgcca accaaaggca tccaagatac gaaccacacc ttgagttgca cgacgaaggg
    23041 cataagggtc attagaacct gatggaatca atcctactga gaagaaactc aaaatcgtat
    23101 ccaatttgtc tgcaatggct agaactgcgc cgaccttgct ctctggaagt tctccttcag
    23161 ctgatgtagg catgtagtgt tcacgaatag cagctgccac cgctggagtt tcaccagcaa
    23221 gaagggtgta tttttcaccc ataattcctt ggagttcgtc aaattcacca accatacctg
    23281 tcaacaagtc aaacttgtaa atggctgctg cacgagcaag gtcaactgtt tcatccactg
    23341 acaaaccagc tttttctgcc aaaagtacag tgatttgacc cgtacgaatc atgtgttcac
    23401 gaagggaacc aatcttctca tggaaggtga cattgtttaa tttttcaaca agatctgaaa
    23461 tcaccaattt ttggtcttca cgccagaaga attctccgtc ttccaagcgg gctactaaga
    23521 ctttttcatt tcctttgatg acatttttca aacgctctgc gtttccgtta cgaacagaaa
    23581 tgaagtttgg caagagtttt ccatcttgat cacgaacaac aaagtaacgc tggtgttcct
    23641 tcatagaagt caccaagact tcttctggaa cttcaaggta tttagcatca aaacttccca
    23701 tgaaggcagt tgggtattca accaaattca agacttcatt cagcaaatcc gcatcaattt
    23761 cgatacgtac accatgtttt gcctcaattt ccttgatttg gtcaacaatc atttgctcac
    23821 gttcacatgg atctgcgatt acaaactgct tacgaaggtc ttcttcatag ctcaatgctg
    23881 actgaatttt ggtttctttc cccaagaaac gatggccacg gctcacacga cttcccttga
    23941 tatcaaggaa atccaagtca aactcttgct catccaagag aacagttaaa gtgtgaacag
    24001 ggcggatgta ttcaaagcta tttccagccc agtgcatgct gacagggaaa gtcaatgact
    24061 tcaagacatc tacaacacca ggaacaatgg cttcaactga ttggccaact tcttccttag
    24121 tgacatagac atattcttca cccttaattt cacggaattc gatatcttca acagtcaaac
    24181 ctttcccacg gacaaatcct tgagctgctt tggtgaagtt tccatcacta tccaaggcaa
    24241 ttttctttgc tggtcccttg aaatcttctg tcaaatcaga ctgtttgtct gataaaccag
    24301 tcacacgaac agccaaacga cgtggtgttg agaaggtttg aatggcttca aaagacaggc
    24361 ggttttcctt gaggaaggct gccatttttt cgcctagttg tttttcactt ggtgtgacaa
    24421 cataggctgg taattcttca agaccgagtt ctactaataa gttttttgtc atgttttttc
    24481 tccgaaaagt atctttttat tttccagttt gccttatgtg attggcacgc aagcaaccaa
    24541 cttcgttgtt tcattgctaa aattggagcc aaaagtctcc aattttgcct agtatcctta
    24601 gtttcactaa ggataccttc atcactgcgg caactggctc agggctcact ctgttcgccc
    24661 attttcgtaa tttgtcactc tctttattct gcgtcttctg ctaggagttt agctcttgtt
    24721 tcttcatcca aaagtgggta gcctaggcgt ttgcgttctg cgacaaaggt tttggctacg
    24781 acacgggcca agttacggat acgagcgata tagcctgcac gctctgttac agatacggca
    24841 ccacgcgcgt caagcagatt aaaggtatgt gaacatttga gaacatagtc ataggcaggg
    24901 tgtaccaagc cttcttctaa tgcacgacca gcttcttttt caaacttatc aaagttttca
    24961 agcaacattt cttggtccga aatttcaaat gaatattttg agtgctcata ctcaggctgg
    25021 ataaagattt ctccgtattt tacaccatca gcccactcga tatcatagac agagtctact
    25081 tcttgaatgt aagaagccaa gcgctccaaa ccataggtaa cttccgcagt cacagggcca
    25141 gttgccaatc caccgacttg ttggaaataa gtgaactgag tgatttccat tccgtcaagc
    25201 caaacttccc aaccaagacc agctgaacca gttgatgggt tttcccagtt gtcctcaaca
    25261 aaacgaatat cgtgctccaa aggattgatt cccaattttt ccaaagattc aaggtaaagt
    25321 tcttggatat ttgatggaga aggcttcatg accacctgga attggtggtg ttggtagaga
    25381 cggttagggt tttccccata acgaccgtca gcaggacgac gtgatggctc tacataagct
    25441 gcattccatg gctcaggtcc gatagcacga aggaaagtgt aaggactcat tgttcccgca
    25501 cctttttcat tatcataagc ctgcataagc atacaacctt ggtcattcca aaattgttgc
    25561 aaagtaagga tgatttcctg gaaagtcaat ttcttagaca ttgtttactc ctttttatat
    25621 aaattacttg cgacatgagt ctgcctcgtc gatcatacga ggcaagacga gttagtactg
    25681 cgtctagctc aggcactcta gtgctgagcg tggggcagtc cgactgtaag gaggtttctg
    25741 ccactgacgc agtgaaatgt caatttctta gacattgttt actcctttag tttttatatt
    25801 tctttttcaa ttaatttctg ctgaacaaac caatctaaca agggaaaagt tttttctgta
    25861 tttgcccata aatgataaga atctaagacc gcttgtacac tacctaaatt ttctaccaac
    25921 ttatctactg tcaaaaagct gcgccagtat tcataaaaaa tacttgcata gttcttatca
    25981 taagtcgaag aaccaaaatc attcaatgaa tgccaaccat acttcttctg aaaaagttct
    26041 acgagagatt gattacaaat tttttccgct tgaaattcct cttctgtcaa gaaatacttg
    26101 cgactaatat attcaaccat cccctcttcg aaccagatat aagagtcata accatcaaaa
    26161 tcatctaaaa aatgctccga ccaatgagct aactcatgtc ctacaatctg taagaggaaa
    26221 ttttcagata aagaatgata gtgactttct attgcttgag tttgctgaga acactcgtag
    26281 tccatcaatt gatacaaata caactctttc caaacagcta aatcaggcgc cataaccatt
    26341 cgtctattat ttgtataggc tggaacagcg ctttccctaa taatctgtgt agcagcatta
    26401 aaatctgacc aaataacggc ttgcggtaaa tcacagactg caagttcatt ctttaaaaaa
    26461 gattgataat ctttcaactt ttcagtattt cttactacaa aatcacgaaa tgtagctagt
    26521 tgactatcgt cttttacaag ataaaggttg tccacggctc tcctttcttt cacacaatag
    26581 actgaataag caaaagaacc gcgtccgaca atcctaggtt gatttaacct aggggcgtca
    26641 gaaacgcggt tccaccctaa tttattactt cattgttttt gaaaatacta cagaaagcgc
    26701 cagctcatta ttttgcccta cttggctccc actatcccaa gctcgcttga agaacgccat
    26761 aagactttct ttcctgctga ctattatatc aaaaattaga ataatgtaca attcttttta
    26821 tgattttcta gaaatccaca tcatcaactc gtggagcacc cgattgaaca gcaatcgttt
    26881 ttaagttttc tctctcctca tgactcagtt caattccaaa gcaatcaaga ttagcttgaa
    26941 tacgagaggt tgtgacagat tttggaagtg gtaaaaatcc ttctgccaag ctccaggcca
    27001 aggctatctg agcaatcgat tttccgtgat ttgctgcgat ttcttgcact tgcttgctat
    27061 caaatagttc tccctgacca aaaggccccc aagcttccaa taaaattccc ttttcacgac
    27121 agtaagctac gacttgatct tgatacacac ctggcgccaa gcgaacttga ttgaccgcag
    27181 gaacgatagt tgcagtttca agcaaggcat ccaaatgatg gggaagaaaa ttgctaacgc
    27241 cgatagcacg gattttccct tcttgataga ggtcttccat cgctctccaa acttccgcat
    27301 tgcgagtttt ccatgcgtca ttttctctga gcggttttgg gttcggccaa tgaatcaaat
    27361 acaaatccaa ataatccaag cccagttttt ctatagattt ttccaaagct tgacgagttt
    27421 gctcataggt ttgctgacta ttccaaagct tggtagttac gaacatttct tcacgtggaa
    27481 ctccgctatc tttgattgct tgaccaacac tttcttcatt ctgataaatc gccgccgtat
    27541 caatatgacg ataaccagcc ttcaaggctt ctaacactgc acgataggct tcttctccat
    27601 ccttagcctt aaaagttcca aatcccaata ctggaatttc tactccatta tttaattgat
    27661 aggtattcat atgcttctcc ttctatttta ttcatcaatt atagcataaa acatttttta
    27721 agtagtacta tcttctgtaa aaaataagtc tgtcaaatat ctaacagacc tattttttct
    27781 tgcttattca tcacgactat agtacagctc atgagctttt aggcgagtat tgagcatctc
    27841 tggtatggtc acaaaggtat aaccttgatt tttcaaatac tcaatgaccc ttggcaaggc
    27901 attgactgtc ggactgtgaa tatcatgcat caaaacgata gagccgttag ctacttgatg
    27961 ctgaatttct gtcaaaatag atgcttcatt tttactcttc cagtccagac tatccacatc
    28021 ccacatgata aagctcaaat ccaagctatt gcgaatatca tctgtaatag caccataagg
    28081 tggacgcatg agtttagaac tagaacccag cactttagtt agcacatcct cagtatcagt
    28141 aatctgcttt ttagcttcat caagagagag ttgcgagaga atcggatggc tccaactatg
    28201 gtttccaaca acatgacctt cagattttat cctcttcacc aagtcctcat tcccagaaac
    28261 atttttccca agcacaaaga aagtcgcttt aatatcatat ttagctaggg tctctaatac
    28321 ctgcggggtc gttgctggat ttggaccatc atcaaaggtt agagcgacaa ctttttgata
    28381 tttcttatca aagtaagatt ggtacaaggc cgcatctttt tcgagtaagt acgaagattg
    28441 gataacatca aagaaagcag atactggcaa ggctatctct tctaaatttt caaccacagg
    28501 acttggataa aggataatct gactatcctt gtaatcaaaa ttccatgcag acaagtcttg
    28561 gtcagagaag ttttttacaa tctgctcact ctggtcttgc tctatttttt tatcctctat
    28621 gaaggaggtc aactctttta tcagctgttc cttagcctta ctagcatctg aaaacagttg
    28681 gtcaagtgta aaaggttggc catcttctgt taagtgaacc tttcctagac tggtcttttc
    28741 agtctcttca accttaaaag caactaaatc atagatttgt ttggtcacat tacgattaac
    28801 gactcccttt aaacctgact cttcttgctc tgtatagtag aaaacaagat tgtccttact
    28861 ttctagcttg tccttaacat cttgatttat caactcccta acagaggaaa tcactttctc
    28921 cccttggaga ggataatagg caatcacttc ggcttgcccc tgacgaaaat gctccttctg
    28981 atttccctca ctcaattgat catctttctc ttttttgagc gattcaatct tttgctcaaa
    29041 acttttttgc tggtagatct taaaagcaat aaatccgcct aataggcaaa tagaaattgc
    29101 taaaatacca atcaaagcca ataatacatg tctcgttttc ccgtgtctgc cacgtcctag
    29161 tctactttta ttcatattta tatcataaca aatttgagca ataatttcaa tgatacaatt
    29221 tggcaatcca caattcctct agcaagccaa agcatcttac atcaactcca acatccgtat
    29281 ctgtagagat tatgtagttt tctatctatg gaatttctag tagattgaag ctagaatagt
    29341 agacctatac ttctaaaaca ttgttagaaa tcgatttgac tgtcctgatc gatttgtcct
    29401 gttctcattt cattttacta taaaactatg aaaagctagg tcatctgaga agtaattact
    29461 atcgacaatt gcgatagcgt atactggtgc gatgtgtttg tagctctggt gggtatcacc
    29521 ttcacgttgg caaatttttt ctaggttttg attaacctga ctgcacagat aagcccatag
    29581 gcgattgatg aaaaaattct gatgatgaac ctgaatttcg atgataactt ggattccatt
    29641 atctaactcc gccaagacgt ctatactagt atagaaatcc tgcgctgagt agggcatgga
    29701 aggcaagacg tgaatgttac ttccctccaa aatcgtcaca ttttttgctg gcaagtccag
    29761 catatcgcgg ataaattgac aaatcattag ttgggctgat acccggatgt ctgagaatcc
    29821 tccttttcct ccttctatta tagcacattt ttaaatctag gtttgctaga ttctatgctt
    29881 ctatctattt attcggaaaa gaaagctttt cttcagaaga aagctaatag cttatttgaa
    29941 attttctcct ctctgttgga tagtcccgtc tatctatgtt ataatgaaag aaggatttaa
    30001 aatcggaaaa ggagtattta tgctaaaatt aggtgtcatc ggaactggcg ctatcagcca
    30061 tcatttcata gaagcatccc ataccagtgg agaataccaa ctggtcgcaa tctattctag
    30121 aaaactagaa actgcagcaa cctttgcttc tcgctatcaa aatatccaac tattcgatca
    30181 attagaagtc ttcttcaaat cttcttttga tttagtctat atcgccagtc caaactcctt
    30241 acattttgct caggcaaaag ctgccttgtc tgctggtaaa catgttattc ttgaaaagcc
    30301 agctgtcact caaccacaag aatggtttga tttgattcaa acagctgaaa aaaataactg
    30361 ttttatcttt gaagcagctc gtaattatca cgagaaagcc tttactacta tcaaaaactt
    30421 tttagcagat aagcaagtgt taggagcaga tttcaactat gccaaatact cttccaagat
    30481 gcctgacttg ttggctggac aaacaccaaa tgtcttttca gaccgttttg ctggtggagc
    30541 cctcatggat ttggggattt atcccctcta tgctgctgtt cgtctttttg gaaaagccaa
    30601 tgacgcgact taccatgctc aacagcttga caatagcatt gacctaaatg gagatggtat
    30661 cctcttctac ccagactatc aagttcacat caaggctgga aaaaacatca cttccaatct
    30721 tccttgcgag atttatacaa cagatggaac cttgactctc aacacgattg agcatattcg
    30781 ctcagctatt tttaccgacc accaaggaaa tcaagtccag cttcctatcc aacaggctcc
    30841 tcatacgatg actgaggaag tcgctgcatt tgcacacatg atccagcaac cagatctgaa
    30901 tctctaccaa acttggctgt atgatgcagg ctctgttcat gagctactat ataccatgcg
    30961 ccagactgct ggcattagat ttgaggcaga aaaatgaaaa ccaaactacc gactgaatgg
    31021 caagaactga gtgaccaact cggtttccaa gaattcaccc ccattcaaac tcaactattt
    31081 gagccccttc ttgctggaga aaacctccta ggagtgagca aaaccggaac tggtaagacc
    31141 ctagcgtatc tcctaccaag tcttctcaga ctacaaaaga aaaaagccca acaactcttg
    31201 attctagcac caaatacaga acttgctgga cagatttttg atgtatgtaa aacgtgggca
    31261 gaagctatcg gattgactgc tcaactcttc ctttcaggtt caagtcagaa acgacaaatt
    31321 gaacgtctta aaaaggggcc agaaattctg attggaactc ctggccgtat ctttgaactc
    31381 attaaactta aaaaaatcaa gatgatgaat gtggaaacca tcatcctgga tgaatttgac
    31441 caattactag atgattctca gattcacttt gtagaaaaaa tcactcacta cgcacctcgt
    31501 gaccaccaac tgatctacat gagtgccacg accaagtttg accaagaaaa gattgtgccg
    31561 aatacacgca ctattgatct ctctgatcaa aaattggaca atatccagca tttctacatg
    31621 caggtagacc aacgtcatcg agtggatatg ctacgaaaac tggctcatgt agaggatttc
    31681 cgtggtctag tcttcttcaa tagcctgtca gaccttggga atgccgagga aaaactacag
    31741 tatcgtgata tattggctgt ttccctcgct agtgatgtta atgttaaatt tagaaaagtc
    31801 atcttagaaa agtttaaaga taaccaacta accctgcttc ttgcaactga ccttttggct
    31861 cgtggaattg atatcgatag cctagaatgt gtcgtaaact ttgatattcc tagagatagc
    31921 gaaacctaca cacaccgtgc tggccgtact ggccgtatgg gcaaggaagg atatgttatt
    31981 actctcgtca ctcatccaga agaaatcaaa aaacttaaaa agtttgcaag tatccgagaa
    32041 attgtcctaa aaaaccaaga actctatatc aaataaagcc ccattgctct atacacatcc
    32101 agtgtatgga gcttttttat aagcaattca attttatact catctgcttt caaaaagcat
    32161 tctagtccat ctccgattaa cgatggactt tatcacctcc ttctccagtc cttgtatgac
    32221 atcttggagt tgattcatga catcttccaa agttcgaaag gctttattct taaatccacg
    32281 tttacgaatc tctttccaca cttgttcaat ggggttcatc tctggtgtgt acggaggaat
    32341 aaatgcaaag ccaatattag tcggaatctt taaggtactt gatttatgcc atatagcatt
    32401 gtctataacg agtaaaaaat aatcatatgg ataagcttgt gaaagctctt ctaaaaagac
    32461 gttcatccac tcagtattac atccaccagc tattaagaaa actgatgcgc ctgtatgggc
    32521 atcaa
//
LOCUS       DAVLXH010000019        31907 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00028199
            SAMN33607166-rid17955573.denovo.019, whole genome shotgun sequence.
ACCESSION   DAVLXH010000019 DAVLXH010000000
VERSION     DAVLXH010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607166
            Sequence Read Archive: SRR23725544
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 31907)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31907)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721421.1
            Genome Coverage       :: 115x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:42:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,210
            CDSs (total)                      :: 2,161
            Genes (coding)                    :: 2,023
            CDSs (with protein)               :: 2,023
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 73 of 138
            Pseudo Genes (incomplete)         :: 60 of 138
            Pseudo Genes (internal stop)      :: 40 of 138
            Pseudo Genes (multiple problems)  :: 31 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31907
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607166-rid17955573.denovo.019"
                     /strain="AUSMDU00028199"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1349"
     gene            complement(191..328)
                     /locus_tag="VYO11_001001"
                     /pseudo
     CDS             complement(191..328)
                     /locus_tag="VYO11_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
     gene            complement(706..1395)
                     /gene="rplA"
                     /locus_tag="VYO11_001002"
     CDS             complement(706..1395)
                     /gene="rplA"
                     /locus_tag="VYO11_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HEV1595589.1"
                     /translation="MAKKSKQLRAALEKIDSTKAYSVEEAVALAKETNFAKFDATVEV
                     AYNLNIDVKKADQQIRGAMVLPNGTGKTSRVLVFARGAKAEEAKAAGADFVGEDDLVA
                     KINDGWLDFDVVIATPDMMALVGRLGRVLGPRNLMPNPKTGTVTMDVAKAVEESKGGK
                     ITYRADRAGNVQAIIGKVSFEAEKLVENFKAFNETIQKAKPATAKGTYVTNLTITTTQ
                     GVGIKVDVNSL"
     gene            complement(1603..2028)
                     /gene="rplK"
                     /locus_tag="VYO11_001003"
     CDS             complement(1603..2028)
                     /gene="rplK"
                     /locus_tag="VYO11_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004226069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HEV1595590.1"
                     /translation="MAKKVEKLVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGMIIPVVISVYEDKSFTFITKTPPAAVLLKKAAGVEKGSGTPNKTKVASVTR
                     AQVQEIAETKMPDLNAANLESAMRMIEGTARSMGFTVVD"
     gene            complement(2151..2867)
                     /locus_tag="VYO11_001004"
     CDS             complement(2151..2867)
                     /locus_tag="VYO11_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HEV1595591.1"
                     /translation="MKKRYVILSGLLALTLAACSQEKTKVEENTQKTEQSSQPEGTVG
                     SKSQASSQKKAEVSNKGSYYSIQGKYDEIILANKRYPLSKDYNPGENPTAKAELLKLI
                     AAMQAEGYPISDQYSGFRSYETQAKLYQDYVNQDGKEAADRYSARPGYSEHQTGLAFD
                     LIGTDGDLVTEEKAAQWLLDHAADYGFVVRYLKGKEKETGYMAEEWHLRYVGKEAKEI
                     AASGLSLEEYYGFEGGDYVD"
     gene            complement(2885..3346)
                     /locus_tag="VYO11_001005"
     CDS             complement(2885..3346)
                     /locus_tag="VYO11_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000335612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HEV1595592.1"
                     /translation="MCLICQRIELIKAGQNPYFVKELETGYVVIGDHQYFKGYTLFLA
                     KDHVTELHHMETSVKLRFLEEMSLVQEAVAKAFEAEKMNIELLGNGDAHAHWHLFPRR
                     AGDMKSHGLNGRGPVWWVPWEEMAAEDCQVQSPELEEMIKILSHELEKYLA"
     gene            complement(3348..4385)
                     /locus_tag="VYO11_001006"
     CDS             complement(3348..4385)
                     /locus_tag="VYO11_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HEV1595593.1"
                     /translation="MNQTVEYIKELTAIASPTGFTREISNYLVKTLEGFGYQPVRTAK
                     GGVNVTIKGQKNEEHRYVTAHVDTLGAIVRAVKPDGRLKLDRIGGFPWNMIEGENCTV
                     HVTSTGKTVSGTILIHQTSCHVYKDAGTAERTQDNMEVRLDEKVTNEKETRALGIEVG
                     DFISFDPRTVVTETGFIKSRHLDDKVSAAILLNLLRVYKEEGIDLPMTTHFAFSVFEE
                     VGHGANSNIPEEVVEYLAVDMGAMGDDQQTDEYTVSICVKDASGPYHYDFRQHLVALA
                     KEQDIPFKLDIYPFYGSDASAAMSAGAEVKHALLGAGIESSHSYERTHIDSVVATERM
                     VDAYLKSEAVS"
     gene            complement(4483..5808)
                     /gene="brnQ"
                     /locus_tag="VYO11_001007"
     CDS             complement(4483..5808)
                     /gene="brnQ"
                     /locus_tag="VYO11_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006152071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HEV1595594.1"
                     /translation="MAKKGTLTGLLLFGIFFGAGNLIFPPSLGALSGEHFLPAIAGFV
                     FSGVGIAVLTLIIGTLNPKGYIYEISTKIAPWFATLYLSVLYLSIGPFFATPRTATTA
                     YEVGISPLLSDANKGLGLIVFTVLYFAAAYLISLNPSKILDRIGRILTPVFAILIVIL
                     VVLGAIKYGGTSPQAASAAYQASAFGTGFLEGYNTLDALASVAFSVIAVQTLKQLGFS
                     SKKEYISTIWVVGIVVALAFSALYIGLGFLGNHFPVPAEAMKGGTPGVYILSQATQEI
                     FGSTAQLFLAAMVTVTCFTTTVGLIVSTAEFFNERFPQISYKVYATAFTLIGFAIANL
                     GLDAIIKYSIPVLVILYPITIAIVMIVIVNKFVALSKPGMQLTIAVVTVIAIASVLGS
                     SFKVEFLANLVSVLPFAKASLPWLVPAIVGILLSLVLPNKQESDVFEME"
     gene            complement(5980..6072)
                     /locus_tag="VYO11_001008"
     CDS             complement(5980..6072)
                     /locus_tag="VYO11_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEV1595595.1"
                     /translation="MRSARACQFLLEQGYNVINVQGGMLAFEEL"
     gene            complement(6115..6267)
                     /locus_tag="VYO11_001009"
     CDS             complement(6115..6267)
                     /locus_tag="VYO11_001009"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEV1595596.1"
                     /translation="MKEIAFDAFYQLYQNDQLSLVDVREVDEFAALHLEGAHNLPLSQ
                     LADSYD"
     gene            complement(6427..7005)
                     /locus_tag="VYO11_001010"
     CDS             complement(6427..7005)
                     /locus_tag="VYO11_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase family protein"
                     /protein_id="HEV1595597.1"
                     /translation="MSQIERIKQAIMADSQNASYTERGIEPLFAAPKTARINIIGQAP
                     GLKTQEAGLYWKDKSGDRLRDWLGVDEDTFYNSGYFAVLPMDFYFPGHGKSGDLPPRT
                     GFAEKWHPQLLQELPDIQLTLLIGQYAQAYYLQEKISGKVTERVKHYKDYLPAYFPLV
                     HPSPRNQIWMAKNPWFEAEVVPDLKKRIKTIL"
     gene            complement(7059..8459)
                     /gene="pepV"
                     /locus_tag="VYO11_001011"
     CDS             complement(7059..8459)
                     /gene="pepV"
                     /locus_tag="VYO11_001011"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HEV1595598.1"
                     /translation="MIAIDFTAEVEKRKEDLLADLFSLLEINSERDDSKADAQHPFGP
                     GPVKALEKFLEIADRDGYPTKNVDNYAGHFEFGDGEEVLGIFAHMDVVPAGSGWDTDP
                     YTPTIKDGRLYARGASDDKGPTTACYYGLKIIKELGLPTSKKVRFIVGTDEESGWADM
                     DYYFEHVGLAKPDFGFSPDAEFPIINGEKGNITEYLHFAGENTGAARLHSFTGGLREN
                     MVPESATAVVSGDLTDLQAKLDAFVAEHKLRGELQEEAGQYKVTIIGKSAHGAMPASG
                     VNGATYLALFLSQFGFAGPAKDYLDIAGKILLNDHEGENLKIAHVDEKMGALSMNAGV
                     FRFDETSADNTIALNIRYPKGTSPEQIKSILENLPVASVSLSEHGHTPHYVPMEDPLV
                     QTLLNVYEKQTGLQGHEQVIGGGTFGRLLERGVAYGAMFPDSIDTMHQANEFIALDDL
                     FRAAAIYAEAIYELIK"
     gene            complement(8472..9077)
                     /locus_tag="VYO11_001012"
     CDS             complement(8472..9077)
                     /locus_tag="VYO11_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002924506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HEV1595599.1"
                     /translation="MKFLELNKKRHATKHFTDKPVDPKDVRTAIEIATLAPSAHNSQP
                     WKFVVVREKNAELAKLAYGSNFEQVSSAPVTIALFTDTDLAKRARKIARVGGANNFSE
                     EQLQYFMKNLPAEFARYNEQQVSDYLALNAGLVAMNLVLALTDQGIGSNIILGFDKSK
                     VNEVLEIEDRFRPELLITVGYTDDKLEPSYRLPVDEIIEKR"
     gene            9248..10048
                     /locus_tag="VYO11_001013"
     CDS             9248..10048
                     /locus_tag="VYO11_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV1595600.1"
                     /translation="MKKFSLLLAILPFLVACGNQATPKETSAQKTIVLATAGDVPPFD
                     YEDKGNLTGFDIEVLKAVDEKLSDYEIQFQRTAWESIFPGLDSGHYQAAANNLSYTKE
                     RAEKYLYSLPISNNPLVLVSNKKNPLTSLDQIAGKTTQEDTGTSNAQFINNWNQKHTD
                     NPATINFSGEDIGKRILDLANGEFDFLVFDKVSVQKIIKDRGLDLSVVDLPSADSPSN
                     YIIFSSDQKEFKEQFDKALKELYQDGTLEKLSNTYLGGSYLPDQSQLQ"
     gene            complement(10230..11063)
                     /locus_tag="VYO11_001014"
     CDS             complement(10230..11063)
                     /locus_tag="VYO11_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001015777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HEV1595601.1"
                     /translation="MNHKIAILSDIHGNATALEAVIADAKTQGASEYWLMGDIFLPGP
                     GANDLVALLKELPITASVRGNWDDCVLEALDGQYGLEDPQEVQLLRMTQYLMERMDPA
                     TIVWRRSLPLLEKKEIDGLRFSISHNLPDKNYGGDLLVENDTEKFDQLLDAETDVAVY
                     GHVHKQLLRYGSQGQQIINPGSIGMPYFNWEALKNHRAQYAVIEVEDGELVNIQFRKV
                     AYDYEAELELAKSKGLPFIEMYEELRREDNYQGHNLELLASLIEKHGYVEDVKDYFDF
                     L"
     gene            complement(11053..12900)
                     /gene="uvrC"
                     /locus_tag="VYO11_001015"
     CDS             complement(11053..12900)
                     /gene="uvrC"
                     /locus_tag="VYO11_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HEV1595602.1"
                     /translation="MNNLIKSKLELLPTSPGCYIHKDKNGTIIYVGKAKNLRNRVRSY
                     FRGSHDTKTEALVSEIVDFEFIVTESNIEALLLEINLIKENKPKYNIMLKDDKSYPFI
                     KITNERYPRLIITRQVKKDGGLYFGPYPDVGAANEIKRLLDRIFPFRKCTNPPSKVCF
                     YYHIGQCMAHTICKKDETYFKSMAQEVSDFLKGQDNKIIDELKGKMAAAAQTMEFERA
                     AEYRDLIQAIGTLRTKQRVMAKDLQNRDVFGYYVDKGWMCVQVFFVRQGKLIERDVNL
                     FPYFNDPDEDFLTYVGQFYQEKSHLVPNEVLIPQDIDEEAVKALVDTKILKPQRGEKK
                     QLVNLAIKNARVSLEQKFNLLEKSVEKTQGAIENLGRLLQIPTPVRIESFDNSNIMGT
                     SPVSAMVVFVNGKPSKKDYRKYKIKTVVGPDDYASMREVIRRRYGRVQREALTPPDLI
                     VIDGGQGQVNIAKQVIQEELGLDIPIAGLQKNDKHQTHELLFGDPLEVVDLSRNSQEF
                     FLLQRIQDEVHRFAITFHRQLRSKNSFSSQLDGIDGLGPKRKQNLMRHFKSLTKIKEA
                     SVDEIVEVGVPRAVAEAVQTKLNPQETEILLQVAEERVDYQTEGNHNKP"
     gene            complement(12940..13641)
                     /locus_tag="VYO11_001016"
     CDS             complement(12940..13641)
                     /locus_tag="VYO11_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="matrixin family metalloprotease"
                     /protein_id="HEV1595603.1"
                     /translation="MRWLFRLIGAFFSFVWRLFWRLVWIVVLLCVLAFGLLWYLNGDF
                     QGALKQAERSVKIGQQSIDQWEKTGQLPKLSQTDSHQHSEGRWAQASARIYLDPQMDS
                     RFQEAYLEAIQNWNQTGAFNFELVTESSKADITATEMNDGGTPVAGEAESQTNLLTGQ
                     FLSVTVRLNHYYLSNPYYGYSYERLVHTAEHELGHAIGLDHTDEKSVMQPAGSFYGIQ
                     EEDVANLRKIYETSE"
     gene            complement(13720..14952)
                     /gene="murN"
                     /locus_tag="VYO11_001017"
     CDS             complement(13720..14952)
                     /gene="murN"
                     /locus_tag="VYO11_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurN"
                     /protein_id="HEV1595604.1"
                     /translation="MALTTLTKEEFQTYSDQVSSRSFMQSVQMGDLLEKRGARIVYLA
                     LKQEGEIQVAALVYSLPMLGGLHMELNSGPIYTQQDALPVFYAELKEYAKQNGVLELL
                     VKPYETYQTFDSQGNPIDAEKKSIIQGLTDLGYQFDGLTTGYPGGEPDWLYYKDLTEL
                     TEKSLLKSFSKKGKPLVKKAETFGIRLKKLKREELSIFKNITKETSERREYSDKSLEY
                     YEHFYDTFGEQAEFLIASLNFSEYMSKLQGEQSKLEENLDKLRLDLSKNPHSEKKQNQ
                     LREYSSQFETFEVRKAEARDLIEKYGEEDIVLAGSLFVYMPQETTYLFSGSYTEFNKF
                     YAPALLQKYVMLESIKRGIPKYNFLGIQGIFDGSDGVLRFKQNFNGYIVRKAGTFRYH
                     PSPLKYKAIQLLKKIVGR"
     gene            complement(14957..16177)
                     /gene="murM"
                     /locus_tag="VYO11_001018"
     CDS             complement(14957..16177)
                     /gene="murM"
                     /locus_tag="VYO11_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurM"
                     /protein_id="HEV1595605.1"
                     /translation="MYRYQIGIPTLEYDQFVKEHELANVLQSSAWEEVKSNWQHEKFG
                     VYREEKLLATASILIRTLPLGYKMFYIPRGPILDYGDKELLNFAIQSIKSYARSKRAV
                     FVTFDPSICLSQSLINQEKTEFPENLAIIDSLQQMGVRWSGKTEEMGDTIQPRIQAKI
                     YKENFEEDKLSKSTKQAIRTARNKGLEIQYGGLELLDSFSELMKKTEKRKEIHLRNEA
                     YYKKLLDNFKDKAYITLATLDVSKRSQELEEQLAKNRALEETFTESTRTSKVEAQKKE
                     KERLLEELTFLQEYIDVGQARVPLAATLSLEFGTTSVNIYAGMDDDFKRYNAPILTWY
                     ETARYAFERGMVWQNLGGVENSLNGGLYHFKEKFNPTIEEYLGEFTMPTHPLYPLLRL
                     ALDFRKTLRKKHRK"
     gene            complement(16289..17068)
                     /locus_tag="VYO11_001019"
     CDS             complement(16289..17068)
                     /locus_tag="VYO11_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HEV1595606.1"
                     /translation="MAVMKIEYYSQVLDMEWGMNVLYPDANRVEEPECEDIPVLYLLH
                     GMSGNHNSWLKRTNVERLLRGTNLIVVMPNTSNGWYTDTQYGFDYYTALAEELPQVLK
                     RFFPNMTSKREKTFIAGLSMGGYGCFKLALATNRFSHAASFSGALSFQNFSPESQNLG
                     SPAYWRGVFGEIRDWTTSPYSLESLAKKSDKKTKLWAWCGEQDFLYEANNLAVKNLKK
                     LGFDVTYSHSAGTHEWYYWEKQLEVFLTTLPIDFKLEERLT"
     gene            complement(17137..18798)
                     /locus_tag="VYO11_001020"
     CDS             complement(17137..18798)
                     /locus_tag="VYO11_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HEV1595607.1"
                     /translation="MSNISLTTLGGVRENGKNMYIAEIGESIFVLNVGLKYPENEQLG
                     VDVVIPNMDYLFENSDRIAGVFLTHGHADAIGALPYLLAEAKVPVFGSELTIELAKLF
                     VKGNDAVKKFNDFHVIDENTEIDFGGTVVSFFPTTYSVPESLGIVLKTSEGSIVYTGD
                     FKFDQTASESYATDFARLAEIGRDGVLALLSDSANADSNIQVASESEVRDEITQTIAD
                     WEGRIIVAAVSSNLSRIQQIFDAADKTGRRIVLTGFDIENIVRTAIRLKKLSLANEIL
                     LIKPKDMSRFEDHELIILETGRMGEPINGLRKMSIGRHRYVEIKDGDLVYIATAPSIA
                     KEAFVARVENMIYQAGGVVKLITQSLHVSGHGNVRDLQLMINLLQPKYLFPVQGEYRE
                     LDAHAKAAMAVGMLPERIFIPKKGTTMAYENGDFVPAGSVSAGDILIDGNAIGDVGNV
                     VLRDRKVLSEDGIFIVAITVNRREKKIVARARVHTRGFVYLKKSRDILRESSELINQT
                     VEDYLQGDDFDWADLKGKVRDNLTKYLFDQTKRRPAILPVVMEAK"
     gene            complement(18973..21195)
                     /gene="recJ"
                     /locus_tag="VYO11_001021"
     CDS             complement(18973..21195)
                     /gene="recJ"
                     /locus_tag="VYO11_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001832038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HEV1595608.1"
                     /translation="MITPTYEWQFALQVEDADFTKIAKKAGLGPEVARLLFERGIQDQ
                     ESLKKFLEPSLEDLHDAYLLHDMDKAVERIRQAIEEGENILVYGDYDADGMTSASIVK
                     ESLEQLGAECRVYLPNRFTDGYGPNASVYKYFIEQEGISLIVTVDNGVAGHEAIALAQ
                     SMGVDVIVTDHHSMPETLPDAYAIVHPEHPDADYPFKYLAGCGVAFKLACALLEEVQV
                     ELLDLVAIGTIADMVSLTDENRILVQYGLEMLGHTQRIGLQEMLDMAGIGANEVTEET
                     VGFQIAPRLNALGRLDDPNPAIDLLTGFDDEEAHEIALMIHQKNEERKEIVQSIYEEA
                     KTMVDPEKKVQVLAKEGWNPGVLGIVAGRLLEELGQTVIVLNIEDGRAKGSARSVEAV
                     DIFEALDPHRDLFIAFGGHAGAAGMTLEVEQLSDLSQVLEDYVREKGADAGGKNKLNL
                     DEELDLEALSLETVKSFERLAPFGMDNQKPIFYIKNFQVESARTMGAGNAHLKLKISK
                     GEASFEVVAFGQGRWATEFSQTKNLELAVKLSVNQWNGQTALQLMMVDARVEGVQLFN
                     IRGKNAVLPEGVPVLDFPGELPNLAASEAVVVKNIPEDITQLKTIFQEQHFSAVYFKN
                     DIDKAYYLTGYGTRDQFAKLYKTIYRFPEFDIRYKLKDLAAYLNIQQILLVKMIQVFE
                     ELGFVTIKDGVMTVNKEAPKREIGESQIYQNLKQTVKDQEMMALGTVQEIYDFLMEKE
                     "
     gene            21472..22230
                     /locus_tag="VYO11_001022"
     CDS             21472..22230
                     /locus_tag="VYO11_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV1595609.1"
                     /translation="MALVEFKNVEKYYGDYHALRNINLRFEKGQVVVLLGPSGSGKST
                     LIRTINGLEAVDKGSLLVNGHQVAGASQKDLVPLRKEVGMVFQHFNLYTHKTVLENVT
                     LAPIKVLGIDKKEAEKTAQKYLEFVNMWDKKDSYPAMLSGGQKQRIAIARGLAMHPEL
                     LLFDEPTSALDPETIGDVLAVMQKLAHDGMNMIIVTHEMGFAREVADRIIFMADGEVL
                     VDTTDVDNFFDNPSEARAQQFLSKIINHESDKVK"
     gene            22270..23034
                     /locus_tag="VYO11_001023"
     CDS             22270..23034
                     /locus_tag="VYO11_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000624332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEV1595610.1"
                     /translation="MISLFGLAAAKPVQADTSIADIQKRGELVVGVKQDVPNFGYKDP
                     KTGTYSGIETDLAKMVADELKVKIRYVPVTAQTRGPLLDNEQVDMDIATFTITDERKK
                     LYNFTSPYYTDASGFLVNKSAKIKKIEDLNGKTIGVAQGSITQRLITELGKKKGLKFK
                     FVELGSYPELITSLHAHRIDTFSVDRSILSGYTSKRTALLDDSFKPSDYGIVTKKSNT
                     ELNDYLDTLVTKWSKDGSLQKLYDRYKLKPSSHTAD"
     gene            23047..23436
                     /locus_tag="VYO11_001024"
     CDS             23047..23436
                     /locus_tag="VYO11_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000131131.1"
                     /note="The N-terminal region of this protein, as described
                     by TIGR01726, is a three transmembrane segment that
                     identifies a subfamily of ABC transporter permease
                     subunits, which specificities that include histidine,
                     arginine, glutamine, glutamate, L-cystine (sic), the
                     opines (in Agrobacterium) octopine and nopaline, etc;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HEV1595611.1"
                     /translation="MTDLSSWTAYFQDFGQFFNGFLFTLALAIGSFILAMVLGVFFGA
                     MSTSKRPILRILARIFVEFYQNTPLLVQFVIVFYGLPLISDHTIMIPIYWTAVLCVGL
                     YHGAYIAEVIRSGIQSLHPDCPHLLQL"
     gene            23641..24831
                     /locus_tag="VYO11_001025"
     CDS             23641..24831
                     /locus_tag="VYO11_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferric reductase-like transmembrane
                     domain-containing protein"
                     /protein_id="HEV1595612.1"
                     /translation="MKSVKGLLFIIASFILTLLTWMNTSPQFMIPGLALTSLSLTFIL
                     ATRLPLLESWFHGLEKVYTVHKFTAFLSIILLIFHNFSMGGLWGSRLAAQFGNLAIYI
                     FAGIILVAYLGKYIQYEAWRWIHRLVYLAYILGLFHIYMIMGNRLLTFNLLSFLVGSY
                     ALLGLLAGFYIIFLYQKISFPYLGKITHLKRLNHDTREIQIHLSRPFNYQSGQFAFLK
                     IFQEGFESAPHPFSISGGHGQTLYFTVKNSGDHTKNIYDNLQAGSKVTLDRAYGHMII
                     EEGRENQVWIAGGIGITPFISYIREHPILDKRVHFYYSFRGEENAVYLDLLRDYAQKN
                     PNFELHLIDSTKDGYLNFEQKEVPEHATVYMCGPISMMKALAKQIKKQNPKTELIYEG
                     FKFK"
     gene            complement(25152..26033)
                     /locus_tag="VYO11_001026"
     CDS             complement(25152..26033)
                     /locus_tag="VYO11_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HEV1595613.1"
                     /translation="MAIVSAEKFVQAARDNGYAVGGFNTNNLEWTQAILRAAEAKKAP
                     VLIQTSMGAAKYMGGYKVARNLIANLVESMGITVPVAIHLDHGHYEDALECIEVGYTS
                     IMFDGSHLPVEENLKLAKEVVEKAHAKGISVEAEVGTIGGEEDGIIGKGELAPIEDAK
                     AMVETGIDFLAAGIGNIHGPYPVNWEGLDLDHLQKLTEALPGFPIVLHGGSGIPDEQI
                     QAAIKLGVAKVNVNTECQIAFANATRKFARDYEANEAEYDKKKLFDPRKFLADGVKAI
                     QASVEERIDVFGSEGKA"
     gene            complement(26174..27502)
                     /gene="vncS"
                     /locus_tag="VYO11_001027"
     CDS             complement(26174..27502)
                     /gene="vncS"
                     /locus_tag="VYO11_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase VncS"
                     /protein_id="HEV1595614.1"
                     /translation="MKRTGLFAKIFIYTFSIFSVLVICLHLAIYFLFPSTYLSHRQET
                     IGQKATAIAQSLEGKDRQSIEQVLDLYSQTSDIKGTVKGEMTEDKLEVKDSLPLDTDR
                     QTTSLFIEEREVKTQDGGTMILQFLASMDLQKEAEQISLQFLPYTLLASFLISLLVAY
                     IYARTIVAPILEIKRVTRRMMDLDSQVRLRVDSKDEIGNLKEQINSLYQHLLTVIADL
                     HEKNEAILQLEKMKVEFLRGASHELKTPLASLKILIENMRENIGRYKDRDQYLGVALG
                     IVDELNHHVLQILSLSSVQELRDDRETIDLLQMTQNLVKDYALLAKERELQIDNSLTH
                     QQAYLNPSVMKLILSNLISNAIKHSVPGGLVRIGEREGELFIENSCSSEEQEKLAQSF
                     SDNASRKVKGSGMGLFVVKSLLEHEKLAYRFEMEENRLTFFIDFPKVAQD"
     gene            complement(27499..28155)
                     /gene="vncR"
                     /locus_tag="VYO11_001028"
     CDS             complement(27499..28155)
                     /gene="vncR"
                     /locus_tag="VYO11_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor VncR"
                     /protein_id="HEV1595615.1"
                     /translation="MKILIVEDEEMIREGVSDYLTDCGYETIEAADGQEALEQFSSYE
                     VALVLLDIQMPKLNGLEVLAEIRKTSQVPVLMLTAFQDEEYKMSAFASLADGYLEKPF
                     SLSLLKVRVDAIFKRYYDTGRIFSYKDTKVDFESYSASLAGQEVPINAKELEILDYLV
                     KNEGRALTRSQIIDAVWKATDEVPFDRVIDVYIKELRKKLDLDCILTVRNVGYKLERK
                     "
     gene            complement(28204..28287)
                     /gene="pep27"
                     /locus_tag="VYO11_001029"
     CDS             complement(28204..28287)
                     /gene="pep27"
                     /locus_tag="VYO11_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_198523890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative autolysis signal peptide Pep27"
                     /protein_id="HEV1595616.1"
                     /translation="MRKEFHNVLSSDQLLTDKRPARDYNRK"
     gene            complement(28467..29846)
                     /gene="vex3"
                     /locus_tag="VYO11_001030"
     CDS             complement(28467..29846)
                     /gene="vex3"
                     /locus_tag="VYO11_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit Vex3"
                     /protein_id="HEV1595617.1"
                     /translation="MLHNAFAYVTRKFFKSIVIFLIILLMASLSLVGLSIKGATAKAS
                     QETFKNITNSFSMQINRRVNQGTPRGAGNIKGEDIKKITENKAIESYVKRINAIGDLT
                     GYDLIETPETKKNLTADRAKRFGSSLMITGVNDSSKEDKFVSGSYKLVEGEHLTNDDK
                     DKILLHKDLAAKHGWKVGDKVKLDSNIYDADNEKGAKETVEVTIKGLFDGHNKSAVTY
                     SQELYENTAITDIHTAAKLYGYTEDTAIYGDATFFVTADKNLDDVMKELNGISGINWK
                     SYTLVKSSSNYPALEQSISGMYKMANLLFWGSLSFSVLLLALLLSLWINARRKEVGIL
                     LSIGLKQASILGQFITESILIAIPALVSAYFLANYTARAIGNTVLANVTSGVAKQASK
                     AAQASNLGGGAEVDGFSKTLSSLDISIQTSDFIIIFVLALVLVVLVMALASSNLLRKQ
                     PKELLLDGE"
     gene            complement(29898..30545)
                     /gene="vex2"
                     /locus_tag="VYO11_001031"
     CDS             complement(29898..30545)
                     /gene="vex2"
                     /locus_tag="VYO11_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding subunit Vex2"
                     /protein_id="HEV1595618.1"
                     /translation="MTLLQLQDVTYRYKNTAEAVLYQINYNFEPGKFYSIIGESGAGK
                     STLLSLLAGLDSPVEGSILFQGEDIRKKGYSYHRMHHISLVFQNYNLIDYLSPLENIR
                     LVNKKASKNTLLELGLDESQIKRNVLQLSGGQQQRVAIARSLVSEAPVILADEPTGNL
                     DPKTAGDIVELLKSLAQKTGKCVIVVTHSKEVAQASDITLELKDKKLTETRNTSK"
     gene            complement(30558..31835)
                     /locus_tag="VYO11_001032"
     CDS             complement(30558..31835)
                     /locus_tag="VYO11_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1595619.1"
                     /translation="MNPIQRSWAYVSRKRLRSFILFLILLVLLAGISACLTLMKSNKT
                     VESNLYKSLNTSFSIKKIENGQTFKLSDLASVSKIKGLENVSPELETVAKLKDKEAVT
                     GEQSVERDDLSAADNNLVSLTALEDSSKDVTFTSSAFNLKEGRHLQKGDSKKILIHEE
                     LAKKNGLSLHDKIGLDAGQSESGKGQTVEFEIIGIFSGKKQEKFTGLSSDFSENQVFT
                     DYESSQTLLGNSEAQVSAARFYVENPKEMDGLMKQVENLALENQGYQVEKENKAFEQI
                     KDSVATFQTFLTIFLYGMLIAGAGALILVLSLWLRERVYEVGILLALGKGKSSIFLQF
                     CLEVVLVSLGALLPAFVAGNGITTYLLQTLLASGDQVSLQDTLAKASSLSTSILSFAE
                     SYVFLVLLSCLSVALCFLFLFRKSPKEILSSIS"
BASE COUNT         9041 a         7267 c         5975 g         9624 t
ORIGIN      
        1 aaccatacgc acggcaaggc gacgttgacg tggtttgaag agattttcga agagtattag
       61 aaagctcgat ggactattcc agattcattc cactagattt cgaaatcgag taggagataa
      121 tctctagccc ctctcacacc accgtacgtg ccgttcggca tacggcggtt caactaactg
      181 ttaacgcatg tcattcaagg taataatcca aacacgaaac cagtccacgt ttttcaagga
      241 ctggttttga tatagcacgt ttaagtaccg acttctgagc tactaattga tagtggtcgc
      301 cccagccaga taccttatcc gctatatagg ccttattatc acgttcctgt tcgtagagcc
      361 acgatttcgc tatcccttcc tctgacgatt cttatttcca gcgtcagact taaaacggtc
      421 tatccccaga ccgttttaat ccgctacctc acgatagtca gacttgggaa tcgctattgg
      481 gttcaccggt agcaggtgcc caccgaggac ttacacctca aatatataat aaaatgaaat
      541 aagaatagga cgaatcgatc aggacagtca aatcaatttc taacaatgtt ttagaagtag
      601 atgtgtacta ttctagtttc aatctactat acaacatgcc cgtcgtacat caaaaaaagt
      661 tgagacatag cgtcttcaac ttttttacat tactttaact actgattaaa gtgagtttac
      721 gtcaactttg ataccaacac cttgagtagt tgtgatagtc aagtttgtta cgtaagttcc
      781 tttagctgta gctggttttg ctttttggat tgtttcgttg aaagctttaa agttttcaac
      841 caatttttca gcttcaaatg atactttacc gatgattgct tgaacgttac ctgcacggtc
      901 agcacggtaa gtgattttac cacctttaga ctcttcaact gctttagcaa catccattgt
      961 tacagtacca gttttagggt ttggcatcaa gttacgtggt ccaaggacac gtccaagacg
     1021 tccaacaaga gccatcatat caggtgtagc gataactacg tcgaagtcca accaaccgtc
     1081 gttgatttta gcaacaaggt catcttcacc aacaaagtct gcaccagcag cttttgcttc
     1141 ttcagctttt gcaccacgtg cgaaaacaag aacacgtgaa gttttaccag taccgtttgg
     1201 caataccatt gctccacgga tttgttggtc agctttttta acgtcgatgt tcaagttgta
     1261 agcaacttct acagttgcat caaattttgc aaagttagtt tcttttgcaa gtgctacagc
     1321 ttcttctaca ctgtatgctt ttgtgctgtc gattttctca agagcagcac gaagttgttt
     1381 gcttttttta gccattttct attctccttg taagtggttc aatcgatttt catctcccac
     1441 gtcacttctc gaaatgatga agtcttgcgg gttttcagtc tactattttt ctcttcctac
     1501 ggccttaagc tcccttgctg tacccaagta caagcctcag tcacttgcct agtatgaaaa
     1561 gcaactaata gactgctgtg agattttcta ctgtgttatt gattagtcaa caacagtgaa
     1621 tcccatagaa cgagcagtac cttcgatcat acgcattgca gactcaaggt ttgcagcgtt
     1681 caaatctggc atcttagttt ctgcaatttc ttgtacttgc gcacgagtaa ctgaagcaac
     1741 tttagttttg ttaggtgtac ctgatccttt ttcaacacct gcagcttttt tcaaaagaac
     1801 agcagctggt ggtgtcttag tgatgaaagt aaatgattta tcttcgtaaa ctgagataac
     1861 aactggaatg atcataccag cttgatcagc tgtacgagcg ttgaactctt ttgtgaatcc
     1921 catgatgttg ataccagctt gaccaagagc aggtccaacc ggtggagctg gtgtagcttt
     1981 accagcaggg atttgcaatt ttacaagttt ttcgactttt ttagccattt ctaaatcctc
     2041 ctttgtggtt ttggcggtaa tgtaagattt ttacctccca caagtatgct ttacacatac
     2101 ctttccatta tacactattt atctaaaaat gcaagagaaa actttcattt ttaatcgaca
     2161 taatcgccgc cttcaaagcc atagtactct tccaaactga gaccacttgc agcaatttct
     2221 ttggcttctt ttccaacgta gcggagatgc cattcttctg ccatgtagcc agtctccttt
     2281 tccttgcctt taagatagcg aacaacaaag ccatagtcag ccgcatggtc caagagccac
     2341 tgggctgcct tttcttcagt aactaaatcc ccatctgtcc caatcaaatc aaaagcaaga
     2401 cccgtctggt gttcactgta acctgggcgt gctgagtagc gatctgctgc ttccttacca
     2461 tcttgattga catagtcttg gtagagctta gcctgagttt cataactcct aaacccactg
     2521 tattggtcac tgattggata gccctcagcc tgcatagctg cgattagttt gagcaactct
     2581 gccttggctg ttggattttc tcctggattg taatcttttg acaaaggata acgtttatta
     2641 gctaggataa tctcatcgta tttcccttgg atactataat agctcccttt attgctaact
     2701 tctgcctttt tctgactaga agcttgagat ttgctaccta cagttccttc cggttgactg
     2761 ctttgctccg ttttttgagt gttttcttca actttggttt tttcttgcga acaagctgca
     2821 agggtcaatg ctagtaaacc agataaaatg acatatcttt ttttcatttc tttcttcctc
     2881 tctcttaggc caaatacttc tccaattcat gagataagat tttaatcatc tcttccagct
     2941 ctggcgattg tacttggcaa tcttctgccg ccatttcttc ccagggcacc caccagactg
     3001 ggccacggcc attcaaaccg tgactcttca tatcacctgc tcttcgggga aaaagatgcc
     3061 aatgagcgtg ggcatcgcca tttcctagga gttcaatatt catcttttca gcctcaaatg
     3121 ctttggcgac tgcttcttgg actaaactca tttcctctaa aaagcgaagt tttacagaag
     3181 tttccatatg atggagttct gtgacatgat cttttgctaa aaataaggta tagcccttaa
     3241 agtattggtg gtcaccaata acaacatagc ctgtttctag ttcttttaca aagtagggat
     3301 tttgcccagc tttaatgagt tcgattctct gacagattaa gcacattcta tgataccgcc
     3361 tcgctcttaa gataagcatc aaccatacgc tcagtcgcta ctactgaatc gatgtgggtg
     3421 cgctcataag agtgactgga ctcaatacca gctccaagaa gtgcatgctt gacctctgca
     3481 cctgctgaca tcgctgctga agcgtccgat ccgtaaaatg gatagatgtc gagcttaaat
     3541 ggaatatctt gctctttcgc caaagctact aagtgttgac ggaagtcata gtgataagga
     3601 ccggaagcat cctttacaca gatagatact gtgtactcat ccgtctgttg gtcatcgccc
     3661 atagctccca tatccacagc cagatattct actacctctt ctggaatatt ggagttagca
     3721 ccatggccca cctcttcaaa gactgaaaaa gcaaagtgtg tcgtcatcgg caagtcaatt
     3781 ccttcttctt tataaactcg aaggagattt agcaaaattg ctgcgctgac cttgtcgtcc
     3841 aaatgtcgag acttgataaa accagtctct gtcacgacag ttcgcgggtc aaagctgatg
     3901 aagtcaccaa cctcaatacc caaggcacgt gtttcttttt cattggtcac tttttcgtct
     3961 aaacgaactt ccatattgtc ctgagtgcgt tcagcagttc ctgcatcttt gtagacatgg
     4021 caagaagtct ggtggatgag gatagttcca gataccgttt tacctgtact agtcacatga
     4081 acggtacagt tttcaccctc aatcatgttc caaggaaaac caccgatccg gtccaatttg
     4141 agacgaccgt caggtttgac agcacgaaca atggctccga gtgtgtccac atgggcagtt
     4201 acatagcgat gttcttcgtt tttttgacct ttgatggtca cattgacacc acccttggct
     4261 gtgcgaactg gctggtaacc aaaaccttct agagtcttga ctaaataatt cgaaatttca
     4321 cgagtgaagc ccgttggcga tgcgatggct gtcagttctt tgatatattc tactgtttga
     4381 ttcatttctt cacctctttc gctacctatt ataacacatt tatcatcgga taaaaaaaga
     4441 aaatcactcc tgtagacttg gctacaaaag tgatttaagt gattattcca tttcaaaaac
     4501 atcgctttct tgcttgtttg gtagaaccaa tgagagcaag attccaacaa tggctggcac
     4561 caaccatggg agagatgcct tggcaaaagg aagaacgcta acaagatttg caagaaactc
     4621 aaccttaaac gagcttccta gtacgcttgc aatggcaata actgtaacca cagcaattgt
     4681 caactgcata cctggttttg aaagggcaac aaatttgttg acaatgacaa tcataacgat
     4741 agcaatcgtg attgggtaca agataaccag tactggaatt gagtacttga taatcgcatc
     4801 aagacccaaa ttggcaatag caaatccaat caaggtaaag gctgtcgcat aaaccttgta
     4861 gctgatttgt gggaagcgct cattaaagaa ctcagctgtt gacacaatca aaccaacagt
     4921 cgttgtgaag caggttacgg taaccatagc tgcaaggaag agttgagctg ttgagccaaa
     4981 gatttcttga gtggcttgtg acaagatgta aacacctggt gttccaccct tcatcgcttc
     5041 agctggtact gggaaatgat ttccaagaaa acctaaaccg atgtaaagag cgctgaaggc
     5101 aagggcaaca acgataccaa caacccaaat agttgaaatg tattctttct tacttgaaaa
     5161 tccaagttgt ttcaaggttt gaactgcgat tacgctaaag gccactgagg caagggcgtc
     5221 caaggtattg taaccttcta ggaaacctgt accaaaggca gaagcttgat aagcagctga
     5281 agcagcttga ggacttgttc caccatattt gatagctccc agaacgacca agataacaat
     5341 caaaattgca aagactggcg ttaaaatacg tccaatgcgg tctaagattt ttgatggatt
     5401 aagcgaaatc aaataggctg ccgcaaaata cagaaccgta aatacaatca agccaagtcc
     5461 tttatttgca tccgacaaaa gggggctaat ccctacttcg taagctgttg tagcagtacg
     5521 tggggtagca aagaatggac cgattgacaa gtaaagaact gagaggtaaa gagtcgcaaa
     5581 ccaaggcgct atcttcgttg aaatctcgta gatatatcct ttaggattta gcgttccaat
     5641 aataagggtc aagacggcga taccaacgcc tgaaaagaca aaacctgcga tggcaggaag
     5701 aaaatgttct ccagatagag cacctagaga aggcggaaaa atcaagttcc ccgcaccaaa
     5761 aaatattcca aacaggagca aacctgttag ggtacctttt ttagccataa aaatctcctt
     5821 catatttata aaatactgac ctagtatacc acgattagga gtctgaaaaa agcatcacga
     5881 ggcaaatatt aaatgttttc aattttctta aaaataagaa ttatctaaaa ataaaaactc
     5941 tcctacccag tccacaccaa gtaggagaaa tgcaaaattt taaagttctt caaaggctaa
     6001 catgccaccc tggacattga taacattata accttgttct aacaggaatt ggcaagcacg
     6061 cgccgatctc attccagatt tgcaaataat ataatgcaag cgatctttgt ccaattaatc
     6121 ataactatca gccaattgac taagcggtag gttgtgggca ccttctaaat gaagagctgc
     6181 aaactcatcc acttctctca catccactag agaaagctgg tcgttttggt aaagctggta
     6241 aaatgcgtca aaggctattt ctttcattct ttttcttcta atactcttcg aaaatctctt
     6301 caaaccacgt cagcgtcgcc ttaccgtgcg tatgttaccg acttcgtcag ttttatctgc
     6361 aacctcaaag ctgtactttg agcagcctac gactagcttc ctagtttgct ctttgatttt
     6421 cattgactat aaaatggttt taattctttt tttcaaatct ggcactactt ctgcctcaaa
     6481 ccaaggattt ttggccatcc agatttgatt tcgtggtgat gggtgaacta gcggaaaata
     6541 ggctggcaga tagtctttat agtgtttcac cctctccgtt accttcccac tgattttctc
     6601 ctgtaaatag taggcttggg catattgccc aatcaagagg gttaactgaa tatcaggcaa
     6661 ttcctgtaag agctgcggat gccatttttc tgcaaaacct gtacgaggcg gaagatcacc
     6721 cgacttgcca tgtcctggaa agtagaaatc cataggcaaa acagcaaaat aacctgaatt
     6781 gtaaaaggta tcttcatcca cacctagcca gtcccgcaag cggtcaccac ttttatcttt
     6841 ccagtaaagg cctgcttctt gagttttaag tcccggagcc tgaccgatga tattgatgcg
     6901 agcagttttt ggcgctgcaa agagaggctc aatgccacgc tctgtatagc tggcattctg
     6961 tgaatccgcc atgatagcct gtttgattct ttcgatttga gacatctact ttccctccaa
     7021 aaagaagtcc aagcataaga tctcagactt ctatcgtttt atttgatcaa ttcgtaaata
     7081 gcttcggcat aaattgctgc tgctcggaag agatcgtcca aggcaataaa ttcattggct
     7141 tggtgcatgg tatcaattga gtctgggaac atagcaccat aggcaactcc gcgctctaac
     7201 aagcgaccaa aggttccacc accgatgact tgttcatgac cttgtaggcc tgtttgtttt
     7261 tcatagacat tcaacaaggt ttgcacaagt ggatcttcca ttggcacata gtgaggggta
     7321 tgaccatgtt ctgatagact gacagaagca actggcaagt tttctaggat tgacttgatt
     7381 tgttctggac ttgttccttt tggatagcgg atgttaaggg caatggtatt atcagcactt
     7441 gtttcatcga agcggaagac gccggcattc atagaaagag cacccatctt ttcatccaca
     7501 tgagcaatct tgagattttc accctcatga tcgttcaaga gaattttacc tgcgatgtca
     7561 aggtagtctt tggctggacc agcaaagcca aactggctga ggaagagggc aaggtaagtt
     7621 gcgccattga cacctgaagc aggcatagca ccgtgggctg atttaccaat gatcgtcacc
     7681 ttgtattggc cagcttcttc ttggagttct cctctaagtt tgtgttctgc aacaaaggca
     7741 tctagtttag cttgcaagtc tgtcaagtca cctgaaacga ctgctgttgc tgattctggt
     7801 accatatttt cacgtaaacc acctgtaaag ctgtgaagac gggctgcacc tgtattttca
     7861 cctgcaaagt ggaggtattc cgtgatgttt cctttttcac cattgatgat tggaaattca
     7921 gcatctggtg agaaaccaaa gtctggcttg gcgagtccta cgtgctcgaa gtagtagtcc
     7981 atatctgccc agcctgattc ttcgtctgtt ccaacgatga agcgaacttt cttagaagtt
     8041 ggaaggccca attctttgat gattttcaaa ccatagtagc aagctgttgt aggtcccttg
     8101 tcatctgaag caccacgcgc ataaaggcga ccatctttga tagttggtgt gtaagggtct
     8161 gtgtcccaac cgctaccagc tggaaccacg tccatatggg caaagattcc gagaacttct
     8221 tctccatcac caaactcaaa atgtcctgca tagttatcaa catttttagt tggataacca
     8281 tcacggtctg cgatttcaag gaatttttcc aaggctttta ctggaccagg tccaaatgga
     8341 tgttgggcat cagccttgct atcatcacgt tctgagttga tttccaaaag gctaaacaag
     8401 tcagccaaga ggtcttcttt gcgtttttct acttctgctg taaaatcaat tgctatcatt
     8461 ttttcttctt cctatctttt ttcgatgatt tcatctactg gcaagcggta gcttggttcc
     8521 aatttgtcgt ctgtgtaacc cactgtgatc aagagttctg ggcggaaacg gtcttcaatt
     8581 tccaaaacct cattgacttt tgatttgtca aaaccaagga taatattgga accaattcct
     8641 tggtctgtaa gagcgagaac caagttcata gcaaccaaac ctgcattgag tgctaggtag
     8701 tcgctgactt gttgttcatt gtagcgtgca aattcagctg gcaaattttt catgaagtat
     8761 tgaagttgtt cttctgagaa attgttagca ccaccaactc gggcaatctt acgagcgcgt
     8821 ttggcaaggt ctgtatctgt aaatagggca atggttacag gtgctgatga tacctgctca
     8881 aagtttgaac cataagccaa ctttgccagt tcagcatttt tctcacgaac aactacaaat
     8941 ttccaaggct ggctgttgtg ggcgcttggc gccaaggttg caatttcgat agccgtacgc
     9001 acatcttttg gatcaacagg cttatcagtg aaatgcttgg tcgcatgacg ttttttattt
     9061 aattcaagaa atttcataat cgatttcctt ttctaattct actgcttcca ttctaccata
     9121 atttgaaaga gcttgcaggg atttttcatg attaagtttt tctatcacag acataaaaga
     9181 tatatattgg tttatcagga aagtttctga taaactagca agtactttac atttgaatgg
     9241 agacagtatg aaaaaattta gcctattact agctatccta ccatttttgg ttgcctgtgg
     9301 gaatcaagct acacccaaag agactagcgc tcaaaagaca atcgtccttg ctacagctgg
     9361 cgacgtgcca ccatttgact acgaagataa aggcaatctg acaggcttcg atatcgaagt
     9421 tctaaaggca gtagatgaaa aactcagcga ctacgagatt caatttcaaa gaaccgcctg
     9481 ggaaagtatc ttcccaggac ttgattctgg tcactatcag gctgcggcca ataacttgag
     9541 ttacacaaaa gagcgtgctg aaaaatacct ttactcgctt ccaatttcca acaatcccct
     9601 cgtccttgtc agcaacaaga aaaatccttt gacttctctt gaccagatcg ctggtaaaac
     9661 aacacaagag gataccggaa cttctaacgc tcaattcatc aataactgga atcagaaaca
     9721 cactgataat cccgctacaa ttaatttttc tggtgaggat attggtaaac gaatcctaga
     9781 ccttgctaac ggagagtttg atttcctagt ttttgacaag gtatccgttc aaaagattat
     9841 caaggaccgt ggtttagacc tctcagtcgt tgatttacct tctgcagata gccccagcaa
     9901 ttatatcatt ttctcaagcg accaaaaaga gtttaaagag caatttgata aagcgctcaa
     9961 agaactctat caagacggaa cccttgaaaa actcagcaat acctatctag gtggttctta
    10021 cctcccagat caatctcagt tacaataaca ctcttcgaaa atctcttcaa accacgtcag
    10081 ctttatctgc aacctcaaag ctgtgctttg agcaacctgc ggctagcttc ctagtttgct
    10141 ctttgatttt cattgagtat aagatatact aaaagcgatt ggaccagcca atcgcttttt
    10201 tagtttgcat tggttatttt aggaaacttt tacaaaaaat caaaataatc tttcacatcc
    10261 tctacatacc catgcttttc tattaagctg gctaaaagtt ccagattgtg tccctgatag
    10321 ttatcttcac gacgtagttc ttcatacatt tcgataaagg gaagcccctt ggacttggcc
    10381 aattctaact cagcctcgta atcataagca actttacgaa attggatatt gaccaattcc
    10441 ccgtcttcaa cttctatcac ggcatactgg gcacggtgat tttttaacgc ctcccaatta
    10501 aaatagggca tgccaatcga ccctggattg atgatttgtt gcccttgact accataacga
    10561 agcaactgct tgtgaacatg accataaact gccacgtccg tttccgcatc tagtagttgg
    10621 tcaaatttct ctgtatcatt ctcaactagc aagtcaccac catagttttt gtcaggtaaa
    10681 ttatgagaga tagaaaagcg caatccgtca atttctttct tttccagcaa aggcaagctt
    10741 cgtcgccaga caatcgttgc aggatccatt cgctccatca aatactgtgt catacgcaag
    10801 agctgaactt cctgtgggtc ttctaagcca tattgcccat ctaaagcctc aaggacacaa
    10861 tcatcccaat tgcctcgaac acttgccgtg ataggaagtt cctttaacag agcgaccaag
    10921 tcatttgcac ctggaccagg gaggaaaatg tctcccatga gccaatattc actggctcct
    10981 tgagttttag catctgcaat cactgcttct agcgccgtcg cattgccatg aatatctgat
    11041 aaaattgcga ttttatggtt tattgtggtt tccttccgtt tggtaatcta ctctttcttc
    11101 cgccacttga agcaagattt ctgtttcctg cgggttcaac ttggtttgca cagcctctgc
    11161 tactgctctt ggtactccaa cttcgacaat ctcatccaca ctggcttcct tgattttggt
    11221 cagagactta aagtgcctca tgagattttg cttgcgttta ggtcccagac catcaatccc
    11281 atccaattga gatgagaaag aatttttgga gcgcagttgg cggtggaagg taatggcaaa
    11341 gcggtggacc tcatcttgga tgcgttggag gaggaaaaat tcctgagaat tgcgagacaa
    11401 gtccaccact tccagcggat ctccaaagag caattcatgg gtttggtgct tatcattctt
    11461 ttgcagacct gcaattggaa tatccaagcc cagttcttct tggatgactt gcttagcaat
    11521 attgacttga ccttgccccc catcaatcac aatcaaatct ggaggagtca aagcctcacg
    11581 ctgtactcga ccatagcgtc tgcgaatgac ctctctcatg ctggcatagt cgtctggtcc
    11641 aacaaccgtt tttatcttgt acttacggta atccttctta ctcggtttac cgttgacaaa
    11701 gaccaccatg gctgaaacag ggctagttcc catgatatta gagttatcga aggactcgat
    11761 acgtactggg gtcgggattt ggagcaaacg tcctagattt tcaatagctc cttgggtctt
    11821 ctcgacagat ttctctagca ggttaaattt ctgctccaga ctaacacgtg cattttttat
    11881 ggctagattg accagctgtt ttttctctcc acgttggggt ttgagaatct tggtatccac
    11941 caaagccttg acagcttctt cgtcaatatc ctgcggaatc agtacctcat tgggaactag
    12001 gtgagatttt tcttgataga attgtcctac ataggtcaaa aaatcctcat ctggatcatt
    12061 gaagtagggg aagagattga catcgcgctc gatgagctta ccctgacgga caaagaaaac
    12121 ctgcacacac atccagccct tatccacata gtagccaaag acatcgcgat tttggagatc
    12181 cttagccatg acccgttgct tggttcgaag cgttccaata gcctgaatca ggtcacggta
    12241 ttccgccgca cgttcaaact ccatagtctg ggctgccgct gccattttgc cctttagctc
    12301 atcaatgatt ttgttatcct gccctttcag aaaatcagaa acctcctggg ccatagactt
    12361 gaaataagtc tcatccttct tacagatggt gtgggccatg cattgaccga tatggtaata
    12421 aaaacagacc ttagagggcg ggttggtaca cttacgaaaa gggaatatcc gatccagcaa
    12481 ccgcttgatt tcattggctg cccccacatc gggatagggt ccaaaataaa gacctccgtc
    12541 ctttttgacc tgacgagtga taatcaagcg tggatagcgc tcattggtga ttttgatgaa
    12601 aggataggac ttgtcatcct tgagcatgat attgtacttg ggcttgtttt ccttgatcag
    12661 gttgatttct aggagaagtg cctcaatatt agactccgta acaataaatt caaaatccac
    12721 aatttcagac accagagcct ctgtcttggt atcatgactt ccacgaaaat aggaccgtac
    12781 tcgattacgc agatttttag cctttcctac atagataatg gtgccatttt tatccttatg
    12841 aatgtagcaa ccagggctgg tcggcaagag ctctagtttt gatttaatca agttgttcat
    12901 agttccatta tagcaaaaaa agtagggaaa gatagtaccc tactcactag tctcatatat
    12961 ttttcggagg tttgcaacat cctcttcctg gataccataa aaggaacctg ctggttgcat
    13021 gacagacttc tcatctgtat ggtccaagcc aatcgcatga cctaactcat gttctgccgt
    13081 atggacaagg cgttcatagg agtagccata gtatggattg gacaaataat aatgattcaa
    13141 ccgcaccgtt acggacaaga attgccctgt taagagatta gtttgacttt ccgcctctcc
    13201 tgccacagga gtgcctccgt cgttcatctc cgtagccgta atatccgcct tactagactc
    13261 agtcacgagt tcaaagttaa aagcaccagt ttgattccag ttctggattg cttctaaata
    13321 agcctcttga aagcgtgaat ccatctgcgg atccaggtaa atacgagcag aggcctgtgc
    13381 ccaccttcct tcagaatgct ggtgactatc tgtctggctt aacttaggca gttgccctgt
    13441 tttctcccat tggtcaatac tttgttgacc aatttttact gaccgttctg cttgctttag
    13501 cgctccttga aaatccccgt tcagatacca gagaagtccg aaagcaagca cacataagag
    13561 cacaactatc caaaccagac gccaaaacaa acgccacaca aaagaaaaga aagcccctat
    13621 caaacgaaaa agccagcgca tgtctctcca cctttctagc aaataagaat tattttacta
    13681 aaagaagcta aaagaaatct aaatactgac tttttcatct taacgtccta ctattttttt
    13741 gagtaactgg atagctttgt attttaaagg cgatggatgg taacggaaag tacccgcttt
    13801 gcgtacaata tagccattaa aattctgttt aaaacgcaaa acaccatcac ttccatcaaa
    13861 aatcccttga atgcctagga aattgtattt aggtattcca cgttttatgc tttccaacat
    13921 aacatatttt tgaagcagtg caggggcata gaacttatta aactcagtgt aggaaccact
    13981 aaagagataa gtcgtttcct gaggcatata aacaaataaa ctcccagcta aaacaatatc
    14041 ttcttctcca tatttttcaa tcaagtctcg cgcttctgct tttcgaactt caaacgtttc
    14101 aaattgacta gaatattctc tcagttgatt ttgttttttc tcagaatgag gatttttact
    14161 caaatcaagt cgcaacttgt ccaagttttc ttctagttta ctttgttcac cttgcaattt
    14221 gctcatatac tccgaaaaat tcaagcttgc tatgagaaac tccgcttgtt ctccaaaagt
    14281 atcataaaaa tgctcataat attctaaact tttatcacta tattctctac gttcagaggt
    14341 ttcttttgtt atattcttaa aaatcgatag ttcttcacgt tttaactttt tcaaccgaat
    14401 gccaaaggtt tcagcctttt tcaccaaggg tttacccttt ttgctaaaac ttttaagcaa
    14461 actcttttca gttaattcag ttaaatcttt atagtataac caatctggtt ctccacctgg
    14521 gtaacctgtt gttaagccat caaattgata acctaaatca gtcaaacctt gaataatact
    14581 ttttttctca gcatctattg gattaccttg gctatcaaaa gtttgataag tttcataagg
    14641 ttttacaagc aactctaata caccattttg cttggcatat tcttttaact ctgcataaaa
    14701 aactggaaga gcatcttgtt gggtataaat cggccccgaa ttgagttcca tatgcagacc
    14761 acccagcatg ggcaagctat aaaccagagc tgcaacttga atttctcctt cttgtttcaa
    14821 agcaagataa acaattcgag cccctctttt ttctagcaaa tcccccatct ggacagattg
    14881 cataaaggaa cgagaagaaa cctgatcaga ataagtctga aactcttctt tcgtgagtgt
    14941 tgttagtgcc atatacttac tttctatgtt tttttcttaa tgttttacgg aaatcaagag
    15001 caagtcttaa cagaggatag agaggatgag tgggcattgt aaattcaccc aagtattctt
    15061 caatcgttgg attaaatttt tccttaaaat gataaagtcc accattgaga gagttttcaa
    15121 caccacctaa attttgccag accatacctc gctcaaaggc atagcgagcc gtttcatacc
    15181 atgttaaaat tggtgcattg taacgtttaa aatcatcatc cataccagca tatatattga
    15241 cagaggtagt accaaattcc aaactcaaag tagccgctaa aggaactctc gcttgaccta
    15301 catctatata ttcctgcaag aaggtcaatt cctctaacaa acgttctttt tccttcttct
    15361 gcgcttctac ttttgaagtt cgagtcgact cagtaaaggt ctcttccaag gctctatttt
    15421 tcgctaactg ttcttctaac tcttgcgaac gtttagaaac atccaaggtg gccaaggtga
    15481 tataggcctt gtccttaaaa ttatctaaca attttttata ataggcttca ttcctcaaat
    15541 gaatctcttt tcgcttctca gtttttttca tcaactccga aaatgaatct aatagttcca
    15601 gtccaccata ttgaatctca agccctttgt ttcgtgctgt tcgaatagcc tgttttgttg
    15661 acttggaaag tttatcttct tcaaaatttt ccttgtatat tttcgcctga atacgaggtt
    15721 gaatggtgtc tcccatttcc tccgtttttc ctgaccacct tactcccatt tgttgcaaac
    15781 tatcaataat agccagattt tcaggaaatt ctgtcttttc ctgattgatt aaactttgag
    15841 ataggcaaat acttgggtca aaagtcacaa aaaccgctct cttactgcga gcataggact
    15901 taatagactg aatggcaaaa ttcaagagtt ctttatcccc ataatccaat ataggtcctc
    15961 ttgggatgta aaacatttta tagcctagcg gaagagttct aatcaaaata ctagctgtcg
    16021 ccagtaattt ttcttccctg taaacaccaa acttctcatg ttgccaatta gacttaactt
    16081 cctcccaagc actactttgt aatacattgg ctaattcatg ttctttgaca aactgatcat
    16141 attctaatgt gggaatgcca atttgataac ggtacatttc ctactctctt tcctccagta
    16201 ttttattact attctactac tttcgtttga aaagtctagt gaaaacatat tttattttag
    16261 ttctactccc cctatgctga agttcaaact aagtcagtct ctcttctaat ttgaaatcaa
    16321 ttggtagggt tgttaaaaaa acttccaatt gtttttccca gtagtaccac tcgtgagttc
    16381 cagcgctatg gctataggtc acatcaaaac ctagtttttt gagatttttc actgcgagat
    16441 tattggcttc gtacaagaaa tcctgttcgc cacaccacgc ccaaagtttg gtctttttat
    16501 ccgatttttt agccagactt tcaagagaat agggactagt tgtccagtct ctaatctctc
    16561 caaaaacacc tctccagtag gctggacttc ccagattttg actttcagga gaaaagtttt
    16621 gaaagctgag ggcacctgaa aaactagctg catgagaaaa acgatttgtc gcaagagcca
    16681 gtttgaaaca gccgtagcct cccatagaaa gaccagctat aaaggtcttt tcacgcttgc
    16741 tagtcatatt agggaagaag cgtttcagaa cctgtggcaa ttcctctgct agagccgtgt
    16801 agtagtcaaa accatactgg gtatcggtgt accaaccatt gctggtattg ggcataacaa
    16861 cgatgagatt agttcctcga agcaagcgtt ctacattggt ccgcttaagc caactattat
    16921 gatttccaga cattccgtgc aaaaggtaca agacgggaat atcttcacac tctggttctt
    16981 ccactcgatt ggcatcaggg tagaggacat tcatccccca ctccatatcc aatacttgtg
    17041 agtaatactc gattttcatt actgccatga ttttctcctt ctatttttct ataagaaaaa
    17101 gccgaaactc gactttctct ctgtttattt caacgattat tttgcttcca tgactactgg
    17161 taaaatagct ggacgacgct tggtttggtc aaagagatac ttggtcaaat tatctcgaac
    17221 cttcccttta agatctgccc agtcaaagtc atctccttga agataatctt ctaccgtttg
    17281 gttaatcaat tctgaacttt cacggagaat atcgcgactc ttcttgagat aaacaaatcc
    17341 acgcgtgtga acacgagctc tagccacaat tttcttctca cgacggttga ctgtaatagc
    17401 cacgatgaaa attccatcct ctgacaagac cttacggtca cgaagaacaa catttccaac
    17461 atcaccaata gcattcccat caattaagat atctcctgct gaaaccgatc cagctggaac
    17521 aaagtctcca ttctcgtaag ccatggtcgt ccccttttta ggaatgaaga tgcgttctgg
    17581 caacatccca actgccatgg cagccttagc gtgagcatcc aactcacgat actccccttg
    17641 gacagggaag aggtacttag gttgcaaaag attgatcatc agctgcaaat cacgcacatt
    17701 tccgtgccct gatacatgta aactttgggt aatcaatttg acaaccccac ctgcctgata
    17761 aatcatattt tccacacgcg caacaaaggc ttctttagca atagacggag ccgtagcaat
    17821 atagaccagg tccccatcct tgatttctac ataacgatgg cgaccaatcg acatcttacg
    17881 aagtccattg ataggttcac ccatacgacc tgtctcaaga ataatcaact catggtcttc
    17941 aaagcgagac atatctttag gcttaatcaa gagaatttcg ttggctaaag acaacttctt
    18001 aagacgaatc gctgtgcgga cgatattttc aatatcaaat cctgtcaaga cgatacgtcg
    18061 acctgtttta tccgcagcgt caaaaatctg ctgaatacga gaaagattac tggaaacagc
    18121 tgcaacgatg atacgacctt cccagtcagc aatagtttgg gtaatttcat ccctaacttc
    18181 actttcacta gccacctgaa tattgctgtc tgcattggcc gaatcactga ggagagccag
    18241 gacgccgtca cgaccaatct ctgccaaacg agcaaaatca gttgcataag attcactagc
    18301 cgtttggtca aatttgaagt cacctgtata aacgatgctt ccttccgatg tcttcaagac
    18361 aattcccaga ctctctggaa cggagtaagt cgtagggaag aaggaaacca ctgtcccacc
    18421 aaaatcaatc tccgtattct catcaatgac atggaaatca ttaaatttct taacggcatc
    18481 atttcctttg acaaagagct ttgccaactc aatggtcaac tcagacccaa atacaggaac
    18541 tttagcctct gccaagagat aaggtagagc accaatggca tccgcatgcc cgtgggtcaa
    18601 gaaaacccca gcaatacggt cgctattttc aaaaaggtaa tccatgtttg gaatcaccac
    18661 atcgacccct aattgttcat tttcaggata ttttaaccct acattcaaaa caaaaatgga
    18721 ctctccaatt tcagcaatgt acatattttt tccattctca cgcacaccac caagtgttgt
    18781 taaactgata ttactcattt ttcctccaaa atcttagttt atcttgatta tagggcaatt
    18841 ctaccctctt attctaaaag ttctgatact ttcagccgaa tcttttccta ccattatacc
    18901 atttttttga tgattttcaa aatgaaggtc tgttttcaaa aaagagttga tttcccaact
    18961 ctttcctaac ttctactctt tttccatcaa aaaatcataa atttcttgca ccgtacccag
    19021 cgccatcatt tcttggtctt taacggtttg tttgagattt tggtaaattt gactttctcc
    19081 tatctcccgc tttggcgcct ctttattgac tgtcatcaca ccatctttta tcgtcacaaa
    19141 gcctagttct tcaaatactt gaatcatctt gaccagcaag atttgttgaa tattaagata
    19201 tgcagccaaa tctttcagct tgtagcgaat atcaaactct gggaaccggt aaatagtctt
    19261 gtacaatttg gcaaactgat ctctagtccc ataacctgtc agataataag ccttgtcaat
    19321 atcatttttg aaatagacag cagagaaatg ctgttcctga aaaatggtct tcagctgagt
    19381 aatatcctct ggaatgtttt ttacgacaac agcttcacta gccgcaagat ttggcagttc
    19441 tccaggaaaa tccaagactg gaacaccttc tggcaagact gcattttttc cacgaatgtt
    19501 aaaaagttga acaccttcca ctcgcgcatc caccatcatc aactggaggg cagtttggcc
    19561 attccattgg ttgacagaca atttaaccgc taactctaga ttcttggttt gagaaaactc
    19621 tgtcgcccat ctgccttgac caaaggctac cacttcaaaa ctcgcctcac ccttggaaat
    19681 tttcagcttt agatgggcat tacctgcccc catagtacga gcactttcga cctgaaaatt
    19741 cttgatataa aaaataggtt tctgattatc cattccaaaa ggagctaaac gttcaaaact
    19801 tttgaccgtt tccaagctaa gtgcctccaa atccaactct tcatctaggt ttaacttatt
    19861 cttgccacca gcatctgcac ctttttcacg aacataatct tccaaaacct gagataaatc
    19921 tgagagttgc tcaacttcca acgtcatacc cgctgcacct gcatgacctc caaaggcgat
    19981 gaagaggtct cgatggggat ccagagcttc aaaaatatcg accgcttcca cactacgagc
    20041 actgcccttg gcacgaccgt cttctatatt aagaacaatg actgtctgtc ccaattcttc
    20101 caataaacga ccagccacga ttcctagaac cccaggattc cagccttcct tggccaagac
    20161 ctgaaccttc ttctcaggat ccaccatggt cttggcttct tcatagatag actgaacgat
    20221 ttccttgcgc tcttcgtttt tctggtgaat cataagggca atctcatgcg cttcctcatc
    20281 atcaaatcca gtcaacaaat caatggcagg attgggatca tccaagcgac ccaaggcatt
    20341 caaacgagga gcaatctgga aaccaaccgt ttcttctgtt acttcgttgg caccaatccc
    20401 agccatgtcc agcatttctt gcagaccaat gcgctgggta tgacccaaca tttccagacc
    20461 atattgaact aagatacgat tttcatccgt cagactcacc atatctgcaa tagttccaat
    20521 agcgaccaaa tcaagcaatt ccacttgcac ttcttctaac agggcacaag ccaacttgaa
    20581 agcaactcca caaccagcca aatatttaaa aggataatcc gcatctggat gttcaggatg
    20641 gacaatagca taagcatctg gcagggtttc aggcatggaa tgatggtctg tgacaatgac
    20701 atctactccc atagactgag ccaatgcaat agcctcatga ccagcaaccc cattgtccac
    20761 cgtcacaatc aaggaaatcc cttcttgctc gataaagtat ttataaacac tagcattagg
    20821 gccatagcca tcggtaaaac gatttggcag gtaaactcgg cactcagcac caagttgttc
    20881 caaactttcc ttcacaatag aagccgaagt catgccatcc gcatcatagt ctccataaac
    20941 gagaatattt tccccttctt caatagcctg acgaatccgc tccactgcct tgtccatatc
    21001 atggagcaga taagcatcat gtaagtcctc caaggaaggt tctaaaaact tcttcagact
    21061 ttcttggtcc tgaatccctc tctcaaacaa taaccgagcc acctcaggac ccagtccagc
    21121 cttcttggct atctttgtaa aatccgcatc ttctacctgc agggcaaact gccattcata
    21181 agtaggtgtt atcaaaaaga catccactct ttctaagaat tctattgctt cattataaca
    21241 tgatttagac gttttctcta tccagattgc ttttttataa cattttatag tatattgaaa
    21301 ctagaatagt acacctctac ttctaaaata ttgttagaaa tcgatttgac tgtcccgatc
    21361 gatttgtcct gttcttattt caatatagtg aattttttca gatatggttt gacaagaaca
    21421 ttcttttatt gtagaatcgt gttataaaat ctaacataaa ggagatctct catggcttta
    21481 gtagaattta aaaacgtcga aaaatattac ggagactacc acgcactccg caacatcaat
    21541 ctccgttttg aaaaaggaca agttgttgtc ctgcttggac cttctggctc tgggaagtcc
    21601 actcttatcc gtacgatcaa tggtttagag gctgttgaca aaggaagtct cctagtcaat
    21661 gggcaccaag ttgctggtgc cagccagaaa gatttggtac ctcttcgcaa ggaagtcggc
    21721 atggtttttc aacattttaa cctttataca cacaaaactg tgttagaaaa cgtgacactt
    21781 gcgcccatta aagttctagg aattgataaa aaagaagctg aaaaaaccgc ccaaaaatat
    21841 ctggaatttg taaatatgtg ggacaagaaa gattcctatc ccgccatgct atctggtgga
    21901 caaaaacagc ggatcgccat cgctcgtggt cttgctatgc atccggaact cctcctcttt
    21961 gatgaaccaa catctgctct tgatcctgag actatcggag atgttctagc agttatgcag
    22021 aaactggcgc atgatgggat gaacatgatc atcgttaccc acgaaatggg ctttgctcga
    22081 gaggttgcgg accgcattat ctttatggcc gacggagaag ttttagtaga tacgacagat
    22141 gtcgataact tttttgacaa tccaagcgaa gctcgtgccc aacaattcct cagcaaaatt
    22201 atcaaccacg aaagtgacaa agtcaaataa ggaggcgcct atgaaaaaaa attcttttta
    22261 tcagcattat tgattagcct tttcggcctt gctgctgcca aaccagtcca ggctgatact
    22321 agtatcgcag acattcaaaa aagaggcgaa ctggttgtcg gtgtcaaaca agacgttccc
    22381 aattttggtt acaaagatcc caagaccggt acttattctg gtatcgaaac cgacttggcc
    22441 aagatggtag ctgatgaact caaggtcaag attcgctatg tgccggttac agcacaaacc
    22501 cgcggccccc ttctagacaa tgaacaggtc gatatggata tcgcgacctt taccatcacg
    22561 gacgaacgca aaaaactcta caactttacc agtccctact acacagacgc ttctggattt
    22621 ttggtcaata aatctgccaa aatcaaaaag attgaggacc taaacggcaa aaccatcgga
    22681 gtcgcccaag gttctatcac ccaacgcctg attactgaac tgggtaaaaa gaaaggtctg
    22741 aagtttaaat tcgtcgaact tggttcctac ccagaattga ttacttccct gcacgctcat
    22801 cgtatcgata ccttttccgt tgaccgctct attctatctg gctacactag taaacggaca
    22861 gcactactag atgatagttt caagccatct gactacggta ttgttaccaa gaaatcaaat
    22921 acagagctca acgactatct tgataccttg gtcactaaat ggagcaagga tggtagtttg
    22981 cagaaacttt atgaccgtta caagctcaaa ccatctagtc ataccgcaga ttaaggagga
    23041 taccctatga cagatttatc atcttggaca gcctattttc aggattttgg acaatttttc
    23101 aatggtttcc tctttactct tgccctagcg attggatcct ttatcctcgc catggtctta
    23161 ggagtcttct ttggtgccat gtcaaccagt aaacgtccaa ttttacgcat tttagctcgc
    23221 atctttgtgg aattttacca aaacactccc ctcttggtgc agtttgttat tgttttttat
    23281 ggcctacctc ttatcagtga ccatactatc atgattccga tttattggac agctgttctc
    23341 tgcgtgggac tctatcacgg cgcttatatc gctgaggtta ttcgttcagg gattcagtct
    23401 ttacatcctg attgccctca tctacttcag ctttaaccta gcaatttcta acctgtctca
    23461 tatgctagca aaacgttggc aacaagctgc agaataacaa attagctctc tagttcattg
    23521 gagagttttt tgatgatagt agatatttat agacctcaat ttgacaccat acattttcta
    23581 tgataaaatg taacaaattc atttacaaca aatcgaaatc taaatgaaat ggaattttct
    23641 atgaaatcag tcaaaggact actctttatc atagctagtt ttatcttgac tcttttgact
    23701 tggatgaaca cttctcccca attcatgatt ccaggactag ctttaacaag cctatctctg
    23761 acttttatcc tagccactcg tctcccacta ctagaaagct ggtttcacgg tttggagaag
    23821 gtctacaccg tccacaaatt cacagccttt ctctccatca tcctactaat ctttcataac
    23881 tttagtatgg gcggtttgtg gggctctcgc ttagctgctc agtttggtaa tcttgccatc
    23941 tatatctttg ccggcatcat ccttgtcgcc tatttaggca aatacatcca atacgaagct
    24001 tggcgatgga ttcaccgcct ggtttaccta gcctatattt taggactctt tcacatctac
    24061 atgataatgg gcaatcgtct ccttacattt aatcttctaa gttttcttgt tggtagctat
    24121 gcccttttag gcttactagc tggtttttat atcatttttc tatatcaaaa gatttccttc
    24181 ccctatctag ggaaaattac ccatctcaaa cgcttaaatc acgatactag agaaattcaa
    24241 atccatctta gcagaccttt caactatcaa tcaggacaat ttgcctttct aaagattttc
    24301 caagaaggct ttgaaagtgc tccacatccc ttttctatct caggaggtca tggtcaaact
    24361 ctttacttta ctgttaaaaa ttcaggcgac cataccaaga atatctatga taatcttcaa
    24421 gccggcagca aagtaaccct agacagagct tacggacaca tgatcataga agaaggacga
    24481 gaaaatcagg tttggattgc tggaggtatt gggatcaccc ccttcatctc ttacatccgt
    24541 gaacatccta ttttagataa acgggttcac ttctactata gcttccgtgg agaagaaaat
    24601 gcagtctacc ttgatttact ccgtgactat gctcagaaaa atcctaattt tgaactccat
    24661 ctaatcgaca gtacaaaaga cggctatctt aattttgaac aaaaagaagt gcccgaacat
    24721 gcaaccgtct atatgtgtgg tcctatttct atgatgaagg cacttgccaa acagattaag
    24781 aaacaaaatc caaaaacgga gcttatttac gaaggattca agttcaaata agtaatcata
    24841 ctctcctgga atttcccagg agagtttttt atagccaaat gaaataagac cggaacgatg
    24901 gaattttggc attcaaatca attgataaga atattttata gtggagtgaa ataggatacg
    24961 aacaaattga ttaggaaaat caaatgaatt tatagaaatc ttttagcagt tatgttatcc
    25021 tattctagtt tcaaaacgct atagaagcag cattgtgcta gtctagattc agtttactat
    25081 actaaaacga gtagcttgaa atcaaaaaac ccaccctcac aggcaggttt tatctgtatt
    25141 attcagctag attatgcttt accttctgaa ccgaatacgt cgatacgttc ttcaaccgat
    25201 gcttggatag cttttacacc gtcagccaag aatttacgtg ggtcgaagag ttttttcttg
    25261 tcgtattctg cttcgtttgc ttcgtagtca cgagcaaatt tacgagttgc gttagcgaat
    25321 gcgatttggc attctgtgtt aacgttaact ttggcaacac caagtttgat agctgcttgg
    25381 atttgctcat caggaatacc tgatccaccg tgcaatacga ttgggaatcc tggaagagct
    25441 tctgtcaatt tttgcaagtg gtcaaggtca agaccttccc agtttactgg gtaaggaccg
    25501 tggatgttac cgataccagc tgccaagaag tcgataccag tttcaaccat tgctttagcg
    25561 tcttcgattg gagccaattc acctttaccg atgattccgt cttcttcacc accgatagta
    25621 ccaacttcag cttctactga gataccttta gcgtgtgctt tttcaacaac ttctttagcc
    25681 aatttaagat tttcttcaac tggaaggtgt gaaccgtcaa acatgattga agtataacca
    25741 acttcgatac actcaagtgc atcttcgtag tgaccgtggt caaggtggat agctactggt
    25801 acagtgatac ccattgattc aacaaggtta gcgatcaagt tgcgagcaac tttgtaacca
    25861 cccatgtatt tagcagcacc cattgaagtt tggatcaaaa ctggagcttt tttagcttct
    25921 gctgcgcgca agatagcttg agtccactca aggttgtttg tgttaaatcc accaactgca
    25981 taaccgttgt cacgggctgc ttggacaaat ttttctgctg aaacgattgc cattttatca
    26041 ggcctcctgt atatttttat gggtcatccc atttacattg ttcattttat cactttttgc
    26101 caaaaaaatc tagtttttcc cgcagtttcg attgattttc ttctaactcc atctatgtaa
    26161 accctttctc tccctagtct tgggcgactt ttggaaaatc tataaagaag gttaaacgat
    26221 tctcctccat ctcgaaacga taagctaatt tttcatgttc taatagactc ttaaccacaa
    26281 agagccccat accagacccc ttgaccttgc gactagcatt gtcagaaaaa gactgggcta
    26341 gtttttcttg ttcctctgag ctacagctat tttcgataaa aagttctcct tctctttctc
    26401 caattcgaac taagccacct ggaacagagt gcttaatggc attgctgatg agattagaaa
    26461 gaatcaactt cataactgat gggtttagat aagcctgctg atgggtcaaa ctattgtcta
    26521 tctggagctc tctttccttg gctagcaagg cataatcttt gaccagattt tgcgtcatct
    26581 ggaggaggtc aattgtttcc ctatcatctc gcaattcctg cacagaagag agggaaagta
    26641 tctgcagaac atggtgattg agttcatcca caatccccaa ggcaactccc agatactggt
    26701 ctctatcctt ataacgaccg atattctctc tcatattttc gattaggatt ttcaaactag
    26761 ccagcggtgt tttcaattca tgagaagctc ctcgtaggaa ttcgaccttc atcttctcca
    26821 gctggagaat ggcttcattc ttttcatgca agtccgcaat aacagtcaag agatgctggt
    26881 agaggctatt gatttgttcc ttgagattac ctatctcatc cttagaatcc acgcgcaatc
    26941 gcacttggga atccaggtcc atcatccgac gggtcacccg cttgatttcc aaaatcggtg
    27001 caacaatagt ccgagcgtag atgtaggcca ccaagaggga aatcagaaag gaggccagca
    27061 aggtataggg aagaaactgg agactgattt gctccgcttc cttttgtaaa tccatggaag
    27121 ctagaaactg gagaatcata gtaccaccgt cttgcgtttt cacctcgcgc tcctcaataa
    27181 agagagaggt tgtctggcgg tctgtgtcca gaggaagact gtccttgact tctaacttgt
    27241 cctcggtcat ctcacctttg acggtcccct tgatatcact agtctgggaa tacaaatcta
    27301 acacttgctc gatactctgc ctatctttcc cttctaggga ctgggcaatg gctgttgcct
    27361 tttgaccaat ggtttcctga cgatgactca gataagtcga aggaaaaaga aaataaatag
    27421 ctaaatgaag gcagataacc agaacactaa atatcgagaa ggtatagata aatatctttg
    27481 caaataaacc tgttcgtttc attttcgctc caatttataa ccaacattgc gcacagtgag
    27541 gatacaatcc aagtctagct ttttccgcaa ttccttgata taaacatcaa taacacggtc
    27601 aaagggaacc tcatctgtcg ctttccagac ggcatcgata atctgagacc gagtcaaggc
    27661 ccggccttca tttttcacta gatagtccag aatttccaac tctttggcat tgataggcac
    27721 ttcttgacct gcgaggcttg cactgtagct ttcaaagtcc accttggtat ccttgtaaga
    27781 aaagattcgt cctgtatcgt agtagcgctt gaaaatcgcg tccaccctca cttttaagag
    27841 ggagagggag aaaggttttt ccagatagcc atctgccaaa gaggcaaagg cactcatctt
    27901 gtattcctca tcctgaaaag ctgtcaacat caagacagga acctgactgg ttttacgaat
    27961 ctcagctaga acttctaagc cgttaagctt gggcatctgg atatccagta aaaccagggc
    28021 cacctcatag ctagaaaatt gctccagagc ttcctgaccg tccgctgcct caatagtttc
    28081 atagccacaa tccgtcaaat aatcactgac cccctcacgg atcatctctt catcttctac
    28141 aattaaaatt ttcatacttt aactgctctc tattttttat ttttcttaga ataaatacct
    28201 actctatttt ctattatagt ctcttgctgg ccttttgtct gtaagtaact gatcactaga
    28261 taaaacgttg tgaaattcct ttctcataaa ttccatagct ttagtatatt atatttaagc
    28321 aataaagtac aaagaaaaca actgaaagca atgattttca ccactgcttt cggatttatt
    28381 ttgaattgtt aaatagccat tcctatccac tattcttgaa tagaaacaca agatgcaatc
    28441 tttattccag actcattttt tcaaatttat tcaccatcca gcaagagctc ttttggttgt
    28501 tttctaagga gattgcttga agcaagcgcc ataacgagaa ccactagaac caaggcaagg
    28561 acaaaaatga tgataaagtc tgatgtctga atagaaatgt ctaggctcga caaggtcttg
    28621 ctaaagccat ctacttctgc accaccacca aggttagagg cttgagccgc cttactagcc
    28681 tgtttggcaa cacctgaagt cacattggca aggacagtgt ttccaattgc acgggcagtg
    28741 taattagcta ggaagtaagc agaaactaga gcagggatag caatcaagat agattcggtg
    28801 atgaattgac ccaagatact tgcctgcttg aggccgatag agaggagaat tcccacttcc
    28861 ttgcgacggg cgttgatcca aaggctgagc aagagggcaa ggaggagaac tgagaagctc
    28921 aagctacccc agaagaggag gttggccatc ttgtacatac cagatataga ttgctcaaga
    28981 gctgggtagt tagaggagct cttgacgagt gtgtagctct tccagttgat accactgatg
    29041 ccattcaact ctttcataac atcatccaag ttcttgtctg ctgttacaaa gaaggttgcg
    29101 tccccataaa tggctgtgtc ttctgtgtat ccataaagtt ttgcagcagt gtgaatgtct
    29161 gtaatagctg tgttttcgta aagttcttgt gagtaggtta ctgctgactt attatgacca
    29221 tcaaagagtc ccttgattgt cacttcaact gtttccttgg ctcctttttc attatctgca
    29281 tcgtagatat tagagtccag tttaaccttg tcccctactt tccagccgtg tttggctgcc
    29341 aagtccttgt gcaagaggat tttatccttg tcgtcgttgg ttaagtgctc tccttcgact
    29401 agtttataag aaccagagac aaacttgtct tctttagagg agtcattgac acctgtaatc
    29461 atcaagctac ttccaaaacg tttggcacga tcagcagtga gattcttctt ggtttctggc
    29521 gtttcaatca ggtcatatcc agtcaaatct ccgatagcgt tgatacgttt gacataagac
    29581 tcaatggcct tgttttcggt gatttttttg atgtcttcac ccttgatatt cccagcaccg
    29641 cgaggcgttc cttggttgac gcgacgattg atttgcatgg agaagctatt ggtgatattt
    29701 ttaaaggtct cctgagaagc cttggcagta gctcccttga ttgacaagcc gaccaaactc
    29761 aagctcgcca tgaggagaat aatcaggaag atgacaatcg atttgaaaaa cttccttgta
    29821 acataggcaa atgcgttgtg taacatagat tccctttcta gattttgttt taatcattct
    29881 atcaaaataa gctcaaatta tttactagta ttgcgcgttt cagtcagttt cttatccttt
    29941 aattcaagtg taatatctga cgcttgtgcc acttctttac tgtgagttac gacaatcaca
    30001 catttacctg ttttctgggc aagtgatttg agtagttcga caatatctcc agcagtttta
    30061 ggatccagat ttcctgttgg ctcatcagct agaataactg gagcttctga gaccaaactg
    30121 cgagcaatgg caacacgttg ctgttgacca cctgataact ggagaacatt ccgcttgatc
    30181 tggctttcat ccaaaccaag ctcaagaagt gtattcttgc ttgccttttt gttgaccaat
    30241 cggatatttt ccagcggaga aagataatct atcaagttat aattttgaaa gaccagggaa
    30301 atatggtgca tgcgatggta agaatagccc ttcttacgaa tatcctctcc ttgaaaaagg
    30361 atagaacctt caacaggact atctagacca gcaagtaggg acaagagtgt ggattttcct
    30421 gctcctgact ccccaataat actgtaaaat tttccgggtt caaaattata attgatctga
    30481 tataggactg cttcagcagt attcttataa cggtaggtaa catcttgtaa ttgtaataaa
    30541 gtcatgattt ctccttctta actaatagat gataaaattt ctttcggtga ttttctaaat
    30601 aagaatagga aacaaagggc tacagataag caactaagca gaactagaaa aacataggat
    30661 tctgcaaaag ataagatgct agttgataaa ctgcttgctt tggctagtgt atcttgtaag
    30721 cttacctgat ctccacttgc tagtagagtt tggagtaggt aagttgtgat tccgtttcct
    30781 gcaacaaatg ctggaagcaa agctccaaga gataccaaaa ctacctctaa acagaattgt
    30841 aggaagatcg agctcttgcc ttttccaagt gcaagtaaaa tccccacttc atagacccgt
    30901 tctctcaacc agagagacaa aaccagaatt aaggctccag ctcctgctat caacatccca
    30961 taaaggaaga tggtcaggaa ggtttggaaa gttgcaactg agtctttgat ttgttcaaaa
    31021 gccttgtttt ccttttcgac ttggtagcct tgattttcca aggccaagtt ttctacctgc
    31081 ttcatgagtc cgtccatttc cttaggattt tctacataga agcgtgctgc actgacttga
    31141 gcttcactat tgcccaaaag ggtttggcta ctttcataat ctgtaaagac ttgattttca
    31201 ctgaagtcag aagacaagcc tgtgaatttc tcttgttttt taccagaaaa gatgccgata
    31261 atctcaaact ctactgtttg tccttttcca gattcagact gaccagcatc caagccaatc
    31321 ttgtcatgaa gtgaaagacc gttcttctta gccaattctt cgtggataag gattttcttg
    31381 gaatcccctt tttgaaggtg tcgcccttct tttagattga aagccgaact ggtaaaggtt
    31441 acatccttgg atgaatcctc aagagccgtt aagctaacca agttattgtc tgcagctgat
    31501 aaatcatcac gctccacgct ctgctcgcca gtcactgctt ccttgtcttt tagttttgcg
    31561 accgtctcaa gttcaggaga gacattttcc agccccttaa tcttgcttac agatgctagg
    31621 tctgacaact tgaatgtctg accattctct atcttcttaa tagaaaaaga tgtattgagt
    31681 gatttataaa gattgctttc tactgttttg ttggacttca tcagagtcaa acaggctgaa
    31741 attccggcca ataagaccaa taaaatcaga aataaaataa aacttctcag tcgctttctg
    31801 ctgacataag cccaagatct ttggattgga ttcatttgtc acctccatat ttgtaagact
    31861 attataaaac ccaaatatga aatgtttatg aaatacgaaa aaaaaaa
//
LOCUS       DAVLXH010000020        30958 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00028199
            SAMN33607166-rid17955573.denovo.020, whole genome shotgun sequence.
ACCESSION   DAVLXH010000020 DAVLXH010000000
VERSION     DAVLXH010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607166
            Sequence Read Archive: SRR23725544
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 30958)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30958)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721421.1
            Genome Coverage       :: 115x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:42:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,210
            CDSs (total)                      :: 2,161
            Genes (coding)                    :: 2,023
            CDSs (with protein)               :: 2,023
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 73 of 138
            Pseudo Genes (incomplete)         :: 60 of 138
            Pseudo Genes (internal stop)      :: 40 of 138
            Pseudo Genes (multiple problems)  :: 31 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30958
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607166-rid17955573.denovo.020"
                     /strain="AUSMDU00028199"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1349"
     gene            367..1530
                     /locus_tag="VYO11_001033"
     CDS             367..1530
                     /locus_tag="VYO11_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HEV1595620.1"
                     /translation="MNRIRVSKRVEKKLAKGLVLLEASDLENVNLKDQEVEVQGQEGN
                     FLGTAYLSQQNKGLGWFISKDKVAFNQAFFETLFRKAKEKRNAYYQDDLTTAYRLFNQ
                     EGDGFGGLTVDLYGDYAVFSWYNSYVYQIRQTISEAFRQVFPEVLGAYEKIRFKGLDY
                     ESAHVYGQEAPDFFTVLENGVLYQVFMNDGLMTGIFLDQHEVRGSLVDGFSMGKSLLN
                     MFSYTAAFSVAAAMGGASQTTSVDLAKRSRELSQAHFQANGLSTDEHRFIVMDVFEYF
                     KYAKRKDLTYDVIVLDPPSFARNKKQTFSVAKDYHKLISQSLEILNPGGIIIASTNAA
                     NVSRQKFTEQIDKGFAGRSYQILNKYGLPADFAYNKKDESSNYLKVISMKVSK"
     gene            1527..2204
                     /locus_tag="VYO11_001034"
     CDS             1527..2204
                     /locus_tag="VYO11_001034"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HEV1595621.1"
                     /translation="MKLIVSVMPRSLEEAQALDATRYLDADIIEWRADYLPKEAILQV
                     APAIFEKFAGRELVFTLRTRSEGGEIDLSPEEYIHLIKEVAQLYQPDYIDFEYYSYKD
                     VFEEMLDFPNLVLSYHNFQETPENMMEILSELTILNPKLVKVAVMAHTEQDVLDLMNY
                     TRGFKTLNPEQEYVTISMGKVGKVSRITADVTGSSWSFASLDEVSAPGQISLASMKKI
                     REILDEA"
     gene            2194..3048
                     /locus_tag="VYO11_001035"
     CDS             2194..3048
                     /locus_tag="VYO11_001035"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HEV1595622.1"
                     /translation="MKLDGYTRLTAVVANPIKHSISPFIHNRAFEATATNGAYVAWEI
                     EASDLAETVANIRRYQMFGINLSMPYKEQVIPYLDKLSDEAHLIGAVNTVVNENGNLI
                     GYNTDGKGFFKCLPSFTISGKKMTLLGAGGAAKSILAQAILDGVSQISVFVRSVSMEK
                     TRPYLDKLQEQTGFKVDLCALEYVSELQARIAESDLLVNATSVGMDGQSSPVPENIVL
                     PETLLVADIIYQPFETPFLKWARSQGNPAVNGLGMLLYQAAEAFQLWTGKEMPTEEIW
                     QSLTEKYQ"
     gene            3067..4134
                     /locus_tag="VYO11_001036"
     CDS             3067..4134
                     /locus_tag="VYO11_001036"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HEV1595623.1"
                     /translation="MKIRIDIPHHPYDIQIEKGCMAQAGQWLRELWQPQKVVIVTDNH
                     VASLYAEKVKLSLEDAGFQVAVFDFLEGEERKNLTTVQKVYEFLVKQGLTRSDGIVAL
                     GGGVVGDLAGFVASTYMRGIHFVQIPTSLTAQVDSSIGGKTGVNTPFAKNMVGTFAQP
                     DGVLIDPLVLETLGKRELIEGMGEVIKYGLIEDPELWALLTGLNGSVESILEHAETLI
                     EHSCQVKRKMVVEDELDNGIRLYLNFGHTIGHAIEATAGYGKVMHGEAVAMGMVQISK
                     VAEEKGLMPAGITQSITEMCQKFGLPVDYENWKVDKLYQALTHDKKARGNTLKLVLVP
                     ELGSATIHPVSLEEMKDYLVK"
     gene            4144..5310
                     /gene="aroC"
                     /locus_tag="VYO11_001037"
     CDS             4144..5310
                     /gene="aroC"
                     /locus_tag="VYO11_001037"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HEV1595624.1"
                     /translation="MRYLTAGESHGPRLTAIIEGIPAGLPLTAEDINEDLRRRQGGYG
                     RGGRMKIENDQVVFTSGVRHGKTTGAPITMDVINKDHQKWLDIMSAEDIEDRLKSKRK
                     ITHPRPGHADLVGGIKYRFDDLRNSLERSSARETTMRVAVGAVAKRLLAELDMEIANH
                     VVVFGGKEIDVPENLTVAEIKQRAAQSEVSIVNQEREQEIKDYIDQIKRDGDTIGGVV
                     ETVVGGVPVGLGSYVQWDRKLDARLAQAVVSINAFKGVEFGLGFEAGYRKGSQVMDEI
                     LWSKEDGYTRRTNNLGGFEGGMTNGQPIVVRGVMKPIPTLYKPLMSVDIETHEPYKAT
                     VERSDPTALPAAGMVMEAVVATVLAQEILEKFSSDNLEELKEAVAKHRDYTKNY"
     gene            5320..6423
                     /locus_tag="VYO11_001038"
     CDS             5320..6423
                     /locus_tag="VYO11_001038"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HEV1595625.1"
                     /translation="MAKTIYIAGLGLIGASMALGIKRDHPDYEILGYNRSQASRDIAL
                     KEGMIDRATDDFASFAPLADVIILSLPIKQTIAFIKELANLDLREGVIISDAGSTKST
                     IVDAAEQYLAGKSVRFVGAHPMAGSHKTGAASADVNLFENAYYIFTPSSLTSQDTLKE
                     MKDLLSGLHARFIEIDAKEHDRVTSQISHFPHILASSLMEQTAVYAQEHEMARRFAAG
                     GFRDMTRIAESEPGMWTSILLSNSETILDRIEDFKERLEAIGQAISKGDEEQIWNFFN
                     QAREQRQTMEIHKRGGVDSSYDLYVDVPDEEDVILRILELLRGTSLVNIHINEENRED
                     IHGILQISFKNAQDLERAEHLITENTDYTVVIK"
     gene            6434..6772
                     /locus_tag="VYO11_001039"
     CDS             6434..6772
                     /locus_tag="VYO11_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF/YmcA family competence regulator"
                     /protein_id="HEV1595626.1"
                     /translation="MSNIYDSANELSRGLRGLPEYKAVKAAKDAIAADAEASKIFTEY
                     LAFQEEIQKLAQTGQMPDASFQAKMEGFGKQIQGNSLLSEFFTKQQQLAIYLSDIEKI
                     VFEPVSELLK"
     gene            6864..8147
                     /gene="aroA"
                     /locus_tag="VYO11_001040"
     CDS             6864..8147
                     /gene="aroA"
                     /locus_tag="VYO11_001040"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004236106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HEV1595627.1"
                     /translation="MKLKTNIRHLHGSIRVPGDKSISHRSIIFGSLAEGETKVYDILR
                     GEDVLSTMQVFRDLGVEIEDKDGVITIQGVGMAGLKAPQNALNMGNSGTSIRLISGVL
                     AGADFEVEMFGDDSLSKRPMDRVTLPLKKMGVSISGQTERDLPPLRLKGTKNLRPIHY
                     ELPIASAQVKSALMFAALQAKGESVIIEKECTRNHTEDMLQQFGGHLSVDGKKITVQG
                     PQKLTGQKVVVPGDISSAAFWLVAGLINPNSHLVLQNVGINETRTGIIDVIRAMGGKL
                     EVTEIDPVAKSSTLTVESSDLKGTEIGGALIPRLIDELPIIALLATQAQGVTVIKDAE
                     ELKVKETDRIQVVADALNSMGADITPTADGMIIKGKSALHGARVNTFGDHRIGMMTAI
                     AALLVADGEVDLDRAEAINTSYPSFFDDLESLIHG"
     gene            8140..8616
                     /locus_tag="VYO11_001041"
     CDS             8140..8616
                     /locus_tag="VYO11_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HEV1595628.1"
                     /translation="MAKVLLGFMGAGKSTIARGLDPNYLDMDALIENRLGMSIANFFA
                     EKGETAFRQVESEVLADLLQTDQVVSTGGGVVISQRNRDLLKTNTDNIYLKADFETLY
                     LRIAADKDNQRPLFLNNSKEELVAIFQERQAWYEEVASRVLDVTKLSPEEIIEELR"
     gene            8613..9461
                     /gene="pheA"
                     /locus_tag="VYO11_001042"
     CDS             8613..9461
                     /gene="pheA"
                     /locus_tag="VYO11_001042"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HEV1595629.1"
                     /translation="MKIAYLGPKGSFSHHVVQTAFPHEELQAFANITDVIKAYEQGLV
                     NYSVVPVENSIEGSVHETLDYLFHQAHIQAVAEIVQPIHQQLMVVPGHTKIEKIFSHP
                     QALAQGKKFIDEQYPEAQIEVTASTAYAARFISEHPDQPFAAVAPRSSAEEYGLELIA
                     EDIQEMEANFTRFWVLGAEKPSIPLQAQTEKMSLALTLPDNLPGALYKALSTFAWRGI
                     DLTKIESRPLKTALGEYFFIIDVDYTDKDLVHFAQKELEAIGIQYKILGAYPIYTISD
                     HGKERR"
     gene            9458..10732
                     /gene="psr"
                     /locus_tag="VYO11_001043"
     CDS             9458..10732
                     /gene="psr"
                     /locus_tag="VYO11_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyisoprenyl-teichoic acid--peptidoglycan
                     teichoic acid transferase Psr"
                     /protein_id="HEV1595630.1"
                     /translation="MSKENPLSHHEQLRYDYLLKNIHYLNEREKNEFAYLQEKLTLAR
                     GNSSSSLEQEREEQVDLPSYANRSRSQSKSQALSFPPKKKRRKLRLKRIFMVIFSLLV
                     CVALAMVFMFLRGYQDASAKKTADARAAQVEVFNGQDTRDGVNILIMGTDGRIGQNSV
                     ETRTDSIMVLNVGGSDKKMKLVSFMRDNLVYIDGYSQVINGRKQTDNKLNVAYELGEQ
                     EGQKGAEMVRQVLKDNFDLDIKYYALVDFQAFATAIDTLFPDGVTIDAQFSTLNGRPL
                     TEATVGDDLYATETESPTQTIKVGKQQMNGSTLLNYARFRDDDEADYGRTKRQQQVLT
                     AILEQIKDPTKLFTGSEALGKVFAMTSTNVPYTFLLTNGLSVLDGAKNGIEKLTIPEL
                     GDWVDAYDVYGGLGLLVDQNKYQTKLAQMGLR"
     gene            11011..11856
                     /locus_tag="VYO11_001044"
     CDS             11011..11856
                     /locus_tag="VYO11_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HEV1595631.1"
                     /translation="MNNMTDLKAIQARSLEMAEYFVAFCKEHDLLCYLCGGGAIGALR
                     NKGFIPWDDDLDFFMPRKDYEKLAELWPRYADERYFLSKSHKDFVDRNLFITIRDKKT
                     TCIKPYQQDLDLPHGLALDVLPLDYYPKNPAERKKQVRWALIYSLFCAQTIPEKHGAL
                     MKWGSCILLGLTPKSLRYRIWKKAEKEMTKYDLADCDGITELCSGPGYMRNKYPITSF
                     EDNLFLPFEGTEMPIPIGYDVYLRTAFGDYMTPPPADKQVPHHDAVIADMDKSYTEYK
                     GEYGG"
     gene            11846..12949
                     /locus_tag="VYO11_001045"
     CDS             11846..12949
                     /locus_tag="VYO11_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000225894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEV1595632.1"
                     /translation="MVAKKKILFFMWSFSLGGGAEKILSTIVSNLDPEKYDIDILEME
                     HFDKGYESVPKHVRILKSLQDYRQTRWLRAFLWRMRIYFPRLARRLLVKDDYDVEVSF
                     TIMNPPLLFSKRREVKKISWIHGSIEELLKDSSKRESHRSQLDAANTIVGISKKTSNS
                     IKEVYPDYTSKLQTIYNGYDFQTILEKSQEKIDIEIAPQSICTIGRIEENKGSDRVVE
                     VIRLLHQEGKNYHLYFIGAGDMEEELKKRVKEYGIEDYVHFLGYQKNPYQYLSQTKVL
                     LSMSKQEGFPGVYVEALSLGLPFISTDVGGAEELSQEGRFGQIIESNQEAAQAITNYM
                     TSASNFDVDEASQFIQQFTITKQIEQVEKLLEE"
     gene            12951..13937
                     /locus_tag="VYO11_001046"
     CDS             12951..13937
                     /locus_tag="VYO11_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000446977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV1595633.1"
                     /translation="METALISVIVPVYNVAQYLEKSIASIQKQTYQNLEIILVDDGAT
                     DESGRLCDSIAEQDDRVSVLHKKNEGLSQARNDGMKQAHGDYLIFIDSDDYIHPEMIQ
                     SLYEQLVQEDADVSSCGVMNVYANDESPQSANQDDYFVCDSQTFLKEYLIGEKIPGTI
                     CNKLIKRQIATDLSFPKGLIYEDAYYHFDLIKLAKKYVVNTKPYYYYFHRGDSITTKP
                     YAEKDLAYIDIYQKFYNEVVKNYPDLKEVAFFRLAYAHFFILDKMLLDDQYKQFEAYS
                     QIHRFLKGHAFAISRNPIFRKGRRISALALFINISLYRFLLLKNIEKSKKLH"
     gene            13953..15386
                     /locus_tag="VYO11_001047"
     CDS             13953..15386
                     /locus_tag="VYO11_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen polysaccharide polymerase Wzy family
                     protein"
                     /protein_id="HEV1595634.1"
                     /translation="MIDGKRLLFSLTIVSYALTLVSGVVYLFNNNNVSLLSTLLFLLV
                     SSLIACWNDIKYYLIHFIFYLTIFVFLVSRPTIDYFRDGALDTYHPIAYRFAFIVVMV
                     SILGLTTGGILARYFIARKKIKVANIGNSLKEVYIKRLRFVSLGVFLLTYPFYFIRLF
                     ERLLYRLQTSYYAYYANFESKLPYFTYILSTFTVYAMCMYLATKPKKLQATAVLVSFI
                     AANTIHLAIGTRNPFILSILFAFVYYFMREQTEKGKWIGFKEKLAIFVGSPILMLAMG
                     VLNYVRDNVQVSHTGFWDILLDFIYKQGTSFGVLARGFLFNSSLPYRDFRNFTFGPVL
                     DYFARGSLGAIFGGKAFEHTTNSVELAIDSNSYAHNLSYLVLNKEYLKGHGIGSSYIM
                     ELYTDYGMIGVFLLSFLLGVLFIAMLQVAYRSRTILFALSLLILNNLFFMPRSSFSES
                     FFNLFTMQFWGIVLVIIFVAKMLTKEN"
     gene            15415..16449
                     /locus_tag="VYO11_001048"
     CDS             15415..16449
                     /locus_tag="VYO11_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HEV1595635.1"
                     /translation="MFEHYSVADLFANLYKKRKANILALIALFALIAVPFTIKAVRNK
                     NTVKDTTSYSTYLIYKITPPKESAKTILNHQIGGYSDFYGKLIDGNLNGAYLFNDVEP
                     SELKKIASELDTTETTLKNSTNDYWWKKLTVYYMIDDAGVGVKILTSSKDANDLLEKK
                     IDGLIEKFKHAYANVKIEKLETINSKELNANGETALGLNVKNLILRLVVIGVVCVILV
                     VMGNVLVYLFNPTINRVGDFSQYQIDFVTEITTIANLADVLSYKNTGQELTIVSSNKA
                     ILDKLKQSQEALKGMHFVDLQDVSSLLERDTVLLVEEYGVTRYKKFEQSLQILRNLNR
                     SILGVATFKL"
     gene            16649..17386
                     /gene="mecA"
                     /locus_tag="VYO11_001049"
     CDS             16649..17386
                     /gene="mecA"
                     /locus_tag="VYO11_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HEV1595636.1"
                     /translation="MKMKQISDTTLKITMSLEDLMDRGMEIADFLVPQEKTEEFFYAI
                     LDELEMPDSFLDTGMLSFRVTPKPDKVDVFVTKSKIDQNLDFEDLSDLPDMEELAQMS
                     PDEFIKTLEKSIADKTKDDIEAIQSLEQVEAKEEEQEQAEQEAESKKEPYIYYILSFA
                     KLADLVVFAKTVTFEMETSELYKMNERYYLTILVDIENHPSPYPAWLLARMREFADDS
                     DISRSVLQEYGQVLMSHDAVLNLQKIG"
     gene            17537..18823
                     /locus_tag="VYO11_001050"
     CDS             17537..18823
                     /locus_tag="VYO11_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HEV1595637.1"
                     /translation="MTVKIALLGFGTVASGVPFLLKENGGKINQSAHSDIKVAKVLVK
                     DEDEKNRLLAAGNDFNFVTNVDDILSDQDITIVVELMGRIEPAKTFITRALEAGKHVV
                     TANKDLLAVHGAELLEIAQANKVALYYEAAVAGGIPILRTLANSLASDKITRVLGVVN
                     GTSNFMVTKMVEEGWSYDDALAEAQRLGFAESDPTNDVDGIDAAYKMVILSQFAFGMK
                     IAFDDVAHKGIRNITPEDVAVAQELGYVVKLVGSIEETSSGIAAEVTPTFLPKAHPLA
                     SVNGVMNAVFVESIGIGESMYYGPGAGQKPTATSVVADIVRIVRRLNDGTIGKDFNEY
                     SRDLVLANPEDVKANYYFSILALDSKGQVLKLAEIFNAQDISFKQILQDGKEGDKARV
                     VIITHKINKAQLENVSAELKKVSEFDLLNTFKVLGE"
     gene            18825..19694
                     /locus_tag="VYO11_001051"
     CDS             18825..19694
                     /locus_tag="VYO11_001051"
                     /EC_number="2.7.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000692406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine kinase"
                     /protein_id="HEV1595638.1"
                     /translation="MKIIVPATSANIGPGFDSVGVAVTKYLQIEVCEERDEWLIEHQI
                     GKWIPHDERNLLLKIALQIVPDLQPRRLKMTSDVPLARGLGSSSSVIVAGIELANQLG
                     QLNLSDHEKLQLATKIEGHPDNVAPAIYGNLVIASSVEGQVSAIVADFPECDFLAYIP
                     NYELRTRDSRSVLPKKLSYKEAVAASSIANVAVAALLAGDMVTAGQAIEGDLFHERYR
                     QDLVREFAMIKQVTKENGAYATYLSGAGPTVMVLASHDKMPTIKAELEKQPFKGKLHD
                     LRVDTQGVRVEAK"
     gene            19770..19847
                     /locus_tag="VYO11_001052"
                     /pseudo
     CDS             19770..19847
                     /locus_tag="VYO11_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            20034..20972
                     /gene="msrB"
                     /locus_tag="VYO11_001053"
     CDS             20034..20972
                     /gene="msrB"
                     /locus_tag="VYO11_001053"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HEV1595639.1"
                     /translation="MAEIYLAGGCFWGLEEYFSRISGVLETSVGYANGQVETTNYQLI
                     KETDHAETVQVIYDEKEVSLREILLYYFRVIDPLSINQQGNDRGRQYRTGIYYQDEAD
                     LPAIYTVVQEQERMLGRKIAVEVEQLRHYILAEDYHQDYLRKNPSGYCHIDVTDADKP
                     LIDAANYEKPSQEVLKASLSEESYRVTQEAATEAPFTNAYDQTFEEGIYVDITTGEPL
                     FFAKDKFASGCGWPSFSRPISKELIHYYKDLSHGMERIEVRSRSGSAHLGHVFTDGPR
                     ELGGLRYCINSASLRFVAKDEMEKAGYGYLLPYLNK"
     gene            21030..22754
                     /locus_tag="VYO11_001054"
     CDS             21030..22754
                     /locus_tag="VYO11_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1595640.1"
                     /translation="MKHLLSYFKPYIKESILAPLFKLLEAVFELLVPMVIAGIVDQSL
                     PQGDQGHLWMQIGLLLIFAVIGVLVALIAQFYSAKAAVGFAKELTNDLYRHILSLPKD
                     SRDRLTTSSLVTRLTSDTYQIQTGINQFLRLFLRAPIIVFGAIFMAYRISAELTFWFL
                     VLVAILTIVIVGLSRLVNPFYSSLRKKTDQLVQETRQQLQGMRVIRAFGQEKRELQIF
                     QTLNQVYARLQEKTGFWSSLLTPLTYLIVNGTLLVIIWQGYISIQGGVLSQGALIALI
                     NYLLQILVELVKLAMLINSLNQSYISVKRIEEVFVEAPEDIHSELEQKQATRDKVLQV
                     QELTFTYPDAAQPSLRYISFDMTQGQILGIIGGTGSGKSSLVQLLLGLYPVDKGNIDL
                     YQNGRSPLNLEQWRSWIAYVPQKVELFKGTIRSNLTLGFNQEVSDQELWQALEIAQAK
                     DFVSEKEGLLDALVEAGGRNFSGGQKQRLSIARAVLRQAPFLILDDATSALDTITESK
                     LLKAIRENFPNTSLILISQRTSTLQMADQILLLEKGELLAVGKHDDLMKSSQVYCEIN
                     ASQHGKED"
     gene            22756..24507
                     /locus_tag="VYO11_001055"
     CDS             22756..24507
                     /locus_tag="VYO11_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1595641.1"
                     /translation="MKRQTVNQTLKRLAVDLASHPFLLFLAFLGTIAQVGLSIYLPIL
                     IGQVIDQVLVAGSSPVFWQIFLQMLLVVIGNTLVQWANPLLYNRLIFSYTRDLRERII
                     HKLHRLPIAFVDRQGSGEMVSRVTTDIEQLATGLTMIFNQFFIGVLMILVSILAMLQI
                     HLLMTLLVLLLTPLSMVISRFIAKKSYHLFQKQTETRGIQTQLIEESLSQQTIIQSFN
                     AQTEFIQRLREAHDNYSGYSQSAIFYSSTVNPSTRFVNALIYALLAGVGAYRIMMGSA
                     LTVGRLVTFLNYVQQYTKPFNDISSVLAELQSALACVERIYGVLDSPEVAETGKEVLT
                     TSDQVKGAISFKHVSFGYHPEKILIKDLSIDIPAGSKVAIVGPTGAGKSTLINLLMRF
                     YPISSGDILLDGQSIYDYTRVSLRQQFGMVLQETWLTQGTIHDNIAFGNPEASREQVI
                     AAAKAANADFFIQQLPQGYDTKLENAGESLSVGQAQLLTIARVFLAIPKILILDEATS
                     SIDTRTEVLVQDAFAKLMKGRTSFIIAHRLSTIQDADLILVLVDGDIVEYGNHQELMD
                     RKGKYYQMQKAAAFSSE"
     gene            24899..26158
                     /locus_tag="VYO11_001056"
     CDS             24899..26158
                     /locus_tag="VYO11_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRZ/ATZ family protein"
                     /protein_id="HEV1595642.1"
                     /translation="MKVFQHVNIVTCDQDFHVYLDGILAVKDSQIVYVGQDKPAFLEQ
                     AEQIIDYQGAWIMPGLVNCHIHSAMTGLRGIRDDSNLHEWLNDYIWPAESEFTPDMTT
                     NAVKEALTEMLQSGTTTFNDMYNPNGVDIQQIYQVVKTSKMRCYFSPTLFSSETETTA
                     ETISRTRSIIDEILKYKNPNFKVMVAPHSPYSCSRDLLEASLEMAKELNIPLHVHVAE
                     TKEESGIILKRYGKRPLAFLEELGYLDHPSVFAHGVELNEREIERLASSQVAIAHNPI
                     SNLKLASGIAPIIQLQKAGVAVGIATDSVASNNNLDMFEEGRTAALLQKMKSGDASQF
                     PIETALKVLTIEGAKVLGMENQIGSLEVGKQADFLVIQPQGKIHLQPQENMLSHLVYA
                     VKSSDVDDVYIAGEQVVKQGQVLTVEL"
     misc_feature    26234..26369
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            26408..26908
                     /locus_tag="VYO11_001057"
     CDS             26408..26908
                     /locus_tag="VYO11_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001287276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HEV1595643.1"
                     /translation="MSEAIIAKKAELVDVVAEKMKAAASIVVVDARGLTVEQDTVLRR
                     ELRGSEVEYKVIKNSILRRAAEKAGLEDLASVFVGPSAVAFSNEDVIAPAKILNDFSK
                     NAEALEIKGGAIEGAVASKEEILALATLPNREGLLSMLLSVLQAPVRNVALAVKAVAE
                     SKEDAA"
     gene            26984..27352
                     /gene="rplL"
                     /locus_tag="VYO11_001058"
     CDS             26984..27352
                     /gene="rplL"
                     /locus_tag="VYO11_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HEV1595644.1"
                     /translation="MALNIENIIAEIKEASILELNDLVKAIEEEFGVTAAAPVAVAAA
                     DAADAGAAKDSFDVELTSAGDKKVGVIKVVREITGLGLKEAKELVDGAPALVKEGVAT
                     AEAEEIKAKLEEAGASVTLK"
     gene            27539..27709
                     /locus_tag="VYO11_001059"
     CDS             27539..27709
                     /locus_tag="VYO11_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001168336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1595645.1"
                     /translation="MQKEGQSSRQFVKSHLMTIMGVDIVKATQLVDEMEQVGLIRFDE
                     FGNVGILVLEGQ"
     gene            27709..27960
                     /locus_tag="VYO11_001060"
                     /pseudo
     CDS             27709..27960
                     /locus_tag="VYO11_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648301.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
     gene            27971..28294
                     /locus_tag="VYO11_001061"
     CDS             27971..28294
                     /locus_tag="VYO11_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1595646.1"
                     /translation="MTFLDDYHKKHNYPLFYESYLQNVMEFLESQDIKNGVDAFVDDH
                     QNLVFVLYGQGYRAEGKEGILTTQVTVKAYDEDKKPINFANLLDSLIVSEYQMEPNLW
                     KVSHD"
     gene            28287..28667
                     /locus_tag="VYO11_001062"
     CDS             28287..28667
                     /locus_tag="VYO11_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1595647.1"
                     /translation="MIDLYLSKNSQRNQLLLDFFQKYGIEVTPHSISEMTKDKLIEMM
                     SYSSDCFEFLSPNLLRFKNRDNLRLTDFIEMILKNPELCIRLPLAVSNKRVYPNLNLE
                     EARALLPRDTKQLIYMAQTHYLSS"
     gene            28680..28913
                     /locus_tag="VYO11_001063"
     CDS             28680..28913
                     /locus_tag="VYO11_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEV1595648.1"
                     /translation="MAERFWENLSIILAERNISWIELTRKMFAGEFHYPSELNRLYQK
                     IRHYKMEQRMPQSPWVERIVQVLDLDYEDLFRR"
     gene            28916..29503
                     /locus_tag="VYO11_001064"
     CDS             28916..29503
                     /locus_tag="VYO11_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000821297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV1595649.1"
                     /translation="MKRIIPVYIFQQVNVLLVSLYLLKLLCIGELTILQILYCASLIS
                     FLWMYGQRKQVVKVNMKTRMKWLGIGFVSLLIISLCFSLIHAQGTTNQANLIGLQHQV
                     PWFSFLLFLINASMVEEFLYREILWNLVRKLDIRVALTSVLFALVHHPGTILAWCLYV
                     SLGIFLGMVRYKSDLWGSMGLHLVWSLLVYSLLLF"
     gene            29705..29842
                     /locus_tag="VYO11_001065"
     CDS             29705..29842
                     /locus_tag="VYO11_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004264816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SapB/AmfS family lantipeptide"
                     /protein_id="HEV1595650.1"
                     /translation="MAEEVLNLQLVSVQVDETDEVDGMRFSTFSTNRCGNWSAFSWEN
                     C"
     gene            30098..30331
                     /locus_tag="VYO11_001066"
     CDS             30098..30331
                     /locus_tag="VYO11_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEV1595651.1"
                     /translation="MAERFWENLSIILAERNISWIELTRKMFAGEFHYPSELNRLYQK
                     IRHYKMEQRMPQSPWVERIVQILDLDYEDLFRR"
     gene            30334..30921
                     /locus_tag="VYO11_001067"
     CDS             30334..30921
                     /locus_tag="VYO11_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000821297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV1595652.1"
                     /translation="MKRIIPVYIFQQVNVLLVSLYLLKFLCIGELTILQVLYGASLFS
                     FLWMYGQRKQVVKVNMKTRMKCLGIGLASLLIISLCFSLIHAQGSTNQTNLIGLQHQV
                     PWFSFLLFLINASMVEEFLYREILWNLVRKLDIRVALTSVLFALVHHPGTILAWCLYV
                     SLGMFLGMVRYKSDLWGSMGLHLVWNFLVYSLLLF"
BASE COUNT         9213 a         5617 c         6927 g         9201 t
ORIGIN      
        1 ttgagtttgt aacaaaaggc ttctctataa aatcaaattt tccagatatc tactgaagct
       61 gatttatttc ttcatctttc ttctactacc tttgtcacta aatttgacag acacatattg
      121 ctgatacaac ctctctacct ataatctcac ggttaacctg aggctagttt catagtttgc
      181 tatttgattt tcgttgataa aaagaaatgc tcctccaaga cggaagagca ttttttactg
      241 tgattcttac acatttactt cctagttttg caggaagtct agtataccat tttttaaaag
      301 aagagtaaaa aagcaagggt agtttctttt ttgagaattg tctaaaagtt tgatataatg
      361 gtagttatga atagaataag agtcagcaaa agggttgaaa agaagcttgc taaggggcta
      421 gttttactag aagccagtga tcttgagaat gtcaatctta aggatcagga agtagaggtg
      481 cagggtcagg aaggaaactt tcttgggact gcctaccttt ctcagcaaaa caagggcttg
      541 ggctggttta tcagcaaaga caaggtggcc ttcaatcaag ctttctttga aacgttgttt
      601 agaaaagcca aagaaaagag aaacgcctac tatcaagatg atttgacaac tgcctatcgt
      661 ctctttaatc aagagggaga tggctttggg ggtctgacag tggaccttta tggcgactac
      721 gccgtctttt cttggtataa ctcttatgtt tatcagattc gtcagactat atcagaagcc
      781 tttagacagg ttttccctga ggttttagga gcttatgaga aaatccgctt taagggtttg
      841 gactatgaat ctgcccatgt ttatggtcaa gaagcacctg actttttcac tgttttagaa
      901 aatggtgtcc tgtatcaagt ctttatgaat gatggcttga tgacaggaat tttcctagac
      961 cagcatgagg ttcgcggtag tttagttgac ggcttttcta tgggtaaatc cttgctcaat
     1021 atgttttcct acacagcggc tttttcagta gctgcggcca tgggaggagc tagccagaca
     1081 acttctgttg atctagccaa acgttcacga gaattgtctc aagcgcattt tcaggcaaat
     1141 gggctcagca cagacgagca tcgttttata gtcatggatg tctttgagta tttcaaatat
     1201 gccaaacgca aagacttgac ctacgatgtg attgtcctag atccgcctag ctttgctcgg
     1261 aataaaaaac aaactttctc tgtggccaag gattatcaca agttgatttc ccagagtctt
     1321 gagattttaa atccgggagg gattatcatt gccagtacca atgctgccaa tgtttcccgt
     1381 cagaaattta cagaacaaat tgataaaggt tttgcaggaa gaagttacca gattttaaac
     1441 aaatatggtc ttccagcaga ttttgcctat aataaaaaag atgaaagtag taattacctc
     1501 aaggtgatta gtatgaaggt tagtaaatga aattaatcgt ttcagtaatg ccaagaagtt
     1561 tagaggaggc tcaggctctg gatgccacga ggtacctgga tgccgacatc attgaatggc
     1621 gtgccgacta tctgcctaaa gaagcgattt tgcaggtagc tccagccatt tttgaaaaat
     1681 tcgcaggccg tgagttggtt ttcacgctac gaactcgctc cgaaggtgga gaaatcgacc
     1741 tttctccaga agagtatatc catctaatca aggaagttgc gcaactctat caaccagact
     1801 atattgattt tgagtactat agctacaagg atgtttttga ggaaatgctg gacttcccaa
     1861 atcttgtttt gagttaccat aatttccaag aaacacctga gaacatgatg gaaatcttgt
     1921 cagagttgac gatcctaaat ccaaaacttg ttaaggttgc ggtgatggct cacacggagc
     1981 aggatgtctt agacttgatg aactatacac gaggctttaa aaccctcaat cctgaacagg
     2041 aatatgtgac catttctatg ggtaaggtgg gcaaggtctc tcgtatcact gcggatgtga
     2101 ctggttcgag ttggtctttt gccagtctgg atgaggttag tgcccctggg cagatttctc
     2161 tagctagcat gaaaaaaatc agggagattt tggatgaagc ttgatggcta tacacgttta
     2221 actgcagttg ttgccaatcc tattaagcat tctatttctc ccttcatcca caatagagcc
     2281 tttgaggcga cagctaccaa cggtgcttat gtggcttggg agattgaagc gagtgacttg
     2341 gcagaaacag tggccaatat tcgtcgctac cagatgtttg gcatcaatct gtccatgccc
     2401 tataaggagc aggtgattcc ttatttggat aagctgagcg atgaagcgca cttgattggt
     2461 gcggttaata cggttgtcaa tgagaatggc aatttaattg gatataatac agatggcaag
     2521 ggatttttta agtgcttgcc ttcttttaca atttcaggta aaaagatgac cctgctgggt
     2581 gcaggtggtg cggctaaatc aatcttggca caggctattt tggatggcgt cagtcagatt
     2641 tcggtctttg ttcgttccgt ttctatggaa aaaacaagac cttacctaga caagttacag
     2701 gagcagacag gttttaaagt ggatttgtgt gctttagaat atgtttctga actgcaagca
     2761 aggattgccg agtcggattt gctagttaat gccaccagtg tgggcatgga tggccaatcc
     2821 tctcctgttc ctgaaaacat agtcttacca gaaactctct tagttgcaga tatcatatac
     2881 caaccctttg aaacaccgtt tttgaaatgg gctagaagtc agggcaatcc agcagtcaat
     2941 ggtctgggaa tgttgctcta tcaagctgca gaagcttttc aactgtggac aggcaaggaa
     3001 atgccgacag aagagatttg gcagtcttta acagaaaaat accaataaag aaagggagac
     3061 tctcctatga aaatcagaat cgatattcct catcatcctt atgatattca gattgaaaaa
     3121 ggttgtatgg cccaggctgg tcagtggttg cgagaactct ggcaaccgca aaaggtagtc
     3181 attgtgacag ataaccatgt agcctctctc tatgcagaga aggtcaagct cagcctagaa
     3241 gatgctggtt ttcaggtagc tgtttttgat ttcttagaag gtgaagaaag aaagaattta
     3301 actactgttc agaaagtcta tgaatttcta gtcaagcaag gtctgactcg tagcgatgga
     3361 atcgttgctc ttggtggtgg cgttgttggg gacctggctg gatttgtagc ctctacctat
     3421 atgcggggta ttcactttgt tcagattccg actagtttga cagctcaggt tgattcttct
     3481 atcggtggaa agacaggcgt taacacacca tttgctaaaa atatggtggg gacctttgcc
     3541 caaccagatg gggttctgat tgatccactt gttcttgaaa ccctcggaaa aagagagttg
     3601 attgaaggga tgggtgaagt tatcaagtat ggcttgattg aggatccaga actgtgggct
     3661 ctcttgacgg gactgaatgg ttctgttgag agtattttgg aacatgcaga gaccttgatt
     3721 gaacattctt gtcaggtgaa gcgcaagatg gtggttgaag atgagttgga caatggtatt
     3781 cgtctttacc tcaattttgg ccacactatt ggccatgcca tcgaagcgac tgccggttat
     3841 ggcaaggtca tgcatggaga ggctgttgcc atgggaatgg tacagatttc caaggttgct
     3901 gaggaaaaag gcctcatgcc agctggcatt acccaatcta tcacagagat gtgtcagaaa
     3961 ttcggcttgc ctgttgacta tgaaaattgg aaagttgaca agctttatca ggctcttact
     4021 catgacaaga aagcgcgtgg taacaccttg aaattggtct tggtgccaga gcttggttca
     4081 gcgaccattc atccagtttc tctggaagag atgaaagact acttggtaaa ataaggagag
     4141 tgtatgagat atttaactgc aggagaatca cacggccccc gtctaacagc tattattgag
     4201 ggaattccag ctggacttcc attgacagct gaggatatca atgaggacct tagacgccgt
     4261 cagggtggct acggtcgtgg tggtcgtatg aagattgaga atgaccaggt tgtctttact
     4321 tcgggcgttc gccacgggaa gacgacaggg gcgcctatta ctatggatgt catcaataag
     4381 gaccaccaga aatggctgga catcatgtct gcggaggaca ttgaagaccg tcttaaaagc
     4441 aagcggaaaa ttactcatcc tcgcccaggt catgccgatt tggttggggg gattaagtac
     4501 cgttttgatg atttgcgaaa ttctttggag cgttcatcag ctcgtgaaac caccatgcgg
     4561 gtggcagttg gtgcagtagc caaacgcctc ttggctgagc tggatatgga gattgccaac
     4621 catgtcgtgg tctttggtgg caaggaaatc gatgttcctg aaaatctgac agtcgctgaa
     4681 attaagcaaa gagctgccca gtctgaagtt tctattgtca accaagaacg agaacaggaa
     4741 atcaaggact atattgacca aatcaaacgt gatggtgata ccatcggtgg ggttgtggag
     4801 acagtcgtag gaggcgttcc agttggtctt ggttcctatg tccaatggga tagaaaattg
     4861 gatgcaagat tggctcaagc tgttgtctct atcaatgcct ttaaaggggt ggaatttggt
     4921 cttggctttg aggctggtta tcgtaaaggc agccaagtta tggatgaaat tctctggtct
     4981 aaagaagacg gttatactcg ccgtaccaat aatctaggtg gttttgaagg tggtatgact
     5041 aatgggcaac ccatcgttgt tcgtggggtc atgaaaccca ttcctactct ttataaacct
     5101 cttatgagtg tggatatcga aacccacgaa ccttacaagg caaccgtgga gagaagtgat
     5161 ccgactgctc ttccagctgc aggaatggtc atggaagcag ttgtagcaac ggttctggcg
     5221 caagaaatcc tcgaaaaatt ctcatcagat aatcttgagg aactaaaaga agcggtagcc
     5281 aaacaccgag actatacaaa gaactattaa ggagttccta tggcaaaaac aatctatatc
     5341 gcaggtcttg ggttgattgg agcctctatg gcacttggta tcaaacgcga tcatccagat
     5401 tatgaaattt taggttataa tcgtagtcaa gcttcgagag atatcgcctt gaaagaaggc
     5461 atgattgacc gtgcaacgga tgattttgct agttttgctc ctttggcaga tgtcattata
     5521 ctcagcttgc caatcaaaca aactattgct ttcattaagg agttggccaa tttggatttg
     5581 cgagaaggcg ttattatttc agatgctggt tcgaccaagt caaccattgt ggatgcggcg
     5641 gagcagtatt tggctggcaa gtctgttcgc tttgtcgggg cccatcccat ggctggtagt
     5701 cacaagacag gggctgcttc ggcagatgtc aatctttttg aaaatgccta ttatatcttt
     5761 acaccttcaa gcctgacaag tcaggacacg cttaaggaaa tgaaggatct gctttcaggt
     5821 cttcatgctc gttttatcga gattgatgcc aaggagcatg atcgtgtcac ttctcagatt
     5881 agccattttc ctcatatttt ggcttctagt ctcatggagc agactgcggt ctatgctcaa
     5941 gagcatgaga tggcaaggcg ctttgcggca ggtggttttc gagatatgac ccgaattgcg
     6001 gaaagcgagc caggaatgtg gacctccatt ctcttgtcca atagcgagac cattctggat
     6061 agaattgagg atttcaagga acgtttggaa gcgattggtc aggccattag taagggagat
     6121 gaagagcaaa tttggaactt ttttaaccaa gcgcgtgaac aacgccagac catggaaatc
     6181 cataagcgtg gtggtgtgga tagctcttac gacctctatg ttgacgttcc tgatgaagaa
     6241 gatgtcatcc tgcggatttt ggaactgcta cgtggaactt ccttggttaa catccacatc
     6301 aacgaggaaa atcgtgagga tattcacgga atcctacaaa tttcatttaa aaatgctcaa
     6361 gacttggaaa gagctgagca tctcataaca gaaaataccg actatacagt cgtcatcaaa
     6421 taaggagaag aacatgtcaa atatttacga tagtgcaaac gaactcagtc gcggtctacg
     6481 cggattacca gaatacaagg ctgttaaagc agctaaagat gcgattgcag cagatgctga
     6541 ggcaagcaaa atctttacag aatatcttgc ctttcaagag gaaattcaaa aactagcaca
     6601 gacaggtcaa atgccagatg cgtccttcca agctaagatg gaaggctttg gtaaacagat
     6661 tcaaggaaat agcctcttgt cagaattctt taccaagcaa caacaattgg ccatttacct
     6721 ttctgacatt gaaaaaattg ttttcgaacc agtttcagaa ttgctgaaat aagaaaagaa
     6781 ctatcctaaa gtcaggaatt tttaaggaat ttctggcttt ttatgataaa ataggtaaaa
     6841 gtattgcaag tatgaggtcc agtatgaaac taaaaacaaa tattcgccat ttacatggta
     6901 gtatccgcgt cccaggtgac aagtctatca gccaccgttc cattatcttt ggaagtttgg
     6961 ctgagggtga gaccaaggtt tatgatattc tgcgaggtga agacgttctt tcgaccatgc
     7021 aggtttttcg tgaccttggt gttgaaattg aggataaaga tggggttatt accattcaag
     7081 gtgtaggcat ggctggctta aaagcgccgc aaaatgccct taatatggga aattctggca
     7141 cctcgattcg cctgatttca ggtgtccttg ctggtgcaga tttcgaagta gagatgtttg
     7201 gagatgatag tctttccaaa cgtcctatgg accgtgtgac ccttccactg aaaaaaatgg
     7261 gcgtcagcat ctcagggcaa actgaacgag acttgcctcc ccttcgctta aaagggacga
     7321 aaaacctaag acctattcat tatgagttgc caattgcctc tgcccaagtc aagtcagcct
     7381 tgatgtttgc agccttacaa gctaaggggg agtcagttat tatcgaaaaa gagtgcaccc
     7441 gtaatcatac tgaagatatg ttgcaacaat ttggtggtca tttaagtgtg gacggtaaga
     7501 aaatcacagt ccaagggcca caaaaattga caggacagaa ggtggtcgta ccaggagata
     7561 tttccagtgc agccttttgg ttagtcgcag gtttgattaa tccaaattct catctagtgc
     7621 tgcagaatgt gggaatcaac gaaacgcgta ctggtattat tgatgtcatt cgtgccatgg
     7681 gtggaaaatt agaagttact gaaatcgatc cagtcgctaa atcttctacc ttgactgttg
     7741 agtcttctga cttgaaagga acagaaattg gtggcgcttt gattccacga ttgattgatg
     7801 aattgcccat tattgccctg cttgcgaccc aagcccaagg tgtaacagtt atcaaggatg
     7861 ctgaggagct caaggtcaag gaaacagacc gtattcaggt tgtggcagac gccttaaata
     7921 gtatgggagc agatattact cctacggcag atgggatgat tatcaaaggg aaatcagctc
     7981 ttcacggtgc tagagtcaat acgtttggtg accaccgtat cggcatgatg acagctatcg
     8041 cagccctctt ggttgcagat ggagaggtgg atcttgaccg tgcagaagcc atcaatacca
     8101 gctatcctag tttctttgat gatttggaga gcttgattca tggctaaggt gttattaggg
     8161 tttatggggg ctggaaaatc gactattgca agaggcttgg accctaatta ccttgatatg
     8221 gatgctctga ttgagaatcg cctaggtatg tccattgcga attttttcgc tgaaaaggga
     8281 gaaacagcct ttcgtcaggt agaatcagaa gtcctagctg atttactaca aacagaccaa
     8341 gtcgtgtcaa ctggaggagg agtggttatt tctcagagaa atcgtgactt actcaagact
     8401 aatacagata acatatacct gaaagcagat tttgaaaccc tctacctacg tatcgcagct
     8461 gataaggaca atcagcgacc gctttttcta aataatagca aggaagaact agtagctatt
     8521 tttcaagaaa gacaggcttg gtatgaggaa gtggctagtc gggttttgga tgtgaccaag
     8581 ctaagcccag aggaaattat agaggaacta agatgaaaat agcttatcta ggtcccaagg
     8641 gatcattttc acaccacgtt gtgcagacag cttttcctca tgaggaattg caggcttttg
     8701 ccaacattac agatgtcatc aaggcttatg agcaaggatt agtgaactat tctgtggtgc
     8761 cagttgaaaa ttctattgag ggtagtgttc atgaaacctt ggactatctt tttcatcagg
     8821 ctcacatcca agcagtagca gaaatcgttc agcctattca tcagcagttg atggtggttc
     8881 caggccatac taagattgaa aagatttttt cacatccaca ggccttggct caaggaaaga
     8941 aattcatcga tgaacaatat ccagaggctc aaatcgaggt aacagctagt acagcttatg
     9001 cggcccgttt tatttccgaa catccagacc agccctttgc agcagttgca cctagaagtt
     9061 ctgctgaaga atatggattg gaactgattg ccgaggatat tcaggaaatg gaagccaatt
     9121 tcacacgttt ctgggttcta ggagctgaaa agcctagtat tcccttgcaa gcacaaactg
     9181 aaaagatgag tttggccttg acattacctg acaaccttcc aggtgcactt tataaggccc
     9241 tgtcgacctt tgcttggcga ggaattgact tgacaaaaat tgaaagtcgt ccactcaaga
     9301 cagcactggg tgaatacttt ttcattatcg atgtggatta taccgataag gacttggtcc
     9361 actttgccca aaaagaatta gaagcgattg gaatccagta taaaattctg ggtgcctatc
     9421 ctatttatac aatatcagac catggaaagg agagaagatg agtaaagaaa atcccttaag
     9481 tcatcatgag cagttgcgtt atgattattt gctaaaaaat attcactacc tcaatgagag
     9541 agaaaaaaat gagtttgcct atttgcaaga aaagctaact cttgctaggg gaaatagtag
     9601 ctctagcttg gaacaagaaa gagaagagca ggttgactta ccaagctatg cgaaccggag
     9661 tcgctcacaa tccaaatcac aagcactctc tttccctcca aaaaagaaaa gacggaagct
     9721 ccgtcttaaa cgaattttta tggtgatttt ttcacttttg gtctgtgtgg ctttggccat
     9781 ggtattcatg tttttgcgtg gttaccaaga tgctagcgca aagaaaactg ctgatgcccg
     9841 ggcagctcaa gtagaagtct ttaatggtca ggacactaga gatggagtta atattttaat
     9901 catgggtact gatggtcgaa tcggccagaa cagtgttgag acacgaactg actctattat
     9961 ggtattaaat gtcgggggct cagataagaa aatgaagcta gtcagtttca tgcgtgataa
    10021 tttggtctat atagatggtt atagtcaagt gattaatggt agaaaacaga cagataacaa
    10081 gttaaacgta gcctacgagt taggagaaca agaggggcaa aaaggggcag aaatggttcg
    10141 ccaagtcttg aaagataatt ttgacttgga cattaagtac tacgccttgg ttgatttcca
    10201 ggcctttgcc acagcgattg acacgctttt ccctgatggg gtgacgattg atgctcaatt
    10261 ttcaacattg aatgggcgtc ccctaacaga agctacagtc ggagatgatt tatacgctac
    10321 cgagactgag tctccaaccc aaaccattaa agtcggaaaa cagcagatga atggctcgac
    10381 cctgctcaat tatgctcgtt tccgtgatga tgatgaggcg gattacggcc gtacaaaaag
    10441 acagcaacaa gttttaacag caattttaga gcaaattaaa gatcccacta aacttttcac
    10501 tggttctgaa gctcttggaa aggtttttgc tatgacctca accaacgtac cttatacttt
    10561 cctcctaaca aacggtttat ctgttttgga tggagcaaaa aatggtattg aaaaattgac
    10621 gattccagaa ctgggtgact gggtagatgc ctatgatgtt tatggaggct tgggcttgct
    10681 ggttgatcaa aacaaatatc aaaccaagct cgctcaaatg ggcttgagat aagataatac
    10741 tcaatgaaaa tcaaagtgca aactaggaag ctagccgcag gctgctaaaa acacagtttt
    10801 gaggttgtag ataagactga cgaagtcagt tacctatacc tacggcaagg tgaagctgac
    10861 gtggtttgaa gagattttcg aagagtataa gacagaaaaa tcaaagtttg atagctattt
    10921 ggatagcagt caggctttga ttttttacag tctgcaatag attttcaccc cttgtttgtg
    10981 gtataatgaa acgatacgat agaaagaata atgaacaata tgactgattt aaaagcaatt
    11041 caggctcgta gtctggagat ggctgaatat tttgtggcct tttgtaaaga acatgatttg
    11101 ctctgttatc tctgtggcgg aggcgctatt ggtgcccttc gaaacaaggg atttattcct
    11161 tgggacgacg acctagactt ttttatgcct cgtaaagatt atgagaaatt agcagaatta
    11221 tggcctcgtt atgcagatga acgttatttc ttgtcaaaga gtcacaagga ttttgttgat
    11281 cgtaatcttt ttattaccat tcgtgacaag aaaaccacct gtatcaagcc ttatcagcag
    11341 gatttggatt tgccacatgg tctggccttg gatgttttgc ctttggatta ttatccgaaa
    11401 aatccagctg agcggaaaaa acaggttcgt tgggccttga tttattcact cttttgtgcg
    11461 caaactattc cagaaaagca tggtgctctc atgaaatggg gaagttgcat tttactgggt
    11521 ttgactccaa aatctctccg ttatcgcatc tggaaaaaag ctgagaaaga aatgactaag
    11581 tatgatttgg ctgattgtga tggcattaca gaattatgct caggtcctgg ctacatgaga
    11641 aacaagtacc caatcacatc ttttgaagac aatcttttct tgccatttga aggaacagag
    11701 atgcctattc caatcggcta tgatgtctat ctcagaactg cttttgggga ttatatgacg
    11761 cctccaccag cagacaagca ggtaccgcat catgatgctg tcatcgctga tatggataag
    11821 tcttatacag aatacaaggg agaatatggt ggctaagaaa aaaatcttat tttttatgtg
    11881 gtctttttct cttggaggtg gtgcagagaa gattctatca actattgttt caaatctgga
    11941 tccagaaaag tatgatattg atattcttga aatggagcac tttgacaagg gatatgaatc
    12001 tgttccaaag catgtacgca ttttaaaatc ccttcaagat tatcgccaaa ccagatggtt
    12061 acgagctttt ttgtggagaa tgagaattta ttttccaaga ctggctcgtc gtttgcttgt
    12121 aaaagatgat tatgatgttg aagtttcttt taccattatg aatccaccac tgttgttctc
    12181 taaaagaaga gaagtcaaga agatatcttg gattcatgga agtattgaag aacttcttaa
    12241 ggatagctct aaaagagaat cacatagaag ccagttggat gctgcgaata caattgtagg
    12301 gatttcaaaa aagaccagca attctatcaa ggaagtttat ccagattata cttctaaatt
    12361 acagacaatc tacaatggat atgattttca gactattcta gaaaaatctc aagagaagat
    12421 cgatatcgag attgctcctc aaagtatctg tactatcgga cggattgagg aaaataaggg
    12481 ttctgaccgt gtagtggaag tgatacgatt attacaccaa gagggaaaaa actatcatct
    12541 ctattttatc ggggctggtg atatggaaga ggaactgaaa aaacgagtca aagagtatgg
    12601 gattgaggac tatgtacatt tccttggtta tcaaaaaaat ccttatcagt atttatctca
    12661 gacgaaagtt ctcttgtcta tgtctaaaca agaaggtttt cctggagtgt atgtggaggc
    12721 cttgagtctg ggactccctt ttatctctac ggacgttgga ggggctgagg aattatccca
    12781 agaaggacga tttggacaaa tcattgagag caatcaagag gcagctcagg cgattactaa
    12841 ttacatgact tctgcctcaa actttgatgt cgatgaggct agccaattca ttcaacaatt
    12901 tacaattaca aaacaaatcg aacaagtaga aaaactatta gaggagtagc atggaaactg
    12961 cattaattag tgtgattgtg ccagtctata atgtggcgca gtacctagaa aaatcgatag
    13021 cttccattca gaagcagacc tatcaaaatc tggaaattat tcttgttgat gatggtgcaa
    13081 cagatgaaag tggtcgcttg tgtgattcaa tcgctgaaca agatgacagg gtgtcagtgc
    13141 ttcataaaaa gaacgaagga ttgtcgcaag cacgaaatga tgggatgaag caggctcacg
    13201 gggattatct gatttttatt gactcagatg attatatcca tccagaaatg attcagagct
    13261 tatatgagca attagttcaa gaagatgcgg atgtttcgag ctgtggtgtc atgaatgtct
    13321 atgctaatga tgaaagccca cagtcagcca atcaggatga ctattttgtc tgtgattctc
    13381 aaacatttct aaaggaatac ctcataggtg aaaaaatacc tgggacgatt tgcaataagc
    13441 taatcaagag acagattgca actgacctat cctttcctaa ggggttgatt tacgaagatg
    13501 cctattacca ttttgattta atcaagttgg ccaagaagta tgtggttaat actaaaccct
    13561 attattacta ttttcataga ggggatagta ttacgaccaa accctatgca gagaaggatt
    13621 tagcctatat tgatatctac caaaagtttt ataatgaagt tgtgaaaaac tatcctgact
    13681 tgaaagaggt cgcttttttc agattggcct atgcccactt ctttattctg gataagatgt
    13741 tgctagatga tcagtataaa cagtttgaag cctattctca gattcatcgt tttttaaaag
    13801 gccatgcctt tgctatttct aggaatccaa ttttccgtaa ggggagaaga attagtgctt
    13861 tggccctatt cataaatatt tccttatatc gattcttatt actgaaaaat attgaaaaat
    13921 ctaaaaaatt acattagaac gggggtgacc aagtgattga tgggaaacga ttattattta
    13981 gtttgaccat agtcagttat gccttgacgc tagtaagtgg agttgtgtat ctgtttaata
    14041 ataataatgt tagcttactt tctactttat tgttcttgtt ggttagtagc ttaattgctt
    14101 gttggaatga tatcaagtat tacttaatcc attttatttt ctatttaacc atttttgtat
    14161 ttctggtatc aagaccgacc attgattatt ttagggatgg tgctttggat acctatcatc
    14221 caatagccta tcgttttgcc tttatagttg tcatggtttc gattctgggc ttgaccacag
    14281 gaggcattct ggctcgttac ttcatagcta ggaagaaaat aaaagtagca aatataggaa
    14341 attctctaaa agaggtttat atcaagcggt tacgctttgt atcactagga gtttttcttc
    14401 taacctatcc tttctatttc attcggttat ttgaacggct cttgtatcgt ttgcagactt
    14461 cctactatgc ctactatgca aattttgaaa gtaaactgcc ttattttacc tacattttgt
    14521 ctacctttac ggtctatgca atgtgtatgt atctagcaac caagccaaag aaattgcagg
    14581 ccacagcagt gcttgtctcc tttattgcag ctaatactat tcatttagca attgggacac
    14641 gaaatccctt tattttaagt attttatttg cttttgttta ttactttatg cgggagcaaa
    14701 ctgaaaaagg aaaatggatt gggtttaaag aaaagttagc gatttttgta ggttctccta
    14761 ttctcatgtt agcgatggga gtactcaatt atgtacggga taatgtccaa gtttcccata
    14821 caggtttctg ggatatctta cttgacttta tctataaaca agggactagt tttggtgttc
    14881 tggctcgagg ttttctattt aacagtagcc tcccttaccg agatttccgt aattttactt
    14941 ttggtcctgt tcttgattat tttgcaaggg ggagtttggg agccattttc ggaggaaaag
    15001 cctttgaaca tacaaccaat agtgtggaac tagctattga tagtaatagt tatgcccaca
    15061 atctatccta tcttgtcttg aacaaggaat acttgaaagg gcatggtatc ggaagtagtt
    15121 atatcatgga gttgtatacc gactatggta tgattggagt ctttctgctt agtttcttac
    15181 tcggcgtatt atttatagcc atgctgcaag tagcctatcg ctcaaggaca atcctatttg
    15241 ctttatccct actcatcttg aataatctat tctttatgcc aagaagcagc ttttcagaaa
    15301 gtttcttcaa tttatttaca atgcaattct ggggaattgt tcttgtgatt atatttgtag
    15361 caaaaatgct tacaaaggaa aactagtatc tactaaacaa aggagaaaaa aatcatgttt
    15421 gaacattatt cagtagctga tttgtttgca aatctttata aaaagcgaaa agcaaatatt
    15481 ttagctctca tcgctttatt tgctctcatt gctgtaccat ttacaattaa agcagttagg
    15541 aataaaaaca ctgtcaaaga tacaacaagt tattcaactt atcttatcta taaaatcact
    15601 cctccaaaag agtcggccaa aacgattttg aatcatcaaa ttggtggtta tagtgatttt
    15661 tatgggaaat tgattgatgg taatttgaat ggagcttatc ttttcaatga tgtagaaccc
    15721 agtgagttga aaaaaattgc cagtgaatta gacacgacag aaacaacctt gaaaaattca
    15781 acgaatgact attggtggaa aaaattgacc gtctactata tgattgacga tgcaggggtt
    15841 ggtgtgaaaa ttttgacatc aagtaaagat gccaatgact tgttagagaa aaaaattgat
    15901 gggttgattg agaaatttaa acatgcctat gcaaatgtga aaattgaaaa actggaaacc
    15961 atcaactcta aagaattgaa cgcaaatggt gaaacagcgc ttggcttaaa tgtgaaaaat
    16021 ctgattcttc gtttagttgt tattggagtg gtttgtgtga ttttggttgt gatgggaaat
    16081 gtgttagttt atctctttaa tccaacaatc aatagagtag gtgatttttc tcagtatcaa
    16141 attgattttg taacagagat tacaacaatt gctaacctag cagatgtttt gtcatacaaa
    16201 aatactggac aggaattgac catcgttagc tcaaataaag ctatcctaga taaattgaaa
    16261 cagagtcaag aagctttaaa aggaatgcat tttgtagatt tacaggatgt atcatctctt
    16321 ttggaaagag atacagtcct tcttgttgaa gagtacggag tgactcgtta taagaaattt
    16381 gagcaaagtc ttcaaattct cagaaactta aatcgttcta tccttggtgt agcaaccttt
    16441 aaattataag tattctgatg tataaggtct tcaaaatcgg ctaagagctg attttgaagg
    16501 ctttttctat ctgtctgcag aaattttctt ttggagtctc ctatagaaag accctaggga
    16561 aaatctatcc gtatagagga gccttctttt gataaaatcg taaaaatcta gtataataga
    16621 tagaactgaa agtatgaggt tactagcaat gaaaatgaaa caaattagtg atacaacttt
    16681 aaaaatcacg atgtctttag aggatttgat ggatcgtgga atggagattg ctgactttct
    16741 cgttcctcaa gaaaaaacag aagagttctt ttatgctatc ttggatgaac tagagatgcc
    16801 tgatagcttt ctggatacag gcatgttgag cttccgtgtg actccaaaac ctgataaggt
    16861 agatgtcttt gtgaccaagt caaagattga ccaaaatcta gattttgaag acttatcgga
    16921 tttgccagat atggaagaat tggctcaaat gtctccagat gaatttatca aaaccctgga
    16981 aaaaagcatc gcagacaaaa ccaaggatga tatcgaagcc attcaatctc ttgagcaagt
    17041 tgaagccaag gaagaagagc aagagcaggc tgaacaagaa gctgagagta agaaagaacc
    17101 ttacatctac tacatccttt cttttgctaa gttggctgac ttggtagttt ttgccaagac
    17161 agtgactttt gaaatggaaa cttctgaact ctacaaaatg aacgagcgct attatttgac
    17221 cattttagtg gatattgaaa atcatccaag cccatatcca gcttggctgt tggcccgtat
    17281 gcgcgagttt gcagacgata gtgatatcag tcgctcagtc ttacaagagt atggtcaagt
    17341 cttgatgagt cacgatgcag tgctcaatct gcaaaaaatc ggctaatcct ttctggaaag
    17401 ctattttcag attttaagaa gagcgaatcg tctgattcgt tttttctttt tatactgaaa
    17461 tagtgattta ctataatagg aattttcaca aaattctgtt ataatggcta tattagaaaa
    17521 tttcgaggag ataaagatga cagttaaaat tgctttacta ggatttggta ccgttgcaag
    17581 tggtgtgcct ttcctcctaa aggaaaatgg aggaaaaatc aatcaatcag cacattcaga
    17641 tatcaaagtt gctaaggtat tggtcaagga tgaagatgaa aaaaatcgct tgcttgcagc
    17701 agggaatgac tttaactttg taaccaatgt ggatgatatt ttatcagacc aggatattac
    17761 tatcgtagtg gaattgatgg ggcgtattga gcctgctaaa acctttatca ctcgtgcctt
    17821 ggaagctgga aaacacgttg ttactgctaa caaggacctt ttagctgtcc atggcgcaga
    17881 attgctagaa atcgctcaag ctaacaaggt agcactttac tacgaagcag cagttgctgg
    17941 tgggattcca attcttcgta ctttagcaaa ttccttggct tctgataaaa ttacgcgcgt
    18001 gcttggagta gtcaacggaa cttccaactt catggtgacc aagatggtgg aagaaggctg
    18061 gtcttacgat gatgctcttg cggaagcaca acgtctagga tttgcagaaa gcgatccgac
    18121 gaatgacgta gatgggattg atgcagccta caagatggtt attttgagtc aatttgcctt
    18181 tggcatgaag attgcctttg atgatgtagc ccacaaggga atccgcaata tcacaccaga
    18241 agacgtagct gtagctcaag agcttggtta cgtagtgaaa ttggttggtt ctattgagga
    18301 aacttcttca ggtattgctg cagaagtgac tccaaccttc ctacctaaag cgcacccact
    18361 tgctagtgtg aatggcgtaa tgaacgctgt ctttgtagaa tctattggta ttggtgagtc
    18421 tatgtactac ggaccaggtg cgggtcaaaa accaactgca acaagtgttg tagctgatat
    18481 tgtccgtatc gttcgtcgtt tgaatgatgg tactattggc aaagacttca acgaatatag
    18541 ccgtgacttg gtcttggcaa atcctgaaga tgtcaaagca aactactatt tctcaatctt
    18601 ggctctagac tcaaaaggtc aggtcttgaa gttggctgaa atcttcaatg ctcaagatat
    18661 ttcctttaag caaatccttc aagatggcaa agagggtgac aaggcgcgtg tcgttatcat
    18721 cacacacaag attaataaag cccagcttga aaatgtctca gctgaattga agaaggtttc
    18781 agaattcgac ctcttgaata ccttcaaggt gctaggagaa taagatgaag attattgtac
    18841 ctgcaaccag tgccaatatc gggccaggtt ttgactcggt cggtgtagct gtaaccaagt
    18901 atcttcaaat tgaggtctgc gaagaacgag atgagtggct gattgaacac cagattggca
    18961 aatggattcc acatgatgag cgtaatctct tgctcaaaat cgctttgcaa attgtaccag
    19021 acttgcaacc aagacgcttg aaaatgacca gtgatgtccc tttggcgcgc ggtttgggtt
    19081 cttccagctc ggttatcgtt gctgggattg aactagccaa ccaactgggt caactcaact
    19141 tatcagacca tgaaaaattg cagttagcga ccaagattga agggcatcct gacaatgtgg
    19201 ctccagccat ttatggtaat ctcgttattg caagttctgt tgaagggcaa gtctctgcta
    19261 tcgtagcaga ctttccagag tgtgattttc tagcttacat tccaaactat gaattacgta
    19321 ctcgcgacag ccgtagtgtc ttgcctaaaa aattgtctta taaggaagct gttgctgcaa
    19381 gttctatcgc caatgtagcg gttgctgcct tgttggcagg agacatggtg accgctgggc
    19441 aagcaatcga gggagacctc ttccatgagc gctatcgtca ggacttggta agagaatttg
    19501 cgatgattaa gcaagtgacc aaagaaaatg gggcctatgc aacctacctt tctggtgctg
    19561 ggccgacagt tatggttctg gcttctcatg acaagatgcc aacaattaag gcagaattgg
    19621 aaaagcaacc tttcaaagga aaactgcatg acttgagagt tgatacccaa ggtgtccgtg
    19681 tagaagcaaa ataaagaata gaagatagga tggggaaact cttgaccaga gggtttcata
    19741 tcctttttgt gaaaagaagt ttatactcaa tgaaaatcaa agagcaaact aggaagctag
    19801 ccgcaggctg ctcaaaacag tgttttgagg ttgtggatag aactgacgaa gtcagctcaa
    19861 gacactgttt tgaggttgca gatagaactg acgaagtcag ctcaagacac tgttttgagg
    19921 ttgcagatag aactgacgac gtcagtaaca tatatacggt aaggtgacgc taacgtggtt
    19981 tgaagagatt ttcgaagagt attagttaaa aacgtgataa aggagaaata aagatggcag
    20041 aaatttatct agcaggtggt tgtttttggg gcctagagga atatttttca cgcatttctg
    20101 gagtgctaga aaccagtgtt ggctacgcta atggtcaagt cgaaacgacc aattaccagt
    20161 tgatcaagga aacagaccat gcagaaacgg tccaagtgat ttacgatgag aaggaagtgt
    20221 cactcagaga gattttactt tattatttcc gagttatcga tcctctatct atcaatcaac
    20281 aagggaatga ccgtggccgc caatatcgaa ctgggattta ttatcaggat gaagcagatt
    20341 tgccagctat ctacacagtg gtgcaggagc aggaacgcat gctgggtcga aagattgcag
    20401 tagaagtgga gcaattacgc cactacattc tggctgaaga ctaccaccaa gactatctca
    20461 ggaagaatcc ttcaggttac tgtcatatcg atgtgaccga tgctgataag ccattgattg
    20521 atgcagcaaa ctatgaaaag cctagtcaag aggtgttgaa ggccagtcta tctgaagagt
    20581 cttatcgtgt cacacaagaa gctgctacag aggctccatt taccaatgcc tatgaccaaa
    20641 cctttgaaga ggggatttat gtagatatta cgacaggtga gccactcttt tttgccaagg
    20701 ataagtttgc ttcaggttgt ggttggccaa gttttagccg tccgatttcc aaagagttga
    20761 ttcattatta caaggatctg agccatggaa tggagcgaat tgaagttcgt tctcgttcag
    20821 gcagtgctca cttgggtcat gttttcacag atggaccgcg ggagttaggc ggcctccgtt
    20881 actgtatcaa ttctgcttct ttacgctttg tggccaagga tgagatggaa aaagcaggat
    20941 atggctatct attgccttac ttaaacaaat aaaacagaga gtggggcttc ccactttctt
    21001 catttctaga atatgaatag aagggattta tgaaacacct attatcttac ttcaaaccct
    21061 acatcaagga atcaatttta gcccccttgt tcaagctgtt agaagctgtt tttgagctct
    21121 tggttcccat ggtgattgct gggattgttg accaatcttt acctcaggga gatcaaggtc
    21181 atctctggat gcagattggc ctgctcctta tctttgcagt aattggcgtt ttagtggcct
    21241 tgatagctca attttactca gcaaaggcag cagtaggttt tgctaaggaa ttgacaaacg
    21301 atctttatcg tcatattctt tccttgccaa aggacagcag agaccgtctg acaacttcta
    21361 gtttggttac tcgcttgact tcggatacct accagattca gactggtatc aatcaattcc
    21421 tgcgtctctt tttacgagcg cccattatcg tttttggtgc catttttatg gcttatcgaa
    21481 tctcagctga gttgactttc tggttcttag tcttggttgc cattttgacc attgtcattg
    21541 tagggttatc tcgattggtc aatcctttct acagtagtct cagaaagaaa acggaccaac
    21601 tggttcagga aacgcgccag caattgcaag ggatgcgggt tattcgtgct tttggtcaag
    21661 aaaaacgaga gttacagatt tttcaaaccc ttaaccaagt ttatgctaga ttacaagaaa
    21721 agacaggttt ctggtctagt ttattaacac ctctgaccta tctgattgtc aatggaactc
    21781 ttctcgttat tatctggcaa ggctatattt caattcaagg aggagtgctc agtcaaggtg
    21841 ctctcattgc tcttatcaat tacctcttac agattttggt ggaattggtc aagctagcca
    21901 tgttgatcaa ttccctcaac cagtcctata tctcagtcaa gcgaatcgag gaagtctttg
    21961 ttgaggctcc agaggatatc cattcagagt tagaacaaaa gcaagctacc agagataagg
    22021 ttttacaagt ccaagaattg acttttacct atcctgatgc ggcccagcct tctctgagat
    22081 acatttcctt tgatatgact caaggacaaa ttctaggtat catcggggga actggttctg
    22141 gtaaatcaag cttggtgcaa ctcttacttg gactttatcc agtagacaag gggaacattg
    22201 acctttatca aaatggacgt agtcctctta atttggagca gtggcggtct tggattgcct
    22261 atgtacctca aaaggtcgaa ctctttaaag gaaccattcg ttccaacttg actctaggtt
    22321 tcaatcaaga agtatctgac caggaactct ggcaggcctt ggagattgcg caagctaagg
    22381 attttgtcag tgaaaaggaa ggactcttgg atgctctagt tgaggcaggg gggcgaaatt
    22441 tctcaggtgg acaaaaacaa agattgtcta tcgcccgagc agtcttgcgc caagctccgt
    22501 ttctcatcct agatgatgca acctcggcac tggataccat tacagagtcc aagctcttga
    22561 aagctattag agaaaatttt ccaaacacga gcttaatttt gatctctcaa cgaacctcaa
    22621 ctttacagat ggcggaccag attctcctct tggaaaaagg tgagttgcta gctgttggca
    22681 agcacgatga cttgatgaaa tccagccaag tctattgtga aatcaatgca tcccaacatg
    22741 gaaaggagga ctagaatgaa acgacaaact gtaaaccaga cgctcaaacg tttagccgta
    22801 gatttagcaa gccatccttt cctccttttc ctagcctttc taggaactat tgctcaagtt
    22861 ggcttatcaa tttacctacc tattctgatt gggcaggtca ttgaccaagt cctagtggct
    22921 ggttcatcac cagttttttg gcagattttt ctccagatgc tcttggtggt aataggaaat
    22981 actctggtac aatgggccaa tcctctcctc tataatcgtc taatcttctc ttataccaga
    23041 gatttacggg agcgaatcat ccataagctc catcgtttac cgattgcctt tgtagatagg
    23101 caaggtagtg gagagatggt tagtcgtgta accacggaca tcgaacagtt ggcaactggc
    23161 ttgaccatga tttttaacca atttttcatt ggtgttttga tgattttggt cagtattcta
    23221 gccatgctcc aaattcatct cctcatgact ctcttagtct tgctgttgac gccactgtcc
    23281 atggtgattt cacgctttat tgccaagaaa tcctatcatc tcttccagaa gcaaacagag
    23341 acgaggggaa ttcagactca gttgattgaa gaatcgctta gtcagcagac tataatccag
    23401 tccttcaatg ctcaaacaga atttatccaa agattgcgtg aggctcatga caactactca
    23461 ggctattctc agtcagccat cttttattct tcaacggtca atccttcgac tcgctttgta
    23521 aatgcactca tttatgccct tttagctgga gtaggagctt atcgtatcat gatgggttca
    23581 gccttgaccg tcggtcgttt agtgactttt ttgaactatg ttcagcaata caccaagccc
    23641 tttaacgata tttcttcagt gctagctgag ttgcaaagtg ctctggcttg cgtagagcgt
    23701 atctatggag tcttagatag ccctgaagtg gctgaaacag gtaaggaagt cttgacgacc
    23761 agtgaccaag ttaagggagc tatttccttt aaacatgtct cttttggcta ccatcctgaa
    23821 aaaattttga ttaaggactt gtctatcgat attccagctg gtagtaaggt agccatcgtt
    23881 ggtccgacag gtgctggaaa atcaactctt atcaatctcc ttatgcgttt ttatcccatt
    23941 agctcgggag atatcttgct ggatgggcaa tccatttatg attatacacg agtatcattg
    24001 agacagcagt ttggtatggt gcttcaagaa acctggctca cacaagggac cattcatgat
    24061 aatattgcct ttggcaatcc tgaagccagt cgagagcaag taattgctgc tgccaaagca
    24121 gctaatgcag actttttcat ccaacagttg ccacagggat acgataccaa gttggaaaat
    24181 gctggagaat ctctctctgt cggccaagct cagctcttga ccatagcccg agtctttctg
    24241 gctattccaa agattcttat cttagacgag gcaacttctt ccattgatac acggacagaa
    24301 gtgctggtac aggatgcctt tgcaaaactc atgaagggcc gcacaagttt catcattgct
    24361 caccgtttgt caaccattca ggatgcggat ttaattcttg tcttagtaga tggtgatatt
    24421 gttgaatatg gtaaccatca agaactcatg gatagaaagg gtaagtatta ccaaatgcaa
    24481 aaagctgcgg cttttagttc tgaataagcc attctctttt gaaagtttat ggacgaaaaa
    24541 agttgccttc gagtgacttt tttgttacaa tagctagaaa aattgttcac tgtaatactc
    24601 aatgaaaatc aaagagcaaa ctaggaagct agccgtaggt tgctcaaagc acagctttga
    24661 ggttgtagat aagactgacg aagtcagttc aaaacactgt tttgaggttg cagatagaac
    24721 tgacgaagtc agctcaaaac actgttttga ggttgcagat agaactgacg aagtcagctc
    24781 aaaacactgt tttgaggttg cagatagaac tgacgaagtc agtaaccaca cctacggcaa
    24841 agtgaatctg aagtggtttg aagagagtac aacttgtctt ttagaaaagg agcctataat
    24901 gaaagtcttt cagcatgtaa atatcgtgac ttgtgatcaa gatttccatg tttatcttga
    24961 tggaatctta gcagtcaagg attctcaaat cgtctatgtc ggtcaagata agccagcgtt
    25021 tttagagcaa gctgagcaga ttatagacta tcagggagct tggattatgc ctggtttggt
    25081 caattgtcac atccattctg caatgacagg tctgagaggg atccgagatg acagcaatct
    25141 ccatgaatgg ctcaatgact atatttggcc agcagaatct gagtttactc ccgacatgac
    25201 taccaatgcg gtcaaagaag ccctgacaga gatgctccag tcaggaacaa caacctttaa
    25261 cgatatgtat aatcccaatg gtgtggatat ccagcaaatt tatcaggtgg tgaaaacttc
    25321 caagatgcgt tgttattttt ctccgactct cttttcttca gagacagaaa caactgctga
    25381 gactataagt agaactcgat ccatcataga cgaaatctta aaatataaaa atccaaattt
    25441 caaggttatg gtagcacctc attctccgta tagctgcagt agagacttgc tggaagcgag
    25501 tttggaaatg gcaaaagagc taaatattcc gctccatgtc catgtggcgg agaccaagga
    25561 ggagtcagga attatcctca aacgatacgg caaacgcccc cttgcttttc ttgaagaact
    25621 gggttattta gatcatccgt ccgtatttgc tcacggggtc gaattaaacg agagagaaat
    25681 tgaacgcttg gcatcttctc aagtggctat cgcccacaat cctatcagta acctcaaact
    25741 ggcatcagga attgctccaa ttatccagct ccaaaaagcg ggagtagcag tcggaattgc
    25801 gactgactcg gttgcttcca ataacaatct agatatgttt gaggaaggaa ggactgcagc
    25861 tcttcttcag aagatgaaaa gtggggatgc cagccagttt ccaatcgaaa cagctctcaa
    25921 ggtactgaca atcgaagggg ctaaggtcct tggaatggaa aatcagatag gaagtctgga
    25981 agtcggcaag caagcagatt ttctggtcat tcaaccacaa gggaaaattc atctccaacc
    26041 tcaggaaaat atgctgtctc acctggttta tgcagttaaa tctagtgatg tagatgatgt
    26101 ttatatcgcc ggagaacagg ttgttaagca aggtcaagtc ctgacagtag aactttaaaa
    26161 gaaaaattac gaaaaatttt aaaaaaagtt tgcaaaaatc ttgcattctt tttttgacta
    26221 tgctatactt atatacggtt taaaaaaact gcctaagaca gtaggggagc tcgactcata
    26281 aatatcctac cgaggacaaa acgtatcatg taaaaagaag cgtattgtac tttcgtgtct
    26341 aggtttgggc gcgtttttct ttttgaaaaa ttccccaagc aaaataatta cggaggtgaa
    26401 cacactaatg agtgaagcaa ttattgctaa aaaagcggaa ctagttgacg tagtagctga
    26461 aaaaatgaaa gctgctgcat ctatcgtcgt tgtagacgct cgtggtttga cagttgagca
    26521 agatacagtt cttcgtcgtg agcttcgtgg aagcgaagtt gagtataaag ttattaaaaa
    26581 ctcaatcttg cgtcgtgcag ctgaaaaagc tggtcttgaa gatcttgcat ctgtatttgt
    26641 tggaccatct gcagtagcat tttctaatga agatgttatc gcaccagcga aaatcttgaa
    26701 cgacttttct aaaaacgctg aagcacttga aattaaaggt ggtgcaatcg aaggcgctgt
    26761 cgcatctaaa gaagagattc ttgcacttgc aactcttcca aaccgcgaag gacttctttc
    26821 tatgctcctt tctgtacttc aagcgccagt gcgcaacgtt gctcttgcag tcaaagcggt
    26881 tgcagaaagc aaagaagacg cggcttaatc ttaagctata cagcgtagcc tagctacgaa
    26941 aaaaactatt ataaaattta aaacttattt ggaggaaata acaatggcat tgaacattga
    27001 aaacattatt gctgaaatta aagaagcttc aatccttgaa ttgaacgacc ttgtaaaagc
    27061 tatcgaagaa gaatttggtg taactgcagc tgctcctgta gctgttgctg cagctgatgc
    27121 agctgatgct ggtgctgcta aagattcatt cgacgttgaa ttgacatctg caggcgacaa
    27181 aaaagttggc gttatcaaag ttgtacgtga aatcactggt cttggtctta aagaagctaa
    27241 agaacttgtt gacggtgcac cagcacttgt taaagaaggc gttgcaactg cagaagctga
    27301 agaaatcaaa gctaaattgg aagaagctgg agcttcagtt actcttaaat aatagagtat
    27361 cgcaatttga ttgcggaatc cctatttacc agtctttgag agcgataagc gattgataga
    27421 aactgataaa ttgatttggt ttcctgccaa aaattctttg gcaggatttt tgttttaata
    27481 aactttcggg ggtagacact agattgtcta cccctttttt tgtgtttcgg aggtaattat
    27541 gcaaaaggaa ggacagtcat cacgtcaatt cgtgaagagt catctcatga ctatcatggg
    27601 agttgatatt gtaaaagcaa ctcagttagt tgatgaaatg gaacaagtag gtttaatccg
    27661 atttgatgaa tttggaaatg ttggaatttt agtcttggag ggacaataat gaagcgtatt
    27721 accgctaatc aatatcagac atcagagcgt tattataagc tccccaaact tttatttgag
    27781 agtgaacggt ataagaatat gaaactggag gttaaggtgg tttactcagt tttaaaagat
    27841 cggttggagt tgtctttgag caaaggttgg attgatgagg atggggctat ttatttgatt
    27901 tattccaatt caaatttgat ggcactttta ggctgttcaa agtcaaaatt actctccatg
    27961 tgagtttgaa gtgacatttt tagatgatta ccataaaaaa cacaactacc cactatttta
    28021 cgaatcctat cttcaaaacg ttatggaatt ccttgaaagt caagacataa agaatggggt
    28081 tgatgccttt gtagatgatc atcaaaatct cgtttttgtt ttatatggac aaggctatcg
    28141 agcagaggga aaagagggaa tacttacaac tcaagtaact gtaaaagctt atgatgaaga
    28201 caagaaaccg attaacttcg caaatttatt agattcctta atcgtctcag aatatcaaat
    28261 ggaaccgaat ctttggaagg tctcccatga ttgatctcta tctaagtaaa aatagccaaa
    28321 gaaatcaact tcttttggat ttctttcaaa agtatggcat agaggtcact cctcattcta
    28381 tttctgaaat gacaaaggac aaattaattg aaatgatgag ctattcttca gattgttttg
    28441 agtttctatc tcccaattta ttacgattta agaaccgtga caatctaaga ttaacggatt
    28501 tcattgaaat gatattaaaa aatcctgaac tatgcatcag gcttcctctt gcggtttcaa
    28561 ataagagagt ttatccaaat ctgaatttgg aagaggctag agctctattg ccaagagata
    28621 cgaaacaatt gatttacatg gcacaaacac attatttatc tagttaaagg agaagcaata
    28681 tggctgaacg attttgggag aacttgtcca ttattttggc tgaaagaaat attagctgga
    28741 ttgagttaac cagaaaaatg tttgcgggag agtttcacta tccaagtgaa ttgaatcgtt
    28801 tgtatcaaaa gatacgccac tacaagatgg aacaacgaat gcctcaaagt ccatgggtag
    28861 aaaggattgt gcaggtatta gatttagatt atgaagattt atttcggagg taactatgaa
    28921 aagaataatt ccagtttata tattccaaca agtaaatgtc ttattggtat ccctatactt
    28981 actgaaattg ctttgtattg gtgagttaac catactacag attctctatt gtgcgtcgct
    29041 catttctttt ttatggatgt atggtcaacg aaaacaagtg gtcaaggtca atatgaaaac
    29101 taggatgaaa tggcttggta ttggattcgt tagcctactg attataagcc tatgttttag
    29161 tctgattcat gctcaaggaa ccacgaatca agcaaactta attggccttc aacatcaggt
    29221 tccttggttt tcatttttat tgttcttaat caatgcgagt atggttgaag aatttctgta
    29281 tcgagaaatt ttatggaact tggtcagaaa attagatatt cgagttgctt tgacaagtgt
    29341 tttatttgcc ttagtacatc atccaggaac cattctagct tggtgtttat atgtttcact
    29401 tgggatcttt ttagggatgg tgcgctataa atcggactta tggggaagta tgggtctaca
    29461 tttggtgtgg agcctactag tttatagttt gctgcttttt taaaataggt aacctgattt
    29521 ttaggtaact tctaaaacta acttccagtt ttgggagaga gatggaagtt actttgaaaa
    29581 gttacggaaa cattattttc tacgtgacaa cattgtatca ttgcttgcat tttactgctg
    29641 gagagagtat aatgaaggtg gataaagcac ttaatcccaa aaatttaaat aggaggagtt
    29701 agctatggca gaagaagtat taaatcttca attagtatct gttcaagttg acgaaacaga
    29761 tgaagttgat ggaatgcgat ttagtacatt cagtacaaac cgttgcggta actggagtgc
    29821 ttttagttgg gaaaattgtt aattcattta aattgtaaac tttagagatt ctctggagtt
    29881 atggatgtcg ttccaatatg tgcacgttgg aatgttagtg cttatatggg ggaacagaat
    29941 cctctcttga ttgaagacaa gctagtcatt aggctggttt gtctttttgt caactgtagt
    30001 gggttgatat aatagtatta gtgagtggga taaaagtttc atttagttta ttcagtacaa
    30061 atttaacggg tcaagattta actaaaggag aagtaatatg gctgaacgat tttgggagaa
    30121 cttgtccatt attttggctg aaagaaatat cagctggatt gagttaacca gaaaaatgtt
    30181 tgcgggagag tttcactatc caagtgaatt gaatcgttta tatcaaaaga ttcgccacta
    30241 caagatggaa caacgaatgc ctcaaagtcc atgggtagaa aggattgtgc agatattaga
    30301 tttagattat gaagatttat ttcggaggta actatgaaaa gaataattcc agtttatata
    30361 ttccaacaag taaatgtcct attggtatct ctatacttat tgaaatttct ttgtatcggt
    30421 gagttaacta tactacaggt tctctatggt gcgtctcttt tttctttttt atggatgtat
    30481 ggtcaacgaa aacaagtggt caaggtcaat atgaaaacta ggatgaaatg ccttggtatt
    30541 ggactagcta gtctactgat tataagtcta tgttttagcc tgattcatgc tcaaggaagc
    30601 acgaatcaaa caaatttaat tggccttcaa catcaagttc cttggttttc atttttattg
    30661 ttcttaatca atgcgagtat ggttgaagaa tttctgtatc gtgaaatttt atggaacttg
    30721 gttagaaaat tagatattcg agttgctttg acaagtgttt tatttgcctt agtacatcat
    30781 ccaggaacca ttctagcttg gtgtctgtac gtttcacttg gaatgttttt aggtatggtg
    30841 cgctataaat ctgacttatg gggaagtatg gggttacatt tggtgtggaa ctttttagtt
    30901 tatagtttgc tgctttttta aaataggtga cctgatttat ctcataaatc tgtagttt
//
LOCUS       DAVLXH010000021        28985 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00028199
            SAMN33607166-rid17955573.denovo.021, whole genome shotgun sequence.
ACCESSION   DAVLXH010000021 DAVLXH010000000
VERSION     DAVLXH010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607166
            Sequence Read Archive: SRR23725544
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 28985)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28985)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721421.1
            Genome Coverage       :: 115x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:42:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,210
            CDSs (total)                      :: 2,161
            Genes (coding)                    :: 2,023
            CDSs (with protein)               :: 2,023
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 73 of 138
            Pseudo Genes (incomplete)         :: 60 of 138
            Pseudo Genes (internal stop)      :: 40 of 138
            Pseudo Genes (multiple problems)  :: 31 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28985
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607166-rid17955573.denovo.021"
                     /strain="AUSMDU00028199"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1349"
     gene            <1..327
                     /locus_tag="VYO11_001068"
     CDS             <1..327
                     /locus_tag="VYO11_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001081168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1595653.1"
                     /translation="IIYFYSQVKVVDKLTDSESKKYGEYIDLYESCRQNNLSVLLNFL
                     QNSDDKRGVIASNSVRIMFESLDKADQIAALNICRNYVARENVLNKEDAEKLLNEIDK
                     KLEISR"
     gene            383..1078
                     /locus_tag="VYO11_001069"
     CDS             383..1078
                     /locus_tag="VYO11_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001144916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1595654.1"
                     /translation="MPVNEYGQMIGESMEGYTPGALPSIDFLEGRYARIEALSVEKHA
                     EDLLAVYGPDTPREMWTYLFQEPVADMGELVSLLNQMLARKDRFYYAIIDKATGKALG
                     TFSLMRIDQNNRVIEVGAVTFSPELRGTRIGTEAQYLLARYIFEELNYRRYEWKCDAL
                     NLPSRRVAERLGFVYEGTFRQAVVYKGRTRDTDWLSMIDMDWPQVKDRLETWLRPENF
                     DKNGQQYKSLREL"
     gene            1090..1506
                     /locus_tag="VYO11_001070"
     CDS             1090..1506
                     /locus_tag="VYO11_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1595655.1"
                     /translation="MITIKKQEIVKLEDVLHLYQAVGWTNYTHQPEMLEHALSHSLVI
                     YLALDGDAVVGLIRLVGDGFSSVFVQDLIVLPIYQRQGIGSALMKEALKDYKDAYQVQ
                     LVTEETEKNVGFYRSMGFEILSTYNCIGMTWANREK"
     gene            complement(2133..2225)
                     /locus_tag="VYO11_001071"
     CDS             complement(2133..2225)
                     /locus_tag="VYO11_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HEV1595656.1"
                     /translation="MMELVLKTIIGPIVVGVVLRIVDKWLNKDK"
     gene            2386..3357
                     /gene="ruvB"
                     /locus_tag="VYO11_001072"
     CDS             2386..3357
                     /gene="ruvB"
                     /locus_tag="VYO11_001072"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000502070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HEV1595657.1"
                     /translation="MGDEELVERTLRPQYLREYIGQDKVKDQLQIFIEAAKMRDEALD
                     HVLLFGPPGLGKTTMAFVIANELGVNLKQTSGPVIEKAGDLVAILNELEPGDVLFIDE
                     IHRLPMSVEEVLYSAMEDFYIDIMIGAGEGSRSVHLELPPFTLIGATTRAGMLSNPLR
                     ARFGITGHMEYYAHADLTEIVERTADIFEMEITHEAASELALRSRGTPRIANRLLKRV
                     RDFAQIMGNGVIDDIITDKALTMLDVDHEGLDYVDQKILRTMIEMYSGGPVGLGTLSV
                     NIAEERETVEDMYEPYLIQKGFIMRTRSGRVATAKAYEHLGYEYSEK"
     gene            3338..3910
                     /locus_tag="VYO11_001073"
     CDS             3338..3910
                     /locus_tag="VYO11_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001098890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase family protein"
                     /protein_id="HEV1595658.1"
                     /translation="MNTVKNKQEILEAFRENPDMMAILTIIRDLGLKDSWLAAGSVRN
                     FIWNLLSDKSPFDHETDIDVIFFDPDFSYEETLLLEKKLREDFPQYQWELKNQVYMHQ
                     HSPHTASYTSSRDAMSKYPERCTTVGLRLNEESDFELYAPYGLEDILNFQVRPTPHFL
                     ENEDRMELYQTRLSKKNWQEKWKNLIFKNT"
     gene            4141..4899
                     /locus_tag="VYO11_001074"
     CDS             4141..4899
                     /locus_tag="VYO11_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HEV1595659.1"
                     /translation="MFGFFKKDKAVEVEVPTQVPAHIGIIMDGNGRWAKKRMQPRVFG
                     HKAGMEALQTVTKAANKLGVKVITVYAFSTENWTRPDQEVKFIMNLPVEFYDNYVPEL
                     HANNVKIQMIGETDRLPKQTFEALTKAEELTKNNTGLILNFALNYGGRAEITQALKLI
                     SQDVLDAKINPGDITEELIGNYLFTQHLPKDLRDPDLIIRTSGELRLSNFLPWQGAYS
                     ELYFTDTLWPDFDEAALQEAILAYNRRHRRFGGV"
     gene            4908..5711
                     /locus_tag="VYO11_001075"
     CDS             4908..5711
                     /locus_tag="VYO11_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HEV1595660.1"
                     /translation="MTQDLQKRTLFAGIALAIFLPILMIGGLLLQIAIGIIAMLAMHE
                     LLKMRGLETMTMEGLLTLFATFALTIPLENYLTFLPVDGNVVAYSVLISIMLGTTVFS
                     KSYTIEDAVFPLAMSFYVGFGFNALLDARVAGLDKALLALCIVWATDSGAYLVGMNYG
                     KRKLAPRVSPNKTLEGALGGILGAILVTIIFMIVDSTVALPYGIYKMSVFAIFFSIAG
                     QFGDLLESSIKRHFGVKDSGKFIPGHGGVLDRFDSMLLVFPIMHLFGLF"
     gene            5733..6992
                     /gene="rseP"
                     /locus_tag="VYO11_001076"
     CDS             5733..6992
                     /gene="rseP"
                     /locus_tag="VYO11_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HEV1595661.1"
                     /translation="MLGILTFILVFGIIVVVHEFGHFYFAKKSGILVREFAIGMGPKI
                     FAHIGKDGTAYTIRILPLGGYVRMAGWGDDTTEIKTGTPVSLTLADDGKVKRINLSGK
                     KLDQTALPMQVTQFDFEDKLFIKGLVLEEEKTFAVDHDATVVEADGTEVRIAPLDVQY
                     QNATIWGKLITNFAGPMNNFILGVVVFWVLIFMQGGVRDVDTNQFHIMPQGALAKVGV
                     PETSQITKIGSHEVSNWESLIQAVETETKDKTAPTLDVTISEKGSDKQVTVTPEDSQG
                     RYLLGVQPGVKSDFLSMFVGGFTTAADSALRILSALKNLIFQPDLNKLGGPVAIFKAS
                     SDAARNGIENVLYFLAMISINIGIFNLIPIPALDGGKIVLNILEAIRRKPLKQEIETY
                     VTLAGVVIMVVLMIAVTWNDIMRLFFR"
     gene            7005..8858
                     /locus_tag="VYO11_001077"
     CDS             7005..8858
                     /locus_tag="VYO11_001077"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HEV1595662.1"
                     /translation="MKQSKMPIPTLREMPSDAQVISHALMLRAGYVRQVSAGVYSYLP
                     LANRVIEKAKNIMRQEFEKIGAVEMLAPALLSAELWRESGRYETYGEDLYKLKNREKS
                     DFILGPTHEETFTAIVRDSVKSYKQLPLNLYQIQPKYRDEKRPRNGLLRTREFIMKDA
                     YSFHANYDSLDSVYDEYKAAYERIFTRSGLDFKAIIGDGGAMGGKDSQEFMAITSART
                     DLDRWVVLDKSVVSFDEIPAEVQEEIKAELLKWIVSGEDTIAYSSESSYAANLEMATN
                     EYKPSNRVVAEEEVTRVATPDVKSIDEVAAFLNVPEEQTIKTLFYIADGELVAALLVG
                     NDQLNEVKLKNHLGADFFDVASEEEVANVVQAGFGSLGPVGLPENIKIIADRKVQDVR
                     NAVVGANEDGYHLTGVNPGRDFTAEYVDIREVREGEISPDGQGVLNFARGIEIGHIFK
                     LGTRYSASMGADVLDENGRAVPIIMGCYGIGVSRLLSAVMEQHARLFVNKTPKGEYRY
                     AWGINFPKELAPFDVHLITVNVKDEEAQALTEKLEASLMGAGYEVLTDDRNERVGVKF
                     SDSDLIGLPIRITVGKKAADGIVEVKIKATGDTIEVHADNVLETLEILSKK"
     gene            8957..10336
                     /gene="bglA"
                     /locus_tag="VYO11_001078"
     CDS             8957..10336
                     /gene="bglA"
                     /locus_tag="VYO11_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000943526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HEV1595663.1"
                     /translation="MLRFPKDFVWGSSTSGPQTEGRVAGDGKGDNLWDYWFQVEPNRY
                     YNGIGSDKTSTFYENWERDIELLLETGHTAFRTSIQWSRIFPQGCGKVNTQGVDFYRK
                     VFEAIKAKGIRLLVNLYHFDLPFALQEDGDGWENKATVSAYEDYARFCFETYGDLVDQ
                     WITFNEPIVPVEFGYFYDAHYPHKVDAEAAVKVAYHTQLASSRAVKACHELLPDSKIG
                     IVLNLTPAYPRSQHPADVKAARIAALFQAQSFLDPSVLGTYPQELVEILHEHGLLPDA
                     TEEELELIRDNTVDFLGVNYYQPLRVMAPRFAKHPESPLLPEHFYEPYVMPGRKINSH
                     RGWEIYEQGIYDIAQNIKENYGNIEWMLTENGMGVEGEEKFRQDGMIQDDYRIDFVKG
                     HLRELHRAIEDGANCKGYLIWTFIDCWSWLNSYKNRYGLVELDLETQERRLKKSGHWF
                     KKLSDNNGF"
     gene            10528..12336
                     /gene="glmS"
                     /locus_tag="VYO11_001079"
     CDS             10528..12336
                     /gene="glmS"
                     /locus_tag="VYO11_001079"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014621492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HEV1595664.1"
                     /translation="MCGIVGVVGNTNATDILIQGLEKLEYRGYDSAGIFVLDGADNHL
                     VKAVGRIAELSAKTAGVEGTTGIGHTRWATHGKPTEDNAHPHRSETERFVLVHNGVIE
                     NYLEIKEEYLAGHHFKGQTDTEIAVHLIGKFAEEEGLSVLEAFKKALHIIRGSYAFAL
                     VDSQDPEVIYVAKNKSPLLIGLGEGYNMVCSDAMAMIRETNQYMEIHDQELVIVKADS
                     VEVQDYDGNRRERASYTAELDLSDIGKGTYPYYMLKEIDEQPTVMRKLIQAYTDDAGQ
                     VVVDPAIIKAVQDADRIYILAAGTSYHAGFASKKMLEELTDTPVELGISSEWGYGMPL
                     LSKKPLFIFISQSGETADSRQVLVKANEMGIPSLTVTNVPGSTLSREANYTMLLHAGP
                     EIAVASTKAYTAQIAALAFLAKAVGEANGNAKAQAFDLIHELSIVAQSIESTLSEKET
                     IEAKVRELLETTRNAFYIGRGQDYYVAMEASLKLKEISYIQCEGFAAGELKHGTIALI
                     EEGTPVLALLSDPVLANHTRGNIQEVAARGAKVLTIAEENVAKDTDDIVLTTVHPYLS
                     PISMVVPTQLVAYFATLHRGLDVDKPRNLAKSVTVE"
     gene            12455..13504
                     /locus_tag="VYO11_001080"
     CDS             12455..13504
                     /locus_tag="VYO11_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="HEV1595665.1"
                     /translation="MVELGISTFGEITELEGTGQTYSHAERIRQLVAEIELADKVGLD
                     VYGIGEHHRADFAVSAPEIVLAAGAVNTKKIRLTSAVSILSSMDPIRLFQQYATIDAL
                     SNGRAEIMAGRGSFTESFPLFGYDLKDYDSLFDEKLDLLQLVNEKTKLDWQGRLTQTI
                     AGKEVYPRPVQDKLPLWIATGGHVESTVKIAQAGLPIVYAIIDGNPRYFKKLIQAYRE
                     IGSEAGHADKDLKVGAHSWGWIAEDGEQAVKDYFHPTKQVVDAISKDRPHWQELRYEQ
                     YLDQVGSNGAMFVGNPDQVAEKLIRMIEDLGLDRFMLHLPLGSMPHDQVLRAIELFGT
                     QVAPKVRAYFAMKEA"
     gene            complement(13604..17401)
                     /gene="spuA"
                     /locus_tag="VYO11_001081"
     CDS             complement(13604..17401)
                     /gene="spuA"
                     /locus_tag="VYO11_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored pullulanase SpuA"
                     /protein_id="HEV1595666.1"
                     /translation="MRKTPSHTEKKMVYSIRSLKNGTGSVLIGASLVLLAMATPTISS
                     DESTPTTNEPNNRNTTTLAQPLTDTAAGSGKNESDISSPRNANASLEKTEEKPATEPT
                     TSTSPVTTETKAEEPIEDNYFRIHVKKLPEENKDAQGLWTWDDVEKPSENWPNGALSF
                     KDAKKDDYGYYLDVKLKGEQAKKISFLINNTAGKNLTGDKSVEKLVPKMNEAWLDQDY
                     KVFSYEPQPAGTVRVNYYRTDGNYDKKSLWYWGDVKNPSSAQWPDGTDFTATGKYGRY
                     IDIPLNEAAREFGFLLLDESKQGDDVKIRKENYKFTDLKNHSQIFLKDDDESIYTNPY
                     YVHDIRMTGAQHVGTSSIESSFSTLVGAKKEDILKHSNITNHLGNKVTITDVAIDEAG
                     KKVTYSGDFSDTKHPYTVSYNSDQFTTKTSWRLKDETYSYDGKLGADLKEEGKQVDLT
                     LWSPSADKVSVVVYDKNDPDKVVGTVALEKGERGTWKQTLDSTNKLGITDFTGYYYQY
                     QIERQGKTVLALDPYAKSLAAWNSDDAKIDDAHKVAKAAFVDPAKLGPQDLTYGKIHN
                     FKTREDAVIYEAHVRDFTSDPAIAKDLTKPFGTFEAFIEKLDYLKDLGVTHIQLLPVL
                     SYYFVNELKNHERLSDYASSNSNYNWGYDPQNYFSLTGMYSSDPKNPEKRIAEFKNLI
                     NEIHKRGMGAILDVVYNHTAKVDIFEDLEPNYYHFMDADGTPRTSFGGGRLGTTHHMT
                     KRLLVDSIKYLVDTYKVDGFRFDMMGDHDAASIEEAYKAARALNPNLIMLGEGWRTYA
                     GDENMPTKAADQDWMKHTDTVAVFSDDIRNNLKSGYPNEGQPAFITGGKRDVNTIFKN
                     LIAQPTNFEADSPGDVIQYIAAHDNLTLFDIIAQSIKKDPSKAENYAEIHRRLRLGNL
                     MVLTAQGTPFIHSGQEYGRTKQFRDPAYKTPVAEDKVPNKSHLLRDKDGNPFDYPYFI
                     HDSYDSSDAVNKFDWTKATDGKAYPENVKSRDYMKGLIALRQSTDAFRLKSLQDIKDR
                     VHLITVPGQNGVEKEDVVIGYQITAPNGDIYAVFVNADEKAREFNLGTAFAHLRNAEV
                     LADENQAGSVEIANPKGLEWTEKGLKLNALTATVLRVSQNGTSHESTAEEKPDSIPSK
                     PEHQNEASHPAYQDPAPEARPDSTKPDAKVADAENKPSQATADSQAEQPAQEAQASSV
                     KEAVQNESVENSSKKNIPATPDRQAELPNTGIKNENKLLFAGISLLALLGLGFLLKNK
                     KEN"
     gene            17818..18231
                     /gene="rpsL"
                     /locus_tag="VYO11_001082"
     CDS             17818..18231
                     /gene="rpsL"
                     /locus_tag="VYO11_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HEV1595667.1"
                     /translation="MPTINQLVRKPRKSKVEKSKSPALNVGYNSHKKVQTNVSSPQKR
                     GVATRVGTMTPKKPNSALRKFARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQGRSKYGTKRPKA"
     gene            18251..18721
                     /gene="rpsG"
                     /locus_tag="VYO11_001083"
     CDS             18251..18721
                     /gene="rpsG"
                     /locus_tag="VYO11_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HEV1595668.1"
                     /translation="MSRKNRAPKRDVLPDPLYNSQLVTRLINRVMLDGKRGTAASIVY
                     GAFEQIKEATGNDALEVFETAMENIMPVLEVRARRVGGSNYQVPVEVRPERRTTLGLR
                     WLVTIARLRGEHTMQDRLAKEILDAANNTGAAVKKREDTHRMAEANRAFAHFRW"
     gene            19146..21227
                     /gene="fusA"
                     /locus_tag="VYO11_001084"
     CDS             19146..21227
                     /gene="fusA"
                     /locus_tag="VYO11_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HEV1595669.1"
                     /translation="MAREFSLEKTRNIGIMAHVDAGKTTTTERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWNNHRVNIIDTPGHVDFTIEVQRSLRVLDGA
                     VTVLDSQSGVEPQTETVWRQATEYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGSEDDFRGIIDLIKMKAEIYTNDLGTDILEEDIPAEYLDQAQEYREKLIEAV
                     AETDEELMMKYLEGEEITNEELKAGIRKATINVEFFPVLCGSAFKNKGVQLMLDAVID
                     YLPSPLDIPAIKGINPDTDAEETRPASDEEPFAALAFKIMTDPFVGRLTFFRVYSGVL
                     QSGSYVLNTSKGKRERIGRILQMHANSRQEIDTVYSGDIAAAVGLKDTTTGDSLTDEK
                     SKIILESINVPEPVIQLMVEPKSKADQDKMGIALQKLAEEDPTFRVETNVETGETVIS
                     GMGELHLDVLVDRMRREFKVEANVGAPQVSYRETFRASTQARGFFKRQSGGKGQFGDV
                     WIEFTPNEEGKGFEFENAIVGGVVPREFIPAVEKGLVESMANGVLAGYPMVDVKAKLY
                     DGSYHDVDSSETAFKIAASLSLKEAAKSAQPAILEPMMLVTITVPEENLGDVMGHVTA
                     RRGRVDGMEAHGNSQIVRAYVPLAEMFGYATVLRSASQGRGTFMMVFDHYEDVPKSVQ
                     EEIIKKNKGED"
     gene            21331..25722
                     /locus_tag="VYO11_001085"
     CDS             21331..25722
                     /locus_tag="VYO11_001085"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HEV1595670.1"
                     /translation="MSNSFEILMNQLGMPAEMRQAPALAQANIERVVVHKISKVWEFH
                     FVFSNILPIEIFLELKKGLSEEFSKTGNKAVFEIKARSQEFSNQLLQSYYREAFSEGP
                     CASQGFKSLYQNLQVRAEGNQLFIEGSEAIDKEHFKKNHLPNLAKQLEKFGFPTFNCQ
                     VEKNDVLTQEQEEAFHAENEQIVQAANEEALRAMEQLEQMAPPPAEEKPVFDFQAKKA
                     AAKPKLDKAEITPMIEVTTEENRLVFEGVVFDVEQKVTRTGRVLINFKMTDYTSSFSM
                     QKWVKNEEEAQKFDLIKKNSWLRVRGNVEMNNFTRDLTMNVQDLQEVVHYERKDLMPE
                     GERRVEFHAHTNMSTMDALPEVEEIVATAAKWGHKAVAITDHGNVQSFPHGYKAAKKA
                     GIQLIYGMEANIVEDRVPIVYNEVEMDLSEATYVVFDVETTGLSAIYNDLIQVAASKM
                     YKGNVIAEFDEFINPGHPLSAFTTELTGITDDHVKNAKPLEQVLQEFQEFCKDTVLVA
                     HNATFDVGFMNANYERHDLPKISQPVIDTLEFARNLYPEYKRHGLGPLTKRFGVALEH
                     HHMANYDAEATGRLLFIFIKEVAEKHGVTDLARLNIDLISPDSYKKARIKHATIYVKN
                     QVGLKNIFKLVSLSNTKYFEGVPRIPRTVLDAHREGLILGSACSEGEVFDVVVSQGVD
                     AAVEVAKYYDFIEVMPPAIYAPLIAKEQVKDMEELQTIIKSLIEVGDRLGKPVLATGN
                     VHYIEPEEEIYREIIVRSLGQGAMINRTIGHGEHAQPAPLPKAHFRTTNEMLDEFAFL
                     GEELARKLVIENTNALAEIFEPVEVVKGDLYTPFIDKAEETVAELTYKKAFEIYGNPL
                     PDIVDLRIEKELTSILGNGFAVIYLASQMLVQRSNERGYLVGSRGSVGSSFVATMIGI
                     TEVNPLSPHYVCGQCQYSEFITDGSYGSGFDMPHKDCPNCGHKLSKNGQDIPFETFLG
                     FDGDKVPDIDLNFSGEDQPSAHLDVRDIFGEEYAFRAGTVGTVAAKTAYGFVKGYERD
                     YGKFYRDAEVERLAQGAAGVKRTTGQHPGGIVVIPNYMDVYDFTPVQYPADDVTAEWQ
                     TTHFNFHDIDENVLKLDVLGHDDPTMIRKLQDLSGIDPNKIPMDDEGVMALFSGTDVL
                     GVTPEQIGTPTGMLGIPEFGTNFVRGMVDETHPTTFAELLQLSGLSHGTDVWLGNAQD
                     LIKQGIADLSTVIGCRDDIMVYLMHAGLEPKMAFTIMERVRKGLWLKISEEERNGYIE
                     AMKANKVPEWYIESCGKIKYMFPKAHAAAYVMMALRVAYFKVHHPIYYYCAYFSIRAK
                     AFDIKTMGAGLEAIKRRMEEISEKRKNNEASNVEIDLYTTLEIVNEMWERGFKFGKLD
                     LYRSQATEFLIDGDTLIPPFVAMDGLGENVAKQLVRAREEGEFLSKTELRKRGGLSST
                     LVEKMDEMGILGNMPEDNQLSLFDELF"
     gene            25824..26087
                     /locus_tag="VYO11_001086"
     CDS             25824..26087
                     /locus_tag="VYO11_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HEV1595671.1"
                     /translation="MSKMSISIRLDSEVKEQAQQVFSNLGMDMTTAINIFLRQAIQYQ
                     GLPFDVRLDENRKLLQALTDLDQNRNMSQSFESVSDLMEDLRA"
     gene            26080..26358
                     /locus_tag="VYO11_001087"
     CDS             26080..26358
                     /locus_tag="VYO11_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013904578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system YafQ family
                     toxin"
                     /protein_id="HEV1595672.1"
                     /translation="MLKIRYHKQFKKDFKLAMKRGLKAELLEEVLNFLVQEKEHPARY
                     RDHSLTASKHFQGVRECHTQPDWLLVYKVDKSELILNLLRTGSHSDLF"
     gene            26379..26531
                     /locus_tag="VYO11_001088"
     CDS             26379..26531
                     /locus_tag="VYO11_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1595673.1"
                     /translation="MKLRIFAEDKPAKKVFEYQLELADRTILLSTALLSGAIALAGIF
                     SALKEK"
     gene            26553..27794
                     /locus_tag="VYO11_001089"
     CDS             26553..27794
                     /locus_tag="VYO11_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000243957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HEV1595674.1"
                     /translation="MVLPNFKENLEKYAKLLVANGINVQPGHTLALSIDVEQRELAHL
                     IVKEAYALGAHEVIVQWTDDVINREKFLHAPMERLDNVPEYKIAEMNYLLENKASRLG
                     VRSSDPGALNGVDADKLSASAKAMGLAMKPMRIATQSNKVSWTVAAAAGLEWAKKVFP
                     NAASDEEAVDFLWDQIFKTCRVYEADPVKAWEEHAAILKSKADMLNKEQFSALHYTAP
                     GTDLTLGLPKNHVWESAGAVNAQGEEFLPNMPTEEVFTAPDFRRADGYVTSTKPLSYN
                     GNIIEGIKVTFKDGQIVDITAEKGDQVMKDLVFENAGARALGECALVPDPSPISQSGI
                     TFFNTLFDENASNHLAIGAAYATSVVDGAEMSEEELEAAGLNRSDVHVDFMIGSNQMD
                     IDGIREDGTRVPLFRNGNWAN"
     gene            27804..28034
                     /locus_tag="VYO11_001090"
     CDS             27804..28034
                     /locus_tag="VYO11_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000901571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEV1595675.1"
                     /translation="MLGSMFVGLLVGFLAGAMTNRGERMGCFGKMFLGWIGAFLGHLL
                     FGTWGPVLSGTAIIPAILGAMIVLAIFWRRGS"
     gene            28257..28979
                     /locus_tag="VYO11_001091"
     CDS             28257..28979
                     /locus_tag="VYO11_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEV1595676.1"
                     /translation="MRLDKFLVACAVGSRTEVKNLLKAGRVTVNGKKEKSAKLQIDEK
                     IDEIRFDGQVLEYEEFVYYMMNKPKGVISATEDPKHRTVLDLLDDLARSKEVFPVGRL
                     DIDTHGLLLLTNDGQLAHVLLSPKRHVDKTYLAQVKGIMTQEDVETFAEGIPLKDFTC
                     QPAILELVSIDTEKNQSQIRVTIAEGKFHQIKRMVGYCGKEVVDLQRLTMGTLVLDEN
                     LERGEWRRLTKEELEILRANII"
BASE COUNT         8201 a         5461 c         6865 g         8458 t
ORIGIN      
        1 ataatctatt tttattcgca ggtaaaagtt gtagataaac ttactgattc tgaatcgaaa
       61 aaatacggtg aatatattga tttgtacgaa tcgtgtcgtc agaacaattt aagtgttcta
      121 cttaactttc ttcaaaattc ggatgataaa cgaggagtta ttgctagtaa ctcagtgaga
      181 attatgtttg aatctttgga taaagcagac caaattgcgg ccctgaatat ttgtagaaac
      241 tatgtagcac gagaaaatgt tttaaataaa gaagatgcag aaaaattgtt aaatgaaatt
      301 gataaaaaac ttgaaattag cagataggac aattcaaata gagttgagta aaaagtttga
      361 aaagtgaaac aaggagaaag ctatgccagt aaatgaatat ggtcagatga ttggtgagtc
      421 aatggaaggt tatacacccg gtgcactgcc ttctattgat ttcttagaag ggcgttatgc
      481 taggatagag gctctctcgg tagaaaaaca tgcggaggat ttgctagctg tttatggccc
      541 ggatactcct cgggagatgt ggacctatct ttttcaggag ccagtagcag atatggggga
      601 gctggttagc cttttaaatc agatgttggc tcgtaaggac cgtttttact atgcaatcat
      661 agacaaggcg actggtaagg ctttgggaac tttttctctc atgcgcattg accagaataa
      721 ccgagtaata gaagtcggag cagtcacttt ttctccagag ctaaggggta cacggatagg
      781 aactgaggct cagtatctcc tagctcgcta tatttttgag gagctaaact atcgtcgcta
      841 cgagtggaaa tgcgatgcct taaatctgcc atccagacga gttgcggagc gtttgggatt
      901 tgtctatgaa ggaaccttcc gccaggcggt ggtttataag gggcgtacga gagatacgga
      961 ttggttgtct atgattgata tggactggcc tcaagtcaaa gatcgtttgg aaacatggct
     1021 gcgtcctgaa aattttgata aaaatggaca gcagtacaag agcttgagag aactttaaga
     1081 ggtgttgaga tgattactat taaaaagcaa gaaattgtca agctagagga tgttttgcat
     1141 ctctatcagg ctgtcggttg gacaaattat acccatcaac cagagatgct ggagcatgcc
     1201 ttatcgcatt cattagtaat ttatctggca cttgatggtg atgctgtggt gggcttgatt
     1261 cgtttggttg gagatggatt ctcatcagtt tttgtacagg atttgattgt tttaccaatc
     1321 tatcagcgtc aagggattgg tagcgcccta atgaaagagg ccttaaaaga ttacaaagat
     1381 gcttatcaag tccagctggt gacagaagag acagaaaaaa acgtgggatt ttatcgttct
     1441 atgggctttg aaatcttatc cacctataat tgtataggga tgacttgggc gaatcgagaa
     1501 aaataacaaa acttgttttt tcttaagcaa aatttaagga tggtctagta ttatataatc
     1561 attaaataaa gacctcctaa ctttatttaa taaaatccta aacttttctt tttcataata
     1621 atctccctta actccaccca atcaggtgga gttttttagc tctatttcag gcttttgggg
     1681 actattctaa aaataatttt tcgatatttt tcggtatttt tcggattttg gtcggggaat
     1741 tggcggggac ttttttagcg aatataacta agaaataggt ctgtggtcgc ttcagctagt
     1801 tcaaactcaa tttgattgta agtgactgtt aattgaagaa ctggaactac tgtaataatg
     1861 attttgcttg tctagtagtg gcgtattaaa tgagaagtga catgtaagat tgtctcttcg
     1921 tttacgaaat caaaatttct atgaaattga tagaatccct aacgttctct taatcttaac
     1981 cgtcttgtcg tacagcggtt gaagaaaatg taaacctttg acaaaattcg tgaactatgg
     2041 gataataaaa aggaattgag tactagttct atatcatagg ctagaaaaga ccccaagctc
     2101 acgaccaaat aagcttgggg tcttttttga cactatttgt ccttgtttag ccatttatcg
     2161 actatacgaa gaacgacacc gaccacaatt ggtccgatga tagttttgag tactaattcc
     2221 atcatgggct atctcacctc ctttcgtagg cggtgtagca gtgtcgtaga atattatacc
     2281 acataagtgc taaacttagg agtcacccaa tcaggtggct tttttgtttg tggcttggtt
     2341 ttttgatata atagagccat gagtagaatt ttagataatg agataatggg ggatgaggag
     2401 ttagtagaac gcacgctccg tcctcagtat ttacgtgaat atatcggaca ggataaggtc
     2461 aaggaccagc tacaaatctt tattgaagct gccaaaatgc gggatgaagc gctggatcat
     2521 gtgctcttat ttgggcctcc aggtctcggg aaaacgacca tggcctttgt tattgccaac
     2581 gaactgggag tcaatcttaa gcagacgtcg ggtccagtca ttgaaaaagc cggagatctg
     2641 gtagctattt tgaatgagtt agagcctggg gatgtacttt ttattgatga gatccatcgt
     2701 ttgccaatgt cagtggaaga ggtgctttat agtgctatgg aggacttcta catagatatt
     2761 atgattgggg ctggtgaggg tagtcgtagt gttcatttgg agttaccacc ttttaccttg
     2821 attggtgcga cgactcgggc tggtatgctc tccaatccgc tacgggcacg ttttgggatt
     2881 acaggccata tggagtatta tgcccatgct gacttgacag aaattgtcga gcggacggca
     2941 gatatttttg agatggaaat cactcatgag gcagcatctg agttggccct acgtagtcgt
     3001 gggacccctc gtattgccaa tcgtctcctc aagcgcgtgc gcgattttgc ccagataatg
     3061 gggaatgggg taattgatga tattattacc gataaggctt tgactatgct ggatgttgac
     3121 catgaaggtt tggactatgt ggatcaaaaa atccttcgta ccatgattga gatgtacagt
     3181 ggaggacctg ttggtctagg aactctttct gtgaatatcg ccgaagagcg tgagacagtt
     3241 gaagatatgt atgagcctta cttgattcaa aaaggtttta tcatgcggac acggtctgga
     3301 cgggtggcga ctgctaaggc atatgagcac ttaggttatg aatacagtga aaaataagca
     3361 agaaatctta gaggctttta gagaaaatcc agatatgatg gccattctga cgatcatccg
     3421 agaccttggt ctgaaagact cgtggttggc agcaggttct gtcagaaatt tcatttggaa
     3481 tcttttgtca gacaaatccc cttttgatca tgaaacagat atagatgtga ttttctttga
     3541 tccagatttt tcttatgagg aaaccttatt actggagaaa aagctgcgag aggattttcc
     3601 tcagtaccag tgggaattga aaaatcaggt ctatatgcat cagcacagtc ctcacactgc
     3661 ttcctatacc agttctcgtg atgctatgag taagtatcca gaacggtgta cgacagttgg
     3721 actgcgcttg aatgaagaat cagattttga actctatgca ccttatggtt tggaggatat
     3781 tttgaatttt caagttcgtc caactcctca tttcttagaa aatgaagacc gaatggaact
     3841 ctatcaaaca cgtttatcca agaaaaattg gcaggagaaa tggaaaaatt tgatttttaa
     3901 aaatacttaa ggaaacttta agctagggag tgtacactaa gttcataagt taagaagacc
     3961 ttaacttaaa ctcctaaaac tttttcataa taatctccct ataaaaataa agtcgcccaa
     4021 tcaggcggct tatttttttg aaaaatgggc ttggtgcctg agaataaata gcttagtgat
     4081 agaagaaaat ggggaaatat ggtataatga aacgatagat ttttgaatag gaataagatc
     4141 atgtttggat tttttaagaa agataaggct gtggaagtag aggttccgac acaggttcct
     4201 gctcatatcg gcatcatcat ggatggcaat ggccgttggg ctaaaaaacg tatgcaaccg
     4261 cgagtttttg gacacaaggc gggcatggaa gcattgcaaa ccgtgaccaa ggcagccaac
     4321 aaactgggcg tcaaggttat tacggtctat gctttttcta cggaaaactg gacccgtcca
     4381 gatcaggaag tcaagtttat catgaacttg ccagtagagt tttatgataa ttatgtcccg
     4441 gaactacatg cgaataatgt taagattcaa atgattgggg agacagaccg cctgcctaag
     4501 caaacctttg aagctttaac caaggctgag gaattgacta agaacaacac aggattgatt
     4561 cttaattttg ctcttaacta tggtggacgt gctgagatta cacaggcgct taagttgatt
     4621 tcccaggatg ttttagatgc caaaatcaac ccaggtgaca tcacagagga attgattggt
     4681 aactatctct ttactcagca tttgcctaag gacttacgag acccagactt gattatccgt
     4741 actagtggag aattacgttt gagcaatttc cttccatggc agggagccta tagtgagctt
     4801 tattttacgg acaccttatg gcctgatttt gacgaagcgg ccttgcagga agctattctt
     4861 gcctataatc gtcgtcatcg ccgatttgga ggagtttagg aggaaatatg acccaggatt
     4921 tacagaaaag aaccttgttt gcagggattg ccctggctat tttcctacca attttaatga
     4981 ttgggggcct cttgcttcag atagcaatcg gaatcatagc catgctagcc atgcatgaac
     5041 ttttgaagat gagaggtcta gagaccatga cgatggaggg cctcttgacc ctctttgcaa
     5101 cctttgcatt gaccattccc ttggagaatt acctgacttt tttgccagtt gatgggaatg
     5161 tggttgccta tagtgttttg atttcaatca tgttaggaac gaccgttttt agcaagtctt
     5221 atacgattga ggatgcggtt ttccctcttg ctatgagctt ctacgtgggc tttggattta
     5281 atgctttact agatgctcgt gttgcaggtt tggacaaggc tctcttagcc ttgtgtatcg
     5341 tctgggcgac agacagtggt gcctatcttg ttgggatgaa ctatgggaaa cgaaagttag
     5401 caccaagggt atcgcctaat aaaacccttg agggtgcctt gggtggtatt ttaggagcaa
     5461 ttttagtaac cattatcttt atgatagttg acagtacagt tgctcttcca tatggaattt
     5521 acaagatgtc agtctttgct attttcttta gcattgctgg acaatttggt gatttactag
     5581 aaagttcgat caaacgtcat tttggtgtta aggattctgg gaaatttatc cctggacatg
     5641 gtggtgtttt ggatcgtttc gatagtatgt tgcttgtatt tccaatcatg cacttatttg
     5701 gactctttta atcaaaagac ggaggaaaca ctatgcttgg aattttaacc tttattctgg
     5761 tttttgggat tattgtagtg gtgcacgagt tcgggcactt ctactttgcc aagaaatcag
     5821 ggattttagt acgtgaattt gccatcggta tgggacctaa aatctttgct cacattggca
     5881 aggatggaac ggcctatacc attcgaatct tgcctctggg tggctatgtc cgcatggccg
     5941 gttggggtga tgatacaact gaaatcaaga caggaacgcc tgttagtttg acacttgctg
     6001 atgatggtaa ggttaaacgc atcaatctct caggtaaaaa attggatcaa acagccctcc
     6061 ctatgcaggt gacccagttt gattttgaag acaagctctt tatcaaagga ttggttctgg
     6121 aagaagaaaa aacatttgca gtggatcacg atgcaacggt tgtggaagca gatggtactg
     6181 aggttcggat tgcaccttta gatgttcaat atcaaaatgc gactatctgg ggcaaactga
     6241 ttaccaattt tgcaggccct atgaacaatt ttatcttagg tgtcgttgtt ttttgggttt
     6301 taatctttat gcagggtggt gtcagagatg ttgataccaa tcagttccat atcatgcccc
     6361 aaggtgcctt ggccaaggta ggagtaccag aaacgtcaca aattactaag attggctcac
     6421 atgaggttag caactgggaa agcttgatcc aagctgtgga aacagaaacc aaagataaga
     6481 cggcaccgac tttggatgtg actatttctg aaaaggggag tgacaaacaa gtcactgtta
     6541 cacccgaaga tagtcaaggt cgttaccttc taggtgttca accgggggtt aagtcagatt
     6601 ttctatccat gtttgtaggt ggttttacaa ctgctgctga ctcagctctc cgaattctct
     6661 cagctctgaa aaatctgatt ttccaaccgg atttgaacaa gttgggtgga cctgttgcta
     6721 tctttaaggc aagtagtgat gctgctagaa atggaattga gaatgtcttg tacttcttgg
     6781 caatgatttc catcaatatt gggattttta atcttattcc gattccagcc ttggatggtg
     6841 gtaagattgt gctcaatatc ctagaagcca tccgccgcaa accattgaaa caagaaattg
     6901 aaacctatgt caccttggcc ggagtggtca tcatggttgt cttgatgatt gctgtgactt
     6961 ggaatgacat tatgcgactc ttttttagat aatcgaggaa tattatgaaa caaagtaaaa
     7021 tgcctatccc aacgcttcgc gaaatgccaa gcgatgctca agttatcagc catgctctta
     7081 tgttgcgtgc tggttatgtt cgccaagttt cagcaggtgt ttattcttat ctaccacttg
     7141 ccaaccgtgt gattgaaaaa gctaaaaaca tcatgcgcca agaattcgaa aagattggtg
     7201 ctgttgagat gttggctcca gcccttctta gtgcagaatt gtggcgtgaa tcaggtcgtt
     7261 acgaaaccta tggtgaagac ctttacaaac tgaaaaaccg tgaaaaatca gactttatct
     7321 taggtccaac tcacgaagaa acctttacag ctattgtccg tgattctgtt aaatcttaca
     7381 agcaattgcc actcaacctt tatcaaattc agcccaagta tcgtgatgaa aaacgcccac
     7441 gtaatggact tcttcgtaca cgtgagttta tcatgaagga tgcttatagt ttccacgcta
     7501 actatgatag tttggatagt gtttatgatg agtacaaagc agcctatgag cgtattttca
     7561 ctcgtagtgg tttagacttc aaggctatta ttggtgacgg tggagccatg ggtggtaagg
     7621 atagccaaga atttatggcc attacatctg ctcgtacaga ccttgaccgc tgggttgtct
     7681 tggacaagtc agttgtctca tttgacgaaa ttcctgcaga agtgcaagaa gaaatcaagg
     7741 cagaattgct caaatggata gtctctggtg aagataccat tgcttactca agtgagtcta
     7801 gctatgcagc taacttagaa atggcaacaa acgagtacaa accaagcaac cgtgttgtcg
     7861 ctgaagaaga agttactcgt gttgcaacgc cagatgttaa atcaattgat gaagttgcag
     7921 ccttcctcaa tgttccagaa gaacaaacga ttaaaaccct cttctacatt gcagatggcg
     7981 agcttgttgc agcccttcta gttggaaatg accaactcaa cgaagtcaag ttgaaaaatc
     8041 acttgggagc agatttcttt gacgttgcta gcgaagaaga agtggcgaat gttgttcaag
     8101 caggatttgg ttcacttgga ccagttggtt tgccagagaa tattaaaatt attgcagatc
     8161 gtaaggtaca agatgttcgc aatgcagttg tcggtgctaa cgaagatggc taccacttga
     8221 ctggtgtgaa cccaggccgt gattttactg cagaatatgt ggatatccgt gaagttcgtg
     8281 agggtgaaat ttccccagat ggacaaggtg tccttaactt tgcgcgtggt attgagatcg
     8341 gtcatatttt caaactcgga actcgctatt cagcaagcat gggagcagat gtcttggatg
     8401 aaaatggtcg tgctgtgcca atcatcatgg gatgttacgg tatcggtgtc agccgtcttc
     8461 tttcagcagt gatggagcaa cacgctcgcc tctttgttaa caaaacgcca aaaggtgaat
     8521 accgttacgc ttggggaatc aatttcccta aagaattggc accatttgat gtgcatttga
     8581 ttactgtcaa tgtcaaggat gaagaagcgc aagccttgac agaaaaactt gaagcaagct
     8641 tgatgggagc tggttatgaa gtcttgacag atgaccgtaa cgaacgtgtc ggtgttaaat
     8701 ttagcgatag tgacttgatt ggtcttccaa tccgtatcac tgttggtaaa aaagcggccg
     8761 atggcattgt agaagttaag atcaaggcaa ctggtgacac cattgaggtt catgcagata
     8821 acgtgcttga aacgcttgaa atcctaagca agaaataaaa actataatca gaagaaaaac
     8881 aaggaaaaaa tgtaactagt ttttaccttg ttttttctgt ataatgggag aaatgagtag
     8941 ataaagaggt aaatgtatgc taagatttcc aaaggatttt gtctggggat cctctacttc
     9001 tggaccgcag acagaaggac gtgtagctgg tgacggtaag ggagacaatc tctgggatta
     9061 ctggttccaa gtggagccaa atcgttacta taatgggatt ggttcagata agacatcgac
     9121 tttttatgaa aattgggagc gggatattga gcttttgtta gagactggtc acacagcctt
     9181 tcggacttct attcagtggt cacggatttt tccacaaggc tgtggaaaag tcaacactca
     9241 aggtgtggat ttttatcgta aggtctttga ggctattaag gctaaaggaa ttcgtctgtt
     9301 agtcaatctc tatcattttg atttaccttt tgcccttcaa gaggatggtg atggttggga
     9361 aaataaggcg acagtctcag cctatgaaga ctatgctcgt ttttgttttg agacttatgg
     9421 agatttagtg gatcaatgga ttacctttaa cgagcccatc gttcctgtag aatttggtta
     9481 tttttatgat gcccattatc cacataaggt ggatgcagag gcagctgtta aggtagccta
     9541 tcatacacaa ttggccagca gccgggctgt taaggcttgc catgaacttt tgcctgattc
     9601 caagattggg attgtcctca acttgacacc ggcttatcca cgtagccagc atcctgctga
     9661 tgtcaaggca gctcgtattg cggccctttt tcaggcccaa tctttcttag atccatctgt
     9721 cttggggact tatccacagg agttggtaga aatcttgcat gaacacggtc ttttacctga
     9781 tgctacagag gaagagttgg aactcattcg tgataatacg gtggacttcc ttggtgtgaa
     9841 ctactatcaa cctttgcgtg ttatggctcc tcgatttgct aagcatccag agagtccact
     9901 cttaccagaa catttttacg agccttatgt gatgcctgga cgtaaaatca attctcatcg
     9961 tggttgggag atttatgagc aagggattta tgacatcgcc caaaatatca aggaaaatta
    10021 tggcaatatt gagtggatgt tgactgagaa tggtatgggt gttgaagggg aagaaaaatt
    10081 ccgtcaagat ggaatgattc aagatgatta ccgtattgac tttgtaaaag gtcatcttcg
    10141 tgaacttcac cgtgccattg aagatggtgc caactgtaag ggctacttga tttggacctt
    10201 tattgactgc tggtcatggc tcaacagcta taaaaatcgc tatggtttgg tcgaattaga
    10261 cttggaaacg caagaacgtc gtctgaagaa atcaggccac tggttcaaga aactaagcga
    10321 caataatgga ttttaaaaag gactctgact gattatccca atcggtcaga gttttttgct
    10381 tacaggagct taatttgaac tataccaatt tttactcttg acaagtgaaa gaaacaagta
    10441 tatactgttt ttgctgattc tataaaagat gaattagact ataccaattt taaggagaaa
    10501 gcacagcttg cctgtgtcgt atatactatg tgtggaattg ttggtgttgt tggaaacaca
    10561 aatgcaactg atattttgat tcaagggctt gaaaagcttg aataccgtgg ctatgattct
    10621 gcgggaattt ttgtcctaga tggtgctgat aaccatttgg tgaaggcggt tggtcgtatt
    10681 gcagaattgt ctgccaagac agctggtgtt gagggaacaa ctggtatcgg acatactcgt
    10741 tgggctactc acggaaaacc aactgaggac aatgctcacc cacaccgctc tgagacagaa
    10801 cgttttgtct tggtgcataa tggggtgatt gagaactatc ttgaaatcaa ggaagaatac
    10861 cttgcaggtc accacttcaa ggggcagaca gatactgaaa tagccgttca tttgattgga
    10921 aaatttgcgg aagaagaagg gctctcagtt cttgaagcct tcaaaaaagc ccttcacatc
    10981 atccgtggtt cttatgcctt tgccttggtt gactcacaag atcctgaagt catctacgta
    11041 gctaaaaata aatcaccact tttgattggt cttggagaag gctataacat ggtctgctca
    11101 gacgccatgg ctatgattcg tgaaactaac caatacatgg aaatccatga ccaagagttg
    11161 gtaatcgtca aggctgatag tgtggaagtt caagactatg atggaaatcg tcgtgagcgt
    11221 gctagctaca ctgctgaact tgacttgtca gatatcggta agggaactta cccttactac
    11281 atgctcaagg aaattgacga gcaaccaact gttatgcgta aactcattca agcctacacg
    11341 gatgatgctg gtcaagtagt ggttgatcct gctatcatta aggctgttca agacgcagac
    11401 cgcatctaca tccttgcagc tggaacatct taccatgcag gatttgcttc taagaaaatg
    11461 ttggaagaat tgacagatac accagttgaa cttggcatct catctgagtg gggctacggt
    11521 atgccacttc tcagcaagaa accactcttc atctttatca gccaatctgg tgaaacagcg
    11581 gatagtcgtc aagttttggt caaggctaat gaaatgggaa ttccaagctt aacagtgaca
    11641 aatgttccag gctcaaccct ctcacgtgaa gccaactata ccatgctcct tcacgcaggt
    11701 cctgaaattg ccgtggcatc aactaaagcc tatacagcgc aaatcgcagc ccttgccttc
    11761 cttgcaaaag cagtcggaga agcaaatggt aatgctaaag cgcaagcctt tgacctgatt
    11821 catgaattgt caatcgtagc tcagtctatc gaatcaactc tttcagagaa agaaaccatt
    11881 gaagccaagg ttcgtgaact tcttgaaaca actcgtaacg ccttttacat cggacgtggt
    11941 caagattact acgtagccat ggaagcaagt ctcaaactca aagagatttc ttatatccag
    12001 tgtgaaggct ttgctgcagg agaactcaag cacggaacca ttgccttgat tgaagaagga
    12061 acgcctgttt tggctctctt gtcagatcca gttcttgcca atcatactcg tggaaatatc
    12121 caagaggtcg cagcccgtgg tgccaaagtc ctcactatcg cagaagagaa tgtagccaaa
    12181 gataccgacg atatcgtcct tacgaccgta catccatacc tctcaccaat ttcaatggtc
    12241 gtaccaacgc aattagtcgc ttactttgca accctccacc gtggcctcga tgtggataaa
    12301 ccacgtaacc ttgctaaatc agtaacggta gaataagcta aaaaagtcta gttatctagg
    12361 ctttttctaa tgagcaaatt ggttgcttgt acttaagatt cgtgttagaa taatttttca
    12421 aattgaagga cagagataga caaggagaat cacaatggta gaattgggaa tttcaacatt
    12481 tggggaaata acggagcttg aagggactgg acaaacttac agtcatgctg aacgcattcg
    12541 ccagttggtg gcagagattg agctggctga caaggttggt ttggacgtat atgggattgg
    12601 cgagcaccat cgggcggatt ttgcagtatc agccccagag attgtcctgg ccgctggggc
    12661 agtcaatacc aagaaaatcc gtttgaccag cgcagtcagc attctgtcaa gcatggaccc
    12721 gattcgtttg ttccaacagt atgccactat cgatgctttg tcaaatggac gagcggagat
    12781 tatggctgga aggggctctt tcacggaatc tttccctctg tttggttatg acttgaaaga
    12841 ctacgactct ctttttgatg agaaattaga cttgcttcag ttagtcaatg aaaagaccaa
    12901 gttagactgg caaggtcgat tgactcaaac gattgctggt aaagaagttt atcctcgtcc
    12961 agttcaggac aaattgccct tgtggatagc tacaggtggt catgtcgaat caacagtgaa
    13021 gattgctcag gctggtctac cgattgtata tgctattatt gatggtaatc cacgttattt
    13081 taaaaagttg attcaggctt atcgtgagat tggaagcgaa gcgggccatg ctgacaaaga
    13141 cttgaaagtg ggagcccatt cttgggggtg gattgcggaa gatggtgagc aggcggtgaa
    13201 agattatttc catccgacta agcaagtggt ggatgctatt tccaaagacc gtccgcactg
    13261 gcaggaattg cgttatgagc aatatttgga tcaggtaggg tcaaatggcg ccatgtttgt
    13321 tggcaatcca gatcaggtgg ccgaaaaatt gattcgcatg atagaggatt taggattgga
    13381 ccgcttcatg cttcatctac cgcttggttc tatgcctcat gaccaggttc tgagagctat
    13441 tgaactcttc ggaacacaag ttgcacccaa agtacgagct tattttgcta tgaaagaggc
    13501 ttaataaaaa atcctaatca agtttattag gacaacaaat attgtacgaa aattaatccc
    13561 ccgagctata atgcttgggg gatttttcta taggagggct agtttagttc tcttttttat
    13621 tttttagtaa gaaaccgaga ccaaggagcg caaggaggct gattcctgca aataggagtt
    13681 tgttttcgtt tttgattcct gtatttggaa gttcagcttg tctatctggg gttgcaggta
    13741 tatttttctt gctagagttt tctaccgatt cgttttgaac cgcttctttt acagatgatg
    13801 cttgtgcttc ttgtgctggt tgttcagctt gtgaatcagc tgtagcttgg ctaggtttat
    13861 tttccgcatc agctactttg gcatctggtt tagtagaatc aggtctagct tctggagctg
    13921 ggtcttgata tgcagggtga gaagcttcat tttgatgttc aggcttggaa gggattgagt
    13981 ctggtttctc ttctgcagtt gactcatggc tagttccatt ttgagagact cgaagaacag
    14041 tagctgtaag ggcattcaat ttcaagcctt tttcagtcca ttcaagtcct ttcgggttgg
    14101 caatttcgac tgatcctgct tggttttcat ctgccaaaac ttccgcattt cttagatgtg
    14161 caaaggcagt tcccaaatta aattcgcgag ctttttcatc cgcattgaca aagactgcgt
    14221 agatatcgcc gtttggagca gtgatttggt agccaatcac tacatcctct ttttccacac
    14281 cattttggcc tgggacagtg atgaggtgga cacggtcttt gatatcttga agactcttaa
    14341 gtcggaaggc atctgtagat tgacgaaggg caatcaaacc tttcatatag tcacggctct
    14401 tgacattttc aggataagct ttaccatctg tagccttagt ccagtcaaac ttgttgactg
    14461 catcgctaga atcgtaagaa tcatggatga agtaaggata gtcaaatggg ttgccgtcct
    14521 tatcacgcaa caagtgagat ttgtttggaa ccttatcctc tgctactgga gtcttgtagg
    14581 ctgggtcacg gaattgttta gtacgtccat attcctgacc ggagtggata aatggagttc
    14641 cttgagctgt caagaccatg agatttccaa gtcgtaaacg acggtggatt tcagcatagt
    14701 tctcagcctt gcttgggtct tttttgatag actgggcaat gatgtcaaag agggtcaagt
    14761 tatcatgggc tgctatgtat tggatgacat ctccagggct gtcagcttca aagttagttg
    14821 gttgagcaat gagattttta aagatggtgt tgacatcacg cttgccacct gtgataaagg
    14881 caggttgacc ttcgtttgga taaccagatt tgaggttgtt acggatgtca tctgaaaaga
    14941 cagcgacagt atcggtatgt ttcatccaat cttggtcagc agctttagta ggcatgtttt
    15001 catcaccggc ataggttctc caaccttcac caagcatgat gaggtttgga ttgagggcgc
    15061 gtgcagcctt gtaagcttct tcgatagaag cggcgtcatg gtctcccatc atatcgaagc
    15121 ggaagccatc cactttgtag gtatcaacta ggtatttgat agagtcaact aggagccgtt
    15181 tggtcatatg gtgggttgtc cccaagcgtc caccaccaaa gctagttcga ggtgtgccat
    15241 ctgcatccat aaagtggtag tagtttggct ctaggtcttc aaagatatcg actttggctg
    15301 tgtggttata aacgacatct aggatagctc ccataccacg tttgtggatt tcgttgatga
    15361 ggtttttaaa ttctgcgatt cgtttttctg gattcttagg atcgcttgag tacataccag
    15421 tcaaggagaa gtagttttga gggtcatatc cccagttgta gttgctgttg cttgaagcgt
    15481 agtcagacaa gcgttcatgg tttttcaatt cattgacaaa gtagtaagac aagactggaa
    15541 ggagctggat atgggttaca cccaagtctt tgagatagtc tagtttttca atgaaggctt
    15601 caaaagtccc aaatggtttg gtcaagtctt ttgcaatggc aggatctgaa gtgaagtcac
    15661 gcacatgagc ttcgtagata acggcgtctt cacgagtctt gaaattgtga atcttaccat
    15721 aagtcaagtc ttgaggtccg agtttagctg gatctacaaa ggcggcttta gccactttat
    15781 gggcatcgtc aatcttggca tcgtcgctat tccaagcagc aagagattta gcgtaaggat
    15841 cgagtgcaag aacagtttta ccttgacgct cgatttggta ttgataatag tatccagtga
    15901 aatctgtgat tccgagtttg tttgtgctgt ctagagtttg tttccaagtt cctctttccc
    15961 ctttttcaag agcgacagtt ccaactactt tgtcagggtc attcttgtcg tagacaacaa
    16021 cagaaacctt atcagcactt ggtgaccaaa gggtcaaatc aacttgtttt ccttcttctt
    16081 ttaggtcagc tcccagtttg ccatcatagc tgtatgtctc atctttcagg cgccagcttg
    16141 ttttggtagt gaattggtcg gaattgtagc taacagtata aggatgtttt gtgtcagaga
    16201 aatctccgct gtaggtcact ttcttaccag cttcatcgat tgcaacatcg gtaatagtta
    16261 ccttgtttcc taggtgatta gtgatgttgg agtgtttgag gatatcttct tttttagcac
    16321 cgacaagtgt tgaaaagcta ctttcaatgc tagaagtgcc tacgtgttgg gctcctgtca
    16381 tacggatatc atggacatag tatggatttg tgtaaatcga ttcatcatcg tcttttagga
    16441 aaatttggct atgatttttc aaatctgtga acttataatt ttctttacgg attttcacgt
    16501 cgtctccttg tttgctctca tctagtaata aaaatccaaa ttctcttgcg gcttcattaa
    16561 gaggaatgtc gatatagcgg ccatatttgc ctgtagccgt aaagtctgtt ccgtcaggcc
    16621 attgagcgct acttggattt tttacatctc cccagtacca gagagatttc ttgtcatagt
    16681 tgccatctgt gcggtagtag ttgacgcgaa cagttcctgc aggctgtggc tcgtaagaga
    16741 aaaccttgta atcttggtct aaccaagcct cgttcatttt tggaactagt ttttctacag
    16801 atttatcgcc ggttagattt tttccagctg tattgttgat gaggaagcta attttcttgg
    16861 cttgttctcc ctttaatttg acatctaggt aatagccgta gtcatctttc ttggcatcct
    16921 tgaaggacaa agctccgttt ggccagtttt cagatggttt ttcaacatcg tcccaagtcc
    16981 atagtccttg agcatccttg ttttcttcag gaagtttttt gacatggata cggaagtagt
    17041 tatcttcgat gggctcttct gccttagttt cagttgttac tggactagta gaagtagttg
    17101 gctctgttgc aggtttttct tctgttttct ctagggaagc gtttgcattt ctaggtgaag
    17161 aaatatcact ttcgttctta ccagagccag ctgctgtatc agtaagaggt tgggcaaggg
    17221 tggttgtatt tctgttgttg ggttcgttag tggttggtgt actttcgtcg gatgagatag
    17281 ttggtgtagc catggcaagc aagacaaggc ttgcgccgat aaggacagaa ccagttccat
    17341 ttttgaggga acggatgctg tagaccattt ttttctcagt gtgagatggt gtttttctca
    17401 taatgattct ccaatcaata aatttctata tcagtatagc atgtagtaaa ataatatgca
    17461 agcgttttct ttgatttgtg aaaaaaattc ttacttttga gaagttttct gtactatttt
    17521 atatatcagt ataaatgacg gagataaaaa tgtcacataa gccaagccgt attattagga
    17581 agatgatgtg ttcccagcta tttttattca gaaattgatc tctaacatta ccaataaaaa
    17641 tgaaaaatat cttgacaagc aagggaaaat tttgttacaa tgatagacgg tactttttac
    17701 ttttggtctc tcaagagtgt acagggacgt gctgacaaat gttgcaaaag tacacacaga
    17761 tgatatctgt caccaagtgt atcatcacca aaaataaaaa aacacaggag aatgtagatg
    17821 cctacaatta accaattggt tcgcaaaccg cgtaaatcaa aagtagaaaa atctaaatca
    17881 ccagctttga acgttggtta caatagtcat aaaaaagttc aaacaaacgt ttcttcacca
    17941 caaaaacgtg gtgttgcaac tcgtgttgga acaatgacac ctaaaaaacc taactcagcc
    18001 cttcgtaaat tcgctcgtgt acgtttgagc aaccttatcg aagttactgc ctacatccca
    18061 ggtatcggac acaacttgca agagcacagc gtggtgcttc ttcgcggtgg acgtgtaaaa
    18121 gaccttccag gggtacgtta ccatatcgtc cgtggtgcac ttgatactgc aggtgttaac
    18181 gatcgtaaac aaggccgttc taaatacggt actaaacgtc caaaagcata aggaaagggg
    18241 ataaagagaa atgagtcgta aaaatagagc tccaaaacgt gacgtattgc cagatccgct
    18301 atacaattca caactagtta ctcgtcttat caaccgcgtt atgcttgatg gtaaacgtgg
    18361 tactgctgct tcaatcgttt acggtgcttt tgagcaaatc aaagaagcta ctggcaacga
    18421 tgcacttgaa gtatttgaaa cagctatgga aaacatcatg cctgtacttg aagtacgtgc
    18481 acgtcgtgtt ggtggttcta actaccaagt cccagttgaa gttcgtccag aacgtcgtac
    18541 aacacttgga cttcgttggt tggtaacaat cgctcgtctt cgtggtgaac acacaatgca
    18601 agaccgtctt gcaaaagaaa tcttggatgc tgctaacaac actggtgcag ctgttaagaa
    18661 acgtgaagat actcaccgta tggctgaagc taaccgtgca ttcgcacact tccgttggta
    18721 agataggatg cgaaagcgtt aagaaagtcc cagagaaaat agggaatcga agcaggttgc
    18781 ggttgcaacc aatgagattc atctttttct ccagactttt agcttgagct caactaaatc
    18841 atgatgctag gcacggtaag gatgcaaggt gaaaatagga aactgacgca gtattcaacg
    18901 aatacaagga gttttatctt tttcacgcag catcccgttc cagctcacat cggctaacta
    18961 actttagccc gggttcaaat tagctaaatc gattagtatt agctataact cagcttacca
    19021 tctagtaagt tgaaaccaac aatagcatga aaacattgag aacgggtagg tcctgcctat
    19081 ccgtttttat taaaatcgtg ttataataga atagaaatca aaaataaata ggagaaacaa
    19141 acctcatggc acgcgaattt tcacttgaaa aaactcgtaa tatcggtatc atggctcacg
    19201 tcgatgccgg taaaacaaca actactgagc gtattcttta ctacactggt aaaatccaca
    19261 aaatcggtga aactcacgaa ggtgcgtcac aaatggactg gatggagcaa gagcaagaac
    19321 gtggtatcac gatcacatct gctgcgacaa cagctcaatg gaacaaccac cgcgtaaaca
    19381 tcatcgacac accaggacac gtggacttca caatcgaagt acaacgttct cttcgtgtat
    19441 tggatggtgc ggttaccgtt cttgactcac aatcaggtgt tgaacctcaa actgaaacag
    19501 tttggcgtca agcaactgag tacggagttc cacgtatcgt atttgccaac aaaatggaca
    19561 aaatcggtgc tgacttcctt tactctgtaa gcacacttca cgatcgtctt caagcaaatg
    19621 cacacccaat ccaattgcca atcggttctg aagatgactt ccgtggtatc attgacttga
    19681 tcaagatgaa agctgaaatc tatactaacg accttggtac ggatatcctt gaagaagaca
    19741 tcccagctga ataccttgac caagctcaag aataccgtga aaaattgatt gaagcagttg
    19801 ctgaaactga cgaagaattg atgatgaaat acctcgaagg tgaagaaatc actaacgaag
    19861 aattgaaagc tggtatccgt aaagcgacta tcaacgttga attctttcca gtattgtgtg
    19921 gttcagcctt caaaaacaaa ggtgttcaat tgatgcttga tgcggttatc gactaccttc
    19981 caagcccact tgacatccca gcaatcaaag gtattaaccc agatacagac gctgaagaaa
    20041 ctcgtccagc atctgacgaa gagccatttg cagctcttgc cttcaagatc atgactgacc
    20101 cattcgtagg tcgtttgaca ttcttccgtg tttactcagg tgttcttcaa tcaggttcat
    20161 acgtattgaa tacttctaaa ggtaaacgtg aacgtatcgg acgtatcctt caaatgcacg
    20221 ctaacagccg tcaagaaatc gacactgttt actcaggtga tatcgctgct gccgttggtt
    20281 tgaaagatac tacaactggt gactcattga cagatgaaaa atctaaaatc atccttgagt
    20341 caatcaacgt tccagaacca gttatccaat tgatggttga gccaaaatct aaagctgacc
    20401 aagacaagat gggtatcgcc cttcaaaaat tggctgaaga agatccaaca ttccgcgttg
    20461 aaacaaacgt tgaaactggt gaaacagtta tctcaggtat gggtgaactt caccttgacg
    20521 tccttgttga tcgtatgcgt cgtgagttca aagttgaagc gaacgtaggt gctcctcaag
    20581 tatcttaccg tgaaacattc cgcgcttcta cccaagcacg tggattcttc aaacgtcagt
    20641 ctggtggtaa aggtcaattc ggtgatgtgt ggattgaatt tactccaaac gaagaaggta
    20701 aaggattcga attcgaaaac gcaatcgtcg gtggtgtggt tcctcgtgaa tttatcccag
    20761 cggttgaaaa aggtttggta gaatctatgg ctaacggtgt tcttgcaggt tacccaatgg
    20821 ttgacgttaa agctaagctt tatgatggtt catatcacga tgtcgactca tctgaaactg
    20881 ccttcaagat tgcggcttca ctttccctta aagaagctgc taaatcagca caaccagcta
    20941 tccttgaacc aatgatgctt gtaacaatca ctgttccaga agaaaacctt ggtgatgtta
    21001 tgggtcacgt aactgctcgt cgtggacgtg tagatggtat ggaagcacac ggtaacagcc
    21061 aaatcgttcg tgcttacgtt ccacttgctg aaatgttcgg ttacgcaaca gttcttcgtt
    21121 ctgcatctca aggacgtggt acattcatga tggtatttga ccactacgaa gatgtaccta
    21181 agtcagtaca agaagaaatt attaagaaaa ataaaggtga agactaatcc gtcctcactc
    21241 tagaaggaag tcacttagtg gcttcctttt gtctttagaa aatacctcta aatatggtaa
    21301 aatagtagaa gaataatgtg aggaaaatga atgtcaaata gttttgaaat tttgatgaat
    21361 caattgggga tgcctgctga aatgagacag gctcctgctt tagcacaggc caatattgag
    21421 cgagttgtgg ttcataaaat tagtaaggta tgggagtttc atttcgtatt ttctaatatt
    21481 ttaccgattg aaatcttttt agaattaaag aaaggtttga gcgaagaatt ttctaagaca
    21541 ggcaataaag ctgtttttga aattaaggct cggtctcaag aattttcaaa tcagctcttg
    21601 cagtcctact atagggaggc tttctctgaa ggtccatgtg ctagtcaagg ttttaagtcc
    21661 ctttatcaaa atttgcaagt tcgtgctgag ggtaatcagc tatttattga aggatctgaa
    21721 gcgattgata aggaacattt taagaagaat catcttccta atttagccaa acaacttgaa
    21781 aagtttggtt ttccaacttt taactgtcaa gtcgagaaga atgatgtcct gacccaagag
    21841 caggaagagg cctttcatgc tgaaaatgag cagattgttc aagctgccaa tgaggaagcg
    21901 ctccgtgcta tggaacaact ggagcagatg gcacctcctc cagcggaaga gaaaccagtc
    21961 tttgattttc aagcgaaaaa agctgcagct aaacccaagc tggataaggc ggagattact
    22021 cctatgatcg aagtgacgac agaggaaaat cgtctggtat ttgaaggggt tgtttttgat
    22081 gtggagcaaa aagtgactag aacaggtcgt gttttaatca actttaaaat gacggactat
    22141 acttcaagtt tttctatgca aaagtgggtt aaaaacgagg aagaggccca gaagtttgac
    22201 ctcatcaaga agaattcttg gctccgagtt cgagggaatg tggagatgaa taacttcaca
    22261 cgcgatttga ctatgaacgt acaggatctg caggaagttg ttcactatga gcggaaggat
    22321 ttgatgccag aaggtgagcg tcgggttgag tttcatgctc atactaacat gtcgactatg
    22381 gatgctttgc cagaggtcga agagattgtt gcaacagctg ctaagtgggg acacaaggcg
    22441 gttgctatca cagaccatgg gaatgtccag tcctttccac atggctataa ggcggctaag
    22501 aaagcgggaa tccagctgat ctatgggatg gaagccaata tcgtggagga ccgtgtccct
    22561 atcgtctata acgaagtgga gatggactta tcagaagcaa cctacgtggt ctttgacgtg
    22621 gaaacgacgg gactttcagc tatctataat gacttgattc aggttgcggc ctctaagatg
    22681 tacaagggga atgttattgc tgaatttgat gaatttatca atcctgggca tcccttgtca
    22741 gcttttacta cagagttaac tggaattaca gatgatcatg tcaaaaatgc caaaccacta
    22801 gaacaagttt tgcaagaatt ccaagaattt tgcaaggata cggtcctagt tgcccacaat
    22861 gctacctttg acgttggctt tatgaatgct aattatgagc gtcatgatct tccaaagatt
    22921 agtcagccag ttattgatac gctggagttt gctagaaacc tctatcctga gtataaacgc
    22981 catggtttgg ggcctttgac caagcgtttt ggtgtggcct tggaacatca ccacatggcc
    23041 aactacgatg cggaagcgac tggtcgtctg cttttcatct ttatcaaaga ggtagcagaa
    23101 aaacatggtg tgaccgattt agctagactc aacattgatc taatcagtcc agattcttac
    23161 aaaaaagctc ggatcaagca tgcgaccatc tatgtcaaga atcaggtagg tctaaaaaat
    23221 atctttaagc tggtttcctt gtctaatacc aagtattttg aaggagtgcc acggattccg
    23281 agaacggttc tagatgccca tcgagagggc ttgattttag gttcagcctg ttcagagggt
    23341 gaagtttttg acgtggtcgt ttctcaaggt gtggatgcgg cggttgaggt ggccaagtat
    23401 tatgacttta tcgaggtcat gccaccggct atctatgcgc ccttgattgc caaagagcag
    23461 gtcaaggata tggaggaact ccagaccatt atcaagagtt tgatagaggt tggagatcgc
    23521 cttggcaagc ctgttctggc tacgggaaat gttcactata tcgaaccgga agaagagatt
    23581 tatcgtgaaa ttatcgtccg tagtttggga cagggtgcga tgattaaccg aactatcggt
    23641 catggtgaac atgcccaacc agcgccactt ccaaaggctc attttcgaac gactaatgag
    23701 atgttggatg aatttgcctt tttgggagag gaactggctc gtaaactggt tattgaaaac
    23761 accaatgcct tggcagaaat atttgaaccc gttgaagtcg ttaagggtga cttgtatacg
    23821 cctttcatcg acaaggctga agaaacagtt gctgagttga cctataagaa agcttttgag
    23881 atttatggaa atccgctgcc agatattgtt gatttgcgga ttgaaaaaga attaacatcc
    23941 atactgggga atggatttgc tgtgatttat ctggcatcgc agatgctggt gcaacgttct
    24001 aatgaacggg gttatttggt tggttctcgt gggtctgtcg gatctagttt cgttgcgacc
    24061 atgattggga ttacggaggt caatcctctc tctcctcact atgtctgtgg tcagtgtcag
    24121 tacagtgagt ttatcacaga tggttcgtac ggttcaggat ttgatatgcc ccataaggac
    24181 tgtccaaact gtggtcacaa actcagtaaa aacggacagg atattccgtt tgagaccttc
    24241 cttggttttg atggggataa ggttcctgat attgacttga acttctcggg agaagatcag
    24301 cctagcgccc acttggatgt gcgtgatatc tttggtgaag aatatgcctt ccgtgcggga
    24361 acggttggta cggtagctgc caagactgcc tatggatttg tcaagggtta cgagcgagat
    24421 tatggcaagt tttatcgtga tgcagaagta gaacgcctcg ctcaaggagc ggcgggtgtc
    24481 aagcggacaa caggccaaca cccgggggga atcgttgtta ttccgaacta catggatgtc
    24541 tacgatttta cgcctgtcca gtatccagca gatgatgtca cggctgaatg gcagaccact
    24601 cactttaact tccacgatat cgatgagaac gtcctcaaac tcgatgtact gggacatgat
    24661 gatccgacca tgattcgaaa acttcaggat ttgtctggta ttgaccctaa taaaattcct
    24721 atggatgacg aaggcgtgat ggcactcttt tctgggactg atgtgctagg ggtaacacct
    24781 gaacaaattg gaacgcctac gggtatgttg gggattccag agtttggaac aaatttcgta
    24841 cgtggaatgg tagacgaaac ccatccgaca acctttgcgg aattgcttca gctgtctggt
    24901 ctgtcccacg gtactgacgt ttggttgggg aatgctcagg atctgattaa gcaaggaata
    24961 gcggacctat cgactgttat cggttgtcgg gacgacatca tggtttacct catgcatgcg
    25021 ggtctggaac ctaagatggc ctttaccatt atggaacggg tacgtaaggg tttgtggcta
    25081 aagatttcag aagaggagag aaatggctat atcgaagcca tgaaggctaa taaggtgcca
    25141 gagtggtata tcgaatcctg tgggaaaatt aagtacatgt tccctaaggc ccatgcggca
    25201 gcctacgtta tgatggcctt gcgtgtagct tacttcaagg ttcaccatcc tatttattac
    25261 tactgtgctt acttctccat tcgtgctaag gcttttgata tcaagaccat gggtgcgggc
    25321 ttggaggcca tcaagcgcag aatggaagaa atctctgaaa aacggaagaa caatgaagcc
    25381 tctaatgtgg aaatcgatct ctatacaact cttgagattg tcaatgagat gtgggaacga
    25441 ggtttcaagt ttggtaaatt agatctctac cgtagtcagg cgacagagtt cctcatcgac
    25501 ggggataccc ttatcccacc atttgtagca atggatggtc tgggagagaa cgttgccaag
    25561 caactggtgc gggcgcgtga agagggagaa ttcctctcta aaacagaact acgcaagcgt
    25621 ggtggactct catcaacctt ggttgaaaag atggatgaga tgggtattct tggaaatatg
    25681 ccagaggata accagttgag tttgtttgat gagttgtttt aaaaaattgc ttaataatct
    25741 attaaaagag gctaacgtat atccaataga tttacattag ctttcttttt tgttaaaata
    25801 gtctatggaa agagggtgag agtatgtcaa agatgagtat aagcatccgt ctggatagtg
    25861 aggttaagga gcaggcccaa caggtgttta gtaatctggg aatggatatg acaacagcta
    25921 ttaatatttt ccttcgtcag gcaattcaat atcagggatt accttttgat gttagactag
    25981 acgaaaatcg gaagttgctc caagcgttaa cggatttaga ccaaaatcgt aatatgagcc
    26041 agtcttttga atcagtctca gatttgatgg aggacttacg tgcttaagat tcgttatcat
    26101 aaacagttta aaaaagattt taagttggct atgaagcgtg gtttgaaggc agaattatta
    26161 gaagaagttt tgaattttct ggttcaagaa aaagaacatc ctgccagata tcgtgatcat
    26221 tcattgacgg catccaagca ttttcaagga gttcgtgaat gccataccca gccagattgg
    26281 cttttggttt ataaagtaga caagtcggaa ttgattttaa atttgctgag gacaggcagt
    26341 cacagtgatt tattttaatc tattttaagg gggttctcat gaaactaaga atatttgcgg
    26401 aagataagcc ggctaagaag gtatttgaat atcaattaga acttgctgat cgtacaattc
    26461 ttctatcgac agcactcttg tcaggtgcta ttgctttagc aggaatcttt tctgctttga
    26521 aagaaaaata aaaatagaaa agagaaaaca gaatggtttt accaaatttt aaagaaaatc
    26581 tagaaaaata tgcgaaattg ttggttgcga acggaattaa cgtgcaacct ggtcacactt
    26641 tggctctctc tattgatgtg gagcaacgtg aattggcaca tctaatcgtg aaagaagctt
    26701 atgccttggg tgcgcatgag gtcatcgttc agtggacaga tgatgtgatt aaccgtgaga
    26761 aattcctcca tgccccgatg gagcgtttgg acaatgtgcc agaatacaag attgctgaga
    26821 tgaactatct tttggagaac aaggctagcc gtcttggggt tcgttcatct gatccaggtg
    26881 ccttgaacgg agtggacgct gacaagcttt cagcttctgc taaagctatg ggacttgcca
    26941 tgaagccaat gcgaatcgca actcaatcta acaaggttag ctggactgta gcagccgctg
    27001 ctggacttga gtgggctaag aaagtcttcc caaatgctgc gagcgacgaa gaagcagttg
    27061 atttcctttg ggatcaaatc ttcaaaactt gtcgtgtcta cgaagcagat cctgttaagg
    27121 cttgggagga acatgcagcc attctcaaga gcaaggccga tatgcttaat aaggagcaat
    27181 tttcagccct tcactacaca gcgccaggaa cagatttaac acttggtttg ccaaagaacc
    27241 acgtttggga atcagctggt gctgtcaatg cacagggcga agaattcttg ccaaatatgc
    27301 cgacagaaga ggtcttcaca gcgcctgact tccgtcgtgc agatggttat gtcacttcta
    27361 caaaaccgct tagctacaac ggaaatatca ttgaaggcat taaggtgacc tttaaggatg
    27421 gacaaatcgt agatatcact gctgagaagg gtgatcaggt tatgaaagac cttgtctttg
    27481 aaaatgcggg tgcgcgtgcc ttgggtgaat gtgccttggt accagatcca agtccaattt
    27541 ctcagtcagg cattaccttt tttaacaccc ttttcgatga aaatgcgtca aaccacttgg
    27601 ctatcggtgc agcctatgcg actagcgttg ttgatggagc ggagatgagc gaagaggagc
    27661 ttgaagctgc agggcttaac cgttcagatg ttcacgtaga ctttatgatt ggttctaacc
    27721 aaatggatat cgatggtatt cgtgaggatg gaacgcgggt acctcttttc cgtaatggga
    27781 attgggcaaa ttaaggagat aatatgttag gaagtatgtt cgttggtctc ctagtgggat
    27841 ttttagcagg tgctatgacc aatcgtggag agcgaatggg atgttttgga aaaatgtttc
    27901 tcggttggat cggagccttt ctaggtcact tgctctttgg aacttggggg ccagttttat
    27961 caggaacagc tattatccca gcgattttag gagccatgat tgttttagct attttttgga
    28021 gacgaggaag ttaatttcct aaatctgata ctcaatgaaa atcaaagagc aaactaggaa
    28081 actagccgca ggttgctcaa agcactgctt tgaggttgca gatagaactg acgaagtcag
    28141 taacatatat acggcaaggc gacgttgacg cggtttgaag agatttttga agagtatgaa
    28201 acgaaaagga ggttggtcat tgtaccagcc tccttttgat atgatataat agttctatga
    28261 gattagataa atttttagtt gcctgtgcgg tgggaagtcg gactgaggtc aaaaacttgc
    28321 tcaaggctgg gcgcgtgact gtaaatggta aaaaagaaaa atcagctaaa ttgcagattg
    28381 atgaaaaaat agatgagatt cgctttgatg ggcaagtgtt ggagtatgaa gagtttgtct
    28441 actacatgat gaacaagccc aaaggagtta tctcagcgac tgaggatccc aagcacagaa
    28501 ccgttctgga cttgttggat gacttggcgc ggagtaagga agttttccca gtaggacgct
    28561 tggatattga cacgcatggt cttttgctct tgaccaatga tggtcagctg gctcatgttc
    28621 ttctttcgcc caagcgtcat gtggataaga cttatctggc acaagtcaag ggaatcatga
    28681 cccaagaaga tgtggagaca tttgctgagg gtattcctct caaagacttt acctgtcaac
    28741 ccgctatact ggagcttgta tccatagata cagaaaagaa tcagagccaa atccgtgtga
    28801 ccattgcaga agggaagttt catcagatca agcgtatggt gggctactgt ggcaaggaag
    28861 tggtggactt gcaacgattg actatgggaa ctttagtatt agatgagaac ctggaacgag
    28921 gggaatggcg tcgcttgacc aaggaagaat tagaaattct ccgcgctaat attatttaat
    28981 ttagt
//
LOCUS       DAVLXH010000022        27994 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00028199
            SAMN33607166-rid17955573.denovo.022, whole genome shotgun sequence.
ACCESSION   DAVLXH010000022 DAVLXH010000000
VERSION     DAVLXH010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607166
            Sequence Read Archive: SRR23725544
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 27994)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27994)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721421.1
            Genome Coverage       :: 115x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:42:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,210
            CDSs (total)                      :: 2,161
            Genes (coding)                    :: 2,023
            CDSs (with protein)               :: 2,023
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 73 of 138
            Pseudo Genes (incomplete)         :: 60 of 138
            Pseudo Genes (internal stop)      :: 40 of 138
            Pseudo Genes (multiple problems)  :: 31 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27994
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607166-rid17955573.denovo.022"
                     /strain="AUSMDU00028199"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1349"
     gene            <1..1068
                     /locus_tag="VYO11_001092"
     CDS             <1..1068
                     /locus_tag="VYO11_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000636508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-glycerol glycerophosphotransferase family
                     protein"
                     /protein_id="HEV1595677.1"
                     /translation="LKNNKILFINFNGKGYGDNPKSICEYLRTTYPELDLVWLTKETK
                     GFPDGVRLVKYGSIRAFYEQASSKVWVYNVRAFARILKRKEQFYIQTWHGASSFKLIE
                     KQAELPLNYVLEAKYDARVTDLMISDSKKQTEEYRKYFWYTGEILEVGMPRNDSLFHC
                     KDDYNKLENVRKELNISCDDFVILYAPTFRDNGDISYLNLDFLRLLQSVEKGIRKNCK
                     LLIRLHPNHSQFCRNILFNQDIINVTFFSDMQELILLADVLLTDYSSSIFDFILLNKP
                     YVRYVNDLEEYSKLRGLSDTYYELPDTIISTSEELYTLLPEKINDFDYAAINQYRNGT
                     LSPMFNGRASENIGRRIIQEL"
     gene            1104..2132
                     /locus_tag="VYO11_001093"
     CDS             1104..2132
                     /locus_tag="VYO11_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000794266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HEV1595678.1"
                     /translation="MKNNVLKIGSGAIHQISSTLAQNNISGKILYCADPIVDNLYGSL
                     VRSQIEEIGRLKEESCNYNTIAYAMNIAERVIATDIDCIVGMGGGRVLDVCKYASYIS
                     KRPYLSIPTTAANDGIASPVAVLKRQDDRPKSLGAAIPSMTLIDIDVIASGPIQNIKA
                     GIGDTISNYTALKDWELAVNRGKDEMHGFAYLMSQNSLDALMKTKYNSITPDFIEVLI
                     NSLVLSGIAMDFAGSSRPVSGSEHLFSHALDYYGSKRNLHGIQVALGTVAVLKIIEDP
                     ITPVTDYLQRFEVNINPKQMGIDEDLFVYCMQHATTMRNNRYTYLHEADLSTARVKQI
                     YKELVNEL"
     gene            2148..2852
                     /locus_tag="VYO11_001094"
     CDS             2148..2852
                     /locus_tag="VYO11_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000645462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocholine cytidylyltransferase family
                     protein"
                     /protein_id="HEV1595679.1"
                     /translation="MKALILAAGLGTRLAPITNDVPKSLVPVNGKPILIKQIENLYQN
                     DVTDITIISGYKASVLKDVISGKYPEIKIIDNVDYKITNNMYSAYLGKDAMGSSEFLM
                     MNADVFYDASVIKSLLLHEAPNAIVTDLGTYIDESMKVVEKNGRLVEISKQISPEEAL
                     GASIDVYKFSPDAGACFFEKCREFIEDKNELQLWSEVALNAILQAVEFVACPLDGRWL
                     EIDNHEDLAAAEKLFA"
     gene            2873..3700
                     /locus_tag="VYO11_001095"
     CDS             2873..3700
                     /locus_tag="VYO11_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IIA family hydrolase"
                     /protein_id="HEV1595680.1"
                     /translation="MINKVDYFGMDISDLKNKKLFLFDMDGTIYEEDRLFDGTLQLLE
                     YIQSIGGEYIFITNNSSKSVVDYIEKVNQLGIVAKRENFFTSAQATIVFIEEKYPHAK
                     VYCQGTKSLLKELSDSGIDVTDQVRDNIDLVLVGFDTELTSEKIRNTCEVLSTRDVPF
                     IATNPDVRCPVSFGFLPDCGSICEMISKSVDKTPIYIGKPEPTMVNIVRKKLNYSLSE
                     TVVIGDRLYTDIMTGINAGVSSVCVLTGEATADDIQQGSIKPTYTFRTVKEMWEGII"
     gene            3841..4710
                     /gene="rfbA"
                     /locus_tag="VYO11_001096"
     CDS             3841..4710
                     /gene="rfbA"
                     /locus_tag="VYO11_001096"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002276675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HEV1595681.1"
                     /translation="MKGIILAGGSGTRLYPLTRAASKQLMPVYDKPMIYYPLSTLMLA
                     GIKDILIISTPQDLPRFKDLLLDGSEFGIKLSYAEQPSPDGLAQAFLIGEEFIGDDSV
                     ALILGDNIYHGPGLSKMLQKAAQKEKGATVFGYQVKDPERFGVVEFDTDMNAISIEEK
                     PENPRSNYAVTGLYFYDNDVVEIAKGIKPSARGELEITDINKVYLNRGDLSVELMGRG
                     FAWLDTGTHESLLEASQYIETVQRMQNVQVANLEEIAYRMGYISREDVLELAQPLKKN
                     EYGQYLLRLIGEA"
     gene            4711..5304
                     /locus_tag="VYO11_001097"
     CDS             4711..5304
                     /locus_tag="VYO11_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase family
                     protein"
                     /protein_id="HEV1595682.1"
                     /translation="MSDNFFGKTLAVRKVDAIPGLLEFDIPVHGDNRGWFKENFQKEK
                     MLPLGFPESFFVAGKLQNNVSFSRKNVLRGLHAEPWDKYISVADDGKVLGSWVDLREG
                     ETFGNVYQTEIDASKGIFVPRGVANGFQVLSDTVSYSYLVNDYWALELKPKYAFVNYA
                     DPSLGIEWENLAEAEVSEADKHHPLLRDVKPLTKDEL"
     gene            5316..6362
                     /gene="rfbB"
                     /locus_tag="VYO11_001098"
     CDS             5316..6362
                     /gene="rfbB"
                     /locus_tag="VYO11_001098"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HEV1595683.1"
                     /translation="MTEYKKIIVTGGAGFIGSNFVHYVYNNFPDVHVTVLDKLTYAGN
                     RANIEEILGDRVELVVGDIADAALVDKLAAEADAIVHYAAESHNDNSLNDPSPFIHTN
                     FIGTYTLLEAARKYDIRFHHVSTDEVYGDLPLREDLPGHGEGLGEKFTAETKYNPSSP
                     YSSTKAASDLIVKAWVRSFGVKATISNCSNNYGPYQHIEKFIPRQITNILSGIKPKLY
                     GEGKNVRDWIHTNDHSSGVWTILTKGQIGETYLIGADGEKNNKEVLELILKEMGQPAD
                     AYDHVTDRAGHDLRYAIDASKLRDELGWKPEFTNFEAGLKETIKWYTDNQDWWKSEKE
                     AVEANYAKTQQVIK"
     gene            complement(6424..7278)
                     /gene="rfbD"
                     /locus_tag="VYO11_001099"
     CDS             complement(6424..7278)
                     /gene="rfbD"
                     /locus_tag="VYO11_001099"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HEV1595684.1"
                     /translation="MILITGANGQLGTELRYLLDERNVDYVAVDVTEMDITNSEMVEK
                     VFAEVKPTLVYHCAAYTAVDAAEDEGKELDFAINVTGTENVAKASEKYGAILVYISTD
                     YVFDGKKPVGQEWEVDDIPDPQTEYGRTKRMGEELVENLTSQHYIIRTAWVFGNYGKN
                     FVFTMQSLAKTHKTLTVVNDQYGRPTWTRTLAEFMTYVTENQKEYGYYHLSNDAAEDT
                     TWYDFASEILKDSDVEVVPVDSSKFPAKAKRPLNSTMSLAKAKATGFVIPTWQDALKE
                     FYKQEVRK"
     gene            7524..9506
                     /locus_tag="VYO11_001100"
     CDS             7524..9506
                     /locus_tag="VYO11_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV1595685.1"
                     /translation="MKSSRLLALAGVTLLAATTLAACSGSGSSTKGEKTFSYIYETDP
                     DNLNYLTTAKAATANITSNVVDGLLENDRYGNFVPSMAEDWSVSKDGLTYTYTIRKDA
                     KWYTSEGEEYAAVKAQDFVTGLKYAADKKSDALYLVQESIKGLDAYVKGEIKDFSQVG
                     IKALDEQTVQYTLNKPESFWNSKTTMGVLAPVNEEFLNSKGDDFAKATDPSSLLYNGP
                     YLLKSIVTKSSVEFAKNPNYWDKDNVHVDKVKLSFWDGQDTSKPAENFKDGSLTAARL
                     YPTSASFAELEKSMKDNIVYTQQDSITYLVGTNIDRQSYKYTSKTSDEQKASTKKALL
                     NKDFRQAIAFGFDRTAYASQLNGQTGASKILRNIFVPPTFVQADGKNFGDMVKEKLVT
                     YGDEWKDVNLADSQDGLYNPEKAKAEFAKAKSALQAEGVTFPIHLDMPVDQTATTKVQ
                     RVQSMKQSLEATLGADNVIIDIQQLQKDEVNNITYFAENAAGEDWDLSDNVGWGPDFA
                     DPSTYLDIIKPSVGESTKTYLGFDSGEDNVAAKKVGLYDYEKLVTEAGDEATDVAKRY
                     DKYAAAQAWLTDSALIIPTTSRTGRPILSKMVPFTIPFALSGNKGASEPILYKYLELQ
                     DKAITVDEYQKAQEKWMKEKEESNKKAQEDLAKHVK"
     gene            9806..15109
                     /locus_tag="VYO11_001101"
     CDS             9806..15109
                     /locus_tag="VYO11_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001032503.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HEV1595686.1"
                     /translation="MNKGLFEKRCKYSIRKFSLGVASVMIGAAFFGTSPVLADSVQSG
                     STANLPTDLATALATAKENDGRDFEAPKVGEDQGSPEVTDGPKTEEELLALEKEKPAE
                     EKPKEDKPAAAKPETPKTVTPEWQTVEKKEQQGTVTIREEKGVRYNQLSSTAQNDNAG
                     KPALFEKKGLTVDANGNATVDLTFKEDSEKGKSRFGVFLKFKDTNNNVFVGYDKDGWF
                     WEYKSPTTSTWYRGSRVAAPETGSTNRLSITLKSDGQLNASNNDVNLFDTVTLPAAVN
                     DHLKNEKKILLKAGSYDDERTVVSVKTDNQEGVKTEDTPAEKETGPVVDDSKVTYDTI
                     QSKVLKAVIDQAFPRVKEYSLNGHTLPGQVQQFNQVFINNHRITPEVTYKKINETTAE
                     YLMKLRDDAHLINAEMTVRLQVVDNQLHFDVTKIVNHNQVTPGQKIDDERKLLSSISF
                     LGNALVSVSSDQTGAKFDGATMSNNTHVSGDDHIDVTNPMKDLAKGYMYGFVSTDKLA
                     AGVWSNSQNSYGGGSNDWTRLTAYKETVGNANYVGIHSSEWQWEKAYKGIVFPEYTKE
                     LPRAKVVITEDANADKKVDWQDGAIAYRSIMNNPQGWEKVKDITAYRIAMNFGSQAQN
                     PFLMTLDGIKKINLHTDGLGQGVLLKGYGSEGHDSGHLNYADIGKRIGGVEDFKTLIE
                     KAKKYGAHLGIHVNASETYPESKYFNEKILRKNPDGSYSYGWNWLDQGINIDAAYDLA
                     HGRLARWEDLKKKLGDGLDFIYVDVWGNGQSGDNGAWATHVLAKEINKQGWRFAIEWG
                     HGGEYDSTFHHWAADLTYGGYTNKGINSAITRFIRNHQKDAWVGDYRSYGGAANYPLL
                     GGYSMKDFEGWQGRSDYNGYVTNLFAHDVMTKYFQHFTVSKWENGTPVTMTDNGSTYK
                     WTPEMRVELVDADNNKVVVTRKSNDVNSPQYRERTVTLNGRVIQDGSAYLTPWNWDAN
                     GKKLSTDKEKMYYFNTQAGATTWTLPSDWAKSKVYLYKLTDQGKTEEQELTVKDGKIT
                     LDLLANQPYVLYRSKQTNPEMSWSEGMHIYDQGFNSGTLKHWTISGDASKAEIVKSQG
                     ANDMLRIQGNKEKVSLTQKLTGLKPNTKYAVYVGVDNRSNAKASITVNTGEKEVTTYT
                     NKSLALNYVKAYAHNTRRDNATVDDTSYFQNMYAFFTTGSDVSNVTLTLSREAGDQAT
                     YFDEIRTFENNSSMYGDKHDTGKGTFKQDFENVAQGIFPFVVGGVEGVEDNRTHLSEK
                     HNPYTQRGWNGKKVDDVIEGNWSLKTNGLVSRRNLVYQTIPQNFRFEAGKTYRVTFEY
                     EAGSDNTYAFVVGKGEFQSGRRGTQASNLEMHELPNTWTDSKKAKKATFLVTGAETGD
                     TWVGIYSTGNASNTRGDSGGNANFRGYNDFMMDNLQIEEITLTGKMLTENALKNYLPT
                     VAMTNYTKESMDALKEAVFNLSQADDDISVEEARAEIAKIEALKNALVQKKTALVADD
                     FASLTAPAQAQEGLANAFDGNVSSLWHTSWNGGDVGKPATMVLKEPTEITGLRYVPRG
                     SGSNGNLRDVKLVVTDESGKEHTFTATDWPDNNKPKDIDFGKTIKAKKIVLTGTKTYG
                     DGGDKYQSAAELIFTRPQVAETPLDLSGYEAALVKAQKLTDKDNQEEVASVQASMKYA
                     TDNHLLTERMVEYFADYLNQLKDSATKPDAPTVEKPEFKLRSLASEQGKTPDYKQEIA
                     RPETPEQILPATGESQSDTALILASVSLALSALFVVKTKKD"
     gene            complement(15276..17435)
                     /locus_tag="VYO11_001102"
     CDS             complement(15276..17435)
                     /locus_tag="VYO11_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001040003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HEV1595687.1"
                     /translation="MNKPTILRLIKYLSISFLSLVIAAIVLGGGVFFYYVSKAPSLSE
                     SKLVATTSSKIYDNKNQLIADLGSERRVNAQANDIPTDLVKAIVSIEDHRFFDHRGID
                     TIRILGAFLRNLQSNSLQGGSTLTQQLIKLTYFSTSTSDQTISRKAQEAWLAIQLEQK
                     ATKQEILTYYINKVYMSNGNYGMQTAAQNYYGKDLNNLSLPQLALLAGMPQAPNQYDP
                     YSHPEAAQDRRNLVLSEMKNQGYISAEQYEKAVNTPITDGLQSLKSASNYPAYMDNYL
                     KEVINQVEEETGYNLLTTGMDVYTNVDQEAQKHLWDIYNTDEYVAYPDDDLQVASTVV
                     DVSNGKVIAQLGARHQASNVSFGTNQAVETNRDWGSTMKPITDYAPAIEYGVYDSTAT
                     MVNDIPYNYPGTSTPVYNWDRAYFGNITLQYALQQSRNVTAVETLNKVGLDRAKTFLN
                     GLGIDYPSIHYANAISSNTTESNKHYGASSEKMAAAYAAFANGGIYHKPMYINKIVFS
                     DGSEKEFSDAGTRAMKETTAYMMTEMMKTVLAYGTGRGAYLPWLPQAGKTGTSNYTDD
                     EIEKHIKNTGYVAPDEMFVGYTRKYSMAVWTGYSNRLTPIVGDGFLVAAKVYRSMISY
                     LSEDDQPGDWTMPDGLFRNGEFVFKNGARSTWNSPAPQQPPSTESSSSSSDSSTSQSS
                     STTPSTNNSTTTNPNNNTQQSNTTPDQQNQNPQPAQP"
     gene            complement(17432..18028)
                     /gene="recU"
                     /locus_tag="VYO11_001103"
     CDS             complement(17432..18028)
                     /gene="recU"
                     /locus_tag="VYO11_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HEV1595688.1"
                     /translation="MVNYPHKVSSQKRQKSLSQPKNFANRGMSFEKMINATNDYYLSQ
                     GLAVIHKKPTPIQIVQVDYPQRSRAKIVEAYFRQASTTDYSGVYNGYYIDFEVKETKQ
                     KRAIPMKNFHPHQIQHMEQVLAQQGICFVLLHFSSQQETYLLPAFDLIRFYHQDKGQK
                     SMPLEYIREYGYEIKAGAFPQIPYLNVIKEHLLGGKTR"
     gene            18094..18621
                     /locus_tag="VYO11_001104"
     CDS             18094..18621
                     /locus_tag="VYO11_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HEV1595689.1"
                     /translation="MATALVLGYSAFDLGLFSDKDPRLKLIKKAIRKDLEAMAADGVS
                     WLVFTGSLGFEYWVLEVAQEMKTEYGFQLATIFAFETHGENWNEGNQMKLSRFKQVDF
                     VKYAYPRYEHKGQLRDYQQFLLENTTSSYLFYDEENEIKLAYFYQKMKNQEDYFIKRL
                     TFDQLNELAENFSEN"
     gene            18691..19020
                     /gene="gpsB"
                     /locus_tag="VYO11_001105"
     CDS             18691..19020
                     /gene="gpsB"
                     /locus_tag="VYO11_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000146522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HEV1595690.1"
                     /translation="MASIIFSAKDIFEQEFGREVRGYNKVEVDEFLDDVIKDYETYAA
                     LVKSLRQEIADLKEELTRKPKPSPVQAEPLEAAITSSMTNFDILKRLNRLEKEVFGKQ
                     ILDNSDF"
     gene            19041..19421
                     /gene="rnpB"
                     /locus_tag="VYO11_001106"
     ncRNA           19041..19421
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="VYO11_001106"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            19506..20663
                     /locus_tag="VYO11_001107"
     CDS             19506..20663
                     /locus_tag="VYO11_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HEV1595691.1"
                     /translation="MKKEFNLIATVAAGLEAVVGREVRELGYDCQVENGRVRFQGDVR
                     AIIETNLWLRAADRIKIIVGTFPAKTFEELFQGVFALDWENYLPLGARFPISKAKCVK
                     SKLHNEPSVQAISKKAVVKKLQKHYARPEGVPLMENGPEFKIEVSILKDVATVMIDTT
                     GSSLFKRGYRTEKGGAPIKENMAAAILQLSNWYPDKPLIDPTCGSGTFCIEAVMIARK
                     MAPGLRRSFAFEEWNWISDRLIQEVRTEAAKKVDRELELDIMGCDIDARMVEIAKANA
                     QAAGVAGDITFKQMRVQDLRSDKINGVIISNPPYGERLSDDAGVTKLYAEMGQVFAPL
                     KTWSKFILTSDEAFESKYGSQADKKRKLYNGTLKVDLYQYFGQRVKRQEVK"
     gene            20676..22046
                     /gene="mapZ"
                     /locus_tag="VYO11_001108"
     CDS             20676..22046
                     /gene="mapZ"
                     /locus_tag="VYO11_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mid-cell-anchored protein MapZ"
                     /protein_id="HEV1595692.1"
                     /translation="MSKKRRNRHKKEGQEPQFDFDEAKELTVGQAIRKNEEVEAGVLP
                     EDSILDKYVKQHRDEIEADKFATRQYKKEEFVETQSLDDLIQEMREAVEKSEASSEEV
                     PSSEDILLPLPLDDEEQGLDPLLLDDENPTEMTEEVEEEQNLSRLDQEDSEKKSKKGF
                     ILTVLALVSVIICVSAYYVYRQVARSTKEIETSQSITANQSDVDDFNTLYDAFYTDSN
                     KTALKNSQFDKLNQLKTLLDKLEGSREHTLAKSKYDSLATQIKAIQDVNAQFEKPAIV
                     DGVLDTNAKAKLDAKFTDIKTGNTELDKVLDKAISLGKSQQTSTSSSSSSQASSNTTS
                     ELKPSSSNETRSSRSEVNMGLSSAGVAVQRSASRVAYNQSAIDDSNNSAWDFADGVLE
                     QILATSRSRGYITGDQYILERVNIVNGNGYYNLYKPDGTYLFTLNCKTGYFVGNGAGH
                     ADDLDY"
     gene            22122..23546
                     /gene="gndA"
                     /locus_tag="VYO11_001109"
     CDS             22122..23546
                     /gene="gndA"
                     /locus_tag="VYO11_001109"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HEV1595693.1"
                     /translation="MTKANFGVVGMAVMGRNLALNIESRGYTVAIYNRSKEKTEDVIA
                     CHPEKNFVPSYDVESFVNSIEKPRRIMLMVQAGPGTDATIQALLPHLDKGDILIDGGN
                     TFYKDTIRRNEELANSGINFIGTGVSGGEKGALEGPSIMPGGQKEAYELVADVLEEIS
                     AKAPEDGKPCVTYIGPDGAGHYVKMVHNGIEYGDMQLIAESYDLMQHLLGLSAEDMAE
                     IFTEWNKGELDSYLIEITADILSRKDDEDQDGPIVDYILDAAGNKGTGKWTSQSSLDL
                     GVPLSLITESVFARYISTYKEERVHASKVLPKPAAFNFEGDKAELIEKIRQALYFSKI
                     ISYAQGFAQLRVASKENNWNLPFADIASIWRDGCIIRSRFLQKITDAYNRDADLANLL
                     LDEYFLDVTAKYQQAVRDIVALAVQAGVPVPTFSAAITYFDSYRSADLPANLIQAQRD
                     YFGAHTYQRKDKEGTFHYSWYDEK"
     gene            23558..24247
                     /locus_tag="VYO11_001110"
     CDS             23558..24247
                     /locus_tag="VYO11_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000518023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1595694.1"
                     /translation="MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQ
                     TDYDLILLNVNLGDMMAQDFAEKLSRTKPASVIMILDHWEDLQEELEVVQRFAVSYIY
                     KPVFIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
                     REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIK
                     TVRGVGYTMQE"
     gene            24345..25364
                     /gene="cbpC"
                     /locus_tag="VYO11_001111"
     CDS             24345..25364
                     /gene="cbpC"
                     /locus_tag="VYO11_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpC"
                     /protein_id="HEV1595695.1"
                     /translation="MKLLKKMMQVLLAVFFFGLLATNTVFANTTGGRFVDKDNRKYYV
                     KDDHKAIYWHKIDGKTYYFGDIGEMVVGWQYLEIPGTGYRDDLFDNRPVFEIGLQEKW
                     YYFGQDGALLEQTDKQVLEAKTSENTGKVYGEQYPLSAEKRTYYFDNNYAVKTGWIYE
                     DGNWYYLNKLGNFGDDSYNPLPIGEVAKGWTQDFHVTIDIDRSKPAPWYYLDPTTGIM
                     QTGWQYLGNKWYYLRSSGAMATGWYQAGTTWYYLDQPNGDMKTGWQNLGNKWYYLRSS
                     GAMATGWYQDGSTWYYLNAGNGDMKTGWFQVNGNWYYAYSSGALAVNTTVDGYSVNYN
                     GEWVR"
     gene            complement(25482..26714)
                     /locus_tag="VYO11_001112"
     CDS             complement(25482..26714)
                     /locus_tag="VYO11_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEV1595696.1"
                     /translation="MKLFWTNNIYRQLLLNSCFSSFGDSIFYLAIINYVAQYNFAPLA
                     ILLISISEMVPLLSQLFLGILGDFQENRVKHALCIAKIKILLYAILTVFLVLSPFSLV
                     SVIMIVIINLISDTLSYLSAYMMNALYISVIKDDLHDAMGFRQSLMRVVRIVANLAGA
                     FLINVISIQTISLINTLTFVIAFLGLYVIRHTLYEVEKRIEMSHTALSFKKYFQHLKQ
                     SLAVLLKLKDTVILLFLTTSMIAILDVSPRLIALRFIQQTLAQLSIGQLLALLSIIMS
                     CGAILGNMTSSNLFKNIRFTHLLVFCEISLLALITSILCQAYIVIFVTSFISSTIIGI
                     LSPRLQAAVFAHIPSDKMGTVGSALSTVDILAPSLLSLLALSIASGVSVQLALIFLYL
                     ILIALIFCQWLVKFNTHN"
     gene            complement(27244..27719)
                     /locus_tag="VYO11_001113"
                     /pseudo
     CDS             complement(27244..27719)
                     /locus_tag="VYO11_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811282.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic-modifying protein"
BASE COUNT         8743 a         4944 c         6177 g         8130 t
ORIGIN      
        1 ttaaaaaata ataagattct atttattaat ttcaatggga agggttatgg tgataatcct
       61 aaaagtattt gcgagtacct aagaactaca tatccagaat tagatttagt atggctcact
      121 aaagaaacaa aagggtttcc agatggagtc agactagtaa aatatggttc aattcgagct
      181 ttttacgaac aagctagttc aaaagtatgg gtgtataatg tgagggcgtt tgctaggata
      241 ctaaaaagaa aagagcaatt ttatattcag acttggcatg gtgcttcaag ttttaaactg
      301 atagaaaaac aggctgaatt acctttgaac tatgttctgg aagctaaata tgatgcacga
      361 gtgacggatt taatgatttc agacagtaag aagcaaactg aggaatacag aaaatatttt
      421 tggtatactg gtgaaattct tgaggtaggg atgccaagaa atgattcctt gtttcattgt
      481 aaagacgatt ataataagtt agaaaatgtt cgaaaagaac ttaatatctc ctgtgatgat
      541 tttgtcattt tatatgcacc aacttttaga gataatggtg atatatccta tttgaattta
      601 gattttctac gcctgttaca gagtgtggaa aaaggaatta gaaagaattg taaattatta
      661 attaggttgc atcctaacca ctcacaattt tgtagaaata ttttatttaa tcaggatata
      721 attaatgtta cattcttttc agatatgcag gaactcatat tgttggcaga tgttctacta
      781 acagattatt cttcatctat atttgatttt atactcttaa ataagccgta tgtaagatat
      841 gtgaatgatc ttgaggaata ttctaaactt agaggattat cggatacata ttatgagcta
      901 cctgacacta tcatttcgac atcggaggaa ctgtataccc tcctgcctga aaaaataaat
      961 gattttgatt atgctgctat aaatcaatat agaaatggaa cccttagtcc aatgtttaat
     1021 ggaagagcta gtgaaaatat aggaaggaga ataattcaag aattgtaaag aaaatcattg
     1081 aattattttt taggtgaaaa ggtttgaaaa ataatgtatt aaaaataggc agtggggcta
     1141 ttcatcaaat atcctctaca cttgctcaaa ataatatatc aggtaagatt ctatattgtg
     1201 ctgatccaat tgttgacaat ctatatggct ctttagttag gtcacaaatt gaggagatag
     1261 gtcgattaaa agaagaaagt tgtaattata atacgattgc ttacgcaatg aatatagccg
     1321 agcgagttat tgcaacagat attgattgta ttgtgggaat gggaggtggt cgcgttttag
     1381 atgtttgtaa atatgcatct tatatttcaa aacggccata tttatcaatt cccaccactg
     1441 cagcgaatga tgggatagct tctccagtag cagttttgaa aagacaagat gatagaccta
     1501 aaagtttggg tgcggcaatt ccatctatga ctcttatcga tattgatgtt attgcatcag
     1561 gacccataca gaatattaaa gcgggcattg gtgatacgat ttcaaattat acggcgttga
     1621 aagattggga attagctgtt aaccgaggca aggatgaaat gcatggcttt gcctatttaa
     1681 tgtcccaaaa ctccttggac gctttgatga aaacaaagta taattctatt acgcctgatt
     1741 tcattgaagt tttgataaat tcattagttt tatcaggtat tgcaatggat tttgcaggaa
     1801 gtagtagacc agttagtggt tcagaacact tatttagtca tgccttggat tattatggtt
     1861 ccaagagaaa ccttcatggt attcaggttg cattaggtac agttgcagta ttaaaaataa
     1921 ttgaagatcc gattacacca gtgacggatt acttgcaaag atttgaggta aatatcaatc
     1981 caaaacaaat gggaatcgat gaagacctat ttgtttattg tatgcaacat gctacaacaa
     2041 tgagaaataa tcgctataca tatcttcatg aagctgattt aagcacagct agggtgaaac
     2101 aaatatataa agaattagta aatgagttgt agaaaagaga ggaaaaaatg aaagcactta
     2161 ttttagcagc aggtttagga acacgtttgg ctcctatcac taatgacgtc ccaaaatcat
     2221 tagttcctgt taatggaaaa cctattctta taaaacaaat tgaaaattta tatcaaaatg
     2281 atgtaacaga tatcacaatt atttctggct ataaggcatc agtattaaag gatgtaattt
     2341 ccgggaaata ccctgaaatt aagattattg ataatgttga ttataaaata acaaataata
     2401 tgtactcagc ctatctaggt aaagatgcaa tggggagtag tgaattctta atgatgaatg
     2461 cagatgtgtt ttatgatgct tccgtcatta aaagtttgtt acttcatgaa gctccgaacg
     2521 caattgtaac tgatttagga acctacattg atgaatctat gaaagtcgta gaaaagaatg
     2581 gtcgtttagt agaaatttct aaacagattt cacctgagga ggctttagga gcttctattg
     2641 atgtttataa attttctcct gatgcaggag cttgtttctt tgaaaaatgt agagagttca
     2701 ttgaagataa aaatgagctt caactgtgga gcgaggtcgc acttaatgcg attctccaag
     2761 ctgttgaatt cgtagcttgt ccgctggatg ggcgttggtt ggaaattgac aatcatgaag
     2821 atcttgctgc agctgaaaaa ctatttgctt aaaacaaata gggaggacag atttgataaa
     2881 taaagttgat tattttggga tggatatcag tgacttaaag aataaaaaat tatttttatt
     2941 tgatatggat ggtaccattt atgaagaaga tagattgttt gatgggacac ttcagttatt
     3001 agaatatatt caaagtattg gtggtgagta tatttttatt acgaacaatt cctcaaagtc
     3061 agttgttgac tatattgaaa aagttaacca attaggtatt gtggctaaac gggagaattt
     3121 ttttacttct gctcaagcaa cgattgtttt tatcgaggaa aaatatcctc acgcaaaggt
     3181 gtattgtcag ggaacgaaat cattgttaaa agaactatcc gattcgggaa tcgatgttac
     3241 cgatcaagtg agagataaca tagatcttgt tttagttggt tttgatacag aactaacaag
     3301 tgagaaaatc cgtaatacct gtgaagtttt gtcaacgaga gatgtcccat tcattgccac
     3361 gaatccagat gttcgttgcc cagtttcctt tggttttctt ccagattgtg gttcgatttg
     3421 cgaaatgatt agcaaatcag ttgataaaac tcctatttat attggtaaac ctgaaccgac
     3481 gatggttaac atagttagaa aaaaattgaa ttactctttg tcagaaacgg ttgtaatcgg
     3541 tgatcgttta tacaccgata tcatgacagg tattaatgca ggagtatcct cagtatgtgt
     3601 attaacagga gaagcaacag ctgatgatat tcaacaaggg agtataaagc ctacttatac
     3661 ttttagaact gtgaaagaga tgtgggaagg aattatatga ttctctaggt tattgattta
     3721 taaacttagg gatatgacct tgaaatgtta atagcaattt agtatggaca attaaaattt
     3781 actttcctcc tagtggtttg tcaaagtaaa agacttatca aaaaagaaag gtacactatt
     3841 atgaaaggta ttattcttgc aggcggctca ggtacccgcc tgtacccact tactcgggct
     3901 gcgtcaaaac agctgatgcc ggtttatgat aaacctatga tttattatcc gttgtcgaca
     3961 ttaatgttgg ctggaattaa agatattttg attatctcaa ctcctcaaga tttgccccgg
     4021 tttaaggact tgctcttgga tggttccgaa tttgggatca agctttctta tgcggaacaa
     4081 cctagtccag atggacttgc tcaggctttt cttatcggtg aagaatttat cggtgacgat
     4141 agtgttgcct tgattttggg cgacaatatc tatcatggac ctggtttgag caaaatgctt
     4201 caaaaggcag cccagaaaga gaaaggtgca actgtttttg gctaccaagt gaaggatcca
     4261 gagcgttttg gtgtggtcga gtttgataca gatatgaatg ccatttccat agaagaaaaa
     4321 ccagagaatc ctcgatccaa ctatgccgtg accggtctgt atttctatga taatgatgtt
     4381 gtagaaattg ctaaaggtat taaaccaagt gcacgtggcg agttagaaat tacagatatc
     4441 aacaaggttt acctaaatcg tggtgacctt tctgttgagc tgatggggcg tggttttgcc
     4501 tggttggata cgggaaccca tgaaagcctg ctagaagctt ctcagtatat tgaaacggtt
     4561 cagcgtatgc agaatgttca agttgcaaac ttggaagaaa ttgcctatcg catgggctat
     4621 atcagtcgtg aagatgtgct cgagttggcg caacctctga agaagaatga atacggacaa
     4681 tatttgctcc gtttgattgg agaagcatag atgtcagata atttttttgg aaagacactt
     4741 gcggtacgca aggttgatgc tataccagga ctgctagagt ttgacattcc cgttcatgga
     4801 gacaatcgtg gttggtttaa ggaaaacttc cagaaggaaa agatgctacc gcttggtttt
     4861 cctgaaagct tctttgttgc agggaaattg caaaacaacg tcagcttttc tcgaaaaaat
     4921 gttcttcgag gattgcatgc agaaccttgg gacaagtata tctctgttgc agacgatggg
     4981 aaggttttag gatcttgggt ggatttgcgt gaaggcgaga cttttggaaa tgtttaccag
     5041 acagagattg atgctagcaa gggaattttt gtccctcgtg gcgtcgccaa tggtttccaa
     5101 gtcctctcgg atacagtttc ctatagctat ctggtcaatg actactgggc tcttgaacta
     5161 aaacccaaat atgcctttgt caactatgct gacccatcct tgggaattga gtgggaaaat
     5221 ctagcggaag ctgaggtttc agaggcagac aaacaccatc ctctattaag ggatgtcaaa
     5281 ccacttacga aagacgagtt gtaaaaggaa acattatgac tgaatacaaa aaaattatcg
     5341 tgacaggtgg agctggtttt atcggttcta actttgtcca ctatgtttac aataactttc
     5401 cagatgtcca tgtgacagtg ctggacaagc tgacttatgc aggtaatcgt gccaatatcg
     5461 aggaaatttt aggcgaccgt gttgagttgg ttgttggaga tattgctgat gcagccttgg
     5521 tagacaagtt ggcggctgaa gcggatgcta tcgttcacta tgcggcagaa agccacaatg
     5581 ataactcgct caatgacccg agtccattta tccacaccaa ctttatcgga acttacacac
     5641 ttttagaagc ggctcgtaaa tacgacattc gtttccacca tgtatcgact gatgaagtct
     5701 atggtgacct gcctctgcgt gaagatttgc caggtcatgg ggaaggccta ggtgagaaat
     5761 ttaccgctga aaccaagtac aatccaagct cgccttactc atcaaccaag gctgcttcag
     5821 acttgatcgt taaagcttgg gtgcgctcat ttggtgttaa agcaacgatt tctaactgtt
     5881 caaacaacta tggtccatac cagcatatcg agaagttcat tccgcgccag attacgaata
     5941 tcttgagcgg tatcaagcca aaactctacg gagaaggtaa gaatgtgcgt gactggattc
     6001 acaccaatga ccattcatca ggcgtttgga cgattctgac caagggtcaa atcggtgaaa
     6061 cttacttgat cggtgctgac ggtgagaaga acaacaagga agtgttagag ctcattctca
     6121 aggagatggg gcaacccgct gacgcttatg accatgtgac cgatcgagct ggtcacgact
     6181 tgcgttatgc gattgatgct agcaagctcc gtgatgagtt ggggtggaag ccagagttta
     6241 ccaactttga agcaggcctc aaagagacca tcaagtggta cacagataac caagactggt
     6301 ggaaatctga aaaagaagca gtagaggcta actatgctaa aacgcaacaa gtgattaaat
     6361 aataagatac taaaaaagca agagacctcg aggtctcttg cttttctagt atgtagtaag
     6421 cttttatttt cttacttctt gtttataaaa ctctttaagg gcatcttgcc aggttgggat
     6481 gacgaaacct gttgcctttg cctttgccaa actcatagtt gagttgagag gtcgtttagc
     6541 cttagcgggg aacttgctag agtctactgg cactacttca acatcactgt ccttaagaat
     6601 ctcgctagca aagtcatacc aagtggtgtc ttcagctgcg tcatttgata agtgatagta
     6661 gccatactct ttttgatttt cagtcacata ggtcatgaat tcggccaagg tccgtgtcca
     6721 agttgggcga ccgtattggt cgttgaccac tgtgagcgtt ttatgggttt tggctaggct
     6781 ttgcatggta aagacaaagt tttttccata atttccaaaa acccaagcag tacgaatgat
     6841 gtaatgctgt gacgtaaggt tttcaacaag ttcttctccc attcgcttgg tacgtccgta
     6901 ctctgtttgc ggatcaggta tgtcatcgac ttcccactct tgtcctactg gtttctttcc
     6961 atcaaagacg tagtctgttg agatatagac cagaatagct ccgtatttct cagaggcctt
     7021 ggctacattt tcagttccag ttacgttgat ggcaaaatcc agttctttcc cttcatcttc
     7081 ggctgcatca acagcagtgt aggctgcaca atgatagact agagttggct taacctcagc
     7141 aaagactttt tcaaccattt cagaattagt gatatccatt tcggtcacat ccactgcaac
     7201 atagtccaca tttcgctcat ctagtaaata acgtagttcg gtaccaagtt gaccatttgc
     7261 acctgtaatt aagatcatat ttttctcctt gatagttctt atacttaatt atatcaaaaa
     7321 tatagaaaaa tcggttttta gtgaaccctt ttttggtata aactttgtta gtgaagcgca
     7381 agagagccga atagttatta ctttagaata tccttaaaag tatttttcag aatttaccaa
     7441 attaattaaa aaattcagaa aattatattg acatctctct gaaaagagtc tataatagag
     7501 agaaagtttt aaaggagaaa atgatgaaaa gttcaagact acttgccctt gcgggcgtga
     7561 cattattggc ggcgactact ttagctgcat gctctggatc aggttcaagc actaaaggtg
     7621 agaagacatt ctcatacatt tatgagacag accctgataa cctcaactat ttgacaactg
     7681 ctaaggctgc gacagcaaat attaccagta acgtggttga tggtttgcta gaaaatgatc
     7741 gctacgggaa ctttgtgccg tctatggctg aggattggtc tgtatccaag gatggattga
     7801 cttacactta tactatccgt aaggatgcaa aatggtatac ttctgaaggt gaagaatacg
     7861 cggcagtcaa agctcaagac tttgtaacag gattaaaata tgctgctgat aaaaaatcag
     7921 atgctcttta ccttgttcaa gaatcaatca aagggttgga tgcctatgta aaaggggaaa
     7981 tcaaagattt ctcacaagta ggaattaagg ctctggatga acagacagtt cagtacactt
     8041 tgaacaaacc agaaagcttc tggaattcta agacaaccat gggtgtgctt gcgccagtta
     8101 atgaagagtt tttgaattca aaaggagatg attttgccaa agctacggat ccaagtagtc
     8161 tcttgtataa cggtccttat ttgttgaaat ccattgtgac caaatcctct gttgaatttg
     8221 cgaaaaatcc gaactactgg gataaggaca atgtgcatgt tgacaaagtt aaattgtcat
     8281 tctgggatgg tcaagatacc agcaaacctg cagaaaactt taaagatggt agccttacag
     8341 cagctcgtct ctatccaaca agtgcaagtt tcgcagagct tgagaagagt atgaaggaca
     8401 atattgtcta tactcaacaa gactctatta cgtatctagt tggtacaaat attgaccgtc
     8461 agtcctataa atacacatct aagaccagcg atgaacaaaa ggcatcgact aaaaaggctc
     8521 tcttaaacaa ggatttccgt caggctattg cctttggttt tgatcgtaca gcctatgcct
     8581 ctcagttgaa tggacaaact ggagcaagca aaatcttacg taatatcttt gtgccaccaa
     8641 catttgttca agcagatggt aaaaactttg gcgatatggt caaagagaaa ttggtcactt
     8701 atggggatga atggaaggat gttaatcttg cagattctca ggatggtctt tacaatccag
     8761 aaaaagccaa ggctgaattt gctaaagcta aatcagcctt acaagcagaa ggtgtgactt
     8821 tcccaattca tttggatatg ccagttgacc agacagcaac tacaaaagtt cagcgcgtcc
     8881 aatctatgaa acaatccttg gaagcaactt taggagctga taatgtcatt attgatatcc
     8941 aacaactaca aaaagacgaa gtaaacaata ttacatattt tgctgaaaat gctgctggcg
     9001 aagactggga tttatcagat aatgtcggtt ggggtccaga ctttgccgat ccatcaacct
     9061 accttgatat catcaaacca tctgtaggag aaagtactaa aacatattta gggtttgact
     9121 caggggaaga taatgtagct gctaaaaaag taggtctata tgactacgaa aaattggtca
     9181 ctgaggctgg tgatgaggct acagatgttg ctaaacgcta tgataaatac gctgcagccc
     9241 aagcttggtt gacagatagt gctttgatta ttccaactac atctcgtaca gggcgcccaa
     9301 tcttgtctaa gatggtacca tttacaatac catttgcatt gtcaggaaat aaaggtgcaa
     9361 gtgaaccaat cttgtataaa tacttggaac ttcaagacaa ggcaatcact gtagatgaat
     9421 accaaaaagc tcaggaaaaa tggatgaaag aaaaagaaga gtctaataaa aaggctcaag
     9481 aagatctcgc aaaacatgtg aaataactgt tgcaaaatat aagaaaggat ttagtatttc
     9541 tcttgaatgc tgaatccttt ttatatttgt aaagaaagat tctaaatgta ctgaccccca
     9601 aaagttggag cctctttttg tcagaataga gaaaattttt gttaatttta cttgtttcct
     9661 attgctttct cagctattat ttgttatatt aaaagcataa ttatttttta tttatcaggg
     9721 ttaagcattg cactttcaga ggaaggagta ttttttaaaa agaaaatgta aacgcttgct
     9781 caaaaatgaa aggatttaga agtttatgaa taaaggatta tttgaaaaac gttgtaaata
     9841 tagtattcgg aaattttcat taggtgttgc ttctgttatg attggagctg cattctttgg
     9901 gacaagtccg gttcttgcag atagcgtgca gtctggttcc acggcgaact taccaactga
     9961 tttagctact gctcttgcaa cagcaaaaga gaatgatggg cgtgattttg aagcgcctaa
    10021 ggtgggagaa gaccaaggtt ctccagaagt tacagatgga cctaagacag aagaagaact
    10081 attagcactt gaaaaagaaa aaccggctga agaaaaacca aaagaggata aacctgcagc
    10141 tgctaaacct gaaacaccta agacggtaac ccctgaatgg caaacggtag agaaaaaaga
    10201 acaacaggga acagtcacta tccgagaaga aaaaggtgtc cgctacaacc aactatcctc
    10261 aactgctcaa aatgataacg caggcaaacc agccctgttt gaaaagaagg gcttgaccgt
    10321 tgatgccaat ggaaatgcaa ctgttgattt aaccttcaaa gaagattctg aaaagggcaa
    10381 atcacgcttt ggtgtcttct tgaaatttaa agatactaat aataatgttt ttgtcggtta
    10441 tgacaaggat ggctggttct gggagtataa atctccaaca actagcactt ggtatagagg
    10501 tagtcgtgtt gctgctcctg aaacaggatc aacaaaccgt ctctctatca ctctcaagtc
    10561 agacggtcag ctaaatgcca gcaataacga tgtcaatctc tttgacacag tgactctacc
    10621 agctgcggtc aatgaccatc ttaaaaatga gaagaagatt cttctcaagg cgggctctta
    10681 tgacgatgag cgaacagttg ttagcgttaa aacggataac caagaggggg taaaaacaga
    10741 ggatacccct gctgaaaaag aaacaggtcc ggttgttgac gatagcaagg tgacttatga
    10801 cacgattcag tctaaggtcc tcaaagcagt gattgaccaa gccttccctc gtgtcaagga
    10861 atacagcttg aatggacata ctttgccagg acaggtgcaa cagttcaacc aagtctttat
    10921 caataaccac cgaatcaccc ctgaagtcac ttataagaaa atcaatgaga caacagcaga
    10981 gtacttgatg aagcttcgcg atgatgctca cttaatcaat gcggaaatga cagtacgctt
    11041 gcaagttgtg gacaatcaat tgcactttga tgtgaccaag attgtcaacc acaatcaagt
    11101 cactccaggt caaaagatcg atgacgaaag aaaactactt tcttctatta gtttcctcgg
    11161 caatgcttta gtctctgttt ctagtgatca aactggtgct aagtttgatg gggcaaccat
    11221 gtcaaacaat acgcatgtca gcggagatga tcatatcgat gtaaccaatc caatgaaaga
    11281 cctagccaag ggttacatgt atggatttgt ttctacagat aagcttgctg ctggtgtttg
    11341 gagtaactct caaaacagct atggtggtgg ttcgaatgac tggactcgtt tgacagctta
    11401 taaagaaaca gtcggaaatg ccaactatgt aggaatccac agctctgaat ggcaatggga
    11461 aaaagcttat aagggcattg ttttcccaga atacacgaag gaacttccaa gggctaaggt
    11521 tgttatcact gaagatgcca atgcagacaa gaaagtcgat tggcaggatg gtgccattgc
    11581 ttatcgtagc attatgaaca accctcaagg ttgggaaaaa gttaaggata tcacagctta
    11641 ccgtatcgcg atgaactttg gttctcaagc acaaaaccca ttccttatga ccttggatgg
    11701 tatcaagaaa atcaatctcc acacagatgg tcttgggcaa ggtgttctcc ttaaaggata
    11761 tggtagcgaa ggccatgact ctggtcactt gaactatgct gatattggta agcgtatcgg
    11821 tggtgtcgaa gacttcaaga ccctaattga gaaggctaag aaatatggag ctcatctagg
    11881 tatccacgtt aacgcttcag aaacttatcc tgagtctaaa tacttcaatg aaaaaattct
    11941 ccgtaagaat ccagatggaa gctatagcta tggttggaac tggctagatc aaggtatcaa
    12001 cattgatgct gcctatgacc tagctcatgg tcgtttggca cgttgggaag atttgaagaa
    12061 aaaacttggt gacggtctcg actttatcta tgtggacgtt tggggtaatg gtcaatcagg
    12121 tgataacggt gcctgggcta cccacgttct tgctaaagaa attaacaaac aaggctggcg
    12181 ctttgcgatc gagtggggcc atggtggtga gtacgactct accttccatc actgggcagc
    12241 tgacttgacc tacggtggct acaccaataa aggtatcaac agtgccatca cccgctttat
    12301 ccgtaaccac caaaaagatg cttgggttgg ggactacaga agttatggtg gtgcagccaa
    12361 ctatccactg ctaggtggct acagcatgaa agactttgaa ggctggcaag gaagaagtga
    12421 ctacaatggc tatgtaacca acttatttgc ccatgacgtc atgaccaagt atttccaaca
    12481 cttcactgta agcaaatggg aaaatggtac accggtgact atgaccgata acggtagcac
    12541 ctataaatgg actccagaaa tgcgagtgga attggtagat gctgacaata ataaagtagt
    12601 tgtaactcgt aagtcaaatg atgtcaatag tccacaatat cgcgaacgta cagtaacgct
    12661 caacggacgt gtcatccaag atggttcagc ttacttgact ccttggaact gggatgcaaa
    12721 tggtaagaaa ctttctactg ataaggaaaa gatgtactac ttcaatacgc aggccggtgc
    12781 aacaacttgg acccttccaa gcgattgggc aaagagcaag gtttaccttt acaagctaac
    12841 tgaccaaggt aagacagaag agcaagaact aactgtaaaa gatggtaaaa ttactctaga
    12901 tcttctagca aatcaaccat acgttctcta tcgttcgaaa caaaccaatc ctgaaatgtc
    12961 atggagcgaa ggcatgcaca tctatgacca aggatttaat agtggaacct tgaaacactg
    13021 gaccatttct ggtgatgctt ctaaggcaga aattgtcaag tctcaagggg caaacgatat
    13081 gcttcgtatt caaggaaaca aagaaaaagt tagtctcact cagaaattaa ctggcttgaa
    13141 accaaatact aagtatgccg tttatgtcgg tgtcgataac cgtagtaatg ccaaggcaag
    13201 tatcactgtg aatactggtg aaaaagaagt gactacttat accaataagt ctctcgccct
    13261 caactatgtt aaggcctacg ctcacaatac acgtcgtgac aatgctacag ttgacgatac
    13321 aagttacttc caaaacatgt acgccttctt tacaactgga tcggacgtat caaatgttac
    13381 tctgacattg agtcgtgaag ctggtgatca agcaacttac tttgatgaaa ttcgtacctt
    13441 tgaaaacaat tcaagcatgt acggagacaa gcatgataca ggtaaaggca ccttcaagca
    13501 agactttgaa aatgttgctc agggtatctt cccatttgta gtgggtggtg tcgaaggtgt
    13561 tgaagataac cgcactcact tgtctgaaaa acacaatcca tatacacaac gtggttggaa
    13621 tggtaagaaa gtcgatgatg ttatcgaagg aaattggtca ctcaagacaa atggactagt
    13681 gagccgtcgt aacttggttt accaaaccat cccacaaaac ttccgttttg aagcaggtaa
    13741 gacctaccgt gtaacctttg aatacgaagc aggatcagac aatacctatg cttttgtagt
    13801 cggtaaggga gaattccagt caggtcgtcg tggtactcaa gcaagcaact tggaaatgca
    13861 tgaattgcca aatacttgga cagattctaa gaaagccaag aaggcaacct tccttgtgac
    13921 aggtgcagaa acaggcgata cttgggtagg tatctactca actggaaatg caagtaatac
    13981 tcgtggtgat tctggtggaa atgccaactt ccgtggttat aacgacttca tgatggataa
    14041 tcttcaaatc gaagaaatta ccctaacagg taagatgttg acagaaaatg ctctgaagaa
    14101 ctacttgcca acggttgcca tgactaacta caccaaagag tctatggatg ctttgaaaga
    14161 ggcggtcttt aacctcagtc aggccgatga tgatatcagt gtggaagaag cgcgtgcaga
    14221 gattgccaag attgaagctt tgaagaatgc tttggttcag aagaaaacgg ctttggtagc
    14281 agatgacttt gcaagtctta cagctcctgc tcaggctcaa gaaggtcttg caaatgcctt
    14341 tgatggcaat gtgtctagtc tatggcatac atcttggaat ggtggagatg taggcaagcc
    14401 tgcaactatg gtcttgaaag aaccaactga aatcacagga cttcgctatg ttccgcgtgg
    14461 atcaggttca aatggtaact tgcgagatgt gaaacttgtt gtgacagatg agtctggcaa
    14521 ggagcatacc tttactgcaa ctgattggcc agataacaat aagccaaaag acattgattt
    14581 tggtaagaca attaaggcta agaaaattgt ccttactggt accaagacat acggagatgg
    14641 tggagataaa taccaatctg cagcggaact tatctttact cgtccacagg tagcagaaac
    14701 acctcttgac ttgtcaggct atgaagcagc tttggttaag gctcagaaat taacagacaa
    14761 agacaatcaa gaggaagtag ctagcgttca ggcaagcatg aaatatgcga cggataacca
    14821 tctcttgacg gaaagaatgg tggaatactt tgcagattat ctcaaccaat taaaagattc
    14881 tgctacgaaa ccagatgctc caactgtaga gaaacctgag tttaaactta gatctttagc
    14941 ttccgagcaa ggtaagacgc cagattataa gcaagaaata gctagaccag aaacacctga
    15001 acaaatcttg ccagcaacag gtgagagtca atctgacaca gccctcatcc tagcaagtgt
    15061 tagtctagcc ctatctgctc tctttgtagt aaaaacgaag aaagactagt atttagtaaa
    15121 acctcttaac aagattacgg aagcagtctc tatcttttcc aatgaggttt atagtacaga
    15181 aaaagcctga gaagatgtct tctcaggctt ttgttaagca cataaataca atagtgctat
    15241 gacaaaatca cccagaaaaa tctgggtgat aaatgttatg gttgtgctgg ttgaggattc
    15301 tgattttgtt gatcaggggt tgtatttgat tgttgcgtat tattgttagg attggtagtc
    15361 gtactattat ttgtgcttgg agtggttgag ctagactgtg aagttgaact atctgatgat
    15421 gagcttgaac tttcagttga tgggggttgt tgtggagcag gtgagttcca cgtagaacga
    15481 gcaccatttt taaatacgaa ttctccattt cggaacaggc cgtctggcat cgtccaatct
    15541 ccaggttggt catcttctga tagatacgat atcattgagc gataaacctt agcagcaact
    15601 aggaaaccat ctccaacaat tggagttaaa cgatttgagt aaccagtcca tacagccata
    15661 gaatacttac gagtatagcc tacaaacatt tcatctggag ctacgtagcc agtattcttg
    15721 atatgttttt cgatttcgtc atcagtatag ttagaagtac ctgtcttacc tgcttgtgga
    15781 agccatggta ggtaagcacc acgtccggtt ccgtaagcta aaacagtttt catcatttcg
    15841 gtcatcatat aggcagtagt ttctttcata gctcgtgtac cagcatcaga aaattctttc
    15901 tcactaccat cactaaagac gattttattg atatacattg gtttgtggta aataccacca
    15961 ttagcaaagg cggcataagc agcagccatt ttttcactac ttgcaccgta atgtttgtta
    16021 gattctgttg tattacttga aatggcgtta gcatagtgta tgcttgggta atcgatacct
    16081 aagccattta ggaaagtttt ggctcgatct aaaccaacct tgtttaatgt ttcaactgct
    16141 gtaacattac gtgattgttg aagggcatat tgcagagtaa tattaccaaa atatgctcga
    16201 tcccagttgt agacaggtgt gcttgttccc ggatagttat aaggaatatc attaaccata
    16261 gttgcagtgg aatcatatac accgtattct atggcaggtg cataatcggt gattggtttc
    16321 attgttgaac cccagtcacg attggtttcc acagcttggt tggtaccaaa tgaaacgtta
    16381 cttgcttggt gacgagctcc aagttgggcg atgactttac cattggaaac atctacgacc
    16441 gtagatgcga cttgcaaatc atcgtctgga taggcaacgt attcgtctgt attgtaaata
    16501 tcccacagat gtttttgagc ttcttggtct acatttgtgt agacatccat cccagttgtg
    16561 agcaggttat agcctgtttc ttcttcaact tgattgatga cttccttgag gtaattatcc
    16621 atgtaagcag ggtaattact tgctgatttg agactttgta gtccatcagt aattggtgta
    16681 ttgactgctt tctcatactg ttcagcagag atgtagcctt gatttttcat ttcagataag
    16741 accaagtttc ggcggtcttg ggctgcttct ggatgtgaat aggggtcata ttggtttggt
    16801 gcttgaggca ttccagccag caaggctaac tgaggtaaac ttaaattatt gaggtcttta
    16861 ccatagtagt tttgagctgc tgtctgcatt ccatagtttc cattagacat gtagacctta
    16921 tttatatagt aggtcaagat ttcttgcttg gtggcttttt gttctaactg aatcgctaac
    16981 caagcttcct gagccttacg agaaatagtc tggtcggaag tcgaagttga aaagtaagtc
    17041 aacttaatca actgttgggt gagagttgat ccaccttgga gggaattgct ttgcagattg
    17101 cgcaagaaag ctcccaggat acggatggta tcaatccccc tgtggtcgaa gaagcgatgg
    17161 tcttcgatag aaacgattgc cttaaccaaa tctgtgggaa tatcattagc ttgggcattg
    17221 acgcggcgtt cagaacccaa gtcagcaatg agttgatttt tattgtcgta gattttacta
    17281 gaagttgttg caactagttt actctcggat aggctaggag ccttgctaac gtagtagaaa
    17341 aaaactcctc cgcctaagac aatggctgcg ataaccaagc ttaagaagct aatgctcaga
    17401 tacttgatta ggcgcagaat cgttggtttg ttcatcttgt tttaccacct aataaatgtt
    17461 ctttgataac attgagataa ggaatttgag ggaaggcacc agccttgatt tcatatccat
    17521 attctcgaat atattcaagt ggcattgatt tttgtccctt atcttgatga tagaagcgaa
    17581 tcaaatcgaa tgccggcaat aagtaggttt cttgctgaga agaaaagtga agaaggacaa
    17641 agcagattcc ttgttgggca aggacttgtt ccatatgctg aatctgatgt ggatgaaaat
    17701 ttttcatcgg aatcgcacgt ttttgttttg tttccttgac ttcaaagtcg atgtaatatc
    17761 cattataaac gccagaatag tccgtcgttg aagcttgtcg aaaataggct tcaacaatct
    17821 tggcacgact tcgttgtgga tagtccactt gtacgatttg aataggagtt ggtttcttat
    17881 gtatgacagc caagccctga gacaaatagt agtcgttggt agcattgatc atcttttcaa
    17941 aagacattcc tcgatttgcg aaatttttgg gttgagaaag agatttttgt cttttttgtg
    18001 atgaaacttt atgtggatag ttgaccataa ttctccttat tggtacaata acatcacttt
    18061 attatatcat aatttgcaca gaaagggtta aaaatggcta cagctttggt tttaggctat
    18121 tctgcttttg atttgggttt attttctgat aaggatcctc gtcttaaatt gattaaaaaa
    18181 gcgatacgta aagatttaga ggctatggca gcagatgggg tgtcttggct tgtgtttaca
    18241 ggaagtttgg gttttgaata ttgggtttta gaggttgctc aggagatgaa aaccgaatac
    18301 ggtttccagt tggccaccat ttttgctttt gaaacccatg gggaaaattg gaatgaaggc
    18361 aatcagatga aactgagtcg ctttaagcag gtagactttg tcaaatatgc ttatcctcgc
    18421 tatgaacaca aggggcagtt aagagattac cagcagtttt tgctggaaaa cacgactagt
    18481 tcctatcttt tttatgatga agaaaatgaa ataaaactag cttattttta ccaaaagatg
    18541 aaaaatcaag aggactattt tataaagaga ttaacatttg atcaattaaa tgaacttgct
    18601 gaaaattttt ccgaaaattg aagctttgac cttgattttt gtttgccttt ttttatataa
    18661 taatactagc aagcgagaat ggagagagac atggcaagta ttattttttc agcgaaagat
    18721 atttttgaac aagagtttgg acgtgaagtc cgtggctata ataaagtaga agttgacgag
    18781 tttttagacg atgtcatcaa ggactatgaa acctatgctg ccttggtcaa gtcacttcgt
    18841 caggaaattg cggatttgaa ggaagaatta actcgtaaac cgaaaccttc accagttcaa
    18901 gcagaacccc ttgaagcggc aattacaagt tctatgacga attttgatat tttgaaacgc
    18961 ctgaatagat tggaaaaaga agtttttggt aaacaaattt tagataactc agatttttaa
    19021 gtagttattt gagatgtgca atttttggat aatcgcgtga ggagaattgc ttctcatgag
    19081 gaaagtccat gctagcacag gctgtgatgc ctgtagtgtt tgtgctaggc gaaaccataa
    19141 gcctagggac gagaaatcgt tacggcagtt gaaatggcta agtccttgga taggccagag
    19201 taggcttgaa agtgccacag tgacggagtc tttctggaaa cagagagagt ggaacgcggt
    19261 aaacccctca agctagcaac ccaaattttg gtcggggcat ggagtacgcg gaaacgaacg
    19321 tagtattctg actgctatca gctagagctg ttagtggtag acagatgatt atcgaaggaa
    19381 gtggtcctag tcacttctgg aacaaaacat ggcttataga aaattgcata taggttgggg
    19441 ctgagaaatt ttctcaacct cattttttaa agtggacata tagaaaggtc ttgcaagact
    19501 gtaacatgaa aaaagaattt aatttaattg caactgtggc agcagggctt gaggctgtcg
    19561 ttggtcgtga agtgcgagag ttgggctacg attgtcaggt tgaaaatgga cgtgttcgtt
    19621 ttcaaggaga cgtgagagct attatcgaaa ccaacctttg gcttcgggca gcagatcgta
    19681 tcaaaattat cgtaggaacg ttcccagcta agacttttga agagctattt cagggagttt
    19741 tcgctttaga ttgggaaaat tatttaccac ttggagctcg gttcccgatt tcaaaagcta
    19801 aatgtgttaa gtccaaactt cacaatgagc ccagtgttca ggctatttct aagaaagctg
    19861 ttgtcaagaa attgcagaaa cactatgctc gcccagaagg ggttcctctg atggagaatg
    19921 gtccagagtt taagattgag gtctctattc tcaaagatgt ggcaactgtc atgattgata
    19981 cgaccgggtc tagcctcttt aaacgtggtt atcgtaccga aaaaggtggc gctcctatca
    20041 aggaaaatat ggcagcagcc attttacaac tttctaactg gtatccagac aagcctttga
    20101 ttgatccgac ctgtggttcg gggactttct gtattgaggc agttatgatt gctagaaaga
    20161 tggcgccagg tcttcgtcgc tcttttgcat ttgaggaatg gaactggatc agcgatcgct
    20221 tgattcaaga agtgcgcaca gaagcggcta aaaaagtaga ccgtgagctt gagctggata
    20281 tcatgggctg tgatattgat gctcgcatgg tggaaattgc taaggccaat gctcaggcag
    20341 ctggtgttgc aggagacatt acttttaagc agatgcgcgt gcaggattta cgttccgata
    20401 aaatcaatgg agtaatcatt tccaatccgc cttatggtga acgtttgtca gatgatgcag
    20461 gggtgaccaa gctctatgct gagatggggc aagtatttgc accgctgaaa acttggagca
    20521 aatttatcct gactagtgat gaagcttttg aaagcaagta tggtagccaa gcagataaga
    20581 agcgtaagtt atacaacgga accttgaaag tggatctata tcaatatttt ggtcagcgtg
    20641 tcaaacggca agaggtaaaa tagaaaggga tactcatgag taaaaaaaga cgaaatcgtc
    20701 ataaaaaaga aggtcaagaa ccgcaatttg attttgatga agcaaaagag ctaacagttg
    20761 gtcaagctat tcgtaaaaat gaagaagtgg aagcaggagt cttgcctgag gattccattt
    20821 tggacaagta tgttaagcaa cacagagatg aaattgaggc ggataagttt gcgactcgtc
    20881 aatacaaaaa agaggagttc gttgaaactc agagtctgga tgatttaatt caagagatgc
    20941 gtgaggctgt agagaagtca gaagcttctt cggaggaagt tccatcttct gaagacatct
    21001 tactaccctt gcctctggac gatgaggagc aaggcttgga tcctctattg ctagatgatg
    21061 aaaatccaac agaaatgact gaagaagtgg aagaggagca aaacctttct cgtctggatc
    21121 aagaggactc agaaaagaaa agtaaaaaag gctttatttt gaccgttttg gcgcttgtat
    21181 cagtaattat ttgtgtcagt gcttattatg tctaccgtca agtggctcgt tcgaccaagg
    21241 aaattgaaac ttctcaatca attacagcca atcaatcgga tgtggatgat tttaatacac
    21301 tttatgacgc cttttacaca gatagcaata aaacggcttt gaaaaatagc cagtttgata
    21361 aactgaatca actcaagacc ttacttgata agctggaagg tagtcgtgaa catacgcttg
    21421 ccaaatctaa atatgatagt ctagcaacgc aaatcaaggc tattcaagat gtcaatgctc
    21481 aatttgagaa accagctatt gtggatggtg tgttggatac caatgccaaa gccaaattgg
    21541 atgctaaatt tacggatatt aaaactggaa atacggagct tgataaagtg ctagataagg
    21601 ctatcagtct tggtaagagc cagcaaacaa gtacttctag ctcaagttca agtcaagcaa
    21661 gttcaaatac gactagtgag ctaaaaccaa gtagttcaaa tgagactaga agtagtcgca
    21721 gtgaagtcaa tatgggtctc tcgagtgcag gggttgctgt tcaaagaagt gccagtcgtg
    21781 ttgcctataa tcagtctgct attgatgata gtaataactc tgcctgggat tttgcggatg
    21841 gtgttttgga acaaattcta gcaacttcac gttcacgtgg ctatatcact ggagaccaat
    21901 atatccttga acgtgtcaat atcgttaacg gcaatggtta ttacaacctc tataagccag
    21961 atggaaccta tctctttacc cttaactgta agacaggata ttttgtcgga aatggcgctg
    22021 gtcatgcgga tgacttggac tactaagcag tcgttacaaa attctttctt ttcaaaagta
    22081 aaaatgataa aataaaacaa atgaaacaag aggagtgtca aatgacaaaa gctaactttg
    22141 gtgttgtagg tatggccgta atgggtcgta accttgccct taatattgaa tctcgtggtt
    22201 acacagttgc tatctacaac cgtagtaaag aaaaaacgga agatgtgatt gcttgccatc
    22261 ctgaaaagaa ctttgtacca agctatgacg ttgaaagttt tgtaaactca atcgaaaaac
    22321 ctcgtcgtat catgctgatg gttcaagctg gacctggtac agatgctact atccaagccc
    22381 ttcttccgca ccttgacaag ggtgatatct tgattgacgg aggaaacact ttctacaaag
    22441 ataccatccg tcgtaatgaa gaattggcaa actcaggtat caactttatc ggtactggag
    22501 tttctggtgg tgaaaaaggt gcccttgaag gtccttctat catgcctggt ggacaaaaag
    22561 aggcctacga attggttgct gatgttcttg aagaaatctc agctaaagca ccagaagatg
    22621 gcaaaccatg tgtgacttac atcggccctg atggagctgg tcactatgtg aaaatggttc
    22681 acaatggtat tgagtacggt gatatgcaat tgatcgcaga aagctatgac ttgatgcaac
    22741 acttgctagg cctttctgca gaggatatgg ctgaaatctt tactgagtgg aacaagggtg
    22801 aattggatag ctacttgatc gaaatcacag ctgatatctt gagccgtaaa gacgatgaag
    22861 accaagatgg accaatcgta gactacatcc ttgatgctgc aggtaacaag ggaactggta
    22921 aatggacgag ccaatcatct cttgaccttg gtgtaccatt gtcactgatt actgagtcag
    22981 tgtttgcacg ctacatttca acttacaaag aagaacgtgt acatgctagc aaggtgcttc
    23041 caaaaccagc tgccttcaac tttgaaggag acaaggctga attgattgaa aaaatccgtc
    23101 aagcccttta cttctcaaaa atcatttcat acgcacaagg atttgctcaa ttgcgtgtag
    23161 cctctaaaga aaacaactgg aacttgccat ttgcagatat cgcatctatc tggcgtgatg
    23221 gctgtatcat ccgttctcgt ttcttgcaaa agattacaga tgcttacaac cgcgatgcag
    23281 atcttgccaa ccttcttttg gacgagtact tcttggatgt tactgctaag tatcaacaag
    23341 cagtgcgtga tatcgtagct cttgcggttc aagctggtgt gccagtgcca actttctcag
    23401 cagctattac ttactttgat agctaccgtt cagctgacct tccggctaac ttgatccaag
    23461 cacaacgtga ctactttggt gctcacactt accaacgtaa agacaaagaa ggaaccttcc
    23521 actactcttg gtatgacgaa aaataagtag gtcagccatg gggaaacgga ttttattact
    23581 tgagaaagaa cgaaatctag ctcatttttt aagtttggaa ctccagaaag agcagtatcg
    23641 ggttgatctg gtagaggagg ggcaaaaagc cctttccatg gctcttcaga cagactatga
    23701 tttgatttta ttgaacgtta atctgggaga tatgatggct caggattttg cagaaaaatt
    23761 gagtcgaact aaacctgcct cagtcatcat gattttagat cattgggaag acttgcaaga
    23821 agagctggaa gttgttcagc gttttgcagt ttcatacatc tataagccag tctttatcga
    23881 aaatctggta gcgcgtattt cggcgatctt ccgaggtcgg gacttcattg atcaacactg
    23941 cagtctgatg aaagttccaa ggacctaccg caatcttagg atagatgttg aacatcacac
    24001 ggtttatcgt ggtgaagaga tgattgctct gacccgccgt gagtatgacc ttttggcgac
    24061 acttatggga agcaagaaag tattgactcg tgagcaattg ttggaaagtg tttggaagta
    24121 tgaaagtgcg accgagacaa atatcgtaga tgtctatatc cgctatctac ggagcaagct
    24181 tgatgttaaa ggacaaaaaa gctacattaa aaccgtgcgt ggtgttggtt acaccatgca
    24241 agaatagaaa agcagttgca gttgtgtaac tgcttttttg aggagttttt atatattgac
    24301 atgcagtcgg gtctttgcta caatcgtttt aggaggatat ataaatgaaa cttttgaaaa
    24361 aaatgatgca agttctacta gcagtctttt tctttggttt gctagctaca aatacggtat
    24421 ttgcgaatac cacaggtggc cgatttgttg ataaggataa tagaaaatat tatgtaaaag
    24481 atgatcataa agcaatctat tggcataaaa tagacggtaa aacttactat tttggtgata
    24541 ttggagagat ggttgtcggt tggcaatact tagaaattcc tggaacaggt tatcgtgatg
    24601 atttatttga taatcgtcca gtcttcgaaa ttggccttca ggagaagtgg tactattttg
    24661 gacaagatgg tgctttgcta gaacaaacag ataaacaagt actagaggca aaaacgtctg
    24721 aaaatacagg aaaagtatac ggtgaacaat atcctctatc tgctgaaaag agaacttatt
    24781 attttgataa taattatgct gtaaagacag gctggattta tgaagacggc aattggtatt
    24841 atttaaataa gctaggaaat tttggtgatg attcttacaa tccactacca attggtgaag
    24901 ttgctaaggg ttggactcaa gattttcatg ttactattga cattgataga agcaaacctg
    24961 ctccatggta ctacctagat ccaacaactg gtattatgca aacaggttgg caatatctag
    25021 gtaataagtg gtactacctc cgttcctcag gagcaatggc cactggctgg tatcaggcag
    25081 gtaccacttg gtattattta gaccagccaa atggcgatat gaaaacaggt tggcaaaacc
    25141 ttgggaacaa atggtactat ctccgttcct caggagctat ggcaactggt tggtatcaag
    25201 atggttcaac ttggtactac ctaaatgcag gtaatggaga catgaagaca ggttggttcc
    25261 aggtcaatgg caactggtac tatgcttata gctcaggtgc tttggcagtg aatacgaccg
    25321 tagatggcta ttctgtcaac tataatggcg aatgggttcg gtaatgacag ggcgcttata
    25381 attatattag aacactcgct taatcaaaga agtgactttg ttgtacttga cctgacgatt
    25441 ggggagatta aaagcatgtg aaatctacac atgctttttc gttagttatg agtgttgaac
    25501 ttgactaacc attgacaaaa gataagagca atcaaaataa gatacaaaaa tatcaatgct
    25561 aactgcaccg aaacgcccga tgctatggat agggctaata gggagagcag ggacggggcg
    25621 agaatgtcta ctgtgctcag agcagagccc accgtcccca tcttgtcact ggggatatgg
    25681 gcaaagacag ctgcttgtag gcgagggctg agaatgccga taatcgtaga actgatgaaa
    25741 ctggtcacga aaattacgat ataggcttga caaaggatac tagttattag agccaatagg
    25801 gaaatctcac agaaaaccaa gaggtgcgtg aaacggatat ttttaaatag attactgctg
    25861 gtcatattgc caaggatagc tccacaagac atgatgatgg agagcagggc gaggagttgc
    25921 ccaatgctca gttgtgctag tgtctgttgg atgaagcgga gggcaatcag ccgaggggac
    25981 acatccaaga tggcaatcat actggtcgtc agaaacagta gtatgacggt atcttttaac
    26041 ttcagtagca cagccagcga ctgtttaaga tgttgaaaat atttcttaaa actcagtgct
    26101 gtatgtgaca tttcaatcct tttttcaacc tcatacaagg tatgtcgaat aacatacagg
    26161 cccaaaaagg caatgacaaa agtcagagtg ttgataaggg aaatagtttg aatacttata
    26221 acattgataa ggaatgcgcc agccagattg gcgacaatgc ggacaaccct catcagagac
    26281 tgcctgaacc ccatggcatc atgcaggtcg tccttaatta cactgatgta gagggcgttc
    26341 atcatgtagg cagacaggta gctcaaggtg tcagagatga ggttgatgat gacaatcata
    26401 atgactgaaa ctaatgaaaa gggcgacaag acgagaaata ctgtcaaaat agcgtagagc
    26461 aggattttga ttttggcaat acagagtgcg tgtttgactc tattttcttg aaaatctcct
    26521 agaatcccga gaaagagttg cgatagtagg ggaaccatct ctgaaatgga aatcagtaaa
    26581 atcgctagcg gagcgaaatt gtactgagcc acataattga taatggcgag gtagaaaata
    26641 ctgtcgccga atgatgaaaa acagctgttt agcagcaact gtctatatat gttgtttgtc
    26701 caaaataatt tcatacattt ctccttatgt ctgcacatcg aatgggaatt tattatttaa
    26761 tagacaccaa tataccccca tgcttcctat tccgaagtca aacaaatctg ctttaccact
    26821 atctccttga aacatcagta aaccgtgatc atctcgttca gaacatgcta aaattacctg
    26881 ttggattttt tcatcagtaa tttgttttga ttgtagacag tggtttgtag taagctagtt
    26941 attccgtggc aatatcctgt catcattttt agatgatggt taaaaacaaa ttcttgatat
    27001 ttactaataa tatctttgtt tccgtcacaa tcgtacatac aaagatataa gattattccg
    27061 gaaattcctt tgcaccaaga aagttgtgaa tttcctaaat tttcagtatt agaagtaact
    27121 ttttctaata atttttttaa ttcagtatgg aatgtatgga gatcattata gaacatagaa
    27181 ggttctaaga ctttagaata ggcaaataaa gcctatgcaa ttccacaata tccatgagca
    27241 aagctatagt ctaaaatgct ttctttggct atatctcttt gtaggaaata atgctaaatt
    27301 tcccctatac tattgtggat gaaaatttta agagtattgt cattggtaaa ttgatagtat
    27361 tttattaatg ataataggac accagatttt cccaatgcaa agtctatttc ctctagagta
    27421 tcataattct ctattaattt cttagcggag acgtttgcta attgtagata gtattgattt
    27481 ttactgatag aaaataaatg taggagtaac catagatagc ctgcatcacc aaatagcagt
    27541 gagtattgat atttatatgt gtgtgtcgtt ctaattgtca ctgccttctt gatgatagag
    27601 agtattttag aatccagttc tggggggtac aatttattta gaggaaacag tagtccagct
    27661 attccgtgtt ggaatgataa attacttacg aaatttccaa attctgttga agaagtgatc
    27721 cttccttcag aatttacagt tttatctagt aaaaatcgta gaacactatt acattctgtt
    27781 ttgtaatcat atttatgttc ctctattttt ttaattttga ctaaattatt tgtttgactt
    27841 aaatttagta gacattgtaa ccaaaatagt tgctcatctg tgagctgacc ttgagtatgt
    27901 gatagttcta gtaattgaat aggatccttt agttagattc aatcaatcta taacacaaca
    27961 acataataat acttttagga taacttgtca aata
//
LOCUS       DAVLXH010000023        27930 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00028199
            SAMN33607166-rid17955573.denovo.023, whole genome shotgun sequence.
ACCESSION   DAVLXH010000023 DAVLXH010000000
VERSION     DAVLXH010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607166
            Sequence Read Archive: SRR23725544
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 27930)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27930)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721421.1
            Genome Coverage       :: 115x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:42:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,210
            CDSs (total)                      :: 2,161
            Genes (coding)                    :: 2,023
            CDSs (with protein)               :: 2,023
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 73 of 138
            Pseudo Genes (incomplete)         :: 60 of 138
            Pseudo Genes (internal stop)      :: 40 of 138
            Pseudo Genes (multiple problems)  :: 31 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27930
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607166-rid17955573.denovo.023"
                     /strain="AUSMDU00028199"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1349"
     gene            517..900
                     /locus_tag="VYO11_001114"
     CDS             517..900
                     /locus_tag="VYO11_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein"
                     /protein_id="HEV1595697.1"
                     /translation="MKYRLFFVIFLSSVLDILLGTFLQISIVSIGWLVLYSGLFEAGV
                     FLLANKGVAVKIKEVDIRNRFKFIFGKTLWFQILLLIFLIIKLYLGLDARLILFYGHI
                     FIVFNALMYLLSSSQVSLKKNKLSS"
     gene            952..1641
                     /locus_tag="VYO11_001115"
     CDS             952..1641
                     /locus_tag="VYO11_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000760553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV1595698.1"
                     /translation="MKKYQLLFKISAVFSYLFFVFGLSQLTLIVQNYWQFSSQIGNLF
                     WIQNILSLLFIGVMIVVLVKTGHGYLFRIPRKKWLWYSILTVLVVVLQISFNVQTAKH
                     VQSTAEGWAVLIGYSGTNFAELGIYIALFFLVPLMEELIYRGLLQHAFFKHSRFGLDL
                     LLPSILFALPHFSSLPSLLDIFVFATVGIIFAGLTRYTKSIYPSYAVHVINNIVATFP
                     FLLTFLHRVLG"
     gene            1683..1916
                     /locus_tag="VYO11_001116"
     CDS             1683..1916
                     /locus_tag="VYO11_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1595699.1"
                     /translation="MYKHLFFLDSKTLDRLTPYILVLASDTIAFNVFVLTFVSAVVFN
                     FLNSMLALMAIFIGAGYVVGFWLLILNENQRAN"
     gene            2067..2678
                     /locus_tag="VYO11_001117"
     CDS             2067..2678
                     /locus_tag="VYO11_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV1595700.1"
                     /translation="MEFFDKFHALCFGFLVLIIVITVPYTINHGGFFQNESALILVSL
                     LVTSLSVAYARKFEMISFGMLSKKQLLLFIAIFLLSVLETLVYIHFFAVSSGSGVQHL
                     AEVSRGISLSLILTTSVFGPIQEELIFRGLLQGAVFDNSWLGLVLTSSLFSFMHGPSN
                     VPSFIFYLLGGLLLGFAYKKSQNLWVSTLVHMLYNSWPLLYYL"
     gene            2839..3633
                     /locus_tag="VYO11_001118"
     CDS             2839..3633
                     /locus_tag="VYO11_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000363010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HEV1595701.1"
                     /translation="MDLGDNELTLTPIPGKSGKAYMGSYPDGKRIFVKMNTSPILPGL
                     AREQIAPQLLWSRRLADGRDMCAQEWLTGKILTPYDMNRKQIVNILTRLHRSRPLMTQ
                     LSRLGYAMETPVDLLQSWQETAPDALRKNHFISEVMADLRQTIPGFREDHATIVHGDV
                     RHSNWIETDSGLIYLVDWDSVRLTDRMFDVAHMLCHYISEHQWKEWLTYYGYKYNQTV
                     LSKLYWYGQLSYLSQISKYYMNQDLENVNREIHGLRHFRDKYGKRR"
     gene            3630..4265
                     /gene="trmB"
                     /locus_tag="VYO11_001119"
     CDS             3630..4265
                     /gene="trmB"
                     /locus_tag="VYO11_001119"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001266107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HEV1595702.1"
                     /translation="MRVRNRKGATELLEANPQYVVLNPLEAKAKWRDLFGNDNPIHVE
                     VGSGKGAFVSGMAKQNPDINYIGIDIQKSVLSYALDKVLEAGVSNIKLLWVDGSDLTD
                     YFEDGEIDRLYLNFSDPWPKKRHEKRRLTYKTFLDTFKRILPENGEIHFKTDNRGLFE
                     YSLVSFSQYGMKLNGVWLDLHASDFEGNVMTEYEQKFSNKGQVIYRVEAEF"
     gene            4392..4871
                     /gene="rimP"
                     /locus_tag="VYO11_001120"
     CDS             4392..4871
                     /gene="rimP"
                     /locus_tag="VYO11_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HEV1595703.1"
                     /translation="MDAIATIVELVREVVEPVIEAPFELVDIEYGKIGSDMILSIFVD
                     KSEGITLNDTADLTEMISPVLDTIKPDPFPEQYFLEITSPGLERPLKTKDAVAGAVGK
                     YIHVGLYQAIDKQKVFEGTLLAFEEDELTMEYMDKTRKKTVQIPYSLVSKARLAVKL"
     gene            4915..6051
                     /gene="nusA"
                     /locus_tag="VYO11_001121"
     CDS             4915..6051
                     /gene="nusA"
                     /locus_tag="VYO11_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HEV1595704.1"
                     /translation="MSKEMLEAFRILEEDKGIKKEDIIDAVVESLRSAYRRRYGQSDS
                     VAIDFNEKTGDFTVYTVREVVDEVFDSRLEISLKDALAINSAYELGDKIKFEEAPAEF
                     GRVAAQSAKQTIMEKMRKQTRAITYNTYKEHEQEIMSGTVERFDNRFIYVNLGSIEAQ
                     LSKQDQIPGEVFASHDRIEVYVYKVEDNPRGVNVFVSRSHPEMIKRLMEQEIPEVYDG
                     TVEIMSVAREAGDRTKVAVRSHNPNVDAIGTIVGRGGANIKKITSKFHPARYDAKNDR
                     MVPIEENIDVIEWVADPAEFIYNAIAPAEVDQVIFDENDSKRALVVVPDNKLSLAIGR
                     RGQNVRLAAHLTGYRIDIKSASEFEAMEDAASVELEVENDTVEE"
     gene            6073..6366
                     /locus_tag="VYO11_001122"
     CDS             6073..6366
                     /locus_tag="VYO11_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000857559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HEV1595705.1"
                     /translation="MKTRKIPLRKSVVSNEVIDKRDLLRIVKNKEGQVFIDPTGKANG
                     RGAYIKLDNAEALEAKKKKVFNRSFSMEVEESFYDELIAYVDHKVKRRELGLE"
     gene            6359..6658
                     /locus_tag="VYO11_001123"
     CDS             6359..6658
                     /locus_tag="VYO11_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HEV1595706.1"
                     /translation="MNKQKISNLLGLAQRAGRIISGEELVVKAIQDGKAKLVFLAHDA
                     GPNLTKKIQDKSHYYQVEIVTVFSTLELSIAVGKSRKVLAVTDAGFTKKMRSLME"
     gene            6675..9467
                     /gene="infB"
                     /locus_tag="VYO11_001124"
     CDS             6675..9467
                     /gene="infB"
                     /locus_tag="VYO11_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HEV1595707.1"
                     /translation="MSKKRLYEIAKELGKESKEVVARAKELGLDVKSHSSSVEEAVAA
                     KIAASFKPAAAPKVEAKPAAPKVSAEKKAEKSEPAKPAVAKEEAKPAEPVAPKTEKVA
                     AKPQSRNFKAEREARAKEQAERRKQNKGNNRDQQQNGNRQKNDGRNGGKQGQSNRDNR
                     RFNDQAKKQQGQQKRRNERRQQEDKRSNQVAPRIDFKARAAALKAEQNAEYARSSEER
                     FKQYQAAKEALAQANKRKEPEEIFEEAAKLAEQAQQVQAVVEVVPEKKEPAVDTRRKK
                     QARPDKNRDDYDHEEDGPRKQQKNRSSQNQVRNQKNSNWNNNKKNKKGNNKNNRNQTP
                     KPVTERKFHELPTEFEYTDGMTVAEIAKRIKREPAEIVKKLFMMGVMATQNQSLDGET
                     IELLMVDYGIEAKQKVEVDNADIERFFVEDGYLNEDELVERPPVVTIMGHVDHGKTTL
                     LDTLRNSRVATGEAGGITQHIGAYQIVENGKKITFLDTPGHAAFTSMRARGASVTDIT
                     ILVVAADDGVMPQTIEAINHSKAANVPIIVAINKIDKPGANPERVIGELAEHGVMSTA
                     WGGDSEFVEISAKFNQNIEELLETVLLVAEIQELKADPTVRAIGTVIEARLDKGKGAV
                     ATLLVQQGTLNVQDPIVVGNTFGRVRAMTNDLGRRVKVAGPSTPVSITGLNEAPMAGD
                     HFAVYEDEKSARAAGEERAKRALMKQRQATQRVSLENLFDTLKAGELKSVNVIIKADV
                     QGSVEALSASLQKIDVEGVKVTIVHSAVGAINESDVTLAEASNAFIVGFNVRPTPQAR
                     QQAEADDVEIRLHSIIYKVIEEMEEAMKGMLDPEFEEKVIGEAVIRETFKVSKVGTIG
                     GFMVINGKVARDSKVRVIRDGVVIYDGELASLKHYKDDVKEVTNGREGGLMIDCYNDI
                     KMDDVIEAYVMEEIKR"
     gene            9718..10068
                     /gene="rbfA"
                     /locus_tag="VYO11_001125"
     CDS             9718..10068
                     /gene="rbfA"
                     /locus_tag="VYO11_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HEV1595708.1"
                     /translation="MANHFRTDRVGMEIKREVNEILQKKVRDPRVQGVTITDVQMLGD
                     LSVAKVYYTILSNLASDNQKAQIGLEKATGTIKRELGRNLKLYKIPDLTFVKDESIEY
                     GNKIDEMLRNLDKN"
     gene            10347..11126
                     /locus_tag="VYO11_001126"
     CDS             10347..11126
                     /locus_tag="VYO11_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1595709.1"
                     /translation="MAEQDLAMQVLQQVVKLPVVKVDRSKFLVDKFSKELGPQDIPTL
                     LEQGPTSLLSQEILDRVANACIRDNVLLASGTSVLAGLPGGLAMAITIPADVAQFYGF
                     SLKLAQELGYIYGYEDLWASRDELSEDAQNTLLLYLGVMLGVNGTAALLRAGGITIAK
                     QVMKTVPNKALTKTLWYPILKKVLRIFGVNLTKGGLAKGMGKFIPILGGIISGGLTFA
                     TMKPMGESLQKELSKLVNYSEVQYQEDVETIRKEAEIIKGE"
     gene            11128..11310
                     /locus_tag="VYO11_001127"
     CDS             11128..11310
                     /locus_tag="VYO11_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1595710.1"
                     /translation="MNPIKAFAKIYGNYFLTVQGVKVMKTIKKDDNAVVGLGKLFIAD
                     KLMDTARWLIKPEDKK"
     gene            11307..11447
                     /locus_tag="VYO11_001128"
     CDS             11307..11447
                     /locus_tag="VYO11_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000668195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1595711.1"
                     /translation="MKFFWGLLAIIFIKPIIGIVKFFWMIISFAVQLLFYKILDWFFK
                     LI"
     gene            complement(11655..11729)
                     /locus_tag="VYO11_001129"
                     /pseudo
     CDS             complement(11655..11729)
                     /locus_tag="VYO11_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829418.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            11760..11993
                     /locus_tag="VYO11_001130"
     CDS             11760..11993
                     /locus_tag="VYO11_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006144975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1858 domain-containing protein"
                     /protein_id="HEV1595712.1"
                     /translation="MDNIIDVSIPVAEVVDKHPEVLEILVELGFKPLANPLMRNTVGR
                     KVSLKQGSKLAGTPMDKIVRTLEANGYEVIGLD"
     gene            11993..13327
                     /locus_tag="VYO11_001131"
     CDS             11993..13327
                     /locus_tag="VYO11_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000752887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF438 domain-containing protein"
                     /protein_id="HEV1595713.1"
                     /translation="MADERIHVLRDILLELHNGASPESVQERFDATFAGVSAIEISLM
                     EHELMNSDSGVTFEDVMELCDVHANLFKNAIKGVEVSDTEHPGHPVRVFKEENLALRA
                     ALIRIRRLLDTYESMEDEEMLAEMRKGLVRQMGLVGQFDIHYQRKEELFFPIMERYGH
                     DSPPKVMWGVDDQIRELFQTALTTAKSLPEVSISSVKEAFEAFATEFESMIFKEESIL
                     LMILLESFTQDDWLQIAEESDAYGYAIIRPSEKWVPERQIFIEEKIAEEPVQLDTAEG
                     QVQQVIDTPEGHFTITFTPKEKEAVLDRHSQQAFGNGYLSVEQANLILNHLPMEITFV
                     NKEDIFQYYNDNTPADEMIFKRTPSQVGRNVELCHPPKYLDKVKAIMKGLREGTKDKY
                     EMWFKSESRGKFVHITYAAVHDEDGEFQGVLEYVQDIQPYREIDTDYFRGLE"
     gene            13337..13591
                     /locus_tag="VYO11_001132"
     CDS             13337..13591
                     /locus_tag="VYO11_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1912 family protein"
                     /protein_id="HEV1595714.1"
                     /translation="MSYEQEFMKEFEAWVNTQIMINDMAHKESQKVYEEDQDERAKDA
                     MIRYESRLDAYQFLLGKFENFKVGKGFHDLPEGLFGERNY"
     gene            13687..14082
                     /locus_tag="VYO11_001133"
     CDS             13687..14082
                     /locus_tag="VYO11_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HEV1595715.1"
                     /translation="MSKKLNRKKQLRNGLRRAGAFSSTVTKVVDETKKVVKRAEQSAS
                     AAGKAVSKKVEQAVEATKEQAQKVANSVEDFAANLGGLPLDRAKTFYDEGIKSASHFK
                     NWTEKELLDLKGIGPATIKKLKENGIKFK"
     gene            14494..14943
                     /locus_tag="VYO11_001134"
     CDS             14494..14943
                     /locus_tag="VYO11_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase"
                     /protein_id="HEV1595716.1"
                     /translation="MIGVVARENAAEQIKQYQKFTVNISDETSMLAMEQAGFISHQEK
                     LERLGVHYEISERTQTPILDACPLVLDCRVDRIVEEDGICHIFAKILERLVVPELLDE
                     KGHFKNQLFAPTYFMGDGYQRVYRYLDKRVDMKGSFIKKARKKDGKN"
     gene            14930..15490
                     /locus_tag="VYO11_001135"
     CDS             14930..15490
                     /locus_tag="VYO11_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000124561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1595717.1"
                     /translation="MARTELPDKIETECLVLRVRTVADAEDIFDYASLPEVAYPAGFP
                     PVKTLEDEIYYLEHILPERNQKENLPAGYGIVVKGTDKIVGSVDFNHRHEDDVLEIGY
                     TLHPDYWGRGYVPEAARALIDLAFKDLGLHKIELTCFGYNLQSQRVAEKLGFTLEARI
                     RDRKDAQGNCCDDLRYAFLKSEWEVI"
     gene            15490..16068
                     /locus_tag="VYO11_001136"
     CDS             15490..16068
                     /locus_tag="VYO11_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000550018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEV1595718.1"
                     /translation="MHLFIIGAPASGKMTIGQELSRLTDATLFYNHQAIDFALEIYQD
                     YTEEMWEFVRGITFSFLGASARNQRSVILTDVIDFSNQYHLIYLKQIQSLLDDYHQEI
                     LFVELETSLEECIRRNRTENRLKYKPLKRHIEVSEREIIETAETLQLNSQHQPNELNH
                     YFKINNTNLSAEEAAKQIQNKINKIEKGHTHV"
     gene            16061..18712
                     /locus_tag="VYO11_001137"
     CDS             16061..18712
                     /locus_tag="VYO11_001137"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009732359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HEV1595719.1"
                     /translation="MSKELSPKYNPAEVEAGRYQKWLDADVFKPSGDQKAKPYSIVIP
                     PPNVTGKLHLGHAWDTTLQDIIIRQKRMQGFDTLWLPGMDHAGIATQAKVEERLRGEG
                     ISRYDLGRESFLTKVWEWKDEYATTIKEQWGKMGLSVDYSRERFTLDEGLSKAVRKVF
                     VDLYKKGWIYRGEFIINWDPAARTALSDIEVIHKDVEGAFYHMNYMLEDGSRALEVAT
                     TRPETMFGDVAVAVNPEDPRYKDLIGKNVILPIANKLIPIVGDEHADPEFGTGVVKIT
                     PAHDPNDFLVGQRHNLPQVNVMNDDGTMNELAFEFSGMDRFEARKAVVAKLEEIGALV
                     KIEKRVHSVGHSERTGVVVEPRLSTQWFVKMDQLAKNAIANQDTEDKVEFYPPRFNDT
                     FLQWMENVHDWVISRQLWWGHQIPAWYNADGEMYVGEEAPEGDGWTQDEDVLDTWFSS
                     ALWPFSTMGWPEVDSEDFKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGRQPFQNVL
                     IHGLIRDEQGRKMSKSLGNGIDPMDVIEKYGADALRWFLSNGSAPGQDVRFSYEKMDA
                     SWNFINKIWNISRYILMNNEGLTLDVAHDNVTKVATGEAGNVTDRWILHNLNETIAKV
                     TENFDKFEFGVAGHILYNFIWEEFANWYVELTKEVLYSDNEDDKVITRSVLLYTLDKI
                     LRLLHPIMPFVTEEIFGQISEGSIVTAAYPTVNLAFEDLAAHTGVESLKDLIRAVRNA
                     RAEVNVAPSKPITILVKTSDSDLEAFFNSNVNYIKRFTNPEHLEIASTIPAPELAMSS
                     VITGAEIYLPLADLLNVEEELARLDKELAKWQKELDMVGKKLFNERFVANAKPEVVQK
                     ERDKQADYQAKYDATVARIDEMKKLVK"
     gene            18793..18957
                     /locus_tag="VYO11_001138"
     CDS             18793..18957
                     /locus_tag="VYO11_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HEV1595720.1"
                     /translation="MGKIVAIDLFSGAGGTTSGLKKSGIDVQVAVEIDSVAVKTYKLN
                     NPEVSVIDME"
     gene            19008..20387
                     /locus_tag="VYO11_001139"
     CDS             19008..20387
                     /locus_tag="VYO11_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEV1595721.1"
                     /translation="MSEYWFSTNVDQIDEVDGKQCLIYSYYNVKASRNVEVLKGRSGT
                     KKGLDYWEPYAPQKQYEMERLPKNKYIGSSSTDRWDGIEKNVVFCDCKEYVSAFDLFF
                     YHYNFKKISTQRSKQDFIRLRSKPVADILKNNTSSYTRYKKEMVIDNVKVDDKVCEII
                     SEIMDESYTDIQILTHKLYSKGDDIKASKTIWMKKSGKEYSEAFAGTGEARIILLVND
                     IVNAQSNSLILIDEPEISLHPSAIYKFKEFLLQECLNKKHQIIITTHSTQLIKDFPRE
                     AVKLLVKNGEKVDVIENIDYQDAFFELGDVYHSRKMIYVEDRLAKYILEFVITHSGSE
                     NLKQNLVVRYIPGGANQIICNNILNSSYLDSDNHYFWLDGDQNTNVSESNNLMNYLEN
                     GVVISDKIPESDNKNLDDIIKLITGCPIKFNVSGNKGQKNNIELIAKQRSFIDYWAKY
                     VSYLPFPTP"
     gene            20990..21793
                     /locus_tag="VYO11_001140"
     CDS             20990..21793
                     /locus_tag="VYO11_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic/DOC family protein"
                     /protein_id="HEV1595722.1"
                     /translation="MQSTYNIDNPNLSYEAKRDLWRIGFGLQKVDNLVPSAYMESLAE
                     KQSRGELTYEQVYEDATAYHHTIDASTEEADLVSLRIVELLSRRGFSFSPATLLAIHK
                     ELFQDIFEPSIPVGQFRQTNITKNEPVLNGESVVYSDYSMIQMTLDYDFNQEKQVAYA
                     TLTQADVVKQIQHFISGIWQIHPFREGNTRTVTVFLIQYLREFGFDIDNTPFQQHSKY
                     FRDALVLDNAKILQRRSEFLTAFFENLLLGGQNDLSSEKMYLDLDLDFS"
     gene            complement(21909..23180)
                     /locus_tag="VYO11_001141"
                     /pseudo
     CDS             complement(21909..23180)
                     /locus_tag="VYO11_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            23240..23422
                     /locus_tag="VYO11_001142"
     CDS             23240..23422
                     /locus_tag="VYO11_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000842022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HEV1595723.1"
                     /translation="MKSQKIKVSFTQSKIVTPILLVNKTIVWYGAMPLLGKVDEMTIL
                     RLESASIASELVAGLR"
     gene            23722..24561
                     /locus_tag="VYO11_001143"
     CDS             23722..24561
                     /locus_tag="VYO11_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HEV1595724.1"
                     /translation="MIIKRILNHNAVIAQSKKDIDILLFGRGIAFGRKTGDKVNPIDI
                     EKSFFLKNRDNMTRFTEMFINVPLELVYITEKIINLGKITLGNNFDEIIYINLTDHIS
                     SSIERYKEGVIISNPLRWEISKYYKEEFELGKRALQIIKKELGIELPIDEAAFIALHF
                     VNANLENNFQESYKITEIIMGIEKIIQDFYCTEFNQDSIDYYRFITHIKLFAHRLVEN
                     TTYCDDDDEDLLALMKNKYPREYECGEQVAMFIQTEYNYLLTSSELVYLMAHIRRLTK
                     NLD"
     gene            24579..26417
                     /locus_tag="VYO11_001144"
     CDS             24579..26417
                     /locus_tag="VYO11_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEV1595725.1"
                     /translation="MSYKDTVQKILDVIGGEKNVNRVTHCVTRLRLELKDENLVNDDD
                     VKKIPGVIGIMKKNGQYQIILGNDVANYYKEFVKLGNFESDSVVQGHKGNILERIIEY
                     IAGSMTPIIPAMLGGGMLKVLVIILPMLGILQSDSQTIAFLTFFGDAPYYFLPLLLAY
                     SASQKLKVTSTLAMSVAGVLLHPNFVQMVQSGNPLSLFGAPVTPASYGSSVVPILIMV
                     WLMKYIEKIIAKLTPAITKSFLQPTLVLLVSSCIALVVVGPIGVIVGEGLSNLVGQMY
                     GVAGWLTLAILGAIMPFIVMTGMHWAFAPIFLAASIATPDVLILPAMLGSNLAQGAAS
                     MAVALKSKNNNTKQIAFAAGFSALLAGITEPALYGVTLKYKKPLYAAMIGGGLAGLFA
                     GLTSVKAYLFAVPSLIALPQFIYSDVPSNIVNALIVAVISVVITFVLAYIFGIDEEES
                     SSNLEVEAGVSNKKMIFSPISGEIIPLSDVQDKTFSDKLIGDGVAIIPSEGKVYAPFD
                     GKITNIFPTKHAIGLKSDEGVELLIHIGLDTVELKGQGFISHVEEGDRVFKNQLIFEM
                     DLNLIKTKGYETVTPVIVTNTNDFLDVLVLPNNQTIEHSKELLVIL"
     gene            26430..27845
                     /locus_tag="VYO11_001145"
     CDS             26430..27845
                     /locus_tag="VYO11_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEV1595726.1"
                     /translation="MTIFPDDFLWGGAVAANQVEGAYNEDGKGLSVQDVLPKGGLGEA
                     TENPTEDNLKLLGIDFYHKYKEDISLFSEMGFNVFRTSIAWSRIFPKGDEEEPNEAGL
                     KYYDELFDELHAHGIEPLVTLSHYETPLYLARKYHGWIDRRMIHFYEKFARTVLERYK
                     DKVKYWLTFNEVNSVLELPFTSGGIDIPKENLSKQELYQAIHHELVASSLVTKIAREI
                     NSEFKVGCMVLAMPAYPMTPNPKDVWATHEYENLNYLFSDVHVRGYYPNYAKRYFKEH
                     DINIEFAAEDAELLKNYTVDFLSFSYYMSVTQSALPTQYNSGEGNIIGGLVNPYLESS
                     EWGWQIDPIGLRIILNRYYDRYQIPLFIVENGLGAKDQLIKDEFNNLTVQDDYRIQYM
                     EEHLLQVAEALQDGVEIMGYTSWGCIDCVSMSTAQLSKRYGLIYVDRNDDGNGTFNRY
                     KKMSFTWYKGVIESNGESLFK"
BASE COUNT         8689 a         4825 c         5990 g         8426 t
ORIGIN      
        1 ctacattatg ttaaaaatcg ctcttgattg ataagttgga tttgttagga aaggagtaaa
       61 taattatgga taagaaaaag atagtttcga ctataatatg tatagtattt cttgtagtgt
      121 cagtagataa tttttttaga gacttaaccc cgttactgtt cattttaaat attattggcc
      181 tgtcttgctt ttcagtgcta acatacatta acataaaaga gatactctta aatataagta
      241 aatgatgatt tggttagtcc tagaaccaat caacttatgt ttatcggctt ggcagatttt
      301 atgtttgtca tttgtttgta tagaggtatt tcagaaacag aattctatca acaactaatc
      361 gcttatatag gtgtattctc tgcttgttta tcacgcttct gctcatgtgg ggcttgaagt
      421 attataaaaa gtagctttct atccttttct gacaggatat ttgagtagaa ggctctatta
      481 aattgttagt gaaataaatg aatggaggta tttaatatga aatacagatt attttttgtt
      541 attttcttga gtagtgtgtt ggatattctt ttagggacat ttttacaaat ctctatcgta
      601 tctattgggt ggcttgttct ttacagtggt ttgtttgaag caggagtttt ccttcttgct
      661 aataaagggg tggcggtaaa aatcaaggaa gtagatattc gaaatcgctt taaatttatt
      721 tttggaaaaa ccttatggtt tcaaattctt ttgctcatct ttttgataat caaactttat
      781 cttggtttgg atgcgaggtt gattttattc tatggacata ttttcattgt ctttaatgcc
      841 ttaatgtatc tattatctag tagtcaggtt agccttaaaa aaaacaaact gtcttcttaa
      901 tcttacagca gtagagcctg acaaggtgag gtcatagtag ggaggatttc tatgaaaaag
      961 tatcaacttc tattcaaaat aagtgcagtc ttctcttact tatttttcgt atttggtctt
     1021 tctcagctga cgcttatcgt ccaaaactat tggcaatttt cttctcagat aggcaattta
     1081 ttctggattc aaaatatctt gagtttactt tttattggag tcatgattgt ggttcttgtt
     1141 aagacaggcc atggttatct cttccgcatt ccaagaaaaa aatggctttg gtattcgatt
     1201 ttgacagtat tagtggtagt gttacagatc tcttttaacg ttcagacagc taaacatgtt
     1261 cagtcaactg cggaaggttg ggctgtattg attggttata gtgggactaa ctttgcagag
     1321 ctaggtattt atatagccct gttctttctg gttccactga tggaagaatt gatttataga
     1381 ggattactgc aacatgcttt ctttaagcat tcgcgatttg gtcttgattt gcttcttcct
     1441 tctattttat ttgctctccc tcatttttca agcctgccta gtctgttaga tatcttcgtc
     1501 tttgcaacag ttggaatcat ctttgctggt ttgacccgct ataccaagag catttatcca
     1561 tcctatgcgg tgcatgtgat caataatatt gtagcgacct tcccgttttt gctcactttt
     1621 ctacataggg tcttggggta aaaaaacaaa aggcttgctt ttcagccata gaggaggtca
     1681 tcatgtataa acacttattt ttcctagatt ccaaaacttt agatcggttg acaccctata
     1741 ttctagtctt ggcttctgac accattgctt ttaatgtttt tgtgctaacc tttgtatctg
     1801 cggtggtttt taatttccta aattccatgc tagctttaat ggctatattc ataggggctg
     1861 gctatgtggt cggattttgg ttactaatac tcaatgaaaa tcaaagagca aactaggaaa
     1921 ctagccgcag gctgtacttg agtacggcaa ggcgacgttg acgtggtttg aatttgattt
     1981 tcgaagagta taaaatggtt tgttttggaa aggctagaac taaagaatga cgtgtaggaa
     2041 gtctgtttgt tgaggaggat aattttatgg agttttttga taaatttcat gccttgtgtt
     2101 ttggattttt agtactaata attgtcatta cagttcctta tacgattaac catgggggtt
     2161 tttttcaaaa tgaatctgca ttgattcttg taagtcttct tgtaacctcg ctgagtgttg
     2221 cttatgctag aaagtttgaa atgatttctt ttgggatgtt aagcaagaaa caacttttgc
     2281 ttttcattgc aatctttctt ctaagtgtac ttgagacgct ggtttatatt catttcttcg
     2341 ctgtttcttc tggctcaggg gtccaacact tggcggaagt cagcagagga atttccctgt
     2401 ctttgatttt aactacctca gtttttggcc ccatccagga ggaactcatt ttcagaggac
     2461 ttcttcaagg tgcggttttt gacaattctt ggttagggct tgtgctaact tcctctctct
     2521 tttctttcat gcatggacct tctaatgtcc cttcgtttat tttttatcta cttgggggtt
     2581 tgttgctggg ctttgcttat aaaaagagtc aaaacctatg ggtttctact ctagtccata
     2641 tgctttacaa cagttggcca ctcttatatt atttataaaa attatgaaaa ggtaagcaga
     2701 agacggtgct tacctttttc aagctataat gatacccaag ccaatccaga ggcttttctt
     2761 tgagaatcgg gttagagtgg ttgacgaata ggccaaaaac tagtagaatg gtaaggaaac
     2821 tttatacgga ggaaagaaat ggatttgggt gataatgagc taacactgac tcccatacct
     2881 gggaaaagtg gcaaggctta tatgggtagc tatcctgatg ggaagcgcat ctttgtaaaa
     2941 atgaacacct ctccaatcct acctggtcta gctagagaac aaattgctcc acaattatta
     3001 tggagtcgtc gtttggcaga tgggcgtgat atgtgtgctc aagaatggtt gacaggcaag
     3061 atattgaccc cctatgatat gaatcgtaag caaatcgtca atattttaac ccgtcttcat
     3121 cgctcacgtc cgttgatgac acaattgagt cgtttgggct atgccatgga aacacctgta
     3181 gatttactac agtcttggca ggaaacggct ccagatgctt tgcgtaaaaa tcattttatc
     3241 agtgaagtga tggctgattt acgtcagact attccaggat ttagagagga ccatgcgacc
     3301 attgtccatg gagatgtacg acatagtaat tggattgaga cagatagtgg cttgatttat
     3361 ttagtagatt gggattcggt tcgcttgacc gatcgcatgt ttgatgtggc ccatatgctc
     3421 tgccattata tttcagaaca tcagtggaag gaatggttga cctactacgg ttacaagtac
     3481 aatcaaacgg tattaagtaa attgtattgg tatggtcaat tgtcttattt gagtcagatt
     3541 tccaagtatt atatgaacca agatttagaa aatgtcaatc gggagattca tggtttgcgt
     3601 catttccgag acaagtatgg aaagagaaga tgagagttag aaatcgtaaa ggggcaacag
     3661 aattactaga ggcaaatccc cagtatgtgg tcctcaatcc cttggaagcc aaggcaaaat
     3721 ggcgggactt gtttggcaat gataatccca ttcatgtgga agttggaagt ggaaagggtg
     3781 cctttgtttc aggtatggcc aagcaaaacc ctgacatcaa ctatatcggg attgatattc
     3841 aaaagtctgt tttgagctac gctttggaca aggtgcttga agctggagtg tctaacatca
     3901 agctcttgtg ggtagatggt tctgacttga ctgactactt tgaagacggt gagattgatc
     3961 gcttgtatct gaacttttca gatccatggc cgaaaaaacg ccatgaaaag cgtcgtttga
     4021 cctacaagac ctttttggat accttcaaac gtatcttgcc tgaaaatgga gaaattcatt
     4081 tcaagacgga taaccgtggc ttgtttgagt acagtttagt gagcttttct caatatggca
     4141 tgaaactcaa tggtgtctgg ctagatttgc atgccagtga ttttgaaggc aatgtcatga
     4201 cagaatacga gcaaaaattc tcaaacaagg ggcaagttat ctaccgagtt gaggcagaat
     4261 tttaagagat agcctaaaat taggctgtac aagtgctttt gctttacata agttggcaaa
     4321 cgtgctatac taagggtaag aatatgagaa agagaggcgg ggaaatatct tcgcctcttg
     4381 cttatgagga ggtggacgca atcgcaacaa tcgtagaatt agtcagagaa gttgtagaac
     4441 ctgtcataga agctcctttt gaactcgtgg atatcgagta tggaaagatt ggcagtgaca
     4501 tgattctcag tatttttgta gataaatccg aaggaattac cttgaacgac acggcagact
     4561 tgacagaaat gatcagtcct gtcctagaca ccatcaagcc agatcccttc ccagaacaat
     4621 atttcctaga aattaccagt ccaggtttgg aacgcccttt gaaaaccaag gatgccgtcg
     4681 ctggagcggt tggaaaatac atccatgtcg ggctctacca agccatcgat aagcaaaagg
     4741 tctttgaagg aaccttgttg gccttcgaag aggacgagtt gactatggaa tatatggaca
     4801 agacgcgtaa gaaaaccgtc caaattccat acagtttagt atcaaaagca cgtttagcag
     4861 ttaaattata gaaaaagaaa ggatagcttt tgaggattca aaagtgaaga aaacatgagt
     4921 aaagaaatgc tagaggcctt ccgcattttg gaagaagaca agggaatcaa aaaagaagac
     4981 atcatcgacg cagtagtaga gtcgcttcgt tccgcttatc gcagacgcta tggtcagtca
     5041 gacagcgtag ctattgactt caacgaaaaa acaggtgact ttacagttta tactgtccgt
     5101 gaagttgttg atgaagtatt tgatagccgt ttggaaatca gcttgaaaga tgctcttgcc
     5161 attaattcag cttatgaact tggagacaaa atcaagtttg aagaagcacc agctgagttt
     5221 ggtcgtgtag cagcccaatc tgccaaacaa accatcatgg aaaaaatgcg caagcaaaca
     5281 cgtgccatca cttacaatac ttacaaagaa catgagcaag aaatcatgtc tggtacagta
     5341 gaacgctttg acaaccgctt tatctatgtc aaccttggta gcatcgaagc ccaattgtca
     5401 aaacaagacc aaattcctgg agaagttttt gcttctcatg atcgtatcga agtttatgtt
     5461 tacaaggttg aagacaaccc tcgtggtgtg aacgtctttg ttagccgtag ccatccagaa
     5521 atgatcaaac gtttgatgga gcaagaaatt ccagaagttt atgatggaac tgttgaaatc
     5581 atgagcgtgg ctcgtgaagc aggtgaccgt acgaaggttg ctgttcgtag ccacaatcca
     5641 aacgtggatg ctatcggtac aatcgttgga cgtggtggtg ctaatatcaa gaagattact
     5701 agcaaattcc acccagctcg ttacgatgct aaaaatgatc gcatggtacc aatcgaagaa
     5761 aatatcgatg ttatcgagtg ggtagcagat ccagctgaat ttatctacaa tgccatcgct
     5821 cctgctgagg ttgaccaagt tatctttgat gaaaacgaca gcaaacgtgc cttggtggtt
     5881 gttccagata acaagctttc tcttgccatt ggtcgtcgtg gacaaaacgt gcgcttggcg
     5941 gctcacttga ctggttaccg tatcgatatc aagtctgcta gcgaatttga agccatggaa
     6001 gacgctgctt cagtagagtt ggaagtagaa aacgatactg tagaagaata aaagctgcta
     6061 gaggagggaa agatgaaaac aagaaaaatc cctttgcgca agtctgttgt gtctaacgaa
     6121 gtgattgata agcgtgattt gctccgcatt gtcaagaaca aggaaggaca agtctttatt
     6181 gatcctacgg gcaaggccaa tggccgcggc gcttatatca aactagacaa tgcagaagcc
     6241 ctagaggcga aaaagaagaa ggtctttaac cgcagtttta gcatggaagt ggaagaaagc
     6301 ttttatgacg agttgatcgc ttatgtggat cacaaagtga aaagaagaga gttgggactt
     6361 gaataagcaa aagataagta atctcttggg gcttgctcag cgagcagggc gcatcatatc
     6421 gggtgaagaa ttggtggtca aggccattca agacggcaag gccaagttgg tctttctagc
     6481 tcatgatgct ggacccaatc tgaccaagaa gattcaagat aaaagtcatt attatcaagt
     6541 agaaattgta accgtgtttt caacactgga attaagcata gcagtcggga aatcgagaaa
     6601 ggttttggct gtaacagatg ctggatttac aaagaaaatg aggtctctta tggaatagaa
     6661 gaggaggaca tgatttgtct aagaaaagat tgtacgaaat cgcaaaagaa cttggaaaag
     6721 aaagtaaaga agttgtagcg cgtgcaaaag agttgggctt ggatgtgaaa agccactcat
     6781 caagtgtgga agaagctgtc gctgcaaaaa ttgctgccag ctttaagcct gcagctgctc
     6841 cgaaagtaga agcaaaacct gcagcaccaa aagtaagtgc agaaaagaaa gccgaaaaat
     6901 ctgagccagc taaaccagct gtagctaagg aagaggcaaa accggctgag ccagttgctc
     6961 cgaaaacaga aaaagtagca gcgaaaccgc aaagccgtaa tttcaaggct gagcgtgaag
     7021 cccgtgctaa agagcaggca gaacgacgca agcaaaataa gggcaataac cgtgaccaac
     7081 aacaaaacgg aaaccgtcag aaaaacgacg gccgtaatgg tggaaaacaa ggtcaaagca
     7141 accgcgacaa tcgtcgcttt aatgaccaag ctaagaagca gcaaggtcag caaaaacgta
     7201 gaaatgagcg ccgtcagcaa gaggacaaac gttcaaatca agtggctcca cgtattgact
     7261 ttaaagcccg tgcagcagcc ctaaaagcag agcaaaatgc agagtacgct cgttcaagtg
     7321 aggaacgctt caagcagtat caggctgcta aagaagcctt ggctcaagct aacaaacgca
     7381 aggaaccaga ggaaatcttt gaagaagcgg ctaagttagc tgaacaagca cagcaagttc
     7441 aagcagtggt tgaagtcgtc cctgagaaaa aagaacctgc agtggataca cgtcgtaaaa
     7501 aacaagctcg accagacaaa aatcgtgacg attatgatca tgaagaagat ggtcctagaa
     7561 aacaacaaaa gaatcgaagt agtcaaaatc aagtgagaaa tcaaaagaat agtaactgga
     7621 ataacaacaa aaagaacaaa aaaggcaata acaagaacaa ccgtaatcag actccaaaac
     7681 ctgttacgga gcgtaaattc catgaattgc caacagaatt tgaatataca gatggtatga
     7741 ccgttgcgga aatcgcaaaa cgtatcaaac gtgaaccagc tgaaatcgtt aagaaacttt
     7801 tcatgatggg tgtcatggcc acacaaaacc aatccttgga tggggaaaca attgaactcc
     7861 tcatggtgga ttacggtatc gaagccaaac aaaaggttga agtggataat gctgacatcg
     7921 aacgtttctt tgtcgaagat ggttatctca atgaagatga attggttgag cgtccaccag
     7981 ttgttactat catgggacac gttgaccacg gtaaaacaac ccttttggat actcttcgta
     8041 actcacgtgt tgcgacaggt gaagcaggtg gtattactca gcatatcggt gcctaccaaa
     8101 tcgtggaaaa tggtaagaag attaccttcc ttgatacacc aggacacgcg gcctttacat
     8161 caatgcgtgc gcgtggtgct tctgttaccg atattacgat cttggtcgta gcggcagatg
     8221 acggggttat gcctcagact attgaagcca tcaaccactc aaaagcagct aacgttccaa
     8281 tcatcgtagc cattaacaag attgataaac caggtgctaa cccagaacgc gttatcggtg
     8341 aattggcaga gcatggtgtg atgtcaaccg cttggggtgg agattctgaa tttgttgaaa
     8401 tctcagctaa attcaaccaa aatatcgaag aattgttgga aacagtcctt cttgtagctg
     8461 aaatccaaga actcaaggca gacccaacag tgcgtgcaat cggtacggtt atcgaagcgc
     8521 gcttggataa aggaaaaggt gcggtcgcaa cccttcttgt acaacaaggt accttgaatg
     8581 ttcaagaccc aatcgttgtc ggaaatacct tcggtcgtgt ccgtgctatg accaacgacc
     8641 ttggtcgtcg tgttaaagtt gctggaccat caacaccagt ctctatcaca ggtttgaacg
     8701 aagcaccgat ggcgggtgac cactttgccg tttacgagga tgaaaaatct gcgcgtgcag
     8761 caggtgaaga gcgtgccaaa cgtgccctca tgaaacaacg tcaagctacc caacgtgtta
     8821 gccttgaaaa cctctttgat acccttaaag ctggggaact caaatctgtt aatgttatca
     8881 tcaaggctga tgtacaaggt tctgttgaag ccctttctgc ctcacttcaa aagattgacg
     8941 tggaaggtgt caaagtgact atcgtccact cagcggtcgg tgctatcaac gaatcagacg
     9001 tgacccttgc cgaagcttca aatgccttta tcgttggttt caacgtacgc cctacaccac
     9061 aagctcgtca acaagcagaa gctgacgatg tggaaatccg tcttcacagc attatctaca
     9121 aggttatcga agagatggaa gaagctatga aagggatgct tgatccagaa tttgaagaaa
     9181 aagttattgg tgaagcggtt atccgtgaaa ccttcaaggt gtctaaagtg ggaactatcg
     9241 gtggatttat ggttatcaac ggtaaggttg cccgtgactc taaagtccgt gttatccgtg
     9301 atggtgtcgt tatctatgat ggtgaactcg caagcttgaa acactataaa gacgacgtta
     9361 aggaagttac aaacggccgt gaaggtggat tgatgatcga ctgctacaat gatattaaga
     9421 tggatgatgt gattgaggcg tatgtcatgg aagaaatcaa gagataagat tttttgctcc
     9481 tttcttaggt ggtgagggac gcaagcaaac cgatggtttc attgcttatt tttgagccta
     9541 gggtctcaaa aatcccctgt gatgggactg ataaatcagt tccatcactt tcaccacggc
     9601 gaaagaagca gatgacttca aattgaactt cgtttcaatt taaactgaaa atcaagaagt
     9661 ttaaaatagc taggtctgct ggcctagctt ttggttcaaa gtagagaaag gaatatcatg
     9721 gcaaatcatt tccgtacaga tcgtgtgggc atggaaatca agcgtgaagt caatgagatt
     9781 ttgcaaaaga aagtccgtga tccacgtgtc caaggtgtga ccatcacaga tgttcagatg
     9841 ctgggtgact tgtctgttgc caaggtttat tacaccattt tgagtaacct tgcttcggat
     9901 aaccaaaaag cccaaatcgg gcttgaaaaa gcaactggta ccatcaaacg tgaacttggt
     9961 cgcaatttga aattgtacaa aatcccagat ttgaccttcg tcaaagacga gtccatcgag
    10021 tatggaaaca agattgacga gatgctacgc aatctggata agaactaaag aagaggggtt
    10081 gcccctcttt tttggtggag gaaaataggt tgaatttgaa atggaaaaat attcttttat
    10141 aatagtttga aactagaata gtacgcctct acttctaaaa tattgttaga aatcgatttg
    10201 actgtcctga tcgatttgtc ctgttcttgt ttcattttac tataaaaaag gggttctgta
    10261 ttttttaatg ttatctaatt agaaaatgct ttttttgtag gaaatataat atgataaggt
    10321 gcaaaaaaga aataaggagt ttgtatatgg ctgaacaaga cttagctatg caagtattgc
    10381 aacaagtggt gaaactacct gttgttaagg ttgatcgttc gaaattttta gtggataagt
    10441 tttccaaaga attgggtcca caggacattc ctaccttatt ggaacaaggt ccaacgtctc
    10501 tcttatctca agaaatctta gatcgagtgg ctaatgcctg tattagggat aatgttttat
    10561 tagcgagtgg gacttctgtt ttggcaggat tacctggagg gcttgctatg gcaattacca
    10621 ttccagctga tgtggctcaa ttttatggtt tctctctgaa attggcccaa gaattaggtt
    10681 atatttatgg ttatgaggat ctttgggctt cacgcgatga gttgagtgaa gatgctcaaa
    10741 ataccctttt gctttatcta ggcgtcatgt tgggggtgaa tggaactgct gctttgctac
    10801 gtgctggtgg tataacaatt gccaaacagg taatgaaaac agtacctaat aaagctttaa
    10861 caaagacgct ttggtatcct attttgaaga aagtcttaag aatatttggt gtgaatctta
    10921 ccaagggagg gctggccaaa ggaatgggga aatttattcc tatcttgggt ggtatcattt
    10981 caggtggttt aacctttgca actatgaaac caatggggga aagcttgcag aaagaattat
    11041 ccaagctagt caactatagt gaagttcaat atcaagaaga tgttgaaaca atccgaaaag
    11101 aggctgaaat catcaaagga gagtaatatg aatcctatca aagcttttgc taaaatttat
    11161 ggtaattact ttttgaccgt gcaaggtgta aaagtaatga aaacgataaa gaaagatgat
    11221 aatgccgttg tcggtctggg gaaacttttt attgccgaca agttaatgga tacggctcgg
    11281 tggctcatta agccagagga taaaaaatga aatttttctg gggacttctt gccattattt
    11341 ttatcaaacc gattattggg attgtgaaat tcttttggat gatcatctct tttgcagtcc
    11401 aattgctgtt ttacaagata ttggattggt tctttaaact tatctagatg gtaatccaag
    11461 tcgcagagaa ctagcaggaa ctccactgct agttttttat tctctttcca tatggtataa
    11521 tataagcagt aaaatcattt tatactcttc gaaaatctct tcaaaccacg tcagcttcac
    11581 cttgctgtat atatgttact gacttcgtca gttctatccg caacctcaaa acggtgtttt
    11641 gagctgactt cgtcagttct atctacaatc tcaaagcact gttttgagca acctgcggct
    11701 agcttcctag tttgctcttt gattttcatt gagtattaga acatataatg gaggtcgtca
    11761 tggacaatat catcgatgtg tcaattcctg ttgcagaagt ggtggacaag catccagaag
    11821 tcttggaaat tctagtggag ttgggtttta aaccccttgc caatccctta atgcgcaata
    11881 cagttggtcg taaagtatca cttaaacagg gttctaagct agcaggaact cctatggaca
    11941 agattgtacg cacactggaa gcgaatggct acgaagtgat tggattagac taatggcaga
    12001 tgaacggatt catgtcctac gggatatttt attagaattg cataatggcg cctctcctga
    12061 gtcggttcag gagcgttttg atgcgacctt tgcgggtgtc tcagccattg agatttccct
    12121 tatggagcac gagctgatga actcggattc gggcgtcact tttgaagatg ttatggaact
    12181 ctgtgatgtc catgccaatc tttttaaaaa tgctatcaaa ggtgtcgaag tttcagatac
    12241 tgagcatcca ggtcacccag ttcgtgtctt caaagaagaa aatctggctc tccgtgcggc
    12301 cttgattcgc attcgtagat tgttagatac ctatgagtct atggaagacg aggaaatgct
    12361 ggcggagatg cgtaagggtt tggtgcgtca gatgggactt gtgggtcaat ttgacatcca
    12421 ttaccaacgt aaggaagaac tcttctttcc tatcatggag cgctatggac acgattcacc
    12481 tcccaaagtt atgtggggag tggatgatca gattagggaa ctctttcaaa cagctctaac
    12541 gacagccaag tcactaccag aagtgtcaat tagcagtgta aaggaagctt ttgaagcttt
    12601 tgcgacagag tttgaaagta tgattttcaa ggaagagtcc atcctgctca tgattctcct
    12661 tgagtctttt actcaggatg actggcttca gattgcggag gagagtgatg cctatggcta
    12721 tgccatcatc cgtccgtcag agaaatgggt gccagaacga cagatcttta ttgaggaaaa
    12781 gattgcagag gagcctgtac aactagatac ggcagaaggt caagttcaac aagtcataga
    12841 tacgccagaa ggccatttta ccattacctt tacccctaag gaaaaggaag ctgtgctgga
    12901 ccgccatagt caacaggctt ttggtaatgg ctatctttca gtcgagcagg ccaatctcat
    12961 cctcaatcat ctccctatgg agattacctt tgtcaataaa gaagatattt tccagtatta
    13021 caatgacaat acgccagctg atgagatgat tttcaaacgg acgccgtccc aagtcgggcg
    13081 caatgtcgaa ctctgtcatc cgcctaagta tttggacaag gtcaaggcta tcatgaaggg
    13141 acttcgtgag gggaccaagg acaagtatga aatgtggttc aagtctgagt cgcgaggtaa
    13201 gtttgtccac atcacctatg ctgcagtaca cgatgaagac ggagaattcc aaggagtgtt
    13261 ggagtatgtt caggatatcc agccctaccg tgagattgat acggactatt ttcgtggatt
    13321 agaataagga gaaaaaatga gttacgaaca agaatttatg aaggaatttg aagcttgggt
    13381 caatacccaa atcatgatta acgatatggc gcacaaggaa agtcaaaaag tttacgaaga
    13441 agaccaggac gagcgtgcca aagatgccat gattcgctac gagagtcgct tggatgctta
    13501 tcagttcttg cttggtaagt ttgaaaactt caaagtaggc aagggattcc atgatttgcc
    13561 agaaggcttg tttggtgagc gaaattatta aacgagaaag attcttgatt tttcactaaa
    13621 atcttgatag aatgtttatg ttaaatcctt gtcagagcag ggatttttta ttgaaaggat
    13681 tttatcatgt caaagaaact caatcgtaaa aaacaattac gaaatggcct ccgtcgcgca
    13741 ggtgcctttt caagtactgt gactaaggtt gtagatgaga caaaaaaagt cgtgaagcgt
    13801 gcagaacagt cagcaagcgc agctggtaag gctgtttcta aaaaagttga acaagcagta
    13861 gaagctacca aagagcaagc tcaaaaagta gctaattctg tagaagattt tgcagcaaat
    13921 ttgggtggac ttccacttga tcgtgccaag actttctatg atgaaggaat caagtctgct
    13981 tcacatttca aaaactggac tgaaaaagaa ctccttgact tgaaaggaat cggcccagct
    14041 accatcaaga aattgaaaga aaatggcatc aagttcaagt aatttttctt gagccttgca
    14101 tttccgaaaa aatcttgcta caatagagcc attagaggtg ttttgaatcc cacattttac
    14161 agaaagtggc ggcgctgaga agtccacaaa tgtgtcaaaa ctggttgcta atggatgaaa
    14221 aattgaaata tttctgtctt tttattttaa agactaaaga tgcgggcttg gcccgaaatt
    14281 gggtggtacc gcggataaac acattcgtcc ctgtcatgta gatggcaggg cttttctttt
    14341 acgtcttagt caaagggggt tgttatgaag caatctttta acacaagtaa actatattat
    14401 ggttttcctg tttttatttt aggatatcaa gattagaatt ttggctataa catcacgacc
    14461 tgtagttcct cttatagtct aggagattgg gttgtgattg gagtcgttgc gagagagaat
    14521 gccgcagagc agatcaaaca gtatcaaaaa tttactgtga atatttctga tgaaacttct
    14581 atgcttgcga tggagcaggc tggttttatc agtcatcagg agaaattgga acgtttggga
    14641 gtgcattatg aaatttctga acgaactcag actcctattt tagacgcctg tccacttgtt
    14701 ttagattgtc gggtagatag gattgttgag gaagacggta tttgccacat ctttgccaag
    14761 attcttgagc gacttgttgt tccagaactc ctggatgaaa agggacattt taaaaatcaa
    14821 ctgtttgccc caacctattt catgggagat ggatatcagc gcgtttatcg ctatctggac
    14881 aagcgtgtag atatgaaggg cagtttcatc aaaaaagcga ggaagaagga tggcaagaac
    14941 tgagctacca gataaaatcg aaacagaatg tctcgtttta cgagtccgta ctgtggcgga
    15001 tgctgaggat atctttgact atgctagttt gccagaggtc gcctatccag caggttttcc
    15061 tccagtcaag accttggaag atgagattta ttatctggag cacattcttc cggagcgtaa
    15121 tcaaaaggaa aatctcccag caggctacgg gattgtcgtc aaaggaacgg ataagatcgt
    15181 tggctctgtc gatttcaacc atcgccatga agatgatgtg ctggaaatcg gctatacctt
    15241 acacccagac tattgggggc gaggttatgt gccagaagct gcgcgtgcct tgattgactt
    15301 agcctttaaa gatttgggtc ttcacaagat tgaactaact tgctttggat ataaccttca
    15361 aagtcaacga gtcgcggaaa aacttggctt taccctcgaa gctcgcataa gagaccgcaa
    15421 agatgctcaa ggcaactgct gtgatgattt gagatatgcc tttctgaaga gtgagtggga
    15481 ggtgatttga tgcatctttt catcattggt gctccagcat caggaaaaat gaccattggt
    15541 caagaattat ctcgactgac ggatgctacc ctcttttata accatcaagc cattgatttt
    15601 gcactagaaa tctatcagga ctatacagag gaaatgtggg aatttgttcg tggaatcact
    15661 ttttcattcc ttggagcgag tgcaagaaat cagcgatcag taattttaac agatgtaatt
    15721 gatttttcaa atcagtatca tctgatatat ttaaagcaaa ttcagagttt gttggatgat
    15781 tatcatcaag agattctttt tgttgagttg gaaacaagtc ttgaagagtg catacgtcga
    15841 aatcgaacgg agaatcgatt aaagtacaaa cccttaaaac gacatattga ggtatctgaa
    15901 agagaaatta tagagaccgc tgaaacactt caattaaatt cccaacatca accgaatgag
    15961 ttgaaccact actttaaaat aaataatacg aatttgtctg cagaagaagc tgctaagcaa
    16021 attcaaaata aaataaacaa aatagagaaa ggacacacac atgtctaaag aactttcacc
    16081 taaatacaat ccagccgagg ttgaggctgg tcgttatcaa aaatggcttg atgctgatgt
    16141 tttcaagcct tcaggcgatc aaaaggctaa gccttattca atcgttattc caccaccaaa
    16201 cgttacaggt aaacttcacc ttggtcacgc ttgggataca actttgcaag atattatcat
    16261 ccgtcaaaaa cgcatgcaag gttttgatac cctttggctt ccaggaatgg accacgctgg
    16321 tattgcgact caggctaagg ttgaggagcg cttgcgtggt gagggcattt cccgctatga
    16381 ccttggtcgt gagtctttct tgacgaaagt ctgggaatgg aaagacgaat atgccactac
    16441 catcaaggaa caatggggca agatggggct ctctgtagac tattctcgtg agcgtttcac
    16501 tcttgacgaa ggtttgtcaa aagctgttcg taaggtcttt gtggaccttt acaagaaagg
    16561 ctggatctac cgtggtgagt ttatcatcaa ctgggaccca gcagctcgca cagccctttc
    16621 tgatattgag gtgattcaca aggatgtgga aggtgccttc taccacatga attacatgct
    16681 ggaagatggt tcacgcgccc ttgaagttgc tacaactcgt cctgagacta tgtttgggga
    16741 cgttgcggtt gcggttaatc cagaagaccc gcgctacaag gacttgattg gtaaaaacgt
    16801 catccttcca atcgctaata aactcatccc aatcgttgga gatgagcacg cagatcctga
    16861 gtttggtact ggtgtcgtga aaatcacacc tgcccacgat ccaaatgact tcttggttgg
    16921 ccaacgtcat aacttgccac aagtcaacgt catgaacgac gacggaacta tgaatgagct
    16981 tgcctttgaa ttttcaggca tggatcgttt tgaagctcgt aaggcagtcg ttgctaagtt
    17041 ggaagaaatc ggtgcccttg tcaaaatcga aaaacgtgtc cattcagtcg gtcactcaga
    17101 acggacaggt gtcgtagttg agccacgctt gtctactcaa tggttcgtca agatggacca
    17161 attggctaag aacgccattg ccaaccaaga cacagaggac aaggtcgaat tctacccacc
    17221 tcgtttcaac gataccttcc ttcaatggat ggaaaatgtc cacgactggg ttatctctcg
    17281 tcagctttgg tggggtcacc aaatccctgc ctggtacaat gctgatggtg aaatgtatgt
    17341 cggcgaagaa gctccagaag gtgacggatg gactcaggac gaagacgtct tggatacttg
    17401 gttcagttct gccctctggc cattttcaac catgggctgg cctgaagtcg actcagaaga
    17461 ctttaaacgt tatttcccaa cttcaacctt ggtaacaggt tacgacatca tcttcttctg
    17521 ggtgtctcgt atgatcttcc agtcattgga attcacaggc cgtcaaccat tccaaaacgt
    17581 ccttatccac ggtcttattc gtgacgagca aggacgcaag atgtctaagt ctctcggtaa
    17641 cgggattgac ccaatggatg ttatcgagaa atacggtgcc gatgcccttc gatggttcct
    17701 ttcaaacggt tctgcgccag gacaagacgt gcgtttctct tatgagaaaa tggatgcttc
    17761 atggaacttc attaacaaga tctggaacat ctctcgctac atccttatga acaatgaagg
    17821 tttgacgctg gatgtggcgc atgacaatgt cacaaaagtt gcaacaggtg aggctggtaa
    17881 tgtgacggac cgctggattc tccacaatct caacgaaacc attgcaaaag ttactgaaaa
    17941 ctttgataag ttcgagtttg gtgtggctgg tcatatcctt tacaacttca tttgggaaga
    18001 atttgccaac tggtatgttg aattgaccaa ggaagtcctt tacagcgaca atgaagacga
    18061 taaggtcatt actcgatctg ttctccttta cactctggac aagatccttc gtctccttca
    18121 cccaatcatg ccattcgtga cagaggaaat ctttggacaa atctcagaag gttctatcgt
    18181 gacagctgca tacccaactg ttaatctagc ctttgaagac cttgcggctc atactggtgt
    18241 agaaagtctc aaagacttga tccgtgccgt tcgtaatgcg cgtgcggaag taaacgtagc
    18301 accaagcaag cctatcacca tccttgttaa gacaagcgat agcgacttgg aagccttctt
    18361 taacagcaat gtcaactata tcaaacgctt tacaaatcca gaacacttgg aaatcgcatc
    18421 aaccatccct gcacctgaac tggctatgtc aagcgtcatt acaggagcag aaatctacct
    18481 gccattggct gacctcctca atgtcgaaga agaactggct cgtcttgaca aggaacttgc
    18541 taaatggcaa aaagaactgg acatggtcgg taagaagctc tttaacgaac gcttcgtagc
    18601 caacgccaaa ccagaagtcg tccaaaaaga acgcgacaaa caagctgact accaagccaa
    18661 gtatgatgcg accgtagcac gtattgatga gatgaagaag ttggtgaaat gatgttaaaa
    18721 acctaaccct ctcgggttgg gttttacatt tgataatgtt ataataaaaa ggagaaactt
    18781 taggagaata ctatggggaa aattgttgct attgatttat ttagcggtgc aggtggcact
    18841 acaagtggcc ttaaaaaatc aggcatagat gttcaagttg ctgttgaaat tgattccgta
    18901 gctgttaaaa cttataagtt aaataatcct gaggtgtctg taatagatat ggagtaaata
    18961 aaacttcaat tttacaagct ttatatggtt ctccagccaa taaaagtgtg tctgaatatt
    19021 ggtttagtac aaatgttgat caaatagatg aagtggatgg gaaacaatgt ttaatctatt
    19081 catattataa cgttaaagct tctagaaatg tagaagttct taaaggccgt tctggaacaa
    19141 aaaaaggatt agattattgg gaaccatatg ctcctcaaaa acaatatgag atggaaagat
    19201 tacccaaaaa taaatatatt ggaagttctt cgacagacag atgggatggc attgaaaaaa
    19261 atgttgtctt ttgtgattgt aaagaatatg tttctgcttt tgatttattt ttctatcact
    19321 ataattttaa aaaaatttct actcaacgta gtaaacaaga ttttataaga ttacgatcta
    19381 aaccagttgc tgatatttta aagaataata caagtagcta tacgcgttat aaaaaggaaa
    19441 tggttataga taatgttaaa gttgatgata aagtttgtga aattattagt gaaataatgg
    19501 atgaatctta tacagacatt caaattttaa cacataagtt gtattcaaaa ggtgatgata
    19561 taaaagcttc caaaactatt tggatgaaaa aatctggaaa agaatattct gaggcttttg
    19621 caggaacagg tgaggctaga attattttgt tagtaaatga tatagtaaat gcgcaatcaa
    19681 attcattaat attaatagat gaacctgaaa tctcacttca tccgagtgca atctataaat
    19741 ttaaagagtt tttacttcaa gagtgtttaa ataaaaaaca tcaaattatt atcactacac
    19801 attctacaca acttataaaa gattttccta gagaagccgt gaaactttta gtgaaaaacg
    19861 gagaaaaggt agatgttatt gaaaatattg attatcagga tgcatttttt gaattaggtg
    19921 atgtgtatca ttctaggaag atgatttatg ttgaagatag actagctaaa tatattctag
    19981 agtttgttat cactcattca ggtagtgaga atcttaaaca gaatttagta gtgagatata
    20041 tccctggtgg agcaaatcaa ataatttgta ataatatttt aaactcatcg tatttagatt
    20101 ccgataacca ttatttttgg cttgatggag atcaaaacac taatgttagt gaatcaaata
    20161 atttaatgaa ctatcttgaa aatggtgttg ttatatcaga taaaattcct gaatcagata
    20221 ataaaaatct tgatgatatt ataaaattga taacgggatg tccaattaaa tttaatgttt
    20281 caggtaataa agggcaaaaa aataatattg aattaattgc gaaacaaaga agctttatag
    20341 attattgggc taaatacgtt tcttatcttc ctttcccaac cccatagttt tttttagcta
    20401 atttatgtaa cagcgtagat agggaaggtt atgatttttc taaagatggc aacggaaaag
    20461 aatattttag aaaaaaattc aagtagcgtt aggaatagag aatataactt ctgaagatat
    20521 tttccaggag caaagaagag ctgtttcaaa aatacagcca gaatcatcaa tgtttcagtg
    20581 tattaaagaa aaattagagg cattgttcta attccttaga ttaggtacta cataacaaat
    20641 ttttaaattc aaacccgcac caaaaacaac attgcaactt tcttctcagg taatgtgttg
    20701 ggatttgaac agatcaacga gttcatagtg gtgtatgcca atgactttga taagtctacg
    20761 cgtcagactt attagttcat ttatccagat atatctcgat aatcatatta tttagttaaa
    20821 gaacatccca tatgagggca tgaaatgcta agtttagctt gctcactatt aagatgaagt
    20881 atatatattt catagaacct attgtgaagg atttttataa ttttcgccaa ttccatacct
    20941 atttcacaat ttaccgatga cacagaaaaa caattgaaag gatatttcta tgcaatcaac
    21001 ttacaacatt gacaatccaa acttgtctta tgaagcgaag cgtgatttat ggcggatagg
    21061 ttttggtctg cagaaagttg acaatctagt gccatcagcg tatatggaat ctttggctga
    21121 gaaacagtcc cggggagaac tgacttatga gcaggtttat gaggatgcaa cggcttatca
    21181 ccatactatt gatgcaagta cggaagaggc agacttggtt tctctacgta ttgtagaact
    21241 attgtctcga agaggcttta gctttagtcc tgcgacctta cttgctattc ataaggagtt
    21301 gtttcaagat atatttgaac cctctattcc ggtggggcaa tttcgtcaga ccaatatcac
    21361 aaagaatgaa cctgttttga atggtgaaag tgttgtgtac tctgattact ccatgattca
    21421 aatgacctta gattatgatt ttaatcagga aaaacaagtt gcatatgcga cactaactca
    21481 ggcggatgtg gttaaacaaa tccagcattt tatttcagga atctggcaga ttcatccatt
    21541 tcgcgaagga aacactcgga cagtaacggt ctttttgatt cagtatcttc gtgagtttgg
    21601 ttttgatatt gataatacac catttcagca acattccaaa tattttcgtg atgccttggt
    21661 attagataat gcaaagattt tacagcgacg ttctgagttt ttaacagctt tttttgaaaa
    21721 tctcttgctc ggtggtcaaa atgatttgtc ttcagaaaaa atgtatctag atttagacct
    21781 cgatttttca taatccaaat actgagtaaa cattgaattt taggcaaaaa tgaagtaaat
    21841 attctcacaa gaaaacgtat atcatcaaag ttttaggtgt actgacccca aaaagttaga
    21901 caaataattt atccgaagga tttagttctg tattgcacaa ggctaagtcc ttttagtttt
    21961 accttaattc gtttattgtt gtagtaatca atatagtcta caatagcttg ttccaattga
    22021 ttaagtgatt taaatgtttt ctcatagcca taaaacattt ccgatttcag aatcccaaag
    22081 aaggactcca tcataccgtt gtcttggctg tttcccttac gtgacatgga tgcttgaatt
    22141 cccttaccct caagaaactg atgataagaa tcgtgttggt attgccagcc ttggtcacta
    22201 tggagaatcg tattctcgta gtgcttctct gtgaatgcct gttccaacat tgtttgtact
    22261 tgttctaaat taggcgaaca agaaagatta aaagcaataa tttcgctgtt aaagccatct
    22321 aaaactggtg ataagtaaag cttttgagta cttgctggaa tggcaaattc tgtcacatct
    22381 gtatagcact tttccattgt tttagagcct tcaaattggc cttgaatgag attctctgcc
    22441 ttcttgccaa cgtctccttt atgagaagaa tattttcgtt tctgtcgcat tttagcttgt
    22501 aaattgagta ctttcatcaa gccttgaact cttttatgat ttaccagata agcacgattt
    22561 cttagttcta aataaatccg acgataagca taatttccct tgtgttcgat aaaaatggat
    22621 tgaatttcag ctttaagctc ttggtcctta tctgttttgt ctagctgttt caagtgatag
    22681 tagtaggtcg aacgagctag tttaatggat tttagaagaa gaactaacga aaactcagtc
    22741 attaattctt gaacaatttc tgtctttctt ctttctcttt ttcctccttc aatcggagtt
    22801 ctcttaactt ttttaggatg gcattctccg ctctcaggta ctctcccttt tgttttctca
    22861 acaatagtat acccgttttt cctgtattgt gctagccagt taagaagtat cgtacgactt
    22921 gggaggccgt attcaagaga aactctatct ttagtccagc cttcatgtca gactttatga
    22981 atcatttctt gttttaaatc aggagaatag taacgatttt ttcctttttt gccgaactct
    23041 attccgtaac gatcaatcaa tttaatcatg tacctaagat tagaattgtt tatcccaaat
    23101 ttatttgaaa gcttctctaa gctatatcct tgttttctaa gttcatagat ctgaacttta
    23161 tcatcataag ttaatttcat aataaaaaca ccccaaaagt tagatttttt ctgtctaact
    23221 tttggggtgt agttcacagt tgaagagcca gaaaattaaa gtgtctttta ctcaatcaaa
    23281 aatagtaacg cctattcttt tggtgaataa gactattgtt tggtatggtg caatgccatt
    23341 attagggaag gtagatgaga tgaccatatt acgtttggaa tcagctagta tagcttctga
    23401 actagtggca ggtttacgat agagaaaatt tttaaaaatt tctatgtatg attttcattt
    23461 ctttagtgag actgttgtca ttatcacatt cgaatcacac aaaataaaaa aatttctata
    23521 agtacttgac aaatagattg aaatatctta aaatgaaaat ggttacagag ttattaatga
    23581 tttaagcttc atgtcaccat taaaaattga aataaaagga tgttatcact aatacaagtg
    23641 agcaggaacc tatttaatca catcggaaga agtttcttga tgtttttaag taggttcctt
    23701 ttattttaaa agggaaattt tatgatcata aaacgaatac taaaccacaa tgccgtaatt
    23761 gcgcaaagta aaaaagatat cgatattctt ctttttggaa ggggaatagc ttttggaaga
    23821 aaaactggag ataaagtaaa tccaattgat attgagaaaa gtttttttct caaaaataga
    23881 gataatatga cccgttttac agagatgttt attaacgttc ctttggagtt ggtgtacatc
    23941 accgaaaaaa taattaacct aggtaaaata acattgggta ataattttga tgaaattatc
    24001 tatattaatt taacggatca tatttcttcg agcatagaac gttataaaga aggagttatt
    24061 atttcgaatc ccctacgctg ggaaatctcg aaatattata aagaagaatt tgaacttggg
    24121 aaaagggctt tacaaataat aaaaaaagag ttaggtattg aacttccaat tgacgaagct
    24181 gcattcatag cgctacattt tgttaatgct aatttagaaa ataattttca agagtcgtat
    24241 aaaatcactg aaataattat gggaattgag aaaatcattc aagatttcta ttgtactgag
    24301 tttaaccaag attctattga ttattataga ttcataactc atataaaatt atttgcccat
    24361 cgcttggttg aaaatacaac ttattgtgac gatgatgatg aagacttgtt agcattaatg
    24421 aaaaataaat atcctagaga atatgaatgt ggtgaacagg tggcaatgtt tatacaaacg
    24481 gagtacaatt atttgctgac ttctagtgaa ttagtttatt tgatggctca tattcgtcgc
    24541 ttaacaaaaa atttagatta atagaatagg agaataccat gagttataaa gatacggtac
    24601 aaaaaatcct cgatgtaatt ggaggtgaaa aaaatgtcaa tagagttacc cattgtgtaa
    24661 cacgtttaag attagaatta aaagatgaaa atttagtcaa tgatgatgat gtgaagaaga
    24721 taccaggtgt aataggtatt atgaaaaaga atggacaata tcaaattata cttggtaatg
    24781 atgtagctaa ttattataaa gaattcgtta aacttggcaa ttttgaatcc gattcagttg
    24841 ttcaagggca caaagggaat attttagaaa gaatcattga gtatatcgct ggttccatga
    24901 ctccaatcat tccagcaatg ttagggggag gtatgttgaa agtcttggta atcattttac
    24961 caatgcttgg tatattgcaa tcagattctc agactattgc ttttttgaca ttttttgggg
    25021 atgctccata ttatttctta ccgctgttat tagcttattc tgcatcacaa aaattaaaag
    25081 taacatctac attagctatg tctgtagcag gtgtacttct ccatccaaat tttgttcaaa
    25141 tggtgcaatc agggaatcct cttagtttat ttggtgcacc tgtgacacca gctagttatg
    25201 gttcatcagt cgttccaatt cttattatgg tttggttgat gaaatatatt gaaaaaataa
    25261 ttgctaaatt aacaccagct attactaaga gttttttgca acctacgcta gtattattag
    25321 tatcaagctg tattgcctta gttgtagtcg gacctattgg agtaattgtt ggtgaaggat
    25381 tatcaaatct agttgggcaa atgtatggtg tagctggatg gcttacatta gctattcttg
    25441 gtgctattat gccatttatt gttatgactg gaatgcattg ggcttttgca cctatttttt
    25501 tggcggcatc tattgctact ccagacgtat taattcttcc agcaatgtta gggtcaaact
    25561 tagctcaagg ggctgcttcg atggctgttg cattaaagag taaaaataat aatacaaaac
    25621 aaattgcttt tgcagcaggt ttctcagcct tacttgcagg gattaccgaa cctgcattat
    25681 atggtgtgac tttaaaatat aaaaaaccgc tttatgcagc tatgattggt ggtggattag
    25741 cgggattatt tgcaggtctt actagtgtta aagcatatct atttgctgtc ccatctttga
    25801 tagcgttgcc tcaatttatt tattctgatg tgccatcaaa tattgtaaat gctttaattg
    25861 tggcggtcat ttcggttgtt attacctttg tattagctta tatatttgga atcgatgaag
    25921 aagagagttc tagcaattta gaagttgaag ctggagtttc aaataaaaaa atgatatttt
    25981 ctcctatatc aggagaaatc attccgttaa gcgatgtcca ggataaaaca ttttcagata
    26041 aactaattgg agacggagta gcgattatcc caagtgaagg taaggtttat gcaccatttg
    26101 atgggaaaat tacaaatatt tttccgacta agcacgcaat tggattgaag agtgatgagg
    26161 gtgttgagtt actaattcat attggattag atactgttga gctaaaaggt caaggtttta
    26221 ttagtcatgt agaagaagga gacagagttt tcaaaaatca gttgattttt gaaatggact
    26281 tgaatttaat caagactaaa ggctacgaaa cagttacacc agtaattgta acgaatacca
    26341 atgattttct agatgtatta gtattaccta ataatcagac aatcgagcat tctaaggaat
    26401 tactggtaat attataatgg aggaaagtta tgaccatttt tccagatgat tttctttggg
    26461 gtggagcggt tgcagctaat caagtagagg gagcatataa tgaagatggt aagggattat
    26521 cagttcagga tgtgttaccc aaaggtggat taggagaagc aacagaaaat cctacagaag
    26581 ataacttaaa attgttaggt attgattttt atcataaata taaggaagat atatccttgt
    26641 tttctgaaat gggctttaat gtttttcgta cttctattgc atggagtaga atttttccaa
    26701 aaggagatga agaagaacct aacgaagctg ggttgaaata ttatgatgaa ttatttgatg
    26761 aactacatgc tcacgggata gaaccacttg taactctttc acactatgag actccattat
    26821 atttagcaag aaaatatcat ggatggattg ataggagaat gattcatttt tatgaaaaat
    26881 ttgctcgaac agttttagaa aggtataaag ataaagttaa atattggctt acatttaacg
    26941 aagtaaactc tgttttggaa ttaccgttta ctagtggagg aatagatata cctaaggaga
    27001 atctttcgaa acaagaatta tatcaagcta tacatcatga attagtcgcc tcgagtttgg
    27061 ttacaaaaat tgctcgtgag attaattcag agtttaaggt ggggtgtatg gtattagcta
    27121 tgccagctta tccaatgact ccaaatccaa aagatgtatg ggcgactcat gagtatgaga
    27181 atctaaatta tctattttca gatgtgcatg ttagaggtta ttatccgaat tatgcaaaaa
    27241 gatattttaa ggaacatgac attaacatag agtttgcagc tgaagatgca gagttattaa
    27301 aaaattatac tgtagatttt ttatccttta gctattacat gagtgtgact caatctgctc
    27361 ttccaacaca gtataattca ggagaaggga atattattgg tggcttagta aatccttatt
    27421 tagagtcttc tgagtgggga tggcaaattg atccaattgg actacgtata attttaaata
    27481 gatattatga ccgttatcaa attccattat ttatagtgga aaacggatta ggtgctaaag
    27541 atcaactaat aaaagatgaa tttaataact taacagtcca agatgattat agaattcagt
    27601 atatggaaga acatttattg caagtagctg aagctctaca agatggtgtg gaaattatgg
    27661 gctatacatc ttggggatgt attgactgcg tttctatgtc cactgcacaa ctttctaaaa
    27721 ggtacggtct catttatgtt gatcgaaatg atgatggaaa tggcacattc aatcgatata
    27781 agaaaatgtc ctttacttgg tataaaggag tgattgaatc aaatggagaa tccttattca
    27841 aatagtttgt ttattgatga ttagatatta tcacggttaa ggcaacatct cattaaatat
    27901 gaaataaaga ggtttggaag acatcaaatt
//
LOCUS       DAVLXH010000024        27403 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00028199
            SAMN33607166-rid17955573.denovo.024, whole genome shotgun sequence.
ACCESSION   DAVLXH010000024 DAVLXH010000000
VERSION     DAVLXH010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607166
            Sequence Read Archive: SRR23725544
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 27403)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27403)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721421.1
            Genome Coverage       :: 115x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:42:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,210
            CDSs (total)                      :: 2,161
            Genes (coding)                    :: 2,023
            CDSs (with protein)               :: 2,023
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 73 of 138
            Pseudo Genes (incomplete)         :: 60 of 138
            Pseudo Genes (internal stop)      :: 40 of 138
            Pseudo Genes (multiple problems)  :: 31 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27403
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607166-rid17955573.denovo.024"
                     /strain="AUSMDU00028199"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1349"
     gene            complement(1..745)
                     /locus_tag="VYO11_001146"
                     /pseudo
     CDS             complement(1..745)
                     /locus_tag="VYO11_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611513.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(881..1180)
                     /locus_tag="VYO11_001147"
     CDS             complement(881..1180)
                     /locus_tag="VYO11_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HEV1595727.1"
                     /translation="MKLINTTNSHSQLVKSQLESTDATLVEVYSAGNTDVIFTQAPLH
                     YEILISNKHRAIREPEIETIQEFFLKRKIDKTSVDEANIKTLYSEKLIGISIPIK"
     gene            complement(1345..1796)
                     /locus_tag="VYO11_001148"
                     /pseudo
     CDS             complement(1345..1796)
                     /locus_tag="VYO11_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000013080.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
     gene            1878..2724
                     /locus_tag="VYO11_001149"
                     /pseudo
     CDS             1878..2724
                     /locus_tag="VYO11_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="programmed frameshift; internal stop; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            complement(2926..5184)
                     /locus_tag="VYO11_001150"
     CDS             complement(2926..5184)
                     /locus_tag="VYO11_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEV1595728.1"
                     /translation="MLCQNCKINDSTIHLYTNLNGKQKQIDLCQNCYKIIKTDPNNSL
                     FKGMTDLNNRDFDPFGDFFNDLNNFRPSSNTPPIPPTQSGGGYGGNGGYGSQNRGSAQ
                     TPPPSQEKGLLEEFGINVTEIARRGDIDPVIGRDDEIIRVIEILNRRTKNNPVLIGEP
                     GVGKTAVVEGLAQKIVDGDVPHKLQGKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEI
                     RKREDIILFIDEIHEIVGAGSASDGNMDAGNILKPALARGELQLVGATTLNEYRIIEK
                     DAALERRMQPVKVDEPTVDETITILKGIQKKYEDYHHVQYTDAAIEAAATLSNRYIQD
                     RFLPDKAIDLLDEAGSKMNLTLNFVDPKVIDQRLIEAENLKSQATREEDFEKAAYFRD
                     QIAKYKEMQKKKITDQDTPIISEKTIEHIIEQKTNIPVGDLKEKEQSQLIHLAEDLKS
                     HVIGQDDAVDKIAKAIRRNRVGLGTPNRPIGSFLFVGPTGVGKTELSKQLAIELFGSA
                     DSMIRFDMSEYMEKHSVAKLVGAPPGYVGYDEAGQLTEKVRHNPYSLILLDEVEKAHP
                     DVMHMFLQVLDDGRLTDGQGRTVSFKDAIIIMTSNAGTGKTEASVGFGAAREGRTNSV
                     LGELGNFFSPEFMNRFDGIIEFKALSKDNLLQIVELMLADVNKRLSSNNIRLDVTDKV
                     KEKLVDLGYDPKMGARPLRRTIQDYIEDTITDYYLENPSEKDLKAVMTSKGNIQIKSA
                     KKAEVKSSEKEK"
     gene            complement(5413..5643)
                     /locus_tag="VYO11_001151"
     CDS             complement(5413..5643)
                     /locus_tag="VYO11_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005592360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HEV1595729.1"
                     /translation="MESHLVRIINRLEAMANDGGNLKRNFEREGVVVAEVAYSHDEEN
                     GPIFTLRDVEDRETYTFDSIDLIAMEIYELLY"
     gene            5833..6516
                     /locus_tag="VYO11_001152"
     CDS             5833..6516
                     /locus_tag="VYO11_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001011621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV1595730.1"
                     /translation="MNFSFLPKYLPYFNYGAVVTILISICVIFLGTILGVVLAFGQRS
                     KFKPLVWLANLYVWIFRGTPMMVQIMIAFALMHINAPTIQIGILGVDFSRLIPGILII
                     SMNSGAYVSETVRAGINAVPKGQLEAAYSLGIRPKNAMRYVILPQAVKNILPALGNEF
                     ITIIKDSSLLSAIGVMELWNGATTVSTTTYLPLTPLLFAAFYYLIMTSILTVALKAFE
                     KHMGQGDKK"
     gene            6516..7250
                     /locus_tag="VYO11_001153"
     CDS             6516..7250
                     /locus_tag="VYO11_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV1595731.1"
                     /translation="MTETLIKIENLHKSFGKNEVLKGISLEIKRGEVVVIIGPSGSGK
                     STLLRSMNLLEEATKGKVIFEGVDITDKKNDLFAMREKMGMVFQQFNLFPNMTVMENI
                     TLSPIKTKGESREVAEKRAQELLEKVGLPDKADAYPQSLSGGQQQRIAIARGLAMEPD
                     VLLFDEPTSALDPEMVGEVLAVMQDLAKSGMTMVIVTHEMGFAREVADRVIFMADGVV
                     VEDGTPEQIFEQTQEQRTKDFLRKVL"
     gene            7404..8261
                     /locus_tag="VYO11_001154"
     CDS             7404..8261
                     /locus_tag="VYO11_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000192112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HEV1595732.1"
                     /translation="MTQIIDGKALAAKLQGQLAEKIAKLKEETALVPGLVVILVGDNP
                     ASQVYVRNKERSALAAGSRSEVVRVPETITQEELLDLIAKYNQDSAWHGILVQLPLPK
                     HIDEEAVLLAIDPEKDVDGFHPLNMGRLWSGHPVMVPSTPAGIMEMFHEYGIDLEGKN
                     AVVIGRSNIVGKPMAQLLLAKNATVTLTHSRTHNLAKVAAKADILVVAIGRAKFVTAD
                     FVKPGAVVIDVGMNRDENGKLCGDVDYEAVAPLTSHITPVPGGVGPMTITMLMEQTYQ
                     AALRTLDRK"
     gene            8403..9275
                     /locus_tag="VYO11_001155"
     CDS             8403..9275
                     /locus_tag="VYO11_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000864675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HEV1595733.1"
                     /translation="MKVINQTLLEKVIIERSRSSHKGDYGRLLLLGGTYPYGGAIIMA
                     ALAAVKSGAGLVTVGTDRENIPALHSHLPEPMAFSLQDQQLLKEQLEKAEVVLLGPGL
                     RDDASGENLVKQVFVNLSQNQILIVDGGALTILARTSLSFPSSQLILTPHQKEWEKLS
                     GITIEKQKEDATASVLTSFPQGTILVEKGPATRIWEVGQSDYYQLQVGGPYQATGGMG
                     DTLAGMIAGFVGQFRQASLYERVAVATHLHSAIAQELSQENYVVLPTEISRYLPKIMK
                     IICQQERVSKDKLV"
     gene            9557..10240
                     /gene="rpiA"
                     /locus_tag="VYO11_001156"
     CDS             9557..10240
                     /gene="rpiA"
                     /locus_tag="VYO11_001156"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HEV1595734.1"
                     /translation="MENLKKMAGIKAAEFVSDGMVVGLGTGSTAYYFVEEIGRRIKEE
                     GLQITAVTTSSVTSKQAEGLNIPLKSIDQVDFVDVTVDGADEVDSQFNGIKGGGGALL
                     MEKIVATPSKEYIWVVDESKLVDKLGAFKLPVEVVQYGAEQIFRRFERAGYKPSFREK
                     DGQRFVTDMQNFIIDLALDVIEDPIVFGQELDHVVGVVEHGLFNQMVDKVIVAGRDGV
                     QILTSRKEK"
     gene            10254..11465
                     /locus_tag="VYO11_001157"
     CDS             10254..11465
                     /locus_tag="VYO11_001157"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HEV1595735.1"
                     /translation="MSKFNRIHLVVLDSVGIGAAPDANNFVNAGVPDGASDTLGHISK
                     TVGLNVPNMAKIGLGNIPRETPLKTVAAESNPTGYATKLEEVSLGKDTMTGHWEIMGL
                     NITEPFDTFWNGFPEEILTKIEEFSGRKVIREANKPYSGTAVIDDFGPRQMETGELII
                     YTSADPVLQIAAHEDIIPLDELYRICEYARSITLERPALLGRIIARPYVGEPGNFTRT
                     ANRRDLAVSPFAPTVLDKLNEAGIDTYAVGKINDIFNGAGINHDMGHNKSNSHGIDTL
                     LKTMGLAEFEKGFSFTNLVDFDALYGHRRNAHGYRDCLHEFDERLPEIIAAMRENDLL
                     LITADHGNDPTYAGTDHTREYIPLLAYSPAFKGNGVIPVGHFADISATVADNFGVETA
                     MIGESFLDKLV"
     gene            11467..12009
                     /locus_tag="VYO11_001158"
     CDS             11467..12009
                     /locus_tag="VYO11_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1697 domain-containing protein"
                     /protein_id="HEV1595736.1"
                     /translation="MTRYALLVRGINVGGKNKVVMAELRQELTNLGLEKVESYINSGN
                     IFFTSIDSKAQLVEKLETFFAVHYPFIQSFSLLSLEDFEAELENLPAWWSRDLARKDF
                     LFYTEGLDVDQVIATVESLELKDEVLYFGKLGIFWGKFSEESYSKTAYQKYLLKVPFY
                     RHITIRNAKTFDKIGQMLKK"
     gene            12025..12834
                     /locus_tag="VYO11_001159"
     CDS             12025..12834
                     /locus_tag="VYO11_001159"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HEV1595737.1"
                     /translation="MTFLNKIHETATFLKEKGIAAPEFGLILGSGLGELAEEIENPVV
                     VDYAEIPNWGRSTVVGHAGKLVYGELAGRKVLALQGRFHFYEGNPLEVVTFPVRVMKV
                     LGCEGVIVTNAAGGIRFGPGTLMAISDHINMTGQNPLMGENLDDFGPRFPDMSRAYTP
                     EYRATAHEVAKKLNIKLDEGVYIGVTGPTYETPAEIRSYKTLGADAVGMSTVPEVIVA
                     AHSGLKVLGISCITNFAAGFQEELNHEEVVEVTERVKGDFKGLLKAILAEL"
     gene            13310..13705
                     /locus_tag="VYO11_001160"
     CDS             13310..13705
                     /locus_tag="VYO11_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000887334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="topology modulation protein"
                     /protein_id="HEV1595738.1"
                     /translation="MLDSKEELKESENDAPKLETPLREEPRLAPQTLPEASEVLENKR
                     EESKVEITEPAQADDIRKVVGELAKDISITKLYMTGHSLGGYLAQIAAVEDYQKYPDF
                     YNHVLRKVTTFSAPKVITSRTVWDAKNGF"
     gene            13715..14290
                     /locus_tag="VYO11_001161"
     CDS             13715..14290
                     /locus_tag="VYO11_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000445853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="discoidin domain-containing protein"
                     /protein_id="HEV1595739.1"
                     /translation="MESRKLAVSGKIKHYVVDNDNVVTPLIHNNRDIVTFTGNSRFKH
                     RSRGYFESPMNDIPNFNIGKQATLDKHGYRDPKLDKVRFFKKQALPRSSSQPSAEPME
                     NIALGKQVTQSSTVFGGDARRAVDGKVDGNYGHNSVTHTNFQSKPWWQVDLAKEETIR
                     QINIYNRTDTAQDRLANFDVILLDSSGKEIE"
     gene            14315..14737
                     /locus_tag="VYO11_001162"
     CDS             14315..14737
                     /locus_tag="VYO11_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001275925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin"
                     /protein_id="HEV1595740.1"
                     /translation="MSAQITINHKKVRYVRIELEGYNALSLAEVEVFRFIATNAETAT
                     QVSKPVQPISQTPVKDKTLTIQHSGAYIARYSITWEEVPVDKDGNQVVRSHSWEGNGC
                     NQTAGFVLNLPIKENMRNLRVKIEKKTGLLWNRWQTIY"
     gene            15481..16191
                     /gene="deoD"
                     /locus_tag="VYO11_001163"
     CDS             15481..16191
                     /gene="deoD"
                     /locus_tag="VYO11_001163"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HEV1595741.1"
                     /translation="MSIHIAAQQGEIADKILLPGDPLRAKFIAENFLDDAVCFNEVRN
                     MFGYTGTYKGHCVSVMGTGMGMPSISIYARELIVDYGVKKLIRVGTAGSLNEEVHVRE
                     LVLAQAAATNSNIVRNDWPQYDFPQIASFDLLDKAYHIAKELGMTTHVGNVLSSDVFY
                     SNYFEKNIELGKWGVKAVEMEAAALYYLAAQYHVDALAIMTISDSLVNPDEDTTAEER
                     QNTFTDMMKVGLETLIAE"
     gene            complement(16214..16738)
                     /locus_tag="VYO11_001164"
     CDS             complement(16214..16738)
                     /locus_tag="VYO11_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000684222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topology modulation protein"
                     /protein_id="HEV1595742.1"
                     /translation="MKIAIIGYSGSGKSTLAEKLSNYYSIPKLHMDTLQFQPGWQDSD
                     HEWMLTEIKNFLTKHKAWVIDGNYSWCYYQERMQEADQIIFLNFSPLTCLFRAFKRYL
                     KYRGKVRESMAADCPERFEWEFIRWILWDGRSKTQKENYQKLCQEYSHKVTILRNQRE
                     LDQFLDKKRKSYNS"
     gene            complement(16791..17027)
                     /locus_tag="VYO11_001165"
     CDS             complement(16791..17027)
                     /locus_tag="VYO11_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001274003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HEV1595743.1"
                     /translation="MANIKSAIKRAELNVKQNEKNSAQKSAMRTAIKAFEANPSEELF
                     RAASSAIDKAETKGLIHKNKASRDKARLSAKLAK"
     gene            complement(17095..18015)
                     /locus_tag="VYO11_001166"
     CDS             complement(17095..18015)
                     /locus_tag="VYO11_001166"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HEV1595744.1"
                     /translation="MTNEFLHFEKISRQTWQSLHRKTTPPLTEEELESIKSFNDQISL
                     QDVTDIYLPLAHLIQIYKRTKEDLAFSKGIFLQRESKSQPFIIGVSGSVAVGKSTTSR
                     LLQILLSRTFTDATVELVTTDGFLYPNQTLIEQGILNRKGFPESYDMEALLNFLDRIK
                     NGQDVDIPVYSHEVYDIVPEEKQSVKAADFVIVEGINVFQNPQNDRLYITDFFDFSIY
                     VDAGVDDIESWYLDRFLKMLSLAQNDPDSYYYRFTQMPIGEVEAFAHQVWTSINLTNL
                     QNYIEPTRNRAEVILHKSKNHEIDEIYLKK"
     gene            18213..18617
                     /locus_tag="VYO11_001167"
     CDS             18213..18617
                     /locus_tag="VYO11_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1595745.1"
                     /translation="MKILKRYILELCFILSFALPFIKGANADNGICFVETYYGFTFLM
                     EHAIVTAVFIYSFSIAFLLKKRWAKWIAAGSYCFLVLWIATEGYFFRMSLEDLIRLWT
                     SLEILTQTYQLGFYLNILLGILLIIKYFKVKQ"
     gene            18833..19414
                     /locus_tag="VYO11_001168"
     CDS             18833..19414
                     /locus_tag="VYO11_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEV1595746.1"
                     /translation="MYYAENPDAAHDIHELRVELLGQKMTFLTDAGVFSKKIVDFGSQ
                     LLLKCLEVNQGETVLDVGCGYGPLGLSLAKAYGVQATMVDINTRALDLARRNAEKNNA
                     KATIFQSNIYEQVEGHFDHVISNPPIRAGKQVVHEIIEKSKDFLETGGDLTIVIQKKQ
                     GAPSAKSKMEDVFGNCEILKKDKGYYILRSVKE"
     gene            19411..20688
                     /locus_tag="VYO11_001169"
     CDS             19411..20688
                     /locus_tag="VYO11_001169"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001202959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HEV1595747.1"
                     /translation="MRAVDLIQKKRDGQELTSSEIEWLIEGYVSGTVPDYQMSAFAMA
                     VYFKGMTTREISDLTMNMVKTGQEFDLSAIDGVKVDKHSTGGVGDKVTLILAPLVASF
                     GVPVAKMSGRGLGHTGGTIDKLESIRGYQVERSQEDFIRQVQDIGVSVIGQSDQLVKA
                     DKLLYALRDVTATVDTIPLIASSVMSKKIAAGADAILLDVTVGEGAFMKTVDEARELA
                     QTMVDLGKVVGRKTVAVITDMSQPLGRAIGNRLEILEALEILQGQGRQDITHFICELA
                     QIMLGLANVNKTVEEVRQHLEDGQALAKFEEMVQAQGGDLEDLYRPVNVAHVVEIPAQ
                     ETGVISALPAMDFGLYAMRLGAGRAVKSDALDYETGIVFEKKIGDSVQKGEIVAKVYT
                     NEKIPPQLVTDFQKCVKISDEVKKIREIVEIIS"
     gene            20706..21368
                     /gene="deoC"
                     /locus_tag="VYO11_001170"
     CDS             20706..21368
                     /gene="deoC"
                     /locus_tag="VYO11_001170"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HEV1595748.1"
                     /translation="MKLNKYIDHTLLKQDAKKKQIDSLLSEAREYGFASVCVNPTWVE
                     HAKKGLEGTDVKVCTVVGFPLGATTSAVKAFETKEAIQNGADEIDMVINVGALKSGNL
                     ALVESDIRAVVEASGDKLVKVIIEACLLTDQEKVVVCQLAQKAGADFVKTSTGFSTGG
                     ATIADVTLMRETVGSDMGVKAAGGARSYADALAFVEAGATRIGTSAGVAILKGELADG
                     DY"
     gene            21355..21744
                     /locus_tag="VYO11_001171"
     CDS             21355..21744
                     /locus_tag="VYO11_001171"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HEV1595749.1"
                     /translation="MATTELIELAIETSKHAYVPYSHFPIGAVLVAKDGNVYTGVNIE
                     NASYPLTNCGERTAIFKAISEGQREFSELIVYGQTEKPISPCGACRQVMVEFFEQDLK
                     VTLVAKDKSTVEMTVGELLPYSFTDLN"
     gene            21835..22887
                     /locus_tag="VYO11_001172"
     CDS             21835..22887
                     /locus_tag="VYO11_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family protein"
                     /protein_id="HEV1595750.1"
                     /translation="MNKKQWLGLGLVAVAAVGLAACGNRSSRNAASSSDVKTKAAIVT
                     DTGGVDDKSFNQSAWEGLQAWGKEHNLSKDNGFTYFQSTSEADYANNLQQAAGSYNLI
                     FGVGFALHNAVEEAAKEHTDLNYVLIDDVIKDQKNVASVTFADNESGYLAGVAAAKTT
                     KTKQVGFVGGIESEVISRFEAGFKAGVASVDPSIKVQVDYAGSFGDAAKGKTIAAAQY
                     AAGADIVYQVAGGTGAGVFAEAKSLNESRPENEKVWVIGVDRDQEAEGKYTSKDGKES
                     NFVLVSTLKQVGTTVKDISNKAEKGEFPGGQVIVYSLKDKGVDLAVTNLSEEGKKAVE
                     DAKAKILDGSVKVPEK"
     gene            23031..24566
                     /locus_tag="VYO11_001173"
     CDS             23031..24566
                     /locus_tag="VYO11_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000929819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1595751.1"
                     /translation="MAHENVIEMRDITKVFGGFIANDKINLHLRKGEIHALLGENGAG
                     KSTLMNMLAGLLEPTSGEIAVNGQVVNLDSPSKAASLGIGMVHQHFMLVEAFTVAENI
                     ILGSELTKNGVLDIAGASKEIKALSERYGLAVDPSAKVADISVGAQQRVEILKTLYRG
                     ADILIFDEPTAVLTPSEIDELMAIMKNLVKEGKSIILITHKLDEIRAVSDRVTVIHRG
                     KSIETVEIAGATNADLAEMMVGRSVSFKTEKQASKPKEVVLSIKDLVVNENRGVPAVK
                     NLSLDVRAGEIVGIAGIDGNGQSELIQAITGLRKVESGSIELKGDSIVGLHPRQITEL
                     SVGHVPEDRHRDGLILEMMISENIALQTYYKEPHSKNGILNYSNITSYAKKLMEEFDV
                     RAASELVPAAALSGGNQQKAIIAREIDRDPDLLIVSQPTRGLDVGAIEYIHKRLIEER
                     DNGKAVLVVSFELDEILNVSDRIAVIHDGKIQGIVSPETTNKQELGVLMAGGNLGKEK
                     SDV"
     gene            24559..25617
                     /locus_tag="VYO11_001174"
     CDS             24559..25617
                     /locus_tag="VYO11_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1595752.1"
                     /translation="MSKKLQQISVPLISVFLGILLGAIVMWIFGYDAIWGYEELFYTA
                     FGSLRGIGEIFRAMGPLVLIGLGFAVASRAGFFNVGLPGQALAGWILSGWFALSHPDM
                     PRPLMILATIVIALIAGGIVGAIPGILRAYLGTSEVIVTIMMNYIVLYVGNAFIHAFP
                     KDFMQSTDSTIRVGANATYQTPWLAELTGNSRMNIGIFFAIIAVAVIWFMLKKTTLGF
                     EIRAVGLNPHASEYAGISAKRTIILSMIISGALAGLGGSVEGLGTFQNVYVQGSSLAI
                     GFNGMAVSLLAANSPIGILFAAFLFGVLQVGAPGMNAAQVPSELVSIVTASIIFFVSV
                     HYLIERFVKPKKQVKGGK"
     gene            25620..26576
                     /locus_tag="VYO11_001175"
     CDS             25620..26576
                     /locus_tag="VYO11_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1595753.1"
                     /translation="MSIITLLPLLVSSMLIYSAPLIFTSIGGVFSERGGVVNVGLEGI
                     MVMGAFSGVVFNLEFAEQFGAATPWLSLLVAGLVGSVFSIIHAAATVHFRADHVVSGT
                     VLNLMAPALAVFLVKVLYNKGQTDNLSQTFGRFDFPVLANIPVIGDIFFKSTSLLGYL
                     AIAFSFLAWFILFKTQFGLRLRSVGEHPQAADTLGINVYKMRYLGIIISGFLGGIGGA
                     IYAQSISVNFSVTTIVGPGFIALAAMIFGKWNPIGAMLSSLFFGLSQSLAVIGSQLPF
                     LQGVPAVYLQIAPYVLTILVLAAFFGKAVAPKADGINYIKSK"
     gene            26661..27403
                     /locus_tag="VYO11_001176"
                     /pseudo
     CDS             26661..27403
                     /locus_tag="VYO11_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT         8043 a         4963 c         6071 g         8326 t
ORIGIN      
        1 atcaagtgtt gaactctttt atgatttacc agataaccac gatttcttag ttctaaataa
       61 atccgacgat aaccatagtt gcctttatgt tcattataaa tggcctgaat ttaggtttta
      121 atctctttat ctttatcaac cccatccagt tgtttcaact gataatagta agtcgagcga
      181 gctaaacgtg ctgtttcaag aagaaaatct agtcgaaatc ctcctgaaac catttctcta
      241 actgtctctg cctttctcgc tctagggctt cgtccctttc ctctaactct tttaactttt
      301 ttaggtaggc cacctcagtc cgtaagcgtt cattctcctc ctggagtcgt tctagttctg
      361 tcatttcttc ccaagtcttc ttccgtttac gtcccatttt agctggtctc cctcttgttt
      421 tctcaacaat agtatacccg tttttcttgt attgtgccag ccaaaatgaa agcattcctt
      481 ggtttgggag ggcataatca agactaacac ttctttgtga acaaccttcc agtaaggctt
      541 tatccatcat ttcttgtttc aatttagaag aatagtgacg attcttcccc tttttaacga
      601 tttctatgcc atgacggtca attaatttca ccatgtactt tagaccagaa acatccacac
      661 caaatctttt tgaaagctgt ttgaagcttt gtccttgctt tcttagttca tagatctgaa
      721 ctttatcttc ataacttaat ttcataataa aacaccccaa aagttagatt ttttctgtct
      781 aacttttagg gggcagttca tttcggcacc tgatactatg cgttttgtta tggaaagact
      841 tattggactt tctctcaaat cgagttttta ctcaattttc ttacttgatt gggattgaaa
      901 ttccaattaa tttctctgag tagagtgtct tgatattggc ttcatcaaca gaggtcttat
      961 caattttacg tttcaagaaa aattcttgaa tggtttcgat ttcaggctca cgaatagcac
     1021 ggtgtttgtt tgagatgagg atttcatagt gaagcggagc ttgggtaaaa ataacatctg
     1081 tattccctgc agaataaacc tcaacaaggg ttgcatcggt actttctagt tgacttttta
     1141 caagttgcga gtgtgagttt gtcgtattga taagcttcat aatatttcct ccgattttct
     1201 aattctatta taacactttt tgaataaagt cgcttgattt atactcaatg aaaatcaaag
     1261 agcaaactag gaagctagcc gcaggctata cttgagtacg gtaaggcgac gcttacgtga
     1321 tttgaatttt attttcgaag agtattagcc aatcttatgc tgttttttcc aagattcaat
     1381 ggcccattta tggctgccac gtttaaggtt tttgatagcc tcgtcaatag ggaaccaggc
     1441 aatatgatta aagttttcta gtggcttttg tacttctttg aaaggagttg cttcatagag
     1501 gtaggcagga ttgtagtagt aggtatcacg atgacgagaa tagaaatatt cgtcagctgg
     1561 tccgtaatag gtaccaattt ctgctgtgaa accaagctct tcaatcaact cacgctttag
     1621 ggcttcctga tgattttcac ctgcttcaat ttttccacat ggtaggaacc aagcaccatt
     1681 tggttcttga acaagaacaa tttgtttttg ttcaggatta gggataactg catatacgcc
     1741 atagcgagca atatagtctg tattcacttt ttttctccga aagttgggtt tgccattgca
     1801 ttttcctcat tatctagtat cgttattatt atagtgaaat gaaccaaaaa tagtacacaa
     1861 tgtggtataa tcttcttatg gcatattcaa tagattttcg taaaaaagtt ctctcttatt
     1921 gtgagcgaac aggtagtata acagaagcat cacacgtttt ccaaatctca cgtaatacca
     1981 tttatggctg gttaaagcta aaagagaaaa caggagagct aaaccaccaa gtaaaaggaa
     2041 caaaaccaag aaaagttgat agagatagac ttaaaaacta tcttactgac aatccagacg
     2101 cttatttgac tgaaatagct tctgaatttg gctgtcatcc aactaccatc cactatgcgc
     2161 tcaaagctat gggttacact cgaaaaaaag aaccacacct actatgaaca agagccagaa
     2221 aaagtagcct tatttcttaa gaattttaat agattaaagc acctagcacc tgtttagatt
     2281 gacgaaacag gattcgatac ttatttttat cgagaatatg gtcgctcatt aaaaggtcag
     2341 ttaataagag gtaaagtatc tggaagaaga tatcagagga tttctttggt tgcaggtcta
     2401 acaaatggtg agttaatcgc tccaatgact tacgaagaga tgatgacgag cgactttttt
     2461 gaagcttggt ttcagaagtt tttcttacca acattaacca caccatcggt tattattatg
     2521 gataatgtaa gattccatag aatggggaag ctagaacttt tatgcgaaga gtttgggcat
     2581 aaacttttac ctcttcctcc ctactcgcct gagtacaatc ctattgagaa aacatgggct
     2641 catatcaaaa agcacctcaa aaaggtatta ccaagttgca atacctttta cgaggctctt
     2701 ttgtcctgtt cttgtttcaa ttgactatag cagattgaaa tgagaacaaa tcgattggga
     2761 aagtaaaatt aatttctata aatgttttag caattgtttc gtactatttc agattcagtc
     2821 tactatatat cataatggac aaagggcaag ctgtcaagaa attacagtta ttttagtaaa
     2881 aaaagaagca gaaaaatttc attttctact ccttttctat aggatttatt tttctttttc
     2941 agaactttta acttcagctt ttttggcaga tttaatctga atgtttccct tgctagtcat
     3001 aactgctttg agatcttttt cgcttggatt ttcaaggtag tagtcagtga ttgtgtcctc
     3061 aatatagtct tgaatagtcc gacgaagtgg gcgtgctccc atttttggat cataacctag
     3121 gtcaaccaac ttttccttga ccttatcagt tacatccaaa cgaatgttgt tgctagagag
     3181 gcgcttgtta acatctgcta gcatgagctc gacaatctga aggaggttat ccttgctgag
     3241 agccttaaat tcgataatgc catcaaaacg gttcataaac tctgggctaa agaagttacc
     3301 gagttcaccg aggacagaat tggtacgtcc ttctctagca gcaccaaatc caacgctagc
     3361 ttcggtcttt cctgtacctg catttgaggt catgataatg atggcatcct tgaagctaac
     3421 ggtgcgtcct tgcccgtctg tcaaacgacc atcgtccaag acttgaagaa acatgtgcat
     3481 aacatctggg tgagcttttt ccacttcatc gagaaggatg agagaatatg gattgtggcg
     3541 aactttttca gttaattgac cagcctcatc atagccaaca taacctggag gggcgccgac
     3601 caacttagcc acactatgtt tttccatgta ttcactcata tcaaagcgaa tcatactatc
     3661 agcagaacca aaaagttcga tagccagttg tttggaaagt tctgtcttac cgacaccagt
     3721 tggcccaacg aagaggaagc ttccgattgg gcggttaggg gtaccaagtc cgacacgatt
     3781 acggcgaata gccttggcaa tcttatcgac tgcatcatct tggccaataa catgagactt
     3841 gagatcttcg gctagatgga tgagttgaga ttgttctttc tctttcaaat caccaacagg
     3901 gatattggtt ttctgctcga taatgtgctc aatagttttc tcgctgatga taggagtatc
     3961 ctggtctgtg atctttttct tttgcatttc cttatacttg gcaatctggt cgcggaagta
     4021 ggccgccttc tcaaaatctt cttctcgtgt agcttgagac ttgagatttt cagcctcaat
     4081 caagcgctga tcaattactt taggatccac aaaattcaag gtcaagttca tcttagaacc
     4141 agcttcatct aggaggtcaa tggccttgtc aggcaagaag cgatcttgga tgtagcgatt
     4201 ggaaagagtt gcagctgctt caatcgcagc atcggtatat tgaacgtggt ggtaatcttc
     4261 gtatttcttt tgaatccctt tgagaatagt gattgtttca tccaccgttg gttcatcgac
     4321 tttaacaggc tgcatacgac gctcgagggc agcatccttt tcaatgatac ggtattcatt
     4381 gagggtagta gcaccgacta gttgcagttc tccacgagca agggctggct tgaggatatt
     4441 tcctgcgtcc atattaccat cactcgcaga accagcacca acaatttcat ggatttcatc
     4501 gataaagagg atgatgtctt cacgtttgcg aatttcttcc atgagttttt gcatgcgttc
     4561 ttcaaattgt cctcgaatcc ccgttccttg aactaagcta accacatcca gacggatgac
     4621 ttgtttacct tggagtttat gtggcacatc gccatcgaca attttctgag ctagaccttc
     4681 gacaacggcc gtttttccga caccaggttc accgataagg acaggattat tcttggttct
     4741 acgattgaga atctcgatga cacggataat ctcatcgtcg cgcccaataa cggggtcaat
     4801 gtctccacga cgggcaattt cagttacatt aataccaaat tcttccagca ggcctttttc
     4861 ttggctaggt ggcggagttt gagcagatcc acgattttgg gaaccataac cgccgtttcc
     4921 accgtaacct ccacctgatt gggttggggg aataggagga gtattgctag aaggtctgaa
     4981 attgtttaga tcattgaaga aatcaccaaa gggatcgaag tcacgattgt tcagatccgt
     5041 catacctttg aagaggctat tgttaggatc tgttttgata atcttatagc agttttgaca
     5101 gaggtcaatt tgtttttgtt ttccattgag attggtgtaa agatgaattg ttgagtcgtt
     5161 aattttacag ttttgacaaa gcatacatct acctcatttc tttctttagc ctgacttgtt
     5221 taaaggtcaa aaatagtcaa attctatact ctcattataa caggattggg gtgtaaagca
     5281 agtaaaaaga ttgaagcttt gagaagttgt tacaatgaaa atttttgtga atttggacta
     5341 taaaaaaatc ctatttgtga gacaaaaagg attttactta gacatgcagg gacaatccca
     5401 gcttgtttta gattagtaga gaagttcgta aatttccatt gcgattaagt caatgctatc
     5461 aaacgtatac gtttcgcgat cttctacgtc acgaagggta aagattgggc cgttttcttc
     5521 gtcgtggctg tacgcaactt ctgcaacaac aactccttcg cgttcaaaat tacgttttaa
     5581 atttccgcca tcgtttgcca ttgcttcaag gcggttgatg attctaacca aatgtgattc
     5641 cattttgatt ctccttcatt tcttatcgtt actattttac cataaaggag gccaacttga
     5701 ctagaaaaaa ctaagatttc tcgctaattc tgctagttta aagattttta aataaattgg
     5761 ataaaaaatt taaattttaa ttcaaaacat gttataatca tacagtattc tattttagaa
     5821 agcagtgtga ctatgaattt ttctttttta cctaagtatt taccttattt taactatggg
     5881 gctgttgtga cgattcttat ttctatctgt gttatctttt tgggaactat tttgggtgtt
     5941 gtcttggctt ttgggcaacg ttcaaagttt aaaccgcttg tttggttggc caacttgtac
     6001 gtttggattt tccgtgggac accgatgatg gttcaaatta tgattgcctt tgctcttatg
     6061 catatcaatg ctccgactat tcagattgga attttaggtg ttgatttttc gcgtctgatt
     6121 ccagggattt tgattatctc tatgaatagt ggtgcttatg tttcggagac tgttcgtgcc
     6181 ggaatcaatg cggttccaaa aggtcagcta gaggcggctt attcgctagg gattcgtcct
     6241 aaaaatgcga tgcgttatgt gattttgcca caagcagtca aaaatatctt gccagcattg
     6301 gggaacgaat ttatcaccat tatcaaggac agctccctct tatcagctat tggggtcatg
     6361 gagttgtgga atggggctac aacagtttct acaacaacct atctaccttt aacaccactt
     6421 ttatttgcag cattttacta cttgattatg acctctattc tgacagtagc cttgaaagct
     6481 tttgaaaaac atatgggaca aggagataag aaataatgac agaaaccttg ataaaaattg
     6541 aaaatttaca taaatctttt ggaaagaatg aagtattgaa gggcatcagc ctcgagatta
     6601 aaagaggaga agttgtcgtt atcatcggtc cttcagggag tgggaaatct accttgcttc
     6661 gctctatgaa tttgttggag gaagcaacca aggggaaggt tatctttgag ggagtcgata
     6721 ttacggacaa gaagaatgac ctgtttgcca tgcgtgagaa gatgggcatg gttttccaac
     6781 aatttaacct ctttcctaat atgactgtga tggaaaatat taccttgtca cctatcaaga
     6841 ctaaaggtga aagcagggaa gttgctgaga agagagccca agagcttttg gaaaaagttg
     6901 gtttgccaga taaggcagac gcttatccac agagtctgtc gggtgggcaa caacaacgga
     6961 ttgccatcgc gcgtgggttg gctatggaac cagatgtttt gctctttgac gaaccaactt
     7021 cagccttgga tcctgaaatg gtaggtgagg tattggctgt tatgcaagac cttgccaagt
     7081 cagggatgac tatggttatc gtaacacatg agatgggatt tgcccgtgag gtggcagatc
     7141 gtgttatctt tatggcagac ggtgtggttg ttgaagatgg gacacctgag cagatttttg
     7201 aacaaaccca agaacaacgg actaaagatt tcttgagaaa ggttttataa tctattttaa
     7261 aatttcaaga caagattagt gaaaagttca accagagctt tttcttatag tttgaaacta
     7321 taggataacc taggaaagaa gtgttagagg gcactagcag tttttggtat aatggaagat
     7381 atttgaaaga aaagagaagt gatatgacac agattattga tggaaaagct ttagcggcca
     7441 aattgcaggg gcagttggct gaaaagattg caaaattaaa ggaagaaaca gctctagtgc
     7501 ctggtttggt agtgattttg gttggggata atccagccag ccaagtctac gttcgcaaca
     7561 aggagaggtc agctcttgcg gctggttccc gtagcgaagt agtgcgagtt ccagagacca
     7621 ttactcaaga ggaattgtta gacctgattg ctaaatataa tcaggattca gcttggcatg
     7681 ggattttggt ccagttgcca ttaccaaaac atatcgatga agaggcggtt ttattagcca
     7741 ttgacccaga aaaggatgtg gatggtttcc atcccctaaa catgggacgt ctttggtctg
     7801 gacatccagt catggttccc tcgacacctg caggaattat ggaaatgttt catgaatatg
     7861 ggattgactt ggaaggtaaa aatgcggtcg taatcggtcg ttcaaatatc gttggaaaac
     7921 ctatggctca gcttcttttg gctaaaaatg cgacagtaac cttgacccac tcacgaactc
     7981 ataatcttgc caaggtggct gctaaagcag atattcttgt agtcgcaatc ggccgcgcca
     8041 agtttgtgac tgctgacttt gtcaaaccag gtgcggttgt cattgacgtt gggatgaacc
     8101 gagatgaaaa tgggaagctc tgtggagatg ttgattatga ggcagttgca ccacttacta
     8161 gccatatcac gccagtccct ggaggtgtcg gtcctatgac cattaccatg ctgatggagc
     8221 aaacttatca agcagcactt cggacattgg atagaaaata agagaaacat tcgattaata
     8281 gagtgtattt tctatagcta tatctaaaat ggcagaaatg aatattaaat tttagatata
     8341 agattacaaa aggaggtctg cgtctccttt ttattgtata ataaaagtga gaggaaaaaa
     8401 ggatgaaagt gattaatcaa accttattag aaaaagttat tattgaacgt tctcgttcaa
     8461 gtcataaagg agattatggt cgtctgctgc tgcttggtgg tacttatcct tatggaggtg
     8521 ccatcatcat ggctgcttta gcagctgtaa aaagcggtgc aggattggtg accgttggaa
     8581 cggacaggga aaatatcccg gctctgcaca gccatttacc tgagcctatg gccttttctc
     8641 ttcaagacca gcaattgtta aaagagcaat tggagaaggc agaagttgtc ttgctggggc
     8701 ctggtttacg agacgatgct tctggagaaa atctagtaaa acaggtcttt gttaatttaa
     8761 gccaaaatca gattttgatt gtagacggag gtgccttgac cattcttgct aggacaagtt
     8821 tgtcatttcc ctcaagccag cttatcctaa ctcctcacca aaaagaatgg gaaaaattat
     8881 ctggaattac gattgaaaag caaaaggaag atgcaacggc tagtgttctg acttccttcc
     8941 ctcaaggaac aattttggtg gagaaaggcc cagctactcg tatttgggaa gttggccaat
     9001 ctgattatta ccagttacag gttggtggtc cttatcaggc gactggggga atgggagata
     9061 ctctggctgg gatgatcgca ggatttgtag gccaattccg acaggccagt ctctacgagc
     9121 gtgtggcagt agcgacccat cttcattcag ccatagccca agaactatct caagaaaatt
     9181 atgtggtctt accgacggaa atcagcaggt atcttcccaa aataatgaaa attatttgtc
     9241 aacaagagag ggtaagtaaa gataaacttg tttaaaatag acagataaat ctacttcctt
     9301 ctcttaattt atgattcttg aaatgcgcct gctttaaggc taaactagac gtatcaaagt
     9361 taagagtttg tttttgtaac tggaaagaga tgaacaaatc aaatacataa aagataaact
     9421 catttttatt cgtttggtga aaagaaaata catattttta aagaaagatt gatgaaaaat
     9481 gtagatttga tgtttttact tgaataaaaa gcggtttcat agtaaaataa gaactgagaa
     9541 tgatggaggt aaatcggtgg aaaatctgaa gaaaatggca ggtatcaagg ctgctgagtt
     9601 cgtgagcgat ggaatggtcg ttggactggg aacgggttct actgcctatt attttgtcga
     9661 agaaattggt cgtcgtatca aggaagaagg attgcagatt acagctgtaa cgacttctag
     9721 tgtgaccagt aaacaggctg aagggcttaa cattccactc aagtctattg accaagtaga
     9781 ctttgtcgat gtgacagtcg acggagcgga tgaagtagat agtcagttta atggaatcaa
     9841 aggcggtggt ggtgcccttc tgatggagaa gattgttgca acgccctcaa aagaatacat
     9901 ttgggtagtg gatgaaagca agctggtaga caaactaggt gcttttaaat tgcctgtgga
     9961 agtggttcaa tatggtgcag aacagatttt tcgtcgtttt gagcgagctg gctacaaacc
    10021 aagtttccgt gaaaaagatg gccaacgttt tgtgaccgat atgcagaact ttatcattga
    10081 ccttgccttg gatgtcatcg aagatccaat tgtttttgga caagaattgg accatgtcgt
    10141 tggtgttgta gaacacggtt tattcaacca aatggtggac aaggtcattg ttgctggacg
    10201 agatggggtt cagattttaa cctcaagaaa agaaaaatag aagggggcat aagatgtcta
    10261 aatttaatcg tattcacttg gtggtattgg attctgtagg aattggtgct gcaccagatg
    10321 ctaataactt tgtcaatgca ggggttccag atggtgcctc tgacacactg ggacacattt
    10381 ccaaaaccgt tggtttgaat gtcccaaaca tggctaaaat cggtcttgga aatattcctc
    10441 gcgaaacgcc tttgaagact gtagcagctg aaagcaatcc aacaggatat gcgacgaaat
    10501 tggaagaagt atcccttggt aaggatacca tgactggtca ctgggaaatc atgggactca
    10561 acattacgga gcctttcgat actttctgga acggattccc agaagaaatc ctgacaaaaa
    10621 tcgaagaatt ttcaggacgt aaggtcattc gtgaagccaa caaaccttac tcaggaacag
    10681 ctgttattga tgactttgga ccacgtcaga tggaaactgg agagttgatt atctatactt
    10741 cagctgaccc tgttttacaa attgctgccc acgaagacat cattcctttg gatgaattgt
    10801 accgtatctg tgaatacgct cgttcgatca ctcttgagcg ccctgccctt ctaggtcgta
    10861 tcattgctcg cccttatgta ggtgaaccag gtaacttcac tcgtacagcc aaccgtcgtg
    10921 acttagccgt ttctccattt gcaccgactg ttttggataa attgaatgaa gctggtatcg
    10981 atacttacgc tgttggtaaa atcaacgata tctttaacgg tgctggtatt aaccatgaca
    11041 tgggtcacaa caagtcaaac agccatggaa ttgatacact attgaagacc atgggtcttg
    11101 ctgagtttga aaaaggattc tcattcacaa acttggtgga ctttgatgcc ctttacggcc
    11161 accgtcgtaa tgctcatggt tatcgtgatt gcttgcatga gtttgatgaa cgcttgcctg
    11221 aaattatcgc agctatgaga gagaatgacc ttctcttgat tactgcggac cacgggaacg
    11281 acccaactta cgcaggaaca gaccacactc gagaatatat cccacttttg gcttacagtc
    11341 ctgcttttaa aggaaatggt gtcattccag taggacattt tgcagatatt tcagcgactg
    11401 ttgctgataa ctttggtgtg gaaactgcta tgattgggga aagtttctta gataaattgg
    11461 tataagatga cgcgctatgc tttgctggtg agaggtatca atgttggtgg taagaataag
    11521 gtcgtcatgg cggagcttcg tcaagaattg acaaacttgg gactggaaaa ggttgagagc
    11581 tacatcaaca gtggcaatat tttctttact tcgatagatt ccaaagccca attggttgaa
    11641 aagctagaga ctttctttgc agtccattat ccatttattc agagcttttc tttactgagt
    11701 ctagaggact ttgaggcgga acttgaaaat ctaccagctt ggtggagcag agatttggca
    11761 cgaaaagatt ttctctttta cactgagggt ttggatgtgg accaagtcat cgcgacagtt
    11821 gaaagtttag agctgaaaga tgaagtgctt tattttggaa aacttgggat tttctggggg
    11881 aaattttctg aagaatccta ttctaagact gcctatcaga agtacttgct gaaggtgcct
    11941 ttctaccgcc acattactat tcgtaatgct aaaacctttg acaaaattgg tcaaatgcta
    12001 aaaaaataat aaaggagaca cacaatgaca tttttaaaca aaatccatga aactgctact
    12061 ttcctgaaag aaaagggaat tgcagcccct gagttcggtc taatccttgg atcaggactt
    12121 ggagaattgg cagaagaaat cgaaaatcca gttgtagtag actatgctga gattccaaac
    12181 tggggccgtt caacagtagt cggtcatgct ggtaaattgg tatatggtga actggcaggt
    12241 cgcaaggtct tggctcttca aggtcgtttc catttctatg aagggaatcc tctggaagtg
    12301 gtgactttcc cagttcgtgt gatgaaagtt cttggatgtg aaggtgttat tgtaaccaat
    12361 gcagctggcg gtatcagatt tggtcctggt accttgatgg ctatctcaga ccatatcaac
    12421 atgacggggc aaaatccatt gatgggtgaa aacttggatg actttggccc acgtttccca
    12481 gatatgtcta gggcctacac accagaatac cgtgccactg cccatgaagt ggctaaaaaa
    12541 cttaatatca agcttgatga aggtgtctat atcggagtta ctggtccgac ttatgaaaca
    12601 ccagcagaaa ttcgttccta taagacactg ggagcagatg cagttggtat gtctacggtt
    12661 cctgaagtta tcgtggcagc ccactctggc ttgaaagttc tgggaatttc atgtatcact
    12721 aactttgcgg ctggtttcca agaagaactc aatcacgaag aagttgtaga agtgactgaa
    12781 cgtgttaaag gtgatttcaa aggcttgctt aaagcgattc ttgctgaatt gtaagaaaaa
    12841 agatttaaaa ggggtagtgc ctctgtcttt tcaggattga ctgcctatcc gtattaaaga
    12901 agaaacagag gaatactatg agcttcttcc tgctcttata actgaaagaa gcggaagaat
    12961 aggtatgtct gatctgatag ccagcattgt gaaagacaag attctaggat actagcatta
    13021 gctttctagc caagcagact agtatgataa ggagagatga gaatgaattg actttctgaa
    13081 tttctcagtc ttatcatata tagcacaatg agatttcgct tgagtctgct tgtaaataaa
    13141 cgaaaagaaa gataataaat aatgaaaatt ggtcaacgaa ttatgcgctt tggtataaaa
    13201 aattaagtat cggagttgta tctgttgtag tcggctttga tttctagctc cagctggaat
    13261 ttcagccaat gaagtaaagc aagatgtaac atctgaagtg gtaataggtg tgctagattc
    13321 taaggaggaa ttgaaagagt cagaaaatga tgctccaaaa ctagaaactc ctcttagaga
    13381 ggagccaaga ctagctcctc aaacgcttcc ggaagcaagt gaagttcttg aaaacaaaag
    13441 ggaagagtca aaagtagaga taacagagcc agctcaagcg gatgatatcc gcaaggttgt
    13501 tggggaatta gccaaggata taagtattac taagttgtat atgacaggtc attctcttgg
    13561 aggctaccta gctcagattg cagcggttga agattaccaa aaatatcctg atttttataa
    13621 ccatgtattg aggaaagtga caactttcag tgctcctaaa gtcattactt ccagaactgt
    13681 ttgggatgct aagaatggtt tctgagatgt tggtttggaa agtcgtaaat tagctgttag
    13741 tggaaaaatt aagcattatg tggttgataa tgacaatgtt gtgactccct tgattcataa
    13801 taatcgtgat attgttacat ttacaggtaa ttcacgcttt aaacaccgtt ctcgtggcta
    13861 ttttgaaagt ccaatgaatg atattcctaa ctttaatatt ggtaaacaag ctaccttgga
    13921 taaacatggt tatcgtgatc cgaaattgga taaagtgcga ttctttaaga aacaggctct
    13981 gcctcgatct tctagtcaac caagcgctga accaatggaa aatattgcct taggaaaaca
    14041 ggttactcaa agttcgacag ttttcggagg agatgctaga agagctgtgg atggcaaagt
    14101 cgatggtaac tatggtcaca attctgtcac tcatacaaac ttccaatcta agccttggtg
    14161 gcaagtagat ttggctaaag aagaaaccat tcgccaaatc aatatttaca accgaacaga
    14221 cactgcccag gatagattgg caaactttga tgtcattctt ttagacagtt ctggtaaaga
    14281 aattgagtga aaacgtataa catctcctaa agatgtgtca gcacaaatta cgattaacca
    14341 taaaaaagtg cgctatgttc ggattgagct agaaggctat aatgccctca gtcttgcaga
    14401 agttgaagtt ttccgcttta tagctacgaa tgctgaaacg gcgacacaag tttctaagcc
    14461 agttcaacca atcagtcaga ctcctgtgaa agataaaaca ttgacaattc aacacagtgg
    14521 agcttacatt gcccgctact ccataacttg ggaagaagtt ccagtagata aagatggaaa
    14581 ccaagttgtt cgtagtcatt cttgggaagg aaacggttgc aaccagactg caggttttgt
    14641 cctcaacctc ccaatcaaag aaaatatgag aaatctgcga gttaagattg agaaaaagac
    14701 gggcctacta tggaatagat ggcaaacaat ctattaaaac agaccaattt tagctcaact
    14761 ccaccgtaaa attacccatt ggggtacgac attgaattcc aaggtgagtg acgatgatgt
    14821 cttgtaatct gatggtacaa tgacagttag tttgtctagt ttataagaaa gtactacctg
    14881 agcttgaata gaactcaggt agctctctgt gaaagaacaa aattaatact caatgaaaat
    14941 caaagagcaa actaagaaac tagccgcagg ttgctcaaag cactgctttg aggttgtaga
    15001 taagactgac gaagtcagtc acatatataa tccaaggcga cgttgacgtg gtttgaagag
    15061 attttcgaag agtataaaca gaaaggtaga gcgcgtgttc taatttgaac acgagtagaa
    15121 aacttttcta aaaacaaaaa cgaaaggatg ggtaaactgt attcgctgaa ctgaatacgg
    15181 gcgactctcc tctaaatcaa aattaagaaa ggaattgacc ccaccctaaa agtagtggga
    15241 aaaagatagt tgatctagcg agcatcgctc actgcgccca actcctattt tcccttcgct
    15301 ttttgatggg tttggtatct ttctcaatat aaaatataaa ataaagaaag gtagagcgtg
    15361 tgttttgatt tgaacacgag cggaaaactc ggaaaataga taatctgact gaaaaatcag
    15421 gatttctcgt caggttccta attttcagtc gttttcttct cgctctttgt atcataaatt
    15481 atgtctatcc atattgctgc tcagcagggt gaaattgctg ataaaattct tcttcctggg
    15541 gatcctcttc gtgctaagtt tattgcggag aatttccttg atgatgctgt ttgttttaac
    15601 gaagtgcgta acatgtttgg ttacactggt acttacaagg gtcactgtgt atctgtcatg
    15661 ggaactggga tgggaatgcc atctatttcg atttatgcgc gtgagttaat cgtagactac
    15721 ggtgtgaaga aattgattcg tgtgggaact gcaggttctt tgaatgaaga ggttcatgtt
    15781 cgtgaattag ttttggcgca ggcggctgca accaactcaa acatcgttcg taatgactgg
    15841 ccacagtacg attttccaca aattgctagc tttgatttgc ttgataaagc ctaccatatc
    15901 gccaaagaac ttggtatgac tactcacgtt gggaacgttt tgtcatctga tgtcttttac
    15961 tcaaattact ttgaaaagaa tatcgagctt ggtaaatggg gagtcaaggc tgtggaaatg
    16021 gaagcagcag ctctttacta tcttgctgcc caataccatg ttgatgcgct agctatcatg
    16081 accatctctg atagcttggt caatccagac gaagacacaa ctgcagaaga acgtcaaaat
    16141 accttcactg atatgatgaa ggttggtttg gaaaccttga ttgcagaata attatagcca
    16201 aaaaggaagc cctttatgaa ttgtaggact tccttttctt atccagaaat tgatctagct
    16261 ctctctgatt tcgaagaata gtgactttat gtgaatattc ttggcaaagt ttttggtaat
    16321 tttctttttg agttttgcta cgcccatccc aaagaatcca tctgataaac tcccactcaa
    16381 agcgttcagg gcaatctgcc gccatacttt ctctgacttt tccacggtat ttaagataac
    16441 gcttaaaggc tctaaagaga caggtcaatg gcgaaaaatt gagaaagatg atttggtcag
    16501 cttcttgcat tcgttcttgg tagtagcacc aagaataatt accatcgatg acccaagctt
    16561 tatgcttggt gagaaagttt tttatctcgg ttaacatcca ttcgtggtca ctgtcttgcc
    16621 aaccaggttg aaattggagt gtgtccatgt gcagttttgg aatggagtag tagttagata
    16681 acttttctgc tagagttgac ttaccagaac cagaatatcc gataattgcg attttcattt
    16741 tctacctttt cccatttgga gacaaaaaaa cagcctctat ggactgtttc ttatttagca
    16801 agtttagctg aaagacgagc tttatcgcgg cttgctttgt ttttgtgaat caaaccttta
    16861 gtttctgctt tatcgatagc tgagctagca gcacggaaaa gttcttcaga tgggtttgct
    16921 tcgaaagctt ttatagcagt acgcatagct gatttttgag ctgagttctt ttcgttttgt
    16981 ttaacgttca attcagcgcg tttgatagct gatttaatgt ttgccaatgt tcttacctcc
    17041 atatttacta actataccat tatatatgaa aacttacgtt ttgacaaggg aaaattactt
    17101 ttttaagtaa atttcatcga tttcatggtt cttgctttta tgaagaatca cttctgcacg
    17161 atttctggtt ggttcaatat aattttgtag atttgtgaga ttgatactgg tccagacctg
    17221 atgggcaaag gcttccactt ccccaatcgg catctgagta aaacgataat agtagctatc
    17281 agggtcgttt tgggctagac tcagcatttt caagaaacgg tccagatacc aactttcaat
    17341 atcatccact ccagcatcta catagatgga aaagtcaaag aagtcagtga tatagagacg
    17401 atcgttttgt ggattttgaa agacattgat tccctcaaca attacaaaat cagcagcttt
    17461 gacactttgt ttctcttcgg gtacgatgtc gtaaacttca tgagaataga caggaatatc
    17521 tacatcttgt ccatttttga tgcggtccaa gaagttgaga agagcttcca tatcatagct
    17581 ttcaggaaat cctttacgat ttaaaatccc ctgctcaatc aaggtttgat tgggatagag
    17641 aaaaccatca gttgtaacca actcaaccgt agcatctgta aacgtacggg acagtaggat
    17701 ttgaagtagg cgactggttg tggattttcc aacggcaaca ctcccagaaa ccccaataat
    17761 aaaaggttga gatttacttt cacgttggag gaaaattcct tttgaaaagg ctaaatcttc
    17821 cttagttcgc ttgtaaatct gaatcagatg agccaagggg agatagatat ctgtaacgtc
    17881 ttggagactg atttggtcat taaaactctt gatagattcc aattcttctt ctgtcaaagg
    17941 aggtgttgtc tttcgatgta aagattgcca agtctggcgg ctgatttttt caaaatgtaa
    18001 aaattcgttg gtcatttgtt ttcccctaga tattttgtct atcataccat aaaaatctaa
    18061 aaaaataaag cggtttcttg aatgtggtaa gtcaatggta tatagtataa gtgatcaatt
    18121 tattgatgaa ataggagata gattctactg atttataagt ttataagctt ataaaggggg
    18181 ctttttagtt cacaacttat aggaggtgta ctatgaaaat cttaaaacgt tacatattgg
    18241 aactctgttt tattttaagt tttgctttac cttttataaa aggagccaat gcagataatg
    18301 gtatatgctt tgtggaaacc tattacggtt ttactttttt gatggaacat gctattgtaa
    18361 cagctgtctt tatctattcg ttttcaattg ctttcttact aaaaaaacga tgggcgaaat
    18421 ggattgctgc tggtagttat tgctttttag tcctatggat tgcgacagag ggttatttct
    18481 tccgcatgtc actagaagat ttgatacgac tttggacaag tttggaaatc ctgacacaaa
    18541 cgtatcagtt gggcttttat ctaaacattt tgttgggaat tttgttgata ataaagtatt
    18601 ttaaggttaa gcaatagaaa taataatctg cctgattata gatgataaac tttttgtttt
    18661 tatctggact gtgatattta tagttctaaa tggtttatta tttataagtg ttgaaagaga
    18721 ttgaagaaaa tggcttcgtg actcgctttc ttcggtcttt ttcgttttat tatcaatttg
    18781 taaacgattt acaatttgag tcaaattatg gtaaaatagt gtcatgagta aaatgtatta
    18841 tgcagaaaat cctgacgctg ctcacgacat tcatgagttg agagtagagt tgttgggaca
    18901 aaaaatgacc tttttaacgg atgcgggtgt ttttagcaag aaaatagttg actttggaag
    18961 tcaactattg ctcaagtgtc ttgaggtcaa ccaaggagaa actgtccttg atgtaggctg
    19021 tggttacgga cctttgggtt tgtccttagc taaggcttat ggagttcagg ctactatggt
    19081 tgatatcaac actcgtgcct tagatttagc tcggagaaat gctgaaaaaa ataatgcaaa
    19141 agcgacgatt ttccagtcca acatctatga acaagttgaa ggacattttg atcatgtcat
    19201 ttccaatcct cctatccgtg cgggcaagca agtcgttcat gaaatcattg agaaaagtaa
    19261 agatttcttg gaaactggtg gggatttgac aatcgtcatc cagaaaaaac aaggggctcc
    19321 aagtgctaag tccaagatgg aggatgtgtt tggtaattgt gaaatcctta aaaaagacaa
    19381 aggatactat atccttagaa gtgtgaaaga atgagagcag ttgatttaat ccaaaaaaaa
    19441 cgagacggtc aagaactgac ttcaagtgaa attgaatggc tgatagaagg ctatgtatca
    19501 ggaactgttc ctgattatca gatgtctgcc tttgctatgg ctgtttattt taaaggaatg
    19561 acgactcgag aaatctctga tttaacgatg aatatggtta agactgggca agagtttgac
    19621 ctgtcagcca ttgatggtgt gaaagttgac aagcattcta ctggtggtgt cggcgataag
    19681 gtaaccttga ttttagctcc tcttgttgct agcttcggtg tgcctgtagc aaaaatgagt
    19741 ggtcgtggtc ttggccatac aggcggaaca attgataaat tggagtccat taggggctat
    19801 caagtagaac gtagtcaaga ggattttatt cgtcaggttc aggatattgg agtatctgtc
    19861 attgggcaat cagaccagct ggtcaaagca gataagcttc tctatgccct tcgtgatgtg
    19921 accgcaactg tcgacacgat tcctttgatt gcgagttcgg tgatgagcaa gaaaatcgcg
    19981 gcaggggcgg atgctatttt gctagacgtg actgtcggtg agggtgcctt catgaagacg
    20041 gttgatgagg cgcgtgagtt ggctcaaact atggtagatc ttggtaaggt tgttggacgg
    20101 aagacagtag cagtgattac ggatatgagc cagcctttgg gacgagcgat tggaaatcgt
    20161 ctggaaatcc ttgaagcatt ggagattttg caaggtcaag gacgtcagga tattacccac
    20221 tttatttgtg aattggctca aattatgctt ggcttggcaa atgttaacaa gactgttgaa
    20281 gaagttcgcc aacatcttga ggatggtcaa gcactggcta agtttgagga aatggtgcaa
    20341 gcccaaggtg gagacttgga agacctctat cgtcctgtaa atgtagctca tgtggtggaa
    20401 atccctgctc aggaaacagg tgtcatttca gctcttccag ctatggactt tggtctttat
    20461 gccatgaggc tgggtgctgg tcgtgcagtt aagtctgatg ccttggacta tgaaacagga
    20521 attgtttttg aaaagaagat tggagactcc gttcaaaagg gtgaaattgt tgcaaaagta
    20581 tacacaaatg aaaaaattcc acctcaacta gttacagatt tccaaaaatg tgttaaaata
    20641 agtgatgaag tgaaaaaaat ccgtgaaatt gtagaaatca tctcctaaat ggagggaaaa
    20701 ccgaaatgaa attaaataaa tatatagatc atacgctttt aaaacaagat gcaaagaaaa
    20761 aacaaattga tagtttgttg tctgaggcta gagagtatgg ctttgccagt gtttgcgtta
    20821 atccaacctg ggttgaacat gctaaaaaag ggcttgaagg cacagatgtt aaggtttgca
    20881 cggtagtagg tttccctttg ggagcaacaa cttcagccgt gaaagcattt gagacaaaag
    20941 aagctatcca aaatggtgca gatgagattg atatggtgat caatgttgga gctctcaaat
    21001 caggtaattt agccttggtt gagtcagata ttcgcgcagt agtggaagca agtggtgata
    21061 agttagtgaa agtcattatt gaagcttgcc ttctgacaga ccaagaaaaa gttgttgttt
    21121 gccaattggc ccaaaaagct ggggctgact ttgtcaaaac atctactggc ttttcaactg
    21181 gtggtgctac gatagcagat gttacattaa tgcgtgaaac agttggatct gatatgggag
    21241 tcaaggctgc tggtggagct cgttcttatg cagatgctct tgcctttgtc gaagcaggtg
    21301 cgacccgtat cggaacgtca gctggggtag ctattttaaa aggagaattg gcagatggcg
    21361 actactgagt tgattgaact ggcaattgaa accagcaaac atgcctatgt cccctattct
    21421 cactttccta tcggagcagt tttagtagcc aaagacggaa atgtttacac gggagtgaat
    21481 atcgaaaatg ctagctatcc tttgaccaat tgcggtgaga gaacagctat ttttaaggct
    21541 atatctgaag gccaaagaga attttcagaa ttgattgtct atggtcaaac tgaaaaaccg
    21601 atttcaccat gtggtgcttg tcgccaagta atggtcgaat tttttgaaca agatttaaaa
    21661 gtgaccttag tcgcaaaaga taaatcgacg gtcgagatga cggtcgggga gttacttcca
    21721 tattctttta cagacttaaa ttagtctgag tcgctctttg agtggcaagg gtctttgtga
    21781 ccaatcaatc catacttgca acatcgttgc acatcttatt taggaggttc agtaatgaac
    21841 aagaaacaat ggctaggtct tggcctagtt gcagtggcag cagttggact tgctgcatgt
    21901 ggtaaccgct cttctcgtaa cgcagcttca tcttctgatg tgaagacaaa agcagcaatc
    21961 gtcactgata ctggtggtgt tgatgacaaa tcattcaacc aatcagcttg ggaaggtttg
    22021 caggcttggg gtaaagaaca caatctttca aaagataacg gtttcactta cttccaatca
    22081 acaagtgaag ctgactacgc taacaacttg caacaagcgg ctggaagtta caacctaatc
    22141 tttggtgttg gttttgccct tcacaatgca gttgaagaag cagctaaaga acacactgac
    22201 ttgaactatg tcttgattga tgatgtgatt aaagaccaaa agaatgttgc gagcgtaact
    22261 ttcgctgata atgagtcagg ttaccttgca ggtgtggctg cagcaaaaac aactaagaca
    22321 aaacaagttg gttttgtagg tggtatcgaa tctgaagtta tctctcgttt tgaagcagga
    22381 ttcaaggctg gtgttgcgtc agtagaccca tctatcaaag tccaagttga ctacgctggt
    22441 tcatttggtg atgcggctaa aggtaaaaca attgcagccg cacaatacgc agccggtgca
    22501 gatattgttt accaagtagc tggtggtaca ggtgcaggtg tctttgcaga ggcaaaatct
    22561 ctcaacgaaa gccgtcctga aaatgaaaaa gtttgggtta tcggtgttga ccgtgaccaa
    22621 gaagcagaag gtaaatacac ttctaaagat ggcaaagaat caaactttgt tcttgtatct
    22681 actttgaaac aagttggtac aactgtaaaa gatatttcta acaaggcaga aaaaggagaa
    22741 ttccctggcg gtcaagtgat cgtttactca ttgaaggata aaggggttga cttggcagta
    22801 acaaaccttt cagaagaagg taaaaaagct gtcgaagatg caaaagctaa aatccttgat
    22861 ggaagcgtaa aagttcctga aaaataatgg atggaagtca tttcttagga agcggccaag
    22921 ggccgctttt ttaagagttg agacaaagtc attttgtctc agtaaagctt gctactagac
    22981 aaactagcaa gttttattga aataaaataa gactctgaaa ggaagagcac atggcacacg
    23041 aaaatgtcat tgagatgcgt gatattacca aggtgtttgg tggatttatt gccaacgaca
    23101 aaatcaactt gcacctacga aaaggtgaaa ttcatgcact tttaggagaa aatggggctg
    23161 gtaagtccac gctaatgaac atgttagcag gccttcttga accaactagt ggtgaaatcg
    23221 cggtcaacgg tcaagttgtc aatctcgact ccccatctaa agcagctagc ttgggaatcg
    23281 ggatggttca ccagcacttt atgttggttg aagccttcac agtggctgaa aacatcattt
    23341 taggtagtga attgactaaa aatggtgtgc tagatatcgc tggagctagc aaagaaatca
    23401 aggctctttc tgaacgttat ggcttagctg ttgacccttc tgccaaggta gcagatatct
    23461 cagttggagc ccaacaacgt gtagaaattt taaaaacact ttataggggg gctgatatcc
    23521 ttatctttga cgaaccaacg gctgttttga ctccatcaga aattgatgag ttgatggcta
    23581 ttatgaaaaa tcttgtcaaa gaaggaaaat caattatctt gattacccac aaattggatg
    23641 aaattcgcgc agtttctgac cgtgttacag ttatccatcg tgggaaatca attgaaaccg
    23701 ttgaaattgc aggggctacc aatgctgatt tggcggaaat gatggtagga cgttctgttt
    23761 cctttaaaac agagaagcaa gcctctaaac caaaagaagt ggttttgtct atcaaagatt
    23821 tggtggtcaa tgaaaaccgt ggtgttccag ctgttaaaaa tctgtccttg gatgttcgtg
    23881 ctggagagat tgttggtatt gcggggattg atggaaatgg tcagtctgaa ctgattcaag
    23941 ccattacagg tcttcgtaag gttgaatctg gtagcattga gctaaaagga gattcaattg
    24001 taggcttgca cccacgtcag attacagaac taagtgttgg gcacgttcca gaagaccgtc
    24061 accgtgatgg cttgattttg gaaatgatga tatctgaaaa tattgccctt caaacctact
    24121 ataaagaacc acatagtaaa aatggaattt tgaactattc aaatattact tcttatgcta
    24181 aaaagctgat ggaagagttt gatgttcgcg ctgccagtga attagttcct gcagctgcac
    24241 tctcaggagg aaatcaacaa aaagcaatta ttgctcgtga aattgatcga gatcctgatc
    24301 tccttatcgt tagccagcca actcgtgggt tggatgtcgg tgccattgag tatatccaca
    24361 aacgcttgat tgaagagcgt gataatggca aggctgtcct tgttgtcagc tttgaattgg
    24421 atgagatttt aaacgtctca gaccgtattg ccgttatcca cgatggtaag attcaaggta
    24481 ttgtatcacc agaaacaacc aataaacaag aacttggtgt cttgatggct ggtggaaact
    24541 tgggaaagga gaagagtgat gtctaaaaaa ttacaacaaa tttcggttcc cttgatttct
    24601 gtatttctag gaattttact cggagccatt gtcatgtgga tcttcggtta tgatgctatt
    24661 tggggctacg aagaattatt ctatacagcc tttggcagtc tgcgtgggat tggagaaatc
    24721 ttccgtgcta tgggtcctct ggtcttgatt ggtcttggtt ttgcggttgc cagtcgagct
    24781 ggtttcttta acgtcggact tcctggtcag gctttggcag gttggattct cagtggttgg
    24841 tttgcgctgt cgcatccaga tatgccccgt cccttgatga ttctagcaac catcgtgatt
    24901 gccttgattg ctggtgggat tgtcggagcg attccaggta ttcttagggc ctatctaggg
    24961 acgtcagagg ttattgtaac catcatgatg aactacattg tcttgtatgt agggaatgcc
    25021 tttatccatg ctttccctaa agacttcatg caaagtacag attcgaccat tcgtgttggg
    25081 gctaatgcaa cctatcagac accttggttg gctgagttga ctggtaactc acggatgaat
    25141 attggtattt tctttgccat cattgccgtt gcagttattt ggttcatgct caagaaaaca
    25201 actcttggtt ttgaaatccg tgcagttggt cttaatccac atgcttcaga atatgctggt
    25261 atttctgcca agcggactat tatcctatct atgattattt caggtgcctt ggcaggtctt
    25321 ggtggatctg ttgaaggttt gggaaccttc cagaacgtct atgttcaagg ttcgtcatta
    25381 gctatcggat ttaacggaat ggcggttagt ttgcttgcgg ccaactcacc aattggtata
    25441 ctctttgcag ccttcctatt tggcgttctc caagttgggg ctcctggtat gaatgcggcg
    25501 caggtaccat ctgagcttgt cagcattgta acagcgtcta ttatcttctt tgtcagtgtt
    25561 cattacctta tcgaacgctt tgtcaaaccg aaaaaacaag ttaaaggagg taagtaaaga
    25621 tgtctattat aaccttgctc cccctcttgg tgtcttctat gctgatttac tcagcacctc
    25681 tcatctttac aagtatcggt ggtgttttct ctgaacgtgg tggtgtggta aacgttggcc
    25741 ttgaaggaat tatggttatg ggtgcctttt ctggagttgt ctttaacctt gaatttgcag
    25801 aacaatttgg agcagcaact ccatggctat ccttgcttgt agcaggattg gttggtagtg
    25861 ttttctctat catccacgca gcagcgacgg ttcatttccg tgcagaccat gttgtcagcg
    25921 gtacggtatt gaacttgatg gcgcctgcct tggctgtttt cttagttaaa gttctttata
    25981 acaaaggaca aaccgacaac ctaagtcaaa cttttggacg ctttgatttc ccagtcttgg
    26041 caaatatccc agtgattggt gatatcttct tcaagtcaac tagtctactt ggttatctgg
    26101 cgattgcctt ctcattcctt gcttggttta ttctctttaa gactcaattt ggtcttcgtc
    26161 tccgctctgt cggtgaacat cctcaagcag cggatacctt gggaatcaac gtctacaaga
    26221 tgagatattt agggattatt atttcaggtt ttctaggtgg aattggcgga gcgatttatg
    26281 cgcaatcaat ctcagttaac ttctcagtga caactattgt tggacctgga tttatcgccc
    26341 ttgctgcgat gatctttggg aaatggaatc caatcggtgc tatgctttct agtctcttct
    26401 ttggactttc acaaagtttg gctgttatcg gttctcaatt gccgttccta caaggagtgc
    26461 cagcggttta tcttcaaatt gcaccttatg ttttgacaat tcttgtctta gcagccttct
    26521 ttggaaaagc agtcgcacca aaagcagatg gtatcaacta catcaaatca aaataagcat
    26581 acaaaaaaac gtcagtccaa tgactgaact gccccccaaa agttagacag aaaaaatcta
    26641 acttttgggg tgtttttatt atgaaactaa cttatgatga taaagttcag atctatgaac
    26701 ttagaaaaca aggatatagc ttagagaagc tttcaaataa atttgggata aacaattcta
    26761 atcttaggta catgattaaa ttgattgatc gttacggaat agagttcggc aaaaaaggaa
    26821 aaaatcgtta ctattctcct gatttaaaac aagaaatgat taataaagtc tgacatgaag
    26881 gctggactaa agatagagtt tctcttgaat actgtctccc aagtcgtacg atacttctta
    26941 actggctagc acaatacagg aaaaacgggt atactattgt tgagaaaaca agagggagag
    27001 tacctaaaat gggacgtaag ccaaaaaaga gacctgaaga gaggacagaa ttagaatatc
    27061 ttcaagcaga aaatgagtac ctgagagcgg agaatgccat cctaaaaaag ttaagagaac
    27121 tccgattgaa ggaggaaaaa gagaaagaag aaagacagaa attgttcaag aattaatgac
    27181 tgagttttcg ttagttcttc ttctaaaatc tattaaacta gctcgttgga cctactacta
    27241 tcacttgaaa cagctagaca aaacagataa ggaccaagag cttaaagctg aaattcaatc
    27301 catctttatc gaacacaaag gaaattatgc ttatcgccgg gttcatttag aactaagaaa
    27361 tcgtgcttat ctggtaaatc ataaaagagt tcaaggcttg ata
//
LOCUS       DAVLXH010000025        26979 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00028199
            SAMN33607166-rid17955573.denovo.025, whole genome shotgun sequence.
ACCESSION   DAVLXH010000025 DAVLXH010000000
VERSION     DAVLXH010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607166
            Sequence Read Archive: SRR23725544
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 26979)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26979)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721421.1
            Genome Coverage       :: 115x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:42:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,210
            CDSs (total)                      :: 2,161
            Genes (coding)                    :: 2,023
            CDSs (with protein)               :: 2,023
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 73 of 138
            Pseudo Genes (incomplete)         :: 60 of 138
            Pseudo Genes (internal stop)      :: 40 of 138
            Pseudo Genes (multiple problems)  :: 31 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26979
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607166-rid17955573.denovo.025"
                     /strain="AUSMDU00028199"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1349"
     gene            <1..534
                     /locus_tag="VYO11_001177"
     CDS             <1..534
                     /locus_tag="VYO11_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding SSURE repeat-containing
                     protein"
                     /protein_id="HEV1595754.1"
                     /translation="ENVKTKGQYFYQLALDGNVAGKEKQALIDQFRANGTQTYSATVN
                     VYGNKDGKPDLDNIVATKKVTIKINVKETSDTANGSLSPSNSGSGVTPMNHNHATGTT
                     DSMPADTMTSSTNTMAGENMAASANKMSDTMMSEDKAMLPNTGETQTSMASIGFLGLA
                     LAGLLGGLGLKNKKEEN"
     gene            701..1399
                     /locus_tag="VYO11_001178"
     CDS             701..1399
                     /locus_tag="VYO11_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000520636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1595755.1"
                     /translation="MGKTILLVDDEVEITDIHQRYLIQAGYQVLVAHDGLEALELFKK
                     KPIDLIITDVMMPRMDGYDLISEVQYLSPEQPFLFITAKTSEQDKIYGLSLGADDFIA
                     KPFSPRELVLRVHNILRRLHRGGETELISLGNLKMNHSSHEVQIGEEMLDLTVKSFEL
                     LWILASNPERVFSKTDLYEKIWKEDYVDDTNTLNVHIHALRQELAKYSSDQTPTIKTV
                     WGLGYKIEKPRGQT"
     gene            1396..2448
                     /locus_tag="VYO11_001179"
     CDS             1396..2448
                     /locus_tag="VYO11_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000769768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEV1595756.1"
                     /translation="MKLKSYILVGYIISILLTILVVFWAVQKMLIAKGEIYFLLGMTI
                     VASLVGAGISLFLLLPVFTSLGKLKEHAKRVAAKDFPSNLEVQGPVEFQQLGQTFNEM
                     SHDLQVSFDSLEESEREKGLMIAQLSHDIKTPITSIQATVEGILDGIIKESEQAHYLA
                     TIGRQTERLNKLVEELNFLTLNTARNQVETTSKDSIFLDKLLIECMSEFQFLIEQERR
                     DVHLQVIPESARIEGDYAKLSRILVNLVDNAFKYSAPGTKLEVVAKLEKDQLSISVTD
                     EGQGIAPEDLENIFKRLYRVETSRNMKTGGHGLGLAIARELAHQLGGEITVSSQYGLG
                     STFTLVLNLSGSENKA"
     gene            2643..3254
                     /gene="rpsD"
                     /locus_tag="VYO11_001180"
     CDS             2643..3254
                     /gene="rpsD"
                     /locus_tag="VYO11_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HEV1595757.1"
                     /translation="MSRYTGPSWKQARRLGLSLTGTGKELARRNYVPGQHGPNNRSKL
                     SEYGLQLAEKQKLRFTYGVGEKQFRNLFVQATKIKGGILGFNFMLLLERRLDNVVYRL
                     GLATTRRQARQFVNHGHILVDGKRVDIPSYRVTPGQVISVREKSLKVPAILEAVEATL
                     GRPAFVSFDAEKLEGSLTRLPERDEINPEINEALVVEFYNKML"
     gene            3431..3586
                     /locus_tag="VYO11_001181"
                     /pseudo
     CDS             3431..3586
                     /locus_tag="VYO11_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            3917..4177
                     /locus_tag="VYO11_001182"
     CDS             3917..4177
                     /locus_tag="VYO11_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1595758.1"
                     /translation="MTGVSNPTTDSARLVLAEAKKALADDSLTEQGLRDILQTVKDAI
                     ASLESIKESQSATKDGGQTAGKETAGEDESANQTQEISQGIK"
     gene            4131..4352
                     /locus_tag="VYO11_001183"
     CDS             4131..4352
                     /locus_tag="VYO11_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1595759.1"
                     /translation="MSLQIKLKKLAKELSKLLKDSNLETVDKDVLENSQEELQKAVLF
                     LADEKGSEHTEAELIDNLKEVIAKLKANA"
     gene            4671..5600
                     /locus_tag="VYO11_001184"
     CDS             4671..5600
                     /locus_tag="VYO11_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV1595760.1"
                     /translation="MKKFSKTLRDNWIFLLMVLPGALWLILFFYIPVFGNVVAFKDYH
                     MTSNGFIDSIINSKWVGLDNFRFLFSSRDAFIITRNTVLYNLGFIFLGLVVSVGIAII
                     LSELRSKRMVKIFQTSMLFPYFLSWVIISFFTDAFLNIDKGVFNHLLESLGLKEVNFY
                     ADLGIWPYLLLFLGIWKGFGYSSVMYYATIMGIDPTYYEAATVDGASKWQRIRNVTIP
                     QLTPLVTVLTILAVGNIFRADFGLFYQIPHNAGQLYNVTNVLDVYVFNGLTQTADIGM
                     AAAAGLYQSVVGLILVILSNLLARRVDPNSALF"
     gene            5614..6537
                     /locus_tag="VYO11_001185"
     CDS             5614..6537
                     /locus_tag="VYO11_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001075101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEV1595761.1"
                     /translation="MAKKKIKKEKIDNVGIHSFSKKADIFFSIISGLIALSCILPFVF
                     VIIISVTDEKSLLQYGYSFFPSQFGLDGFEFLAQFKDKILQALFISVFVTVVGTLTNV
                     FITTTYAYAISRTTFKYRRFFTIFVLLSMLFNAGLVPGYIMVTRVLQLGDTVWALIVP
                     MLLSPFNIILMRSFFKKTIPEAILESARIDGASEARIFFQICLPLSLPGIATITLLTA
                     LGFWNDWFNALLYIKSDNLYPLQYLLMQIQQNMDYIAKAVGLTGQLGVALPKETGRMA
                     MVVVATLPIAILYPFFQRYFVKGLTIGGVKE"
     gene            6795..8270
                     /locus_tag="VYO11_001186"
     CDS             6795..8270
                     /locus_tag="VYO11_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3502 domain-containing protein"
                     /protein_id="HEV1595762.1"
                     /translation="MKNWKKYAFASASVVALAAGLAACGNLTGNSKKAADSGDKPVIK
                     MYQIGDKPDNLDELLANANKIIEEKVGAKLDIQYLGWGDYGKKMSVITSSGENYDIAF
                     ADNYIVNAQKGAYADLTELYKKEGKDLYKALDPAYIKGNTVNGKIYAVPVAANVASSQ
                     NFAFNGTLLAKYGIDISGVTSYETLEPVLKQIKEKAPDVVPFAIGKVFIPSDNFDYPV
                     ANGLPFVIDLEGDTTKVVNRYEVPRFKEHLKTLHKFYEAGYIPKDVATSDTSFDLQQD
                     TWFVREETVGPADYGNSLLSRVANKDIQIKPITNFIKKNQTTQVANFVISNNSKNKEK
                     SMEILNLLNTNPELLNGLVYGPEGKNWEKIEGKENRVRVLDGYKGNTHMGGWNTGNNW
                     ILYINENVTDQQIENSKKELAEAKESPALGFIFNTDNVKSEISAIANTMQQFDTAINT
                     GTVDPDKAIPELMEKLKSEGAYEKVLNEMQKQYDEFLKNKK"
     gene            8542..9528
                     /locus_tag="VYO11_001187"
     CDS             8542..9528
                     /locus_tag="VYO11_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HEV1595763.1"
                     /translation="MAKDIRVLLYYLYTPIENAEQFAADHLAFCKSIGLKGRILVADE
                     GINGTVSGDYETTQKYMDYVHSLPGMEDLWFKIDEESEQAFKKMFVRYKKEIVHLGLE
                     DNDFDNDINPLETTGAYLSPKEFKEALLDKDTVVLDTRNDYEYDLGHFRGAIRPDIRN
                     FRELPQWVRDNKEKFMDKRVVVYCTGGVRCEKFSGWMVREGYKDVGQLHGGIATYGKD
                     PEVQGELWDGKMYVFDERIAVDVNHVNPTIVGKDWFDGTPCERYVNCGNPFCNRRILT
                     SEENEDKYLRGCSHECRVHPRNRYVSKNELTQAEVIERLAAIGESLDQAATV"
     gene            9803..10649
                     /locus_tag="VYO11_001188"
                     /pseudo
     CDS             9803..10649
                     /locus_tag="VYO11_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140341.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4299 domain-containing protein"
     gene            complement(10720..11784)
                     /locus_tag="VYO11_001189"
     CDS             complement(10720..11784)
                     /locus_tag="VYO11_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1595764.1"
                     /translation="MKQEWFESNDFVKTTSKNKPEEQAQEVADKAEETIADLDTPIGK
                     NTQVEEEVSQAEVELESQQEEKIETPEDSEARTEIEEKKASNSTEEEPDLSKETEKVT
                     IAEESQEALPQQKATTKEPLLISKSLESPYIPDQAPKSRDKWKEQVLDFWSWLVEAIK
                     SPTSKLETSITHSYTAFLLLILFSASSFFFSIYHIKHAYYGHIASINSRFPEQLAPLT
                     LFSIISILVATTLFFFSFLLGSFVVRRFIHQEKDWTLDKVLQQYSQLLAIPIFLTAIA
                     SFFAFFDSLRFTALLCVISIGIILLASLHIITRPSQASETDSFYQLFLSVLVNGVIIL
                     LFFVAEVALIGDYLRILAFL"
     gene            complement(11846..12757)
                     /locus_tag="VYO11_001190"
     CDS             complement(11846..12757)
                     /locus_tag="VYO11_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001233690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 domain-containing protein"
                     /protein_id="HEV1595765.1"
                     /translation="MRKWTKGFLIFGVVTTVIGFILLFVGIQSDGIKSLLSMSKEPVY
                     DSRTEKLTFGKEVENLEITLHQHTLTITDSFDDQIHISYHPSLSAHHDLITNQNDRTL
                     SLTDKKLSETPFLSSGIGGILHIASSYSSRFEEVILRLPKGRTLKGINISANRGQTTI
                     INASLENATLNTNSYILRIEGSRIKNSKLTTPNIVNIFDTVLTDSQLESTDNHFHAEN
                     IQVHGKVELTAKDYLRIILDQKENQRINWDISSNYGSIFQFTREKPESRGTELSNPYK
                     TEKTDVKDQLIARSDDNIDLISTPSRR"
     gene            complement(12750..13343)
                     /locus_tag="VYO11_001191"
     CDS             complement(12750..13343)
                     /locus_tag="VYO11_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000198695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HEV1595766.1"
                     /translation="MTRTEYLTQLELYLKKLPEADRIEAMDYFRELFDDAGVEGEEEL
                     IASLGTPKEAAHEVLSNLLDKKINEAPAQKNNRQILHIALLALLAAPIGIPLGIAILV
                     TLFAILVAALTVILAFFAVSILGIIGGFLFLVESFTILAQAKSAFILIFGSGLLAIGA
                     SSLVLLGISYVARFFGLLIVRLVQFVLKKGKRGNQHA"
     gene            complement(13330..13656)
                     /locus_tag="VYO11_001192"
     CDS             complement(13330..13656)
                     /locus_tag="VYO11_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HEV1595767.1"
                     /translation="MYFPTSSALIEFLILAVLEQGDSYGYEISQTIKLIANIKESTLY
                     PILKKLEGNSFLTTYSREFQGRMRKYYSLTNGGIEQLLTLKDEWALYTDTINGIIEGS
                     IRHDKN"
     gene            complement(13795..14961)
                     /locus_tag="VYO11_001193"
     CDS             complement(13795..14961)
                     /locus_tag="VYO11_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CynX/NimT family MFS transporter"
                     /protein_id="HEV1595768.1"
                     /translation="MKKQSLFFVPGIILIGVSLRTPFTVLPIILGNISQGLEVEVSSL
                     GVLTSLPLLMFTLFSPFSTRLAQKIGLEHLFTYSLFFLTIGSLIRLINLPLLYLGTLM
                     VGASVAVINVLLPSLIQANQPKKIGFLTTLYVTSMGIATALASYLAVPITQASSWKGL
                     ILLLTLLCLATFLVWLPNHRYNHRLAPQTKQKSQIKVMRNKQVWAIIIFSGFQSLIFY
                     TVMTWLPTMSIHAGLSSHEAGLLTSILSLISIPFSMTIPSLTTSLSTRNRQLMLTLVS
                     LAGVVGISMLFFPINNFIYWLAIHLLIGTATSALFPYLMVNFSLKTSAPEKTAQLSGL
                     SQTGGYILAAFGPTLFGYSFDLFHSWVPSVAALLLIDILMTVALFTVDRADKIL"
     gene            15019..16176
                     /locus_tag="VYO11_001194"
     CDS             15019..16176
                     /locus_tag="VYO11_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV1595769.1"
                     /translation="MSSKVSGFQDKNGKVLKIMIEWWKEKFRRVVVTQNVESLLVSIV
                     ISAYNEEKYLPGLIEDLKNQTYPKENIEILFINAMSTDGTTAIIQQFIKEDTEFNSIR
                     LYNNPKKNQASGFNLGVKHSVGDLILKIDAHSKVTESFVMNNVAIIQQGEFVCGGPRP
                     TIVEGKGKWAETLHLVEENMFGSSIANYRNSSEDRYVSSIFHGMYKREVFQKVGLVNE
                     QLGRTEDNDIHYRIREHGYKIRYSPSILSYQYIRPTFKKMLHQKYSNGLWIGLTSHVQ
                     FKCLSLFHYVPCLFVLSLVFSLALLPITFVFITLLLGAYFLLLSLLTLLTLLKHKNGF
                     LIVMPFLLFSIHFAYGLGTIVGLIRGFKWKKEYKRTIIYLDKISQINKNML"
     gene            16218..18068
                     /locus_tag="VYO11_001195"
     CDS             16218..18068
                     /locus_tag="VYO11_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HEV1595770.1"
                     /translation="MNKKLTDYVIDLVEILNKQQKQVFWGIFDIFSMVVSIIVSYILF
                     YGLINPAPVDYIIYTSLAFLFYQLMIGFWGLNASISRYSKITDFMKIFFGVTASSVLS
                     YSICYAFLPLFSIRFIILFILLSTFLILLPRITWQLIYSRRKKGSGDGEHRRTFLIGA
                     GDGGALFMDSYQHPTSELELVGILDKDSKKKGQKLGGIPVLGSYDNLPELAKRHQIER
                     VIVAIPSLDPSEYERILQMCNKLGVKCYKMPKVETVVQGLHQAGTGFQKIDITDLLGR
                     QEIRLDESRLGAELTGKTILVTGAGGSIGSEICRQVSRFNPERIVLLGHGENSIYLVY
                     HELIRKFQEIDYVPVIADIQDYDRLLQVFEQYKPAIVYHAAAHKHVPMMERNPKEAFK
                     NNIRGTYNVAKAVDEAKVSKMVMISTDKAVNPPNVMGATKRVAELIVTGFNQRSQSTY
                     CAVRFGNVLGSRGSVIPVFERQIAEGGPVTVTDFRMTRYFMTIPEASRLVIHAGAYAK
                     DGEVFILDMGKPVKIYDLAKKMVLLSGHTESEIPIVEVGIRPGEKLYEELLVSTELVD
                     NQVMDKIFVGKVNVMPLESINQKIGEFRTLSGDELKQAIIAFANQTTHIE"
     gene            complement(18250..18348)
                     /locus_tag="VYO11_001196"
                     /pseudo
     CDS             complement(18250..18348)
                     /locus_tag="VYO11_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(18374..19006)
                     /locus_tag="VYO11_001197"
     CDS             complement(18374..19006)
                     /locus_tag="VYO11_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000200889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEV1595771.1"
                     /translation="MTSITAIFFDLDGTLVDSSIGIHNAFTYTFKELGVPSPDAKTIR
                     GFMGPPLESSFATCLSKDQISEAMQIYRSYYKAKGIYEAQLFPQIIDLLEELSSSYPL
                     YITTTKNTSTAQDMAKNLEIHHFFDGIYGSSPEAPHKADVIHQALQTHQLAPEQAIII
                     GDTKFDMLGARETGIQKLAVTWGFGEQADLLNYQPDYIAHKPLEVLAYFQ"
     gene            complement(19028..19900)
                     /gene="sdaAA"
                     /locus_tag="VYO11_001198"
     CDS             complement(19028..19900)
                     /gene="sdaAA"
                     /locus_tag="VYO11_001198"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HEV1595772.1"
                     /translation="MFYSIKELVEQADLDFQGNVAELMITTEFELTGREREEVFLLME
                     RNLEVMKASVQLGLNENKSRSGLTGGDAAKLDHYIKNEKTLSDYTILSAARNAIAVNE
                     HNAKMGLVCATPTAGSAGCLPSVLTAAIEKLDLSHEQQLDFLFAAGAFGLVIANNASI
                     SGAEGGCQAEVGSASAMSAAALTLAAGGTPYQASQAIAFVIKNMLGLICDPVAGLVEV
                     PCVKRNAMGASFAFIAADMALAGIESKIPVDEVIDAMYQVGASMPTAFRETAEGGLAT
                     TPTGRRLQKEIFGE"
     gene            complement(19909..20580)
                     /gene="sdaAB"
                     /locus_tag="VYO11_001199"
     CDS             complement(19909..20580)
                     /gene="sdaAB"
                     /locus_tag="VYO11_001199"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015606087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HEV1595773.1"
                     /translation="MKSLRFQSVFDIIGPVMIGPSSSHTAGAVRIGKIVSSIFDDTPT
                     EVEFQLFNSFAKTYRGHGTDLALVAGILGMDTDDPEIPNSLEIAHKRGIKIVWTIQKD
                     SNAPHPNTTKITVKNAHKTISVTGISIGGGNIQVTELNGFAVSLNMNTPTIIIVHQDI
                     PGMIALVTEALSRYGINIAQMNVTREKAGEKAIMIIEVDSRNCDEAIEEIRKIPHLHN
                     VNFFK"
     gene            20822..21394
                     /locus_tag="VYO11_001200"
     CDS             20822..21394
                     /locus_tag="VYO11_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEV1595774.1"
                     /translation="MKSITKKIKATLAGVAALFAVFAPSFVSAQESSTYTVKEGDTLS
                     EIAETHNTTVEKLAENNHIDNIHLIYVDQELVIDGPVAPVATPAPATYAAPAAQDETV
                     SAPVVSETVVSTVSGSEAEAKEWIAQKESGGSYTATNGRYIGRYQLTDSYLNGDYSAE
                     NQERVADAYVAGRYGSWTAAKNFWLNNGWY"
     gene            complement(21447..21767)
                     /locus_tag="VYO11_001201"
     CDS             complement(21447..21767)
                     /locus_tag="VYO11_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEV1595775.1"
                     /translation="MQRLEVYKNYQHLYDLRIAILLNLSTLYLYNQDKNMCKQICYTL
                     LEDAKNKKSYDRLAICYVRIGICTDNAKLIQKGFSLLELTEETSMLSHLKKEVETHYQ
                     PKKL"
     gene            22192..22479
                     /locus_tag="VYO11_001202"
     CDS             22192..22479
                     /locus_tag="VYO11_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001230165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HEV1595776.1"
                     /translation="MRKLVKIGVASLMVCGILATTNALAVWVEGGQWNYGVGWTGTFG
                     YSDYLHSTRYHTATVRHGGRTSKDYAKPEAWARASLTKIPPTGMEYFYGFE"
     gene            22531..24639
                     /locus_tag="VYO11_001203"
     CDS             22531..24639
                     /locus_tag="VYO11_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000723955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEV1595777.1"
                     /translation="MKKISNFCMLLLLLCTTFFVFNVNYTREVVRIQEMGKTVDSLDL
                     YLKDINEPAASVLRFFEDVSKEYKVSIIKTDSGDEVVKSGVFDKDTFPYQEFGISSLD
                     FTTDGEGVYSNKEISNKLGTIPTFLKAKPIQLMTFQTYIKDTSRSLNGRYTITSTQEM
                     DKDRIVQKWSDFFKIDQATLLEPTYKSAVEVINRDLLLSAIVFVLAILLLVLVTVYQP
                     MMEMKRVGVQKLLGFQDRAVLADVVKGNLYLLLGGALVINLGVFFLLDYKPKDLFPML
                     WLSHFLLLQLYLFISWLTYLLIQKMTISSLLKGFSSFKFGLIFNYVMKIGTTILLTAL
                     LIGVGRSLEQENKELAYQQQWVSQGNYLTLETFKLNDNLWQEELAGSGKSTDYFYRFY
                     QDLVEKTQAGYVQSSSLPVKNFVQSEQIQQYQLTDTVDVYYANRNFLKSKGFKLPDTG
                     IKKVILMPASTKGEEDKNQLLGKLIAFHSMKYEEQQKRTIEEMDVEIAYYEGDWSFFP
                     YSDKRKENLSNPIISLVNDSDMMWDEKASLSTTGLNNPIKIENTVQHQKEITELVEKL
                     SDGNYLKFSSIQAIQQEKVDSYRDAVRNFNLLFALFGLLSMMISYFLLVTTFLLKRRD
                     IITKKFMGWKLVDRYRPLLVLLLLGYSFPLLVLIFFAHAFLPLLLFAGFTCLDILFVL
                     GLASRMEKRSLVELLKGGIL"
     gene            24636..25277
                     /locus_tag="VYO11_001204"
     CDS             24636..25277
                     /locus_tag="VYO11_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1595778.1"
                     /translation="MIELKNITKTIGGKVILDNLSLRIDQGDLVAIVGKSGSGKSTLL
                     NLLGLIDGDYSGRYEIFGQTNLAVNSAKSQTIIREHISYLFQNFALIDDETVEYNLML
                     ALKYVKLPKKDKLKKVEEILERVGLSATLHQRVSELSGGEQQRIAVARAILKPSQLIL
                     ADEPTGSLDPENRDLVLKFLLEMNREGKTVIIVTHDAYVAQQCHRIIELGEGK"
     gene            25484..26290
                     /locus_tag="VYO11_001205"
     CDS             25484..26290
                     /locus_tag="VYO11_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001038484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEV1595779.1"
                     /translation="MNKMKKVLMTMFGLVMLPLLFACSNNQSAGIEAIKSKGKLVVAL
                     NPDFAPFEYQKVVDGKNQIVGSDIELAKAIATELGVELELSPMSFDNVLASVQSGKAD
                     LAISGVSKTDERSKVFDFSTPYYTAKNKLIVKKSDLATYQSVNDLAQKKVGAQKGSIQ
                     ETMAKDLLQNSSLVSLPKNGNLITDLKSGQVDAVIFEEPVAKGFVENNPDLAIADLNF
                     EKEQDDSYAVAMKKDSKELKEAVDKTIQKLKESGELDKLIEDAFKASIEK"
     gene            26307..26699
                     /locus_tag="VYO11_001206"
                     /pseudo
     CDS             26307..26699
                     /locus_tag="VYO11_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269502.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate synthase"
BASE COUNT         8186 a         4928 c         5852 g         8013 t
ORIGIN      
        1 gaaaacgtga agaccaaagg tcaatacttc tatcaattag ccttggacgg aaatgtagct
       61 ggcaaagaaa aacaagcgct cattgaccag ttccgagcaa acggtactca aacttacagc
      121 gctacagtca atgtctatgg taacaaagac ggtaaaccag acttggacaa catcgtagca
      181 actaaaaaag tcactattaa gataaatgtt aaagaaacat cagacacagc aaatggttca
      241 ttatcacctt ctaactctgg ttctggcgtg actccgatga atcacaatca tgctacaggt
      301 actacagata gcatgcctgc tgacaccatg acaagttcta ccaacacgat ggcaggtgaa
      361 aacatggctg cttctgctaa caagatgtct gatacgatga tgtcagagga taaagctatg
      421 ctaccaaata ctggtgagac tcaaacatca atggcaagta ttggtttcct tgggcttgcg
      481 cttgcaggtt tactcggtgg tctaggtttg aaaaacaaaa aagaagaaaa ctaatcagct
      541 aaggaaataa atgatggata gtgggctgac taagattagt ttaacaactc aatcagcaat
      601 caggactttc tttcaatagc agattaaaat catcgtaaaa caataaaaat agtgttatac
      661 ttaaagcagt atagcactgt ttttatcaaa ggagagacag atgggaaaga caattttact
      721 cgttgacgac gaggtagaaa tcacagatat tcatcagaga tacttaattc aggcaggtta
      781 tcaggtcttg gtagcccatg atggactgga agcgctagag ctgttcaaga aaaaaccgat
      841 tgatttgatt atcacagatg tcatgatgcc tcggatggat ggttatgatt taatcagtga
      901 ggttcaatac ttatcaccag agcagccttt cctatttatt actgctaaga ccagtgaaca
      961 ggacaagatt tacggcctga gcttgggagc agatgatttt attgctaagc cttttagccc
     1021 acgtgagctg gttttgcgtg tccacaatat tttgcgccgc cttcatcgtg ggggcgaaac
     1081 agagctgatt tcccttggca atctaaaaat gaatcatagt agtcatgaag ttcaaatagg
     1141 agaagaaatg ctggatttaa ctgttaaatc atttgaattg ctgtggattt tagctagcaa
     1201 tccagagcga gttttctcca agacagacct ctatgaaaag atctggaaag aagactacgt
     1261 ggatgacacc aataccttga atgtgcatat ccatgctctt cgacaggagc tggcaaaata
     1321 tagtagtgac caaacgccca ctattaagac agtttggggg ttgggatata agatagagaa
     1381 accgagagga caaacatgaa actaaaaagt tatattttgg ttggatatat tatttcaatc
     1441 ctcttaacca ttttggttgt tttttgggct gttcaaaaaa tgctgattgc gaaaggcgag
     1501 atttactttt tgcttgggat gaccatcgtt gccagccttg tcggtgctgg gattagtctc
     1561 tttctcctat tgccagtctt tacgtcgttg ggcaaactca aggagcatgc caagcgggta
     1621 gcggccaagg attttccttc aaatttggag gttcaaggtc ctgtagaatt tcagcaatta
     1681 gggcaaactt ttaatgagat gtcccatgat ttgcaggtaa gctttgattc cttggaagaa
     1741 agcgaacgag aaaagggctt gatgattgcc cagttgtcgc atgatattaa gacccctatc
     1801 acttcgattc aagcgacggt agaagggatt ttggatggga ttatcaagga gtcggagcaa
     1861 gctcattatc tagcaaccat tggacgccag acggagaggc tcaataaact ggttgaggag
     1921 ttgaattttt tgaccctaaa cacagctaga aatcaggtgg aaactaccag taaagacagt
     1981 atttttctgg acaagctctt aattgagtgc atgagtgaat ttcagttttt gattgagcag
     2041 gagagaagag atgtccactt gcaggtaatc ccagagtctg cccggattga gggagattat
     2101 gctaagcttt ctcgtatctt ggtgaatctg gtcgataacg cttttaaata ttctgctcca
     2161 ggaaccaagc tggaagtggt ggctaagctg gagaaggacc agctttcaat cagtgtgacc
     2221 gatgaagggc agggtattgc cccagaggat ttggaaaata ttttcaaacg tctttatcgt
     2281 gtcgaaactt cgcgtaacat gaagacaggt ggtcatggat taggacttgc gattgcgcgt
     2341 gaattggccc atcaattggg tggggaaatc acagtcagca gccagtacgg tctaggaagt
     2401 acctttaccc tcgttctcaa cctctctggt agtgaaaata aagcctaaaa cccctttaca
     2461 aatccagcta ttcatggtag aatagatttt gtgtgaaata tcagcaggaa agcatgaagc
     2521 tcgtcaacag gtgtcttatg acaagtaacc ttggctgttt aggcgaaggg catctgcacg
     2581 aatcagggct ttctaagtga ctatttccac cgaaatatta tttatatcag gaggacattc
     2641 atatgtcacg ttatacagga ccatcttgga aacaagctcg tcgccttggc ctttcactta
     2701 caggtacagg taaagaattg gcacgtcgta actacgtacc aggacaacac ggaccaaaca
     2761 accgttctaa attgtcagaa tacggtttgc aattggctga aaaacaaaaa cttcgtttca
     2821 cttacggtgt aggtgaaaaa caattccgta acttgttcgt acaagctaca aaaatcaaag
     2881 gcggaatcct aggtttcaac tttatgcttc ttttggaacg tcgtttggat aacgttgttt
     2941 accgtcttgg tctcgcgact actcgtcgtc aagctcgtca attcgtaaac cacggtcaca
     3001 tccttgttga cgggaaacgc gttgatatcc catcataccg cgtaactcca ggtcaagtga
     3061 tctcagttcg tgaaaaatca ttgaaagttc cagcaatcct tgaagcagta gaagctactc
     3121 ttggacgtcc agcattcgta tcattcgacg ctgaaaaatt ggaaggttca ttgactcgct
     3181 tgccagaacg cgacgaaatc aacccagaaa tcaacgaagc acttgtcgtt gaattctaca
     3241 acaaaatgtt gtaatatttt attgaataag ataggctttg atattaagca ctttgggacg
     3301 ttctccctta gtgctttttt gatttctctt agtatccagc tataatcgtt tagacataac
     3361 tagaccgata tagtccaaag tgatatagta aaatgaacca aaaatagtac acaatgtggt
     3421 ataatctttt atggcatatt caatagattt tcgtaaaaaa gttctctctt attgtgagcg
     3481 aacaggtagt ataacagaag catcacacgt tttccaaatc tcacgtaata ccatttatgg
     3541 ctggttaaag ctaaaagaga aaacaggaga gctaaaccac caagtatagt gtattgaatc
     3601 tataacagta caccttggct gctaaaatat ttctataaat taatttgact ttcctgatag
     3661 agttgttcac atcttatttc aaactactat aaaagttcta taatctcttt ataagatttg
     3721 ccctgttctt gtttcatttt actatagaac gatttgaagg cgtttatgat atttagctgt
     3781 acgagagtct tttaaaagtg ttttgatggt ttggatttct tctttagttg atttcatatc
     3841 actgttatgt aatgcttttt gattttagtc tagtattagt aagcagactc aaaccttaga
     3901 aaatcttttg agatcattga caggtgtatc gaatcctacc acagattcag cacgtctggt
     3961 tttggcagag gctaagaaag ctcttgcaga tgatagtttg acagagcaag gtttacgtga
     4021 tatcttgcaa acagtcaaag atgccattgc ttccctagag tccattaagg aaagccagtc
     4081 agcaactaag gatggaggac aaacagcggg caaagaaaca gcaggagaag atgagtctgc
     4141 aaatcaaact caagaaatta gccaaggaat taagtaaact tcttaaagac tcaaaccttg
     4201 aaacagtaga taaggatgtc cttgaaaact ctcaagaaga acttcaaaaa gcagttttgt
     4261 tcttggcaga tgaaaaaggc tctgagcata ctgaagcaga gttgattgat aatcttaaag
     4321 aggttattgc taagttgaaa gcaaacgcct aataacatat taaaaatctc cagattagga
     4381 actatcgctg agttccctag tctggagatt tttcagtata ccccgttgtt ggatgcttat
     4441 aacagagtga cgccatcact gggctaatag agataaaata aacaattgat ttaggacatt
     4501 tgttttatag tggtgataaa gttttaaatc tgctacataa tttgtggagt tttttctata
     4561 attaggagtt taacctaacc tgcaaatagg agtatactaa taatgtaatc gttatcaaaa
     4621 gtctaaaaaa gaatttttag atggatatca aaataaaaag ggaggaaatt atgaaaaagt
     4681 tttcaaaaac attgagagac aactggatct ttctcttgat ggttttgcca ggggcactct
     4741 ggttgattct attcttttac attccagtat ttgggaacgt ggttgccttc aaagactacc
     4801 acatgaccag taatggtttc atagatagta tcataaatag taaatgggtc ggactcgata
     4861 atttcagatt cttatttagt tcaagagacg cctttattat cacacgaaat actgtcctct
     4921 acaatcttgg ctttatcttt ctaggtttag ttgtatctgt agggattgcc attatcctca
     4981 gcgagctccg ttctaagaga atggtgaaga ttttccaaac ttctatgttg ttcccttact
     5041 tcttgtcttg ggttatcatc agtttcttta cagatgcctt cctaaatatt gataaagggg
     5101 tgttcaatca tctattggaa agtcttggtc tcaaagaagt caatttctac gctgacctgg
     5161 gcatctggcc ctatctccta cttttcctag gtatttggaa aggttttgga tatagcagtg
     5221 tcatgtacta tgcgacgatc atgggaattg atccaaccta ctacgaagca gcgacagtgg
     5281 acggagctag caagtggcaa cgtattcgca acgtaaccat tcctcagttg actccgcttg
     5341 taactgtatt gaccatcctt gcagtcggaa atatcttccg cgcagacttc ggtctcttct
     5401 atcaaatccc acacaatgct ggtcagcttt acaatgtaac caacgttttg gacgtatatg
     5461 tttttaatgg tttgactcag acagcagata tcggtatggc tgcagcagcc ggtctttacc
     5521 aatccgttgt tggtttgatt ctggttatcc tatcaaactt gcttgcaaga cgagtcgatc
     5581 caaactcagc tttgttctag aaaggaggag aatatggcaa aaaagaaaat taaaaaagaa
     5641 aaaattgata atgtcggcat tcactccttc agtaagaaag cagatatctt cttcagtatc
     5701 atttcgggtt tgattgccct ctcttgtatc ctaccttttg tattcgttat cattatttca
     5761 gtgacagacg agaaaagcct cctccaatac ggctatagct tcttcccatc ccaatttggc
     5821 ttagacggtt ttgagttttt ggcacagttt aaggataaaa tcctacaagc cctcttcatc
     5881 tctgtctttg taaccgtagt tgggacattg acaaatgtct ttatcacaac aacctatgcc
     5941 tacgctattt cacggacaac ctttaagtat cgcagatttt ttaccatctt cgtccttctc
     6001 agtatgttgt tcaacgctgg tttggtacca ggttatatca tggtgacccg tgtacttcag
     6061 cttggtgaca ctgtttgggc cttgattgtt ccaatgcttc tctcaccatt caatatcatc
     6121 ttgatgcgtt ccttcttcaa gaagaccatt ccagaagcca ttctcgaatc ggctcgtatc
     6181 gatggtgcca gtgaggcccg gattttcttc caaatctgtt tgccattgtc actaccaggt
     6241 atcgcaacca tcacgctttt gacagctctt ggtttctgga atgactggtt caacgccctt
     6301 ctttacatca agagtgacaa cttgtatcca ttgcaatatt tgctcatgca aatccaacaa
     6361 aatatggact acattgccaa agcggtcggc ttgactggtc aactgggagt tgctctaccg
     6421 aaagaaacag gtcgtatggc catggttgtg gttgcgaccc ttccaatcgc gattttatat
     6481 ccattcttcc aacgctactt tgtaaaaggt ttgactatcg gtggtgtgaa agaatagtgc
     6541 ttattgaaaa agaacatttc tcagttccca acttcccttg tgtgaagtta atactctttg
     6601 aaaatcaaat tcaaaccgcg tcaacgtcgc cttgccgtag atatatgtaa ctgacttcgt
     6661 cagtcttatc tacaacctca aagcagtgct ttgagcagcc tgcgactagt tttctagttt
     6721 gctctttgat tttcattgag tataagatca ttacattgtt tataagttta aaaataaaaa
     6781 aaggagtttt tatcatgaaa aactggaaaa aatatgcttt tgcatctgct agtgtagtcg
     6841 ctctggctgc aggtcttgct gcttgtggaa atttgacagg taacagcaaa aaagctgctg
     6901 attcaggtga caaacctgtt atcaaaatgt accaaatcgg tgacaaacca gataacttgg
     6961 atgaattgtt agcaaatgcc aacaaaatca tcgaagaaaa agttggtgct aaattggata
     7021 tccaatacct tggctggggt gactatggta agaaaatgtc agttatcaca tcatctggtg
     7081 aaaactatga tatcgccttt gcagataact atattgtaaa tgctcaaaaa ggtgcttatg
     7141 ctgacttgac agaattgtac aaaaaagaag gtaaagacct ttacaaggca cttgatccag
     7201 cttatatcaa gggtaatact gtaaatggta agatttacgc tgtaccagtt gcagccaacg
     7261 tagcatcatc tcaaaacttt gccttcaacg gaactctcct tgccaaatat ggtatcgata
     7321 tttcaggtgt tacttcttac gaaactcttg agccagtctt gaaacaaatc aaagaaaaag
     7381 ctccagacgt agtaccattt gctattggta aagttttcat cccatctgat aactttgact
     7441 acccagtagc aaacggtctt ccattcgtta ttgaccttga aggcgatact actaaagttg
     7501 taaaccgtta cgaagtacct cgtttcaaag aacacttgaa gactcttcac aaattctatg
     7561 aagctggcta cattccaaaa gacgtcgcaa caagcgatac ttcctttgac cttcaacaag
     7621 atacttggtt cgttcgtgaa gaaacagtag gaccagctga ctacggtaac agcttgcttt
     7681 cacgtgttgc caacaaagat atccaaatca aaccaattac taacttcatc aagaaaaacc
     7741 aaacaacaca agttgctaac tttgtcatct caaacaactc taagaacaaa gaaaaatcaa
     7801 tggaaatctt gaacctcttg aatacgaacc cagaactctt gaacggtctt gtttacggtc
     7861 cagaaggcaa gaactgggaa aaaattgaag gtaaagaaaa ccgtgttcgc gttcttgatg
     7921 gctacaaagg aaacactcac atgggtggat ggaacactgg taacaactgg atcctttaca
     7981 tcaacgaaaa cgttacagac caacaaatcg aaaattctaa gaaagaattg gcagaagcta
     8041 aagaatctcc agcgcttgga tttatcttta atactgacaa tgtgaaatct gaaatctcag
     8101 ctattgctaa cacaatgcaa caatttgata cagctatcaa cactggtact gtagacccag
     8161 ataaagcgat tccagaattg atggaaaaat tgaaatctga aggtgcctac gaaaaagtat
     8221 tgaacgaaat gcaaaaacaa tacgatgaat tcttgaaaaa caaaaaataa tcagctaaat
     8281 tgatttcgtg tattcattcc taactcctaa aataagaatc actgctttcc tcagattggt
     8341 ctggggaggg cagtggtttt ttgggcacaa ggatatagat atccctgttt tctcttgtcc
     8401 ttattttaac cattcaggaa atttcgagaa tcctctacaa tttccagtca aataaattgc
     8461 attcgttttc tcaagcaggt atactagtgt agataaataa aaaatttaga aaatttaaga
     8521 atagaaaaga gaacaaatct tatggcaaaa gatattcgtg tcttacttta ctacctttat
     8581 actccaattg aaaatgcaga gcaatttgct gcagaccact tggctttctg taaatcaatc
     8641 ggccttaaag gccgtatcct agtcgctgac gagggaatta acggaacagt ttcaggtgac
     8701 tatgaaacaa ctcaaaaata catggactac gttcacagcc ttccaggaat ggaagatctc
     8761 tggttcaaga ttgacgaaga aagtgaacaa gccttcaaga agatgtttgt tcgctacaag
     8821 aaagaaattg tccaccttgg tttggaagac aacgactttg acaatgacat caacccactt
     8881 gaaacaacag gtgcttactt gtctccaaaa gagttcaaag aagcgcttct tgataaagat
     8941 accgttgtcc ttgacacacg taacgattat gagtacgacc taggacattt ccgtggggct
     9001 attcgcccag atattcgcaa cttccgtgag ttaccacaat gggtccgtga caacaaagaa
     9061 aaattcatgg acaagcgtgt cgtggtttac tgtacaggtg gtgttcgctg tgagaaattc
     9121 tcaggctgga tggttcgtga aggttacaaa gatgttggcc aattgcacgg aggaatcgca
     9181 acttacggta aagacccaga agttcaaggt gagctttggg atgggaaaat gtacgtcttt
     9241 gacgagcgta ttgccgttga tgtcaaccat gtcaacccaa ccatcgtagg gaaagactgg
     9301 tttgatggaa caccatgtga acgttatgtc aactgtggaa atcccttctg taaccgtcgt
     9361 atcttgacat cagaagaaaa tgaagacaag taccttcgtg gatgctcaca cgagtgccgt
     9421 gttcacccac gtaaccgcta tgtttcaaaa aatgaattga cacaagctga agtgattgag
     9481 cgcctagccg ctatcggtga aagcttggat caggcagcta ctgtataaga tcaaacagtc
     9541 ctcaggggct gtttttctat gctttgtact caaaaatcta atactcaatg aaaatcaaag
     9601 agcaaactag gaagctagct gcaggctgct caaagcactg ctttgaggtt gtagataaga
     9661 ctgacgaagt cagttacata tatctacggc aaggcgaagc tgacgcggtt tgaagagatt
     9721 ttcgaagaat ataaagtttg tttttgtatc tttcagaaaa ataaggtata ctgtatgtaa
     9781 acgatttcaa aggagtccag ttatggcaaa aacatttttt attccaaata aacagagcat
     9841 tttaggagaa caagagattt tgaatgccaa gtcgatcttg gccttgctag acggtttgga
     9901 gtcacatagc tatgatgtag tctatctccg tcagcctctt aatcgtctgt gcgataatgg
     9961 ggcaatcaca atttcttttt aaggtcagtt atgctgatgg tcaaaaggct taccgtgtcg
    10021 atcttcctga cctactaaca aagacagact ggcagattat caagtcattt ttagatgctt
    10081 tgcttgctta tacagggact gatattgaag ggctagatgg ttttgatttt gaagcttatt
    10141 tccaagcaag tattcaagcc tatctagcag accctgtagc tcgttttacg atttgccaag
    10201 gaatttttaa tcctattttc tttagtcgtg agaacttgaa aagcttttta gaggcagatg
    10261 gcttggccca gtttgaagcg cgtgtgcgtg cggttcaaga gacagatgcc tactttgcaa
    10321 gagtttcctt ctatcaggat ggagaagggc aagtgcacgg tgtttatcat ttggctcaag
    10381 gcgtcaagac cgttttaccg agagaaccat ttgttcctgc tgcctatatg gagcaattgg
    10441 tggataagga agtgcagtgg gagatcgact tggttcaaat cacaggagat ggctctaaac
    10501 cagaagacta tgaagccatc gcccgcttgg actatgcaaa attcctagag tcactaccat
    10561 cagcatttta ccaccaacta gacgccaatc aattagaagt acaacccatc ctaggacaag
    10621 attttaaaac attagcacaa gaaaagtaaa gcagaagcag gtcaatcgac ttgctttttt
    10681 gaaatagaaa aatcctgcca aggatgacag gattgaattt taaagaaagg ccaagatacg
    10741 aagataatct ccaatcagtg ccacttcagc tacaaagaag aggaggataa taactccgtt
    10801 cacaaggaca gacaagaata attgatagaa ggagtcggtt tcacttgctt gacttggtct
    10861 tgtaatgata tggagactgg caagcagaat gattccaatg ctaatcacac acaagagggc
    10921 tgtaaatcgt aggctatcaa agaaagcaaa gaaactagca atagcagtga ggaagattgg
    10981 aattgccaag agttgactat attgttggag aaccttgtct agcgtccagt ccttttcctg
    11041 gtggataaat cgtctcacaa cgaaactacc caagaggaat gaaaagaaga agagtgttgt
    11101 cgctactagg atagagatga tagaaaaaag agttaaagga gctagctgct cagggaagcg
    11161 actgttaatg cttgctatat gtccatagta agcatgtttg atgtgataga tactaaagaa
    11221 aaaggaagat gcagaaaaca gaatgagcaa gagaaaggct gtgtaactgt gtgtgatact
    11281 tgtttccaac ttacttgtag gagatttgat cgcttccact agccaagacc aaaaatcaag
    11341 cacttgctct ttccatttat ccctagattt tggagcttgg tcggggatat aaggactttc
    11401 taaagattta ctgataagaa gtggctcttt cgtggttgct ttttgctgag gaagagcttc
    11461 ttggctctct tcagctatag tgactttttc tgtttcttta gaaaggtctg gctcttcttc
    11521 agtagaatta gatgccttct tttcttctat ttctgttctc gcttcactgt cttcaggagt
    11581 ttcaattttc tcttcttgct ggctttccag ttcgacttca gcttgagaga cttcctcctc
    11641 tacttgagta ttttttccaa ttggtgtatc gagatcggct atcgtttctt cagccttgtc
    11701 tgcaacctct tgagcttgct cttcaggctt gttcttgctt gttgttttta caaaatcatt
    11761 actttcaaac cattcttgtt tcatggtaga acctcctttt ggttagataa atatgcttcc
    11821 atagtagcag atgtaagcgt ttttgtcaac gtctgcttgg tgtggatatt agatcaatat
    11881 tatcatcaga tctcgcaatg agttgatcct tgacatcggt tttttcagtt ttgtaagggt
    11941 tgcttaattc cgtacctctt gattcaggct tttctcttgt gaattggaag atagaaccat
    12001 agttgcttga gatgtcccag ttaattcgtt ggttttcttt ctggtctagg atgattctga
    12061 gataatcttt ggcagtcagt tcaaccttac catggacttg gatattttca gcgtggaagt
    12121 gattatctgt tgactctagc tgactatctg taagaactgt atcaaagata ttaacgatat
    12181 tgggcgttgt gagtttactg tttttgatac gacttccttc aattcggagg atatagctgt
    12241 ttgtattgag ggtcgcattt tcaaggctag catttatgat ggtggtttgt ccgcgattgg
    12301 ctgagatgtt gatccctttt agagttctcc cttttggtag tcggagaata acttcttcaa
    12361 aacgactaga gtagctactt gcgatatgaa gaatcccacc aattccagaa gagagaaacg
    12421 gagtttcaga cagtttctta tcagtgagac tcagagttct atcgttctga ttggtgataa
    12481 gatcatggtg agcagaaaga gatggatggt aagaaatgtg gatttgatca tcgaaagagt
    12541 ctgtgatggt gagcgtgtgt tggtggagag taatttctag gttttcgact tccttgccaa
    12601 aggttagctt ttccgtacgg ctatcataga caggttcttt ggacatggaa agtaggctct
    12661 taatcccgtc agattggata cctacaaaaa gcaggataaa gccgataacg gtagtcacca
    12721 caccaaagat gagaaatcct tttgtccatt tacgcatgct gattacctct ctttcctttt
    12781 ttaagaacaa attgtaccag acgaacaatg agtagaccga agaagcgagc tacataggaa
    12841 atgccaagta aaactagcga agaagcaccg atagccagta aaccagaacc aaaaatcaag
    12901 ataaaggctg atttggcttg ggcgaggata gtgaaacttt caactaaaaa taggaatccg
    12961 ccgatgatac ccagtatgga aactgcaaag aaagccagaa tgacagtcaa agcggctaca
    13021 aggattgcga acagggtcac gaggatggcg attcccagag gaatgccgat aggtgctgca
    13081 aggagggcta acaaggcgat atgtaaaatt tgtcggttat ttttttgagc gggtgcttca
    13141 ttgatttttt tatcgagaag attggataga acttcgtggg ccgcttcttt gggagttccc
    13201 aaactagcga tgagttcttc ttctccttcg actccagcat cgtcaaagag ctctctgaaa
    13261 tagtccatgg cttcgatacg gtcagcttca ggtagtttct tgagatagag ttctagctga
    13321 gtcaggtatt cagttcttgt catggcggat actcccttct atgatgccat tgatggtgtc
    13381 tgtatagagt gcccattcat cttttagggt caagagctgc tctataccac cgtttgtcaa
    13441 ggagtagtat ttgcgcatgc gaccttggaa ctctctagaa taggttgtca gaaagctatt
    13501 gccttccaat tttttgagaa tgggatagag tgtggattct ttgatattag cgatcagctt
    13561 aatggtttgg ctaatctcat aaccataaga atcaccctgc tccagtacgg ccaagatgag
    13621 aaattcaatc aaggcagagg atgttggaaa gtacatggga aacctccttt tctaatgtgt
    13681 aagattttta tatataattt ttctacacat acattgtaca tctaaaagaa agccctgtca
    13741 agagaaatgt gtaaaatttt tatatataaa aaacttctag ctaaaactag aagtttaaag
    13801 gatcttatcc gctctgtcca ctgtaaagag ggccacagtc atcaggatat cgatgagcaa
    13861 gagggcagct acagatggta cccaagagtg gaacaggtca aaactgtaac caaagagggt
    13921 tggcccaaag gctgctagga tatagcctcc tgtttgagat aggccggaca attgggctgt
    13981 cttttcaggg gcgcttgtct tgagtgaaaa gttgaccatg agataaggga agagggcgct
    14041 ggttgcggtt ccgatgagga gatggatggc aagccagtaa atgaaattat tgattgggaa
    14101 aaagagcatg gaaatgccga ccacaccagc tagtgaaacc agagtgagca tgagctgacg
    14161 gttgcgagta gataaactgg ttgtcaggct tgggatggtc attgaaaaag gaatgctaat
    14221 cagagataag atagaagtca gcaagccagc ttcgtgactg gatagacctg catggataga
    14281 catggtaggt aaccaggtca tgacggtgta aaagatcaag gattgaaaac ctgaaaagat
    14341 aataattgcc caaacctgtt tattacgcat gacctttatt tgactttttt gtttggtttg
    14401 tggagctagt ctatgattat agcggtgatt tgggagccag accaaaaaag ttgctagaca
    14461 gagtaacgtg aggagaagga taagtccttt ccaagaactg gcttgtgtaa tgggcacagc
    14521 tagataggaa gccagagccg ttgcaatccc catagacgtt acatataagg tggtcagaaa
    14581 accaattttc tttggttgat tggcttggat aagactagga agcaggacat tgatgactgc
    14641 gacacttgcc ccaaccatca aggttcctag atagagcagg ggcagattga ttagtcgaat
    14701 aagtgagccg atggtcaaga agaagaggct gtaggtgaag agatgctcca agccgatttt
    14761 ctgagccagt cgggtagaaa atggtgaaaa gagggtaaac ataaggagag gcaggctggt
    14821 caagacacca agcgaactaa cttctacctc cagaccttgc gaaatatttc ccaaaataat
    14881 gggtaaaaca gtaaaaggag ttcgcaagga aacaccaatc aggataatac ctggaacaaa
    14941 aaagagtgat tgctttttca tataatacct cttctagctg attttaataa cagcttattt
    15001 taaggctttt tcactataat gtcaagtaag gtttctggct ttcaagataa aaatgggaaa
    15061 gtcttgaaaa ttatgataga atggtggaag gaaaaattca ggagagtagt agtgactcaa
    15121 aatgttgaaa gtcttctcgt atccattgta atcagtgcat acaatgaaga aaaatatctg
    15181 cctggtctaa ttgaagactt aaaaaatcaa acctatccta aagagaatat tgaaattcta
    15241 tttataaatg ctatgtccac agatgggacc acagctatca ttcagcaatt tataaaggaa
    15301 gatacagagt ttaactcaat tagattgtat aacaatccta agaaaaatca agctagtggt
    15361 tttaacctgg gagttaaaca ttctgtaggg gaccttattt taaaaattga tgctcattca
    15421 aaagttactg agagttttgt aatgaacaat gtggctatta ttcaacaagg tgaatttgtc
    15481 tgtggggggc ctagaccgac gattgtcgaa ggaaaaggaa aatgggcaga gaccttgcat
    15541 cttgttgagg aaaatatgtt tggcagtagc attgccaatt atcgaaatag ttccgaggat
    15601 agatatgttt cttctatttt tcatgggatg tataaacgag aggttttcca gaaggttggt
    15661 ttagtaaatg agcaacttgg ccgaactgaa gataatgata ttcattatag aattcgagaa
    15721 catggttata aaatccgcta tagcccaagt attctatctt atcagtatat tcgaccaaca
    15781 ttcaagaaaa tgctgcatca aaagtattca aatggtttgt ggattggctt gacaagtcat
    15841 gttcagttta agtgtttatc attatttcac tatgttcctt gtttatttgt tttgagtctt
    15901 gtgtttagtc tagcattgtt accgatcaca ttcgtattca taactttact attaggtgcc
    15961 tattttctac ttttgtcatt actcactttg ctgactttat taaaacataa aaatggattt
    16021 ctaattgtga tgccctttct tttattttcc attcactttg cttatggcct tgggacgatt
    16081 gtaggtttaa ttagaggatt taaatggaag aaggagtaca agagaacaat aatttatttg
    16141 gataaaataa gccaaataaa taaaaatatg ctataataac aatatagtaa aactctttta
    16201 aggaggagta gatttctatg aataaaaaac taacagatta tgtgattgat ctggtggaaa
    16261 ttttaaataa acaacaaaag caggttttct ggggaatatt tgatattttc agtatggtgg
    16321 tttccatcat tgtatcttat attttatttt atgggctgat taatccagca cctgttgact
    16381 acattatcta tacgagtttg gccttcttgt tctatcaatt gatgattggt ttttgggggt
    16441 tgaacgcgag cattagtcgt tacagcaaga ttacggattt catgaaaatc ttttttggtg
    16501 tgactgctag cagtgtcttg tcatatagta tctgttatgc cttcttgcca ctcttctcca
    16561 tccgtttcat cattctcttt atcttgttga gtaccttctt gattttattg ccacggatta
    16621 cttggcagtt aatctactcc agacgcaaaa aaggtagtgg tgatggagaa caccgtcgga
    16681 ccttcttgat tggtgccggt gatggtgggg ctctttttat ggatagttac caacatccaa
    16741 ccagtgaatt agaactggtc ggtattttgg ataaggattc taagaaaaag ggtcaaaaac
    16801 ttggtggtat tcctgttttg ggctcttatg acaatctgcc tgaattagcc aaacgccatc
    16861 aaatcgagcg tgtcatcgtt gcgattccgt cgctggatcc gtcagaatat gagcgtatct
    16921 tgcagatgtg taataagctg ggtgtcaaat gttacaagat gcctaaggtt gaaactgttg
    16981 ttcagggcct tcaccaagca ggtactggct tccaaaaaat tgatattacg gaccttttgg
    17041 gtcgtcagga aatccgtctt gacgaatcgc gtctgggtgc agaactgaca ggtaagacca
    17101 tcttagtcac aggagctgga ggttcaatcg gttctgaaat ctgtcgtcaa gttagtcgct
    17161 tcaatcctga acgcattgtc ttgctcggtc atggggaaaa ctcaatctac cttgtttatc
    17221 atgaattgat tcgtaagttc caagagattg attatgtacc tgtgattgcg gacattcaag
    17281 actatgatcg tttgttgcaa gtctttgagc agtacaaacc tgctattgtt tatcatgcgg
    17341 cagcccacaa gcatgttcct atgatggagc gcaatccaaa agaagccttc aaaaacaata
    17401 tccgtggaac ttacaatgtt gctaaggctg ttgatgaagc taaagtgtct aagatggtta
    17461 tgatttcgac agataaggca gtcaatccac caaatgttat gggagcaacc aagcgcgtgg
    17521 cggagttgat tgttactggc tttaaccaac gtagccaatc aacctactgt gcagttcgtt
    17581 ttgggaatgt tcttggtagc cgtggtagtg tcattccagt ctttgaacgt cagattgctg
    17641 aaggtgggcc tgtaacggtg acagacttcc gcatgacccg ttactttatg accattccag
    17701 aagctagccg tctggttatc catgctggtg cttatgccaa agatggggaa gtctttatcc
    17761 ttgatatggg caaaccagtc aagatttatg acttggccaa gaagatggtg cttctaagtg
    17821 gccacactga aagtgaaatt ccaatcgttg aagttggaat ccgcccaggt gaaaaactct
    17881 acgaagaact cttggtatca accgaactcg ttgataatca agttatggat aagattttcg
    17941 ttggtaaggt taatgtcatg cctttagaat ccatcaatca aaagattgga gagttccgca
    18001 ctctcagtgg agatgagttg aagcaagcta ttatcgcctt tgctaatcaa acaacccaca
    18061 ttgaataaaa aagaaaaacg catagtatca agttacacaa ccttggtaat atgcgtttta
    18121 ttatgtagag acttatactc ttcgaaaatc tcttcaaacc acgtcaacgt cgccttgccg
    18181 tatgtatatg ttactgactt cgtcagttct atccacaacc tcaaaacagt gttttgagct
    18241 gacttcgtca gttccatcta caaccttaaa acagtgtttt gagcagcccg cagctagttt
    18301 cctagtttgc tctttgattt tcattgagta ttacttcatt ttcttctgaa atagagttgt
    18361 cgcccagtct atgctattga aaatacgcca aaacttctaa gggtttgtga gcgatataat
    18421 caggttgata gtttagtaga tctgcttgct ctccaaatcc ccaagtgacg gccaatttct
    18481 gaatacctgt ttctcgagct cccagcatat caaacttggt atctccgatg atgatggctt
    18541 gttctggtgc tagttgatgt gtctgtaagg cttggtgaat gacatctgcc ttatggggtg
    18601 cttcagggct agaaccataa ataccatcaa agaaatgatg gatttccaag tttttggcca
    18661 tgtcttgagc agtagatgta ttctttgtcg tggtgatgta gagtggataa ctgctcgata
    18721 actcctcaag caagtctata atctgaggaa agagttgagc ttcatagatg ccttttgcct
    18781 tatagtaaga acgatatatc tgcatggctt cagaaatttg gtctttggac aggcaggtcg
    18841 caaaactact ttcgagaggt ggtcccataa aaccacgaat agttttggca tcagggctag
    18901 gcacccccag ctctttaaag gtataggtaa aggcattgtg aatcccgata gaactatcaa
    18961 cgagggttcc atccaaatcg aaaaaaatcg ctgtgataga ggtcatggtt tctcctattt
    19021 gataagctta ttctccgaaa atctcttttt ggaggcgacg accagtaggg gtggtagcga
    19081 gtccaccttc agctgtttca cgaaaggcag ttggcatgct tgctcctact tggtacatgg
    19141 catcgatcac ttcatccaca gggattttag attcgatacc tgccaaggcc atgtctgctg
    19201 cgatgaaagc aaagctagct cccatggcat tacgtttgac acagggaact tcgaccaaac
    19261 ctgcaacagg gtcacagatg aggcctagca tatttttaat gacaaaggca atagcttgac
    19321 tggcctgata aggtgttcca cctgcagcca gagtcaaggc ggcagcactc atagcagagg
    19381 ctgaaccaac ttcagcttga catccaccct cagcacctga gatggaggca ttgtttgcga
    19441 tgactagtcc aaaggcacca gcagcaaaga ggaaatccaa ttgttgctcg tggctgaggt
    19501 ctaatttttc aatagcagca gtgagaacgg aagggagaca accggcactt cctgcggtag
    19561 gagtagcgca gaccaagccc attttagcat tgtgttcatt gactgcgata gcatttcggg
    19621 cagcagagag aatcgtgtaa tctgataaag ttttttcgtt tttgatgtag tgatccaatt
    19681 tggcagcatc tccacctgtc aggccactac gagatttatt ttcattgagg ccaagttgga
    19741 cagaggcttt cataacttcc agattgcgtt ccatgagaag gaagacttct tcacgttcgc
    19801 gaccggtcaa ttcaaactct gttgtaatca tgagttctgc gacatttcct tgaaagtcca
    19861 gatctgcttg ctcgaccaat tctttgatag aataaaacat gcttcctcct atttaaagaa
    19921 attgacattg tggagatgag ggatttttcg aatttcttcg atagcctcat cacagttgcg
    19981 actgtcaact tcgataatca taatggcttt ttcaccagct ttttcacgag tgacattcat
    20041 ctgggcgata ttgataccat agcgggaaag cgcctctgta acaagggcaa tcatacctgg
    20101 aatatcttga tgaacgatga tgatagtcgg tgtattcata ttgagagaga cggcaaaacc
    20161 attgagttcg gttacctgaa tatttcctcc accgatagaa ataccagtca cgctgatggt
    20221 cttgtgggca tttttaacag taattttagt ggtgttaggg tgaggggcat tgctgtcttt
    20281 ctgaatggtc cagacaatct tgataccacg cttgtgggca atttccagac tatttggaat
    20341 ttcaggatca tctgtatcca ttcctaaaat acctgcaaca agggctaggt ctgttccgtg
    20401 accacgatag gtcttggcaa atgagttaaa aagttggaat tcaacttctg tcggagtatc
    20461 atcaaaaatg gaagagacaa tcttcccaat acgaacagca ccagcggtat ggctactaga
    20521 tgggccaatc ataactggtc cgatgatatc aaagacagat tgaaaacgaa gtgatttcat
    20581 cagtttcccc ttataaaaat tcttatctct attatatcaa agaatgaggg gcttggcttt
    20641 aattgtggat gaaaaccttt ctaatacctc aaatagcata aaaatagtat cttttatgac
    20701 aaaaaacacc ttatttaggg aaataaaaaa taattttgta atatttctac ataaaagtgt
    20761 caagaaacgg taatatttaa agggtatgat agaactatag aaagaaggag aattttcgaa
    20821 tatgaaatca ataactaaaa agattaaagc aactcttgca ggagtagctg ccttgtttgc
    20881 agtatttgct ccatcatttg tatctgctca agaatcatca acttacactg ttaaagaagg
    20941 tgatacactt tcagaaatcg ctgaaactca caacacaaca gttgaaaaat tggcagaaaa
    21001 caaccacatt gataacattc atttgattta tgttgatcaa gagttggtta tcgatggccc
    21061 tgtagcgcct gttgcaacac cagcgccagc tacttatgcg gcaccagccg ctcaagatga
    21121 aactgtttca gctccagtag taagtgaaac agttgtttca actgtaagcg gatctgaagc
    21181 agaagccaaa gaatggatcg ctcaaaaaga atcaggtggt agctatacag ctacaaatgg
    21241 acgttatatc ggacgttacc aattaacaga ttcatacctg aacggtgact actcagctga
    21301 aaaccaagaa cgtgtagcag atgcctacgt tgcaggacgt tacggttcat ggactgctgc
    21361 taaaaacttc tggcttaaca atggctggta ttaagaacta acgaacaaat aatatgtaaa
    21421 aggtcgagga gctccctcga ctttttttat aatttctttg gttgataatg ggtctctact
    21481 tcttttttga gatgagacag catagaagtt tcctcggtca gctccagaag tgagaaacct
    21541 ttttggataa gtttagcatt atctgtacaa atcccaatac ggacatagca gatagcaagc
    21601 ctatcgtagc ttttcttatt cttggcgtcc tccagtaaag tgtagcagat ttgcttacac
    21661 atgtttttat cttgattgta tagatagagt gtggaaaggt ttagcaggat tgctattcgc
    21721 aagtcatata aatgttgata gtttttatag acttctaagc gttgcaagat tttctcggat
    21781 tattgacaaa taaacggaca ttctgataga cgattgccct agcggcttag tgtaaacttt
    21841 acaaatttgg cttgtaattt ttttataaaa ttcacttcag ttacttgaca gttattatat
    21901 tttcgcttat tatatagata aaaggatggg ataggatttt aaaaatttga aagcgctatc
    21961 catattgttt attggactga ttcttgagta atagttagag tgtgcttaat actactctgg
    22021 ttgttcaagg acctgataca gaagcgcacc attctcccgg ttaagagtaa gttcgttgtt
    22081 aaaaaatgaa atgagataga aggaaggtga gtccaatgga ctacgatact tgttgataaa
    22141 ttactatagc tgtttttacg gaacagctct cgataatagg agaaataaat catgagaaaa
    22201 ttagttaaaa ttggtgttgc atctttaatg gtatgtggta tacttgctac tacaaatgct
    22261 ttagcagtat gggttgaggg tggtcaatgg aactatggag taggttggac aggaactttt
    22321 ggatattctg attacttaca ttctactcga tatcatacag caactgttag acatgggggt
    22381 agaacctcta aggattatgc aaaacctgag gcatgggcta gagcttccct caccaagatt
    22441 ccgccaacag gaatggaata tttctatgga tttgagtaaa attcttccct ctcctatttg
    22501 gagagggaaa actgtagtgg aggcactttt atgaaaaaaa tcagtaattt ctgtatgtta
    22561 ctcctgcttc tgtgtaccac tttttttgtt tttaatgtaa actatacacg agaagtggtt
    22621 cggattcaag aaatgggaaa gactgtagat tctttggatt tgtatttgaa agatattaac
    22681 gaacctgcag cgtctgttct tcgatttttt gaggatgtat caaaggagta taaagtctcc
    22741 atcatcaaaa cagacagtgg tgatgaggtg gtcaagtctg gtgtttttga taaagatacc
    22801 ttcccctacc aagagtttgg gatttcttct cttgatttta ccacagatgg tgaaggagtc
    22861 tatagtaata aagaaatttc caataaactt ggtacgattc cgacctttct aaaagccaaa
    22921 cctattcagc ttatgacttt tcaaacctat atcaaggata catctcgtag tttaaatggt
    22981 cgctatacga taacttctac acaagagatg gacaaggata ggattgtaca gaaatggagc
    23041 gattttttca agatagacca ggctaccttg ctagagccga cctacaaaag tgcagtggaa
    23101 gtcataaatc gagatttgct tttatctgcc attgtttttg tcttggctat tttgcttctt
    23161 gtgttagtga cagtgtatca accgatgatg gagatgaaaa gagttggggt acaaaaatta
    23221 cttggttttc aagatagggc tgttttagct gatgttgtaa aaggcaacct ttacctcctc
    23281 ctaggtgggg ctcttgtgat caatctaggc gtgtttttct tgcttgatta taagccaaaa
    23341 gatttgtttc ctatgctgtg gttgtctcat tttttgctgt tgcagcttta tctctttatc
    23401 agttggttga cttacctctt aatccaaaaa atgacaatca gctctctgct gaaaggtttt
    23461 tcatctttca aatttggtct tatcttcaat tatgtgatga aaatagggac aactatttta
    23521 ctgacggcct tactgattgg ggtgggcaga agtttagaac aagaaaacaa agaacttgct
    23581 tatcagcaac agtgggtaag tcaaggtaat tacctgacct tagaaacctt caaactcaat
    23641 gataatctgt ggcaagaaga gctagcaggg tcagggaaat ctacagatta tttctatcga
    23701 ttttatcagg atttggtaga aaaaacgcag gcgggctatg tgcagagtag cagtcttcct
    23761 gtaaaaaatt ttgtccaatc agaacagatt cagcaatatc agttaacaga tacggtggat
    23821 gtttactatg ccaatcgcaa ttttctaaag agcaagggat tcaagctacc agataccggt
    23881 attaaaaaag ttattttgat gccagcaagt acgaaaggtg aagaagataa aaatcagctc
    23941 ttggggaagt taattgcctt tcattcgatg aagtatgaag agcagcaaaa acgaacgata
    24001 gaggagatgg atgtcgagat tgcctattat gaaggagatt ggtcattttt cccatatagt
    24061 gataagcgaa aggaaaatct ctccaatcca attattagct tggtcaatga ttctgatatg
    24121 atgtgggatg agaaagcctc cctgtcaaca actggcttaa ataatccgat taaaattgaa
    24181 aatacggttc aacatcaaaa agagattaca gagttagttg agaaattgtc agatggaaat
    24241 tatttaaaat tttcatctat tcaagccatt caacaagaga aagtggattc ttatcgagat
    24301 gctgttcgga attttaacct actctttgct ttgtttggtc tccttagcat gatgatttcc
    24361 tacttcttac tagtaacaac tttcttattg aagcgcaggg atatcattac caagaagttt
    24421 atggggtgga aactggtcga tcgctaccgt cctctcctcg ttctgctctt gctgggctat
    24481 agtttccctc ttctagtctt gattttcttt gcccatgcgt tcttaccact tctactgttt
    24541 gcaggtttta catgtctgga tatactattt gtgctaggct tagcttctag gatggagaaa
    24601 agaagtctag tagagttatt gaaagggggc atcttatgat tgagttgaaa aatattacca
    24661 aaaccattgg gggaaaagtg attttggata acttatctct caggattgat cagggggatt
    24721 tggtagctat tgttggtaag agtggtagtg ggaagtcgac cttgttaaat ttattgggtt
    24781 tgatagatgg tgattatagc ggacggtatg agatttttgg tcagacaaat ctagcggtta
    24841 attctgctaa gtcgcaaaca ataatccgtg aacatatctc ttatctgttt caaaattttg
    24901 ccctgattga tgatgaaacg gtcgagtaca atctcatgct ggcgctgaaa tatgtgaaat
    24961 tgcctaagaa agacaagctc aaaaaggtgg aagagatttt agagagagta ggtttgtcag
    25021 ctactttgca tcaaagggtc tccgagttgt ctgggggcga acaacaacga attgcagttg
    25081 ctagagccat cttaaaaccc agccagctga ttttagccga tgaacctaca ggttcgctgg
    25141 atcctgaaaa tagagatttg gtcttgaagt ttctcttaga gatgaatcga gaggggaaaa
    25201 cagtcattat cgtgacccac gatgcttatg tagcccaaca atgtcatcga atcattgaat
    25261 taggcgaggg aaaatgagtt cgttcagctt catttgaccg actgaatact catatttttc
    25321 agagagaaat agcataaata ggcctaggaa tgatattttt atgtcatttt cctgggtttt
    25381 tctgttttaa attgaaaaaa aatacaattt aggcttgaca aaggatgagt ataggagtat
    25441 tatttataca ataaaaaaga ataaacataa aggaggcttt gttatgaata agatgaagaa
    25501 ggtgttgatg acgatgtttg gtttagtgat gctcccccta ctatttgctt gtagtaacaa
    25561 tcaatcggct ggaattgaag ccatcaagtc caaaggaaaa ttggttgtag ccctcaatcc
    25621 agattttgct ccatttgaat atcaaaaagt ggttgatggg aaaaatcaga ttgtgggttc
    25681 agatatcgaa ttagccaagg ctatcgcaac agaactaggt gtcgaattgg aactatctcc
    25741 tatgagtttt gacaatgtac tggctagcgt tcaatcagga aaagctgacc ttgccatatc
    25801 aggtgtttct aagacagatg aacggagcaa ggtgtttgat ttttcaactc cctactatac
    25861 tgcaaaaaat aaactcattg tcaaaaaatc tgatttagcc acttatcagt ctgtcaacga
    25921 tttggcgcag aaaaaggtcg gagcgcagaa aggttcgatt caagagacga tggcgaaaga
    25981 tttgctacaa aattcttccc tcgtatctct gcctaaaaat gggaatttaa tcacagattt
    26041 aaaatcaggg caagtggatg ccgttatttt tgaagaaccc gttgccaagg gatttgtgga
    26101 aaataatcct gatttagcaa tcgcagacct caattttgaa aaagagcaag atgattccta
    26161 tgcggtagcc atgaaaaaag atagcaagga attgaaagag gcagtcgata aaaccattca
    26221 aaagttgaag gagtctgggg aattagacaa actcattgag gatgccttta aagcgtccat
    26281 tgaaaaatag aaagaaggaa aagaacatga gtaaagaaaa agtaattttg gcctattctg
    26341 gcggtttaga cacatcagtt gctattacct ggctgaagaa agactatgat gttgttgcag
    26401 tttgtatgga tgtgggtgaa gggaaagact tagatttcat ccatgataag gctcttaagg
    26461 ttggggcagt cgaatcttat gtcattgatg ttaaggacga atttgctaca gattatgtgc
    26521 tagtagctct ccagtcacat gcctactatg aacaaaagta ccccttggta tctgccttga
    26581 gccgccctct tatttctaaa aaattggttg aaatagcgca tcagatagga gcgactacaa
    26641 ttgctcatgg ttgtaccggt aaggggaatg accaagtcga ataccagatt gcagtcgcta
    26701 agaaagcgaa tgaagctaaa aagtgatgga gtgatgggtt cagaataaga ggttggtcga
    26761 ttggtagcct ctttcttgtc gttgaaaaag tgagatatat tgacttttga aaaaaatgtc
    26821 ataattgagt tgggataaac gtaaaagtca tactttctcg ttaaatcgtt cggcgattca
    26881 tggtgacatg gacacatagt agtaaacaca ctatgtggct tggcagagct aaaaacttct
    26941 ggtttaacaa tggctggtat taagaactaa cgaacaaat
//
LOCUS       DAVLXH010000026        26093 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00028199
            SAMN33607166-rid17955573.denovo.026, whole genome shotgun sequence.
ACCESSION   DAVLXH010000026 DAVLXH010000000
VERSION     DAVLXH010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607166
            Sequence Read Archive: SRR23725544
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 26093)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26093)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721421.1
            Genome Coverage       :: 115x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:42:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,210
            CDSs (total)                      :: 2,161
            Genes (coding)                    :: 2,023
            CDSs (with protein)               :: 2,023
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 73 of 138
            Pseudo Genes (incomplete)         :: 60 of 138
            Pseudo Genes (internal stop)      :: 40 of 138
            Pseudo Genes (multiple problems)  :: 31 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26093
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607166-rid17955573.denovo.026"
                     /strain="AUSMDU00028199"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1349"
     gene            complement(223..1893)
                     /locus_tag="VYO11_001207"
     CDS             complement(223..1893)
                     /locus_tag="VYO11_001207"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HEV1595780.1"
                     /translation="MKTDIEIAQSIELKPIVDVVEKLGISYDDLELYGKYKAKLSFDK
                     IRAVESNPVGKLILVTAINPTPAGEGKSTLTIGLADALNKIGKKTMIAIREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALIDNHLHQGNELGIDQRR
                     ILWKRVVDLNDRALRHVTVGLGGPLNGIPREDGFDITVASEIMAILCLATDIEDLKLR
                     LANIVIGYRYDRTPVSVGDLQVEGALALILKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSVLATTTALHLADYTVTEAGFGADLGAEKFLDIKTPNLPTSPDAVVIVATLRAL
                     KMNGGVAKDALTEENVEAVRAGFANLKRHVENIRKFGIPAVVAINEFVSDTEAEIAAL
                     KELCASIDVPVELASVWADGAEGGVALAETVVKTIAENPANYKRLYDNDLSVQEKIEK
                     IVTEIYRGSKVNFEKKAQTQIAQIVQNGWDKLPICMAKTQYSFSDNPNALGAPENFEI
                     TIRELVPKLGAGFIVALTGDVMTMPGLPKRPAALNMDVESDGTVLGLF"
     gene            2123..2812
                     /gene="coaB"
                     /locus_tag="VYO11_001208"
     CDS             2123..2812
                     /gene="coaB"
                     /locus_tag="VYO11_001208"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000699493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HEV1595781.1"
                     /translation="MKILVTSGGTSEAIDSVRSITNHSTGHLGKIITETLLSAGHEVC
                     LITTKRALKPESHPNLSIREITNTKDLLIEMQERVQDYQILIHSMAVSDYTPVYMTGL
                     EEVQASSNLKEFLSKQNHQAKISSTDEVQVLFLKKTPKIISLVKEWNPTIHLIGFKLL
                     VDVTEDHLVDIARKSLIKNQADLIIANDLTQISADQHRAIFVEKNQLQTVQTKEEIAE
                     LLLEKIQAYHS"
     gene            2824..3375
                     /gene="coaC"
                     /locus_tag="VYO11_001209"
     CDS             2824..3375
                     /gene="coaC"
                     /locus_tag="VYO11_001209"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HEV1595782.1"
                     /translation="MANILLAVTGSIASYKSADLVSSLKKQGHQVTVLMTQAATEFIQ
                     PLSLQVLSQNPVHLDVMKEPYPDQVNHIELGKKADLFIVVPATANTIAKLAHGFADNM
                     VTSTALALPSHIPKLIAPAMNTKMYDHPVTQNNLKTLETYGYQLIAPKESLLACGDHG
                     RGALADLTIILERIKETIDEKTL"
     gene            3359..3922
                     /locus_tag="VYO11_001210"
     CDS             3359..3922
                     /locus_tag="VYO11_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEV1595783.1"
                     /translation="MKKRSNIAPIAIFFATMLVIHFLSSLIFNLFPFPIKPTIVHIPV
                     IIASIIYGPRVGVTLGFLMGLLSLTVNTITILPTSYLFSPFVPNGNIYSAIIAIVPRI
                     LIGLTPYLVYKLMKNKTGLILAGALGSLTNTIFVLGGIFFLFGNVYNGNIQLLLATVI
                     STNSIAELVISAILSLAIVPRLQTLKK"
     gene            4204..4731
                     /locus_tag="VYO11_001211"
     CDS             4204..4731
                     /locus_tag="VYO11_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEV1595784.1"
                     /translation="MNTRKKTQFMTMTALLTAIAILIPIVMPFKIVIPPASYTLGSHI
                     AIFIAMFLSPLMAVFVILASSFGFLMAGYPMVIVFRAFSHISFGALGALYLQKFPDTL
                     DKPKSSWVFNFVLAVVHALAEVLACVLFYATSGTNVENMFYVLFVLVGFGTIIHSMVD
                     YTLALAVYKVLRKRR"
     gene            4743..5258
                     /locus_tag="VYO11_001212"
     CDS             4743..5258
                     /locus_tag="VYO11_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HEV1595785.1"
                     /translation="MTKDRKQALLQLLKEAPKALNGQSLAEHFHVTRQVIVQDIAILR
                     ADGAPILSTNRGYIYKQIDTNPYVHKLFKVKHEVEEIGQELLAIVDNGGHVQNTLIDH
                     PVYGEIETLLKLSCRRDVQHFLEQVEHSDFRPLSELTDGIHYHLVEAETQQDLHYIEE
                     ALDQLGYLVKD"
     gene            complement(5255..5722)
                     /locus_tag="VYO11_001213"
     CDS             complement(5255..5722)
                     /locus_tag="VYO11_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000085289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEV1595786.1"
                     /translation="MSRSQLTILTNICLIEDLETQRVVMQYRAPENNRWSGYAFPGGH
                     VENDEAFAESVIREIYEETGLTIQNPQLVGIKNWPLDTGGRYIVICYKATEFSGTLQS
                     SEEGEVSWVQKDQIPNLNLAYDMLPLMEMMEAPDKSEFFYPRRTEDDWEKKIF"
     gene            complement(5796..6284)
                     /locus_tag="VYO11_001214"
     CDS             complement(5796..6284)
                     /locus_tag="VYO11_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1595787.1"
                     /translation="MTVIIKSMETPKEIEGKSLVHWQMWRESYDDLLPAEFQDTMTLE
                     RCRFFSQKYPENTLIAMDGVKVVGFISYGNFRDETIQAGEIIALYVLKDYYGKGIAQK
                     LMKAALTALNHFSEIFLWVLKDNKRAIAFYQKMGFTFDGQEKILELGKPIKEKRMVFY
                     SK"
     gene            complement(6250..6813)
                     /locus_tag="VYO11_001215"
     CDS             complement(6250..6813)
                     /locus_tag="VYO11_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1595788.1"
                     /translation="MIYLRKLKREDLMSLWEMAYSQLNPVWKQYDAPYYDDYQYFSNF
                     KEFELQKSESILSNSNRLGIFVDDKLVGTVSRYWVCKQTRWMELGIGIYDKKFWNTGI
                     GKVAMLQWIDRTFQDYLELEHLGLTTWSGNLGMMKLAEKLRMKKEAHIPKVRYYQGKY
                     FDSIKYGILREDWEKINDGYYQINGNS"
     gene            complement(6823..8811)
                     /gene="uvrB"
                     /locus_tag="VYO11_001216"
     CDS             complement(6823..8811)
                     /gene="uvrB"
                     /locus_tag="VYO11_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit B"
                     /protein_id="HEV1595789.1"
                     /translation="MINHITDNQFKLVSKYQPSGDQPQAIEQLVDNIEGGEKAQILMG
                     ATGTGKTYTMSQVISKVNKPTLVIAHNKTLAGQLYGEFKEFFPENAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSALLERNDVIVVASVSCIYGLGSPKEYA
                     DSVVSLRPGLEISRDKLLNDLVDIQFERNDIDFQRGRFRVRGDVVEIFPASRDEHAFR
                     VEFFGDEIDRIREVEALTGQVLGEVDHLAIFPATHFVTNDDHMEVAIAKIQAELEEQL
                     AVFEKEGKLLEAQRLKQRTEYDIEMLREMGYTNGVENYSRHMDGRSEGEPPYTLLDFF
                     PDDFLIMIDESHMTIGQIKGMYNGDRSRKEMLVNYGFRLPSALDNRPLRREEFESHVH
                     QIVYVSATPGDYENEQTETVIEQIIRPTGLLDPEVEVRPTMGQIDDLLGEINARVEKN
                     ERTFITTLTKKMAEDLTDYFKEMGIKVKYMHSDIKTLERTEIIRDLRLGVFDVLVGIN
                     LLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNSEGHVIMYADTVTQSMQ
                     RAIDETARRRKIQMAYNEEHGIVPQTIKKEIRDLIAVTKAVAKEEDKEVDITSLNKQE
                     RKELVKKLEKQMQEAVEVLDFELAAQIRDMMLEVKALD"
     gene            complement(8888..9842)
                     /locus_tag="VYO11_001217"
                     /pseudo
     CDS             complement(8888..9842)
                     /locus_tag="VYO11_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000792120.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
     gene            10012..12177
                     /locus_tag="VYO11_001218"
     CDS             10012..12177
                     /locus_tag="VYO11_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HEV1595790.1"
                     /translation="MKKKFLAFLLILFPIFSLGIAKAETIKIVSDTAYAPFEFKDSDQ
                     TYKGIDVDIINKVAEIKGWNIQMSYPGFDAAVNAVQAGQADAIMAGMTKTKEREKVFT
                     MSDTYYDTKVVIATTKSHKISKYDQLTGKTVGVKNGTAAQRFLETIKDKYGFTIKTFD
                     TGDLMNNSLSAGAIDAMMDDKPVIEYAINQGQDLHIEMDGEAVGSFAFGVKKGSKYEH
                     LVTEFNQALAEMKKDGSLDKIIKKWTASSSSAVPTTTTLAGLKAIPVKAKYIIASDSS
                     FAPFVFQNSSNQYTGIDMELIKAIAKDQGFEIEITNPGFDAAISAVQAGQADGIIAGM
                     SVTDARKATFDFSESYYTANTILGVKESSTIASYEDLKGKTVGVKNGTASQTFLTENQ
                     SKYGYKIKTFADGSSMYDSLNTGAIDAVMDDEPVLKYSISQGQKLKTPIAGTPIGETA
                     FAVKKGTNPELIEMFNNGLANLKANGEFQKILDKYLASESSTASTSTVDETTLWGLLQ
                     NNYKQLLSGLGITLALALISFAIAIVIGIIFGMFSVSPYKSLRVISEIFVDVIRGIPL
                     MILAAFIFWGIPNFIESITGQQSPINDFVAGTIALSLNAAAYIAEIVRGGIQAVPVGQ
                     MEASRSLGISYGKTMRKIILPQATKLMLPNFVNQFVIALKDTTIVSAIGLVELFQTGK
                     IIIARNYQSFKMYAILAIFYLVIITLLTRLAKRLEKRIR"
     gene            12177..12917
                     /locus_tag="VYO11_001219"
     CDS             12177..12917
                     /locus_tag="VYO11_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV1595791.1"
                     /translation="MAKLKIDVNDLHKHYGKNEVLKGITTKFYEGDVVCIIGPSGSGK
                     STFLRSLNLLEEVTSGHITVNGYDLTEKTTNVDHVRENIGMVFQHFNLFPHMSVLDNI
                     TFAPIEHKLMTKEEAEELGMELLEKVGLADKANANPDSLSGGQKQRVAIARGLAMNPD
                     IMLFDEPTSALDPEMVGDVLNVMKELAEQGMTMIIVTHEMGFARQVANRVIFTADGEF
                     LEDGTPDQIFDNPQHPRLKEFLDKVLNV"
     gene            13066..14553
                     /locus_tag="VYO11_001220"
     CDS             13066..14553
                     /locus_tag="VYO11_001220"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HEV1595792.1"
                     /translation="MSSKVIVTIFGASGDLAKRKLYPSLFRLYKSGNLSKHFAVIGTA
                     RRPWSKEYFESVVVESILDLADSTEQAQEFASHFYYQSHDVNDSEHYIALRQLQAELN
                     EKYQAEHNKLFFLSMAPQFFGTIAKHLKSENIVDGKGFERLIVEKPFGTDYATASKLN
                     DELLATFDEEQIFRIDHYLGKEMIQSIFAVRFANLIFENVWNKDFIDNVQITFAERLG
                     VEERGGYYDQSGALRDMVQNHTLQLLSLLAMDKPASFTKDEIRAEKIKVFKNLYHPTD
                     EELKEHFIRGQYRSGKIDGMKYISYRSEPNVNPESTTETFTSGAFFVDSDRFRGVPFF
                     FRTGKRLTEKGTHVNIVFKQMDSIFGEPLAPNILTIYIQPTEGFSLSLNGKQVGEEFN
                     LAPNSLDYRTDATATGASPEPYEKLIYDVLNNNSTNFSHWDEVGASWKLIDRIEELWA
                     ENGAPLHDYKAGSMGPQASFDLLEKFGAKWTWQPDIAYRQDGRLE"
     gene            complement(14599..15876)
                     /gene="ftsY"
                     /locus_tag="VYO11_001221"
     CDS             complement(14599..15876)
                     /gene="ftsY"
                     /locus_tag="VYO11_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HEV1595793.1"
                     /translation="MGLFDRLFGKKEEPKIEEVVKEALENLDLSEDVDPTFTEVEEVS
                     QEEAEVEIVEQAVFQEEEIQDTVEESLDLEPVIEVSQKEVKEFPHSEEGNTEFLETVE
                     ENNSEVLEAERPQTEETVQEKYDRSLKKTRTGFGARLNAFFANFRSVDEEFFEELEEL
                     LIMSDVGVQVASNLTEELRYEAKLENAKKPDALRRVIIEKLVELYEKDGSYDESIHFQ
                     DNLTVMLFVGVNGVGKTTSIGKLAHRYKRAGKKVMLVAADTFRAGAVAQLAEWGRRVD
                     VPVVTGPEKADPASVVFDGMERAVAEGIDILMIDTAGRLQNKDNLMAELEKIGRIIKR
                     VVPEAPHETFLALDASTGQNALVQAKEFSKITPLTGIVLTKIDGTARGGVVLAIREEL
                     NIPVKLIGFGEKIDDIGEFNSENFMKGLLEGLI"
     gene            complement(15880..16698)
                     /locus_tag="VYO11_001222"
     CDS             complement(15880..16698)
                     /locus_tag="VYO11_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV1595794.1"
                     /translation="MADIKLIALDLDGTLLTTDKRLTDRTKETLKAARDRGIKVVLTT
                     GRPLKAMDFFLHELGTDGHEDEYTITFNGGLVQKNTGEILDKTVFSYDDVARLYEETE
                     KLSLPLDAISEGTVYQIQSDQESLYAKFNPALTFVPVDFEDLSNQMTYNKCVTAFAQE
                     PLDAAIQKISPELFDQYEIFKSREMLLEWSPKNVHKATGLAKLISHLGIDQSQVMACG
                     DEANDLSMIEWAGLGVAMQNAVPEVKAAANVVTPMTNDEEAVAWAIEEYVLKEN"
     gene            complement(16698..17492)
                     /locus_tag="VYO11_001223"
     CDS             complement(16698..17492)
                     /locus_tag="VYO11_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000153012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV1595795.1"
                     /translation="MTIKLVATDMDGTFLDGNGRFDMDRLKSLLASYKEKGIYFAVAS
                     GRGFLSLEKLFADVRDDIIFIAENGSLVEYQGQDLYEVTMSRDFYLATFEKLKTSPYV
                     DINKLLLTGKKGSYVLDTVDETYLKVSQHYNENIQKVASLEDITDDIFKFTTNFTEET
                     LEDGEAWVNENVPGVKAMTTGFESIDIVLDYVDKGVAIVELVKKLGITMDQVMAFGDN
                     LNDLHMMQVVGHPVAPENARPEILELAKTVIGHHKDQSVIAYMEGL"
     gene            complement(17489..21028)
                     /gene="smc"
                     /locus_tag="VYO11_001224"
     CDS             complement(17489..21028)
                     /gene="smc"
                     /locus_tag="VYO11_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HEV1595796.1"
                     /translation="MYLKEIEIQGFKSFADKTKVVFDQGVTAVVGPNGSGKSNITESL
                     RWALGESSVKSLRGGKMPDVIFAGTESRKPLNYASVVVTLDNHDGFIKDAGQEIRVER
                     HIYRSGDSEYKIDGKKVRLRDIHDLFLDTGLGRDSFSIISQGKVEEIFNSKPEERRSI
                     FEEAAGVLKYKTRRKETESKLQQTQDNLDRLEDIIYELDNQIKPLEKQAENARKFLDL
                     EGQRKAIYLDVLVAQIKENKAELESTEEELAQVQELLMSYYQKREKLEEENQTLKKQR
                     QDLQAEMAKDQGSLMDLTSLISDLERKLALSKLESEQVALNQQEAQARLAALEDKRNS
                     LSKEKSDKESSLALLEGNLVQNNQKLNRLEAELLAFSDDPDQMIELLRERFVALLQEE
                     ADVSNQLTRIENELENSRQLSQKQADQLEKLKEQLAIAKEKASQQKEELETAKEQVQK
                     LLADYQAIAKEQEEQKTSYQAQQSQLFDRLDNLKNKQARAQSLENILRNHSNFYAGVK
                     SVLQEKDRLGGIIGAVSEHLTFDMHYQTALEIALGASSQHIIVEDENAATKAIDFLKR
                     NRAGRATFLPLTTIKARTISSQNQDAIAVSPGFLGMADELVTFDTRLEAIFKNLLATT
                     AIFDTVEHAREAARQVRYQVRMVTLDGTELRTGGSYAGGANRQNNSIFIKPELEQLQK
                     EIAEEEASLGSEEVALKTLQDEMARLIESLEAIKSQGEQARIQEQGLFLAYQQTSQQV
                     EELETLWKLQEEEIDRLSEGDWQADKENCQERLAAIASDKQNLEAEIEEIKSNKNAIQ
                     ERYQNLQEELAQARLLKTELQGQKRYEVADIERLGKELDNLNIEQEEIQRMLQEKVDN
                     LEKVDTDLLNQQAEEAKTQKTNLQQGLIRKQFELDDIEGQLDDIASHLDQARQQNEEW
                     IRKQTRAEAKKEKVSERLRHLQSQLTDQYQISYTEALEKAHELENLNLAEQEVKDLEK
                     AIRSLGPVNIEAIDQYEEVRNRLDFLNSQRDDILSAKNLLLETITEMNDEVKERFKST
                     FEAIRESFKVTFKQMFGGGQADLILTEGDLLTAGVEISVQPPGKKIQSLNLMSGGEKA
                     LSALALLFSIIRVKTIPFVILDEVEAALDEANVKRFGDYLNRFDKDSQFIVVTHRKGT
                     MAAADSIYGVTMQESGVSKIVSVKLKDLESIEG"
     gene            complement(21019..21717)
                     /locus_tag="VYO11_001225"
     CDS             complement(21019..21717)
                     /locus_tag="VYO11_001225"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HEV1595797.1"
                     /translation="MKELQTVLKNHFAIEFTDKKLLETAFTHTSYANEHRLLKISHNE
                     RLEFLGDAVLQLLISEYLYKKYPKKPEGDLSKLRAMIVREESLAGFARDCQFDQFIKL
                     GKGEEKSGGRNRDTILGDAFEAFLGALLLDKDVAKVKEFIYQVMIPKVEAGEFEMITD
                     YKTHLQELLQVNGDVAIRYQVISETGPAHDKVFDVEVLVEGKSIGQGQGRSKKLAEQE
                     AAKNAVEKGLDSCI"
     gene            complement(21900..21971)
                     /locus_tag="VYO11_001226"
     tRNA            complement(21900..21971)
                     /locus_tag="VYO11_001226"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(21936..21938),aa:Arg,seq:ccg)
     gene            complement(22035..23021)
                     /locus_tag="VYO11_001227"
     CDS             complement(22035..23021)
                     /locus_tag="VYO11_001227"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HEV1595798.1"
                     /translation="MLNEFPIFDYEDIQLIPNKCVIKSRAEADTSVTLGNHTFKLPVV
                     PANMQTILDENVAEQLAKGGYFYIMHRFDEAGRIPFIKRMHDQGLIASISVGVKDYEY
                     DFVRQLKTDAPEYITIDIAHGHADSVISMIQHIKKELPDTFVIAGNVGTPEAVRELEN
                     AGADATKVGIGPGKVCITKVKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIA
                     KSIRFGASMVMIGSLFAGHIESPGKTIEVDGEQFKEYYGSASQYQKGAYKNVEGKRIL
                     LPAKGHLQDTLTEMEQDLQSAISYAGGRQVADLKHVDYVIVKNSIWNGDASH"
     gene            complement(23196..24512)
                     /locus_tag="VYO11_001228"
     CDS             complement(23196..24512)
                     /locus_tag="VYO11_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001223073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrC family protein"
                     /protein_id="HEV1595799.1"
                     /translation="MRITDNQHKIIKEKFVEEYPKLSNPLLDRTLESLSQDERIFIFP
                     NDLTHTPDLDKDQKIFETVNQKIKTGNVIGFLGYGQERLTISSRFSDESNDHFLHYLL
                     NKVLHINLTSLDVALSREERLYQLLMYLFPKYLQAAIRKGLYKEYHRFSHNDSHVKGV
                     IDVRSHLKKNLPFTGNIAYTTREFTYDNPLMQLVRHTIEYIENQKSIGQGVLDNLSTS
                     RENVSEIVRVTPSYKLADRAKIIRGNQSKPIRHAYFHEYRNLQELCLMILNQEKHGLG
                     YQDQKIYGILFDVAWLWEEYVYTLLPKGFVHPRNKDKTDGISVFSVGKRKVYPDFYDR
                     ERKIVLDAKYKKLELTEKGINREDLFQLISYSYILKAEKAGLIFPSMEQSVNSEIGKV
                     AGYGAQLKKWSIRIPQNASSYSAFCKMMENSEENFKAIIDEEVGRK"
     gene            complement(24499..>26093)
                     /locus_tag="VYO11_001229"
     CDS             complement(24499..>26093)
                     /locus_tag="VYO11_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="McrB family protein"
                     /protein_id="HEV1595800.1"
                     /translation="LDQRFSKLKSDLYEIIKEGIRFNFENPIFDMKRSTNEFIGRSAM
                     VTKLLCIYTEGDPFFGVNINSQKEFWNHFVSQTNQGGPYLQNHKIIELVSKTYPELEP
                     SKLGTMLFEYSKLFMENKEDNSTMDSSNNFSHQLTQSLLKSPNLILRGAPGTGKTYLA
                     KEIAKELTDGNEDQIGFVQFHPSYDYTDFVEGLRPVSNGDGAIEFRLQDGIFKDFCQK
                     AKEPQLIGGQDNFDEAWDSYLEYINVAEEKEYITKTSYLSVNSRQNLSVNYDSGVPGW
                     SLPSKYVYELYKDKNYNKQEYYKSGGKTVLETLRKRFGLKDYVSPTEIDTDKKFVFII
                     DEINRGEISKIFGELFFSIDPGYRGEKGSVSTQYANLHETDEKFYIPENVYIIGTMND
                     IDRSVDTFDFAMRRRFRFVEVTAEGQVGMLDKELNIHAEEAKIRLRNLNAAIENVQEL
                     NSHYHIGPSYFLKLKDVDFDYELLWSDYIKPLLEDYLRGSYDEVETLETLKKAFDLTN
                     NEQKDQAVADDNEGDENDDADY"
BASE COUNT         7613 a         5804 c         4695 g         7981 t
ORIGIN      
        1 aaagagcaaa ctaggaagct agccgcaggt tgctcaaaac actgttttga ggttgtggat
       61 agaactgaca gagtcagtat catataccta cggcaaggtg aagctgacgt ggtttgaaga
      121 gattttcgaa gagtataaat cttattgatg aactgcttgc agtctgagaa aaaatgagct
      181 tggatattat ttccaaactc acttaaagtc aatttcaatc cactagaaca agcctagtac
      241 agttccatcg ctttcaacat ccatgttgag agctgctgga cgttttggaa gacctggcat
      301 ggtcataaca tcaccagtta aggcaacgat gaagcctgca cctaattttg gtaccaattc
      361 acgaatggta atttcaaagt tttctggtgc tccaagcgca tttggattgt ctgagaaact
      421 gtattgagtt ttagccatac agattggcaa tttgtcccaa ccgttttgaa cgatttgagc
      481 aatttgtgtt tgagctttct tctcaaagtt cactttgcta ccacgataga tttcagtgac
      541 aattttttca atcttttctt ggacagaaag gtcattatca tacaaacgtt tatagttagc
      601 tggattttca gcaattgtct taacaactgt ttcggcaagt gctactccac cttctgctcc
      661 atcagcccag acactagcca attcaactgg tacatcgatt gaggcacaga gttcttttaa
      721 ggctgcaatt tcagcttctg tatcagatac aaattcgtta atagctacaa ctgctggaat
      781 accgaactta cggatatttt caacgtggcg tttcaagtta gcaaaacctg cacgaactgc
      841 ctctacattt tcttcagtca gagcgtcttt agccacacca ccattcatct taagggcacg
      901 aagggttgcg acaataacaa ctgcatctgg agatgttggc aagtttggtg tcttgatatc
      961 aaggaatttc tcagcaccaa ggtccgcacc aaaaccagct tcagtaacag tgtaatcagc
     1021 caagtgaagg gctgttgtcg tcgccaaaac agagttacag ccatgagcga tattggcaaa
     1081 tggaccaccg tgtacaaagg caggtgtacc gtaaattgtc tgaaccaagt ttggcttaat
     1141 agcatccttc aaaatcaaag ccaaggcacc ctcaacctgc aaatcaccta cagaaacagg
     1201 cgtacggtca tagcgataac caataacgat attcgccaaa cgaagtttca agtcctcgat
     1261 gtccgttgcc aagcaaagaa ttgccatgat ttctgaagca actgtaatat caaaaccgtc
     1321 ctcacgtgga ataccgttta gaggaccacc aagaccaaca gtcacatggc ggagcgcacg
     1381 gtcgttcaag tccacaacgc gtttccagag gatacgacgt tgatcaattc ccagctcatt
     1441 cccttggtgc aagtggttgt caatcaaggc agaaagggca ttgttggcag ttgtaatagc
     1501 atgcatatct ccagtaaagt ggaggttgat gtcttccatt ggcagaactt gtgcataccc
     1561 accaccagca gcaccaccct tgatccccat gactggacca agagacggtt cgcggatagc
     1621 aatcatggtt ttcttgccaa tcttgttcaa ggcatccgca agaccaatgg taagcgtcga
     1681 ctttccttca cctgcaggtg ttgggttgat ggcagtaacc aagatcaatt taccgactgg
     1741 attgctctca actgcccgaa ttttatcaaa gctgagttta gccttgtact ttccgtacaa
     1801 ctccaaatcg tcgtaagaaa taccaagttt ctctacaaca tcaacaattg gcttcaactc
     1861 aatactctgt gcgatttcaa tatctgtttt cattcaaaat tcctctaacc tcttatatga
     1921 taattcatta tatcacaaaa caagattttt aacatcctaa aactctctaa acgttcgtaa
     1981 atatctctgt ttttaagact tttagagtcc tttcttaaat tttatatggc tttatagttt
     2041 gaaactataa taaatcttcg tttttaccaa aaatttatca ctttcatttt acttaccgct
     2101 tatttttgtg tacaatagtg ctatgaaaat tttagttaca tcgggcggta ccagtgaagc
     2161 tatcgatagc gtccgctcta tcactaacca ttctacaggt cacttgggga aaattatcac
     2221 agaaactttg ctttctgcag ggcatgaagt ttgtttaatt acgacaaaac gagctctgaa
     2281 gccagagtct catcctaacc taagtattcg agaaattacc aataccaagg accttctaat
     2341 agaaatgcaa gaacgtgttc aggattatca gatcttgatc cactcaatgg ctgtttctga
     2401 ctacactcct gtttatatga cagggcttga ggaagttcag gctagctcca atctaaaaga
     2461 atttttaagc aagcagaatc atcaggccaa gatttcttca actgatgagg ttcaggtttt
     2521 gttccttaaa aagacaccca aaatcatatc cctagtcaag gaatggaatc ctactattca
     2581 tctgattggt ttcaaactgc tggttgatgt taccgaagat catctggttg atattgcacg
     2641 aaaaagtctt atcaagaatc aagcagattt aatcatcgcg aatgacctga ctcaaatttc
     2701 agcagatcag caccgagcta tatttgttga gaaaaatcag cttcaaacag tccagactaa
     2761 agaagaaatt gcagaactcc tccttgaaaa aattcaagcc tatcattctt agaaaggaaa
     2821 actatggcaa acattctctt ggctgtaacg ggttcaatcg cctcttataa gtcggcagat
     2881 ttagtcagtt ctctaaaaaa acaaggccat caagtcactg tcttaatgac tcaggctgct
     2941 acagagttta tccaaccttt gtcactacag gtactctcac agaatcctgt ccacttggat
     3001 gtcatgaagg aaccctatcc tgatcaggtc aatcatatcg aacttggaaa aaaagcagat
     3061 ttatttatcg tggtacctgc aactgctaac actattgcaa aactagctca cggctttgcg
     3121 gacaacatgg taaccagtac agctctagcc ctaccaagtc atattcccaa actaatagct
     3181 cctgctatga atacaaaaat gtatgaccat ccagtaactc agaataatct gaaaacatta
     3241 gaaacctacg gctatcagct gattgctcct aaggaatccc tactagcttg tggagaccac
     3301 ggacgaggag ctttagctga cctcacaatt attttagaaa gaataaagga aactatcgat
     3361 gaaaaaacgc tctaatattg cacccattgc tatctttttt gctaccatgc tcgtgataca
     3421 ctttctgagc tcacttatct ttaacctttt tccatttcca atcaaaccga ccattgttca
     3481 tattcctgtc attattgcca gcattattta tggtccacga gttggggtta cacttggatt
     3541 tttgatggga ttacttagct tgacggttaa cacgattacg attctaccga caagctacct
     3601 cttctctccc ttcgtaccaa acggaaacat ctactcagct atcattgcca ttgtcccacg
     3661 tattttgatt ggtttaactc cttacttagt ctataaactg atgaaaaaca agactggtct
     3721 gattttagct ggggcccttg gttccttgac aaatactatc tttgtccttg gaggaatctt
     3781 cttcctattt ggaaatgttt ataatggaaa tatccaactt cttctggcaa ccgttatctc
     3841 aacaaattca attgctgaat tggtcatttc tgcaattcta tccctagcca ttgttccacg
     3901 actacaaacc ttgaaaaaat aaaaacaatc tccgctttca aacctgaagg tggagatttt
     3961 gctctataca gtttcttttt aatgaaatct ttactatagt aaaacgaaat aagaacagga
     4021 caaatcgatc aggacagtca aatcgatttc taacaatgtt ttagaagtag aggtgtacta
     4081 ttctagtttc aatccactat aacttttaac taaaaaatga tctataaacc caagtaaatt
     4141 cttgctttat tgtctggttt attgtaccat actagtgtat atgcagttaa aaaggagatt
     4201 cttgtgaata cacggaaaaa gacacaattt atgacaatga cagccctttt aacggctatt
     4261 gcgattttga ttccaattgt tatgcctttc aagattgtca ttccacctgc ttcctatact
     4321 ttggggagcc acatcgctat ttttatagcc atgttcttgt cgcccttgat ggcagttttt
     4381 gtcatcctag cctctagttt tggatttttg atggctggct atcccatggt tatcgttttt
     4441 cgggcctttt cccatatatc ttttggtgct ttaggagctc tttacctaca aaaattcccc
     4501 gataccctag ataaaccaaa atcttcctgg gttttcaatt ttgttttggc tgttgttcat
     4561 gcccttgctg aagtattagc ctgtgtcctt ttttacgcaa cttcgggtac caatgtagaa
     4621 aacatgttct atgttctatt tgtactagtt ggatttggca caattatcca tagtatggta
     4681 gactatacat tagcactagc tgtctataaa gtgcttcgaa aacgccgtta aaaggaaaag
     4741 ctatgacaaa agatcgcaaa caagccctgc tccaactctt gaaagaagct cctaaagccc
     4801 ttaatggcca aagtttggcg gaacattttc atgtcacacg tcaggtcatt gtgcaggaca
     4861 ttgcaatttt gagagccgat ggcgctccta tcctatccac caatcgtggc tacatctata
     4921 agcaaattga taccaatcct tatgttcaca aacttttcaa agtgaaacat gaagttgaag
     4981 aaatcggtca ggaactcctt gctattgtcg ataatggtgg gcatgtccag aataccttga
     5041 ttgaccatcc cgtttatgga gaaattgaaa ccttgcttaa actgtcttgt cgcagagatg
     5101 tgcaacattt tctagaacaa gtcgagcatt ctgactttag acctctatct gaattgacag
     5161 atggcatcca ttaccaccta gtcgaagccg aaacacaaca agacctccac tatatcgagg
     5221 aggccttgga tcagctaggt tatttagtaa aagactagaa gattttcttt tcccaatcgt
     5281 cttctgtacg gcgagggtag aaaaactctg acttgtcggg agcttccatc atttccatca
     5341 atggtagcat atcataggcc agatttaagt ttggaatctg gtctttttgc acccaagaaa
     5401 cttctccctc ttctgaagat tgaagggtac cagagaactc agtcgcctta taacaaatga
     5461 caatatagcg cccacctgta tctagtggcc aatttttaat gccgacaagt tgaggatttt
     5521 ggatagtcaa ccctgtttct tcgtagattt cacgaatgac agactccgca aaagcctcat
     5581 cattttctac atgacctcca ggaaaggcat aaccagacca gcgattgttt tcaggggcgc
     5641 gatactgcat caccacgcgc tgagtttcga ggtcttcaat cagacagata tttgttaaaa
     5701 ttgttaattg ggaacgggac ataaatttac tcgctttcta atttattaaa ttttcagact
     5761 tactaccaga gatattatct tttacttttt taaaattatt tagaatagaa caccattcgt
     5821 ttttccttta taggctttcc aagttcaagt attttttctt gtccatcaaa agtaaaaccc
     5881 attttttgat agaaagcaat ggcgcgcttg ttatctttca atacccataa gaaaatttca
     5941 gaaaaatgat taagagcagt caaagctgct ttcattaact tttgtgcgat accttttcca
     6001 taatagtctt ttaaaacata taaagcaata atttcaccag cttgaatagt ctcatcacga
     6061 aaattgccat aactgataaa accaaccacc ttcacgccat ccatcgcaat caatgtattt
     6121 tctggatact tttgactaaa gaatcgacat ctttctaatg tcattgtatc ctgaaattcc
     6181 gcaggcaaaa ggtcatcata agactctctc cacatttgcc agtgaacaag ggatttacct
     6241 tctatctctt taggagtttc cattgatttg ataataaccg tcatttattt tctcccagtc
     6301 ttctctcaaa ataccatatt taatactatc aaaatattta ccttgataat aacgaacttt
     6361 tggaatatga gcttcttttt tcattcttaa tttttcagca agtttcatca taccaagatt
     6421 ccctgaccaa gttgtcaaac ccagatgctc caactccaag taatcctgaa acgtcctatc
     6481 tatccactgc aacatagcaa ctttcccaat accagtgttc cagaattttt tatcataaat
     6541 accaattccc aattccatcc atcttgtttg tttacatacc caataacgcg aaacagtccc
     6601 aactagttta tcatcaacaa aaataccaag gcgatttgag ttgcttaaaa tggattctga
     6661 tttttgtagt tcgaattctt taaaatttga aaaatactga taatcatcat aatagggagc
     6721 atcatactgt ttccaaactg gattaagttg tgaataagcc atttcccata aagacatcaa
     6781 atcttctctc tttaactttc ttaaataaat catactattc ccctaatcca aggccttgac
     6841 ttccaacatc atatcacgga tctgagccgc cagttcaaag tcaagcactt cgacggcttc
     6901 ttgcatttgt ttttctagtt tcttgacgag ttcttttcgc tcttgtttgt tgaggctagt
     6961 gatgtcgact tccttgtcct cttccttagc aactgccttg gtcacagcaa tcaggtcacg
     7021 gatttctttc ttgattgtct gtggtacgat accatgctct tcattatagg ccatctgaat
     7081 tttccgacgg cgggcagttt catcgatagc acgttgcata gactgggtaa ccgtgtctgc
     7141 atacatgatg acatggcctt cactgttacg agcagcacgt ccaatagtct ggatgagtcc
     7201 acgttcgttg cgaaggaaac cttccttgtc agcatcgaga atagctacga ggctcacttc
     7261 aggaacgtca attccttcac ggagcaggtt aattccgacc aagacatcaa agacacccaa
     7321 gcgcaggtca cggataatct ccgtccgttc caaggtcttg atatccgagt gcatgtactt
     7381 aaccttgata cccatttcct tgaagtagtc ggtcaagtcc tctgccattt tcttggtcaa
     7441 agttgtgata aaggtacgct catttttttc aacgcgggca ttgatttcac ccaagaggtc
     7501 atcaatctgt cccatagtcg gacggacttc cacctctgga tccaagagtc ccgttggacg
     7561 aatgatttgc tcaatcactg tctcggtctg ttcattttca tagtcaccag gtgtcgctga
     7621 aacgtaaaca atctgatgaa cgtgactctc aaactcctcc cgacggagag gacgattgtc
     7681 caaagcagac ggcaaacgga aaccataatt aaccagcatt tctttacgag aacggtctcc
     7741 attgtacatg cccttgattt gccctatggt catatgactc tcgtcaatca taatcaagaa
     7801 atcatctggg aagaagtcga gaagcgtata aggaggctct ccttcgctcc gtccatccat
     7861 gtggcgagaa taattttcaa ccccattggt atagcccatc tcacgcaaca tttcgatatc
     7921 atactctgtc cgctgtttca aacgctgggc ttcaagcagt ttaccttcct tttcaaagac
     7981 agctaattgt tcttccaact cggcctgaat ctttgcaatg gcaacttcca tgtggtcgtc
     8041 attggtcaca aagtgtgtcg ctgggaaaat cgctaaatga tccacttctc ccaacacctg
     8101 acctgtcaga gcctcaactt cacgaatacg gtcaatttcg tctccaaaaa attctactcg
     8161 aaaggcatgt tcatctcggg aagctgggaa aatctctacc acatccccac gaacgcgaaa
     8221 tcttccgcgt tggaaatcaa tatcattacg ttcaaactga atatcgacca agtcattcaa
     8281 gagtttatca cgagaaatct ctagaccagg acggagacta acgacactat cagcgtattc
     8341 cttgggcgaa cccaaaccat agatacaaga aactgaggcc acaacaataa catcattacg
     8401 ctccaaaagg gctgaggtag ctgagtggcg aagcttgtca atctcgtcat tgacagaact
     8461 atccttctca atataggtat cgctagaagg gacataggcc tctggctggt aataatcata
     8521 gtaggatacg aaatactcaa ctgcattttc agggaaaaat tccttaaact ccccatagag
     8581 ctgaccagcc agagttttat tgtgggcaat aaccagagtt ggtttattga ctttagaaat
     8641 gacctgactc atagtatagg tcttccctgt tccagtcgcc cccatcagaa tctgagcttt
     8701 ttctcccccc tcaatgttat ccaccaactg ctcgatagct tggggttgat ctcctgatgg
     8761 ttgatatttt gatactagtt taaattgatt atctgtaatg tgattgatca taagaatcct
     8821 ctctccatgt gctattccta ttttagcata cttatagtat tttcacgaag aaaaggacgg
     8881 accgaagtca catcctttca ttttctttct ttaatttatt agcaagatag acaatcagca
     8941 gtagtaatac cagacttgtc ataatggaac cttctatgcc aaaagaacca cctgatagcc
     9001 aatcttgatt gccttgtggt aaaaaggtca tcagagacgt tcctgacggt tgaccactaa
     9061 ctaaaatccc aaagagatta ccctgagcaa aattccaagc accatgaata cctgcaacac
     9121 cccaaactgt atcagttttg agaaggtaaa gagccatggc aactccgaat aaaaagagat
     9181 ttactagagg atagaggggt gaggccagaa ttgcccatat gaagcagggt aaagaacagg
     9241 ctagatataa aaatagctag ttttagattg gttcttgagg ccaattgagg aagtagccaa
     9301 gcacgggcca ccacttcttc tgctgtcccc tgtaaaatcc aaaatgggat agtaaagacg
     9361 acaaaggcaa gagaataagg attcaagtga atggattcca aacgatattg acctaagagc
     9421 accaaaccta acaaggtcag aagaaaaagt gccagaccta gactaaatcc tttcagaaga
     9481 ttgctgagga aattctctct ataaaatccc aaggttcgaa taggtctttt ctcaactttt
     9541 cttgtccatc tgaacacagt gttaagaata aaaccaaagg ccagtaatcc taaaattaaa
     9601 cgaaagtcac ttgttttatc cgtcaagctc tgatgcaagg tctgcaagta gcttgcaaga
     9661 ttttgaccag cctctccaaa atttctagca agtccgatga gagctaacaa actaatacca
     9721 tataaagtat aagccacaaa ctctcctatg aagacaaaaa caaaggctaa caaggggctt
     9781 gtgtaaatgt ttaaactcat ttttgaagct tggaagtctt taaatattct tttgttcttc
     9841 atatccccgt cctcttttct tctatatata ctattattat agcacttttt aatagcaatt
     9901 caagaaaagg aaaaaatcaa tgttatattt tctgacacga aaaatataaa aatttgcctt
     9961 tttttacttt ttctgatata atgagagaat attcggaaaa ggagactaaa aatgaagaaa
    10021 aaatttctag catttttgct aattttattc ccaattttct cattaggtat tgccaaagca
    10081 gaaacgatta agattgtttc tgataccgcc tatgcacctt ttgagtttaa agattcagat
    10141 caaacttata aaggaattga tgttgacatt attaacaaag tcgctgagat taaaggctgg
    10201 aacattcaga tgtcctatcc tggatttgac gcagcagtca atgcggttca agctgggcaa
    10261 gccgacgcta tcatggcagg gatgacaaag actaaagaac gtgaaaaagt cttcaccatg
    10321 tctgatactt actatgatac aaaagttgtc attgctacta caaagtcaca caaaattagc
    10381 aagtacgacc aattaactgg caaaaccgtt ggtgttaaaa acggaactgc cgctcaacgt
    10441 ttccttgaaa caatcaaaga taaatacggt tttactatta aaacatttga cactggggat
    10501 ttaatgaaca acagcttgag tgctggtgcc atcgatgcca tgatggatga caaacctgtt
    10561 atcgaatatg ccattaacca aggtcaagac ctccatattg aaatggatgg tgaagctgta
    10621 ggaagttttg ctttcggtgt gaaaaaagga agtaaatacg aacacctggt tactgaattt
    10681 aaccaagcct tggctgaaat gaaaaaagat ggtagtcttg ataaaattat caagaaatgg
    10741 actgcttcat catcttcagc agtgccaact acaaccactc tcgcaggatt aaaagctatt
    10801 cctgttaagg ctaaatatat cattgccagc gattcttctt ttgcaccttt tgttttccaa
    10861 aattcaagca accaatacac tggtattgat atggaattga ttaaggcaat cgctaaagac
    10921 caaggttttg aaattgaaat taccaaccct ggttttgatg ctgctatcag tgctgttcaa
    10981 gctggtcaag ctgatggtat cattgctggt atgtctgtca cagatgctcg taaggcaact
    11041 tttgacttct cagaatccta ctacactgct aataccatcc ttggtgtcaa agaatcaagc
    11101 accattgctt cttatgagga tttgaaaggg aagacggtcg gtgttaaaaa cggaactgct
    11161 tctcaaacct tcctaacaga aaatcaaagc aaatacggtt acaaaatcaa aaccttcgct
    11221 gatggttcat caatgtatga cagtttaaac actggtgcca ttgatgccgt tatggatgat
    11281 gagcctgtcc tcaaatattc tatcagtcaa ggacaaaaat tgaaaacacc aatcgctgga
    11341 actccaatcg gtgaaacagc ctttgccgtt aaaaaaggca caaatcctga attgattgaa
    11401 atgttcaaca acggacttgc aaaccttaaa gcaaacggtg aattccaaaa gattcttgac
    11461 aaatacctag ctagcgaatc ttcaactgct tcaacaagta ctgttgacga aacaacgctc
    11521 tggggcttgc ttcaaaacaa ctacaaacaa ctccttagcg gtcttggtat cactcttgct
    11581 ctagctctta tctcatttgc tattgccatt gtcatcggaa ttatcttcgg tatgtttagc
    11641 gttagcccat acaaatctct tcgcgtcatc tctgagattt tcgttgacgt tattcgtggt
    11701 attccattga tgattcttgc agccttcatc ttctggggaa ttccaaactt catcgagtct
    11761 atcacaggcc aacaaagccc aattaacgac tttgtagctg gaacaattgc cctctcactc
    11821 aatgcggctg cttatatcgc tgaaatcgtt cgtggtggta ttcaggccgt tccagttggc
    11881 caaatggaag ccagccgaag cttgggtatc tcttatggaa aaaccatgcg taagattatc
    11941 ttgccacaag caactaaatt gatgttgcca aactttgtca accaattcgt tatcgctctt
    12001 aaagatacaa ctatcgtatc tgctatcggt ttggttgaac tcttccaaac tggtaagatt
    12061 atcatcgctc gtaactacca aagtttcaag atgtatgcaa tccttgctat cttctatctt
    12121 gtaattatca cacttttgac tagactagcg aaacgcttag aaaagaggat tcgttaatgg
    12181 caaaattaaa aattgatgta aatgatttac acaagcacta tggaaaaaat gaagtcctaa
    12241 aaggaattac gactaagttc tatgaaggag atgttgtttg tatcatcggt ccttcaggtt
    12301 ctggtaagtc aactttcctc cgtagcctca atcttttaga agaagtcact agcggtcaca
    12361 tcactgtgaa cggctatgat ttaactgaaa aaacaaccaa tgttgaccac gtccgtgaaa
    12421 atatcggcat ggtattccaa cacttcaacc tcttccctca tatgtctgta ttggacaaca
    12481 tcacctttgc tcctattgag cacaagttga tgactaagga agaagctgag gaattgggaa
    12541 tggagttgct tgaaaaggtt ggactagcag ataaagctaa tgccaatcca gatagcctat
    12601 caggtggtca aaaacaacgt gtggccatcg ctcgtggcct agcaatgaat ccagacatca
    12661 tgctcttcga tgaaccaact tctgcccttg accctgagat ggttggagac gtacttaacg
    12721 ttatgaagga attggctgag caaggcatga ccatgattat cgtaacccat gagatgggat
    12781 ttgctcgtca ggttgccaac cgcgttatct ttactgcaga tggcgagttc cttgaagacg
    12841 gaacacctga ccaaatcttt gataacccac aacaccctcg tctgaaagag ttcttagata
    12901 aggtcttaaa cgtctaaact caaactgtaa ggatttcctt gcagtttttc tacctcgtat
    12961 tggaattttt gatttttcgg aaaattatgt tagaattaag tttatgaaat gaggtttcct
    13021 catacctagc aagactagga ataaaaatag aaattaggta gctagatgtc atctaaggtt
    13081 attgttacaa ttttcggtgc gagtggagac ctggctaaac gcaagctcta cccttccctt
    13141 tttagactat ataaatccgg caatctttcc aagcactttg ccgttattgg aactgcccgt
    13201 agaccttgga gtaaggaata ttttgaatct gtagttgtcg agtccatcct tgatttggca
    13261 gatagtaccg agcaagccca agaatttgct agccacttct actatcaaag ccatgatgtc
    13321 aatgattcgg aacattatat tgctttgcgt caattacaag ctgagcttaa tgaaaaatac
    13381 caagctgaac acaataagct cttcttcttg tctatggcac ctcagttctt tggaaccatt
    13441 gccaaacacc tcaaatctga aaacattgtc gatggcaaag gttttgagcg cttgatcgtt
    13501 gaaaaaccat ttggtacaga ttacgcaact gcaagcaagt tgaatgacga actcctagca
    13561 acatttgacg aagaacaaat tttccgtatt gaccattatc ttggtaagga aatgatccaa
    13621 agcatctttg cagttcgctt tgcaaacttg atttttgaaa acgtttggaa caaggatttt
    13681 atcgacaatg ttcaaattac ctttgcggag cgcttgggtg tagaagaacg tggtggctac
    13741 tatgaccaat ccggtgccct ccgtgacatg gtccaaaacc acactctaca acttctttcg
    13801 ctcctcgcca tggacaaacc agcaagcttc acaaaagacg agattcgtgc tgaaaagatt
    13861 aaggtcttta aaaacctcta tcatccaact gatgaagaac tcaaagaaca ctttatccgt
    13921 ggacaatacc gctctggtaa gattgatggc atgaaataca tctcttatcg tagcgaacca
    13981 aatgtgaatc cagaatcaac aactgaaacc tttacatctg gtgccttctt tgtagacagc
    14041 gatcgattcc gtggtgttcc tttctttttc cgtacaggta aacgactgac tgaaaaagga
    14101 actcatgtca acatcgtctt taaacaaatg gattctatct ttggagaacc acttgctcca
    14161 aatattttga ccatctatat tcaaccaaca gaaggcttct ctcttagcct aaatgggaag
    14221 caagtaggag aagaatttaa cttggctcct aactcacttg attatcgtac agacgcgact
    14281 gcaactggtg cttctccaga accatacgag aaattgattt atgatgtcct aaataacaac
    14341 tcaactaact ttagccactg ggatgaggtt ggtgcgtcat ggaagttgat tgaccgtatt
    14401 gaagagctct gggccgaaaa tggtgcccca cttcatgact ataaagctgg aagcatggga
    14461 cctcaagcca gctttgacct acttgaaaaa ttcggtgcca aatggacttg gcaaccagat
    14521 atcgcctatc gtcaagatgg tcgcttagaa taaaaaaatt tcctgcaagt ttatgccttg
    14581 caggattttt gcttctgatt agattaaacc ttccaagaga cctttcatga agttttctga
    14641 gttaaactct ccaatatcat cgattttttc accaaaacca atcaatttta caggaatatt
    14701 gagttcttca cgaatggcta gaaccacacc tcctcgagca gttccatcaa tcttagtcaa
    14761 aacaattccc gttaaaggtg tgattttcga aaattctttg gcctgtacta gggcattttg
    14821 acctgttgat gcatcaagtg ccaagaaggt ttcatgtggt gcttctggca caacacgttt
    14881 gataatacga ccaatctttt ccaactcagc cataaggtta tccttatttt gcagacgacc
    14941 agcagtatca atcatgagaa tatcgatacc ttcagccacg gcacgttcca taccatcaaa
    15001 gaccacgctg gctggatcag ctttttcagg tccagttact actggaacat ctactcgtcg
    15061 gccccattca gctagctgag ctactgcacc cgcacggaag gtatctgctg caaccagcat
    15121 gaccttctta ccagctcgtt tgtagcggtg agctagtttt ccgatagaag ttgttttccc
    15181 aacaccattc acaccaacaa agagcataac tgtcaagtta tcttggaagt ggatgctttc
    15241 atcgtagcta ccatcctttt cataaagctc aaccaatttc tcaatgatga cacgacgaag
    15301 tgcatcaggt ttcttggcat tttcaagctt ggcttcgtaa cgtagttcct ccgttaagtt
    15361 agaagcgact tggacaccaa catcactcat aatcaacagt tcttccagtt cctcgaaaaa
    15421 ttcttcgtca acagagcgga agttagcaaa gaaggcattc aagcgggcac cgaaacctgt
    15481 gcgagttttc ttaagactgc ggtcatattt ttcctgaaca gtttcttctg tttgaggcct
    15541 ttctgcttca agaacttcag aattattttc ttctacagtc tctagaaact cagtattccc
    15601 ttcttctgag tgtggaaatt ctttgacttc tttttgagaa acttctataa ctggctctaa
    15661 atccagactt tcttcaactg tgtcttggat ttcctcttct tggaacacag cttgttcaac
    15721 aatttcaacc tctgcttctt cctgagaaac ttcctcaact tctgtgaagg taggatcaac
    15781 atcttcagac aaatcaagat tttccagagc ttcttttaca acttcttcga ttttaggttc
    15841 ttcttttttt ccgaatagac ggtcaaacaa tcccatatct tagttctcct ttagcacata
    15901 ttcttcgata gcccaggcga cagcttcctc atcgttggtc atcggcgtca ctacatttgc
    15961 ggctgccttt acttcaggaa cagcgttttg catggcaaca ccgagccctg cccattcaat
    16021 catagagagg tcattggcct cgtcaccaca ggccatcact tgactttgat caattccaag
    16081 atggctaatt agttttgcca aacctgttgc tttatgaaca ttctttggtg accattctag
    16141 caacatttca cgtgatttaa agatttcata ttggtcaaac aattctggag aaatcttctg
    16201 aatggctgca tccaagggtt cttgagcaaa ggcggtcacg catttgttgt aggtcatttg
    16261 attagacagg tcttcaaaat caactggaac aaaagtcaaa gctggattga atttggcata
    16321 aagactttct tggtccgatt gaatttgata aacagttcct tctgagatag cgtcaagagg
    16381 cagtgataat ttctctgttt cttcatacaa gcgtgccaca tcatcatatg aaaagactgt
    16441 cttatcaagg atttcacctg tatttttctg aaccaaacca ccattaaaag taatggtata
    16501 ctcatcttca tggccgtcag tccctaactc atggagaaag aagtccatgg cttttaaggg
    16561 acgaccagtt gtcaatacga ccttgatacc acgatcacgc gcagctttca aggtttcctt
    16621 ggtacgatcc gtcagccttt tatcagtagt cagcaaggtc ccgtccaagt ccaatgcgat
    16681 taattttata tctgccatta taagccctcc atataagcta taaccgactg gtccttatgg
    16741 tgaccaatca cagtctttgc taattctaaa atttcaggtc gtgcattttc aggagctaca
    16801 ggatgtccca caacctgcat catatgtaag tcattaagat tgtctccaaa agccatgacc
    16861 tgatccattg tgataccaag ttttttaact aattcaacaa tggccactcc cttatcgaca
    16921 tagtccagaa caatatcaat ggactcaaag ccagttgtca tggccttaac accaggaacg
    16981 ttttcgttta cccaagcctc cccatcttcc agcgtttctt ctgtgaagtt ggttgtaaat
    17041 ttgaaaatgt catctgtgat atcttccaaa ctcgctactt tttggatatt ttcattatag
    17101 tgctgactca ctttcaaata ggtctcatca accgtatcta gaacatatga acccttctta
    17161 cccgtcaaga gcagtttatt gatatctaca taaggtgaag ttttcagctt ttcaaaagtt
    17221 gccagataaa agtcacgaga catggtcact tcatacaagt cctgaccttg atattcgacc
    17281 aaactgccat tttccgcgat gaaaataatg tcatcacgta catcagcaaa taatttttcc
    17341 agagacagaa atccccgacc cgaagccacc gcaaagtaaa tccctttttc cttgtaggaa
    17401 gccaagagag acttgagacg atccatatca aagcgtccat tcccatctag gaaggttccg
    17461 tccatatccg ttgctactag tttaattgtc atccttcaat actttctaaa tcttttaact
    17521 taactgaaac aatctttgaa acacccgatt cttgcatggt cactccatag atggaatcag
    17581 ccgctgccat ggttccctta cggtgggtta cgacgataaa ctggctgtcc ttgtcaaagc
    17641 ggttgaggta atccccaaaa cgtttaacat tggcttcatc cagcgcagct tccacctcat
    17701 ccaagatgac aaaaggaatg gtcttgacac gaataatgga gaaaagcaag gcaagagccg
    17761 atagagcttt ttcaccacca ctcatgaggt taagcgactg gattttctta cctggaggtt
    17821 gaacagaaat ctccacacca gctgttaaaa ggtcgccctc agtcaatatc aagtctgcct
    17881 gacctccgcc aaacatctgc ttgaaggtca ctttaaagga ctcacgaata gcttcaaagg
    17941 ttgatttaaa gcgttccttg acctcatcat tcatctctgt aatggtttca aggagcagat
    18001 ttttcgctga caaaatatca tctcgctgac tatttagaaa gtccagacgg ttgcgaactt
    18061 cttcgtactg gtcaatagct tctatattga cagggcccag tgagcgaata gccttctcta
    18121 aatccttaac ttcttgctct gccagattga ggttttccaa ttcatgcgct ttttctagag
    18181 cttcagtata gctaatctgg tactggtctg ttaattgact ttgtagatgg cgcaagcgct
    18241 cgctgacctt ttctttcttg gcttcagcac gtgtttgctt gcgaatccac tcctcattct
    18301 gctggcgagc ctgatccaaa tgactagcaa tatcatccag ctgcccttct atatcatcca
    18361 actcaaactg cttgcgaatc aaaccttgtt ggagatttgt tttctgagtt ttggcttctt
    18421 cggcctgctg attgagcaaa tccgtatcaa ctttctcaag attgtcaact ttttcttgga
    18481 gcatgcgctg gatttcttct tgttcgatat taagattatc caattccttg cctaaacgct
    18541 caatatcagc aacttcataa cgtttttgcc cttgcagttc tgtcttaagc aaacgagctt
    18601 gcgctagctc ttcctgcaag ttttgatagc gttcttggat ggcatttttg ttagacttaa
    18661 tctcttcaat ctcagcttcc agattttgct tgtcactggc gattgcagca agacgctctt
    18721 ggcagttttc cttatccgct tgccaatctc cctcggaaag acgatctatt tcctcttctt
    18781 ggagtttcca aagagtttct agctcttcaa cttgctgact agtttgctga taagcgagga
    18841 acaagccttg ctcctgaata cgtgcctgct ctccttgaga tttaatagct tctaatgact
    18901 cgatcaatct ggccatctca tcttgcaagg tcttcaaagc cacttcttct gaacccaagc
    18961 ttgcttcttc ttcagcaatt tctttttgta attgctccag ttctggcttg atgaagatac
    19021 tgttgttctg acgattggct ccacctgcat aggaaccacc tgtacgaagc tctgtcccat
    19081 ccaatgtcac catgcgaacc tgataacgaa cttgtcgagc agcttcacgc gcatgttcta
    19141 cggtatcaaa gatagccgtc gtagctagca agttcttgaa aatggcttcc agtctagtat
    19201 cgaaagtaac taactcatct gccatcccaa ggaaacctgg gcttacagcg atagcatctt
    19261 ggttctgact agaaatcgta cgcgccttaa tagtggtcaa aggaagaaag gttgcacgac
    19321 cggctctgtt tcgtttgagg aaatcaatgg ctttggttgc cgcattctca tcttctacaa
    19381 taatgtgctg actactcgct ccaagtgcaa tttctagggc agtttgataa tgcatatcaa
    19441 aggtcagatg ctcactgact gcaccaataa tcccacctag gcgatctttt tcttggagaa
    19501 cactcttaac acctgcataa aagttactat gatttctcag gatattttcc aaactttgag
    19561 ctctggcctg cttgtttttg agattatcca gacggtcaaa gagttggctt tgttgagctt
    19621 gataggaagt tttctgctcc tcttgctcct tggcaatagc ttggtagtca gccaataatt
    19681 tctgaacctg ctccttggca gtttcaagct cttccttttg ctgactagcc ttctctttag
    19741 ctatagccaa ttgctctttc agcttttcta gttgatctgc ttgtttttga gaaagctgac
    19801 gactattttc caactcattc tcaatacggg tcaactggtt tgagacatcc gcttcttctt
    19861 gtaaaagagc tacaaagcgt tcacgtaaga gctcaatcat ctgatcagga tcgtctgaga
    19921 aagccagcaa ttcagcttct aaacgattga gtttttgatt attttggact agatttccct
    19981 ctaacagagc taaagagctt tctttatcag acttttcttt gctgagtgaa tttctcttat
    20041 cctccaaagc agccaaacga gcttgtgcct cctgttgatt caaggccact tgctcggact
    20101 ccagttttga tagggctaat tttctttcta aatcactaat cagactagtc aagtccatca
    20161 aactgccttg gtctttggcc atttcagcct gtaaatcttg gcgttgcttt ttaagagttt
    20221 gattttcttc ttctaatttt tcacgctttt ggtaataact catcaagagt tcttgaacct
    20281 gagccaactc ttcttctgtc gactctagtt cagccttatt ttccttgatt tgagcaacca
    20341 gaacgtctaa ataaatagcc ttacgttgtc cttccaagtc taaaaactta cgggcattct
    20401 cagcttgctt ctcaagaggc ttgatttgat tatccaactc gtagataatg tcctctaagc
    20461 ggtccagatt atcctgagtt tgctgcagtt tactctcggt ttcttttctg cgagtcttgt
    20521 attttaaaac tccagcagct tcttcaaaaa tagatcgtcg ttcctcaggc ttggaattaa
    20581 aaatctcctc aaccttccct tgggaaatga tggaaaagga atctcgtccc aaacctgtgt
    20641 ccaagaagag atcatgaata tcacgaagac gaactttctt gccgtcaatc ttgtattcgc
    20701 tatctccact acgatagata tggcgttcca ccctgatttc ttgacctgca tccttgataa
    20761 atccgtcatg attatccaga gtcacaacta cagaagcata attgagcggt ttgcgacttt
    20821 cggttccagc aaagatgaca tccggcatct tgcccccacg gagactcttg acactagact
    20881 cccccaaagc ccaacgcaga ctttctgtaa tattggactt tccagatcca ttgggtccaa
    20941 caactgccgt cacaccttgg tcaaaaacga ccttggtctt atcagcaaaa gacttgaacc
    21001 cctgaatttc gatttccttt aaatacatga atccagcccc ttctcaacgg catttttggc
    21061 agcttcctgc tctgctaatt tcttagaacg accttggcct tgaccgatgc tcttaccttc
    21121 aacaagaact tctacatcaa agaccttatc gtgagcaggc cctgtttcag aaatcacctg
    21181 ataacgaata gccacatcac cattgacctg aagcaactct tggagatggg ttttatagtc
    21241 tgtaatcatc tcaaattcgc ctgcttcaac cttaggaatc atgacttgat agataaattc
    21301 cttgaccttg gccacatcct tatccaaaag aagggcacca agaaaggctt caaaggcatc
    21361 accaagaatg gtgtcacgat tgcgaccacc agatttttct tcccctttac ccaacttgat
    21421 aaactggtca aactggcaat cacgcgcaaa accagctaaa ctctcctcac ggacaatcat
    21481 agcacggagt tttgataggt caccttcagg ctttttagga tattttttat acagatattc
    21541 tgaaatcaat aactgtagaa cagcgtctcc taaaaattcc aagcgttcat tatgtgaaat
    21601 ttttaagagg cggtgctcat tggcataact cgtatgagta aaggcagttt ccagtaactt
    21661 tttgtctgta aattcgattg caaaatggtt ctttagtaca gtttgtaatt ctttcatacc
    21721 aacctctttc taactgataa tagtcctttt tattatatca aaaaaagccc cctgagtcac
    21781 tctaaaacgg gactggaaag catttgggaa ttctttagac agagattctc agttttagcg
    21841 gcaaatttgg gtcaggataa agaaaaaagc cctattaaag gctttttagg atgtttacat
    21901 ccaccctgag ggaatcgaac ccccatctca agaaccggaa tcttacgtga tatccattac
    21961 actaagggtg gaaacttgtt ttattataac agaaatttgc tctaataaca agttttttgg
    22021 tcaaagaccc cgtcttagtg ggaagcatcc ccattccaga tggagttttt cacgatcaca
    22081 taatcaacgt gtttaaggtc agcaacctga cgtccacctg cataagaaat agcactttga
    22141 aggtcttgtt ccatctcagt taaagtgtct tgcagatgac ctttagcagg aagcaagata
    22201 cgtttgcctt ccacattttt gtaagcacct ttttgatatt gtgaggctga accataatat
    22261 tctttgaact gttcaccatc gacttcaatc gttttccctg gactttcaat gtgtcctgca
    22321 aagagggaac caatcatgac catgctagca ccgaagcgga tagacttggc aatatcaccg
    22381 tgagtacgaa ttcctccatc agcgataatc ggtttacgcg cagccttggc acaccagcgt
    22441 agagcagcca actgccaacc acctgtacca aaaccagtct taaccttggt gatacaaacc
    22501 ttaccaggac cgattccgac cttagtagca tccgcaccag cattttccaa ttcacgcaca
    22561 gcttctggtg ttcccacatt tccagcaatt acaaaggtat ctggcaattc tttcttgatg
    22621 tgttgaatca tagaaatcac gctatccgca tgaccatgag caatatcaat agtgatatac
    22681 tcaggagcat cagtcttgag ctgtctaacg aaatcatact catagtcctt aacaccgaca
    22741 gatatggaag caatgagccc ttgatcgtgc attcgtttaa taaaaggaat gcgtcctgcc
    22801 tcatcaaaac ggtgcataat gtagaagtaa ccacctttag ccagttgctc tgctacattt
    22861 tcatccaaaa tcgtctgcat attcgctggc acaacaggta gtttaaaggt gtgatttcct
    22921 aaagtgacac ttgtatccgc ttctgcacgg cttttaatga cacatttatt tggaatcaat
    22981 tgaatatctt cgtaatcaaa aattggaaat tcatttaaca tatcgatgtc tcgtttcttt
    23041 tgtaatgacc tacctatgct ctcgcatcac tacgcctttt ccgacgtttc cttaatttat
    23101 tataaaccaa agtacagttt ttgtcaaatt attttatgaa ttaaaatata tcgttcgggt
    23161 tttgcttgtg ttaaaaataa aagaaagagg ggaaattatt ttctccccac ttcttcatca
    23221 ataatcgctt taaaattttc ttctgaattt tccatcattt tacaaaatgc actataggat
    23281 gaggcattct gagggattcg aatagaccac ttcttcaatt gagctccata gccagctact
    23341 tttcctattt cactatttac tgactgctcc atactaggaa aaatcagtcc agccttctca
    23401 gcttttaaaa tataagaata ggaaatcagc tggaataagt cctcacggtt gattcctttt
    23461 tcagtcaatt ccagtttttt atattttgca tctagaacaa tctttcgttc tctgtcataa
    23521 aaatctggat atacttttcg tttcccaaca gaaaatactg aaattccatc cgtcttatcc
    23581 ttatttctgg gatgtacaaa accttttggc aacaaggtgt aaacatactc ttcccaaagc
    23641 caggcaacat caaagagaat accatagatt ttttgatctt gataccctaa accgtgcttt
    23701 tcttggttta ggatcatcag acaaagttct tgtaagtttc tgtactcgtg aaagtatgca
    23761 tgacgtatag gtttagattg atttccccga ataatcttag cacgatcagc tagtttataa
    23821 gagggcgtta cacgcacgat ttcagatacg ttttcacgac tagttgagag attatctagt
    23881 accccttgac caatgctttt ctgattctca atgtattcaa tagtgtgacg gaccaactgc
    23941 atgaggggat tatcataggt gaactctctc gttgtgtagg caatatttcc cgtgaaagga
    24001 agatttttct tgagatggct tcttacatca atcactccct taacatgact gtcgttatga
    24061 gaaaatcgat gatattcctt ataaagacct tttcgaatag cagcttgtag atacttgggg
    24121 aagagataca tcaaaagttg ataaagcctc tcttcacgag acaaagcaac atctaaacta
    24181 gtgagattga tatgaagaac cttgtttaag agataatgca aaaaatggtc attactctca
    24241 tcagaaaatc gtgaggaaat cgttaatctt tcctgaccat atccaagaaa accaatcacg
    24301 ttccctgtct taattttctg attgactgtt tcaaaaatct tttggtcctt atccaaatca
    24361 ggagtatgag tcaaatcatt tggaaaaatg aaaatacgtt catcttggga tagactttcc
    24421 aaggttctgt ctaaaagagg attgcttagt ttaggatatt cttcaacaaa tttttcttta
    24481 ataatcttgt gttgattatc agtaatccgc atcatcgttt tcatcgcctt cattgtcatc
    24541 agctactgcc tgatcttttt gctcattatt tgtcagatca aatgcttttt tcaaagtttc
    24601 caaagtttca acctcatcat aagaacctcg caagtagtct tctaggagag gcttaatata
    24661 atcagaccag agtaattcat agtcaaaatc tacatccttc aacttaagaa aataacttgg
    24721 tccaatatga taatgactgt ttaattcctg aacattttcg atagcagcgt tcaagtttct
    24781 tagacgaatt tttgcttctt ctgcatggat attcaactct ttatccaaca tgccaacttg
    24841 accctcggca gtaacttcaa caaaacgaaa acgacgacgc atagcaaaat caaaggtatc
    24901 cactgaacga tcaatatcat tcatagttcc gatgatgtaa acattttcgg ggatatagaa
    24961 cttttcatca gtttcgtgta gatttgcata ttgggtagaa acacttcctt tttcaccacg
    25021 atagccaggg tcgatagaga aaaagagttc gccaaaaatc ttagaaatct ccccacgatt
    25081 gatttcatcg atgatgaaga cgaatttctt atcagtatca atttctgttg gggaaacata
    25141 gtctttcaaa ccaaatctct ttctcaatgt ttctaggaca gtttttccac cacttttgta
    25201 gtattcttgc ttattataat ttttatcttt atacaactcg taaacatatt tgctaggtag
    25261 tgaccatcct ggaacaccac tatcataatt tactgacaaa ttttgtctac tattaacaga
    25321 taagtaagat gtttttgtta tatattcttt ttcttcagca acatttatat attctaagta
    25381 agaatcccaa gcctcatcaa aattatcttg tcctccaatc aattggggtt cttttgcttt
    25441 ctgacaaaaa tctttaaaaa taccgtcctg tagcctaaac tcaatagctc catccccatt
    25501 tgatactggt cttaaacctt ctacaaaatc cgtataatca taggatgggt gaaattgtac
    25561 aaatccgatt tggtcttcgt tgccatccgt taattctttg gcaatttctt tagcaagata
    25621 agtctttcct gtgccaggag caccacgaag gataaggttt ggagacttta atagagattg
    25681 agttaattga tgactaaaat tgtttgatga atccattgta ctattgtctt ccttattttc
    25741 cataaaaagc ttagaatact caaaaagcat agttcctaat ttcgatggct ccaactcagg
    25801 ataagttttg gacaccagtt caattatttt atgattttgc agataaggtc caccttgatt
    25861 tgtctgagaa acaaagtggt tccaaaattc tttctgacta ttaatattta caccaaagaa
    25921 aggatctccc tcagtataga tacaaagtaa ttttgtcacc atagcagaac gaccaataaa
    25981 ttcatttgtt gatcttttca tatcaaaaat aggattttca aagttaaaac gaataccttc
    26041 tttgataatt tcatacaaat ctgattttaa ttttgaaaat cgctgatcca act
//
LOCUS       DAVLXH010000027        25562 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00028199
            SAMN33607166-rid17955573.denovo.027, whole genome shotgun sequence.
ACCESSION   DAVLXH010000027 DAVLXH010000000
VERSION     DAVLXH010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607166
            Sequence Read Archive: SRR23725544
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25562)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25562)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721421.1
            Genome Coverage       :: 115x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:42:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,210
            CDSs (total)                      :: 2,161
            Genes (coding)                    :: 2,023
            CDSs (with protein)               :: 2,023
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 73 of 138
            Pseudo Genes (incomplete)         :: 60 of 138
            Pseudo Genes (internal stop)      :: 40 of 138
            Pseudo Genes (multiple problems)  :: 31 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25562
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607166-rid17955573.denovo.027"
                     /strain="AUSMDU00028199"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1349"
     gene            complement(127..276)
                     /locus_tag="VYO11_001230"
                     /pseudo
     CDS             complement(127..276)
                     /locus_tag="VYO11_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007895229.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
     gene            complement(430..2061)
                     /gene="rlmD"
                     /locus_tag="VYO11_001231"
     CDS             complement(430..2061)
                     /gene="rlmD"
                     /locus_tag="VYO11_001231"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000914584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HEV1595801.1"
                     /translation="MLKKNDIVEVEIVDLTHEGAGVAKVDGLVFFVENALPSEKILMR
                     VLKVNKKIGFGKVEKYLVQSPHRNQDLDLAYLRSGIADLGHLSYPEQLKFKTKQVKNS
                     LYKIAGIADVEVAETLGMEHPVKYRNKAQVPVRRVNGVLETGFFRKNSHNLMPLEDFF
                     IQDPVIDQVVVALRDLLRRFDLKPYDEKEQSGLIRNLVVRRGHYSEQIMVVLVTTRPK
                     VFRVDQLIEQVIKQFPEIVSVMQNINDQNTNAIFGKEWRTLYGQDYITDQMLGNDFQI
                     AGPAFYQVNTEMAEKLYQTAIDFAELKKDDVIIDAYSGIGTIGLSVAKHVKEVYGVEL
                     IPEAVENSKKNAQLNNISNAHYVCDTAENAMKNWLKDGIQPTVILVDPPRKGLTESFI
                     KASAQTGADRIAYISCNVATMARDIKLYQELGYELKKVQPVDLFPQTHHVETVALLSK
                     LDVDKHISVEIELDEMNLTSAESKATYAQIKEYVWNKFELKVSTLYIAQIKKKCGIEL
                     REHYNKSKKDKQIIPQCTPEKEEAIMDALRHFKMI"
     gene            complement(2135..3109)
                     /locus_tag="VYO11_001232"
     CDS             complement(2135..3109)
                     /locus_tag="VYO11_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1002 domain-containing protein"
                     /protein_id="HEV1595802.1"
                     /translation="MRKKLFLTSAAVLWAVTAMNSVHAATDVQKVIDETYVQPEYVLG
                     SSLSEDQKNQTLKKLGYNASTDTKELKTMTPDVYSKIMNVANDSSLQLYSSAKIQKLG
                     DKSPLEVKIETPENITKVTQDMYRNAAVTLGVEHAKITVAAPIPVTGESALAGIYYSL
                     EANGAKVPQANKDLAQEELKALSDINAENKDKSGYDANKLNVALADIKSGLAKAKESK
                     GNLTEEDIRKIVEDTLKNYKLDQVITGNQINIIINFALNLSKSDILSNADFTKTLNDL
                     KQSIVSQAGDSFKNINLNFDADKALEDGGNFLSSLWQALVNFFKSFGS"
     gene            complement(3183..3797)
                     /gene="pmp23"
                     /locus_tag="VYO11_001233"
     CDS             complement(3183..3797)
                     /gene="pmp23"
                     /locus_tag="VYO11_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000476388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall hydrolase Pmp23"
                     /protein_id="HEV1595803.1"
                     /translation="MFKRIRRVLVLAVFLFAGYKAYRVHQDVKQVMTYQPMVREILSE
                     QDTPANEELVLAMIYTETKGKEGDVMQSSESASGSTNTINDNASSIRQGIQTLTGNLY
                     LAQKKGVDIWTAVQAYNFGPAYIDFIAQNGKENTLALAKQYSRETVAPLLGNTTGKTY
                     SYIHPISIFHGAELYVNGGNYYYSRQVRLNLYIIKCFTLFSTSG"
     gene            complement(3797..4771)
                     /locus_tag="VYO11_001234"
     CDS             complement(3797..4771)
                     /locus_tag="VYO11_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HEV1595804.1"
                     /translation="MDIYIKKAIIHQFSPDDTELFLADKFLNITPKIEEYLRKKIEHV
                     YSDEAKTGIFEEENPFFNHITDDLLETSVTLANLWKEEFSISENLKTNDLIFVQFSKE
                     GVEHFAFLRIALRETLTHLGGEVDNPIKLTQNNLPGFGTGADEALVVNLQSSKYHLIE
                     KRIKYNGTFLNYFSDNLLAVAPKISPKKSIKELEKTAQRIAESFNTDDFQFQSKVKSA
                     IFNNLEESNELSPEKLANDLFDNNLTARLSFIDQVKEAVPEPVQFDEIDVSRQLKKFE
                     NQKLSLSNGIELIVPNNVYQDAESVEFIQNENGTYSILIKNIEDIQSK"
     gene            complement(4779..6035)
                     /locus_tag="VYO11_001235"
     CDS             complement(4779..6035)
                     /locus_tag="VYO11_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HEV1595805.1"
                     /translation="MIFDKDDFKAYDADLWNAIAKEEERQQNNIELIASENVVSKAVM
                     AAQGSILTNKYAEGYPGRRYYGGTDVVDVVETLAIERAKEIFGAKFANVQPHSGSQAN
                     CAAYISLIEPGDTVMGMDLASGGHLTHGAPVSFPGQTYNFVSYSVDPETELLDFDAIL
                     KQAQEVKPKLIVAGASAYSQIIDFSKFREIADAVGAKLMVDMAHIAGLVAAGLHPSPV
                     PYAHITTTTTHKTLRGPRGGLILTNDEELAKKINSAIFPGIQGGPLEHVVAAKAVSFK
                     EVLDPAFKEYAANVIKNSKAMADVFLQDPDFRIISGGTENHLFLVDVTKVVENGKVAQ
                     NLLDEVNITLNKNSIPYETLSPFKTSGIRIGAAAITARGFGEEESRKVAELIIKTLKN
                     SENEAVLEEVRSAVKELTDAFPLYEE"
     gene            complement(6097..6528)
                     /locus_tag="VYO11_001236"
     CDS             complement(6097..6528)
                     /locus_tag="VYO11_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000942930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1595806.1"
                     /translation="MLRDLQETDVKAICDINQEALGYTFSPEETASQLARLSQDSHHF
                     LLGYEDAANHVLLGYVHAEVYESLYSKAGFNILALAVSPQAQGQGIGKSLLQGLEQEA
                     KRCGYGFIRLNSANHRLGAHAFYEKVGYTCDKMQKRFIRIF"
     gene            complement(6530..7129)
                     /locus_tag="VYO11_001237"
     CDS             complement(6530..7129)
                     /locus_tag="VYO11_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HEV1595807.1"
                     /translation="MDRIRQELENGGAVILPTETVYGLFAKALDEKAVDHVYQLKRRP
                     RDKALNLNVASLEDILHFSKNQPAYLQKLVETFLPGPLTIILEANDRVPYWVNSDLAT
                     IGFRMPSHPITLDLIRETGPLIGPSANISGQASGVTFDQILKDFDQEVLGLEDDAFLT
                     GQDSTIVDLSGDKVKILRQGAIKREDILARLPEISFEEA"
     gene            complement(7116..7955)
                     /gene="prmC"
                     /locus_tag="VYO11_001238"
     CDS             complement(7116..7955)
                     /gene="prmC"
                     /locus_tag="VYO11_001238"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000761890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HEV1595808.1"
                     /translation="MKLAQLFSNFEEELIRQGEEAESLSFVYRSLKNLSFTDFIFALQ
                     QEVTTEEEKQFVEDIYQQLAAHKPAQYIIGQADFYGMHLKVDERVLIPRPETEELVEL
                     ILTENLETNLSVLDIGTGSGAIALALAKNRPDWSVTAADVSQEALDLASENAKNQNLQ
                     IFFKKSDCFTEISEKYDIIVSNPPYISREDESEVGLNVLYSEPHLALFADEDGLAIYR
                     RIAEDAKDYLKDGGKIYLEIGYKQGQSVPELFRKHLPEKKVRTFKDQFGQDRMVVVDD
                     GQD"
     gene            complement(7955..9034)
                     /gene="prfA"
                     /locus_tag="VYO11_001239"
     CDS             complement(7955..9034)
                     /gene="prfA"
                     /locus_tag="VYO11_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001028822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HEV1595809.1"
                     /translation="MNIYDQLQAVEDRYEELGELLSDPDVVSDTKRFMELSKEEASTR
                     DTVTAYREYKQVLQNIVDAEEMIKESGGDADLEEMAKQELKDAKAEKEEYEEKLKILL
                     LPKDPNDDKNIILEIRGAAGGDEAALFAGDLLTMYQKYAEAQGWRFEVMEASMNGVGG
                     FKEVVAMVSGQSVYSKLKYESGAHRVQRVPVTESQGRVHTSTATVLVMPEVEEVEYDI
                     DPKDLRVDIYHASGAGGQNVNKVATAVRIVHLPTNIKVEMQEERTQQKNREKAMKIIR
                     ARVADHFAQIAQDEQDAERKSTIGTGDRSERIRTYNFPQNRVTDHRIGLTLQKLDTIL
                     SGKLDEVVDALVLYDQTQKLEELNK"
     gene            complement(9051..9524)
                     /locus_tag="VYO11_001240"
     CDS             complement(9051..9524)
                     /locus_tag="VYO11_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1595810.1"
                     /translation="MTIELRDVTMENYFDVLNLDVKKYQKQFIATNAISLAEAYVYTK
                     NGDFVAPLAVYDNDAIIGFVMIAYDKKIGISSGNYLLFRFMIDKNFQNQGYFKPIMDK
                     VLDYVRTASAGLGNKLWLSYEPENEHARSCYLSYGFKETGEIYENEVVAIYDFNN"
     gene            complement(9514..10113)
                     /locus_tag="VYO11_001241"
     CDS             complement(9514..10113)
                     /locus_tag="VYO11_001241"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HEV1595811.1"
                     /translation="MAQLYYRYGTMNSGKTIEILKVAYNYEEQGKGVVIMTSALDTRD
                     GVGYVSSRIGMKRPALAIEETTDIFGFIRDLPETPYCVLVDEAQFLKRHHVYDLARVV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLLADKIDEIKTICQYCKKKATMVLRTQDGL
                     PVYDGEQIQIGGNETYISVCRKHYFAPMITSNKEQNYDN"
     gene            10237..10419
                     /locus_tag="VYO11_001242"
     CDS             10237..10419
                     /locus_tag="VYO11_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005589823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HEV1595812.1"
                     /translation="MPFVRIDLFEGRTLEQKKALAKEVTEAVVRNTGAPQSAVHVIIN
                     DMPEGTYFPQGEMRTK"
     gene            10557..11930
                     /gene="mnmE"
                     /locus_tag="VYO11_001243"
     CDS             10557..11930
                     /gene="mnmE"
                     /locus_tag="VYO11_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002906470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HEV1595813.1"
                     /translation="MITREFDTIVAISTPLGEGAIGIVRLSGTDSFAIAQKIFKGKDL
                     NKVASHTLNYGHIVDPLTGKVMDEVMVGAMKSPKTFTREDIIEINTHGGIAVTNEILQ
                     LAIREGARLAEPGEFTKRAFLNGRVDLTQAEAVMDIIRAKTDKAMNIAVKQLDGSLSD
                     LINNTRQEILNTLAQVEVNIDYPEYDDVEEATTAVVREKTMEFEQLLTNLLRTARRGK
                     ILREGISTAIIGRPNVGKSSLLNNLLREDKAIVTDIAGTTRDVIEEYVNINGVPLKLI
                     DTAGIRETDDIVEQIGVERSKKALKEADLVLLVLNASEPLTAQDRQLLEISQDTNRII
                     LLNKTDLPEAIETSELPEDVIRISVLKNQNIDKIEERINNLFFENAGLVEQDATYLSN
                     ARHISLIEKAVESLQAVNEGLELGMPVDLLQVDLTRTWEILGEITGDAAPDELITQLF
                     SQFCLGK"
     gene            complement(11977..12912)
                     /gene="dapA"
                     /locus_tag="VYO11_001244"
     CDS             complement(11977..12912)
                     /gene="dapA"
                     /locus_tag="VYO11_001244"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HEV1595814.1"
                     /translation="MSYQDLKKCKIITAFITPFHEDGSINFDAIPALIEHLLAHHTDG
                     ILLAGTTAESPTLTHDEELELFAAVQKVVNGRVPLIAGVGTNDTRDSIEFVKEVAEFG
                     GFAAGLAIVPYYNKPSQEGMYQHFKAIADASDLPIIIYNIPGRVVVELTPETMLRLAD
                     HPNIIGVKECTSLANMAYLIEHKPEEFLVYTGEDGDAFHAMNLGADGVISVASHTNGD
                     EMHEMFIAIAESDMKKAAAIQRKFIPKVNALFSYPSPAPVKAVLNYMGFEAGPTRLPL
                     VPAPEEDAKRIIKVVVDGDYEATKATVTGVLRPDY"
     gene            complement(12968..14044)
                     /locus_tag="VYO11_001245"
     CDS             complement(12968..14044)
                     /locus_tag="VYO11_001245"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000542485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HEV1595815.1"
                     /translation="MGYTVAVVGATGAVGAQMIKMLEESTLPIDKIRYLASARSAGKS
                     LKFKDQDITIEETTETAFEGVDIALFSAGGSTSAKYAPYAVKAGVVVVDNTSYFRQNP
                     DVPLVVPEVNAHALDAHNGIIACPNCSTIQMMVALEPVRQKWGLDRIIVSTYQAVSGA
                     GMGAILETQRELREVLNDGVKPRDLHAEILPSGGDKKHYPIAFNALPQIDVFTDNDYT
                     YEEMKMTKETKKIMEDDSIAVSATCVRIPVLSAHSESVYIETKEVAPIEEVKAAIASF
                     PGAVLEDDVVHQIYPQAINAVGSRDTFVGRIRKDLDAEKGIHMWVVSDNLLKGAAWNS
                     VQIAETLHERGLVRPTAELKFELK"
     gene            complement(14630..14702)
                     /locus_tag="VYO11_001246"
     tRNA            complement(14630..14702)
                     /locus_tag="VYO11_001246"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(14667..14669),aa:Thr,seq:ggt)
     gene            complement(14802..15311)
                     /locus_tag="VYO11_001247"
     CDS             complement(14802..15311)
                     /locus_tag="VYO11_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HEV1595816.1"
                     /translation="MKKLTIRDVADIAIVAAIYVVLTVTPPLNAISYGAYQFRISEMM
                     NFMAFYNPKYIIGVTIGCMIANFFSFGLLDVFVGGGSTLVFLSLGVWLFAKYSKDYLF
                     NGLIRKDHFFFSILFSISMFTIAAELNIVAELPFFLTWFTTGIGEFASLIIGAIIIGK
                     IGRRIDLSK"
     regulatory      complement(15309..15405)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01054"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class II; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF01054"
     gene            15434..15865
                     /locus_tag="VYO11_001248"
     CDS             15434..15865
                     /locus_tag="VYO11_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HEV1595817.1"
                     /translation="MKKPIQKFFNNEILAYLFFGLATTLVSILSRLVIYQLSHQELLA
                     TALANIIGILFAFITNDTIVFKQKKKNRLIRLVKFSLARLSTFLLDLFLTFLFVTQFP
                     HIIGQFVTENIDKINAIETIIAQIFIIIINYILSKVYIFRK"
     gene            15947..16324
                     /gene="mscL"
                     /locus_tag="VYO11_001249"
     CDS             15947..16324
                     /gene="mscL"
                     /locus_tag="VYO11_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HEV1595818.1"
                     /translation="MLKNLKSFLLRGNVIDLAVGVVIASAFGAIVTSLVNDIITPLIL
                     NPALKAAKVERIAQLSWHGVGYGNFLSAIINFIFVGTALFFIIKGIEKAQKLTGIKKE
                     KTAEKKPTELEVLQEIKALLEKK"
     gene            complement(16366..17460)
                     /gene="hemH"
                     /locus_tag="VYO11_001250"
     CDS             complement(16366..17460)
                     /gene="hemH"
                     /locus_tag="VYO11_001250"
                     /EC_number="4.98.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrochelatase"
                     /protein_id="HEV1595819.1"
                     /translation="MKKAILMMTFGSPEEITFEGVADFFTNIRRGVRPQDHEIQTLYD
                     NYVRIGGTPLQKITRQEVALVEARLGNEYSVYFANKFSSPFIPDVIGQMEADGIEQCI
                     CLILEPHYSFYSVMGYEKFLESKQIQFLVIKDWYQEEALLNYWADEIAKILKEEVKQD
                     SFKVIFSAHSVPIFALDFGDPYIDQIFENSKLVAEKLGLSSEQYTNTWQSESDIGIPW
                     IKPDVLEYLREQTEHPDHYIFVPISFISEHIEVLFDNDVECYDLCQEFGVNYHRPPMP
                     NTDSRLIDALVNTIRVNENQEFKEFLPEEETFDELVPSDETKNILAESEDLQMPEFVK
                     KLIEKKGRENVKMPYLIKKMLEKAGKLPKE"
     gene            17615..18838
                     /gene="pepT"
                     /locus_tag="VYO11_001251"
     CDS             17615..18838
                     /gene="pepT"
                     /locus_tag="VYO11_001251"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000222045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HEV1595820.1"
                     /translation="MTYPNLLDRFLTYVKVNTRSDEHSTTTPSTQSQVDFATNVLIPE
                     MKRVGLQNVYYLPNGFAIGTLPANDPSLTRKIGFISHMDTADFNAEGVNPQVIENYDG
                     GVIELGNSGFKLDPADFKSLEKYPGQTLITTDGTSLLGADDKSGIAEIMTAIEYLTAH
                     PEIKHCEIRVGFGPDEEIGVGANKFDAEDFDVDFAYTVDGGPLGELQYETFSAAGAEL
                     HFQGRNVHPGTAKGQMVNALQLAIDFHNQLPENDRPELTEGYQGFYHLIDVTGSVEEA
                     RASYIIRDFEKDAFEARKASMQSIADKMNEELGSNRVTLNLTDQYYNMKEVIEKDMTP
                     ITIAKAVMEDLGITPIIEPIRGGTDGSKISFMGIPTPNIFAGGENMHGRFEYVSLQTM
                     ERAVDTIIGIVAYKG"
     gene            complement(18874..19503)
                     /locus_tag="VYO11_001252"
     CDS             complement(18874..19503)
                     /locus_tag="VYO11_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1595821.1"
                     /translation="MSKANQLLEQIHEEGIRQSLAEEVENLKAATNKADADLDEVNSQ
                     VKDVLTRIASALQQEKENAEQDPQTLVLYQKLYDILMSLHSYLESNNGSDADFDKVDA
                     LLDQLSAKSKDKTALLEPTKAILVLNHQIQSKASASEETSPARNAEANGDNTSAENQP
                     NATAESNIETASDENKPSNTRDSKPAESTSENETTESSTTTGNQEKPVE"
     gene            19468..19689
                     /locus_tag="VYO11_001253"
     CDS             19468..19689
                     /locus_tag="VYO11_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1595822.1"
                     /translation="MDLFQELICLAQKTFYFFLAICRRLLVAIYHVLLKQESYNPRLQ
                     GLTEIRNPDKTMFVQDAIRFAQQHGFNML"
     gene            complement(19960..20971)
                     /locus_tag="VYO11_001254"
                     /pseudo
     CDS             complement(19960..20971)
                     /locus_tag="VYO11_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669441.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
     gene            complement(21197..24316)
                     /gene="phtE"
                     /locus_tag="VYO11_001255"
     CDS             complement(21197..24316)
                     /gene="phtE"
                     /locus_tag="VYO11_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtE"
                     /protein_id="HEV1595823.1"
                     /translation="MKFSKKYIAAGSAVIVSLSLCAYALNQHRSQENKDNNRVSYVDG
                     SQSSQKSENLTPDQVSQKEGIQAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDALFSE
                     ELLMKDPNYQLKDADIVNEVKGGYIIKVDGKYYVYLKDAAHADNVRTKDEINRQKQEH
                     VKDNEKVNSNVAVARSQGRYTTNDGYVFNPADIIEDTGNAYIVPHGGHYHYIPKSDLS
                     ASELAAAKAHLAGKNMQPSQLSYSSTASDNNTQSVAKGSTSKPANKSENLQSLLKELY
                     DSPSAQRYSESDGLVFDPAKIISRTPNGVAIPHGDHYHFIPYSKLSALEEKIARMVPI
                     SGTGSTVSTNAKPNEVVSSLGSLSSNPSSLTTSKKLSSASDGYIFNPKDIVEETATAY
                     IVRHGDHFHYIPKSNQIGQPTLPNNSLATPSPSLPINPGTSHEKHEEDGYGFDANRII
                     AEDESGFVMSHGDHNHYFFKKDLTEEQIKAAQKHLEEVKTSHNGLDSLSSHEQDYPGN
                     AKEMKDLDKKIEEKIAGIMKQYGVKRESIVVNKEKNAIIYPHGDHHHADPIDEHKPVG
                     IGHSHSNYELFKPEEGVAKKEGNKVYTGEELTNVVNLLKNSTFNNQNFTLANGQKRVS
                     FSFPPELEKKLGINMLVKLITPDGKVLEKVSGKVFGEGVGNIANFELDQPYLPGQTFK
                     YTIASKDYPEVSYDGTFTVPTSLAYKMASQTIFYPFHAGDTYLRVNPQFAVPKGTDAL
                     VRVFDEFHGNAYLENNYKVGEIKLPIPKLNQGTTRTAGNKIPVTFMANAYLDNQSTYI
                     VEVPILEKENQTDKPSILPQFKRNKAQENSKLDEKVEEPKTSEKVEKEKLPETGNSTS
                     DSTLEEVPTVDPVQEKVAKFAESYGMKLENVLFNMDGTIELYLPSGEVIKKNMADFTG
                     EAPQGNGENKPSETGKVSTGTVENQPTENKPADSLPEAPNEKPVKPENSTDNGMLNPE
                     GNVGSDPMLDPALEEAPAVDPVQEKLEKFTASYGLGLDSVIFNMDGTIELRLPSGEVI
                     KKNLSDLIA"
     gene            complement(24527..>25562)
                     /gene="phtD"
                     /locus_tag="VYO11_001256"
     CDS             complement(24527..>25562)
                     /gene="phtD"
                     /locus_tag="VYO11_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtD"
                     /protein_id="HEV1595824.1"
                     /translation="IRHPERLGKPNSQITYTDDEIQVAKLAGKYTTEDGYIFDPRDIT
                     SDEGDAYVTPHMTHSHWIKKDSLSEAERAAAQAYAKEKGLTPPSTDHQDAGNTEAKGA
                     EAIYNRVKAAKKVPLDRMPYNLQYTVEVKNGSLIIPHYDHYHNIKFEWFDEGLYEAPK
                     GYTLEDLLATVKYYVEHPNERPHSDNGFGNASDHVQRNKNGQADTNQTEKPQTEKPEE
                     DKEHDEVSEPTHPESDEKENHAGLNPSADNLYKPSTDTEETEEEAEDTTDEAEIPQVE
                     HSVINAKIAEAEALLEKVTDSSIRQNAMETLTGLKSSLLLGTKDNNTISAEVDSLLAL
                     LKESQPAPIQ"
BASE COUNT         7298 a         5309 c         4677 g         8278 t
ORIGIN      
        1 attaaaatgg atactataaa cagcacacca actatttatt ttttgagttt taaactttgg
       61 tagaagtctt gaactcctta tatttacata actatttgcc tctataacta ttatgacacg
      121 aaaccaacaa gcaagttcaa gcacctcctt atctttattc aaatgaggac taagatattc
      181 acaaacttta tcataaacct ctttatcttt tttcataaaa ggggcataca acttagcaaa
      241 tttatcctaa aattttttgt tgcctttatc aatcatttca acactccttt aaatataaaa
      301 atgatcctat caatctttat attgagccta ttttctaatt gataccttgc aagaaaggaa
      361 taatagctgt tcctatacca agtaggaatg taataaatgc agaaagtcat atactgtcat
      421 tcttttctat taaatcattt tgaagtgtct caaagcatcc atgatggctt cttctttttc
      481 aggtgtacac tgtggaataa tttgtttatc ctttttagac ttgttgtaat gttctcgtaa
      541 ttctattcca catttctttt ttatctgtgc aatatataat gtcgaaactt ttaattcaaa
      601 tttattccaa acatattctt tgatttgagc atatgttgct ttgctctccg cacttgtcaa
      661 attcatctca tccagctcaa tttcaacact tatgtgctta tcgacatcga gtttggacaa
      721 aagtgctacc gtctcgacgt gatgcgtttg aggaaataga tccaccggct ggactttctt
      781 caattcatat cccaattctt ggtagagttt gatatcacgc gccatggttg ctacattgca
      841 ggagatatag gcgatgcgat cggctcctgt ttgggcgctt gctttgataa agctttctgt
      901 caagcccttg cgtggaggat caaccaagat aacggttggt tgaatcccat ctttaagcca
      961 attcttcata gcattttcag ctgtgtcaca gacatagtgg gcgtttgaaa tattgttcag
     1021 ctgagcattt tttttactat tctcaaccgc ttctggaatc agttcaacac cgtagacttc
     1081 tttgacatgc ttggcgactg ataaaccaat agttccaata ccagaatagg catcaataat
     1141 cacatcatct ttttttaact ctgcaaagtc aatggctgtt tgatagagtt tctccgccat
     1201 ttcagtattg acttggtaaa aggctgggcc agcgatttgg aagtcatttc ccaacatctg
     1261 gtccgtaata tagtcttgac cataaagagt gcgccactcc ttaccaaaaa tcgcattggt
     1321 attctggtcg ttgatatttt gcatgacaga cacaatctct gggaactgct tgataacttg
     1381 ttcaatcaat tggtcaacac gaaaaacttt tggacgagtt gtcaccaaaa cgaccatgat
     1441 ttgttctgaa tagtgaccac gacgcaccac aagattccga atcaatccag actgttcctt
     1501 ttcgtcataa ggttttaaat caaaacgacg gagcaggtct cgaagagcta ctacgacttg
     1561 gtcaatgaca ggatcctgga taaagaaatc ttcaaggggc atgaggttgt gcgaattctt
     1621 acggaaaaat cctgtttcca agacaccatt cactcgacga acgggcacct gcgccttatt
     1681 gcgatacttg actggatgtt ccataccaag cgtttcagca acttctacat ctgcaattcc
     1741 agcaatcttg tagagactgt tcttgacttg cttggtttta aacttgagct gttctggata
     1801 agaaaggtgt cctaaatccg cgattcctga acgcaggtaa gccaaatcta gatcttgatt
     1861 acggtgtggt gactggacaa ggtatttttc aacttttcca aagccaatct ttttattgac
     1921 cttgaggaca cgcatgagaa ttttttcact cggtaaagca ttctctacaa aaaagaccaa
     1981 accatctacc ttggcaactc ctgccccttc atgggtcaaa tcaacaattt caacttctac
     2041 aatatcattt ttctttaaca ttcttttctc tttctattgg ccgacaaaaa agacggcaac
     2101 gttacggtta ccatccatta taccatgaaa tttcttaaga accaaaactc ttgaagaagt
     2161 tgacaagggc ttgccagagg gagcttaaga agttaccacc gtcctctagc gccttatccg
     2221 catcaaagtt aaggttgata tttttaaaac tgtcgccagc ttgtgatacg atgctttgtt
     2281 taaggtcatt tagggtttta gtgaaatctg cattgctgag gatatcactc tttgagagat
     2341 tcaaggcaaa attgatgatg atattgatct ggtttcctgt tatgacctga tcaagtttgt
     2401 aattttttaa ggtatcttca acaatcttgc ggatatcttc ttctgtcaga tttcccttgc
     2461 tttctttagc tttggcgagt cctgacttga tatcagctag ggcaacgttt aatttattag
     2521 catcatagcc tgatttgtcc ttgttttcag cattgatatc tgacaaagct tttagctctt
     2581 cttgagccaa atctttattg gcttgcggca ccttggctcc attagcttct agcgaatagt
     2641 agatcccagc caaagcactc tcacctgtaa ctggaatggg tgctgctaca gtgattttgg
     2701 cgtgttccac acccaaagtt acggctgcat ttcggtacat atcctgagtt accttagtga
     2761 tgttttcagg tgtttcaatc ttgacctcaa gtggcgattt gtcacctagc ttttgaatct
     2821 tggctgatga atacaactgt aagctagagt cattggccac attcatgatt ttagaataaa
     2881 catcaggtgt catggtcttg agttctttgg tatctgttga ggcattgtag cccagttttt
     2941 taagagtttg atttttttgg tcttcagata gggaggaacc taggacatat tcaggttgga
     3001 cataggtttc atcgataact ttttgaacat ctgttgctgc atggacgcta ttcatagctg
     3061 ttactgccca caagaccgca gcactagtca gaaagagttt ctttctcata gggaatttcc
     3121 tcctttactt ctttagagta atatatctat cttaaagaaa acttataaca aaaacacctg
     3181 gtctagccag atgttgaaaa gagagtgaaa catttgatga tgtaaaggtt aagtcgtacc
     3241 tgtctagaat aataatagtt tcctccattt acatagagtt cagcaccgtg aaaaatggaa
     3301 atgggatgaa tataactata agtctttcca gtcgtattac caagcaaggg ggcaacagtc
     3361 tcacgagagt actgtttggc tagagccaag gtattttcct tgccattttg ggcgataaaa
     3421 tcgatatagg caggtccaaa attataggct tgaacagctg tccagatatc tacacccttc
     3481 ttctgcgcca gatagagatt gcctgtcaga gtttgaatgc cttgccgaat gctagaggca
     3541 ttatcattga tggtgttggt ggaaccactt gcagactcac tagactgcat aacatcgcct
     3601 tcttttcctt ttgtttcagt ataaatcata gcaagcacaa gctcttcgtt tgctggggtg
     3661 tcttgttcac tcaagatttc tcgcaccatg ggttgatagg tcatgacttg tttgacatct
     3721 tgatgaacgc ggtaagcttt atagccagca aaaaggaaga ctgctagtac aagcactctt
     3781 cgaattcgtt taaacattat ttactttgga tatcctcgat atttttgatt aagatagagt
     3841 aggttccatt ttcgttttgg ataaactcaa cagactcggc gtcttgatag acgttattgg
     3901 gaacgatgag ctcaattcca tttgataagg agagtttttg gttttcaaat ttctttaatt
     3961 ggcgactgac atcaatttca tcaaattgaa caggttctgg tacggcttct ttgacttggt
     4021 caataaagct caaacgagcc gtcagattgt tgtcaaaaag gtcattagcc aatttctcag
     4081 gtgacaattc attgctttct tctaggttgt tgaaaatagc tgatttgacc ttggattgaa
     4141 attgaaaatc atctgtgtta aaagattcag caattctctg ggctgttttt tccagttcct
     4201 tgatagattt tttaggagaa atcttaggag cgacagcaag aagattatct gaaaaatagt
     4261 tcaaaaaagt cccgttgtac ttgattcgtt tttcaatcag gtgatacttg ctactctgaa
     4321 gattgaccac caaggcctca tcagctcctg ttccaaatcc aggcaggtta ttctgagtta
     4381 gcttgattgg attatcaact tctcctccga ggtgggtcaa ggtctcccgc agggcaattc
     4441 gcaagaaagc gaaatgttct acaccttctt tagaaaattg aacaaaaatc aagtcattgg
     4501 tcttgagatt ttcagaaatg ctaaactcct ctttccagag attagccagc gttactgatg
     4561 tctccaacaa atcgtctgta atatgattga agaagggatt ttcttcttcg aaaatcccag
     4621 tcttggcttc atctgaatac acatgttcaa tttttttacg taggtattct tcgatttttg
     4681 gagtaatatt gagaaactta tctgctaaga acagctcggt atcatccgga ctgaactggt
     4741 gaataatggc tttcttaata taaatgtcca taaaagtttt attcctcgta taatgggaag
     4801 gcatctgtca attctttgac tgcacttctc acttcttcta atacagcctc attttctgaa
     4861 ttcttaaggg ttttaatgat gagttcagcc actttgcgac tttcttcttc accaaatcca
     4921 cgtgcagtaa tagctgctgc tccgatacga atcccacttg tcttgaatgg tgacaaggtt
     4981 tcgtaaggga ttgaattttt atttagggta atattgactt catccagcaa gttttgagca
     5041 acttttccgt tttctacaac cttagtcaca tcaacaagga agagatggtt ttcagttcca
     5101 cctgaaataa tacggaaatc agggtcttgc aagaagacat ctgccatagc cttgctgttc
     5161 ttaattacat tggcagcata ttccttgaag gctggatcca aaacttcttt gaaggaaact
     5221 gccttagccg ccacaacatg ctctaaagga ccgccctgaa tacctgggaa aatagctgaa
     5281 ttaatttttt tagcaagttc ttcgtcattg gtcaaaatca aaccaccacg aggtccacga
     5341 agggttttgt gggtcgttgt tgttgtgata tgagcgtatg gaactgggct tggatgaagg
     5401 ccagccgcaa ccaaaccagc gatatgggcc atgtccacca tgagcttcgc accgacagca
     5461 tctgcgattt cacggaattt tgaaaaatcg ataatttgag aatatgctga agcaccagct
     5521 acaatcagtt ttggttttac ttcttgggct tgtttcaaga tagcatcaaa gtctaagagt
     5581 tccgtttcag gatcaacact ataagaaaca aagttgtagg tttgaccagg gaagctaaca
     5641 ggagccccat gagtcaaatg accacctgat gccaaatcca ttcccataac cgtatcacct
     5701 ggctcaatca aggatatgta agccgcacag ttggcctgac ttcctgaatg tggttggaca
     5761 ttggcaaatt tagcaccgaa aatttctttt gcgcgttcaa tagcaagagt ctctacaacg
     5821 tctactacat cagttccacc ataataacgg cgtcctgggt aaccctcggc atatttattt
     5881 gtcaagatag acccttgagc tgccataaca gccttggaaa ctacgttttc cgaagcaatt
     5941 aactcgatat tattttgttg gcgttcttct tctttggcaa tagcattcca gagatcagca
     6001 tcatatgctt taaaatcatc tttgtcaaaa atcataggtc ttctccttta ttgtgtgact
     6061 agtccattag tttgatttta caataagaaa atcaaactaa aagatgcgaa taaaccgttt
     6121 ctgcatttta tcacaagtat agccaacttt ttcataaaat gcatgagcac ccagacgatg
     6181 attggcagaa tttaagcgga taaacccata accacatctt ttggcttctt gttccaaccc
     6241 ttgtagtaaa cttttaccga taccttgacc ttgcgcttga ggtgaaactg ctaaagctaa
     6301 gatattaaat cctgctttgg aatagagtga ttcgtaaact tcagcgtgga catatccaag
     6361 taagacatga ttagctgcat cctcatagcc aagtaggaaa tgatgggaat cctgagacag
     6421 tctagctagt tggctagccg tttcctctgg actaaaagta taacccaaag cctcttggtt
     6481 gatgtcacat atcgctttca catctgtttc ttgcaaatct cttagcattt caagcctcct
     6541 caaaagaaat ctctggcaac cgagcaagaa tatcttctcg tttaattgcg ccttggcgta
     6601 agattttcac cttgtctcca gacaaatcca caatagttga atcctgtcca gttagaaaag
     6661 catcgtcttc cagacccaga acctcttggt caaaatcctt tagaatttga tcaaaggtta
     6721 caccacttgc ctgacctgag atattggcag acggcccaat caagggacct gtctctcgaa
     6781 ttaaatccag tgtgataggg tgactgggca tccgaaatcc aatagttgca aggtcagaat
     6841 ttacccaata gggaactcgg tcattggctt cgagaataat ggtcaaggga cctggcaaaa
     6901 aggtctctac aagtttttgt agataagctg gctgattctt agaaaagtgc aagatatcct
     6961 ctaaagaggc aacattgaga ttgagcgcct tgtctctagg acgacgtttg agctggtaaa
     7021 catggtcaac tgctttttcg tctaaggcct tggcaaaaag accataaacc gtctctgtag
     7081 gcagaatgac agctccacca ttttccaact cttgtctaat cctgtccatc atcaaccacg
     7141 accatcctat cttgaccaaa ttggtccttg aatgttcgaa cttttttttc aggaagatgt
     7201 tttctaaaaa gttcgggaac actttgacct tgcttgtatc caatttcaag gtaaatctta
     7261 ccaccatctt tgagatagtc ttttgcatct tccgcaattc tacggtaaat agctaggcca
     7321 tcctcgtctg caaagagagc tagatgaggc tccgaataca agacattcaa gcctacctct
     7381 gactcatctt cacgagagat atagggtgga ttggaaacaa ttatatcata tttttcagaa
     7441 atttctgtaa aacagtcaga ttttttaaaa aatatttgaa gattttgatt tttagcattt
     7501 tcgctagcta aatctaaagc ctcttgagaa acatctgctg ctgtcactga ccaatctggt
     7561 ctattttttg ctagagcgag agcaatagct ccactacctg ttccaatatc cagaactgaa
     7621 agattcgtct caagattttc agttagaata agctccacta actcctctgt ttctggacga
     7681 ggaatcaaaa cccgttcatc cacctttaaa tgcattccat aaaaatctgc ctgtccaatg
     7741 atgtactgag ctggcttgtg agctgctagt tgctggtaaa tatcttctac aaattgtttt
     7801 tcttcctctg ttgtcacctc ctgctggagg gcaaaaataa agtctgtaaa agatagattt
     7861 ttcagactac gatagacaaa agagaggctt tccgcttcct ctccttgtct tatcaactct
     7921 tcttcaaaat ttgaaaataa ttgagctaat ttcattattt gtttaattct tctagttttt
     7981 gtgtttggtc ataaagcacc aaggcatcca caacttcgtc caatttacca gacaaaatcg
     8041 tatctagttt ttggagggtc aagccgatac ggtggtctgt gacacggttt tgtgggaagt
     8101 tataagttcg gatccgttct gaacggtcac cagtaccgat tgtcgactta cgctcagcgt
     8161 cttgttcatc ctgagcaatc tgagcaaagt ggtcagcgac gcgtgcacgg ataatcttca
     8221 tagccttctc gcggttcttc tgctgggtac gttcttcctg catctcaacc ttgatattgg
     8281 ttggcaagtg aacgatacga acggcagtcg caaccttatt gacgttctgt ccaccagcac
     8341 cagaggcgtg atagatgtcg acacgaaggt cttttggatc aatgtcgtat tcaacctctt
     8401 caacttctgg cataacaaga actgtcgctg tcgaagtatg aacacggcct tggctttctg
     8461 tcacaggaac acgttgcaca cggtgggcac ctgattcata cttaagctta gagtatacag
     8521 actgacctga aaccatagca accacttctt taaaaccacc gacaccattc atagaggctt
     8581 ccatgacttc aaagcgccaa ccttgggctt ccgcatactt ttggtacata gttagcaaat
     8641 ctccagcgaa aagtgccgct tcgtctccac cagctgctcc acggatttca aggatgatat
     8701 tcttgtcatc gtttggatcc tttggaagga gcaagatttt tagtttttct tcgtattctt
     8761 ctttttcagc cttggcatct ttgagctctt gcttggccat ttcttccaag tccgcatctc
     8821 cgcctgattc cttaatcatc tcttcagcat cgacgatatt ttgaaggact tgtttgtact
     8881 cacggtaggc tgtaaccgtg tcacgagttg aagcctcttc ttttgaaagc tccataaaac
     8941 gcttggtgtc tgaaacgaca tccgggtcac tgagcaattc tcctaattct tcataacggt
     9001 cttctacagc ttgtagttga tcataaatgt tcattttttc tccttatttc tcaattgtta
     9061 aaatcgtata tcgctactac ttcgttctcg tatatttccc cagtttcttt aaatccataa
     9121 ctgaggtaac aagatcttgc atgttcattt tctggttcat aagacaacca aagtttattg
     9181 cctaaacctg ctgacgctgt ccgaacatag tctagtactt tatccataat tggtttaaaa
     9241 tatccttgat tttgaaaatt cttatcaatc ataaaacgaa atagtaaata atttccacta
     9301 cttattccga tctttttatc ataagctatc atcacaaaac ctataattgc atcattatca
     9361 taaactgcca atggagctac aaaatctcca tttttagtgt agacatatgc ttcagctaaa
     9421 ctaattgcgt tggttgcaat gaattgtttt tgatatttct tgacatccaa attcaaaaca
     9481 tcaaaataat tttccattgt aacatctctt agttcaattg tcatagtttt gctccttgtt
     9541 agaggttatc attggcgcaa aataatgttt acggcaaacc gagatatagg tttcattacc
     9601 gccaatctgg atctgttctc catcgtaaac gggcagtcca tcctgtgttc gcaaaaccat
     9661 agttgccttt ttcttacaat actgacaaat ggtcttgatt tcatcaatct tatctgctaa
     9721 aagcaagaga tacttggaac cttcgaacag ttcattgcga aaatcatttt tcaaaccaaa
     9781 agccatgacg ggtatatcta actcgtccac aacacgagct agatcgtaaa catgatgacg
     9841 tttgagaaac tgggcttcat cgaccaacac acagtaaggt gtttctggta aatcacggat
     9901 aaatccaaag atatccgtcg tctcctcaat cgcaagagca gggcgtttca taccgattcg
     9961 actcgacaca tagccaacac cgtcacgcgt atccagagcc gaggtcataa tcacaacacc
    10021 ttttccttgc tcctcatagt tataggccac cttgagaatc tcaatcgtct tacctgagtt
    10081 catggtccca taacgataat acaactgtgc catgtttctt gcttcacgtc cgtttctaaa
    10141 tttttgctac attctagtat atcataattt tctgaagctt taaacggcaa aatgtggtaa
    10201 aatagaagaa atcaaaaact agtggaggaa gctattatgc catttgtacg catcgattta
    10261 tttgaaggac gcacgctcga gcaaaagaag gctcttgcta aggaagtaac ggaagctgtt
    10321 gtccgtaaca ctggagcccc tcaatctgct gtccatgtca tcatcaacga catgccagaa
    10381 ggaacttact tccctcaagg tgaaatgcgc accaaataag ctagcttaag cagaattgct
    10441 taggcttttt caatctccaa gtagcattca ttgaagaaat agttcaaatt tgttacaatt
    10501 tgaaaagaga cttggagaat tttccaagaa aagagctatt gattaaagga aatattatga
    10561 ttacacgtga atttgatacc atcgttgcta tctctactcc actaggtgaa ggggctattg
    10621 gtattgtccg cctgagcgga acagacagtt ttgctattgc gcaaaagatt tttaaaggaa
    10681 aagacttgaa caaggttgct agccacactc tcaactacgg tcacatcgtt gatcctctga
    10741 ctggtaaagt catggacgag gtcatggtgg gagccatgaa atctccaaaa accttcactc
    10801 gtgaggatat tatcgagatt aacacccacg gtgggattgc ggtgaccaat gagattctcc
    10861 agctagctat ccgtgaagga gctcggttgg ctgaacctgg tgaatttacc aaacgtgcct
    10921 ttttaaacgg tcgcgtagat ttgacacagg ctgaggcggt catggatatc atccgcgcta
    10981 agacagacaa ggccatgaac attgcggtca aacaacttga tggttccctt tctgatctta
    11041 tcaataatac ccgtcaagaa atccttaaca cacttgccca agttgaagtc aatatcgact
    11101 atcctgaata cgatgatgtt gaggaagcta ctactgccgt tgtccgcgag aagactatgg
    11161 agtttgagca attgctaact aatctcctta ggacagcccg tcgaggtaaa attcttcggg
    11221 aaggaatttc aacagctatc atcggccgcc ccaacgttgg aaaatctagc ctgctcaaca
    11281 acctcttgcg tgaagacaag gccatcgtca cagacattgc tgggacaaca cgtgatgtca
    11341 tcgaagaata cgtcaacatc aacggtgtcc ctctcaaatt gattgacaca gcaggtattc
    11401 gtgaaacgga tgacatcgtt gaacaaatcg gtgtggaacg ttcgaaaaaa gccctcaagg
    11461 aagctgactt ggttcttcta gtactaaatg ccagcgagcc actgacagcc caagaccgac
    11521 aacttcttga gattagccaa gatacaaacc gcattatact tctaaataaa accgacctgc
    11581 cagaagcgat tgagacttcg gaactacctg aagacgttat tcgtatttca gtccttaaaa
    11641 accaaaacat cgataagatt gaagagcgaa tcaacaacct cttctttgaa aatgctggtt
    11701 tggttgagca agacgcaacc tacctgtcca atgcccgtca tatttccttg attgaaaagg
    11761 cagttgaaag cttacaagct gttaatgagg gtctagaact ggggatgcca gttgatttgc
    11821 ttcaagtaga tttgacacgt acttgggaaa tcctcggaga aatcactggg gatgccgctc
    11881 cagatgaact tatcacccaa ctctttagcc aattctgttt aggaaaataa gaaaaatcca
    11941 tgatccttca ttcggtcatg gattttattg tctttattag taatctggtc ttaagacacc
    12001 tgttacagtt gccttggtcg cttcgtagtc gccatctacg acaaccttga taatgcgttt
    12061 agcatcttct tctggtgctg gaacaagagg tagacgagtt ggtccagctt caaatcccat
    12121 gtagttcaaa actgccttaa ctggagcagg acttggataa gagaagagag cattaacctt
    12181 aggaatgaat ttacgttgaa tagctgcggc tttcttcata tcactttctg caatggcaat
    12241 aaacatctcg tgcatttcat ccccatttgt atgagaggca acagaaataa ccccatccgc
    12301 cccaaggttc atggcatgga aagcatctcc atcctcacca gtatagacca agaactcttc
    12361 tggtttgtgc tcaatcaagt aagccatatt agccaagcta gtacattctt tgacaccgat
    12421 aatatttgga tgatcagcca agcgaagcat ggtttctgga gttaattcaa caaccacacg
    12481 ccctggaatg ttatagataa taattggtag gtcagaagca tctgcaatag ccttaaagtg
    12541 ctgatacatc ccttcttgag aaggtttgtt gtagtaagga acaatagcaa gcccagctgc
    12601 gaaaccacca aattccgcta cttctttgac aaactcaata gagtcacgcg tatcattagt
    12661 acctacaccc gcaatcaaag gaacgcgtcc attgacaacc ttttgtacag ccgcaaacaa
    12721 ctccaactcc tcatcgtggg tcaaagttgg actctcagca gtcgttcctg cgagaagaat
    12781 tccatccgta tgatgggcca ataaatgctc aatcaaggct ggaatagcat caaagttaat
    12841 ggaaccatcc tcatggaagg gggtaataaa agctgtaatg attttacatt tttttaaatc
    12901 ttgataagac acgaaaacac ctctctattt caaagaagga gttcatctga actcctaaac
    12961 gatatgacta ttttaattca aatttcaatt cagctgttgg acgaaccaat ccacgttcat
    13021 gaagagtttc agcaatctga actgagttcc aagcagcacc tttgagaagg ttatctgaaa
    13081 caacccacat gtgaattcct ttttctgcat ccaagtcttt acggatacga ccaacaaagg
    13141 tatcacgtga accaactgca ttgatggctt gaggatagat ttgatgaact acatcatctt
    13201 caagaacagc acctgggaag gatgcgatag ctgctttgac ttcttcaatt ggagccactt
    13261 cctttgtttc aatataaact gactcagagt gagctgacaa gactggaata cgcacacatg
    13321 tcgcagatac tgcaatgcta tcatcttcca taattttctt agtttccttg gtcatcttca
    13381 tctcttcgta cgtgtaatca ttatcagtga agacatcaat ttgtggaaga gcgttaaagg
    13441 cgataggata atgtttcttg tcaccacctg aaggcaagat ttccgcatgc aaatcacgtg
    13501 gtttcactcc atcattcaag acctcacgaa gttcacgttg tgtctcaaga attgctccca
    13561 taccagcacc tgaaacggct tgataagttg aaacaatgat acggtccaag ccccattttt
    13621 ggcgaaccgg ctcaagagcc accatcattt ggattgttga acagttaggg caggcaatga
    13681 ttccgttgtg ggcatcaagt gcatgagcat tgacctctgg aacaaccaaa ggaacatctg
    13741 gattttgacg gaaataagat gtattatcca ctactaccac gccagctttt actgcgtatg
    13801 gtgcatactt agctgatgtc gaaccacctg ctgaaaagag agcaatatca actccttcaa
    13861 aagctgtttc agtcgtttct tcaatcgtaa tatcttgatc tttaaatttc aatgacttac
    13921 ctgctgaacg tgcagaagca aggtaacgga ttttatcgat tggaagtgtt gattcttcca
    13981 acatttttat catctgagca ccgacagcac ctgtcgcgcc gactacagca actgtatatc
    14041 ccataaataa cctctttcgg aattttctaa aaatttctat aatagaagta ttatactact
    14101 ttttccatga attgcaaagc tttttcatca ttttttggaa aataaaaatc cccaatcgct
    14161 agactaggga ttaagaggca tcttcatgtg atgagcaggt tcacacaact catcaaggtc
    14221 cgctcctgcg ttatgacctc cttatgctca atagtagccc gaagactacc tatcgactca
    14281 tcgcatctac tattctacta aagagaatga cttttgtcaa cagacgaaac tctttatact
    14341 cttcgaaaat ctcttcaaac ttcgtcagcg tcgccttgcc gtatgtatgg ttactgactt
    14401 cgtcagtttc atctacaacc tcaaaaacat gttttgagct gacttcgtca gttctatcta
    14461 caacctcaaa gcagtgcttt gagcaacctg cggctagttt cctagtttac tctttgattt
    14521 tcattgagta ttagttttat ttacacaggt gcataagaaa tatattggaa aaattggggg
    14581 cagacataac aaaaaccctt gtaaatcaag ggcttttctg tctatttaat gctaattgcc
    14641 gggattgaac cggcgacctc atccttacca tggatgcgct ctgccaactg agctaaatca
    14701 gcttacttaa gaagtatact atattcaaaa aaacttgtca agtttcctta gaaattttcc
    14761 ataggaaaaa gccaggtaag aactacctag cttatcttct tctatttact taaatcaatt
    14821 cgacgaccaa ttttaccaat aataatcgct ccaataatca atgaagcaaa ttcaccgatt
    14881 cctgttgtaa accaagtaag gaagaatggt aattctgcta caatatttaa ctctgcagcg
    14941 atagtaaaca tggaaattga aaagaggatt gaaaagaaga aatgatcttt tcgaatcaat
    15001 ccgttaaaga ggtaatcctt gctatatttt gcaaaaagcc aaacacctaa actgaggaat
    15061 actaaggttg aaccaccacc aacaaagaca tctagcagtc cgaagctaaa gaaattagca
    15121 atcatacaac cgatggtaac tccgatgatg tacttaggat tgtaaaaagc cataaagttc
    15181 atcatttctg aaatacgaaa ctgataagca ccatagctga tggcatttag gggcggtgtg
    15241 acagtcaaaa cgacgtagat agcagcgacg attgcaatat ctgcaacatc acgaatagtt
    15301 aattttttca tcttttctcc tttggcggtt atccgcgtgt aatatgcttg gtgaaagaag
    15361 ctaagcacca agggttgatt cattcaacct tactagtata gcacaatagc ctgctttatg
    15421 ctatacttaa agcatgaaaa aacctattca aaaatttttt aacaatgaaa tcttagccta
    15481 tctctttttt ggccttgcga caactctagt ttcgattctc tcacgactag tcatttatca
    15541 actaagtcat caggaactcc ttgctacggc cttggcaaat attatcggta tcttatttgc
    15601 ctttatcaca aatgatacga ttgtatttaa gcaaaaaaag aaaaatagac ttatccgttt
    15661 agtgaaattt tctcttgctc gcctttctac ttttctgtta gacttgtttt taacttttct
    15721 ctttgtaacc caatttcctc acatcatagg gcaattcgta actgaaaaca ttgataagat
    15781 aaatgctatt gaaacaataa ttgcacaaat attcattatt atcatcaatt atatcttgag
    15841 caaggtctat atttttagaa aataatgctc catttatgag ccttttaatt gccttctata
    15901 atgatttagg atacaatgaa acacgaaaca ttgaaaggaa aacagtatgt taaaaaatct
    15961 aaaatcgttc ttgcttcgag gaaatgttat tgaccttgct gtcggtgttg tcattgcctc
    16021 tgcttttggt gctatcgtta cttcacttgt aaacgacatt atcactcctc ttattttaaa
    16081 tcccgctttg aaagctgcta aagtcgaacg tatcgctcaa ctttcttggc atggagtcgg
    16141 ctatggtaac tttttaagtg ctattatcaa ttttatcttt gtgggtaccg ccctcttctt
    16201 tattatcaag ggcattgaaa aagcacagaa actgactggc ataaagaaag aaaaaactgc
    16261 cgaaaaaaaa ccaaccgaat tggaagtcct tcaagaaata aaagctctcc ttgagaaaaa
    16321 ataatcgatt aaaaggatct agcgcaaagc taaatccttt tttctttact ctttgggtaa
    16381 cttgcctgct ttttcaagca tttttttgat aagataaggc atcttaacat tctcccgccc
    16441 ttttttctca atcagttttt tcacaaattc tggcatttgt aaatcttcag attcagctaa
    16501 aatgtttttc gtctcgtctg aaggaactaa ctcatcaaag gtctcttctt ctgggagaaa
    16561 ttccttaaac tcttgatttt cattgactct aattgtattg accaaagcat caatcaaacg
    16621 agaatctgta tttggcattg gtggacgatg gtagtttacc ccaaattcct gacataagtc
    16681 ataacattcc acatcattgt caaacaagac ctcaatatgc tcactgatga aactaatagg
    16741 tacaaaaata taatggtctg gatgttctgt ctgttctctg agatactcca aaacatctgg
    16801 tttaatccat ggaataccaa tatcactctc actctgccaa gtgttggtat attgttctga
    16861 actcaagccc agtttttcag cgactagctt gctattttcg aaaatttggt ctatataagg
    16921 atcaccaaag tccaaggcaa aaataggcac actatgggct gaaaagatga ctttaaagct
    16981 gtcttgcttt acttcttctt ttaaaatctt agcaatttca tctgcccaat agtttaagag
    17041 cgcttcttcc tgataccagt ccttaataac caaaaattga atttgtttgc tttctaaaaa
    17101 tttttcatag cccatgacag agtagaaaga ataatggggc tccaaaatca agcaaataca
    17161 ctgttcaatt ccgtctgctt ccatttgacc gatcacatct ggaataaagg gactggaaaa
    17221 cttattagca aagtagacac tgtattcatt ccccagccta gcttctacca aggcaacctc
    17281 ttgacgggta attttttgca gaggcgtgcc tccaattcgt acataattat catagagagt
    17341 ctgaatctcg tggtcttggg gtctcacccc acgacgaata tttgtgaaaa aatcagctac
    17401 accttcaaag gtaatctctt ctggtgaacc gaaggtcatc attaaaattg cttttttcat
    17461 gactgcttcc ttgtgatgtt tttatcaagt ttattttatc attaattcat cgataagtaa
    17521 acgctaacat agggacattc tcaatcttct gtcttttgtt tttctcttct ttctatgata
    17581 caatggaaaa aataaattca aaaggagttt ttttatgact tatccaaatc tcttggaccg
    17641 cttcttaacc tacgttaagg tcaacacgcg ctctgatgaa cactctacta ctactccaag
    17701 tacacagagt caggttgact tcgcaacaaa tgtcctaatt cctgaaatga aacgtgttgg
    17761 actgcaaaat gtttactatc taccgaatgg ttttgctatt ggaaccttgc cagccaacga
    17821 tccgtcttta acacgtaaga ttggttttat atcgcacatg gatactgctg attttaatgc
    17881 tgaaggagtc aatccacagg taattgaaaa ctacgatggt ggtgtgattg aactagggaa
    17941 ttctggtttc aaactcgatc cagctgactt caagagtctt gaaaaatatc caggacaaac
    18001 gctcatcaca acagatggaa caagcttgct aggtgctgat gacaagtcag gaattgctga
    18061 aattatgaca gccattgaat atctaactgc tcatcctgaa attaagcact gtgagattcg
    18121 tgttggtttt ggtccagatg aagaaatcgg tgttggtgcc aataaatttg atgcagaaga
    18181 ttttgatgtg gattttgcct acactgttga tggtggtcca ctaggtgaac ttcagtacga
    18241 gactttctca gccgctggtg ctgaattgca tttccaaggc cgtaatgtcc accctggtac
    18301 tgccaaaggg cagatggtca atgcccttca gctagcaatt gattttcata atcaacttcc
    18361 agaaaatgac cgacctgagt taactgaagg ttaccaaggt ttttaccatc taatagatgt
    18421 gacaggtagt gttgaggagg cgcgtgcaag ctacatcatt cgtgattttg aaaaagatgc
    18481 ctttgaagcg cgtaaagcat ccatgcaatc tatcgctgat aagatgaatg aagaacttgg
    18541 gagcaaccgt gtcactctca acttgacaga ccagtactac aatatgaaag aagtcattga
    18601 aaaagatatg actccaatta ccattgctaa agccgttatg gaagatctag gtatcacgcc
    18661 tattatcgaa ccaatccggg gtggaacaga cggctctaag atttccttta tgggaatccc
    18721 aactccgaat atctttgcag gtggcgaaaa tatgcacgga cgttttgaat acgttagcct
    18781 tcagactatg gaacgtgcag ttgataccat cattggcatc gtagcttata aaggctaaaa
    18841 agacgaggtg gctcagctac ttcgcctttc tttttattct actggttttt cttgatttcc
    18901 agtagttgta gaagattctg ttgtttcatt ttctgaagtt gattcagcag gtttagaatc
    18961 tcttgtattg cttggtttgt tttcgtcgct agcagtttca atgttagatt ctgcagttgc
    19021 gtttggttgg ttctcagcac tggtgttatc accatttgct tcagcatttc ttgctggact
    19081 tgtttcttca cttgcgctag cttttgactg gatttgatga ttcaaaacta gaatagcttt
    19141 tgtcggttca agtaaagctg ttttgtcttt actcttagca gaaagttgat ctaataatgc
    19201 atccacctta tcaaagtccg catcagatcc attattactt tctaaataag agtgaagcga
    19261 catgagaata tcgtagagtt tttgatagag tacaagtgtc tgaggatctt gctcagcatt
    19321 ttccttttct tgttgaaggg cgctagcgat acgagtcaaa acatctttta cctgactgtt
    19381 tacttcatcc aagtctgcat cagccttgtt tgtggcagct tttagatttt ctacttcttc
    19441 tgccaaggat tgtctgattc cttcttcatg gatttgttcc aagagttgat ttgccttgct
    19501 caaaagactt tctacttctt ccttgctatc tgtcgcagat tattggttgc catctaccat
    19561 gtactcctaa aacaggagag ttataatcca agattacaag gccttacaga aataagaaat
    19621 ccagataaga caatgttcgt ccaagacgct attcgcttcg cacagcagca cggattcaat
    19681 atgctttaat tttaaagttt aggtgtcaag acctcttttt agtgtgccca aaatttagag
    19741 aagtaatcaa tcaactaact tttatttttt tcaaactttc agtaaactga cctaaagcta
    19801 actcaatctg tctttgtaga tgcttctgct atcagctaga agttgatcta cttttgccaa
    19861 gactgccttc tcatcaaaag ttccaggttg atagttggat tgcagggatg gaatcttgtt
    19921 tttcaaagcc gcttcatatc ccttagtttg aaccttgatg tagtgattgt ggtcgccatg
    19981 aggaatcaca aaaccttctg aatcttcact tataattcga ttggcatcaa aaccatgacc
    20041 atcttcttcc tcatggtgga catgtagtga cggattactt aatacagaac tagaagaact
    20101 tcctacctct tccgtgttag agtgtgatgg gggattgtta agagatgact taggaatata
    20161 gtgatagtga tccccatgtc ttactatata agcatcacct gtatctctga caatatcatt
    20221 agggttaaag acatatgtgg ctgctaattc acctgccgac aagtcactct caggaatgaa
    20281 atgatagtga ccaccatgtg gtactatagt agattgaaat agaatatgag caaattgata
    20341 aggggatttt aaagtaattt ctaacaatga tttagaaact atgatgtgct attctaaatt
    20401 caactcacta tatataacca tcatcggtag tataacgtcc ctgtaatttt gctacagata
    20461 cttctgcact agctccttta tcgtctttac catgttcttg tttttggcga ttgatttcat
    20521 cttttgttcg tacattttct gcatgagctt gatctttaag gtaaacataa tactttccat
    20581 ctaccttaat aatatatcct cccttaacct aactgacgat atcttgatct ttcggctgat
    20641 agttgggggc tttcattaat agctcttcac taaagagcgc atcaaaagga actttaccat
    20701 tatagtagtg ataatgatcg ccatgagaag ttacataacc ttgatctgta atcttaataa
    20761 caatttgttt tgcttgaatt ccttcttttt gactaaccta gtctggagtc aaattttcag
    20821 tcttcttagt gtctttatta ctgtttacat atgaaacacg atttttatct gtattggcct
    20881 gttagctatg ttggttcaga gcataaacac acagacttaa ggaaaggata acaacagatc
    20941 cagctgctat atatttcttt ttaaatttca taattacctc atttctataa ttatttatat
    21001 gatgtcttca ttattaaatg attaaataaa ttaattaacc aattaattaa ctagtaaata
    21061 ttccacctct ttttaagttg tatgtcaaga aattttatat attaataata aaatgaaatt
    21121 ctcccaaagt cagagtttta tttctaactt ttgagagaac ttcatttttg attcagactt
    21181 tttctactgc tattccttac gctatgagat cagataaatt cttttttatc acttctccac
    21241 ttggcaatct taattcaatc gttccatcca tattgaatat aacactatct aagcctaatc
    21301 cgtaactagc tgtaaatttt tctaattttt cttgtacagg atctactgct ggagcttcct
    21361 ctaatgctgg atctaacata gggtcactcc ccacattccc ttctggattc aacattccat
    21421 tatccgttga gttttctggt tttacaggtt tttcgtttgg tgcctctggt aaagaatctg
    21481 ctggtttatt ttctgttggt tggttctcaa ctgttccagt agatactttt ccagtttcag
    21541 atggtttatt ttcaccattt ccttgaggtg cttctcctgt aaaatctgcc atattctttt
    21601 taatgacttc tcccgatggt aaatataatt caattgttcc gtccatatta aacaagacat
    21661 tttctagctt catcccataa ctttcagcaa attttgctac tttttcttgt acaggatcca
    21721 ctgtaggaac ttcttctaac gttgaatcac tagtactgtt cccagtttca ggaagctttt
    21781 ctttttctac cttctcacta gtctttggtt cttctacctt ttcatcaagt tttgagtttt
    21841 cttgtgcttt attcctttta aattgtggta gaatacttgg tttatcagtt tgattttctt
    21901 tttccaagat aggtacttcc acaatataag tcgattgatt gtccaaataa gcatttgcca
    21961 tgaaggttac aggaatttta tttccggccg ttctggttgt tccttggttt aatttcggaa
    22021 tcggtaattt aatttcacca actttatagt tattttctaa ataagcattt ccatgaaatt
    22081 catcaaacac tctgactaaa gcatcagttc ctttaggcac tgcaaattga gggttcactc
    22141 ttaaataagt atcccctgca tggaaaggat agaaaatcgt ttgactggcc attttgtaag
    22201 ctaaagaggt tggaactgta aatgtaccat cataacttac ttctggataa tcttttgaag
    22261 cgatagtata cttaaatgtt tgtcctggta aataaggttg atctaattca aagtttgcaa
    22321 tattccctac tccttctcca aatactttac cagatacttt ctccaatact tttccatctg
    22381 gtgttattaa ttttactagc atattgatac ctaatttttt ttccaattca ggcggaaaac
    22441 taaaagaaac gcgtttttga ccattggcta gagtaaagtt ttgattatta aacgtactat
    22501 tttttaacaa attaacaaca ttcgttaatt cttctccagt ataaacttta ttcccttctt
    22561 ttttagcaac tccttcttcg ggtttaaaca gttcatagtt actgtgagaa tgaccaattc
    22621 caaccggttt atgttcatca atcggatctg catgatggtg atctccatgc ggataaataa
    22681 tcgcattttt ttctttattc acgacaatac tttcacgttt gacaccatat tgtttcataa
    22741 tgccagcaat tttttcttcg atttttttat ctaaatcttt catttctttg gcattacctg
    22801 gataatcctg ttcatgagat gacaaagaat ctaatccatt atgactagtt ttaacttcct
    22861 ctaaatgttt ttgcgcagcc ttaatttgct cttctgtcaa gtccttcttg aagaaataat
    22921 gattgtggtc tccgtgactc atgacaaaac ctgattcatc ttcagcgata atacgattag
    22981 catcaaatcc gtatccatct tcttcatgtt tctcatgtga agttcctgga ttgattggaa
    23041 gagatggaga aggtgttgct agactattgt ttggaagagt cggttgccca atttgatttg
    23101 attttggaat gtaatggaaa tgatcaccat gtcttacaat ataagctgta gccgtttctt
    23161 caacgatatc ttttggatta aaaatataac catcagatgc tgaagagagt ttcttacttg
    23221 tcgttaaaga agaaggattg cttgaaagac tgcctagact agacactact tcattaggtt
    23281 ttgcatttgt agaaactgta gaaccagttc cactgatagg caccattctg gcaatctttt
    23341 cttctaaggc agaaagcttg ctgtaaggaa taaagtggta atggtcgcca tgcggaatcg
    23401 caactccatt tggtgtacga ctgataatct tagcagggtc aaagaccagg ccatctgatt
    23461 cactgtaacg ttgggcgcta ggtgaatcat agagttcctt caaaagactc tggagatttt
    23521 cagatttatt tgctggcttg ctagttgatc cttttgctac agattgcgtg ttattgtcac
    23581 tagctgttga agaatagctt aactgactcg gttgcatatt ttttccagcc agatgtgctt
    23641 tagctgctgc taattcacta gcagataaat cgcttttggg aatgtagtga tagtgacctc
    23701 catgaggaac gatataagca ttacccgtat cttcgataat atcagctgga ttaaagacat
    23761 aaccatcatt tgtcgtatat cgtccctgag accttgctac agcaacatta gagttaacct
    23821 tctcattatc tttgacatgt tcttgttttt gacgattgat ttcatcttta gttcgaacat
    23881 tatcagcatg agctgcatct ttcaggtaga cataatattt tccatcgacc ttgatgatat
    23941 aaccaccctt gacttcattg acaatatcag cgtctttaag ttgatagttt ggatccttca
    24001 tcaagagttc ttcactaaag agggcatcat aaggaacttt cccattatag taatgatagt
    24061 ggtcaccgtg tgacgttaca tagccctgat ctgtaatttt gattacaatt tgctcagcct
    24121 gaattccttc tttctggcta acctggtctg gtgtcaagtt ttcacttttc tgacttgact
    24181 ggctgccatc cacataagag acacgattat tgtccttatt ttcctgcgaa cgatgctggt
    24241 ttagtgcata ggcacataga ctcaaggata cgataacagc tgatccagct gctatatatt
    24301 ttttactaaa tttcataaat ccctcatttc aataaatgat gaagtttttt tctcaacttc
    24361 ttttacttta ttaaatagtt ttctaaaccg attatttaac catttaatta accagtaaat
    24421 agtctactat ttaaaattac ttttgtcaag tttctgttac gtttttctaa aaaagagaag
    24481 taacacgaaa ggttacttct ccataaaata tgctccattc attttactac tgtataggag
    24541 ccggttgact ttcttttaac aaagccaaga gactatctac ttctgctgaa atagtattat
    24601 tatctttcgt tccgagaaga agactacttt ttagaccagt caatgtctcc atagcatttt
    24661 gtctaatact agaatctgtt actttttcta gcaaggcctc cgcctctgct atcttagcgt
    24721 taataacaga atgctctact tgaggaattt cagcctcatc tgtagtatct tcagcttctt
    24781 cctctgtctc ttccgtatca gtgcttggtt tataaagatt atctgctgaa ggatttaaac
    24841 cagcgtgatt ctctttttca tcagattcag ggtgagttgg ctcacttact tcatcatgtt
    24901 ccttatcttc ctcaggtttt tctgtctgag gtttctccgt ttgattggta tcagcttgac
    24961 catttttgtt tctttgaaca tggtcgctag cgttaccaaa accattatct gaatgcggac
    25021 gttcgtttgg atgttcgaca tagtacttga cagtcgccaa aagatcctca agagtatacc
    25081 ccttaggtgc ctcataaagg ccttcgtcaa accactcaaa tttgatgtta tggtaatggt
    25141 cataatgagg tatgattaaa ctaccgtttt tgacttctac agtatattga agattgtaag
    25201 gcatacgatc aagtggcacc ttcttagctg ctttcacgcg gttgtagata gcttctgctc
    25261 cttttgcctc agtatttcct gcatcctgat ggtctgtcga aggaggggtc aaacctttct
    25321 ctttagcata agcctgggct gccgctctct cagcttcaga caaactatct tttttaatcc
    25381 agtggctatg ggtcatatgt ggagttacat aggcatcccc ctcatcactg gttatatcac
    25441 gaggatcaaa gatataaccg tcttctgttg tgtacttgcc tgccaacttg gctacttgaa
    25501 tctcatcatc agtgtaggta atttgcgaat ttggttttcc taaacgttct ggatgacgaa
    25561 tc
//
LOCUS       DAVLXH010000028        24937 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00028199
            SAMN33607166-rid17955573.denovo.028, whole genome shotgun sequence.
ACCESSION   DAVLXH010000028 DAVLXH010000000
VERSION     DAVLXH010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607166
            Sequence Read Archive: SRR23725544
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 24937)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24937)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721421.1
            Genome Coverage       :: 115x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:42:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,210
            CDSs (total)                      :: 2,161
            Genes (coding)                    :: 2,023
            CDSs (with protein)               :: 2,023
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 73 of 138
            Pseudo Genes (incomplete)         :: 60 of 138
            Pseudo Genes (internal stop)      :: 40 of 138
            Pseudo Genes (multiple problems)  :: 31 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24937
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607166-rid17955573.denovo.028"
                     /strain="AUSMDU00028199"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1349"
     gene            200..565
                     /locus_tag="VYO11_001257"
     CDS             200..565
                     /locus_tag="VYO11_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HEV1595825.1"
                     /translation="MYRVIEMYGDFEPWWFLEGWEEDIVASRKFDQYYDALKYYKTCW
                     FRLEQESPLYKSRSDLMTIFWDPEDQRWCDECDEYLQQYHSLALLQDEQVIPDEKLRS
                     GYEKQTSQERNRSCRMKLK"
     gene            641..1582
                     /locus_tag="VYO11_001258"
     CDS             641..1582
                     /locus_tag="VYO11_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000249584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II/IV secretion system protein"
                     /protein_id="HEV1595826.1"
                     /translation="MVQEIAQEIIRSARKKGAQDIYFVPKLDAYELHMRVGDERCKIG
                     SYDFEKFAAVISHFKFVAGMNVGEKRRSQLGSCDYAYDQKMASLRLSTVGDYRGHESL
                     VIRLLHDEEQDLHFWFQDIEELGKQYRQRGLYLFAGPVGSGKTTLMHGLSKSLFKGQQ
                     VMSIEDPVEIKQDDMLQLQLNEAIGLTYENLIKLSLRHRPDLLIIGEIRDSETARAVV
                     RASLTGATVFSTIHAKSIRGVYERLLELGVSEEELAVVLQGVCYQRLIGGGGIVDFAN
                     RDYQEHQAAKWNEQIDQLLKDGHITSLQAETEKISYS"
     gene            1530..2546
                     /locus_tag="VYO11_001259"
     CDS             1530..2546
                     /locus_tag="VYO11_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000355375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HEV1595827.1"
                     /translation="MDISQVFRLRRKKLATAKQKNIITLFNNLFSSGFHLVETISFLD
                     RSALLDKQCVIQMRAGLSQGKSFSEMMESLGCSSTIVTQLSLAEVHGNLHLSLGKIEE
                     YLDNLAKVKKKLIEVATYPLILLGFLLLIMLGLRNYLLPQLDSSNIATQIIGNLPQIF
                     LGMVGLVSVLALLALTFYKRSSKMSVFSILARLPFIGIFVQTYLTAYYAREWGNMISQ
                     GMELTQIFQMMQEQGSQLFKEIGQDLAQTLKNGREFSQTIGTYPFFRKELSLIIEYGE
                     VKSKLGSELEIYAEKTWEAFFTRVNRTMNLVQPLVFIFVALIIVLLYAAMLMPMYQNM
                     EVNF"
     gene            2548..2874
                     /locus_tag="VYO11_001260"
     CDS             2548..2874
                     /locus_tag="VYO11_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HEV1595828.1"
                     /translation="MKKMMTFLKKAKVKAFTLVEMLVVLLIISVLFLLFVPNLTKQKE
                     AVNDKGKAAVVKVVESQAELYSLDKNEDATLSKLQGDGRITEEQVKAYNEYYTKNGGA
                     NRKVND"
     gene            2867..3271
                     /locus_tag="VYO11_001261"
     CDS             2867..3271
                     /locus_tag="VYO11_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HEV1595829.1"
                     /translation="MIKAFTMLESLLVLGLVSILALGLSSSVQSTFAAVEEQIFFMEF
                     EELYRETQKRSVASQQKTSLNLDGQTLSNGSQKLTVPKGIQAPSGQSITFDRAGGNSS
                     LAKVEFQTSKGAIRYQLYLGNGKIKRIKETKN"
     gene            3276..3536
                     /locus_tag="VYO11_001262"
     CDS             3276..3536
                     /locus_tag="VYO11_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000601743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1595830.1"
                     /translation="MILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVA
                     KMALQTGQNQVSINGVEIQVFSSEKGLEVYHGSEQLLAIKEP"
     gene            3499..3960
                     /locus_tag="VYO11_001263"
     CDS             3499..3960
                     /locus_tag="VYO11_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000250539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGF"
                     /protein_id="HEV1595831.1"
                     /translation="MVQNSCWQSKSHKVKAFTLLESLLALIVISGGLLLFQTMSQLLI
                     SEVRYQQQSEQKEWLLFVDQLEAELDRSQFEKVEGNRLYMKQDGKDIAIGKSKSDDFR
                     KTDASGRGYQPMVYGLKSAQITEDNQLVHFRFQFQKGLEREFIYRVEKEES"
     gene            3938..4384
                     /locus_tag="VYO11_001264"
     CDS             3938..4384
                     /locus_tag="VYO11_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001851880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGF"
                     /protein_id="HEV1595832.1"
                     /translation="MWKKKKVKAGVLLYAVTIAAIFSLLLQFYLNRQIAHYQDYALNK
                     EKLVAFAMAKRTKDKAEQESGEQVFNLGQVSYQNKKTSLVTTVRTSKSQYEFLFPSVK
                     IKEEKRDKKEEVATDSSEKAEKKNQKRSLKRKRIPSQFNYNALNPE"
     gene            4487..5081
                     /locus_tag="VYO11_001265"
                     /pseudo
     CDS             4487..5081
                     /locus_tag="VYO11_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679792.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
     gene            5142..6095
                     /locus_tag="VYO11_001266"
     CDS             5142..6095
                     /locus_tag="VYO11_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000345081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEV1595833.1"
                     /translation="MDFEKIEQAYTYLLENVQVIQSDLATNFYDALVEQNSIYLDGET
                     ELNQVKDNNQALKRLALRKEEWLKTYQFLLMKAGQTEPLQANHQFTPDAIALLLVFIV
                     EELFKEEEITILEMGSGMGILGATFLTSLDKKVDYLGMEVDDLLIDLAASMADVIGLQ
                     AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVASRHQVASSQEHTYAHHLLMEQGL
                     KYLKSDGYAIFLAPSNLLTSPQSDLLKEWLKEEASLVAMISLPENLFANAKQSKTIFI
                     LQKKSEIAVEPFVYPLASLQDASVLMKFKENFQKWTQGTEI"
     gene            6146..7336
                     /locus_tag="VYO11_001267"
     CDS             6146..7336
                     /locus_tag="VYO11_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HEV1595834.1"
                     /translation="MTKTIAINAGSSSLKWQLYLMPEEKVLAKGLIERIGLKDSISTV
                     KFDGRSEQQILDIENHAQAVKILLDDLIRFDIIKAYDEITGVGHRVVAGGEYFKESTV
                     VEGDVLEKVEELSLLAPLHNPANAAGVRAFKELLPDITSVVVFDTSFHTSMPEKAYRY
                     PLPTKYYTENKVRKYGAHGTSHQFVAGEAAKLLGRPLEDLKLITCHIGNGGSITAVKA
                     GKSVDTSMGFTPLGGIMMGTRTGDIDPAIIPYLMQYTEDFNTPEDISRVLNRESGLLG
                     VSANSSDMRDIEAAVAEGNHEASLAYEMYVDRIQKYIGQYLAVLNGADAIVFTAGVGE
                     NAENFRRDVISGISWFGCDVDDEKNVFGVTGDISTEAAKIRVLVIPTDEELVIARDVE
                     RLKK"
     gene            7485..7856
                     /gene="rnpA"
                     /locus_tag="VYO11_001268"
     CDS             7485..7856
                     /gene="rnpA"
                     /locus_tag="VYO11_001268"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000739244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HEV1595835.1"
                     /translation="MKKNFRVKREKDFKAIFKEGTSFANRKFVVYQLENQKNHFRVGL
                     SVSKKLGNAVTRNQIKRRIRHIIQNAKGSLVEDVDFVVIARKGVETLGYAEMEKNLLH
                     VLKLSKIYQEGNGSEKETKVD"
     gene            7831..8655
                     /locus_tag="VYO11_001269"
     CDS             7831..8655
                     /locus_tag="VYO11_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HEV1595836.1"
                     /translation="MKKKLKLTSLLGLSLLIMTACATNGVTSDITAESADFWSKLVYF
                     FAEIIRFLSFDISIGVGIILFTILIRTVLLPVFQVQMVASRKMQEAQPRIKALREQYP
                     GRDMESRTKLEQEMRKVFKEMGVRQSDSLWPILIQMPVILALFQALSRVDFLKTGHFL
                     WINLGSVDTTLVLPILAAVFTFLSTWLSNKALSERNGATTAMMYGIPVLIFIFAVYAP
                     GGVALYWTVSNAYQVLQTYFLNNPFKIIAEREAVVQAQKDLENRKRKAKKKAQKTK"
     gene            8674..9660
                     /locus_tag="VYO11_001270"
     CDS             8674..9660
                     /locus_tag="VYO11_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein jag"
                     /protein_id="HEV1595837.1"
                     /translation="MVVFTGSTVEEAIQKGLKELDIPRMKAHIKVISREKKGFLGLFG
                     KKPAQVDIETISETTVVKANQQVVKGVPKKINDLNEPVKTVSEETVDLGHVVDAIKKI
                     EEEGQGISDEVKAEILKHERHASTILEETGHIEILNELQIEEAMREEAGADDLETEQD
                     QAESQELEDLGLKVETNFDIEQVATEVMAYVQTIIDDMDVEATLSNDYNRRSINLQID
                     TNEPGRIIGYHGKVLKALQLLAQNYLYNCYSRTFYITINVNDYVEHRAEVLQTYAQKL
                     AIRVLEEGRSHQTDPMSNSERKIIHRIISRMDGVTSYSEGDEPNRYVVVDTE"
     gene            9711..10334
                     /locus_tag="VYO11_001271"
     CDS             9711..10334
                     /locus_tag="VYO11_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P"
                     /protein_id="HEV1595838.1"
                     /translation="MLNKIRDYLDFSGLQYRSPDKAGAEREKMLAFRHKGQEARKAFT
                     ELAKAFQASHPEWQLQQTSQWMNQAQRLRPHFWVYLQRDGQVTEPMMALRLYGTSTDF
                     GISLEVSFIERKKDEQTLEKQAKILDIPTVKGIYYLAYSDGQSQRWEANEEKRRTLRE
                     KVRSQEVRKVLVKVDVPMTENSSEEEIVEGLLKSYSKILPYYLATRK"
     gene            10465..11922
                     /locus_tag="VYO11_001272"
     CDS             10465..11922
                     /locus_tag="VYO11_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEV1595839.1"
                     /translation="MEVVSSVLNWFSSNILQNPAFFVGLLVLIGYALLKKPAHDVFSG
                     FVKATVGYMLLNVGAGGLVTTFRPILAALNYKFQIGAAVIDPYFGLAAANNKIAAEFP
                     DFVGTATTALLIGFGINILLVALRKITKVRTLFITGHIMVQQAATVSLMVLFLVPQLR
                     NAYGTAAIGIICGLYWAVSSNMTVEATQRLTGGGGFAIGHQQQFAIWFVDKVAGRFGK
                     KEESLDNLKLPKFLSIFHDTVVASATLMLVFFGAILLILGPDIMSNKEVITSGTLFNP
                     AKQDFFMYIIQTAFTFSVYLFVLMQGVRMFVSELTNAFQGISNKLLPGSFPAVDVAAS
                     YGFGSPNAVLSGFTFGLIGQLITIVLLIVFKNPILIITGFVPVFFDNAAIAVYADKRG
                     GWKAAVILSFISGVLQVALGALCVALLDLASYGGYHGNIDFEFPWLGFGYIFKYLGIV
                     GYVLVCLFLLVIPQLQFAKAKDKEKYYNGEVQEEA"
     gene            11945..12226
                     /locus_tag="VYO11_001273"
     CDS             11945..12226
                     /locus_tag="VYO11_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV1595840.1"
                     /translation="MVKVLAACGNGMGSSMVIKMKVENALRKLNQTDFTVNSCSVGEA
                     KGLAVGYDIVIASLHLIQELEGRTNGKLIGLDNLMDDKEITEKLSQALQ"
     gene            12303..12788
                     /locus_tag="VYO11_001274"
     CDS             12303..12788
                     /locus_tag="VYO11_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV1595841.1"
                     /translation="MNLKQALIDNDSIRLGLEANDWKEAVKVAVDPLIESGAILPEYY
                     DAIIESTEEYGPYYILMPGMAMPHARPEAGVQSDAFSLITLQNPVVFSDGKEVSVLLA
                     LAATSSKIHTSVAIPQIIALFELEDSIARLQACQTKEDVLAMIEESKDSPYLEGLDLE
                     S"
     gene            12805..13470
                     /locus_tag="VYO11_001275"
     CDS             12805..13470
                     /locus_tag="VYO11_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HEV1595842.1"
                     /translation="MTKRIPNLQVALDHSDLQGAIKAAVSVGQEVDIIEAGTVCLLQV
                     GSELAEVLRSLFPDKIIVADTKCADAGGTVAKNNAVRGADWMTCICCATIPTMEAALK
                     AIKTERGERGEIQIELYGDWTFEQAQLWLDAGISQAIYHQSRDALLAGETWGEKDLNK
                     VKKLIDMGFRVSVTGGLDVDTLKLFEGVDVFTFIAGRGITEAVDPAGAARAFKDEIKR
                     IWG"
     gene            13474..14337
                     /locus_tag="VYO11_001276"
     CDS             13474..14337
                     /locus_tag="VYO11_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000252119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HEV1595843.1"
                     /translation="MVRPIGIYEKATPTHFTWLERLNFAKELGFDFIEMSIDERDERL
                     ARLDWSKEERLEVVKEIYETGVRIPSICFSGHRRYPLGSKDSVLEEKSLELMKKCIEL
                     AQDLGVRTIQLAGYDVYYEEKSPQTRQRFIKNLRKACDWAEEAQVVLAIEIMDDPFIN
                     SIEKYLAIEKEIDSPFLFVYPDIGNVSAWHNDIYSEFYLGHHAIAALHLKDTYAVTES
                     SKGQFRDVPFGQGCVKWEEAFDILKETNYNGPFLIEMWSENCETVEETRAAIQEAQAF
                     LYPLIKKAGLM"
     gene            14339..15043
                     /locus_tag="VYO11_001277"
     CDS             14339..15043
                     /locus_tag="VYO11_001277"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HEV1595844.1"
                     /translation="MNQVINAMRKRVCDANQSLPKHGLVKFTWGNVSEVNRELGVIVI
                     KPSGVDYDELTPENMVVTDLDGKILEGDLRPSSDLPTHVQLYKAWSEIGSVVHTHSTE
                     AVAWAQAGRDIPFYGTTHADYFYGSIPCARSLTKDEVEVAYEKDTGLVIVEEFEHRGL
                     NPVEVPGIVVRNHGPFTWGKNPENAVYHSVVLEEVSKMNRFTEQINPRVEPAPQYILE
                     KHYQRKHGPNAYYGQK"
     gene            15220..16893
                     /locus_tag="VYO11_001278"
     CDS             15220..16893
                     /locus_tag="VYO11_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HEV1595845.1"
                     /translation="MVLDKASCDLLQYLMDQETSKTIMAISKDLKESRRKIYYHIDKI
                     NAALVDEALHIISIPRIGIHLTEEQRDACCKLLSEVDSYDYIMSAHERMMIMLLWIGI
                     SKERITIEKLIELTEVSRNTVLNDLNSIRYQLTLEQYQVTLQVSKSQGYHLHAHPLNK
                     IQYLQSLLYHIFMEENATFVSILEDKMKERLDDECLLSVEMNQFFKEQVPLVEQDLGK
                     KINHHEITFMLQVLPYLLLSCHNVEQYQERHQDIEKEFSLIRKRIEYQVSKKLGERLF
                     QKFEISLSGLEVSLVAVLLLSYRKDLDIHAESDDFRQLKLALEEFIWYFESQIRMEIE
                     NKDDLLRNLMIHCKALLFRKTYGIFSKNPLTKQIRSKYGELFLVTRKSAEILEGAWFI
                     RLTDDDIAYLTIHIGGFLKYTPSSQKNMKKVYLVCDEGVAVSRLLLKQCKLYFPNEQI
                     DTVFTTEQFKSVEDIAQVDVVITTNDDLDSRFPILRVNPILEAEDILKMLDYLKHNIF
                     RNKSKSFSENLSSLISSYIVDSKLASKFQEEVQTLINKEIVVQAFLEDI"
     gene            17005..18096
                     /gene="ulaG"
                     /locus_tag="VYO11_001279"
     CDS             17005..18096
                     /gene="ulaG"
                     /locus_tag="VYO11_001279"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HEV1595846.1"
                     /translation="MPNVKEITRESWILATFPEWGTWLNEEIEEEVVPEGNFAMWWLG
                     NCGTWIKTPAGANVVMDLWSNRGKSTKKVKDMVRGHQMANMAGVRKLQPNLRVQPMVI
                     DPFAINELDYYLVSHFHSDHIDPYTAAAILNNPKLEHVKFIGPYHCGRIWEGWGVPKE
                     RIIVVKPGDTIELKDMKIHAVESFDRTCLVTLPVNGADETGGELAGLAVTDEEMAQKA
                     VNYIFETPGGTIYHGADSHFSNYFAKHGKDFKIDVALNNYGENPVGIQDKMTSIDLLR
                     MAENLRTKVIIPVHYDIWSNFMASTNEILELWKMRKDRLQYDFHPFIWEVGGKYTYPQ
                     DQHLVEYHHPRGFDDCFEQDSNIQFKALL"
     gene            18210..20186
                     /gene="tkt"
                     /locus_tag="VYO11_001280"
     CDS             18210..20186
                     /gene="tkt"
                     /locus_tag="VYO11_001280"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HEV1595847.1"
                     /translation="MSNLSVNAIRFLGIDAINKANSGHPGVVMGAAPMAYSLFTKQLH
                     INPAQPNWINRDRFILSAGHGSMLLYALLHLSGFEDVSMDEIKSFRQWGSKTPGHPEF
                     GHTAGIDATTGPLGQGISTATGFAQAERFLAAKYNREGYNIFDHYTYVICGDGDLMEG
                     VSSEAASYAGLQKLDKLVVLYDSNDINLDGETKDSFTESVRDRYNAYGWHTALVENGT
                     DLEAIHAAIETAKASGKPSLIEVKTVIGYGSPNKQGTNAVHGAPLGADETASTRQALG
                     WDYEPFEIPEQVYADFKEHVADRGASAYQAWTKLVADYKEAHPELAAEVEAIIDGRDP
                     VEVTPADFPALENGFSQATRNSSQDALNVVAAKLPTFLGGSADLAHSNMTYIKTDGLQ
                     DDTNRLNRNIQFGVREFAMGTILNGMALHGGLRVYGGTFFVFSDYVKAAVRLSALQGL
                     PVTYVFTHDSIAVGEDGPTHEPVEHLAGLRAMPNLNVFRPADARETQAAWYLAVTSEK
                     TPTALVLTRQNLTVEDGTDFDKVAKGAYVVYENAADFDTILIATGSEVNLAVSAAKEL
                     ASQGEKIRVVSMPSTDVFDKQDAAYKEEILPNAVRRRVAVEMGASQNWYKYVGLDGAV
                     LGIDTFGASAPAPKVLAEYGFTVENLVKIVRNLK"
     gene            20303..20602
                     /gene="yajC"
                     /locus_tag="VYO11_001281"
     CDS             20303..20602
                     /gene="yajC"
                     /locus_tag="VYO11_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HEV1595848.1"
                     /translation="MNPNITFLIMLVGMMALMFFMQRSQKKQAQKRMESLNKLQKGYE
                     VITIGGLYGTVDEVDTEKGTIVLDVDGVYLTFELAAIKTVLPLKETASLEGAIEK"
     gene            20649..21077
                     /locus_tag="VYO11_001282"
     CDS             20649..21077
                     /locus_tag="VYO11_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HEV1595849.1"
                     /translation="MKKLVFVCLGNICRSPMAEFVMKSMTDNYEIQSRATSSWEHGNP
                     IHKGTQGIFQQYEIPYDKNKTSLQISKEDFEAFDYIIGMDASNISDLRQMCPVDCQDK
                     IYSFSSESVPDPWYTGDFEETYRRVQEGCQAWLERLEKES"
     gene            21079..21489
                     /locus_tag="VYO11_001283"
     CDS             21079..21489
                     /locus_tag="VYO11_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000427064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1595850.1"
                     /translation="MENLTNFYEKYRVYLTRPRLELLAVVTIVFCAVLVFFLNIPGKG
                     VLKLDNGTIVYDGSLVRGKMNGQGTITFQNGDQYTGGFNNGAFNGKGTFQSKEGWTYE
                     GDFVNGQAEGKGKLTTEQEVVYEGTFKQGVFQQK"
     gene            21790..24441
                     /gene="adhE"
                     /locus_tag="VYO11_001284"
                     /gene_synonym="adhC"
     CDS             21790..24441
                     /gene="adhE"
                     /locus_tag="VYO11_001284"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HEV1595851.1"
                     /translation="MADKKTVTPEEKKLVAEKHVDELVQKALVALEEMRKLDQEQVDY
                     IVAKASVAALDAHGELALHAFEETGRGVFEDKATKNLFACEHVVNNMRHTKTVGVIEE
                     DDVTGLTLIAEPVGVVCGITPTTNPTSTAIFKSLISLKTRNPIVFAFHPSAQESSAHA
                     ARIVRDAAIAAGAPENCVQWITQPSMEATSALMNHEGVATILATGGNAMVKAAYSCGK
                     PALGVGAGNVPAYVEKSANIRQAAHDIVMSKSFDNGMVCASEQAVIIDKEIYDEFVAE
                     FKSYHTYFVNKKEKALLEEFCFGVKANSKNCAGAKLNADIVGKPATWIAEQAGFTVPE
                     GTNILAAECKEVGENEPLTREKLSPVIAVLKSESREDGITKARQMVEFNGLGHSAAIH
                     TADEELTKEFGKAVKAIRVICNSPSTFGGIGDVYNAFLPSLTLGCGSYGRNSVGDNVS
                     AINLLNIKKVGRRRNNMQWMKLPSKTYFERDSIQYLQKCRDVERVMIVTDHAMVELGF
                     LDRIIEQLDLRRNKVVYQIFADVEPDPDITTVNRGTEIMRAFKPDTIIALGGGSPMDA
                     AKVMWLFYEQPEVDFRDLVQKFMDIRKRAFKFPLLGKKTKFIAIPTTSGTGSEVTPFA
                     VISDKANNRKYPIADYSLTPTVAIVDPALVLTVPGFVAADTGMDVLTHATEAYVSQMA
                     SDYTDGLALQAIKLVFENLESSVKNADFHSREKMHNASTIAGMAFANAFLGISHSMAH
                     KIGAQFHTIHGRTNAILLPYVIRYNGTRPAKTATWPKYNYYRADEKYQDIARMLGLPA
                     STPEEGVESYAKAVYELGERIGIQMNFRDQGIDEKEWKEHSRELAFLAYEDQCSPANP
                     RLPMVDHMQEIIEDAYYGYKERPGRRK"
BASE COUNT         7819 a         4472 c         5466 g         7180 t
ORIGIN      
        1 aaaataggct ccataatatc tataagggat ttacccacta caaatattat agagccaaat
       61 atttttgtac ataagtaaat agaaattcag tcatccatca gatggctgga ttttttatca
      121 aaaaattaag aaatgagcat atttctttcc ttgtctggcg gaattggtta taatatacgg
      181 tacaaaggaa tgaatgaata tgtatcgtgt tatagaaatg tacggagatt ttgaaccgtg
      241 gtggttctta gaaggttggg aagaagatat tgtagcaagt agaaaatttg accagtatta
      301 tgatgctctc aaatactaca aaacttgctg gtttagattg gaacaagaat cccctcttta
      361 taaaagtaga agcgacttga tgaccatttt ttgggacccg gaagaccaac gctggtgtga
      421 tgaatgtgat gagtatttac aacaatacca ttctttggct cttttgcagg atgagcaggt
      481 tatcccagac gaaaaactac gctcaggcta tgaaaaacaa accagtcagg aaaggaatcg
      541 ttcttgccgt atgaaattaa aatagagaaa agtaactttt ttggagttgc tttttttatt
      601 tttctaacgc tttgcgaata gtataggtga ggaggtaagt atggttcaag aaattgcaca
      661 agaaatcatt cgctcggctc ggaaaaaagg ggcgcaagac atttattttg tccccaagtt
      721 agacgcctat gagcttcata tgagggtagg agacgagcgc tgtaaaattg gtagctatga
      781 ttttgaaaag tttgcagccg ttatcagtca ctttaagttt gtggcgggta tgaatgtggg
      841 agaaaaaaga cgtagtcaac tgggttcctg tgattatgcc tatgaccaga agatggcgtc
      901 tctacgttta tctactgtag gcgattatcg ggggcatgag agtttggtta tccgtttgtt
      961 gcacgatgag gagcaggact tgcatttttg gtttcaggat attgaagaat taggcaagca
     1021 gtacaggcaa cggggactct atctttttgc tggtccggtt ggaagtggta agacgacctt
     1081 gatgcatgga ttgtccaagt cactctttaa aggacagcaa gttatgtcca tcgaagatcc
     1141 tgtcgaaatc aagcaggacg atatgcttca gttgcagttg aacgaagcaa tcggcctaac
     1201 ctatgaaaat ctaatcaaac tttccttgcg tcatcgacca gatctcttga ttatcggaga
     1261 aattcgtgac agcgagacgg cgcgtgcagt ggtcagagct agtttgacag gtgcgacagt
     1321 cttttcaacc attcacgcca agagtatccg aggtgtttat gagcgtctgc tggagttggg
     1381 tgtgagtgaa gaagaattgg cagttgttct gcaaggagtc tgctaccaga gattaatcgg
     1441 gggaggagga atcgttgact ttgcaaacag agattatcaa gaacaccaag cagccaagtg
     1501 gaatgagcaa attgaccagc ttcttaaaga tggacatatc acaagtcttc aggctgagac
     1561 ggaaaaaatt agctacagct aagcaaaaaa atatcatcac cctatttaac aatctctttt
     1621 ctagcggttt tcatctggtg gagactatct cctttttaga taggagtgct ttgttggaca
     1681 agcagtgtgt gatccagatg cgtgcgggct tgtctcaagg gaaatcattc tcagaaatga
     1741 tggaaagttt gggatgttca agtaccattg tcactcagtt atccctagcc gaagttcatg
     1801 gaaatctcca cctgagtttg ggaaagatag aagaatatct ggacaatctg gctaaggtca
     1861 agaaaaaatt aattgaagta gcgacctatc ctttgatttt gctgggtttt cttctcttaa
     1921 ttatgctggg gctacggaat tacctgctcc cacaactgga tagtagcaat attgccaccc
     1981 aaattatcgg taatctgccc caaatttttc taggcatggt agggcttgtt tccgtgcttg
     2041 cccttttagc actaactttt tataaaagaa gttctaagat gagtgtcttt tctatcttag
     2101 cacgccttcc ctttattgga atctttgtgc agacctactt gacagcctat tatgcacgtg
     2161 aatgggggaa tatgatttca cagggaatgg agctgacgca gatttttcaa atgatgcagg
     2221 aacaaggttc ccagctcttt aaagaaatcg gtcaagatct ggctcaaacc ctgaaaaatg
     2281 gccgtgaatt ttctcagacg ataggaacct atcctttctt taggaaggaa ttgagtctca
     2341 tcatagagta tggggaagtt aagtccaagc tgggtagtga gttggaaatc tatgctgaaa
     2401 aaacttggga agcctttttt acccgagtca accgcaccat gaatttggtg cagccactgg
     2461 tttttatctt tgtggcactg attatcgttt tactttatgc ggcaatgctc atgcccatgt
     2521 atcaaaatat ggaggtaaat ttttaaaatg aaaaaaatga tgacattctt gaaaaaagct
     2581 aaggttaaag cttttacatt ggtggagatg ttagtagtct tgctgattat cagcgtgctt
     2641 ttcttgctct ttgtacctaa tctgaccaag caaaaagaag cagtcaatga caaaggaaaa
     2701 gcagctgttg ttaaggtggt ggaaagccag gcagaacttt atagcttgga taaaaatgaa
     2761 gatgctactc tgagcaagtt acaaggagat gggcgcatca cggaagaaca ggttaaagct
     2821 tataatgaat actatactaa aaatggaggg gcaaatcgta aagtcaatga ttaaggcctt
     2881 taccatgctg gaaagtctct tggttttggg acttgtgagt atccttgcct tgggcttatc
     2941 cagctctgtc cagtccactt ttgcagcagt agaggagcag attttcttta tggagtttga
     3001 agaactctat cgggaaaccc aaaaacgcag tgtagccagt cagcaaaaga ctagtctaaa
     3061 tttagatggg cagacgctta gcaatggcag tcaaaagttg acagttccta aaggaattca
     3121 ggcaccatca ggccaaagta ttacatttga ccgagctggg ggcaattcgt ccctggctaa
     3181 ggttgaattt cagaccagta aaggagcgat tcgctatcaa ttatatctag gaaatggaaa
     3241 aattaaacgc attaaggaaa caaaaaatta gggcagtgat tttactggaa gcagtagtcg
     3301 ctctagctat ctttgccagc attgcgaccc tccttttggg acaaattcaa aaaaataggc
     3361 aagaggaagc aaaaatcttg caaaaggaag aagtcttgag ggtagctaag atggccctgc
     3421 agacggggca aaatcaggta agcatcaacg gagttgagat tcaggtattt tctagtgaaa
     3481 aaggattgga ggtctaccat ggttcagaac agttgttggc aatcaaagag ccataaggtc
     3541 aaggctttta ccttgttaga atccctgctt gccctcattg tcatcagtgg gggattactc
     3601 ctttttcaaa ctatgagtca gctcctcatt tcagaagttc gctaccagca acaaagcgag
     3661 caaaaggagt ggctcttgtt tgtggaccaa cttgaggcag aattagaccg ttcgcagttc
     3721 gaaaaagtag aaggcaatcg cctatacatg aagcaagatg gcaaggacat cgccatcggt
     3781 aagtcaaagt cagacgattt tcgtaaaacc gatgctagtg gacgggggta tcagcctatg
     3841 gtttatggcc tcaaatcagc tcagattaca gaggacaatc aactggttca ttttcgtttc
     3901 cagtttcaaa aaggcttaga aagggagttc atctatcgtg tggaaaaaga agaaagttaa
     3961 ggcaggtgtt ctcctctacg cagtcaccat agcagccatc tttagtcttt tgttgcaatt
     4021 ttatttgaac cgacaaatcg cccactatca agactatgct ttaaataaag aaaaattggt
     4081 tgcttttgcc atggctaaac gaaccaagga taaagccgag caagaaagtg gggaacaggt
     4141 ttttaatcta ggtcaggtaa gctatcaaaa caagaaaaca agcttggtga cgactgttcg
     4201 tacgtctaag agccaatatg agtttctgtt tccttcagtc aaaatcaaag aagagaaaag
     4261 agataaaaag gaagaggtag cgaccgattc aagcgaaaaa gcggagaaaa aaaatcagaa
     4321 gagaagcctg aaaagaaaga gaattcctag tcaattcaac tataatgcgt tgaatccaga
     4381 atagtccact gtagtttcta gaaaattgct ggaaatggat gttaagctcc aattcatttg
     4441 tttatatctt atttcagttt actatacttt gtgctaaatt aaagatatga aacatgattt
     4501 taaccacaaa gcagaaactt tcgattcccc taaaaatatc ttcctcgcaa acttggtatg
     4561 tcaagcagcc gagaaacaga ttgatcttct atcagacaaa gaaattttag atttcggtgg
     4621 tgacacgggt ctattagcct tgcccctagc ccctagccaa gcaggctaag tcagtcactc
     4681 ttgtagacat ttctgagaaa atgttggagc aagctcgttt gaaagtggag cagcaagcaa
     4741 tcaagaatat ccagtttttg gagcaagatt taccgaaaaa tcccttggag aaagagtttg
     4801 atttccttgc tgttagtcgg gttcttcatc atatgcctga tttggatgcg gctctctcac
     4861 tgtttcatca acatttgaag gaagatggga aactcatcat tgctgatttt accaagacag
     4921 aagctaatca tcatggattt gatttagctg aactggaaaa caagctaatt gagcatggtt
     4981 tttcatctgt gcatagtcag attctctata gcgctgaaga cctgtttcaa ggaaatcact
     5041 cagaattctt tttaacagta gcccaaaaat cactcgccta gtcagggagt gatttttcta
     5101 taaggatgga aaaaagaagg gaaatttgat aagataggaa tatggatttt gaaaaaattg
     5161 aacaagctta tacctattta ctagagaatg tccaagtcat ccaaagtgat ttggcgacca
     5221 acttttatga cgccttggtg gagcaaaaca gcatctatct ggatggtgaa actgagctaa
     5281 accaggtcaa agacaacaat caggccctta agcgtttagc actacgcaaa gaagaatggc
     5341 tcaagaccta ccagtttctc ttgatgaagg ctgggcaaac agaacccttg caggccaatc
     5401 accagtttac accggatgct attgctttgc ttttggtgtt tattgtggaa gagttgttta
     5461 aagaggagga aattactatc ctcgaaatgg gttctgggat gggaattcta ggcgctactt
     5521 tcttgacctc gcttgataaa aaggtggatt acttgggaat ggaagtggat gatttgctga
     5581 ttgatctggc agctagcatg gcagatgtaa ttggtttgca ggctggcttt gtccaaggag
     5641 atgccgttcg tccacaaatg ctcaaagaaa gcgatgtggt catcagtgac ttgcctgtcg
     5701 gctattatcc tgatgacgcc gttgcgtcgc gccatcaagt tgcttctagc caagaacata
     5761 cttacgccca tcacttgctc atggaacaag ggcttaagta cctcaagtca gacggatacg
     5821 ctatttttct agctccgagt aatttgttga ccagtcctca aagtgatttg ttaaaagaat
     5881 ggctgaaaga agaggcgagt ctggttgcta tgattagtct gcctgaaaat ctctttgcta
     5941 atgctaaaca atctaagact atttttatcc tacagaagaa aagtgaaata gcagtggagc
     6001 cttttgttta tccacttgct agcttgcaag atgcaagtgt tttaatgaaa tttaaagaaa
     6061 attttcaaaa atggactcaa ggtactgaaa tataaaatag attttgttat aatagttgaa
     6121 aacgcttaaa aaggggtatc atgttatgac aaaaacaatt gcaatcaatg caggaagttc
     6181 aagtttgaaa tggcaattat acttaatgcc agaggaaaaa gtgttagcca aaggtttgat
     6241 tgaacgtatc ggtttgaaag attcaatttc aactgtaaaa tttgacggcc gttctgaaca
     6301 acaaattttg gatattgaaa atcatgcaca agccgttaaa attttattgg atgacttgat
     6361 tcgtttcgat attatcaagg cttatgacga gattacaggt gttggacatc gtgttgttgc
     6421 tggtggagaa tatttcaaag aatcaacagt tgttgaggga gatgttttag aaaaagttga
     6481 agagttgagt ttgttggctc ctctacacaa cccggccaat gcagcaggtg ttcgtgcctt
     6541 caaggaattg ttgccagaca ttaccagtgt agttgttttt gatacttcct tccacacaag
     6601 tatgccagag aaagcttatc gctaccctct accaacaaaa tattacacag aaaacaaggt
     6661 tcgtaaatac ggtgctcatg gtacaagtca ccagtttgta gcaggagagg ctgcaaaact
     6721 cttgggacgt ccattagaag acttgaagtt aattacctgt catattggta acggaggctc
     6781 aattacagct gtgaaagccg gcaaatctgt agacacttct atggggttca ctcctcttgg
     6841 tggtattatg atgggaacgc gtacagggga tattgatcca gctatcattc cttatttaat
     6901 gcaatataca gaggatttta acacaccaga agatatcagt cgtgttctta accgtgaatc
     6961 aggtcttttg ggagtttctg ctaattctag cgatatgcgc gatatagaag cagctgtagc
     7021 agaagggaat cacgaggcta gcttggctta tgaaatgtat gttgaccgta tccaaaaata
     7081 tatcggtcag taccttgcag tgctaaatgg agcagatgcc attgttttca cagcaggtgt
     7141 cggtgaaaat gcagagaatt tccgtcgtga tgtaatctca gggatttcgt ggtttggttg
     7201 tgatgttgat gatgaaaaga atgtctttgg cgttacagga gacatctcaa cagaggcagc
     7261 taaaatccgt gtcttggtta ttccaacaga tgaagaatta gtcattgccc gtgacgttga
     7321 acgcttgaaa aaataagtga aactaaaaaa atattcaata caaggagttg ggaaagttat
     7381 ttttccagct tctttttctg atgaaattgt ccaaaacctt gctatgattg gcttttttga
     7441 aaaatatggt ataatagtag taatttaata gatggagttg agttttgaag aaaaactttc
     7501 gtgtaaaaag agagaaagat tttaaggcga ttttcaagga ggggacaagt tttgctaatc
     7561 gcaaatttgt ggtctaccaa ttagaaaacc agaaaaacca ttttcgagta ggtctatcag
     7621 ttagcaaaaa actggggaat gccgtcacta gaaatcaaat taagcgacgg attcggcata
     7681 ttatccagaa tgcaaaaggg agtctggtag aagatgtcga ctttgttgtc attgctcgaa
     7741 aaggagtcga aaccttggga tacgcagaga tggagaaaaa tctactccac gtattaaaat
     7801 tatcaaagat ttaccaggaa ggaaatggga gtgaaaaaga aactaaagtt gactagtttg
     7861 ctaggactgt ctctgttaat catgacagcc tgtgcgacta atggggtaac tagcgatatt
     7921 acagccgaat cggctgattt ttggagtaaa ttggtttact tctttgcgga aatcattcgc
     7981 tttttatcgt ttgatattag tatcggagtg gggattattc tctttacgat cttgattcgt
     8041 acagtcctct tgccagtctt tcaggtgcaa atggtggctt ctaggaaaat gcaggaagct
     8101 cagccacgca ttaaggcgct tcgagaacaa tatccaggtc gagatatgga aagcagaacc
     8161 aaactagagc aggaaatgcg taaagtattt aaagaaatgg gtgtcagaca gtcagactct
     8221 ctttggccga ttttgattca gatgccggtt attttggccc tgttccaagc cctatcaaga
     8281 gttgactttt taaagacagg tcatttctta tggattaacc ttggtagtgt ggatacaacc
     8341 cttgttcttc cgattttagc agcagtattc acctttttaa gtacttggtt gtccaacaaa
     8401 gctttgtctg agcgaaatgg cgctacgact gcgatgatgt atgggattcc agtcttgatt
     8461 tttatctttg cagtttatgc gccaggtgga gtcgccctat actggacagt gtctaatgct
     8521 tatcaagtct tgcaaaccta tttcttgaat aatccattca agattatcgc agagcgcgag
     8581 gccgtagtac aggcacaaaa agatttggaa aatagaaaaa gaaaagccaa gaaaaaggct
     8641 cagaaaacga aataaataag gaggaatctg gtaatggtag tatttacagg ttcaactgtt
     8701 gaagaagcaa tccagaaagg attgaaagaa ttagatattc caagaatgaa ggctcatatc
     8761 aaagtcattt ctagggagaa gaaaggcttt cttggtctat ttggtaaaaa accagcccaa
     8821 gtggatattg aaacgattag tgaaacgact gttgtcaaag caaatcaaca ggtagtaaaa
     8881 ggcgttccga aaaaaatcaa tgatttgaac gagcctgtga agacggttag tgaagaaacc
     8941 gttgaccttg gtcatgtggt tgatgctatt aaaaaaatag aggaagaagg tcaaggcatt
     9001 tctgatgaag tcaaggctga aatcttaaaa catgaaagac atgccagcac tatcttagaa
     9061 gaaactggtc acattgagat tttaaatgaa cttcaaatcg aggaagcgat gagggaagaa
     9121 gcaggcgctg atgaccttga aactgagcaa gaccaagctg aaagtcaaga actagaagac
     9181 ttgggcttga aagttgaaac gaactttgat attgaacaag tagctacgga agtaatggct
     9241 tatgttcaaa cgattattga tgacatggat gttgaggcta cactttcaaa tgattataac
     9301 cgtcgtagca tcaatttgca aattgatact aacgaaccag gtcgtattat cggctaccat
     9361 ggtaaagtct tgaaggcctt gcaactgttg gctcaaaatt atctttacaa ctgctattca
     9421 agaaccttct atatcactat taatgtcaat gattatgttg aacaccgtgc agaagtcttg
     9481 cagacctatg cgcaaaaatt ggcgattcgt gttttagaag aaggacgtag tcatcaaaca
     9541 gatccaatgt cgaatagtga acgcaagatt atccaccgta ttatttcacg tatggatggc
     9601 gtgaccagtt actctgaagg tgatgagcca aatcgctatg tcgttgtaga tacagaataa
     9661 gtaaaatcag ggttgacctg attttttgct agctagagga ggttaaactg atgttgaata
     9721 agataagaga ctatctagac ttttctggtt tgcagtaccg tagtcctgat aaagcggggg
     9781 cagagcgaga gaagatgctg gcgttccgcc acaaaggaca agaggcccga aaggctttta
     9841 cagaactggc caaagccttt caagcaagcc atccagaatg gcaactccaa cagactagtc
     9901 agtggatgaa tcaggcccag cgtttgagac cacatttttg ggtttatcta cagagagacg
     9961 gacaagtgac agaacctatg atggccttac gtttgtatgg gacatctact gactttggaa
    10021 tttctttgga agtcagtttc atcgaacgta agaaggatga gcaaacttta gagaaacagg
    10081 ccaagatttt agacatacca accgttaaag gaatttatta tctagcctac tctgatggcc
    10141 aaagtcaacg gtgggaggcg aacgaagaaa agcgtcgtac tttacgcgag aaggtgagaa
    10201 gtcaagaagt tcgaaaagtt ttagtgaagg tagatgttcc tatgacagaa aattcgtctg
    10261 aagaagaaat cgtagaaggc ttattgaagt cttattctaa aattcttccc tattatctag
    10321 ctacgagaaa ataagataat ttgtaaaaca tcataaatca tacagtccaa gagtgaacag
    10381 tccgctgtgt aattcttggt ctttttgttt gcgctttcgc attatataat aaacttacaa
    10441 aaacaattca aaaggagaac aattatggaa gtcgtttcaa gtgttctaaa ttggttttct
    10501 agcaatattt tgcagaatcc cgcatttttc gtaggtttat tggtgttgat aggatatgca
    10561 cttttgaaaa aacctgccca tgacgttttt tcagggtttg ttaaagcaac agtagggtat
    10621 atgttgctta acgtgggtgc tggtggtttg gttacaacct ttcgtccaat cttagcagct
    10681 cttaactaca aattccaaat tggtgcagcg gttatcgacc cttactttgg acttgctgca
    10741 gcaaacaaca aaattgcagc agagtttcca gattttgttg gaactgcaac tacagctcta
    10801 ttgattggtt ttggaataaa tatcttgctc gtagctcttc gaaagattac gaaggtaaga
    10861 accctcttta ttactggtca catcatggta caacaagctg caacagtatc tcttatggtt
    10921 ctattcttag taccacaatt gcgcaatgct tacggtacag cagcgattgg tatcatctgt
    10981 ggactttact gggcagttag ttcaaatatg actgttgagg caactcaacg cttgactggt
    11041 ggtggcggat ttgcgattgg tcaccaacag caatttgcaa tctggtttgt agataaagta
    11101 gcaggacgct ttggtaagaa agaagaaagt ttagacaatc ttaaattacc taagttcctc
    11161 tcaatcttcc acgatacagt tgttgcatct gctaccttga tgctcgtatt cttcggggcc
    11221 attcttttaa tcttgggtcc agacattatg tctaataaag aagtcatcac ttcaggaact
    11281 ctattcaatc ctgctaaaca agatttcttt atgtacatta tccaaacagc ctttaccttc
    11341 tcagtttact tgttcgtttt gatgcaaggt gtccgaatgt tcgtatctga gttaacaaac
    11401 gctttccaag gtatttcaaa caaattgttg ccaggttcat tcccagcggt tgacgttgca
    11461 gcttcttatg gatttggttc tccaaatgct gtcttgtcag gatttacctt tggtttgatt
    11521 ggtcaattga ttacaattgt cttgctcatc gtctttaaaa atccgattct tattattaca
    11581 ggatttgtac cagtgttctt tgacaatgca gccattgcgg tctacgctga taaacgcggc
    11641 ggatggaaag cggctgttat cctttccttt atatcaggtg tccttcaagt tgctctagga
    11701 gctctttgtg tggcccttct cgatttggca tcttatggtg gctaccatgg aaatatcgac
    11761 tttgaattcc catggcttgg atttggatat atcttcaaat accttggtat tgttggttat
    11821 gtacttgtgt gtctcttctt gcttgttatt cctcaacttc aatttgccaa agcaaaagat
    11881 aaagagaaat attacaacgg tgaagttcaa gaagaagctt agtatctaga aaaggagaaa
    11941 taaaatggtt aaagtattag cagcgtgcgg aaatggaatg ggttcatcaa tggttatcaa
    12001 gatgaaggtt gaaaatgctc tccgtaagct taatcaaaca gattttacag tcaattcatg
    12061 cagtgtcggt gaagctaaag gtttagcagt aggatatgac atcgtaatcg cttctcttca
    12121 tttgattcaa gaattggaag ggcgaactaa tgggaagtta attggacttg ataacttgat
    12181 ggatgataaa gaaatcaccg aaaaactcag tcaagcacta cagtaaaagg ttggaggggg
    12241 ctggacagaa actgagagtt atcgtttctg tccttctccc tctttaaata aaggaggcag
    12301 atatgaattt aaaacaagct ttaattgaca atgactcgat ccgactaggt ttagaggcta
    12361 acgattggaa agaagcagtc aaggtagcag tagatccctt gattgaaagt ggggcaattt
    12421 tgccagagta ttacgatgct atcattgaat cgactgaaga gtatgggcct tactatatct
    12481 tgatgccagg tatggctatg ccccacgcta gacctgaagc tggtgtgcaa agtgatgcct
    12541 tttcattaat taccttacaa aatcctgttg tattttcaga tgggaaagag gtatctgttt
    12601 tgttggcact agcagcaaca agttcaaaaa ttcacacaag tgtagccatt ccacaaatta
    12661 ttgccctgtt tgaattagaa gattctattg cacgtttaca ggcttgccag actaaagaag
    12721 atgtcttggc tatgattgaa gaatctaagg atagccctta tctcgaagga ttggatttgg
    12781 aaagttagaa agaggaataa agaaatgaca aaaagaatac ctaatttaca agttgcatta
    12841 gaccattcag acttgcaagg agcgattaaa gcagctgttt ctgttggtca ggaagtagat
    12901 attatcgaag ctggaactgt ttgcttgctt caagttggaa gtgaactggc tgaagtcttg
    12961 cgtagccttt tcccagataa gattattgtg gcagacacaa aatgtgctga tgctggtgga
    13021 acagttgcta aaaataatgc ggttcgtgga gcagactgga tgacttgtat ctgttgtgca
    13081 accatcccta ctatggaagc agctctaaag gctatcaaga ctgaacgagg agaacgaggc
    13141 gaaatccaga tcgagcttta tggcgattgg acttttgaac aagctcagct ttggctagat
    13201 gcaggtatct cacaagctat ttatcaccaa tctcgtgatg ctcttcttgc tggtgaaact
    13261 tggggtgaaa aagaccttaa taaggttaaa aaactcattg acatgggctt ccgtgtatct
    13321 gtaacaggtg gtctagatgt agatactctc aaactctttg aaggtgttga tgtctttacc
    13381 tttatcgcag gtcgtggaat tacagaggct gtggatccag caggagcagc gcgtgccttc
    13441 aaggatgaaa tcaaacgaat ttgggggtaa atcatggtac gtccaattgg aatttatgaa
    13501 aaggcaaccc caacacactt tacttggcta gaacgtttaa attttgccaa ggagttaggc
    13561 tttgatttta tcgagatgtc tattgacgaa cgtgacgagc gtttagcaag acttgactgg
    13621 agtaaggaag aacgcttgga agttgtcaaa gaaatctatg aaactggtgt tcgtattcct
    13681 tctatctgtt tttcaggcca tcgtcgctac ccattgggat caaaagattc agttctagag
    13741 gaaaaatctc tagaactcat gaaaaaatgt atcgaattag ctcaagactt gggagttcgt
    13801 acgattcaat tagctggtta cgatgtttac tatgaggaaa agtcacccca gacacgccaa
    13861 cgttttatca aaaatttgag aaaagcctgt gactgggctg aagaagctca ggtggtactt
    13921 gctattgaaa ttatggatga tcctttcatc aatagcatcg aaaaatattt ggctatagaa
    13981 aaagagattg actctccctt cctctttgta tatccagata ttggtaatgt gtctgcatgg
    14041 cataatgata tctatagtga gttttatctt ggtcatcatg ccatcgcagc tctccatctc
    14101 aaggatactt atgcagtgac agaaagttca aagggccagt tccgagatgt accttttggg
    14161 caaggttgtg tcaaatggga agaagctttc gatattttaa aggaaaccaa ttataatgga
    14221 cctttcctaa tcgaaatgtg gtctgaaaat tgtgaaacag tagaagaaac acgcgcagcc
    14281 attcaagagg cgcaagcttt tctctatcca ctcattaaga aagcaggttt gatgtaagat
    14341 gaatcaagta atcaatgcta tgcgtaaacg agtctgtgat gccaatcaat cattgccaaa
    14401 acatggactt gtcaaattta cctgggggaa tgtatctgaa gtcaatcgcg aactcggtgt
    14461 cattgttatc aaaccatcag gcgtggatta tgacgaattg acacctgaaa acatggtagt
    14521 gactgatcta gatggtaaga tcctagaagg ggatttaaga ccatcttccg acctcccaac
    14581 tcatgtgcaa ttatataagg cttggtcaga aattggtagt gtggttcaca cccattcgac
    14641 agaagctgtt gcttgggctc aggcaggtcg tgatattcct ttctacggaa caacccatgc
    14701 agattatttc tacggttcaa tcccttgcgc ccgtagtttg accaaggacg aagtagaagt
    14761 ggcctatgaa aaagatactg gcctggttat cgtagaagag tttgaacatc gcggacttaa
    14821 cccggttgaa gtaccaggaa ttgttgtacg caatcacggt ccattcacct ggggcaaaaa
    14881 tccagagaat gctgtttatc actctgtcgt actagaggaa gtatcaaaga tgaatcgctt
    14941 tacagaacaa atcaatccaa gagttgaacc tgctccccag tacatactag aaaaacacta
    15001 ccaacgtaaa catggaccaa atgcttatta tggtcaaaag taagaacgat gaaggaggag
    15061 aaaaagataa atttagctcc tctttttaca tttgattttt attgagagta aagttggagt
    15121 tgaagtaatt ttgaaagatt ttttagaaat agcgcttgat atatatggta aaataaaaag
    15181 aattgctgtg atatcaatag atttggggga ttttttaata tggtactgga taaggcaagt
    15241 tgtgatttgc ttcaatattt gatggatcaa gaaacgtcca aaacgattat ggcgatttcg
    15301 aaagatttga aagagtcaag aaggaaaatt tattatcaca ttgacaaaat caatgctgct
    15361 ctggttgacg aggcgcttca catcattagt attccacgaa ttggtattca cttaacggaa
    15421 gagcagagag atgcttgttg taaactatta tcggaagtag attcgtacga ttatatcatg
    15481 agtgcgcatg aacgtatgat gataatgtta ctatggatag gtatttctaa agaacgtatt
    15541 actattgaaa aattgataga gttaacagag gtatctagga atactgttct caatgatttg
    15601 aatagtattc gttatcaact aactttggaa caatatcagg tgaccttgca agtgagcaag
    15661 tcacagggat accaccttca tgcccaccct cttaataaaa ttcagtatct tcaatcgctt
    15721 ctatatcata tttttatgga agaaaatgcc acttttgtat ctattttaga agataagatg
    15781 aaagagaggt tagatgatga gtgtttgctt tctgttgaaa tgaaccaatt ttttaaggaa
    15841 caggttcctt tagttgaaca agatttaggg aagaaaataa accatcatga aataactttt
    15901 atgttgcagg ttctacctta tttgctgtta agctgtcata atgttgaaca gtatcaagaa
    15961 agacatcagg atatagagaa agaattttct ttgataagaa aaagaataga gtatcaggtg
    16021 tctaagaaat taggagaacg gttgtttcaa aagtttgaaa tttctttgtc aggacttgaa
    16081 gtttctcttg tagctgttct cctcctctcc tatcgtaaag atttggatat tcatgcagaa
    16141 agtgatgatt ttcggcaatt aaaacttgct ttagaagaat ttatctggta ttttgaatca
    16201 caaatccgaa tggagattga gaacaaggat gatttgttac gaaatttgat gatccactgt
    16261 aaagccttgt tatttagaaa gacttacggt attttttcta aaaatcctct aacaaaacaa
    16321 attcgatcca agtatggaga attattttta gtcactagaa aatctgcgga aattttagaa
    16381 ggagcatggt ttattcggct aacagacgat gatattgcct atttgacgat tcatattgga
    16441 ggatttttaa agtatacacc atcgtctcaa aaaaatatga aaaaagttta tctcgtttgt
    16501 gatgaaggtg ttgcggtttc gagacttttg ctgaaacaat gcaaacttta ttttccaaat
    16561 gagcaaattg acactgtatt tacaacagaa caatttaaga gtgtggaaga tattgcacaa
    16621 gttgatgtag tgattactac taatgatgat ttggatagca gatttccgat tttaagggtt
    16681 aatcctatcc ttgaagcaga agatattttg aaaatgctag actatcttaa acacaatata
    16741 tttcgtaata agagcaaaag tttcagtgaa aatctttcta gtcttatttc gtcttatatt
    16801 gtagacagca agttggctag taagttccaa gaagaggttc aaacacttat aaataaagaa
    16861 atagtagttc aagctttttt ggaagatatt tgaaggacag tccaatgatg aacacaaacc
    16921 tgtgtttttc ttggtctttt ttagtgtttt gaagggtggt atactaatct caaagataac
    16981 aattatatcc aaaggaggca acatatgcca aacgtcaaag aaattacaag agagtcatgg
    17041 attttagcca ctttcccaga gtggggaaca tggttgaacg aagaaatcga agaagaagtc
    17101 gtacctgaag gcaactttgc catgtggtgg ctaggcaact gtggtacttg gattaagaca
    17161 ccagctggtg ctaacgttgt catggacctt tggtcaaacc gtggaaaatc aaccaaaaaa
    17221 gtgaaagata tggttcgtgg gcaccaaatg gcaaatatgg caggtgttcg taagttgcaa
    17281 ccaaacttgc gtgttcagcc aatggttatc gatccatttg ctatcaacga actagactat
    17341 tacttagttt cacacttcca cagtgatcat atcgacccat acacagctgc agcaattctc
    17401 aacaatccta agttagagca tgttaagttt atcggtcctt accactgtgg acgaatctgg
    17461 gaaggatggg gtgttccaaa agaacgtatc atcgttgtta aaccaggtga cactatcgaa
    17521 ttaaaagata tgaagattca tgcagtagaa tcatttgacc gtacttgctt agtaactctc
    17581 ccagtgaacg gtgctgatga gacaggcggt gaacttgctg gcttggctgt tacagatgaa
    17641 gaaatggctc aaaaggctgt taactatatc tttgaaacac caggtggaac catctatcat
    17701 ggtgcagatt ctcacttctc aaactatttt gcaaaacatg gtaaagactt taaaattgat
    17761 gttgctttga ataactatgg tgaaaatccg gtaggtatcc aagacaaaat gacatctatc
    17821 gaccttcttc gtatggcaga aaatctgcgt accaaagtca ttatcccagt tcactatgat
    17881 atctggtcta acttcatggc ttctactaat gagattctag aactttggaa aatgcgaaaa
    17941 gatcgcttgc aatacgattt ccatccattt atctgggaag ttggcggtaa gtacacttat
    18001 cctcaagatc aacacttagt agaataccat catccacgtg gttttgatga ttgttttgaa
    18061 caagactcta acattcaatt taaagctttg ctataatata aaaatattct ttggaggtta
    18121 tccgtatgtt gcatgatacg gataattttc atataatagt aaaatagaat gtgtgattca
    18181 ataatcacct caaatagaaa ggaaattcta tgtcaaatct atctgttaat gcaattcgtt
    18241 ttctaggtat tgacgccatt aataaagcca actcaggtca tccaggtgtg gttatgggag
    18301 cggctccgat ggcttacagc ctctttacaa aacaacttca tatcaatcca gctcaaccaa
    18361 actggattaa ccgcgaccgc tttattcttt cagcaggtca tggctcaatg ctcctttatg
    18421 ctcttcttca cctttctggt tttgaagatg tcagcatgga tgagattaag agcttccgtc
    18481 aatggggttc aaaaacacca ggtcacccag aatttggtca tacggcaggg attgatgcta
    18541 cgacaggtcc tctagggcaa gggatttcaa ctgctactgg ttttgcccaa gcagaacgtt
    18601 tcttggcagc caaatataac cgtgaaggct acaatatctt tgaccactat acttacgtta
    18661 tctgtggaga cggagacttg atggaaggtg tctcaagcga ggcagcttca tacgcaggct
    18721 tgcaaaaact tgataagttg gttgttcttt atgattcaaa tgatatcaac ttggatggtg
    18781 agacaaagga ttcctttaca gaaagtgttc gtgaccgtta caatgcctac ggttggcata
    18841 ctgccttggt tgaaaatgga acagacttgg aagccatcca tgctgctatc gaaacagcaa
    18901 aagcttcagg caagccatct ttgattgaag tgaagacggt tattggatac ggttctccaa
    18961 acaaacaagg aactaatgct gtacacggcg cccctcttgg agcagatgaa actgcatcaa
    19021 ctcgccaagc cctcggttgg gactacgaac catttgaaat tccagaacaa gtatatgctg
    19081 atttcaaaga acatgttgca gaccgtggcg catcagctta tcaagcttgg actaaattag
    19141 ttgcagatta taaagaagct catccagaac tggctgcaga agtagaggcc atcatcgacg
    19201 gacgtgatcc agtcgaagtg actccagcag acttcccagc tttagaaaat ggtttttctc
    19261 aagcaactcg taattcaagt caagatgcct tgaatgttgt ggcagctaaa ttaccaacct
    19321 tcctaggtgg atcagctgac cttgctcact caaacatgac ttatatcaag acggatggac
    19381 ttcaagacga taccaatcgc ttgaatcgta acattcagtt tggtgttcgt gaatttgcaa
    19441 tgggaacaat cttgaacggg atggcccttc atggtggact tcgtgtatac ggtggaactt
    19501 tcttcgtctt ctctgactat gtgaaggcag ctgtccgctt gtcagcctta caaggacttc
    19561 ctgtgactta tgtctttacc catgattcaa tcgcagttgg ggaagatggt ccgactcacg
    19621 aaccagttga gcatttagca ggtcttcgtg ctatgccaaa tctaaatgtt ttccgtccag
    19681 cagatgcgcg tgaaactcaa gcagcttggt accttgcagt gacaagtgag aaaacaccaa
    19741 ctgcccttgt cttgacacgt caaaacttga ctgttgaaga tggaacagac ttcgacaagg
    19801 ttgctaaagg tgcttatgtt gtatatgaaa atgcagccga ctttgatacc atcttgattg
    19861 cgacaggttc agaggttaat cttgctgtct cagctgctaa agaattggct agtcaaggcg
    19921 aaaaaatccg cgtagtcagc atgccatcta cagatgtctt tgataaacaa gatgcagctt
    19981 acaaggaaga aattcttcca aatgcagtcc gccgtcgtgt tgcagtcgaa atgggtgcaa
    20041 gtcaaaactg gtacaaatat gttggtctcg atggtgccgt tctaggtatt gataccttcg
    20101 gagcctctgc cccagcacca aaagtattgg cagaatatgg ctttactgta gaaaatcttg
    20161 taaaaattgt tcgaaacttg aaataatcct aaaaatcagg gcgtaagctc tggtttttct
    20221 taccagaaaa gtaaggtaca atcttgtaaa agtagctgaa atttgatata gtagtcctat
    20281 gtaaaagaca aaggagaaaa caatgaatcc aaatattact tttttaatca tgcttgtagg
    20341 tatgatggcc ttgatgttct ttatgcaacg ttctcaaaag aaacaagctc aaaagcgtat
    20401 ggaaagctta aataaactac aaaaaggcta tgaagtgatt acaatcggtg gactttatgg
    20461 aacagtcgat gaagtagata cggagaaggg aacaatagtt cttgacgtag atggagttta
    20521 cttgactttt gaactagctg ctatcaagac agtattaccg ctgaaagaaa cagcttcact
    20581 agaaggcgca attgaaaaat aagacgggat cacgaactcc cgtttttcta taaaagaaag
    20641 gaaatgggat gaaaaaatta gtctttgtct gtctgggaaa tatttgccgt agccctatgg
    20701 ccgagtttgt tatgaaatca atgacagata actacgaaat ccaaagtcga gcaacttcct
    20761 cttgggaaca tggcaatccg attcataagg ggactcaggg aatttttcaa cagtatgaga
    20821 ttccttatga caagaacaag acatcgcttc agattagtaa ggaagatttt gaagcctttg
    20881 attatattat cggaatggac gcttcaaata tttctgactt acgtcagatg tgtccagtag
    20941 actgtcaaga taagatttac tcattttcat ctgaaagtgt tccagaccct tggtatacag
    21001 gagattttga agaaacctat cgacgtgttc aagagggctg tcaagcttgg ttagaacgtt
    21061 tagaaaagga gagttaaggt ggaaaatctt acgaattttt acgaaaagta tcgtgtctat
    21121 ctgactcgtc cacgtttaga gcttttggca gtagttacca ttgttttctg tgctgtactc
    21181 gtcttttttc taaatattcc aggaaaaggt gtcttaaaac tcgataatgg aacgattgtt
    21241 tatgatggca gtcttgtccg tggtaaaatg aatggtcaag gtaccattac cttccaaaat
    21301 ggagaccaat atacaggtgg cttcaacaat ggagccttca acggaaaagg tacctttcaa
    21361 tctaaagaag gctggaccta cgaaggtgat tttgtaaatg gtcaggctga aggaaaaggg
    21421 aaactaacaa cagaacaaga agtcgtttat gaaggaactt ttaaacaagg cgtttttcaa
    21481 caaaaataaa gcctccttat ccaaaggagg tattattaga accacaaggt aagcgcttac
    21541 ctgtaaatcc ctttctttcc aaatccctct tccaagcaag tttgtgaaat aaaaaatatt
    21601 tgaaataaat ttcacaaact tcaaagataa aacctgataa gaaaagaaaa tgagaaaagt
    21661 ttcacaagag tttaaaaatt ctttgtgaaa tgtttatgaa actgtttaca aagttgaaat
    21721 aatgcgttat aataaacttg tgaaaaaatt aacaaaggat atcgttcctt gaaagctatg
    21781 gaggaaaata tggctgataa aaaaactgtg acaccagagg aaaagaaact cgttgctgaa
    21841 aaacacgtag atgagttggt tcaaaaagct ctagttgccc ttgaagaaat gcgtaaattg
    21901 gatcaagagc aagttgacta catcgttgcc aaagcatcag tagcagcttt ggatgcccac
    21961 ggagaattgg ctttacatgc ctttgaagaa acaggacgtg gtgtatttga agacaaagca
    22021 actaagaact tgtttgcctg tgaacacgta gtaaacaaca tgcgccacac taagacagtt
    22081 ggcgttatcg aagaagacga tgtaacagga ttgactctta ttgctgaacc agttggtgtt
    22141 gtttgtggta ttactccaac aacaaaccca acatcaacag caattttcaa atcattgatt
    22201 tcattgaaga cacgtaaccc aatcgtcttt gccttccatc catcagcaca agaatcatct
    22261 gctcatgcag ctcgtatcgt ccgcgatgca gctatcgcag ctggtgctcc tgaaaactgt
    22321 gtgcaatgga ttactcaacc atctatggaa gcaacaagtg cccttatgaa ccacgaaggg
    22381 gttgcgacaa tccttgcaac aggtggtaat gccatggtta aggcggctta ttcatgtggt
    22441 aaaccagctc ttggggtagg tgccggaaac gttccagctt atgttgaaaa atcagcaaac
    22501 attcgtcaag cagcacacga tatcgtcatg tctaaatcat ttgataacgg tatggtctgt
    22561 gcatctgaac aagcagttat cattgataaa gaaatttacg atgaatttgt agcagagttc
    22621 aaatcttacc acacttactt tgtaaacaaa aaagaaaaag ctcttcttga agagttctgc
    22681 ttcggcgtca aagcaaacag caaaaactgt gctggtgcaa aattgaacgc tgacatcgtt
    22741 ggtaaaccag caacttggat tgcagaacaa gcaggattta cagttccaga aggaacaaac
    22801 attcttgctg cagaatgtaa agaagttggc gaaaatgagc cattgactcg tgaaaaattg
    22861 tcaccagtta ttgcagtttt gaaatctgaa agccgtgaag atggtattac taaggctcgt
    22921 caaatggttg aatttaacgg tcttggacac tcagcagcta tccacacagc tgacgaagaa
    22981 ttgactaaag aatttggtaa agctgttaaa gctattcgtg ttatctgtaa ctcaccttct
    23041 acttttggtg gtatcgggga cgtttacaat gccttcttgc catcattgac acttggatgt
    23101 ggttcttacg gacgcaactc agttggggat aacgttagtg ccattaacct cttgaatatc
    23161 aaaaaagtcg gaagacggag aaataacatg caatggatga aacttccttc aaaaacatac
    23221 tttgaacgtg attcaattca ataccttcaa aaatgtcgtg acgttgaacg tgtcatgatc
    23281 gttactgacc atgccatggt agagcttggt ttccttgatc gtatcatcga acaactggac
    23341 cttcgtcgca ataaggttgt ttaccaaatc tttgcggatg tagaaccgga tccagatatc
    23401 acaactgtaa accgtggtac tgagattatg cgtgccttca aaccagatac catcatcgca
    23461 ctcggtggtg ggtctccaat ggatgctgcc aaagtaatgt ggctcttcta cgagcaacca
    23521 gaagtggact tccgtgacct tgtccaaaaa ttcatggata tccgtaaacg tgccttcaag
    23581 ttcccattgc ttggtaagaa gactaaattc atcgcgattc caactacatc tggtacagga
    23641 tctgaagtaa caccatttgc cgttatctct gataaagcaa acaaccgtaa atacccaatc
    23701 gctgactact cattgacacc aactgtggca atcgtagatc ctgctttggt attgacagtt
    23761 ccaggatttg ttgctgctga tactggtatg gacgtattga ctcacgcgac agaagcatac
    23821 gtatcacaaa tggctagtga ctacactgat ggtttagcac ttcaagccat taaattggtc
    23881 tttgaaaatc tcgaaagctc agttaagaat gcagacttcc actcacgtga gaaaatgcat
    23941 aacgcttcaa caatcgctgg tatggccttt gccaatgcct tcctaggtat ttctcactca
    24001 atggcccata agattggtgc gcaattccac acaatccacg gtcgtacaaa tgctatcttg
    24061 cttccatacg ttatccgtta caacggtaca cgtccagcta agacagcaac atggcctaag
    24121 tacaactact accgtgcaga tgaaaaatac caagatatcg cacgcatgct tggacttcca
    24181 gcttctactc cagaagaagg ggttgaatct tacgcaaaag ctgtctacga actcggtgaa
    24241 cgtattggga tccaaatgaa ttttagagac caaggaattg acgaaaaaga atggaaagaa
    24301 cattctcgtg aattagcctt cctggcttat gaagaccaat gttcaccagc taacccacgt
    24361 cttccaatgg tagaccatat gcaagaaatc atcgaagatg catactatgg ctacaaagaa
    24421 agaccaggac gccgtaaata attgtttatc agtctagaag caagacaaaa actcaatttg
    24481 agggaaagat ccagtaattt ttctatgata aaaggcatcc tatcaaggtt tttgaacacc
    24541 tgataggatg cctttttatg atattgaggc ctttttgccc tttttgaaaa actagaatag
    24601 aaacaaaata tataatagat tgaaactaga gtagtacaca tctgcttcta aaacattgtt
    24661 agaattcgat ttgactgtcc tgatcaattt gtcctgttct tatttcattt taatatatat
    24721 aaaatatagt atagtagact gaatctaaaa tagtacgaaa caattgctaa aacatttata
    24781 gaaattaatt ttacttttct gatagagttg ttcacatctt atttcaattc actatagttt
    24841 aatttaagag tagtatttac taaggcccaa ttaaaatcaa agagcaaact agaaaacgag
    24901 tgccattcag ctcaaaacac tgatttgaga ttgcaga
//
LOCUS       DAVLXH010000029        24461 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00028199
            SAMN33607166-rid17955573.denovo.029, whole genome shotgun sequence.
ACCESSION   DAVLXH010000029 DAVLXH010000000
VERSION     DAVLXH010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607166
            Sequence Read Archive: SRR23725544
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 24461)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24461)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721421.1
            Genome Coverage       :: 115x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:42:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,210
            CDSs (total)                      :: 2,161
            Genes (coding)                    :: 2,023
            CDSs (with protein)               :: 2,023
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 73 of 138
            Pseudo Genes (incomplete)         :: 60 of 138
            Pseudo Genes (internal stop)      :: 40 of 138
            Pseudo Genes (multiple problems)  :: 31 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24461
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607166-rid17955573.denovo.029"
                     /strain="AUSMDU00028199"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1349"
     gene            94..1725
                     /locus_tag="VYO11_001285"
     CDS             94..1725
                     /locus_tag="VYO11_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HEV1595852.1"
                     /translation="MSINWQEILFHFLGGLGLFLYSIKTMGDGLQQAAGDRLRFYIDK
                     YTSNPFFGVLVGIGMTALIQSSSGVTVITVGLVSAGLLTLRQAIGIVMGANIGTTVTS
                     FLIGFKLGNYALPMLFIGAVCLFFTKNRTVNNIGRILFGVGGIFFALNLMSGAMAPLK
                     DLQVFKDYMIELSKNPVLGVFVGTGLTLLIQASSATIGILQNLYAGNLIDLQGALPVL
                     FGDNIGTTITAIIASLGANIAAKRVAGAHVAFNVIGTVVCVIFLVPFTVLIHWFEATL
                     NLAPEMTIAFAHGTFNITNTIVQFPFIGALAYFVTKIIPGEDEVVKYEPLYLDEHFIK
                     QAPSIALGNAKKELLHLGNYAAKAFDLSYKYIIDLDEKVAEKGHKTEEAINTIDEQLT
                     RYLIALSSEALSQKESEVLTNILDSSRDLERIGDHTEALLNLTDYLQRKNVEFSDAAL
                     KELEEVYRQTSDFIKDALDSVENNDIEKARSLVERHEAINKIERVLRKTHIKRLNKGE
                     CSTQAGVNFIDIISHYTRVSDHAMNLAEKVFAEQI"
     gene            complement(2266..3873)
                     /locus_tag="VYO11_001286"
     CDS             complement(2266..3873)
                     /locus_tag="VYO11_001286"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HEV1595853.1"
                     /translation="MSTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPY
                     INIDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRK
                     ERRGEYLGATVQVIPHITDALKEKIKRAALTTDSDVIITEVGGTVGDIESLPFLEALR
                     QMKADVGADNVMYIHTTLLPYLKAAGEMKTKPTQHSVKELRGLGIQPNMLVIRTEEPA
                     GQGIKNKLAQFCDVAPEAVIESLDVEHLYQIPLNLQAQGMDQIVCDHLKLDAPAADMT
                     EWSAMVDKVMNLKKQVKISLVGKYVELQDAYISVVEALKHSGYVNDVEVKINWVNAND
                     VTAENVAELLSDADGIIVPGGFGQRGTEGKIQAIRYARENDVPMLGVCLGMQLTCIEF
                     ARHVLGLEGANSAELAPETKYPIIDIMRDQIDIEDMGGTLRLGLYPSKLKRGSKAAAA
                     YHNQEVVQRRHRHRYEFNNAFREQFEAAGFVFSGVSPDNRLVEIVEIPENKFFVACQY
                     HPELSSRPNRPEELYTAFVTAAVENSN"
     gene            complement(4263..4850)
                     /locus_tag="VYO11_001287"
     CDS             complement(4263..4850)
                     /locus_tag="VYO11_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HEV1595854.1"
                     /translation="MELEVFAGQEKSELSMIEVARAILELRGRDHEMHFSDLVNEIQN
                     YLGTSNSDIREALPLFYTELNFDGSFISLGDNKWGLRSWYGVDEIDEEIIALEENDDD
                     EVAPKAKKKRVNAFMDGDSDAIDYNADDPEDEDAYEADPALSYDDENPDDEKNEVEAY
                     DAEINEIAPDDLGEDVDLNEDDDEFSDDDAETSEE"
     gene            complement(4978..5427)
                     /locus_tag="VYO11_001288"
     CDS             complement(4978..5427)
                     /locus_tag="VYO11_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HEV1595855.1"
                     /translation="MCFVPYYKVNHCEEAFAWYQDVNLVYLVDGVKLPYSQATLEAMY
                     SYLDRHGELFWIEVKEKGEWFPIGDITLSQDNLPIVIGNSAYQHRGLGKKILSALIEL
                     ARVKGWKELRVKEIYTYNHASRRCFKSLGFVENGATEKGMSFILELV"
     gene            complement(5432..5821)
                     /locus_tag="VYO11_001289"
     CDS             complement(5432..5821)
                     /locus_tag="VYO11_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome partitioning protein ParB"
                     /protein_id="HEV1595856.1"
                     /translation="MKVNIADLHPTQLYLSEKKLQDIQMLYQSAETIQVDPISILAFG
                     DCLLITDGHHRAYQTLLADRDTISAEWDRDGGDELYHLYAQACEERKIYSVFDLEDRI
                     LAQDGYEAKWYNWCDGFNQAATLLLKR"
     gene            complement(5849..6475)
                     /locus_tag="VYO11_001290"
     CDS             complement(5849..6475)
                     /locus_tag="VYO11_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HEV1595857.1"
                     /translation="MKGSFALLLFVILGYMVKFYPETLVNFDQSIQTAIRGDLPDYLT
                     ILFRALTRLIDIPVIITWVVITAFVFYRKRWKIESFFMLGNLALAGLLIVTFKNIYQR
                     PRPDILHLVEEKGFSFPSGHSLAVTLMVGTLIVILSQRIKDPVWRKIVQIVLGLYLVS
                     VLVSRVYLGVHYPSDVLASLCVGLGVLFIEFPFYDKLRFQWRFKGKQK"
     gene            complement(6489..7052)
                     /locus_tag="VYO11_001291"
     CDS             complement(6489..7052)
                     /locus_tag="VYO11_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEV1595858.1"
                     /translation="MTNTRRLSTIAILSAISFVLMYFDFPLLPAASFLKIEFSILPVL
                     VGLVVMDLPAALGVLLLRSLLKLLLNSQGVNTYIGLPMNIVALGVFVIVFALIWKKER
                     TTLRFLLGSLAGTIGLTLAMLVLNYVYAVPLYAKFANFDIGKILGLSNYLMTMVLPFN
                     LIEGVIFSVSFWLLYVLLKPTLKHYER"
     regulatory      complement(7217..7451)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            complement(7505..8008)
                     /locus_tag="VYO11_001292"
     CDS             complement(7505..8008)
                     /locus_tag="VYO11_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (cytidine(34)-2'-O)-methyltransferase"
                     /protein_id="HEV1595859.1"
                     /translation="MTNHIVLFEPQIPQNTGNIARTCAATNSPLHIIKPMGFPIDDRK
                     MKRAGLDYWDKLEIYFYESLEDFISQMKGKLYLISKFAEKIYSEVDLSTDEDHYFLFG
                     REDKGLPEDFMREHPEKALRIPMNDEHVRSLNVSNTVCMIVYEALRQQNFAGLELVHT
                     YEVDKLK"
     gene            complement(8201..9031)
                     /locus_tag="VYO11_001293"
     CDS             complement(8201..9031)
                     /locus_tag="VYO11_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEV1595860.1"
                     /translation="MQAKLIGYQHRDTVIHRLSGAGKLLFFILVSLAAMISYDTRMLL
                     LIAIFSVFLLYLSEIRFKDVSFVAVFATVFAVLNVLMVYLFSPEYGVGLYGERSVIWQ
                     GIGVYTLTSQELFYLLNLAIKYLCTIPLAIIFLMTTHPSQFASSLNQIGVPYKIAYSV
                     SLTLRYIPDLQEEFFTIKMSQEARGMELSKKASLMQRIKGNLLIITPLIFSSLERIDT
                     IATAMELRRFGKEKKRTWYSYQALKKGDYITLLLATLFLVVSLLLILQNQGRFYNPWK
                     "
     gene            complement(9016..10698)
                     /locus_tag="VYO11_001294"
     CDS             complement(9016..10698)
                     /locus_tag="VYO11_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000656554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1595861.1"
                     /translation="MKEAIIEWKDFSFRYETQQEPTLQGIDLTIYKGEKVLIVGPSGS
                     GKSTLGQCLNGIIPNIYKGQTYGEFLIKGQVAFDMSIYDKSHLVSTVLQDTDGQFIGL
                     SVAEDLAFALENDVTALDEMKGRVYKWAEKLDLLPLLDQRPQDLSGGQKQRVSLAGVL
                     IDESPILLFDEPLANLDPKSGQDIIELIDQIHKEEGTTTLIIEHRLEDVLHRPVDRIV
                     LINDGRILFNGSPDQLLATDLLTQNGIREPLYLTTLRQLGVDLVKEEQLANLDNMSIS
                     KGQVQLQNELAKETPELQSLFKLEDVSFSYDDRPILKSLHLDIKKGEKIAIVGKNGAG
                     KSTLAKAISSFIQTEGRYLWEKQDIKGDSVAERAERVGYVLQNPNQMISTNMIFDEVA
                     LGLRLRGVDEKEIETRVYETLKICGLYEFRNWPISALSFGQKKRVTIASILVLGAEII
                     LLDEPTAGQDQKNYTEIMEFLEELHQKGHTIVMITHDMQLMLDYSDRVLVMVDGELIA
                     DTVPASLLSDPELLVKANLKETSIFNLAKKLDVDPLDLTAFYKERREGCKLN"
     gene            complement(10809..11057)
                     /locus_tag="VYO11_001295"
     CDS             complement(10809..11057)
                     /locus_tag="VYO11_001295"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1595862.1"
                     /translation="MKIKEQTRKLAAGCSKQCFEIVDRTDEVSSKHGFEVVDETDEVS
                     NHTYGKAKLTWFEEIFEEYKMMGKAGQLVFFDVYRLVR"
     gene            complement(11064..11612)
                     /locus_tag="VYO11_001296"
     CDS             complement(11064..11612)
                     /locus_tag="VYO11_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF-type riboflavin transporter
                     substrate-binding protein"
                     /protein_id="HEV1595863.1"
                     /translation="MEIKFTIKQVVAVGIGAALFVVIGMINIPTPVPNTSIQLQYAVQ
                     ALLSIIFGPIIGLLVGLIGHAIKDSLAGYGLWWTWIIASGLFGLVVGLFRKYVRVING
                     VFDWKDILIFNLIQLLANALVWGVLAPLGDVVIYQEAAEKVFAQGIVAGIANGVSVAI
                     AGTLLLLAYAGTQTRAGSLKKD"
     gene            complement(11627..12475)
                     /locus_tag="VYO11_001297"
     CDS             complement(11627..12475)
                     /locus_tag="VYO11_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-adenosyl-l-methionine hydroxide
                     adenosyltransferase family protein"
                     /protein_id="HEV1595864.1"
                     /translation="MNNNLLVLQSDFGLVDGAVSAMIGVALEESPTLKIHHLTHDITP
                     YNIFEGSYRLFQTVDYWPEGTTFVSVVDPGVGSKRKSVVAKTAKNQYIVTPDNGTLSF
                     IKKHVGIVAIREISEVANRRQNTEHSYTFHGRDVYAYTGAKLASSHITFEEVGPELSV
                     EQIVELPVVATIIEDHLVKGAIDILDVRFGSLWTSITREEFYKLEPEFGDRFEVTIYH
                     ADMLVYQNQVVYGKSFADVRIGQPILYINSLYRLGLAINQGSFAKAYNVGVGSSWTIE
                     IKKIEG"
     gene            12664..14013
                     /gene="trkA"
                     /locus_tag="VYO11_001298"
     CDS             12664..14013
                     /gene="trkA"
                     /locus_tag="VYO11_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk system potassium transporter TrkA"
                     /protein_id="HEV1595865.1"
                     /translation="MKIILVGGGKVGFALCRSLVAEKHDVLLIEQDEAVLNHIVSRFD
                     IIGILGNGADFAILEQASVQDCDIFIALTEHDEVNMIAAVLAKKMGAKETIVRVRNPE
                     YSNSYFKEKNILGFSLIVNPELLAARAIANIIDFPNALSVERFAGGRVSLMEFVVKST
                     SGLCQMPISDFRKKFGNVIVCAIERDHQIIIPSGDMTVQDKDRIFVTGNRVDMILFHN
                     YFKSRAVKSLLIVGAGRIAYYLLGILKDSRIDTKVIEINPEIASFFSEKFPNLYIVQG
                     DGTAKDILLEESAQHYDAVATLTGVDEENLITSMFLDRVGVQKNITKVNRTSLLEIIN
                     APDFSSIITPKSIAVDTIMHFIRGRVNAQYSDLQAMHHLANGQIETLQFHIKEANKMT
                     AKPLSQLKLKKGVLIAAIIRKGKTIFPTGEDMLEVGDKLLVTTLLPNITKIYDLIAR"
     gene            14017..15456
                     /locus_tag="VYO11_001299"
     CDS             14017..15456
                     /locus_tag="VYO11_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HEV1595866.1"
                     /translation="MNKSMIRYLLSKLLLIEAVLLLVPVAIAVYYRESSQVFTALFST
                     IGILVLLGGSGSLQKPKNQRIYAKEGVLIVALCWILWSFFGGLPFVFSGQIPSLIDAF
                     FEISSGFTTTGASILNDVSVLSRSLLFWRSFTHLIGGMGVLVFALAIMDNAKNSHLEV
                     MKAEVPGPVFGKVVSKLKNTAQILYLLYLALFSLFVIIYYLAGMPLYDSFVIAMGTAG
                     TGGFTVYNDGIAHYGSSLITYLVSIGVLVFGVNFNLYYYLMLRRIKAFFGDEELRAYL
                     VIVLVSTGLISLNTLYLYPGFSKSFEMTFFQVSNIITTTGFGYGDITNWPLFSQFILL
                     FLMAIGGSAGSTAGGLKIIRGLILSKIAKNQILSILSPHRVLTLHVNKTVIDKDTQHK
                     ILKYFVIYAMILLALIFIVSLDSNDFLVVTSAVFSCFNNIGPILGTTSSFSIFSPISK
                     ILLSFAMIAGRLEIYPILLLFMKRTWSKR"
     gene            complement(15582..16040)
                     /locus_tag="VYO11_001300"
     CDS             complement(15582..16040)
                     /locus_tag="VYO11_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS alpha-glucoside transporter subunit IIB"
                     /protein_id="HEV1595867.1"
                     /translation="MEVVLFSYCLNTRYLLQIVDIASSNDIILEEDTSEIMPGEIDVI
                     KSKELKVLVLCAGSGTSAQLANAINEGAQLAEVRVIANSGAYGAHYDIMGVYDLIILA
                     PQVRSYYREMKVDAERLGIQIVATRGMEYIHLTKSPSKSLQFVLEHYQAV"
     gene            16601..16771
                     /locus_tag="VYO11_001301"
     CDS             16601..16771
                     /locus_tag="VYO11_001301"
                     /inference="COORDINATES: protein motif:HMM:NF024172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV1595868.1"
                     /translation="MTKQVPKFTKDTAQLYTCKWLLYNKVTKMYDHTVVNHSVREYIT
                     DSISTNTIEKAG"
     gene            17383..17667
                     /locus_tag="VYO11_001302"
     CDS             17383..17667
                     /locus_tag="VYO11_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002923859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1595869.1"
                     /translation="MVWYDYMIQASKQSQFNASHWFRYLRKVIFEDYSYLTNQDVEKL
                     LDSKELTRFQKISLKYAFQEHTPTHKYVISLNKPAKLTNVQKLMEKYKHG"
     gene            17660..17908
                     /locus_tag="VYO11_001303"
     CDS             17660..17908
                     /locus_tag="VYO11_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1595870.1"
                     /translation="MDKMKPVFQALNKELIQENLTLTIICVDGYVLEYHGLRATQDVD
                     AFYDQNQKINEIIARVGKQFNLNIHEELWLNNHVAKQI"
     gene            18004..18222
                     /locus_tag="VYO11_001304"
     CDS             18004..18222
                     /locus_tag="VYO11_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1595871.1"
                     /translation="MMSIREQDLQDIGAIIKYKNFHSPFDTFKYLKDMGFDTIDLSVL
                     LEGFSYAYGMDWLEKFFKENQDKLREFY"
     gene            complement(18590..20914)
                     /gene="pflB"
                     /locus_tag="VYO11_001305"
     CDS             complement(18590..20914)
                     /gene="pflB"
                     /locus_tag="VYO11_001305"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HEV1595872.1"
                     /translation="MVVKTVVEAQDIFDKAWEGFKGVDWKEKASVSRFVQANYTPYDG
                     DESFLAGPTERSLHIKKIVEETKAHYEETRFPMDTRPTSIADIPAGFIDKENEVIFGI
                     QNDELFKLNFMPKGGIRMAETTLKENGYEPDPAVHEIFTKYVTTVNDGIFRAYTSNIR
                     RARHAHTVTGLPDAYSRGRIIGVYARLALYGADYLMQEKVNDWNAIKEIDEETIRLRE
                     EVNLQYQALQQVVRLGDLYGVDVRKPAMNVKEAIQWVNIAFMAVCRVINGAATSLGRV
                     PIVLDIFAERDLARGTFTESEIQEFVDDFVMKLRTVKFARTKAYDQLYSGDPTFITTS
                     MAGMGNDGRHRVTKMDYRFLNTLDNIGNSPEPNLTVLWTDKLPYNFRRYCMHMSHKHS
                     SIQYEGVTTMAKDGYGEMSCISCCVSPLDPENEEQRHNIQYFGARVNVLKALLTGLNG
                     GYDDVHKDYKVFDIEPIRDEVLEFESVKANFEKSLDWLTDTYVDALNIIHYMTDRYNY
                     EAVQMAFLPTKQRANMGFGICGFANTVDTLSAIKYATVKPIRDEDGYIYDYETIGDYP
                     RWGEDDPRSNELAEWLIEAYTTRLRSHKLYKDAEATVSLLTITSNVAYSKQTGNSPVH
                     KGVYLNEDGSVNLSKLEFFSPGANPSNKAKGGWLQNLNSLSSLDFSYAADGISLTTQV
                     SPRALGKTRDEQVDNLVTILDGYFENGGQHVNLNVMDLNDVYEKIMSGEDVIVRISGY
                     CVNTKYLTPEQKTELTQRVFHEVLSMDDALDALS"
     gene            21309..22370
                     /gene="dinB"
                     /locus_tag="VYO11_001306"
     CDS             21309..22370
                     /gene="dinB"
                     /locus_tag="VYO11_001306"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HEV1595873.1"
                     /translation="MLIFPLLNDLSRKIIHIDMDAFFAAVEIKDNPKLRGKPVIIGSD
                     PRQTGGRGVVSTCSYEARAFGVHSAMSSKEAYERCPQAVFISGNYEKYKAVGLQIRAI
                     FKRYTDLIEPMSIDEAYLDVTENKLGIKSAVKIARLIQKDIWQELHLTASAGISYNKF
                     LAKMASDYQKPHGLTVILPEQAEDFLKQMDISKFHGVGKKTVERLHQMGVFTGADLLE
                     VPEVTLIDRFGRLGYDLYRKARGIHNSPVKSNRIRKSIGKEKTYGKILRAEEDIKKEL
                     TLLSEKVALNLHQQEKAGKIVILKIRYEDFSTLTKRKSIAQKTQDASQISQIALQLYE
                     ELSEKERGVRLLGITMTGF"
     gene            complement(22517..23362)
                     /locus_tag="VYO11_001307"
     CDS             complement(22517..23362)
                     /locus_tag="VYO11_001307"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HEV1595874.1"
                     /translation="MYLIEILKSIFFGIVEGITEWLPISSTGHLILAEEFIQYQNQNE
                     AFMSMFNVVIQLGAILAVMVIYFNKLNPFKPTKDKQEVRKTWRLWLKVLIATLPLLGV
                     FKFDDWFDTHFHNMVSVALMLIIYGVAFIYLEKRNKARAIEPSVTELDKLPYTTAFYI
                     GLFQVLALLPGTSRSGATIVGGLLNGTSRSVVTEFTFYLGIPVMFGASALKIFKFVKA
                     GELLSFGQLFLLLVAMGVAFAVSMVAIRFLTSYVKKHDFTLFGKYRIVLGSVLLLYSF
                     VRLFV"
     gene            23683..24461
                     /locus_tag="VYO11_001308"
                     /pseudo
     CDS             23683..24461
                     /locus_tag="VYO11_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019779591.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         7418 a         5231 c         4560 g         7252 t
ORIGIN      
        1 ttacaaactt gacattaaca cttgttagat ttacttttat cctttaaaat agaataggag
       61 atattccgcg attatttttc ggaggaaaaa gaaatgtcca ttaattggca ggaaatttta
      121 tttcactttt taggtggtct ggggctattc ttatatagta tcaagaccat gggagacggt
      181 ttgcaacaag ctgctggaga tcgccttcgt ttttacattg acaaatatac tagtaatcct
      241 ttctttggag ttctggttgg tattgggatg actgctctaa ttcagtctag ttctggtgta
      301 acagttatta cagtcggcct ggtcagtgcc ggtctcttaa ccttacgtca ggctatcggg
      361 attgtcatgg gtgctaatat tgggacaact gtcacatcct ttctcatcgg ttttaaatta
      421 ggtaactatg ccctacctat gctctttatc ggtgccgtct gtctcttttt tacgaaaaat
      481 cggacagtca ataatatcgg acgcatcctc tttggtgtcg gtggtatctt ttttgccctc
      541 aatctcatga gcggcgcaat ggctccactc aaggatttac aggtctttaa ggactatatg
      601 attgagctaa gtaagaatcc cgttttgggt gtctttgtcg gtactggctt gaccttgcta
      661 attcaagctt cttcggctac cattgggatt ttacaaaacc tctacgccgg caatctaatt
      721 gacctacagg gagctttgcc agttctattt ggtgacaata tcgggacaac cattacagcc
      781 atcattgcct ctttaggggc taatattgca gctaaacggg tagcaggagc tcatgttgcc
      841 ttcaacgtta tcggaacagt cgtctgcgtt atttttctag ttccttttac tgtcctgatt
      901 cattggtttg aagctacgct aaatctagca ccggaaatga ccatcgcctt tgctcacgga
      961 acctttaata ttaccaacac cattgtccaa tttccattta tcggagctct ggcttacttt
     1021 gtaaccaaga ttattcctgg agaggacgag gttgtcaaat acgaaccctt atatcttgat
     1081 gaacatttca tcaaacaggc cccatctatc gctctaggaa atgctaagaa agagctcttg
     1141 cacttaggaa actacgctgc taaagccttt gacctttcct ataagtacat cattgacttg
     1201 gatgaaaaag ttgctgaaaa agggcataaa accgaagaag caattaacac catcgatgag
     1261 caattaacac gttatctcat tgccctttca agcgaagctc tcagccaaaa agaaagtgaa
     1321 gtgcttacca atatccttga ttcctcccgt gatttggaac ggattggaga ccacacggag
     1381 gctctactca atctgactga ctatcttcaa cggaaaaatg ttgaattttc tgatgccgcc
     1441 ttgaaagaat tagaggaagt ttaccgccaa actagtgact ttatcaaaga tgctctggat
     1501 agtgtggaaa acaatgatat tgaaaaagca cgcagtcttg tagaacgtca tgaagcaatc
     1561 aataagatag aacgtgttct cagaaaaacc cacatcaaac gcctcaacaa aggcgaatgt
     1621 tcaacacaag ctggggtcaa ctttatcgac atcatctcac actacactcg tgtatcagac
     1681 cacgctatga accttgctga aaaggttttt gcagaacaaa tctaataacc aagaagctat
     1741 ccatcataat tggatggctt cttacttttt cctaagcaag actaggctga atgaaactga
     1801 aagagtattc tgcagatata tagtatattg aaactagaat agtacacctc tatttctaaa
     1861 acattgttag aaatcgattt gtcctgttat tatttcattt tactataatg gattaaatta
     1921 aaaaagtata gtgtattgaa tctataacag tacaccttga ctgctaaaat atttctataa
     1981 attaatttga cttttctgat agagatgttc acatcttatt tcaattcatg atacaatcca
     2041 gttcctaaaa ctttgctaga aattaatttg gctttccgaa ttaatttgtt caaattttat
     2101 ttcatttcaa tatactgata aatccattca ctagcacagg gcaagaggga gtcgctattg
     2161 atttcaacgg tagcaggtac atacagagga ctcctacctc agatatactg caatatcatc
     2221 gtatgcaaaa aacctctgag atttttctca aaggttctga ttttgctaat tgctgttctc
     2281 aaccgctgca gtaacaaagg cagtgtagag ttcttctggt cggtttggac ggcttgacag
     2341 ttcaggatga tactgacaag ctacaaagaa tttattttca ggaatttcca cgatttctac
     2401 caaacgattg tctggagaaa ctcctgaaaa gacaaaacct gctgcctcaa actgctcacg
     2461 gaaggcatta ttaaactcat aacggtgacg gtgacggcgt tgcaccactt cttgattgtg
     2521 ataagcagca gcagccttag agccacgttt caacttagac ggataaagtc ccaaacgaag
     2581 ggttccaccc atatcctcaa tatcaatctg atcacgcatg atatcaatga tagggtattt
     2641 tgtttctggt gcaagctctg cagaattggc accttcaaga cctaaaacgt gacgagcaaa
     2701 ctcgatacat gtcaactgca ttcccaagca gactcccaac attggaacat cattttcacg
     2761 cgcatagcgg atggcttgga ttttcccttc tgtaccacgt tgaccaaaac cacctggtac
     2821 gatgatcccg tccgcatcag acaagagttc tgctacattc tctgctgtca catcattggc
     2881 attgacccaa ttgattttaa cttctacatc attgacatag ccagagtgtt tcaaggcttc
     2941 gaccactgag atataggcat cttgcaactc cacatactta ccaacaaggg aaatcttaac
     3001 ttgtttcttg aggttcatga ccttgtccac catggctgac cattctgtca tatccgctgc
     3061 tggtgcgtct aatttcaaat gatcacaaac aatttggtcc atcccttgtg cctgcaagtt
     3121 cagtggaatt tggtaaaggt gttcaacatc caacgattcg ataacggctt ctggtgccac
     3181 atcacagaac tgggccagtt tatttttaat tccttgacca gctggctctt ctgtacgaat
     3241 aaccaacata tttggttgga ttcccaagcc acgcaattct ttgacagagt gttgggttgg
     3301 tttggttttc atttcaccag cagccttgag gtaaggaagc aaggttgtat ggatatacat
     3361 gacattatcc gcacccacat ctgccttcat ctgacgaaga gcctctagga atggcaagga
     3421 ctcgatatct cctactgttc caccaacctc tgtgataatg acatcagagt cggtcgttag
     3481 agcggcacgc ttgatttttt ctttcaaagc atctgtgata tgaggaatga cttgaacagt
     3541 tgccccaagg tattctccac ggcgttcttt acgaagaact tcactgtaaa ttttcccagt
     3601 tgtcacgttg gaatatttgt tgagattgat atcgatgaaa cgttcatagt gacccaagtc
     3661 caaatctgtc tcagctccgt catctgtcac aaaaacttcc ccgtgctggt aaggactcat
     3721 ggttcccgga tcaatattga tataagggtc aaacttttga atggttactt tgagaccacg
     3781 atttttcaag agacggccta gactcgctgc cacaatccct ttcccaatag acgataccac
     3841 accaccagtt acaaaaatat atttcgtaga catagattcc tctttctaaa atgctcaagg
     3901 tcttgttaac tacgagggga tatagaaaac aagaccctac taataagaat aatctgggac
     3961 gactgcacca gattcacagc taatactctt cgaaaatctc ttcaaaccgc gtcaacgtcg
     4021 ccttgccgta gatatgtgtt cctgactttg tcagtcttat ctacaacctc aaaatagtgt
     4081 tttgagcagc ctacggctag tttcctagct tgctctttga ttttcattga gtataaaata
     4141 caagaagata acttcttgaa aaaacaaaaa tagctcccta agaactaggg agccccgacc
     4201 tctaaaagag gtgcccaaac aatatgatac ctaaaaatag gataattgtc aatagctaac
     4261 tcttattcct cgctggtttc agcgtcgtca tctgaaaact cgtcgtcgtc ttcgttgaga
     4321 tccacatctt ctcccaagtc atctggagcg atttcgttga tttctgcatc ataagcttcc
     4381 acttcatttt tttcatcatc tggattttca tcatcgtatg aaagagctgg atctgcttcg
     4441 tatgcatctt cgtcttctgg atcatctgca ttgtagtcaa tggcatctga atcaccatcc
     4501 ataaaggcat tgacacgttt tttcttagct tttggtgcta cttcatcgtc gtcattttct
     4561 tcaagagcga tgatttcttc gtcgatttcg tccacaccat accatgaacg aagaccccat
     4621 ttgttgtccc caagtgagat gaagctaccg tcaaagttca actctgtgta gaacaaaggc
     4681 aaagcttcgc ggatatcgct gtttgatgtt ccaaggtagt tttgaatttc gtttacaaga
     4741 tcgctaaaat gcatctcatg atcgcgacca cgaagttcca agatagcacg cgctacctca
     4801 atcatagata gttcactttt ttcttgccca gcaaatactt ctaattccaa agcgtttctc
     4861 ctcatttata ctactatcgc cagagcgaac agactctgac ctcattttat catttactct
     4921 ttattttacg ataattttgc agaatagtca aaggttaagg gggagaaaat ggcaggatta
     4981 gactaattcc aatataaaac tcattccttt ttctgttgct ccattttcca caaatccaag
     5041 cgacttgaaa cacctcctag aagcatgatt gtaggtgtag atttccttga ctctcaattc
     5101 tttccatcct tttactcgag ccaattcaat caaagcactt agaatctttt ttccaagtcc
     5161 tcgatgttgg taagcggaat tcccaatcac aatggggaga ttatcctgag atagtgtaat
     5221 atccccaatt ggaaaccatt ctcccttctc cttgacttca atccaaaaaa gctcaccatg
     5281 ccgatccaaa taggaataca tggcttccaa ggtcgcttga ctgtaaggaa gcttcacccc
     5341 atctacgagg taaaccaagt tcacatcctg ataccaagca aaagcttcct cacaatgatt
     5401 gaccttataa taaggaacaa aacacaatgc actacctttt caacaaaaga gttgctgctt
     5461 gattaaaacc atcacaccag ttataccatt ttgcttcata cccatcttga gctaggatac
     5521 gatcttctaa atcaaaaaca gagtaaatct ttctttcctc gcaagcttgc gcatagagat
     5581 gatatagttc atcaccacca tctctatccc actcagcaga aatcgtatcc cgatctgcca
     5641 ataaagtctg ataagccctg tgatgcccat ctgtaatcag caaacaatct ccaaaggcaa
     5701 gaatactgat tggatcgact tggattgttt ctgccgactg gtaaagcatc tgaatatctt
     5761 gcaacttctt ttctgataaa tatagttgag tcggatgaag atctgctatg ttgactttca
     5821 tttctttctc ctcaagggaa ttcgatactc acttctgttt gcctttaaat cgccattgga
     5881 agcggagctt gtcatagaag ggaaactcga taaacaggac tcccaagccc acacagagac
     5941 tggcaaggac gtctgatggg taatgaactc ccagatagac tcttgatacc agcacactga
     6001 ctaggtagag gccaaggacg atttgtacga tttttctcca gactggatct ttaatccgct
     6061 gactaagaat aacaatcaaa gtacctacca tcaaggttac agccagagaa tgcccacttg
     6121 ggaaggaaaa tcccttctcc tccaccagat gtaagatatc tggccgtggg cgctggtaga
     6181 tatttttaaa ggtcacgatt aaaagacctg ccaaagccag atttcccagc atgaagaaac
     6241 tttctatctt ccatcgctta cgataaaaga caaaagctgt aatgacaacc caagtgataa
     6301 tcactgggat atcaatcaga cgtgtgaggg ctcgaaaaag aatagtcaaa taatctggta
     6361 agtctcctcg aatggcagtc tgaatcgatt ggtcaaaatt gaccagcgtt tcagggtaaa
     6421 atttgaccat gtagccaaga ataacgaaaa gtaaaagggc aaaactgccc ttcattaaaa
     6481 atgtttgttt atctctcata atgttttaag gttggtttca agagaacata caacaaccag
     6541 aatgaaacgg aaaagataac accttcaatc aagttaaaag gtaataccat ggtcattagg
     6601 tagttggaaa gtcccaaaat ttttccaata tcaaagttag caaacttagc gtacaaagga
     6661 acagcataaa catagttgag aaccaacatg gccaaggtta aaccaatagt tccagctaga
     6721 gagcctagta ggaaacgaag ggttgtccgt tcctttttcc aaatcaaagc aaatacgatg
     6781 acaaaaactc ccaaagctac gatattcatc ggcaaaccaa tgtaagtatt cactccttgg
     6841 ctgttaagaa gcaacttcaa gagtgagcga agcaagagca ctcctagagc agcaggcaaa
     6901 tccatgacca ccagacccac aaggactggc aagatactaa attcgatctt gaggaaagat
     6961 gccgctggta aaagcggaaa atcaaagtac atcagcacaa atgagatggc tgatagaatt
     7021 gcaatggtcg aaagtcgacg tgtgtttgtc ataacaggtt cctccaattt tctataaaat
     7081 cagaagaagt tggaaaggat tcctctatct attctcactt tttatatccc aaaagttccc
     7141 tcttactcta ttaaagaaaa acaaagcaag tggttacaat ccggctataa atctatcaaa
     7201 acagacaaag ctattctttc gtcttctccc atccagacta tactgtcggt tgtggaatct
     7261 caccacatca gcttgcgctc gcggacttct ttaaagagaa agaaatagag atttttcttt
     7321 tagactaggc gacaagctgt aggcataact tctggttagg caaagcttgt caacaaagta
     7381 taaaaggaaa agatcatttc ctagttaaag tcaccgccgg tcgggaatca caccctgccc
     7441 tgaagactct tttatcataa caaaaaacgc ttgcaagcgc aagcattttg ttcattttca
     7501 ttttttattt caatttatcc acttcatagg tatggacgag ctcaagacct gcaaagttct
     7561 gctggcgaag agcctcatag acaatcatgc agacggtatt agacacattg agactgcgga
     7621 catgttcatc attcatggga atacggagag ccttctcagg atgttctcgc ataaaatctt
     7681 caggtaagcc cttgtcttca cgtccaaaga gaaaataatg gtcctcgtca gtcgataaat
     7741 ccacctcaga atagattttt tccgcgaatt tcgaaatcag atagagtttt cccttcatct
     7801 gagatatgaa atcttctaaa ctctcgtaaa aataaatctc tagcttatcc cagtaatcca
     7861 atccagcccg cttcatcttg cggtcatcaa taggaaagcc cataggcttg atgatgtgga
     7921 ggggagaatt ggtcgcagcg caagtacgcg cgatattgcc tgtattttgt ggaatttgag
     7981 gttcaaataa tacaatgtga tttgtcatga cttgcttcct ttcaccattg caaaaaaata
     8041 gccacactgc ccggagtcaa gctcagcaaa cagcgtggtt aaggcatcgt taacttacct
     8101 cacaacaggt ttgaagtaaa tcagcgaaac tactttctta gtataacact ttcagaatca
     8161 ttgtcaatag aaatgacttg attttttcaa ttttttcaag ctatttccaa gggttgtaaa
     8221 atcgtccctg attctgcaag ataagtagta aactaactac taaaaacaag gttgccaaga
     8281 gcaaggtaat atagtctcct tttttcaagg cctgataact ataccatgtg cgttttttct
     8341 ctttcccaaa gcggcgaagc tccatggcag tcgcaatggt atcaatgcgt tctagcgagc
     8401 taaaaatcaa gggcgtaata atgagcagat tgcctttgat tcgttgcata agagaagctt
     8461 tcttggataa ttccatccca cgcgcctcct gagacatctt gatagtaaag aattcttcct
     8521 gcaaatctgg aatatagcgc aaggtcaggc tgacagaata agcaatctta tagggcacac
     8581 caatttgatt taaactggaa gcaaactgac taggatgggt tgtcatcaaa aagataatag
     8641 ccagaggaat ggtgcaaaga tacttaatgg ccaaatttag cagataaaag agctcctggc
     8701 tggttagagt gtagacaccg attccctgcc aaatcacact tctctctcca taaagtccaa
     8761 ccccatactc gggagaaaag agatagacca tcaaaacgtt taaaacggca aataccgtcg
     8821 caaaaacggc tacaaaggaa acatctttaa agcgaatttc tgataaatag aggagaaaga
     8881 ctgaaaagat ggcaatcagc aagagcattc tggtatcata gctaatcatg gccgccaatg
     8941 ataccagaat gaaaaagaga agtttcccag ctcctgacaa gcgatgaatc acagtatctc
     9001 tatgctggta accgattaat ttagcttgca tccctctctc ctttctttgt aaaatgccgt
     9061 taaatccagt ggatccacat ctagtttctt agccaagtta aagatggagg tttcttttag
     9121 attggctttt actaacagct caggatcgct caacagactg gctggaacag tatcggcaat
     9181 caattctcca tccaccatga caaggacccg gtctgaataa tccagcatca attgcatatc
     9241 atgggtaatc atgacaatgg tatgcccttt ttgatgtaac tcttcgagaa attccataat
     9301 ctcagtatag ttcttctgat cttgacctgc agtcggttca tctaggagaa taatttcagc
     9361 tcctaagacc aaaattgaag caatggtgac acgttttttc tgaccaaatg acagggcaga
     9421 aataggccaa ttacggaatt cataaagtcc acagattttc aaggtttcat agactctcgt
     9481 ttcaatttcc ttctcatcca cacctcgcaa acggagccct agagccacct catcaaaaat
     9541 catattggtt gaaatcattt gattaggatt ttgtagcaca tagcctactc gttccgcccg
     9601 ctctgcaaca gaatcgcctt ttatatcctg tttttcccaa agatagcgtc cttccgtctg
     9661 aataaagcta cttatagcct tggctagagt tgatttccct gctccatttt ttccgacaat
     9721 agcaatcttt tcaccctttt taatatctaa atgtagggat tttaaaatcg gtctatcatc
     9781 ataagagaaa gacacgtcct ctaatttaaa gagtgactgc aattctggag tttcttttgc
     9841 cagttcattc tgcagctgaa cctgaccttt tgagatagac atgttatcca gattcgctaa
     9901 ctgttcttcc ttgactaagt ccacacctaa ttgacggaga gtcgttagat aaaggggttc
     9961 tcgaattcca ttttgagtca ataaatcagt cgcaagcaac tggtcagggc tcccattaaa
    10021 aaggatacga ccatcgttta tcaagacaat ccgatccaca gggcgatgca gaacatcctc
    10081 caaacggtgc tcgataatca gagtcgtcgt cccctcttcc ttatgaatct ggtcaatcaa
    10141 ttcgataata tcctgacctg acttgggatc tagattggcg agtggctcat caaacaagag
    10201 aatcggactt tcatcaatca agacaccagc cagactgact cgctgctttt gtccacctga
    10261 caaatcctga ggacgctgat ccagtaaagg aagaaggtcc agcttttcag cccatttata
    10321 aacacgacct ttcatctcat ctagggctgt cacatcattt tccagagcaa acgccaaatc
    10381 ttctgccaca gacaagccaa taaactgccc atctgtatcc tgcaaaactg tgctaaccag
    10441 atgagactta tcatagatgc tcatatcaaa ggctacttga ccctttatca aaaattctcc
    10501 atatgtctga cccttgtaaa tattgggaat aatcccattc aaacactgac ccaaggtaga
    10561 tttacctgac ccagatggtc caacaattaa gactttctct cccttgtaaa tggtcaagtc
    10621 tatcccttgc aaggtcggtt cttgttgtgt ttcataccgg aaagagaaat ccttccactc
    10681 aattatagct tctttcatct tactctcttc attcgcttct tagacttcta ttttatcata
    10741 aatcaagccc ttcttgcagt ctctcctctt aaaatcttag cgccaaaaag attcctatcc
    10801 tagcttactt acctaactaa tctataaaca tcgaaaaaga ctagttgccc agccttcccc
    10861 atcattttat actcttcgaa aatctcttca aaccacgtca gcttcgcctt gccgtaggta
    10921 tggttactga cttcgtcagt ttcatctaca acctcaaaac catgttttga gctgacttcg
    10981 tcagttctat ccacaatctc aaaacactgt tttgagcaac ctgcggctag cttcctagtt
    11041 tgctctttga ttttcattga gtattagtcc tttttcaaac ttcctgcacg agtttgggtt
    11101 cctgcatagg caagtaagag aagagttcct gcaatagcta cagatacacc attggcaatt
    11161 cccgcaacaa tcccttgtgc aaatactttt tctgccgctt cttgataaat cacaacatct
    11221 ccaagtggtg ccaagacacc ccaaacaagg gcatttgcaa gtagttgaat gaggttaaaa
    11281 ataagaatat ctttccagtc aaaaacacca ttgatcactc gaacgtactt tctaaaaagt
    11341 cccacaacta gaccaaagag tccgctagcg ataatccaag tccaccatag accataacca
    11401 gcaagagagt ccttgattgc atgaccaatc aacccgacaa gcaaaccgat aatcggtcca
    11461 aaaataatag aaagtagcgc ttgtaccgca tactgaagct ggatgcttgt atttggaaca
    11521 ggggttggaa tgttgatcat cccgatgacg acaaagaggg cagcgccaat tccgacagca
    11581 acaacttgtt taattgtaaa tttgatttcc atactattct cctattttat ccttctattt
    11641 tctttatttc aatggtccaa gatgaaccga cacctacatt ataggccttg gcaaaggaac
    11701 cttggttgat agccaaacct aaacgataga gagagttgat gtaaaggatg ggttgcccaa
    11761 ttctcacatc tgcaaatgat ttgccataga caacctgatt ttgatagacc agcatatcag
    11821 catgatagat ggtcacttca aaacgatcac caaattctgg ttccagcttg taaaattctt
    11881 cccgtgtgat agaggtccaa agcgaaccga aacgcacatc cagaatatca atggctccct
    11941 tcaccagatg atcttctatg atggtcgcta cgactggaag ctctacaatc tgttccacac
    12001 tgagctctgg ccctacttcc tcaaaagtaa tgtgactact ggccagttta gcaccagtat
    12061 aggcatagac atcacgaccg tggaaggtat aagaatgctc tgtgttttga cgcctattgg
    12121 ccacctcaga aatctcacga atggctacaa tgccaacgtg tttcttgata aaggaaagcg
    12181 tcccattatc tggcgtgaca atgtattgat tttttgcagt cttggcaact acactcttac
    12241 gtttcgaacc gacacctgga tcgacaaccg atacaaacgt cgttccctca ggccagtaat
    12301 ccaccgtctg aaagagacga tagctcccct caaaaatatt ataaggcgtg atatcgtgcg
    12361 tcaagtgatg gatttttaag gttggagact cttctaaagc cactccaatc atagccgata
    12421 ccgcaccatc aaccagacca aagtctgatt gtaataccag taaattatta ttcattttat
    12481 ctccttgtat atcctttatc ataccatatt tcagagaaag tcgctaatag ctatttcaat
    12541 tggttagggt atagttttac cttatagcaa atttcctact aaaagttctt gttattagct
    12601 agtaggtgca ttttttcttg aaaaagggta tgatagttac atcatgaaaa agtaggtttt
    12661 attatgaaaa ttatccttgt cggaggggga aaagttggtt ttgccctctg tcgctccttg
    12721 gttgcagaaa agcatgatgt tttgctgatt gagcaagacg aagctgttct caatcatatt
    12781 gtcagtcgct ttgatatcat tggtatcctt ggtaatgggg ccgattttgc cattcttgag
    12841 caagccagcg tccaagattg tgatatcttt atcgccctga ctgagcacga tgaagtcaac
    12901 atgattgcag cagttctagc caagaaaatg ggagctaaag aaactatcgt tcgggtgcgg
    12961 aaccctgaat attctaactc ttatttcaag gaaaagaata ttctcggttt ttctcttatc
    13021 gttaatcctg agctcttggc tgcccgcgct atcgcgaata tcattgactt ccccaacgcc
    13081 ctgtctgtcg aacgctttgc tggtggacgc gttagcctca tggaatttgt cgtcaagtcc
    13141 accagcggtc tttgccaaat gcccatttct gattttcgta aaaaatttgg taatgtcatt
    13201 gtctgtgcga tagagaggga tcatcaaatt atcattccaa gcggtgacat gactgtacag
    13261 gataaagata gaatctttgt cactggtaac cgtgtcgata tgatactctt ccataattat
    13321 tttaaatcac gcgccgtgaa gagccttctc atcgttgggg caggtagaat tgcctattat
    13381 ctacttggta ttctcaaaga tagtcgtatc gatacaaaag tcattgaaat caatcctgaa
    13441 atcgccagct tctttagcga gaaattccca aatctctaca tcgttcaagg agatggaacc
    13501 gcaaaagata tcctgctgga agaaagtgct caacactatg atgccgttgc gactctaaca
    13561 ggtgtcgatg aggaaaatct gattacatct atgttccttg acagggtagg tgtacagaaa
    13621 aatattacta aggtcaatcg taccagtctc ctcgagatta tcaatgcgcc tgatttttca
    13681 agtatcatca cacctaaaag catcgctgta gatacgatta tgcactttat tcgtggtcga
    13741 gttaatgccc agtattcaga ccttcaagcc atgcaccatc tagccaatgg ccaaattgaa
    13801 accctgcaat tccatatcaa ggaagccaat aaaatgactg ccaaacctct ttctcaactg
    13861 aaattgaaaa aaggggttct tattgcagcc attattcgaa agggcaagac tattttccca
    13921 actggggagg atatgttgga agttggagac aagctcctag taacaacctt gttgccaaac
    13981 atcaccaaga tttatgactt gattgcgagg taagaaatga ataaaagtat gattcgttac
    14041 ctcctttcaa agttactttt gattgaagct gttctcctct tggttcctgt ggctatcgct
    14101 gtctattacc gtgaatcgag ccaagtcttt acagccctct tttcgaccat agggattctc
    14161 gtattgttag gcggttcagg gagtttacag aagccaaaaa atcaacggat ttatgccaag
    14221 gagggagtct tgatcgttgc cctctgttgg atcctttggt ctttctttgg tggtctcccc
    14281 tttgtctttt ctgggcaaat ccccagcctt attgatgcct tttttgagat tagttccggc
    14341 tttacgacta ctggagcaag tattttgaac gacgtttcag ttctcagtcg ttccctcctc
    14401 ttctggcgaa gttttaccca cttgattgga gggatgggag tgcttgtttt tgcacttgct
    14461 attatggaca atgccaaaaa tagccaccta gaggtgatga aggctgaggt tccaggtcct
    14521 gtttttggca aggttgtatc caaactaaaa aacactgccc agattctcta tctcctttat
    14581 ctagctctct tctccctctt tgtcatcatc tattatctag ctggtatgcc tctctacgat
    14641 agttttgtca ttgctatggg gacagcggga actggaggct ttaccgtcta taacgacgga
    14701 attgcccact atggcagctc actgattacc tatctggtca gtatcggagt tctggttttt
    14761 ggagtaaatt tcaacctcta ctactacctc atgctccgtc gcatcaaggc cttctttgga
    14821 gatgaagagc ttagggctta cttggtcatt gtactggttt ctacaggctt gattagcctc
    14881 aacaccctct acctctaccc agggttttca aagagctttg aaatgacctt cttccaggtt
    14941 tccaacatca ttacaacaac tggttttgga tatggagata ttaccaactg gcccctcttc
    15001 tcccagttta tcctcctttt cctcatggca atcggtggct ctgctggatc aactgcaggt
    15061 ggactcaaga ttattcgagg cctcatcctt tcaaaaattg ccaaaaacca aattttgtca
    15121 atcctatcgc cccaccgtgt tttgaccctc catgttaata aaacggtgat tgacaaagat
    15181 acccagcata agattctcaa gtactttgtc atctatgcta tgattttgct agcgcttatc
    15241 tttattgtca gcctagatag caatgatttt ctggtcgtga ccagcgctgt ctttagctgt
    15301 ttcaataata tcgggcctat tctaggaacc acttctagtt tctcaatctt tagtcccatc
    15361 tcaaaaattc tcctatcctt tgcaatgatt gcagggcgct tggagattta cccaatcctc
    15421 cttctcttta tgaagagaac ttggtctaag agataaaata caaaatccct ctttttacaa
    15481 ttgtgaaaga gggattctta tattaaaaaa gggggaacgt ttttaaatcc aagcctatct
    15541 gtaagcaaaa tccttactca aataaaagat ggaaaaactt actacacagc ttggtaatgc
    15601 tccaatacaa attgtaagga tttacttgga ctctttgtta aatgaatata ttccattcct
    15661 ctggtagcaa ctatctgaat acctaatctt tctgcatcca ccttcatctc tctataataa
    15721 ctccgaactt gtggagccag aataattaaa tcataaacac ccataatatc ataatgagct
    15781 ccgtacgctc ctgaattcgc aatcactcta acttctgcta attgagcgcc ctcgttaatt
    15841 gcattggcta attgcgcact tgttccagac cctgcacaaa gaaccagtac tttcaactcc
    15901 ttacttttta ttacatctat ctcaccaggc attatttcac ttgtatcctc ctctaaaata
    15961 atatcatttg agcttgcaat atctacaatc tgtagtaaat atctcgtatt tagacaatat
    16021 gaaaacaaga cgacttccat ataggaaacc gccttctcgc tatgttgagt gatttatatt
    16081 aaaataactt ttcttctagc tgcattttat tattataaaa acattcatca taacccccag
    16141 aacttaaata acaattttta ttcaagatac atactcctag aataaacttt atatgaaatt
    16201 ctcatttttg tttttacaat tctccttagt taaatcttgt ttaatatatg ttttacatat
    16261 agtatttagc gccacatagt actgaactct ctccaaaaac ggttatgcct ctttgaatag
    16321 ggcgttatca caagaaaagc atctccacgt ttcaacttca tatggctcaa aaacaatcaa
    16381 ttgatgctaa aacctgtacc tagatgtttc ggttcataaa accatgaaac tgtaaaagtg
    16441 gatgaaattg atagcgatag tcaaatcaag aggcatcata actctaaaaa gtcacaatat
    16501 ataagttcat cctcggaaaa atatcattct aattgttgaa atgcctacat gaaaagaaac
    16561 gtcaaatact catgaaacaa cgaatacagg tatcaaaact atgacaaaac aagtccctaa
    16621 atttactaaa gacactgctc aactttacac ctgtaaatgg ttgttgtata ataaagttac
    16681 aaagatgtac gaccacactg ttgtaaatca tagtgttcgc gaatatatta ctgatagcat
    16741 ttctacaaat acaattgaaa aggctggata ggctttaaac gaaatatgtc agtgttttgg
    16801 cattcctagc cttcatatca tttaaagaat tgtatagaca aaatttttcc caatacagac
    16861 actcgtaaca actgcttcat ttttctacca acatatttag gaacaggata agatacaaga
    16921 ggattaatcc atagatcagt tctataccaa tctaagacaa ataagctaaa aaaacgattg
    16981 ataataagca aatagattcc aaattttctc tatctgctca ttttaataaa caatactagt
    17041 gtaactatcc ttccagtcag aagcttgtca aatcacaccg aaaattcttc taaaatttat
    17101 ctcgttaggc aatcaagcaa aaactcgacg atagtacaaa cattatcata cagaattgac
    17161 ttcctaaatt atatacttta gtaaggtttt cggataagaa aaaaggttca ttttacattt
    17221 ctaaacattc ttttctaaga tgaaaaacag aatttttcga ttgtgattta aagcaacaag
    17281 aagattttca gtatcatcct atagatacga gctaattaag aaaaactaca tttttgaata
    17341 taaactacaa taatataaac taaattttat aggaggaaga caatggtttg gtacgattat
    17401 atgatacagg catccaaaca atcacaattc aacgcaagcc attggtttcg ctatttgcga
    17461 aaagttattt ttgaagacta ttcttattta acaaaccaag atgtagaaaa gttgctagac
    17521 tccaaagaac taacccgttt tcaaaaaatt agcttgaagt atgcctttca agagcatact
    17581 ccaactcata aatatgtgat ttcattaaat aaacctgcta agttaaccaa tgttcaaaaa
    17641 ttgatggaga aatacaaaca tggataaaat gaaaccggtc ttccaagccc taaataagga
    17701 attaattcag gaaaatctga ctttaacaat tatctgtgtc gatggttatg tcttagaata
    17761 tcatggttta cgtgccacac aagatgttga tgctttttat gaccaaaatc agaaaatcaa
    17821 tgaaattatt gctcgtgtag gaaaacagtt taatcttaac atccacgaag agttatggct
    17881 caacaatcat gttgcaaagc aaatatgaac aaacaacctc ccttaagttt atgcgaatcc
    17941 ttgtactcat ttgagaatct gaccgtttta gtagtcccta ttgagtatgt gttaggaatg
    18001 aagatgatga gtatcagaga gcaggatttg caagatattg gtgcaattat taaatacaaa
    18061 aactttcatt caccattcga tacctttaaa tatttaaaag acatgggatt tgatactatt
    18121 gacctctctg ttctattaga aggttttagt tatgcttatg gtatggattg gttagaaaaa
    18181 ttttttaaag aaaatcaaga taaacttcgc gaattttatt aacagtatca aacaagatga
    18241 ttgtcaatta gccagtcgtc ttgtttttta tgatgaaatg aaataaaatc tgaacaaatc
    18301 gcttagagaa ttccagtcaa tttctagcgc tgtttgagac gtttcagtgg actatagtaa
    18361 aatgaaataa gaataggaca aatcgatcag gacagtcaaa tcgatttcta agaatgtttt
    18421 agaaataaag gtgtactatt ctagtttcaa tctattatat ttcagattcg gtccactatt
    18481 ccttcccaaa aacattgcat attgcgccga aggaattgct cacactatcc caagcacaaa
    18541 accctcagtc gtttgaccga gggttccttt tcattattca agaacttgat tagctcaatg
    18601 catccaaggc gtcatccatt gaaagaactt cgtggaagac acgttgtgtc aattcagttt
    18661 tttgttctgg agtgaggtat ttagtgttta cacagtatcc agagatacgt acgataacgt
    18721 cttcgcctga catgatcttt tcgtaaacat cgttcaagtc cataacgttc aagttaacgt
    18781 gttgtccacc gttttcgaag taaccatcaa ggattgttac caagttatca acttgttcat
    18841 cacgagtctt accaagagcg cgaggtgata cttgtgtagt caatgagata ccgtcagctg
    18901 cataactaaa gtcaaggcta gaaagtgagt tcaagttttg caaccaacca cctttagctt
    18961 tgttagatgg gttagcacct ggtgagaaga attcaagttt agacaagttc acagaaccat
    19021 cttcgttgag gtatacacct ttgtgaactg gtgagttacc agtttgttta gagtaagcaa
    19081 cgttagatgt gattgtcaaa agtgatactg tagcttctgc gtctttgtat agtttgtggc
    19141 tacgtagacg agttgtgtag gcttcgatca accattctgc caattcgttt gaacgtgggt
    19201 catcttcacc ccagcgtggg tagtcaccga ttgtttcgta atcgtagatg tagccatctt
    19261 cgtcacggat tggtttaact gtagcgtatt tgatagctga caatgtatca acagtgttag
    19321 caaatccaca gataccgaat cccatgttgg cacgttgttt agttggcaag aaggccattt
    19381 gaacagcttc gtagttgtac ctatcagtca tgtagtggat gatgttcaag gcatctacgt
    19441 aagtgtcagt caaccagtca agagattttt caaagttcgc tttaactgat tcgaattcaa
    19501 gaacttcgtc acggattggt tcgatatcaa atactttgta gtctttgtga acatcgtcgt
    19561 aaccaccatt caaaccagta agaagggctt taagaacgtt tacacgagca ccgaagtact
    19621 ggatgttgtg gcgttgttct tcattttctg gatcaagtgg agacacacag catgagatac
    19681 agctcatttc accatatccg tctttagcca ttgttgttac accttcgtat tggatagaag
    19741 agtgtttgtg gctcatgtgc atacagtagc gacggaagtt gtatggcaat ttgtcagtcc
    19801 aaagaactgt caagtttggt tctggtgagt taccgatgtt gtcaagagtg ttcaagaaac
    19861 ggtagtccat cttagtaaca cggtgacgac cgtcgttacc cataccagcc atagaagttg
    19921 tgataaaggt tgggtcacct gagtacaatt ggtcataagc ttttgtacga gcaaatttaa
    19981 ctgtacgaag tttcataacg aaatcatcaa cgaattcttg gatttctgat tcagtaaatg
    20041 taccacgagc aaggtcacgt tctgcaaaga tgtccaatac gattggtaca cgacctagag
    20101 atgtagcagc accgttaatc acacggcaga cagccatgaa agcaatgtta acccattgga
    20161 ttgcttcttt cacgttcatc gctggtttgc gaacatcaac cccgtaaagg tcacccaggc
    20221 gaacaacttg ttgcaatgct tggtattgaa ggtttacttc ttcacgaaga cggattgttt
    20281 cttcatcgat ttctttgatt gcattccagt cgtttacttt ttcttgcatc aagtagtctg
    20341 caccgtaaag agcaagacgt gcgtaaacac cgatgatacg tccgcgtgag tatgcatctg
    20401 gaagaccagt tacagtgtgt gcgtgacgag cgcgacgaat atttgaagtg taggcacgga
    20461 aaataccgtc gttaactgtt gttacatatt tagtgaagat ttcgtgaaca gctgggtctg
    20521 gttcgtatcc attttctttt aaagtagttt cagccatacg gataccacct tttggcatga
    20581 agttcaattt gaagagttca tcattttgga taccaaagat aacttcattt tctttgtcga
    20641 taaatccagc agggatatca gcgatagatg ttggacgagt gtccattggg aaacgagttt
    20701 cttcgtagtg tgctttagtt tcttctacaa ttttcttgat gtgaagtgaa cgctctgttg
    20761 gtcctgcaag gaagctttcg tctccatcat aaggtgtgta gttagcttgt acaaagcgtg
    20821 atacacttgc tttttctttc caatctacgc ctttgaagcc ttcccaagct ttgtcaaaaa
    20881 tatcttgtgc ttcaacaact gtcttaacaa ccatattaat gtcctctttt ttctagtaac
    20941 agtcatctgt tacattcata agacaagtat accataaagt aaccgatttc aacaagtgca
    21001 aaatccctat ttttacactt tcttttctaa aacagtctat attttatttc aaactgtatt
    21061 atatttttga aaaaaataaa gtcctttttt ctttttttca gaaaaaaggg tataataaaa
    21121 gaaaataagc agtaacactc aatggaaatc gaaaagcaaa ctaggaagct agccgcaggc
    21181 tgctcaaagc actgctttga ggttgtaaat agaactgacg aagtcagctc aaaatactgt
    21241 tttgaggttg cagatggaag ctgacgtggt ttgaagagat ttttgaaaag tataaaaagg
    21301 tgctaggcat gttgattttt cctttgttaa atgatttgtc aagaaaaatc atccatattg
    21361 acatggatgc cttttttgct gcggtggaaa tcaaggataa tcctaaactc agaggaaaac
    21421 ctgtcattat tggaagcgac cctcgacaaa caggtgggcg gggagtcgtt tctacctgta
    21481 gctatgaggc tcgagctttt ggtgtccatt ctgccatgag ttccaaggaa gcttatgaac
    21541 gttgtcccca ggccgtcttt atctcaggaa attatgagaa atacaaagct gtgggactcc
    21601 agattcgagc tatttttaag cgctatacag atttgattga acccatgagt attgacgaag
    21661 cctatttgga tgtgacagaa aataaactcg gtatcaagtc agcggtcaaa attgctcgcc
    21721 tcattcaaaa agatatctgg caagaactcc atctaactgc ttctgccggt atttcctata
    21781 acaagttctt agctaaaatg gcgagtgatt atcaaaaacc tcatggtttg acagtgattc
    21841 tacctgaaca ggctgaggat tttctcaaac aaatggatat ttccaaattt catggagtag
    21901 gaaaaaagac agtagaacgt cttcatcaaa tgggcgtttt tactggtgct gatttacttg
    21961 aagttcctga ggtgacccta atagaccgtt ttggtagact aggctatgat ctgtatcgaa
    22021 aggctcgtgg cattcacaac tctccagtca aatccaatcg catccgtaaa tcaatcggca
    22081 aggagaaaac ctacgggaag attctccgtg ctgaggaaga tatcaaaaaa gagctgactc
    22141 ttctatcaga aaaagtcgct ctcaatctac atcaacaaga aaaagctgga aaaattgtca
    22201 ttttgaaaat ccgctacgag gacttttcaa ctcttaccaa acgaaaaagt attgctcaaa
    22261 aaacacaaga tgctagtcag ataagccaaa tagccctgca actctatgaa gaattaagcg
    22321 agaaagaaag aggtgtccgc ctattgggga ttaccatgac tggattttaa agctcaatga
    22381 aaatcaaaga gcaaactagg aggctagccg caggctgctc aaaacactgt tttgaggttg
    22441 cagataaagc tgacgcggtt tgaagagatt ttctaagagt ataaaacctt gaagagttgc
    22501 cccttcaagg tttttcttat acaaataaac ggacaaaact gtaaagtagc aaaacactac
    22561 caagcacgat acggtattta ccaaaaaggg tgaagtcgtg ttttttcaca tagctggtca
    22621 agaagcgaat agccaccatg ctgaccgcaa aagctactcc catcgcgacc aagagcaaaa
    22681 acaattgccc aaagctcaag agttctccgg ctttcacaaa tttgaaaatc tttaaggcac
    22741 tagctccaaa cataacggga atcccaagat agaaggtaaa ttctgtcaca actgaacgac
    22801 tggttccatt taacaaacca ccgacaatcg ttgcacctga acggctagtc cctggtaaaa
    22861 gagcaagaac ttggaagagt ccgatataga aagcggtcgt ataaggaagc ttgtccaact
    22921 ctgttacact tggctcgata gcacgcgctt tattgcgctt ttccaaatag atgaaggcaa
    22981 ccccgtagat aatcaacatg agagcaactg aaaccatgtt atggaagtgg gtatcaaacc
    23041 aatcatcaaa tttaaagaca ccaagtaaag gcaaagtggc aatcaagacc ttcaaccata
    23101 gtctccaagt cttacgaact tcctgtttgt ccttagtcgg tttaaaagga ttgagcttgt
    23161 taaaataaat caccataact gctaaaatag caccaagctg aatcacgaca ttaaacatgg
    23221 acataaaggc ttcattttga ttttggtatt ggataaactc ctctgctaaa atcaagtgac
    23281 ctgtactgga aatcggcaac cattccgtaa ttccttcaac aatcccgaag aagatagatt
    23341 ttaaaatttc aataagatac atatatttct ccttatatta tatttaacgc agttagctac
    23401 tgccaaagcc caagtggtat acttggaata agccactgtg gattagttca tttcctccaa
    23461 tcgcttgacg atttccgaaa gggtctaacc acagcttttt gtttcaattg gtaatgagtt
    23521 tgataacgca tagacgtttt atctcgtcta aggtaacaag gcaaaaagtt cgtggataac
    23581 caagtagact tgaaatacta tatctggagg tactcccatg ctttatgtgg gcattgatgt
    23641 cgctaaaaat aaacacgatg ttacagcctt gaatgttcga ggaaaactgt tcttaaacca
    23701 ctcacttttt caaataataa agctggtttt gaactcttag atctgtcttt tcgacagctc
    23761 aaccaagact gtctcatcgc tcttaaactt ctttctgacc ccaatcgtga acaatttcaa
    23821 cacgataatc ggcaagtaga actaaaaata ctggctagac atattcatcg tctcaagaaa
    23881 aaacagtctg attggaaagt acaatacact cgttgtcttg atatcatctt tcctgagttg
    23941 gataaaatcg ttggaaagca ttcagaatat acctaccaac tcttgacacg ctaccctaat
    24001 cctcagaaaa ggcttgaggc aagatttgat aagctgatag aaattaagcg attgaccgct
    24061 tctaaaattc aggatatcct ctcagtcgca cctcgttcta tcggaacaac atctcctgct
    24121 cgtgaattcg aaatcatcga aatcatcaaa cattacaaga ggctcattga caaggcggaa
    24181 acatgtgtca atgacttgat ggctgagttc aactcggtca tcacgacggt tactgggatt
    24241 gggggtcgtt taggggcggt cattttagcc gagattcgaa atattcatgc ctttgataat
    24301 cctgctcaat tacaagcttt cgctggactg gattcttcta tttatcagtc aggtcagatt
    24361 gatttagctg gaagaatgat caaacggggt tcccctcatc tgcggtgggc actcatacaa
    24421 gctgccaaag catgcgctcg cttttcacct gcttttaagg c
//
LOCUS       DAVLXH010000030        23830 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00028199
            SAMN33607166-rid17955573.denovo.030, whole genome shotgun sequence.
ACCESSION   DAVLXH010000030 DAVLXH010000000
VERSION     DAVLXH010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607166
            Sequence Read Archive: SRR23725544
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 23830)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23830)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721421.1
            Genome Coverage       :: 115x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:42:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,210
            CDSs (total)                      :: 2,161
            Genes (coding)                    :: 2,023
            CDSs (with protein)               :: 2,023
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 73 of 138
            Pseudo Genes (incomplete)         :: 60 of 138
            Pseudo Genes (internal stop)      :: 40 of 138
            Pseudo Genes (multiple problems)  :: 31 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23830
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607166-rid17955573.denovo.030"
                     /strain="AUSMDU00028199"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1349"
     gene            complement(111..3287)
                     /gene="carB"
                     /locus_tag="VYO11_001309"
     CDS             complement(111..3287)
                     /gene="carB"
                     /locus_tag="VYO11_001309"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HEV1595875.1"
                     /translation="MPKRTDIQKIMVIGSGPIIIGQAAEFDYAGTQACLSLKEEGYEV
                     VLVNSNPATIMTDKEIADKVYIEPITLEFVTRILRKERPDALLPTLGGQTGLNMAMEL
                     SKNGILDELGVELLGTRLSAIDQAEDRDLFKQLMEELEQPIPESEIVNTVEEAIAFAA
                     TIGYPVIVRPAFTLGGTGGGMCANEKELREITENGLKLSPVTQCLIERSIAGFKEIEY
                     EVMRDSADNALVVCNMENFDPVGIHTGDSIVFAPAQTMSDYENQMLRDASLSIIRALK
                     IEGGCNVQLALDPNSFKYYVIEVNPRVSRSSALASKATGYPIAKLAAKIAVGLTLDEV
                     INPVTGSTYAMFEPALDYVVAKIPRFPFDKFEKGERRLGTQMKATGEVMAIGRNIEES
                     LLKACRSLEIGVHHNEIPELAAVSDDALIEKVVKAQDDRLFYVSEAIRRGYTPEEIAE
                     LTKIDIFYLDKLLHIFEIEQELGAHPQDLEVLKTAKLNGFSDRKIAELWGTTDDQVRQ
                     LRLENKIVPVYKMVDTCAAEFDSETPYFYSTYGWENESIRSDKESVLVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQAAGYEAIIMNSNPETVSTDFSVSDKLYFEPLTFEDVMNVIDL
                     EQPKGVIVQFGGQTAINLAEPLAKAGVTILGTQVADLDRAEDRDLFEQALKELDIPQP
                     PGQTATNEEEAALAARKIGFPVLVRPSYVLGGRAMEIVENEEDLRSYMRTAVKASPDH
                     PVLVDSYIVGQECEVDAISDGKNVLIPGIMEHIERAGVHSGDSMAVYPPQTLSQKVQE
                     TIADYTKRLAIGLHCLGMMNIQFVIKDEKVYVIEVNPRASRTVPFLSKVTNIPMAQVA
                     TKLILGQSLSELGYQNGLYPESTRVHIKAPVFSFTKLAKVDSLLGPEMKSTGEVMGSD
                     ATLEKALYKAFEASYLHLPTFGNVVFTIADDAKEEALNLARRFQNIGYGILATEGTAA
                     FFASHGLQAQPVGKIGDDDKDIPSFVRKGRIQAIINTVGTKRTADEDGEQIRRSAIEH
                     GVPLFTALDTANAMLKVLESRSFVTEAI"
     gene            complement(3600..4679)
                     /gene="carA"
                     /locus_tag="VYO11_001310"
     CDS             complement(3600..4679)
                     /gene="carA"
                     /locus_tag="VYO11_001310"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HEV1595876.1"
                     /translation="MTKRILVLEDGTVFEGKAFGADIDVTGEIVFNTGMTGYQESITD
                     QSYNGQILTFTYPLVGNYGINRDDYESIIPTCKGVVVFEEARRASNWRNQMTLDEFLK
                     AKKIPGISGIDTRDLTKIIRKHGTMRATLTHVGDSMDHVTDQLQATVLPTDNIKQVST
                     KTSYPAPGVGLSVVLVDFGLKHSILRELSKRNCNVTVVPYSTTAEEILHLNPDGVMLS
                     NGPGNPEDVPQALDMIRGVQGKIPIFGICMGHQLFAMANGAKTYKMKFGHRGFNHAVR
                     EIATGRVDFTSQNHGYAVSREDLPEHLIITHEEINDKSVEGVRHRYQPAFSVQYHPDA
                     APGPHDASYLFDEFIEMMEVFKQSN"
     gene            complement(4729..5652)
                     /locus_tag="VYO11_001311"
     CDS             complement(4729..5652)
                     /locus_tag="VYO11_001311"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001293822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HEV1595877.1"
                     /translation="MSENQQALNHVVSMEDLTVDQVMKLIKRGIEFKNGAQLPYEDHP
                     IVSNLFFEDSTRTHKSFEVAEIKLGLERLDFDVKTSSVNKGETLYDTILTLSALGVDV
                     CVIRHPEVDYYRELIASPTITTSIINGGDGSGQHPSQSLLDLMTIYEEFGHFEGLKVA
                     IAGDLDHSRVAKSNMQILKRLGSELFFAGPEEWRSQEFADYGQFVTIDEIIDQVDVMM
                     FLRVQHERHDSGAVFSKEDYHAQHGLTQERYDRLKETAILMHPAPINRDVEIADHLVE
                     APKSRIVQQMTNGVFVRMAILESVLASRNAN"
     gene            complement(5671..6192)
                     /gene="pyrR"
                     /locus_tag="VYO11_001312"
     CDS             complement(5671..6192)
                     /gene="pyrR"
                     /locus_tag="VYO11_001312"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HEV1595878.1"
                     /translation="MKTKEVVDELTVKRAITRITYEIIERNKDLNKIVLAGIKTRGVF
                     IAHRIQERLKQLENLSVPVVELDTKPFRDDVKSGEDTSLVSVDVTDREVILVDDVLYT
                     GRTIRAAIDNIVGHGRPARVSLAVLVDRGHRELPIRPDYVGKNIPTSRSEEIIVEMTE
                     LDDQDRVLITEEA"
     gene            complement(6403..7032)
                     /gene="nth"
                     /locus_tag="VYO11_001313"
     CDS             complement(6403..7032)
                     /gene="nth"
                     /locus_tag="VYO11_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000244461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HEV1595879.1"
                     /translation="MVLSKKRARKVLEEIIALFPDAKPSLDFTNHFELLVAVMLSAQT
                     TDAAVNKATPGLFVAFPTPQAMSVATESEIASHISRLGLYRNKAKFLKKCAQQLLDDF
                     DGQVPQTREELESLAGVGRKTANVVMSVGFGIPAFAVDTHVERICKHHDIVKKSATPL
                     EVEKRVMDILPPEQWLAAHQAMIYFGRAICHPKNPECDQYPQLYDFSNL"
     gene            complement(7032..7574)
                     /locus_tag="VYO11_001314"
     CDS             complement(7032..7574)
                     /locus_tag="VYO11_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HEV1595880.1"
                     /translation="MKLNIQEIRKQSEGLNFEQTLDLVDDLRARNQEILDVKDILAVG
                     KVQYEDRMYFLDYQLSYTIVLASSRSMEPVELVESYPVTEVFMEGATNHLNQEILDDD
                     LVLPIENEALDLAESVSDNILLNIPIKVLTAEEEAGQGFISGNDWQIMTEEEYQAQKA
                     VKKEENSPFAGLQGLFDGDE"
     gene            7744..8061
                     /locus_tag="VYO11_001315"
     CDS             7744..8061
                     /locus_tag="VYO11_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000389556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
                     /protein_id="HEV1595881.1"
                     /translation="MEDKKLIQLLSKLNKSYQNCKQGTADDIRLQELLNTTMQELKKT
                     EKLNNSILIDLEKFYQPTSLLIGLGSLKLNDQARTAWRNYDKFHYEHVKHVLSLYGPV
                     FGF"
     gene            8300..9859
                     /locus_tag="VYO11_001316"
     CDS             8300..9859
                     /locus_tag="VYO11_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEV1595882.1"
                     /translation="MHYEHSRKGNHMIKINHLTITQNKDLRDLVSDLSMTIQDGEKVA
                     IIGEEGNGKSTLLKILMGEALSDFTIKGNIQSDYQSLAYIPQKLPEELKKKTLHDYFF
                     LDSIDLDYSILYRLAEELHFDSNRFASDQKIGNLSGGEALKIQLIHELAKPFEILFLD
                     EPSNDLDLETVDWLKGQIQKTRQTVIFISHDEDFLSETADTIVHLRLVKHRKEAETLV
                     EHLDYESYSEQRKANFAKQSQQAANNQRAYDKTMEKHRRVKQNVETALRATKDSTAGR
                     LLAKKMKTVLSQEKRYEKAAQSMTQKPLEEEQIQLFFSDIQPLPASKVLVQLEKENLS
                     IDDRVLVQKLQLTVRGQEKIGIIGPNGVGKSTLLAKLKQLLNDKREISLGFMPQDYHK
                     KLQLDLSPIAYLSKTGEKEELQKIQSHLASLNFSYPEMQHQIRSLSGGQQGKLLLLDL
                     VLRKPNFLLLDEPTRNFSPTSQPQIRKLFATYPGGLITVSHDRRFLKEVCSSIYRLTE
                     HGLELVNLEDV"
     gene            complement(9903..10802)
                     /gene="htpX"
                     /locus_tag="VYO11_001317"
     CDS             complement(9903..10802)
                     /gene="htpX"
                     /locus_tag="VYO11_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease HtpX"
                     /protein_id="HEV1595883.1"
                     /translation="MLFDQIASNKRKTWILLLVFFLLLALVGYAVGYLFIRSGLGGLV
                     IALIIGFIYALSMIFQSTEIVMSMNGACEVDEQTAPDLYHVVEDMALVAQIPMPRVFI
                     IDDPALNAFATGSNPQNAAVAATSGLLAIMNREELEAVMGHEVSHIRNYDIRISTIAV
                     ALVSAITMLSGMAGRMMWWGGAGRRRSDDDRDGNGLEIIMLVVSLLAIVLAPLAATLV
                     QLAISRQREFLADASSVELTRNPQGMINALDKLDNSKPMSRHVDDASSALYINDPKKG
                     GGFQKLFYTHPPISERIERLKQM"
     gene            complement(10804..11364)
                     /locus_tag="VYO11_001318"
     CDS             complement(10804..11364)
                     /locus_tag="VYO11_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LemA family protein"
                     /protein_id="HEV1595884.1"
                     /translation="MTWIILGVLALVVIFVIVSYNGLVKNRMQTKEAWSQIDVQLKRR
                     NDLLPNLIETVKGYAKYEGSTLEKVAELRNQVAAATSPAEAMKASDALTRQVSGIFAV
                     AESYPDLKASANFVKLQEELTNTENKISYSRQLYNSVVSNYNVKLETFPSNIIAGMFG
                     FKAADFLQTPEEEKSVPKVDFSGLGD"
     gene            11458..12171
                     /gene="rsmG"
                     /locus_tag="VYO11_001319"
     CDS             11458..12171
                     /gene="rsmG"
                     /locus_tag="VYO11_001319"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HEV1595885.1"
                     /translation="MKPKTFYNLLAEQNLPLSDQQKEQFERYFELLVEWNEKINLTAI
                     TDKEEVYLKHFYDSIAPILQGLIPNETIKLLDIGAGAGFPSLPMKILYPELDVTIIDS
                     LNKRINFLQLLAQELDLNGVHFYHGRAEDFAQDKNFRAQYDFVTARAVARMQVLSELT
                     IPYLKVGGKLLALKASNAPEELLEAKNALNLLFSKVEDNLSYALPNRDPRYITVVEKK
                     KETPNKYPRKAGMPNKRPL"
     gene            12523..13806
                     /locus_tag="VYO11_001320"
     CDS             12523..13806
                     /locus_tag="VYO11_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007554578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HEV1595886.1"
                     /translation="MKQESTVDLLLDVDQRPSDGKGILLSFQHVFAMFGATILVPLIL
                     GMPVSVALFASGVGTLIYMIATGFKVPVYLGSSFAFITAMSLAMKEMGGDVSAAQTGV
                     ILTGLVYVLVATSIRFVGTKWIDKLLPPIIIGPMIIVIGLGLAGSAVTNAGLVADGNW
                     KNALVAVVTFLIAAFINTKGKGFLRIIPFLFAIIGGYLFALTLGLVDFTPVLKANWFE
                     IPGFYLPFSTGGAFKEYNLYFGPEAIAILPIAIVTISEHIGDHTVLGQICGRQFLKEP
                     GLHRTLLGDGIATSVSAFLGGPANTTYGENTGVIGMTRIASVSVIRNAAFIAIALSFL
                     GKFTALISTIPNAVLGGMSILLYGVIASNGLKVLIKERVDFAQMRNLIIASAMLVLGL
                     GGAILKLGPVTLSGTALSAMTGIILNLILPYENKD"
     gene            complement(14001..15572)
                     /gene="ffh"
                     /locus_tag="VYO11_001321"
     CDS             complement(14001..15572)
                     /gene="ffh"
                     /locus_tag="VYO11_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HEV1595887.1"
                     /translation="MAFESLTERLQNVFKNLRKKGKISESDVQEATKEIRLALLEADV
                     ALPVVKDFIKKVRERAVGHEVIDTLNPAQQIIKIVDEELTAVLGSDTAEIIKSPKIPT
                     IIMMVGLQGAGKTTFAGKLANKLKKEENARPLMIAADIYRPAAIDQLKTLGQQIDVPV
                     FALGTEVPAVEIVRQGLEQAQTNHNDYVLIDTAGRLQIDELLMNELRDVKALAQPNEI
                     LLVVDAMIGQEAANVAREFNAQLEVTGVILTKIDGDTRGGAALSVRHITGKPIKFTGT
                     GEKITDIETFHPDRMSSRILGMGDMLTLIEKASQEYDEQKALEMAEKMRENTFDFNDF
                     IDQLDQVQNMGPMEDLLKMIPGMANNPALQNMKVDERQIARKRAIVSSMTPEERENPD
                     LLNPSRRRRIAAGSGNTFVEVNKFIKDFNQAKQLMQGVMSGDMNKMMKQMGINPNNLP
                     KNMPNMGGMDMSALEGMMGQGGMPDLSALGGAGMPDMSQMFGGGLKGKIGEFAMKQSM
                     KRMANKMKKAKKKRK"
     gene            complement(15584..15916)
                     /locus_tag="VYO11_001322"
     CDS             complement(15584..15916)
                     /locus_tag="VYO11_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009660419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HEV1595888.1"
                     /translation="MEIEKTNRMNALFEFYAALLTDKQMNYIELYYADDYSLAEIAEE
                     FGVSRQAVYDNIKRTEKILEDYEMKLHMYSDYIVRSQIFDQILERYPKDNFLQEQIEI
                     LTSIDNRE"
     gene            complement(16007..16384)
                     /locus_tag="VYO11_001323"
     CDS             complement(16007..16384)
                     /locus_tag="VYO11_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HEV1595889.1"
                     /translation="MKIRMRNTIQFDEQLEVIDQLYDVEVHEKGDYSYLLFYNEEKEK
                     VVIKFHGQELVMSRFSNPKTIMRFLKDSDSLAYIPTPMGMQEFTIQTSHYQVDRQKIE
                     LDYQLQNQEGHPFASYQLEITWG"
     gene            16456..17760
                     /locus_tag="VYO11_001324"
     CDS             16456..17760
                     /locus_tag="VYO11_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEV1595890.1"
                     /translation="MNEKVFRDPVHNYIHVNNQIIYDLINTKEFQRLRRIKQLGTSSY
                     TFHGGEHSRFSHCLGVYEIARRITEIFEEKYPEEWNPAESLLTMTAALLHDLGHGAYS
                     HTFENLFDTDHEAITQEIIQNPETEIHQVLLQVAPDFPEKVASVIDHTYPNKQVVQLI
                     SSQIDADRMDYLLRDSYFTGASYGEFDLTRILRVIRPIENGIAFQRNGMHAIEDYVLS
                     RYQMYMQVYFHPATRAMEVLLQNLLKRAKELYPEDKDFFARTSPHLLPFFEKNVTLTD
                     YLALDDGVMNTYFQLWMTSPDKILADLSQRFVNRKVFKSISFSQEDQDQLASMRKLAE
                     DIGFDPDYYTAIHKNFDLPYDIYRPESENPRTQIEILQKNGELAELSSLSPIVQSLAG
                     SRHGDNRFYFPKEMLDQNSIFASITQQFLHLIENDHFTPNKN"
     gene            17773..18579
                     /gene="yidA"
                     /locus_tag="VYO11_001325"
     CDS             17773..18579
                     /gene="yidA"
                     /locus_tag="VYO11_001325"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000023490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HEV1595891.1"
                     /translation="MSIKLIAVDIDGTLVNSQKEITPEVFSAIQDAKEAGVKVVIATG
                     RPIAGVAKLLDDLQLRDQGDYVVTFNGALVQETATGHEIISESLTYEDYLDMEFLSRK
                     LGVHMHAITKDGIYTANRNIGKYTVHESTLVSMPIFYRTPEEMAGKEIVKCMFIDEPE
                     ILDAAIEKIPAEFYEHYSINKSAPFYLELLKKNVDKGSAITHLAEKLGLTKDETMAIG
                     DEENDRAMLEVVGNPVVMENGNPEIKKIAKYITKTNDESGVAHAIRTWVL"
     gene            18622..19620
                     /locus_tag="VYO11_001326"
     CDS             18622..19620
                     /locus_tag="VYO11_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001008999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAP domain-containing protein"
                     /protein_id="HEV1595892.1"
                     /translation="MNFFSKLFNLKQNNHNRDTNSDCNNFYLNELECGLTPGQLILID
                     WTQKTGRNYNFPRYFKYSLQIDPESTHNQLYKLGYFTKNKTLSYLTVVELKTILSKHN
                     LATSGKKAELITRIINNVNIDNLDIPFEFKLTKEAQNLIIEHSDYIKAYYDKDITMED
                     YCKEKNNISFKATFGDIKWSLLNKQAHRNTVSGDFGCLSNTRKAQGRHLEQEGNIKHA
                     LIYYIESLIITISGLENNFSATDYPVYYPDSIPDYSLKHIQTLMESLSDDDYDFAFDE
                     ALFRFSILNANHFLSKEDIDYLRVNLPRSTAEEINNYLKKYECYSPLNNLELDDFE"
     gene            complement(19787..19858)
                     /locus_tag="VYO11_001327"
     tRNA            complement(19787..19858)
                     /locus_tag="VYO11_001327"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19823..19825),aa:Arg,seq:cct)
     gene            complement(19900..20247)
                     /gene="rplS"
                     /locus_tag="VYO11_001328"
     CDS             complement(19900..20247)
                     /gene="rplS"
                     /locus_tag="VYO11_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HEV1595893.1"
                     /translation="MNPLIQSLTEGQLRTDIPSFRPGDTVRVHAKVVEGNRERIQIFE
                     GVVIARKGAGISENYTVRKISNGVGVERIFPIHTPRVEKIEVVRYGKVRRAKLYYLRA
                     LQGKAARIKEIRR"
     gene            complement(20366..20695)
                     /gene="crcB"
                     /locus_tag="VYO11_001329"
     CDS             complement(20366..20695)
                     /gene="crcB"
                     /locus_tag="VYO11_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000237393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HEV1595894.1"
                     /translation="MVIVYLAIACGLGALVRYFFSRYNQASKLPLGTLIANLLGCFLI
                     GVFYNHVESKEVYAILATGFCGGLTTFSTLNDELQRLLSDKKVFYSYLTLTYIGGLVA
                     IFLGILL"
     gene            complement(20689..21063)
                     /gene="crcB"
                     /locus_tag="VYO11_001330"
     CDS             complement(20689..21063)
                     /gene="crcB"
                     /locus_tag="VYO11_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HEV1595895.1"
                     /translation="MKKEQFYPLGIFLAAMLGGLVRYLVSTWLPASPDFPWGTLFVNY
                     LGIFCLIYLVKGYLVYKGTSKGLILALGTGFCGGLTTFSSLMLDTVKLLDTGRYLSLI
                     LYLLLSIGGGLLLAYYLGRKKW"
     gene            complement(21060..21326)
                     /locus_tag="VYO11_001331"
     CDS             complement(21060..21326)
                     /locus_tag="VYO11_001331"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HEV1595896.1"
                     /translation="MDLDIIRQEIDQIDDQIVKLLEERMHLVEGVVAYKKASGKPILD
                     TKREAVIFEKVRSRVEDKRYQETIVATFSDILKRSRDYQDQNIK"
     gene            complement(21442..21885)
                     /locus_tag="VYO11_001332"
     CDS             complement(21442..21885)
                     /locus_tag="VYO11_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HEV1595897.1"
                     /translation="MALAKIVFASMTGNTEEIADIVADKLRDLGLDVDVDECTTVDAS
                     DFLEADIAIVATYTYGDGELPDEMMDFYEDLADLNLNGKIYGVVGSGDTFYDEFCKAV
                     DDFDRVFVSTGAEKGSECVKVDLSAEEEDIERLEQFAEELVAKVG"
     gene            21989..22924
                     /locus_tag="VYO11_001333"
     CDS             21989..22924
                     /locus_tag="VYO11_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HEV1595898.1"
                     /translation="MEICQQILEKIKEYDTIIIHRHMKPDPDALGSQVGLKALLEHHF
                     PEKTIKAVGFDEPTLTWMAEMDLVEDRAYQGALVIVCDTANTARIDDKRYSQGDFLIK
                     IDHHPNDDVYGDLSWVDTSSSSASEMITLFAQTTQLALADRDAELLFAGIVGDTGRFL
                     YPSTTARTLRLAAYLREHNFDFAALTRKMDTMSYKIAKLQGYIYDHLEVDENGAARVI
                     LSQEVLKQYNVTDAETAAIVGAPGRIDRVSLWGIFVEQADGHYRVRLRSKVHPINEIA
                     KEHDGGGHPLASGANSYSLEENEIIYQKLKNLLKN"
     gene            22978..23262
                     /locus_tag="VYO11_001334"
     CDS             22978..23262
                     /locus_tag="VYO11_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HEV1595899.1"
                     /translation="MARKETMAERKYCKMKKDIHPEYRPVVFMDTTTGYQFLSGSTKR
                     SNETVEFEGETYPLIRVEISSDSHPFYTGRQKFTQADGRVDRFNKKYGLK"
     gene            complement(23319..23807)
                     /locus_tag="VYO11_001335"
     CDS             complement(23319..23807)
                     /locus_tag="VYO11_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001835775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron permease"
                     /protein_id="HEV1595900.1"
                     /translation="MSSYFVKITDASKAVKNGDQAEVQKLVTKMASDFERVENKDSEV
                     GKIVKEKLALSGDITEAKLTEISSALLAFEKEQNPVDLDAEKEKLVNRLSPRFETLEQ
                     AIASKDLEKVREAFKKMNSTWTINESVVRDNSTAHYGRVETAISFLPSSMETEPTDES
                     GT"
BASE COUNT         7131 a         5266 c         4485 g         6948 t
ORIGIN      
        1 tgaaataaga tgcgaacgaa tcaattagaa aattcaaatt aatttctaga aatattttag
       61 tatccctgtg tactgttcta aattcagtct gctatacctt atttttctat ttaaatcgct
      121 tctgtaacaa agctacgact ttcaagtacc ttaagcatgg cattagctgt atctagcgct
      181 gtgaagaggg gcaccccgtg ttcaatggct gaacgacgaa tttgctcacc atcttcgtca
      241 gcagttcgtt ttgttcctac tgtgttaatg atagcttgaa ttcttccttt gcgtacaaaa
      301 cttgggatat ccttatcatc atcaccaatc ttaccaacag gttgggcttg caagccatga
      361 ctagcaaaga aggctgctgt cccttctgtc gcaaggattc cataaccaat gttttggaaa
      421 cgacgagcca agttcaaggc ttcttctttg gcatcatcag cgatggtaaa gacgacatta
      481 ccaaaagttg gcaagtgtag ataagaagct tcaaaggctt tatagagagc tttttccaaa
      541 gtagcatcag aacccataac ttcacctgtt gacttcattt caggaccgag caagctgtct
      601 accttagcta gtttggtaaa ggagaagaca ggtgccttga tatgaacacg ggtgctttca
      661 gggtaaagtc cattttggta gccaagttct gataaacttt gaccaagaat gagcttggtc
      721 gctacttgag ccataggaat attggttacc ttagatagga atggaactgt acggctggca
      781 cgtggattga cctcaataac gtagactttt tcatccttga taacaaactg gatgttcatc
      841 attccaaggc agtgaagacc gattgctaag cgtttggtgt agtctgcgat ggtctcctga
      901 accttttgcg acaaggtttg tggtgggtaa acagccattg agtcacctga gtggacacca
      961 gcacgttcga tatgctccat aataccagga atgagtacat ttttaccatc tgaaatggca
     1021 tcaacttcgc actcttgccc aacgatgtaa gagtcgacaa gaactgggtg gtctggacta
     1081 gccttaacag cagttcgcat gtaagaacga aggtcttctt cgttttcaac gatttccatg
     1141 gcacgtccac caagtacata agatgggcgg acaagaactg ggaagccaat cttacgagct
     1201 gcaagagctg cttcttcttc attggtagcc gtttgtcctg gtggctgtgg aatatccaat
     1261 tctttgagag cttgctcgaa gaggtcacgg tcttcggcac ggtctaggtc agcaacctgt
     1321 gtaccaagga tggtcacacc tgcttttgcc aatggctccg caaggttgat ggctgtttga
     1381 ccaccgaact gaacgataac tccctttggt tgttccaagt caatgacgtt cataacatct
     1441 tcgaatgtca atggctcaaa gtaaagctta tctgatacag agaagtctgt tgaaacggtc
     1501 tctgggtttg agttcatgat aatagcttca taaccagctg cctggatagc cttaacagag
     1561 tgaacggttg cgtagtcaaa ctcaacccct tgaccgatac ggattggacc tgaacctagg
     1621 acaagtacag attctttatc agatctgata gattcatttt cccaaccata ggttgaatag
     1681 aaatatggcg tttcagagtc gaactctgcc gcacaagtgt ctaccatctt ataaactggg
     1741 acaatcttgt tttccaaacg aagttggcga acttgatcat cagtcgttcc ccagagttca
     1801 gcaatcttac ggtctgaaaa accattaagt ttggctgttt tcaaaacttc tagatcttgt
     1861 ggatgagcac ccaattcttg ctcaatttca aagatatgca agagtttatc aagatagaag
     1921 atatcaattt ttgtaagctc tgcaatttct tcaggtgtgt aaccacggcg aatggcttct
     1981 gacacataga agagacggtc atcttgggct ttgacaacct tttcaatcaa ggcatcatca
     2041 gaaactgctg caagttcagg tatttcattg tggtgcaccc caatttcaag ggagcggcag
     2101 gccttgagaa gagattcctc gatgttacga ccgattgcca tgacttctcc agtcgccttc
     2161 atttgtgtac cgagacggcg ttcacccttt tcaaacttgt caaatgggaa acgtggaatc
     2221 ttagcaacta cgtagtcaag ggctggttca aacatggcat aggttgaacc tgtaactggg
     2281 tttataacct catccaaggt caaacctact gcaatcttgg cagccaactt agcaatcgga
     2341 tatcctgtcg ctttagaagc aagggctgac gaacgtgata cacgagggtt tacttcgata
     2401 acataatact tgaagctgtt aggatcaaga gctagctgaa cattacatcc accttcaatc
     2461 ttgagggcac gaataatgct caagctcgca tcacgaagca tttggttttc atagtctgac
     2521 atggtttgcg caggggcaaa tacaatggaa tcccctgtgt gaatcccaac tgggtcaaag
     2581 ttttccatgt tacaaacaac caaggcattg tcagctgagt cacgcatcac ttcgtattca
     2641 atttccttga aaccggcaat cgaacgctca atcaaacatt gggtaacagg tgacaatttc
     2701 aaaccatttt cagtgatttc acgcaattct ttctcgttgg cacacatacc accaccagta
     2761 ccaccaaggg taaaggctgg acgaacgatg actgggtagc caattgtcgc tgcaaaggca
     2821 attgcttctt ctactgtgtt aacaatttca gattctggaa tgggttgctc aagctcttcc
     2881 atcaattgtt taaagaggtc acggtcctcc gcttggtcaa tggcagacaa tctagtaccg
     2941 agaagctcta caccaagctc atctaagatg ccatttttag acaattccat ggccatgttg
     3001 agacctgtct gaccaccgag tgttggtagc aaggcatctg gacgttcctt acgaagaata
     3061 cgtgtcacaa actcaagtgt aatcggttca atgtaaacct tatcagcaat ttccttgtcc
     3121 gtcatgatgg ttgcaggatt tgagttaacc aaaacaacct cataaccttc ctctttcaac
     3181 gacaagcaag cctgggtccc agcgtagtca aactcagcag cctgaccaat aataatcgga
     3241 ccagaaccaa tcaccataat tttttgaata tcagtacgtt taggcatata taagatatta
     3301 agggcgtcaa gcggacaaag ctaaaatagg agttatgacg aagaactgtc agttctagga
     3361 ataactatct ttttagcacc atccgtagcc cgtattcagt tcagcaaata cggagcaccc
     3421 ttctcctttc tattcgtcgc ctctcagggc gacattaaat aagatacaaa ggacgaatag
     3481 aaagcgattg aattttagaa aatcaaggaa ggattgacaa tccaagttgg tttctctaca
     3541 ttctgagctt tccgtccgtg ttcagttaca taaattctcc gacgagcttt tactcgttct
     3601 tagtttgatt gtttaaaaac ttccatcatc tcgataaact cgtcaaatag gtagctagcg
     3661 tcgtgtggcc caggagctgc atctgggtgg tattgaacag agaaagcagg ttggtatctg
     3721 tggcgcacac cttccactga cttgtcattg atttcttcgt gggtaataat caagtgctct
     3781 ggcaaatcct cgcggctgac tgcataacca tggttctggc tggtgaagtc tactcgtcct
     3841 gttgcgattt cacgtaccgc atggttgaat ccacggtggc caaacttcat cttataggtc
     3901 ttagccccgt ttgccattgc aaagagttgg tgtcccatac aaataccaaa gattggaatt
     3961 tttccttgta caccgcgaat catgtcgagt gcttgtggaa cgtcttctgg gttacctgga
     4021 ccatttgaca acataactcc atcaggattg agatggagaa tttcttcagc cgttgtcgaa
     4081 taaggaacaa ctgtcacgtt acagttgcgt ttagaaagtt cacgtaggat tgagtgcttg
     4141 agaccaaagt ccactagcac cacgctcaaa ccaactcctg gagctggata agacgtttta
     4201 gtagaaacct gtttgatatt gtctgtcggt aaaactgttg cttggagctg gtccgtcaca
     4261 tggtccatac tgtccccaac atgggtcaag gttgcacgca tagtaccatg cttacggata
     4321 atcttggtaa gatcacgcgt atcaattcct gaaatccctg gaattttctt ggctttcaaa
     4381 aattcatcca aggtcatttg gttgcgccag ttgctagctc tacgcgcttc ttcaaaaaca
     4441 acgactccct tacaagttgg aataatggat tcataatcat cacgattaat accataattt
     4501 cctaccaaag gataagtaaa ggtcaagatt tgtccattat aagactggtc tgtaatggat
     4561 tcttggtagc cggtcatccc tgtattaaag acgatttcgc ctgttacatc aatatctgct
     4621 ccgaaggcct tgccttcaaa aactgtgcca tcttctaata ctagaattct ttttgtcata
     4681 ttttcacctc tcgtggacgc tcactggcgt cttttaacgt cttgtgtttt agttggcgtt
     4741 tctactcgct agtacggatt ctaagattgc cattcgaaca aagacaccat tggtcatttg
     4801 ttggacaatc cgtgattttg gtgcttcaac caagtggtct gctatttcta catcacgatt
     4861 gattggagct gggtgcatga ggattgctgt ttctttcaaa cgatcgtaac gttcttgagt
     4921 caagccatgt tgggcatggt agtcttcttt tgaaaataca gctccactat catggcgttc
     4981 gtgttgcaca cggagaaaca tcatgacatc aacctgatca atgatttcat caatggttac
     5041 aaactgtcca tagtctgcaa actcttgact tctccattcc tcaggtccag cgaaaaagag
     5101 ttcagatccc aagcgtttca aaatctgcat attggatttg gcaacgcgtg agtggtccaa
     5161 gtcacctgca atagcaactt taagaccctc aaagtggcca aattcctcat aaatggtcat
     5221 caaatcaagc aagctctggc tagggtgttg gcccgaacca tctccaccat tgatgatgga
     5281 agtcgtaatc gttggactag caatcaattc tctatagtag tcgacctctg gatggcgaat
     5341 cacacagaca tccactccta aagcagacag agtcaaaatg gtgtcataaa gtgtctcacc
     5401 cttattaacc gaactagtct tcacatcaaa gtcaagtcgt tccaatccaa gtttaatctc
     5461 tgcgacttca aaggacttat gtgtccgtgt agaatcctca aagaagagat tggaaacaat
     5521 cggatggtct tcatagggaa gctgggctcc atttttaaac tcaattcctc gcttgatcaa
     5581 tttcattact tgatcgacag tgaggtcttc catggacacc acatggttca atgcttgttg
     5641 attttctgac atggctactc ctttaacttt ctaagcttct tcagtaatca gaactctgtc
     5701 ttggtcatca agttctgtca tctctacgat gatttcttca gaacgactgg ttgggatatt
     5761 ttttccaacg taatctggac ggattggcaa ttctctatgt ccacgatcga ctagaactgc
     5821 taaactcaca cgcgcaggac gaccatgacc gacaatatta tcaatagcag cacggatggt
     5881 acgacctgta tagagcacat catccaccaa gataacttcg cggtctgtca catcgacaga
     5941 aaccaaagaa gtatcttctc cacttttaac atcatcacgg aaaggtttag tatccaattc
     6001 cacaacagga actgaaagat tttctaactg cttcaaacgt tcttggattc ggtgggcaat
     6061 aaagacacca cgagttttaa taccagccaa gacgatctta ttcaaatctt tgttgcgttc
     6121 gataatctca taagtaatac gcgtaatcgc tcgtttgacg gtcaattcgt ctacaacttc
     6181 ttttgttttc atgacaaacc tccaaaaaga aaagtctcct taaacaagga gacttgaaat
     6241 ttatagccaa gcgagcccta ctgcacacag tatagacttc acccttctac tttatcgcgc
     6301 tccttgcctg cctcacggga caggtttaaa ggaatattta gttatcattt actatagcac
     6361 aaagcatgct taaaatcaag caaaaagttt caatgtagca tcttacaaat tgctaaaatc
     6421 atataattgt gggtactggt cacactctgg attttttgga tggcaaatgg ctcttccaaa
     6481 ataaatcatg gcctgatggg cagctaacca ctgctcaggc ggcaagatat ccatgacccg
     6541 cttttccacc tcaagtggcg tcgctgattt tttgacaata tcgtggtgtt tgcaaatacg
     6601 ctccacatga gtatccactg caaaggctgg aatcccaaat cctacactca tgacaacatt
     6661 ggctgtcttg cgaccaacac ctgccaaact ctccaattct tcacgtgtct gagggacttg
     6721 accatcaaaa tcgtctagta actgttgggc acatttttta aggaatttag ctttattccg
     6781 atacaatccc aagcgagaaa tatgtgaagc aatctcactc tctgtcgcta cagacatagc
     6841 ttggggtgtt ggaaaggcaa caaagagacc tggtgtggcc ttatttaccg ctgcatctgt
     6901 cgtctgggct gataacatga ccgcaaccag gagttcaaaa tgattggtaa aatcaagact
     6961 aggcttggca tctgggaaga gggcaatgat ttcttctagc acctttcgtg ctcgtttttt
     7021 tgacaagacc attattcatc tccgtcaaat agtccttgta agccagcaaa aggactgttt
     7081 tcttctttct ttactgcttt ttgagcttgg tattcttcct ctgtcatgat ttgccagtca
     7141 tttcctgaga taaatccttg accagcttct tcttcagccg tcaagacctt gataggaatg
     7201 tttagcagga tattgtctga tacactctca gcaaggtcaa gcgcctcatt ttcgatgggc
     7261 aagaccaagt catcatctaa aatttcttga tttagatggt tagttgcacc ttccatgaaa
     7321 acttccgtga ctggataaga ttcaactaac tcaactggct ccatactgcg actcgaagca
     7381 agaacaatgg tataagatag ttgataatct aagaaataca tacggtcttc atattgtact
     7441 ttcccaactg caaggatatc ttttacatct aaaatttctt gattacgtgc acgcaggtca
     7501 tcaactaaat ctaacgtttg ttcaaagttc aaaccttcag actgcttacg aatttcttga
     7561 atatttaatt tcatacttcc tccataaaga tttactctct tgattatacc atgaaaaggc
     7621 tacaaatcag cacaccaaac tttgtaatta aaattcaaaa ttttaacata tttactatga
     7681 cagttttgtt ttttagtgct atactatagg gaaagagtac atcagatcaa ggaggatgct
     7741 cacatggaag acaagaaact cattcaactc ctatccaagt taaataaaag ctatcaaaac
     7801 tgtaaacagg gtacggcaga tgatattcga ctacaagagc tgctaaacac tactatgcaa
     7861 gagctcaaaa aaacggaaaa gttgaacaac agtatcttaa ttgatcttga gaaattttac
     7921 caacccacca gtcttctgat tggactgggt agcctaaaac taaacgatca agcacgcact
     7981 gcttggcgaa actatgataa attccattac gagcatgtca aacacgtact aagtctctat
     8041 ggacctgttt ttggatttta gagcatagaa tttccagttt tctgttgaca aaatttcctt
     8101 aaaggtataa tataaagata ctaatactcg gaggtaaggg agacatgaac aactaagtct
     8161 atcaaataaa gaacctttat ttagtagatc ttgtttttgt ctctttttgt gtgctctttt
     8221 atgctctttt tctggcatgt taatagagtt tttttgacat agactttggg ctctactagg
     8281 taaagtagag ctttttgtta tgcactatga acattctaga aagggaaatc atatgataaa
     8341 aatcaatcat ctaaccatca cacaaaacaa agatttacga gatcttgtat ctgacctaag
     8401 catgaccatc caagacgggg aaaaggttgc tattattggt gaagaaggaa atggcaaatc
     8461 aaccttactt aaaattttaa tgggggaagc tttgtctgat ttcactatca agggaaacat
     8521 ccaatctgac tatcagtcac tggcctacat tcctcaaaaa cttcccgagg agctgaaaaa
     8581 gaaaacttta cacgactact tctttttaga ttctattgat ttagactaca gtatcctcta
     8641 tcgtttggcg gaggaattgc attttgatag caatcgtttc gcaagtgacc aaaagattgg
     8701 caatctatca gggggagaag ctttgaaaat tcagcttatc catgagttag ccaaaccctt
     8761 tgagattcta tttttagatg aaccttcaaa tgacctagac cttgagacag ttgattggct
     8821 aaaaggccag attcaaaaga ccaggcaaac cgttattttc atttcccatg atgaagactt
     8881 tctttctgaa acggcagaca ctattgttca cttgcgactg gtcaaacacc gtaaagaagc
     8941 ggaaacgcta gtagagcatt tagactatga aagctatagt gagcagagaa aggctaattt
     9001 tgccaaacaa agtcagcaag ctgctaacaa ccaaagagcc tacgataaaa ccatggaaaa
     9061 acatcggaga gtcaaacaaa atgtagaaac tgcgcttcga gctaccaaag acagtactgc
     9121 cggtcgccta ttggctaaaa agatgaaaac tgtcctctca caagaaaaac gctacgaaaa
     9181 ggcagctcag tccatgactc aaaagccact tgaagaggaa caaatccaac ttttcttttc
     9241 agacatccaa ccattaccag cttctaaagt cttagtccaa ctggaaaaag aaaatttgtc
     9301 cattgacgac cgagttttgg ttcaaaaact acaactaact gtccgtgggc aagaaaaaat
     9361 cggtattatc gggccaaatg gtgttgggaa atcaactctg ttagccaaat taaagcaact
     9421 tctgaatgat aaaagagaga tttcccttgg ttttatgcca caagattacc acaaaaaact
     9481 gcaattggat ttatcaccaa tagcctacct cagcaaaact ggggaaaaag aggaactaca
     9541 gaaaatccaa tctcacctag ctagtctcaa tttcagttat ccagaaatgc agcatcaaat
     9601 tcgctcctta tctggcggac aacagggaaa actcctgctt ttggatttag tcctgcgcaa
     9661 accaaacttt ctcctgctgg atgaacccac acgaaacttt tctcccactt ctcaacccca
     9721 aatcagaaaa ctctttgcaa cctatccagg cggtctcatc actgtttcgc atgaccgtcg
     9781 tttcttaaaa gaggtctgtt caagcatcta ccgcttgaca gaacacggtt tggagttagt
     9841 taatttagaa gatgtataaa tttgcaacat agcaaaaatc cagagacgac ctctggattc
     9901 ttttacatct gttttaaacg ttcaatccgt tctgagatag gtgggtgggt ataaaagagt
     9961 ttttggaacc ccccaccttt cttgggatca ttgatataaa gagcactgct agcatcatcg
    10021 acgtggcgac tcataggttt gctattgtcc aacttatcta gggcattaat cattccctga
    10081 ggattgcgag tcagctcgac actagatgca tctgccagaa attccctctg acgagaaata
    10141 gcgagctgaa ccaaggttgc agcgagaggt gccagtacaa tagctagtag ggaaaccact
    10201 agcataatga tttcaagacc atttccatct cggtcatcat cacttcgtct gcgacctgct
    10261 ccaccccacc acatcatacg acctgccata ccagaaagca tggtgatagc actaacaagg
    10321 gcaactgcaa tagtcgaaat acggatatca taattacgaa tatgactgac ttcatgtccc
    10381 ataacagctt ctagttcttc acgattcatg atagctagta gacctgaagt cgcagcaaca
    10441 gccgcatttt gaggattaga acctgtcgca aaggcattta aggctggatc atcaatgatg
    10501 aaaacacggg gcataggaat ctgagcgacc agagccatat cttccactac atggtagagg
    10561 tctggtgccg tttgctcatc cacctcacac gctccattca tggacatgac aatctctgtc
    10621 gattgaaaaa tcatagacaa agcgtagata aagccgataa tcagtgcgat aaccaaacca
    10681 ccaagtccag atcttataaa gagataacca accgcataac caacaagagc taagagtagg
    10741 aaaaatacca gcaacaaaat ccaggttttt cgtttattgc ttgcaatttg atcaaacaac
    10801 atcttagtca cctaaaccgc taaaatcaac tttaggaacc gacttttcct cttcaggtgt
    10861 ttgaaggaaa tctgccgctt taaatccaaa cattccagcg ataatattgc tcgggaaagt
    10921 ttctaatttt acattgtagt tgctgacaac actgttatag agttgacgag agtaagaaat
    10981 tttattttct gtgtttgtca actcctcttg caatttaaca aagttagcac tagctttcaa
    11041 atctggatag ctttctgcaa ctgcaaaaat acctgaaacc tgacgagtga gggcatcact
    11101 ggctttcata gcttctgctg gtgaagtcgc tgccgccact tggttacgta gttctgccac
    11161 cttttcaagg gtagaacctt catatttggc ataacctttt acagtctcaa tcaagtttgg
    11221 caagagatca ttgcgacgtt tcaactgaac atcaatctga ctccaagcct ccttggtttg
    11281 catacgattt ttaaccaaac cgttatagct aacaatcaca aaaataacaa caagagctaa
    11341 aactccaaga ataatccaag tcataatata agtcctttct gcttttagat tagtaccagt
    11401 atatcaaatt ttctatgatt gtggtaaaat aagatgatac taaagaagga aataactatg
    11461 aaaccaaaaa cattttacaa cttgcttgcc gagcagaatc ttccactttc ggaccagcaa
    11521 aaagaacaat ttgaacgtta ttttgagctc ttggtcgagt ggaatgagaa gattaatttg
    11581 acggcgatta cggacaagga agaagtttat ctcaaacatt tttacgattc gattgcaccc
    11641 attcttcaag gtttgattcc caatgaaact atcaaacttc ttgatatcgg ggctggggca
    11701 ggatttccta gtctaccaat gaaaattctc tatccggagt tagatgtgac cattattgat
    11761 tcactcaata agcgcatcaa cttcctacaa ctcttggctc aagaactgga tttgaacgga
    11821 gttcatttct accacggacg tgccgaagat tttgcccaag acaagaactt ccgtgctcaa
    11881 tatgattttg taacagctcg tgcggttgcc cgtatgcagg tcctatctga attgactatt
    11941 ccctacctta aggttggtgg aaaactattg gcactcaagg ccagcaatgc gcctgaggag
    12001 ttgttagaag ctaagaatgc cctcaatctc ctttttagta aagtcgaaga caatctcagc
    12061 tacgccctac caaatagaga tccgcgttac atcacagtgg tagaaaagaa aaaagaaaca
    12121 ccaaataaat atccacgtaa ggctggtatg ccaaataaac gcccgcttta aatttttaag
    12181 taaaaaaata tttacaaaat caacctcgct ctcttatttt taggctcggg aaaaaatgat
    12241 ttacaaaatc agcctcgctc ttttatttct aggctcggga aaaaatgatt tacaaaatca
    12301 gcctcgctct tttatttcta ggctcgggaa aaaatgattt acaaaatcat ttttttctgc
    12361 tatactatcc taagcaaagg tttttaatgt catcccgtga ggtgacgaag acgcagaaat
    12421 atttaaaact ctttaaaatc taaattttaa agaagtctta ctctgagggc ctattgctgt
    12481 aaaataatgg gctctttttt gatgcccaaa agtgaggttt atatgaaaca agaatcaact
    12541 gttgatttgt tactagacgt tgaccaacgt ccttcggatg gaaaaggaat tctccttagt
    12601 ttccaacacg ttttcgccat gtttggtgcg accatcttgg taccattgat tttgggaatg
    12661 cctgtatctg ttgccctttt tgcttcaggt gttggaacac tcatctacat gattgctact
    12721 ggttttaaag ttccagttta tctaggttct tcatttgcct ttatcacagc tatgtcactg
    12781 gctatgaaag aaatgggggg ggatgtatct gctgcccaaa caggggttat cttgactggt
    12841 ttggtctatg tccttgttgc taccagcatc cgatttgtag gaacaaaatg gattgataaa
    12901 ctcttgccac caatcattat cggtcctatg atcatcgtta tcggtcttgg acttgcaggt
    12961 tcagctgtta ccaatgcagg tcttgtagca gacggaaatt ggaaaaatgc tctggtagcc
    13021 gttgttactt tcctaattgc tgcctttatc aatacaaaag gaaaaggctt cctacgaatc
    13081 attccattcc tctttgccat tatcggtggt taccttttcg cactaactct tggcttggtt
    13141 gactttacac cagttcttaa agccaactgg ttcgaaattc ctggtttcta cttgccattt
    13201 agcacaggtg gtgcctttaa agagtacaat ctttactttg gtccagaagc catcgctatc
    13261 ttgccaatcg ctatcgtaac aatttctgaa catatcggag accatactgt tttgggtcaa
    13321 atctgtggtc gtcaattctt aaaagaacca ggtcttcacc gtactcttct tggtgacggt
    13381 atcgcaactt ctgtttctgc cttccttggt ggaccagcca atacaactta cggagaaaat
    13441 acaggggtta tcggtatgac tcgtatcgct tctgtctcag ttatccgtaa cgctgccttc
    13501 atcgcgattg ccctcagctt ccttggtaaa ttcactgcct tgatttcaac tattccaaac
    13561 gctgtacttg gtggtatgtc aatccttctc tatggggtta tcgccagcaa tggtttgaaa
    13621 gtcttgatta aagaacgtgt tgatttcgct caaatgcgaa acctcatcat cgcaagtgct
    13681 atgttggttc ttggacttgg aggagctatc cttaaacttg gtccagttac actttcaggt
    13741 actgcccttt cagccatgac aggaatcatc ttgaacttga tcttgccata cgaaaataaa
    13801 gactaagagt ctaaatacac ctaatccact cagacagctg agtggatttt tcgtatatta
    13861 taataaaagt gtcttaacaa aattattaaa atcaaaaaac gtataatatc agatattcta
    13921 aaaccttgat actgtacgtt ttatcataga aatttttact ttattttctc atcaaatgag
    13981 atttgcatca atctcttgtc ttacttgcgt ttcttcttcg ctttcttcat tttgttagcc
    14041 atacgtttca tggactgttt catggcaaat tcaccaattt tacctttcaa accgccacca
    14101 aacatctggc tcatatctgg cattcctgct cctccgagag ctgataagtc aggcataccg
    14161 ccttgtccca tcattccttc aagggcagac atatccattc ctcccatatt tggcatattt
    14221 ttaggaaggt tatttggatt aatccccatt tgcttcatca ttttattcat atccccagac
    14281 ataacaccct gcatgagctg tttagcctgg ttaaagtcct tgatgaattt attgacttcg
    14341 acgaatgtat ttccagaacc agcagcaata cgacggcgac ggcttggatt taacaaatct
    14401 gggttttcac gttcttcagg tgtcatcgaa gacacaatgg cacgtttacg agcaatctgg
    14461 cgttcatcca ccttcatgtt ttgaagtgct ggattgttgg ccatacctgg aatcatcttg
    14521 agcaagtctt ccatcggccc catattttgc acctgatcta attgatcgat gaaatcatta
    14581 aaatcaaagg tgttttcgcg catcttctca gccatttcaa gggctttttg ttcatcgtat
    14641 tcctgagaag ctttctcaat caaagtgagc atatccccca tgccaaggat acggctagac
    14701 atgcggtctg ggtggaaggt ttcaatgtcc gtaatctttt cacctgtacc agtgaacttg
    14761 attggttttc cagtaatgtg acgaacagac agagcagcac caccacgagt atcgccatca
    14821 atcttggtaa ggatgacccc agtcacttcc aactgagcat taaactcacg cgcaacattg
    14881 gctgcttcct gaccaatcat agcatcaacg acaagcaaga tttcatttgg ttgagccaat
    14941 gctttcacat cacgaagctc attcatgagg agctcatcaa tctgcaaacg acccgcagta
    15001 tcaatcaaga catagtcgtt atgattagtt tgggcttgct ccaaaccttg acgtacaatc
    15061 tcaacagctg gtacttctgt tccaagtgca aagacaggca catcaatctg ttgtcccaag
    15121 gtcttaagct ggtcaatggc agctggacga taaatatccg ccgcaatcat caaaggacga
    15181 gcattttctt ctttcttgag tttgttggcc aatttaccag caaaggttgt tttaccagcc
    15241 ccttgtaaac caaccatcat gatgatggtt ggaatcttag gtgacttgat aatttctgcc
    15301 gtatcagaac ctaaaacggc tgtcagttcc tcatcaacga ttttaataat ctgttgcgca
    15361 ggattaagtg tatcaatgac ctcatgcccg actgcacgct cacgaacttt cttgataaag
    15421 tcctttacaa caggcaaggc aacgtcggcc tcgagcaagg ccaagcgaat ttctttggtt
    15481 gcctcttgga catcagattc agagattttt ccttttttac gtagattttt aaagacgttc
    15541 tgcaaacgtt ctgttaaact ttcaaatgcc atttttcttc ctcttattct ctattatcaa
    15601 tgcttgttaa aatttctatc tgctcctgca gaaagttatc cttgggatag cgctccaaaa
    15661 tctgatcaaa aatctgactg cggacaatat agtccgagta catgtgcaat ttcatctcat
    15721 aatcttccag aatcttttct gttcgcttga tattgtcata gacagcctga cgactgacac
    15781 cgaactcctc ggcaatttca gcaaggctgt aatcatcagc gtagtagagc tcgatataat
    15841 tcatttgctt atctgtcaaa agcgccgcat aaaattcaaa gagcgcattc atacgattgg
    15901 ttttttcgat ttccataact tttattatac caaaaattag cctaatctac cacactagga
    15961 agccgatcca agaagataga tagctaaatt tgaaaaagac atgagcctag ccccaagtaa
    16021 tttccaattg atagctggca aagggatgtc cctcttgatt ttgtagttga taatctagtt
    16081 caatcttttg cctatcaact tgataatggc tcgtttggat ggtaaactcc tgcataccca
    16141 taggtgtggg aatataggct aaactatcac tatcctttag aaagcgcata atggtcttgg
    16201 gattggaaaa tcgactcatc acaagttctt gaccatgaaa tttaatcact actttttcct
    16261 tttcctcatt atagaaaagc aggtagctat aatctccttt ttcatgcact tccacatcat
    16321 aaagctggtc aatcacttcc aactgctcat caaactgaat tgtatttcgc atccgaatct
    16381 tcacatcagg ccctctttct tgtctcttgt cctactattt taccaaaaag agcaggattt
    16441 tgctataatg gtcatatgaa cgaaaaagta ttccgtgacc ctgttcacaa ctacatccat
    16501 gtcaataatc aaatcatcta tgacttgatt aatacaaaag aatttcagcg tttgcgccgg
    16561 atcaaacaac tgggaacttc cagttatacc ttccacggtg gagaacacag tcgcttctct
    16621 cactgtctag gagtctatga aattgcacga cgcatcacag agattttcga agaaaaatat
    16681 cctgaggaat ggaatcctgc cgagtctctc ttgaccatga ccgctgctct cctacacgac
    16741 cttgggcatg gtgcctactc ccatactttt gaaaatctct ttgatacaga ccatgaagcc
    16801 attactcagg agattattca aaatcctgag acagagattc accaagtcct gctacaagtg
    16861 gcacctgatt tcccagaaaa ggtggccagt gtcattgacc atacctatcc taataagcag
    16921 gtcgtgcagc tcatttctag tcagattgac gcagatcgca tggactatct cttgcgcgac
    16981 tcctatttta caggagcatc ctatggggaa tttgacctga ctcgaatcct ccgagtcatt
    17041 cgtcctatcg aaaatggtat cgcctttcag cgcaatggca tgcacgccat cgaagactac
    17101 gtcctcagtc gctaccagat gtacatgcag gtttatttcc accccgcaac acgcgccatg
    17161 gaagttctcc tacagaatct tctcaaacgc gccaaggaac tctatcctga ggacaaggat
    17221 ttctttgccc gaacttctcc acacctcctg cctttcttcg aaaaaaatgt gaccttgact
    17281 gactatctgg ctctggatga tggcgtgatg aatacctact tccagctttg gatgaccagt
    17341 cctgacaaga ttcttgcaga tttatcgcaa cgctttgtca accgcaaggt ctttaaatcc
    17401 attagctttt cgcaagagga tcaagaccaa ctcgccagca tgagaaaatt agctgaggat
    17461 atcggctttg atcccgacta ctacactgcc attcataaga actttgacct cccttatgat
    17521 atctatcgtc ccgaatctga aaacccacgg acacagattg agattttaca aaaaaatgga
    17581 gaactggcag aactctctag cctgtcccct atcgtccaat cccttgctgg aagtcgccac
    17641 ggagataatc gcttttattt cccgaaagaa atgttagacc aaaacagcat cttcgcaagc
    17701 atcacccagc aatttttaca cttgattgag aacgatcatt ttaccccaaa taaaaactaa
    17761 aagaggaaat ttatgagtat taaactaatc gccgtcgata ttgacggaac cctagtcaac
    17821 agccaaaagg aaatcactcc tgaagtcttt tctgccatcc aagatgccaa agaagctggt
    17881 gtcaaagtcg tgattgcaac tggccgcccc atcgcaggtg ttgccaaact tctggacgac
    17941 ttgcagttga gagaccaagg tgactatgtg gtgaccttca atggtgccct tgtccaagaa
    18001 actgctactg gccatgagat tatcagcgaa tccttgacct atgaggatta tctggatatg
    18061 gaattcctca gtcgcaagct cggtgtccac atgcatgcca ttaccaagga cggtatctat
    18121 actgcaaatc gcaatatcgg aaaatacact gtacacgaat caaccctcgt cagcatgcct
    18181 atcttctacc gtacccctga agaaatggct ggcaaggaaa ttgtcaagtg tatgttcatc
    18241 gatgaaccag aaatcctcga tgctgcgatt gaaaaaatac cagccgaatt ttacgagcac
    18301 tactctatca acaaatctgc tcctttctac ctcgaactcc ttaaaaagaa tgtagacaag
    18361 ggttcagcta ttactcactt agctgaaaaa ctaggattga ccaaagatga aaccatggca
    18421 atcggtgacg aagaaaatga ccgtgccatg ctggaagtcg ttggaaaccc cgttgtcatg
    18481 gaaaatggaa atccagaaat caaaaaaatc gccaaataca tcactaaaac aaatgacgaa
    18541 tccggcgttg cccacgccat ccgaacatgg gtactgtaaa agtatcattt ttcaataaga
    18601 attgattagc aataaaatcc aatgaatttt tttagcaaac tatttaattt aaaacaaaat
    18661 aatcataata gagacacaaa ttctgattgt aacaattttt acctaaacga attagaatgt
    18721 ggccttactc ctgggcaact catactcata gattggactc aaaaaacagg gagaaattat
    18781 aatttcccaa gatattttaa atactctctt caaattgacc ctgaatctac acacaatcaa
    18841 ttatacaaat taggatactt cactaaaaat aagactttat catatcttac agtagtagaa
    18901 ttaaaaacta tattatctaa acataattta gctacttctg gaaaaaaagc agaattaatt
    18961 acaagaataa ttaataatgt taacattgac aatttagata ttccgttcga atttaaacta
    19021 acaaaagaag cacaaaatct tattatcgaa catagtgact atatcaaagc atactatgat
    19081 aaagacataa ctatggaaga ttattgtaaa gaaaaaaaca atatctcttt taaagcaact
    19141 tttggtgata taaaatggag tctcttaaat aaacaagctc ataggaatac tgtatcagga
    19201 gattttggat gcttatctaa cacacgaaag gctcagggaa gacatttgga acaagaaggt
    19261 aatattaaac atgctttaat atattacata gaatctttga taattactat ttcaggatta
    19321 gaaaacaatt tttcagccac tgattatcca gtatattatc ccgattcgat acctgactac
    19381 tcactaaaac atattcaaac attaatggaa tcattatctg atgacgatta tgattttgct
    19441 tttgatgaag cattatttcg cttctcaatt ttgaatgcaa atcatttttt atctaaggaa
    19501 gatattgact atttaagagt taatttacct cgttccactg ctgaagaaat aaacaattac
    19561 ttaaagaaat atgaatgtta tagtccttta aataatttag aacttgacga ttttgaataa
    19621 attgactata caaacattta tatactcgat atagtctcaa ttttatctga tgattgccca
    19681 aatttttcaa taataaaacg cataatatta tggagacaat cccctatatt atgcgttctt
    19741 ttaatatcaa agactttttg acaaacttct ttgatatcta attacatgcc ccctgcagga
    19801 atcgaacctg caactactcc ttaggaggga gttgttatat ccattgaact aagggagcta
    19861 gataaaaact ctgctgaaaa gcagagtttt ttagtcgaat taacgacgga tttctttgat
    19921 acgagctgcc ttaccttgaa gagcacgcaa gtagtacaat ttcgcacgac gtactttacc
    19981 gtaacgtaca acttcgattt tttcaacacg tggagtgtgg attgggaaga tacgctcaac
    20041 acctacaccg ttagagattt tacgaactgt gtagttttca gagatgccag cacctttacg
    20101 tgcaataaca acaccttcaa aaatctggat acgttcacgg ttaccttcga caactttcgc
    20161 atgtacacga acagtgtcac caggacggaa tgatgggata tctgtacgaa gttgaccttc
    20221 agtcaagctt tggattaatg gattcatttt attctcctat ctttgtcaat cttgaggaat
    20281 cttcctcagc ggataaactg tatttttgtg cgtccattac acacaagata tagtttacca
    20341 aatttctaaa aaaaagtaaa gaaatttata gcaaaattcc taaaaaaatc gcaaccaaac
    20401 cacctatgta agtcaaagtc aggtaagaat aaaagacctt cttatcactt agcagtcttt
    20461 gaagttcgtc attcaaggtc gaaaaagttg ttaaaccgcc acaaaatcct gttgctagaa
    20521 tagcatatac ttccttagac tctacatgat tgtagaatac tccaattaaa aaacaaccta
    20581 aaagattagc tatgagcgtt ccgagtggca atttagaagc ttgattatag cgagaaaaga
    20641 aataccgtac gagtgctccc aagccacagg cgattgcaag atagacgatt accatttctt
    20701 cctccccaaa tagtaagcta aaagcaggcc tccaccgata ctcaaaagca aatacagtat
    20761 caaactaaga taacgccctg tatcaagcag cttcacagta tcaagcatta ggctggaaaa
    20821 agttgttaaa cctccgcaaa aacccgtccc cagtgctaaa atcaagccct tactagtccc
    20881 cttatagacc agatagccct tgacaagata aatcaagcag aaaattccca gatagttgac
    20941 aaagagagtg ccccaaggga aatctggact ggctggtaac caagtggaaa ctaggtagcg
    21001 gacaagtccg cccaacatag cagctagaaa aatccctagc ggataaaatt gttctttttt
    21061 catttgatat tttgatcctg ataatcacgc gaacgtttga gtatgtccga aaaagtcgcg
    21121 acaatagtct cctgatagcg cttgtcctct acacgacttc taaccttttc aaaaataact
    21181 gcttctctct tagtatctaa aatcggtttc cctgaagcct tcttataagc gacaactcct
    21241 tcaactaagt gcattcgttc ttctaacagt ttgacaattt ggtcgtcgat ttgatcgatt
    21301 tcttgacgaa taatatctaa atccatacag tctcctcctt tatttgaatt attgtatcaa
    21361 aaagccatca attaggctag taaaatccca actctcgata agaaaaatgc actgattgat
    21421 tacatcagcg cacttttatg cttatcctac tttagcaacc aattcttctg cgaattgttc
    21481 caagcgttca atatcttctt cctcggcaga aagatcaact ttaacacact ctgaaccttt
    21541 ttctgctcct gttgacacaa agacacggtc aaagtcatca acagccttac agaattcatc
    21601 gtagaaggta tctcctgagc cgaccactcc gtagattttg ccattcaagt tgagatctgc
    21661 taggtcttcg tagaagtcca tcatctcatc tggcaattca ccatcaccat aagtataggt
    21721 cgcaacgata gcgatgtctg cttccaagaa gtctgaagcg tcaacagttg tacattcatc
    21781 aacatcaaca tccaagccca agtcacgtaa tttgtctgct acaatatctg caatttcttc
    21841 ggtattaccg gtcatactgg caaatacaat ttttgctaat gccatatcgt cctcctcaat
    21901 ttatctttct ccattatatc acatcttttt cattttaaaa ataaaaattc ttgtgctaca
    21961 atgaaatgag aaagaattga ggttatttat ggagatttgc caacaaattt tagaaaaaat
    22021 taaagaatac gacaccatta tcattcatcg tcatatgaaa ccagaccctg atgccttggg
    22081 aagtcaggtg ggattgaaag ccttgctgga acatcatttc ccagaaaaaa ccatcaaagc
    22141 cgtcggtttt gatgaaccaa ctcttacttg gatggctgag atggatcttg ttgaagatag
    22201 agcctaccaa ggcgcacttg tcatcgtctg tgatacagct aatactgctc gtatcgatga
    22261 taagcgctat agtcaaggtg attttctcat taagattgac caccatccaa atgatgatgt
    22321 atacggtgac ctgtcttggg tcgatactag ttcaagtagc gctagcgaga tgattaccct
    22381 atttgcccaa acaacccaac tagccttggc agatcgcgat gctgagttgc tctttgcagg
    22441 aattgtcggt gatacaggtc gcttcctcta cccttctacc actgcacgga ctcttcgtct
    22501 ggctgcttat ttgagagaac ataactttga ctttgcggct ctcactcgca aaatggacac
    22561 tatgagctac aaaattgcta aactgcaagg ctacatctac gaccatctgg aagtggatga
    22621 aaatggtgct gctcgcgtta tcctgagtca agaagtcttg aaacaataca atgtaaccga
    22681 tgctgaaact gcagccattg tcggtgcacc tggacgcatt gacagagtga gtctctgggg
    22741 aatttttgtc gaacaggctg atggccacta ccgagttcgc ttacgcagta aagtccatcc
    22801 tatcaatgaa attgccaagg agcatgatgg tggaggccac cctctagcaa gtggtgctaa
    22861 ttcctatagc ctagaagaaa acgaaatcat ctaccaaaag ttaaaaaact tgcttaaaaa
    22921 ctgataaaat acttgccaaa cttttcagaa tctgatagac tagtatggta acaatctatg
    22981 gctcgcaaag agaccatggc agaaaggaaa tattgcaaaa tgaaaaaaga tatccatcca
    23041 gaatatcgcc cagttgtctt catggacaca actactggtt accaattcct tagcggttca
    23101 acaaaacgct ctaacgaaac agttgagttc gaaggcgaaa cttacccatt gatccgtgtg
    23161 gaaatttcat cagactcaca cccattctac actggacgtc aaaagttcac tcaagcagat
    23221 ggacgcgtgg atcgtttcaa caaaaaatac ggtctcaaat aatgataaga gaacagtttc
    23281 ggctgttctt ttttgtttct tgaaatcaac tgctgttttc atgttccaga ctcatctgta
    23341 ggttcggttt ccatgctact aggcaggaag gaaatagctg tttcaacacg tccataatga
    23401 gctgtactat tgtcacgaac cacactttca ttgatggtcc aagtggaatt cattttctta
    23461 aaagcttctc ggactttttc caaatctttg gaggcaatgg cctgctctaa ggtttcaaaa
    23521 cgaggactta gacggtttac caatttttcc ttttccgcat ctaggtcaac aggattttgt
    23581 tctttttcaa aagctaatag agctgaggaa atttcggtga gtttggcttc agtaatatct
    23641 ccagatagag ctaacttttc cttaacaatc ttaccaacct cagaatcctt attttctact
    23701 ctttcgaagt ctgatgccat cttcgtaacg agtttctgga cctcagcctg atcaccattt
    23761 ttaaccgctt tggatgcatc tgtgattttt acgaaataag aactcaagct ttcttgggca
    23821 cctgctgggg
//
LOCUS       DAVLXH010000031        23765 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00028199
            SAMN33607166-rid17955573.denovo.031, whole genome shotgun sequence.
ACCESSION   DAVLXH010000031 DAVLXH010000000
VERSION     DAVLXH010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607166
            Sequence Read Archive: SRR23725544
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 23765)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23765)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721421.1
            Genome Coverage       :: 115x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:42:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,210
            CDSs (total)                      :: 2,161
            Genes (coding)                    :: 2,023
            CDSs (with protein)               :: 2,023
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 73 of 138
            Pseudo Genes (incomplete)         :: 60 of 138
            Pseudo Genes (internal stop)      :: 40 of 138
            Pseudo Genes (multiple problems)  :: 31 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23765
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607166-rid17955573.denovo.031"
                     /strain="AUSMDU00028199"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1349"
     gene            186..344
                     /locus_tag="VYO11_001336"
     CDS             186..344
                     /locus_tag="VYO11_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin class II family protein"
                     /protein_id="HEV1595901.1"
                     /translation="MNTKKMSQFEIMDTEMLACVEGGGCNWGDFAKAGVGGGAILGGV
                     AYAATCWW"
     gene            1063..3216
                     /locus_tag="VYO11_001337"
     CDS             1063..3216
                     /locus_tag="VYO11_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000668284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
                     /protein_id="HEV1595902.1"
                     /translation="MKFGKRHYRPQVDQMDCGVASLAMVFGYYGSYYFLAHLRELAKT
                     TMDGTTALGLVKVAEEIGFETRAIKADMTLFDLPDLTFPFVAHVLKEGKLLHYYVVTG
                     QDKDSIHIADPDPGVKLTKLPRERFEEEWTGVTLFMAPSPDYKPHKDQKNGLLSFIPI
                     LVKQRGLIANIVLATLLVTLINIVGSYYLQSIIDTYVPDQMRSTLGIISIGLVIVYIL
                     QQILSYAQEYLLLVLGQRLSIDVILSYIKHVFHLPMSFFATRRTGEIVSRFTDANSII
                     DALASTILSIFLDVSTVVIISLVLFSQNTNLFFMTLLALPIYTVIIFAFMKPFEKMNR
                     DTMEANAALSSSIIEDINGIETIKSLTSESQRYQKIDKEFVDYLKKSFTYSRAESQQK
                     ALKKVAHLLLNVGILWMGAVLVMDGKMSLGQLITYNTLLVYFTNPLENIINLQTKLQT
                     AQVANNRLNEVYLVASEFEEKKTVEDLSLMKGEMTFKQVHYKYGYGRDVLSDINLTVP
                     QGSKVAFVGISGSGKTTLAKMMVNFYDPSQGEISLGGVNLNQIDKKALRQYINYLPQQ
                     PYVFNGTILENLLLGAKEGTTQEDILRAVELAEIREDIERMPLNYQTELTSDGAGISG
                     GQRQRIALARALLTDAPVLILDEATSSLDILTEKRIVDNLMALDKTLIFIAHRLTIAE
                     RTEKVVVLDQGKIVEEGKHADLLAQGGFYAHLVNS"
     gene            3229..4578
                     /locus_tag="VYO11_001338"
     CDS             3229..4578
                     /locus_tag="VYO11_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family secretion protein"
                     /protein_id="HEV1595903.1"
                     /translation="MKPEFLESAEFYNRRYHNFSSSVIVPMALLLVFLLGFATVAEKE
                     MSLSTRATVEPSRILANIQSTSNNRILVNHLEENKLVKKGDLLVQYQEGAEGVQAESY
                     ASQLDMLKDQKKQLEYLQKSLQEGENHFPEEDKFGYQATFRDYISQAGSLRASTSQQN
                     ETIASQNAAASQTQAEIGNLISQTEAKIRDYQTVKSAIETGASLAGQNLAYSLYQSYK
                     SQGEENPQTKVQAVAQVEAQISQLESSLATYRVQYAGSGTQQAYASGLSSQLESLKSQ
                     HLAKVGQELTLLAQKILEAESGKKVQGNLLDKGKITASEDGVLHLNPETSDSSMVAEG
                     ALLAQLYPSLEREGKAKLTAYLSSKDVARIKVGDSVRYTTTHDAGNQLFLDSTITSID
                     ATATKTEKGNFFKIEAEINLTSEQAEKLRYGVEGRLQMITGKKSYLRYYLDQFLNKE"
     gene            4748..5455
                     /locus_tag="VYO11_001339"
     CDS             4748..5455
                     /locus_tag="VYO11_001339"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HEV1595904.1"
                     /translation="MSKQLIYSGKAKDIYTTEDENLIISTYKDQATAFNGVKKEQIAG
                     KGVLNNQISSFIFEKLNAAGVATHFVEKLSDTEQLNKKVKIIPLEVVLRNYTAGSFSK
                     RFGVDEGIALETPIVEFYYKNDDLDDPFINDEHVKFLQIADDQQIAYLKEETRRINEL
                     LKVWFAEIGLKLIDFKLEFGFDKDGKIILADEFSPDNCRLWDADGNHMDKDVFRRGLG
                     ELTDVYEIVWEKLQELK"
     gene            5657..9382
                     /locus_tag="VYO11_001340"
     CDS             5657..9382
                     /locus_tag="VYO11_001340"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HEV1595905.1"
                     /translation="MDKRIFVEKKADFQVKSESLVRELQHNLGLSSLKSIRIVQVYDV
                     FDLAEDLFAPAEKHIFSEQVTDHVLDEVSVQADLANYAFFAIESLPGQFDQRAASSQE
                     ALLLLGSSSDVTVNTAQLYLVNKDIDATELEAVKNYLLNPVDSRFKDITTGIAKQEFS
                     ESDKTIPKLTFFESYTAEDFARYKAEQGMAMEVDDLLFIQDYFKSIGRVPTETELKVL
                     DTYWSDHCRHTTFETELKHIDFSASKFQKQLQSTYDKYIAMREELGRSEKPQTLMDMA
                     TIFGRYERANGRLDDMEVSDEINACSVEIEVDVDGVKEPWLLMFKNETHNHPTEIEPF
                     GGAATCIGGAIRDPLSGRSYVYQAMRISGAGDITAPISETRAGKLPQQVISKTAAHGY
                     SSYGNQIGLATTYVREYFHPGFVAKRMELGAVVGAAPKGNVVREKPEAGDVIILLGGK
                     TGRDGVGGATGSSKVQTVESVETAGAEVQKGNAIEERKIQRLFRNGNVTRLIKKSNDF
                     GAGGVCVAIGELADGLEIDLNKVPLKYQGLNGTEIAISESQERMAVVVRPEDVDTFVA
                     ECNKENIDAVVVATVTEKPNLVMHWNGETIVDLERRFLDTNGVRVVVDAKVVDKDVKL
                     PEERQTSAETLESDTLTVLSDLNHASQKGLQTIFDCSVGRSTVNHPLGGRYQLTPTEA
                     SVQKLPVQHGVTHTASVIAQGFNPYVAEWSPYHGAAYAVIEATARLVAAGANWSKARF
                     SYQEYFERMDKQAERFGQPVAALLGSIEAQIQLGLPSIGGKDSMSGTFEELTVPPTLA
                     AFGVTTADSRKVLSPEFKAVGENIYYIPGQALSAEIDFDLIKKNFTQFEAIQADHKVT
                     SASAVKYGGVVESLALATFGNYIGAEVTLPELKTALTAQLGGFVFTSPEEIAGVEKVG
                     QTKADFTLTVNRVKLDGHKLDSAFQGTLEEVYPTEFTRAKELEEVPAVASDVVIKAKE
                     KVEKPVVYIPVFPGTNSEYDSAKAFEKEGAEVNLVPFVTLNEEAIVKSVETMVDNIDK
                     TNILFFAGGFSAADEPDGSAKFIVNILLNEKVRVAIDSFIARGGLIIGICNGFQALVK
                     SGLLPYGNFEAANSTSPTLFYNDANQHVAKMVETRIANTNSPWLAGVQVGDIHAIPVS
                     HGEGKFVVTAEEFAELRDNGQIFSQYVDFNGKPSMDSKYNPNGSVHAIEGITSKNGQI
                     IGKMGHSERYEDGLFQNIPGNKDQHLFASAVKHFTGK"
     gene            9475..10917
                     /locus_tag="VYO11_001341"
     CDS             9475..10917
                     /locus_tag="VYO11_001341"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HEV1595906.1"
                     /translation="MTYEVKSLNEECGVFGIWGHPDAAKLTYFGLHSLQHRGQEGAGI
                     LSNDQGQLKRHRDMGLLSEVFRNPANLDKLTGAGAIGHVRYATAGEASVDNIQPFLFR
                     FHDMQFGLAHNGNLTNAASLKKELEQRGAIFSATSDSEILAHLIRRSHNPSLMGKIKE
                     ALSLVKGGFAYILLFEDKLIAALDPNGFRPLSIGKMANGAVVVSSETCAFEVIGAEWI
                     CDLKPGEIVIIDDEGIQYDSYTDDTQLAICSMEYIYFARPDSNIHGVNVHTARKRMGA
                     QLAREFKHEADIVVGVPNSSLSAAMGFAEESGLPNEMGLIKNQYTQRTFIQPTQELRE
                     QGVRMKLSAVSGVVKGKRVVMVDDSIVRGTTSRRIVQLLKEAGATEVHVAIGSPALAY
                     PCFYGIDIQTRQELIAANHTVEETRQIIGADSLTYLSIDGLIESIGIETDAPNGGLCV
                     AYFDGDYPTPLYDYEEDYRRSLEEKTSFYK"
     gene            10954..11976
                     /locus_tag="VYO11_001342"
     CDS             10954..11976
                     /locus_tag="VYO11_001342"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HEV1595907.1"
                     /translation="MTNKNAYAQSGVDVEAGYEVVERIKKHVARTERAGVMGALGGFG
                     GMFDLSKTGVKEPVLISGTDGVGTKLMLAIKYDKHDTIGQDCVAMCVNDIIAAGAEPL
                     YFLDYVATGKNEPAKLEQVVAGVAEGCVQAGAALIGGETAEMPGMYGEDDYDLAGFAV
                     GVAEKSQIIDGSKVVEGDVLLGLASSGIHSNGYSLVRRVFADYTGEEVLPELEGKKLK
                     EVLLEPTRIYVKAVLPLIKEELVNGIAHITGGGFIENVPRMFADDLAAEIDESKVPVL
                     PIFKALEKYGQIKHEEMFEIFNMGVGLMLAVSPENVERVKELLDEAVYEIGRIVKKEN
                     ESVIIK"
     gene            11973..12518
                     /gene="purN"
                     /locus_tag="VYO11_001343"
     CDS             11973..12518
                     /gene="purN"
                     /locus_tag="VYO11_001343"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HEV1595908.1"
                     /translation="MKKIAVFASGNGSNFQVIAEEFPVEFVFSDHRDAYVLERAKQLG
                     VLSYAFELKEFESKADYEAALVELLEEHQIDLVCLAGYMKIVGPTLLSAYEGRIVNIH
                     PAYLPEFPGAHGIEDAWNAGVGQSGVTIHWVDSGVDTGQVIKQVRVPRLADDTIDRFE
                     ARIHEAEYRLYPEVVKALFTD"
     gene            12602..13111
                     /locus_tag="VYO11_001344"
     CDS             12602..13111
                     /locus_tag="VYO11_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000894002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HEV1595909.1"
                     /translation="MLESKKTTRYVFYVYLMLLTWGILFKFETNPEFIAFFLAPRYIN
                     WIPFSEPLIVDGKIVFAEMLFNLIFFIPLGVCFPLIKTNLSSLRIVGTGFLISLLFEC
                     LQYILAIGITDITDLTLNTLGVCVGLLIYQIFIRVFKSQTRKWINILGMLSLGFAYLV
                     LLLLHLIGV"
     gene            13136..14683
                     /gene="purH"
                     /locus_tag="VYO11_001345"
     CDS             13136..14683
                     /gene="purH"
                     /locus_tag="VYO11_001345"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006146083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HEV1595910.1"
                     /translation="MTKRVLISVSDKAGIVEFAQELKKLGWEIISTGGTKVALDNAGV
                     DTIAIDDVTGFPEMMDGRVKTLHPNIHGGLLARRDLDSHLEAAKDNKIELIDLVVVNL
                     YPFKETILKPDVTYADAVENIDIGGPSMLRSAAKNHASVTVVVDPADYAVVLDELAAN
                     GETSYETRQRLAAKVFRHTAAYDALIAEYFTAQVGESKPEKLTLTYDLKQPMRYGENP
                     QQDADFYQKALPTDYSIASAKQLNGKELSFNNIRDADAAIRIIRDFKDSPTVVALKHM
                     NPCGIGQADDIETAWDYAYESDPVSIFGGIVVLNREVDAATAEKMHGVFLEIIIAPSY
                     TDEALAILINKKKNLRILALPFNAQEASEVEAEYTGVVGGLLVQNQDVVKESPADWQV
                     VTKRQPTETEATALEFAWKAIKYVKSNGIIVTNDHMTLGVGPGQTNRVASVRLAIDQA
                     KDRLNGAVLASDAFFPFADNVEEIAKAGIKAIIQPGGSVRDQESIEAADKYGLTMVFT
                     SVRHFRH"
     gene            14805..16067
                     /gene="purD"
                     /locus_tag="VYO11_001346"
     CDS             14805..16067
                     /gene="purD"
                     /locus_tag="VYO11_001346"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000772208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HEV1595911.1"
                     /translation="MKLLVVGSGGREHAIAKKLLESKDVKKVFVAPGNDGMTLDGLEL
                     VNISISEHSKLIDFAKTNDVAWTFIGPDDALAAGIVDDFNQAGLKAFGPTRAAAELEW
                     SKDFAKEIMVKYGVPTAIYGTFSDFEEAKAYIEKHGAPIVVKADGLALGKGVVVAETV
                     EQAVEAAHEMLLDNKFGDSGARVVIEEFLEGEEFSLFAFVNGDKFYIMPTAQDHKRAY
                     DGDKGPNTGGMGAYAPVPHLPQSVVDTAVDTIVKPVLEGVIKEGRPYLGVLYAGLILT
                     ADGPKVIEFNARFGDPETQLILPRLTSDFAQNITDILDSKEPNITWTDKGVTLGVVVA
                     SKGYPLDYSKGVELPVKTDGDIITYYAGAKFAENSRALLSNGGRVYMLVTTADTVKEA
                     QASIYQELSQQKIEGLFYRTDIGSKAIK"
     gene            16470..16958
                     /gene="purE"
                     /locus_tag="VYO11_001347"
     CDS             16470..16958
                     /gene="purE"
                     /locus_tag="VYO11_001347"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000805607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HEV1595912.1"
                     /translation="MKPVISIIMGSKSDWATMQKTAEVLDRFGVAYEKKVVSAHRTPD
                     LMFKHAEEARSRGIKIIIAGAGGAAHLPGMVAAKTTLPVIGVPVKSRALSGVDSLYSI
                     VQMPGGVPVATMAIGEAGATNAALFALRLLSVEDKSIADALANFAEEQGKIAEESSNE
                     LI"
     gene            16945..18036
                     /gene="purK"
                     /locus_tag="VYO11_001348"
     CDS             16945..18036
                     /gene="purK"
                     /locus_tag="VYO11_001348"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000099033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HEV1595913.1"
                     /translation="MSSSKTIGIIGGGQLGQMMAISAIYMGHKVIALDPAADCPASRV
                     AEIIVAPYNDVDALRQLADRCDVLTYEFENVDADGLDAVIKDGQLPQGTDLLRISQNR
                     IFEKDFLSNKAQVTVAPYKVVTSSLDLADIDLSKNYVLKTATGGYDGHGQKVIRSEAD
                     LEAAYALADSADCVLEEFVNFDLEISVIVSGNGKEVTFFPVQENIHRNNILSKTIVPA
                     RISESLVDKAKAMAVRIAEQLNLSGTLCVEMFATDDDVIVNEIAPRPHNSGHYSIEAC
                     DFSQFDTHILGVLGAPLPVIKLHAPAVMLNVLGQHVEAAEQYVTENSSAHLHMYGKIE
                     AKHNRKMGHVTLFSDVPDSVDELGEGIDF"
     gene            18046..18273
                     /locus_tag="VYO11_001349"
     CDS             18046..18273
                     /locus_tag="VYO11_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazole carboxylase"
                     /protein_id="HEV1595914.1"
                     /translation="MIQIIVNTFIEKDRTGAVVEVLYASADQDKVQAKYEELAAQYPE
                     NYLAIYDVPLDTDLNTLDHYPSVFIEKEEFE"
     gene            18336..19634
                     /gene="purB"
                     /locus_tag="VYO11_001350"
     CDS             18336..19634
                     /gene="purB"
                     /locus_tag="VYO11_001350"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HEV1595915.1"
                     /translation="MINRYSRPEMANIWSEENKYRAWLEVEILSDEAWAELGEIPKED
                     VALIRKKADFDIDRILEIEQETRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLYKQANDIIRRDLENFTNIIADKAKEHKFTIMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAAGVEAGKISGAVGNFANIPPFVEEYVCDKLGIRAQEISTQVLPRDL
                     HAEYFAVLASIATSIERMATEIRGLQKSEQREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MTGLARVIRGHMITAYENVALWHERDISHSSAERIITPDTTILIDYMLNRFGNIVKNL
                     TVFPENMIRNMNSTFGLIFSQRAMLTLIEKGMTREQAYDLVQPKTAYSWDNQVDFKPL
                     LEADSEVTSRLTQEEIDEIFNPVYYTKRVDDIFERLGLGD"
     gene            complement(19689..23600)
                     /gene="strH"
                     /locus_tag="VYO11_001351"
     CDS             complement(19689..23600)
                     /gene="strH"
                     /locus_tag="VYO11_001351"
                     /EC_number="3.2.1.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HEV1595916.1"
                     /translation="MKHEKQQRFSIRKYAVGAASVLIGFAFQAQTVAADGVTTTTENQ
                     PTIHTVSDSPQSSENRTEETPKAELQPETPATDKVASLPKTEEKPQEEVSSTPSDKAE
                     VVTPTSAEKETANKKAEEASPKKEEAKEVDSKESNTDKTDKDKPAKKDEAKAEADKPE
                     TEAGKERAATVNEKLAKKKIVSIDAGRKYFSPEQLKEIIDKAKHYGYTDLHLLVGNDG
                     LRFMLDDMSITANGKTYASDDVKRAIEKGTNDYYNDPNGNHLTESQMTDLINYAKDKG
                     IGLIPTVNSPGHMDAILNAMKELGIQNPNFSYFGKESARTVNLDNEQAVAFTKALIDK
                     YAAYFAKKTEIFNIGLDEYANDATDAKGWSVLQADKYYPNEGYPVKGYEKFIAYANDL
                     ARIVKSHGLKPMAFNDGIYYNSDTSFGSFDKDIIVSMWTGGWGGYDVASSKLLAEKGH
                     QILNTNDAWYYVLGRNADGQGWYNLDQGLNGIKNTPITSVPKTEGADIPIIGGMVAAW
                     ADTPSARYSPSRLFKLMRHFANANAEYFAADYESAEQALNEVPKDLNRYTAESVAAVK
                     EAEKAIRSLDSNLSRAQQDTIDQAIAKLQETVNNLTLTPEAQKEEEAKREVEKLAKNK
                     VISIDAGRKYFTLNQLKRIVDKASELGYSDVHLLLGNDGLRFLLDDMTITANGKTYAS
                     DDVKKAIIEGTKAYYDDPNGTTLTQAEVTELIEYAKSKDIGLIPAINSPGHMDAMLVA
                     MEKLGIKNPQAHFDKVSKTTMDLKNEEAMNFVKALIGKYMDFFAGKTKIFNFGTDEYA
                     NDATSAQGWYYLKWYQLYGKFAEYANTLAAMAKERGLQPMAFNDGFYYEDKDDVQFDK
                     DVLISYWSKGWWGYNLASPQYLASKGYKFLNTNGDWYYILGQKPEDGGGFLKKAIENT
                     GKTPFNQLASTKYPEVDLPTVGSMLSIWADRPSAEYKEEEIFELMTAFADHNKDYFRA
                     NYNALREELAKIPTNLEGYSKESLEALDAAKTALNYNLNRNKQAELDTLVANLKAALQ
                     GLKPAATHSGSLDENEVAANVETRPELITRTEEIPFEVIKKENPNLPAGQENIITAGV
                     KGERTHYISVLTENGKTTETVLDSQVTKEVINQVVEVGAPVTHKGDESGLAPTTEVKP
                     RLDIQEEEIPFTTVTRENPLLLKGKTQVITKGVNGHRSNFYSVSTSADGKEVKTLVNS
                     VVAQEAVTQIVEVGTMVTHVGDENGQAAIAEEKPKLEIPSQPAPSTAPAEESKALPQD
                     PAPVVIEKKLPETGTHDSAGLVVAGLMATLAAYGLTKRKED"
BASE COUNT         6511 a         4716 c         5670 g         6868 t
ORIGIN      
        1 tagtaaaaaa gtgattagaa aacatctttt ttaaaaatag agatgatttt gaaacaaaaa
       61 agctaattca agacgtttcg atgccaattc aagatttgga tgaaaaaaat taatagatac
      121 tgttatacta aacttgtcaa gtttgtaaca agacaaatat taaaaataaa aaagaggtat
      181 tcgttatgaa tacaaaaaag atgtcacaat ttgaaattat ggatactgag atgcttgctt
      241 gcgttgaagg tggcggatgc aattggggag attttgccaa agcaggtgtt ggaggaggag
      301 ctatacttgg aggtgtggcc tatgcagcga catgttggtg gtaattatgg attttaaaag
      361 ttttattatt ggtttagtag ttggtatatt tggtccttat atggatgatt taattagaaa
      421 aaaattttta aagtcttcgg agaagaaaac agaaaaatct gttaaaaaat aatcaaaact
      481 ataaatgatg aatctgaatc aaaattattt tgcgcatgta aagaggagtc ttgcagtaac
      541 gaatcaaaaa aaaggagtaa ctatgaatcg taatttagaa tggtgttatc tattatgact
      601 ataaatagat cataccagag gtggcttaga aatagcaggg acattagaaa ttgaagtaac
      661 tttaaatagg atgtcgtaaa tgttgctatc aatgatttat ttgtcccaag cttgcctagg
      721 gtgtcagtaa aaaatcattt tcctttcata ccatattttt agtaggtaga acgtttgttc
      781 tgcctatttt tttatccaaa aagtgcagtt gggagggaga taggctcatt tgggaaggaa
      841 gtccagtttt tgtttagtga ttggggtaag atagttgtta tcagatgagt ttatactctt
      901 cgaaaatcaa attcaaacca cgtcaacgtc gccttgccgt atatatgtga ctgacttcgt
      961 cagtcctatc tacaacctca aaacagtgtt ttgagcagcc tgcggctagt ttcctagttt
     1021 gctctttgat tttcattgag tattagggaa aaggagatga atatgaaatt tgggaaacgt
     1081 cactatcgtc cgcaagtgga tcagatggac tgcggtgtag cttcattagc catggttttt
     1141 ggctactatg gtagttatta ttttttggct cacttgcgag aattggctaa gacgaccatg
     1201 gatgggacga cggctttggg cttggtcaag gtggcagagg agattggctt tgagacacga
     1261 gctatcaagg cggatatgac gctttttgat ttgcccgatt tgacttttcc ttttgttgcc
     1321 catgtgctta aggaagggaa attgctccac tactatgtgg tgactgggca ggataaggac
     1381 agcattcata ttgccgatcc agatcctggg gtgaaattga ccaaactgcc acgtgagcgt
     1441 tttgaggaag aatggacagg agtgactctg tttatggcac ctagtccaga ctacaagcct
     1501 cataaggatc aaaagaatgg tctgctctct tttatcccta tattagtgaa gcagcgtggc
     1561 ttgattgcca atatcgtttt ggcaacactc ttggtaacct tgattaacat tgtgggttct
     1621 tattatctgc agtctatcat tgatacctat gtgccagatc agatgcgttc gacgttgggg
     1681 attatttcta ttgggctagt catcgtctac atcctccagc aaatcttgtc ttacgctcag
     1741 gagtatctct tgcttgtttt ggggcaacgc ttgtcgattg acgtgatttt gtcctatatc
     1801 aagcatgttt ttcacctccc tatgtccttc tttgcgacac gcaggacagg ggagatcgtg
     1861 tctcgtttta cagatgctaa cagtatcatc gatgcgctgg cttcgaccat cctttcgatt
     1921 ttcctagatg tgtcaacggt tgtcattatt tcccttgttt tattttcaca aaataccaat
     1981 ctctttttca tgactttatt ggcgcttcct atctacacag tgattatctt tgcctttatg
     2041 aagccatttg aaaagatgaa tcgggacacc atggaagcca atgcggctct gtcttcttct
     2101 atcattgagg acatcaatgg tattgagact atcaagtcct tgaccagtga aagtcagcgt
     2161 taccaaaaaa ttgacaagga atttgtggat tatctgaaga aatcctttac ctatagtcga
     2221 gcagagagtc agcaaaaggc tctgaaaaag gttgcccatc tcttgcttaa tgtcggcatt
     2281 ctctggatgg gggctgttct ggtcatggat ggcaagatga gtttggggca gttgattacc
     2341 tataatacct tgctggttta ctttaccaat cctttggaaa atatcatcaa tctgcaaacc
     2401 aagcttcaga cagcgcaggt tgccaataac cgtctaaatg aagtgtatct agtagcttct
     2461 gagtttgagg agaagaaaac agttgaggat ttgagcttga tgaagggaga gatgactttc
     2521 aagcaggttc attacaagta tggctatggt cgagacgtct tgtcggatat caatttaacc
     2581 gttccccaag ggtctaaggt ggcttttgtg gggatttcag ggtcaggtaa gacgactttg
     2641 gccaagatga tggttaattt ttacgaccca agtcaagggg agattagtct gggtggtgtc
     2701 aatctcaatc agattgataa aaaagccctg cgccagtaca tcaactatct gcctcaacag
     2761 ccctatgtct ttaacggaac gattttggag aatcttcttt tgggagccaa ggaggggacg
     2821 acacaggaag atatcttacg ggcggtcgaa ttggcagaga ttcgagagga tatcgagcgc
     2881 atgccactga attatcagac agaattgact tcggatgggg cagggatttc aggtggtcaa
     2941 cgtcagagaa tcgctttggc gcgtgctctc ttgacagatg cgccggtctt gattttggat
     3001 gaggcgacta gcagtttgga tattttgaca gagaagcgga ttgtcgataa tctcatggct
     3061 ttggacaaga ccttgatttt cattgctcac cgcttgacta ttgctgagcg gacagagaag
     3121 gtagttgtct tggatcaggg caagattgtc gaagaaggaa agcatgctga tttgcttgca
     3181 cagggtggct tttacgccca tttggtcaat agctagaaag aggagaggat gaaaccagaa
     3241 tttttagaaa gtgcggagtt ttataatcgt cgttaccata atttttccag tagtgtgatt
     3301 gtacccatgg cccttctgct cgtgttttta cttggctttg caactgttgc agaaaaggag
     3361 atgagtttgt ccactagagc tactgtcgaa cctagtcgta tccttgcaaa tatccagtca
     3421 actagcaaca atcgtattct tgtcaatcat ttggaagaaa ataagctggt taagaagggg
     3481 gatcttttgg ttcaatacca agaaggggca gagggtgtcc aagcggagtc ctatgccagt
     3541 cagttggaca tgctaaagga tcaaaaaaag caattggagt atctgcaaaa gagcctgcaa
     3601 gaaggggaga accactttcc agaggaggat aagtttggct accaagccac ctttcgcgac
     3661 tacatcagtc aagcaggcag tcttagggct agtacatcgc aacaaaatga gaccatcgcg
     3721 tcccagaatg cagcagctag ccaaacccaa gccgaaatcg gcaacctcat cagtcaaaca
     3781 gaggctaaaa ttcgcgatta ccagacagtt aagtcagcta ttgaaacagg tgcttccttg
     3841 gccggtcaga atctagccta ctctctttac cagtcctaca agtctcaggg cgaggaaaat
     3901 ccccaaacta aggttcaggc agttgcacag gttgaagcac agatttctca gttagaatct
     3961 agtcttgcta cttaccgtgt ccagtatgca ggttcaggta cccagcaagc ctatgcgtca
     4021 gggttaagca gtcaattgga atcccttaaa tcccaacact tggcaaaggt tggtcaggaa
     4081 ttgacccttc tagcccagaa aatcttggag gcagagtcag gtaagaaggt acagggaaat
     4141 cttttagaca aggggaaaat tacggcaagt gaggatgggg tgcttcatct taatcctgag
     4201 accagtgatt ctagcatggt tgcagaaggt gccctactag cccaacttta tccatctttg
     4261 gaaagagaag ggaaagccaa actcacagcc tatctaagtt caaaagatgt agcaagaatc
     4321 aaggtcggtg attctgttcg ctatactacg actcatgatg ccgggaatca actttttcta
     4381 gattctacta ttacaagtat tgatgcgaca gctactaaga ctgagaaagg gaatttcttt
     4441 aaaatcgagg cggagattaa tctaacttcg gagcaggctg aaaaacttag gtacggggtg
     4501 gaaggccgtc tacagatgat tacgggcaag aaaagttatc tacgttatta tttggatcaa
     4561 tttttgaaca aagagtaatg ttcgtgtttt tagagttaaa taatttttaa actgtgagaa
     4621 agattcttct tgcagttttt tctttacaat ttttgaaaaa catctgctat ttattcggtt
     4681 aaattcttgt gttttttggt tttttgtggt aaaatgtgct caagtaatac gaaaggcgaa
     4741 ctttaaaatg tcaaaacaat tgatctattc gggaaaagct aaagatatct atacaactga
     4801 ggatgaaaat cttattattt caacttacaa ggaccaggcg actgctttca acggtgtcaa
     4861 gaaggagcag attgcaggta agggagtctt gaataatcag atctcatctt ttatttttga
     4921 gaaattaaat gcggctggtg tggcgactca ctttgtggag aaactttcag acacggaaca
     4981 actcaataaa aaggttaaga ttattccttt ggaagtcgtg ctccgcaact atactgctgg
     5041 ttccttttca aaacgttttg gtgtggatga gggaatcgcc ttggagactc cgattgtcga
     5101 attttactac aaaaatgatg atttggatga tccatttatc aatgatgagc atgtgaaatt
     5161 cctacagatt gcggatgacc agcagattgc ctacttgaag gaagaaacgc gtcgtatcaa
     5221 tgaactattg aaagtctggt ttgctgagat tgggcttaaa ttgattgact ttaagctaga
     5281 gttcggtttt gacaaggatg gcaagattat cttggcagac gaattttcac cagataactg
     5341 ccgcttgtgg gatgctgatg gcaaccacat ggataaggat gttttccgta gaggattggg
     5401 agaactaacc gacgtttatg agattgtttg ggaaaagttg caggaattga aataatctgt
     5461 ttgcaatgga aaaccttcgt ctctcaacta aaaggactca ggctgaaaag gtcccccaga
     5521 ccttttcact ctgtagagaa ctaggtgaac caaccgatgt ttacgaaatt gtctgggaaa
     5581 agttgcaggg tttaaaataa caacctcaag gctgtttggg aatattgcaa gagctgaaat
     5641 aaaggaataa gaattgatgg ataaacgtat ttttgttgaa aaaaaggctg attttcaggt
     5701 caagtcagag agtttggtta gagagctcca gcacaacttg ggactgtcaa gcttgaaaag
     5761 tattcgtatt gtgcaagtat atgatgtatt tgacttggct gaggacttgt ttgcacctgc
     5821 agagaagcac attttctctg agcaggtaac cgaccatgtt ttagatgaag tatctgtgca
     5881 ggcggatctt gctaactatg ctttctttgc cattgaaagt ctgccagggc agtttgacca
     5941 gcgtgcagct tcgtcacagg aagccttgct tttgttggga agttcgagtg acgtgacagt
     6001 caacacagcc caactttact tggtgaataa agatattgat gcgactgagt tggaagctgt
     6061 caaaaactac ctgctcaatc cagttgattc tcgtttcaag gatatcacga cagggattgc
     6121 caagcaggag ttttcagagt cagacaagac cattccaaaa ttgactttct ttgaaagcta
     6181 tacagcagaa gactttgctc gctacaaggc cgaacaaggg atggccatgg aagtggatga
     6241 tttgctcttt atccaagact actttaagtc aatcgggcgc gtgccaactg agactgaact
     6301 taaggttttg gacacttact ggtctgacca ctgccgtcat acgacttttg agacagagtt
     6361 gaaacacatc gacttttcag cttctaaatt tcaaaagcaa ttgcagtcaa cctatgacaa
     6421 gtatattgcc atgcgcgagg aattaggtcg gtctgaaaaa ccacaaacct tgatggatat
     6481 ggcgactatt ttcggtcgtt atgagcgtgc taatggacga ttggatgata tggaagtctc
     6541 tgacgaaatc aatgcctgct cagttgaaat tgaagtggac gttgatggtg tcaaggaacc
     6601 ttggctcctc atgtttaaaa acgaaaccca caaccatcca acagaaattg agccatttgg
     6661 tggagcggct acctgtattg gtggagctat tcgtgatccg ttgtcaggcc gttcctatgt
     6721 ttaccaagcc atgcgtattt caggtgctgg tgatattaca gcaccgattt cggaaactcg
     6781 cgctgggaaa ttgccacaac aagtcatttc taaaacagca gctcatggtt attcttcata
     6841 tggtaaccag attgggcttg caacaaccta cgttcgtgaa tacttccacc caggctttgt
     6901 agctaaacgt atggaacttg gtgccgttgt tggtgcggct cccaagggca atgttgtccg
     6961 tgaaaaacct gaagcaggtg atgtgatcat ccttctcgga ggcaaaacag gtcgtgatgg
     7021 tgtcggtggt gcgacgggct cttctaaggt tcaaacagtt gagtctgtag agactgctgg
     7081 tgctgaggtt caaaaaggaa atgccatcga agaacgcaag attcagcgcc tcttccgtaa
     7141 tggcaatgtc actcgtctga tcaagaagtc caatgacttt ggggcaggcg gtgtctgtgt
     7201 ggctatcggt gaattggcag acggtcttga aatcgacctc aacaaggtgc ctcttaaata
     7261 ccagggcttg aatggtacag aaattgccat ctctgaatca caagaacgga tggcggtcgt
     7321 ggttcgtcct gaagatgtgg ataccttcgt tgccgaatgt aacaaagaaa atattgatgc
     7381 tgttgtggtg gcgacagtaa ctgaaaaacc aaatcttgtc atgcactgga atggtgagac
     7441 aatcgttgac ttggagcgtc gtttccttga caccaatggt gtgcgcgtgg ttgtcgatgc
     7501 caaagttgtg gacaaggatg tcaaactccc agaagagcgt caaacatctg ctgaaacact
     7561 ggaatcagat acccttacgg ttctatctga cctcaaccat gcaagtcaaa aaggattaca
     7621 gactatcttt gactgctctg ttggacgctc aacggttaat cacccacttg gtggtcgtta
     7681 ccaactcaca ccaactgagg catctgtgca gaaattgcca gttcaacacg gtgtgactca
     7741 tactgcgtcg gtcattgctc aaggtttcaa cccatatgta gctgaatggt ctccatacca
     7801 cggtgctgct tatgcggtta tcgaagcaac tgctcgtttg gtggctgctg gtgccaactg
     7861 gtccaaggct cgtttctctt accaagagta tttcgagcgg atggacaaac aagcagagcg
     7921 tttcggtcag ccagtagccg cccttctagg ttctattgaa gcacaaattc agcttggctt
     7981 gccatctatc ggtggtaagg actccatgtc tggtaccttt gaagaattga ccgttccgcc
     8041 aaccttggct gcctttgggg tgacgacggc agatagccgt aaggtgctct ctccagaatt
     8101 taaagctgtt ggggaaaata tctactacat cccaggtcaa gccctctctg cagagattga
     8161 ttttgacttg attaagaaaa attttactca gtttgaagcc atccaagctg accataaagt
     8221 gacatctgca tcagctgtca aatacggtgg tgtagttgaa agtttggctc ttgctacctt
     8281 tggaaactat attggtgcag aggtgacctt gcctgaactt aaaacagctt tgacagctca
     8341 attaggcggc tttgtcttca catctcctga agaaattgct ggagtagaga aggttggaca
     8401 aacgaaagca gactttacac tgactgtcaa ccgtgtgaaa ctagatggac acaagcttga
     8461 cagtgcattt caagggacat tggaagaagt ttacccaaca gaatttaccc gagcgaaaga
     8521 actagaagaa gtaccagctg tggcatcaga tgttgtgatt aaagccaaag aaaaggttga
     8581 aaaacctgtg gtttacatcc cagtctttcc aggaaccaac tcagaatatg attcagctaa
     8641 ggccttcgaa aaagaaggtg cagaggtcaa tttggtgcca ttcgtgacct tgaatgaaga
     8701 agctattgtc aagtcagttg aaactatggt tgacaatatc gacaagacta atattctctt
     8761 ctttgctggt ggattctcgg ctgcggatga accagatggt tcagctaagt ttatcgtcaa
     8821 tatcctgctt aatgaaaaag tgcgtgtggc tattgatagc tttatcgccc gtggtggttt
     8881 gattatcggt atttgtaatg gattccaagc cttagtcaaa tcgggtctcc taccctacgg
     8941 aaactttgaa gctgctaaca gtactagccc aaccctcttc tacaatgatg ccaaccaaca
     9001 cgtggccaag atggtggaaa ctcgtattgc caataccaac tcaccatggt tggctggtgt
     9061 gcaagtgggc gatatccacg ctattcctgt ttcgcacggt gaagggaagt ttgtcgtgac
     9121 ggctgaggaa tttgcagagc tccgtgacaa tggacaaatt ttcagccaat acgttgactt
     9181 taacggtaaa ccaagtatgg attctaagta caatccgaat ggttctgtcc atgccatcga
     9241 aggaattacc agcaagaatg gtcaaatcat cggtaagatg ggccactcag aacgttatga
     9301 ggatggtctt ttccaaaata tcccaggcaa taaagaccaa cacctgttcg catcagcggt
     9361 taaacatttc actggaaaat aagacttaca gattttctaa tagatagtat cagtaatgta
     9421 aaagtcatgt aaatctagct cttgatgatt acaaatgaaa attaggtata aaaaatgaca
     9481 tacgaagtaa aatctcttaa tgaagaatgt ggtgttttcg gtatttgggg acatccagat
     9541 gctgctaagt tgacctattt tggactccac agtcttcaac accgtggtca ggagggggca
     9601 ggaatcctct ccaatgatca aggacaactg aagcgccatc gtgacatggg gcttttatca
     9661 gaagttttca gaaatccagc caatttggat aaattgacag gagctggtgc gattgggcat
     9721 gtgcgttatg cgactgctgg cgaagcttct gttgataaca tccaaccctt cctcttccgt
     9781 tttcacgata tgcagtttgg tttggctcat aatggaaatc tgaccaatgc agcctctctc
     9841 aagaaagaac tggaacaaag aggagcaatt ttcagcgcga cttcggactc tgaaatcttg
     9901 gctcacctca ttcgtcgcag tcataatcct agcctgatgg gcaaaatcaa ggaagcgctc
     9961 agtcttgtca aaggtggttt tgcctatatc ttgctgtttg aggacaagtt gattgcggct
    10021 cttgacccta atggctttcg tccgctttct atcgggaaaa tggccaacgg agcggtggtt
    10081 gtttcctctg aaacctgtgc ttttgaggtc attggtgccg agtggatttg tgatttgaag
    10141 ccaggtgaga ttgtgatcat tgatgacgag ggcattcagt atgacagcta tacagatgat
    10201 acccagttgg cgatttgttc tatggagtat atctactttg cccgccctga ttctaatatc
    10261 cacggtgtca atgtccatac ggcacgtaag agaatgggag cgcaattggc gcgagaattt
    10321 aagcatgagg cagatattgt agttggtgtg cccaattctt ccctaagcgc ggctatggga
    10381 tttgcggaag aatcaggctt accaaatgaa atgggtctga tcaaaaacca atacacccag
    10441 cgaactttta tccaaccgac tcaagaattg cgggagcaag gagtgcggat gaaactgtct
    10501 gctgtttcgg gtgttgtcaa aggcaaacgt gtggtcatgg tggatgattc cattgtacgt
    10561 ggaacaacct ctcgtcgtat cgttcagctc ttgaaagaag cgggtgcgac tgaggttcac
    10621 gttgccattg gaagtcctgc actagcgtat ccatgtttct acgggattga tatccagacc
    10681 cgtcaggagc tgattgcagc caatcatacg gtcgaagaaa ctcgccaaat cattggtgcg
    10741 gacagtctga cttatctttc aattgatggc ttgattgagt cgattggtat cgaaacagat
    10801 gcgccgaacg gtggtctctg tgtcgcttac tttgacggtg actacccaac gcctctctat
    10861 gactacgaag aagactatcg tagaagtttg gaagaaaaga ccagttttta caagtaggcg
    10921 acagattctc cattaaagaa aaggaaaaaa caaatgacaa ataaaaatgc atatgcccag
    10981 tcgggtgtgg atgttgaagc gggttatgaa gttgttgaac ggattaaaaa gcacgtggcc
    11041 cgtacggagc gtgcaggtgt catgggagct cttggtggct ttggtggtat gtttgacctt
    11101 tccaagactg gggttaaaga acccgtcttg atttcaggga ctgacggtgt cggaaccaag
    11161 ctcatgttgg ctatcaagta cgacaagcac gataccatcg ggcaggactg tgtggccatg
    11221 tgtgtcaacg acatcattgc tgcaggtgcg gaacccctct attttctcga ctacgtagcg
    11281 acagggaaga atgaaccagc taagctagaa caagtggttg ctggtgtggc agaaggttgt
    11341 gtgcaggctg gtgctgccct catcggtggg gaaacggctg aaatgccggg catgtacggc
    11401 gaagacgact atgacttggc tggttttgcg gtcggtgtgg ctgaaaaatc tcaaatcatt
    11461 gacggttcaa aggtggtaga gggagatgtt cttctcggac ttgcttcaag tgggattcac
    11521 tcaaatggtt actctttggt tcgtcgtgtc tttgcggatt acacaggtga ggaagtccta
    11581 ccagaattgg aaggcaagaa acttaaggaa gttctacttg agccgactcg tatctatgtc
    11641 aaggctgtct tgccgctcat caaagaagag ttggtcaacg gcattgccca catcacaggt
    11701 ggtggcttta tcgaaaatgt ccctcgtatg tttgcagatg acctagctgc tgaaattgat
    11761 gaaagcaaag ttccagtgct tccaattttc aaagcccttg aaaaatatgg tcagattaaa
    11821 cacgaagaaa tgtttgaaat cttcaatatg ggtgtgggac ttatgttggc ggtcagccct
    11881 gaaaatgtag agcgtgtaaa agaattgttg gatgaagcag tctatgaaat tggtcgcatc
    11941 gtcaagaaag aaaacgaaag tgtcattatc aaatgaaaaa aatagcggtt tttgcctctg
    12001 gtaatggctc aaattttcag gtgattgccg aagaatttcc agtggagttt gtcttttcag
    12061 accatcgtga tgcctatgtg cttgagcgtg caaagcagct cggcgttctg tcctatgctt
    12121 ttgaactcaa ggagtttgag agcaaggcag actacgaagc agcccttgtc gaactcttgg
    12181 aagaacacca gattgacttg gtttgcctag caggctacat gaaaatcgtt ggaccaacct
    12241 tattgtcggc ttatgaaggt cggattgtca acattcatcc agcctacttg ccagaatttc
    12301 caggagctca tgggattgag gatgcttgga atgctggcgt gggtcagtct ggtgtgacca
    12361 ttcactgggt ggattcgggt gtggatacag gccaggtcat caaacaggtt cgtgtgccac
    12421 gactagctga tgataccatt gacagatttg aagctcgcat ccatgaagca gagtacaggc
    12481 tgtatccgga agtagtgaag gctctattta cagattgact ttttgatgat tcatatgata
    12541 tctttgattt taaattggag tcagtgtttg ttgaagacgg cttcaaacgg aggtatttgt
    12601 aatgttagaa tctaaaaaaa caactcgata tgtattttat gtctatctga tgttattaac
    12661 ttggggaatc ttatttaagt ttgaaacaaa tcctgaattt atagcatttt tcttagctcc
    12721 aaggtatatc aattggattc cattttcaga accactaata gtcgatggaa aaattgtttt
    12781 tgctgaaatg ttatttaatc tgattttctt tattccatta ggtgtttgtt tccctttgat
    12841 aaaaactaat ttatctagtt taagaatagt cgggacaggt ttcttgatta gtttattgtt
    12901 tgagtgctta cagtatattt tagcaatagg tataacagat ataacggatt tgactttaaa
    12961 tacgctaggt gtctgtgtag gattactgat ttatcaaatt tttataagag tgttcaaatc
    13021 acagactaga aaatggatca atatcttagg tatgcttagc cttggttttg cttatcttgt
    13081 tttactgtta ctgcatttaa ttggtgttta actaatgatt aaaaaggaga atataatgac
    13141 taaacgcgtc ttaatcagcg tctcagacaa agcgggcatt gttgaatttg cccaagaact
    13201 caaaaaactt ggttgggaga ttatctcaac aggtggaact aaggttgccc ttgataatgc
    13261 tggggtggat accattgcta tcgatgatgt gactggtttc ccagaaatga tggacggtcg
    13321 tgtgaagacc ctccacccaa atatccacgg agggcttctc gctcgtcgtg acttggatag
    13381 ccacttggaa gcggctaagg acaacaagat tgagctcatt gaccttgtgg tggtcaacct
    13441 ttacccattt aaggaaacta tccttaaacc agatgtgact tatgctgatg cagttgaaaa
    13501 tatcgatatt ggtgggccgt ctatgcttcg ttcagcagcg aaaaatcatg ccagtgttac
    13561 agttgtggta gatcctgctg actacgctgt ggttttggac gaattggcag caaacggcga
    13621 aacctcttat gaaactcgcc aacgtttagc agccaaagta tttcgtcaca cagcggctta
    13681 tgacgccttg attgcagaat acttcacagc tcaagtgggt gaaagcaagc ctgaaaaact
    13741 cactttgact tatgacctca agcaaccaat gcgttacggt gagaatcctc aacaagacgc
    13801 ggacttttac cagaaagctt tgcctacaga ctactccatt gcttcagcca aacagctcaa
    13861 cgggaaagaa ttgtcattta ataatatccg tgatgcagat gctgctatcc gtatcatccg
    13921 tgacttcaaa gatagtccaa ccgttgtggc tctcaaacac atgaatccat gtggaattgg
    13981 tcaagctgat gacatcgaga ctgcttggga ctacgcttat gagtctgacc cagtatctat
    14041 ctttggtggg attgtcgtcc tcaaccgtga ggtggatgct gcgacagctg agaagatgca
    14101 cggcgttttc ctcgaaatca tcattgcacc aagctatacg gatgaagcgc tagctatttt
    14161 gatcaataaa aagaaaaact tgcgtatcct tgccttgcca tttaatgctc aagaggctag
    14221 cgaagtggaa gcagaataca caggtgtagt cggtggactt ctcgtgcaaa atcaagacgt
    14281 ggtcaaggaa agcccagctg actggcaagt ggtgaccaaa cgtcagccaa ctgagacaga
    14341 agcgactgct cttgagttcg cttggaaggc tatcaagtac gtcaaatcaa atggtattat
    14401 cgtgaccaac gaccacatga cacttggtgt tggtccaggt caaaccaacc gtgtggcttc
    14461 tgttcgcctt gccattgacc aagccaaaga tcgtctgaac ggggcggtcc ttgcttcaga
    14521 tgccttcttc ccatttgcgg ataacgtgga agaaatcgcc aaagcaggaa ttaaggccat
    14581 catccagccc ggtggctctg tccgtgacca agaatccatc gaagcagcgg ataaatacgg
    14641 cttgactatg gtctttacaa gtgtgagaca ttttagacat taagaagata aaagggaaga
    14701 aaacagtttc tttccttttt tggcttaaaa tgctaactga aacaagatta aaacgaactt
    14761 ttttgatata atgttggtaa ataattcgca aaagaggttg aggaatgaaa ctgcttgttg
    14821 tcggttctgg tggtcgtgag catgcgattg ctaaaaagtt acttgaatca aaagacgtga
    14881 aaaaagtctt tgtagctcct gggaatgatg ggatgactct ggatggtttg gaattggtaa
    14941 atatctctat ttccgaacat tctaaattga ttgacttcgc aaagaccaat gatgttgctt
    15001 ggacctttat cggtccagat gatgcccttg ctgctggtat cgtggatgat tttaaccaag
    15061 ctgggcttaa ggcctttggt ccgactaggg ctgcagcgga gctggagtgg tccaaggatt
    15121 tcgccaagga aatcatggtc aaatacggcg ttccgacagc aatatatggc acattttcag
    15181 atttcgagga agccaaggcc tatatcgaaa agcatggtgc gcctatcgta gtcaaggcgg
    15241 atggcttggc acttgggaag ggtgtcgtcg ttgctgagac ggttgagcaa gcggtcgaag
    15301 ccgctcatga gatgcttttg gacaataaat ttggtgactc aggtgcgcgc gtggttattg
    15361 aggaattcct tgaaggagag gaattttcac tctttgcctt tgtcaatggt gataagttct
    15421 acatcatgcc aacggctcag gaccacaaac gtgcctatga tggcgacaaa gggcctaaca
    15481 cgggtggtat gggtgcctat gcgccagttc cacacttacc acagagtgta gttgatacag
    15541 cggttgacac cattgtcaag ccagttctag aaggggtgat taaagaaggt cgtccttatc
    15601 tgggagttct ttacgcaggg cttatcctga cagctgatgg accgaaggtc atcgagttca
    15661 acgctcggtt cggagatcca gaaactcagc ttatcttgcc tcgcttaacc tctgactttg
    15721 ctcaaaatat cacagatatc ctggatagca aggagccaaa tatcacgtgg acggacaagg
    15781 gtgtgactct gggtgtggtt gtcgcatcca agggctaccc gctagattat tcaaagggtg
    15841 ttgagttgcc agtcaaaacc gatggcgaca tcattaccta ctatgcaggg gctaagtttg
    15901 cggaaaatag cagagcactg ctctcaaacg gcggacgagt ttatatgctc gttaccacag
    15961 cagataccgt caaagaagcc caagccagca tctaccaaga actatcccaa caaaaaatag
    16021 aaggactctt ctaccgaaca gatatcggaa gcaaggcaat taagtaaaga tataagaata
    16081 acgcgccgta gtcgccaaac acgataatgg tcgtcgtggt gaaaagacca gaacagtgaa
    16141 tgttctggtc agggggaaac ttggagaccg taggctcaaa gtttaggaat gaaaccgaag
    16201 gtttgcttcc gcctccatca cctaagacca ttatcaaaaa gaaaaataaa aattcacaaa
    16261 atacgttaat ggtcgtatgg tttgcgagcg ttagcgagct aatatagaat aatcaccgcc
    16321 gttgtgaaag aacgattgga tgacaatcca atcgttcagg gaaattggaa gaccttgggt
    16381 ttccaattta ggcatgagac acctttggtg gctgctgccg tccctcacaa gctaaggtga
    16441 ttgttgaaaa agaggaaaaa ggagaagaaa tgaaaccagt aatttccatc atcatgggct
    16501 caaaatccga ctgggcaacc atgcaaaaaa cagcagaagt cctagaccgc ttcggtgtag
    16561 cctacgaaaa gaaagttgtt tccgcacacc gtacaccaga cctcatgttc aaacatgcag
    16621 aagaagcccg tagtcgtggc atcaagatca tcatcgcagg tgctggtggc gcagcgcatt
    16681 tgccaggcat ggtagctgcc aaaacaaccc ttccagtcat tggtgtgcca gtcaagtctc
    16741 gtgctcttag tggagtggat tcactctatt ctatcgttca gatgccgggt ggggtgcctg
    16801 ttgcgaccat ggctatcggt gaagctggag cgactaacgc agctctcttt gccctccgtc
    16861 tcctctctgt agaagataag tccattgcgg atgcacttgc caactttgct gaagaacaag
    16921 gaaaaatcgc agaggagtcg tcaaatgagc tcatctaaaa caatcggaat tatcggtggc
    16981 ggtcaactgg gtcagatgat ggccatttct gctatctaca tgggccacaa ggttatcgcg
    17041 ctggatcctg cggcggattg cccggcctct cgcgtggcgg aaatcattgt ggcaccttat
    17101 aacgatgtgg acgccctccg tcagttggca gaccgttgcg atgtcctcac ttatgagttt
    17161 gaaaatgtcg acgctgacgg tttggatgcc gttatcaagg atggacaact ccctcaagga
    17221 acagatctgc tccgcatttc gcaaaatcgt atttttgaaa aggacttttt gtcaaacaag
    17281 gctcaagtca ctgtggcacc ctacaaggtc gtgacttcta gcctagactt ggcagatatc
    17341 gacttgtcga aaaactatgt cctcaagact gcgactggtg gctacgatgg tcatggacaa
    17401 aaggttattc gttcagaagc agacttggaa gcagcctatg cgctagcaga ctcagcagac
    17461 tgcgtcttgg aagaatttgt caactttgac cttgagattt ctgtcatcgt gtcaggaaat
    17521 ggcaaggagg tgacgttttt cccagttcag gaaaatatcc accgcaacaa tatcctgtct
    17581 aagaccatcg taccagcccg catttctgaa agtctagtag acaaggctaa agctatggca
    17641 gtgcgaatcg cagaacaact caacttgtct ggaactctct gtgtggaaat gtttgcgact
    17701 gatgatgacg ttattgtcaa tgaaatcgcc ccacgaccac ataactctgg gcactattct
    17761 attgaagcct gtgatttctc tcagtttgac acccatattc tcggtgttct cggagcacca
    17821 ttaccagtca tcaaactcca tgcgccagcc gttatgctta atgtcctcgg tcagcatgtc
    17881 gaggctgctg agcaatatgt gacagaaaat tcaagcgccc acctccacat gtatggtaaa
    17941 atagaagcga agcacaaccg caagatggga catgtgacct tgtttagtga tgtaccggat
    18001 agtgtggatg agcttgggga agggattgat ttttaggaca agtctatgat acaaattatc
    18061 gttaatacat ttattgaaaa ggataggact ggagcagttg ttgaagtgtt gtatgccagt
    18121 gctgaccaag ataaggtaca agctaaatat gaagaactag ctgcacaata ccccgaaaat
    18181 tatttagcta tctatgatgt accgctggat acggatttga atacactaga tcattacccg
    18241 tctgtgttta ttgaaaaaga ggagtttgag tagaaatctt ggtttaccta gatagcttat
    18301 tcccaacagc ttaagaagaa aggaaaaatt aacacatgat caaccgttac tctcgccctg
    18361 agatggcgaa tatttggagt gaagaaaata aataccgtgc ttggcttgag gtggaaatcc
    18421 tctctgacga ggcatgggct gagttggggg aaatccctaa ggaagatgtg gctttgattc
    18481 gcaagaaggc ggactttgac atcgaccgta ttttggaaat tgagcaggag acgcgccacg
    18541 atgtggtggc tttcacgcgt gcggtttctg agactcttgg tgaagagcgc aagtgggttc
    18601 actatgggtt aacttctacc gacgtggtgg atactgctta tggttacctc tacaagcagg
    18661 ccaacgacat catccgtcgt gaccttgaaa acttcactaa tatcatcgct gacaaggcca
    18721 aggagcacaa gttcaccatc atgatggggc gtactcatgg tgtgcacgct gagccgacaa
    18781 cctttggtct taaattggca acttggtaca gcgaaatgaa acgcaatatc gagcgtttcg
    18841 agcatgcagc tgctggtgta gaagctggta agatttctgg tgcggttggg aactttgcca
    18901 atatcccacc atttgtagag gagtatgtct gcgataaact tggcatccgt gcccaagaaa
    18961 tctctacaca agtccttcct cgtgaccttc acgctgagta ctttgcggtt cttgccagca
    19021 ttgcgacttc aatcgaacgt atggcgactg agattcgtgg tctacaaaaa tctgagcaac
    19081 gcgaagtaga agagttcttt gctaaagggc aaaaaggatc ttcagcaatg cctcacaaac
    19141 gcaacccaat cggttctgaa aatatgactg gtctggcgcg tgtcattcgt ggtcacatga
    19201 ttacggctta tgaaaacgtc gctctctggc acgaacgcga tatttcccac tcatcagctg
    19261 agcgtatcat cacaccagat acgaccattt tgattgacta catgctcaac cgttttggaa
    19321 atatcgtcaa gaacttgaca gtcttcccag aaaatatgat ccgaaacatg aactcgactt
    19381 ttggtcttat ctttagccaa cgggctatgt tgacattgat tgaaaaaggc atgacccgtg
    19441 agcaagccta tgacttggtg caaccaaaaa cagcctactc ttgggacaac caagtagact
    19501 ttaaaccact tcttgaggca gattcagaag taacatcacg tctcactcaa gaagaaatcg
    19561 atgaaatctt caacccagtt tattacacca aacgagtgga tgatatcttt gaacgtcttg
    19621 gactaggtga ttaattaaaa aataaacagc gagcttcaat ctcgctgttt attttttatc
    19681 gaaaagactt agtcttcttt tcttttagtg agtccatagg ctgctagtgt ggccatgagt
    19741 cctgcgacta ctagtcctgc agaatcgtga gttcctgttt caggaagttt tttctctatt
    19801 accacaggag ctggatcttg aggaagagct ttgctttcct cagcaggagc agttgatgga
    19861 gctggttggc ttgggatttc tagttttggt ttttcttcag caatagcggc ttgtccgttt
    19921 tcatcgccta catgtgttac catagttccg acttcgacta tttgagtaac ggcttcctgt
    19981 gctacgacac tatttacaag tgttttcact tccttaccat cggcagaagt gctcacagag
    20041 tagaagttgc tacgatgtcc attgacgccc ttagtaatga cttgtgtttt tcctttgagt
    20101 aagagtggat tttcacgagt cactgtggta aatggaattt cttcttcttg gatatccagt
    20161 ctaggtttta cctcagtagt tggtgcaaga ccactttcat cacccttgtg agttacagga
    20221 gcgccaactt caaccacttg gtttataact tctttggtta cctggctatc aaggactgtt
    20281 tctgttgttt ttccattttc agtgagtaca gagatgtaat gagttcgttc acctttgact
    20341 cctgctgtga taatattttc ctgaccagct gggaggttag gattttcttt cttgataact
    20401 tcaaatggaa tttcttcagt tcttgtgatg agttctggtc tggtttcaac attggcagcc
    20461 acttcatttt catccaggct tcctgaatga gttgcagctg gtttgaggcc ttgaagagcg
    20521 gcttttaggt tggctacaag tgtgtcaagc tcagcttgtt tattacggtt gaggttgtaa
    20581 tttagagctg ttttagctgc gtcaagggcc tcaagacttt ctttactata tccttctaag
    20641 tttgtaggaa ttttagctaa ttcttcgcgg agagcattat aattagcacg gaagtagtct
    20701 ttgttgtggt ctgcaaaggc agtcatgagt tcaaagattt cctcttcctt gtactcagcg
    20761 cttggtctat ctgcccagat tgaaagcata cttccgactg ttggaagatc tacttcagga
    20821 tatttggtag aagctagttg attgaatggt gtttttccag tattctcaat agctttcttg
    20881 aggaaaccac caccatcttc tggtttttga ccaagaatgt agtaccagtc accgttggta
    20941 ttcaagaatt tatagccttt gcttgctagg tattgaggtg atgcgaggtt atatccccac
    21001 cagcctttag accagtaaga aatcaagaca tctttgtcaa actgaacatc gtccttgtct
    21061 tcatagtaga agccatcgtt gaaggccatt ggttgaagcc ctctttcttt ggccatagct
    21121 gcgagggtgt tggcatattc ggcaaatttg ccatagagtt gataccactt gaggtagtac
    21181 cagccttggg cactagtcgc atcgttggcg tattcgtcag taccaaagtt gaaaatcttt
    21241 gttttacctg caaagaagtc catgtattta ccgatgaggg cttttacaaa gttcatcgct
    21301 tcttcgtttt tcaagtccat agttgttttt gaaactttat caaagtgggc ttgaggattt
    21361 ttaataccta atttttccat ggcaaccagc atagcatcca tgtgacctgg actgttaata
    21421 gctgggatga gaccgatgtc cttagattta gcgtattcaa ttagctctgt cacttctgcc
    21481 tgtgttagtg tagtaccgtt tggatcgtcg tagtaagctt tagttccttc gataatagct
    21541 tttttaacgt catcactagc ataggttttt ccgttggcag taatggtcat atcatcgagt
    21601 agaaagcgaa gtccgtcatt tcctagaagg agatggacat cagaatatcc gagttcactg
    21661 gccttgtcta cgatgcgttt gagctggttc agagtaaagt atttgcgtcc agcatcgatt
    21721 gagattacct tgtttttggc aagtttttca acctcacgtt tagcttcttc ttctttttga
    21781 gcttcaggcg tgagggtcaa gttgttgaca gtttcttgaa gtttagcaat ggcttgatca
    21841 atcgtatctt gttgggcacg gctaaggttg ctatcgagag agcgaatagc tttttcagct
    21901 tcttttacgg ccgcgacgct ttctgcagta taacggttca ggtcttttgg tacctcgtta
    21961 agtgcttgct ctgcagattc ataatcagct gcgaagtatt cagcgttggc atttgcaaaa
    22021 tgacgcatga gtttgaagag gcgtgatggt gaataacgtg cagatggagt gtcagcccaa
    22081 gcagctacca taccaccgat gattgggata tcagctcctt ctgtttttgg tacagaagtg
    22141 attggtgtgt ttttaatacc attgagcccc tgatcgagat tgtaccagcc ttggccatca
    22201 gcgtttcgtc caagaacgta gtaccaagca tcattggtat taaggatttg gtgacctttt
    22261 tcagctagta gtttagaaga agcgacatcg tagcctcccc aaccaccagt ccacatagaa
    22321 acgatgatgt ctttgtcaaa actaccaaag cttgtgtcgc tattgtagta gataccgtcg
    22381 ttaaaggcca ttggtttgag accgtgcgat tttacaatac gagcgaggtc attggcgtag
    22441 gcaataaatt tttcatagcc ttttacaggg tagccttcgt ttggatagta tttatcagct
    22501 tgaagcacac tccaaccttt agcatctgtc gcatcattgg catattcatc aagtccgatg
    22561 ttgaagattt cagtcttttt cgcgaaataa gcagcatact tgtcgataag ggcttttgta
    22621 aaagcgacag cttgttcgtt gtcaagattg acagtacggg ctgattcctt cccaaaatag
    22681 ctaaagttag ggttttggat tcccaattct ttcatggcat tgagaatcgc atccatgtga
    22741 ccaggactat ttactgtcgg aatgagaccg atacctttat ctttggcata gttaatcaga
    22801 tctgtcattt gactttctgt taagtgattg ccgtttggat cgttgtaata atcatttgta
    22861 cctttttcaa tggcgcgttt gacatcgtca ctggcatagg tcttgccgtt agctgtgatg
    22921 ctcatatcgt ccaacatgaa acggagtcca tcatttccga ctaataggtg taaatcagtg
    22981 tagccataat gtttcgcttt atcgatgatt tccttgagct gttctggtga gaaatattta
    23041 cgtccagcat caatagaaac aattttcttt ttcgctagtt tttcatttac agttgcagca
    23101 cgttcctttc ctgcctctgt ttccggtttg tcagcctctg ctttcgcttc atctttttta
    23161 gctggtttat ccttgtcagt cttgtctgta tttgactctt tagaatcaac ctctttcgct
    23221 tcttcctttt tagggctagc ttcttctgcc tttttattag cagtttcttt ttcagcagaa
    23281 gttggagtta ccacctctgc tttatcacta ggagttgaac taacttcctc ttgtggtttt
    23341 tcttctgttt ttggaagact agctacctta tcagtagctg gagtttctgg ttgaagctct
    23401 gctttaggtg tttcctcagt ccgattttcg gatgattgag gggaatcaga aactgtatgg
    23461 atggtcggtt ggttttctgt agtagtagta actccatcgg ctgcaacagt ctgtgcttgg
    23521 aaggcaaatc caattagaac agaagctgct cctacagcgt atttacgaat agaaaaacgc
    23581 tgttgttttt catgtttcat tgcaaaacct cctgattgca ttgttatatt gatagcgatt
    23641 atataaatca acgcccttat tttatttctt atattaacga gagtcaagag gagatgacaa
    23701 aaaactataa taagtataaa aaaatataaa atttaaactt aagatttcag attggtcgga
    23761 aaaaa
//
LOCUS       DAVLXH010000032        22378 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00028199
            SAMN33607166-rid17955573.denovo.032, whole genome shotgun sequence.
ACCESSION   DAVLXH010000032 DAVLXH010000000
VERSION     DAVLXH010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607166
            Sequence Read Archive: SRR23725544
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22378)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22378)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721421.1
            Genome Coverage       :: 115x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:42:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,210
            CDSs (total)                      :: 2,161
            Genes (coding)                    :: 2,023
            CDSs (with protein)               :: 2,023
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 73 of 138
            Pseudo Genes (incomplete)         :: 60 of 138
            Pseudo Genes (internal stop)      :: 40 of 138
            Pseudo Genes (multiple problems)  :: 31 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22378
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607166-rid17955573.denovo.032"
                     /strain="AUSMDU00028199"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1349"
     gene            5..75
                     /locus_tag="VYO11_001352"
     tRNA            5..75
                     /locus_tag="VYO11_001352"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:37..39,aa:Gly,seq:tcc)
     gene            110..183
                     /locus_tag="VYO11_001353"
     tRNA            110..183
                     /locus_tag="VYO11_001353"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:144..146,aa:Ile,seq:gat)
     gene            266..355
                     /locus_tag="VYO11_001354"
     tRNA            266..355
                     /locus_tag="VYO11_001354"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:302..304,aa:Ser,seq:tga)
     gene            366..439
                     /locus_tag="VYO11_001355"
     tRNA            366..439
                     /locus_tag="VYO11_001355"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:400..402,aa:Met,seq:cat)
     gene            443..515
                     /locus_tag="VYO11_001356"
     tRNA            443..515
                     /locus_tag="VYO11_001356"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:476..478,aa:Phe,seq:gaa)
     gene            528..608
                     /locus_tag="VYO11_001357"
     tRNA            528..608
                     /locus_tag="VYO11_001357"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:562..564,aa:Tyr,seq:gta)
     gene            613..683
                     /locus_tag="VYO11_001358"
     tRNA            613..683
                     /locus_tag="VYO11_001358"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:645..647,aa:Trp,seq:cca)
     gene            698..770
                     /locus_tag="VYO11_001359"
     tRNA            698..770
                     /locus_tag="VYO11_001359"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:731..733,aa:His,seq:gtg)
     gene            781..852
                     /locus_tag="VYO11_001360"
     tRNA            781..852
                     /locus_tag="VYO11_001360"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:813..815,aa:Gln,seq:ttg)
     gene            862..945
                     /locus_tag="VYO11_001361"
     tRNA            862..945
                     /locus_tag="VYO11_001361"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:896..898,aa:Leu,seq:caa)
     gene            complement(1056..1787)
                     /locus_tag="VYO11_001362"
     CDS             complement(1056..1787)
                     /locus_tag="VYO11_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001074368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HEV1595917.1"
                     /translation="MAKLYAISDIHGYLDEFRDALNKVNLNDKDNRLFLLGDYLDNGL
                     QSFQVISKIIELEEVYPNQIITLLGNHEEWFYDWLILDKPTASAFPETIKSFFSPEEL
                     NYIFKSNANNFETGVRNEIKNNIKFNPFINWFKKRYRDKRYYETDTQIFVHAGIDEEA
                     GKLWKELTSSEIFTNKFPITTGRFHKAIISGHIASWEVAKDRRYLGKIYYDSKSHYFI
                     DGDVTNSKTIPILCYDTITQKYHFL"
     gene            complement(1780..2016)
                     /locus_tag="VYO11_001363"
     CDS             complement(1780..2016)
                     /locus_tag="VYO11_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001058278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribbon-helix-helix protein, CopG family"
                     /protein_id="HEV1595918.1"
                     /translation="MNNVVTTQISIQLSQELNSLLNAIVEENNTTKTDFIRQAVIEKI
                     EDMYDIKVADEAYKKWVECGKKAISHEEMMRRYG"
     gene            complement(2232..2669)
                     /locus_tag="VYO11_001364"
     CDS             complement(2232..2669)
                     /locus_tag="VYO11_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEV1595919.1"
                     /translation="MDTSQVIKAHEVAKKAHFGQIDRAGIDYIKHPETVASFVATDEE
                     KAVAYLHDVIEDTSLTLLDLKKEGFSKNIIEAVDILTKKKGQDYQSYLNLVKKNELAR
                     VVKLADLRHNSDLTRLPLITEKDLERNKKYSSAIRFLRAKKKS"
     gene            complement(2710..3321)
                     /locus_tag="VYO11_001365"
     CDS             complement(2710..3321)
                     /locus_tag="VYO11_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEV1595920.1"
                     /translation="MQFWTVKEFQKFLTLFEPEEYNIKLLFTVLFFTGLRLGEALALT
                     WQDIDFSSNTIHITKSVYVNKGVTHISTTKTKAGTRRIVINKKLSQELQDWEKRQKHL
                     LEQFTNNSLTLQVFQNSPITITKNAIEKQYKKIIERDSTLKKIRIHDFRHSHASLLIN
                     QGEDYLVVKERLGHASITTTIDTYSHLYPSKQKDLADKLDDLL"
     gene            complement(3282..3369)
                     /locus_tag="VYO11_001366"
                     /pseudo
     CDS             complement(3282..3369)
                     /locus_tag="VYO11_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001850086.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="integrase"
     gene            complement(3364..3945)
                     /locus_tag="VYO11_001367"
                     /pseudo
     CDS             complement(3364..3945)
                     /locus_tag="VYO11_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269870.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
     gene            complement(4112..4501)
                     /locus_tag="VYO11_001368"
     CDS             complement(4112..4501)
                     /locus_tag="VYO11_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006268423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1595921.1"
                     /translation="MQTFNYDDFKNEKGIVSFSEAEQIYSSLLNSSNQLDKEFQEEWT
                     TFVLLCVEYASARGKWLTLSREEKLANDESRTVTHNKVIYQLKILKGLASEQGNDVAW
                     FEQFNDDRKRIGDFACYVAYIYALNAR"
     gene            complement(4659..5342)
                     /locus_tag="VYO11_001369"
     CDS             complement(4659..5342)
                     /locus_tag="VYO11_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000475577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsK"
                     /protein_id="HEV1595922.1"
                     /translation="MFKLRQSADLTRNNIISCYKLKIMHWLILSISACILFSTIVNIR
                     APTFVQILFIFLGGFIIYKIHLKIKIFRYDLEHYLIIRESLLYVLHTNRLYTTYKDST
                     GQEKVIRSAILEYELDRQKGHVLIKALIRGDEFSHKLKSLEDELCGVLELELEKKVLR
                     PSVAEYHFYYIKPKRLVLQSHNQRQEIDSLDIDLGYGVNYNPIKCPHILVSGGTGRGK
                     SVFISFLIA"
     gene            complement(5348..5566)
                     /locus_tag="VYO11_001370"
     CDS             complement(5348..5566)
                     /locus_tag="VYO11_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001282606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1595923.1"
                     /translation="MSDNLKAYIFLLGFLILAGIAIFILPQGHFFSVSALVLGCIPLF
                     ISIYYFAKIKLLGFYELLKELLDKIKGI"
     gene            complement(5596..6354)
                     /locus_tag="VYO11_001371"
     CDS             complement(5596..6354)
                     /locus_tag="VYO11_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000721212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HEV1595924.1"
                     /translation="MKKIKASTWNINQRSGQGKQIPEMIVHELAKQNSEIVCLTEYVK
                     TDNPSLFCTKLQDMGYKIFEDVRTIDFGNQILIAIKNDLVNDCQVITIDNDDNNPNFL
                     HVRVTIEGQELNIIGVRIKVGGENIFQDFKHRKSQLDKLISNLPATHENTIVLGDFNN
                     GYFQQNDDIHSYQGKAREFYSYPLLKSEMNKAGLTVHTPSEETSWKYCKLDHIFANIP
                     ISNENYSWEFLKNADYNSRVGFPDHAILSASISL"
     gene            complement(6372..6604)
                     /locus_tag="VYO11_001372"
                     /pseudo
     CDS             complement(6372..6604)
                     /locus_tag="VYO11_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000982220.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            6887..7348
                     /locus_tag="VYO11_001373"
     CDS             6887..7348
                     /locus_tag="VYO11_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1595925.1"
                     /translation="METRNEKFRRLSEARMTKVFSILNILRNQSDKSKYTFSKSDIEE
                     LFGALEQKGEEIKEFFTSPITIKTINLKKSFHYSMVDTSNDKEVAFKKLSTARVEKIF
                     SLMNLLANLSNKSNYNYSDWEVEELFSAYDEEVRKCKVFFEEKRTVFKYSE"
     gene            7624..8901
                     /locus_tag="VYO11_001374"
     CDS             7624..8901
                     /locus_tag="VYO11_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamylcysteine synthetase"
                     /protein_id="HEV1595926.1"
                     /translation="MSCSIDLLKHRYLKNIKENPELFVGIELEYPVASLEGDATDVEV
                     IKDLFHYLVSTLDLTVAKVDDFGNLIQLVDPISQDAILFEVSYTTIEFAFGKAETIQE
                     VENRFNNYMNVIQRKLAESNHAIVGCGIHPNWDKNENCPVAYPRYQMLMDYLNLSRNI
                     IKSDLHHFPEYGTFICGSQVQLDISKTNYLRVINAFTQIEAAKAYLFANSEFSGADWD
                     TKISRDIFWEESMHGIYPENVGVNARLLNDEADFFDYLNHSAIFTAERDGQTYYFYPI
                     QAGDYLATPEIQAFALNGDEVIISPQEKDFETHRSYQYQDLTTRGTVEFRSVCTQPLD
                     RTFASAAFHLGLLVNLDKLEAYLETAPFFKVFGYDYKFLRRQFSKKNLTDEEETTIIE
                     FSKDLLLLAEEGLVVRNKEEMTYLQPLREELSL"
     gene            8977..10461
                     /locus_tag="VYO11_001375"
     CDS             8977..10461
                     /locus_tag="VYO11_001375"
                     /EC_number="4.2.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006595200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="HEV1595927.1"
                     /translation="MTLVYQSTRDANNTVTASQAILQGLATDGGLFTPVTYPKVDLDF
                     DKLKDASYQEVAKLVLSAFLDDFTAEELDYCINNAYDSKFDTPAIAPLVKLDGQYNLE
                     LFHGSTIAFKDMALSILPYFMTTAAKKHGLENKIVILTATSGDTGKAAMAGFADVPGT
                     EIIVFYPKDGVSKIQELQMTTQTGDNTHVIAIDGNFDDAQTNVKHMFNDVALCEKLTT
                     NKLQFSSANSMNIGRLVPQIVYYVYAYAQLVKTGEIVAGDKINFTVPTGNFGNILAAF
                     YAKQIGLPVGKLICASNDNNVLTDFFKTRVYDKKREFKVTTSPSMDILVSSNLERLIF
                     HLLGNNAEKTAELMNALNTQGQYKLTDFDAEILDLFAAEYATEEETAAEIKRVCELDS
                     YIEDPHTAVASAVYKKYQSATGDVTKTVIASTASPYKFPVVAVEAVTGKAGLTDFEAL
                     AQLHEISGVAVPPAVDGLEIAPVRHKTTVAAADMQAAVEAYLGL"
     gene            10522..11802
                     /locus_tag="VYO11_001376"
     CDS             10522..11802
                     /locus_tag="VYO11_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000473957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HEV1595928.1"
                     /translation="MFKKNKDILNIALPAMGENFLQMLMGMVDSYLVAHLGLIAISGV
                     SVAGNIITIYQAIFIALGAAISSVISKSIGQKDQSKLAYHVTEALKITLLLSFLLGFL
                     SIFAGKEMIGLLGTERDVAESGGLYLSLVGGSIVLLGLMTSLGALIRATHNPRLPLYV
                     SFLSNALNILFSSLAIFVLDMGIAGVAWGTIVSRLVGLVILWSQLKLPYEKPTFGLDK
                     ELLTLALPAAGERLMMRAGDVVIIALVVSFGTEAVAGNAIGEVLTQFNYMPAFGVATA
                     TVMLLARAVGEDDWKRVASLSKQTFWLSLFLMLPLSFSIYVLGVPLTHLYTTDSLAVE
                     ASVLVTLFSLLGTPMTTGTVIYTAVWQGLGNARLPFYATSIGMWCIRIGTGYLMGIVL
                     GWGLPGIWAGSLLDNGFRWLFLRYRYQRYMSLKG"
     gene            11806..12426
                     /locus_tag="VYO11_001377"
     CDS             11806..12426
                     /locus_tag="VYO11_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001172828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEV1595929.1"
                     /translation="MQKTAFIWDLDGTLLDSYEAILSGIEETFAQFSIPYDKEKVREF
                     IFKYSVQNLLVRVAEDRNLDVEVLNQVRAQSLAEKNAQVVLMPGAREVLAWADESGIQ
                     QFIYTHKGNNAFTILKDLGVESYFTEILTSQSGFVRKPSPEAATYLLDKYQLNSDNTY
                     YIGDRTLDVEFAQNSGIQSINFLESTYEGNHRIQALADISRIFETK"
     gene            12592..13734
                     /locus_tag="VYO11_001378"
     CDS             12592..13734
                     /locus_tag="VYO11_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEV1595930.1"
                     /translation="MKKRMLLASTVALSFAPVLATQAEEVLWTARSVEQIQNDLTKTD
                     NKTSYTVQYGDTLSTIAEALGVDVTVLANLNKITNMDLIFPETVLTTTVNEAEEVTEV
                     EIQTPQADSSEEVTTATADLTTNQVTVDDQTVQVADLSQPIAEAPKEVASSSEVTKTV
                     IASEEVAPSTGTSVPEEQTAETTRPVEEATPQETTPAEKQETQASPQAASAVEATTTS
                     SEAKEVASSNGATAAVSTYQPEETKVISTTYEAPAAPDYAGLAVAKSENAGLQPQTAA
                     FKEEIANLFGITSFSGYRPGDSGDHGKGLAIDFMVAERSELGDKIAEYAIQNMASRGI
                     SYIIWKQRFYAPFDSKYGPANTWNPMPDRGSVTENHYDHVHVSMNG"
     gene            14140..14478
                     /locus_tag="VYO11_001379"
     CDS             14140..14478
                     /locus_tag="VYO11_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HEV1595931.1"
                     /translation="MTRYQILLFLLEHSPCNQMAVQERLKIDQAALTRHFKILETEGL
                     VERHRNPENQREVLVEAAKYAKEQLVVNPPLQHIKVKEEMESILTEFERTELSRLLNK
                     LVLGIENIEI"
     gene            14489..14847
                     /locus_tag="VYO11_001380"
                     /pseudo
     CDS             14489..14847
                     /locus_tag="VYO11_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861952.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 domain-containing protein"
     gene            14954..15571
                     /gene="pcp"
                     /locus_tag="VYO11_001381"
                     /pseudo
     CDS             14954..15571
                     /gene="pcp"
                     /locus_tag="VYO11_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
     gene            complement(15599..16456)
                     /locus_tag="VYO11_001382"
     CDS             complement(15599..16456)
                     /locus_tag="VYO11_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HEV1595932.1"
                     /translation="MNYPKIDLKTIRQESKHFQADTPRLFLLYILPSMLVILSSFLNP
                     LSRIHGTVLEQPFFSILGQILQTYLFPLLVSFIGTILLTSSVYATLTLMKDSKTEPSV
                     KNSLALFDEERFSQTFLTLLLKRFYLFLWSIPNLLGIYLLFYSSFLAKKFVTLHPEFP
                     NLDLSSVETERFLMVFGLYFLASLILIIVGNILYIPQYYAYSQVEFLLCYSLDLGQVP
                     PRRILKTSRSFMKGYKFQRFVLDLQLLPWYFLNWITFGIASFSLLPYIQCTKIMFYRA
                     VLARKRPKA"
     gene            16586..17728
                     /gene="tgt"
                     /locus_tag="VYO11_001383"
     CDS             16586..17728
                     /gene="tgt"
                     /locus_tag="VYO11_001383"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HEV1595933.1"
                     /translation="MSDSPIKYRLIKKEKHTGARLGEIITPHGTFPTPMFMPVGTQAT
                     VKTQSPEELKEMGSGIILSNTYHLWLRPGDELIARAGGLHKFMNWDQPILTDSGGFQV
                     YSLADSRNITEEGVTFKNHLNGSKMFLSPEKAISIQNNLGSDIMMSFDECPQFYQPYD
                     YVKKSIERTSRWAERGLKAHRRPHDQGLFGIVQGAGFEDLRRQSAHDLVSMDFSGYSI
                     GGLAVGETHEEMNAVLDFTTQLLPENKPRYLMGVGAPDSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAQFAEDFTPLDPECDCYTCNNYTRAYLRHLLKADETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFREYFVEKYGYNKSGRNF"
     gene            17826..19643
                     /locus_tag="VYO11_001384"
     CDS             17826..19643
                     /locus_tag="VYO11_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HEV1595934.1"
                     /translation="MRIKWFSLVRITGLLLVLLYHFFQTIFPGGFFGVDVFFTFSGFL
                     ITALLIEEFSKNHEIDLIGFFRRRFYRIVPPVVLMVLVTMPFTFLVRQDYVAGIGGQI
                     ASVLGFMTNFYELLTGGSYESQFIPHLFVHNWSLAVEVHYYILWGLAVWFLSKQAKSN
                     GQLKGIVFLLSAVAFLISFFSMFIGSFLVTSYSSVYFSSLTHVYPFFLGSMLATIVGV
                     RQTTSLVKQLDKIWDLRKTLVVFGGGFGFLVLLTFFVKFTYLFAYLIGFLLASLAALA
                     MILAARVLHEKTHHIQEPKIISFLADTSYAVYLFHWPFYIIFSQLTSNLLAVLLTLIC
                     SYGFASLSFYVLEPWIAGKNTPILQTLRPLPYIHAILVAGTGILTIIVCTVTLLAPQV
                     GAFETDLTVNGLKQAATNIGQTKVMAERADANSLGIADGTMLIGDSVALRANTALQTA
                     LPGAQINAQVSVTTKTANEIMLNNSQNKFLPKTVVIATGVNNPENYKDDWDSIVKNLP
                     KGHHMILVTPYEGDKTKETYAIVEKAAAYMRELAEKTPYITIADWNQVAKEHPEIWAG
                     TDQVHFGSESSTIEAGAKLYADTIATALQTAQDKPVKSK"
     gene            19796..20947
                     /gene="nagA"
                     /locus_tag="VYO11_001385"
     CDS             19796..20947
                     /gene="nagA"
                     /locus_tag="VYO11_001385"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HEV1595935.1"
                     /translation="MPNYIKADQFFYPHGVRRGGYLELVDGKFGKHVEQIPEGAEVID
                     YTGYSIAPGLVDTHIHGYAGVDVMDNNIEGTLHTMSEGLLSTGVTSFLPTTLTATYEQ
                     LLAVTENLGNHYKEATGAKIRGIYYEGPYFTETFKGAQNPTYMRDPGVEEFHSWQKAA
                     NGLLNKIALAPERDGVEDFVRTVTGEGVTVALGHSNATFDEAKKAVDAGASVWVHAYN
                     GMRGLTHRELGMVGAMYQLPHTYAELICDGHHVDPKACEILIKQKGTENIALITDCMT
                     AGGLEDGDYMLGEFPVVVANGTARLKSTGNLAGSILKLKDGLKNVVEWGIANPHEAVM
                     MASFNPAKSVHIDDVCGQIREGYDADFIVLDKDLELVATYLDGVKRYQA"
     gene            21110..22168
                     /locus_tag="VYO11_001386"
     CDS             21110..22168
                     /locus_tag="VYO11_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent alcohol dehydrogenase family
                     protein"
                     /protein_id="HEV1595936.1"
                     /translation="MKAYTYVKPGLASFVDVDKPVIRKPTDAIVRIVKTTICGTDLHI
                     IKGDVPTCQSGTILGHEGIGIVEEVGEGVSNFKKGDKVLISCVCACGKCYYCKKGIYA
                     HCEDEGGWIFGHLIDGMQAEYLRVPHADNTLYHTPEDLSDEALVMLSDILPTGYEIGV
                     LKGKVEPGCSVAIIGSGPVGLAALLTAQFYSPAKLIMVDLDDNRLETALSFGATHKVN
                     SSDPEKAIKEIYDLTDGRGVDVAIEAVGIPATFDFCQKIIGVDGTVANCGVHGKPVEF
                     DLDKLWIRNINVTTGLVSTNTTPQLLKALESHKIEPEKLVTHYFKLSEIEKAYEVFSK
                     AADHHAIKVIIENDISEA"
     gene            complement(22213..>22378)
                     /locus_tag="VYO11_001387"
     CDS             complement(22213..>22378)
                     /locus_tag="VYO11_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV1595937.1"
                     /translation="LPYSNAKLEATNNLIKLIKRNAFGFRNFENFKKRIFIALNIKKK
                     GRILSFLELS"
BASE COUNT         6664 a         3859 c         4728 g         7127 t
ORIGIN      
        1 tttagcgggt gtagtttagt ggtaaaacta cagccttcca agctgttgtc gcgagttcga
       61 ttctcgtcac ccgctttgaa ctttgttctt tgtaccaagt ttttgacttg ggcgcgtagc
      121 tcaggtggtt agagcgcacg cctgataagc gtgaggtcgg tggttcgagt ccactcgtgc
      181 ccatagtgtt tagtccatta ctaggggatt ggaatattat ctgttcacta agaggacacg
      241 ggcttgttcc cgtataaact attttggagg attacccaag tccggctgaa gggaacggtc
      301 ttgaaaaccg tcaggcgtgt aaaagcgtgc gtgggttcga atcccacatc ctccttttat
      361 attaacgcgg gatggagcag ctcggtagct cgtcgggctc ataacccgaa ggtcgtaggt
      421 tcaaatcctg ctcccgcaat aaggctcggt agctcagttg gtagagcaat ggattgaagc
      481 tccatgtgtc ggcggttcga ttccgtctcg cgccatttat atattttgga agggtagcga
      541 agaggctaaa cgcggcggac tgtaaatccg ctccttcggg ttcgggggtt cgaatccctc
      601 cccttccatt ttacgggcat agtttaaagg tagaactaag gtctccaaaa ccttcagtgt
      661 gggttcaatt cctactgccc gtgttaatag aattatggcg ggtgtggtga agtggttaac
      721 acaccagatt gtggctctgg catgcgtggg ttcgatcccc atcactcgcc tattttatat
      781 tggggtatag ccaagcggta aggcaaggga ctttgactcc ctcatgcgtt ggttcgaatc
      841 cagctacccc agttactatt tgccggcgtg gcggaattgg cagacgcgct ggactcaaaa
      901 tccagtgtcc gcaaggacgt gccggttcga ccccggccgc cggtatagtt gaaaagacaa
      961 ggtttctaag ccttgtcttt ttgttatgtc ataagaaatt tcttggaatt gttactaata
     1021 attactaatt tcatataaaa gcacatgatt aaaagttata gaaagtgata tttttgggta
     1081 attgtatcat agcaaagaat aggtattgtt ttgctattcg ttacatctcc atcaataaaa
     1141 taatgacttt tactatcata gtaaatctta cccaggtatc ttctatcttt agctacttcc
     1201 caagaagcaa tatggcccga aataatagct ttatgaaatc taccagtggt aataggaaat
     1261 ttgtttgtaa atatctctga actcgttagt tctttccaaa gctttccggc ttcttcatca
     1321 atgccagcat gaacaaaaat ttgggtatca gtttcataat agcgtttatc cctatatcgt
     1381 tttttaaacc agtttataaa tggattgaat ttgatattat ttttaatttc atttctaaca
     1441 cctgtttcaa agttgttagc attcgattta aaaatatagt tcaattcctc tggagagaag
     1501 aagcttttta ttgtttctgg aaatgctgaa gcagtaggct tatctaaaat caaccaatca
     1561 taaaaccatt cttcatgatt ccctagaaga gtaataattt gattaggata aacttcctca
     1621 agttcgatta ttttggaaat gacttgaaaa gattgaagtc cattatcaag ataatctcct
     1681 agtaaaaata ggcgattatc tttatcgttt aaatttactt tattgagagc gtctctgaat
     1741 tcatccaagt atccatgtat atcagatatt gcgtataatt tagccatagc gtctcatcat
     1801 ttcttcatgt gagatagctt ttttgccaca ttcaacccat tttttataag cttcatcagc
     1861 gaccttaata tcatacatat cttcaatttt ctctataaca gcttgtctaa taaagtcagt
     1921 ctttgttgta ttattttctt caacaatagc atttaataaa gaatttaact cttgactaag
     1981 ttgaatagaa atttgtgtag taacaacatt attcatataa cagccaccta atagttattt
     2041 tagatacatt atactcctag tctaaaagtt tctcaataaa aaatttcact ttttatagtt
     2101 atttatttta ataaaattgt agtatctgca aggatgtgcc agttcgagac cgaccgccag
     2161 tatagtaata aagacaaagt ttataagcct tgtcttttgt tttctcttta taaaatttta
     2221 tagtttagtt actaactttt tttctttgct cttaaaaatc taatagcaga actgtatttc
     2281 ttatttctct ctaagtcttt ttcagtaatt aatggtagtc ttgttaaatc tgaattatgc
     2341 cgtaaatccg ccaactttac aactctagcg agttcatttt tctttactag attgagataa
     2401 gattgataat cttgtccttt tttctttgtg agtatatcga cggcttctat aatgtttttt
     2461 gaaaaacctt ccttttttag gtctagtagg gttagtgaag tatcttcaat tacatcatgt
     2521 agataggcga cagctttctc ttcatcagtt gcgacaaaac tagctactgt ttcagggtgt
     2581 ttaatgtagt caattcctgc tctatcaatt tgtccaaagt gtgctttttt agctacttca
     2641 tgtgctttta ttacttgtga tgtatccatg atttaattat aaactttcca tttataaaac
     2701 tcaattactt tatagtaaat catctagttt atcagctaaa tccttttgct tacttgggta
     2761 caagtgagag taggtatcaa tcgtggttgt tatagaagca tgtcctagtc gctcttttac
     2821 aactagataa tcttcccctt ggttaatcag cagggaagcg tgtgagtgcc taaaatcgtg
     2881 tatgcgtatc ttttttagtg tgctatcacg ttcaatgatt ttcttgtact gcttttcaat
     2941 agcatttttc gtaattgtga taggactatt ttgaaacact tgtaatgtta ggctattgtt
     3001 ggtaaattgc tctaatagat gtttttgtcg cttttcccaa tcttgtaatt cttggcttaa
     3061 ttttttattg ataacaattc ttcttgttcc tgctttagtt tttgttgtgc tgatatgagt
     3121 tactccttta ttaacataga cagatttcgt gatatgaatt gtattacttg aaaagtcgat
     3181 gtcttgccat gttagggcaa gagcttcccc aagtcttaat cctgtaaaga atagaacagt
     3241 aaagagtagt ttgatattgt attcttcggg ttcaaatagt gtcaaaaact tctgaaattc
     3301 tttgactgtc caaaattgca tttttgtttt ttcaattggc aactttttta tcaattttgc
     3361 tggaggggta tgtccaacaa tttgtttagg aaagtcttgg ttgggaagca gttctaattc
     3421 tctaaaatgt gcccataaag gagaaccccc aagagctttc ccaccacgca ttggtcctat
     3481 tgtataagct agaatatcta attcttcttc atgctctttg gtatagaggt taaaatgcca
     3541 ttcttttggg tcaaatatca gattgaaacc agcatggcta actaaataat catctagttg
     3601 ataagctact tgtaaattca aatcttgtaa taattgttga attgcgaaaa agacctctag
     3661 attttgaatt gagaaaggag cttgttctcc cagtaaataa taagcatcat gattacctat
     3721 aagattaatt acatctattc cattttgctc tttatctatt ttccaagagt ataaaaaagt
     3781 gaggtctttg gcataaagtt ggatattgtt agtttgacca tgtaaatcaa cgtagtcacc
     3841 aagaaaaatg attctcttaa tattatgtgt ttggataatt ttgtcaacaa tgggtaaaat
     3901 cagttgagat tttaagtgta aatcaccaat taataacgtc ttcatatata ttcccctctt
     3961 tatttttgat attagtctaa gaatcgaatt aagttatagc acattgtttc ggtgatagat
     4021 aaaaagaatt aattattctt aagatgttat ttaataattt ccatgaatat cagaaataga
     4081 gtaatatata gccataatat cctctaattg tctatcgagc atttaaggca tagatataag
     4141 ctacatagca agcaaagtcg ccaatacgtt ttctgtcatc gttaaattgt tcaaaccaag
     4201 caacatcatt gccctgttca cttgctaaac cttttaaaat ctttagttga taaataactt
     4261 tattgtgagt aacagttcta gattcatcat tggcaagttt ctcttctctt gagagtgtga
     4321 gccatttacc acgtgcagag gcatactcta cgcatagaag tacaaatgtt gtccattctt
     4381 cttgaaattc tttatcaagt tgattggagg aattaaggag actagaatag atttgttctg
     4441 cttcagaaaa tgaaacaatc cccttttcat tcttaaaatc atcgtagtta aaagtttgca
     4501 ttgtaaaact cctttatata ttatctaatc ttagctattt tgttacaggt aaaacatcag
     4561 aacaagcgaa ccacaagttt ccattgaatt gccctacatt taaatcttta agagtaacag
     4621 gacaagtttt gttgttcgcc atctcttgaa cagaagcact aggcgatcag gaaagatatg
     4681 aagacagact ttcctctccc tgtccctcct gatactaaaa tatgtgggca tttgattggg
     4741 ttataattta caccatatcc taaatctata tcaaggctat ctatctcttg tctttggttg
     4801 tgagattgta gaactaacct ttttggtttt atgtaataga aatgatactc tgcaacacta
     4861 ggccgaagaa cctttttctc aagctctagt tcaagcacgc cacaaagttc atcttcaaga
     4921 gatttaagtt tgtggctaaa ctcgtcccct cttataagag ccttgataag tacatgacct
     4981 ttctgtctat ctaattcata ttctaagatt gcacttctaa taactttttc ttgtccagta
     5041 ctatctttat atgtagtata aagtctattt gtgtggagta cataaagtaa gctctcacgt
     5101 ataataaggt aatgctctaa gtcatatcga aaaattttta ttttcagatg aattttatag
     5161 ataataaatc cacctaaaaa tatgaagaga atttgaacaa aagttggagc cctaatatta
     5221 acaatagtag aaaatagaat gcaggcagag atacttagta tcagccagtg cattattttt
     5281 agcttataac aggaaattat attgtttctt gttaaatcag cactttgtct taatttaaac
     5341 atattagtta gatacctttt attttatcta aaagctcttt taaaagttcg taaaacccta
     5401 agagcttgat ttttgcgaaa taatagatag aaataaataa tggaatacat ccaagaacaa
     5461 gggcagaaac tgaaaagaaa tgcccttgag gaagaataaa aattgctatg ccagctaata
     5521 tcagaaatcc taaaagaaat atatatgctt ttaaattatc actcattttg cattacctcc
     5581 tctaataaac aagtactata aagagataga ggctgataga atagcatggt ctggaaagcc
     5641 gactcggcta ttataatcag cattttttaa gaattcccaa gaataatttt catttgatat
     5701 aggaatgttt gcaaaaatat ggtctaattt acaatatttc caagaggttt cctcagaggg
     5761 agtatgtacg gttaggcctg ctttattcat ttcagactta agcaatggat aagagtaaaa
     5821 ctccctagct ttgccctgat aggaatgaat atcgtcattc tgttggaaat atccattatt
     5881 aaagtcaccc agcacaattg tattttcatg tgttgcgggt aaatttgaga ttagtttgtc
     5941 tagttgcgat tttcgatgtt tgaaatcttg aaaaatgttt tctccaccga ccttgatacg
     6001 aactccaata atgtttaatt cttgtccttc aattgtcact ctaacgtgta aaaagtttgg
     6061 attattatca tcattatcga tagtaatgac ttggcaatca ttaactaaat cattctttat
     6121 tgcaataagg atttgatttc caaaatcaat agtacgcaca tcttcaaaaa ttttgtatcc
     6181 catatcctgt aatttagtac agaataaact aggattatct gtttttacat attctgtcaa
     6241 gcagacgatt tctgaatttt gtttagctaa ttcatgtaca atcatttcag gaatttgttt
     6301 tccttgtcct gaacgttgat tgatattcca agtggatgct ttaatttttt tcatatataa
     6361 acctttctat gttctgcttt actaacgtaa agaagattta ttagatgatt gtttgcaata
     6421 acaaggtaaa caagatttcc tgttctggtt tcatactcat ttactagctc tctataatgt
     6481 gctttatcag tgtctatttt tcccattgat tagtgagact agggctgagt gcaaaaacgg
     6541 tatcaagagt atctaatcta tctcgtgctt cttgatattg ttcagttttt aatgtattca
     6601 tcattttgtc ctctctttaa tgttaattga gggagcaaat gctcctgtgt gatgtatgag
     6661 tgaaatgagg aagtgctaga agttgtatcc atcatagatt tctccaagtt ctgtaaatat
     6721 aagaatcctc ctttttgtat agtatatttg cgggatattc ccctatgttt ggtattatac
     6781 tacagttaaa taaaaaaatc aacaacaaag atgcaatatt tgaaaaaaat ctctccatat
     6841 gataaaattt aatgtatagc aatggtaggt aatgttagga gaaacaatgg aaactagaaa
     6901 tgaaaaattt agaagattat cagaagctag aatgactaag gttttttcaa ttttaaatat
     6961 attgagaaat caaagtgaca aatcgaaata cactttttca aaatcagaca ttgaggagct
     7021 atttggagcg ttagaacaaa aaggtgaaga aataaaagag tttttcacta gccctattac
     7081 gataaaaaca atcaatctaa aaaaatcttt tcattattct atggttgata caagtaatga
     7141 taaggaagta gcttttaaga aattatcaac tgcaagggta gaaaaaattt tttcactaat
     7201 gaatttactt gcaaatctta gcaataaatc gaattataat tatagtgatt gggaagtgga
     7261 agaattgttt tcagcttatg atgaagaagt aagaaaatgc aaagtatttt tcgaagaaaa
     7321 gagaacagta tttaaatata gtgaataagt caggaatact aaagtgttac taaaaataaa
     7381 aaaactatcg tttttgtgat agaggtaact ttttgaaaag gctatttgac tggctttata
     7441 tacttatgaa atgttaagag cccaactcaa aatccagtgt ccgcaaggac gtgccggttc
     7501 gaccccggcc gccggtatag tatagtgtta ggaacgttgt tattcttcgt tcctttttta
     7561 tattattttt ggtataatta tagttattca aattttattt agattaagaa agtgtagggg
     7621 agtatgtctt gttctatcga tttattaaaa catcggtatt tgaaaaatat taaagaaaat
     7681 cctgaattgt ttgtcggaat tgagttggag tatcctgttg caagtttaga aggggatgct
     7741 acagatgttg aagttataaa ggatctattt cattatttag tttctacttt ggatctcacc
     7801 gtagcaaagg tagatgattt tggcaatctg atccagttag tagatccgat aagtcaggat
     7861 gctattttat ttgaagtttc ctatacaacg attgagtttg catttggtaa ggctgaaacg
     7921 attcaagagg tcgaaaatcg tttcaataat tatatgaatg taattcagag aaagttagct
     7981 gaatcaaatc atgctattgt tggctgtggt atccatccca actgggataa aaatgagaat
     8041 tgtccagtgg cttatccacg ctatcagatg ttgatggatt atttgaattt gagtagaaat
     8101 attattaaat cagatttaca tcatttccct gaatatggta cttttatctg tgggagccag
     8161 gttcagctgg atatttcaaa aaccaactac ttacgggtga ttaatgcttt tactcaaatt
     8221 gaagcggcta aggcttattt atttgcaaac tctgagtttt cgggtgcgga ttgggatacg
     8281 aaaatttcaa gggatatttt ctgggaagaa tctatgcatg gtatctatcc agagaatgtt
     8341 ggggtcaatg ctagactcct taatgatgaa gctgattttt ttgactatct aaatcattct
     8401 gcgattttta ctgcggaacg tgatgggcag acctattatt tttatcctat tcaggctggg
     8461 gactatttgg ctacgcctga aatccaagca tttgctctga atggggatga ggttattatt
     8521 tccccccaag agaaggattt tgaaactcat cgtagttacc agtaccaaga cttaacgact
     8581 cgaggaacag ttgagtttcg tagtgtgtgt acacagccac ttgataggac ttttgcttct
     8641 gcagcttttc acttgggatt attggttaat ttagacaagt tagaagctta cttagaaaca
     8701 gcacctttct ttaaagtatt tggttatgat tacaagtttt taaggagaca attttctaag
     8761 aaaaatctta cagatgagga agaaactacg attattgaat tttccaaaga cttactccta
     8821 ctagctgagg agggactagt ggtgagaaat aaggaagaaa tgacctattt acagcctttg
     8881 agagaagaat tgagcctata atttctctta taaagggaga attttctgaa aaatcatgat
     8941 ataatggacg agactataga taaaggatag agagtaatga cattagttta tcaatcaacg
     9001 cgtgatgcca acaatacagt aactgccagc caagcaattt tgcaaggttt ggcgacggac
     9061 ggcggtttgt ttacaccggt tacttatcca aaggtagatt tggactttga caaattgaaa
     9121 gatgcttctt atcaggaagt tgctaagcta gttttgtcag catttttaga tgactttaca
     9181 gctgaggagt tggactactg tatcaacaat gcctacgata gcaaatttga tactccagct
     9241 attgcaccat tagtgaaatt agatgggcaa tacaatttgg aacttttcca tggttcaacg
     9301 attgccttta aggatatggc cttgtctatt ttgccatact ttatgacgac tgctgctaag
     9361 aaacatggtt tggagaacaa gattgttatc ttgacagcga catctggtga cacggggaaa
     9421 gctgctatgg cggggtttgc ggatgtgcct ggtactgaga ttatcgtctt ttatccaaag
     9481 gatggtgtca gcaagattca agagttacaa atgaccactc aaactggcga caatactcat
     9541 gttattgcta ttgatggtaa ctttgacgat gcgcaaacaa atgtgaagca catgtttaac
     9601 gacgtggctc tttgtgaaaa attgactacc aacaagttgc aattttcatc agctaactct
     9661 atgaacattg gtcgtctggt gccacagatt gtttattatg tttatgccta tgctcagttg
     9721 gtcaagactg gtgagatcgt ggctggtgat aagattaact tcacagtacc aacaggaaac
     9781 tttggaaata tcttggctgc cttttatgcc aaacaaattg gtttgccagt tggtaaatta
     9841 atctgtgctt caaatgacaa taatgtcttg acagacttct ttaaaacacg tgtctatgac
     9901 aaaaaacgtg agtttaaggt aacaaccagc ccatctatgg atatcttggt atcttcaaac
     9961 ttggagcgct tgattttcca tcttttggga aataatgctg aaaagacagc tgaacttatg
    10021 aatgccttga acacgcaagg acaatataag ttgacagact ttgatgcaga gattttggac
    10081 ctctttgcag ctgaatatgc gactgaggaa gaaacggcag cagagatcaa gcgtgtttgt
    10141 gagttagatt cttatatcga ggaccctcat acagctgttg cttcagcagt ttataaaaaa
    10201 taccaatcgg ccactggaga tgtaactaag acagtgattg cttcaacagc tagtccatac
    10261 aagttcccag tagttgcagt agaagctgta actggaaaag caggtttaac agactttgaa
    10321 gccttggctc aattacatga aatctcaggc gttgcagtgc caccagcagt tgatgggctt
    10381 gaaatagctc ctgttcgtca caagacaact gtagcggctg ctgatatgca agcagcggtt
    10441 gaggcttatt taggacttta agatagaggg agtaaactcg gttgggaaac caactgagtt
    10501 tcttttcatc aggaggagag attgtttaag aaaaataaag acattcttaa tattgcattg
    10561 ccagctatgg gtgaaaactt tttgcagatg ctaatgggaa tggtggacag ttatttggtt
    10621 gctcatttag gattgatagc tatttcaggg gtttcagtag ctggtaatat tatcaccatt
    10681 tatcaggcga ttttcatcgc tctgggagct gctatttcca gtgttatttc aaaaagcata
    10741 gggcagaaag accagtcgaa gttggcctat catgtgactg aggcgttgaa gattacctta
    10801 ctattaagtt tccttttagg atttttgtcc atcttcgctg ggaaagagat gataggactt
    10861 ttggggacgg agagggatgt agctgagagt ggtggactgt atctatcttt ggtaggcgga
    10921 tcgattgttc tcttaggttt aatgactagt ctgggagcct tgattcgtgc aacgcataat
    10981 ccacgtctgc ctctctatgt tagtttttta tccaatgcct tgaatattct tttttcaagt
    11041 ctagctattt ttgttctgga tatggggata gctggtgttg cttgggggac aattgtgtct
    11101 cgtttggttg gtcttgtgat tttgtggtca caattaaaac tgccttatga gaagccaact
    11161 tttggtttag ataaggaact gttgaccttg gctttaccag cagctggaga gcgacttatg
    11221 atgagggctg gagatgtagt gatcattgcc ttggtcgttt cttttgggac ggaggcagtt
    11281 gctgggaatg caatcggaga agtcttgacc cagtttaact atatgcctgc ctttggcgtc
    11341 gctacggcaa cggtcatgct gttggcccga gcagttggag aggatgattg gaaaagagtt
    11401 gctagtttga gtaaacaaac cttttggctt tctctgttcc tcatgttgcc cctgtccttt
    11461 agtatatatg tcttgggtgt accattaact catctctata cgactgattc tctagcggtg
    11521 gaggctagtg ttctagtgac actgttttca ctacttggga cccctatgac gacaggaaca
    11581 gtcatctata cggcagtctg gcagggatta ggaaatgcac gcctcccttt ttatgcgaca
    11641 agtataggca tgtggtgtat ccgcattggg acaggatatc tgatggggat tgtgcttggt
    11701 tggggcttgc ctggtatttg ggcagggtct ctcttggata atggttttcg ctggttattt
    11761 ctacgctatc gttaccagcg ctatatgagc ttgaaaggat aggaaatgca aaaaacagct
    11821 tttatttggg atttagacgg gactttattg gactcttacg aagcgatttt atcagggatt
    11881 gaggagactt ttgctcagtt ttctattcct tatgataagg agaaggtgag agagtttatc
    11941 ttcaagtatt cggtgcaaaa tttgcttgtg cgggtggcag aagatagaaa tctggatgtt
    12001 gaggtgctaa atcaggtgcg tgcccagagt ctggctgaga agaatgctca ggtagttttg
    12061 atgccaggtg cgcgtgaggt gctagcttgg gcagacgaat caggaattca gcagtttata
    12121 tatactcata aggggaacaa cgcttttacc attctcaagg acttgggggt ggaatcctat
    12181 tttacagaga ttttaaccag tcagagtggc tttgtgcgga agccaagtcc agaagcggct
    12241 acctatctgc tagataagta tcagttgaat tctgataata cttattatat aggggatcgg
    12301 actctggatg tggaatttgc ccagaatagt gggattcaaa gtatcaactt tttagagtct
    12361 acttatgaag ggaatcacag gattcaagcg ttagcagata tttcccgtat ttttgagact
    12421 aagtgataaa aagattgtgt cagttttgtg acagagacct aacaaactat ttcaagtaac
    12481 ctagtttgtt acaaggagta gacagttctg ttaaataggc ccgagagggc tttttttcta
    12541 cattttttgt gttatgatag acaggtactc atttgaaagg aatttgaaag aatgaagaaa
    12601 agaatgttat tagcgtcaac agtagccttg tcatttgccc cagtattggc aactcaagca
    12661 gaagaagttc tttggactgc acgtagtgtt gagcaaatcc aaaacgattt gactaaaacg
    12721 gacaacaaaa caagttatac cgtacagtat ggtgatactt tgagcaccat tgcagaagcc
    12781 ttgggtgtag atgtcacagt gcttgcgaat ctgaacaaaa tcactaatat ggacttgatt
    12841 ttcccagaaa ctgttttgac aacgactgtc aatgaagcag aagaagtaac agaagttgaa
    12901 atccaaacac ctcaagcaga ctctagtgaa gaagtgacaa ctgcgacagc agatttgacc
    12961 actaatcaag tgaccgttga tgatcaaact gttcaggttg cagacctttc tcaaccgatt
    13021 gcagaagctc caaaagaagt agcatcaagt tcagaagtta caaagacagt gattgcttct
    13081 gaagaagtgg caccatctac gggcacttct gtcccagagg agcaaacggc cgaaacaact
    13141 cgcccagttg aagaagcaac tcctcaggaa acgactccag ctgagaagca ggaaacacaa
    13201 gcaagccctc aagctgcatc agcagtggaa gcaactacaa caagttcaga agcaaaagaa
    13261 gtagcatcat caaatggagc tacagcagca gtttctactt atcaaccaga agaaacgaaa
    13321 gtaatttcaa caacttacga ggcaccagct gcgcccgatt atgctggact tgcagtagca
    13381 aaatctgaaa atgcaggtct tcaaccacaa acagctgcct ttaaagaaga aattgctaac
    13441 ttgtttggca ttacatcctt tagtggttat cgtccaggag acagtggaga tcacggaaaa
    13501 ggtttggcta tcgactttat ggtagcagaa cgttcagaat taggggataa gattgcggaa
    13561 tatgctattc aaaacatggc cagccgtggc attagttaca tcatctggaa acaacgtttc
    13621 tatgctccat tcgatagcaa atatgggcca gctaacactt ggaacccaat gccagaccgt
    13681 ggtagtgtga cagaaaatca ctatgatcac gttcacgttt caatgaatgg ataaacccga
    13741 cttgataaca tcattttgac gaatgagatc tagctttcgt gatggaaagc gattctcgtt
    13801 cgttttttct ttgtcatact cttcgaaaat ctcttcaaac cacgtcagtt ttatatgaaa
    13861 cctcaaagct gtgctttgag caacctgcga ctagcttcct agtttgctct ttgattttca
    13921 ttgagtatca atttgaatgg aaaatggaaa gttattatct tgtaataatc caagcaacat
    13981 tcttgcaatc tattttactt tatatcacaa ttgattggtc aactattgat aagtcaatgg
    14041 ataggaggaa gaaatgatag agattcaaga tttactgtat caactccgct tgtctgagca
    14101 agcgagtacg caattgtttg aaaaaggctt gggattagtt tgacacggta tcagatttta
    14161 ctgtttttgc tggagcattc tccttgtaac caaatggcgg ttcaggagcg tttgaaaatt
    14221 gatcaggctg ctttgacacg gcatttcaag attttggaaa cggaaggttt ggtggagcgt
    14281 catcgtaatc ctgaaaatca gcgggaagtg ttggtagagg ctgcgaagta tgccaaggag
    14341 cagttagtgg tgaatccccc tctgcaacat atcaaggtta aggaagagat ggaaagtatc
    14401 ttaacagagt ttgagagaac agaactcagc cgtttattaa ataaattggt tttgggtatt
    14461 gaaaatatag aaatttaagg agaaatagat gtcaattatt ttaacaacga tcgttgcttt
    14521 ggagcatttt tatatttttt atttggaaag tattgccacg caatcagatg cgactagtcg
    14581 tgtatttaat atggaaaagg aagaattggc tcatccgtca gtaagttcat tgttcaaaaa
    14641 tcaaggaatt tataaggctc tgctaggagt ctttctcttg tatgtcattt atttctcaca
    14701 gaatttagaa attgtgacta tttttgtctt atttgtgatt ggtgctgcga cttacggctc
    14761 tttaacagcg gataaaaaat tattttgaag caaggtggat cagctatttt ggccttgatt
    14821 agtattttac tctttaaata cacttgaagg ttgattctaa tctcgctaat cctttttaat
    14881 ccagaataag ggaaatatgt tatacttgtt tttaagaaaa aagtctcatt gaattggttt
    14941 tgaggagtta gaaatgaaag tattagtgac aggttttgag cccttttgag gccattaaag
    15001 gtttaccagc tgaaatccat ggtgctgagg tccgttagct agaggtgccg acagtttttc
    15061 acaaatctgc tcaagtattg gaagaagaga tgaatcgtta tcaacctgac tttgtccttt
    15121 gtattgggca agctggtgga agaactagtt tgacacctga acgagtggcc attaatcaag
    15181 acgatgcacg catttctgat aacgaagata atcaaccgat tgaccgtccc attcgcccag
    15241 atggtgcttc ggcctacttt agtagtttgc cgattaaagc gatggttcaa gctataaaaa
    15301 agagggctta ccggcctctg tttccaatac ggcagggact tttgtctgca gccatttgat
    15361 gtatcaggct ctctatttgg tagaaaagaa atttccatat gttaaggcag gttttatgca
    15421 tattccttat atgatggaac aggtggtgaa cagacagact attccagcta tgagtttagt
    15481 ggatattcgg cgagggatag aagcagcaat cggcgctatg atagaacatg gagatcagga
    15541 actcaagttg gtaggcggag aaactcattg atagaaaaaa gcttgagtgg aaaaaccttc
    15601 aagcttttgg acgttttcga gccaatactg ctcggtaaaa cataatttta gtgcattgga
    15661 tataaggtag gagtgaaaaa ctagcaatgc caaaggtaat ccaattgagg aagtaccaag
    15721 gaagaagctg taaatctagg acaaagcgct ggaacttgta gcccttcata aaggaacggc
    15781 tagtttttag gattcgtctt ggtgggacct gtcctaggtc tagactataa cagagaagaa
    15841 attccacctg tgaataggca taatactgtg gaatatagag gatatttcct acaatgatca
    15901 agatgagact tgcaagaaag tagagtccaa agaccatgag gaaacgctcg gtttcaactg
    15961 atgagagatc tagatttgga aactcaggat gtagggtgac gaattttttg gctaaaaagc
    16021 tactataaaa gaggaggtaa atcccaagta aattagggat actccataaa aagagataga
    16081 aacgtttgag aagtagggtc aaaaaggttt gagaaaagcg ctcctcatca aagagagcta
    16141 ggctgttttt tacagatggc tccgttttag aatctttcat gagtgtcagt gttgcataga
    16201 cggaactggt caaaagaata gtcccgataa aggagactag tagaggaaag aggtaggttt
    16261 gaagtatttg gccaagtatg ctgaaaaatg gctgttctaa aacagtcccg tggatccgag
    16321 ataagggatt aagaaaacta gataagatga ccagcatact gggaaggata tagaggagaa
    16381 agagacgggg ggtgtcagcc tgaaaatgtt ttgactcctg acgaattgtt tttaaatcaa
    16441 tttttggata gttcattctc ttattatacc atagttctta tacatagttc gtgacagttc
    16501 ctactttttt tgataaaatc atacagtgtg tccttgggca cactgtatga actgggactg
    16561 tctttcccag cttcggaggt aaaaaatgtc agattcacca atcaaatatc gtttgattaa
    16621 gaaagaaaaa cacacaggag ctcgtctggg agaaatcatc actccccacg gtacctttcc
    16681 gacacctatg tttatgccag ttgggacaca agccactgtc aaaactcagt cacctgaaga
    16741 attgaaggag atgggttcgg gaattatcct atcaaacacc tatcatctct ggcttcgccc
    16801 tggagatgaa ctcattgcac gcgctggtgg tctccacaag ttcatgaatt gggaccagcc
    16861 tatcttgaca gatagtggtg gttttcaggt ttattcttta gcagatagcc gtaatatcac
    16921 agaagaagga gtaaccttta aaaatcatct aaatggttct aagatgttcc tatccccaga
    16981 aaaagccatc tctattcaga ataatctggg ttcagacatc atgatgtcct ttgatgaatg
    17041 tcctcagttt tatcaacctt atgactacgt taagaaatcg atcgagcgta ccagccgttg
    17101 ggctgagcgt ggtttgaagg ctcaccgtcg tccacatgac caaggtttgt ttggaattgt
    17161 gcaaggtgca ggatttgaag accttcgccg ccaatcagct catgatcttg tcagcatgga
    17221 tttctcaggc tactctatcg gtggtttggc agtgggagaa acccatgaag agatgaatgc
    17281 ggtcttggac tttacaactc aactgctgcc tgaaaataaa cctcgttatc tgatgggtgt
    17341 gggagcgcca gatagcttga tcgatggggt cattcgtggg gtggatatgt ttgactgtgt
    17401 cttaccgact cgaattgctc gtaacgggac ttgtatgacc agtcaaggac gtttggttgt
    17461 gaaaaatgcc cagtttgctg aggactttac gccactggat cctgagtgtg actgctacac
    17521 atgtaataac tatacacgcg cttaccttcg tcacctgctc aaggctgatg aaacctttgg
    17581 tatccgcttg actagctacc acaatcttta cttcttgctt aacctgatga agcaagtgcg
    17641 acaagccatc atggatgaca atctcttgga attccgtgag tattttgtgg aaaaatatgg
    17701 ctataataag tcaggacgta atttctaaaa tggaattgat ataaaaaaat cctaagtttt
    17761 ctcttaggat ttttcttctt tttttgatag aataaagtgt acaatgaaag gaagaataaa
    17821 ctcgtatgcg cattaaatgg ttttccttgg ttaggattac aggtttactt ttggtactct
    17881 tgtatcactt ctttcagacg atctttcctg gaggattttt cggggtagat gtctttttca
    17941 cattttcagg tttcctgatt acagctctac tcattgaaga attttctaaa aaccatgaga
    18001 ttgatttgat aggatttttt agaagacgct tttatcggat tgtgccacct gtggttttga
    18061 tggtcttggt gaccatgcct tttactttct tggttcgcca agactatgtt gctggaattg
    18121 gtggccagat tgcgagcgtc ttaggcttta tgaccaactt ctatgaactc ctaacaggtg
    18181 ggagttatga atctcagttc attcctcatt tgtttgttca taattggagt ttggcagttg
    18241 aggttcacta ctatattctt tggggattgg cagtttggtt cttatccaaa caagctaaat
    18301 caaatggtca gttgaagggg atagtctttc tcttatctgc tgttgccttc ttgatcagtt
    18361 tcttctccat gtttattggt agttttctag tgacctctta ttcctctgtt tatttctcca
    18421 gtttaactca tgtctatcca ttctttttgg gaagtatgtt agcaactatt gtaggtgttc
    18481 gtcagacgac ttccctcgtc aagcagttgg ataaaatctg ggatttacga aagactttgg
    18541 tagtttttgg aggaggcttt ggtttcctag ttcttttgac tttctttgtc aaattcactt
    18601 atctttttgc ctatcttatc ggcttcttgc ttgccagtct tgcagctctt gccatgattc
    18661 tggcggcgcg tgtcttacat gaaaagacac atcatataca ggagccgaag attatcagct
    18721 ttttagcgga tactagctat gcggtttatc ttttccattg gcctttctat atcattttct
    18781 cacagttgac atcaaatctt cttgctgtat tactgactct gatttgttct tatggctttg
    18841 ccagtctgtc attctatgta ttggaacctt ggattgcagg caagaacaca cctattttac
    18901 aaactcttcg tcccctgcct tatattcacg caattcttgt agcaggtaca ggaatcttga
    18961 ccatcattgt ctgcacggtg accttgttgg caccacaagt gggagcgttt gagacagact
    19021 tgactgtcaa tggcttgaag caagctgcaa caaatattgg ccagaccaag gtgatggcag
    19081 aacgggcaga tgcaaacagt ttgggaattg ctgatggcac tatgttaatt ggtgactcag
    19141 tggctttaag ggcaaataca gcactacaga cagctcttcc tggagcacag attaacgcgc
    19201 aggtcagcgt aacaaccaag accgcaaatg aaatcatgct aaataatagc cagaataaat
    19261 ttttacctaa gacggtggtc attgcgactg gggtaaataa tcctgagaat tacaaggatg
    19321 actgggacag tatcgtgaaa aatcttccta agggacacca tatgattttg gtgactcctt
    19381 atgagggaga taagacaaaa gagacctatg ccatcgttga gaaggctgct gcctatatga
    19441 gagaattggc agagaagaca ccttacatta cgatagcaga ttggaatcaa gttgcgaaag
    19501 agcatccaga aatttgggca ggaacagacc aggttcattt cgggagtgag agtagcacta
    19561 tcgaagcagg agcaaaattg tatgcagata cgattgccac agctttgcag acagctcaag
    19621 acaagccggt taaatcaaaa taacttgtat taaaaaagag aagagttgga gaaatccagc
    19681 tcttttaaaa tatctccaaa aaataggtct ataccattta caaataaaaa agaaaggttt
    19741 ataatgtaat tgacataata aattgcagaa tcaatctttt aaggaggtta acattatgcc
    19801 taactatatt aaagcggatc agtttttcta cccacacgga gttcgtcgag gtggttactt
    19861 ggaacttgtg gacggcaagt ttgggaaaca tgtagagcag attcctgaag gggctgaggt
    19921 gattgactat acaggttata gcattgcccc aggtcttgtg gatactcata ttcatggata
    19981 tgcaggtgta gatgtgatgg acaacaacat tgaaggtaca ttgcatacta tgagtgaagg
    20041 acttcttagt accggtgtta ccagtttctt acccacaact ttaacagcca cttatgagca
    20101 attgcttgca gtcactgaaa atcttggaaa ccattataaa gaagcaacag gtgctaagat
    20161 tcgtgggatt tattatgaag gtccatattt cacagaaact tttaaggggg cacaaaatcc
    20221 aacttatatg agagacccgg gtgttgagga gtttcattct tggcaaaaag cggcaaatgg
    20281 cttgcttaat aaaattgccc ttgcaccaga acgtgatggg gtggaagact ttgttcgtac
    20341 agttacgggc gaaggtgtga cggttgctct tggacattca aacgcgactt ttgatgaagc
    20401 caaaaaagca gtcgatgctg gagcgagtgt ttgggtgcat gcctacaatg gaatgcgtgg
    20461 gttgactcac cgtgaattgg gtatggttgg agccatgtac caattgccac atacctatgc
    20521 agagttgatc tgtgatggtc accacgtaga tccaaaggct tgcgaaattc ttatcaaaca
    20581 aaaaggaaca gaaaacatcg ctcttatcac agactgtatg acagctgggg gattggaaga
    20641 cggagattat atgttgggag aattcccagt tgtcgttgca aatggaactg cacgcctcaa
    20701 atcgacaggt aacttggcag gttctatcct caaactcaaa gatggtttga agaatgtggt
    20761 cgaatgggga attgcgaatc cgcatgaagc agtcatgatg gccagcttca acccagctaa
    20821 atccgttcac atcgatgacg tctgtggcca aatccgtgaa ggctacgacg ctgacttcat
    20881 cgtattagat aaagatttgg aattggtagc aacctaccta gatggcgtaa aacgttatca
    20941 agcataagag agaaagcaga agttagagac taacttctgc ttttttatgc agggtacttt
    21001 actggtaaat aaaaagttaa aaaaatcaca aaaaaagctt gaagaaacaa agaaaaaggc
    21061 ttacaattga actataaata ttacaaataa aaaaacggag gagtgcttta tgaaagccta
    21121 tacttatgtt aaaccaggac ttgcttcttt tgttgatgta gacaaaccag ttattcgcaa
    21181 gccaacagac gctattgtgc gtattgtaaa aaccactatt tgtggaacag acctccatat
    21241 tatcaaaggg gatgttccta cttgccaaag tggtaccatt cttggccacg aagggattgg
    21301 gattgttgaa gaagttgggg aaggagtttc caacttcaaa aaaggtgaca aggtcttgat
    21361 ttcttgcgtc tgtgcctgtg gtaaatgcta ctactgtaaa aaaggaattt atgctcactg
    21421 tgaagacgaa gggggctgga ttttcggtca cttgattgat ggtatgcagg ctgaatatct
    21481 acgtgtccct catgcagata atactcttta ccatactcca gaagacttgt cagatgaagc
    21541 tttggttatg ctgtcagaca ttctgcctac tggatatgaa attggtgtct taaaagggaa
    21601 agtagaacct ggttgcagcg tagccattat tggttcaggt ccagttggat tggctgctct
    21661 tttaacagcc caattctatt caccagctaa attgattatg gtagacctag acgataaccg
    21721 cttggaaact gccctatcat tcggtgcgac tcataaggtt aattcttcag accctgaaaa
    21781 agccattaaa gaaatttatg atttgacaga tggtcgtggt gtggatgtcg ctatcgaagc
    21841 tgttggtatt cctgcaacat ttgatttctg tcaaaagatt atcggtgtag acggaacggt
    21901 tgccaactgt ggtgtgcatg gtaaaccagt tgaattcgat ttagataaac tttggattcg
    21961 caacatcaat gtaacaactg gtttggtatc tacaaatacg actccacaat tgttgaaagc
    22021 gcttgaaagt cataagattg aaccagaaaa attggtaact cactatttca aactcagtga
    22081 aattgaaaaa gcctacgaag tcttcagtaa ggcagcagac caccatgcca ttaaggtcat
    22141 tatcgaaaac gatatctcag aagcctaagt agtaaaaata tttggctctt tgtcaactgt
    22201 agtgggttga agtcagctaa gctcgagaaa ggacaaaatt cgtcctttct ttttgatgtt
    22261 cagagcgata aaaatccttt ttttgaagtt ttcaaagttc cgaaatccaa aggcgtttcg
    22321 tttgataagt ttgatgagat tattggtcgc ttctaatttt gcgttggaat aaggtaat
//
LOCUS       DAVLXH010000033        21893 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00028199
            SAMN33607166-rid17955573.denovo.033, whole genome shotgun sequence.
ACCESSION   DAVLXH010000033 DAVLXH010000000
VERSION     DAVLXH010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607166
            Sequence Read Archive: SRR23725544
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21893)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21893)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721421.1
            Genome Coverage       :: 115x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:42:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,210
            CDSs (total)                      :: 2,161
            Genes (coding)                    :: 2,023
            CDSs (with protein)               :: 2,023
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 73 of 138
            Pseudo Genes (incomplete)         :: 60 of 138
            Pseudo Genes (internal stop)      :: 40 of 138
            Pseudo Genes (multiple problems)  :: 31 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21893
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607166-rid17955573.denovo.033"
                     /strain="AUSMDU00028199"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1349"
     gene            complement(<1..166)
                     /gene="blpI"
                     /locus_tag="VYO11_001388"
     CDS             complement(<1..166)
                     /gene="blpI"
                     /locus_tag="VYO11_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpI"
                     /protein_id="HEV1595938.1"
                     /translation="MNTKMMEQFSVMDNEELEIVSGGRGNLGSAIGGCIGAVLLAAAT
                     GPITGGAATLI"
     gene            448..1035
                     /locus_tag="VYO11_001389"
     CDS             448..1035
                     /locus_tag="VYO11_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase C39"
                     /protein_id="HEV1595939.1"
                     /translation="MTSYKRTFVPQIDARDCGVAALASIAKFYGSDFSLAHLRELAKT
                     NKEGTTALGIVKAADEMGFETRPVQADKTLFDMSDVPYPFIVHVNKEGKLQHYYVVYQ
                     TKKDYLIIGDPDPSVKITKMSKERFFYEWTGVAIFLATKPSYQPHKDKKNGLLSKLPS
                     SDFQTKISHCLHCSLKLIGHYYQYRWFLLSPRNLR"
     gene            962..2605
                     /locus_tag="VYO11_001390"
     CDS             962..2605
                     /locus_tag="VYO11_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
                     /protein_id="HEV1595940.1"
                     /translation="MVLSSLLVTIINIGGSYYLQGILDEYIPNQMKSTLGIISVGLVI
                     TYILQQVMSFSRDYLLTVLSQRLSIDVILSYIRHIFELPMSFFATRRTGEIISRFTDA
                     NSIIDALASTILSLFLDVSILILVGGVLLAQNPNLFLLSLLSIPIYMFIIFSFMKPFE
                     KMNHDVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQNIDSEFVDYLEKSFKLSKYS
                     ILQTSLKQGTKLVLNILILWFGAQLVMSSKISIGQLITFNTLFSYFTTPMENIINLQT
                     KLQSAKVANNRLNEVYLVESEFQVQENPVHSHFLMGDIEFDDLSYKYGFGRDTLTDIN
                     LTIKQGDKVSLVGVSGSGKTTLAKMIVNFFEPYKGHISINHQDIKNIDKKVLRRHINY
                     LPQQAYIFNGSILENLTLGGNHMISQEDILKACEVAEIRQDIERMPMGYQTQLSDGAG
                     LSGGQKQRIALARALLTKSPVLILDEATSGLDVLTEKKVIDNLMSLTDKTILFVAHRL
                     SIAERTNRVIVLDQGKIIEVGSHQELMQAQGFYHHLFNK"
     gene            2616..3977
                     /locus_tag="VYO11_001391"
     CDS             2616..3977
                     /locus_tag="VYO11_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin secretion accessory protein"
                     /protein_id="HEV1595941.1"
                     /translation="MNPNLFRSVEFYQRRYHNYATVLIIPLSLLFTFILIFSLVATKE
                     ITVTSQGEIAPTSVISSIQSTSDNPILANHLVANQVVEKGDLLIKYSETMEESQKTAL
                     ATQLQRLEKQKEGLGILKQSLEKATDLFSGEDEFGYHNTFMNFTKQSHDIELGITKTN
                     TEVSNQANLANSSSSAIEQEITKVQQQIGEYQELRDAIINNRARLPTSNPHQSILNRY
                     LVASQGQTQGTAEEPFLSQINQSIAGLESSIASLKIQQAGIGSVATYDNSLATKIEVL
                     RTQFLQTASQQQLTVENQLTELKVQLDQATQRLENNTLTAPSKGIVHLNSEFEGENRI
                     PTGTEIAQVFPIITDTREVLITYYVASDYLPLLDKGQTVRLKLEKIGNHGITIIGQLQ
                     TIDQTPTRTEQGNLFKLTALAKLSNEDSKLIQYGLQGRVTSVTAKKTYFDYFKDKILT
                     HSD"
     gene            4034..4189
                     /gene="blpC"
                     /locus_tag="VYO11_001392"
     CDS             4034..4189
                     /gene="blpC"
                     /locus_tag="VYO11_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system pheromone BlpC"
                     /protein_id="HEV1595942.1"
                     /translation="MDKKQNLTSFQELTTTELNQITGGGWWEELLHETILSKFKITKA
                     LELPIQL"
     gene            complement(4231..5571)
                     /locus_tag="VYO11_001393"
     CDS             complement(4231..5571)
                     /locus_tag="VYO11_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV1595943.1"
                     /translation="MNIAWILLYALVINGLEIVIFFKVDGIGLTFDRIFKAFLLKFLL
                     GIIFTTFQFLAVSKYLSYFIEPLFGIGLSFLLLRGLPKKILIFYGLFPMILVELFYRG
                     VSYFVLPFLGQGIVDGDGNPIFLLIMIFVCFIVLVFLKWLDYDFTRLRREFLDTGFQK
                     SLTKINWAMGAYYLVMQSLSYLEYEQGIQSTTVRHLILVFYLLFFMGGIKKLDTYLKE
                     KLQEELNQEQTLRYRDMERYSRHIEELYKEIRSFRHDYTNLLTSLRLGIEEEDMEQIK
                     EIYDSVLRDSSQKLQDNKYDLGRLVNIRDRALKSLLAGKFIKAREKNIVFNVEVPEEI
                     QVEGMSLLDFLTIVSILCDNAIEASAEASQPHVSIAFLKNGAQETFIIENSIKEEGID
                     ISEIFSFGASSKGEERGVGLYTVMKIVESHPNTNLNTTCQNQVFRQVLTVIHAE"
     gene            complement(5585..6322)
                     /locus_tag="VYO11_001394"
     CDS             complement(5585..6322)
                     /locus_tag="VYO11_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001219153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1595944.1"
                     /translation="MRIFVLEDDFSQQTRIETTIEKLLKEHHITPSSFEVFGKPDQLL
                     AEVHEKGAHQLFFLDIEIRNEEMKGLEVARKIREQDPYALIVFVTTHSEFMPLSFRYQ
                     VSALDYIDKALSAEEFESRIETALLYANSQDSKSLAEDCFYFKSKFAQFQYPFKEVYY
                     LETSPRPHRVILYTKTDRLEFTASLEEVFKQEPRLLQCHRSFLINPANVVHLDKKEKL
                     LFFPNGGSCLIARYKVREVSEAINNLH"
     gene            complement(6327..6665)
                     /locus_tag="VYO11_001395"
     CDS             complement(6327..6665)
                     /locus_tag="VYO11_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1595945.1"
                     /translation="MKHMIIQTQKTVYKVNIDDIYYIQTHPTKAHTVQIVTEKASFNM
                     LQNLSNLENQCGETLMRCHRNCLVNLDKLKSIDFQERILFLGEEGQYAVKYARRRYRE
                     IRQKWLKQGE"
     gene            6941..7270
                     /locus_tag="VYO11_001396"
     CDS             6941..7270
                     /locus_tag="VYO11_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
                     /protein_id="HEV1595946.1"
                     /translation="MTDTDPIKRAHTLITDLNKAYQACKQASADDVRFQEQLNSILGF
                     LAKAETVDNRFLIELEKFYQTSSLLMGLSALDPDAPTRAAWRAYDRFHFDQVKTKLIL
                     NENQRAN"
     gene            complement(7438..8487)
                     /locus_tag="VYO11_001397"
     CDS             complement(7438..8487)
                     /locus_tag="VYO11_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1595947.1"
                     /translation="MKDLFLKRKQAFRKECLGYLRYVLNDHFVLFLLVLLGFLAYQYS
                     QLLQHFPENHWPILLFVGITSVLLLLWGGIATYMEAPDKLFLLVGEEAIKLHLKRQTG
                     ISLVFWLFVQTLFLLLFAPLFLAMGYGLPVFLLYVLLLGVGKYFHFRQKASKFFTETG
                     LDWDYLISQESKRKQVLLRFFALFTQVKGISNSVKRRAYLDFILKAVQKVPGKIWQNL
                     YLRSYLRNGDLFALSLRLLLLSVLAQVFIEQAWIATAVVVLFNYLLLFQLLALYHAFD
                     YQYLTQLFPLDKGQKEKGLQEVVRGLTSFVLLVELVVGLITFQEKLALLALLGAGLVL
                     LVLYLPYQVKRQMQD"
     gene            complement(8484..9215)
                     /locus_tag="VYO11_001398"
     CDS             complement(8484..9215)
                     /locus_tag="VYO11_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1595948.1"
                     /translation="MLEIKNLTGGYVHVPVLKDVSFTVESGQLVGLIGLNGAGKSTTI
                     NEIIGLLAPYSGSININGLTLQGDATSYRKQIGYIPETPSLYEELTLREHIETVAMAY
                     GIEQKVAFERVEPLLKMFRLEQKLDWFPVHFSKGMKQKVMIICAFVVDPSLFIVDEPF
                     LGLDPLAISDLIQLLEVEKQKGKSILMSTHVLDSAEKMCDAFVILHKGEVRAKGNLLQ
                     LREAFDMPEASLNDIYLALTKEEDL"
     gene            9283..9693
                     /locus_tag="VYO11_001399"
     CDS             9283..9693
                     /locus_tag="VYO11_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HEV1595949.1"
                     /translation="MSDCIFCKIIAGEIPASKVYEDEQVLAFLDISQVTLGHTLVVPK
                     EHYRNLLEMDATSASQLFAQVPKVAQKVMKVTKAAGMNIISNCEEVAGQTVFHTHVHL
                     VPRYSADDDLKIDFIAHEPDFDKLAQVAETIKNA"
     gene            9703..9990
                     /locus_tag="VYO11_001400"
     CDS             9703..9990
                     /locus_tag="VYO11_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1595950.1"
                     /translation="MKLSNLLLFAGAAAGSYLVTKNRQTITDEVLNTTDRVQAIKDDV
                     DIIQNSLQIINQQKELIKEYQEDLTYKFKVLEKDIQTRLAVIKEMQGTEDK"
     gene            complement(10312..11448)
                     /gene="dnaJ"
                     /locus_tag="VYO11_001401"
     CDS             complement(10312..11448)
                     /gene="dnaJ"
                     /locus_tag="VYO11_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001066288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HEV1595951.1"
                     /translation="MNNTEFYDRLGVSKNASADEIKKAYRKLSKKYHPDINKEPGAED
                     KYKEVQEAYETLSDDQKRAAYDQYGAAGANGGFGGAGGFGGFNGAGGFGGFEDIFSSF
                     FGGGGSSRNPNAPRQGDDLQYRVNLTFEEAIFGTEKEVKYHREAGCRTCNGSGAKPGT
                     SPVTCGRCHGAGVINVDTQTPLGMMRRQVTCDVCHGRGKEIKYPCTTCHGTGHEKQAH
                     SVHVKIPAGVETGQQIRLAGQGEAGFNGGPYGDLYVVVSVEASDKFEREGTTIFYNLN
                     LNFVQAALGDTVDIPTVHGDVELVIPEGTQTGKKFRLRSKGAPSLRGGAVGDQYVTVN
                     VVTPTGLNDRQKVALKEFAAAGDLKVNPKKKGFFDHIKDAFDGE"
     gene            complement(11850..12206)
                     /locus_tag="VYO11_001402"
     CDS             complement(11850..12206)
                     /locus_tag="VYO11_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000114361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanine-N7)-methyltransferase"
                     /protein_id="HEV1595952.1"
                     /translation="MSVLDDEYLKNTRKVYNDFCNQADNYEAAKGFIDNIPVECLTIY
                     REIILAEHDSCVKNDEAVRNFVTSVLLSAFVSAMVSAMISLEIQTYKFVIPFIIGMIW
                     TVVVFLMINWNYIGKY"
     gene            complement(12208..14031)
                     /gene="dnaK"
                     /locus_tag="VYO11_001403"
     CDS             complement(12208..14031)
                     /gene="dnaK"
                     /locus_tag="VYO11_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HEV1595953.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGTESKIIANPEGNRTTPSVVSFKN
                     GEIIVGDAAKRQAVTNPDTVISIKSKMGTSEKVSANGKEYTPQEISAMILQYLKGYAE
                     DYLGEKVTKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTDK
                     EEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNKLGGDDFDQKIIDHLVAEFKKEN
                     GIDLSTDKMAMQRLKDAAEKAKKDLSGVTSTQISLPFITAGEAGPLHLEMTLTRAKFD
                     DLTRDLVERTKVPVRQALSDAGLSLSEIDEVILVGGSTRIPAVVEAVKAETGKEPNKS
                     VNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTSK
                     SQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDIDK
                     NGIVSVKAKDLGTQKEQTIVIQSNSGLTDEEIDRMMKDAEANAEADKKRKEEVDLRNE
                     VDQAIFATEKTIKETEGKGFDAERDAAQAALDDLKKAQEDNNLDDMKAKLEALNEKAQ
                     GLAVKLYEQAAAAQQAQEGAEGAQATGNAGDDVVDGEFTEK"
     gene            complement(14511..15035)
                     /gene="grpE"
                     /locus_tag="VYO11_001404"
     CDS             complement(14511..15035)
                     /gene="grpE"
                     /locus_tag="VYO11_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000046028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HEV1595954.1"
                     /translation="MAQDIKNEEVEEVQEEEVVETAEETTPEKSKLDLANERADEFEN
                     KYLRAHAEMQNIQRRANEERQNLQRYRSQDLAKAILPSLDNLERALAVEGLTDDVKKG
                     LGMVQESLIHALKEEGIEEIAADGEFDHNYHMAIQTLPADDEHPVDTIAQVFQKGYKL
                     HDRILRPAMVVVYN"
     gene            complement(15062..16096)
                     /gene="hrcA"
                     /locus_tag="VYO11_001405"
     CDS             complement(15062..16096)
                     /gene="hrcA"
                     /locus_tag="VYO11_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HEV1595955.1"
                     /translation="MVTERQQDILNLIIDIFTKTHEPVGSKALQESINSSSATIRNDM
                     AALEKQGLLEKAHTSSGRMPSVAGFQYYVKHSLDFDRLAENEVYEIVKSFDQEFFKLE
                     DILQEAANLLTDLSGCTVVALDVEPSRQRLTAFDIVVLGQHTALAVFTLDESRTVTSQ
                     FLIPRNFLQEDLLKLKSIIQERFLGHTVLDIHYKIRTEIPQIIQRYFTTTDNVIDLFE
                     HIFKEMFNENIVVAGKVNLLNFANLAAYQFFDQPQKVALEIREGLREDQMQNVRVADG
                     QESCLADLAVISSKFLIPYRGVGILAIIGPVNLDYQQLINQVNVVNRVLTMKLTDFYR
                     YLSSNHYEVH"
     gene            complement(16257..16769)
                     /locus_tag="VYO11_001406"
                     /pseudo
     CDS             complement(16257..16769)
                     /locus_tag="VYO11_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001088710.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2812 domain-containing protein"
     gene            17377..19710
                     /locus_tag="VYO11_001407"
     CDS             17377..19710
                     /locus_tag="VYO11_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEV1595956.1"
                     /translation="MVEFIKSKKEMSEEDIKANFITPAIVSKGWKNGEHIAYEEYFTD
                     GRIEVRGDKARRKEGKKSDYSLYYQFGTRIAIVEAKDNKHSVRAGLQQAIEYGEILDV
                     PFVYSSNGDGFIEHDRITREERELELDEFPTREELFSRMTKEKGLTYEITEAISTPYY
                     TDAFSMKTPRYYQQIAINRTIETVARGQKRVMFVMATGTGKTFMAFQIIHRLRKAGLA
                     KRVLFLADRNILVDQTMAEDFRPFEKVMTKITPKLLTAPEKLNSFEIYLGLYQQLTGE
                     DGTETHYQKFDKDFFDLIVIDEAHRGSAKENSNWRKIIDYFSSATQIGMTATPKETKN
                     ASNTEYFGEPIYTYSLKQGIEDGFLAPYRVMRVNLDVDVDGYRPETGKVDTNGQLIED
                     RYYGRKDFDKTIVIDDRTQRVAKFVSDYMKQNNARFDKTIVFCVDIDHAERMRAALVK
                     ENLDLVQEDYRYVMQVTGDNAEGKAQLDNFMDVNSNFPAMVTTSKLLTTGVNAKTCRL
                     IVLDSNIQSMTEFKQIIGRGTRLYPQKGKEFFTIIDFRNVTNLFADPDFDGEPVKVLE
                     TGAKTVSGSTPGFVDEEGDPVEKYIVTDKQVTILNSTVQVLDENGKLITESLTDYTRK
                     NILGSYATLNDFITVWHTADKKKLILDELYKKGVYLDAIRESEGISEQEIDDFDLLLK
                     LAYGQKELTKTERINKLKQSGYLYKYSEEARAVLEILLNKYMDKGIGELESIETLKLP
                     EFQIYGGTFKIINTYFGDKKRYLQAIKELEQELFTVA"
     gene            19723..21186
                     /locus_tag="VYO11_001408"
     CDS             19723..21186
                     /locus_tag="VYO11_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HEV1595957.1"
                     /translation="MSITSFVKRIQDITRNDAGVNGDAQRIEQMSWLLFLKIYDSREM
                     VWELEEDEYESIIPEELKWRNWAHAQNGERVLTGDELLDFVNNKLFKELKELEITSNM
                     PIRKTIVKSAFEDANNYMKNGVLLRQVINVIDEVDFNSPEDRHSFNDIYEKILKDIQN
                     AGNSGEFYTPRAATDFIAEVLDPKLGESMADLACGTGGFLTSTLNRLSSQRKTSEDTK
                     KYNTAVFGIEKKAFPHLLAVTNLFLHEIDDPKIVHGNTLEKNVREYTDDEKFDIIMMN
                     PPFGGSELETIKNNFPAELRSSETADLFMAVIMYRLKENGRVGVILPDGFLFGEGVKT
                     RLKQKLVDEFNLHTIIRLPHSVFAPYTGIHTNILFFDKTKKTEETWFYRLDMPDGYKN
                     FSKTKPMKSEHFNPVRDWWENREEILEGKFYKSKSFTPSELAELNYNLDQCGFPKEEE
                     EILNPFELIQNYQAERATLNHKIDNVLADILQLLEDK"
     gene            21186..>21893
                     /locus_tag="VYO11_001409"
     CDS             21186..>21893
                     /locus_tag="VYO11_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000187262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEV1595958.1"
                     /translation="MTPEQLKASILQRAMEGKLVPQNPNDEPASELLKRIKAEKEKLI
                     SEGKIKRDKKETEIFRGDDGKHYGKFADGSTQEIDVPYDIPDTWEWVRIKSIYWNFGQ
                     NKPEKSFRYIDTSSIDRKKNIINYKNLQYLSPEQAPSRARKLVSQNSVLFSTVRPYLK
                     NIAVVRELKEYLIASTAFIVLDTLLNETYLKYYLLSDNFINRVNNKSTGTSYPAINDY
                     NFNLLLIALPPLSEQQRI"
BASE COUNT         6956 a         4431 c         4023 g         6483 t
ORIGIN      
        1 aaataagtgt tgctgctccc ccagttatcg gaccagtcgc agcagctaat agtactgctc
       61 caatacaacc accgattgca gatcctaaat tgcctcttcc tccactaact atttcgagtt
      121 cttcattatc cataacagaa aattgttcca tcatttttgt attcatgaca aatactcctt
      181 ttttcttttt ttatttttgt cttgttgtaa ctttgataag tttagtatat catcgttttt
      241 taaaattttt catccagatc ttgaattgtc atcgaaacgt cttgaattag cttttttatt
      301 tcaagccacc tctaaatgtt taaaaaaaat aatttctaat cactttttta ccattcagga
      361 agttttaatg actattcaag atttcataaa atatgaactt agttttatga cataatagac
      421 ctatccacta tatgaaagga attgccaatg acttcttata aacgtacatt tgttcctcaa
      481 atagatgcga gagactgtgg tgtcgctgcc ttagcctcga ttgctaaatt ctatggttca
      541 gatttttctc tagctcactt gagagaactt gcaaagacca ataaagaagg gacgactgct
      601 cttggcattg taaaagccgc tgatgaaatg ggctttgaaa caagacctgt tcaagcagat
      661 aaaacgctct ttgacatgag tgatgtcccc tatccattta tcgttcacgt taacaaagaa
      721 ggaaaactcc aacattacta tgttgtctat caaacaaaga aagactatct gattattggt
      781 gatcctgacc cttctgtaaa aatcactaaa atgtcaaaag aacgcttttt ctatgaatgg
      841 actggagtag ctatttttct agctaccaaa cccagctatc aaccccataa agataaaaag
      901 aatggtctac taagcaagct tccttcctct gattttcaaa caaaaatctc tcattgctta
      961 cattgttctc tcaagcttat tggtcactat tatcaatata ggtggttctt actatctcca
     1021 aggaatctta gatgaataca tcccaaatca gatgaaatca actttaggaa tcatctcagt
     1081 tggtctggtt atcacctata tcctccaaca agtcatgagc ttctccagag attatctcct
     1141 aaccgttctg agccagagat taagcattga tgtgatttta tcctatattc gccatatttt
     1201 tgaacttccc atgtctttct ttgcgacacg tcgtacagga gaaatcattt cacggttcac
     1261 agatgctaac tctattatag atgccttggc ttctaccatt ctttctcttt ttctggatgt
     1321 ttctattctg attcttgtag ggggagtctt gctggcacaa aaccctaatc tcttcctcct
     1381 ttctcttctt tccattccta tatacatgtt catcatcttt tcttttatga aacctttcga
     1441 aaaaatgaac catgatgtca tgcaaagtaa ttctatggtt agctctgcca ttatcgaaga
     1501 tatcaacggg attgaaacta taaagtcgct cacgagtgaa gaaaatcgct atcaaaatat
     1561 agacagcgaa tttgtagatt atttggaaaa atcctttaag ctcagtaaat attctatttt
     1621 acaaacgagt ttaaagcagg gaacaaaatt agttctgaat atccttatcc tatggtttgg
     1681 cgctcaatta gtcatgtcaa gtaaaatttc tatcggtcag ctgattacct ttaacacact
     1741 tttttcttac tttacaactc ctatggaaaa tattatcaac ctccaaacca aactccaatc
     1801 tgcgaaggtc gctaataacc gtttgaacga agtctatcta gtcgaatctg aatttcaagt
     1861 tcaagaaaac cctgttcatt cacatttttt gatgggcgat attgaatttg atgacctttc
     1921 ttataagtat ggttttggac gagatacctt aacagatatt aatctcacga ttaaacaagg
     1981 agataaggtt agcctagttg gagttagtgg ttctggtaaa acaactttag ccaaaatgat
     2041 tgtcaatttc tttgaaccct acaaagggca tatttccatc aatcatcagg atattaaaaa
     2101 cattgataaa aaagtcttgc gccgtcatat taattaccta ccccaacaag cctatatctt
     2161 taatggctct attttggaaa acttaacctt gggcggtaat catatgatta gtcaagaaga
     2221 tattctaaaa gcttgtgaag tagctgaaat ccgtcaagac attgaaagaa tgcctatggg
     2281 ctatcaaact cagctctctg atggagctgg tctatcagga ggacagaagc aacgaatcgc
     2341 tctcgctcgt gctcttttaa ctaaatctcc tgttttaata ctagatgaag ctactagcgg
     2401 tcttgatgtc ttgactgaga aaaaagttat agataatctt atgtccctaa ctgataaaac
     2461 cattctcttt gtagcccatc gtctcagtat agccgaacga accaaccgtg tcattgttct
     2521 tgaccagggg aaaatcattg aagttggtag ccaccaagag ttaatgcagg cgcaaggttt
     2581 ctaccatcat ctattcaata aataaggaga atgtcatgaa tcctaatctt tttagaagcg
     2641 tcgagtttta tcagagacgt taccataact atgcgacagt gttaattata cctctttcat
     2701 tactatttac tttcatcttg attttctccc ttgttgccac aaaagaaatt actgtcactt
     2761 cccaaggaga aatcgcccct acaagtgtca tttcatctat tcagtcaacc agtgataatc
     2821 ctatccttgc taatcattta gtggcaaatc aagtagttga aaaaggggac ttactcatca
     2881 aatactctga aacaatggaa gaaagtcaga aaactgcctt agcaactcaa ttacaaagac
     2941 ttgagaagca aaaagaagga cttggaattt tgaaacaaag cttagaaaaa gcgactgatc
     3001 ttttttctgg cgaggatgaa tttggctacc ataatacctt tatgaatttt actaaacaat
     3061 cccatgatat tgaactgggt atcacaaaga ctaacactga ggtttcaaat caagctaatc
     3121 ttgccaatag cagttcatca gctattgaac aagaaattac aaaagttcaa caacaaattg
     3181 gagaatatca agagctgaga gatgctatca taaataacag agcacgctta ccaactagca
     3241 atccacacca gtcaattttg aatcgttatc ttgtagcctc acaaggacaa acacaaggaa
     3301 cggcagagga gccattttta tctcaaatta atcaaagtat tgcaggtctt gaatcatcta
     3361 tcgcaagcct caaaattcag caagctggta tcggaagtgt agcaacttat gataatagtt
     3421 tagcaaccaa aattgaagta ctccgcactc agtttttaca aacagcctca cagcaacaac
     3481 taaccgtgga gaaccaatta acagaattaa aagtacaact agatcaagcg acacagcgct
     3541 tagaaaacaa taccttaacc gctccaagta aaggtatcgt tcatctgaac agcgaatttg
     3601 aaggtgaaaa tagaattcca actggtacag aaattgctca agtattccct atcatcacag
     3661 atacaagaga agtactaatc acttactacg tagcttctga ctatctacct ctactagata
     3721 aaggacaaac tgtaagatta aaactggaga agattggaaa tcacggcatt accatcatcg
     3781 gccaacttca gacaattgat caaactccta ccagaacaga gcaaggcaat ctctttaaat
     3841 taaccgctct tgcaaaacta tctaatgagg atagtaaact catccaatat ggcttacaag
     3901 gtcgcgtcac tagtgtaact gcaaagaaaa catattttga ttatttcaaa gataaaattt
     3961 taacccattc tgattaattt tcagataaca ctctataact atttattatc ttatcaaaaa
     4021 ggagaatcat aacatggata agaaacaaaa cctaacttca tttcaagaac taacaactac
     4081 cgaactcaac caaattacag gtggaggatg gtgggaagaa ctcttacatg aaacaatttt
     4141 aagtaaattt aaaatcacaa aagcacttga actacctatt cagctataaa aacaagaccg
     4201 agaaacaaga actctcggtc ttgtttttta tcattctgca tgtatcacag taagtacctg
     4261 acgaaagact tgattttggc aggtagtatt tagattggta ttgggatgac tttccacaat
     4321 tttcataacg gtatagagac caactcctct ctcctcccct ttagaacttg ctccaaagga
     4381 gaagatttca gaaatatcga tgccctcttc tttgatggag ttttcaatga taaaagtctc
     4441 ctgtgctcca ttttttaaaa aggcgattga aacatgaggt tgactggcct ctgcactagc
     4501 ttcaatagca ttgtcacaaa ggatagacac aatggttaga aaatcaagta ggctcatccc
     4561 ctcaacctga atctcctcag gaacttcaac attaaagaca atgttctttt ctctagcttt
     4621 tataaatttt ccagctagga gactcttgag ggcacggtca cgaatattca ccaatctgcc
     4681 caggtcatat ttattgtcct gcaatttctg actggaatcc cttaagaccg agtcgtagat
     4741 ctcttttatc tgctccatat cctcctcttc aatgcccaaa cgtaagctgg ttaagaggtt
     4801 agtgtagtca tggcgaaaac tccgaatttc cttgtaaagt tcctctatat gccgactata
     4861 gcgttccata tctctgtagc gcaaggtctg ctcttggttc agttcctcct gaagtttttc
     4921 cttcaaatag gtatccaatt tcttgatacc ccccataaaa aagagtaggt aaaacactag
     4981 gatgagatgg cgaacagtcg ttgattgaat accttgttca tattcaaggt aagatagact
     5041 ttgcatcact agataataag cccccattgc ccagttaatc ttagtaagag acttttgaaa
     5101 acctgtatct agaaactccc ttctcaatct agtgaaatca tagtctaacc atttcaaaaa
     5161 gactaaaact atgaagcaaa cgaatatcat aatcaataaa aagataggat tgccatcccc
     5221 atctacaatt ccttgcccca aaaatggaag cacaaaatag gaaacacctc tgtaaaagag
     5281 ctctactaat atcattggga agagaccata aaaaataagg atttttttag gaagccctct
     5341 taacaataag aaagatagac ctataccgaa caaaggttct ataaaatagg acaaatattt
     5401 acttacagcc aaaaattgaa aagtcgtaaa aatgatccct agaagaaatt tcagaagaaa
     5461 ggccttaaaa attctatcga aagtgagacc aattccatct actttaaaga aaatgacaat
     5521 ttctagtcca ttaataacaa gtgcatacaa caatatccaa gcaatgttca taaactctcc
     5581 tagctcagtg taagttatta atagcctcag acacttccct gaccttataa cgcgcgatca
     5641 gacaacttcc accattggga aagaaaagga gtttttcttt cttatccaaa tgcaccacat
     5701 ttgcaggatt gatgagaaaa gagcgatggc actgcaagag acggggttcc tgcttgaaaa
     5761 cctcctctaa actcgctgta aattccagcc tgtctgtctt ggtatagaga ataacacgat
     5821 ggggtcttgg ggatgtttcg agatagtaaa cctctttaaa aggatactga aattgggcaa
     5881 attttgattt aaagtaaaag caatcttccg ccagactttt actatcttga ctattggcat
     5941 agaggagagc tgtctcgatt cgagattcaa actcctctgc cgaaagggcc ttatcaatat
     6001 agtccagagc agacacttgg tagcgaaagg acaggggcat aaactccgag tgagtcgtca
     6061 caaagacaat cagggcatag gggtcttgtt cccgaatctt tctagccact tccagcccct
     6121 tcatctcctc atttcgaatc tcaatatcca aaaagaatag ctgatgggcc cccttctcat
     6181 gcacctctgc cagcagttgg tctggcttgc caaatacctc aaaagagctg ggagtgatat
     6241 gatgttcctt caagagtttc tcaatcgtcg tttcaatcct agtctgttgg gaaaaatcat
     6301 cctctaaaac aaatattctc atctttttac tctccttgtt ttaaccattt ttgacgaatt
     6361 tctctatagc gacgtctggc atacttgaca gcgtattgac cttcttctcc gagaaaaagg
     6421 attctttctt gaaaatcaat cgattttaat ttatcaagat taaccaaaca atttcgatga
     6481 catctcatca aggtttcccc acattggttc tcaagattac ttaaattttg aagcatatta
     6541 aaactagctt tttctgtaac aatctgtacg gtatgggctt tagttggatg tgtttggata
     6601 tagtagatat cgtcgatgtt tactttatag actgttttct gtgtctgaat aatcatatgt
     6661 ttcattggat tctcctccta agaaaagaat aacagaaaag gtctagccca agcacaccca
     6721 atcctaaaca gtctttgaaa actcctaaaa ggattatttt ccacaacatc atgatgagct
     6781 tacaactatt ttatcataaa attcactcag cgcaattcaa gacatttcaa tgacaattaa
     6841 agatttgaat aaaaaaaaag aattaaaagt gataaactaa cagtatcaaa acacagttgc
     6901 cagaagtaag actggcaccc agattaaagg aggcattccc atgacagata cagaccccat
     6961 caaaagagct catactttga ttactgactt aaacaaagcc taccaagcat gcaaacaggc
     7021 aagcgctgac gacgtccgct ttcaggagca attaaactct attcttggtt ttctagccaa
     7081 ggctgaaaca gtggataatc gattcttgat tgaattggaa aaattttacc agacttccag
     7141 tcttctcatg ggactcagcg ctcttgatcc agatgctcca actcgcgccg cttggcgggc
     7201 ctatgaccgc ttccactttg accaagtcaa gaccaagtta atactcaatg aaaatcaaag
     7261 agcaaactag gaagctagcc gcaagctgta cttgagtacg gtaaggcgac gctgacgtgg
     7321 tttgaagaga ttttcgaaga gtataagtct ctacggacca accattatcc tgtagtaaca
     7381 aaaaagaagc tgagacaaac tgaactcaac ttctttttta gtgtcgtatc agcaatgtta
     7441 gtcctgcatc tgacgtttta cctgataagg caaatacaag actagtaaaa ccaaaccagc
     7501 tcctagtaag gctagaaggg ctagtttttc ttggaaggta atcaacccaa caactaattc
     7561 cacaagtaaa acaaaactgg tcaatcctcg aactacctcc tgtaagcctt tttccttttg
     7621 ccccttatcc agcggaaaga gttgggtcaa atactggtag tcaaaggcat gatagagggc
     7681 cagcaactgg aagagcaaga ggtagttaaa gagaactacc actgctgtcg caatccaagc
     7741 ttgctcgata aaaacctgcg ccagtacgga aagtaagaga agacgaagac tgagagcaaa
     7801 gaggtcgcca tttcgcagat aagaacgcag atagagattt tgccaaatct tcccaggcac
     7861 cttctgaaca gcctttaaga taaagtccag ataggcacga cgcttgacac tgtttgaaat
     7921 tcccttgacc tgcgtaaaga gggcaaagaa acgaagcaag acttgcttac gcttgctttc
     7981 ttgagaaata agatagtccc agtccagtcc agtttcagtg aaaaatttgc tggccttttg
     8041 acgaaagtgg aaatattttc ctacccccaa taaaagcaca tatagcagaa aaactggcaa
     8101 gccataaccc attgctaaaa ataaaggcgc aaataacagc aagaaaaggg tctgtacaaa
     8161 gagccaaaag actagggaaa tgccagtttg acgcttgaga tggagcttga ttgcctcttc
     8221 tccaactaag agaaagagct tgtctggagc ctccatatag gtggcaattc ctccccaaag
     8281 taaaagtaaa acagacgtaa ttcctacaaa caaaaggata ggccaatgat tttcaggaaa
     8341 atgttgtaag agttgactgt actggtaggc tagaaagccc aacaggacaa gcaggaacaa
     8401 gacaaagtgg tcattgagca catagcgcag ataaccaaga cactccttac gaaaggcctg
     8461 ctttctcttt aaaaacaagt ctttcataga tcctcctctt ttgtcagagc caagtaaata
     8521 tcattcaaac tagcctcagg catatcaaag gcttcacgta gttgcaggag attgcctttg
     8581 gcacgcacct ctcccttgtg aagaatgaca aaggcatcac acatcttctc cgccgaatcc
     8641 agcacgtggg tactcatgag aatagacttg cccttttgct tctccacttc caaaagctga
     8701 atcaaatcag aaatagccag cggatcaaga ccaaggaaag gctcatccac gatgaaaaga
     8761 cttggatcca ccacaaaagc acagataatc atgaccttct gcttcatccc ttttgaaaaa
     8821 tgaacaggga accagtctaa tttctgttcc aaacggaaca tttttaacaa gggctctact
     8881 cgttcgaaag ccactttttg ctcaataccg taagccatag caaccgtttc gatatgctct
     8941 ctgagggtca attcctcata cagactaggc gtctcaggaa tgtagccaat ctgcttgcgg
     9001 tagctagtcg catctccttg cagagtcagg ccattgatat tgatggagcc actataaggt
     9061 gccaacagac cgataatctc attgatcgtc gttgatttcc cagcaccatt gagaccaatc
     9121 aaaccgacca actgcccact ttcaacagta aaggacacat ctttcaaaac aggaacatga
     9181 acatagccac ctgtcaggtt tttaatttct aacatatttt ctccaaatct ggtataatgt
     9241 agctatatta tatcaaaatt cagtacagta gaggtagatt ttatgtcaga ttgcattttt
     9301 tgtaaaatca tcgcagggga aattcctgct tcaaaagtat atgaagatga gcaggtcctt
     9361 gcctttcttg atatctctca agtaacacta ggacacacct tggtcgtgcc aaaagaacac
     9421 tatcgcaatc ttttggagat ggatgctacg agcgccagcc aactctttgc ccaagtacca
     9481 aaagtagctc aaaaagtcat gaaagtcact aaggctgctg gtatgaatat catttccaac
     9541 tgtgaagaag tcgctggtca aacagttttt catactcacg ttcaccttgt gcctcgctac
     9601 agtgctgacg atgacctcaa gattgatttt atcgcccacg aaccagactt tgacaaactt
     9661 gctcaagtcg ctgaaaccat caaaaacgct taaggagttg ctatgaaatt atccaaccta
     9721 ctgctatttg caggagctgc agccggaagt tatctggtta caaaaaatcg ccaaaccatc
     9781 acagatgaag tcttgaatac cactgaccgc gttcaagcta tcaaggacga tgtggatatt
     9841 atccaaaaca gcctgcaaat cattaaccag caaaaagaac ttatcaagga ataccaagaa
     9901 gacttgactt acaagtttaa ggtcttggaa aaggatatcc agactagact agctgtgata
     9961 aaagaaatgc agggaactga agataagtaa aaagagcccc ccggctcttt tttaaaacgt
    10021 aaacaagtta tagtgaattg aatttagaat agcacaccat agtttctaaa acattgttag
    10081 agattacttt aaaatcctct tatcaatttg ttcatattct atttcaatct attatatata
    10141 tcccatcaac tatgcatcat aatttaggta actcatactc aatgaaaatc aaaaagcaaa
    10201 ctaggaaact agccacgggc tgctcaaaac actgttttga ggttgtagat acgactcaca
    10261 tatatacggc aagccgacgc tgacgtggtt tgaagagatt ttcaaagagt attattctcc
    10321 atcaaaggca tctttaatat gatcaaagaa gccttttttc tttggattta ctttcaagtc
    10381 accagcagcc gcgaattctt tcaaggctac tttttggcgg tcgttcaagc ctgtcggtgt
    10441 tacgacatta acagtaacgt attggtcacc aactgcaccg ccacgaaggc tcggtgcccc
    10501 cttactacgt aggcggaatt tcttaccagt ctgagttccc tctggaataa ccaattcaac
    10561 atcaccgtga acagttggaa tatctactgt atcaccaaga gccgcttgga caaagttgag
    10621 gttgagattg tagaagatag tcgttccttc acgttcaaac ttgtcgctag cttctacaga
    10681 aactactaca tacaagtccc cataaggtcc accgttaaag cctgcttcgc cttgaccagc
    10741 gaggcgaatt tgttgacctg tttccacacc agcagggatt ttcacatgta cgctatgagc
    10801 ttgtttctca tgacctgttc catgacaggt tgtacatgga tatttgattt cttttcctcg
    10861 accgtgacag acatcacagg ttacttggcg acgcatcata ccaagaggag tctgcgtatc
    10921 gacgttaatg acaccagcgc catgacagcg tccacaagtg actggacttg tccctggctt
    10981 agcaccagag ccattacatg tacgacagcc agcttcacga tgatacttaa cttccttctc
    11041 agttccgaag atagcttctt caaaggtcaa attgacacga tactggagat catctccttg
    11101 gcgaggagcg tttggattgc gcgaagaacc gcctccgccg aagaaacttg agaaaatatc
    11161 ctcaaaacca ccgaagccac ctgccccatt gaaaccgccg aaaccaccag ctccaccaaa
    11221 accaccattg gcgcctgcag caccatactg gtcataggca gcacgttttt ggtcgtcact
    11281 caaagtctca taggcttctt gaacttcctt gtacttgtcc tcagcaccag gctccttgtt
    11341 gatatctggg tgatattttt tggaaagctt acgataagcc tttttgattt cgtctgccga
    11401 agcgtttttg gataccccca gacgatcata aaattcagta ttgttcataa ttcaagatac
    11461 aaagggcgtc aaacggacac agccatctag gagttttgac gacggacgct tatgtcctag
    11521 aaaaaactat ctttttggca cagtccgtag cccgtgttca gttacgaaca cccttattcc
    11581 tttctattga tgttctgaat cgaaccacca tttaggtcgg gttcaattcc tttcttttat
    11641 atttagtaag aaattctgaa acccgtgttc agttacaaac actctttgtt cctttctatt
    11701 gatgagacaa aacccaaaca aatgagattc cgtccctttt tatcgaaaaa cagaggctgg
    11761 gttgcaacct ctgcaaataa gtaaattaac tttattttga ttttaaatat cctataagta
    11821 cagaaatatt tatatatttt tgtctcttct tagtatttgc ctatataatt ccaattgatc
    11881 ataagaaata caactactgt ccaaatcata ccaattatga acggtattac aaatttatat
    11941 gtttgtattt ctaatgatat catagctgat accatcgccg atacaaatgc agacaacaat
    12001 actgaagtaa caaaattcct taccgcttca tcatttttga cacaactatc atgctcagct
    12061 aatataattt ctctatatat agtcaaacat tctactggaa tattatctat aaaacctttt
    12121 gctgcttcat agttgtcagc ttgattacaa aaatcattat aaacttttcg tgtatttttt
    12181 agatactcat catccaatac actcatctta tttttccgta aactctccgt ctacgacgtc
    12241 atcgcctgcg tttcctgttg cttgtgcgcc ttctgctcct tcttgagctt gttgcgctgc
    12301 tgcggcttgt tcgtagagtt tcacagcaag gccttgagct ttttcgttca acgcttcaag
    12361 tttcgctttc atgtcgtcca agttgttgtc ttcttgagct ttcttaaggt catcaagggc
    12421 agcttgggca gcgtcacgtt ctgcgtcgaa gcctttacct tcagtttcct tgattgtctt
    12481 ttcagtcgca aagattgctt ggtctacttc attacgaagg tctacttctt ctttacgttt
    12541 cttatcagct tcagcgtttg cttctgcatc tttcatcatg cggtcgattt cttcgtcagt
    12601 caaacctgag ttcgattgga tgacaatagt ttgttctttt tgagttccaa ggtctttggc
    12661 cttaacagac acgataccgt tcttgtcgat gtcaaatgtt acttcgattt gaggaattcc
    12721 acgaggtgca gctgggatat cagtcaattg gaagcgtcca agagtcttgt tatctgctgc
    12781 cattgggcgt tcaccttgaa gaacgtggat atcaacggct ggttggttgt ctgctgctgt
    12841 tgagaagact tgtgatttag atgttgggat tgtagtgttg cgatcgataa gttttgtaaa
    12901 tactccaccc attgtttcga taccaagtga caatggcgtt acatcaagaa ggacaacgtc
    12961 cttgacatca ccagtaatca caccaccttg gatagccgca cccatagcaa ctacttcatc
    13021 agggtttact gatttgtttg gttctttacc agtttcagct ttaacagctt caacaacggc
    13081 agggatacga gttgaaccac caacaaggat aacttcgtcg atttctgaca agctcaaacc
    13141 tgcatctgaa agggcttgac gaactggaac ttttgtacgt tcaacaaggt cacgagtcaa
    13201 atcgtcaaat ttcgcacgag tcaaagtcat ttccaagtga agaggtccag cttcacctgc
    13261 agtgataaat ggcaagctga tttgtgttga agttacacca gaaaggtctt tcttcgcttt
    13321 ttcagccgca tctttcaaac gttgcattgc catcttgtca gtagacaagt cgataccgtt
    13381 ttctttcttg aattctgcta ccaagtggtc aatgattttt tggtcaaagt cgtcaccacc
    13441 aagtttgttg tcccctgcag ttgacaatac gtcgaagaca ccgtcaccca attcaaggat
    13501 agagacgtcg aatgtaccac caccaaggtc aaataccaag attttttctt ctttgtcagt
    13561 cttgtccaaa ccataagcaa gagctgctgc agttggttcg ttaacaatac gttctacttc
    13621 aagaccagca attttaccag cgtcttttgt tgcttgacgt tgagcgtcgt tgaagtaagc
    13681 cggaactgtg ataacagctt tggttacttt ctcaccaagg tagtcttcag cgtagccttt
    13741 caagtattga aggatcatag ctgagatttc ttgtggagtg tattcttttc catttgcaga
    13801 aactttttca gaagttccca tcttagattt gatagagata actgtatctg ggtttgtgac
    13861 tgcttgacgt tttgcagcat caccaacgat gatttctccg tttttgaatg agactacaga
    13921 tggagttgtg cggtttcctt ctgggtttgc gatgattttg ctttcagttc cttcaagaac
    13981 tgcaactgct gagtttgttg tacctaagtc aataccgata attttagaca tgtgtttttc
    14041 tccttgttag ttaattttct atttttcttt ttgatactct tcttaagtgg cgacgccgtc
    14101 agagcttgac ttcgtcagtc tctttgacta aactttgagc ctaaggtctc aaaatttgcg
    14161 caaatagcgc cacggcgaag agtatcgtct ttggttcgct tcgctcacta ttacaaagca
    14221 aaacatattt tatctttctt catagtttat tgtcgtttcg gacaagtttt ctattatgta
    14281 aattgcgaca cgaggagtcg aaatcgattt tatttcgacg acgagttagt aaggaagcta
    14341 ggcaaacgcc atagcaattg ccgttttctg acgagttgct ttagctaccg tcagaattgc
    14401 cgaatcgaac acgccctaag ctctgagtaa aaaagataga ttttcttgtg ttcatcgaac
    14461 acttcgtcaa tctcctattt ttactgcgag ctttttacga gctttgtatc ttagttatac
    14521 accactacca ttgctgggcg taggatgcgg tcatggagtt tgtagccttt ttgaaagact
    14581 tgggcgatgg tatctactgg gtgttcatcg tctgctggga gagtttggat ggccatatgg
    14641 tagttatggt caaattcgcc atctgctgcg atttcttcaa ttccttcttc tttcaaagcg
    14701 tgaatcaagc tttcttgcac catccccaag cccttcttca catcatctgt caaaccttca
    14761 actgcaagtg cacgctcaag gttgtcaaga gatggtaaga ttgcttttgc caagtcctgg
    14821 ctacgataac gttgcaagtt ttgacgttct tcattggcac ggcgttggat attttgcatt
    14881 tctgcatgag cgcgaagata tttgttttcg aactcatctg cacgttcatt tgccaagtcc
    14941 aacttagact tttcaggagt tgtttcttca gctgtttcca caacttcctc ttcttgaact
    15001 tcttctactt cttcattttt tatatcttgg gccatgttcg cctcctttaa tgatttcaat
    15061 cttaatgtac ttcgtaatga ttactgctga ggtagcggta aaaatctgtc aacttcatag
    15121 tcaaaacacg gttgaccaca ttgacttgat tgattagctg ttggtaatcc agattaactg
    15181 gaccgataat ggctagaatt ccaactcctc gataaggaat gaggaactta ctactaatca
    15241 ccgctaggtc agctaaacag gactcttgac cgtctgcaac acgaacattt tgcatctgat
    15301 cctcacgcaa cccctcacga atctccaagg ccaccttttg cggttggtca aagaactgat
    15361 aagctgctag attggcaaaa ttcaagagat ttaccttgcc cgccaccaca atgttttcgt
    15421 tgaacatttc cttaaagatg tgttcaaaga gatcgatcac attatccgtt gttgtgaagt
    15481 aacgctggat aatctgcgga atctccgtcc gaatcttgta gtgaatatct agaacggtgt
    15541 ggccgaggaa acgttcctga atgatgctct tcagtttcag caaatcctcc tgcaaaaagt
    15601 tccttggaat cagaaactga ctagtaaccg ttcgagactc gtctagggta aatactgcca
    15661 aggctgtatg ttgccccaaa acaacgatat caaaggctgt cagacgttgt ctgctcggct
    15721 caacatccag tgctactacc gtacagccac tcaagtctgt cagtagatta gcagcctctt
    15781 gcagaatatc ctccagtttg aagaattcct gatcaaagga tttgacaatc tcgtatacct
    15841 cattttcagc cagtcggtca aaatccagtg agtgtttcac ataatactga aaaccagcaa
    15901 cacttggcat ccgaccactt gaagtatgag ccttctcaag caaaccttgc ttttctagag
    15961 ctgccatatc attacgaatg gttgcactgc tagagttaat agactcttgc aaagctttgg
    16021 atccgacagg ttcgtgcgtt ttggtaaaga tgtcaataat cagatttaga atatcctgct
    16081 gacgctctgt aaccatctca tcactcctct ctgtctgatc gattagcact cgatacgctc
    16141 aagtgctaac ttatgattct attatacacc cttagaagag aatgtcaaga taaaaactca
    16201 aaaaattagc actcttttat taagagtgct aaaaatcagc ctacagaccg agaaactcac
    16261 cttccatcta cttggtattt ccttttaagt ctaaaaaaac catagattag ataagaaatc
    16321 aagaaagcat ataaaagaaa aataacgaag aaagacatag aaagttcttc tttaaacaaa
    16381 ctcatacaaa caaccaaacc acctaagaaa gtagctgtac aggaacgaag tctatatcgc
    16441 ataacttccc atctaatccc cttactcata tagacttgat cctctggaag taaatcagaa
    16501 gacgatttac gaagaatcga acaagaacct gctcctatca attcccaacc tctattgcta
    16561 aaatcttgca gttcatgctt atatttttta agaaatctag aatcatagat acggtagatg
    16621 acatcgtctg gttgacattg gtcaaaatag aacaaaccaa aacgactcgt tctatatctc
    16681 caacccttca aatgcatctc atgtaaatat tcttcttact tgtccaaatc aacaatggtg
    16741 aaaatccgaa attctactct gctattcatt gtcttacccc aaaattagaa aacatgcctg
    16801 gcgttattta ttagataatt ctttccactt ttgactcaat ctccaaaaaa tataagaaat
    16861 ctgaatcgca aaaactatca ataaaaccca atctattatg aaagtcaaaa acactttcca
    16921 actgaaagaa ctacctccag tgacaaactt tgagaaaaac ggtagtagag ctaaaaagag
    16981 aagtaaaata ggaagcatcc gcattgttaa aatccgtttg gcataaaaaa atctttattt
    17041 aaactaaaat attatagcaa aatttacgcc agtttttgaa cggctgatgt agatatttta
    17101 tactttcaaa atgtttaaat gtgattattt atttttgaaa aatagctcac cagcccgact
    17161 gaaagtgctt atagaatgat aataagtcgc ctgccgaaaa cagcggaaaa tagcggtgtt
    17221 atgcggagat aatctgacgc gatgcgaaag tatattgcat acttattttc aacaatttag
    17281 cagagtattt ttataagtgt gatataatag aagtataatt tgttctgata gtttatttta
    17341 tggagaagta gatttttaga atgcggaggg ttcaatatgg ttgagtttat aaagtctaag
    17401 aaagaaatga gtgaggagga tattaaagca aatttcatca ctcctgctat tgtatccaaa
    17461 ggatggaaaa atggtgagca tatcgcttac gaagaatact tcactgatgg tcgaattgag
    17521 gttagaggag ataaggctcg tcgtaaagaa ggaaaaaaat cagactattc actgtattac
    17581 caatttggaa ctcgaattgc aattgttgag gcaaaggata ataaacacag cgttcgagca
    17641 ggattacaac aagctattga atatggagag attttagatg ttccatttgt ttattcttcg
    17701 aatggtgatg gctttattga acacgaccgt atcacgagag aagaacgtga gctggagtta
    17761 gacgaattcc ctactcgtga agaattattt tctcgtatga cgaaggaaaa aggattgacg
    17821 tacgaaatta cagaagctat ctcaactcca tactatacag acgccttctc aatgaaaacg
    17881 ccacgctatt atcagcaaat agctatcaac cgtactattg aaacagttgc cagaggacaa
    17941 aaacgagtaa tgtttgtgat ggcaacagga acggggaaaa cgttcatggc ttttcaaatt
    18001 attcatcgcc ttcgaaaagc tggtttggct aaacgagttt tattcttagc ggatagaaac
    18061 atcttagtag accaaacgat ggctgaagac tttaggccat tcgaaaaggt aatgacgaaa
    18121 attacaccaa aacttttgac tgctcctgaa aaattaaatt cttttgaaat ttatctaggg
    18181 ctttatcagc aactaactgg tgaagatgga actgaaacac attatcaaaa atttgataaa
    18241 gacttctttg atttaatcgt aattgatgaa gcgcaccgtg gttcagctaa ggaaaacagt
    18301 aactggcgta agataattga ttatttcagt tctgcgacac agattgggat gaccgctact
    18361 cctaaagaaa ccaagaatgc ttccaatacg gaatactttg gtgagccaat ctatacttat
    18421 agtttaaaac agggaatcga ggatggtttt ttggctccat atcgtgttat gagggttaat
    18481 ttagatgtgg atgtggatgg ttatcgtcca gaaactggaa aagttgatac taacggacaa
    18541 ttaatagaag ataggtacta cggcaggaaa gattttgata aaaccattgt cattgatgat
    18601 agaacgcaaa gagttgccaa gtttgtttct gattatatga agcaaaacaa tgcacgattt
    18661 gataaaacaa ttgttttttg tgttgatatt gaccatgccg agcgaatgcg tgctgcactt
    18721 gtaaaagaga atctagactt agtccaagaa gactatcgtt atgtcatgca agtaactggt
    18781 gacaacgctg aaggaaaagc tcaactggat aactttatgg atgtcaattc taattttccc
    18841 gctatggtaa caacgtctaa attattaacg acaggagtta atgctaaaac atgtcgtttg
    18901 attgttttag actctaatat ccaatccatg actgaattta aacaaattat tggtcgtggc
    18961 acacgtcttt atcctcaaaa ggggaaagaa ttttttacga ttattgattt tcgaaatgtt
    19021 accaatttgt ttgctgaccc tgattttgat ggtgagccag tgaaggtgct ggaaacaggt
    19081 gcgaaaacag tcagtggttc cacgcccggt ttcgtagatg aggaaggtga cccagtagaa
    19141 aaatatatcg ttacagacaa gcaggttacc attcttaatt ctactgttca agtattggat
    19201 gaaaacggga aactgattac cgaaagcctg accgactaca ctcggaagaa tatcttaggt
    19261 agctacgcca ctttgaacga ttttatcaca gtttggcata cggcggataa aaagaagctt
    19321 atcttagacg aactttataa aaaaggagtt tatctagatg ctattcgaga gtcggaggga
    19381 atatcagaac aagaaatcga tgattttgat ttactcctaa aacttgccta tggtcaaaaa
    19441 gaattaacca aaacggaacg tatcaataaa ctcaaacaaa gcggatattt atataaatat
    19501 agtgaggaag cgcgtgctgt tttggaaatt ttactgaaca aatacatgga taaaggtatt
    19561 ggagaactcg aaagcattga aacattaaaa cttccagaat ttcagatata tggtggaacc
    19621 ttcaaaatca tcaatactta ttttggagat aaaaaacgat atttacaagc aattaaagaa
    19681 ttggagcaag agctatttac agtagcttaa tgaaaggaaa gtatgtcaat tacatcattt
    19741 gtaaaaagaa ttcaagatat cactcgaaac gatgctggtg ttaatggtga tgctcaacgt
    19801 attgagcaaa tgtcttggtt attattctta aaaatttatg atagccgtga aatggtttgg
    19861 gaattagaag aagacgagta tgagtcaatt atcccagagg aattaaaatg gcgaaattgg
    19921 gctcatgctc aaaatgggga acgggtattg acaggcgatg aattacttga ttttgtcaat
    19981 aacaagttat tcaaagagtt gaaagagctt gaaataactt caaatatgcc tattcgaaaa
    20041 acgattgtta aatcagcttt tgaagatgcg aacaactata tgaaaaatgg cgtcttgtta
    20101 cgccaagtca tcaatgttat tgatgaagtt gatttcaata gccctgaaga tcgtcattcg
    20161 tttaatgata tttacgaaaa aattcttaaa gatattcaaa atgctgggaa ctcaggagaa
    20221 ttttatacgc cacgtgcagc gactgatttt attgccgaag ttcttgaccc aaaacttgga
    20281 gaatcaatgg cagaccttgc ttgcggaaca ggaggcttct tgacttcgac tctgaaccgt
    20341 ttaagtagtc aacgtaaaac tagtgaagat accaaaaaat ataatacagc tgtttttggt
    20401 attgaaaaga aagcatttcc tcatctttta gcagttacaa atctgtttct tcacgaaatt
    20461 gatgacccta aaattgttca tggaaatact ttggagaaaa atgttcgtga atatacggat
    20521 gatgaaaaat ttgacattat tatgatgaat ccaccttttg gagggtcaga attagaaaca
    20581 ataaaaaata actttccagc agaattacgg agttctgaaa cagctgattt atttatggct
    20641 gtcattatgt atcgtttgaa agaaaatggt cgtgttggag ttattttacc tgatggtttt
    20701 ctatttggtg aaggtgtaaa aactcgcttg aaacaaaaac tggtagatga gttcaactta
    20761 catacgatta ttaggttgcc tcatagtgtc tttgcaccgt atacaggaat ccatacgaac
    20821 attcttttct ttgataaaac aaagaaaaca gaagaaactt ggttttatcg tttagatatg
    20881 ccagatggtt ataaaaattt ctcgaaaact aagccgatga agtcagaaca cttcaatcct
    20941 gttcgtgact ggtgggaaaa tcgtgaagag attctggaag gtaagttcta caaatctaaa
    21001 tcatttacac ctagtgaatt ggctgagttg aattataatt tagaccagtg tggctttcca
    21061 aaagaggaag aggaaatctt aaatcccttt gagttgattc agaattatca agcggaaaga
    21121 gcaactttaa atcataagat tgataatgta ttagctgata ttttgcagtt gttggaggac
    21181 aaataatgac accagaacaa cttaaagcaa gtattctcca aagagcgatg gaagggaaat
    21241 tagtgccgca aaatcccaat gacgaacctg caagtgaatt attaaagaga attaaagctg
    21301 aaaaagaaaa acttatcagt gaaggaaaaa tcaaacgaga taaaaaggaa actgagatat
    21361 ttcgtggtga tgatgggaaa cattatggga agtttgctga tggaagtact caagaaattg
    21421 atgttcctta tgatattcct gatacttggg agtgggtgag gataaaatca atttattgga
    21481 attttggaca aaataagcca gagaaatcct ttaggtatat agatacgtct agtattgata
    21541 gaaaaaagaa tataatcaac tacaaaaatc tacaatatct ttcacctgaa caagcgcctt
    21601 cccgtgctag aaaattagtt tcgcagaata gtgtcttatt ttcaacagtt agaccatatc
    21661 taaaaaatat tgctgtagtt agagaactta aagagtattt gatagctagt acagcattta
    21721 ttgttttgga tactttactt aacgaaacat atttgaaata ttatttatta tcagataatt
    21781 ttatcaatcg tgttaataat aaatctactg gaacaagtta tcctgcaatc aatgattata
    21841 attttaatct attattaatt gctctccccc cactatccga acaacaacgc ata
//
LOCUS       DAVLXH010000034        21573 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00028199
            SAMN33607166-rid17955573.denovo.034, whole genome shotgun sequence.
ACCESSION   DAVLXH010000034 DAVLXH010000000
VERSION     DAVLXH010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607166
            Sequence Read Archive: SRR23725544
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21573)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21573)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721421.1
            Genome Coverage       :: 115x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:42:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,210
            CDSs (total)                      :: 2,161
            Genes (coding)                    :: 2,023
            CDSs (with protein)               :: 2,023
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 73 of 138
            Pseudo Genes (incomplete)         :: 60 of 138
            Pseudo Genes (internal stop)      :: 40 of 138
            Pseudo Genes (multiple problems)  :: 31 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21573
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607166-rid17955573.denovo.034"
                     /strain="AUSMDU00028199"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1349"
     gene            complement(<1..1961)
                     /locus_tag="VYO11_001410"
     CDS             complement(<1..1961)
                     /locus_tag="VYO11_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RICH domain-containing protein"
                     /protein_id="HEV1595959.1"
                     /translation="MFASKSERKVHYSIRKFSIGVASVVVASLFLGGVVHAEEVRRGN
                     NLTVTSSGDEVESHYQSILEKVRKSLEKDRHTQNVDLIKKLQDIKRTYLYSLKEKPEA
                     ELTSKTKKELTAAFEQFKKDTLKSGKKVAEAEKKAKAQKEEDRRNYPTNTYKTIELEI
                     AEAEVGVAKAELELEFAQAQVQIPQDTEKINAAKSKVEAAKSNVKKLEKIKSDIEKTY
                     LSKLDNSTKETPKSRVRRNSPQVGDSRELKETIDKAKETLSTYMVTRLTKLDPSVFWF
                     ADLLMDAKKVVEEYKTKLEDASDKKSVEDLRKEAEGKIESLIVTHQNREKENQPAPQP
                     GGQAGGSMVVPPVTQTPPSTSQSPGQKATEAEKKKLQDLIRQFQEALNKLDDETKTVP
                     DGAKLTGEAGKAYNETRTYAKEVVDKSKKLLSQTAVTMDELAMQLTKLNDAMSKLKEA
                     KAKLVPEVKPQPENPEPKPQPEGEKPSVPDINQEKEKAKLAIATYMSKILDDIKKHHL
                     KKEKHHQIVALIKDLDKLKKQALSEIDNVNTKVEIENTVHKVFADMDTVVTKFQKGLI
                     QNTPQVPEAPKAPDTPQIPEAPAPETPKTGWKQENGMWYFYNTDGSMATGWLEYNGSW
                     YYLNANGAMATGWLEYNGSWYYLNTNGAM"
     gene            complement(2040..2567)
                     /locus_tag="VYO11_001411"
     CDS             complement(2040..2567)
                     /locus_tag="VYO11_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenylcysteine carboxyl methyltransferase
                     family protein"
                     /protein_id="HEV1595960.1"
                     /translation="MVLAIILVTFLIRLIFLKRSIENEKRILSNGGKEFGVENTKRLT
                     MAHIVFYLSCLVEAMVHKTIFDGMGMVGLVLLIFSMLMLMLVIHLLGDIWTVKLMLVN
                     NHKYVDHILFRTVKHPNYFLNILPELIGLTLLSHAYMTFVLVFPVYAVILYRRIAEEE
                     KLLHEVIIPNGSIKR"
     gene            complement(2650..3990)
                     /gene="hk06"
                     /locus_tag="VYO11_001412"
     CDS             complement(2650..3990)
                     /gene="hk06"
                     /locus_tag="VYO11_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     HK06"
                     /protein_id="HEV1595961.1"
                     /translation="MIKNPKLLTKSFLRSFAILGGVGLVIHIAIYLTFPFYYIQLEGE
                     KFNESARVFTEYLKTKTSDEIPSLLQSYSKSLTISAHLKRDIVDKRLPLVHDLDIKDG
                     KLSNYIVMLDMSVSTADGKQVTVQFVHGVDVYKEAKNILLLYLPYTFLVTIAFSFVFS
                     YFYTKRLLNPLFYISEVTSKMQDLDDNIRFDESRKDEVGEVGEVGKQINGMYEHLLKV
                     IHELESRNEQIVKLQNQKVSFVRGASHELKTPLASLRIILENMQHNIGDYKDHPKYIA
                     KSINKIDQMSHLLEEVLESSKFQEWTECRETLTVKPVLVDILSRYQELAHSIGVTIEN
                     QLTDATRVVMSLRALDKVLTNLISNAIKYSDKNGRVIISEQDGYLSIKNTCAPLSDQE
                     LEHLFDIFYHSQIVTDKDESSGLGLYIVNNILESYQMDYSFLPYEHGMEFKISL"
     gene            complement(3987..4640)
                     /gene="rr06"
                     /locus_tag="VYO11_001413"
     CDS             complement(3987..4640)
                     /gene="rr06"
                     /locus_tag="VYO11_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001024075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RR06"
                     /protein_id="HEV1595962.1"
                     /translation="MNILVADDEEMIREGIAAFLTEEGYHVIMAKDGQEVLEKFQDLP
                     IHLMVLDLMMPRKSGFEVLKEINQKHDIPVIVLSALGDETTQSQVFDLYADDHVTKPF
                     SLVLLVKRIKALIRRYYVIEDLWRYQDVTVDFTSYKAHYKNEEIDLKPKELLVLKCLI
                     QHKNQVLSREQILEEISKDVADLPCDRVVDVYIRTLRKKLALDCIVTVKNVGYKISL"
     gene            complement(5282..7714)
                     /locus_tag="VYO11_001414"
     CDS             complement(5282..7714)
                     /locus_tag="VYO11_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001109706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEV1595963.1"
                     /translation="MNYSKALNECIESAYMVAGHFGARYLESWHLLIAMSNHSYSVAG
                     ATLNDYPYEMDRLEEVALELTETDYSQDETFTELPFSRRLQVLFDEAEYVASVVHAKV
                     LGTEHVFYAILHDGNALATRILERAGFSYEDKKDQVKIATLRRNLEERAGWTREDLKA
                     LRQRHRTVADKQNSMANMMGMPQTPSGGLEDYTHDLTEQAHSGKLEPVIGRDKEISRM
                     IQILSRKTKNNPVLVGDAGVGKTALALGLAQRIASGDVPAEMAKMRVLELDLMNVVAG
                     TRFRGDFEERMNNIIKDIEEDGQVILFIDELHTIMGSGSGIDSTLDAANILKPALARG
                     TLRTVGATTQEEYQKHIEKDAALSRRFAKVTIEEPSVADSMTILQGLKATYEKHHRVQ
                     ITDEAVETAVKMAHRYLTSRHLPDSAIDLLDEAAATVQNKAKHVKADDSDLSPADKAL
                     MDGKWKQAAQLIAKEEEVPVYKDLVTESDILTTLSRLSGIPVQKLTQTDAKKYLNLEA
                     ELHKRVIGQDQAVSSISRAIRRNQSGIRSHKRPIGSFMFLGPTGVGKTELAKALAEVL
                     FDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVE
                     KAHPDIFNVLLQVLDDGVLTDSKGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAKDI
                     RFDQENMEKRMFEELKKAYRPEFINRIDEKVVFHSLSSDHMQEVVKIMVKPLVASLAE
                     KGIDLKLQASALKLLANQGYDPEMGARPLRRTLQTEVEDKLAELLLKGDLVAGNTLKI
                     GVKAGQLKFDIA"
     gene            complement(7716..8174)
                     /locus_tag="VYO11_001415"
     CDS             complement(7716..8174)
                     /locus_tag="VYO11_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HEV1595964.1"
                     /translation="MRFKNTSDHIEAYIKAILDQSGIVELQRSQLADTFQVVPSQINY
                     VIKTRFTESRGYLVESKRGGGGYIRIGRIEFSSHHEMLRELLYSIGERVSQEIYEDIL
                     QLLVEQELMTKQEMNLLESVALDRVLGEEAPVVRANMLRQIIQEVDRKGK"
     gene            complement(8293..9021)
                     /locus_tag="VYO11_001416"
     CDS             complement(8293..9021)
                     /locus_tag="VYO11_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1595965.1"
                     /translation="MTEIRLEHVSYAYGQERILEDINLQVTSGEVVSILGPSGVGKTT
                     LFNLIAGILEVQSGRIVLDGEENPKGRVSYMLQKDLLLEHKTVLGNIILPLLIQKVDK
                     AEAISRADKILATFQLTAVRDKYPHELSGGMRQRVALLRTYLFGHKLFLLDEAFSALD
                     EMTKMELHAWYLEIHKQLQLTTLIITHSIEEALNLSDRIYILKNRPGQIVSEIKLDWS
                     EDEDKEVQKIAYKRQILAELGLDK"
     gene            complement(9021..10028)
                     /locus_tag="VYO11_001417"
     CDS             complement(9021..10028)
                     /locus_tag="VYO11_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEV1595966.1"
                     /translation="MKKTWKVFLTLVTALVAVVLVACGQGTASKDNKEAELKKVDFIL
                     DWTPNTNHTGLYVAKEKGYFKEAGVDVDLKLPPEESSSDLVINGKAPFAVYFQDYMAK
                     KLEKGAGITAVAAIVEHNTSGIISRKSDNVSSPKDLVGKKYGTWNDPTELAMLKTLVE
                     SQGGDFEKVEKVPNNDSNSITPIANGVFDTAWIYYGWDGILAKSQGVDANFMYLKDYV
                     KEFDYYSPVIIANNDYLKDNKEEARKVIQAIKKGYQYAMEHPEEAADILIKNAPELKE
                     KRDFVIESQKYLSKEYASDKEKWGQFDAARWNAFYKWDKENGILKEDLTDKGFTNEFV
                     K"
     gene            complement(10067..10825)
                     /locus_tag="VYO11_001418"
     CDS             complement(10067..10825)
                     /locus_tag="VYO11_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009013602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1595967.1"
                     /translation="MRNLRSILRRHISLLGFLGVLLIWQLAGFLKLLPKFILPTPLEI
                     LQPFVRDREFLWHHSWATLRVALLGLILGVLIACLMAVLMDSLTWLNDLIYPMMVVIQ
                     TIPTIAIAPILVLWLGYGILPKIVLIILTTTFPIIVSILDGFRHCDKDMLTLFSLMRA
                     KPWQILWHFKIPVSLPYFYAGLRVSVSYAFITTVVSEWLGGFEGLGVYMIQSKKLFQY
                     DTMFAIIILVSIISLLGMKLVDISEKYVIKWKRS"
     gene            complement(10788..11078)
                     /locus_tag="VYO11_001419"
     CDS             complement(10788..11078)
                     /locus_tag="VYO11_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000647657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine-binding protein"
                     /protein_id="HEV1595968.1"
                     /translation="MKASIALQVLPLAQGIDRIAVIDQVIAYLQTQEVTMVVTPFETV
                     LEGEFDELMRILKEALEVAGQEADNVFANVKINVGEILSIDEKLEKYTETTH"
     regulatory      complement(11149..11251)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(11334..12680)
                     /gene="cbpD"
                     /locus_tag="VYO11_001420"
     CDS             complement(11334..12680)
                     /gene="cbpD"
                     /locus_tag="VYO11_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase CbpD"
                     /protein_id="HEV1595969.1"
                     /translation="MKILPFIARGTSYYLKMSVKKLVPFLVVGLMLAAGDSVYAYSGG
                     NGSIARGDDYPAYYKNGSQEIDKWRMYSRQCTSFVAFRLSNVNGFEIPAAYGNANEWG
                     HRARREGYRVDNTPTIGSITWSTAGTYGHVAWVSNVMGDQIEIEEYNYGYTESYNKRV
                     IKANTMTGFIHFKDLDGGSVGNSQSSASTGGTHYFKTKSAIKTEPLVSATVIDYYYPG
                     EKVHYDQILEKDGYKWLSYTAYNGSYRYVQLEAVNKNPLGNSVLSSTGGTHYFKTKSA
                     IKTEPLVSGTVIDYYYPGEKVHYDQILEKDGYKWLSYTAYNGSRRYIQLEGVTSSQNY
                     QNQSGNISSYGSNNSSTVGWKKINGSWYHFKSNGSKSTGWLKDGSSWYYLKLSGEMQT
                     GWLKENGSWYYLGSSGAMKTGWYQVSGKWYYSYSSGALAVNTTVDGYRVNSDGERV"
     gene            complement(12769..13035)
                     /locus_tag="VYO11_001421"
     CDS             complement(12769..13035)
                     /locus_tag="VYO11_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001278167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1595970.1"
                     /translation="MSDAFTDVAKMKKIKEEIKAHEGQVVEMTLENGRKRQKNRLGKL
                     IEVYPSLFIVEFGDVEGDKQVNVYVESFTYSDILTEKNLIHYLD"
     gene            complement(13037..14389)
                     /gene="dnaB"
                     /locus_tag="VYO11_001422"
     CDS             complement(13037..14389)
                     /gene="dnaB"
                     /locus_tag="VYO11_001422"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HEV1595971.1"
                     /translation="MAEVEELRVQPQDILAEQSVLGAIFIDESKLVFVREYIESRDFF
                     KYAHRLIFQAMVDLSDRGDAIDATTVRTILDNQGDLQNIGGLSYLVEIVNSVPTSANA
                     EYYAKIVAEKAMLRRLIVKLTESVNQAYEASQPADEIIAQAEKGLIDVSENANRSGFK
                     NIRDVLNLNFGNLEARSQQTTDITGIATGYRDLDHMTTGLHEEELIILAARPAVGKTA
                     FALNIAQNIGTKLDKTVAIFSLEMGAESLVDRMLAAEGLVESHSIRTGQLTDEEWQKY
                     TIAQGNLANASIYIDDTPGIRITEIRSRSRKLAQETGNLGLILIDYLQLITGTGRENR
                     QQEVSEISRQLKILAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYERGGEEEEGIPNNKVEVIIEKNRSGARGTVELIFQKEYNKFSSISKREA
                     "
     gene            complement(14432..14884)
                     /gene="rplI"
                     /locus_tag="VYO11_001423"
     CDS             complement(14432..14884)
                     /gene="rplI"
                     /locus_tag="VYO11_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HEV1595972.1"
                     /translation="MKVIFLADVKGKGKKGEIKEVPTGYAQNFLIKKNLAKEATAQAV
                     GELRGKQKSEEKAHAEMIAEGKAIKAQLEAEETVVEFVEKVGPDGRTFGSITNKKIAE
                     ELQKQFGIKIDKRHIQVQAPIRAVGLIDVPVKIYQDITSVINLRVKEG"
     gene            complement(14881..16854)
                     /locus_tag="VYO11_001424"
     CDS             complement(14881..16854)
                     /locus_tag="VYO11_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HEV1595973.1"
                     /translation="MKKFYVSPIFPILVGLIAFGVLSTFIIFVNNNLLTVLILFLFVG
                     GYVFLFKKLRVHYTRSDVEQIQYVNHQAEESLTSLLEQMPVGVMKLNLSSGEVEWFNP
                     YAELILTKEDGDFDLEAVQTIIKASVGNPSTYAKLGEKRYAVHMDASSGVLYFVDVSR
                     EQAITDELVTSRPVIGIVSVDNYDDLEDATSESDISQINSFVANFISEFSEKYMMFSR
                     RVSMDRFYLFTDYTVLEGLMNDKFSVIDAFREESKQRQLPLTLSMGFSYGDGNHDEIG
                     KVALLNLNLAEVRGGDQVVVKENDETKNPVYFGGGSAASIKRTRTRTRAMMTAISDKI
                     RSVDQVFVVGHKNLDMDALGSAVGMQLFASNVIENSYALYDEEQMSPDIERAVSFIEK
                     EGVTKLLSVKDAMGMVTNRSLLILVDHSKTALTLSKEFYDLFTQTIVIDHHRRDQDFP
                     DNAVITYIESGASSASELVTELIQFQNSKKNRLSRMQASVLMAGMMLDTKNFTSRVTS
                     RTFDVASYLRTRGSDSIAIQEIAATDFEEYREVNELILQGCKLGSDVLIAEAKDTKCY
                     DTVVISKAADAMLAMSGIEASFVLAKNTQGFISISARSRSKLNVQRIMEELGGGGHFN
                     LAAAQIKDVTLSEAGEKLTEIVLNEIKEKEKEE"
     gene            complement(16990..17538)
                     /gene="raiA"
                     /locus_tag="VYO11_001425"
     CDS             complement(16990..17538)
                     /gene="raiA"
                     /locus_tag="VYO11_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000599099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HEV1595974.1"
                     /translation="MIKYSIRGENLEVTEAIRDYVVSKLEKIEKYFQPEQELDARINL
                     KVYREKTAKVEVTIPLGSITLRAEDVSQDMYGSIDLVTDKIERQIRKNKTKIERKNKN
                     KVATGQLFTDALVEDSNVVQSKVVRSKQIDLKPMDLEEAILQMDLLGHDFFIYVDVED
                     QTTNVIYRREDGEIGLLEVKES"
     gene            complement(17618..18280)
                     /locus_tag="VYO11_001426"
     CDS             complement(17618..18280)
                     /locus_tag="VYO11_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HEV1595975.1"
                     /translation="MKCLLCGQTMKTVLTFSSLLLLRNDDSCLCSDCDSTFERIGEEN
                     CPNCMKTELSTKCQDCQLWCKEGVEVSHRAIFTYNQAMKDFFSRYKFDGDFLLRKVFA
                     SFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEAAGFEYLDLLEKREERASSS
                     KNRSERLGTELPFFIKSGVTIPKKILLIDDIYTTGATINRVKKLLEEAGAKDVKTFSL
                     VR"
     gene            complement(18277..19575)
                     /locus_tag="VYO11_001427"
     CDS             complement(18277..19575)
                     /locus_tag="VYO11_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEV1595976.1"
                     /translation="MKVNLDYLGRLFTENELTEEERQLAEKLPAMRKEKGKLFCQRCN
                     STILEEWYLPIGAYYCRECLLMKRVRSDQTLYYFPQEDFPKQDVLKWRGQLTPFQEKV
                     SEGLLQAVDKQKPTLVHAVTGAGKTEMIYQVVAKVINAGGAVCLASPRIDVCLELYKR
                     LQQDFSCGIALLHGESEPYFRTPLVVATTHQLLKFYQAFDLLIVDEVDAFPYVDNPML
                     YHAVKNSVKENGLRIFLTATSTNELDKKVRLGELKRLNLPRRFHGNPLIIPKPIWLSD
                     FNRYLDKNRLSPKLKSYIEKQRKTAYPLLIFASEIKKGEQLAEILQEQFPNEKIGFVS
                     SVTEDRLEQVQAFRDGELTILISTTILERGVTFPCVDVFVVEANHRLFTKSSLIQIGG
                     RVGRSMDRPTGDLLFFHDGLNASIKKAIKEIQMMNKEAGL"
     gene            19631..20266
                     /locus_tag="VYO11_001428"
     CDS             19631..20266
                     /locus_tag="VYO11_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HEV1595977.1"
                     /translation="MEFRTIKEDGQVQEEIKKSRFICHAKRVYSEEEARDFITAIKKE
                     HYKATHNCSAFIIGERSEIKRTSDDGEPSGTAGVPMLGVLENHNLTNVCVVVTRYFGG
                     IKLGAGGLIRAYAGSVALAVKEIGIIEIKEQAGIAIQMSYAQYQEYSNFLKEHDLMEL
                     DTNFTDQVDTMIYVDKEEKETIKAALVEFFNGKVTLTDQGLREVEVPVNLV"
     gene            20551..21477
                     /gene="cysK"
                     /locus_tag="VYO11_001429"
     CDS             20551..21477
                     /gene="cysK"
                     /locus_tag="VYO11_001429"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HEV1595978.1"
                     /translation="MSIYNNITELIGQTPIVKLNNIVPEGAADVYIKLEAFNPGSSVK
                     DRIALSMIEKAEQDGILKPGSTIVEATSGNTGIGLSWVGAAKGYKVVIVMPETMSVER
                     RKIIQAYGAELVLTPGSEGMKGAIAKAQEIAAERDGFLPLQFDNPANPEVHERTTGAE
                     ILAAFGKDGLDAFVAGVGTGGTISGVSHALKSENSNIQVYAVEADESAILSGEKPGPH
                     KIQGISAGFIPDTLDTKAYDGIVRVTSDDALALGREIGGKEGFLVGISSAAAIYGAIE
                     VAKKLGTGKKVLALAPDNGERYLSTALYEFEV"
BASE COUNT         6312 a         4878 c         3567 g         6816 t
ORIGIN      
        1 tccatagcac cattagtatt gaggtagtac catgaaccat tgtattctag ccaacctgtt
       61 gccatagcac cattagcgtt gagatagtac catgagccat tgtattctag ccagcctgtt
      121 gccattgaac catcagtatt gtagaagtac cacataccgt tttcttgttt ccagcctgtt
      181 tttggagttt ctggagctgg tgcttccgga atttgcggtg tgtctggagc ctttggtgct
      241 tctggaacct gcggtgtgtt ctgaattaag cctttttgga atttagtaac aaccgtatcc
      301 atgtctgcaa ataccttgtg gactgtattc tcaatttcta ctttggtatt tacattatca
      361 atttcagaaa gtgcttgctt tttaagttta tcaaggtcct taataagagc aacaatctga
      421 tgatgttttt ctttcttcag atgatgtttc tttatatcat ctaaaatctt gctcatgtat
      481 gttgctatag caagtttagc tttttctttc tcctgattaa tatctggtac gcttggtttc
      541 tcaccctctg gttgtggttt tggctctggg ttttccggct gtggtttaac ctctggtacc
      601 aatttcgctt tagcttcttt caatttagac atggcatcgt tcaatttggt taattgcatt
      661 gccaattcat ccattgtcac tgctgtctgt gatagaagct tcttgctttt gtcaacaact
      721 tctttcgcat aagttctagt ctcattatag gcttttccag cttctcctgt gagtttagcc
      781 ccatctggaa cagtctttgt ttcatcgtct agtttgttca aggcttcttg gaattgacga
      841 atcaagtctt gtaacttttt cttttcagct tcggtcgcct tttgtcctgg actttgggaa
      901 gttgatggag gtgtttgcgt caccggtggt acaaccattg aaccacctgc ttgtcctcct
      961 ggttggggtg ctggttggtt ttctttttct ctattttggt gagtcacgat aagagactct
     1021 atttttcctt ctgcttcctt tcgcaagtct tctaccgatt ttttatctga agcatcctct
     1081 aattttgtct tgtattcttc cacaaccttc ttagcatcca taagaagatc tgcaaaccaa
     1141 aaaacagatg gatccagctt cgttaaacga gttaccatat aggtagacag agtttctttc
     1201 gctttgtcta tcgtttcctt aagttctctc gaatcgccta cttgcggaga atttcttcgc
     1261 actctagatt ttggcgtttc tttggttgag ttatctaatt tagacaaata cgttttttca
     1321 atatctgatt taattttttc tagtttttta acattacttt tagcagcttc tactttagat
     1381 ttagcagcat taattttctc agtatcttga ggtatttgaa cttgagcttg tgcaaactca
     1441 agctcaagct ctgccttggc gacccctact tctgcttccg caatttccag ttcgattgtt
     1501 ttgtaagtat tggttgggta gttacggcga tcttcttctt tttgagcttt ggcttttttc
     1561 tcagcttctg ctaccttttt tcctgatttc aatgtatctt ttttaaactg ctcaaaagct
     1621 gcggttaact ctttttttgt ttttgacgtc aactcagctt ccggcttctc ttttaaacta
     1681 tacaaatacg ttctcttaat gtcttgcaac tttttgatta agtcgacatt ttgggtatgt
     1741 cgatcttttt ccaaactttt tctgaccttc tccaatatac tttgataatg cgactcgact
     1801 tcatccccac tagatgtaac cgtgaggtta ttccctcttc taacctcttc tgcatgaact
     1861 actcctccta agaacaaact agcaactact acactagcta ctccaatact aaatttacga
     1921 attgaataat gtacttttct ttcgcttttt gatgcaaaca tgtttatttc cttctatatt
     1981 ttttctttaa ccttactata tcacttcaat atgaactgta tataaatcga attttgtatt
     2041 tatctcttta tgcttccatt tgggattata acttcatgta atagcttttc ctcttcagct
     2101 attcgtcgat acaaaataac tgcataaact ggaaaaacta aaacaaaagt catataggca
     2161 tgactcaaca aggtcaagcc aatcaactca ggtaaaatat ttaaaaagta attaggatgt
     2221 tttactgtcc taaacaagat atgatctaca tatttgtgat tattgacaag cataagcttc
     2281 actgtccaaa tatctcccaa caagtgaatc accaacatta acatcagcat agaaaaaata
     2341 agcaagacta aaccaaccat gcccatgcca tcaaaaattg tcttgtgcac cattgcctca
     2401 accaagcaag agagataaaa aacaatatga gccatagtta atcgttttgt attctcaact
     2461 ccaaattctt tcccgccatt gctaaggatt cgtttctcat tctctatcga acgctttaaa
     2521 aaaatcaatc gaataaggaa tgttactaaa ataatcgcta ataccatatt agtatccttt
     2581 cttttatcta cacaaagaat aacacactta tgttaaccct atatgaactt taataaaaaa
     2641 ctaatctgtc tacaagctaa tcttaaattc cataccgtgt tcataaggga gaaaactata
     2701 atccatttga tagctttcta aaatattatt cacaatgtaa agacccaaac cggaactttc
     2761 atccttatct gtcacgattt gagaatgata gaatatatca aataaatgtt ctagttcttg
     2821 gtcacttaga ggcgcacatg tatttttgat agagagatag ccatcttgct cggatatgat
     2881 tacgcgccca tttttatctg aatatttaat tgcattacta atcaggtttg tcaaaacctt
     2941 atccaatgcc ctaagactca tgacgaccct ggtagcatct gtcaattgat tttcaattgt
     3001 aacacctatt gaatgagcta attcttgata acgtgataaa atatctacta aaactggctt
     3061 aacagtcaag gtctcacgac actctgtcca ctcttggaat ttagaagact ccagtacttc
     3121 ttccaataag tggctcatct ggtcaatctt atttatactc tttgcaatat attttggatg
     3181 atctttgtaa tctccaatat tatgctgcat attctctagg ataattctaa gactggctaa
     3241 aggggttttc aactcatgtg atgctccgcg gacaaaggaa accttttgat tttgcaattt
     3301 tacaatttgc tcattacgac tttccaactc atgaataacc ttcaacaagt gctcatacat
     3361 accattaatc tgttttccaa cttcaccaac ttcaccaact tcatctttcc tactttcatc
     3421 aaaacgaata ttgtcatcca aatcttgcat tttactagtc acttctgaaa tgtaaaaaag
     3481 aggattgagc aagcgtttag tataaaaata agaaaaaaca aaggaaaaag caattgtaac
     3541 caaaaatgta tatgggagat acaaaagcaa aatattcttt gcttctttgt agacatccac
     3601 cccgtgaaca aattgcactg ttacctgttt accatctgct gtactaacag acatatctaa
     3661 catcacgata taatttgata gctttccatc tttaatatcc aagtcatgca caagagggag
     3721 tcgcttatct acaatatctc ttttaaggtg agcagatatg gtcaaggact ttgaataaga
     3781 ctggagtaag cttggaattt catcagatgt cttagtcttt aaatactccg taaacactct
     3841 tgcgctctca ttaaactttt ccccctccag ttgaatataa taaaaaggaa aggtcaaata
     3901 aatagctata tgaatgacta gaccaacacc acctagaatt gcaaaacttc ttaaaaaaga
     3961 cttggttaat aatttaggat tttttatcat aagctaatct tatacccaac atttttcaca
     4021 gtcacgatac aatctaaagc taattttttg cgaagagtac gaatatagac atcaacgacc
     4081 ctatcacaag gtaaatcagc tacatctttt gaaatttctt ccaatatctg ctctctactt
     4141 aaaacttgat ttttatgctg aatcaaacac tttagtacca gtaattcctt tggtttgaga
     4201 tcaatttctt catttttata atgtgctttg taagaggtaa aatccactgt tacatcctga
     4261 tatcgccaaa gatcctctat gacgtagtaa cgtctgataa gcgccttaat acgcttgaca
     4321 agcagtacca aagaaaaagg ttttgtcaca tgatcatcag catagagatc aaatacctgt
     4381 gactgagtag tttcatctcc cagagcactc aagacgatga caggaatatc gtgcttttga
     4441 ttgatttctt ttaacacttc aaaaccactc ttcctaggca tcattaaatc cagtaccatg
     4501 agatggatag ggagatcttg aaatttttcc aagacctctt gtccatcctt agccataatg
     4561 acatgataac cctcttctgt cagaaatgct gcaattcctt ctctaatcat ttcctcgtca
     4621 tctgcaacta aaatgttcat ctctctccct ttctactacc agaactccat acatctattt
     4681 cctgtatgct atttgaaaat ttcctaccag cctatcatct atgataatgg aatggatttc
     4741 atttatccgc tactttttgt caacaacaac gtcaatacaa gaaaatcatt catcttgcag
     4801 cttatactct tcgaaaatct cttcaaacca cgtcagctct atctgcaacc tcaaaccagt
     4861 gttttgagca acctgcggct agctgcctag tttgctcttt gattttcatt gaatattagt
     4921 ttgatttttt aaataccagc tagaacggat ttgacatgca aaaaagaaac aggtctcttt
     4981 tgaaagaata aaaatttcag ataagactgc tctttttcta ctacacatgc tctaagacaa
     5041 atacgacgga gggtaataaa catatgaatt ttgtgttgaa tggtgaaaac cacgaatcgt
     5101 ttagaagcta taggttttag tttcatactc ttcgaaaatc tcttcaaacc acgtcagctc
     5161 tatctgcaac ctcaaaacag tgttttgagc aacctgcggc tagctgccta gtttgctctt
     5221 tgattttcat tgagtttcac tccactgtga cttatggtca gatgctgata cttttattct
     5281 tttatgcaat atcaaatttt aactggcctg ctttgacacc aatcttaagt gtgttgcctg
     5341 ccactaaatc tcccttaaga agaagttctg ccaacttgtc ctccacttct gtttgcaggg
     5401 ttctgcgaag tgggcgagct cccatctctg ggtcatatcc ttgatttgct aacaatttca
     5461 gagctgaagc ttgtaatttc aagtcaatgc ctttttcagc caaacttgcc actaaaggct
     5521 tgaccataat cttcaccact tcctgcatat ggtcactaga taggctatgg aagaccacct
     5581 tctcatcaat gcggttgatg aattccggtc tataagcttt tttcagttct tcaaacatgc
     5641 gtttttccat attttcctgg tcaaaacgaa tatccttagc cccaaaacca acagtcttat
     5701 catcacgaag ggcagtcgca cctagattcg atgtcataat gataatggta tttgaaaaat
     5761 cgaccttgcg tcccttgcta tctgtcaaga caccgtcatc cagaacctgc aagagaacat
     5821 taaagatatc tgggtgggcc ttctctacct catcaaagag gagaacggaa tagggtttat
     5881 tgcgaacctt ctctgtcagc tccccacctt cttcgtaacc cacatagcct ggaggagctc
     5941 catttagacg gctggctgcg aatttctcca tatactcact catatcaaag cggataaggg
     6001 ctgattcgtc atcaaagaga acttctgcca aagccttggc caactcggtc ttaccgacac
     6061 ctgtgggtcc taggaacata aaggaaccga tcggacgctt gtgactgcga attcctgact
     6121 gattacggcg aatggcacga ctaatgcttg aaacagcttg atcttgaccg atgacacgtt
     6181 tatggagttc tgcttcaaga tttaaatact tcttagcatc cgtttgagtc agtttttgaa
     6241 ctgggattcc tgacaagcga ctcaaggtgg tcaaaatatc agactctgtc accaagtctt
     6301 tgtagacagg tacttcctct tcttttgcga ttagctgggc tgcctgtttc cacttgccat
     6361 ccatcagggc cttgtcagct ggactcaaat ctgaatcgtc tgcttttaca tgctttgcct
     6421 tattttgcac tgttgctgct gcttcgtcca agaggtcgat agcagagtct ggcaagtgac
     6481 gactggttaa ataacgatga gccatcttaa ccgctgtttc aaccgcttca tctgtgattt
     6541 gtacacggtg atgtttctca taagtcgcct tcaaaccttg caaaatagtc atactatctg
     6601 ccacacttgg ttcttcaatc gtcactttag cgaaacgacg agaaagagcc gcatcttttt
     6661 cgatatgttt ttgatattct tcctgagtgg tggcaccaac cgttctcaaa gttccacgcg
     6721 ccaaggctgg tttcaagata ttggccgcat ccagagtcga atcaatcccg ctaccagaac
     6781 ccatgatggt gtggagttca tcgataaaga ggatgacttg gccatcttct tcaatatcct
     6841 tgatgatatt attcatgcgt tcttcaaagt caccacggaa gcgtgtccct gcaacgacat
     6901 tcatcaaatc aagttctaac acgcgcatct tagccatttc cgcaggcacg tcaccactag
     6961 caatacgctg ggcaagacca agggccagag ctgttttccc gacaccagca tccccaacca
     7021 agacagggtt gttcttagtc ttacggctca agatttgaat catacgtgag atttccttgt
     7081 cccgaccgat gactggttct aacttgccag aatgcgcttg ctctgtcaaa tcatgcgtat
     7141 agtcctcaag accaccacta ggagtctgcg gcatgcccat catattggcc atagaatttt
     7201 gcttgtcagc tactgtacga tggcgttggc gtaaagcctt gagatcttca cgagtccagc
     7261 ctgcccgttc ttctaaattt cgacgaaggg tagcaatctt gacctgatct ttcttgtctt
     7321 cataagaaaa accagccctc tccaagatac gagttgccaa ggcattgcca tcatgcaaaa
     7381 tcgcatagaa gacgtgctct gtccctagca ccttagcatg gaccactgac gctacatact
     7441 ctgcttcgtc aaaaagaacc tgcaaacgac gggagaacgg caattccgta aaggtttcat
     7501 cctggctata gtccgtttca gtcagttcca aagccacctc ttctaaacgg tccatctcat
     7561 acggataatc atttaaagtt gcccctgcta cactataact gtgattagac atggcaatca
     7621 acaagtgcca cgactctaga taacgagctc caaaatgtcc agcaaccatg taggcacttt
     7681 cgatacattc attcaatgct tttgaatagt tcatcttact tcccttttct atctacctct
     7741 tgtatgatct gacgtagcat gtttgctcga acaactggag cttcttctcc taaaacgcga
     7801 tccaaagcta ctgattctag caaattcatc tcctgcttgg tcatcaattc ctgctcaacc
     7861 aaaagctgga gaatatcctc ataaatttct tgactgactc gctcaccaat cgagtaaagc
     7921 agctcccgga gcatttcatg atgactagaa aactcaatcc gtcctatacg aatgtagcct
     7981 ccgccaccac gcttactttc aaccaagtag cctctacttt ccgtaaagcg tgtcttgatc
     8041 acgtagttaa tctgactagg aacaacctga aaggtatctg ccaactgact ccgttgcaac
     8101 tccacgatac cagattgatc taaaatcgcc ttgatgtagg cctcaatatg atccgatgta
     8161 tttttaaatc tcataacaaa cccacctctc tctttaaacc ttgaccttgt ttgactatta
     8221 taccgaaatt ttctcatttt taaaagaaaa agggcgctgg taaaggataa tcttcaccaa
     8281 ctccctattt ttctacttat ctaagcctaa ttctgccaag atttgacgtt tgtaggcaat
     8341 cttttggact tccttgtcct catcttcaga ccaatctagt ttaatttctg aaacaatctg
     8401 cccagggcga tttttcaaga tatagatgcg gtcgctgaga ttgagggcct cctcaatact
     8461 atgcgtgatg atcagagttg ttagctgcaa ctgtttgtga atctcaagat accaagcgtg
     8521 gagttccatc tttgtcatct catccaaggc gctaaaggcc tcatctaaga gaaagagctt
     8581 gtgcccaaaa aggtaggtcc ggagtaaggc tacacgctgg cgcatcccac cgctaagttc
     8641 atgaggatac ttgtctctta cagctgtcag ctggaaggtc gcaagaattt tatccgctcg
     8701 ggaaatagct tctgccttat ccaccttttg aatcaagagg ggcagaatga tatttccaag
     8761 caccgtcttg tgctccaaga gcagatcctt ttgcaacata taactcacgc gccccttggg
     8821 attttcttca ccatcaagga caattctccc tgactgaact tctaaaatcc cagcgattag
     8881 attaaagagg gtggtctttc caacaccact tgggcctagg atggaaacca cttcgcctga
     8941 agtcacctgt aggttgatat cctctaaaat cctctcctga ccataggcat aactgacgtg
     9001 ctctagtcta atttctgtca ttatttcaca aattcgttgg tgaagccttt gtctgtcaag
     9061 tcttctttaa ggataccatt ttctttatcc catttgtaga aagcattcca gcgagctgcg
     9121 tcaaattgac cccatttttc cttgtcgctt gcgtattctt ttgacaagta tttttgagat
     9181 tcgatgacaa agtcacgttt ttccttgagt tcaggtgcat tcttgatgag aatatctgca
     9241 gcttcttctg gatgttccat ggcatattgg tagccttttt tgatggcttg gatgactttg
     9301 cgagcttctt ctttgttatc tttcagatag tcgttgtttg cgatgataac tggtgaatag
     9361 tagtcaaact ccttgacata gtctttcaag tacatgaagt tagcatctac accttgagat
     9421 ttagcaagga taccatccca accgtagtaa atccaagcag tatcaaagac gccattggca
     9481 atcggtgtga ttgagtttga gtcgttattt ggtacttttt caaccttctc aaagtctcca
     9541 ccttgagatt ctaccaaggt tttcaacata gcaagttcag ttgggtcatt ccatgtccca
     9601 tatttcttac caaccaagtc ttttggactg cttacattat cagatttacg agagatgatt
     9661 cctgatgtat tgtgttcaac aatagctgca acggcagtga ttcctgctcc tttttccaat
     9721 ttcttagcca tgtagtcttg gaaatacact gcaaatggtg cctttccgtt gataaccaag
     9781 tcagaagaac tttcttctgg tggcaatttc aaatcaacat ccactccagc ttctttgaaa
     9841 taaccttttt ccttggcaac ataaagccct gtgtggttgg tatttggtgt ccagtctagg
     9901 ataaagtcaa ccttcttaag ttctgcctct ttgttgtctt tagaagcagt tccttgacca
     9961 caggccacaa gcacaacagc tacaagagct gttacaagcg ttaaaaacac tttccatgtt
    10021 ttcttcattt tgatttcctc ttttcttttt cagaaacatt ctaattctac gaacgtttcc
    10081 atttaatcac atatttttca ctgatatcga ccagcttcat acccaaaaga ctgataatcg
    10141 acaccagaat aataatggca aacatggtat catactgaaa cagtttttta gactgaatca
    10201 tataaacacc aagaccttca aaacctccca accactcaga taccacagtt gtgataaagg
    10261 cgtaggagac actgaccctc agacctgcat aaaagtaagg caggctaact gggattttaa
    10321 aatgccacag gatttgccaa ggcttggccc gcatcagact aaacaaggtc agcatatcct
    10381 tgtcgcaatg cctaaaaccg tccaaaatac taacgatgat gggaaaggtt gtcgttaaga
    10441 taatcaagac aatcttgggc aaaatcccat aacctagcca caagaccagg ataggagcta
    10501 tggcaatggt cggaatggtc tgaatgacca ccatcatagg gtaaatcagg tcattgagcc
    10561 aagtcaaact atccatgagc acagccataa gacaggcaat caaaactccc aaaatcagcc
    10621 ccagtaaagc cactctcaag gtcgcccagc tatggtgcca gagaaattct ctgtcacgaa
    10681 caaagggctg gagaatttca agaggtgtcg gcaggataaa cttggggaga agtttaagaa
    10741 aacctgctaa ctgccagatt aacaagactc cgagaaagcc caatagacta atgtgtcgtc
    10801 tcagtatact tctcaagttt ctcatcaata cttaaaatct ctcctacatt tattttgaca
    10861 ttggcaaaga cattgtctgc ctcctgccct gccacttcca gcgcttcttt tagaatgcgc
    10921 ataagctcat caaactcccc ttccaagacc gtttcaaatg gtgtcactac catcgtcact
    10981 tcttgagttt gcagataagc aatgacctga tcaataacag ctatccgatc aatcccctgt
    11041 gctaggggta aaacttgcaa ggcaatgctt gctttcataa gaacctcctc ttctcgtttt
    11101 cctttttaaa aaaagaaaaa cctttaccat acatggaaaa ggtgcaaaat tagactaagt
    11161 atcgttccct ccgctggcat tacccagatc aggtgcggtc gaagtttaac acttcctctc
    11221 agactgtaca cagactccca tatattatat gtatatatga tagcgcaaaa taaaaaaaat
    11281 gtcaaggaaa ctgcttacag aaaagagcag gaaatttctc ctactccaat tttctatact
    11341 cgttctccat cactgtttac tctgtagcca tccaccgtcg tattaacagc taaggcgcct
    11401 gaagagtaag aataatacca cttaccagag acctggtacc agcctgtttt cattgcccct
    11461 gaactaccca gataatacca cgagccattc tcctttaacc atcctgtctg catttcacca
    11521 gataatttca aataatacca gctagaacca tctttcagcc atcctgttga tttagaacca
    11581 tttgatttga aatgatacca actaccattt attttcttcc aaccgacagt tgaactatta
    11641 ttggatccat agctagagat atttcctgat tgattctgat aattttgtga agaagtcact
    11701 ccctctagct gtatatagcg acgacttccg ttataagccg tataactcaa ccacttgtag
    11761 ccgtcttttt caagtatctg atcataatga accttctccc caggataata gtaatcaatc
    11821 acagttccgc taactagggg ttcagttttg atagcagact tggtcttaaa ataatgagtt
    11881 ccacctgttg aagaaagaac agaattacct agaggatttt tattcacagc ctccaattga
    11941 acataacgat agcttccatt ataggcagta taactcaacc acttatagcc gtctttttca
    12001 agtatctgat cataatgaac cttctcccca ggataatagt aatcaatcac agttgcacta
    12061 actaggggtt cagttttgat agcagacttg gtcttaaaat aatgagttcc gcctgttgaa
    12121 gctgaggatt gactattccc aacactgccg ccatccaaat ctttaaaatg aataaatcct
    12181 gtcatcgtgt ttgcttttat aactcgttta ttataggatt ctgtataacc atagttatat
    12241 tcctcaatct caatctgatc tcccattaca tttgacaccc aggcaacatg accataagtt
    12301 cctgcagtag accaagtaat ggaaccaatc gtcggtgtat tatctacacg ataaccttcc
    12361 cgacgagcac gatgtcccca ttcattcgca tttccataag ctgccggaat ttcaaaacca
    12421 ttgacattac tcaaacgaaa ggctacaaaa gaagtacact gacgagaata catgcgccac
    12481 ttatcaatct cctggctccc atttttataa taagcaggat aatcatcccc acgcgcaatc
    12541 gatccatttc ctccggaata ggcatagaca ctatcaccag ctgctagcat caatcctact
    12601 actaaaaaag gaacaagctt tttaactgac atcttcaagt aataacttgt ccctcttgct
    12661 ataaacggta aaattttcat tcttcctcct tgaaaaataa tataaagcga tgattgcctt
    12721 cacctaaatt attcggagaa aaaagaaaaa gtgagaaaat ttctcacttt agtcaagata
    12781 atgaatcaaa ttcttttctg taagaatatc tgagtaagta aaggattcaa cgtaaacatt
    12841 aacttgttta tctccttcca catccccaaa ctccacaata aatagagatg gataaacttc
    12901 aattagctta cccaatctat ttttttggcg cttacgacca ttctccaaag tcatttctac
    12961 gacttgtccc tcatgtgcct tgatttcttc tttgattttt ttcatcttgg ctacatctgt
    13021 aaatgcatct gacatcttat gcctccctct ttgagatact tgaaaattta ttgtattctt
    13081 tttggaaaat caattccact gttccacgag ctccactacg gtttttctcg ataataactt
    13141 ccaccttatt atttgggata ccctcctctt cttcaccacc acgttcatag tagtcatcgc
    13201 gatagagaaa agctacgata tcagcgtcct gctcaataga cccagattca cgaatatcag
    13261 acaagaccgg tctcttgtcc tgacgttgtt ctacaccacg agaaagctga ctcagagcga
    13321 ttactggaac cttcaattcc ttggctagta ttttcaactg acgagaaatt tcagaaactt
    13381 cttgttgacg attttctcga ccagttcccg tgataagttg caaatagtct atcaaaatca
    13441 aaccaagatt tccagtttct tgagctaatt tacgagaacg agaacgaatc tctgtaatcc
    13501 gaatacctgg cgtatcatcg atatagatac tggcgttagc tagattaccc tgagcaatag
    13561 tatatttttg ccactcctca tctgtcaatt gccctgtacg gatagaatgt gactccacta
    13621 agccttctgc agctaacata cgatctacca agctttccgc acccatttcg agtgaaaaaa
    13681 tagcaaccgt tttgtccaac ttagtcccaa tattctgagc gatattcaag gcaaatgctg
    13741 tcttaccaac tgctggacga gctgctaaga taatcaactc ctcctcatga agtcctgttg
    13801 tcatatgatc caaatcacga taacctgtcg caatacctgt aatatcggtc gtttgttgcg
    13861 agcgagcttc cagatttcca aagttgagat tcaacacatc tcgaatgttc ttaaacccgc
    13921 ttcgatttgc attttcactg acatcaatca accctttttc tgcctgagca ataatttcat
    13981 cagctggttg tgacgcttcg taagcttggt tgacagactc tgtcaacttg acaattaaac
    14041 gacgtagcat tgctttttct gcaacaatct tagcataata ctccgcatta gcagaagttg
    14101 gcacagaatt aacaatctca accaagtaag acaagccacc aatattctgt aaatcacctt
    14161 gattatcaag gatagtacga accgttgttg catctatggc atcaccacga tcggataaat
    14221 cgaccatggc ttggaaaatc aaacgatggg catacttaaa aaagtcccga gactcaatgt
    14281 attctcgcac aaaaacaagt ttactctcat caataaagat agcccctaaa acggattgct
    14341 cagctaagat atcttgaggt tgtactcgta actcttctac ttctgccatc agacttccct
    14401 tcttttacaa tcttgtcaag aaagtgtaaa cttatccttc tttcacacga agattgatta
    14461 cacttgtgat atcttgatag attttcactg gcacatcaat caaaccaacc gctcgaatcg
    14521 gagcttgtac ttgaatatga cgtttatcaa tcttaattcc aaattgcttt tgcaattctt
    14581 ctgcaatctt cttattggta atagaaccaa aggtacgacc atctggacca actttttcaa
    14641 caaattctac aacagtttct tctgcttcaa gttgtgcttt aattgctttt ccttctgcaa
    14701 tcatctcagc gtgagctttt tcttccgatt tttgtttacc acgaagttca cctacagctt
    14761 gagcagtcgc ttctttggct agattctttt tgataagaaa gttttgcgca taccctgttg
    14821 gtacttcctt aatttcgcct tttttacctt ttcctttaac atctgctaaa aagattactt
    14881 tcattcttct ttctcctttt cctttatttc atttaataca atttctgtca gtttttcacc
    14941 tgcttctgac aaggttacat ctttaatttg agctgctgcc aaattaaagt ggcctccacc
    15001 gcctaactct tccataatcc gttgtacatt cagtttacta cgacttcgag ctgagataga
    15061 gataaatcct tgtgtattct tcgcaagaac aaaactcgct tcaatacctg acatggctaa
    15121 catggcatct gctgccttac taataacaac tgtatcatag catttcgtgt ccttagcctc
    15181 tgctattagt acatctgaac ctaatttaca cccctgtaaa ataagttcat tgacctcacg
    15241 atattcttca aaatctgtcg cagcgatttc ctggatagca atactatcac ttccgcgcgt
    15301 tctgagatag ctagcaacat caaatgtccg actagttact cgcgaggtga aatttttagt
    15361 atccaacatc ataccagcca tcaaaacact tgcttgcata cggctcaaac gatttttctt
    15421 agaattctgg aactgaatca attccgttac caactcactg gcactacttg caccactttc
    15481 gatataagta ataaccgcat tatctggaaa atcctgatcc cttctatggt ggtcaataac
    15541 aatggtttgg gtaaataaat cataaaattc ttttgataat gttaaggctg tctttgaatg
    15601 gtctacaaga atcaacaaag aacgattggt caccatcccc attgcatcct taacagacaa
    15661 caacttcgta actccttctt tttctatgaa tgaaacagct cgttcaatat ctggagacat
    15721 ttgttcttca tcataaagag catagctatt ttcaatcaca ttgctggcga acaactgcat
    15781 acctacagca gagcccaaag catccatgtc taaatttttg tgaccgacta caaaaacctg
    15841 atctacactc cgaatcttat ctgaaatagc tgtcatcata gcgcgcgtac gagtccgtgt
    15901 acgcttgatt gaagcagcag acccaccacc aaaataaact ggatttttcg tttcgtcgtt
    15961 ttccttaaca accacctggt cgccaccacg tacttcagcc aagttcaaat tgagcaaagc
    16021 aactttccct atctcatcat gatttccatc gccataagaa aatcccatac ttaaggtcaa
    16081 gggcaactgt ctctgtttcg actcttctct gaaagcatca ataacagaaa atttatcatt
    16141 catcaagccc tcaagcaccg tgtagtcagt aaatagataa aatcgatcca tacttacccg
    16201 acgagaaaac atcatgtatt tttctgaaaa ctctgatata aaattagcta caaaactatt
    16261 gatttgacta atatctgact cagaagttgc atcctccaaa tcatcataat tatccacaga
    16321 gacaatccca atcactggtc tacttgttac caattcatct gttatggctt gttccctgga
    16381 tacatctaca aaatacaaaa caccggaaga agcatccata tgaacagcat aacgcttctc
    16441 accaagcttg gcataagtag acggatttcc tactgaagcc ttgataatcg tttgaacagc
    16501 ttctaaatca aagtcaccat cttccttggt caaaatcaat tcagcatagg gattaaacca
    16561 ctcaacctct ccagaagata aattcaattt cataacacct acaggcattt gttccaatag
    16621 agatgtcaaa ctttcttccg cttggtggtt tacatactgt atctgttcta catcactcct
    16681 tgtataatgc actctcagtt tcttaaataa aaaaacatag cctcctacaa aaagaaacaa
    16741 aattaaaacc gtcaacagat tattattaac aaaaataatg aaagtggata agactccaaa
    16801 cgcaatcaat cctactagaa taggaaaaat tggacttaca taaaattttt tcattcaaaa
    16861 cctcttggca cccattatac cataataccc ctcaaaaagc gactttttaa aagtgtaatc
    16921 agtaattcta tcaattataa gaaaaaggta gtttacaatt cagtaaacct acctttacac
    16981 atattgaaat taagattctt taacctctaa caaaccaatt tcgccatcct cacgacgata
    17041 aatcacattg gttgtctgat cttcaacatc cacatagata aagaaatcat gccccaataa
    17101 atccatttgt agaattgctt cttccaaatc cattggtttt aaatcaattt gttttgaacg
    17161 aacaacttta gactggacaa catttgaatc ttccaccaaa gcatctgtaa ataattgacc
    17221 agttgctacc ttatttttat ttttacgctc gatttttgtt ttatttttac gaatctgacg
    17281 ttcaatttta tcagttacaa ggtcaattga accatacata tcttgagata catcttctgc
    17341 gcggagagta atagatccaa gcggaatcgt tacttccact ttagccgttt tttcacgata
    17401 aacttttaag ttaattcggg catccaactc ttgttctggt tggaagtact tttcgatctt
    17461 ttcgagttta gaaactacat aatcacgaat tgcttctgtt acttctaggt tttcaccacg
    17521 gatactatat ttaatcatat gagtaccttc tttctaaaca tttttgtttt tatgatttta
    17581 ttataacgct ttcattctat ttttgcaaat tttttcctca tcttacaagg gaaaatgttt
    17641 ttacatcctt agcaccagct tcttccaaca gtttcttaac acgatttata gttgctcctg
    17701 tagtatagat atcatctata agtaagattt ttttaggaat agtgactcca cttttaataa
    17761 agaaaggaag ttctgtcccc aagcgctctg aacgattttt agaagaactg gctctctctt
    17821 ctcttttctc taataaatct agatactcaa agcctgctgc ctctaccaag ccctcaacct
    17881 gattaaatcc tctgttagca tatctatcag gacttagggg aattacaaca aattgatact
    17941 ctttgtactt tttcaactcc tcacttaaaa atgaagcgaa aacttttctt aacaggaagt
    18001 ctccatcaaa cttataccga ctgaaaaaat ccttcatagc ttgattgtaa gtaaaaatcg
    18061 ctctatgact gacttcaact ccttctttac accaaagttg acaatcttga cactttgttg
    18121 acaactctgt tttcatacaa tttggacagt tctcttcccc aattctttca aaagtagaat
    18181 cacagtctga acaaagacaa gagtcatcat tcctcagaag taagagacta ctaaaagtta
    18241 aaacagtctt catagtctgc ccacataaca agcacttcat agaccagcct ccttattcat
    18301 catctgaatt tccttaatcg ccttcttgat tgaagcattt aacccatcat ggaagaaaag
    18361 caaatctcct gtcggtctat ccatgcttcg tccaactcgt ccaccaatct gaatcaaact
    18421 agacttggta aacaaacgat gattggcctc tactacgaaa acatccacac aagggaaggt
    18481 aactccacgc tccaagattg tcgtactgat aagtattgtc agttctccat ctcgaaaagc
    18541 ttgtacttgc tctaatcgat cctctgttac agaagataca aagccaattt tctcatttgg
    18601 aaattgctcc tgtaagattt ctgctaactg ctcccctttc ttaatttctg aagcaaaaat
    18661 gagtaacgga taagctgtct ttctctgctt ctcaatatag gactttaact ttggtgacaa
    18721 acgattcttg tctaagtagc gattaaaatc cgataaccaa attggttttg gaataatcaa
    18781 cggatttcca tgaaaccgtc tcggtaaatt cagtcttttt agttctccta aacggacctt
    18841 tttatctaac tcattggtcg aagtcgctgt taaaaagatt ctcaatccat tctcctttac
    18901 actattcttg acagcgtggt aaagcatggg attatcaaca taaggaaaag catctacttc
    18961 atccactatc agcaaatcaa aagcttgata aaacttcaat aactgatggg ttgttgcaac
    19021 aactagtggt gttcgaaaat aaggttccga ttctccatgt agcaaagcta ttccgcaaga
    19081 aaaatcctgt tgcaggcgct tgtacagctc caaacaaaca tctatgcgag gactagccaa
    19141 acacactgca ccacccgcat tgatcacttt agccactact tgataaatca tttctgtctt
    19201 tccagctcct gttaccgcat gaactaaggt tggcttttgc ttgtctactg cttgaagcaa
    19261 tccctctgac accttctctt gaaaaggagt taattggccg cgccatttga gaacatcttg
    19321 ctttggaaaa tcctcctgcg gaaaatagta taaagtttga tcacttctga ctcgcttcat
    19381 cagcaagcac tctcgacaat agtaagcacc gatgggcaaa taccattctt ctagaatagt
    19441 actattacaa cgttgacaga aaagtttccc cttctccttt ctcattgctg gaagtttctc
    19501 cgccaactga cgttcttctt ctgttaattc attctcagta aataaacgac cgagataatc
    19561 taaatttact ttcatacttc tttattcgta aaaactagca ctttagatga ttttttagta
    19621 caattaaatc atggaattta ggacaattaa agaggacggc caagtccaag aagaaatcaa
    19681 aaaatctcgc tttatctgcc atgccaagcg tgtttatagc gaagaagagg ctcgtgactt
    19741 cattactgcc atcaaaaaag aacactacaa agcgacacat aactgctctg cctttattat
    19801 tggagaacgt agtgaaatta aacgtacaag tgatgatggt gagcctagtg gtactgctgg
    19861 tgttcccatg cttggggtac tagaaaatca caatctcacc aatgtctgtg tggtcgtgac
    19921 acgctacttt ggtggtatta aactaggcgc tggaggacta attcgtgctt acgccggcag
    19981 tgtcgcctta gctgtcaaag aaattggtat tattgaaata aaagaacagg ctggcattgc
    20041 tattcaaatg tcttatgctc agtaccaaga gtacagtaac ttccttaaag aacatgatct
    20101 catggagctg gatacaaact ttacagatca agtcgatacg atgatttatg ttgataagga
    20161 agaaaaagaa actattaaag ctgcacttgt ggagtttttt aatggaaaag tcactttaac
    20221 tgaccaaggt ttacgagagg ttgaagttcc tgtaaactta gtgtaaacaa tgaataatac
    20281 agcgtttcgt tgacattctc acaactactt tagcgagcaa aataaaaaga tgcgtaccaa
    20341 aatatactag aaaatgaagc aattcaaacg aaacctgata tcgttttcct tcacacctat
    20401 ttactagaat tagctgaacg caatcacttg aaaattaatg actttgatct atgatatata
    20461 gaaatcctat cgcttcgata ggatttctat attttacaaa tggtatagat agcgttatac
    20521 taaagatatc ttatacaaag aggtattcat atgtctattt ataacaacat tactgaatta
    20581 atcggtcaaa caccgattgt taaacttaac aacatcgtgc cagaaggtgc tgcagacgtc
    20641 tatataaagc ttgaagcatt taatcctggt tcatctgtaa aagaccgtat tgcccttagc
    20701 atgattgaaa aagctgaaca agatggtatt ctgaaacctg gttctactat tgttgaagca
    20761 acaagtggaa acactggtat tggactttca tgggtaggtg ctgctaaagg gtataaagtc
    20821 gtcatcgtta tgcctgaaac tatgagtgta gaacgacgta aaattatcca agcttatggt
    20881 gctgaactcg tcctaactcc tggtagcgag ggaatgaaag gtgctattgc taaggctcaa
    20941 gaaatcgctg ctgaacgtga tggtttcctt cctcttcaat ttgacaatcc agctaatcca
    21001 gaagtacacg aaagaacaac aggagctgag atactagctg ctttcggtaa agatggatta
    21061 gatgcctttg ttgctggagt aggtaccggt ggaacgattt ctggtgtttc tcatgcactc
    21121 aaatcagaaa attctaacat tcaagtttat gcagtggaag ctgatgaatc tgctattcta
    21181 tctggtgaaa aacctggtcc tcacaaaatt caaggtatct cagctggatt tattcctgat
    21241 acacttgata ctaaagccta tgatggtatc gttcgtgtaa catcagatga tgctcttgca
    21301 ctcggacgtg aaattggtgg aaaagaaggc ttccttgtag ggatttcctc agctgcagct
    21361 atctacggag ccatcgaggt tgccaaaaaa ttaggtacag gtaaaaaagt ccttgctcta
    21421 gcaccagata acggtgaacg ttatctctct acagcactct atgaatttga agtttagtct
    21481 cctaaataca attggccctt attatagggc tttttatttt taccttgaaa ataggaagct
    21541 ctccctataa ggatcgactg catacaaaaa atg
//
LOCUS       DAVLXH010000035        21344 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00028199
            SAMN33607166-rid17955573.denovo.035, whole genome shotgun sequence.
ACCESSION   DAVLXH010000035 DAVLXH010000000
VERSION     DAVLXH010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607166
            Sequence Read Archive: SRR23725544
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21344)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21344)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721421.1
            Genome Coverage       :: 115x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:42:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,210
            CDSs (total)                      :: 2,161
            Genes (coding)                    :: 2,023
            CDSs (with protein)               :: 2,023
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 73 of 138
            Pseudo Genes (incomplete)         :: 60 of 138
            Pseudo Genes (internal stop)      :: 40 of 138
            Pseudo Genes (multiple problems)  :: 31 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21344
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607166-rid17955573.denovo.035"
                     /strain="AUSMDU00028199"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1349"
     gene            33..1210
                     /locus_tag="VYO11_001430"
                     /pseudo
     CDS             33..1210
                     /locus_tag="VYO11_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518194.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip family protein"
     gene            complement(1240..3792)
                     /locus_tag="VYO11_001431"
     CDS             complement(1240..3792)
                     /locus_tag="VYO11_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HEV1595979.1"
                     /translation="MKSFLKTYRTYFISFIIPVVIMSGVYLSQGIYWNSDNSPLLGDG
                     FHQYVIFDVALRNILHGNSSLFYTFTSGLGLNFYALSSYYLGSFLAPLVYFFDLTNMP
                     DAVYLTTLLKFGLIGLSTFFSLNKLFQSIPQTLKLALSTSYALMSFTVSQLEIKTWLD
                     VFILIPLIITGLHLLITEKKLLLYFTSLSILFIQNYYFGYMTVLFLIFWYLCQISWDF
                     KTRKSSVLDFIVISFLAGMASLIMTLPTLFDLQTHGEKLTEVTKFQTESSWYLDLFAK
                     QFIGSFDTTKYGAIPMIFVGLLPFILTILFFTLKSIKFHVKLIYVIFFAFLIASFYIE
                     ALDLFWQGMHTPNMFLHRYAWIFSTLLIYTAAEVLKRLKELKVWNFLVSLFLVVAGFL
                     ATIYLKSHYSFLTDLNILLTLEFLVVYSLLLLAVIKKFISVNLFAILISLFILVEMSL
                     NASSQMDGIAKEWGFASRSAYSRDIPAMESFSTYIGNQFTRTEKLQTQTGNDSMKFNY
                     NGISQFSSVRNRSSSSTLDKLGFKSSGTNLNLRYANNSILADSLFGIQYNISDSPIDK
                     YGFKDIYQKDNLTLYENQYSLPIAVASQSVYNDVKFNEHTLDNQASFLNQLANVNFDY
                     FSPISYEKTEKIENTNDLISVTSSSNEDAAIQYQIEVPENSQVYLSFINLHFSNDKQK
                     KVDILVNGEKKTFTTDNVFSFFNLGYTKEKKTFNINVSFPGNSQVSFESPTFYRLDTK
                     TFTEAIQKIKEQPVTVSTSKNKVFATYDVQQDTSIFFTIPYDKGWSAYQDGKKIEIKQ
                     AQTGFMKVDIPKGKGTITLSFIPNGFITGAICSFTSLLLFGIYNHRRKSSKA"
     gene            complement(3854..5476)
                     /locus_tag="VYO11_001432"
     CDS             complement(3854..5476)
                     /locus_tag="VYO11_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV1595980.1"
                     /translation="MLTVSDVSLRFSDRKLFDDVNIKFTEGNTYGLIGANGAGKSTFL
                     KILAGDIEPTTGHISLGPDERLSVLRQNHFDYEDERAIDVVIMGNEKLYSIMKEKDAI
                     YMKEDFSDEDGVRAAELEGEFAELGGWEAESEASQLLQNLNIPEELHYQNMSELANGE
                     KVKVLLAKALFGKPDVLLLDEPTNGLDIQSITWLEDFLIDFDNTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWKESSELAAKLLADRNAKAEEKIKQLQEFVARFSANA
                     SKSRQATSRKKMLDKIELEEIVPSSRKYPFINFKAEREIGNDLLTVENLTVKIDGETI
                     LDNISFILRPDDKTALIGQNDIQTTALIRAIMGDIDYEGTVKWGVTTSQSYLPKDNSA
                     DFAGGESILDWLRQFASKEDDDNTFLRGFLGRMLFSGDEVNKPVNVLSGGEKVRVMLS
                     KLMLLKSNVLVLDDPTNHLDLESISSLNDGLKNFKESIIFASHDHEFIQTLANHIIVL
                     SKNGVIDRIDETYDEFLENAEVQAKVKELWKD"
     gene            5682..6707
                     /gene="trpS"
                     /locus_tag="VYO11_001433"
     CDS             5682..6707
                     /gene="trpS"
                     /locus_tag="VYO11_001433"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HEV1595981.1"
                     /translation="MTKPIILTGDRPTGKLHIGHYVGSLKNRVLLQEEDKYDMFVFLA
                     DQQALTDHAKDPQTIVESIGNVALDYLAVGLDPNKSTIFIQSQIPELAELSMYYMNLV
                     SLARLERNPTVKTEISQKGFGESIPTGFLVYPIAQAADITAFKANYVPVGTDQKPMIE
                     QTREIVRSFNNAYNCDVLVEPEGIYPENERAGRLPGLDGNAKMSKSLNNGIYLADDAD
                     TLRKKVMSMYTDPDHIRVEDPGKIEGNMVFHYLDVFGRPEDAQEIADMKERYQRGGLG
                     DVKTKRYLLEILERELGPIRERRIEFAKDMGEVYNMIQKGSERAREVAGQTLSEVKGA
                     MGLHYFN"
     gene            6859..8337
                     /gene="guaB"
                     /locus_tag="VYO11_001434"
     CDS             6859..8337
                     /gene="guaB"
                     /locus_tag="VYO11_001434"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HEV1595982.1"
                     /translation="MSNWDTKFLKKGFTFDDVLLIPAESHVLPNDADLTTKLADNLTL
                     NIPIITAAMDTVTESQMAIAIARAGGLGVIHKNMSIAQQADEVRKVKRSENGVIIDPF
                     FLTPEHTIAEADELMGRYRISGVPVVETLENRKLVGILTNRDLRFISDYNQPISNHMT
                     SENLVTAPVGTDLATAESILQEHRIEKLPLVDEEGSLSGLITIKDIEKVIEFPNAAKD
                     EFGRLLVAGAVGVTSDTFERAEALFEAGADAIVIDTAHGHSAGVLRKIAEIRAHFPDR
                     TLIAGNIATAEGARALYEAGVDVVKVGIGPGSICTTRVIAGVGVPQVTAIYDAAAVAR
                     EYGKTIIADGGIKYSGDIVKALAAGGNAVMLGSMFAGTDEAPGETEIFQGRKFKTYRG
                     MGSIAAMKKGSSDRYFQGSVNEANKLVPEGIEGRVAYKGAAADIVFQMIGGIRSGMGY
                     CGAANLKELHDNAQFIEMSGAGLKESHPHDVQITNEAPNYSM"
     gene            complement(8388..9485)
                     /gene="recF"
                     /locus_tag="VYO11_001435"
     CDS             complement(8388..9485)
                     /gene="recF"
                     /locus_tag="VYO11_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000266665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HEV1595983.1"
                     /translation="MWLQHLSLKTFRNYKETKIDFNPKLNVFLGRNAQGKTNMLEAIY
                     FLALTRSHRTRTDKNLIHFDEEQLHLSGLVQKKTGSIPLEIELTQKGRVTKVNHLKQA
                     RLSDYVGHMNVVLFAPEDLQLIKGAPSIRRKFIDMELGQIKPIYLSDLTNYNHILKQR
                     NTYLKSAQKIDETFLSVLDDQLVDYGCRVMNHRLDFIKKLESFGRKKHFELSNQIEEL
                     SISYQSSVNITDKQNLSESFKIALEKSRSRDLFKKNTGVGPHRDDISFYINGMDASFG
                     SQGQHRSLVLSIKLAEIELMESITTESPILLLDDVMSELDNTRQLKLLETISQSIQTF
                     ITTTSLDHLQNLPENLSIFTIQDGKAAVNGN"
     gene            complement(9488..9856)
                     /gene="yaaA"
                     /locus_tag="VYO11_001436"
     CDS             complement(9488..9856)
                     /gene="yaaA"
                     /locus_tag="VYO11_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HEV1595984.1"
                     /translation="MEYKLFEEFITLQALLKELGITHSGGAIKSFLSEHSVYFNRELE
                     SRRGKKLRIGDKVDIPDMNIDILLTQPTSEEQDEYQADKVEKERIAKLVKKMNKGVKK
                     DKSKPASSPKSQQAPRFPGR"
     gene            10015..11265
                     /locus_tag="VYO11_001437"
     CDS             10015..11265
                     /locus_tag="VYO11_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEV1595985.1"
                     /translation="MELVHGISTHFIQSKKFKTNKITVRFTAPLSLDTIAGHMLSASM
                     LETANQMYPTSQDLRRHLASLYGTDMSTNCFRRGQSHIIELTFTYVRDEFLSRKNVLT
                     SQILELVKETLFSPVVVDNGFDPALFEIEKKQLLASLAADMDDSFYFAHKELDKLFFH
                     DERLQLEYSDLRNRILAETPQSSYSCFQEFLANDRIDFFFLGDFNEVEIQNVLESFGF
                     KGRKGDVKVQYCQPYSNILQEGMVRKNVGQSILELGYHYRSKYGDEQHLPMIVMNGLL
                     GGFAHSKLFTNVRENAGLAYTISSELDLFSGFLRMYAGINRENRNQARKMMNNQLLDL
                     KKGYFTEFELNQTKEMIRWSLLLSQDNQSSLIERAYQNALFGKSSADFKSWIAKLEQI
                     DKDAICRVANNVKLQAIYFMEGIE"
     gene            11262..12545
                     /locus_tag="VYO11_001438"
     CDS             11262..12545
                     /locus_tag="VYO11_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEV1595986.1"
                     /translation="MTKVVFEEKYYPAVKEKVYRTRLANGLTVALLPKKEFKEVYGSV
                     TVQFGSVDTFVTEVDGDVKQYPGGIAHFLEHKLFEREDSSDLMSAFTSIGADSNAFTS
                     FTKTNYLFSATDYFLENLDLLDELVTSAHFTEASILTEQDIIQQEREMYQDDPDSCLF
                     FSTLANLYPGTPLATDIVGSEESISQINLTNLQENFTKFYKPVNMSLFLVGNFDVERV
                     QDYFESKELKDSDFQEVAREKLFLQPVKLTDSMRMEVSSPKLAIGVRGKREVSEADCY
                     RHHILLKLLFAMMFGWTSDRFQKCYESGKIDASLSLEVEITSRFHFVMLTMDTKEPVA
                     LSHQFRKAIRNFTKDLDITEEHLDIIKREMFGEFFSSMNSLEFIATQYDAFENGETIF
                     DLPKILQEITLEDVLDAGHHLIDDGDIVDFTIFPS"
     gene            12587..13408
                     /locus_tag="VYO11_001439"
     CDS             12587..13408
                     /locus_tag="VYO11_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV1595987.1"
                     /translation="MRKKTIGEVLRLARINQGLSLDELQKKTEIQLDMLEAMEADDFD
                     QLPSPFYTRSFLKKYAWAVELDDQIVLDAYDSGSMITYEEVDVDEDELTGRRRSSKKK
                     KKKTSFLPLFYFILFALSILIFVTYYVWNYIQTQPEEPSLSNYSVVQSTSSTSSVPHS
                     SSSSSSSIESAISVSGEGNHVEIAYKTSKETVKLQLAVSDVTSWVSVSESELEGGVTL
                     SPKKKSAEATVATKSPVTITLGVVKGVDLTVDNQTVDLSKLTAQTGQITVTFTKN"
     gene            13419..13964
                     /gene="pgsA"
                     /locus_tag="VYO11_001440"
     CDS             13419..13964
                     /gene="pgsA"
                     /locus_tag="VYO11_001440"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HEV1595988.1"
                     /translation="MKKEQIPNLLTIGRILFIPIFIFILTIGNSIESHIVAAIIFAVA
                     SITDYLDGYLARKWNVVSNFGKFADPMADKLLVMSAFIVLIELGMAPAWIVAVIICRE
                     LAVTGLRLLLVETGGTILAAAMPGKIKTFSQMFAIIFLLLHWTLLGQVLLYVALFFTI
                     YSGYDYFKGSAYVFKGTFGSK"
     gene            13961..14788
                     /locus_tag="VYO11_001441"
     CDS             13961..14788
                     /locus_tag="VYO11_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HEV1595989.1"
                     /translation="MKSIIDVKNLSFRYKENQNYYDVKDITFHVKRGEWLSIVGHNGS
                     GKSTTVRLIDGLLEAESGEIVIDGQRLTEENVWNIRRKIGMVFQNPDNQFVGATVEDD
                     VAFGLENQGLSRQEMKKRVEEALALVGMLDFKKREPARLSGGQKQRVAIAGVVALRPA
                     ILILDEATSMLDPEGRRELIGTVKGIRKDYDMTVISITHDLEEVAMSDRVLVMKKGEI
                     ESTSSPRELFSRNDLDQIGLDDPFANQLKKSLSQNGYDLPENYLTESELEDKLWELL"
     gene            14773..15612
                     /locus_tag="VYO11_001442"
     CDS             14773..15612
                     /locus_tag="VYO11_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000510406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HEV1595990.1"
                     /translation="MGIALENVNFTYQEGTPLASAALSDVSLTIEDGSYTALIGHTGS
                     GKSTILQLLNGLLVPSQGSVRVFDTLITSTSKNKDIRQIRKQVGLVFQFAENQIFEET
                     VLKDVAFGPQNFGVSEEDAVKTAREKLALVGIDESLFDRSPFELSGGQMRRVAIAGIL
                     AMEPAILVLDEPTAGLDPLGRKELMTLFKKLHQSGMTIVLVTHLMDDVAEYANQVYVM
                     EKGRLVKGGKPSDVFQDVVFMEEVQLGVPKITAFCKRLADRGVSFKRLPIKIEEFKES
                     LNG"
     gene            15605..16399
                     /locus_tag="VYO11_001443"
     CDS             15605..16399
                     /locus_tag="VYO11_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000377903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEV1595991.1"
                     /translation="MDSMILGRYIPGDSIVHRLDPRSKLLAMMLLILIVFWANNPLTN
                     LILFIATGIFIALSGVSLSFFIQGLKSMFFLIAFTTIFQLFFISNGNVLFEFSFVRIT
                     DYALQQAGIIFCRFVLIIFFSTLLTLTTMPLSLASAVEALLAPLKRVKVPVHEIGLML
                     SMSLRFVPTLMDDTTRIMNAQKARGVDFGEGSIVQKVKAMIPILIPLFATSLKRADSL
                     AIAMEARGYQGGKGRSQYRQLKWTLKDTLTILVILVLGCCLFFLKS"
     gene            16458..17276
                     /gene="mreC"
                     /locus_tag="VYO11_001444"
     CDS             16458..17276
                     /gene="mreC"
                     /locus_tag="VYO11_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HEV1595992.1"
                     /translation="MNRFKKSKYVIIVFVTVLLVSALLATTYSSTIVTKLGDGISLVD
                     RVVQKPFQWFDSVKSDLAHLTRTYNENESLKKQLYQLEVKSNEVESLKTENEQLRQLL
                     DMKSKLQATKTLAADVIMRSPVSWKQELTLDAGRSKGASENMLAIANGGLIGSVSKVE
                     ENSTIVNLLTNTENADKISVKIQHGSTTIYGIIIGYDKENDVLKISQLNSNSDISAGD
                     KVTTGGLGNFNVADIPVGEVVATTHSTDYLTREVTVKLSADTHNVDVIELVGNS"
     gene            17276..17770
                     /gene="mreD"
                     /locus_tag="VYO11_001445"
     CDS             17276..17770
                     /gene="mreD"
                     /locus_tag="VYO11_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HEV1595993.1"
                     /translation="MRQLKRVGVFLLLPFFVLIDAHISQLLGSFFPHVHLASHFLFLF
                     LLFETIEVSEYLYLVYCFVIGLVYDVYFFHLIGITTLLFILLGAFLHKLNSVILLNRW
                     TRMLAMIVLTFLFEMGSYLLAFMVGLTVDSMSIFIVYSLVPTMILNFLWITVFQFIFE
                     KYYL"
     gene            17864..19042
                     /locus_tag="VYO11_001446"
     CDS             17864..19042
                     /locus_tag="VYO11_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEV1595994.1"
                     /translation="MKKKILASLLLSTVMVSQVAVLTTAHAETTDDKIAAQDNKISNL
                     TAQQQEAQKQVDQIQEQVSAIQAEQSNLQAENDRLQAESKKLEGEITELSKNIVSRNQ
                     SLEKQARSAQTNGAVTSYINTIVNSKSITEAISRVAAMSEIVSANNKMLEQQKADKKA
                     ISEKQVANNDAINTVIANQQKLADDAQALTTKQAELKAAELSLAAEKATAEGEKASLL
                     EQKAAAEAEARAAAVAEAAYKEKRASQQQSVLASANTNLTAQVQAVSESAAAPVRAKV
                     RPTYSTNASSYPIGECTWGVKTLAPWAGDYWGNGAQWATSAAAAGFRTGSTPQVGAIA
                     CWNDGGYGHVAVVTAVESTTRIQVSESNYAGNRTIGNHRGWFNPTTTSEGFVTYIYAD
                     "
     gene            19266..20045
                     /gene="rpsB"
                     /locus_tag="VYO11_001447"
     CDS             19266..20045
                     /gene="rpsB"
                     /locus_tag="VYO11_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HEV1595995.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIHVIDLQ
                     QTVKYADQAYDFMRDAAANDAVVLFVGTKKQAADAVAEEAVRSGQYFINHRWLGGTLT
                     NWGTIQKRIARLKEIKRMEEDGTFEVLPKKEVALLNKQRARLEKFLGGIEDMPRIPDV
                     MYVVDPHKEQIAVKEAKKLGIPVVAMVDTNTDPDDIDVIIPANDDAIRAVKLITAKLA
                     DAIIEGRQGEDAVAVEAEFAASETQADSIEEIVEVVEGDNA"
     gene            20124..21164
                     /locus_tag="VYO11_001448"
     CDS             20124..21164
                     /locus_tag="VYO11_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003053075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HEV1595996.1"
                     /translation="MAEITAKLVKELREKSGAGVMDAKKALVETDGDIEKAIELLREK
                     GMAKAAKKADRVAAEGLTGVYVNGNVAAVIEVNAETDFVAKNAQFVELVNTTAKVIAE
                     GKPANNEEALALIMPSGETLEAAYVSATATIGEKISFRRFALIEKTDAQHFGAYQHNG
                     GRIGVISVVEGGDEALAKQLSMHIAAMKPTVLSYKELDEQFVKDELAQLNHVIDQDNE
                     SRAMVNKPALPHLKYGSKAQLTDDVIAQAEADIKAELAAEGKPEKIWDKIIPGKMDRF
                     MLDNTKVDQAYTLLAQVYIMDDSKTVEAYLESVNASVVEFARFEVGEGIEKAANDFEA
                     EVAATMAAALNN"
BASE COUNT         6807 a         3400 c         4398 g         6739 t
ORIGIN      
        1 gtataatcta ttatatcaaa attttagaca atatgtttaa aaaaggagaa actaagttta
       61 aagaatggaa agcaatttta aaaaaaacca acctttatta ttgtcatgat cgggatttct
      121 cttattccag atctgtacaa tatcatattt ttgtcatcaa tgtgggatcc atatgggcaa
      181 ttgtctgact tacctgtggc agttgtaaat aatgataaag aggcttccta taatggtaat
      241 actatggcaa taggaaaaga catggtgtcc aatttaaaag aaaataaaac cttggatttt
      301 cattttgtag atgaagagga aggaaagaag ggattggaag atggcgatta ctatatggta
      361 gtgactttac caagtgattt atctgaaaaa acaactacat tatccaatat tcaatcgaca
      421 gcagcttatc aatcattgac aagtgagcaa caaactgaga taagtgattc tgtatctcaa
      481 aatttaactg ctagtattca atcggctcag tcaattgtag ctttagtaca agatttacag
      541 ggaagtttag aaaacttaca aaatcaatct tctaatcttt cgactttaaa aaatcaatct
      601 aatcaagtat cacctattac ttctacttct ttgataggat tgtcaagtgg attaacagag
      661 atacaaggag atgttactag caaattagtt cctgccagtc agtcgattgc atcaggtgta
      721 aacgcatata ctacaggtgt tgataaagtt tctcaggacg tcatccagag agccgttggg
      781 cttggttgaa atctcgagct gaaataaatg gtattatagc tgttttggca ggaattttgg
      841 tatatggagg agttcatctt attggtttaa ctgctaatca tgagatgaga atatttattc
      901 tcatcatcct aacaagttta gtattcatgt ctatggtgac cactttaaca acgtggaata
      961 gccgtatagg agctttcttc tcacttattt tgcttttact acagttagca tcaagtgcag
     1021 gtacttatcc acttgctttg acaaatgatt tctttagatc tattaatccc tggttaccaa
     1081 tgagctattc agtttcggga ttacgacaaa caatctccat caacaagtca ttttcctagc
     1141 tgtcatacta gctctattta ctggtttagg tatgctagcc tatcaacata agaaaatgga
     1201 agaagattaa aaaaatcgac cgattaactg gtcgattttt tatgccttag atgactttcg
     1261 tctgtgatta tagattccaa atagtaagag agaagtaaag gaacagattg ctccagtaat
     1321 aaaaccattg ggaatgaagg aaagtgtaat agttcctttc cccttgggaa tgtcaacttt
     1381 cataaatcca gtttgagctt gtttaatttc tattttctta ccatcttggt aggcagacca
     1441 acctttgtca taaggaatgg tgaagaaaat agatgtatct tgttggacat catatgtagc
     1501 aaaaaccttg tttttagaag ttgatactgt gacaggttgt tctttaattt tttgaattgc
     1561 ctcggtgaaa gttttggtat ctaaacgata gaaggtagga gattcaaatg atacttgtga
     1621 atttccaggg aaactaacat tgatattgaa agtttttttc tctttagtat atcctagatt
     1681 aaagaaggag aagacattat cagttgtaaa agtctttttt tcaccattta caaggatgtc
     1741 aaccttcttt tgtttatcgt tagaaaagtg aaggtttatg aaagagagat aaacttggct
     1801 gttttctgga acttcaattt gatactggat tgctgcatct tcatttgaag aacttgtgac
     1861 actaatcaaa tcattagtat tttctatttt ttctgttttt tcataagata ttggagaaaa
     1921 ataatcaaaa ttgacgttag caagttgatt taaaaatgag gcctgattat ccaaggtatg
     1981 ttcattgaac ttgacatcat tgtaaacaga ttgactagca actgcaatcg gaagagagta
     2041 ttgattttca tatagggtaa gattatcttt ttgatagata tctttaaaac catacttatc
     2101 aataggactg tctgagatat tgtactggat accaaataaa ctatcagcca aaatactatt
     2161 atttgcatat cggagattga gattagtccc agaggattta aaaccaagtt tatctaaagt
     2221 agagcttgat gaacgatttc gaacagatga aaattgagag attccattgt agttgaattt
     2281 catactgtca tttcctgtct gagtttgtag tttttcagta cgagtaaatt gatttccaat
     2341 atatgttgag aaagattcca tagctgggat atctcgacta taagcacttc gagaagcaaa
     2401 tccccattcc ttagcaattc cgtccatttg agatgaagca tttaaactca tttcaaccag
     2461 tataaataaa gagattagaa tggcaaatag attcacagat ataaactttt tgataactgc
     2521 aaggagtaaa agagaataga caaccaaaaa ttcaagagta agcagaatat tcaaatctgt
     2581 taaaaaagaa taatgcgatt ttagatagat ggtagctaaa aatcctgcta ctacaagaaa
     2641 aagcgaaact aaaaaattcc agactttaag ttctttcaga cgctttaaga cttctgctgc
     2701 tgtgtaaatt aacaaggtag agaaaatcca agcatagcga tgtaaaaaca tgtttggagt
     2761 atgcatgcct tgccaaaata agtcaagagc ttctatgtaa aagcttgcaa ttagaaatgc
     2821 aaagaatatt acatatatga gtttcacgtg aaacttaata gatttcagcg taaaaaataa
     2881 aatggtcaaa ataaagggaa gtagtccaac aaaaatcatt gggatggccc catactttgt
     2941 tgtgtcaaag gaaccaatga attgcttagc aaagagatca agataccagc tactttcagt
     3001 ttgaaacttt gtaacttcag tcaatttttc cccatgtgtc tgtaaatcaa atagagtggg
     3061 aagagtcata atcaaactag ccataccagc taaaaaggag ataactatga aatcaagaac
     3121 agatgatttt cgagtcttaa agtcccacga aatttgacag agataccaga aaataagaaa
     3181 caatactgtc atatatccaa aataataatt ttgaataaat aagattgaca gacttgtaaa
     3241 gtacaatagg agtttctttt cagttatcag tagatgtaaa ccagttataa ttaaaggaat
     3301 caagataaaa acatctagcc aggtttttat ctctaattga ctgacagtga aactcatcag
     3361 agcataggaa gtagataagg ctagttttaa agtctgaggg atagattgaa acaatttatt
     3421 caaactaaaa aaggttgaca gaccaatcaa tccaaatttt aagagagtgg tcagatagac
     3481 agcatctggc atattcgtta gatcaaaaaa gtaaactaga ggcgcgagaa aactacccaa
     3541 gtaataacta gatagggcat agaagtttag ccctagacca cttgtaaagg tgtaaaacag
     3601 actactattt ccatgtagga tatttcgtaa ggctacatca aaaataacgt attgatgaaa
     3661 gccatctcct aatagaggag agttgtcgct attccagtag ataccttgag atagatatac
     3721 tccagacata atcactacag gaatgatgaa agaaataaaa taggttcgat atgtttttaa
     3781 aaatgatttc atgttacctc gtagaatgat agaaaactca gttggttaac ccaactgagt
     3841 tttgaagttt tatttagtct ttccaaagtt ctttaacttt tgcttgtact tctgcatttt
     3901 ctaggaattc atcgtaggtt tcatcgatac ggtcaatgac gccattttta gataagacaa
     3961 tgatatggtt agccaaagtt tgaataaact cgtggtcatg gctggcaaag atgattgatt
     4021 ctttaaagtt tttcaatcca tcattcaagc ttgagataga ttccaagtcc aagtgatttg
     4081 ttggatcatc aagtacaagg acatttgatt ttaagagcat gagttttgaa agcatgacac
     4141 gaactttttc tccccctgac aagacattta caggtttgtt aacttcatct ccagagaaga
     4201 gcatacggcc gaggaaacca cgtaggaaag tattgtcatc atcttcttta cttgcgaatt
     4261 gacgcaacca gtcaagaatt gattctcctc ctgcaaaatc agctgagtta tcttttggta
     4321 ggtaagattg actagttgta actccccact tgacagttcc ttcatagtca atatctccca
     4381 tgattgcacg aattaatgca gtcgtttgaa tatcattttg tccaataagt gctgtcttat
     4441 catctggacg caagatgaaa ctaatattat ccaagatagt ttcaccatca atctttacag
     4501 ttagattttc tactgtcaag agatcattac caatctcacg ttccgcttta aagttgataa
     4561 atggatattt acgactagat ggtacaatct cttctagctc aatcttatca agcattttct
     4621 tacgtgatgt tgcctgcctt gacttagaag cattggcaga gaaacgagca acgaattctt
     4681 gcaattgttt aattttttct tctgctttag cattacggtc tgctagcaat ttagcagcaa
     4741 gctcagaaga ttccttccag aagtcgtagt ttccgacata gagtttgatt tttccaaagt
     4801 caaggtcggc catgtgagta caaactttgt ttaagaagtg acggtcgtgg gatactacga
     4861 taactgtgtt atcaaagtca atcaagaagt cttctaacca agtaatcgat tggatatcca
     4921 aaccgttagt aggctcgtcc aagagaagaa catctggttt accaaaaagt gctttggcga
     4981 ggagaacctt tactttttca ccgttggcca attcgctcat gttttggtag tgtaattctt
     5041 ctggaatgtt taggttttga agtagttgag aggcttcact ctctgcttcc caacctccaa
     5101 gttcggcaaa ctctccttcg agttcggcag cacgaacccc gtcctcgtct gagaaatctt
     5161 ccttcatgta gatagcatct ttctctttca tgatgctata aagtttttca tttcccatga
     5221 taacgacatc aatggcacgt tcatcttcgt agtcaaagtg attttgacga agaacagaga
     5281 gacgttcatc tggaccaaga gagatgtgac cagtagtagg ttcgatatct ccagctaaaa
     5341 tttttaaaaa ggttgatttt ccggcaccat tagcaccgat taatccgtaa gtatttcctt
     5401 ctgtaaattt gatattgaca tcatcaaaaa gtttgcgatc actaaaacgt agtgaaacat
     5461 cagatactgt aagcaatgtt tttctcctat atgtgtaata tatttattct actagaaaat
     5521 acagaaatat tcaaattttt atttgtcaat tttgtgtaaa ttatatttac agtatccttt
     5581 acacaaatct gtaaaaagca aggctgattt attttgataa attacggtta tttcattaaa
     5641 aaaatgctat aattgaaagg actatatcga aggagaacaa aatgactaaa cccattattt
     5701 taacaggaga ccgtccaaca ggaaaattgc atattggaca ttatgttgga agtctcaaaa
     5761 atcgagtatt attacaggaa gaggataagt atgatatgtt tgtgttcttg gctgaccaac
     5821 aagccttgac agatcatgcc aaagatcctc aaaccattgt agagtctatc ggaaatgtgg
     5881 ctttggatta tcttgcagtt ggattggatc caaataagtc aactattttt attcaaagcc
     5941 agattccaga gttggctgag ttgtctatgt attatatgaa tctagtttcg ttagcacgtt
     6001 tggagcgaaa tccaacagtc aagacagaga tttctcagaa aggatttgga gaaagcattc
     6061 cgacaggatt cttggtctat ccaatcgctc aagcagctga tatcacagct ttcaaggcta
     6121 attatgttcc tgttgggaca gatcagaaac caatgattga gcaaactcgt gaaattgttc
     6181 gttcttttaa caatgcatat aactgtgatg tcttggtaga gccggaaggt atttatccag
     6241 aaaatgagag agcagggcgt ttgcctggtt tagatggaaa tgctaaaatg tctaaatcac
     6301 taaataatgg tatttattta gctgatgatg cggatacttt gcgtaaaaaa gtaatgagta
     6361 tgtatacaga tccagatcat atccgcgttg aggatccagg taagattgag ggaaatatgg
     6421 ttttccatta tctagatgtt tttggtcgtc cagaagatgc tcaagaaatt gctgatatga
     6481 aagaacgtta tcaacgaggt ggtcttggtg atgtgaagac caagcgttat ctacttgaaa
     6541 tattagaacg tgaactgggt cctattcgtg agcgccgtat tgaatttgct aaggatatgg
     6601 gagaagttta taatatgatt caaaaaggta gtgaaagagc gcgtgaagtt gcgggtcaaa
     6661 ccctatctga ggtaaaaggg gcaatgggac ttcattactt taactaagtt tattttacaa
     6721 gaaactatca tttctatctc gaagaaaaga tagtttttta tttacccctg taacatttga
     6781 caaattttta tagaatggta tgatagatac aatataaaaa gagtcaagct caaaaagaaa
     6841 gaaaagagga aacttcgaat gtctaattgg gacactaaat ttttgaaaaa aggttttacc
     6901 tttgatgatg tattgcttat tccagctgaa agtcatgtgt tgcctaacga tgcagattta
     6961 acaactaaat tggcagataa tttgacttta aatatcccaa ttattaccgc tgccatggac
     7021 acagttacag agagtcaaat ggccattgct attgctcgtg caggtggtct cggagttatc
     7081 cataaaaaca tgtcaattgc tcaacaagca gacgaggttc gtaaggtaaa acgttctgaa
     7141 aatggagtta ttattgatcc gttcttcttg acgcctgaac atacaattgc tgaagcagat
     7201 gagcttatgg gtcgttaccg catcagtggt gttccagttg ttgaaacact tgaaaatcgt
     7261 aaattggttg gtattttgac aaaccgagat cttcgtttta tttcagatta taatcaacca
     7321 atttcaaacc atatgactag tgaaaatctt gttactgctc ctgtgggtac ggatcttgca
     7381 acggctgaga gtattcttca agagcatcgt attgaaaaac ttccgttggt cgatgaagaa
     7441 ggcagtcttt ctggtttgat cactatcaaa gatattgaaa aagttattga gtttccaaat
     7501 gcggctaaag atgagtttgg tcgtcttcta gttgcaggtg cagtaggtgt tacttcagat
     7561 acatttgaac gtgcagaggc tctttttgag gcaggagcgg atgcgattgt tattgatact
     7621 gcacatggtc attctgcagg tgtcttgcgt aaaattgccg agattcgtgc tcatttccca
     7681 gatcggactt tgattgctgg aaatattgct actgctgaag gtgcacgtgc cctttatgaa
     7741 gcgggtgtag acgttgttaa ggttggtatt ggaccaggtt ctatctgtac tactcgtgtg
     7801 attgctggtg ttggtgttcc gcaagtaaca gctatctacg atgctgcagc tgttgcgcgc
     7861 gaatatggta aaacgattat tgctgacggt gggatcaagt attctggaga tattgtaaaa
     7921 gcacttgctg caggtggaaa tgctgttatg cttggatcta tgtttgctgg aactgatgaa
     7981 gctccaggcg aaactgaaat cttccaagga cgtaaattca agacttaccg tggtatggga
     8041 tcaattgctg ctatgaagaa aggttcaagc gaccgttatt tccaaggttc tgtcaatgaa
     8101 gcaaacaagc tcgttccaga aggaattgaa ggtcgtgttg cttataaagg agcggcagct
     8161 gatattgttt tccaaatgat tggtggtatt cgctctggta tgggttactg tggtgcagct
     8221 aaccttaaag aactacacga taatgctcaa tttattgaaa tgtctggtgc tggtttgaaa
     8281 gaaagccatc ctcatgatgt gcaaattact aatgaggcac caaattattc tatgtaaaaa
     8341 acaatgaaaa gaactccagt gaaaacagga gttcttttac aatgttgtca atttccattt
     8401 acagcagctt taccatcctg aatagtgaag atacttagat tttctggcag attttgaaga
     8461 tggtctaagc ttgttgttgt gataaaggtt tggattgatt gagaaatcgt ttctaataat
     8521 tttaactgtc tagtgttgtc aagttcactc atcacatcgt caagcagtaa tatcggagat
     8581 tctgtggtaa tgctttccat taattcgatt tctgctaatt ttatcgagag gacgagacta
     8641 cgatgttgac cttggcttcc gaaactagca tccatcccat ttatataaaa agaaatgtca
     8701 tctcgatgag gaccgacacc agtattcttt ttaaataaat ctctggatct acttttttct
     8761 aaagcaattt tgaaagattc ggataagttt tgtttgtcag ttatattgac agaagattga
     8821 taggatattg acaactcttc gatctgatta gagagttcaa aatgtttctt acgcccaaat
     8881 gattctagtt tttttatgaa atctaagcgg tgattcatta cacgacatcc ataatcaact
     8941 agctgatcat ctaacacaga aaggaatgtt tcatctattt tttgagctga ttttaggtaa
     9001 gtgtttcttt gctttaggat gtggttataa ttggttaagt cagataaata gattggctta
     9061 atttgcccaa gttccatatc aatgaatttt cgtcgaatcg aaggtgctcc tttaattagt
     9121 tgtaaatctt caggagcaaa taagacaaca ttcatgtgtc ctacataatc tgaaaggcgt
     9181 gcctgtttta agtgattaac ttttgttaca cggccttttt gtgttagttc gatttctagg
     9241 ggaatggatc cagttttttt ctgaacgaga cctgaaagat gaagttgttc ctcatcaaaa
     9301 tgaatgagat ttttatctgt tcgagttcga tgactacgcg ttaaggctaa aaaatagata
     9361 gcctctaaca tgtttgtttt tccttgtgca ttacgtccca aaaagacatt caatttagga
     9421 ttaaagtcta ttttcgtttc tttgtaatta cgaaaagtct tgagagatag atgttgtagc
     9481 cacatgatta tctaccaggg aatcgtggag cttgttggct tttaggtgat gaagcaggtt
     9541 tcgatttgtc ttttttaact cccttattca tctttttgac aagtttagcg atccgttctt
     9601 tttcaacttt atcagcttgg tattcatctt gttcttcaga agtaggttgt gtcaacaaga
     9661 tgtcaatgtt catgtcaggg atgtcaactt tatcgccaat acgaagtttt tttccacgac
     9721 gactctctaa ttccctatta aagtaaacag aatgttcaga gagaaatgat ttaatagctc
     9781 ctccgctatg tgtaattcca agttctttga gtagtgcttg gagggtaata aattcttcaa
     9841 ataatttgta ttccataatt cacctcaatc tttggtatta taccatattt tcctaaaaat
     9901 agtgagagag acagcgagaa atgtaagcga tttttatttc aaaagtgtta cagggaacaa
     9961 gaaaatttca ggttttcgtg atataataga agtctgtata taaggaggta aatcatggag
    10021 ttagtgcatg gaatttcaac acattttatc caatcaaaaa agtttaaaac aaacaaaatt
    10081 accgtgcgtt ttaccgctcc attatccctt gatacgattg caggtcacat gttgagtgca
    10141 agtatgctag agactgctaa tcagatgtac cccacttctc aagatttgag gagacacttg
    10201 gccagtctat acggtacaga tatgtcaacc aattgtttca gaagagggca aagccacatt
    10261 atagaattga catttaccta tgttcgtgat gagtttttaa gtaggaaaaa cgtgctaacc
    10321 tctcagattt tggaacttgt aaaagaaact cttttttcac ccgtagtagt tgataatggg
    10381 tttgatccgg ccttatttga aattgagaaa aaacaattgc tagcaagttt agcagctgat
    10441 atggatgatt ctttttattt tgcacataaa gaattggata aattgttttt tcatgatgaa
    10501 cgtcttcaat tggaatatag tgatttacga aatcgtattt tagctgaaac tccacaaagt
    10561 tcttattctt gtttccaaga atttttagcc aatgatcgaa tagatttctt tttcctaggt
    10621 gattttaatg aggttgaaat tcaaaatgta ttagaatcat ttggctttaa aggtcgaaaa
    10681 ggagatgtga aggttcagta ttgtcaacct tattctaata tccttcagga aggtatggtt
    10741 cggaaaaatg tgggacaatc cattttggaa ttaggttatc attaccgttc taaatatggt
    10801 gatgaacaac atttacccat gattgtaatg aatggtttac ttggtggatt tgctcactct
    10861 aagctcttta caaatgtccg tgaaaatgct ggattagctt ataccatttc aagtgagctt
    10921 gatttattta gtggattctt gaggatgtat gctggtatca atcgagaaaa tcgtaaccag
    10981 gctcgtaaaa tgatgaataa tcaactgctt gatttaaaaa aaggttattt tacagagttt
    11041 gagttaaatc agaccaagga aatgattcgt tggtcgttgt tactttctca agataatcaa
    11101 tcttcattga ttgaacgtgc ttatcaaaat gccttatttg gaaaatcttc agcagacttt
    11161 aaaagttgga ttgcaaagct tgaacaaatt gacaaagatg ctatttgtag agtagctaat
    11221 aatgtgaaac tacaagcgat ttactttatg gaaggaatag aatgacaaag gttgtttttg
    11281 aagaaaaata ctatccagct gtaaaagaaa aggtttatcg aactcgtttg gccaacggat
    11341 tgacagttgc tcttttgcct aaaaaggaat ttaaagaggt ttacgggagt gtcactgtac
    11401 agtttggttc ggtagatacg tttgtcacag aagttgacgg agatgtaaaa caatatcctg
    11461 gaggaattgc tcattttctt gaacataaat tatttgagag agaagattct agtgatttga
    11521 tgtcggcttt tacgagtata ggtgcagata gtaatgcctt tacaagcttt acaaaaacaa
    11581 actatctttt ttcagcaacg gattattttt tagaaaattt agatttactt gatgaattgg
    11641 taacatcagc acactttact gaagcttcca ttctgacaga gcaggatatt attcagcaag
    11701 aacgagaaat gtaccaagat gatccagatt cgtgtttatt cttttcaact ttagcgaatt
    11761 tgtatcctgg tacaccttta gcaactgata tagttggaag tgaggagtcc atttcccaaa
    11821 tcaatctaac taatttgcaa gaaaatttta caaagtttta caaacctgta aacatgtctc
    11881 tgtttttagt tggtaatttt gatgtggagc gagtacagga ctattttgaa agcaaagaac
    11941 tgaaagattc agattttcag gaagtagcaa gagaaaagtt gtttttacag cctgtaaagc
    12001 taacagatag tatgagaatg gaagtatctt ctcccaaact agcgattgga gttagaggta
    12061 agcgagaagt ttctgaagcg gattgctatc gacatcatat tttattaaaa ttattgtttg
    12121 caatgatgtt tggttggact tcggatcgtt ttcaaaaatg ttatgaatca ggtaaaattg
    12181 atgcgtcctt atctctggaa gttgaaataa caagtcgctt tcattttgtc atgttgacaa
    12241 tggatacgaa agagccagtt gctttgtctc atcaatttag gaaggctatt cgtaatttta
    12301 caaaggattt agatattaca gaggaacatt tagatattat caaaagagag atgtttggcg
    12361 aatttttcag tagcatgaac tctcttgaat ttattgcaac gcaatatgat gcttttgaaa
    12421 atggtgagac aatttttgat ttgccgaaaa ttttacagga aattacttta gaggatgtcc
    12481 ttgatgctgg acatcattta atagatgatg gtgacatagt tgattttaca atatttccat
    12541 cgtagtaacc tatcataata gacactagaa agaagggatg acaagtatga gaaaaaaaac
    12601 aattggagag gttttacgat tagctagaat caatcaggga ttgagtttag atgaattgca
    12661 gaaaaagaca gaaatccagt tagatatgtt ggaagcaatg gaagcagacg atttcgatca
    12721 acttccaagt cctttttaca cgcgttcttt cttgaaaaaa tatgcatggg ctgttgagtt
    12781 agatgaccaa attgttttgg atgcttatga ttctgggagt atgattactt atgaggaagt
    12841 agatgttgat gaagatgagt tgacaggtcg tagacgttca agtaagaaaa agaagaaaaa
    12901 aacatcattt ttacctttat tttattttat cctttttgct ttatcgattt taatttttgt
    12961 gacttattat gtttggaact atattcaaac tcaaccagag gagccttctc tttctaatta
    13021 cagtgtggtt caatcaacaa gttcaactag ctctgttccc cactcctcaa gtagtagttc
    13081 ttctagtata gaatcagcta taagtgtatc aggcgaagga aatcatgtag aaatcgctta
    13141 taagacaagt aaggaaacag ttaaattgca attggcagtt tcagatgtta caagttgggt
    13201 cagtgtttca gaaagcgaac ttgagggcgg tgtaacctta tcgccaaaga agaaaagtgc
    13261 agaagcaaca gttgcaacta aaagtcctgt aacaattacg ttaggtgttg taaaaggtgt
    13321 tgatttgaca gtagataatc agactgttga tttatcgaaa ttaacagctc agactggaca
    13381 aatcactgta acctttacta aaaattaagg aaaaacgaat gaaaaaagaa caaattccca
    13441 atctcttaac aataggtcga attctcttta tacctatttt tatctttatt ttaacgatag
    13501 gaaattcgat agagagtcat atagttgcag ctattatctt tgctgttgcc agtattaccg
    13561 actatttaga tggatattta gctcgtaaat ggaatgtggt cagtaatttt ggtaaatttg
    13621 cagatcctat ggcggataag ttactagtta tgtcggcttt tattgtgttg attgagttag
    13681 gtatggctcc ggcttggatt gttgcagtga ttatctgtcg tgagttagct gtgacaggtt
    13741 taaggctttt attggttgaa actggtggaa caattttagc agcagcaatg cctggaaaaa
    13801 ttaaaacttt tagtcagatg tttgccatta ttttcttgct attacattgg actttgcttg
    13861 gtcaagttct actttatgta gccttatttt tcactatcta ctctggctat gactatttca
    13921 agggtagtgc ctatgtattt aaagggacat ttggttcgaa atgaaatcaa taattgatgt
    13981 aaaaaatctt tcttttcgct ataaagaaaa tcagaactac tacgatgtga aggatattac
    14041 gtttcacgtg aaacgtggag aatggctttc gattgtaggg cataatggta gtggtaaatc
    14101 aacgacggtt cgattaattg atggcttact ggaagcagaa tccggagaga ttgtaattga
    14161 tggccaacgt ttgactgagg aaaatgtttg gaatatacgt cgtaaaatcg gtatggtttt
    14221 tcaaaatcca gacaatcaat ttgttggagc gactgttgaa gatgatgttg cttttggttt
    14281 ggaaaatcag ggactttctc gtcaagaaat gaaaaagaga gtggaagaag ctctggcttt
    14341 agttggcatg ttggacttta aaaagagaga gccagcgcgt ctatcaggtg gtcaaaagca
    14401 acgtgtggcc attgcaggtg ttgtagccct aagaccagct attttaatct tagatgaagc
    14461 aacgagtatg ttggatcctg aggggcgtag agaacttatt gggacagtaa aaggaattcg
    14521 aaaagactat gatatgacgg tcatttctat tacccatgat ttggaagaag tcgccatgag
    14581 tgatcgcgta ttggtcatga aaaaagggga aattgaatca actagtagtc caagggagct
    14641 tttctctcga aatgatttag atcaaattgg attagacgat ccttttgcta atcaattaaa
    14701 aaaatctttg agccagaatg gctatgattt acctgaaaat tatttgacag aaagtgagct
    14761 agaggataag ctatgggaat tgctctagaa aatgtgaatt ttacatatca agaaggtact
    14821 cccttagctt cagcagcttt gtcggatgtt tctttgacga ttgaagatgg ctcttataca
    14881 gctttaattg ggcacacagg tagtggtaaa tcaactattt tacaactctt aaatggttta
    14941 ttggtgccaa gtcaagggag tgtgagggtt tttgatacct taatcacctc gacttctaaa
    15001 aataaagata ttcgtcaaat tagaaaacag gttggcttgg tatttcagtt tgctgaaaat
    15061 cagatttttg aagaaacggt tttgaaggac gttgcttttg gaccgcaaaa ttttggagtt
    15121 tctgaagaag atgctgtgaa gactgcgcgt gagaaactgg ctctggttgg aattgatgaa
    15181 tcactttttg atcgtagtcc gtttgagctg tcagggggac aaatgagacg tgttgccatt
    15241 gcaggcatac ttgccatgga gccagctata ttagtcttag atgagccaac agctggtcta
    15301 gatcctctag ggagaaaaga gttgatgacc ctgttcaaaa aactccacca gtcagggatg
    15361 accatcgtct tggtaacgca tttgatggat gatgttgctg aatatgcaaa tcaagtctat
    15421 gtaatggaaa agggacgttt agtaaagggg ggcaaaccaa gtgatgtctt tcaagacgtt
    15481 gtttttatgg aagaagttca gttgggagta cctaaaatta cggccttttg taaacgattg
    15541 gctgatagag gcgtgtcatt taaacgatta ccgattaaga tagaggagtt caaggagtcg
    15601 ctaaatggat agtatgattt tggggcgtta tatcccaggg gattcgattg ttcaccgatt
    15661 ggatccacgt agcaaattgc ttgctatgat gctactgatt ttgattgtgt tttgggctaa
    15721 taaccccttg acgaatctga ttctttttat agcgacaggg atatttattg ccttgtcagg
    15781 agtatctctt tcatttttta ttcagggctt gaagtctatg tttttcttga ttgccttcac
    15841 aactattttt caactatttt tcatttctaa tgggaatgtt ttatttgagt tttcgtttgt
    15901 gagaatcacg gattatgctt tgcaacaagc tgggattatt ttttgtcgct ttgtattgat
    15961 tattttcttt tcaactttgt taaccttaac aaccatgcct ttaagtttgg catcagctgt
    16021 cgaagcttta ttagcacctt taaagcgtgt gaaagttcca gttcatgaaa ttggattgat
    16081 gctgtctatg agtttgcgtt ttgtcccaac cttgatggat gatacgactc ggattatgaa
    16141 tgcacagaaa gctcgtggag tggattttgg agaaggaagc atcgttcaaa aagtaaaggc
    16201 gatgattccc attttgattc ctctttttgc gacaagttta aaacgtgcag attccttggc
    16261 tatcgctatg gaagcgcgtg gctatcaggg tggaaaaggc agaagtcaat accgacaatt
    16321 gaaatggact ctaaaggata cgctgaccat tcttgttatt ctcgtacttg gttgttgttt
    16381 atttttctta aaatcttagt agctttcagg aattgataaa aagttactgt aacagttttt
    16441 gatataaagg tagggatatg aaccgtttta aaaaatcaaa atatgtcatt attgtttttg
    16501 tcactgttct gcttgtgtca gctctcttag cgacgactta ttcaagtaca attgtgacaa
    16561 aattaggaga tggaatctca ttggttgata gagttgtaca aaaacctttt cagtggtttg
    16621 attctgtcaa atcagatttg gctcatttga cacgaacata taatgaaaat gaaagtttga
    16681 agaaacagct ttaccaatta gaagttaaat caaatgaggt ggaaagttta aagacagaaa
    16741 atgaacaact gcgccaattg cttgatatga agtctaaatt gcaagccaca aagactttag
    16801 cagcagatgt tattatgcgt tctccggtat cttggaagca ggagttgacc ttagatgcag
    16861 gtagatcaaa aggtgcttct gagaacatgt tagctattgc aaatggtggc ttgattggga
    16921 gtgtttcaaa agtagaggag aactctacta tagtcaacct tctgacaaat acggaaaatg
    16981 ctgataagat ttctgttaaa attcaacatg gctctactac aatttatgga attattattg
    17041 gctatgacaa ggaaaatgac gttcttaaaa ttagccaatt aaatagtaat agcgatatta
    17101 gtgcgggaga taaggtgact actggtggat taggaaactt taacgttgct gatattcctg
    17161 ttggtgaagt ggttgccaca acgcatagta cagactattt gacacgagaa gtaactgtta
    17221 aattgagtgc agatactcat aatgtagatg tgatagaatt agtggggaat tcataatgag
    17281 acagttgaag cgagttggag tatttttatt gcttcctttc tttgttctaa ttgacgccca
    17341 tattagccag cttctgggct catttttccc ccatgtacat ttggctagtc attttctttt
    17401 tctatttctc ttatttgaga cgatagaagt atcagagtat ctctacctag tctattgttt
    17461 tgttataggc ttggtttatg atgtttactt tttccatcta atagggatta caactctctt
    17521 atttatctta ttgggagcct tccttcataa attgaatagt gttattttgt tgaatcgttg
    17581 gacaagaatg ctagctatga ttgtgctgac attcctgttt gaaatgggta gttatctttt
    17641 ggcttttatg gtagggttga cagtagatag catgtcgatt tttatagtct atagcttggt
    17701 accgacgatg attttaaatt ttttatggat tactgttttt caatttattt ttgaaaaata
    17761 ttatctataa gaacgacata taaatgtaac aaaggcgtaa tatttattag gccttttttt
    17821 ggtatactag tattgtcttt aaaagaagga gtatctacgt aatatgaaga aaaaaatctt
    17881 agcgtcactt ttattaagta cagtaatggt ttctcaagta gctgttttaa caactgcgca
    17941 tgcagaaacg actgatgaca aaattgctgc tcaagataat aaaattagta acttaacagc
    18001 acaacaacaa gaagcccaaa aacaagttga ccaaattcag gagcaagtat cagctattca
    18061 agctgagcag tctaacttgc aagctgaaaa tgatagatta caagcagaat ctaagaaact
    18121 cgagggtgag attacagaac tttctaaaaa cattgtttct cgtaaccaat cgttggaaaa
    18181 acaagctcgt agtgctcaaa caaatggagc cgtaactagc tatatcaata ccattgtaaa
    18241 ctcaaaatca attacagaag ctatttcacg tgttgctgca atgagtgaaa tcgtatctgc
    18301 aaacaacaaa atgttagaac aacaaaaggc agataaaaaa gctatttctg aaaaacaagt
    18361 agcaaataat gatgctatca atactgtaat tgctaatcaa caaaaattgg ctgatgatgc
    18421 tcaagcattg actacgaaac aggcagaact aaaagctgct gaattaagtc ttgctgctga
    18481 gaaagcgaca gctgaagggg aaaaagcaag tctattagag caaaaagcag cagctgaggc
    18541 agaggctcgt gcagctgcgg tagcagaagc agcttataaa gaaaaacgag ctagccaaca
    18601 acaatcagta cttgcttcag caaacactaa cttaacagct caagtgcaag cagtatctga
    18661 atctgcagca gcacctgtcc gtgcaaaagt tcgtccaaca tacagtacaa acgcttcaag
    18721 ttatccaatt ggagaatgta catggggagt aaaaacattg gcaccttggg ctggagacta
    18781 ctggggtaat ggagcacagt gggctacaag tgcagcagca gcaggtttcc gtacaggttc
    18841 aacacctcaa gttggagcaa ttgcatgttg gaatgatggt ggatatggtc acgtagcggt
    18901 tgttacagct gttgaatcaa caacacgtat ccaagtatca gaatcaaatt atgcaggtaa
    18961 tcgtacaatt ggaaatcacc gtggatggtt caatccaaca acaacttctg aaggttttgt
    19021 tacatatatt tatgcagatt aatttacaga gggactcgaa tagagccctc ttttcaggtt
    19081 ttaccgtgac aatccctatt aaaaattata tcaaaatagc ttgaaaatat tggaaaagta
    19141 tggtagaatg aaaattgtcg tgtgaacgat aatactcatt cttgatgaat tgtgaagcag
    19201 ttgcccttgg gtcgttttgc gagttgaagt caagaagagg aaaaaaacaa aaaggagaaa
    19261 tactcatggc agtaatttca atgaaacaac ttcttgaggc tggtgtacac tttggtcacc
    19321 aaactcgtcg ctggaatcct aagatggcta agtacatctt tactgaacgt aacggaatcc
    19381 acgttatcga cttgcaacaa actgtaaaat acgctgacca agcatacgac ttcatgcgtg
    19441 atgcagcagc taacgatgca gttgtattgt tcgttggtac taagaaacaa gcagctgatg
    19501 cagttgctga agaagcagta cgttcaggtc aatacttcat caaccaccgt tggttgggtg
    19561 gaactcttac aaactgggga acaatccaaa aacgtatcgc tcgtttgaaa gaaattaaac
    19621 gtatggaaga agatggaact ttcgaagttc ttcctaagaa agaagttgca cttcttaaca
    19681 aacaacgtgc gcgtcttgaa aaattcttgg gcggtatcga agatatgcct cgtatcccag
    19741 atgtgatgta cgtagttgac ccacataaag agcaaatcgc tgttaaagaa gctaaaaaat
    19801 tgggaatccc agttgtagcg atggttgaca ccaatactga tccagatgat atcgatgtaa
    19861 tcatcccagc taacgatgac gctatccgtg ctgttaaatt gatcacagct aaattggctg
    19921 acgctattat cgaaggacgt caaggtgagg atgcagtagc agttgaagca gaatttgcag
    19981 cttcagaaac tcaagcagat tcaattgaag aaatcgttga agttgtagaa ggtgacaacg
    20041 cttaatttat acaaatagta attacctagg agggcggggc ttagcccggc tctcctattt
    20101 tcaaaaaata taggagaatt aaaatggcag aaattacagc taaacttgta aaagagttgc
    20161 gtgaaaaatc tggtgccggt gttatggacg ctaaaaaagc gcttgtagaa acagacggtg
    20221 acatcgaaaa agcgattgaa ttgcttcgtg aaaaaggtat ggctaaggca gctaagaaag
    20281 ctgaccgtgt tgctgcagaa ggtttgactg gtgtttatgt taacggtaat gttgcagcag
    20341 ttattgaagt aaacgctgaa actgacttcg ttgcaaaaaa cgctcaattc gttgaattgg
    20401 taaatactac agctaaagtc attgctgaag gaaaacctgc taacaatgaa gaagctcttg
    20461 ctttgataat gccttcaggt gaaactcttg aagctgcata cgtatctgca acagcaacta
    20521 tcggagagaa aatctcattc cgtcgctttg cattgattga aaaaacagac gcacaacact
    20581 ttggagcata ccaacataac ggtggacgta tcggtgttat ttcagttgtt gaaggtggag
    20641 acgaagcact tgctaaacaa ttgtcaatgc acatcgcagc gatgaaacca acagttcttt
    20701 cttacaaaga attggatgag caattcgtta aagatgagtt ggcacaattg aatcacgtta
    20761 tcgaccaaga caacgaaagc cgtgcaatgg ttaataaacc agctcttcca cacttgaagt
    20821 atggatcaaa agctcaatta actgatgatg ttattgctca agctgaagct gacatcaaag
    20881 ctgaattggc tgcagaaggc aaaccagaaa aaatctggga caaaattatt ccaggtaaaa
    20941 tggatcgctt catgcttgat aacactaaag ttgaccaagc ttacacactt cttgcacaag
    21001 tttacatcat ggatgacagc aagacagttg aagcatacct tgaatcagtt aacgcttcgg
    21061 tagttgagtt tgctcgcttt gaagttggtg aaggtatcga gaaagctgca aacgacttcg
    21121 aagctgaagt tgcagctaca atggcagcag ccttgaataa ctaataatag aaaggaagca
    21181 atttgcttcc ttttttggac tctttgtcaa ctgtagtggg ttgaaaaaaa gctaagctcg
    21241 agaaaggaca aatttcgtcc tttctttttt gatattcagg gcgataaaaa tccgtttttt
    21301 gaagttttca aagttccgaa aaccaaaggc attgcgcttg ataa
//
LOCUS       DAVLXH010000036        20729 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00028199
            SAMN33607166-rid17955573.denovo.036, whole genome shotgun sequence.
ACCESSION   DAVLXH010000036 DAVLXH010000000
VERSION     DAVLXH010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607166
            Sequence Read Archive: SRR23725544
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20729)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20729)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721421.1
            Genome Coverage       :: 115x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:42:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,210
            CDSs (total)                      :: 2,161
            Genes (coding)                    :: 2,023
            CDSs (with protein)               :: 2,023
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 73 of 138
            Pseudo Genes (incomplete)         :: 60 of 138
            Pseudo Genes (internal stop)      :: 40 of 138
            Pseudo Genes (multiple problems)  :: 31 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20729
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607166-rid17955573.denovo.036"
                     /strain="AUSMDU00028199"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1349"
     gene            complement(585..2312)
                     /gene="ezrA"
                     /locus_tag="VYO11_001449"
     CDS             complement(585..2312)
                     /gene="ezrA"
                     /locus_tag="VYO11_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HEV1595997.1"
                     /translation="MSNGQLIYLMVAIAVILVLAYVVAIFLRKRNEGRLEALEERKEE
                     LYNLPVNDEVEAVKNMHLIGQSQVAFREWNQKWVDLSLNSFADIENNLFEAEGYNHSF
                     RFLKASHQIDQIESQITLIEEDIAAIRNALADLEKQESKNSGRVLHALDLFEELQHRV
                     AENSEQYGQALDEIEKQLENIQSEFSQFVTLNSSGDPVEAAVILDNTENHILALSHIV
                     DRVPALVTTLSTELPDQLQDLEAGYRKLIDANYHFVETDIEARFHLLYEAFKKNQENI
                     RQLELDNAEYENGQAQEEINALYDIFTREIAAQKVVENLLATLPTYLQHMKENNTLLG
                     EDIARLNKTYLLPETAASHVRRIQTELESFEAAIVEVTSNQEEPTQAYSVLEENLEDL
                     QTQLKDIEDEQISVSERLTQIEKDDINARQKANVYVNRLHTIKRYMEKRNLPGIPQTF
                     LKLFFTASNNTEDLMVELEQKMINIESVTRVLEIATNDMEALETETYNIVQYATLTEQ
                     LLQYSNRYRSFDERIQEAFNEALDIFEKEFDYHASFDKISQALEVAEPGVTNRFVTSY
                     EKTRETIRF"
     gene            complement(2394..4340)
                     /gene="gyrB"
                     /locus_tag="VYO11_001450"
     CDS             complement(2394..4340)
                     /gene="gyrB"
                     /locus_tag="VYO11_001450"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002283665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HEV1595998.1"
                     /translation="MTEEIKNLQAQDYDASQIQVLEGLEAVRMRPGMYIGSTSKEGLH
                     HLVWEIVDNSIDEALAGFASHIQVFIEPDDSITVVDDGRGIPVDIQEKTGRPAVETVF
                     TVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVHVHKNGKIHYQEYRRGHVVAD
                     LEVVGDTDRTGTTVHFTPDPEIFTETTIFDFDKLNKRIQELAFLNRGLQISITDKRQG
                     LEQTKHYHYEGGIASYVEYINENKDVIFDTPIYTDGEMDDITVEVAMQYTTGYHENVM
                     SFANNIHTHEGGTHEQGFRTALTRVINDYARKNKLLKDNEDNLTGEDVREGLTAVISV
                     KHPNPQFEGQTKTKLGNSEVVKITNRLFSEAFSDFLMENPQIAKRIVEKGILAAKARV
                     AAKRAREVTRKKSGLEISNLPGKLADCSSNNPAETELFIVEGDSAGGSAKSGRNREFQ
                     AILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGAEFDVSKARYQKLVLMTDAD
                     VDGAHIRTLLLTLIYRYMKPILEAGYVYIAQPPIYGVKVGSEIKEYIQPGADQEIKLQ
                     EALARYSEGRTKPTIQRYKGLGEMDDHQLWETTMDPEHRLMARVSVDDAAEADKIFDM
                     LMGDRVEPRREFIEENAVYSTLDV"
     gene            complement(4355..4918)
                     /locus_tag="VYO11_001451"
     CDS             complement(4355..4918)
                     /locus_tag="VYO11_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEV1595999.1"
                     /translation="MKYHDYIWDLGGTLLDNYETSTAAFVETLALYGITQDHDSVYQA
                     LKVSTPFAIETFAPNLENFLEKYKENEARELEHPILFEGVSDLLEVISNQGGRHFLVS
                     HRNDQVLEILEKTSIAAYFTEVVTSSSGFKRKPNPESMLYLREKYQISSGLVIGDRPI
                     DIEAGQAAGLDTHLFTSIVNLRQVLDI"
     gene            complement(5003..5557)
                     /locus_tag="VYO11_001452"
     CDS             complement(5003..5557)
                     /locus_tag="VYO11_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DJ-1/PfpI family protein"
                     /protein_id="HEV1596000.1"
                     /translation="MVKVAVMLAQGFEEIEALTVVDVLRRANITCDMVGFEEQVTGSH
                     AIQVRADHVFDGDLSDYDMIVLPGGMPGSAHLRDNQTLIQELQSFEQEGKKLAAICAA
                     PIALNQAEILKNKRYTCYDGVQEQILDGHYVKETVVVDGQLTTSRGPSTALAFAYELV
                     EQLGGDAESLRTGMLYQDVFGKNQ"
     gene            complement(5568..6791)
                     /locus_tag="VYO11_001453"
     CDS             complement(5568..6791)
                     /locus_tag="VYO11_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HEV1596001.1"
                     /translation="MKRSLDSRVDYSLLLPVFFLLVIGVVAIYIAVSHDYPNNILPIL
                     GQQVAWIALGLVIGFVVMLFNTEFLWKVTPFLYILGLGLMILPIVFYNPSLVASTGAK
                     NWVSINGITLFQPSEFMKISYILMLARVIVQFTKKHKEWRRTVPLDFLLIFWMILFTI
                     PVLVLLALQSDLGTALVFVAIFSGIVLLSGVSWKIIIPVFVTAVTGVAGFLAIFISKD
                     GRAFLHQIGMPTYQINRILAWLNPFEFAQTTTYQQAQGQIAIGSGGLFGQGFNASNLL
                     IPVRESDMIFTVIAEDFGFIGSVLVIALYLMLIYRMLKITLKSNNQFYTYISTGLIMM
                     LLFHIFENIGAVTGLLPLTGIPLPFISQGGSAIISNLIGVGLLLSMSYQTNLAEEKSG
                     KVPFKRKKVVLKQIK"
     gene            complement(6828..9278)
                     /locus_tag="VYO11_001454"
     CDS             complement(6828..9278)
                     /locus_tag="VYO11_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DnaQ family
                     exonuclease/ATP-dependent helicase"
                     /protein_id="HEV1596002.1"
                     /translation="MKTIGNRYVVVDLEATSTGSKAKIIQVGIVVIEDGEIVDHYTTD
                     VNPHEPLDAHIKELTGLTDQRLAQAPDFSQVARKIFDLVEDGIFVAHNVQFDANLLAE
                     NLFFEGYELRNPRVDTVELAQVFFPELEKYSLPILCRELGIPLKHAHTALSDAQATAE
                     LLLFLREKMTQLPKGLLERLLEMADALLYESYLVIEETYRNQSILSSPDLVQVQGLYF
                     KKMAASLEPRKLSQDFSKNISLLNLEVREEQESFAKEVGLLLKDEPVSLIQAPTGIGK
                     TYGYLLPALSQSKERQIVLSVPTKILQNQIMEEEGKRLKEVFHTDIHSLKGPQNYLKL
                     DAFYHSLQENDENRLFRRFKMQVLVWLTETETGDLDEIGQLYRYQHFLADLRHDGNLS
                     SQNLFVTEDFWKRSQERAETCKLLVTNHAYLVTRLEDNPEFVSDRLLIIDEVQKILLA
                     LENLLQETYDIQSIIDLIDKALVGEENRVQQRILESIRFECLYLIEQFQSGKSRKNIL
                     DSLDNLHQYFSELEVEGFDELVRYFTAEGDYWLEVTETSQKKIQISSTKSGRTLLSSL
                     LPESCQVLGVSATLEISQRVSLADLLGYPEVKFVKIESRGKQEQEVVMVKDFPLVTET
                     SLEVYAREVAALLVEIQAFQQPILVLFTAKDMLLAVSDLLTVSHLAQYKNGDVHQLKK
                     RFEKGEQQILLGAASFWEGVDFSSHPFVIQVVPRLPFQNPQEPLTKKINQELNQEGKN
                     AFYDYQLPMAIIRLKQALGRSMRREYQRSLTLILDRRIVGKRYGKQIVASLAEEATVK
                     TISRSEVDEAIDRFFNEL"
     gene            complement(9478..10407)
                     /locus_tag="VYO11_001455"
     CDS             complement(9478..10407)
                     /locus_tag="VYO11_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006154193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEV1596003.1"
                     /translation="MEKIVITATAESIEQVEQLLEAGVDRIYVGEKDFGLRLPTTFSY
                     DQLREIAKLVHDAGKELLVAVNALMHQDMMDRIKPFLDFLEEIKTDYITIGDAGVFYV
                     VNRDGYSFKTIYDASTMVTSSRQINFWGQKAGASEAVLAREIPSAELFKMPEILEIPA
                     EVLVYGASVIHHSKRPLLQNYYNFTHIDDEKTHKRDLFLAEPSDPESHYSIFEDNHGT
                     HIFANNDLDLMIKLTELVEHGFTRWKLEGLYTPGQNFVEIAKLFIQARSLIQEGNFSH
                     DQAFLLDEEVRKLHPKNRFLDTGFYDYDPDMVK"
     gene            10547..10834
                     /locus_tag="VYO11_001456"
     CDS             10547..10834
                     /locus_tag="VYO11_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3270 domain-containing protein"
                     /protein_id="HEV1596004.1"
                     /translation="MPVRKLQSYEVDYQEELNQQLPHYQAYTPEAQSDANLKEILFFI
                     NIAVFCICIAIFSFIFLALKLSTALAFAAAIGFSLLVLKVQRSIIKRKRRR"
     gene            complement(10868..12202)
                     /gene="ciaH"
                     /locus_tag="VYO11_001457"
     CDS             complement(10868..12202)
                     /gene="ciaH"
                     /locus_tag="VYO11_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000491790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     CiaH"
                     /protein_id="HEV1596005.1"
                     /translation="MFSKLKKTWYADDFSYFIRNFGVFTLIFSTMTLIILQVMHSSLY
                     TSVDDKLHGLSENPQAVIQLAINRATEEIKDLENARADASKVEIKPNVSSNTEVILFD
                     KDFTQLLSGNRFLGLDKIKLEKKELGHIYQIQVFNSYGQEEIYRVILMETNISSVSTN
                     IKYAAVLINTSQLEQASQKHEQLIVVVMASFWILSLLASLYLARVSVRPLLESMQKQQ
                     SFVENASHELRTPLAVLQNRLETLFRKPEATIMDVSESIASSLEEVRNMRFLTTSLLN
                     LARRDDGIKPELAEVPTSFFNTTFTNYEMIASENNRVFRFENRIHRTIVTDQLLLKQL
                     MTILFDNAVKYTEEDGEIDFLISATDRNLYLLVSDNGIGISTEDKKKIFDRFYRVDKA
                     RTRQKGGFGLGLSLAKQIVDALKGTVTVKDNKPKGTIFEVKIAIQTPSKKKK"
     gene            complement(12192..12866)
                     /gene="ciaR"
                     /locus_tag="VYO11_001458"
     CDS             complement(12192..12866)
                     /gene="ciaR"
                     /locus_tag="VYO11_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator CiaR"
                     /protein_id="HEV1596006.1"
                     /translation="MIKILLVEDDLGLSNSVFDFLDDFADVMQVFDGEEGLYEAESGV
                     YDLILLDLMLPEKNGFQVLKELREKGITTPVLIMTAKESLDDKGHGFELGADDYLTKP
                     FYLEELKMRIQALLKRSGKFNENTLTYGNIVVNLSTNTVKVEDTPVELLGKEFDLLVY
                     FLQNQNVILPKTQIFDRLWGFDSDTTISVVEVYVSKVRKKLKGTTFAENLQTLRSVGY
                     LLKDVQ"
     gene            complement(12975..15521)
                     /locus_tag="VYO11_001459"
     CDS             complement(12975..15521)
                     /locus_tag="VYO11_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001149089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M1 family metallopeptidase"
                     /protein_id="HEV1596007.1"
                     /translation="MQAVEHFIKQFVPEHYDLFLDLSRETKTFSGKVTITGQAQSDRI
                     SLHQKDLEITSVEVAGQARPFTVDHDNEALHIELAEAGQVELVLAFSGKITDNMTGIY
                     PSYYTVDGVKKEVLSTQFESHFAREAFPCVDEPEAKATFDLSLRFDQAEGELALSNMP
                     EIDVENRKETGIWKFETTPRMSSYLLAFVAGDLQGVTAKTKNGTLVGVYSTKAHPLSN
                     LDFSLDIAVRSIEFYEDYYGVKYPIPQSLHIALPDFSAGAMENWGLVTYREVYLVVDE
                     NSTFASRQQVALVVAHELAHQWFGNLVTMKWWDDLWLNESFANMMEYVCVDTIEPSWN
                     IFEDFQTGGVPLALERDATDGVQSVHVEVKHPDEINTLFDGAIVYAKGSRLMHMLRRW
                     LGDADFAKGLHAYFEKHQYSNTIGSDLWDALGQASGRDVAAFMDSWLEQPGYPVLTVK
                     VENDVLKISQKQFFIGENEDKNRLWVVPLNSNWKGLPDTLETESIEIPGYAALLAENE
                     GALRLNTENTAHYITDYQGDLLEAVLAELETLDNTSKLQIVQERRLLAEAGHISYADL
                     LPVLDKLAKEESYLVVSAVSQVISALERFIDEGTDAETAFKGLVAKLARHNYDRLGFE
                     AKDGESDEDELVRQLAVSMMIRSNDAEASQVASQIFATHKENLAGLPAAIRSQVLINE
                     MKHHETKDLLALYLDTYTHATDAVFKRQLAAALAYSTDADNIQNLITSWKDKFVVKPQ
                     DLSAWYYQFLAHQATQKTAWSWARENWAWIKAALGGDMSFDSFVILPAHVFKTQQRLA
                     EYKEFFEPQLSDLALSRNIGMGIKEIAARVDLISREKAAVEAVVLQYGNA"
     gene            complement(15644..16084)
                     /locus_tag="VYO11_001460"
     CDS             complement(15644..16084)
                     /locus_tag="VYO11_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HEV1596008.1"
                     /translation="MTPQEMWNKYKQINPLIGDEIDAWAFGVEPDLLADLVFKGEKTA
                     TASAYDLYVLEDEPLPQVGTFDVILDSQNQSVCIVEITKVSVELFNQVSAQHAFKEGE
                     GDKSLAYWRQVHEDFFTDCLGEVGLTFTPESKVVLEEFRKVYPL"
     gene            complement(16059..16928)
                     /locus_tag="VYO11_001461"
     CDS             complement(16059..16928)
                     /locus_tag="VYO11_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PEP-utilizing enzyme, TIM barrel domain protein"
                     /protein_id="HEV1596009.1"
                     /translation="MRNQLALSGEKILEKIYPQLFHHVGMIRGEYLLRELNQNIILAS
                     CQQFVKDYLDTICSFYLDKEVWYRFSELTNTEANCLAGTREFFDEGHPLFGYRGTRRL
                     LACLDEFQAEAHVVTEVYQTNPNLSLIFPFVNDADQLKQAITVLRQYGFTGKVGTMIE
                     LPSAYFDLSSILETGISKIVVGMNDLTSFVFATMRNSQWHDMESPIMLDMLRDMQDKA
                     RKNKINFAVAGYLNTSFIQKMNQLGIKCIIHYSSIPEIFDLEIDHPDHLKHIKEESKK
                     LQRSTHDTARNVE"
     gene            complement(16906..17406)
                     /locus_tag="VYO11_001462"
     CDS             complement(16906..17406)
                     /locus_tag="VYO11_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEV1596010.1"
                     /translation="MEIKKHFGVYAVCLENGKLLCIEKTRGPYQHRYDLPGGSQQLGE
                     GLTETLTREVMEETGFTVRSYSNPRIYDVFVREELTNFMVHHVMALYDVEMNESAPQV
                     TTSEAVSDGANDSLGYIWMDIQEITEENASPLVLKVKSELLGFPELDKTSYMNWKVND
                     EKSTCP"
     gene            complement(17417..18115)
                     /locus_tag="VYO11_001463"
     CDS             complement(17417..18115)
                     /locus_tag="VYO11_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HEV1596011.1"
                     /translation="MTKRVLITGVSSGIGLAQARLFLEKGYQVYGVDQGEKPLLEGDF
                     HFLQRDLTLDLEPIFDWCPQVDVLCNTAGVLDDYKPLLEQTAQDIQEIFEINYIIPVE
                     LTRYYLTQMLENKKGIIINMCSIASSLAGGGGHAYTSSKHALAGFTKQLALDYAEAGI
                     QVFGIAPGAVKTAMTAADFEPGGLADWVASETPIKRWIEPEEIAELSLFLASGKASAM
                     QGQILTIDGGWSLK"
     gene            complement(18108..18374)
                     /locus_tag="VYO11_001464"
     CDS             complement(18108..18374)
                     /locus_tag="VYO11_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HEV1596012.1"
                     /translation="MKNVELKEKNMTFEEILPGLKAKRKYVRTGWGGAENYVQLFDTI
                     EQNGLALEMTPYFLINVSGEGEGFSMWSPTVCDVLATDWVEVHD"
     gene            complement(18440..19366)
                     /locus_tag="VYO11_001465"
     CDS             complement(18440..19366)
                     /locus_tag="VYO11_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase family oxidoreductase"
                     /protein_id="HEV1596013.1"
                     /translation="MRYITLGQDDKELSEIVLGMMRIKDKSVKEVEELVETALSVGIN
                     AFDLADIYGRGRCEELLGLVLKNRPDLREKMWIQSKCGIRIEEFTYFDFSKDYIIKSV
                     DGILQRLKIDHLDSLLLHRPDALMESDQVAEAFDLLYKQGKVRDFGVSNQNPMMMELL
                     KKDVKQPLAVNQLQLSAAFTPGFESAFHVNMEDSQAAMRDGSIFEYCQLHDVVIQAWS
                     VLQFGYFKGNFVGNEKFQALNQVLDRLAIKYGVTSSTIAISWILRYPAKMQAVVGTTN
                     PKHLREVSRAANFSLTRKEWYEIYLAAGNNLP"
     gene            complement(19441..20256)
                     /locus_tag="VYO11_001466"
     CDS             complement(19441..20256)
                     /locus_tag="VYO11_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1596014.1"
                     /translation="MKKMKYYEETSALLHEFSEENQKYFEELWESFNLAGFLYDEDYL
                     REQIYLMMLDFSEAERDGMSAEDYLGKNPKKIMKEILKGAPRSSIKESLLTPILVLAV
                     LRYYQLLSDFSKGPLLTVNLLTFLGQLLIFLIGFGLVATILRRSLVQDSPKMKIGTYI
                     VVGTIVLLVVLGYVGMASFIQEGAFYIPAPWDSLSIFTISLVIGIWNWKEAVFRPFVS
                     MIIAHLVVGSLLRYYEWMGISNVFLTKVIPLAVLFIGIFVLFRGFKKIKWSEV"
     gene            complement(20260..20580)
                     /locus_tag="VYO11_001467"
     CDS             complement(20260..20580)
                     /locus_tag="VYO11_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HEV1596015.1"
                     /translation="MKETQLLKGVLEGCVLDMIGQKERYGYELVQTLREAGFDTIVPG
                     TIYPLLQKLEKNQWIRGDMRPSPDGPDRKYFSLMKEGEERVSVFWQQWDDLSQKVEGI
                     KNGG"
BASE COUNT         6238 a         4525 c         3681 g         6285 t
ORIGIN      
        1 ttttaaaagt gttttgatgg cttggatttc ttctttagtt gattttatat tactattata
       61 taatactttt ttattttagt ctagtataaa tagcgagaaa tatctatcct atcttctaga
      121 atgtcttcca aacgagaaaa ctctcgtaaa caaagaggtt ttagaggcct atttaccgtg
      181 ggactaaagt tgtacaagaa aagtgcaaat aagaaatctc cagattagga actatccgtg
      241 agttctctag tctggagatt tttcaataga cttcgttatt ggacggttac caagttactc
      301 aaagtacaga tttgaagctg cagataagac tgacgaaatc actttaatac taaatgaaaa
      361 tcaaaaagca aactaagaag ctagcctcag gctgtacttg agtacggtaa ggcgacgctg
      421 acgtgatttg aagagatttt cgaagagtat aaaacactgt tttgaggtgg tggataaatc
      481 ggctgggtaa aaactcaatc tcaggagaaa atgaagtaaa tctccccaca actatagaaa
      541 aagatttgat tctgctcctc acacaataaa atctttttct tttattaaaa acgaatcgtt
      601 tcacgtgttt tctcatatga ggtaacaaag cgattggtta caccaggctc tgccacttcc
      661 aatgcttgag aaatcttgtc aaatgaagcg tgataatcaa attctttttc aaaaatatct
      721 aaagcttcgt taaatgcttc ttgaatgcgt tcatcaaatg agcgatagcg gttagaatat
      781 tgcaagagtt gctctgtcaa agttgcatat tgtacaatat tataagtttc cgtttctaaa
      841 gcttccatat cattcgttgc aatttcaaga actcgggtaa cagattcaat gttaatcatt
      901 ttttgttcta actcaaccat taaatcctcg gtattattgc ttgccgtaaa gaataacttc
      961 aagaaagttt gtggaatacc tggcagattg cgtttttcca tgtatcgctt gatagtatgg
     1021 agacgattga cataaacatt ggccttttga cgtgcattaa tatcatcttt ctcaatttgt
     1081 gtcaggcgct cactaactga aatttgctca tcttcaatat cttttagttg agtttgtaaa
     1141 tcctcaagat tttcttcaag aactgaataa gcttgggttg gttcttcttg attcgaagtt
     1201 acctcaacaa tagctgcctc aaaactctct aattctgtct gaatacgacg aacatggctt
     1261 gcagctgtct caggaagtaa ataggtcttg ttcaaacgtg caatatcttc tcccaataaa
     1321 gtattattct ctttcatatg ttgaagataa gttggaagag ttgcaagtag attttccact
     1381 actttctgag cagcaatttc tcgagtaaaa atatcataca aggcattgat ttcctcttgt
     1441 gcctgtccat tctcatattc ggcattatcc aattccaact gacgaatatt ctcttggttt
     1501 ttcttgaatg cttcataaag caagtggaaa cgcgcttcaa tatccgtttc aacaaaatga
     1561 taattagcat caattagttt acgataaccg gcttccaaat cctgtaattg atctggcaat
     1621 tctgtagaaa gcgtcgtaac caaggctgga acacgatcca caatatgact taaggccaaa
     1681 atgtgatttt ctgtattatc caaaatcact gcggcttcca cagggtcacc cgatgaattc
     1741 aaggttacaa attgtgaaaa ttcagattgg atattttcta attgtttttc aatttcatcc
     1801 aaggcttgac catactgttc tgaattttca gcaactctat gctgaagttc ctcaaataaa
     1861 tccaaagcat gaagaacacg accactattt ttagattctt gcttctctaa gtctgccaaa
     1921 gcattgcgaa ttgccgcaat atcttcttca atcaaagtaa tttgactctc aatttggtca
     1981 atttgatgac tggccttgag aaaacgaaat gaatggttat agccttctgc ttcaaagaga
     2041 ttattttcaa tatcggcaaa agagttgaga gataaatcga cccatttttg attccattca
     2101 cggaaagcca cttgactttg tccaatcaag tgcatatttt ttacagcttc tacttcatca
     2161 tttactggaa gattgtatag ttcttctttt ctttcttcta gcgcctctaa tctcccctcg
     2221 tttcgcttac gtagaaagat tgccactaca taagccagaa ctaaaatgac tgcaattgca
     2281 accattaaat aaattagttg tccattagac atatcaaact ccttttttac ttgaaacaat
     2341 cgtaacgatt atatcatatt ttttagacca agggaactac ttctccctat tttttagaca
     2401 tcaagtgtac tatagacagc attttcttcg ataaactcac gacgaggctc tactcgatcc
     2461 cccatcaaca tatcaaagat tttatctgct tctgcagcat catctacaga aactctagcc
     2521 atcaagcgat gttcgggatc catggttgtt tcccacagct gatgatcgtc catttcacct
     2581 agccccttat aacgctgaat agtcggtttg gtacgacctt cactataacg ggctaaagct
     2641 tcttggagtt tgatttcttg atctgcaccc ggctggatat attctttaat ctcgcttcca
     2701 accttgacac catagattgg tggttgggca atataaacat atccagcttc taggattggt
     2761 ttcatataac gataaatcaa ggttaaaaga agggtacgaa tgtgggctcc atcgacatcg
     2821 gcatcggtca tcaaaacgag tttttggtaa cgggctttcg aaacatcaaa ttctgcgcca
     2881 aatcctgttc ccatggctgt gaaaagacta cgaatttctt cgttggctag aatcttatcc
     2941 atacttgctt tttcaacatt caaaatctta ccgcgaattg gaaggatagc ctgaaactca
     3001 cggttacgac cagatttggc tgatccacca gctgagtctc cttcgacgat gaagagttct
     3061 gtttcagcag ggttattaga agaacagtct gctagtttcc ctggaaggtt ggaaatttcc
     3121 aaaccagatt ttttacgtgt gacttcacgc gcacgcttgg cagccacacg agccttggca
     3181 gccaaaattc ctttttctac gatacgtttg gcaatctgtg gattttccat gaggaaatcg
     3241 gagaaggctt cactgaagag gcgattggta atcttgacca cttcgctatt tcccaatttg
     3301 gtcttggttt gtccttcaaa ctgtggattt gggtgtttaa ctgagataac tgcagttaag
     3361 ccttcgcgaa catcttcccc tgttaaatta tcttcattgt ctttcagtaa cttattctta
     3421 cgagcataat cattgataac acgagtcagt gccgtacgga aaccttgttc atgcgttcca
     3481 ccttcatggg tatgaatatt attggcgaaa ctcatgacat tttcatggta acctgttgtg
     3541 tactgcatgg ctacctcaac tgtaatatca tccatctcac cgtctgtata gattggtgta
     3601 tcaaagatta catccttgtt ctcgttgata tattcaacgt aactagcaat cccaccttca
     3661 taatgataat gcttggtttg ttccaaacct tggcgcttat cagtgataga aatttgaaga
     3721 ccgcgattta gaaaggccaa ctcttgaatc cgtttattta atttatcaaa atcaaagatt
     3781 gttgtttcag tgaaaatttc tgggtccggt gtgaagtgaa ccgttgttcc agttctatct
     3841 gtatccccaa ccacctcaag gtctgcaaca acatgaccac gacggtattc ttggtaatga
     3901 atcttaccgt ttttatggac atgaacgtct aattgagtgg aaagggcatt aactactgac
     3961 gaccccaccc cgtgaaggcc acctgaaacc ttgtatccac caccgccgaa ctttcctcca
     4021 gcgtgaagga ctgtaaagac ggtctcaaca gcaggacggc ctgttttttc ctgaatatcg
     4081 actgggatac cacgcccatc atccacaaca gtaatcgaat catctggctc aataaaaact
     4141 tgaatatggc tggcaaatcc tgccaaggcc tcgtcaattg agttatcaac aatttcccag
     4201 actagatggt gaagaccttc ttttgaggtt gatccaatgt acatccctgg acgcatacga
     4261 acagcctcta agccctctaa aacttgaatt tgactggcat cataatcctg tgcctgcaga
     4321 tttttgattt cttctgtcat cttattcctt tttcttatat gtctaatact tgtcttaaat
     4381 tcacgatact ggtaaacaag tgggtatcaa gtcctgcagc ttgacctgct tcgatatcaa
     4441 tcggccgatc accaatgaca agaccagagc taatctgata cttttctctt aaataaagca
     4501 tggattcggg atttggcttt ctcttaaagc ctgagctaga agtcaccact tctgtaaaat
     4561 aagctgctat agaggttttt tctaaaattt ccaaaacctg atcatttcga tgagagacca
     4621 aaaaatgacg gccaccttga tttgaaatga cttccaatag gtcagaaact ccttcaaata
     4681 aaatcgggtg ttcaagctct ctggcttcat tttccttgta cttttctaaa aaattctcta
     4741 aattgggagc gaatgtctca atcgcaaaag gagtagaaac ctttaaagct tgatagacac
     4801 tgtcatggtc ttgtgtgata ccatacagtg ccaatgtttc aacaaatgca gctgttgaag
     4861 tttcataatt atccagtaaa gttccaccta aatcccagat gtaatcgtga tatttcatat
     4921 ccttcattat agcatttttt tatgaaaaaa gcgatgattt ccctgagttt tccacataaa
     4981 aaacgagaga ataactcccg ttttactgat ttttaccaaa gacatcttga tagagcattc
     5041 ctgttcgtaa actctctgcg tcccctccta gttgctccac caactcgtag gcaaaggcaa
     5101 gggctgttga aggaccccga ctggttgtca actgaccatc taccactact gtttccttga
     5161 cgtagtgacc atcaaggatt tgctcttgaa cgccgtcata acaagtgtat cgcttatttt
     5221 tcaatatctc tgcttgattg agggcaattg gtgccgcaca aatggctgct agtttcttcc
     5281 cttcttgctc gaagctttgc aattcttgaa tcaaggtctg attatcacgt aaatgtgcag
     5341 aaccaggcat acctccagga agaacaatca tatcatagtc tgataaatct ccatcaaaga
     5401 catgatctgc tcttacttgg attgcatgcg aacccgttac ttgctcttca aaaccaacca
     5461 tatcacatgt gatattggct cgacgcaaga catctacaac tgtcaaggct tcaatttctt
     5521 caaagccctg agctaacata actgctactt ttaccatgat tttctcctta tttaatttgt
     5581 tttaatacaa cctttttccg tttgaatggg acttttccgc tcttttcttc agctagatta
     5641 gtctggtaac tcatcgataa aagcaaacca acaccaatca gattactgat aatagctgat
     5701 cccccttgcg aaataaaagg caagggaatc cccgtcaaag gaagtagtcc agtcacagca
     5761 ccgatattct caaagatgtg gaagagcaac atcataatca aacctgtgga aatataagtg
     5821 tagaactggt tatttgattt aagagtaatc ttcaacatac ggtaaatcaa catgagatag
     5881 agggcaataa ccaggacaga gccaataaag ccaaaatctt ctgcaataac cgtaaaaatc
     5941 atatctgact ctcgaactgg gataagcaga ttcgaagcat taaatccctg accaaataag
     6001 ccaccactcc caatggcaat ctgtccttga gcctgctggt aagtcgttgt ttgggcaaac
     6061 tcaaagggat tgagccaagc caaaatccga ttaatttggt aggtcggcat tccaatctgg
     6121 tgaagaaaag ctcgtccgtc cttgctaata aagatagcta agaaaccagc aactcctgtt
     6181 acagcagtca caaatactgg gataataatt ttccaagaaa cccctgataa taaaacgatt
     6241 cctgagaaaa tggctacaaa aaccaaagcc gtccccaagt cactttgaag tgctaaaaga
     6301 actaggactg gaatggtaaa gagaatcatc cagaaaatta acaaaaagtc cagcggaacc
     6361 gtgcgtctcc attccttatg tttctttgta aattggacaa tgacacgagc caacatgagg
     6421 atataggata tcttcataaa ttctgacggt tggaataggg taattccatt tattgatacc
     6481 cagtttttgg cacccgttga tgcaactaag cttggattat aaaatacaat cggcaagatc
     6541 ataagtccca agcctaaaat atatagaaag ggggtcacct tccaaagaaa ttctgtatta
     6601 aagagcatga ccacaaaacc aatcacaagc cccaaggcaa tccaggcgac ctgctgccct
     6661 aaaatgggca gaatattatt gggataatca tgactaacgg ctatatagat agccaccaca
     6721 ccgatgacca gtagaaaaaa tactggcaag agcaaactgt aatcgactct tgagtcgaga
     6781 gaacgtttca tatatactaa ccttatactt tcatacaata ctatttatca aagttcatta
     6841 aaaaatctat caatagcctc gtcaacttcg gatcgagaga tggttttaac agtcgcttct
     6901 tctgctagag atgctactat ttgtttgccg tatcgttttc cgacgattct cctatccaaa
     6961 ataagagtta aggaacgttg gtattcacgt ctcatacttc ttcccaaagc ctgttttaaa
     7021 cgaataatgg ccattggcaa ttgataatca taaaaggcat ttttcccttc ttgattcagt
     7081 tcttgattaa tctttttcgt caagggttct tgaggatttt ggaaaggaag cctcggtaca
     7141 acttgaatca caaaaggatg gcttgaaaaa tcaactccct cccagaaact tgctgcacca
     7201 agcaagattt gttgttcacc tttttcaaag cgtttcttta gctgatgaac atccccattt
     7261 ttatactggg ccaagtggct aactgtaagt aaatccgata ctgctagaag catgtcttta
     7321 gcggtaaaga gaaccaaaat cggttgctgg aaagcttgaa tttccactag taaagcagct
     7381 acctctctgg catagacttc taaggaggtt tctgttacca gagggaaatc tttgaccata
     7441 accacttctt gttcctgttt tccccgagat tcaatcttga caaatttgac ttcaggatag
     7501 cctaaaaggt ctgccaaaga aaccctctga ctaatctcaa gagtagctga tactcccaag
     7561 acttggcaac tctcaggaag taaagaggac agaagagtac ggcctgattt tgtagaagaa
     7621 atctgaattt tcttttgact cgtttcagtt acttcaagcc agtaatcacc ttcagctgta
     7681 aaatagcgaa ccagctcatc aaagccttct acttctaatt ctgaaaaata ctgatggaga
     7741 ttgtccagag aatctaagat atttttccta gatttaccag actgaaattg ttctatcaag
     7801 tagagacact caaagcgaat actttctagt atccgttgtt gaaccctgtt ttcttctcct
     7861 actaaagcct tatcaattaa atcgataata gattgtatat cgtaggtctc ttgaagcaga
     7921 ttttctagag ctaacaaaat cttttggact tcatcaataa tcagtaaacg gtcactgaca
     7981 aattcaggat tatcttcaag tctggttacg agataggcat gattagtcac taaaagcttg
     8041 caagtctctg ccctttcttg actacgtttc caaaaatctt ccgtcacaaa taagttctgg
     8101 gatgataaat tcccatcatg acgaaggtct gctagaaaat gttggtaacg gtagagttgc
     8161 ccgatttcat ccaaatctcc tgtctctgtc tcagtaagcc agaccaagac ttgcatttta
     8221 aagcgtctaa ataagcgatt ttcatcattt tcctgcaagg aatgataaaa ggcatccaac
     8281 ttcagataat tttgtggtcc ctttaagcta tgaatatctg tatggaacac ttccttgagg
     8341 cgtttacctt cttcttccat gatttgattt tgaagaatct ttgtcggaac actaagaaca
     8401 atttgtcgct ctttggattg agataaagcg ggtaagagat agccataggt tttcccaatc
     8461 cctgtcggcg cttgaatcag agagacaggt tcatctttca atagcaagcc aacctcttta
     8521 gcaaaacttt cttgttcctc cctcacttca aggttcaaca gagaaatatt tttagaaaag
     8581 tcttgagata gttttcgtgg ctccagagaa gctgccattt tcttaaaata cagaccttga
     8641 acttggacca agtctggaga actcaggata gattggttgc gataagtttc ctcaataacc
     8701 aggtaggact catataggag agcgtcagcc atttccagca agcgttccaa gagaccttta
     8761 ggaagctggg tcatcttttc ccgtaaaaaa agaagtaatt ctgctgtagc ttgggcatct
     8821 gaaagggctg tgtgtgcgtg tttaagagga attcctaatt ctcgacacaa aatcggcaag
     8881 ctatattttt ccagttcagg gaaaaagacc tgggccaatt cgaccgtatc aacacgaggg
     8941 tttcttagct catagccttc aaaaaataaa ttttccgcca agagattagc atcaaactga
     9001 acattatggg ctacaaaaat cccatcctcc accaagtcaa agatttttct ggcaacttgc
     9061 gaaaaatcag gtgcttgcgc cagacgttgg tctgtcaatc ctgtcagttc tttgatatga
     9121 gcatccaagg gttcatgtgg attgacatcc gtcgtatagt gatcgacgat ttctccatcc
     9181 tcaatcacga caattcccac ttggataatt ttagccttac tacctgtgct agttgcctct
     9241 aaatccacca caacatagcg attaccaatc gttttcatta taaaaaatta taccaaaaaa
     9301 agggccattt ggcacctgca aacataggat aattttcaaa ctcaagaaca ctacttttct
     9361 tagaaatccc atcgaataga gcattctagc ctgctgattt ttttaaaata gtgaagaaat
     9421 acgaaaaatt gagagaagaa atgttttcat cttccttctc tcaacgaatc atgtatttta
     9481 tttaaccatg tcaggatcgt agtcataaaa tcctgtatca aggaaacggt ttttagggtg
     9541 aagtttacga acttcttcat ccagcaagaa ggcttggtca tggctaaagt tgccctcttg
     9601 aatcaagcta cgcgcttgga taaagagttt tgcaatctca acaaagttct gaccaggagt
     9661 gtagagccct tctagtttcc agcgagtaaa gccatgctcc accaattctg ttaatttgat
     9721 catcaaatca aggtcattgt tggcaaagat atgggtccca tgattatctt caaaaatgga
     9781 atagtggctc tctggatcac ttggctcagc caagaagagg tcacgtttat gcgtcttttc
     9841 atcatcgata tgtgtaaagt tatagtagtt ttgcaagagt ggacgtttag aatgatggat
     9901 gacgctagca ccgtaaacca aaacttcagc aggaatttcc aaaatctctg gcattttgaa
     9961 aagttcagct gatggaattt cacgcgccaa aacagcctca gatgcgccag ccttttgtcc
    10021 ccagaagtta atctgacgac tgctagttac catggttgaa gcatcgtaga tggtcttaaa
    10081 tgaataacca tcgcggttaa ctacgtaaaa gacgcctgca tccccaatcg taatatagtc
    10141 tgtcttgatt tcttccaaga agtctaagaa aggcttgata cggtccatca tatcttggtg
    10201 catgagagca ttgaccgcaa cgagcaattc cttaccagca tcatgaacca acttagcgat
    10261 ttcacgtaat tggtcataac taaaggtcgt tggcagacga aggccaaaat ctttctcacc
    10321 gacatagata cggtctacgc cagcttcgag tagttgttca acttgttcaa tactttcagc
    10381 agttgctgta atgacaatct tttccataag aaaaattata ccacatttct ccaaaatcat
    10441 ccatgctttg aaaatgaaaa gggactttat tctttttgta acctttctgt aataattctc
    10501 tgccgaaaaa atgataaaat aggtatgtac tgttaaggag agaatcatgc ccgtaagaaa
    10561 attacaatcc tatgaggtag actatcaaga agaattaaac cagcagcttc ctcattacca
    10621 agcttataca cctgaagcgc aatctgatgc caatctcaag gaaatcctat tttttattaa
    10681 tatcgctgtt ttttgtatct gtattgctat ctttagtttt atctttttag cattaaaatt
    10741 atcaactgct cttgcctttg ccgcagcaat cggattcagc ttacttgttt taaaagttca
    10801 acggtctatt atcaaacgaa aacgtagaag ataaatccaa aatatcgccc caattggagc
    10861 gatattttta ttttttcttt ttagatggtg tctgaatggc aatcttcact tcaaagattg
    10921 ttcccttggg tttattatct ttgacagtaa cagttccttt tagagcatct acaatttgct
    10981 tggctaggga taatcctaat ccaaaaccac ctttttgccg ggttctagcc ttgtctactc
    11041 gataaaaacg gtcaaaaatt ttctttttat cttctgtcga aataccgatt ccattatcag
    11101 aaacaagtaa ataaagattg cgatcggtcg ccgagataag aaaatcaatt tcaccatcct
    11161 cctcagtata cttgacggca ttatcgaaaa gaatggtcat cagttgtttc agaagaagct
    11221 gatctgtgac aattgttcga tggatacgat tttcaaaacg gaagacacga ttattttccg
    11281 aagcaatcat ctcatagttt gtgaaagttg tattaaaaaa gctagttgga acttctgcaa
    11341 gctccggctt aatcccatca tctctccgag ctaagttcag caagcttgtc gttaaaaaac
    11401 gcatatttcg gacttcttcc aaactcgatg caatgctttc gctcacatcc ataatggtag
    11461 cttctggctt acgaaaaagg gtctctaagc gattttgcaa aactgcgagt ggagttcgta
    11521 actcatgact ggcattttcc acaaaagact gttgcttctg catactctca agcaggggcc
    11581 taacactgac cctagctaga tagagactgg caagtaaaga caaaatccag aaactagcca
    11641 tcacgaccac aatcaattgc tcatgctttt gactagcctg ctccaactga ctggtattaa
    11701 tcaagacagc agcatacttg atattggttg aaaccgaact aatattggtc tccatcaaaa
    11761 tcacacgata gatttcttcc tgcccatagc tattaaaaac ctgaatctgg tagatatgtc
    11821 ctagttcttt cttttctaac ttaatcttat ccaagcccaa aaatcgattt ccagaaagaa
    11881 gttgagtaaa gtctttatca aagagaatga cttccgtatt ggaactgaca ttaggtttta
    11941 tttctacttt actagcgtcc gccctagcat tttctaaatc tttaatctct tctgttgccc
    12001 tatttatagc cagctgaata actgcttgag gattttcact cagtccatga agcttatcgt
    12061 ccaccgaagt ataaagactc gaatgcatga cttgtaaaat aatcagagtc attgtagaaa
    12121 aaatcagggt gaagacaccg aagttgcgga taaaataact aaagtcatcc gcataccatg
    12181 tttttttaag tttactgaac atcttttaaa agatacccaa cactacgcaa ggtttgcaaa
    12241 ttctctgcaa aagtggttcc ctttaatttc ttacggactt ttgaaacata gacttcgaca
    12301 accgaaatcg ttgtatcact atcaaatccc catagacggt caaaaatctg cgtcttaggc
    12361 aaaatcacat tttgattttg aaggaaataa actagtaaat cgaactcttt ccccagcaat
    12421 tcgacaggag tatcttcaac tttaacggta ttggttgata aattaaccac gatattccca
    12481 taagtcaagg tgttttcatt aaacttccct gaacgtttga gaagggcctg aattcgcatt
    12541 ttaagttctt ctaggtagaa aggtttggtc agataatcat ccgctcccag ttcaaatcca
    12601 tgtcccttgt catccaaact ttccttggca gtcataatca gaactggtgt cgtaattccc
    12661 ttttcacgca attcttttaa gacttggaaa ccattttttt ctggcaacat caaatccagc
    12721 aaaatcaagt catagacacc actctcagct tcgtagagac cttcttctcc atcaaatacc
    12781 tgcataacat ccgcaaaatc gtctaaaaag tcaaatactg aatttgacag acctaggtca
    12841 tcctcaacca ataagatttt tatcatgaga aactcctcct tattaaaact attataccaa
    12901 atttgcctta aaaaaaactc aactctctgc attttacatg agatagctga gttttctttt
    12961 tattttaggc ttatttatgc atttccgtat tgaagaacaa ctgcttcgac tgcagctttt
    13021 tcacggctaa tcaagtcaac acgtgctgca atttccttga ttcccatacc gatgttacgg
    13081 ctaagagcaa ggtcagaaag ttgcggctca aaaaactcct tgtattccgc caagcgttgc
    13141 tgagtcttaa atacatgagc aggaaggata acaaagctat caaagctcat atctcctcca
    13201 agggctgcct taatccaagc ccagttttca cgcgcccaag accaagctgt tttctgagtt
    13261 gcttgatgag ctaggaattg gtaataccaa gcagacaagt cctgtggttt gaccacaaat
    13321 ttgtccttcc aagaagtaat caagttttgg atattatccg catctgtact gtatgcaaga
    13381 gctgctgcca actggcgttt aaagacagca tctgttgcgt gagtataagt atcaagataa
    13441 agtgctaaca agtctttagt ctcatgatgt ttcatctcat taatcagaac ttgtgagcga
    13501 atagctgctg ggagtcctgc aagattctcc ttgtgtgttg cgaagatttg gctagcgact
    13561 tgactagctt ctgcatcatt tgagcgaatc atcatcgaaa cagccagctg acgaaccaat
    13621 tcatcctcat ctgattctcc gtctttagct tcaaaaccaa gacggtcata gttatgacga
    13681 gccaatttag caaccagtcc tttgaaggct gtttcagcat ccgttccttc atcaataaag
    13741 cgctcaaggg ctgaaatcac ttgagaaaca gctgaaacca ccagataaga ctcttcctta
    13801 gcaagtttat caagaactgg aagcaagtct gcataagaaa tgtgccctgc ctcagccaac
    13861 aaacgacgtt cttgaacaat ttgcagtttg cttgtgttat caagtgtctc tagctcagca
    13921 agaacagctt ctaacaagtc tccttgatag tcggtaatat agtgggcagt attttcagtg
    13981 ttgagacgaa gagctccttc attttcagca agaagagctg cgtagccagg gatttcgata
    14041 ctttcagttt cgagtgtatc aggcaagcct ttccagttgc tattgagggg caccacccag
    14101 agacggttct tgtcttcgtt ctcaccgatg aagaattgtt tttgtgaaat cttcaagaca
    14161 tcattttcaa ctttgacagt aagaactggg taaccaggct gttccaacca agaatccatg
    14221 aaggctgcga catcacgtcc tgacgcttga ccaagggcat cccaaaggtc actaccaatg
    14281 gtattgctgt attggtgttt ttcaaagtag gcgtgcaaac ctttagcaaa atcagcatct
    14341 cctagccaac ggcgaagcat gtgcatgaga cggcttcctt tggcatagac gatagcgccg
    14401 tcaaagagtg tattgatttc atctggatgt ttaacttcga cgtggacaga ctgaacgcca
    14461 tcagtagcgt cacgttcaag agcaagaggt actccacctg tttggaaatc ttcaaagata
    14521 ttccagcttg gttcgatggt atccacacag acgtattcca tcatattagc gaaactttca
    14581 ttgagccaaa ggtcatccca ccatttcata gtcacgaggt tcccaaacca ttggtgagcc
    14641 aattcatggg ccacaacaag ggcaacttgt tgacggctag caaatgtaga gttctcatcg
    14701 acaaccaagt aaacttcacg gtaggtcaca agaccccagt tttccatagc accagctgag
    14761 aagtcaggaa gagcgatgtg gagagattga ggaattgggt acttaactcc atagtaatct
    14821 tcgtaaaact cgatagagcg aacagcgata tccagtgaga aatcaagatt tgaaagtgga
    14881 tgtgctttgg ttgagtagac acctaccagg gtaccatttt tagttttagc ggtcacccct
    14941 tgcaaatcac cagcaacaaa ggccaacaag taagaagaca tgcgaggtgt tgtctcaaac
    15001 ttccagatac ctgtttcctt acggttttca acatcgattt ctggcatgtt tgacaaggcc
    15061 aattcacctt ctgcttggtc aaagcgaaga gagaggtcaa aagttgcttt ggcttcaggc
    15121 tcatccacac atgggaaagc ttcgcgcgca aaatggctct cgaactgagt agacaagacc
    15181 tccttcttga ctccatcaac tgtataataa gaagggtaaa tccctgtcat gttgtctgta
    15241 attttaccag aaaaggcaag aaccaattca acttgaccag cctcagccaa ttcgatatga
    15301 agggcttcat tgtcatggtc aactgtaaat ggacgagctt gacctgcaac ttctacagag
    15361 gtgatttcca agtctttttg gtggagggag atgcggtcac tctgtgcttg accagtgatg
    15421 gtcactttcc cagaaaaagt cttggtctca cgactcaaat ctaaaaataa atcataatgt
    15481 tcaggaacaa attgcttaat aaaatgttca actgcttgca tagttttctc ctattctaag
    15541 tttaagagct gctgctcttc ttcaaacaaa cttattatat catattttgc ttgagaaaaa
    15601 aggattggac agcgatttcc aaaactttct tccttctaat agtctacagt gggtagacct
    15661 tgcgaaattc ttctaaaaca accttgcttt caggtgtaaa agtcagccct acttcaccca
    15721 aacagtctgt gaaaaagtcc tcatgaacct ggcgccaata ggcaagtgat ttgtctccct
    15781 caccttcctt aaaggcatgt tgcgcagaaa cttgattgaa gagttcaaca gaaacctttg
    15841 taatttcgac aatgcagaca gactgatttt gactatctaa aatgacatcg aaggtcccta
    15901 cttggggaag tggttcgtct tctagtacat agaggtcata ggctgatgct gttgctgtct
    15961 tttctccttt aaacaccaaa tccgctaaaa ggtctggttc aactccaaaa gcccaagcat
    16021 cgatttcatc tccgatcaaa ggattgattt gtttgtattt attccacatt tcttgcggtg
    16081 tcatgggtgc tcctttgtaa ttttttactt tcttctttta tgtgtttaag atgatctgga
    16141 tggtcaatct ctaaatcaaa aatctctgga atagaactgt agtggataat gcacttgata
    16201 cccaactgat tcattttttg tatgaaagaa gtattcagat agcctgctac agcaaaatta
    16261 atcttgttct ttcttgcttt atcctgcata tctcttagca tatctaacat tattggactt
    16321 tccatatcat gccattgact gtttctcata gtcgcaaaaa caaaggaagt caaatcattc
    16381 attccaacta caatctttga aatgcccgtt tccagtatac tagataagtc aaaatacgct
    16441 gacggtaatt caatcatcgt tccgactttc ccagtaaagc catactgacg caatactgta
    16501 atagcttgtt ttaattggtc ggcatcattg acaaaaggaa aaataagaga cagattggga
    16561 ttggtttgat aaacttctgt aacgacatgt gcttcagcct gaaattcatc caaacacgcc
    16621 agtaaacgcc tggttcctct atagccaaac aagggatgcc cttcgtcaaa aaactctcta
    16681 gtccccgcta aacaattggc ttctgtattc gttaattcag aaaaacgata ccaaacttcc
    16741 ttatctaagt aaaaggagca aatagtatca agataatctt ttacaaattg ctgacaactt
    16801 gctaatatga tgttttgatt aagctctctc aacaaatatt ccccacgaat catgccgacg
    16861 tggtgaaata gttgaggata aattttttca agaatttttt cgccactaag ggcaagttga
    16921 tttctcatca ttcaccttcc aattcatgta agaagtcttg tccagttctg gaaatcctaa
    16981 taattcagac ttaaccttca agactaatgg cgatgcattt tcttctgtaa tctcttgaat
    17041 atccatccaa atatatccaa gtgaatcatt cgcaccatca gacacagctt ccgaagtcgt
    17101 aacttgaggt gcactctcat tcatttcaac atcatacaag gccatgacat ggtgaaccat
    17161 aaaatttgtt aactcttctc tgacgaaaac atcgtagatt cgaggattag agtagcttct
    17221 aacagtaaat cccgtctctt ccataacttc tctagtcagc gtttccgtca gtccttcacc
    17281 aagttgctgg ctgcctccag gtagatcata ccgatgttga taagggcctc tcgttttttc
    17341 aatgcagagt aacttcccat tttctaagca aacagcgtag actccaaagt gttttttgat
    17401 ttccatccaa ctcctcctac ttcaaagacc agccaccatc tattgtcaag atttgtcctt
    17461 gcatggcgct cgcttttcca cttgctaaaa aaagactaag ctctgctatt tcctctggct
    17521 caatccagcg cttgattggg gtttcactag ccacccagtc agccaaacca cctggttcaa
    17581 aatccgcagc ggtcatagct gtcttgactg ctcctggagc gataccaaag acctgaatcc
    17641 cagcttcagc atagtctaga gccaactgct tggtgaagcc agccaaggca tgcttggatg
    17701 aagtataggc gtgaccacct ccacctgcta ggctagaagc aatggaacac atattgatga
    17761 tgattccctt tttattttcc agcatttgtg tcaaataata ccgagtcaac tctactggaa
    17821 taatgtagtt gatttcaaaa atctcttgaa tgtcctgcgc cgtttgttcc aacagtggtt
    17881 tgtaatcatc caaaactcca gcagtattac acaaaacatc cacctgaggg caccagtcaa
    17941 aaataggttc caagtccaag gtcaaatctc tctgtaaaaa gtgaaaatca ccctctaaga
    18001 gtggcttttc accttggtca actccataaa cttgatagcc cttctctaaa aagaggcgag
    18061 cttgagccaa tccgatccct gaactcactc ctgtaatgag tacacgttta gtcatgcact
    18121 tctacccaat ccgttgccaa aacatcacaa actgtcgggc tccacatgga aaaaccttct
    18181 ccttcgccag aaacgttgat taggaaataa ggtgtcattt caagtgcaag cccattttgc
    18241 tcgatggtat caaagagttg gacatagttt tccgcacctc cccaaccagt tcgtacatat
    18301 tttctcttag cctttaaccc aggcaggatc tcttcaaatg tcatgttttt ctcctttaat
    18361 tctacattct tcatttaatt atagcaaaaa accgctttat acggcttttt gaatgtgagt
    18421 tattcaaacc tgctactact tacggcaaat tattccctgc agcaagataa atttcatacc
    18481 attcttttct tgttaagcta aagtttgccg ctcggctaac ttctctcaag tgcttaggat
    18541 ttgttgtacc tacgactgcc tgcatttttg ctggataacg caatatccaa gaaatggcaa
    18601 tagttgaaga ggttactcca tatttaatag ctaaacgatc aagtacttga tttaaagctt
    18661 gaaatttctc atttccaaca aaatttcctt taaaataccc gaattgtaag acagaccatg
    18721 cttgaatgac cacatcgtgt aattggcaat attcaaaaat gctgccatct cgcatagctg
    18781 cttgactatc ttccatatta acatgaaaag ctgattcaaa tcctggagta aaagccgcac
    18841 tcaattgtag ctgattaaca gctaacggct gcttgacatc ttttttaagc aactccatca
    18901 tcataggatt ttgattagaa actccaaaat ctcgaacttt accttgttta taaaggagat
    18961 caaaggcttc tgctacttgg tcagattcca tcaaagcatc tggtcgatga aggagcaagc
    19021 tatctagatg atcaatcttc aatctttgca aaataccgtc tactgatttt ataatatagt
    19081 ccttagaaaa atcaaaatag gtaaattctt caatgcgaat gccacatttg gactgaatcc
    19141 acatcttttc tcttaaatct ggacgatttt ttaggacaag acctaacagt tcttcacaac
    19201 gaccacgacc ataaatatca gccaagtcga aggcattgat tccaacagaa agtgctgttt
    19261 ctacaagctc ttcaacttct tttacagatt tatcttttat tctcatcatt ccgagaacaa
    19321 tttctgataa ttctttgtca tcttgaccaa gagttatgta tctcatcaaa tttttctcct
    19381 ttaatttcta acattcttcc cttcattata acaaaaaacc gctttgcaac gactttttga
    19441 ctatacttca ctccatttta tcttcttaaa cccacggaac aagacaaaga ttccaataaa
    19501 gaggacagct aaaggaataa cttttgtaag gaaaacattt gaaattccca tccactcata
    19561 ataacggagc agagaaccca ccacaagatg ggcaataatc atactgacaa atggacgaaa
    19621 gaccgcttct ttccaattcc aaataccgat aactagcgaa atcgtaaaga tagacaaact
    19681 atcccaggga gccggaatat aaaaggctcc ttcttgtatg aagcttgcca ttcctacata
    19741 tcctaaaaca actagaagaa ctatagtccc aacaacaatg taagtgccaa ttttcatttt
    19801 aggagaatct tggactaaac ttcttcgtaa aattgtggcc acaagtccaa atccaatcag
    19861 aaaaataaga agttgcccta aaaatgtgag caaattgact gttaagagag gacctttaga
    19921 aaaatcactt agtagttgat aataacgtaa taccgccagg acaagaattg gcgtcaaaag
    19981 ggactctttg atagaactgc gaggtgctcc cttgagaatc tctttcatta tttttttagg
    20041 attcttacct agataatcct ctgcactcat gccatctcgt tctgcttctg agaaatctag
    20101 catcatcaaa tagatctgct ctctgagata gtcttcatca tagagaaatc cagcaagatt
    20161 aaaactttcc cacaactcct caaaatactt ttgattctcc tcagaaaact catgtagcaa
    20221 agcgcttgtt tcttcgtaat acttcatttt cttcatggtt taacccccat tcttaatccc
    20281 ttctactttt tgactcaaat cgtcccattg ttgccaaaag actgagacac gctcttctcc
    20341 ttctttcatt aatgaaaaat acttccgatc tggaccatct ggcgacgggc gcatgtcgcc
    20401 tcttatccat tgattttttt ctaacttttg caacaaagga taaatagttc ctggaacgat
    20461 agtatcaaat ccagcctctc gcaaagtctg aaccaactca taaccatacc gctctttttg
    20521 accaatcata tccaagacac aaccttcaag aacacctttt aatagctgag tttctttcat
    20581 cacttctccc ttctaatcta ttttgtaata cctactagta acttcaccta tagtatatta
    20641 cttctacact agtttgtaaa gcataatagt taatactctt cgaaaatctc ttcaaaccac
    20701 gtcagcgtcg ccctaccgta tgtatggtt
//
LOCUS       DAVLXH010000037        20512 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00028199
            SAMN33607166-rid17955573.denovo.037, whole genome shotgun sequence.
ACCESSION   DAVLXH010000037 DAVLXH010000000
VERSION     DAVLXH010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607166
            Sequence Read Archive: SRR23725544
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20512)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20512)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721421.1
            Genome Coverage       :: 115x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:42:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,210
            CDSs (total)                      :: 2,161
            Genes (coding)                    :: 2,023
            CDSs (with protein)               :: 2,023
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 73 of 138
            Pseudo Genes (incomplete)         :: 60 of 138
            Pseudo Genes (internal stop)      :: 40 of 138
            Pseudo Genes (multiple problems)  :: 31 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20512
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607166-rid17955573.denovo.037"
                     /strain="AUSMDU00028199"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1349"
     gene            complement(<1..367)
                     /locus_tag="VYO11_001468"
     CDS             complement(<1..367)
                     /locus_tag="VYO11_001468"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1596016.1"
                     /translation="MDLLEKECLKCDKNFQQGDIWNYYYLSDKVPAQGWKIHISSQIK
                     DAVNIFKIVYKLSQLNNCSFKVVKNLEELKKINSPREMSPTANKFITLYPKSESEAKS
                     MICNLTNRLSEFKAPKILSD"
     gene            916..1593
                     /locus_tag="VYO11_001469"
     CDS             916..1593
                     /locus_tag="VYO11_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000624068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HEV1596017.1"
                     /translation="MISKRLELVASFVSQGAILLDVGSDHAYLPIELVERGQIKSAIA
                     GEVVEGPYQSAVKNVEAHGLKEKIQVRLANGLAAFEETDQVSVITIAGMGGRLIARIL
                     EEGLGKLANVERLILQPNNREDDLRIWLQDHGFQIVAESILEEAGKFYEILVVEAGQM
                     KLSASDVRFGPFLSKEVSPVFVQKWQKEAEKLEFALGQIPEKNLEERQVLVDKIQAIK
                     EVLHVSK"
     gene            1580..2377
                     /locus_tag="VYO11_001470"
     CDS             1580..2377
                     /locus_tag="VYO11_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000881127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HEV1596018.1"
                     /translation="MLASEVIQAYEAFCPQEFSMEGDSRGLQIGTLDKGIQRVMVALD
                     IREETVAEAIEKGVDLIIVKHAPIFRPIKDLLASRPQNQIYIDLIKHDIAVYVSHTNI
                     DIVENGLNDWFCQMLGIEETTYLQETGPERGIGRIGNIQPQTFWELAQQVKQVFDLDS
                     LRMVHYQENDLQKPISRVAICGGSGQSFYKDALAKGADVYITGDIYYHTAQDMLSDGL
                     LALDPGHYIEVLFVEKIAALLTQWKEKKGWELEILPSQASTNPFRHI"
     gene            2394..3497
                     /locus_tag="VYO11_001471"
     CDS             2394..3497
                     /locus_tag="VYO11_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HEV1596019.1"
                     /translation="MKKVAIIGAGIVGATAAYYLSRESDLEVTVFDHEQGQATKAAAG
                     IISPWFSKRRNKAWYKMARLGADFYVDLLADLEKSGQKIDFYQRSGVFLLKKDESKLE
                     ELYQLALQRREESPLIGQLAILDQASANELFPGLQGFDRLLYASGGARVDGQLLVTRL
                     LEASHVKLVKEKVTLTLLSSGYQIGEEVFDQVILATGAWLGDMLEPLGYEVDVRPQKG
                     QLRDYQLAQDMEAYPVVMPEGEWDLIPFAGGKLSLGATHENDMGFDLTVDEPLLQQME
                     EAALPHYPVLARATSRAERVGIRAYTSDFSPFFGQVPELAGVYVASGLGSSGLTTGPI
                     IGYHLAQLIQDKELTLDPLNYPIENYVKRVKSE"
     gene            3504..3650
                     /locus_tag="VYO11_001472"
     CDS             3504..3650
                     /locus_tag="VYO11_001472"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1596020.1"
                     /translation="MKIKEQTRKLAAGYSKHCFEVVYRTDEVSNHTHGKATLTWFELD
                     FRRV"
     gene            3753..4772
                     /gene="galE"
                     /locus_tag="VYO11_001473"
     CDS             3753..4772
                     /gene="galE"
                     /locus_tag="VYO11_001473"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HEV1596021.1"
                     /translation="MQEKILVTGGAGFIGTHTVIELIQAGHQVVVVDNLVNSNRKSLE
                     VVERITGVEIPFYEADIRDTVTLRDIFKQEEPTGVIHFAGLKAVGESTRIPLAYYDNN
                     IAGTVSLLKAMEENNCKNIIFSSSATVYGDPHTVPILEDFPLSVTNPYGRTKLMLEEI
                     LTDIYKADSEWNVVLLRYFNPIGAHESGDLGENPNGIPNNLLPYVTQVAVGKLEQVQV
                     FGDDYDTEDGTGVRDYIHVVDLAKGHVAALKKIQKGSGLNVYNLGTGKGYSVLEIIQN
                     MEKAVGRPIPYRIVERRPGDIAACYSDPAKAKAELGWEAELDITQMCEDAWRWQSKHP
                     NGFED"
     gene            4774..5727
                     /locus_tag="VYO11_001474"
     CDS             4774..5727
                     /locus_tag="VYO11_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV1596022.1"
                     /translation="MMISIIVPCLNEEEVLPLFYQALEALLPDLETEIEYVFVDDGSS
                     DGTLELLKAYREQNPAVHYISFSRNFGKEAALYAGLQYATGDLVVVMDADLQDPPSML
                     FEMKNVLDKNVDLDCVGTRRTSREGEPFFRSFCAVLFYRLMQKISPVALPSGVRDFRM
                     MRRSVVDAILSLTESNRFSKGLFAWVGFKTHYLDYPNVERQAGKTSWSFRQLFFYSIE
                     GIVNFSDFPLTIAFVAGLLSCFLSLLMTFFVVVRTLILGNPTSGWTSLMAVILFLGGI
                     QLLTIGILGKYISKIYLETKKRPLYLIKEKSDLPDFTEKIK"
     gene            complement(5789..5995)
                     /locus_tag="VYO11_001475"
     CDS             complement(5789..5995)
                     /locus_tag="VYO11_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HEV1596023.1"
                     /translation="MKITLIPERCIACGLCQTYSDLFDYHDNGIVRFYDDPDQLEKEI
                     SPSQDVLEAVKNCPTRALIGNQEA"
     gene            6047..6523
                     /locus_tag="VYO11_001476"
     CDS             6047..6523
                     /locus_tag="VYO11_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM domain-containing protein"
                     /protein_id="HEV1596024.1"
                     /translation="MAKEPWQEDIYDQEESRAERRHRNHGGADRMANRILTILASIFF
                     VIVVVMVIVLIYLSSGGSNRTAALKDFHDSDASVVQISSSSSSHPEQSSEPESTSSSS
                     EEAANPEGTIKVLAGEGEAAIAARAGISIAQLEALNPGHMATGSWFANPGDVIKIK"
     gene            6532..7203
                     /locus_tag="VYO11_001477"
     CDS             6532..7203
                     /locus_tag="VYO11_001477"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HEV1596025.1"
                     /translation="MKTIQIAIDGPASSGKSTVAKIIAKDFGFTYLDTGAMYRAATYM
                     ALKNQLGVEEVEALLALLDQHPISFGRSETGDQLVFVGDVDITHPIRENEVTNHVSAI
                     AAIPEVREKLVSLQQEIAQQGGIVMDGRDIGTVVLPQAELKIFLVASVDERAERRYKE
                     NIAKGIETDLETLKKEIAARDYKDSHRETSPLKQAEDAVYLDTTGLNIQEVVEKIKAE
                     AEKRM"
     gene            7334..7672
                     /locus_tag="VYO11_001478"
     CDS             7334..7672
                     /locus_tag="VYO11_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002920966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HEV1596026.1"
                     /translation="MNNLPNCPKCNSEYVYEDGALLVCPECAHEWNPAEVAEVEEGLV
                     AIDANGNKLTDGDTVTLIKDLKVKGAPKDLKQGTRVKNIRIVEGDHNIDCKIDGFGAM
                     KLKSEFVRKI"
     gene            7675..8304
                     /locus_tag="VYO11_001479"
     CDS             7675..8304
                     /locus_tag="VYO11_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Pr6Pr family membrane protein"
                     /protein_id="HEV1596027.1"
                     /translation="MSKHYKLVFYSRIFLFLAAFTGVYLEITRHGGFGMLLYYTVLSN
                     LLVTIFTLYLLKVMSRVGENWQRPSLLRLKGGVTMSIMITCVIYHFLLAPIATNFYTL
                     ENFLCHYIVPIWFLADTLFFDKQGQYKIWDPAVWTILPFLYMMFALFNGLVLKLNIPN
                     AKDNPFPYFFLNVNKGWNVVFKWCLIIFVAYMVAGFIFYFIKQIKRKSS"
     gene            8544..9695
                     /locus_tag="VYO11_001480"
     CDS             8544..9695
                     /locus_tag="VYO11_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEV1596028.1"
                     /translation="MKQFLERASILALSLVLITSFSISSALPAMFDYYQGYSKEQIEL
                     LVSLPSFGIMMMLLLNGFLEKIFPERLQISLGLLILSLSGTAPFWYQAYPFVFGTRLL
                     FGLGLGMINAKAISIISERYQGKRRIQMLGLRASAEVVGASLITLAVGQLLAFGWTAI
                     FLAYSAGFLVLPLYLLFVPYGKSKKEVKKRAKEASRLTREMKGLIFTLAIEAAVVVCT
                     NTAITIRIPSLMVERGLGDAQLSSFVLSIMQLIGIVAGVSFSFLISIFKEKLLLWSGI
                     TFGLGQIVIALSSSLWVVVAGSVLAGFAYSVVLTTVFQLVSERIPAKLLNQATSFAVL
                     GCSFGAFTTPFVLGAIGLLTHNGMLVFSILGGWLIVISIFVMYLLQKRA"
     gene            10013..10762
                     /gene="truA"
                     /locus_tag="VYO11_001481"
     CDS             10013..10762
                     /gene="truA"
                     /locus_tag="VYO11_001481"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HEV1596029.1"
                     /translation="MTRYKATISYDGYAFAGFQRQPHARSVQEEIEKTLTRLNKGQAI
                     TVHGAGRTDSGVHALGQVIHFDLPYQMDEEKLRFALDTQSPEDIDVISIELVADDFHC
                     RYAKHSKTYEFIVDRGRPKNPMRRHYATHFPYPLDVERMQIAIKKLEGTHDFTGFTAS
                     GTSVEDKVRTITEASLIVDETGQFLTFTFSGNGFLYKQIRNIVGTLLKIGNNRMPVEQ
                     IDLILEKKDRQLAGPTAAPNGLYLKEIRYEE"
     gene            10752..11525
                     /locus_tag="VYO11_001482"
     CDS             10752..11525
                     /locus_tag="VYO11_001482"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HEV1596030.1"
                     /translation="MKNNRILALSGNDIFSGGGLSADLATYTLNDLHGFVAVTCLTAL
                     TEKGFEVFPTDDTIFQHELDSLRDVEFGGIKIGLLPTVSVAEKALDFIKQRPGVPVVL
                     DPVLVCKETHDVAVSELCQELIRFFPYVSVITPNLPEAELLSGQEIKTLEDMKTAAQK
                     LHDLGAPAVIIKGGNRLSQDKAVDVFYDGQTFTILENPVIQGQNAGAGCTFASSIASH
                     LVKGDKLLPAVESSKAFVYRAIAQADQYGVRQYEANKNN"
     gene            11503..11964
                     /locus_tag="VYO11_001483"
     CDS             11503..11964
                     /locus_tag="VYO11_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEV1596031.1"
                     /translation="MKQTKTTKIALVSLLTALSVVLGYFLKIPTPTGILTLLDAGVFF
                     AAFYFGSREGAVVGGLASFLIDLLSGYPQWMFFSLVNHGLQGFFAGFKGKSQWLGLIL
                     ATIAMVGGYALGSTLMNGWAAALPEILPNFMQNMVGMIVGFILSQSIKKIK"
     gene            complement(12223..12426)
                     /locus_tag="VYO11_001484"
     CDS             complement(12223..12426)
                     /locus_tag="VYO11_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1596032.1"
                     /translation="MIKLYSPYAFLSKYLGAILLSFFCYYAKEIGCSNLTLSVWNDNE
                     GALRFYQRQGMKPQETTMEMRID"
     gene            complement(12419..13501)
                     /locus_tag="VYO11_001485"
     CDS             complement(12419..13501)
                     /locus_tag="VYO11_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HEV1596033.1"
                     /translation="MSKLQQILTYLESEKLDVAVVSDPVTINYLTGFYSDPHERQMFL
                     FVLADQEPLLFVPALEVERASSTVSFPVVGYVDSENPWQKIKHALPQLDFKRVAVEFD
                     NLILTKYHGLKTVFETAEFDNLTPRIQRMRLIKSADEVQKMMVAGLYADKAVHVGFDN
                     ISLDKTETDIIAQIDFAMKREGYEMSFDTMVLTGDNAANPHGIPAANKVENDALLLFD
                     LGVLVNGYASDMTRTVAVGKPDQFKKDIYNLTLEAQQAALDFIKPGVTAHEVDRAARE
                     VIEKAGYGEYFNHRLGHGIGMDVHEFPSIMEGNDMVIEEGMCFSVEPGIYIPGKVGVR
                     IEDCGVVTKDGFDLFTSTSKDLLYFD"
     gene            complement(13627..14409)
                     /locus_tag="VYO11_001486"
     CDS             complement(13627..14409)
                     /locus_tag="VYO11_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HEV1596034.1"
                     /translation="MVYTSLSSKDGNYPYQLNIAHLYGNLMNTYGDNGNILMLKYVAE
                     KLGAHVIVDIVSLHDDFDENHYDIAFFGGGQDFEQSIIADDLPAKKESIDNYIQNDGV
                     VLAICGGFQLLGQYYVEASGKRIEGLGVMGHYTLNQTNNRFIGDIKIHNEDFDETYYG
                     FENHQGRTFLSDDQKPLGQVVYGNGNNEEKVGEGVHYKNVFGSYFHGPILSRNANLAY
                     RLVTTALKKKYGQDIQLPAYEDILSQEIAEEYSDVKSKADFS"
     gene            complement(14409..15752)
                     /locus_tag="VYO11_001487"
     CDS             complement(14409..15752)
                     /locus_tag="VYO11_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HEV1596035.1"
                     /translation="MNLKTTLGLLAGRSSHFILSRLGRGSTLPGKVALQFDKDILQNL
                     AKNYEIVVVTGTNGKTLTTALTVGILKEVYGQVLTNPSGANMITGIATTFLTAKSSKT
                     GKNIAVLEIDEASLSRICDYIQPSLFVITNIFRDQMDRFGEIYTTYNMILDAIRKVPT
                     ATVLLNGDSPLFYKPTIPNPIEYFGFDLEKGPAQLAHYNTEGILCPDCQGILKYEHNT
                     YANLGTYICEGCGCKRPDLDYRLTKLVELTNNRSRFVIDGQEYGIQIGGLYNIYNALA
                     AVAIARFLGADLQLIKQGFDKSRAVFGRQETFHIGDKECTLVLIKNPVGATQAIEMIK
                     LAPYPFSLSVLLNANYADGIDTSWIWDADFEQITDMDIPEINAGGVRHSEIARRLRVT
                     GYPAEKITETSNLEQVLKTIENQDCKHAYILATYTAMLEFRELLASRQIVRKEMN"
     gene            complement(15851..17167)
                     /locus_tag="VYO11_001488"
     CDS             complement(15851..17167)
                     /locus_tag="VYO11_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000958936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HEV1596036.1"
                     /translation="MLTYDLIVIGFGKAGKTLAGKLASAGKKVALVERSKAMYGGTCI
                     NIGCIPTKTLLVAAEKDLSFEEVIATKNTITGRLNGKNYATVAGTGVDIFDAEAHFLS
                     NKVIEIQAGDEKKELTAETIVINTGAVSNVLPIPGLATSKNIFDSTGIQNLDKLPEKL
                     GILGGGNIGLEFAGLYNKLGSKVTVLDALDTFLPRAEPSIAALAKQYMEEDGIELLQN
                     IHTTEIKNDGDQVLVVTEDETYRFDALLYATGRKPNVEPLQLENTDIELTERGAIKVD
                     KHCQTNVPGVFAVGDVNGGLQFTYISLDDFRVVYSYLAGDGSYTLEDRLNVPNTMFIT
                     PALSQVGLTESQAADLKLPYAVKEIPVAAMPRGHVNGDLRGAFKAVVNTETKEILGAS
                     IFSEGSQEIINIITVAMDNKIPYTYFTKQIFTHPTLAENLNDLFAI"
     gene            17360..18586
                     /locus_tag="VYO11_001489"
     CDS             17360..18586
                     /locus_tag="VYO11_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OFA family MFS transporter"
                     /protein_id="HEV1596037.1"
                     /translation="MKSNRYIIAFAGVILHLMLGSTYAWSVYRNPIIEKTGWDQASVA
                     FAFSLAIFCLGLSAAFMGRLVEKFGPRVMGSLSAFLYAGGNILTGFAIDRQELWLLYL
                     AYGILGGLGLGSGYITPVSTIIKWFPDKRGLATGLAIMGFGFASLLTSPIAQHLIAGV
                     GLVETFYILGASYFIIMLLASQFIKRPNEQELAILSASGKEKTDSLTQGMTANQALKS
                     NRFYILWIIFFINIACGLGLISAASPMAQEMAGLSTSHAAVMVGVLGIFNGFGRLLWA
                     SLSDYIGRPLTFSILLLVNLFFSLSLWLFTDSVLFVVAMSILMTCYGAGFSLIPAYLS
                     DIFGTKELAALHGYILTAWAMAGLAGPILLAETYKMAHSYTQTLFVFLILYSIALALS
                     YYLGRSIKKESQKPLT"
     gene            18785..20344
                     /locus_tag="VYO11_001490"
     CDS             18785..20344
                     /locus_tag="VYO11_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEV1596038.1"
                     /translation="MKFNELNLSADLLAEIEKAGFVEASPIQEQTIPLALEGKDVIGQ
                     AQTGTGKTAAFGLPTLEKIRTEEATIQALVIAPTRELAVQSQEELFRFGRSKGVKVRS
                     VYGGSSIEKQIKALKSGAHIVVGTPGRLLDLIKRKALKLQNIETLILDEADEMLNMGF
                     LEDIEAIISRVPENRQTLLFSATMPDAIKRIGVQFMKAPEHVKIAAKELTTELVDQYY
                     IRVKEQEKFDTMTRLMDVAQPELAIVFGRTKRRVDELTRGLKIRGFRAEGIHGDLDQN
                     KRLRVLRDFKNGNLDVLVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KSGQSITFVAPNEMGYLQIIENLTKKRMKGLKPASVEESFQSKKQVALKKIERDFADE
                     TIRANFEKFGKDARKLAAEFTPEELAMYILSLTVQDPDSLPEVEIAREKPLPFKPSGN
                     GFGGKAKGGRGGRRGDDRRERDRRDEFKKGSRGNDRFDKEKRYRKDNKKPRNTLSEKQ
                     TGFVIRNKGDK"
BASE COUNT         5854 a         3899 c         4597 g         6162 t
ORIGIN      
        1 agtcagatag tatttttgga gccttaaatt ctgacagtct attcgtaaga ttacaaatca
       61 tactcttagc ttcagattct gacttaggat atagagttat aaatttgtta gcagtagggc
      121 tcatttccct aggggaatta atttttttta attcctctaa atttttaaca actttaaagc
      181 tacaattatt tagttgggat agtttataca caatcttaaa aatatttaca gcgtctttta
      241 tttgggagct tatgtgtatt ttccaccctt gtgcaggcac cttatctgat aaataatagt
      301 aattccaaat atcaccctgt tggaaatttt tatcacattt taaacattct ttctctaata
      361 aatccataac aaactcctaa ttattaaaat aggctagaga cacagcacta gcctattccg
      421 taagtaaagc tacttatttt atataaaata taactagcga cctgtaatta aacaagtaaa
      481 agaacaatac ttagggagac ctgtgacaat gatatcttcc tctggaagta gttctaattc
      541 aaacaatgtt tgttccatga ctgtatcctc ctgttatgat aaattccaga aagcatagag
      601 caaattcgtg gttcgtctga ctaaatttct tatctgaaca ccaccttcaa atacaaattt
      661 tagtcaaact tttatttttt ctaactttct aattatattc taccatgtgt ttttatatgt
      721 caagaatttt ctgaataaac tgtttatttt ttattttttg acatttttgc aaattgttta
      781 aaatctttca attggattca cttattactt taggacattg aaacttcttt cgccagaggt
      841 gcttatatta ctgggaagtt gaagattgaa atgtggtata ataagaggta atagagtttt
      901 ggaaagtgag agaagatgat ttcaaagaga ttagaattgg tagcttcctt tgtgtcacag
      961 ggggctattt tactagatgt gggaagtgac catgcttatc tgcctatcga gttggttgag
     1021 agaggccaaa tcaaaagcgc tattgcaggt gaggtggtgg aaggtcccta tcagtctgcg
     1081 gttaaaaatg ttgaggctca cggcctaaag gagaaaatcc aagtccgttt agccaatggc
     1141 ttggcagctt ttgaagagac tgaccaagtg tctgtcatta ccattgctgg catgggtggt
     1201 cgtttgattg ctaggatttt agaagaaggt ttggggaagt tagctaatgt agagcgtttg
     1261 atcctccagc ccaataatcg tgaagacgac ttgcgtatct ggctacagga tcatggattc
     1321 cagattgtag cagaaagcat cttagaagaa gctggaaagt tttatgagat tttggtggtg
     1381 gaagcaggac aaatgaagct atcagccagt gatgttcgct ttggtccctt cttgtccaaa
     1441 gaagtcagtc cagtatttgt ccaaaaatgg caaaaagaag ctgagaagct agagttcgcc
     1501 ctcggacaaa tcccagaaaa aaatctggaa gaacgtcaag ttctagtaga taagattcaa
     1561 gctatcaagg aggtgctcca tgttagcaag tgaagtgatc caagcttatg aagccttttg
     1621 ccctcaggaa ttttctatgg agggagacag ccgtggtctg caaattggca ctttagacaa
     1681 gggtatccaa agggtcatgg ttgccctcga tattcgtgaa gagacggtgg cagaggccat
     1741 tgaaaagggt gtggacttga ttatcgtcaa gcacgcgcct atctttcgtc ctatcaagga
     1801 cttgcttgcc agccgtccgc aaaatcagat ttacatcgac ctgattaagc atgatatcgc
     1861 agtttatgtc agccatacca atattgatat cgttgaaaat gggctcaatg actggttttg
     1921 tcagatgcta ggaatcgagg agacgactta tctgcaggaa acaggtccag aacgtggaat
     1981 tggacgtatt gggaatattc agcctcagac attttgggaa ttggcccaac aggtcaagca
     2041 agtctttgac ctagatagcc ttcgaatggt gcattatcaa gagaatgatt tgcagaagcc
     2101 tatttcaaga gtagcaattt gtggtggaag cgggcagtct ttctataagg atgctttggc
     2161 aaagggggca gatgtctata tcactggcga catctactac catactgctc aggatatgct
     2221 gtctgatggc ttgttagcat tggatccagg tcactatatc gaagtgcttt ttgtggaaaa
     2281 aatcgcagca ctccttactc aatggaaaga gaaaaaaggc tgggaactag agattttacc
     2341 tagtcaagca tcgaccaatc ctttccgtca tatctagtta gaaagtgaag acaatgaaaa
     2401 aagttgccat tattggagca ggaattgtgg gagcaacagc tgcctactac ctctcgagag
     2461 aaagtgacct agaggtgacc gtttttgacc atgagcaagg tcaagccacc aaggccgcag
     2521 caggaattat cagtccttgg ttttccaaac gccgtaataa agcctggtac aagatggcgc
     2581 gcttgggggc tgacttttat gtggatttat tagctgattt agagaaatca ggacaaaaaa
     2641 tcgactttta ccagcgttcg ggagtctttc tcttgaaaaa ggatgaatcc aagttggaag
     2701 aactttatca actggccctc cagcgcagag aagaatctcc cttgataggg caattagcca
     2761 ttctggacca agcttcagct aatgaattat tccctggttt gcagggattt gaccgcctgc
     2821 tctatgcttc tggtggagcg agagtagatg gccaactctt ggtaactcgt ctgctagaag
     2881 ccagtcatgt caagctggtc aaagaaaaag tgactctgac actcttatca tcaggctacc
     2941 agattggcga agaggtgttt gatcaggtta ttttggcaac gggagcttgg ttgggggaca
     3001 tgttagagcc tttaggttat gaagtggatg tccgtcctca aaaaggacaa ctacgagatt
     3061 atcagcttgc ccaagacatg gaagcttacc ctgttgtcat gccagaaggg gagtgggatt
     3121 tgattccctt tgcaggtggg aaattatcct tgggcgctac ccatgaaaat gacatgggat
     3181 ttgatttgac ggtagatgaa cccttgctcc aacaaatgga ggaggcggcc ttgcctcatt
     3241 acccagtttt agctagagcg acttcaaggg ctgagcgtgt gggaatccgt gcctatacca
     3301 gtgatttctc tcccttcttt gggcaggtgc cagaattggc aggtgtctat gtagccagtg
     3361 gactaggttc atcaggcctc acaactggtc ctatcattgg ttaccatcta gcccaactga
     3421 tccaagacaa ggagttgacc ttggaccctc taaattaccc aattgaaaac tatgtcaaac
     3481 gagtaaaaag cgaataatac tcaatgaaaa tcaaagaaca aactaggaaa ctagccgcgg
     3541 gttactcaaa gcactgcttt gaggttgtgt atagaactga cgaagtcagt aaccataccc
     3601 atggcaaggc gacgttgacg tggtttgaat tggattttcg aagagtataa gcattttact
     3661 gaaattttat caggtagttt aggatggcaa atgacattcc ctgtcaaaaa tggtaaaata
     3721 agaaaaaata atctgagaat cgaggaaaaa agatgcaaga aaagattttg gtaactggtg
     3781 gtgccggttt tattggaacc cacactgtta ttgaattgat ccaagcaggc catcaagttg
     3841 ttgtggtgga taatcttgtc aatagcaatc gtaagagttt agaagttgtt gaaagaatca
     3901 caggagttga gattcctttc tatgaggcag atattcgtga cacagttacc ctcagagata
     3961 ttttcaagca ggaagaaccg actggtgtca ttcactttgc tggtttgaag gctgttggcg
     4021 aatcaacacg tatccctctt gcctactatg acaacaatat cgctggaact gtcagccttt
     4081 tgaaagccat ggaagaaaac aactgtaaaa acatcatctt cagttcttct gcgacagttt
     4141 acggggatcc gcacacagtg cccatcttgg aagatttccc actttcagtg accaacccat
     4201 acggtcgtac caagctcatg ctagaggaaa ttttgaccga tatttacaaa gcagactcag
     4261 aatggaatgt tgtcttgctt cgttacttta acccaatcgg agcccatgag agtggtgatt
     4321 tgggagaaaa tccaaacggt attccaaaca atctcttgcc atatgtgact caagtagccg
     4381 ttggaaaatt agagcaagtg caagtgtttg gagacgatta cgatacggaa gatggaacag
     4441 gtgttcgtga ctatatccac gttgtcgatt tggctaaggg tcacgttgca gctttgaaaa
     4501 aaatccaaaa aggttcagga ctaaacgttt ataaccttgg aactggtaaa ggttactcag
     4561 ttcttgaaat tatccaaaac atggaaaaag cggtgggacg tcctattcct taccgcatcg
     4621 tagaacgtcg cccaggtgat atcgctgcct gctactcaga cccagcaaaa gctaaagcag
     4681 aactcggttg ggaagcagaa ctcgacatca cccaaatgtg tgaagacgca tggcgttggc
     4741 aaagcaagca tccaaatgga tttgaagact aagatgatga tttcaatcat cgtcccttgt
     4801 ttaaacgaag aggaagtact tcctcttttt tatcaggctc tggaagcttt acttccagat
     4861 ttggaaacag aaatcgagta tgtctttgtc gatgatggat caagtgatgg gaccttggaa
     4921 ctcttaaagg cctatcggga gcaaaatccg gcagtccatt atatttcttt ctctcgaaat
     4981 tttggcaaag aagcagccct ttatgcaggc ttgcaatatg cgacaggaga tttggtggtg
     5041 gtgatggatg cagacctcca agatcctcct agtatgttgt ttgagatgaa aaatgtacta
     5101 gacaaaaatg tagacttgga ctgcgttggg acacggagaa ctagtcggga gggagaaccc
     5161 ttctttcgca gtttctgtgc tgttctcttt tatcgcctca tgcaaaaaat cagcccagta
     5221 gctctgccgt cgggtgtccg tgattttcgt atgatgagaa ggtctgtggt cgatgccatt
     5281 ttaagcttga ctgagtccaa tcgtttttct aagggactct ttgcctgggt cggctttaaa
     5341 acccactatc tggactatcc aaatgtcgaa aggcaggctg gcaagaccag ttggagtttt
     5401 aggcaactct ttttttactc cattgaaggg attgttaatt tttcagattt ccctttgact
     5461 atagcctttg tagctggtct cctatcttgt tttctttctc tgctgatgac cttttttgtt
     5521 gtggttcgga ccctcatttt gggcaatccg acatctggtt ggacctctct gatggctgtt
     5581 attctctttc ttggaggcat tcaactcttg accattggaa ttctcggtaa gtatatcagt
     5641 aagatttatt tagagactaa aaaaagacca ctttatctta tcaaagaaaa aagtgacctt
     5701 cctgatttta cagaaaaaat aaagtgaaaa gactataatt ttacatggaa atgtgctaaa
     5761 ctagagggag tggattatcg ccattgattt aggcttcctg gtttccaatc agggcgcgag
     5821 ttgggcaatt tttaacagcc tctaagacat cctgactagg agaaatttct ttttccagtt
     5881 ggtcagggtc atcgtaaaaa cgcacgattc cattatcgtg gtaatcaaat aaatcagaat
     5941 aagtttggca aagtccacag gcgatacatc gttcaggtat aagtgtgatt ttcatgttca
     6001 tatttatatt gtaataagaa aagtaaaaaa aaacaaggag taaggtatgg caaaagaacc
     6061 gtggcaagaa gatatctatg atcaagaaga atcaagagca gagcgtcggc atcgaaacca
     6121 cggaggggct gataggatgg ctaatcgtat tttgacgatc ctagctagta ttttctttgt
     6181 aattgtggtg gtgatggtca tcgttctcat ctatctatca tcggggggaa gtaatcgcac
     6241 agcagcctta aaagactttc atgattctga tgcaagtgta gtacaaatct catcttcaag
     6301 cagttctcat cctgagcaga gttcagagcc agaatctact tctagtagtt cagaagaagc
     6361 tgctaatcct gaaggaacga ttaaagttct cgcaggagaa ggggaagcag ctattgccgc
     6421 tcgtgcagga atctccattg ctcagttaga ggccttgaat cctgggcaca tggctacagg
     6481 atcttggttt gctaatccag gtgatgttat aaaaataaaa taggagccga tatgaaaaca
     6541 attcaaattg ctattgatgg tcctgcttcc agcggtaaga gtacggtcgc aaagattatt
     6601 gctaaggatt ttggattcac ctaccttgat acaggagcta tgtatcgtgc agcgacctat
     6661 atggctctta agaaccaatt aggagttgaa gaagtcgaag ctcttctagc cttgttggac
     6721 cagcatccaa tcagctttgg acgttcagaa actggagacc agcttgtttt tgtaggagat
     6781 gtggatatta cccatcctat ccgtgaaaat gaagtgacca atcatgtttc tgctattgca
     6841 gcaattcctg aagtgcgtga gaaactggtt tctctccaac aagaaattgc ccagcaaggc
     6901 gggattgtca tggatggtcg cgatattgga actgttgtat tgccgcaagc agaattgaaa
     6961 attttcctag tagcttctgt tgatgagaga gcagagcgtc gttacaagga aaatattgcc
     7021 aagggaattg aaacagacct tgaaacccta aaaaaggaaa ttgctgcgcg tgactacaag
     7081 gatagtcatc gtgagacttc tcctctcaaa caagcagagg atgctgtcta ccttgataca
     7141 actggtttga acattcaaga agtagttgaa aaaatcaaag cagaagctga aaaaagaatg
     7201 taaatgtaga aaagccgata gattgatatc ggtttttttc taaatttgtc aaaatgctga
     7261 ttttagggta taatagttgc tgttcgagaa attttgattt tcaaagaata gtgaatgatg
     7321 ataaggagaa accatgaaca atttaccaaa ttgtccaaaa tgtaactcag agtatgtcta
     7381 cgaagacggt gccctactgg tttgcccaga gtgtgctcat gagtggaatc ctgctgaagt
     7441 tgcagaagta gaagaaggtc ttgtcgctat cgatgccaac ggaaataaat tgactgatgg
     7501 tgatacagta actctcatca aggacttgaa agtaaaaggt gcgccaaaag atttgaaaca
     7561 agggacgcgc gtgaaaaata tccgcatcgt agaaggcgac cacaatatcg actgtaagat
     7621 tgatggtttt ggtgccatga aacttaaatc agagtttgtg aggaagattt aagcatgtca
     7681 aaacactata aacttgtatt ttatagccgt atcttcttgt ttctagcggc ttttacggga
     7741 gtttatcttg aaattactag gcatggtggt tttgggatgc ttctctatta cacggttctg
     7801 tccaacctct tggtaactat ttttaccctt tatcttctaa aggttatgag ccgtgtaggt
     7861 gaaaattggc aaaggccaag tctcttgcgc ttaaaaggtg gggtcaccat gagtatcatg
     7921 attacctgtg tgatttacca tttcctcttg gcgcccattg cgactaattt ctatacccta
     7981 gaaaatttcc tttgccacta tatcgttccc atctggtttt tagcggatac cctctttttt
     8041 gacaaacagg gtcaatacaa gatttgggat ccagcagtgt ggaccatttt accctttctg
     8101 tatatgatgt ttgctctttt taatggcttg gttctaaaac tcaatattcc aaatgccaag
     8161 gataatcctt tcccttactt ctttttgaat gtgaacaagg gttggaatgt tgtgtttaag
     8221 tggtgtctga ttatctttgt tgcctatatg gtagcaggat ttattttcta ctttatcaag
     8281 caaatcaaga gaaagtcatc ctaatactct tcgaaaatct cttcaaacca cgtcagtttc
     8341 catctgcaac ctcaaaacac tgttttgagc agcctgcggc tagcttccta gtttgctctt
     8401 tgattttcat tgagtataag atacaaggga ttcattttcg aatttaagaa ggagtctaca
     8461 aaccaatgag gcttcttctt ttcttgctta tttgataact atcaaaaaag tagaagatta
     8521 agagaaatat agaaagagat ttcatgaaac aatttttaga acgggccagc attttggctc
     8581 tctccctcgt tttgattacc tccttttcca tttcgagtgc cctaccagcc atgtttgact
     8641 attatcaggg ttattctaag gaacaaattg agctcttggt gagcttgcct tcctttggaa
     8701 tcatgatgat gttactgcta aatggtttct tagaaaaaat atttcctgag cgcttacaga
     8761 ttagtttggg cttgctgatt ttatcattga gcggtacagc tcccttctgg taccaagcct
     8821 atccctttgt ctttggaaca cggcttctct ttggtttggg tcttgggatg atcaatgcca
     8881 aggccatttc tattatcagt gaacgctacc aaggaaaaag gcgaattcag atgttagggc
     8941 tacgcgcttc tgcagaggtc gttggagctt ctctcattac cttggccgtc ggtcagttgt
     9001 tggcctttgg ttggacagct atctttctag cctatagtgc tggatttttg gtgctgcccc
     9061 tttatctgct ctttgtccct tatggaaaat caaagaaaga agtcaagaaa agagcgaagg
     9121 aagcaagtcg tttaactcga gaaatgaaag gcttgatttt taccttagct atcgaagcgg
     9181 cagttgtagt ttgtaccaat acagctatta ccatccgtat tccaagtttg atggtggaaa
     9241 gaggattggg ggatgcccag ttatctagtt ttgttcttag tatcatgcag ttgatcggga
     9301 ttgtggctgg ggtgagtttt tctttcttga tttctatctt taaagagaaa ctgctcctct
     9361 ggtctggtat tacctttggc ttggggcaaa tcgtgattgc cttgtcttca tccttgtggg
     9421 tggtagtagc aggaagtgtt ctggctggat ttgcctatag tgtagtcttg acgacggtct
     9481 ttcaacttgt ctctgaacga attccagcta aactcctcaa tcaagcaact tcatttgctg
     9541 tattaggctg tagtttcgga gcctttacga ccccattcgt tctaggtgca attggcttac
     9601 taactcacaa tgggatgttg gtctttagta tcttaggagg ttggttgatt gtaatctcta
     9661 tctttgtcat gtacctactt cagaagagag cttaggattg attcctaagt ttttcttttg
     9721 atactcaatg aaaatcaaag agcaaactat agttgattga gtttggaata gtacgctgta
     9781 gctgctaaaa tatttctaga aattaatttg actttcctaa tagagttgtt catatcttat
     9841 ttcaatctac tatagaaagc tagccgcagg ttgctcaaaa tagtgttttg aggttgcaga
     9901 tggaaactga cgtggtttga agagattttc gaagagtatg agatttttat acccatacaa
     9961 tatttgtttt aggtccttgt ttacagacta atttcttgat aaaatagagg ctatgacgag
    10021 atataaagca actatttcct atgatggtta tgcctttgct ggctttcagc gccagcctca
    10081 tgcgcgtagc gttcaggaag aaattgaaaa aaccttgacc agattaaata aagggcaagc
    10141 cattactgtt cacggtgctg gtaggacaga tagtggggtt catgccctgg gacaggtcat
    10201 tcattttgac ctgccttatc agatggatga ggagaaactc cgttttgcct tggataccca
    10261 gtctcctgaa gatattgatg tgatttcgat tgagcttgtg gcagatgatt ttcattgccg
    10321 ttatgccaag catagcaaga cctatgagtt tattgtggat agaggacgtc ccaaaaatcc
    10381 gatgcgccgt cactatgcca cccactttcc ctacccactc gatgtggaac gaatgcagat
    10441 tgcaatcaaa aagctagagg gaacccatga ttttaccggt tttacagcct ctgggactag
    10501 tgtagaggat aaggttcgca ccatcacaga agctagttta atagtcgatg agacaggaca
    10561 atttttgacc tttacctttt caggaaatgg tttcttgtat aaacagattc gcaatatagt
    10621 ggggactctt ctcaaaatcg gtaacaaccg catgccagta gagcagattg atctcatctt
    10681 ggagaagaag gacaggcaac ttgcaggtcc cactgcagca ccaaatggtt tgtatttaaa
    10741 ggagattcgt tatgaagaat aatcgtattt tagcactttc tggaaatgat atttttagtg
    10801 gtggtggact gtcggctgat ttggctacct ataccttgaa cgacttgcat gggtttgtag
    10861 cagtgacttg tttgacagcc ttgacagaaa aaggatttga agtctttcca actgatgata
    10921 ccatttttca acatgaatta gatagcttgc gtgatgtgga atttggggga attaagattg
    10981 gtcttctccc tactgtcagt gtggctgaga aggccttgga ctttatcaaa caacgcccag
    11041 gagtacctgt ggtgttggat cctgtcttgg tctgcaagga aacgcatgat gtagctgtca
    11101 gtgagctctg ccaagagttg attcgctttt tcccttatgt cagtgtgatt acgcctaatc
    11161 tcccagaagc agaattatta tccggtcagg aaattaaaac cttggaagac atgaaaactg
    11221 cagcgcagaa attgcatgat ttaggagctc cagcagtcat tatcaaggga ggcaatcgtc
    11281 ttagtcagga caaggctgtg gatgtctttt atgatggaca gacctttact atcctagaaa
    11341 atccagttat ccaaggccaa aatgctggtg caggttgtac ctttgcctct agcattgcca
    11401 gtcacttggt taaaggtgat aaacttttgc cagcagtaga aagctctaag gctttcgttt
    11461 atcgtgctat tgcacaagca gatcagtatg gagtaagaca atatgaagca aacaaaaaca
    11521 actaaaatcg cccttgtatc cctattaacc gccctttctg tggttctagg ttatttctta
    11581 aaaatcccaa cacctacagg aattctaact cttttagatg ctggtgtctt ctttgcggcc
    11641 ttttactttg gtagtcgtga aggagcggta gtcggaggac tagcaagttt cttgattgac
    11701 ctcttatcag gctaccctca gtggatgttc tttagcttgg tcaaccatgg cttgcaggga
    11761 tttttcgcag gatttaaagg aaaaagtcag tggttaggcc ttattttagc aactattgcc
    11821 atggtaggag gctacgcctt gggttcgact ttgatgaatg gctgggcagc agccctccca
    11881 gaaattctac caaatttcat gcaaaatatg gtagggatga ttgtaggatt tattcttagt
    11941 caaagtatca agaagattaa gtaatactct tcgaaaatct cttcaaacca cgtcagtttc
    12001 catctgcaac ctcaaaacac tgttttgagc agcctgcggc tagctttcta gtctgatttt
    12061 cattgagcat aaagaggttg agtaaaaagt ctttcaaata agaaaaacgc atagtatcag
    12121 gtgttgaatg aacacctgat actatgcgtt ttattgtggg aagattttcc tcattttcta
    12181 gtgaaattga actttttcta acatcttttg atagatgact tcttaatcaa ttctcatttc
    12241 cattgttgtt tcttggggtt tcatcccttg tctttgataa aagcggagag caccctcgtt
    12301 atcattccag acacttaggg ttagattact gcagccaatt tctttagcat aatagcagaa
    12361 aaatgacaat aaaatagccc ctagatattt tgaaaggaaa gcataggggc tatatagttt
    12421 aatcaaaata aagcaaatct ttgctggtgc ttgtaaagag gtcgaagcca tccttggtaa
    12481 caacaccgca gtcttcaata cgaacaccga ctttaccagg gatatagata cctggttcaa
    12541 cagagaagca catgccttct tcgatgacca tgtcgtttcc ttccatgata gatgggaatt
    12601 catggacatc cataccgata ccatgcccga gacggtggtt gaagtactca ccataaccag
    12661 ctttttcgat gacctcacgg gcagcgcggt ccacttcatg agcagtcaca cctggcttga
    12721 taaagtcaag agcagcttgt tgggcttcaa gagtcaagtt gtaaatatct ttcttgaatt
    12781 ggtctggttt gccgacagcg actgtacgag tcatatctga cgcatagcca ttgaccagaa
    12841 cacccaggtc aaagaggaga agagcatcat tttcaacctt attagctgct ggaatgccgt
    12901 gtggattcgc agcattatca ccagtcaaga ccatggtatc aaagctcatt tcgtaacctt
    12961 cacgtttcat ggcaaagtca atttgtgcga tgatatctgt ctcagtctta tcaagagaaa
    13021 tattgtcaaa accaacatga acagccttgt cagcataaag acctgcaacc atcatttttt
    13081 gcacttcatc agctgatttg atgaggcgca tgcgttggat acgaggagtg aggttgtcaa
    13141 actcagcagt ctcaaaaact gttttcaaac catggtattt ggtcaagatg agattgtcaa
    13201 actcaacagc gacacgtttg aagtcaagtt gtggaagagc atgtttgatt ttttgccatg
    13261 gattttcaga atcgacatag cccactactg ggaaggaaac ggtgctactt gcacgttcta
    13321 cttcaagagc tgggacaaag aggagaggtt cctgatctgc taggacaaag aggaacattt
    13381 ggcgttcatg gggatcactg taaaaaccag tgaggtaatt gattgtgacg gggtcagata
    13441 cgacagcgac gtctagtttt tctgattcaa gatatgttag gatttgttgt aatttagaca
    13501 tatgctacct tctttctacc cctctatttt ggcaaaaaat gagagaaaat gcaagggaga
    13561 agggtaaaag aaaagacaaa aaactccgac aagataacgg agttctttga tatcattttc
    13621 ctttgtttaa gaaaagtcag ccttgctttt gacgtcactg tactcttcag cgatttcttg
    13681 gctgagaatg tcctcatagg cagggagttg gatgtcctga ccatatttct tcttgagggc
    13741 agtagtaact aggcgataag ccagattggc attacgagag aggataggcc cgtggaagta
    13801 ggaaccaaag acattcttat aatgaacccc ttcaccgacc ttttcttcgt tgtttccatt
    13861 tccatagaca acctgtccca gcggtttttg gtcatcagag aggaaggtac gaccttggtg
    13921 attttcaaat ccatagtagg tttcatcgaa atcttcattg tgaatcttga tgtcaccgat
    13981 aaaacggtta ttggtctggt tgagcgtgta gtgtcccatg acccctagcc cttcgatacg
    14041 ttttcctgaa gcttcaacat aatattgacc caatagttgg aaaccaccgc agatagccag
    14101 aactacaccg tcgttttgga tgtagttgtc aatgctctct tttttagcag gtaggtcgtc
    14161 tgcaatgata ctttgttcaa agtcttgacc accaccgaaa aaggcgatgt cgtagtgatt
    14221 ttcatcaaag tcatcatgga gagaaacgat gtcaacgatc acatgggctc ccagtttttc
    14281 agccacatac ttgagcatga ggatgtttcc attgtccccg taggtattca tgagatttcc
    14341 gtagaggtgg gcaatgttga gctgataggg gtaattgcca tcttttgagg aaagtgaagt
    14401 ataaaccatt agttcatctc ctttctaaca atctgacgac tagccagcag ttcacgaaat
    14461 tccagcatgg cagtataagt tgccagaata taggcatgct tgcagtcttg attctcaatg
    14521 gtcttgagaa cttgctccag attactcgtt tcagtgattt tctcagctgg atagccagtc
    14581 actcggaggc gacgagcgat ttcagaatga cgaacaccgc cagcgttgat ttcaggaatg
    14641 tccatgtcag tgatttgttc aaagtctgca tcccagatcc agctagtgtc aattccatct
    14701 gcatagttgg cattaaggag gacagatagg ctaaatggat aaggtgctag tttgatcatt
    14761 tcgatagctt gggttgcacc gactggattt ttaatcaaga caagggtaca ttccttgtca
    14821 ccgatatgaa aggtttcttg gcgtccaaag acagcacggc tcttgtcaaa tccctgtttg
    14881 atgagttgca aatcggcacc taggaaacgg gcgatggcca cagcagctag ggcgttatag
    14941 atattataga gcccgccgat ttggataccg tattcttggc cgtctatgac aaagcgagag
    15001 cgattgttgg tcaactcaac cagttttgtc aaacgatagt cgagatcagg acgtttacat
    15061 ccacaacctt cacagatata ggtacccaag tttgcatagg tattatgctc atatttgagg
    15121 atgccttggc agtcaggaca gagaatccct tcggtattgt agtgagccag ttgggctggt
    15181 cctttttcca agtcaaaacc aaaatactct atagggtttg gaatagttgg cttgtagaaa
    15241 agtggactgt ctccgttaag gagaacagta gcagttggaa ctttccgaat ggcatccaat
    15301 atcatgttat aggtagtata gatttcaccg aaacggtcca tctggtcacg gaagatatta
    15361 gtaatgacaa aaagactagg ctggatatag tcacagatac gagatagact ggcttcgtca
    15421 atttcgagga cggcaatatt ttttccagtt ttagaagatt tggctgttag gaaggttgtt
    15481 gcaatccctg taatcatgtt ggcaccgctt ggattggtta gaacttgacc atagacctct
    15541 tttaaaatgc cgacagtgag ggcagttgtc agggtttttc catttgttcc agtgacaacg
    15601 acaatctcgt agttcttagc taggttttgt aaaatatctt tatcaaattg aagggcgact
    15661 ttacctggga gcgtacttcc acggccaaga cggcttaaaa tgaagtggga agaacgccca
    15721 gcaagaaggc ccaaagtagt ttttaagttc atgtttctat tatatcataa aagaggagaa
    15781 agacagattt gagattccgc agaagtaaaa acagcccaaa gagggctgtt cgatacgatt
    15841 aaatctcaac ttaaatcgca aacaagtcat tcaagttctc agccaaggtt gggtgagtga
    15901 agatttgttt tgtgaagtaa gtgtaaggaa tcttgttgtc catagcaaca gtgatgatgt
    15961 tgatgatttc ttgagaacct tctgagaaga tgcttgcacc aagaatttct tttgtttcag
    16021 tattaacaac agctttgaaa gctccgcgaa ggtctccatt tacgtgacca cgaggcatgg
    16081 ctgcaacagg gatttctttc actgcgtatg gaagtttcaa atcagctgct tggctttcag
    16141 tcaaaccaac ttgtgaaagt gcaggtgtga tgaacatagt atttggcaca ttgagacggt
    16201 cttcaagtgt gtagctgcca tctccagcaa ggtagctgta aacaacacgg aagtcatcaa
    16261 gtgaaatgta agtaaattga aggccaccgt tgacatctcc aactgcaaag acaccaggaa
    16321 cgtttgtttg acagtgtttg tctactttaa tagcaccacg ttcagttagt tcaatatctg
    16381 tattttcaag ttgaagtggt tctacatttg gtttgcgtcc agttgcgtag agaagggcgt
    16441 cgaaacggta agtttcgtct tcagttacga caagcacttg gtcaccatcg tttttgattt
    16501 cagtagtatg gatattttga agcaattcaa tgccatcttc ttccatgtat tgtttagcaa
    16561 gagctgcgat ggaaggttct gcacgaggaa ggaaagtatc caaggcatct aggactgtga
    16621 ccttgcttcc aagtttgttg taaaggccgg caaattcaag accgatattt ccgccaccaa
    16681 ggattccaag tttttcaggt aatttgtcca agttttggat acctgttgag tcaaagatgt
    16741 ttttgcttgt agcaagtcca gggattggca agacgtttga aacagcacca gtgttgatga
    16801 cgattgtttc agcagtcagt tctttctttt catcaccagc ttggatttcg atgactttat
    16861 ttgaaaggaa gtgagcttcc gcatcaaaga tatctacgcc tgtaccagca acagtcgcat
    16921 agtttttacc gttgaggcga ccagtgatcg tgtttttagt agcaatcact tcttcaaaag
    16981 acaagtcctt ttcagcagca actagcaagg ttttagttgg gatacaacca atgttgatac
    17041 aagttccacc gtacatagcc ttgctgcgtt caacgagggc aacttttttg ccagctgaag
    17101 ccaatttacc tgctagtgtt ttaccagctt taccaaatcc aataacaatt aaatcgtatg
    17161 ttaacattta tcttcctcct attcgaattt cattctagca caagaaaaaa acttttgcac
    17221 aattctgcta cggaaaagac agaaaaagat aaaaacgctt tccagacaaa aaactagtaa
    17281 ttttttgaca agcttgataa actaaaatcc tatctatttt tatataagat agaataaatg
    17341 ttcgaaaata gggggtttta tgaaatcgaa tcgttatatt attgcctttg ctggggtcat
    17401 tttacactta atgctgggtt cgacttatgc ttggagtgtt tatcgtaacc ctattattga
    17461 aaaaacggga tgggatcagg cttctgttgc ctttgccttt agtctagcaa tcttttgttt
    17521 gggcttatcg gctgcattta tggggcgttt ggtagaaaaa tttggtccga gagtcatggg
    17581 gagtctatct gcttttctat acgcaggtgg aaatatctta acaggatttg caatagaccg
    17641 tcaggaactg tggttgttgt atctagctta tggcatttta ggtgggcttg gtttgggatc
    17701 aggctatatt acccctgtgt caacgattat aaaatggttt cctgataaac gtggtctcgc
    17761 aacaggttta gcgattatgg ggtttggttt tgcttcttta ttgactagtc ccatagcgca
    17821 acatctcatc gcaggggtag ggcttgtaga aactttttat attttaggtg caagttactt
    17881 tattatcatg ctcctagctt cacaattcat taagcgtcca aatgagcaag agcttgcaat
    17941 tttatctgct tcagggaaag aaaaaacaga ctctctgacg caagggatga ctgcaaatca
    18001 ggctctaaaa agcaatcggt tttatatact ttggattatt ttctttatca acatagcttg
    18061 tggtttaggc ttaatttcag cggcatcgcc aatggcacag gagatggctg gcttgtctac
    18121 aagtcatgca gcagtaatgg tgggcgtttt agggattttc aatggatttg gtcgcttgct
    18181 ctgggcgagc ttatctgact atatcggtcg ccctctaacc tttagtatat tactgcttgt
    18241 taatcttttc ttttctctct cactttggct ctttacagat tccgttttat ttgtagtcgc
    18301 tatgtctatt ttgatgactt gctatggagc tggtttttca ttgatcccag cttatctcag
    18361 tgatattttt ggaaccaagg aattggccgc tctgcatgga tatattttaa cagcttgggc
    18421 aatggctggt ttagcgggac ctattttatt agcagagact tataaaatgg ctcattcgta
    18481 cacacaaacc ttgttcgttt ttctcatttt atacagtatc gccttggctt tgtcttatta
    18541 tctaggtcgt tcaatcaaaa aagaaagtca aaaaccgctt acatgatttt ctgtagaaat
    18601 ggggctatct tttgctctgg tcttgtgtta tactagatag gttgcaaaga aaacagtact
    18661 tttcttttgt ggaaaagaag caacacgatt ttatatctag ttatatgaaa atacgtcata
    18721 aaaagaaaag tataaactaa gccctatagg gtggcttcgc accaccttta gaaagaagaa
    18781 taacgtgaaa tttaatgaat taaacttgtc tgctgatttg ctggcagaaa ttgaaaaagc
    18841 tggttttgta gaagctagtc ctatccaaga acaaactatt cctttggccc ttgaaggcaa
    18901 ggatgttatc ggtcaagctc agactggtac aggaaaaact gcagcctttg gcttgcctac
    18961 ccttgaaaaa atccgtacag aagaagcgac tatccaagcc ttggtcatcg ctccaactcg
    19021 tgaactagct gtccaaagtc aagaagaact cttccgcttt ggtcgtagta agggagtcaa
    19081 agtccgttca gtatatggcg gatcaagcat tgaaaaacaa attaaggctc ttaaatctgg
    19141 tgcccatatc gtggtgggaa ctccaggtcg cctcttggac ttgattaaac gcaaggcctt
    19201 gaaattacaa aacattgaaa cccttatcct tgacgaagcg gatgaaatgc ttaacatggg
    19261 cttccttgaa gacatcgaag ccattatttc ccgtgtacct gagaaccgtc aaactttgct
    19321 tttctcagca actatgccag atgccatcaa acgtatcggt gttcagttta tgaaagcccc
    19381 tgaacatgtc aagattgcag ctaaggaatt gacaacagaa ttggttgacc agtactatat
    19441 ccgtgttaag gaacaagaaa aatttgacac catgactcgt ctcatggatg tggcacaacc
    19501 agaactcgct attgtatttg gtcgtaccaa acgccgtgtg gatgaattga ctcgtggttt
    19561 gaaaattcgt ggcttccgtg cagaaggaat tcatggcgac ctagaccaaa acaaacgtct
    19621 tcgtgtcctt cgtgacttta aaaatggcaa tcttgatgtt ttggttgcga cagacgttgc
    19681 agcgcgtggt ttggatattt caggtgtgac ccatgtctac aactacgata ttccacaaga
    19741 tcctgagagt tatgttcacc gtatcggtcg tacaggtcgt gctggtaagt caggtcaatc
    19801 tattactttt gttgctccaa acgaaatggg ttaccttcaa atcattgaaa acttgactaa
    19861 gaaacgcatg aaaggtctca aacctgcaag tgtagaagaa tccttccaat caaaaaaaca
    19921 ggtagctctc aagaaaatcg aacgtgattt tgcagatgaa accattcgtg ccaactttga
    19981 gaaatttggt aaggatgctc gcaaattggc tgctgagttt actccagaag aattggcaat
    20041 gtatatcttg agtctgacag tccaagaccc agatagcctt ccagaagtgg agattgcacg
    20101 tgaaaaacca ctaccgttta aaccatcagg taatggtttc ggtggtaaag ctaagggagg
    20161 tcgtggaggc cgtcgtgggg acgaccgtcg agagcgtgat cgccgtgatg agttcaaaaa
    20221 aggaagtcgt ggcaacgatc gttttgataa ggaaaaacgt taccgtaagg ataataaaaa
    20281 accacgcaat actttaagcg aaaagcaaac aggctttgtt attcgtaaca aaggcgataa
    20341 ataagaaaaa gcggttcaaa atgaatcgct tttttatata aggagaccga atgtgaaaag
    20401 acaaataaaa ttattatatt atcttttata atgttatgat atacaaaaat aggcaacttg
    20461 tcaatagaaa aggaacaatt taattaaaaa tattctggtt tttaattaaa tt
//
LOCUS       DAVLXH010000038        19775 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00028199
            SAMN33607166-rid17955573.denovo.038, whole genome shotgun sequence.
ACCESSION   DAVLXH010000038 DAVLXH010000000
VERSION     DAVLXH010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607166
            Sequence Read Archive: SRR23725544
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 19775)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19775)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721421.1
            Genome Coverage       :: 115x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:42:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,210
            CDSs (total)                      :: 2,161
            Genes (coding)                    :: 2,023
            CDSs (with protein)               :: 2,023
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 73 of 138
            Pseudo Genes (incomplete)         :: 60 of 138
            Pseudo Genes (internal stop)      :: 40 of 138
            Pseudo Genes (multiple problems)  :: 31 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19775
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607166-rid17955573.denovo.038"
                     /strain="AUSMDU00028199"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1349"
     gene            407..787
                     /locus_tag="VYO11_001491"
     CDS             407..787
                     /locus_tag="VYO11_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0115 family bacteriocin-like peptide"
                     /protein_id="HEV1596039.1"
                     /translation="MELVLPNNYVVIDEEEMMYLDGGGVGCNWWNSRGSFATVLDVGL
                     AIYSGGATIYSAYAIKKAISANRGAITRTLRSLIIKHVGSAAGHLVNTALNVALTVTG
                     FSLGGAIAYGADWADGSLDGYIFA"
     gene            complement(1204..2052)
                     /locus_tag="VYO11_001492"
     CDS             complement(1204..2052)
                     /locus_tag="VYO11_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001268160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1596040.1"
                     /translation="MRYDFGKVYKEIRESKGLTQEEVCGGVLSRTSLSKIESGKTTPK
                     YENMEFLLRQINMSFEEFEYICQLYQPSQRTEIMQTYLNMRSIIGTSDLVNLFQKCQD
                     YLKTHHDLPIEEIRDMLEVVIYIRQHGAGELSDHAEQVVKKLWRKIEKQDTWYESDLK
                     ILNTILFSFPIEYLHLITGKILQRLEVYKNYQHLYDLRIAILLNLSTLYLYNQDKNMC
                     KQICYTLLEDAKNKKSYDRLAICYVRIGICTDDSKLIQKGFSLLELTEETSMLSHLKK
                     EVETHY"
     gene            2518..2856
                     /locus_tag="VYO11_001493"
     CDS             2518..2856
                     /locus_tag="VYO11_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase C39"
                     /protein_id="HEV1596041.1"
                     /translation="MLKKYPCTIQHDQSDCAAAVVSTVLLSYKKELSIMKIREIIGTD
                     MYGTTVSGIVSGLNKLNFTVKAVRVALEDLTPKLTFPAILQVKNDLGQNHFVVLHSIK
                     EKIKGTRITK"
     gene            2882..3328
                     /locus_tag="VYO11_001494"
     CDS             2882..3328
                     /locus_tag="VYO11_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1596042.1"
                     /translation="MMYLDGGGYLSKSACQGICAALAMSPGTFIALTGAAVLTKKLIN
                     YIKVGGLGGWLIGAAAGVLALIFLIKICVDTTIKFLFIRLFDTSTLMKRRIFFLFALD
                     VIAYLFLGYLLVIQKAGYLFSVLLLFSNFSVPFIKAKEYELFKNSK"
     gene            4464..4967
                     /locus_tag="VYO11_001495"
     CDS             4464..4967
                     /locus_tag="VYO11_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1596043.1"
                     /translation="MKLLDCILDYQERFNGKTCQVSTNYKYLEIFKVNFCLTDLHHLF
                     GLHKITRDYASQTKPAIQAGVFILEDFRNILLYNDVIERISLYEFIGDIFYFKITSCC
                     IVAKDLSKSTMKLDVIFFEDKNKRSAVLGLRRDKSGVFKPVTLHFTSAKKYAKVRKTD
                     VKEMKWL"
     gene            5253..7106
                     /gene="pspA"
                     /locus_tag="VYO11_001496"
     CDS             5253..7106
                     /gene="pspA"
                     /locus_tag="VYO11_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal surface protein A"
                     /protein_id="HEV1596044.1"
                     /translation="MNKKKMILTSLASVAILGAGFVTSQPTVVRAEEAPVASQSKAEK
                     DYDAAVKKYKAAEEDLKKAEAAQRKYDEDQKKTEEKAKETEEASKRQQAANLKYQLKL
                     REYLKYIQEKNKEKIAKAEKEMNEAKQEEDKEKANLNKVLAKVIPSDRELEKTRQEAE
                     KAKKNIPELKKKVEEAKQKVDAAKQKVDAEHAKEVAPQAKIAELENQVHRLEQDLKDI
                     NESDSEDYVKEGLRAPLQSELDTKKAKLLKLEELSGKIEELDAEIAELEVQLKDAEGN
                     NNVEAYFKEGLEKTTAEKKAELEKAEADLKKAVDEPETPAPAPAPAPAPEAPAPAPAP
                     APKPAPAPKPAPAPKPAPAPKPAPAPKPEKPAEKPAPAPKPETPKTGWKQENGMWYFY
                     NTDGSMATGWLQNNGSWYYLNANGAMATGWAKVNGLWYYLNSNGAMATGWLQYNDSWY
                     YLNTNGAMATGWLEYNGSWYYLNTNGAMATGWLEYNGSWYYLNANGAMATGWLEYNGS
                     WYYLNANGDMATGWAKVNGSWYYLNANGAMATGWAKVNGSWYYLNANGSMATGWVKDG
                     DTWYYLEASGAMKASQWFKVSDKWYYVNGLGALAVNTTVDGYKVNANGEWV"
     gene            7507..8628
                     /gene="mnmA"
                     /locus_tag="VYO11_001497"
     CDS             7507..8628
                     /gene="mnmA"
                     /locus_tag="VYO11_001497"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HEV1596045.1"
                     /translation="MSDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVVAVADQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAMTLGADYVATGHYARVARDEDGTVHMLRGVDNGKDQTYFLSQLS
                     QEQLQKTMFPLGHLEKPEVRRLAEEAGLSTAKKKDSTGICFIGEKNFKNFLSNYLPAQ
                     PGRMMTVDGRDMGEHAGLMYYTIGQRGGLGIGGQHGGDNAPWFVVGKDLSKNILYVGQ
                     GFYHDSLMSTSLEASQVHFTCDMPEEFTLECTAKFRYRQPDSKVTVHVKGDKAEVIFA
                     EPQRAITPGQAVVFYDGEECLGGGLIDNAYRDGQVCQYI"
     gene            8769..9224
                     /locus_tag="VYO11_001498"
     CDS             8769..9224
                     /locus_tag="VYO11_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEV1596046.1"
                     /translation="MTQQDFRTKVDNTVFGVRATALIVQNHKLLVTKDKGKYYTIGGA
                     IQVNEKTEDAVVREVKEELGVKAQAGQLAFVVENRFEQDGVSYHNIEFHYLVDLLEDA
                     PLTMQEDEKRQPCEWIDLDKFEDIQLVPAFLKTALPDWEGQLRHIHREE"
     gene            9234..11147
                     /gene="mnmG"
                     /locus_tag="VYO11_001499"
     CDS             9234..11147
                     /gene="mnmG"
                     /locus_tag="VYO11_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HEV1596047.1"
                     /translation="MTYHFTEEYDIIVIGAGHAGVEASLAASRMGCKVLLATINIEML
                     AFMPCNPSIGGSAKGIVVREVDALGGEMAKTIDKTYIQMKMLNTGKGPAVRALRAQAD
                     KELYSKEMRKTVENQENLTLRQTMIDEILVEDGKVVGVRTATHQEYAAKAVIVTTGTA
                     LRGEIIIGDLKYSSGPNHSLASINLADNLKELGLEIGRFKTGTPPRVKASSINYDVTE
                     IQPGDEVPNHFSYTSRDEDYVKDQVPCWLTYTNGTSHEIIQNNLHRAPMFTGVVKGVG
                     PRYCPSIEDKIVRFADKERHQLFLEPEGRNTEEVYVQGLSTSLPEDVQRDLVHSIKGL
                     ENAEMMRTGYAIEYDMVLPHQLRATLETKKISGLFTAGQTNGTSGYEEAAGQGIIAGI
                     NAALKIQGKPELILKRSDGYIGVMIDDLVTKGTIEPYRLLTSRAEYRLILRHDNADMR
                     LTEMGREIGLVDDERWARFEIKKNQFDNEMKRLDSIKLKPVKETNAKVEEMGFKPLTD
                     AVTAKEFLRRPEVSYQDVVAFIGPAAEDLDDKIIELIETEIKYEGYISKAMDQVAKMK
                     RMEEKRIPANIDWDDIDSIATEARQKFKLINPETIGQASRISGVNPADISILMVYLEG
                     KNRSISKTLQKSK"
     gene            complement(11354..11446)
                     /locus_tag="VYO11_001500"
                     /pseudo
     CDS             complement(11354..11446)
                     /locus_tag="VYO11_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(11500..13179)
                     /locus_tag="VYO11_001501"
     CDS             complement(11500..13179)
                     /locus_tag="VYO11_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HEV1596048.1"
                     /translation="MAYTLKPEEVGVFAIGGLGEIGKNTYGIEYQGEIIIVDAGIKFP
                     EDDLLGIDYVIPDYSYIVDNIDRVKAVLITHGHEDHIGGIPFLLKQANVPIYAGPLAL
                     ALIRGKLEEHGLLRNAKLYEINHNTELTFKNLKATFFRTTHSIPEPLGIVIHTPQGKI
                     VCTGDFKFDFTPVGEPADLHRMAALGEEGVLCLLSDSTNAEVPTFTNSEKVVGQSIMK
                     IIQGIEGRIIFASFASNIFRLQQATEAAVKTGRKIAVFGRSMEKAIVNGIDLGYIKAP
                     KGTFIEPNEIKDYPAGEVLILCTGSQGEPMAALSRIANGTHRQVQLQPGDTVIFSSSP
                     IPGNTTSVNKLINIISEAGVEVIHGKVNNIHTSGHGGQQEQKLMLCLIKPKYFMPVHG
                     EYRMQKVHAGLAVDTGVEKDNIFIMSNGDVLALTADSARIAGHFNAQDIYVDGNRIGE
                     IGAAVLKDRRDLSEDGVVLAVATVDFKSQMILSGPDILSRGFVYMRESGDLIRQSQRI
                     LFNAIRIALKNKDASVQSVNGAIVNAIRPFLYENTEREPIIIPMILTPDEE"
     gene            complement(13181..13414)
                     /locus_tag="VYO11_001502"
     CDS             complement(13181..13414)
                     /locus_tag="VYO11_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HEV1596049.1"
                     /translation="MIYKVFYQETKERSPRRETTRALYLDIDASSELEGRITARQLVE
                     ENRPEYNIEYIELLSDKLLDYEKETGAFEITEF"
     gene            13796..14017
                     /locus_tag="VYO11_001503"
     CDS             13796..14017
                     /locus_tag="VYO11_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000184674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1596050.1"
                     /translation="MTNQVLEENYLCDSLLAFSPPRDLCRLVCILLWIKCLDALLMLG
                     FFVWGCRDSRFTTRKFHPIYQDEVVFAFF"
     gene            complement(14230..14382)
                     /gene="cibB"
                     /locus_tag="VYO11_001504"
     CDS             complement(14230..14382)
                     /gene="cibB"
                     /locus_tag="VYO11_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000977347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibB"
                     /protein_id="HEV1596051.1"
                     /translation="MMKDLNNCREISNKELQEIKGGFGVGVGIALFMAGYTIGKDLRK
                     KFGKSC"
     gene            complement(14384..14569)
                     /gene="cibA"
                     /locus_tag="VYO11_001505"
     CDS             complement(14384..14569)
                     /gene="cibA"
                     /locus_tag="VYO11_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000180803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibA"
                     /protein_id="HEV1596052.1"
                     /translation="MTNFDILDNQFLSLSENELSDIDGGLAPLVIFGVAVSWKAIAGG
                     TALIGSGLAAGYFLGGD"
     gene            14747..15430
                     /gene="tsaB"
                     /locus_tag="VYO11_001506"
     CDS             14747..15430
                     /gene="tsaB"
                     /locus_tag="VYO11_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000865689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HEV1596053.1"
                     /translation="MKVLAFDTSSKALSLAILEDKQVLAETTINIKKNHSITLMPAID
                     FLMASLDWTPKDLDRIVVAEGPGSYTGLRIAVATAKTLAHTLNIELVGMSSLLVLVPY
                     QQEGLFVSLMDARRNNVYVGFYENAKPVMPEAHLPFERVIELIKGASQVTFVGEVGPF
                     VEQIQEYLPRTNFKETLPNAANLALWAWDKEADSLHDFVPNYLKRVEAEENWLKNHTE
                     SGESYIKRL"
     gene            15427..15864
                     /gene="rimI"
                     /locus_tag="VYO11_001507"
     CDS             15427..15864
                     /gene="rimI"
                     /locus_tag="VYO11_001507"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HEV1596054.1"
                     /translation="MIEIKRIQKHSDLAQAIYAVMIAVYPVSPWTLEQIQADLSQDQT
                     WYALAYDGAEVIGFLAVQENLFEAEVLQIAVKGAYQGQGIASALFAQLPTDKEIFLEV
                     RQSNQRAQAFYKKEKMAVIAERKAYYHDPVEDAIIMKREIDEG"
     gene            15854..16864
                     /gene="tsaD"
                     /locus_tag="VYO11_001508"
     CDS             15854..16864
                     /gene="tsaD"
                     /locus_tag="VYO11_001508"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HEV1596055.1"
                     /translation="MKDRYILAFETSCDETSVAVLKNDDELLSNVIASQIESHKRFGG
                     VVPEVASRHHVEVITACIEEALAEAGITEEDVTAVAVTYGPGLVGALLVGLSAAKAFA
                     WAHGLPLIPVNHMAGHLMAAQSVEPLEFPLLALLVSGGHTELVYVSEAGDYKIVGETR
                     DDAVGEAYDKVGRVMGLTYPAGREIDELAHQGQDIYDFPRAMIKEDNLEFSFSGLKSA
                     FINLYHNAEQKGESLSTEDLCASFQAAVMDILMAKTKKALEKYPVKTLVVAGGVAANK
                     GLRERLAAEITDVKVIIPPLRLCGDNAGMIAYASVSEWNKENFAGWDLNAKPSLAFDT
                     ME"
     gene            complement(16904..18210)
                     /locus_tag="VYO11_001509"
                     /pseudo
     CDS             complement(16904..18210)
                     /locus_tag="VYO11_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011680908.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(18486..18837)
                     /locus_tag="VYO11_001510"
                     /pseudo
     CDS             complement(18486..18837)
                     /locus_tag="VYO11_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(18944..19236)
                     /locus_tag="VYO11_001511"
                     /pseudo
     CDS             complement(18944..19236)
                     /locus_tag="VYO11_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            19479..>19775
                     /locus_tag="VYO11_001512"
     CDS             19479..>19775
                     /locus_tag="VYO11_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 1 protein"
                     /protein_id="HEV1596056.1"
                     /translation="MQYSCGKININIPDGYGDIKDIVFSAHIIVRYNNGHCGGIDPHI
                     IGLCKKQIRRMSLYPILIIVSRDSKVIDDYKNLDIAYVDCTQCSNNFETALHVKN"
BASE COUNT         5968 a         3536 c         4407 g         5864 t
ORIGIN      
        1 ttagtctagc tatagtcttt ccatggggct ggtcgatata atgtaaggga gcttgagttg
       61 ttagtggagg ataaaatgtt aagagtaata gtagttattc aatctttagt aataatactg
      121 cttgctgttg ctttattatt atctcggaaa aactttgatt cgttaaatgt tgttcttata
      181 atgatgatcg tatcacaatt gttgttatta gtatatttga taaaatcagg gaatcagtga
      241 ttagctgtta tttgaattaa gtaaactgtt aagcttcaag cagtaactgg ttttaaatat
      301 ttaaaataag ataaaggaag gaagtctaat ttaggtaact aaacaaagcc tgcgatcact
      361 tgttaggaaa ccatcctaac catgcttaat aaaaaggaga aaacaaatgg aacttgtatt
      421 accaaataat tatgttgtga ttgatgaaga agagatgatg taccttgatg ggggtggtgt
      481 tggttgtaac tggtggaata gtagaggtag ttttgcaaca gttctggatg taggtttggc
      541 catctatagt ggtggtgcaa caatttattc tgcttatgcg ataaaaaaag ctatctcagc
      601 taatagaggg gctattacga gaacattacg tagtttaata attaaacatg taggtagtgc
      661 agctggccat ttagtcaata ctgcactaaa cgttgcacta actgttactg gattttcact
      721 aggtggagca atcgcatatg gggctgattg ggctgacggt agcttagatg gttatatttt
      781 tgcttaaaat gaaacatttt tttgcaggaa ttggtgaaat aaactttgta agttatttat
      841 tgtatatatg tgtaggaata gccccttttt ttcacgtata tataataggt tctgaaatga
      901 attttgtgaa aatagtgtta tctattttgg gaattatatt tgtttgtatt ttaactattg
      961 ctcgaattta taggactttt ttctataaag aatagtttgg acttgaaatg tatttaaaaa
     1021 caagaggttg gtagattatc agcctctttc ttgtcgttga aaaagtgaga tatattgact
     1081 tttgaaaaaa atgtcataat tgagttggga taaacgtaaa agtcatactt tctcgttaaa
     1141 tcgttcggcg attctatgaa aaggtcgagg agctccctcg accttttttt ataatttctt
     1201 tggttaataa tgggtctcta cttctttttt gagatgagac agcatagaag tttcctcggt
     1261 cagctccaga agggagaacc ctttttggat aagtttagaa tcgtctgtac aaatcccaat
     1321 gcggacatag cagatagcca gcctatcgta gcttttctta ttcttggcgt cctctagtaa
     1381 agtgtagcag atttgcttac acatgttttt atcttgattg tatagataga gtgtggaaag
     1441 gttgagcagg attgctattc gcaagtcata taaatgttga tagtttttat agacttctaa
     1501 gcgttgcaag atttttccag tgatgagatg gaggtattca atgggaaaac tgaaaagaat
     1561 ggtattgagg atttttagat cactctcata ccatgtatct tgtttttcaa tttttctcca
     1621 aagttttttg acaacctgtt ctgcgtgatc tgatagttcc cctgccccgt gttgacggat
     1681 ataaatgaca acttcaagca tatctctgat ttcttctata gggagatcgt ggtgggtctt
     1741 gaggtagtct tggcattttt gaaataaatt gacaagatcg ctggtcccga taatggaacg
     1801 catattgaga taggtttgca taatctctgt gcgttgactt ggttgataaa gttgacagat
     1861 atattcaaac tcttcaaaac tcatattgat ttgacggaga agaaattcca tattttcata
     1921 ttttggggtt gtcttgccac tttcgatttt tgataagctg gttcttgaga gaacaccccc
     1981 acagacctct tcttgggtca gcccctttga ctcacgtatt tctttataga cctttccgaa
     2041 atcataacgc atgattttct cctttctgtg aaaaaagtta acaaataata aaatcttgtt
     2101 aaaaatattg tatcatagca atgtaaaaag taaaaaagaa agtcgaaata aatttgtgaa
     2161 aaaagttaac gtaattttaa aatgagctta ataagaggta tgatgtaggt agaaaataaa
     2221 gataggagaa aaagtatgaa taaaaaaata ttttgtattc tagtatgtat gatatcattg
     2281 attagtctgg ccataatctt tccatggggc tggtcgatat aatgtaaggg agcttgagtt
     2341 gttaaaggag gcttagtcct tggacaaaaa tctgctgtac tacaatgctt ggaaagatat
     2401 caagaacaaa gaatgatacg attgaaacta aactgattca agaactactg ggcagtgatt
     2461 gaggtttggg tgacatcaaa gaaaagttag attaattcta aagaattgag tatttctatg
     2521 ttaaaaaaat atccttgtac gattcaacat gatcagtcag attgtgctgc ggcagttgtt
     2581 tcaacagttc ttttatctta caaaaaggaa ctatcaatca tgaagattcg ggaaattatt
     2641 ggtacagaca tgtatggaac gactgtcagt ggtattgttt caggtctgaa taagttgaat
     2701 tttacagtaa aagctgttcg agtagcactg gaagatttga ctccaaaatt aacatttcct
     2761 gcgattcttc aagttaagaa tgatttaggt caaaatcatt ttgtggtatt acatagtata
     2821 aaggagaaaa taaagggaac tcgtattacc aaataattat gttgctcttg agcaagagga
     2881 gatgatgtat cttgatgggg ggggttattt aagcaagagt gcttgtcaag gaatttgcgc
     2941 agctttagct atgagtccag gaacttttat agcattgact ggagctgcag ttttaacaaa
     3001 aaaactaata aactatatta aggttggagg ccttggaggt tggcttattg gtgcagcagc
     3061 aggtgtattg gctcttatct ttttgataaa aatttgtgta gatactacga taaaattttt
     3121 attcatcaga ttatttgaca caagtacttt aatgaagagg agaatatttt ttcttttcgc
     3181 attggatgtt atagcttact tatttttagg atatctttta gtgattcaaa aagcaggcta
     3241 tttgttttcg gttttacttc ttttttctaa tttttcagtt ccatttatca aagcaaagga
     3301 atacgaatta tttaaaaata gcaagtaata gaaacatagg ttaaatctta gaacggctta
     3361 aaatcagata tgataaaggg aaatagtctt atctaggtaa ctaagtgcta caaacacagt
     3421 cgaggatcac ttgttaggat tacattttaa tcatgcttaa taagaatgga gaattcctat
     3481 gggaattgta ttactctgaa gtttcgaata ccttagttct cgtgattttg agctgttcta
     3541 gctttagaat ccttcagaat gtaaaatttt aagcagtcaa agacttagaa tagcctggaa
     3601 acatttattt tatagcaatt ctaggcttag aattgctcat atatatgtat ttgagctgct
     3661 cgatagttag gacagctcta ttctgagaaa tctgagctat caatgcttca gaatagtatt
     3721 tcgcaaatgg tttttattga agaggtgatt gttttatgat agtctaaaat aaaactgatt
     3781 taatggagta aatggagaat cgttacatga aacatttttt tgcaggaatt ggtgagataa
     3841 aacttgttgg ctacttattg tatatatgtg taggactagc ccctcttttt catatatata
     3901 tgtcataggt tcggaactga gttttgtgaa aatagtgtta tctattttgg gagttgtatt
     3961 tgtaagtatg ttaactattg ctcgaattta tcggactttt ctataaagaa tagtttggac
     4021 ttgaactgta tctaaaaaca gaggttggtc gattatcagc ctctttcttg tcgttgaaaa
     4081 gagtgagata tattgacttt tgaaaaaaag atgtcataat tgagttggga taaacctaaa
     4141 agtaatatag tagattgaat ctggaatagt ccgttatgac tgttaaaata tttctagaaa
     4201 ttaatttgac tttcctaatc gatttgttca catcttgttt caatctacta tactttttcg
     4261 ttaaaccgtt cggcaattca tggtgacatg gacacatagt agtaagcaca ctatgtggct
     4321 tggcagagct aaaaactgtt cccttgcgat aagcctaata agcacaacat agggagttag
     4381 agaagccgac tctaatcaac cactttgggc agtagtgaga actgccccgt gctttttatt
     4441 ttgagaaaat atggagtttg tcgttgaaat tacttgattg tattttggat tatcaagaaa
     4501 gattcaatgg aaaaacatgt caagtatcga cgaattataa gtatttagag attttcaaag
     4561 tgaatttttg cttgactgat ttacatcatt tatttggctt acacaaaatc acacgagatt
     4621 atgctagtca aacaaaacct gctattcaag ctggtgtttt tattttagaa gattttagaa
     4681 atatcctatt gtacaatgat gtaatcgaaa ggatatcttt atatgagttt ataggtgaca
     4741 ttttctattt taaaataaca agttgttgca tcgtagctaa ggatttatct aaaagtacta
     4801 tgaaattgga cgtcatattt tttgaggata aaaataaaag atccgcagtt ttaggtttac
     4861 gaagagacaa aagcggagta tttaaaccag ttactctaca ttttacaagc gctaagaaat
     4921 atgctaaagt tcgtaaaaca gatgtgaaag aaatgaaatg gctataaaga ttgtccgcag
     4981 gcttaagctt gcgttttttg ttgtttaacg aaattaaaaa acaagctctc tcatcggaaa
     5041 tgtttttata ggaatgaagg aagatgatgc tatgtttaaa aagagaatcg aaaagggcaa
     5101 aagtagtgtc tttatctttt tggagtagaa gcttatgata tagaaatttg taataaaaat
     5161 gtaatataaa acatttgaca aatatttacg gggggagtat acttaatata agtatagtct
     5221 aaaaatgact atcagaaaag aggtaaattt agatgaataa gaaaaaaatg attttaacaa
     5281 gtctagccag cgtcgctatc ttaggggctg gttttgttac gtctcagcct actgttgtaa
     5341 gagcagaaga agctcccgta gctagtcagt ctaaagctga gaaagactat gatgcagcag
     5401 tgaaaaaata taaagctgct gaggaagact taaaaaaagc agaagctgct cagaggaaat
     5461 atgacgagga tcagaagaaa actgaggaga aagcgaaaga aacagaagaa gcttctaaaa
     5521 gacaacaagc tgcaaatctg aaatatcaac taaagttgcg tgaatatctt aaatatatac
     5581 aagaaaaaaa taaggaaaaa atagctaaag ctgagaaaga aatgaacgaa gctaagcaag
     5641 aggaagacaa agaaaaggca aaccttaata aagttctcgc aaaagtaatt cctagcgata
     5701 gagaattaga aaaaactaga caagaagcag aaaaggctaa aaaaaatata ccagaactta
     5761 agaaaaaagt agaagaagcc aaacaaaaag tggatgcagc caaacaaaaa gtggatgcag
     5821 aacatgctaa agaagttgct cctcaagcta aaatcgctga attggaaaat caagttcata
     5881 ggctagaaca agatctcaaa gatattaatg agtctgactc agaagattat gttaaagaag
     5941 gtctccgtgc tcctcttcaa tctgaattgg ataccaaaaa agctaaacta ttgaaacttg
     6001 aagagttgag tggtaagatt gaagagttag acgctgaaat tgcagaactt gaagttcaac
     6061 ttaaagatgc tgaaggaaac aataatgtag aagcctactt taaagaaggt ttagagaaaa
     6121 ctactgctga gaaaaaagct gaattagaaa aagctgaagc tgaccttaag aaagcagttg
     6181 atgagccaga aactccagct ccggctccag ccccagctcc agctccagaa gccccagctc
     6241 cagctccagc tccggctcct aaaccagctc cagctcctaa accagctcca gctcctaaac
     6301 cagctccagc tcctaaacca gctccagctc ctaaaccaga aaagccagca gaaaaaccag
     6361 ctccagctcc taaaccagaa actccaaaaa caggctggaa acaagaaaat ggtatgtggt
     6421 acttctacaa tacggatggt tcaatggcaa caggctggct acaaaataat ggctcatggt
     6481 actacctcaa cgctaatggt gctatggcaa caggttgggc taaagtcaac ggcttatggt
     6541 attacctcaa cagcaatggc gctatggcga caggatggct ccaatacaat gattcatggt
     6601 actacctcaa tactaatggt gctatggcga caggttggct agaatacaat ggttcatggt
     6661 actacctcaa tactaatggt gctatggcga caggttggct agaatacaat ggttcatggt
     6721 actacctcaa cgctaatggt gctatggcga caggttggct agaatacaat ggctcatggt
     6781 actacctcaa cgctaatggt gatatggcta caggatgggc taaagtcaac ggttcatggt
     6841 actacctaaa cgctaacggt gctatggcta caggatgggc taaagtcaac ggttcatggt
     6901 actacctaaa cgctaacggt tcaatggcaa caggttgggt gaaagatgga gatacctggt
     6961 actatcttga agcatcaggt gctatgaaag caagccaatg gttcaaagta tcagataaat
     7021 ggtactatgt caatggctta ggtgcccttg cagtcaacac aactgtagat ggctataaag
     7081 tcaatgccaa tggtgaatgg gtttaagccg attaaattaa atcatgttaa gaacatttga
     7141 cattttaatt ttgaaacaaa gataaggttc gattgaatag atttatgttc gtattcttta
     7201 ggtacctatc ttatgatttc aggaaatgtc attaaaaaaa cgactccttt tctctaactt
     7261 gaaaaataga ttagagaaaa tgggttgttt tatttattat agttacttga atgaagataa
     7321 gaagaaggta tactcacgtc attcacataa tctgtatgtt gactataagt tttaaaaaac
     7381 aatttttaag ctcttccttg tcttctctaa ccaagcgtgt tataatgaat actgctcaag
     7441 cgaccttcaa tcgtgaagca cacacgacct tcaatcgtga ataaacgaat agatgggaga
     7501 cttaccatga gtgataactc taaaacacgt gttgtcgtgg ggatgagtgg tggtgttgat
     7561 tcgtcggtga cggctctttt gctcaaggag cagggctacg atgtgatcgg tatcttcatg
     7621 aagaactggg atgacacaga tgaaaacggc gtttgtacgg cgaccgaaga ttacaaggat
     7681 gtggttgcgg tggcagacca gattggcatt ccctactact ctgtcaattt tgaaaaagag
     7741 tactgggacc gcgtttttga gtatttccta gcggaatacc gtgcagggcg cacgccaaat
     7801 ccggacgtta tgtgcaataa ggaaatcaag ttcaaggcct ttttggacta tgccatgacc
     7861 ttgggggcag actatgtagc gactgggcac tatgctcgag tggcgcgtga tgaggatggc
     7921 actgttcaca tgcttcgtgg cgtggacaat ggcaaggatc agacttattt cctcagccaa
     7981 ctttcgcaag aacaacttca aaaaaccatg ttccctctgg gacatttgga aaagcctgaa
     8041 gtacgcagac tagcagaaga agcaggtctt tcgactgcta agaagaaaga ctcgacaggg
     8101 atttgcttta tcggagaaaa gaactttaaa aactttctca gcaactacct gccagctcag
     8161 cctggtcgta tgatgactgt ggatggtcgc gatatgggcg agcatgctgg tctgatgtac
     8221 tatacgattg gtcagcgtgg cgggcttggt atcggtgggc aacacggcgg tgacaatgcc
     8281 ccttggttcg ttgtcggaaa agatctaagc aagaatattc tctatgtagg ccaaggtttc
     8341 taccatgatt cgctcatgtc aaccagccta gaggctagcc aagtccactt tacttgtgat
     8401 atgcccgagg agtttacgct agaatgtacg gctaaattcc gttaccgtca gcctgactct
     8461 aaggtgaccg tccatgtcaa aggagacaag gcagaggtca tctttgcgga accacaacgc
     8521 gccattacac caggacaggc agttgtcttt tacgatggcg aagagtgtct aggtggcggt
     8581 ttgattgaca atgcttaccg cgatggacaa gtttgtcagt acatttagat tgacaaattt
     8641 tctcaatttg ctacaataat aacagcaata gaaatgatgg tcaaagctca tggatgttgc
     8701 aggctttttt gtcctgcact tctttgtagt tttgactgtt tttgtgtcgt ttaagggaaa
     8761 ggacaagaat gactcaacaa gactttcgga caaaagtaga caatacggtt tttggtgttc
     8821 gggcgacagc cttgattgtc caaaatcaca agcttctagt taccaaagac aagggcaagt
     8881 attacactat tggaggtgcg attcaagtta acgaaaaaac ggaagacgcg gtagtccgtg
     8941 aagtgaagga agaactgggt gtcaaagctc aagctgggca gctagctttt gtggttgaaa
     9001 atcgttttga acaggacggt gtttcctatc acaatatcga atttcattat ctggtggact
     9061 tgctggagga tgccccattg accatgcagg aagatgagaa aaggcagccc tgtgagtgga
     9121 ttgacttgga taagtttgag gatatccagc tagttccagc ctttttaaaa acggccctac
     9181 cagattggga aggccaacta agacacattc atcgtgagga ataggagaga aacatgactt
     9241 atcattttac tgaagaatac gatattattg taattggtgc gggacacgct ggggttgagg
     9301 cttccttggc cgctagccgt atgggctgta aggttctact tgcgaccatc aatattgaaa
     9361 tgctggcttt catgccttgt aatccctcta tcggtggttc tgctaagggg attgtcgtac
     9421 gtgaagtcga tgccctcggt ggcgagatgg ccaagactat tgacaagact tacatccaga
     9481 tgaagatgct caacacagga aagggtcctg ccgttcgtgc ccttcgtgcg caggctgaca
     9541 aggaacttta ctctaaggaa atgcgcaaga cagttgaaaa tcaagaaaat ctgacccttc
     9601 gtcagaccat gattgatgag attttggtgg aagatggcaa ggttgtcggt gtgcgtacag
     9661 ccacccatca agaatatgct gctaaggctg ttattgtgac gacagggact gctctccgtg
     9721 gggaaattat catcggagac ctcaagtact catcaggtcc taaccacagc ttggcttcta
     9781 ttaacctagc tgacaatctc aaggaactgg gtctcgaaat cggtcgtttc aagacaggaa
     9841 cccctccacg tgtcaaggct tcttctatca attacgatgt gacggaaatt cagccaggag
     9901 acgaagtgcc taatcatttc tcatacactt cacgtgatga ggattatgtc aaagatcaag
     9961 tgccatgctg gttgacctat accaatggta ccagtcatga gattattcaa aacaacctcc
    10021 accgtgcgcc tatgtttaca ggtgtggtca agggagtggg gcctcgttac tgtccgtcga
    10081 ttgaagacaa gattgtgcgc tttgcggaca aggaacgtca ccaactcttc cttgagccag
    10141 aagggcgcaa tactgaggaa gtctatgttc aaggactttc aaccagtcta cctgaggatg
    10201 tccagcgtga cttggttcat tccatcaaag gtttggaaaa tgcagagatg atgcgaacag
    10261 gttatgccat tgagtacgac atggtcttgc ctcatcagtt gcgtgcgact ttggaaacca
    10321 agaaaatctc aggtctcttc actgctggtc agacaaatgg aacatcaggt tatgaagaag
    10381 ctgctggcca agggattatc gcgggtatca atgcggctct aaaaatccaa ggcaagcctg
    10441 agttgatttt gaagcgcagt gacggttata tcggggtgat gatcgacgac ttggtgacca
    10501 agggaaccat tgaaccttac cgtctcttga ccagtcgtgc tgaataccgt cttattcttc
    10561 gccatgacaa tgctgatatg cgcttgactg agatgggacg cgagattggc cttgtggacg
    10621 atgaacgctg ggctcgtttt gaaatcaaga aaaatcaatt tgataatgag atgaaacgcc
    10681 tagacagtat caaactcaag ccagtcaagg aaaccaatgc caaggttgag gagatgggct
    10741 tcaagccgtt gacagatgcg gtgacggcca aggaattcct tcgccgtcca gaagtttctt
    10801 accaagatgt ggtggccttc atcggaccag ctgcagaaga cttggatgac aagattatcg
    10861 aattgattga aacagaaatc aagtacgaag gctatatttc caaagccatg gatcaggttg
    10921 ccaagatgaa acgtatggaa gaaaaacgca ttccagccaa tatcgactgg gatgacatcg
    10981 attctattgc gacggaagct cgtcagaagt tcaaactcat caatccagaa accatcggcc
    11041 aagccagccg tatttcggga gtaaacccag cagatatttc tattttgatg gtgtatctgg
    11101 aaggtaaaaa tcgtagtatt tctaaaactc ttcaaaaatc aaaatgatac gtcgtcggct
    11161 tcttacgaat gagttcaaag cttggctttg attcatctcc agcctcccat agtttcctga
    11221 actatgggag ctaactcaag ttatgctttc gcttagcctt ctagtctgat ttcgattttt
    11281 attgatactc ttcgaaaatc tcttcaaacc gcgtcaacgt cgccttgccg taggtatggc
    11341 tactgacttc gtcagttcta tctacaacct caaagcagtg ctttgagcaa cctacggcta
    11401 gcttcctagt ttgctctttg attttcattg agtatgagtt ttaatctcaa aagaaagcat
    11461 agagaaaaac agctccgagg acggggctgt tttcttgctt tattcttcat ctggtgtgag
    11521 gatcatcggg atgatgatcg gttcacgttc ggtattttca tagaggaagg ggcgaatagc
    11581 gttgacaatg gcaccattga cagattgcac gctagcatcc ttatttttca gtgcgatacg
    11641 aatggcattg aagaggatac gctggctttg gcgaatcaag tcgccagact ctctcatgta
    11701 gacaaagcct cggctgagga tgtctggacc agatagaatc atctgcgatt tgaagtcaac
    11761 agttgcgact gctagaacga caccgtcttc agatagatcg cgacgatctt tgaggacagc
    11821 tgcgccaatt tcaccgatac gatttccatc gacatagata tcttgggcgt tgaaatgacc
    11881 tgcgatacga gctgagtcag cagtaagggc aagcacatcg ccattgctca tgataaagat
    11941 attgtccttc tcaacaccag tatccactgc tagtccagcg tggacttttt gcatgcggta
    12001 ttcaccgtgg acaggcatga agtattttgg cttaatcaag cagagcatga gtttttgctc
    12061 ttgctgacca ccgtgtccag atgtatggat attgttcact ttaccgtgga taacttcgac
    12121 accagcttca gaaatgatgt taatcagctt gttgacgcta gtagtgtttc cagggatggg
    12181 actagaagag aagataacgg tatcacctgg ttgtaattgt acttgacggt gggttccgtt
    12241 ggcgatacga gagagggctg ccataggctc accctgacta cctgtacaga ggataagaac
    12301 ttctcctgca ggataatctt tgatttcatt tggctcgata aaggttccct taggagcttt
    12361 gatgtagcca agatcgattc cgttgacaat ggccttttcc atagaacgac caaagaccgc
    12421 aatcttgcgt ccagtcttaa cagcagcttc tgttgcctgc tggagacgga agatatttga
    12481 ggcaaaggat gcaaagatga tacgtccttc aataccttgg ataatcttca taatggactg
    12541 accaacgact ttttcagagt tggtaaaggt tggtacttcc gcatttgtcg agtcagacag
    12601 gagacagagt acgccttctt caccaagcgc agccatacga tgcaagtccg caggttctcc
    12661 aactggagta aagtcgaact taaagtcacc cgtacagacg attttccctt gaggagtatg
    12721 aatgacaatc cccaaaggct ctggaataga gtgagtcgtt ctaaagaaag ttgccttgag
    12781 atttttaaag gtcaactcgg tgttgtggtt gatttcgtaa agtttggcgt tgcgcaagag
    12841 gccgtgttct tcgagtttcc cacggatcaa agccaaggca agcggtccag cataaatagg
    12901 gacatttgct tgcttgagta ggaacggaat cccaccaatg tggtcctcgt gtccgtgtgt
    12961 gattaaaaca gccttgacgc ggtcgatatt gtctacgatg taagagtagt caggaatgac
    13021 atagtcgata ccaagcaagt catcttctgg gaatttaatc ccagcatcga cgatgataat
    13081 ctcgccttgg tattcaattc cgtaagtgtt tttcccgatt tctcctagac caccgatggc
    13141 aaaaacgccg acttcttcag gtttaagagt gtaggccata ttagaactcc gtaatttcga
    13201 aggcgccagt ttctttttcg taatcgagca atttgtcaga caagagttcg atatattcga
    13261 tattgtactc tgggcgattt tcttcgacaa gttggcgagc agtgatacgg ccctcaagtt
    13321 ctgagctggc atcgatgtct aggtaaagcg cgcgtgttgt ttcacggcgt gggctacgtt
    13381 cttttgtttc ttgataaaaa actttgtaaa tcatatagtt cctttctatt tacaggtcag
    13441 cttattccaa acttttagca gatatttgct tgatttcatt ccattttgtg tctagattga
    13501 ccttgattcg ttacaattat ttcaattata ccacaaaatg aaaaattagt aaaagacgga
    13561 aacgagaaag ttaggggacg atttcttcgg taagcgtttg cgaaaataaa gaaaatgtat
    13621 tatgttgata acggaagtga aatttattgc ttgtcataat tccatataga ttttaagtca
    13681 aggaggttgc cctatgtata acttatttgc ttttgctatc ggagttcgtt tgctagcttt
    13741 tatcgttttt gttttgcgtt tatggaggaa atcttctatt tgccaaactg gaacgatgac
    13801 aaaccaagtt cttgaggaaa attacctttg tgactctcta ctcgcttttt ctcctcctcg
    13861 tgacctatgt cgtttggttt gtattttact ttggattaaa tgcttagatg ccctgcttat
    13921 gctggggttt tttgtttggg gatgtagaga tagtagattt acgacacgaa aattccaccc
    13981 catctatcaa gatgaggtgg tctttgcatt tttctaaaat gacatgacaa tggaattttc
    14041 aaagcttatt atttttatgg gagtcattgt tctgctcaaa aatagagttg aagcataaaa
    14101 ataaaacaat acaaacagat aaatcgaatg gtaaagggat agtagtaatg ttcaaatcat
    14161 tgagaatgct gagcaaactg taagagatga agacaataaa atttatcctt ctaaaaatgt
    14221 gtttcttatc tagcatgact taccaaactt tttacgaagg tcttttccaa tggtataacc
    14281 tgccataaat aaagcgatac caacacctac accaaagcca cccttgattt cttgcaattc
    14341 cttattagaa atttcacgac agttgttcaa atctttcatc atattaatct cctcctaaaa
    14401 aataaccagc tgccaaacca gaacctataa gtgctgttcc acctgcaata gctttccaag
    14461 atactgctac tccaaagata accaagggag cgagaccgcc atcaatatct gataattcat
    14521 tttcagataa ggataaaaat tgattgtcaa gaatgtcaaa atttgtcatt gaactttcct
    14581 ccttttttct tgttcacttt tatattcgga aaagaaaagg aaaagtgagc atttttttaa
    14641 attattttta gttaagtgag ggcactcttg tctgggggca aagaaaattc ccatgtgcca
    14701 gcttttgtag tataatagta agcagacaaa aagataggaa tgtgttatga aagtattagc
    14761 ttttgatacg tccagcaagg ctctttctct cgctatttta gaggacaagc aggttcttgc
    14821 cgagacgacg attaatatta agaaaaatca cagtattact cttatgcctg ccatagattt
    14881 tttgatggca agtttggatt ggacacccaa ggatttggac cgaatcgtgg tagctgaagg
    14941 gccgggtagc tacacaggct tgcgaattgc ggtagccact gccaagactt tggctcatac
    15001 tctgaacatc gagttagttg gtatgtctag cctcttggtt ctggtaccct accaacaaga
    15061 aggcttgttc gtctctttga tggatgcgcg tcgcaacaat gtttatgtag gattttatga
    15121 aaatgctaaa cccgtcatgc cagaagctca cttacccttt gagcgagtga ttgagttaat
    15181 caagggtgct agtcaggtta cctttgtcgg agaagttggc ccctttgttg agcagattca
    15241 agaatacttg ccaaggacta atttcaaaga aaccttgcca aatgcagcta atctagctct
    15301 atgggcctgg gacaaggaag cagactcctt gcatgatttt gtgccgaact acctcaagcg
    15361 tgtcgaagct gaggaaaact ggctcaagaa tcacaccgag tctggcgagt cttacattaa
    15421 acgcttatga tagaaatcaa acgaatccaa aaacattctg acttggctca agccatctac
    15481 gctgttatga tagctgttta cccagtcagt ccttggacgc tggaacaaat ccaagcagac
    15541 ctgtcccaag accaaacttg gtatgctttg gcttatgatg gggcagaagt gattggattt
    15601 ctagctgtgc aggagaatct ttttgaagca gaagtcctgc aaatcgctgt caaaggagct
    15661 tatcagggtc agggaattgc gtcagccttg tttgctcaat tgccgacaga caaggaaatt
    15721 ttcctcgaag tcagacagtc aaatcaacga gcgcaagcat tttacaagaa agaaaagatg
    15781 gcagttatcg ctgagcgaaa ggcctactac catgacccag tcgaggacgc cattatcatg
    15841 aagagagaaa tagatgaagg atagatatat tttagcattt gagacatcct gtgatgagac
    15901 cagtgtcgcc gtcttgaaaa acgacgatga gctcttgtcc aatgtcattg ctagtcaaat
    15961 tgagagtcac aaacgttttg gtggcgtagt gcccgaagta gccagtcgtc accatgtcga
    16021 ggtcattaca gcctgtatcg aggaggcatt ggcagaagca gggattaccg aagaggacgt
    16081 gacagctgtt gcggttacct acggaccagg cttggtcgga gccttgctag ttggtttgtc
    16141 agctgccaag gcctttgctt gggctcacgg acttccactg attcctgtta atcacatggc
    16201 tgggcacctc atggcagctc agagtgtgga gcctttggag tttcccttgc tagccctctt
    16261 ggtcagcggc ggacacacag agttggttta tgtttcggag gctggcgatt acaagattgt
    16321 tggggaaacc cgtgatgatg cggttggtga ggcttatgat aaggtcggtc gtgtcatggg
    16381 cttgacctat cctgcaggtc gtgagattga cgagctggct catcaggggc aggatattta
    16441 tgatttcccc cgtgccatga ttaaggaaga taatctggag ttctccttct caggtttgaa
    16501 atctgccttt atcaatcttt atcacaatgc cgagcaaaag ggagaaagcc tgtctacaga
    16561 agatttgtgt gcttccttcc aagcagcagt tatggacatt ctcatggcaa aaaccaagaa
    16621 ggctttggag aaatatcctg ttaaaaccct ggttgtggca ggtggtgtgg cagccaataa
    16681 aggtctcaga gaacgcctag cagccgaaat cacagatgtc aaggttatca tcccccctct
    16741 gcgactctgc ggagacaatg caggtatgat tgcctatgcc agcgtcagcg agtggaacaa
    16801 agaaaacttc gcaggctggg acctcaatgc caaaccaagt cttgcctttg ataccatgga
    16861 ataaagagtg gctctttgtc aagtgtagtg ggtaggcgaa aagctacaat ctggagagta
    16921 cgaaattcgt actctctttt ttgatgttca aagtcatcaa aatccgtttt ttaaaattgt
    16981 taaagttccg gaaaccaaag gctttgcgct tgataacctt aatcaaatta ttggtcgctt
    17041 caagtttagc gttggaataa ggcagcttaa gtgcgttgat aatcttatct ctatccctta
    17101 aaaaagtcca aaagaccgtt tgaaaaagcg gatgaaccgt tggcagttct tgctcaatca
    17161 atccaaagaa atggtcggca ttcttctctt gaaaatgaaa gagaaggagt tgatagagtt
    17221 cgtagtgaac ctgtaatccc tcagagtaag aaagcagctt atctcgtact tcccgatggg
    17281 ttaagtgcat tcgaaacgtg gactgataga atcgtttctg acagagcttg aagctatcct
    17341 ggtgtagtaa atcagtccag tggactgatt tagcccgagc ctagaaacga aaaagcgagg
    17401 gttccaaaag cgcttgagcg cccgatactc caaggatttt cggtcaaatt ggttcatgat
    17461 ttggattcgt actcggttca tagctcggct cagatgttgg acaatgtgga agcggtcaag
    17521 aacaatcttc gcctttggaa agagttgctt agcgagccga taataagggc tgtacatgtc
    17581 catggtgatg acctcgacca gctcccgaac ctctctctga tagcgttgga aatggtttcg
    17641 aatcaccgca tgagttcgcc cgtctaaaat tgcgaggatg gatttggact caaaatcttg
    17701 ggcaatgaag ctcattttgc tctttttgaa gctatactca tcccaactca taacttttgg
    17761 caacttggtc caatcggttt caaacttaaa ttccctcagt tttcggatga cggtggaagt
    17821 tgagaccgcc aatctgtggg caatctcagt catagactgc ttttcaagga ggagctgagc
    17881 gattttttgt ctcaccatgt tggaaatctg gcaatttttc ttgacaatgg atgtttgaga
    17941 aacgaccacc ttaaggcaat tcttgcactg aaagcggcgc tttttgagat gcagtaccgt
    18001 gggtaaaccc tgacagtcga gaagcggaat tttagaggct ttctggaagt cgtatttgat
    18061 catcttccct tgacaatgag gacaaggagg agcgggggaa tccaactttg cctgaacgac
    18121 tagatgggtt tggtatttca gaacagacaa gattttgata tttttgtctt ccaatccgag
    18181 caaatctgtg gtattcttaa gttgttccat atgaaccctt tctaatgagt tggttagacg
    18241 cttttcatta taggtcatat ggggcttttt ttctacaaga aacgacccta taattcctgg
    18301 ggtgggatta cccactacag aaattataga gccaaagcat tccaaagtct tgtctgactc
    18361 tggaatgttt tctgttcaca gttgttttgt aactgcctaa taagtaaccg cgctataacg
    18421 aggtatctac cgagattgtc aattctccag tatactgtta taaaaaacaa aactggagga
    18481 tttttttatg tccccccatc gtcccatcga ctgttccgta gctgcccaat aacggagtat
    18541 agtcggctga aacaagaata ggacaaaagt gcctcaagaa aagcatcgta atttgacaat
    18601 attattctga gatgtttttg atgtaagccc atattttctc aatgggatta tactcgggtg
    18661 aataggtagg aagtggtaac agtctatgcc ctgctcctta cacatgttca ttctgtgaaa
    18721 ccttgcattg tccataatga taagggatgg tgtatctaaa gtaggtagta agaatttttg
    18781 gaagcaagct tcgaaaaagt cactcgtcat cgtatcttta taggtcatcg gagccatagt
    18841 atattgaaac aaaaaagagc attagtactt ctataacagt atcgcaatct ctggtgtgcg
    18901 ttgtctcgat cttaattcaa ataattatat cttcttccag agagactaac tgcctgctca
    18961 aggctcgatc atattcgaga taaaaatagg tcttaacccc tgtctcataa atataaatag
    19021 gagtcaggta gcttaagtga ttcaattctt taaggaaccg atttactttt tctgggtctt
    19081 gttcgcagta ggtacgctct tttttagact atatcccata gcctttagag cgtaatgaat
    19141 agttgttgga ggacagttga attcagcagc tatttcagtc aaataagcat cgggatgagt
    19201 ttcaatatag atctttaatt tatctctatc aactttttca attaatagtg gaagttttct
    19261 taaagttagt gtattgaaac gtttttatac agtgctaaaa tttgaagtgt agtgcagata
    19321 tatttgtaat agtattatag caattctttg aagaaggtcg agacaagaga aaataggtat
    19381 ctttgagata taagcatgat ttactataaa attattgagt tattcataaa aatttctcta
    19441 tcaaatatca taatgcgtcg tttaaggaga tggttacaat gcaatatagt tgtggaaaaa
    19501 taaatattaa tatccctgat ggatatggag acattaagga tatagtgttt tcggctcata
    19561 ttatagttag gtataataat ggacattgtg gaggtataga tccgcatata attggacttt
    19621 gtaaaaagca gatcagaagg atgtctctat atcctatttt gataatcgta tctagagatt
    19681 caaaggttat tgatgattat aaaaatttag atattgccta tgttgattgt actcaatgtt
    19741 caaataattt tgaaactgcc ttacacgtta aaaat
//
LOCUS       DAVLXH010000039        18971 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00028199
            SAMN33607166-rid17955573.denovo.039, whole genome shotgun sequence.
ACCESSION   DAVLXH010000039 DAVLXH010000000
VERSION     DAVLXH010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607166
            Sequence Read Archive: SRR23725544
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18971)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18971)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721421.1
            Genome Coverage       :: 115x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:42:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,210
            CDSs (total)                      :: 2,161
            Genes (coding)                    :: 2,023
            CDSs (with protein)               :: 2,023
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 73 of 138
            Pseudo Genes (incomplete)         :: 60 of 138
            Pseudo Genes (internal stop)      :: 40 of 138
            Pseudo Genes (multiple problems)  :: 31 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18971
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607166-rid17955573.denovo.039"
                     /strain="AUSMDU00028199"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1349"
     gene            139..792
                     /locus_tag="VYO11_001513"
     CDS             139..792
                     /locus_tag="VYO11_001513"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HEV1596057.1"
                     /translation="MEHSSWHALIKAQLPEGYFGKINQFMEQVYSQGIIYPPKEKVFQ
                     ALLTTLLEEVKVVILGQDPYHGPGQAQGLSFSVPDSIPAPPSLQNILKELSDDIGVKK
                     SHDLTAWAEQGVLLLNACLTVPAGQANGHAGQIWEPFTDAVIQVVNHLDRPVVFVLWG
                     AYARKKKALVTNPHHLIIESAHPSPLSVYRGFWGSKPFSKANAFLKETGQEPIDWLR"
     gene            802..1266
                     /locus_tag="VYO11_001514"
     CDS             802..1266
                     /locus_tag="VYO11_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003012002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEV1596058.1"
                     /translation="MPQLATICYIDNGKELLMLHRNKKPNDVHEGKWIGVGGKLERGE
                     TPQECAVREILEETGLKAKPVLKGVITFPEFTPDLDWYTYVFKVTEFEGDLIDCNEGT
                     LEWVPYDEVLSKPTWEGDHTFVEWLLEDKPFFSAKFVYDGDKLLDTQVDFYE"
     gene            1279..2547
                     /locus_tag="VYO11_001515"
     CDS             1279..2547
                     /locus_tag="VYO11_001515"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HEV1596059.1"
                     /translation="MLLIKNGRVMDPKSGLDQVCDVLVQDGKIIKIAPEITEEGAETI
                     DATGLVVAPGLVDIHVHFREPGQTHKEDIHTGALAAAAGGFTTVVMMANTSPTISDVE
                     TLQAVLQSAAKEKINVKTVATITKNFNGKNLTDFKALLEAGAVGFSDDGIPLESSKIV
                     KEAMEEAKKLNTFISLHEEDPGLNGVLGFNENIAREHFHICGATGVAEYAMMARDVMI
                     AYATKAHVHIQHLSKEESVKVVEFAQGLGAEVTAEVAPQHFSKTEALLLTQGSNAKMN
                     PPLRLESDRRAVIEGLKSGVITVIATDHAPHHVDEKNVEDITKVPSGMTGLETSLSLG
                     LTYLVEAGELSLMELLEKMTYNPAKLYNFEAGYLAENGPADITIFDAKADRLVDSHFA
                     SKAANSPFIGETLKGQVKYTICKGQIVYQA"
     gene            2561..2821
                     /locus_tag="VYO11_001516"
     CDS             2561..2821
                     /locus_tag="VYO11_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1596060.1"
                     /translation="MNYFRKRRERQAKSNSGIYCPSANRSKIQYETKEKADHAVQYDN
                     GGLVRSYYCRTCACWHTTSKSNKPPLSLKNYGLKLFGLDKSE"
     gene            2832..4193
                     /gene="pdrM"
                     /locus_tag="VYO11_001517"
     CDS             2832..4193
                     /gene="pdrM"
                     /locus_tag="VYO11_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-coupled multidrug efflux MATE transporter
                     PdrM"
                     /protein_id="HEV1596061.1"
                     /translation="MYKTKCLREKLVLFLKIFFPILIYQFANYSASFVDTAMTGQYNT
                     MDLAGVSMATSIWNPFFTFLTGIVSALVPIIGHHLGRGKKEEVASDFYQFIYLALGLS
                     VVLLGMVLFLAPTILNHIGLEAAVAAVAVRYLWFLSIGIIPLLLFSVIRSLLDSLGLT
                     KLSMYLMLLLLPLNSGFNYLLIYGAFGVPELGGAGAGLGTSLAYWVLLGISVLVLFKQ
                     EKLKALHLEKRIPLNMDKIKEGVRLGLPIGGTVFAEVAVFSVVGLIMAKFSSLIIASH
                     QSAMNFSSLMYAFPMSISSAMAIVVSYEVGAKRFDDAKTYIGLGRWTALIFAAFTLTF
                     LYIFRGNVASLYGNDPKFIDLTARFLTYSLFFQLADTFAAPLQGILRGYKDTVIPFYL
                     GLLGYWGVAIPVATLFDSLTDFGAYSYWIGLIISLIVSGALYRWRLTVIMKRFESLAK
                     SKR"
     gene            4347..5315
                     /locus_tag="VYO11_001518"
     CDS             4347..5315
                     /locus_tag="VYO11_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent dehydrogenase
                     E1 component subunit alpha"
                     /protein_id="HEV1596062.1"
                     /translation="MSTLDKNLLLEMFRKMEEIRRMDLKIAQLVKKGKVPGMTHFSVG
                     EEAANVGAMLALNPDDLITSNHRGHGQAIAKGIDLNGMMAEILGKYTGTCKGKGGSMH
                     IADLDAGNLGANGIVGGGMGIAVGAALSQQMQNTGKIVVCFFGDGATNEGVFHEAVNM
                     ASIWNLPVIFYCINNGYGISADIKKMTNIEHIHQRSAAYGIPGMFIEDGNNVIDVYEG
                     FQKAVDHVRSGNGPVLIESVTYRWLGHSSSDPGKYRTREEVELWKQKDPIENLRNYLI
                     ENNIASAEELEEIQAQVKEAVEASVKFAEESPFPPLESAFEDIYAD"
     gene            5331..6323
                     /locus_tag="VYO11_001519"
     CDS             5331..6323
                     /locus_tag="VYO11_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000448722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HEV1596063.1"
                     /translation="METKTMSFRDTIILAMSEEMRRDENVFLMGEDVGVFGGDFGTSV
                     GMLEEFDPERVRDCPISEAAISGAAAGAAMTGLRPIVDMTFMDFSVIAMDNIVNQAAK
                     TRYMFGGKGQVPMTVRCAAGNGVGSAAQHSQSLESWFTHIPGLKVVAPGTPADMKGLL
                     KSSIRDNNPVIILEYKSEFNQKGEVPVDPDYTIPLGVGEIKRQGTDVTVVTYGKMLRR
                     VVQAAEELAEEGISVEIVDPRTLVPLDKDIIINSVKKTGKVVLVNDAHKTSGYIGEIS
                     AIISESEAFDYLDAPIRRCAGEDVPMPYAQNLENAMIPTVESIKNAIRKTYNKE"
     gene            6541..7584
                     /locus_tag="VYO11_001520"
     CDS             6541..7584
                     /locus_tag="VYO11_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide acetyltransferase"
                     /protein_id="HEV1596064.1"
                     /translation="MADDKLRATPAARKLADDLGINLYDVSGSGANGRVHKEDVETYK
                     DTNVVRISPLAKRIALEHNIAWQEIQGTGHRGKIMKKDVLALLPENIENDSIKSPAQI
                     EKVEEVPDNVTPYGEIERIPMTPMRKVIAQRMVESYLTAPTFTLNYEVDMTEMLALRK
                     KVLEPIMEATGKKTTVTDLLSLAVVKTLMKHPYINASLTEDGKTIITHNYVNLAMAVG
                     MDNGLMTPVVYNAEKMSLSELVVAFKDIIGRTLDGKLAPSELQNSTFTISNLGMFGVQ
                     SFGPIINQPNSAILGVSSTIEKPVVVNGEIVIRPIMSLGLTIDHRVVDGMAGAKFMKD
                     LKELIETPISMLI"
     gene            7648..9333
                     /gene="lpdA"
                     /locus_tag="VYO11_001521"
     CDS             7648..9333
                     /gene="lpdA"
                     /locus_tag="VYO11_001521"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HEV1596065.1"
                     /translation="MPKAGVDMTEGQIVQWNKKVGEFVKEGEILLEIMTDKVSMELEA
                     EENGYLIAILKGDGETVPVTEVIGYLGEERENIPTAGAASPEASPVPVASTSNDDGKS
                     DDAFDIVVIGGGPAGYVAAIKAAQLGGKVALVEKSELGGTCLNRGCIPTKTYLHNAEI
                     IENIGHAANRGIVIENPNFTVDMEKLLETKSKVVNTLVGGVAGLLRSYGVTVHKGIGT
                     ITKDKNVLVNGSELLETKKIILAGGSKVSKINVSGMESSLVMTSDDILEMNEVPESLV
                     IIGGGVVGIELGQAFMTFGSKVTVIEMMDRIVPAMDAEVSKNLRLILERKGMTILTGT
                     KLQEIIEENGQLRIKVEGKDDIIASKALLSIGRMPDLEGIGEVEFELDRGCIKVNEYM
                     ETSVPGIYAPGDINGTKMLAHAAFRMGEVAAENALKGNHAVAKLNLTPAAIYTLPEVA
                     AVGLTEEQAREKYDVAIGKFNFAANGRAIASDAAQGFVKVIADKKYGEILGVHIIGPA
                     AAELINEASSIIEMEITVEEMLKTIHGHPTYSEVMYEAFADVLGMAIHSPKKK"
     gene            9397..10386
                     /locus_tag="VYO11_001522"
     CDS             9397..10386
                     /locus_tag="VYO11_001522"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000873976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HEV1596066.1"
                     /translation="MKYIINHSNDTAFNIALEEYAFKHLLDEDQIFLLWINKPSIIVG
                     RHQNTIEEINRDYVRENGIEVVRRISGGGAVYHDLNNLNYTIISKEDENKAFDFKSFS
                     TPVINTLAQLGVKAEFTGRNDLEIDGKKFCGNAQAYINGRIMHHGCLLFDVDLSVLAN
                     ALKVSKDKFESKGVKSVRARVTNIINELPKKITVEKFRDLLLEYMKKEYPEMTEYVFS
                     EEELAEINHIKDTKFGTWDWNYGKSPEFNVRRGTKFTSGKVEVFANVTESKIQDIKIY
                     GDFFGIEDVAAVEDALRGVKYEREDVLKALKTIDITRYFAGISREEIAEAVVG"
     gene            complement(10459..11529)
                     /gene="xerS"
                     /locus_tag="VYO11_001523"
     CDS             complement(10459..11529)
                     /gene="xerS"
                     /locus_tag="VYO11_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000817875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HEV1596067.1"
                     /translation="MKREILLERIDKLKQLMPWYVLEYYQSKLAVPYSFTTLYEYLKE
                     YDRFFSWVLESGISNADKISDIPLSVLENMSKKDMESFILYLRERPLLNANTTKQGVS
                     QTTINRTLSALSSLYKYLTEEVENDQGEPYFYRNVMKKVSTKKKKETLAARAENIKQK
                     LFLGDETAGFLTYIDQEHPQQLSNRALSSFNKNKERDLAIIALLLASGVRLSEAVNLD
                     LRDLNLKMMVIDVTRKGGKRDSVNVAAFAKPYLENYLAIRNQRYKTEKTDTALFLTLY
                     RGVPNRIDASSVEKMVAKYSEDFKVRVTPHKLRHTLATRLYDATKSQVLVSHQLGHAS
                     TQVTDLYTHIVNDEQKNALDSL"
     gene            complement(12113..13663)
                     /locus_tag="VYO11_001524"
     CDS             complement(12113..13663)
                     /locus_tag="VYO11_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HEV1596068.1"
                     /translation="MEEQSEIVRSKKEFAFASSTILSQVGRGIIVGLIVGIIVGSFRF
                     LIEKGFHLIQGVYQDQGYLVRNLFVLVLFYILICWLSAKLTRSEKDIKGSGIPQVEAE
                     LKGLMSLNWWGILWKKYVLGILAIASGLMLGREGPSIQLGAVGGKGIAKWLKSSPVEE
                     RSLIASGAAAGLAAAFNAPIAALLFVVEEVYHHFSRFFWVSTLAASIVANFVSLLMFG
                     LTPVLDMPDNIPPMTLDQYWIYLVMGIFLGFSGFLYEKAVLNVGRVYDLIGQKIHLDR
                     AYYPILAFILIIPVGIFLPQIIGGGNQLVLSLTEQNFSFQVLLAYFLIRFIWSMISYG
                     SGLPGGIFLPILALGSLLGALVGVICVNLGLVSQEQFPIFVILGMSGYFGAISKAPLT
                     AMILVTEMVGDIRNLMPLGLVTLVSYIIMDLLKGTPVYEAMLEKMLPEEVSSEGEVTL
                     IEIPVSDKIAGKQVHELNLPHNVLITTQVHNGKSQTVNGSTRMYLGDMIHLVIPKSEI
                     GKVKDLLL"
     gene            complement(13679..14458)
                     /locus_tag="VYO11_001525"
     CDS             complement(13679..14458)
                     /locus_tag="VYO11_001525"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HEV1596069.1"
                     /translation="MATIKEIKELLVTVKELESPIFLELEKDNRSGVQKEISKRKRAI
                     QAELDENLRLESMLSYEKELYKQGLTLIAGIDEVGRGPLAGPVVAAAVILPKNCKIKG
                     LNDSKKIPKKKHLEIFQAVQDQALSIGIGIIDNQVIDQVNIYEATKLAMQEAISQLSP
                     QPEHLLIDAMKLDLPISQTSIIKGDANSLSIAAASIVAKVTRDELMKEYDQQFPGYDF
                     ATNAGYGTAKHLEGLTKLGVTPIHRTSFEPVKSLVLGKKES"
     gene            complement(14445..15296)
                     /gene="ylqF"
                     /locus_tag="VYO11_001526"
     CDS             complement(14445..15296)
                     /gene="ylqF"
                     /locus_tag="VYO11_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HEV1596070.1"
                     /translation="MATIQWFPGHMSKARRQVQENLKFVDFVTILVDARLPLSSQNPM
                     LTKIVGDKPKLLILNKADLADPAMTKEWRQYFESQEIQTLAINSKEQVTVKVVTDAAK
                     KLMADKIARQKERGIQIETLRTMIIGIPNAGKSTLMNRLAGKKIAVVGNKPGVTKGQQ
                     WLKTNKDLEILDTPGILWPKFEDETVALKLALTGAIKDQLLPMDEVTIFGINYFKEHY
                     PEKLAERFKQMKIEEEAPVIIMDMTRALGFRDDYDRFYSLFVKEVRDGKLGNYTLDTL
                     EDLDGND"
     gene            complement(15378..16844)
                     /locus_tag="VYO11_001527"
     CDS             complement(15378..16844)
                     /locus_tag="VYO11_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000291919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEV1596071.1"
                     /translation="MYYVTKTNSKGQPLYQVVEKCKDPLTDKWRTVTVSYTRNTSRAR
                     KQAEREVMDKIEKLTSSLESQYNPEMITTFGELKESWFQTWCVSVKPQTIKREELVIE
                     RLGKIIGDEFLLDRITPLLMKNCLNKYLDKYDASPSTMTHIKSTCNKIFNHGVLYNVI
                     KYSPMTAVKIDVPLEKKREARKRLDAKFLEIHELQAFFDVLGQCRNASYYDLAIVLLL
                     TGIRIGEAAFLPSDVDFDKGILHIDKALQYHDLKVDEFYFDTTKTVNADREVALPIAA
                     SEAIQRAIKRNQEFEAYMEQNPSPAFKKCDSVFQTEYGSPITSHSFRQVLKRVEWVKH
                     VTPHSFRHMHISYLQSNEMHIAVKDIMTRVGHANFETTMGYTHNISRSQENTVTALNQ
                     FVEKHNFHFKELKSYTCKYSRMIEQFIETCDDNNKVELSVDEFKDLLHLGSRYSPKHI
                     VSNLLLKIKKDIVKYHPQFDIKIVKLSENQIKGFSISW"
     gene            complement(16920..17153)
                     /locus_tag="VYO11_001528"
     CDS             complement(16920..17153)
                     /locus_tag="VYO11_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000693750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEV1596072.1"
                     /translation="MEIKYVSVENSVAEWADKKSILKRWEGLNLYTLNRWIKEMRENK
                     RFSLYVINPTHKLVFINLEGFECFLRWKQKRTK"
     gene            complement(17455..17678)
                     /locus_tag="VYO11_001529"
                     /pseudo
     CDS             complement(17455..17678)
                     /locus_tag="VYO11_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285460.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            complement(17935..18408)
                     /gene="tnpA"
                     /locus_tag="VYO11_001530"
     CDS             complement(17935..18408)
                     /gene="tnpA"
                     /locus_tag="VYO11_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605-like element ISSpn6 family
                     transposase"
                     /protein_id="HEV1596073.1"
                     /translation="MREDNQSLSHTTWNCKYHIVFAPKYRRQIIYGRYKASIGRIIRD
                     LCERKGVIIHEANACSDHIHMLISIPPKLSVLSFMGYLKGKSSLMIFDKHANLKYKYG
                     NRKFWCRGYYVDTVGRNQKVIAEYIQNQLQEDRVADQLTLFESVDPFTGEINKRK"
     gene            complement(18566..>18971)
                     /locus_tag="VYO11_001531"
     CDS             complement(18566..>18971)
                     /locus_tag="VYO11_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1596074.1"
                     /translation="IIYIITLAFEINIAMDRFFYTVLLSIVVLLFWDSLAILLTMFIN
                     DYRRRDIVIRFVLTPLGFTAPVFYLIDSAPSIVRWIGQLNPLTYQLTILRNFYFKNST
                     TLELVFLLLTSLLVLISVSFIIPKIKLILIER"
BASE COUNT         5669 a         3658 c         3897 g         5747 t
ORIGIN      
        1 tagccagtct ttataaactg tattcacgta ttcaaatcgt atatagtcga tttattaaat
       61 ctttagataa attgtaaaaa gtggtttcca tagccacttt ttgctataat agaggcagta
      121 aaaatgaagg agtcagctat ggaacactcg tcttggcatg ctttgattaa ggcgcaatta
      181 cctgagggtt atttcgggaa aatcaatcag tttatggagc aggtctattc tcaggggatt
      241 atttatccac ccaaggaaaa ggtttttcag gctctcttga caacactgct tgaagaagtt
      301 aaggtggtaa ttctagggca agacccctat cacggaccag gtcaagcgca gggcttgagt
      361 ttttctgtac ctgactctat cccagctcca ccatccttgc aaaatatctt gaaagaattg
      421 tcagatgata tcggagttaa gaaatctcat gatttgacag cttgggctga gcaaggagtc
      481 ttgcttctta atgcttgttt gactgttcct gctggacagg ccaatggtca tgctggtcaa
      541 atctgggagc cttttactga tgctgtgatt caggtggtca atcatctaga tagaccagtc
      601 gtttttgtac tctggggagc ttatgcacgt aagaagaagg ccttagttac caatcctcat
      661 cacttgatta tcgaatcagc ccatccaagt cctttgtcgg tttatagagg attttggggt
      721 tccaagccct tttccaaggc caatgcattc ttaaaagaga caggacaaga accaatcgat
      781 tggcttagat aaggagaaaa tatgcctcag ttagcgacga tttgctacat tgataatggg
      841 aaagaactgc tcatgctcca tcgtaataag aaacccaatg atgtccatga agggaaatgg
      901 attggtgtgg gtggtaagct agagagagga gagacgcccc aggaatgcgc ggtgcgtgaa
      961 atccttgaag aaacagggct caaagccaag ccagttctaa aaggtgtcat cacttttcct
     1021 gaatttacac cagatttaga ctggtacacc tatgttttta aggtgacgga gtttgagggc
     1081 gacttgattg actgcaatga ggggacgcta gaatgggttc cctatgatga ggttttgagc
     1141 aagccgactt gggaaggtga ccacaccttt gttgagtggc ttttagagga taaacccttc
     1201 ttttcagcca agtttgttta tgatggggat aaattgttgg atacccaagt tgatttctat
     1261 gaataaagga gaaagcagat gctactaatc aaaaatggtc gtgtaatgga tcctaagtct
     1321 ggtttggatc aagtttgtga tgtcttagtt caagatggga aaattatcaa aattgcgcct
     1381 gagatcacgg aagaaggagc agaaacgatt gatgctactg gtcttgtggt tgctcctggt
     1441 ttggtcgata ttcatgtgca tttccgtgaa cctggtcaaa cacataaaga agacattcat
     1501 actggtgccc tagcagccgc tgcaggtggt tttactactg tcgtcatgat ggctaatacc
     1561 agtccaacca tttcagacgt ggagactttg caagcagtcc tccagtcagc tgccaaagag
     1621 aagattaatg tcaagacagt tgcgaccatt actaaaaact ttaatggtaa aaacttgact
     1681 gactttaagg cacttttaga agctggtgcg gttggtttct ctgatgacgg tattccgctt
     1741 gagagcagta agattgtcaa ggaagccatg gaggaagcca aaaaactcaa tacctttatc
     1801 agccttcatg aggaagatcc aggtttgaac ggtgttcttg gctttaatga aaatattgct
     1861 agagaacatt tccatatctg cggtgctact ggggtggctg agtacgctat gatggcgcgt
     1921 gatgtcatga ttgcctatgc aactaaagcc catgttcaca tccagcattt gtctaaggaa
     1981 gaaagtgtta aagtagtgga gtttgctcag gggttaggtg cagaagtcac agcagaagta
     2041 gcgccacagc atttctctaa gacagaagca cttcttttaa cacaaggtag caatgctaag
     2101 atgaatccac cgcttcgttt ggaatcagac cgtcgtgccg ttatcgaagg tctcaaatca
     2161 ggtgtcatca cagttattgc gactgaccac gcgcctcatc atgtagatga aaaaaatgtt
     2221 gaggatatta ccaaagtacc atctggtatg actggcttag aaacatccct gtctctcggc
     2281 ttgacctatt tagtagaagc tggtgagttg agcttgatgg aattacttga aaaaatgaca
     2341 tacaacccag ccaagcttta caactttgaa gcaggttact tggctgagaa tggtccagca
     2401 gatatcacta tttttgatgc caaggctgac cgccttgtgg actcccattt tgcttccaaa
     2461 gcagctaatt caccattcat cggtgaaacc ttaaaagggc aggttaaata taccatctgt
     2521 aagggacaaa tcgtctatca agcttgatag gagttagaat atgaattatt ttcgaaaacg
     2581 tagggagaga caagcgaaat ctaatagtgg aatttactgt ccctcagcta atcgttccaa
     2641 aattcaatat gaaactaaag aaaaagctga ccatgcggtt caatatgata acggaggttt
     2701 agttagaagc tattattgtc gtacatgtgc gtgttggcat actacttcaa aatctaataa
     2761 acctccgcta agtttgaaaa actatggtct gaaactcttt ggtttagata aatcagaata
     2821 gaaagagaag tatgtataag acaaagtgtt tacgagagaa gttagtatta tttttaaaaa
     2881 ttttcttccc aatcctgatc taccaatttg ccaattattc tgcctctttt gttgatactg
     2941 caatgacagg tcaatacaac actatggact tggctggtgt atctatggca accagtatct
     3001 ggaatccttt ctttacattt ctaacaggga ttgtgtcagc cttggtgcct atcattggtc
     3061 accatcttgg tcgaggcaaa aaggaagaag ttgcgtctga tttttaccaa tttatttatt
     3121 tggccttggg cctatctgtg gtcttgctgg ggatggtact tttcttggca ccaacaatct
     3181 tgaatcatat tgggttagaa gcagcagtag cggcagtagc ggttcgctat ctttggtttt
     3241 tatctatcgg gattatcccc ttgttgctct ttagcgtcat tcgttccttg ctggattcgc
     3301 tgggcttgac caaactgtcc atgtacctca tgcttttgtt actccctctc aatagcggat
     3361 ttaactatct cttgatttac ggtgcctttg gtgttccaga actgggaggg gctggtgctg
     3421 gtttaggaac atccttggcc tactgggtct tgcttgggat ttctgttctg gttttattta
     3481 aacaggagaa gctcaaagcc ttacaccttg agaaacgaat tccacttaat atggataaaa
     3541 ttaaggaagg agttcgttta ggtctgccta ttgggggaac tgtcttcgcg gaagtggctg
     3601 tcttttcagt ggttggcttg attatggcta agttttcgtc cttgattata gctagtcacc
     3661 agtcagctat gaacttttca agtcttatgt acgcctttcc tatgagtatc tcatcggcta
     3721 tggctattgt cgtttcctat gaagtgggag ccaagcgatt tgatgatgcg aaaacctata
     3781 ttggtctagg aagatggact gccctcattt ttgcggcctt caccttaacc ttcctttaca
     3841 tttttagggg aaatgtggcc agtctttatg gtaacgaccc aaaatttatc gatttgacag
     3901 cgcgtttttt aacttatagt cttttcttcc agttagcaga tacctttgcg gcgccgcttc
     3961 agggaatttt gcgggggtat aaggatacag ttattccttt ttaccttggt ttgcttggtt
     4021 attggggcgt agcaatccct gtggctacgc tatttgattc cctaacagat tttggagctt
     4081 attcttactg gatcggcttg attattagtt tgattgtgag tggggcgctc taccgttggc
     4141 gtttaactgt gattatgaag agatttgaat ctttagcaaa atccaaacgc taaaaagttt
     4201 gtgaaaaaat atccttgaca agaaaatccc ttgttttcac ggggttttct tttttatttt
     4261 gtgaaatttc ttttagaaaa actttgacag tatttgccaa aagcggtaaa atagtaaggt
     4321 aagaagaaag ttagaaaggc aagaagatgt caactttaga taaaaatctt ttgctagaaa
     4381 tgttccgtaa gatggaagaa atccgtcgca tggacttaaa aattgcacaa ttagtaaaga
     4441 aagggaaagt gccaggaatg acgcactttt ctgttggtga agaggcagct aacgtggggg
     4501 ctatgttagc tctcaatcca gatgatctga ttacctcaaa ccaccgtgga cacgggcaag
     4561 ctattgctaa agggattgac ctcaacggaa tgatggctga aatccttggt aaatacactg
     4621 gaacctgtaa agggaaaggt ggatctatgc atatcgctga ccttgatgct gggaaccttg
     4681 gtgccaatgg tatcgtaggt ggtggtatgg ggatcgctgt cggtgcagcc ctcagtcagc
     4741 aaatgcaaaa taccggtaaa atcgttgtct gcttctttgg agatggtgcg accaatgaag
     4801 gtgttttcca cgaagcagtg aacatggctt ctatctggaa cctgccagtc attttctatt
     4861 gcattaacaa cggttacggt atctctgcgg atatcaagaa aatgaccaat atagaacata
     4921 tccatcaacg tagcgccgct tatggaattc ctggaatgtt catcgaagat ggtaacaatg
     4981 tcatcgatgt ctatgaagga tttcagaaag ctgtggacca tgttcgcagt ggcaatggtc
     5041 cagtcttgat tgaaagtgta acttatcgct ggctcggtca ctcatcatct gaccctggta
     5101 aatatcgtac gcgtgaagaa gtggaattgt ggaaacaaaa agatccaatc gaaaacctcc
     5161 gcaattacct tattgaaaat aacattgcaa gtgccgaaga attggaagaa atccaagcgc
     5221 aagtaaagga agcagtagaa gcttctgtta aatttgcaga ggaaagccca ttcccaccgc
     5281 ttgaatcagc ctttgaagat atttacgcag actaaggaga aagagataaa atggaaacaa
     5341 aaacaatgtc cttccgtgac accattatcc ttgctatgtc tgaggaaatg cgtcgcgatg
     5401 aaaatgtgtt cttgatggga gaagacgtcg gtgtcttcgg aggagacttc ggtacttctg
     5461 ttggaatgct tgaagaattt gatccagaac gtgtccgtga ctgtccgatt tctgaagctg
     5521 ccatctctgg agcagcagca ggagcagcca tgacaggact tcgtccaatc gtcgatatga
     5581 ccttcatgga cttctctgtt attgccatgg acaatatcgt caaccaagct gctaaaacac
     5641 gttacatgtt tggtggtaaa ggtcaggttc caatgactgt tcgttgtgca gctggtaacg
     5701 gagttggctc tgccgcccag cactcacaat ctctagagtc ttggtttact cacattccag
     5761 gacttaaggt tgtggcacct ggaacacctg cggacatgaa aggcctgctt aagtcttcta
     5821 tccgtgataa caacccagtt attatacttg agtacaagtc agaatttaac caaaaagggg
     5881 aagtgccagt tgatccagac tacacaattc cacttggggt tggtgaaatc aaacgccaag
     5941 gaacggatgt aacagttgtt acttatggaa aaatgcttcg ccgtgtggtt caagctgctg
     6001 aagaattagc agaagaagga atttcagttg aaattgttga cccacgtacc cttgttccgc
     6061 ttgataagga tatcatcata aactcagtga agaagactgg taaggttgtt ctggtcaacg
     6121 atgcccacaa aacaagtggc tatatcggtg aaatttcagc tattatttca gaatcagaag
     6181 catttgacta tctagatgca ccaattcgcc gttgtgcagg agaagatgtg ccgatgcctt
     6241 atgcacaaaa cctagaaaat gcaatgattc caacagttga aagtatcaaa aatgcaatcc
     6301 gaaaaactta taacaaagaa tagagttaca taagataagt tatgtaaata aaataaagct
     6361 gacgagaaac tttgtatctt ttaggtgcag agctcttcgt cattaatatc ttagattaga
     6421 gcacgggcta aaagctcgga aaaaagataa atctccttgg cttcatcgaa gccatcgtcg
     6481 atttcctatt tttcagtcgc ttttgacgcc ctttgtatca taaatagaat tggagaggtc
     6541 atggctgatg acaagctaag agcgactcct gcagctagaa agttagcgga tgatttaggg
     6601 ataaacctct acgacgtttc tggctcaggt gcaaacggtc gtgtccacaa agaagacgtg
     6661 gaaacttata aagacacaaa cgtggttcgc atttcgccac ttgcaaaacg aattgccctc
     6721 gaacataaca ttgcttggca ggaaatccaa ggaaccggtc atcgtggtaa aatcatgaag
     6781 aaggatgttt tggccctgct tcctgaaaat atcgaaaacg atagcatcaa atctcctgct
     6841 cagattgaaa aagtggaaga agtccctgat aacgtaacac catatggtga aatcgagcgt
     6901 attccaatga caccaatgcg taaggttatt gcccaacgca tggttgaatc ttacttgact
     6961 gcgccaacct tcaccctcaa ctatgaagtt gatatgactg aaatgttggc tcttcgtaag
     7021 aaggttcttg agccaatcat ggaagcaact gggaagaaga ctactgtaac agaccttctt
     7081 tcgcttgcag ttgttaagac tcttatgaaa cacccataca tcaatgcttc attgacagaa
     7141 gatggcaaga ctattatcac tcacaactat gtcaatcttg ccatggcagt tgggatggat
     7201 aatggattga tgacacctgt tgtttacaat gctgagaaga tgagtctttc agaactggtt
     7261 gtagccttta aggatattat tggccgtacc ttggatggta aattggctcc aagtgagtta
     7321 caaaattcaa cattcacaat cagtaatttg ggaatgtttg gtgttcagtc ctttggcccg
     7381 attattaacc aacccaactc agctatcctt ggtgtcagtt cgacaatcga gaagccagtt
     7441 gtcgtcaatg gtgaaattgt gattcgccca atcatgagtt taggattaac cattgaccac
     7501 cgtgtcgtag atggtatggc tggtgctaag tttatgaagg acttgaaaga gttgattgaa
     7561 acgccaatct caatgttaat ttaagagcaa gagtattcat ttttaagata tagataaagg
     7621 aaggaagaca tggccttaga agtaattatg ccaaaagccg gcgtggatat gacagaagga
     7681 caaatcgtcc aatggaataa aaaagtcgga gaatttgtaa aagaaggaga aatccttttg
     7741 gaaatcatga ctgataaagt cagcatggaa ttggaagccg aagaaaatgg atacttgatt
     7801 gccattctca aaggagatgg tgaaactgtc cctgtaacgg aagttatcgg ttaccttggt
     7861 gaagaaaggg aaaacatccc aacagctgga gcagcatcgc cagaagctag ccctgtacct
     7921 gtagcaagta cctcaaacga tgatggtaag agcgatgatg cttttgatat cgttgtgatt
     7981 ggtggaggtc ctgctggtta tgttgcagcc attaaagctg cccaactcgg cggtaaggtt
     8041 gcccttgttg agaaatctga acttggtgga acctgcttaa accgtggatg tattccaacc
     8101 aagacctacc ttcataacgc tgaaattatt gaaaatatcg gtcatgctgc aaatcgtggt
     8161 atcgtgattg aaaatcctaa cttcactgtt gatatggaaa aacttttaga aactaaatct
     8221 aaagttgtta atactcttgt tggtggtgtt gcaggacttc ttcgtagcta cggagttact
     8281 gttcataaag gaattggtac aatcactaaa gacaagaacg tcttggtaaa tggttctgaa
     8341 ttgcttgaaa ccaagaaaat cattcttgct ggtggttcaa aagtcagcaa gatcaacgtc
     8401 tctggtatgg aatcttcact tgtcatgact agtgatgaca ttcttgaaat gaacgaagtg
     8461 ccagaaagcc ttgttatcat cggtggtgga gttgtcggta tcgaactcgg tcaggccttc
     8521 atgacatttg gttcaaaagt gactgttatc gaaatgatgg accgtatagt tccagctatg
     8581 gatgcggaag tttctaagaa ccttcgcttg atccttgagc gtaaaggaat gaccatcttg
     8641 actggtacta aactgcaaga aatcattgag gaaaatggtc aacttcgtat caaggttgaa
     8701 ggaaaagacg atatcatcgc aagcaaagct cttctttcaa ttggtcgtat gccagacctt
     8761 gaaggtattg gagaggttga gtttgaattg gatcgtggtt gtatcaaggt caacgaatac
     8821 atggaaactt cagttccagg catttatgca ccaggtgaca tcaacggtac taagatgttg
     8881 gctcacgcag ctttccgcat gggtgaagtt gccgctgaaa atgcccttaa aggaaatcat
     8941 gcagttgcca aattgaattt gactcctgca gccatctaca ctctccctga agtagcagca
     9001 gtaggtttga cagaagaaca agcccgtgag aaatacgatg ttgccatcgg taagtttaac
     9061 tttgctgcta acggtcgtgc tattgcatct gacgcagctc aaggtttcgt aaaagttatc
     9121 gctgataaga aatacggaga aatccttggt gtacacatta ttggtcctgc agccgcagaa
     9181 ttaataaacg aagcatcaag catcatcgaa atggaaatca ctgttgagga aatgctgaag
     9241 accatccacg ggcacccaac ttactctgaa gtgatgtacg aagcgtttgc agatgttcta
     9301 ggaatggcca tccattcacc taagaaaaaa taaaacgaag atagattaga ctggaaggtt
     9361 atttccagtt tctatcatat aaagtaaagg gatatcatga aatacattat caatcattca
     9421 aatgacactg cttttaatat tgccttggaa gaatacgcct ttaaacacct tttggatgag
     9481 gatcaaatct tcctactttg gattaacaag ccatctatca ttgttggtcg tcaccagaac
     9541 actatcgaag aaatcaaccg tgattatgtt cgcgaaaatg gtattgaggt agttcgccgt
     9601 attagtggtg gtggagctgt ttaccacgat ttaaataacc tcaactacac gatcatctcc
     9661 aaagaagatg aaaataaggc atttgacttc aagagcttct caactccggt tatcaatacc
     9721 ctggctcaac tcggggttaa agctgagttc acaggtcgta atgaccttga gattgatggt
     9781 aagaagttct gtggcaatgc ccaagcctat atcaacggcc gtatcatgca ccacggttgc
     9841 ttgctctttg acgttgattt gtcagtcctc gcaaatgccc ttaaggtttc aaaagataaa
     9901 tttgaatcaa aaggtgtgaa atccgtccgt gcccgtgtaa ctaatattat caatgaatta
     9961 ccaaaaaaaa tcacagtcga aaaattccgt gatttactct tggaatacat gaaaaaagag
    10021 tacccagaga tgactgaata cgtcttttca gaagaagaat tggccgaaat caatcacatc
    10081 aaggatacta agtttggaac ttgggactgg aactatggta aatcacctga atttaacgtc
    10141 cgtcgtggaa ccaaattcac tagtggtaag gttgaagtct ttgctaacgt tactgaatca
    10201 aaaatccaag acatcaagat ttatggtgac ttctttggta ttgaagacgt tgctgcagta
    10261 gaagatgccc ttcgtggggt gaaatacgaa cgcgaagatg ttcttaaggc gctaaaaacc
    10321 attgatatca cacgctactt cgctggtatt agccgtgaag aaatcgctga agcggtagtt
    10381 ggataaatca aaaagaagtt ggccaactaa ccaacttctt tttttgatat ttatttacat
    10441 aatttaaaat acgtaaaatt ataaactatc tagagcattc ttttgttcat cattaacaat
    10501 atgggtatag aggtcagtga cttgtgtgct agcatgtcct agttggtgac tgactaaaac
    10561 ttgtgattta gttgcatcat agagcctagt tgctagtgta tggcgcagtt tatggggtgt
    10621 tacacgcact ttaaaatcct ctgagtattt agcaaccatt ttctcaacgc tagaagcatc
    10681 gatacgatta ggaacacctc tgtagagagt taaaaaaagg gctgtatctg ttttttccgt
    10741 tttatagcgt tgattccgaa tggccagata attctctaaa taaggtttag caaaagcagc
    10801 gacattgact gagtcacgtt tgccaccttt tcgagtaaca tcaataacca tcatttttag
    10861 attgagatct cttagatcta gattaacagc ttcagataag cgaacaccag atgccaagag
    10921 aagggcaata atggctaaat ctcgttcttt atttttgttg aatgatgaga gagctcgatt
    10981 tgaaagctgt tgtgggtgct cttgatcgat ataagttaga aaacctgctg tttcatcacc
    11041 tagaaagagt ttttgcttga tattttcagc tctggcagca agggtttctt tctttttctt
    11101 ggttgaaact tttttcatta cattacgata gaaataaggt tccccctgat cattttcaac
    11161 ctcctcggtt agatacttgt aaagactaga aagtgctgat aaggttcgat tgatagttgt
    11221 ctgtgaaaca ccttgttttg ttgtattagc attcagcaag ggacgttcac gtagataaag
    11281 gataaaggat tccatgtctt tcttagacat attttccaaa actgataaag gaatatcgga
    11341 tattttatca gcgtttgaaa taccagactc caaaacccag ctgaaaaatc ggtcatattc
    11401 cttaaggtat tcgtacaggg ttgtaaaact gtagggcaca gccagcttag attggtagta
    11461 ttccagaaca taccagggca tgagttgttt tagtttgtca attcgttcca gtaaaatctc
    11521 acgtttcatg tattttctcc ataagtaagt atactagtag tatagcatag acttgtatat
    11581 ttttcaagaa aattatagtt tttcagaaag atgttatagg agtttttcaa agtgataaaa
    11641 agacttagac ctacaaacaa aacagaataa ggaaaataat aaaaatctca cccactaaac
    11701 ttctgttaat actacataac tgaagagcta tataaggagc tatgagatac aaaacacatt
    11761 gtataataga ttgaaactag aatagtacat ctggacttct aaaacattgc tagaaattga
    11821 tttgattgtc ctgattgttt tatcctattt ctatttcatt tcactatata attgctattg
    11881 ttttcttttt catgatttta atcttactgt acagatttga tacagtaaac tcctttccag
    11941 ctttatgctt tatcatttct aacttaatta tagtcttatt tttaataaag ttcaattatt
    12001 tatatgtaaa attcctcatc agtaaaaaat aaccgatctc atttctgaga atcggttttc
    12061 taaataaatc aagctgagtg tttacataac ataaattatg tgaatgatca tgctacaaca
    12121 acaaatcttt gacttttcca atttcacttt ttggaataac caggtgaatc atatcaccca
    12181 gatacattct ggttgagccg ttaactgttt ggctcttgcc attatggact tgagttgtga
    12241 tgaggacgtt gtgtggtaag ttgagttcat gaacttgttt cccagcaatt ttatcagaaa
    12301 ctggtatttc gataagtgta acttctcctt cgctagatac ttcttctgga agcatttttt
    12361 ccagcatggc ttcatagact ggcgtacctt tgagcaaatc catgataata taagaaacaa
    12421 gagtgacaag accaagtggc atgaggttgc gaatatctcc taccatctca gttacgagga
    12481 tcatagcggt taagggagct tttgatatgg ctccaaaata gccactcatt cctagaatga
    12541 caaatatagg gaattgctct tgactgacaa gtccaagatt gacacagata acaccaacta
    12601 aggcaccaag caaagaacca agagctaaaa tggggaggaa aattcctcct ggcagtccac
    12661 ttccatagct aatcatactc caaataaagc ggatcaaaaa gtaagctaat aaaacttgga
    12721 aactaaaatt ttgttcagtt aaagaaagga caagctgatt tccgccacca atgatttgag
    12781 gtaagaagat tccgactggt atgataagga taaaagccaa gatgggataa taagctctat
    12841 ccaaatggat tttttgacca atcaagtcat aaactcttcc aacgtttaat acagctttct
    12901 catagagaaa gcctgaaaat ccaaggaaaa ttcccatgac gagatatatc caatactgat
    12961 ctagggtcat gggaggaatg ttatctggca tatccaatac tggtgtcaaa ccgaacatga
    13021 gtagagacac aaagtttgct acgatgctgg ctgctagagt tgagacccag aaaaagcgcg
    13081 aaaaatggtg atagacttct tctacaacaa agagaagtgc tgcaatagga gcattaaagg
    13141 ctgcggctaa acctgctgca gctccactgg caatcaagga acgttcctct actggactgg
    13201 atttgagcca cttggcaatt cctttaccac caactgctcc aagttgaata ctgggtccct
    13261 ctcgacccag catgagtcca ctggcaatag caagaatacc tagcacatat tttttccaaa
    13321 gaatgcccca ccagttgagg gacatgaggc ctttcagttc ggcttcgact tgaggaattc
    13381 ctgagccttt aatatctttt tctgaccgtg ttagtttggc actgagccaa cagatgagta
    13441 tataaaacaa aaccagtaca aaaagattgc gcactaagta cccttgatct tgataaactc
    13501 cttgtatcag gtggaagcct ttttcaatta agaaacgaaa ggatccgacg ataattccaa
    13561 cgatgaggcc gacaatgatt cctcgaccaa cttgggatag tatagtgctg gatgcaaagg
    13621 cgaattcttt cttagaacgg actatttccg actgttcctc catggtattt cctttcaatt
    13681 aactttcttt tttacctaaa accagtgatt taacgggttc aaagctggtt cggtgaattg
    13741 gggtaactcc tagttttgtg aggccttcca gatgtttagc tgtgccatat cctgcattag
    13801 tagcgaaatc atagccaggg aactgctgat cgtattcttt catcaattca tcacgtgtta
    13861 ccttggctac tatagatgct gctgcgatag agagggagtt ggcatctcct ttgataatgg
    13921 aggtttgtga aatgggcaag tccagtttca tggcatcaat caaaaggtgc tctggttgag
    13981 ggctgagctg ggagattgct tcttgcatgg ctagtttggt tgcttcatag atgttgactt
    14041 ggtcgatgac ctgattatct atgatgccaa ttccaatcga caaggcttgg tcttgaacgg
    14101 cttggaaaat ctccagatgt ttctttttag gaattttctt gctgtcgttg agacctttaa
    14161 tcttacaatt tttaggtaaa ataacggccg cagcgactac aggaccagca agaggaccac
    14221 gaccaacctc atcaatacct gcaattaagg tcaatccttg cttataaagt tctttttcat
    14281 aagaaagcat ggattccaag cgcaaatttt catctaattc agcttgaatg gctcttttac
    14341 gcttgctgat ttccttttga actcctgagc gattatcctt ttcaagctct aaaaaaatag
    14401 ggctttctaa ctccttgact gtcacaagga gttctttgat ttctttaatc gttgccatcg
    14461 aggtcttcca atgtatctaa ggtatagtta ccgagtttgc catcacggac ttccttcacg
    14521 aagagactgt aaaaacggtc atagtcatca cggaaaccga gggcgcgggt catatccata
    14581 ataatcacag gcgcttcttc ttcaattttc atttgtttga agcgttcagc cagcttttct
    14641 ggataatgtt ctttgaaata attgatacca aaaatggtaa cctcatccat aggaagcaac
    14701 tgatccttga tagctccagt caatgccaac ttaagtgcaa cagtttcatc ctcaaactta
    14761 ggccagagaa tccccggtgt atccaagatt tccagatctt tattggtttt aagccattgt
    14821 tgaccttttg tgacccctgg cttgtttcca acaacagcaa tctttttacc agccaaacgg
    14881 ttcatcagag ttgatttacc agcgtttgga atcccgataa tcatggtacg caaggtttca
    14941 atctgaatcc cacgttcttt ctggcgagca atcttatcag ccatgagctt cttggccgca
    15001 tctgttacaa cttttacagt cacttgctct ttggagttga tagctagcgt ctggatttct
    15061 tgtgattcaa aatactgacg ccattccttg gtcattgctg gatcagccaa gtcggccttg
    15121 tttaaaatca agagttttgg tttatcacca acaatcttgg tcaacatagg attttgacta
    15181 gatagaggca agcgtgcatc tactaaaatc gtcacaaaat caacaaattt taaattttcc
    15241 tgcacctgtc gacgagcttt agacatgtga ccaggaaacc attgaatagt agccattgca
    15301 tttttttcct ttcgtagcaa gggtttagca cccctcattt attttactat cgtctaaaca
    15361 ccaagcgaac accaaaacta ccacgaaatg gaaaaacctt tgatttgatt ctcgcttaat
    15421 ttcacaatct ttatatcaaa ctgtgggtga tatttgacaa tatctttttt gatttttaac
    15481 agtaaatttg aaacaatatg tttgggtgag taacgtgaac caaggtgtaa taagtcttta
    15541 aattcatcaa cacttaactc tactttattg ttatcatcac aagtttcaat gaattgttca
    15601 atcattctcg aatatttaca ggtgtaactc ttcaattctt taaagtgaaa attgtgcttt
    15661 tctacaaatt gatttaaagc agttacagta ttttcttgtg aacgactgat gttatgggtg
    15721 tagcccatcg tggtttcaaa attcgcatga ccaactctag tcataatatc ctttacagct
    15781 atgtgcattt cattactttg aagataacta atgtgcatat gtctgaaaga atgaggggtc
    15841 acatgcttga cccattcaac cctcttcaaa acttgacgaa atgagtgaga agttatcgga
    15901 gaaccatact cagtttgaaa tacactatca cactttttga aagcaggact aggattttgt
    15961 tccatatagg cttcaaattc ctgatttctt tttatagctc tctggattgc ttcactcgct
    16021 gctattggga gggctacctc tctatcagca ttgacggtct tagtcgtatc aaaataaaat
    16081 tcatcaactt ttaaatcatg atattggaga gccttatcaa tatgtaaaat ccccttatca
    16141 aaatcaacat ctgatggtaa aaaagcagcc tctccaatcc gaatccctgt cagtaataat
    16201 acaatagcaa ggtcataata gctagcattt ctacactgcc ctaaaacatc aaaaaaggct
    16261 tgcaattcat gaatttcaag aaatttagca tcaagccttt ttcttgcttc tctctttttc
    16321 tccagaggca catctatttt aacagcggtc attggagagt acttaatgac attgtatagc
    16381 acaccgtgat taaatatctt gttacacgta ctttttatat gtgtcattgt tgaaggtgaa
    16441 gcgtcgtatt tatccagata tttattaaga caatttttca tcagtagtgg tgtaattcga
    16501 tcgagtaaaa attcatcacc gataatttta ccaagccgtt ctatcaccaa ctcttccctt
    16561 tttattgtct ggggcttgac agatacgcac caagtttgaa accaactctc ttttaactct
    16621 ccaaaagttg taatcatttc aggattgtac tgactttcaa gggaagaggt cagtttttct
    16681 attttatcca ttacctctct ttcagcttgc tttcgtgctc tactagtatt tctagtatag
    16741 ctgacagtta ctgttctcca cttatcagta agtggatctt tacatttttc aaccacttga
    16801 tacaagggtt gtccttttga atttgtttta gttacataat acataattta attcctcgaa
    16861 aagaaataaa tcattgttgt atagaataaa taactactct atattatacc atgacttcct
    16921 tattttgtcc gcttttgttt ccatctcaaa aagcattcga atccctcaag atttataaac
    16981 accagcttat gtgtaggatt gatgacgtat aaagaaaatc tcttattttc tctcatttct
    17041 ttgatccatc tgttaagagt gtagagattc aaaccttccc atcgtttcag tatgcttttc
    17101 ttatccgccc actcagctac cgaattttca acagatacgt attttatctc catattatca
    17161 tcctttcgaa taatttcttc tccctccatg gcatgactga tggggtcatc ataagaatct
    17221 cacttactgc tcttttacga cggcagcctg aacgttcaga agtatcattg tatatcattt
    17281 gcatcatggc agatagagta tcgctctatt ttattggtga ttgtccccgc tcctatcttg
    17341 gcgaatcaag caaaactgct ccacaaatga ggaaagtacc attttaggct attcagttgt
    17401 caaagggcaa ataaaaaatc tcactcattt tcaaactcta tgaaattgag gagattattt
    17461 tctaaagcga attttatcag gaaaatcaca gttaatccca ataaatagtc tgtactgacg
    17521 tcatagaaat ctgagagttt aaccaataca tcagccgtca acgcatgctc accccgttca
    17581 attttggcat aagctgaatt tgtaaacgaa agtattgtag ctatttgctt ttggggcaga
    17641 tcatgatcct ccctcaaatc tctcaaacgt ctgtacatct agctttctcc taagaaaaag
    17701 tatagaccat atattgtaac tatttaggat attgtccaaa tcggacaaca ggaattttac
    17761 catcctttat atagactttt atttttatgt atcaagtttt ttaaatcaaa accaccagtg
    17821 tgaactggtg gtttgttctg cggctataag ccgcttctac cggccagggc caaaggccca
    17881 ccgaaatagc ttcctcgcgc accactttcc cgagcaggtg ctaaagcacc ttagttactt
    17941 cctcttattt atttcgccag taaacggatc tactgactcg aataacgtga gctggtctgc
    18001 tactctgtct tcttgtaatt gattctgaat atattcagct atcactttct gattacggcc
    18061 taccgtatct acataatagc ctctacacca aaacttgcga ttgccatatt tgtattttaa
    18121 attcgcatgc ttatcaaaaa tcatcaaact gctcttgccc tttaaatagc ccataaagga
    18181 caaaacacta agtttcggag gaatactgat aagcatgtga atatggtctg aacaagcatt
    18241 cgcttcatgg attattacac ccttacgctc acataagtca cgtatgattc ttccgatact
    18301 agctttgtat ctgccataaa tgatttgacg acgatatttg ggtgcaaaaa caatatgata
    18361 tttacaattc catgtggtat gtgataaact ttgattatcc tctctcatga ggtacctcct
    18421 gtatgatatg ttgtagtggc ggagaaacca cttctatctt atcattttag gaggttcttt
    18481 ttgttaccac gctaaaagct ctatggaacc actagcatag ctagtggttt tcgggagaca
    18541 acaaaaaagt tggatgaccc aacttttatc tttctatcag tatcaatttt atctttggta
    18601 taataaaaga tacagatata aggacaagta atgatgttaa caataagaaa actaattcca
    18661 aagttgttga atttttaaaa taaaagtttc tcaaaatagt taattgataa gttaagggat
    18721 ttaactgacc aatccatctc acaatactag gagcagaatc tattaagtag aaaacaggag
    18781 ctgtaaaacc aagcggtgtt agtacaaaac gtattacaat atcacgtctt ctgtaatcat
    18841 tgataaacat tgtaagtaaa attgcaaggg agtcccaaaa taataaaaca acaatagata
    18901 acaaaactgt ataaaaaaat ctatccattg cgatatttat ctcaaacgct aacgtaatta
    18961 tatatataat a
//
LOCUS       DAVLXH010000040        18955 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00028199
            SAMN33607166-rid17955573.denovo.040, whole genome shotgun sequence.
ACCESSION   DAVLXH010000040 DAVLXH010000000
VERSION     DAVLXH010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607166
            Sequence Read Archive: SRR23725544
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18955)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18955)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721421.1
            Genome Coverage       :: 115x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:42:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,210
            CDSs (total)                      :: 2,161
            Genes (coding)                    :: 2,023
            CDSs (with protein)               :: 2,023
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 73 of 138
            Pseudo Genes (incomplete)         :: 60 of 138
            Pseudo Genes (internal stop)      :: 40 of 138
            Pseudo Genes (multiple problems)  :: 31 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18955
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607166-rid17955573.denovo.040"
                     /strain="AUSMDU00028199"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1349"
     gene            8..6031
                     /locus_tag="VYO11_001532"
     CDS             8..6031
                     /locus_tag="VYO11_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HEV1596075.1"
                     /translation="MEKYFGEKQERFSFRKLSVGLVSATISSLFFMSVLASSSVDAQE
                     TAGVHYKYVADSELSSEEKKQLVYDIPTYVENDDETYYLVYKLNSQNQLAELPNTGSK
                     NERQALVAGASLAALGILIFAVSKKKVKNKTVLHLVLVAGIGNGVLVSVHALENHLLL
                     NYNTDYELTSGEKLPLPKEISGYTYIGYIKEGKTTSDFEVSNQEKSAATPTKQQKVDY
                     NVTPNFVDHPSTVQAIQEQTPVSSTKPTEVQVVEKPFSTELINPRKEEKQSSDSQEQL
                     AEHKNLETKKEEKISPKEKTGVNTLNPQDEVLSGQLNKPELLYREETIETKIDFQEEI
                     QENPDLAEGTVRVKQEGKLGKKVEIVRIFSVNKEEVSREIVSTSTTAPSPRIVEKGTK
                     KTQVIKEQPETGVEHKDVQSGAIVEPAIQPELPEAVVSDKGEPEVQPELPEAVVTDKG
                     EPAVQPELPEAVVSDKGEPEQVAPLPEYKGNIEQVKPETPVEKTKEQGPEKTEEVPVK
                     PTEETPVNPNEGTTEGTSIQGAENPVQPAEESTTNSEKVSPDTSSENTGEVSNKPSDS
                     TTSVGESNKPEHNDSKNENSEKTVEEVPVNPNEGTVEGTSNQETEKPVQPAEETQTNS
                     GKIANENTGEVSNKPSDSKPPVEESNQPEKNGTATKPENSGNTTSENGQTEPEPSNGN
                     STEDVSTKSNTSNSNGNEEIKQENELDPDKKVEDPEKTLELRNVSDLELYSLSNGTYK
                     QHISLEQVPSNPNSYFVKVKSSSFKDVYLPVASISEERKNDKILYKITAKVEKLQQEI
                     ESRYKDNFTFYLAKKGTEETTNFTSFSNLVKAINQNLSGTYHLGASLNANEVELSTDD
                     KSYIKGTFTGQLIGEKDGKHYAIYNLKKPLFENLSGATVEKLSLKNVAISGKNDIGSL
                     ANEATNGTKIKQVHVDGVLAGERGVGGLLAKADQSSIAESSFKGRIVNTYETTDSYNI
                     GGLVGHLTGKNASIAKSKATVTISSNTNRSDQTVGGLAGLVDRDAQIQDSYAEGDINN
                     VKHFGRVAGVAGNLWDRTSGDVRHAGSLTNVLSDVNVTNGNAITGYHYTGMKVANTFS
                     SKANRVFNVTLEKNEVVSKESFEERGTMLDASQIASKKAEINLITPPIVEPLSTSGKK
                     DSDFSKIAHYQANRALVYKNIEKLLPFYNKATIVKYGNLVKENSILYQKELLSAVMMK
                     DDQVITDIISNKQTANKLLLHYKDHSSEKFDLRYQADFANLAEYSIGDSGLLYTPNQF
                     LYHQDSIINQVLPELNRVNYQSDAVRNTLGISPEVKLTELYLEEQFTKTKEHLAENLK
                     KLLSSDAGLVTDNEVMTGYIIDKIKRNKEALLLGMSYLERWYNFSYGQVNVKDLVMYH
                     PDFFGKGNTSPLDTLIELGKSGFNNLLAKNNVDTYAISLASHHGTTDLFSTLENYRKV
                     FLPDKTNNDWFKSQTKAYIVEEKSNIEEVKTKQGLVGTKYSIGVYDRITSATWKYRNM
                     VLPLLTLPERSVFVISTISSLGFGAYDRYRNKEHQANGDLNSFVEKSAHETAERQRDH
                     YDYWYRILDEKGREKLYRNILLYDAYKFGTNHTEGKATEVADFDSPNPAMKHFFGPVG
                     NKVGHNGHGAYATGDAVYYMGYRMLDKDGAITYTHEMTHNSDQDIYLGGYGRRSGLGP
                     EFFAKGLLQAPDQPSDATITINSILKHSKSDSKEGERLQVLDPTTRFKDATDLQKYVH
                     NMFDVVYMLEYLEGKSIVKKLNVYQKIEALRKIENQYLTDPADGNDVYATNVVKNLTE
                     DEAKKLTSFDSLIDNNILSAREYKAGTYERNGYFTIKLFAPIFSALSGEKGTPGDLMG
                     RRIAFELLAAKGFKDGMVPYISNQYEEDAKQQGQTINLYGKERGLVTDELVLKKVFDG
                     KYKTWAEFKTAMYQERVDQFGNLKQVTFKDPTKPWPRYGTKTINNVDELQKLMDEAVL
                     QDAKERNYYYWNNYNPETDSAVHKLKRAIFKAYLDQTNDFRRSIFENKK"
     gene            6075..11399
                     /locus_tag="VYO11_001533"
     CDS             6075..11399
                     /locus_tag="VYO11_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000054780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HEV1596076.1"
                     /translation="MSLLKKDKFSIRKIKGIVGSVFLGSLLFAPSVVGTSTYHYLDYS
                     TLTQTERVQLKQGRPDESKESYALVYEKDALPNTGSSQSIMTALGLLAIGSLIVIITK
                     DKKRKKIATFLIVGATGLVTLSTASALNLNANIHESGRDGVLQISGYRYVDYLELDDR
                     TVSPVEQPKVVTDKGEPEVQPALPEAVVTGKGKTEVQPTLPEAVVTEKGEPEVQPVLP
                     EAVVAEKGEPEVQPALPEAVVTEKGEPEVHEKPDYTQPIGANLVEPEVHEKLAYTEPV
                     GTTGVDENRNLIEPPVNDIPEYTEPISTVSEVASEREELPSLHTDIRTETIPKTTIEE
                     SDPSKFIGDNSVKQVGEDGERQIVTSYEELHGKKISESVETVTILKEMKPEIIVKGTK
                     ERPKEKTAPVLTLTKVTEDAMNRSANLNYELDNKDNAEISSIVAEIKDGDTVVKRVDL
                     SKEKLTDAVQNLDLFKDYKIATTMIYDRGQGSETSKLDERPLRLELKKVEIKNIASTN
                     LVKVNDDGTETPSDFMNEKPSEEDVKKMYLKITSRDNKVTRLTVDSIEEVTEEGQKLY
                     KITAEAQDLIQHTDPTKVRNKYVYYIEKPHPKEDNVYYNFKDLVDAMNTDKNGTFKLG
                     ADLNATGVPTPKKWYVDGDFRGTLKSVEGKHYTIHNTERPLFQNIIGGTVTKVNLGNV
                     NINMPWADRIAPIADTIKGGAKIEDVKVTGNVLGRNWVSGFIDKIDNQGTLRNVAFIG
                     NVTSVGDGGQFLTGIVGENWKGLVERAYVDANLIGKKAKAAGIAYWTQNSGDNHKVGV
                     EGAVKKGIVKGTIQVESPVEVGGAVGRLSHHGYIGEVVSMMKVKKGEIFYGSSDMNDD
                     PYWVANNVRGNYVVNGVSEGTISYARAKEHHRIKPISQSEADTKIMMLGITAQDFAIN
                     EPVVNRLNRLTRKEDEYKSTQDYKVDRDLAYRNIEKLQPFYNKEWIVNQGNKLAEDSN
                     LAKKEVLSVTGMKDGQFVTDLSDIDKIMVHYADGTKEEMDVTKNADSKVKQVREYTIA
                     GQNVVYTPNMVEKDRNQLIQDIKDKLASVQLISPEVRALMDARKKPEENTDERKNGYI
                     KDLYLEESFAETKANLDKLVKSLVENADHQLNSDEAAMKALVKKVDENKAKIMMALTY
                     LNRYYDIKYGDMTIKNLMMFKPDFYGKSVDLLDFLIRIGSSERNIKGDRTLDAYRDMI
                     GGTIGKSELHGFLDYNMRLFTNDTDLNDWFIHAAKNVYVSEPQTTNPDFVNKRHRAFD
                     GLNNGVHNRMILPLLTLKNAHMFLISTYNTMAYSSFEKYGKYTEEARNEFKKEIDKVA
                     HAQQTYLDFWSRLALPSVRDQLLKSENRVPTPVWDNQNYSGIKGINRMGYDEKKVPIA
                     PIRELYGPTWKFHNTNWNMGAMASIFPNPNNNDQVYFMGTNMISPFGISAFTHETTHV
                     NDRMLYFGGHRHRQGTDVEAYAQGMLQTPSSIGHQGEYGALGLNMAYHRENDGDQWYN
                     YDPDKLQTREDIDRYMKNYNEALMMLDHVEADAVLPQLNGDNSKWFKKIDREIRRNLG
                     DGLNNLVAPHQWDNVRDLNQEESSKKLSSINDLIDNNFMTKHGNPGNGRYRPEDFRPN
                     SAYVNVNMMAGIYGGNTSQGAPGSLSFKHNAFRMWGYYGYDKGFTSYVSSKYQGEADK
                     QNQGRLGDDFIIKKVSNNQFSNLEDWKKYWYHDVKSRAEKGFTEITIDGQTIHNYNEL
                     KDLFDKAVTEDLKKAGNYSNTENLKSKVFKALLKNTDGFFNPLFKKDI"
     gene            11566..12912
                     /locus_tag="VYO11_001534"
     CDS             11566..12912
                     /locus_tag="VYO11_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1380-like element ISSpn5 family transposase"
                     /protein_id="HEV1596077.1"
                     /translation="MNSLPNHHFQNKSFYQLSFDGGHLTQYGGLIFFQELFSQLKLKE
                     RISKYLVTNDQRRYCRYSDSDILVQFLFQLLTGYGTDYACKELSADAYFPKLLEGGQL
                     ASQPTLSRFLSRTDEETVHSLRCLNLELVEFFLQFHQLNQLIVDIDSTHFTTYGKQEG
                     VAYNAHYRAHGYHPLYAFEGKTGYCFNAQLRPGNRYCSEEADSFITPVLERFNQLLFR
                     MDSGFATPKLYDLIEKTGQYYLIKLKKNTVLSRLGDLSLPCPQDEDLTILPHSAYSET
                     LYQAGSWSHKRRVCQFSERKEGNLFYDVISLVTNMTSGTSQDQFQLYRGRGQAENFIK
                     EMKEGFFGDKTDSSTLIKNEVRMMMSCIAYNLYLFFKHLAGGDFQTLTIKRFRHLFLH
                     VVGKCVRTGRKQLLNLSSLYAYSELFSALYSRIRKVNLNLPVPYEPPRRKASLMMH"
     gene            complement(13075..14244)
                     /locus_tag="VYO11_001535"
     CDS             complement(13075..14244)
                     /locus_tag="VYO11_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000949617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEV1596078.1"
                     /translation="MLSLDQIHLLLNTPEDEFHDFKQKWHHSKTELVRDILNFVNTSH
                     HEDCYIIFGIDNITLDIIGVNNDDNRRNEEDLTDLLHKLFISTNNQIKISIQTETIDN
                     KEIDILIIHDTDKVPVFLTKDYKPKKDTALPKGLIYARNGSINTPKDSSAPFELINEL
                     FQKFNHTDLNIKEQYFHVLKDYKNWFFIENEDGRFFIYNPNPDFYIKLNDDDANRFKT
                     MSYSLNQYQTNIDWQLVQLRYRHLTIDECMAMYLDQGNCLVPSPEVESFKIDYQETIY
                     YHCLYKNTLKYQLLKVFSSIPGLEKYPLTRFKNSIVIYDTKLELKKTHNLINSKFSSK
                     DIVNQLEVTEKDFDFYYKKARHKNPDYSIQENQVNLTELNLVRLLKPQIIHTSLN"
     gene            14606..14962
                     /locus_tag="VYO11_001536"
     CDS             14606..14962
                     /locus_tag="VYO11_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000817622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1596079.1"
                     /translation="MKRDVRDIRKQFRLTEAEEKQILALMRERGETNFSDFLRKSLLS
                     SDLQKQMETWFALWQSQKLEQISRDVHEVLILAQSERQVTQEHVSILLTCVQELIQEV
                     ANTIPLSKEFREKYMR"
     gene            14967..15332
                     /locus_tag="VYO11_001537"
     CDS             14967..15332
                     /locus_tag="VYO11_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000263054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HEV1596080.1"
                     /translation="MEHRYRTNLKKVFLSDSELNQLNINIDQSGCKSFSEYARRTLLD
                     PGMNFITIDTNGYQDLVFELKRIGNNINQIARSVNQSQLISGEELQELKKGIGELIKE
                     VDKEFNLQAQKLKEFHGHH"
     gene            15319..17142
                     /locus_tag="VYO11_001538"
     CDS             15319..17142
                     /locus_tag="VYO11_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002917262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HEV1596081.1"
                     /translation="MVITKHFAIHGKSYRRKLIKYILNPEKTNNLALVSDYGMKNFLD
                     FPSYEEMVQMYHENFISNDTLYDFRHDRMEENQRKIHAHHIIQSFSPEDHLTPEQINR
                     IGYETVKELTGGKFRFIVATHVDKDHLHNHIIINSVDSNSDKKLKWDYKVERNLRMIS
                     DRFSKIAGAKIIENRYSHQRYEVYRKTNHKYELKQRLYFLMEHSRDFEDFKKNAPLLH
                     VEMDFRHKHATFFITDSTMKQVVRGKQLNRKQPYTEEFFKNYFAKREIESLMEFLLLK
                     VENMDDLLQKAKLFGLTINPKQKHVSFQFAGVEVKETELDQKNLYDVEFFQDYFKNRK
                     DWQAPETEDFVQLYQEEKLSKEKELPSDEKFWESYQEFKSNRDAVHEFEVELSLNQIE
                     KVVDDGIYVKVKFGIRQEGLIFVPNMQLDMEEDKVKVFIRETSSYYVYHKDAAEKNCY
                     MKGRTLIRQFSYENQTIPLRRKATVDMIKEKIAEVDALIELEVENQSYVTIKDELVHE
                     LAASELRINELQERMSTLNQVAEYLLASVESKQEMKLNLSKLNITENISANIVEKKLK
                     SLGNQLELERGRYEKMVVRLDKFINRLNTGLSKGDGIDFQK"
     gene            17256..18122
                     /locus_tag="VYO11_001539"
     CDS             17256..18122
                     /locus_tag="VYO11_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000537001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1596082.1"
                     /translation="MGTLLATRLKNRRKELKMSQRELAEGICKQGQISRLESGEFTPG
                     ADFLHALAKKLKVSMDYFFDEQVVEEVNELSEFKKLAQTFITNRNYESLKYIYELENV
                     KAHRLSLADKFYMEWIKSLIDFYFYGQKEEAITRLENMLPQLNVSDLNYLQVSNTLFN
                     FYYDIEDLERFNEIRDKLEHQVNQLNLNTIEELELSIKFNYNVCRYLWLQKNIEEAIT
                     KITATIKQCKEYRTTYLLADLYLLMGSVSENFSSKSSVKEYFETAHFLYKLEENMSMA
                     LKVEHYFADITE"
     gene            18713..>18955
                     /locus_tag="VYO11_001540"
     CDS             18713..>18955
                     /locus_tag="VYO11_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000098314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1596083.1"
                     /translation="MSSQMKAFLNELQGNMEVVGEFFDNPEKVIRKFGIVGREKEALL
                     IRDLNDMDDYALSIQNSVASPSGAHSSTCHFVRQDLQ"
BASE COUNT         6695 a         3056 c         3790 g         5414 t
ORIGIN      
        1 aggaataatg gaaaagtatt ttggtgaaaa acaagagcgt ttttcattta gaaaattatc
       61 agtaggactt gtatctgcaa cgatttcaag tttatttttt atgtctgtat tagctagttc
      121 atctgtggat gctcaagaaa ctgcgggagt tcactataaa tatgtggcag attcagagct
      181 atcatcagaa gaaaagaagc agcttgtcta tgatattccg acatacgtgg agaatgatga
      241 tgaaacttat tatcttgttt ataagttaaa ttctcaaaat caactggcgg aattaccaaa
      301 tactggaagc aagaatgaga ggcaagccct agttgctggt gctagcttag ctgctctggg
      361 aattttaatt tttgctgttt ccaagaaaaa ggttaagaat aaaacggtat tacatttagt
      421 attggttgcg ggaataggaa atggtgtctt agtttcagtc catgctttag aaaatcatct
      481 tttgctaaat tacaatacgg actatgaatt gacctctgga gaaaaattac ctcttcctaa
      541 agagatttca ggttacactt atattggata tatcaaagag ggaaaaacga cttctgattt
      601 tgaagtaagt aatcaagaaa aatcagcagc cactcctaca aaacaacaaa aggtggatta
      661 taatgttaca ccaaattttg tagaccatcc atcaacagta caagctattc aggaacaaac
      721 acctgtttct tcaactaagc cgacagaagt tcaagtagtt gaaaaacctt tctctactga
      781 attaatcaat ccaagaaaag aagagaaaca atcttcagat tctcaagaac aattagccga
      841 acataagaat ctagaaacga agaaagagga gaagatttct ccaaaagaaa agactggggt
      901 aaatacatta aatccacagg atgaagtttt atcaggtcaa ttgaacaaac ctgaactctt
      961 atatcgtgag gaaactatag agacaaaaat agattttcaa gaagaaattc aagaaaatcc
     1021 tgatttagct gaaggaactg taagagtaaa acaagaaggt aaattaggta agaaagttga
     1081 aatcgtcaga atattctctg taaacaagga agaagtttcg cgagaaattg tttcaacttc
     1141 aacgactgcg cctagtccaa gaatagtcga aaaaggtact aaaaaaactc aagttataaa
     1201 ggaacaacct gagactggtg tagaacataa ggacgtacag tctggagcta ttgttgaacc
     1261 cgcaattcag cctgagttgc ccgaagctgt agtaagtgac aaaggcgaac cagaagttca
     1321 acctgaatta cccgaagcag ttgtgaccga caaaggtgag cccgctgtcc aacctgaatt
     1381 acccgaagca gttgtaagtg ataaaggtga accagagcag gtagcaccat tgccagaata
     1441 taaggggaat attgagcaag taaaacctga aactccggtt gagaagacca aagaacaggg
     1501 tccagaaaaa acggaagaag ttccagtaaa accaacagaa gaaacaccag taaatccaaa
     1561 tgaaggtact acagaaggaa cctcaattca aggagcagaa aatccagttc aacctgcaga
     1621 agaatcaaca acgaattcag agaaagtatc accagataca tctagcgaaa atactgggga
     1681 agtatccaat aaacctagtg attcgacaac ctcagttgga gaatcaaata aaccagaaca
     1741 taatgactct aaaaatgaaa attcagaaaa aactgtagaa gaagttccgg taaatccaaa
     1801 tgaaggcaca gtagaaggga cctcaaatca agaaacagaa aaaccagttc aacctgcaga
     1861 agaaacacaa acaaactctg ggaaaatagc taacgaaaat actggagaag tatccaataa
     1921 acctagtgat tcaaaaccac cagttgaaga atcaaatcaa ccagaaaaaa acggaactgc
     1981 aacaaaacca gaaaattcag gtaatacaac atcagagaat ggacaaacag aaccagaacc
     2041 atcaaacgga aattcaactg aggatgtttc aaccaaatca aacacatcca attcaaatgg
     2101 aaacgaagaa attaaacaag aaaatgaact agaccccgat aaaaaggtag aagatccaga
     2161 gaaaacactt gaattaagaa atgtttccga cctagagtta tacagtttgt caaatggtac
     2221 ttataaacaa cacatttcgt tagagcaagt tccaagcaat ccaaatagct actttgttaa
     2281 agtgaaatct tcttcattca aagatgtata cctaccagta gcatcaatat cagaggaaag
     2341 aaaaaatgat aaaatccttt ataaaatcac agcaaaagta gagaagcttc agcaggagat
     2401 agaaagcaga tataaagata attttacctt ctatctagct aagaagggaa cagaagaaac
     2461 aacaaacttt acttccttta gtaatctggt caaagctata aaccaaaatc tctctggaac
     2521 ctatcattta ggagctagcc tgaatgctaa cgaagtggag cttagtactg atgataaatc
     2581 ctatatcaag ggaaccttta ctggtcagtt gattggtgaa aaagatggta agcattatgc
     2641 tatttacaac ttgaaaaagc ctctttttga aaacttgagt ggtgctacag tagaaaaact
     2701 gagtctaaaa aatgttgcta tttcagggaa aaatgatatt ggttcactgg caaatgaagc
     2761 tacgaatggc acaaagatta aacaagttca tgttgatggt gttcttgctg gagaacgtgg
     2821 tgtcggtggt ttgttggcta aggcagacca atcaagcatc gcagagagca gtttcaaggg
     2881 aagaattgtc aatacctatg aaacgactga ttcctacaat attggcggtc tggtcggtca
     2941 tttaacagga aaaaatgcgt ctattgctaa atccaaagcg acagtaacca tttcgtcaaa
     3001 caccaatagg tcagatcaga ctgtcggtgg tcttgcaggt ctagtagacc gagatgcaca
     3061 gatccaagat agctatgctg aaggtgatat caacaatgtc aagcactttg gtagagtcgc
     3121 tggagtggca ggcaatttgt gggatcgaac ttctggtgat gttaggcatg ctggaagttt
     3181 gaccaatgtt ctcagcgatg ttaatgtaac aaacggaaat gccatcactg gataccacta
     3241 tacaggaatg aaggtagcta atacatttag tagtaaggct aatagagttt tcaatgtcac
     3301 tttagagaag aatgaggtcg tcagcaaaga atccttcgag gaaagaggaa caatgctaga
     3361 tgcttctcaa attgcaagca aaaaagcaga aatcaatctt atcactccac caatagtgga
     3421 acccctctca acaagcggta agaaagacag tgatttttct aagatagccc attatcaagc
     3481 caaccgtgct ttggtttata agaacattga aaaattgtta cctttctata acaaggcgac
     3541 catcgtgaaa tacggaaacc tggttaagga gaacagtatc ttatatcaaa aagaactctt
     3601 gtctgcagtt atgatgaagg atgaccaagt aatcacagat attatttcca acaaacagac
     3661 tgcaaacaaa ctcttgcttc actacaagga ccattcatct gaaaagtttg atctcaggta
     3721 ccaggctgat tttgccaatt tggcagaata tagcattgga gatagtgggc ttctctatac
     3781 gccaaatcaa ttcttgtatc atcaagattc tattattaac caagtgctgc ctgaattgaa
     3841 tcgagtaaat tatcaatcag atgctgttag aaatacactt ggaatttcac cagaagtgaa
     3901 gctaacggag ttatatcttg aagaacaatt taccaaaacg aaagagcatc tagcagagaa
     3961 cttgaaaaaa cttttatcat ctgatgcagg tttagtaaca gacaatgaag ttatgacagg
     4021 atatataata gataaaatta aacggaataa ggaagcctta cttcttggaa tgagttattt
     4081 agaacgttgg tataacttta gctatggtca agtgaatgtc aaagacctag ttatgtatca
     4141 tccggacttc tttggtaaag gaaatacttc accattagat actctgattg agttaggtaa
     4201 atctggcttt aacaatcttc ttgctaaaaa caatgtcgat acttatgcta tcagccttgc
     4261 cagccatcat ggaacgacag atttgtttag cacgttggaa aattaccgaa aagtctttct
     4321 accagataaa accaataatg actggtttaa atcacagact aaggcttaca ttgtcgaaga
     4381 aaaatccaat atcgaagagg tgaaaacgaa gcaaggacta gttggcacta agtattctat
     4441 tggtgtctat gaccgtatca ctagtgccac atggaaatac cgtaatatgg tactacctct
     4501 acttaccttg ccagaaagat ccgtatttgt catttcaacc atatctagtc taggttttgg
     4561 tgcttatgat cgctatcgta ataaagaaca tcaagcaaat ggtgatctta atagctttgt
     4621 tgaaaagagt gctcacgaaa cagcagagcg tcaacgagat cactatgatt attggtatcg
     4681 tattctagat gaaaaagggc gtgaaaagct ttatcgaaat atcttgcttt atgatgccta
     4741 taaatttgga actaatcata ctgaaggaaa ggctacagaa gtagcagatt ttgatagtcc
     4801 aaatcctgca atgaaacatt tctttggacc tgttggaaat aaggttggac ataatggaca
     4861 tggtgcttat gctacagggg atgcagtata ttatatgggg tatcgcatgc tagataagga
     4921 tggagctatt acgtatactc atgagatgac gcataattca gatcaagata tttatcttgg
     4981 tggttatgga agaagaagtg gacttggacc tgagttcttt gctaaaggct tactacaagc
     5041 accagaccaa ccaagtgatg caacgattac tatcaattct atattgaaac attcaaaatc
     5101 tgatagtaaa gaaggagaac gattacaagt acttgatcca actacgagat ttaaagacgc
     5161 aacagatctt caaaaatacg tccacaatat gtttgatgtt gtttatatgt tggaatatct
     5221 cgaaggtaaa tctattgtta agaaattaaa tgtatatcag aaaatagaag ctctcagaaa
     5281 aatcgagaac caatatctaa cagatcctgc tgatggaaat gatgtttatg ctactaatgt
     5341 tgtgaaaaat ttgactgaag atgaagctaa aaaattgacg agctttgata gtttgattga
     5401 caataacatt ctttcggctc gtgagtataa ggctggcact tatgagagaa atggctactt
     5461 tactataaaa ctctttgcac caatcttttc agcattgagc ggtgagaaag gaactccagg
     5521 tgaccttatg ggacgaagga tagcttttga acttctagct gctaaaggat ttaaagatgg
     5581 tatggtacca tatatttcca accaatacga agaagatgct aaacaacaag ggcaaactat
     5641 caatctttat ggtaaagaac ggggcttggt gaccgatgag cttgttttga aaaaggtatt
     5701 tgatggtaag tataaaactt gggcagaatt taagacagct atgtaccaag aacgggtgga
     5761 tcagtttgga aacttgaagc aggtgacctt taaagatccg acaaaaccat ggccaagata
     5821 tggcacaaag actatcaata atgtggatga attgcagaaa ctaatggatg aagctgtttt
     5881 gcaggatgca aaagaacgta attattatta ttggaataac tataatccag aaacggacag
     5941 tgccgtccat aagttgaaga gagcaatctt taaagcctat cttgaccaaa caaatgattt
     6001 tagaagatca atttttgaga ataaaaaata gtgtttacta ttaggaaata aaaagtgaat
     6061 gtggaggatt agaattgtca ttattaaaaa aagataaatt ttccattcgg aaaataaagg
     6121 gtattgttgg ttcggtattc ttggggagtc ttttatttgc accgtcagtt gttggtacat
     6181 cgacttatca ttacttagat tatagtactt tgacacaaac tgaacgtgtt caactcaaac
     6241 aaggtagacc tgatgaatca aaagagtcat atgctttggt ttatgaaaaa gacgcattac
     6301 caaacacagg aagttctcaa tctattatga ctgcattggg tttgttagct atcgggagtc
     6361 ttattgtgat tatcacaaaa gataaaaaga ggaaaaaaat cgctacattt ttgattgtag
     6421 gggcgacagg tttagttaca ctatcaactg cttcagcact taatttgaat gctaacatcc
     6481 atgagtctgg acgtgatggt gtgttgcaaa tttctggtta cagatatgtt gattacttgg
     6541 agcttgatga tagaactgtt tctccagttg agcaacccaa agttgtgacc gacaaaggcg
     6601 aaccagaagt tcagccagcg ttaccagaag ctgttgtaac tggaaaaggg aaaactgaag
     6661 tacaaccgac attaccagaa gctgttgtga ctgaaaaagg ggaaccggaa gtacaaccag
     6721 tgttaccaga agctgttgtg gctgaaaaag gggaaccaga agtacaacca gccttacccg
     6781 aagcagttgt aactgaaaaa ggcgaaccag aagttcatga gaagcctgac tatacgcaac
     6841 caataggtgc aaaccttgtt gagcctgaag ttcatgagaa actagcatac actgaacctg
     6901 taggtacaac aggagtagat gaaaatagaa acttgattga gccacctgtt aacgatattc
     6961 cagagtatac tgaaccaata tctacagttt cagaagttgc atcagaaaga gaagagttgc
     7021 cttctttaca taccgatatt cgtacagaga ctattcctaa aaccactata gaagaatctg
     7081 atcctagcaa atttataggc gataattctg ttaaacaagt tggtgaggat ggcgaacgtc
     7141 aaattgttac tagctatgaa gagttacatg gcaaaaaaat cagcgagtca gttgaaacag
     7201 taacaatttt gaaagaaatg aagcctgaaa ttattgtaaa aggtacaaaa gaaagaccaa
     7261 aagaaaaaac ggctcctgtt ttaaccttga ccaaagtaac agaagatgct atgaatcgtt
     7321 ctgccaactt aaattatgag cttgataata aagataatgc tgaaatatca agtattgtag
     7381 ctgaaattaa agatggtgat acagtagtta aaagggttga tttatctaaa gaaaaattaa
     7441 ctgacgctgt acaaaatttg gatttgttta aagattataa gattgcaaca acaatgattt
     7501 atgatcgtgg tcaaggttct gaaacgtcta aactggatga aagacctctg cgtttggagt
     7561 tgaaaaaggt cgaaattaaa aatatcgcat ctactaattt agtgaaggta aatgatgatg
     7621 gtactgaaac acctagtgat tttatgaatg aaaaaccttc agaagaagat gttaaaaaaa
     7681 tgtacttaaa aatcactagt cgcgataata aggtaactcg tttaactgta gactctattg
     7741 aagaagtgac tgaagaaggt caaaaacttt acaaaataac tgctgaagca caagatttga
     7801 ttcaacacac agacccaacg aaggttcgta ataagtatgt ttattatata gaaaaacccc
     7861 atcctaaaga agataatgtc tactataact ttaaagattt agtagatgct atgaatactg
     7921 ataaaaatgg tacatttaaa cttggtgcag atttgaatgc cactggtgtt ccaacaccta
     7981 agaaatggta tgttgacggc gactttagag gtacattgaa gagtgtagag gggaaacatt
     8041 atactatcca caacacggag cgtccgttat tccagaatat tattggtggt acagtaacca
     8101 aagtaaatct gggaaatgta aatatcaata tgccatgggc agaccgcatc gcaccgattg
     8161 ctgacactat taaaggtggc gctaaaattg aagatgtcaa agtgactggt aacgtattag
     8221 gtagaaactg ggtatctgga tttattgata agattgacaa ccaaggtaca ctcagaaatg
     8281 tagcctttat cggaaatgtg acatctgtag gtgatggtgg tcaattcttg accggtatcg
     8341 ttggtgagaa ctggaaagga ctagtcgaac gtgcgtatgt tgacgcaaat cttattggca
     8401 agaaagccaa ggctgctggt attgcttatt ggacacaaaa cagtggtgac aatcataaag
     8461 ttggtgtcga aggtgcagtc aagaaaggaa ttgtgaaggg taccattcag gtagaaagtc
     8521 ctgttgaagt cggcggtgct gttggacgtt tgagtcatca tggttatatc ggggaagtcg
     8581 tatctatgat gaaagttaag aagggtgaaa ttttttatgg ttctagtgat atgaatgatg
     8641 acccatattg ggtggcgaat aatgtacgag gaaattatgt agttaatggt gtgagtgaag
     8701 gtacgatatc ttatgctcgt gctaaagaac accatcgtat caaaccaatt tcacagtcag
     8761 aagcagatac taaaattatg atgttaggta ttacagcaca agattttgct atcaacgaac
     8821 ctgtggtcaa tcgcttaaac cgtttaacca gaaaagaaga tgaatataag tcaacccaag
     8881 actataaagt agatcgagat ctggcttatc gtaatattga gaaacttcaa ccattttata
     8941 acaaagaatg gattgtcaac caaggtaaca aacttgcaga agattcaaac ttagctaaga
     9001 aagaagtcct ttctgttacg ggtatgaagg atggacagtt tgtaactgac ttatcagata
     9061 ttgataagat tatggttcac tatgctgatg gtactaaaga agaaatggac gtcactaaga
     9121 atgctgattc taaagtgaaa caagttcgtg aatataccat cgctggacaa aacgttgttt
     9181 atacaccaaa tatggttgag aaagaccgta accaattgat tcaagatatc aaagataagt
     9241 tggcgtcagt tcaattgatt tctcctgaag tacgtgcttt gatggatgca cgtaagaaac
     9301 cagaagaaaa taccgatgaa cgtaagaatg gttatattaa agacctttac ttagaagaaa
     9361 gctttgctga aacgaaagct aatcttgata aattggttaa atccttagtt gaaaatgcag
     9421 atcatcaatt aaatagtgac gaagcggcta tgaaagcact tgttaagaag gtggatgaaa
     9481 ataaagctaa aatcatgatg gctctgactt atctcaatcg ttactatgat atcaagtatg
     9541 gggatatgac tatcaagaac ttgatgatgt ttaaacctga tttctatggt aaatcagttg
     9601 accttcttga tttcttgatt cgaattggat caagtgagag aaatatcaaa ggtgacagaa
     9661 ctttggatgc ttatcgtgat atgattggtg gaactattgg taagtctgaa ttacatggat
     9721 tcttagatta caatatgcgt ctcttcacta acgatactga tttaaatgat tggttcatcc
     9781 atgcagctaa gaatgtatat gtatcagaac ctcaaacaac gaacccagat tttgttaata
     9841 aacgacatcg tgcatttgat ggtttgaaca acggtgttca taatcgtatg attctacctc
     9901 tattaactct taagaatgca catatgttct tgatttcaac ttacaataca atggcttata
     9961 gttcttttga gaaatatggt aagtatacag aagaagctag aaatgaattc aaaaaagaaa
    10021 ttgataaggt tgcacatgct caacaaacat acttagactt ctggtcacgt ttagcattgc
    10081 caagcgtacg tgaccaatta ctcaagagtg agaatagggt accaactcct gtgtgggata
    10141 accaaaacta tagtggtatt aaaggaataa accgtatggg ttatgatgag aagaaagtac
    10201 caattgcgcc aattcgtgag ttatatggtc caacttggaa attccataat accaactgga
    10261 atatgggagc tatggcatct attttcccaa atcctaataa caatgaccaa gtttatttca
    10321 tgggaacaaa tatgattagt ccgtttggta tttcagcctt tactcatgaa actacacacg
    10381 ttaatgatag aatgctttac ttcggtggtc atagacaccg tcaaggtaca gacgtcgaag
    10441 cctatgctca aggtatgcta caaactccgt caagtattgg tcaccaaggt gaatatggtg
    10501 ctttaggttt gaacatggct tatcatcgtg aaaatgatgg tgaccaatgg tataactatg
    10561 accctgataa gcttcaaact cgtgaagata tcgatcgata tatgaaaaac tataatgaag
    10621 cactgatgat gctagatcat gtagaagcag acgccgtact tccacaattg aatggtgata
    10681 atagcaagtg gttcaagaaa attgatagag aaatacgcag aaatcttggg gatggtttga
    10741 ataacttagt agcaccgcac caatgggaca acgttcgtga cttaaatcaa gaagagagtt
    10801 ctaagaaatt atcaagtatt aacgatttga ttgataataa tttcatgacc aaacacggaa
    10861 atccaggtaa cggacgttat agaccagagg attttagacc aaactcagct tacgtaaatg
    10921 tcaatatgat ggcaggaatt tacggtggga atacgagtca aggtgctcct ggttcattat
    10981 cgttcaaaca taatgccttc cgtatgtggg gttattatgg atatgacaaa ggtttcacta
    11041 gttatgtatc tagcaagtat caaggtgaag ctgataaaca aaaccagggt agattaggtg
    11101 atgatttcat tatcaaaaaa gtttcaaaca accaattctc aaatcttgaa gattggaaga
    11161 aatattggta tcatgatgtg aaatccagag ctgaaaaagg attcacagag attacaattg
    11221 atggacaaac cattcacaac tataatgaac tgaaagactt attcgacaaa gctgtcacag
    11281 aagacctcaa gaaagctgga aactactcaa atactgagaa tttgaaatcc aaagtcttca
    11341 aagctcttct taaaaacaca gacggtttct ttaatccatt gttcaaaaaa gacatttaaa
    11401 ccccaattat gcacccctaa tctaaaaacc atccagaatc cttgccttag cttagatcct
    11461 ggatggtttc ttttttcacc caatgggtgt tttttactag acaaaaaaga gtttcccctt
    11521 tatggtataa gtgtagaaaa aaacacaaaa agaaaggaaa ctcatatgaa cagtttacca
    11581 aatcatcact tccaaaacaa gtctttttac caactatctt tcgatggagg tcatttaacc
    11641 cagtatggtg gtcttatctt ttttcaggaa cttttttccc agttgaaact aaaagagcgg
    11701 atttctaagt atttagtaac gaatgaccaa cgccgctact gtcgttattc ggattcagat
    11761 atccttgtcc agttcctctt tcaactgtta acaggctatg gaacggacta tgcttgtaaa
    11821 gaattgtcag ctgatgccta ctttccaaaa ttgttggaag gagggcagct tgcttcacag
    11881 ccaaccttat cccgttttct ttccagaact gacgaggaaa cagtccatag tttgcgatgc
    11941 ctcaaccttg aattggtcga attcttttta cagtttcacc agctaaacca actcattgta
    12001 gatatcgatt ctacccattt cacaacttat ggcaagcaag aaggtgttgc ttataacgcc
    12061 cactatcgtg ctcatggcta tcatcctctt tatgctttcg aggggaagac aggttattgt
    12121 ttcaatgccc agcttcgtcc tggtaatcgt tattgttctg aagaggcaga cagctttatc
    12181 acacctgttt tagaacggtt taatcaactt ctctttcgaa tggatagtgg ctttgcgacc
    12241 ccaaaattat acgatttaat tgaaaaaaca gggcaatact acctcataaa actcaagaaa
    12301 aatactgttc tgagccgtct tggagacctt tccctccctt gcccacagga tgaggactta
    12361 accatcttgc cccactccgc ctactcagaa actctctatc aagcaggatc ttggtcgcac
    12421 aagcgtcgtg tctgccagtt ctctgaacga aaagaaggaa acttgttcta cgatgttatt
    12481 tctctcgtta caaatatgac gagtggaaca agccaagacc agtttcagct ttatcgtgga
    12541 cgtggtcaag ccgagaattt catcaaggag atgaaggagg gattttttgg cgataaaacg
    12601 gatagttcaa ccttaatcaa aaacgaagtt cgtatgatga tgagctgtat cgcctacaat
    12661 ctctatcttt ttttcaaaca tctagctgga ggtgacttcc aaactttaac aatcaaacgc
    12721 ttccgccatc tttttcttca cgtggtagga aaatgtgttc gaacaggacg caagcagctc
    12781 ctcaacttgt ctagtctcta tgcctattcc gaattgtttt cagcacttta ttctaggatt
    12841 agaaaagtca acctgaatct tcctgttcct tatgaaccac ctagaagaaa agcgtcgtta
    12901 atgatgcatt aaagaacagt cgagatgaaa aaatcgtgtg acgcaccaag ggaggagtct
    12961 gcccttttga ggaaatctag cgaggaaaaa cgatactgga acagcagaaa gtaaaactga
    13021 cctcatgagg aggaagaaag tggctcatga ggtcaggggt tttgtaagtt acatctagtt
    13081 gagagaggta tgaatgattt ggggtttcaa taacctaact aagtttaatt cagttagatt
    13141 tacttgattt tcttggatgc tataatcagg atttttatgt ctagcttttt tatagtaaaa
    13201 atcgaaatct ttttctgtaa cttcaagttg attcactatg tcttttgatg agaatttact
    13261 atttatcaag ttgtgagtct ttttcaattc taattttgtg tcataaatta ctatactatt
    13321 tttaaatcta gttaaaggat atttttcgag accaggtatt gaagaaaata ctttcagcaa
    13381 ttggtacttt aaagtatttt tgtataagca gtgataataa atagtctcct gataatctat
    13441 tttaaaactt tctacttcag gggaagggac tagacaatta ccttgatcta aatacatagc
    13501 catacactcg tcaattgtaa gatgacgata tcgaagttgt actaattgcc aatcaatatt
    13561 agtctggtat tgatttaaac tataagacat agttttgaaa cgatttgcat catcgtcgtt
    13621 aagtttaata taaaaatcgg gattaggatt ataaataaaa aatcttccgt cttcattttc
    13681 aatgaagaac caatttttat agtcttttaa aacatgaaaa tactgctctt tgatatttaa
    13741 gtcggtatga ttaaactttt gaaacaactc atttattaac tcaaaaggag cagaggagtc
    13801 tttaggggta tttatagagc catttctagc atatattaat ccttttggta atgcagtatc
    13861 tttcttaggc ttataatctt ttgttaaaaa tacaggaact ttatctgtat catgaataat
    13921 taagatgtca atttctttgt tgtctatagt ttcagtttgt atgctaattt taatttgatt
    13981 atttgttgat ataaagagtt tatgtagtaa atctgttaga tcttcttcat ttcttctatt
    14041 atcatcattg tttacaccga ttatatctaa agtgatatta tcaattccaa agatgatata
    14101 acaatcttcg tgatgtgatg tattgacaaa atttaagata tcacgcacca attcagtttt
    14161 tgaatgatgc catttttgtt taaaatcatg aaactcatct tcgggtgtat tcaatagtaa
    14221 gtgtatttga tctagactca gcatttttat ttctccaaat attagtttac agaaatttta
    14281 tcatagaatc agagaaagtc aatcataact atattagctg tgataccttt ttcaaatctt
    14341 ccctgttatc ctaatatcat tcatagaaaa tcaatttttg attttctatg ggggtttggg
    14401 ggcgaagtca ccaagttatc ttatcgttgg ctgtcaaaac tagaaagttt tgataggctg
    14461 gcgatatgat ttttgggata ttgtggacac aatatctgag ctcgcaaagc cttacaagaa
    14521 tgaaaatcag ttgttggaaa agtgtactga cattgtatgg tagctcacat tgtcagtaca
    14581 agtattttgg aaaggaagta gcagtatgaa acgagatgtg cgtgatattc ggaaacaatt
    14641 tcgtttaaca gaagcagaag aaaagcaaat tctagctttg atgagagagc ggggagagac
    14701 taatttctct gattttcttc gtaaaagttt actttcctct gatttacaaa aacagatgga
    14761 gacatggttt gccctctggc aatcccaaaa actagaacaa atcagtcgtg acgttcatga
    14821 agttttaatc ttggcacagt cagaacgtca agtcacccaa gagcatgtat ctattctctt
    14881 aacgtgcgtg caggaattga ttcaagaggt tgcaaacacc atacccctca gtaaagaatt
    14941 tcgtgagaag tacatgaggt aagcacatgg aacatcgtta ccgaaccaat ctcaagaaag
    15001 tgtttttgtc tgatagtgag ttgaaccaac taaatataaa tatcgatcaa agtggttgta
    15061 aatccttttc tgaatatgcg agacgaactc tactcgatcc tggtatgaat tttatcacga
    15121 ttgacacaaa cggttaccaa gatttagtgt ttgagttaaa gaggattggc aataatatca
    15181 accagattgc tcgaagtgtt aatcaatctc agttaatttc tggtgaagaa ttgcaggagt
    15241 tgaaaaaagg aattggtgaa ttgataaaag aagttgataa ggaatttaat ctgcaagcgc
    15301 agaagctaaa ggagttccat ggtcatcact aaacactttg ccattcacgg aaagagttac
    15361 cgcagaaagc ttatcaagta cattctcaat cctgagaaaa ccaataatct tgccttggtg
    15421 tcggactatg gcatgaagaa ttttctggac tttcctagct atgaggaaat ggtgcagatg
    15481 tatcatgaaa atttcatcag caacgatacg ctttacgatt ttcgccacga caggatggaa
    15541 gaaaatcaac gaaaaataca cgctcaccac atcattcagt ctttctcgcc agaggatcat
    15601 ctcactcctg aacaaatcaa tcggataggt tatgagactg tgaaggaatt aactggtggc
    15661 aaatttcgtt ttatcgttgc gacccatgtt gataaagacc acctgcacaa tcacatcatt
    15721 atcaattcag tagatagcaa ttctgacaaa aagcttaagt gggactacaa ggtggagcga
    15781 aatcttcgca tgatttctga ccgtttttct aaaatcgcag gtgctaaaat cattgagaac
    15841 cgctattctc accagcggta tgaagtctat cgtaagacta atcacaagta tgaactcaag
    15901 cagcgactct attttttgat ggaacattct agggactttg aggatttcaa aaagaatgct
    15961 ccgctactac atgtggagat ggatttccgt cacaagcatg ccaccttttt tattacggac
    16021 tcaactatga aacaggtggt gcgtggcaag caactcaatc gcaagcagcc ttacacagaa
    16081 gaatttttta agaactactt tgccaaaaga gaaatagaaa gtctcatgga atttttattg
    16141 ctgaaagttg agaatatgga tgatttactt cagaaagcaa aactttttgg actaactatc
    16201 aatcctaaac aaaagcatgt ttcttttcaa tttgcaggag tggaggtaaa ggagacagag
    16261 ctagaccaga aaaatcttta tgatgtagag tttttccaag attattttaa aaatagaaaa
    16321 gattggcaag ctccagaaac tgaggatttc gttcaacttt atcaagaaga aaagttatcc
    16381 aaagaaaaag aacttccaag cgatgagaag ttctgggagt cctatcaaga gttcaagagt
    16441 aacagagatg ccgttcatga atttgaggtg gagttgtcac tcaatcaaat tgaaaaagta
    16501 gtggatgatg gaatttacgt caaggtcaag tttggtattc gtcaggaggg acttatcttt
    16561 gtgccgaaca tgcagcttga tatggaagag gataaggtga aggttttcat cagggaaacc
    16621 agctcctact atgtctacca caaagacgct gccgagaaaa attgttatat gaaaggtcga
    16681 accttaatta gacagttcag ctatgaaaat caaaccattc cattacgcag aaaagcgaca
    16741 gtcgatatga ttaaagagaa gattgcggaa gtggatgctt tgattgaact ggaagtagaa
    16801 aatcaatctt atgtcacgat taaagatgag ttagtgcatg aactagcagc gtctgaattg
    16861 agaatcaatg agttgcaaga acgaatgtca accttgaatc aagtagcaga atatctactg
    16921 gcttcagttg aaagtaagca agaaatgaaa ttaaatcttt caaaactgaa tataactgag
    16981 aatatcagtg ctaatattgt tgagaaaaaa ttgaagagcc tggggaatca actggaattg
    17041 gaaaggggca ggtatgaaaa gatggtagtc aggctagata aatttataaa tcgcttaaat
    17101 acaggacttt caaaaggaga tgggatagat tttcaaaaat aggaatctag ccaataatta
    17161 tatacaatgt gtatcttttg taaaatatat ttgaaattta gatttaatca tgttacaatt
    17221 aacattgaaa tcaaatagaa aaggaagatg caaacgtggg tacactatta gcaacaagat
    17281 taaaaaatag acgaaaagaa ttaaaaatgt ctcagcgaga attagctgag ggtatctgta
    17341 aacaggggca aattagtcga ttagagagtg gagagttcac ccctggagcg gattttttac
    17401 atgcccttgc taagaaatta aaagttagta tggactactt ttttgatgag caggttgtag
    17461 aggaagtcaa tgagttatca gagtttaaga agttagcaca gacatttatc acaaatcgta
    17521 attatgaatc tttaaaatat atatatgaat tggaaaatgt aaaagcccat cgcttatctc
    17581 tagcagataa attttacatg gaatggataa agtctcttat agatttttat ttttatggac
    17641 agaaagaaga ggcaattaca cgattagaga atatgctacc tcagttaaat gtatctgatt
    17701 tgaactatct tcaagtttca aacactctat tcaattttta ttatgatatt gaagatttag
    17761 aacgttttaa tgagattaga gacaagctag agcatcaagt gaatcagctt aatttaaaca
    17821 caattgaaga gttagaacta tcaattaagt tcaattataa cgtttgtcga tacctatggt
    17881 tacagaaaaa tattgaagaa gctattacga aaatcacagc tacgataaag caatgtaagg
    17941 agtacaggac aacttatcta ttagctgatt tgtatttatt gatgggaagt gtaagtgaaa
    18001 atttttcttc taaaagttca gtaaaagaat attttgagac tgctcatttt ctctacaaac
    18061 ttgaggaaaa catgtcaatg gctttgaaag tcgaacatta ttttgcagat ataacagaat
    18121 aaggaatacg gtgttctagt gagcatcgtt ttttaaatct aatttgaata caaaaaagta
    18181 ttaaataaaa aaaaataaaa aaagattata aaaatacttg acaagctaat tttgaagtga
    18241 taaaataaat gcaagaaaac gaaaggagag gtatatgaga agtttgttta ggaaaattgt
    18301 tgctttgtta gtcataggat taatcctatt agggactgct ggaggaactc aagttcataa
    18361 gatggctaga gggattgatc caggtcctgc gaatggtatt tatagatagg agattatagt
    18421 cacttaaaaa tcaaaaaatt ataaaatttt tgttttactt aaatagatat tttatgatgg
    18481 gcgaagtttt tataactagt tcctataagt acagaaacct attttaattt actaatttca
    18541 aaacaatttt ttgagatata tgtaattaaa tctaaattaa gctttaaaaa attattttta
    18601 gcaatttgat tttgaaagtg tcatgcagca atatgaaagc gtagaataga ggtgtttcca
    18661 atgtacaagt aagttttgat tccaaataaa gtaatagaaa aggagctata taatgagtag
    18721 tcaaatgaaa gctttcttga atgaacttca aggaaatatg gaagttgttg gagaattttt
    18781 tgataatcct gaaaaggtaa ttagaaaatt tggaattgtc ggaagagaga aggaagcatt
    18841 gctaatccgt gacttaaatg atatggatga ttatgctctt tcaattcaaa atagcgttgc
    18901 atcgccttct ggggcacata gtagcacttg ccattttgtt agacaagatt tacaa
//
LOCUS       DAVLXH010000041        18740 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00028199
            SAMN33607166-rid17955573.denovo.041, whole genome shotgun sequence.
ACCESSION   DAVLXH010000041 DAVLXH010000000
VERSION     DAVLXH010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607166
            Sequence Read Archive: SRR23725544
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18740)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18740)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721421.1
            Genome Coverage       :: 115x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:42:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,210
            CDSs (total)                      :: 2,161
            Genes (coding)                    :: 2,023
            CDSs (with protein)               :: 2,023
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 73 of 138
            Pseudo Genes (incomplete)         :: 60 of 138
            Pseudo Genes (internal stop)      :: 40 of 138
            Pseudo Genes (multiple problems)  :: 31 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18740
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607166-rid17955573.denovo.041"
                     /strain="AUSMDU00028199"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1349"
     gene            1187..2446
                     /locus_tag="VYO11_001541"
     CDS             1187..2446
                     /locus_tag="VYO11_001541"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HEV1596084.1"
                     /translation="MRKIVINGGLPLQGEITISGAKNSVVALIPAIILADDVVTLDCV
                     PDISDVASLVEIMELMGATVKRYDDVLEIDPRGVQNIPMPYGKINSLRASYYFYGSLL
                     GRFGEATVGLPGGCDLGPRPIDLHLKAFEAMGATASYEGDNMKLSAKDTGLHGASIYM
                     DTVSVGATINTMIAAVKANGRTIIENAAREPEIIDVATLLNNMGAHIRGAGTNIIIID
                     GVERLHGTRHQVIPDRIEAGTYISLAAAVGKGIRINNVLYEHLEGFIAKLEEMGVRMT
                     VSEDSIFVEEQSNLKAINIKTAPYPGFATDLQQPLTPLLLRANGRGTIVDTIYEKRVN
                     HVFELAKMDADISTTNGHILYTGGRDLRGASVKATDLRAGAALVIAGLMAEGKTEITN
                     IEFILRGYSDIIEKLRNLGADIRLVED"
     gene            2462..3013
                     /locus_tag="VYO11_001542"
     CDS             2462..3013
                     /locus_tag="VYO11_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1596085.1"
                     /translation="MNIWTKLAMFSFFETDRLYLRPFFFSDSQDFREIASNPENLQFI
                     FPTQASLEESQYALANYFMKSPLGVWAICDQKNQQMIGSIKFEKLDEIKKEAELGYFL
                     RKDAWSQGFMTEVVRKICQLSFEEFGLKQLSIITHLENEASQRVALKSGFSLFRQFKG
                     SDRYTRKMRDYLEFRYVKGEFNE"
     gene            3006..4283
                     /locus_tag="VYO11_001543"
     CDS             3006..4283
                     /locus_tag="VYO11_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEV1596086.1"
                     /translation="MSKHQEILSYLEELPVGKRVSVRSISNHLGVSDGTAYRAIKEAE
                     NRGIVETRPRSGTIRVKSQKVAIERLTFAEIAEVTSSEVLAGQEGLEREFSKFSIGAM
                     TEQNILSYLHDGGLLIVGDRTRIQLLALENENAVLVTGGFQVHDDVLKLANQKGIPVL
                     RSKHDTFTVATMINKALSNVQIKTDILTVEKLYRPSHEYGFLRETDTVKDYLDLVRKN
                     RSSRFPVINQHQVVVGVVTMRDAGDKSPSTTIDKVMSRSLFLVGLSTNIANVSQRMIA
                     EDFEMVPVVRSNQTLLGVVTRRDVMEKMSRSQVSALPTFSEQIGQKLSYHHDEVVITV
                     EPFMLEKNGVLANGVLAEILTHMTQDLVVNSGRNLIIEQMLIYFLQAVQIDDILRIQA
                     RIIHHTRRSAIIDYDIYHGHQIVSKANVTVKIN"
     gene            4299..5159
                     /locus_tag="VYO11_001544"
     CDS             4299..5159
                     /locus_tag="VYO11_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl aminopeptidase"
                     /protein_id="HEV1596087.1"
                     /translation="MITLKSAREIEAMDKAGDFLASIHIGLRDLIKPGVDMWEVEEYV
                     RRRCKEENFLPLQIGVDGAMMDYPYATCCSLNDEVAHAFPRHYILKDGDLLKVDMVLG
                     GPIAKSDLNVSKLNFNNVEQMKKYTQSYSGGLADSCWAYAVGTPSEEVKNLMDVTKEA
                     MYKGIEQAVVGNRIGDIGAAIQEYAESRGYGVVRDLVGHGVGPTMHEEPMVPNYGIAG
                     RGLRLREGMVLTIEPMINTGDWEIDTDMKTGWAHKTIDGGLSCQYEHQFVITKDGPVI
                     LTSQGEEGTY"
     gene            5538..6322
                     /locus_tag="VYO11_001545"
                     /pseudo
     CDS             5538..6322
                     /locus_tag="VYO11_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
     gene            6513..8804
                     /gene="pcrA"
                     /locus_tag="VYO11_001546"
     CDS             6513..8804
                     /gene="pcrA"
                     /locus_tag="VYO11_001546"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000992850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HEV1596088.1"
                     /translation="MNALLNGMNDRQAEAVQTTEGPLLIMAGAGSGKTRVLTHRIAYL
                     IDEKLVNPWNILAITFTNKAAREMKERAYSLNPATQDCLIATFHSMCVRILRRDADHI
                     GYNRNFTIVDPGEQRTLMKRILKQLNLDPKKWNERTILGTISNAKNDLIDDVAYAAQA
                     GDMYTQIVAQCYTTYQKELRQSESVDFDDLIMLTLRLFDQNPDVLTYYQQKFQYIHVD
                     EYQDTNHAQYQLVKLLASRFKNICVVGDADQSIYGWRGADMQNILDFEKDYPKAKVVL
                     LEENYRSTKTILQAANEVIKNNKNRRPKNLWTQNADGEQIVYYRADDELDEAVFVART
                     IDELSRSQNFLHKDFAVLYRTNAQSRTIEEALLKSNIPYTMVGGTKFYSRKEIRDIIA
                     YLNLIANLSDNISFERIINEPKRGIGPGTVEKIRDFANLQNMSMLDASANIMLSGIKG
                     KAAQSIWDFANMMLDLREQLDHLSITELVESVLEKTGYVDILNAQATLESKARVENIE
                     EFLSVTKNFDDTTDVTEEETGLDKLSRFLNDLALIADTDSGSQETSEVTLMTLHAAKG
                     LEFPVVFLIGMEENVFPLSRATEDPDELEEERRLAYVGITRAEKILYLTNANSRLLFG
                     RTNYNRPTRFINEISSDLLEYQGLARPANTSFKASYSSGSISFGQGMSLAQALQDRKR
                     GAAPKSIQSSGLPFGQFTAGAKPASSEANWSIGDIALHKKWGEGTVLEVSGSGARQEL
                     KINFPEVGLKKLLASVAPIEKKI"
     gene            8847..9527
                     /gene="radC"
                     /locus_tag="VYO11_001547"
     CDS             8847..9527
                     /gene="radC"
                     /locus_tag="VYO11_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000286923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HEV1596089.1"
                     /translation="MYSISFQEDSLLPRERLAKEGVEALSNQELLAILLRTGTRQASV
                     FEIAQKVLNNLSSLTDLKKMTLQELQSLSGIGRVKAIELQAMIELGHRIHKHETLEME
                     SILSSQKLAKKMQQELGDKKQEHLVALYLNTQNQIIHQQTIFIGSVTRSIAEPREILH
                     YAIKHMATSLILVHNHPSGAVAPSQNDDHVTKLVKEACELMGIVLLDHLIVSHSNYFS
                     YREKTDLI"
     gene            complement(9524..10213)
                     /locus_tag="VYO11_001548"
     CDS             complement(9524..10213)
                     /locus_tag="VYO11_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HEV1596090.1"
                     /translation="MKKPVIGITGNEKAHPDDDIMMSYAAKGFVEGVKDAGGIPIILP
                     IGDQEMACHYISLIDKLILTGGQNVDPKFYGEPKTIDSDDYHLQRDIFELALIKEAIK
                     QKKPIFSVCRGTQLFNVAMGGTLYQDIEDHWQDSSVEYTTQRLVTEPDTVLQEIYGEI
                     SHINSFHHQSIKDLAPNLKVVAHDPKDGIIEAVMSTDDVAFLGVQWHPELLFENRPKD
                     KKLFDYVVNEL"
     gene            complement(10231..10872)
                     /locus_tag="VYO11_001549"
     CDS             complement(10231..10872)
                     /locus_tag="VYO11_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HEV1596091.1"
                     /translation="MKDKQFAIPKATAKRLSLYYRIFKRFHAEKIERANSKQIAEAIG
                     IDSATVRRDFSYFGELGRRGFGYDVKKLMTFFADLLNDNSITNVMLVGIGNMGHALLH
                     YRFHERNKMKIIMAFDLDDHPEVGTQTPDGIPIYGISQIKDKIKDADVKTAILTVPSV
                     KSQEVANLLVDAGVKGILSFSPVHLHLPKDVVVQYVDLTSELQTLLYFMRKED"
     gene            complement(10955..11170)
                     /locus_tag="VYO11_001550"
     CDS             complement(10955..11170)
                     /locus_tag="VYO11_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HEV1596092.1"
                     /translation="MFELTYKDCYHVERTLKYEDHEALMLTLSGCVTLPDTLYVTSLT
                     FRGQKVYQGLVGDLYRFLSHADFLHQN"
     gene            complement(11178..11525)
                     /locus_tag="VYO11_001551"
     CDS             complement(11178..11525)
                     /locus_tag="VYO11_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HEV1596093.1"
                     /translation="MAFEKIIQLKNCRYDYTLSPSVKKFTLKDNTFFETKVGNYELTR
                     LLEKVPNSGEGFQLKIIINKELTGAKINITDKFGLRLVDIFKSEDHHIHQEKFYFLMD
                     SLVERGVFTKSER"
     gene            complement(11530..12645)
                     /locus_tag="VYO11_001552"
     CDS             complement(11530..12645)
                     /locus_tag="VYO11_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEV1596094.1"
                     /translation="MIYLDNAATTPMSAVAISAMTKVMQETHGNPSSIHGHGRQAGKL
                     LREARQELAQLLRTKPQHIFFTSGGTEGNNTTIIGYCLRHQEQGKHIITTAIEHHAVL
                     ETIDYLVQHFGFEATIIQPENQEITAQQIQKALRDDTILVSTMFANNETGNLLPIAEI
                     GQILKQHPAAYHVDAVQAIGKIPIHSEELGIDFLTASAHKFHGPKGIGFLYASSMDFD
                     SYLHGGDQEQKKRAGTENLPAIVGMVAALKEDLEKQEEHFQHVQNLETAFLAELEGIQ
                     YYLNRGKHHLPYVLNIGFPGQKNDLLLLRLDLAGISISTGSACTAGVVQSSHVLEAMY
                     GANSERLKESLRISLSPQNTVEDLQTLAKTLKEIIGG"
     gene            complement(12655..13614)
                     /locus_tag="VYO11_001553"
     CDS             complement(12655..13614)
                     /locus_tag="VYO11_001553"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEV1596095.1"
                     /translation="MSDRKNMKLFALNSNQEIAQKIAQAVGVPLGKLSSRQFSDGEIQ
                     VNIEESVRGYDVYIIQSTSFPVNNHLMELLIMVDACVRASAHSINVVLPYFGYARQDR
                     IACPREPLTAKLVANMLVKAGVDRILTLDLHAVQVQGFFDIPVDNLFTVPLFAKHYCD
                     KGLLGSDVVVVSPKNSGVKRARSLAEYLDAPIAIIDYPQDDATRNEGYIIGDVEGKKA
                     ILIDDILNTGRTFSEASKIVEREGATEIYAVSSHGLFVEGAAELLDNTNIKEILVTDS
                     VATKEKTPKNVCYITASELIGDAIVRIHERKPVSPLFAYNKKK"
     gene            complement(13727..14296)
                     /locus_tag="VYO11_001554"
     CDS             complement(13727..14296)
                     /locus_tag="VYO11_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HEV1596096.1"
                     /translation="MKHLEIELKTLLKKDEYNRLKDQFTGVTPVLQTNYYIDTPDFEL
                     REKKVAMRIRTFEDWAELTLKVPQSVGNMEYNQKLQLKDAENYLSKEELPQGLVLDEL
                     AKHGIQIKNWQVLGCLTTLRYEMKTAIGLMALDQSRYFDMTDYELELEVENHEQGKQD
                     FRQFLEKNQISYQKAPSKLVRFVKSMKNS"
     gene            14424..15095
                     /locus_tag="VYO11_001555"
     CDS             14424..15095
                     /locus_tag="VYO11_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HEV1596097.1"
                     /translation="MTLEWEEFLDPYIQAVGELKIKLRGIRKQYRKQNKHSPIEFVTG
                     RVKPIESIKEKMARRGITYATLEHDLQDIAGLRVMVQFVDDVKEVVDILHKRQDMRII
                     QERDYITHRKASGYRSYHVVVEYTVDTINGAKTILAEIQIRTLAMNFWATIEHSLNYK
                     YQGDFPDEIKKRLEITARIAHQLDEEMGEIRDDIQEAQALFDPLSRKLNDGVGNSDDT
                     DEEYR"
     gene            15079..15897
                     /locus_tag="VYO11_001556"
     CDS             15079..15897
                     /locus_tag="VYO11_001556"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HEV1596098.1"
                     /translation="MKNTGKRIDLIANRKPQSQRVLYELRDRLKRNQFILNDTNPDIV
                     ISIGGDGMLLSAFHKYENQLEKVRFIGLHTGHLGFYTDYRDFELDKLVTNLQLDTGAR
                     VSYPVLNVKVFLENGEVKIFRALNEASIRRSDRTMVADIVINGVPFERFRGDGLTVST
                     PTGSTAYNKSLGGAVLHPTIEALQLTEIASLNNRVYRTLGSSIIVPKKDKIELIPTRN
                     DYHTISVDNSVYSFRNIERIEYQIAHHKIHFVATPSHTSFWNRVKDAFIGEVDE"
     gene            15894..16790
                     /locus_tag="VYO11_001557"
     CDS             15894..16790
                     /locus_tag="VYO11_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEV1596099.1"
                     /translation="MRFEFIADEHVKVKTFLKKHEVSKGLLAKIKFRGGAILVNNQPQ
                     NATYLLDVGDYVTIDIPAEKGFETLEAIELPLDILYEDDHFLVLNKPYGVASIPSVNH
                     SNTIANFIKGYYVKQNYENQQVHIVTRLDRDTSGLMLFAKHGYAHARLDKQLQKKSIE
                     KRYFALVKGDGHLEPEGEIIAPIARDEDSIITRRVAKGGKYAHTSYKIVASYGNIHLV
                     YIHLHTGRTHQIRVHFSHIGFPLLGDDLYGGSLEDGIQRQALHCHYLSFYHPFLEQDL
                     QLESPLPDDFSNLITQLSTNTL"
     gene            16834..17808
                     /gene="pta"
                     /locus_tag="VYO11_001558"
     CDS             16834..17808
                     /gene="pta"
                     /locus_tag="VYO11_001558"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HEV1596100.1"
                     /translation="MEVFESLKANLVGKNARIVLPEGEEPRILQATKRLVKETEVIPV
                     LLGNPEKIKIYLEIEGIMDGYEVIDPQHYPQFEEMVSALVERRKGKMTEEDVRKVLVE
                     DVNYFGVMLVYLGLVDGMVSGAIHSTASTVRPALQIIKTRPNVTRTSGAFLMVRGTER
                     YLFGDCAININPDAEALAEIAINSAITAKMFGIEPKIAMLSYSTKGSGFGESVDKVVE
                     ATKIAHDLRPDLEIDGELQFDAAFVPETAALKAPGSTVAGQANVFIFPGIEAGNIGYK
                     MAERLGGFAAVGPVLQGLNKPVNDLSRGCNADDVYKLTLITAAQAVHQ"
     gene            complement(18208..18507)
                     /locus_tag="VYO11_001559"
     CDS             complement(18208..18507)
                     /locus_tag="VYO11_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HEV1596101.1"
                     /translation="MMNMQNMMRQAQKLQKQMEQSQAELAAMQFVGKSAQDLVQATLT
                     GDKKVVSIDFNPAVVDPEDLETLSDMTVQAINSALEQIDETTKKKLGAFAGKLPF"
BASE COUNT         5540 a         3417 c         4076 g         5707 t
ORIGIN      
        1 gagttgtttt gtcgcttttc attataggtc atatgggact ttttttctac acaaaaatag
       61 gctccataat atctatagtg gatttaccca ctacaaatat tatagagcca aaatcccgtg
      121 cctcatcagg cacgggattt tgtggtacga cgggcatgta tagcaaactg aatctggaat
      181 agcgcagcat atcttctaaa atattgctat aaattgattt gaatttcaaa attaaattgt
      241 tttattctta tttcaatttg ttatagtata tctgatgtca aagttctcgg cgagtcaaat
      301 agtgattccc aagcctgact atcgtgaggt agcggattaa aatggtctgg ggatagaccg
      361 ttttaagtct gatgctggaa ataagaattg tcagaagaag ggatagcgaa atcgtggctc
      421 tacgaacagg aacgtgataa taaggcgtat atagcgaata agggggccaa aagcactaaa
      481 gtccaaaaag gtagtcgtaa cctatatgcg taaatcatga gagtaattga attcgtacta
      541 agattttcta tttttactgt aaccttttaa cgtcctcata tcttgtatac acaaggaaag
      601 atgtacgact tatcccgtga ggtctatcac tataaagaga aaacgacaga tagaagtgat
      661 cctgagtcac ggttatcttt aaaatagatt gtctgatagg atgctagcct gaaaacgtct
      721 tgttcatgaa atataggacg gtatgtataa aacgcttctg tgaactgaga gaagggggag
      781 aagttcttgc taaaatttag ttgaacagcc gtattccgat acttagataa gagatctagt
      841 cttagctcct actcagtttc aggggataaa aaaggggcaa tagcgattcg agaaagatta
      901 tactcttcga aaatctcttc aaatcacgtc aatatcgcct tgccgtatgt gtaggatact
      961 aactacgtca gttccatcta caatctcaaa acagtgtttt gagcaacctg cggctagttt
     1021 cctagtttga tctttgattt ttattgagta ttagtaattc agttactaac tcgtcaactc
     1081 tgatttatcc aataaaattg aaaaggatgg aaaaaaggat aaatttatga tatactttat
     1141 tttgaagacc ttattagaaa tcttgaaaga gtattgaaaa cttagaatga gaaaaattgt
     1201 tatcaatggt ggattaccac tgcaaggtga aatcactatt agtggtgcta aaaatagtgt
     1261 cgttgcctta attccagcta ttatcttggc tgatgatgtg gtgactttgg attgcgttcc
     1321 agatatttcg gatgtagcca gtcttgtcga aatcatggaa ttgatgggag ctactgttaa
     1381 gcgttatgac gatgtattgg agattgaccc aagaggtgtt caaaatattc caatgcctta
     1441 tggtaaaatt aacagtcttc gtgcatctta ctatttttat gggagcctct taggccgttt
     1501 tggtgaagcg acagttggtc taccgggagg atgtgatctt ggtcctcgtc cgattgactt
     1561 acaccttaag gcgtttgaag ctatgggtgc cactgctagc tacgagggag ataacatgaa
     1621 gttatctgct aaagatacag gacttcatgg tgcaagtatt tacatggata cggttagtgt
     1681 gggagcaacg attaatacga tgattgctgc ggttaaagca aatggtcgta ctattattga
     1741 aaatgcagcc cgtgaacctg agattattga tgtagctact ctcttgaata atatgggtgc
     1801 ccatatccgt ggggcaggaa ctaatatcat cattattgat ggtgttgaaa gattacatgg
     1861 gacacgtcat caggtgattc cagaccgcat tgaagctgga acatatatat ctttagctgc
     1921 tgcagttggt aaaggaattc gtataaataa tgttctttac gaacacctgg aagggtttat
     1981 tgctaagttg gaagaaatgg gagtgagaat gactgtatct gaagacagca tttttgtcga
     2041 ggaacagtct aatttgaaag caatcaatat taagacagct ccttacccag gctttgcaac
     2101 tgatttgcaa caaccgctta cccctctttt actaagagcg aatggtcgtg gtacaattgt
     2161 cgatacgatt tacgaaaaac gtgtaaatca tgtttttgaa ctagcaaaga tggatgcgga
     2221 tatttcgaca acaaatggtc atattttgta cacgggtgga cgtgatttac gtggggccag
     2281 tgttaaagcg accgacttaa gagctggggc tgcactagtc attgctgggc ttatggctga
     2341 aggtaaaact gaaattacca atatcgagtt tatcttacgt ggttattctg atattatcga
     2401 aaaattacgt aatttaggag cggatattag acttgttgag gattaaaccg tagaggtgtt
     2461 tatgaatatt tggaccaaat tagcaatgtt ttcttttttt gaaacggatc gcttgtattt
     2521 gcgtcctttc ttttttagtg atagtcagga cttccgcgag atagcttcaa atccagaaaa
     2581 tcttcaattt attttcccaa cgcaggcaag tctggaagaa agtcaatatg cactggccaa
     2641 ttactttatg aagtcccctt tgggagtgtg ggcaatttgt gaccagaaaa atcaacaaat
     2701 gattggttct attaaatttg agaagttaga tgaaatcaaa aaagaagctg agcttggcta
     2761 ttttttgaga aaagatgctt ggtcgcaagg atttatgaca gaggttgtta gaaaaatttg
     2821 tcagctttct tttgaggaat ttggcttaaa acaattatct atcattaccc accttgaaaa
     2881 tgaagctagc caaagagttg ctcttaagtc tggatttagt ttgttccgtc agtttaaggg
     2941 aagtgatcgt tacacaagaa aaatgcggga ttatcttgaa tttcggtatg taaaaggaga
     3001 gttcaatgag taagcatcag gaaattctaa gctatttgga ggaattacca gtaggtaaaa
     3061 gggtcagtgt tcgtagcatt tcgaatcatc taggagttag tgatggaaca gcctatcggg
     3121 ctattaaaga agctgaaaac cgtggaattg tggagacccg tcctagaagt ggaacaattc
     3181 gtgttaaatc ccagaaagtt gctatagaga gattaacgtt tgctgaaatt gcagaagtga
     3241 cttcttctga ggttctggct gggcaagaag gtttagagag agagtttagt aagttttcaa
     3301 ttggtgccat gactgaacaa aatatcttgt cttaccttca tgatgggggg ctcttgattg
     3361 tcggagaccg aacccgtatt cagttgctag ccttggaaaa tgaaaatgca gttctggtta
     3421 cagggggatt tcaggttcat gatgatgtgc ttaaactggc caatcaaaaa gggattcctg
     3481 ttctaagaag taagcatgat acctttaccg tcgcgaccat gatcaataaa gccttgtcaa
     3541 atgtccaaat caagactgat attctgacag ttgagaaact ttatcgccct agtcatgagt
     3601 atggttttct gagagagaca gatacagtta aagattattt ggacttggtt cgtaagaatc
     3661 gtagcagccg tttccctgtt atcaatcaac atcaggtcgt tgttggcgtt gtaaccatga
     3721 gagacgctgg tgataaatca ccaagcacga caattgataa ggttatgtct cgtagtctat
     3781 ttttggttgg gttatcgaca aatattgcca atgtgagtca acggatgatc gcagaagact
     3841 ttgaaatggt accagttgtt cgaagcaatc aaactttgct tggcgttgtg acgcgacgag
     3901 atgtcatgga gaagatgagc cgttcccaag tttcggctct accaactttt tctgagcaga
     3961 ttggacaaaa gctctcttat caccatgatg aagtagtcat tacagtggaa ccctttatgc
     4021 tagaaaaaaa tggagttttg gctaatggtg tattggcaga aattctgacc cacatgaccc
     4081 aagatttagt tgttaatagt ggtcgcaatc tcattatcga gcagatgcta atctactttt
     4141 tgcaggctgt tcagatagat gatatattgc gcattcaggc acggattatt catcatacga
     4201 gacggtcagc tataattgat tacgatattt atcatggtca ccagattgtt tcaaaagcaa
     4261 atgtgactgt taaaattaat tagaaactag gagaaaagat gataacatta aaatcagctc
     4321 gtgaaatcga agctatggac aaggctggtg attttctagc aagtattcat ataggcttac
     4381 gtgatttgat taagccaggc gtagatatgt gggaagttga agaatatgtc cgccgtcgtt
     4441 gtaaagaaga aaatttcctt ccacttcaga ttggggttga cggtgccatg atggactatc
     4501 cttatgctac ctgttgctct cttaacgatg aagtggctca cgctttccct cgtcattata
     4561 tcttgaaaga tggtgatttg ctcaaagttg atatggtttt gggaggtccc attgctaaat
     4621 ctgacctgaa tgtctcaaaa ttaaacttca acaatgttga acaaatgaaa aaatacactc
     4681 agagctattc tggtggttta gcagactcat gttgggctta tgctgttggt acaccgtccg
     4741 aagaagtcaa aaacttgatg gatgtaacca aagaagctat gtacaagggt attgagcaag
     4801 ctgttgttgg aaatcgtatc ggtgatatcg gtgcggctat tcaagaatac gctgaaagtc
     4861 gtggttacgg tgtagtgcgt gatttggttg gtcatggtgt tggcccaact atgcacgaag
     4921 aaccaatggt tcctaactat ggtattgcag gtcgtggact ccgtcttcgt gaaggaatgg
     4981 tcttaaccat tgaaccaatg atcaatacag gcgattggga aattgataca gatatgaaaa
     5041 ctggttgggc gcataagacc attgacggtg gattgtcatg tcagtatgaa caccaatttg
     5101 tcattacgaa agatggacct gttatcttga ctagccaagg tgaagaagga acttattaat
     5161 aaaaagtgaa aagactactg gaagtttatt atgaaaaaat ccagtagatc ttttcataat
     5221 aaaacgcatt gtatcaagtg ttaggggctg atatcatgcg tttttctgct tttaagattt
     5281 tttccaactc tgtttgtaag cgcatcataa caaagggtct aggattcagg gctctcctcc
     5341 tatatactat tagtaaagta aaactaaggg aggatatttt agtgtcgcag tctattgttc
     5401 ctgtagagat tccacaatat tgtcgttttg attctaaaaa gagaaatgga attctgttta
     5461 atgttcgtat tgccaatctt aaatttacct tttttagatt agacttcctg cgaaacaaaa
     5521 tatggtatag tagttctatg aatgatgaag caagtaaaca actaactgat gcacgattta
     5581 agcgtcttgt tggtgttcag cgtaccactt ttgaagagat gttagctgta ttaaaacagc
     5641 ttatcaactt aaacacgcaa aaggtggacg aaaacctaaa ttaagcctgg aagaccttct
     5701 tatggccact cttcaatatg tgcgagaata tcgcacttat gaacaaattg cggctgattt
     5761 tggtattcac gaaagcaact tactccgtcg gagccaatgg gttgaagtaa ctcttgttca
     5821 aagcggtttt acgatttcaa gagctcctct cagttctgag gacacggtaa tgattgatgc
     5881 gacggaagta caaatcaatc gccctaaaaa aacaattagc gaatgattct ggtaaaaaga
     5941 aatttcatgc tatgaaggct caagcgattg tcacaagtca agggagaatt gtttctattg
     6001 tcatgatatg aagttgttca aaatgagtcg cggaaatatc ggacaagctg gtaaaatctt
     6061 ggctgacagt ggttatcaag ggctcatgaa gatatatcct caagcacaaa ctccacgtaa
     6121 atccagcaaa ctcaagtcgc taatagctga agataaagcc tataaccatg cgctatctaa
     6181 ggagagaagc atggttgaga acatctttgc caaagtagaa acgtttaaaa tgttttcaac
     6241 aacctatcga aatcatcgta aatgcttcgg attacgaatg aatttgattg ctggtattat
     6301 caatcatgaa ctaggattct agttttgcag gaagtctatt gaggtattga gctagtttat
     6361 gaaaaaattg agtgaaaagt cgagtgtttt agaaacccac agtgtagtat tctagtttca
     6421 atccactata ttttgctact ccccgtaaag tttctatttt ccctgatttc tgatataata
     6481 gaaatattga cttcaagagt aaggaagaga agatgaacgc attattaaat ggaatgaatg
     6541 accgtcaggc tgaggcggtg caaacgacag aaggtccctt gctaatcatg gcaggagctg
     6601 gttctggaaa gactcgtgtt ttaacccacc gtatcgctta tttgattgat gaaaagctgg
     6661 tcaatccttg gaatatcttg gccattacct ttaccaacaa ggctgcgcgt gagatgaaag
     6721 agcgtgctta tagcctcaat ccagctactc aggactgtct gattgcgacc ttccactcca
     6781 tgtgtgtgcg tattttgcgt cgcgatgcgg accatattgg ctacaatcgt aattttacaa
     6841 ttgtggatcc tggtgaacag cgaacgctca tgaaacgtat tctcaaacag ttgaacttgg
     6901 atcctaaaaa atggaatgaa cgaactattt tggggaccat ttccaatgct aagaatgatt
     6961 tgattgatga tgttgcttat gctgcccaag ctggcgatat gtatacgcaa attgtggccc
     7021 agtgttatac aacctatcaa aaagaacttc gtcagtctga atccgttgac tttgatgatt
     7081 tgattatgct gaccttgcgt ctctttgatc aaaatcctga tgttttgacc tactaccagc
     7141 aaaaattcca atacatccac gttgatgagt accaagatac caaccacgct cagtaccaat
     7201 tggtcaaact cttggcttcc cgttttaaaa atatctgtgt ggttggggat gcggaccagt
     7261 ctatctacgg ttggcgtggt gctgatatgc agaatatctt ggactttgaa aaggattacc
     7321 ccaaagctaa ggttgttttg ttggaggaaa attaccgctc aaccaaaacc attctccaag
     7381 cggccaacga ggttattaaa aataataaaa atcgccgtcc taaaaatctc tggactcaaa
     7441 acgctgatgg ggagcaaatc gtttactatc gtgccgatga tgagctggat gaggctgtat
     7501 ttgtagccag aaccatcgat gaacttagtc gcagtcaaaa cttccttcat aaggattttg
     7561 cagttctcta tcggactaat gcccagtccc gtacaattga ggaagccctg ctcaagtcta
     7621 acattcctta taccatggtt ggcggaacca aattctacag ccgtaaggaa attcgcgata
     7681 ttattgctta tctcaacctt attgctaatt tgagtgacaa tattagtttt gagcgtatta
     7741 tcaacgagcc taaacgtgga attggtccag gtacagttga gaaaatccgt gattttgcaa
     7801 atttgcaaaa tatgtctatg ctggatgctt ctgctaatat tatgttgtct ggtatcaagg
     7861 gtaaggcagc ccaatctatc tgggattttg ccaatatgat gcttgatttg cgggagcagc
     7921 tagaccactt aagcattaca gagttggttg agtccgtcct agaaaaaaca ggttatgtcg
     7981 atattcttaa cgcccaagcg actctagaaa gcaaggctcg ggttgaaaat atcgaagagt
     8041 ttctttctgt tacgaagaac tttgatgaca ccactgatgt gacagaagag gaaactggtc
     8101 tggacaaact gagtcgtttc ttaaatgact tggctttgat tgccgacaca gattcaggta
     8161 gtcaggagac atcagaagtg accttgatga ccctgcatgc tgccaaaggt ctcgaatttc
     8221 cagttgtctt tttgattggg atggaagaaa atgtctttcc acttagtcgt gcgactgaag
     8281 atccagatga attagaagaa gagcgccgtc tagcctatgt aggtatcacg cgtgcagaga
     8341 aaattctcta tctgaccaat gccaactcac gcttgctttt tggtcgtacc aattataacc
     8401 gtccgactcg ttttattaac gaaatcagtt cagacttgct tgagtatcaa ggtctggctc
     8461 gtcctgcaaa tacaagcttt aaggcatcat atagcagtgg tagtatttcc tttggtcaag
     8521 gtatgagttt ggctcaggct cttcaagacc gtaaacgcgg tgctgcccca aaatcaatcc
     8581 agtcaagcgg tcttccattt ggtcaattta cagctggcgc aaaaccagca tctagcgagg
     8641 caaattggtc cattggtgac attgctctcc acaagaaatg gggagaggga actgttctgg
     8701 aagtttcagg tagcggtgct aggcaggaat tgaaaatcaa tttcccagaa gtaggtttga
     8761 aaaaactttt agccagtgtg gctccaattg agaaaaaaat ctaattttcc atccttctca
     8821 cgaataataa agtgaggagg atttttatgt acagtatttc attccaagaa gattcactat
     8881 taccaagaga aaggctggcc aaggaaggag ttgaagcgct tagtaaccaa gagttgctag
     8941 ctattttact caggacagga acacgtcaag ctagcgtttt tgaaattgcc caaaaagtct
     9001 tgaacaatct ttcaagccta acggatttga aaaaaatgac cctgcaggaa ttgcagagtt
     9061 tgtctggtat tgggcgtgtt aaggccatag aattacaagc tatgattgaa ctggggcatc
     9121 gtattcacaa acacgagact cttgaaatgg aaagtattct cagcagtcaa aagttggcca
     9181 agaagatgca gcaggaatta ggggataaaa aacaagagca cctggtggca ctctatctca
     9241 atactcaaaa tcaaatcatc catcagcaga ccatttttat cggttctgta actcgtagta
     9301 tcgctgaacc gcgagagatt cttcactatg caatcaagca tatggcgact tctcttatct
     9361 tggtccacaa tcatccttca ggagcggtag cgcctagcca aaatgatgat catgtcacta
     9421 aacttgttaa agaagcctgc gaactgatgg ggattgttct cttggaccat ttgattgtct
     9481 ctcattctaa ttactttagt tatcgtgaaa agacagattt aatctaaagt tcattaacga
     9541 catagtcaaa gagtttttta tctttgggac gattttcaaa aagaagttct ggatgccatt
     9601 ggacaccgag aaaggcgaca tcatccgtac tcatgacagc ctcaatgata ccatctttag
     9661 gatcatgagc cacaactttt aaatttggtg ctaagtcctt gatgctctgg tggtggaagg
     9721 agttgatatg agagatttct ccatagattt cttggagaac ggtatctggt tctgttacca
     9781 agcgttgagt tgtgtactca acagaagaat cctgccaatg gtcttcgata tcttggtaca
     9841 aagttccacc catggcaacg ttaaagagtt gggtaccacg gcagacagag aaaatgggct
     9901 ttttctgttt aatagcttcc ttgatgaggg ccagttcgaa gatatctctt tgaaggtgat
     9961 agtcatcgct atcaatggtt ttgggttcgc catagaattt tggatcgaca ttttgcccac
    10021 ctgtcaagat gagcttgtca atcaaactga tatagtggca ggccatttct tgatcaccaa
    10081 tcggtaggat gatgggaatc cctccagcat ctttaacgcc ttcaacaaag ccttttgctg
    10141 cgtagctcat catgatgtca tcatctggat gagctttttc gtttcctgta atcccaataa
    10201 ctggtttttt cataaaatga ttttcgcttt ctaatcctct tttcgcatga agtagaggag
    10261 ggtttggagt tcacttgtca aatcgacata ctgaacgacc acgtcttttg gtaaatgcag
    10321 atggactggt gaaaaactga gaattccttt cacaccagca tcaaccaaga gattagcaac
    10381 ctcttgtgac ttgacgctgg gaacagttag gatagcagtc ttcacatcag catccttgat
    10441 tttatccttg atctgagaaa tcccgtaaat gggaatcccg tcaggagttt gggtaccgac
    10501 ttcaggatgg tcgtctaggt caaaggccat gataatcttc atcttgttac gttcgtggaa
    10561 gcggtagtgg agaagggcat ggcccatatt tccaatacca accagcatga cattggtaat
    10621 agagttgtca ttgagcaaat cggcaaaaaa tgtcattagt tttttgacat catagccaaa
    10681 accacgacga ccaagttcac caaaatagga aaaatcacga cgtacggtcg ctgaatcaat
    10741 accgatagcc tctgcaattt gcttagagtt ggcacgttca atcttttctg catgaaatct
    10801 cttaaaaatt cgatagtaga gagagagtct ttttgctgta gcttttggaa tagcaaactg
    10861 tttatctttc acaaaatcac aacctttcta ttcttctatt ttatagaaac attgtgaaaa
    10921 aatcaacaaa aataagaaaa aactaagaaa aatcttagtt ttgatgtaaa aaatctgcat
    10981 gagatagaaa acggtagagg tctccgacca gaccctgata aactttttgg cccctaaaag
    11041 tcagagaagt cacataaagt gtatctggta aggttacaca tcctgacaaa gtcaacatga
    11101 gagcctcatg atcctcatac ttgagagtac gctctacatg atagcagtcc ttataggtca
    11161 gttcaaacat tttggctcta tctttccgat tttgtaaaga caccacgttc taccaagcta
    11221 tccatgagga agtagaattt ttcctgatga atatggtggt cttctgattt gaaaatatca
    11281 actagacgaa ggccaaactt gtcagtgata ttgattttag cccctgtaag ttccttgtta
    11341 atgatgattt tgagttggaa gccttcaccg ctgtttggca ctttttccaa aaggcgagtc
    11401 agttcatagt taccaacctt agtttcaaaa aaggtgttat ctttgagggt gaatttttta
    11461 acagaagggc taagagtgta atcgtaacga caatttttta actgaatgat tttttcaaat
    11521 gccatatggc taacctccga taatttcttt taaggttttt gcgagggttt gtaggtcttc
    11581 aacggtattt tgtggcgaca aactgatgcg aagggattcc ttcaagcgtt ctgaatttgc
    11641 gccatacatg gcttcaagaa catggctgga ttggacaacg cctgcagtac aggctgagcc
    11701 agtagagatt gaaattccag ctaaatctag ccgaaggagt aagaggtcat ttttctgacc
    11761 aggaaatcca atattgagaa cataagggag atgatgtttt cctctattca agtaatactg
    11821 aatgccctcc agctctgcca gaaaggcagt ttctagattt tgtacatgtt gaaaatgttc
    11881 ttcttgtttt tctaggtctt cttttagggc tgcaaccatg cctacgatag caggcagatt
    11941 ttcagttcct gcacgttttt tctgttcctg gtctccgcca tgtagatagg aatcaaagtc
    12001 catgctagat gcgtagagaa aaccgattcc cttaggacca tggaatttgt gggcagaagc
    12061 agtgagaaaa tcaatgccca attcttctga atgaattggg attttaccaa tagcctgaac
    12121 tgcatcaaca tgataggcag cagggtgttg cttgagtatt tggccaattt cagcgatggg
    12181 cagtaggttt cctgtctcat tattggcaaa catggtagaa accaaaatcg tatcgtcacg
    12241 taaagccttt tgaatttgct gggctgtgat ttcttgattt tctggctgga taatggttgc
    12301 ttcaaaccca aagtgttgaa ccaagtaatc aattgtttca aggacagcat ggtgctcgat
    12361 ggcagttgtg atgatatgtt ttccttgttc ttggtgacga agacagtagc caatgatggt
    12421 agtattattg ccttcagtcc caccagaagt gaaaaagata tgttgaggtt ttgtccttag
    12481 taactgggct agttcctgac gggcttctcg caagagtttg ccagcttgac gaccatgacc
    12541 atgaatacta gaaggatttc cgtgggtttc ttgcataacc ttggtcatag ctgaaatagc
    12601 aactgctgac ataggagtcg ttgcagcatt gtccaaataa atcaaagaat caccttattt
    12661 ctttttattg taggcaaaga gtgggctgac tggttttctt tcgtgaatac ggacgatagc
    12721 atcaccaatt aactcactag cagtgatgta gcatacattt ttaggagttt tttcttttgt
    12781 tgctactgaa tcagtcacaa gaatttcttt aatattagta ttgtcaagaa gctcagcagc
    12841 tccctcgacg aagagaccgt ggctagaaac agcataaatt tctgtagctc cttcacgttc
    12901 aacgatttta gaagcttcag agaaggtacg tcctgtattt aaaatatcat caatcaagat
    12961 agctttctta ccttcaacat caccaataat ataaccttcg ttacgagttg catcgtcttg
    13021 agggtagtcg ataatggcga taggagcatc aagatattca gccaggctac gcgcacgttt
    13081 gacacctgaa tttttagggc taacgacaac aacatctgaa ccaagcaatc ctttatcgca
    13141 gtaatgtttt gcgaataggg gaacagtgaa aagattatcc actggaatat caaagaaacc
    13201 ttgaacctga acggcatgca aatcaagagt caggatacga tcaactccag ccttaaccag
    13261 catattggca actagttttg ctgtaagtgg ctcacgagga caagcaatgc ggtcttgacg
    13321 tgcatagcca aaatatggaa ggacaacgtt gatactgtgg gcacttgcac gcacacaagc
    13381 atcgaccatg attaacaatt ccattaggtg gttgttgaca gggaaacttg ttgattggat
    13441 gatgtaaaca tcataaccac ggacactttc ttcgatattt acttggattt ctccgtctga
    13501 aaattgacgt gatgatagtt ttccaagtgg gacaccaaca gcttgggcaa ttttctgtgc
    13561 aatctcttgg ttagagttga gtgcgaaaag tttcatgttt tttctatctg acattataga
    13621 ccgtcctctg taaactttat aaatcctagt tatatttacc ttacatatat gaactggagt
    13681 ttgtgtattt ttatcttttc tattttacca aaaaatggag attatttcag ctatttttca
    13741 tacttttgac aaatcgaacc aattttgaag gagctttttg gtaggaaatc tgatttttct
    13801 ctaaaaattg tcggaaatcc tgtttgcctt gctcatgatt ttccacttca agctccaatt
    13861 cgtaatctgt catatcaaag tatcggctct gatccagtgc catgagacca atagctgttt
    13921 tcatttcata gcgaagcgtt gttagacaac caagaacctg ccagttctta atttggatac
    13981 catgtttcgc caattcatcc agtactagcc cttgaggaag ttcttcctta ctcagatagt
    14041 tctcagcatc ttttagttgc aatttttggt tgtattccat gtttccaaca ctctgcggga
    14101 ctttgagtgt caactcagcc cagtcttcaa aggttcgaat gcgcatagcg actttctttt
    14161 ctcgcagttc aaaatcaggc gtgtcgatgt agtaatttgt ttgaagaaca ggagtgacac
    14221 ctgtgaactg gtcttttaga cgattgtatt catctttttt caatagtgtt ttcaattcaa
    14281 tttctaaatg tttcattttt cttacctttt tttatcgttg aaagcggatt tatggtataa
    14341 taagcattgt atttattgta tatgaatctg gagaaaaaat caaagatatt tttgacggat
    14401 aatatgagaa caagggagaa tatatgacct tagaatggga agaatttcta gatccttaca
    14461 ttcaagctgt tggtgagtta aagattaaac ttcgtggtat tcgtaagcaa tatcgtaagc
    14521 aaaataagca ttctccaatt gagtttgtga ccggtcgagt caagccaatt gagagcatca
    14581 aagaaaaaat ggctcgtcgt ggcattactt atgcgacctt ggaacacgat ttgcaggata
    14641 ttgctggctt acgtgtgatg gttcagtttg tagatgacgt caaggaagta gtggatattt
    14701 tgcacaagcg tcaggatatg cgaatcatac aggagcgaga ttacattact catagaaaag
    14761 catcaggcta tcgttcctat catgtggtag tagaatatac ggttgatacc atcaatggag
    14821 ctaagactat tttggcagaa attcaaattc gtactttggc catgaatttc tgggcaacga
    14881 tagaacattc tctcaactac aagtaccaag gggatttccc agatgagatt aagaagcgac
    14941 tggaaattac agctagaatc gcccatcagt tggatgaaga aatgggtgaa attcgtgatg
    15001 atatccaaga agcccaggca ctttttgatc ctttgagtag aaaattaaat gacggtgtag
    15061 gaaacagtga cgatacagat gaagaataca ggtaaacgaa ttgatctgat agccaataga
    15121 aaaccgcaga gtcaaagggt tttgtatgaa ttgcgagatc gtttgaagag aaatcagttt
    15181 atactcaatg ataccaatcc ggatattgtc atttccattg gcggggatgg tatgctcttg
    15241 tcggcctttc ataagtacga aaatcagctt gagaaggtcc gctttatcgg tcttcacact
    15301 ggacatttgg gcttctatac agattatcgt gattttgagt tggacaagct agtgactaat
    15361 ttgcagctag atactggggc aagggtttct taccctgttc tgaatgtgaa ggtctttctt
    15421 gaaaatggtg aagttaagat tttcagagca ctcaacgaag ccagcatccg caggtctgat
    15481 cgaaccatgg tggcagatat tgtaataaat ggtgttccct ttgaacgttt tcgtggagac
    15541 gggctaacag tttcgacacc gactggtagt actgcctata acaagtctct tggcggtgct
    15601 gttttacacc ctaccattga agctttgcaa ttaacggaaa ttgccagcct taataatcgt
    15661 gtctatcgaa cactgggctc ttccattatt gtgcctaaga aggataagat tgaacttatt
    15721 ccaacaagaa acgattatca tactatttcg gttgacaata gcgtttattc tttccgtaat
    15781 attgagcgta ttgagtatca aatcgcccat cataagattc actttgtcgc gactcctagc
    15841 cataccagtt tctggaaccg tgttaaggat gcctttatcg gtgaggtgga tgaatgaggt
    15901 ttgaatttat cgcagatgaa catgtcaagg ttaagacctt cttaaaaaag cacgaggttt
    15961 ctaagggatt gctggccaag attaagtttc gaggtggagc tattctggtc aataatcaac
    16021 cgcaaaatgc aacgtatcta ttggacgttg gagactacgt taccattgac attcccgctg
    16081 agaaaggctt tgaaaccttg gaggctattg agcttccatt agatattctc tatgaggatg
    16141 accactttct agtcttgaat aaaccctatg gagtggcttc tattcctagt gttaatcact
    16201 ctaataccat tgccaatttt atcaagggtt actatgtcaa gcaaaattat gaaaatcagc
    16261 aggttcacat tgttaccaga ctagataggg acacttctgg cttgatgctc tttgccaagc
    16321 acggttatgc ccatgcacga ttagacaagc agttgcagaa gaaatctatc gagaaacgct
    16381 actttgcttt ggttaaggga gatggacatt tggagccaga aggggaaatt attgctccga
    16441 ttgcgcgtga tgaagattcc attattacca gacgagtggc taaaggcgga aagtatgccc
    16501 atacttcata caagattgta gcttcttatg gaaatattca cttggtctat attcacctgc
    16561 acactggtcg aacccatcaa atccgagtcc atttttctca tatcggtttt cctttgctgg
    16621 gagatgattt gtatggtggt agtctggaag atggtattca acgtcaggct ctgcattgcc
    16681 attacctatc cttttatcat ccatttttag agcaagactt gcagttagaa agtcccttgc
    16741 cggatgattt cagtaacctt attacccagt tatcaactaa tactctataa aaactgtctc
    16801 agagtataat tattatctta aaggagaaaa ctcatggaag tttttgaaag tctcaaagcc
    16861 aaccttgttg gtaaaaatgc tcgtatcgtt ctccctgaag gggaagagcc acgtattctt
    16921 caagcgacta aacgtttggt aaaagaaaca gaagtgattc ctgttttgtt aggaaatcct
    16981 gaaaaaatta aaatttatct tgaaattgaa gggatcatgg atggttatga ggtcatcgac
    17041 cctcaacatt atcctcaatt tgaagaaatg gtttctgcct tggtggagcg tcgcaagggc
    17101 aaaatgactg aagaagatgt acgcaaggtt ttggttgaag atgtcaacta ctttggtgtg
    17161 atgttggttt acttgggctt ggttgatgga atggtgtcag gagcgattca ctcaacagct
    17221 tcaacagttc gtccagctct acaaatcatc aaaactcgtc caaatgtaac tcgtacttca
    17281 ggagccttcc tcatggttcg tggtacggaa cgttacctat ttggagactg tgccattaac
    17341 atcaatccag atgcagaagc cttggctgaa attgccatca actcagcaat cacagctaag
    17401 atgtttggca tcgaacctaa aattgccatg ttgagctatt ctactaaagg ttcagggttt
    17461 ggtgaaagcg ttgataaggt cgttgaagca actaaaattg ctcacgactt gcgtcctgac
    17521 cttgaaatcg atggtgagtt gcaatttgat gcagcctttg ttcctgaaac tgcagctctg
    17581 aaagctcctg gaagtacggt agctggtcaa gcaaatgtct tcatcttccc aggtatcgag
    17641 gcaggaaata tcggttacaa gatggctgaa cgcctgggtg gctttgcggc tgtaggacct
    17701 gttttgcaag gtttaaacaa gccagttaat gatctttctc gtggatgtaa tgcagatgat
    17761 gtttacaagt tgaccctcat cacagcagct caagcagttc atcaatagtg aaaactataa
    17821 agcgatatac tatgctatac tgtagttatg aaactatgta cgaaaagcac tgccattaat
    17881 tcctgagaac taaattactg attggtgtca aaaaggaaaa cttccaagcg atgatatcct
    17941 gtctatacac gacctataga aatctgtaat atgtatgtcc gtaaaacgat aatttccctt
    18001 tttgatttta aatgagtatg aaaagagaat tttttcatga gaaaacgcat aatattaagt
    18061 gtcttgacac ctgctattat gcgttttcta caataaaata ggctccataa tatctatagt
    18121 ggatttaccc actacaaata ttatagagtc atttttgcac ctttcttagc ctttgttatc
    18181 gacaagcatt gttctagctc cttgttttta gaaaggtaat ttcccagcga aagcacccag
    18241 ttttttcttg gtagtttcat cgatttgttc aagagcagag ttgatggctt gaacggtcat
    18301 atcagaaaga gtctcaaggt cctctgggtc aacgacagct ggattgaaat caatgctgac
    18361 aactttctta tcgccagtta aggtcgcttg gacaagatct tgagcagatt tgccaacaaa
    18421 ttgcatagca gcaagttcag cttggctttg ttccatttgt ttttgaagtt tttgtgcttg
    18481 acgcatcatg ttttgcatgt tcatcataag atttctaaag ttcctttcat ctcaagggga
    18541 taatccttgt tgttaacaag tgcctgattt tctctcctaa ttgttattag tagcatagcc
    18601 atcaagccca agtattgatt ttattatacc atttttttaa gacatagtct tttattggtg
    18661 agagttattt atgtcaagga gtgattagaa ataaattaaa ataatgattt ttgctaagag
    18721 ggctctattc tagtttcatg
//
LOCUS       DAVLXH010000042        18709 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00028199
            SAMN33607166-rid17955573.denovo.042, whole genome shotgun sequence.
ACCESSION   DAVLXH010000042 DAVLXH010000000
VERSION     DAVLXH010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607166
            Sequence Read Archive: SRR23725544
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18709)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18709)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721421.1
            Genome Coverage       :: 115x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:42:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,210
            CDSs (total)                      :: 2,161
            Genes (coding)                    :: 2,023
            CDSs (with protein)               :: 2,023
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 73 of 138
            Pseudo Genes (incomplete)         :: 60 of 138
            Pseudo Genes (internal stop)      :: 40 of 138
            Pseudo Genes (multiple problems)  :: 31 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18709
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607166-rid17955573.denovo.042"
                     /strain="AUSMDU00028199"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1349"
     gene            complement(26..925)
                     /locus_tag="VYO11_001560"
     CDS             complement(26..925)
                     /locus_tag="VYO11_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000735961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HEV1596102.1"
                     /translation="MKKLPLVFSGCLLGLAGAGNLILDTLPVLSHLFSLTGLVLWIYF
                     LILHLFNWKETKQELTKPPLLSGMATFPMAGMILSTYVFRVFSYLPLVAQGIWWFSFL
                     LDLTLIAGFTIKFACPGRRVHATPSWTVLYVGIAVAALTYPLVGIIEIAYATLSFGFL
                     LTFYLYPLIYSDLKKHPLPLALLGQEGIYCAPFSLLLASLVRVGGTSLPTWVLIVMIL
                     ASQSFFFFVLTRLPNILKQGFQPAFSALTFPTIITATSLKMAQGILKLPFLDYLVLTE
                     TIICLTILFFVLGAYLIWLRKKV"
     gene            complement(1035..1583)
                     /locus_tag="VYO11_001561"
     CDS             complement(1035..1583)
                     /locus_tag="VYO11_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000206764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HEV1596103.1"
                     /translation="MTTFTIHTVESAPAEVKEILETVEKDNNGYIPNLIGLLANAPTV
                     LEAYQIVSSIHRRNSLTPVEREVVQITAAVTNGCAFCVAGHTAFSIKQIQMNDDLIQA
                     LRNRTPIETDPKLDTLAKFTLAVINTKGRVGDEALSEFLEAGYTQQNALDVVFGVSLA
                     ILCNYANNLANTPINPELQPYA"
     gene            complement(1801..3123)
                     /locus_tag="VYO11_001562"
     CDS             complement(1801..3123)
                     /locus_tag="VYO11_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:alanine symporter family protein"
                     /protein_id="HEV1596104.1"
                     /translation="MLELLKSIDDFAWGPPLLILLVGTGIYLTMRLGLLQVLRLPKAF
                     QLIFIQDKGHGDVSSFAALCTALASTVGTGNIIGVATAIKVGGPGALFWMWMAAFFGM
                     ATKYAEGLLAIKYRTKDDHGAVAGGPMHYILLGMGEKWRPLAVLFAVAGVLVALLGIG
                     TFTQVNSITESIQNTTTISPAITALVLSVFVAIAVFGGLKSISKVSTTVVPFMAIIYI
                     LGTLTVIFFNIGKIPGTIALVFTSAFSPLAAVGGFAGASVRMAIQNGVARGVFSNESG
                     LGSAPIAAAAAKTNEPVEQGLISMTGTFIDTLIICTLTGLTILVTGVWSGDLNGVALT
                     QSAFSTNFSHFGPALLTIFLVLFAFTTILGWNYYGERCFEFLFGVRFIWLYRVVFVLM
                     VLLGGFIELDMVWIIADIVNALMALPNLIALLVLSPVVIAETKKYFDK"
     regulatory      complement(3214..3302)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            complement(3466..5802)
                     /locus_tag="VYO11_001563"
     CDS             complement(3466..5802)
                     /locus_tag="VYO11_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HEV1596105.1"
                     /translation="MNKKILETLEFDKVKALFEPHLLTEQGLEQLRQLAPTAKADKIK
                     QAFAEMKEMQALFVEQPHFTILSTKEIAGVCKRLEMGADLNIEEFLLLKRVLLASREL
                     QSFYANLENVSLEELALWFEKLHDFPQLQGNLQAFNDAGFIENFASEELARIRRKIHD
                     SESQVRDVLQDLLKQKAQMLTEGIVASRNGRQVLPVKNTYRNKIAGVVHDISASGNTV
                     YIEPREVVKLSEEIASLRADERYEMLRILQEISERVRPHATEIANDAWIIGHLDLIRA
                     KVRFIQERQAVVPQLSENQEIQLLHVCHPLVKNAVANDVYFGQDLTAIVITGPNTGGK
                     TIMLKTLGLTQVMAQSGLPILADKGSCVGIFEEIFADIGDEQSIEQSLSTFSSHMTNI
                     VDILGKVNQHSLLLLDELGAGTDPQEGAALAMAILEDLRLRQIKTMATTHYPELKAYG
                     IETAFVQNASMEFDTATLRPTYRFMQGVPGRSNAFEIAKRLGLSEVIVGDASQQIDQD
                     NDVNRIIEQLEEQTLESRKRLDNIREVEQENLKMNRALKKLYNELNREKETELNKARE
                     QAAEIVDMALSESDQILKNLHSKSQLKPHEIIEAKAKLKKLAPEKVDLSKNKVLQKAK
                     KKRAPKVGDDIVVLSYGQRGTLTSQLKDGRWEAQVGLIKMTLEEKEFDLVQAQQEKPV
                     KKKQVNVVKRTSGRGPQARLDLRGKRYEEAMNELDTFIDQALLNNMAQVDIIHGIGTG
                     VIREGVTKYLQRNKHVKSFGYAPQNAGGSGATIVTFKG"
     gene            complement(5906..6454)
                     /locus_tag="VYO11_001564"
     CDS             complement(5906..6454)
                     /locus_tag="VYO11_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000622948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HEV1596106.1"
                     /translation="MISFLLLLILVWGFYIGYRRGLLLQVYYLISAMASAFMAGQFYK
                     GLGEQFHLLLPYANSQEGQGTFFFPSDQLFQLDKVFYAGIGYLLVFGIVYSIGRLLGL
                     LLHLIPSKKLGGKLFQVSAGILSMLVTLFVLQMALTILATIPMAVIQNPLEKSIVAKH
                     IIQSIPITTSWLKQIWVTNLIG"
     gene            complement(6451..6753)
                     /gene="zapA"
                     /locus_tag="VYO11_001565"
     CDS             complement(6451..6753)
                     /gene="zapA"
                     /locus_tag="VYO11_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HEV1596107.1"
                     /translation="MANLNRFKFTFGKKSLTLTSEHDNLFMEEIAKVATEKYQAIKEQ
                     MPSADDETIALLLAVNCLSTQLSREIEFDDKEQELEELRHKLVTCKQEQSKIEDSL"
     gene            6840..7721
                     /locus_tag="VYO11_001566"
     CDS             6840..7721
                     /locus_tag="VYO11_001566"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000146880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HEV1596108.1"
                     /translation="MASITLTPSEKDIQAFLEHYQTSLAPSKNPYIRYFLKLPQATVS
                     IYTSGKILLQGEGAEKYASFFGYQAVEQTSGQNLPLIGTDEVGNGSYFGGLAVVAAFV
                     TPDQHDFLRKLGVGDSKTLTDQKIRQIAPILKEKIQHQALLLSPSKYNEVIGDRYNAV
                     SVKVALHNQAIYLLLQKGVQPEKIVIDAFTSAKNYDKYLAQEANRFSNPISLEEKAEG
                     KYLSVAVSSVIARDLFLENLENLGRELGYQLPSGAGTASDKVASQILQAYGMQGLNFC
                     AKLHFKNTEKAKKRLER"
     gene            7725..8339
                     /gene="lepB"
                     /locus_tag="VYO11_001567"
     CDS             7725..8339
                     /gene="lepB"
                     /locus_tag="VYO11_001567"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HEV1596109.1"
                     /translation="MNSFKNFLKEWGLFLLILSLLALSRIFFWSNVRVEGHSMDPTLA
                     DGEILFVVKHLPIDRFDIVVAHEEDGNKDIVKRVIGMPGDTIRYENDKLYINDKETDE
                     PYLADYIKRFKDDKLQNTYSGKGFEGNKGTFFRSIAQKAQAFTVDVNYNTNFSFTVPE
                     GEYLLLGDDRLVSSDSRHVGTFKAKDITGEAKFRFWPITRIGTF"
     gene            8419..8541
                     /locus_tag="VYO11_001568"
     CDS             8419..8541
                     /locus_tag="VYO11_001568"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="chlorohydrolase"
                     /protein_id="HEV1596110.1"
                     /translation="MKIKEQTRKLAVGCLKQCFEVVDRTDEVSSKYCFEVADGS"
     gene            8618..10984
                     /locus_tag="VYO11_001569"
     CDS             8618..10984
                     /locus_tag="VYO11_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HEV1596111.1"
                     /translation="MEVYFSGTIERIIFENPSNFYRILLLEIDDTDAEDFDDFEIIVT
                     GTMADVIEGEDYIFWGQIVQHSKYGEQLQISRYDRAKPTSKGLVKYFSSSHFKGIGLK
                     TAQKIVDTYGENTIDEILQHPEKLEGIAGLSAKNREAFVSTLRLNYGTEMVLAKLANY
                     GIPNKLAFQIQDFYKEETLDVVENYPYQLVEDIKGLGFTIADQLAEELGIESQAPERF
                     RAGLVHSLFQACMETGDTYVEARDLLEQTLTLLESSRPVELDPSQVAQELSYLIEEDK
                     VQQIDTKIFDNSLFFAEEGIRSHLIRILEKGKQKSQDLETIQKHITTVEQELGIEYDN
                     IQKQAICDAIQNKVFILTGGPGTGKTTVINGIIAVYALLEGLDFRKKSNLPILLAAPT
                     GRAARRMNELTGLPSATIHRHLGMTGDDDTSHLEDYLDADFIIVDEFSMVDTWLANQL
                     FSNISSNSKILIVGDSDQLPSVSPGQVLADLLHIPLIPQTRLEKIYRQSEESTIVTLA
                     SQIRQGILPADFTQKKADRSYFEIASGHIPATIEKILDAALRNGIPARDIQVLAPMYR
                     GTAGIDAINQLMQDLLNPPQKDQLSFEAPQCHYRKGDKVIHLVNDAEINVFNGDLGAI
                     TDLIPGKYTESKQDEIVIDFDGNEVSYPRNEWYKIRLAYAMSIHKSQGSEFPVVILPI
                     TSASRRMLERNLIYTAITRAKSKLILLGELQAFDYATQHIGTARKTYLIERFSDLLEN
                     VEEKQQAVSETVTSSASEQSYILTEENWDSIPAMIGITDTDLKEIFGK"
     gene            complement(11032..12315)
                     /locus_tag="VYO11_001570"
     CDS             complement(11032..12315)
                     /locus_tag="VYO11_001570"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HEV1596112.1"
                     /translation="MSVSFENKETNRGVLTFTISQDQIKPELDRVFKSVKKSLNVPGF
                     RKGHLPRPIFDKKFGEESLYQDVMNALLPNAYEAAVKEAGLEVVAQPKIDVTSMEKGQ
                     DWVIAAEVVTKPEVKLGDYKNLEVSVDVEKEVTDADVEERIERERNNLAELVIKEAAA
                     ENGDTVVIDFVGSIDGVEFDGGKGENFSLGLGSGQFIPGFEDQLVGHSAGETVDVIVT
                     FPEDYQAEDLAGKEAKFVTTIHEVKAKEVPALDDELAKDIDEEVETLADLKEKYRKEL
                     AAAKEEAYKDAVEGAAIDTAVENAEIVELPEEMIHEEVHRSVNEFLGNLQRQGINPDM
                     YFQITGTTQEDLHNQYQAEAESRTKTNLVIEAVAKAEGFDASEEEIQKEVEQLAADYN
                     MEVAQVQNLLSADMLKHDITIKKAVELITSTATVK"
     gene            complement(13110..14246)
                     /locus_tag="VYO11_001571"
     CDS             complement(13110..14246)
                     /locus_tag="VYO11_001571"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HEV1596113.1"
                     /translation="MKHSVHFGAGNIGRGFIGEILFKNGFHIDFVDVNNQIIHALNEK
                     GKYEIEIAQKGQSRIEVTNVAGINSKEHPEQVIEAIQKTDIITTAIGPNILPFIAELL
                     AKGIEARRVAGNTQALDVMACENMIGGSQFLYQEVKKYLSPEGLTFADNYIGFPNAAV
                     DRIVPAQSHEDSLFVVVEPFNEWVVETKRLKNPDLRLKDVHYEEDLEPFIERKLFSVN
                     SGHATSAYIGAHYGAKTILEALQNPNIKSRIESVLAEIRSLLIAKWNFDKKELENYHK
                     VIIERFENPFIVDEVSRVARTPIRKLGYNERFIRPIRELKELSLSYKNLLKTVGYAFD
                     YRDVNDEESMRLGELLAKQSVKDVVIQVTGLDDQELIEQIVEYI"
     gene            complement(14308..14745)
                     /locus_tag="VYO11_001572"
     CDS             complement(14308..14745)
                     /locus_tag="VYO11_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV1596114.1"
                     /translation="MKLEKHLIKLNKQFSNKEEAICYCGQVLYEGGYVNEDYIEAMIE
                     RDKELSVYMGNFIAIPHGTDAAKNDVLKSGITVVQVPRGVDFGNVSNPQVATVLFGIA
                     GIGNEHLEIIQKISIFCADVDNVLKLADAQSKEEVLRLFDAVE"
     gene            complement(14747..16702)
                     /locus_tag="VYO11_001573"
     CDS             complement(14747..16702)
                     /locus_tag="VYO11_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HEV1596115.1"
                     /translation="MLLTKREEQLLKAFLHVGKLSMQDMTEILQVSSRTIYRTLSDLT
                     DSMEQYGIEITKHGKYYILTGELDDLPTELEVLVEYSPQERQELITYRLLTESGFVTN
                     EALQECTKVSNVTIIQDISDIDKRLLDFDLKIERQKGYRISGDSVGKRRFLAILLTNC
                     ISVADFSTGNFGSFDILEADRTRLASQIVNKQLSGFPDMDARMKMFFAILLSLIGQEQ
                     NIENSPNTSKQALEISQKIFQTYSKQTAQFYSIQEIIYFASILDELIIKRQDNPLFTE
                     KFDGEFFYNISNLIDTVSMYTKIDFFKDKVLFNFLFHHIRLSLGVPILFQGENLPESV
                     QILVERNKFLYTVISLLVNDIFPKYLHTEYEYGMIALHFISSLGRSPEIYPVRVLLLT
                     DERRVTRDLLVSKIKSVAPFVELIDIQSLVDYHSIDLSQYDYILSTKPLTNQEIGVIS
                     SFPTVKELLELQERLQYVQAHRTIVARDAIAPEKSYDLQDYLISSSQLLSQFELVQLE
                     NNQSFEHTVEQIIQYQKNVSDRDYLTRKLLSHFQNSPMAIPNTGLVLLHSQSSKVTTN
                     SFTMFELKLPISALSMKREEEEVKRCLLMLMSKEASEEARDLMTAISQSIIENHLYTE
                     IYKTGNQSIIYQMLNTIFNEKIKKLEN"
     gene            complement(16726..18495)
                     /locus_tag="VYO11_001574"
     CDS             complement(16726..18495)
                     /locus_tag="VYO11_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000391672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICBA"
                     /protein_id="HEV1596116.1"
                     /translation="MEEKVSLKVRVQKLGTSLSNMVMPNIGAFIAWGVLTALFIADGY
                     LPNEQLATVVGPMLTYLLPILIGYTGGYMIHGQRGAVVGAIATVGAITGSSVPMFIGA
                     MVMGPLGGWTIKKFDEKFQEKIRPGFEMLVNNFSAGLVGFALLLLAFYAIGPVVSTLT
                     GAVGNGVEAIVNARLLPMANIIIEPAKVLFLNNALNHGIFTPLGVEQVAQAGKSILFL
                     LEANPGPGLGILLAYAVFGKGSAKSSSWGAMVIHFFGGIHEIYFPYVMMKPTLFLAAM
                     AGGISGTFTFQLLDAGLKSPASPGSIIAIMATAPKGVWPHLNVLLGVLVAAVVSFLVA
                     ALILHADKSTEDSLEAAQAATQAAKAQSKGQLVSTSVDAVVSTDSVEKIIFACDAGMG
                     SSAMGASILRDKVKKAGLEIPVSNQAISNLLDTPKTLIVTQEELTPRAKDKSPSAIHV
                     SVDNFLASPRYDEIVASLTGAFPIAEIEGDIPTSAPVDSQEIDLNHIDAVVVAYGKAQ
                     GTATMGCETIRAIFRNKNIRIPVSTAKISELGEFNSKNIMIVTTISLQAEVQQAAPNS
                     QFLIVDSLVTTPEYDKMAARMYK"
BASE COUNT         5655 a         4021 c         3587 g         5446 t
ORIGIN      
        1 aaaaataagg tttagctatt tctagctaga ccttttttcg taaccaaatc agataagcac
       61 ctagtacaaa gaataaaata gttaggcata taatggtttc agtcaatacc aggtaatcca
      121 gaaatggaag tttcaaaatt ccctgagcca tcttgagcga ggtcgctgtg ataatggttg
      181 ggaaggtgag ggctgagaag gctggttgaa aaccttgttt taaaatgttg ggcagacgag
      241 ttaaaacaaa gaaaaagaag gattgagaag ccaaaatcat gacaatcaag acccaagtcg
      301 gcaggctggt tcctcctact cgaactagag aagccaagag tagagagaaa ggagcacagt
      361 agattccttc ttgtccaagc aaggctagtg ggagtggatg tttctttaaa tcgctataaa
      421 taaggggata gagatagaag gtcaagagaa aaccaaaact caaggtcgca taggcaattt
      481 cgataatacc taccagagga taggtcaagg cagccactgc tatccccaca tagagaaccg
      541 tccaacttgg agtggcatga accctccgcc ctggacaagc aaacttgatg gtaaaaccag
      601 caatcaaggt caaatccaag agaaatgaaa accaccaaat cccttgtgct accaaaggaa
      661 gataagagaa tacgcgaaag acataggtcg ataaaatcat cccagccata ggaaaggttg
      721 ccattcctga caaaagaggg ggcttggtca attcttgctt ggtttctttc caattaaaga
      781 gatgcagaat tagaaagtaa atccataaaa ccaaaccagt cagactaaaa agatgggata
      841 gaaccggcaa cgtatctaaa ataagatttc cagctcctgc caaacctagc aaacaacctg
      901 aaaatactaa ggggagtttt ttcatcctaa cctccaataa tcatattagt ttcagtataa
      961 cataaaagcg cttaaatgag gatttaaaaa aacgaagtcc gcttatttca gacttcattt
     1021 tactcagata tgaattaggc ataaggttgc aattctggat taattggtgt attagctaag
     1081 ttgttggcat agttacagag gattgctagg ctgacaccaa aaaccacatc caaggcattt
     1141 tgttgagtgt agccagcttc taaaaactca gacaaggctt catctcctac acgacccttg
     1201 gtattgataa ctgccaaggt aaacttagct agggtatcca atttaggatc tgtttcaatt
     1261 ggagtacgat tgcgaagagc ttgaatcaag tcatcattca tctggatttg tttgatggaa
     1321 aaggctgtgt gacctgcgac acagaaggca caaccattgg tcacggctgc cgtgatttgc
     1381 accacttcac gctcaacggg tgtcaggctg ttgcgacggt ggatagatga gacaatttgg
     1441 taggcttcta aaacagtcgg ggcattggcc aagagaccga ttaggttggg aatatagcca
     1501 ttgttgtctt tttctactgt ttcaagaatt tctttcactt ctgctggtgc tgactctact
     1561 gtatggatag taaatgttgt cataagatac ctcttttctt attattgaca ctaatattat
     1621 tggaaaatct tataaaatcc tgattcctaa gtttatctaa gataaagctt tattctctca
     1681 taagattttc gttgttatat tagtttatca cacttccaat cacttgcata atatatatta
     1741 tatatcaggc tgataaaaat tatttatagg caaaaaaatc acacgagctg tgtgattcca
     1801 ttatttgtca aaatactttt tagtttcagc aataacgact ggcgacaaga ccaagagggc
     1861 aatcaagttt ggcagagcca tcaaggcgtt aacgatatct gcgataatcc agaccatatc
     1921 caactcgata aatcctccta acaagaccat gagcacaaaa accacacggt agagccagat
     1981 aaagcgaacc ccaaagagga actcaaaaca gcgttctccg taatagttcc aacctagaat
     2041 cgttgtaaag gcaaaaagta caaggaagat ggtcaagaga gcaggcccaa agtgtgaaaa
     2101 gtttgttgag aaagctgact gagtcaaggc aaccccattc aagtcaccgc tccaaactcc
     2161 agttaccaag atggtcaaac cagttagagt acaaatgatg agggtatcaa taaaggttcc
     2221 tgtcatggaa atcaaacctt gctctactgg ttcatttgtc ttggcagctg cagctgcaat
     2281 aggagcagaa cccagaccag attcgtttga gaacacacca cgcgccacac cattttgaat
     2341 agccatccga acgctagcac cagcaaatcc acctaccgca gcaaggggac taaaagctga
     2401 ggtaaagact aaagcgattg tgccagggat ttttccgata ttaaagaaaa taactgtaag
     2461 agttcctaag atataaatga tggccataaa aggaacaaca gtagttgaaa ccttagaaat
     2521 agacttaagt ccaccaaaga ctgcaatcgc tacaaagaca gacaagacga gagctgtgat
     2581 ggctggcgaa atcgtcgttg tattttggat agattctgta atcgagttga cttgggtgaa
     2641 ggttccgatt cccaagagag caaccaatac tcctgctact gcaaacaaaa cagcaagtgg
     2701 tcgccacttt tctcccatcc ctagaaggat atagtgcatg ggacctcccg ctactgcacc
     2761 atggtcgtcc ttggtgcggt atttgatggc caagagtcct tccgcatact tggtagccat
     2821 tccaaagaaa gccgccatcc acatccaaaa tagagctcct ggtccaccaa ccttgatagc
     2881 cgtcgcaact cctatgatat ttcctgttcc aacagttgat gccaaggctg tacacagagc
     2941 tgcaaaactg gatacatcac catgtccctt atcctggata aaaataagct gaaaggcctt
     3001 gggcagacgc aaaacctgca agagtcctag ccgcatggtt aggtaaatcc ctgttccgac
     3061 caataaaatc aagaggggcg gtccccaagc aaaatcatcg attgatttaa gcaattctaa
     3121 catttccttc tcctatcgtt tcaaccccaa aagaaagagc acatgcaaga tacatgtact
     3181 ctggaatgct tagataaatg ctaaaaagcg gtctatccta gctctgtcct tttacctgag
     3241 agtttgagca gttgcctgcc ttgccccttc ggtgccttta cggtctctcc agagttccgt
     3301 ccatttacag tcatggaaaa tcaaacgatt ccccacttct attaaacttc attcggtgtt
     3361 ggtatttaat tgattctaat tttacaaaaa atgttggctt ttgtcaatgt gtttattagt
     3421 aaaaattagt tcaacagttt ttactttata aagtccagaa tactgctatc ctttaaaagt
     3481 gacaatagtc gcaccactgc ctccagcatt ttgtggggca tagccgaaac tcttgacatg
     3541 tttgtttctt tgcaagtatt tggtaactcc ttcacggatg actcctgttc cgataccatg
     3601 gatgatatca acttgagcca tattgttaag caaggcttgg tcgatgaagg tatctagctc
     3661 attcatggct tcttcatagc gcttgcctcg aagatccagt ctagcttgag gtcctcgccc
     3721 agaagttcgt ttcacaacat tgacctgttt cttcttgact ggtttttctt gctgggcttg
     3781 aacaagatca aactctttct cttccaaggt catcttaatc aagccaactt gggcttccca
     3841 gcggccgtcc ttgagttgac tggtcaaggt accacgctga ccataactga gaaccacgat
     3901 atcatctccc acctttggag ctcgtttttt cttggccttt tgaaggacct tgtttttaga
     3961 caagtccact ttttcaggag ccaatttttt caacttggcc ttggcttcaa tgatttcgtg
     4021 gggcttgagt tgggatttac tgtggagatt tttgagaatc tggtcacttt cacttagggc
     4081 catatccaca atctcagcag cctgttcacg cgccttgtta agctcggttt ccttttcacg
     4141 attaagctcg ttgtagagtt tttttagcgc acggttcatc ttgagatttt cttgctccac
     4201 ctcacggata ttgtccaaac gtttgcggct ttccagcgtc tgctcttcta attgctcaat
     4261 gatacgattg acgtcattgt cctgatcgat ctgctgactg gcatctccta cgataacttc
     4321 agataggcct agacgtttgg caatttcaaa ggcattactt cggccaggaa caccctgcat
     4381 aaagcgatag gttgggcgaa gagttgcagt atcaaactcc atactggcat tttgcacaaa
     4441 ggctgtctca ataccgtagg ccttgagttc tggatagtgg gtcgtcgcca tggtcttgat
     4501 ttgacgcagg cgaaggtcct ccagaatagc catggcaagg gctgctccct cttggggatc
     4561 agtaccagcc cccaactcat ccaaaagtaa gagtgaatgt tggttgacct tgccaagaat
     4621 atccacgata ttggtcatat ggctagagaa ggtagacaag ctctgctcaa tagactgctc
     4681 atctccaata tcagcaaaaa tttcttcaaa aataccaaca caacttccct tgtctgctaa
     4741 aatcggtaat cctgactggg ccatgacctg tgtcaagccc agagttttga gcatgatggt
     4801 cttcccacct gtattgggac ctgtaatgac aatagctgtt aaatcttgac caaaatagac
     4861 atcatttgcg acggcatttt tgaccaaagg atggcagaca tggagcagtt gaatctcttg
     4921 attttctgac agctgaggca cgactgcttg tctttcttgg ataaatcgaa cctttgcacg
     4981 aatcaagtcc agatgaccga taatccaagc gtcattagca atctcagtcg catgagggcg
     5041 gacacgctca gaaatttctt ggagaatgcg aagcatttca tagcgctcat ctgctcgcag
     5101 actggcaatt tcttcgctca gtttgactac ctcacgtggt tcgatataga cggtgtttcc
     5161 actagcagaa atatcatgaa cgacacctgc aatcttattg cggtaggtgt ttttgactgg
     5221 taaaacctga cggccatttc tgctagcaac aattccttcc gtcaacatct gcgctttttg
     5281 cttgagtaag tcttgtaaaa catcgcgtac ctgactctcg ctatcatgta tttttcgacg
     5341 gattcgcgcc aattcttcac tggcaaaatt ttcaatgaaa cccgcatcat taaaggcctg
     5401 aagatttcct tgtaattgcg gaaaatcatg taatttctca aaccaaaggg ctaattcttc
     5461 caagctgaca ttttccagat tggcataaaa actttgaagt tctcggctgg caagaagcac
     5521 gcgtttcaag agtaggaact cctcgatatt gagatccgct cccatctcca acctcttgca
     5581 gactcctgca atttccttag ttgagagaat agtaaaatgc ggttgctcga cgaaaagagc
     5641 ctgcatttct ttcatctcag caaaagcctg tttgatttta tctgctttgg cagtcggagc
     5701 cagctgtctc aattgctcca agccctgctc ggtcaacaaa tgaggctcaa acaaggcctt
     5761 gaccttatcg aactctaatg tttctaatat tttcttattc atctttattt ccttgtcttt
     5821 gaatgtctag gtgtggtagc tttttacatt ctgatagatt cgagtcaaat ctgtaaacaa
     5881 agggctagga aaactcctgc cctttttatc cgattaaatt tgtcacccag atttgtttga
     5941 gccaactggt tgttatcggt atgctctgga tgatgtgttt tgcgacgata ctcttttcaa
     6001 gaggattttg tataactgcc atggggatgg tcgccaagat tgtcaaggcc atttgcaaga
     6061 caaataaggt caccaacatg gacaagatac ctgctgaaac ttggaacaac ttaccaccca
     6121 gttttttgct aggaatcaag tgtaagagaa gaccaagcaa acgaccaatg ctatagacaa
     6181 tcccaaatac aagcaagtag ccgatacctg cataaaagac cttatccagc tgaaagagtt
     6241 gatccgatgg gaaaaagaaa gtcccctgac cttcctgcga atttgcataa gggagcaata
     6301 aatggaattg ctctccaagc cccttataaa actggccagc cataaaagcc gatgccatgg
     6361 ctgaaatcag gtaataaacc tgtaagagca ggcctctccg atagccgata taaaatcccc
     6421 aaaccaagat caatagaaga aggaatgaaa tcataaggaa tcctcaatct tgctctgttc
     6481 ttgcttacaa gtcacaagct tgtgacggag ttcttctagc tcttgctcct tatcgtcaaa
     6541 ttcaatctca cggctgagct gagttgataa acagttgact gccaacaaaa gagcgattgt
     6601 ttcatcatct gcgctaggca tttgttcttt aattgcttgg tatttttctg tcgcaacctt
     6661 agcgatttcc tccataaaaa ggttatcatg ttcgcttgtc aaggttaacg attttttccc
     6721 gaatgtaaat ttgaatcgat ttagatttgc cataaaattc acctcacgat attataccaa
     6781 aattcgctaa ttttgtcagt ttttacaaat tttactgctt ttgtggtaca atagaaacta
     6841 tggcaagtat cacactcaca ccaagcgaaa aggatattca ggcttttctt gaacactatc
     6901 aaaccagtct ggctcctagc aagaatccct atatccgcta ctttttgaaa ctacctcaag
     6961 caacggtttc tatctatact tctggaaaaa tcttgcttca gggtgaaggg gctgaaaaat
     7021 acgccagttt ctttggctat caagctgtag agcaaaccag cggacaaaat cttcctttaa
     7081 ttgggacaga tgaggtggga aatggttcct actttggtgg gcttgcagtt gtggctgcct
     7141 ttgtcacacc tgaccagcac gactttttac gaaaactcgg tgtgggagat tctaagactc
     7201 tgaccgacca aaagattcgt cagattgctc ctattctcaa ggaaaaaatc cagcaccagg
     7261 cactccttct ctcacccagc aagtacaacg aggtcatcgg agaccgctac aatgctgttt
     7321 cggttaaggt tgccctccat aatcaggcta tctatctcct ccttcaaaaa ggtgttcagc
     7381 ctgagaaaat tgtgattgat gcctttacca gtgctaaaaa ttatgacaag tacttggcac
     7441 aagaggccaa tcgtttcagc aatcctatca gcttagaaga aaaggctgag ggcaaatact
     7501 tgtctgtcgc agtttcttct gtcattgcgc gtgatctctt tctggaaaat cttgaaaatc
     7561 tgggacgaga actgggttat cagcttccaa gtggagctgg aacggcttct gacaaggtgg
     7621 ctagccagat tttgcaagcc tatggtatgc agggactcaa cttctgcgcc aaattgcact
     7681 ttaaaaacac tgaaaaagcg aaaaaacgct tagaaaggta agttatgaat tcatttaaaa
     7741 atttcttaaa agagtgggga ctgttcctcc taattctgtc attactagct ttaagtcgta
     7801 tctttttttg gagcaatgtt cgcgtagaag gacattccat ggatccgacc ctagcggatg
     7861 gcgaaattct cttcgttgta aaacaccttc ctattgaccg ttttgatatc gtggtggccc
     7921 atgaggaaga tggcaataag gacatcgtca agcgcgtgat tggaatgcct ggcgacacca
     7981 ttcgttacga aaatgataaa ctctacatca atgacaaaga aacggacgag ccttatctag
     8041 cagactatat caaacgcttc aaggatgaca aactccaaaa cacttactca ggcaagggct
     8101 ttgaaggaaa taaaggaact ttctttagaa gtatcgctca aaaagcccaa gccttcacag
     8161 ttgatgtcaa ctacaacacc aactttagct ttactgttcc agaaggagaa taccttctcc
     8221 tcggagatga ccgcttggtt tcgagcgaca gccgccacgt aggtaccttc aaagcaaaag
     8281 atatcacagg ggaagctaaa ttccgcttct ggccaatcac ccgtatcgga acattttaag
     8341 agacctaaga ggccgagaat cacaaatctc agcctcttct tctatcgtga gaagtgattg
     8401 tttattgaca aatactcaat gaaaatcaaa gaacaaacta ggaagctagc cgtaggctgc
     8461 ttaaaacagt gttttgaggt tgtggataga actgacgaag tcagctcaaa atactgtttt
     8521 gaggttgcag atggaagctg acgtggtttg aagatatttt cgaagagtat aaaataaaaa
     8581 caatcccaac tctcacctat tcatgcaaag gaattttatg gaagtttatt tttcaggaac
     8641 cattgaacgg attatttttg aaaatcccag caatttttat cgcatcctcc tcctagaaat
     8701 cgacgatacg gacgcagagg attttgatga ttttgaaatc attgtcacag gaaccatggc
     8761 tgatgtaatt gagggcgaag actatatttt ttgggggcaa attgtccagc actccaagta
     8821 tggagaacaa ctgcaaatca gtcgttatga tcgcgcaaaa ccaactagta agggattggt
     8881 caagtacttt tcaagtagcc atttcaaggg gattggtctc aagacagctc agaaaatcgt
     8941 agatacctat ggcgaaaata ccattgatga aattttgcaa cacccagaaa agttagaagg
     9001 catcgcagga ctctctgcca aaaatcgcga ggctttcgtc tccactctcc gtctcaacta
     9061 cggaacggag atggttttgg ccaaactagc caactacggc attcccaaca aactagcctt
     9121 tcagattcaa gacttttaca aggaagaaac ccttgatgtg gttgaaaatt atccctacca
     9181 gctggttgag gatatcaagg gtttgggctt taccattgct gaccaactag ctgaggaact
     9241 aggcatcgaa agtcaggctc ctgaacgctt ccgcgccggt ctagttcaca gtctttttca
     9301 ggcctgtatg gaaacagggg acacctatgt tgaagcacgg gatttgctgg aacaaaccct
     9361 tactctcctt gagtcttccc gtcccgtgga actagacccc agccaagttg cccaagagct
     9421 ctcctacctg atcgaagaag acaaggttca gcagattgat accaagatct ttgacaacag
     9481 cctctttttc gctgaggaag gtatccgcag tcacttgatt cgtatccttg aaaaaggaaa
     9541 acagaagagc caagatttag aaactattca aaagcatatc actactgtcg agcaagaact
     9601 ggggattgag tatgataaca ttcaaaaaca agctatttgt gacgctatcc agaacaaggt
     9661 ctttatcctg acaggtgggc ctggtactgg taagacaact gttatcaatg gaatcatcgc
     9721 tgtttatgcc cttttagaag gacttgactt caggaagaaa agcaatctgc ccattcttct
     9781 tgctgctcca actggtcgag ctgctcgtcg catgaatgaa ttgacaggtt tgcctagcgc
     9841 gaccatacat cgccacttgg gaatgacagg tgacgatgat accagtcatc tggaagatta
     9901 cctagatgct gactttatca tcgtggatga attctctatg gtggatactt ggctggccaa
     9961 tcaactcttc tccaatatct cttctaacag taagatcctc atcgtgggtg acagtgatca
    10021 gctaccttct gtcagtcctg gacaggttct agcggatctg cttcatattc ctttgattcc
    10081 tcagactcgc ttggaaaaaa tttatcgaca aagcgaagaa tcaaccatcg tcaccctagc
    10141 tagtcagatt cgacagggca tcttgccagc tgatttcacc caaaaaaaag ctgaccgttc
    10201 ctactttgaa attgctagtg gccatattcc tgccactatt gaaaaaatct tagatgccgc
    10261 cctcagaaat ggtattcctg cccgtgatat ccaagttctg gctcctatgt accgagggac
    10321 ggcagggatt gatgctatca atcagctcat gcaagacctg ctcaatcccc cacaaaaaga
    10381 tcaactcagt tttgaagctc ctcagtgcca ctatcgtaag ggagacaagg tcattcattt
    10441 ggttaacgat gctgaaatca atgtctttaa tggggattta ggagctatca cagacctgat
    10501 tcctggtaaa tacaccgaat cgaaacaaga cgagattgtc attgattttg atggtaatga
    10561 agtctcttac ccccgtaacg aatggtacaa gattcgcttg gcctatgcca tgagtattca
    10621 taagtctcag ggaagtgagt tcccagttgt catcctaccg attactagtg ctagccgacg
    10681 tatgctggag cgaaatctca tctacacagc cattacacgt gccaaaagca aactcatctt
    10741 actaggcgaa ttacaagcct tcgactatgc tacccaacac atcggaactg cccgaaaaac
    10801 ctatctgatt gaacgcttca gtgatctact ggagaatgtt gaagaaaagc aacaagctgt
    10861 ctctgaaaca gtcacatcaa gtgcctctga acaatcctac atcctaaccg aagaaaactg
    10921 ggacagcatt ccagccatga ttgggattac agacacagac ctcaaagaga tttttggaaa
    10981 atagtacatc agaaaaccca ccaattcagg tgggttttct gtttattaag attattttac
    11041 tgttgctgtg cttgtgatca attcaacagc ttttttgata gtgatatcat gtttcaacat
    11101 gtcagctgaa agcaagtttt gaacttgtgc aacttccatg ttgtagtctg ctgccaattg
    11161 ctcaacttct ttttggattt cttcttctga agcatcaaat ccttcagctt tggcaactgc
    11221 ttcgataaca aggttagtct tagtacgtga ctcagcttct gcttggtatt ggttgtgaag
    11281 gtcttcttga gtagttccag tgatttggaa gtacatgtca gggttgatcc cttgacgttg
    11341 caagttccca aggaattcat ttactgaacg gtgaacttct tcatggatca tttcttctgg
    11401 aagttctacg atttcagcgt tttctacagc tgtatcaatt gctgcacctt caactgcatc
    11461 tttgtaagct tcttctttag cagcagccaa ttctttgcgg tatttttctt tcaagtcagc
    11521 aagtgtttca acttcttcat caatgtcttt tgcaagttca tcgtcaagag ctggaacttc
    11581 tttagctttt acttcgtgga tagttgtcac gaatttagct tctttacctg caaggtcttc
    11641 tgcttggtag tcttctggga atgttacgat aacatcaacg gtttcgccag ctgagtgacc
    11701 taccaattgg tcttcgaaac cagggatgaa ttgacctgaa ccaagtccaa gtgagaagtt
    11761 ttcacctttt ccaccgtcaa attcaacacc gtcgatagaa ccaacgaagt cgatcacaac
    11821 agtgtcgccg ttttcagcag cagcttcctt gataaccaat tcagccaggt tgttgcgttc
    11881 gcgttcgata cgctcttcaa catcagcgtc agttacttct ttttctacat caactgatac
    11941 ttcaaggttt ttgtagtcac ccaattttac ttcaggtttt gtaacgactt cagcagcgat
    12001 aacccagtct tgaccttttt ccattgaagt tacgtcaatt tttggttggg caaccacttc
    12061 aagaccagct tcttttacag ctgcttcata agcgtttggc aaaagagcgt tcataacgtc
    12121 ttggtaaagt gattcttcac caaatttttt atcgaagata ggacgtggaa ggtgaccttt
    12181 acggaaacct ggaacattaa gagatttctt cactgacttg aagacacggt ccaattctgg
    12241 tttgatttgg tcttgagaga tagtgaaagt caagacacca cggtttgttt ctttgttttc
    12301 aaatgataca gacattctgt catttctcct taaaattttt taaatacagt ctattataac
    12361 attttctata aataaaatct agactaatgc agacaattat agacaacaag cctttttcct
    12421 aactaaaaca ctcataaagt atagacaatt ttagactact ttggatatct tttggttagt
    12481 cattttccaa aactaattta tctaatttat ctaatttttc agttatatag tagattgaaa
    12541 ctagaatagt acacttctac ttctaaaaca tttttagaaa tcgatttgac tgtcctgatc
    12601 gatttgtcct gttcttgttt cattttacta tatagatcgc attcgaaaga attcgttcca
    12661 aaattgcttg gttcgttctt ctcttggacg actaaagaat tgatgggcat tatttttttc
    12721 aacaattttc ccactgtcca taaaaataac atgatgggct acatctctag caaaacctat
    12781 ctcataaagc tgatcaaaaa ctcaatctga gaagaaaatc caataaggct ttccataata
    12841 aaggacatcc tatcaagatt tttgaacacc cgataggctg cctttttccg attttgaaga
    12901 ctttttgtct agcttctttt accttataaa taacaacaaa aatcaaagac aagctagaaa
    12961 gattaccgca gataactcaa acagtgtttt gaggttgcag ataagactga cggagtcagc
    13021 tcaaagcact gctttgaggt tgtagataga acaacatatg cctaagacaa agcgatgcta
    13081 acctgatttg aagagatttt caaaaaagat taaatatact ctacaatttg ctcaatcaat
    13141 tcttggtcgt ctaaacctgt aacttgtata acaacatctt tgactgattg tttagccaac
    13201 aattcaccta atcgcatact ttcttcatca tttacatcgc gatagtcaaa ggcatagcca
    13261 actgttttaa gtaggttttt atatgacaaa ctgagttctt tcaattcacg tatcggccgg
    13321 atgaatcgtt cattatagcc taattttcgg attggagtac gagctacgcg actaacctcg
    13381 tccactatga aagggttttc aaaccgttct ataatgactt tgtgataatt ctccaattct
    13441 tttttatcaa agttccattt ggcaatcaag agactccgaa tttcagctaa tacagattca
    13501 atccgagatt taatattagg attttgaaga gcttccaaaa ttgtcttggc accataatgc
    13561 gcaccaatgt aagctgaagt tgcatgtcca gaattgactg aaaaaagttt tcgctcaata
    13621 aagggttcta aatcttcttc ataatgcaca tcttttagac gtaaatctgg atttttaaga
    13681 cgcttggttt ccacgaccca ttcattaaag ggctcgacca caacaaaaag ggaatcttcg
    13741 tgactttgtg ctggaacaat cctgtctact gcagcatttg gaaaacctat gtagttatca
    13801 gcaaatgtca aaccttccgg acttaaatat ttcttgactt cttgataaag aaattgagac
    13861 ccgccaatca tattttcaca ggccataaca tccaatgcct gtgtatttcc tgcaactcgg
    13921 cgagcttcga ttcctttggc tagaagttcg gcgataaaag ggagtatatt aggtccgatt
    13981 gcagtagtaa taatatccgt cttttgaatc gcttcaatga cttgctcagg atgttctttg
    14041 ctattaatgc cagccacatt agttacttct atacgagact gtcctttctg tgcaatttca
    14101 atttcatact tgcccttttc atttagagca tgaattatct gattattgac atccacaaaa
    14161 tcaatatgga aaccattttt aaatagaatt tcacctataa aaccacgacc gatattaccg
    14221 gcaccaaaat gaacagaatg tttcattcaa tttctccttt tcctatttga gggacatata
    14281 tactagatga caaatgacga aattcaatta ttcaacagca tcaaataagc gcaatacttc
    14341 ctcttttgac tgagcatctg ctagtttaag aacattatcc acatctgcac agaagataga
    14401 aattttctga ataatttcta agtgttcatt accaatacca gcaataccaa aaagaaccgt
    14461 tgccacttga gggttagata cattcccaaa atcaacccct ctagggactt gaacgactgt
    14521 aataccagac ttgaggacat cattttttgc tgcatctgtt ccatgcggta tggcgataaa
    14581 gttacccatg taaacagata gctctttatc tcgctcaatc atggcttcaa tatagtcttc
    14641 attaacatat ccaccctcat aaagaacttg cccacaataa caaatagctt cctccttgtt
    14701 agaaaattgt ttattaagct taatcaaatg tttttcaagt ttcatattag ttctccaatt
    14761 tcttaatttt ttcgttaaaa atagtattta gcatctgata aataatggat tgatttcccg
    14821 tcttgtaaat ctctgtataa agatgatttt caataatcga ctgactaata gctgtcatta
    14881 aatctctagc ttcctcgcta gcttctttag acattagcat tagcagacac cttttgacct
    14941 cttcttcctc tcgtttcatt gacaatgcgg agataggtag tttgagttca aacatagtaa
    15001 aactatttgt tgttactttg ctagactgac tatgtaaaag caccagacca gtattaggaa
    15061 tagccatagg actattctgg aagtgagata acaattttct tgttaggtaa tctctgtcac
    15121 tcacattctt ctgatattgg atgatttgtt ctaccgtgtg ctcaaatgat tgattattct
    15181 ccaattgaac caactcgaat tgactcaaaa gctgactact agatattaaa taatcttgca
    15241 agtcataact tttctctgga gcgatagcat cacgcgcgac aattgtacga tgtgcctgta
    15301 catactgaag tcgttcctgt aattcaagca attctttgac ggttggaaaa ctagaaatta
    15361 caccgatttc ctgattagtc agcggcttgg tagataaaat ataatcatac tgactgagat
    15421 caatactgtg gtaatctact agagactgaa tatctatcaa ctctacaaaa ggagcaacac
    15481 tcttaatttt actgactaat aaatctctag tgacccgacg ttcatccgtt aaaagcaaaa
    15541 cacggactgg ataaatctct ggactacggc ctaagctaga gataaaatgt agggcaatca
    15601 tgccatactc atactctgta tgaagatatt tcggaaaaat atcattcact aaaagactga
    15661 tgactgtata aagaaattta ttcctttcaa ctaaaatctg gacagattct ggcaaatttt
    15721 caccctgaaa aaggataggg acgcctaaac tgagccgaat atgatggaaa agaaaattga
    15781 ataaaacctt gtccttaaaa aagtcaatct tggtatacat ggaaaccgta tcaatcagat
    15841 ttgaaatatt gtagaaaaat tcaccatcaa atttctccgt aaagagcgga ttgtcctgac
    15901 gtttaatgat taattcatcc aagatgctcg caaaatagat aatttcctga atactataaa
    15961 attgtgcagt ctgcttagag taagtttgaa aaattttttg agaaatttcc aaagcctgct
    16021 tactagtatt aggtgaattt tcaatgtttt gctcctgacc tataagagat aacaagatcg
    16081 caaaaaacat cttcatccta gcatccatat ctggaaaacc tgacagttgc ttattaacaa
    16141 tctgactggc cagcctagtt ctatctgctt ctaaaatatc aaagctccca aaattaccgg
    16201 ttgaaaaatc tgctactgag atacagtttg tcagtaaaat agccaaaaat cttctcttac
    16261 caactgaatc accagaaatc cgataacctt tttgtcgttc aattttcaga tcaaagtcta
    16321 aaagacgctt atcaatatct gaaatatcct gaataatagt tacattactg actttcgtgc
    16381 actcttgcaa tgcttcattg gtgacaaaac cgctctcagt cagaaggcga taggtaatca
    16441 actcttgtct ttcttgggga ctatactcaa ctaacacttc aagttctgtc ggcaaatcat
    16501 ccaactctcc agtcaaaata tagtatttcc catgcttcgt tatttcgatt ccatattgct
    16561 ccatgctatc tgtcaaatct gataaagttc gataaattgt tctagatgaa acctgtaaga
    16621 tttcagtcat atcttgcatt gaaagcttcc ctacatgtag gaaagccttc aataattgtt
    16681 cttctcgttt ggttaatagc attcgtaatt tagaaacctc tagttctatt tgtacattct
    16741 agcagccatt ttgtcatatt ctggtgttgt tactaaacta tccacaataa gaaattgaga
    16801 attcggtgct gcttgctgca cttctgcctg taaagaaata gttgttacaa tcattatgtt
    16861 tttagaatta aattcaccta attctgaaat tttggcagta gaaactggaa tacgaatatt
    16921 cttgtttcta aagatagccc gaatcgtttc acagcccata gttgcagttc cctgtgcttt
    16981 accataagca actactacag catcaatatg gttaaggtca atttcctgac tatctactgg
    17041 tgctgaagtt ggtatatctc cttcaatttc tgctattgga aaagctcctg ttaatgaagc
    17101 tacaatttca tcataacgag gggacgctaa gaaattatca acagaaacat gaatagcact
    17161 tggactcttg tctttagctc ttggtgtcag ttcttcctga gtaacaatta atgtttttgg
    17221 tgtatcaagc aaatttgaga ttgcctgatt agatactgga atctctagac ctgctttttt
    17281 aaccttatct cgaagaatac tagctcccat agcagagctt cccataccag catcgcaggc
    17341 gaaaatgatt ttttccactg agtctgtcga aacaactgca tcaacagaag ttgatactaa
    17401 ctgaccttta gactgagcct tagctgcttg ggtagccgcc tgagcagctt cgagcgaatc
    17461 ctcagttgac ttgtctgcat gaagaataag ggctgctaca aggaaagaaa caactgctgc
    17521 cactaaaaca cctaaaagaa catttagatg aggccaaaca ccttttggcg ccgtagccat
    17581 aatcgcaata atagaacctg gtgaagctgg agatttaaga ccagcgtcta agagttgaaa
    17641 agtaaaagtt ccagagatac ctcctgccat agcagctaaa aatagagtag gcttcatcat
    17701 aacataagga aagtaaattt catgaatccc tccgaagaaa tgaataacca ttgcccccca
    17761 agaagaagat ttagcagaac ctttaccgaa tacagcataa gctaatagaa ttcccaggcc
    17821 tggtccagga ttagcttcca ataggaagag aattgactta ccagcttgag ctacctgttc
    17881 tactcccaga ggagtaaaaa tgccatgatt gagggcatta ttgaggaaaa ggactttagc
    17941 cggttcgatg ataatattag ccataggaag gaggcgagca ttgacaatag cctcaacacc
    18001 attcccaaca gctccagtaa gagtcgatac gactggaccg attgcgtaga aagccaaaag
    18061 caataatgca aaaccaacga gaccagctga gaagttatta actaacattt caaatccggg
    18121 acgaattttt tcctggaact tctcatcaaa tttcttgata gtccatcctc ccagtgggcc
    18181 cattaccata gctccgataa acataggaac actagaacct gtgattgcac caacagtagc
    18241 aatagctcct acaacggcac cacgttggcc atggatcata tatccacctg tgtaaccaat
    18301 caggattggc aataaatacg ttaacatagg accaacaaca gtagctaact gttcatttgg
    18361 cagatagcca tcagcgataa agagggcagt caatactccc caagcaataa atgctccaat
    18421 attgggcata accatatttg aaagcgatgt ccctagtttt tgaaccctga ccttcaatga
    18481 tactttttct tccattagat catcctcctt ttcttaaaac tagtatatac aaagttaaaa
    18541 acctttaaaa ctaaagtttt gtcacagatt ttgtgtcaaa acattacttt tgacgaggct
    18601 gggcaaaaag gcttaaaaat tataaaacgc atcatatcag gtgtacatga actacacccc
    18661 aaaagttaga cagaaaaaat ctaacttttg gggtgttttt attatgaaa
//
LOCUS       DAVLXH010000043        18119 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00028199
            SAMN33607166-rid17955573.denovo.043, whole genome shotgun sequence.
ACCESSION   DAVLXH010000043 DAVLXH010000000
VERSION     DAVLXH010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607166
            Sequence Read Archive: SRR23725544
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18119)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18119)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721421.1
            Genome Coverage       :: 115x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:42:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,210
            CDSs (total)                      :: 2,161
            Genes (coding)                    :: 2,023
            CDSs (with protein)               :: 2,023
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 73 of 138
            Pseudo Genes (incomplete)         :: 60 of 138
            Pseudo Genes (internal stop)      :: 40 of 138
            Pseudo Genes (multiple problems)  :: 31 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18119
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607166-rid17955573.denovo.043"
                     /strain="AUSMDU00028199"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1349"
     gene            361..1407
                     /gene="pheS"
                     /locus_tag="VYO11_001575"
     CDS             361..1407
                     /gene="pheS"
                     /locus_tag="VYO11_001575"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HEV1596117.1"
                     /translation="MSTIEEQLKALREETLASLKQITAGNEKEMQDLRVSVLGKKGSL
                     TEILKGMKDVSAEMRPIIGKHVNEARDVLTAAFEETAKLLEEKKVAAQLASESIDVTL
                     PGRPVATGHRHVLTQTSEEIEDIFIGMGYQVVDGFEVEQDYYNFERMNLPKDHPARDM
                     QDTFYITEEILLRTHTSPVQARAMDAHDFSKGPLKMISPGRVFRRDTDDATHSHQFHQ
                     IEGLVVGKNISMADLQGTLQLIVQKMFGEERQIRLRPSYFPFTEPSVEVDVSCFKCGG
                     EGCNVCKKTGWIEIMGAGMVHPRVLEMSGIDATVYSGFAFGLGQERVAMLRYGINDIR
                     GFYQGDVRFSEQFK"
     gene            1407..1916
                     /locus_tag="VYO11_001576"
     CDS             1407..1916
                     /locus_tag="VYO11_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1596118.1"
                     /translation="MIRKVEMADVEVLAKIAKQAFRETFAYDNTEEQLQEYFEEAYSL
                     KTLSTELGNPDSETYFIMHEEEIAGFLKVNWGSAQTERELEDAFEIQRLYVLQKFQGF
                     GIGKQLFEFALELATKNSFSWAWLGVWEHNTKAQAFYNRYGFEKFSQHHFMVGQKVDT
                     DWLLRKKLR"
     gene            1993..4398
                     /locus_tag="VYO11_001577"
     CDS             1993..4398
                     /locus_tag="VYO11_001577"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HEV1596119.1"
                     /translation="MLVSYKWLKELVDIDVPSQELAEKMSTTGIEVESVESPAADLSK
                     IVVGEVLSCEDVPETHLHVCQVNVGEEEARQIVCGAPNVRAGIKVMVALPGARIADNY
                     KIKKGKIRGLESLGMICSLGELGISDSVVPKEFADGIQILPENTVPGEEVFSYLDLDD
                     EIIELSITPNRADALSMCGVAHEVAAIYDKAVNFKEFTLTETNEAAADALSVSIGTDK
                     APYYAARILDNVIIAPSPQWLQNLLMNEGIRPINNVVDVTNYILLYFGQPMHAFDLDT
                     FEGTDIRVREARAGEKLVTLDGEERDLDVNDLVITVADKPVALAGVMGGQATEISEKS
                     SRVVLEAAVFNGKSIRKTSGRLNLRSESSSRFEKGINVATVNEALDAAASMIAELAGA
                     TVRKGIVSAGELDTSDVEVSSTLADVNRVLGTELSYADVEDVFRRLGFGLSGNADSFT
                     VSVPRRRWDITIEADLFEEIARIYGYDRLPTSLPKDDGTAGELTVTQKLRRQVRTIAE
                     GAGLTEIITYALTTPEKAVEFTAQPSNLTELMWPMTVDRSVLRQNMISGILDTVAYNV
                     ARKNKNLALYEIGKVFEQTGNPREELPNEINSFAFALTGLVAEKDFQTAAVPVDFFYA
                     KGILEALFTRLGLQVTYTATSEIASLHPGRTAVISLGDQVLGFLGQVHPVTAKAYDIP
                     ETYVAELNLSAIEAALQPATPFVEITKFPAVSRDVALLLKAEVTHQEVVDAIQAAGVK
                     RLTDIKLFDVFSGEKLGLGMKSMAYSLTFQNPEDSLTDEEVARYMEKIQVSLEEKVNA
                     EVR"
     gene            complement(4466..5467)
                     /locus_tag="VYO11_001578"
     CDS             complement(4466..5467)
                     /locus_tag="VYO11_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000597989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HEV1596120.1"
                     /translation="MIKTFLSALSVILFVIPIIAYSFFPSSNLNIWLSTRPILAQIYA
                     FPLATATMASILSFVFFSLSFYKKNKQIRFYSGILLLLSLILLLFGTDKTLSSASNKT
                     KTLKLVTWNVANQIEAQHIERIFSHFDADMAIFPELATNIRGEQENQRIKLLFHQVGL
                     SMANYDIFTSPPTNSGIAPVTVIVKKSYGFYTEAKTFHTTRFGTIVLHSRKQNIPDII
                     ALHTAPPLPGLMEIWKQDLNIIHNQLASKYPKAIIAGDFNATMRHGALAKISSHRDAL
                     NALPPFERGTWNSQSPKLFNATIDHILLPKNHYYVRDLDIVSFQNSDHRCIFTEITF"
     gene            5614..6017
                     /locus_tag="VYO11_001579"
                     /pseudo
     CDS             5614..6017
                     /locus_tag="VYO11_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            6143..6409
                     /locus_tag="VYO11_001580"
     CDS             6143..6409
                     /locus_tag="VYO11_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1596121.1"
                     /translation="MEGCPSELFSKEEILESDMRVAIMSELIEARYEQGISQKKLEEV
                     SGISQPVIARMETGESSLQLDTVLKVLTSLGKTLAVVPLEQGKS"
     gene            6670..8919
                     /gene="metE"
                     /locus_tag="VYO11_001581"
     CDS             6670..8919
                     /gene="metE"
                     /locus_tag="VYO11_001581"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HEV1596122.1"
                     /translation="MSTTIIGFPRLGEFRELKFTTEKYFRKEISEEELLAAAKDLRAK
                     HWNIVKEKGITEIPSNDFSHYDNFLDAAFLFNVVPASVQNLDLSDLERYFALGRGYQG
                     EKGDVRALPMKKWFNTNYHYIVPKFEKDTQVKLAGHKIFDEFQEAKELGLNTRPVLVG
                     PFTFLQLSDFEEGVKADDFVDSLVVAYQEVFAKLAELGATRIQLDEAALVKDLTAEEK
                     ALFLNLYNKLLADKKGLEVLLQTYFGDVRDVYADLVNLPVDAIGLDFVEGKKTLELVK
                     GGFPADKTLYAGIVNGKNIWRNNYEKSLAVLEQIPAENIVLTSSCSLLHVPFTTANEE
                     FEPALLNHFAFAVEKLDEIRDLDAIRNGQGSEALAANKELFATERVGENAELRARIAG
                     LTDADYTRLPAFAEREAIQEEAFKLPALPTTTIGSFPQTKEVRAKRLAYRKGELSQKE
                     YDAFLAETIDEWIKWQEDIDFDVLVHGEFERNDMVEYFGQNLSGYLFSKNGWVQSYGM
                     RGVKPPIIWGDVTRLNPITVKWSSYAQSRTNKPVKGMLTGPVTILNWSFPREDISIKD
                     STLQIALAIKDEVLDLEAAGVKIIQIDEAALREKLPLRRSDWYEDYLDWAIPAFRLVH
                     STVASDTQIHTHMCYSEFTDIIPAIDNMDADVISFEASRSNLEILDELKAKNFQTEVG
                     PGVYDIHSPRVPNEGEIDNTIEAILAKVPSKKVWINPDCGLKTRGIPETKESLIRLVE
                     AAKAAREKL"
     gene            8983..9849
                     /gene="metF"
                     /locus_tag="VYO11_001582"
     CDS             8983..9849
                     /gene="metF"
                     /locus_tag="VYO11_001582"
                     /EC_number="1.5.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000089969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase [NAD(P)H]"
                     /protein_id="HEV1596123.1"
                     /translation="MSCQTPSLSFEVFPPNPAVGNDNIILALQDMQELAPHFISVTAS
                     NNKFNIKETTVRLADFIQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALR
                     GDIIPDVEPQKDFRYATDLIELIKEQAPHFDIIGACYPEGHPDSPNQISDIQNLKKKV
                     DAGCSSLVTQLFFDNEHFYDFQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIH
                     LPRKFKAILDKYEHDPESLRAAGLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQ
                     ATHALFNHQSLG"
     gene            10534..12747
                     /gene="pnp"
                     /locus_tag="VYO11_001583"
     CDS             10534..12747
                     /gene="pnp"
                     /locus_tag="VYO11_001583"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001854499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HEV1596124.1"
                     /translation="MAKQVFQTTFAGRELIVETGQVAKQANGSVVVRYGESTVLTAAV
                     MSKKMATGDFFPLQVNYEEKMYAAGKFPGGFMKREGRPSTDATLTARLIDRPIRPMFA
                     EGFRNEVQVINTVLSYDENASAPMAAMFGSSLALSISDIPFDGPIAGVQVGYVDGQII
                     INPSQEQAEQSLLELTVAGTKHAINMVESGAKELSEEIMLEALLKGHEAVKELIAFQE
                     EIVAAVGKEKAEVELLHVDAELQAEIIAAYNSDLQKAVQVEEKLAREAATQAVKDQVT
                     AVYEEKYADHEEFDRIMRDVAEILEQMEHAEVRRLITEDKVRPDGRKVDEIRPLDAVV
                     DFLPRVHGSGLFTRGQTQALSVLTLAPMGETQIIDGLDPEYKKRFMHHYNFPQYSVGE
                     TGRYGAPGRREIGHGALGERALAQVLPSLEEFPYAIRLVAEVLESNGSSSQASICAGT
                     LALMAGGVPIKAPVAGIAMGLISDGNNYTVLTDIQGLEDHFGDMDFKVAGTRDGITAL
                     QMDIKIQGITAEILTEALAQAKKARFEILDVIEATIPEVRPELAPTAPKIDTIKIDVD
                     KIKIVIGKGGETIDKIIAETGVKIDIDEEGNVSIYSSDQDAINRAKEIIAGLVREAKV
                     DEVYRAKVVRIEKFGAFVNLFDKTDALVHISEMAWTRTNRVEDLVEIGDEVDVKVIKI
                     DEKGRIDASMKALLPRPPKPEHDEKGEKSERPHRPRHHKDHKPKKEFTETPKDSE"
     gene            12763..13380
                     /gene="cysE"
                     /locus_tag="VYO11_001584"
     CDS             12763..13380
                     /gene="cysE"
                     /locus_tag="VYO11_001584"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000539958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HEV1596125.1"
                     /translation="MGWWRETIDIVKENDPAARTTLEVLLTYPGVKALAAHRLSHFLW
                     KHSFKLLARMHSQFWRFWTQIEIHPGAQIDSGVFIDHGSGLVIGETAIVEKGVLLYHG
                     VTLGGTGKDCGKRHPTVRKGALISAHAQVIGPVEIGENAKVGAAAVVVADVPSDVTVV
                     GIPAKIVRLHGKKDEPVIHAVEEKREYYVNKLEQAKDASHRSSGL"
     gene            13392..14276
                     /locus_tag="VYO11_001585"
     CDS             13392..14276
                     /locus_tag="VYO11_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1596126.1"
                     /translation="MIQARNKLSQEELSEAKKVINCCQNYDGTYRDPYLSNMLNFDPN
                     MPAFFLYYEKGKLVGLLTVYADDQDVEVTILVHPGHRRQGIARALFTSFERETASFPI
                     RSVTFQTERIFLENHPDFASNWGLIEDEETETWLGKDRRPYPLANVSHLEILLADSSY
                     QDQISQLKFQAFSEEHESREVVDRYVAEALKDPESRLYILLKAGQVIGTCTVDLSSDT
                     NYFYGLAISEPERGKGYGSYLAKSLVNQLIEQNDKEFQIAVEDSNVGAKRLYEKIGFV
                     KQTQVVYLNEKGARDSEV"
     gene            14363..15706
                     /locus_tag="VYO11_001586"
     CDS             14363..15706
                     /locus_tag="VYO11_001586"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002916477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HEV1596127.1"
                     /translation="MIKIYDTMSRDLREFVPIEDGKIKMYVCGPTVYNYIHVGNARST
                     VAFDTIRRYFEYRGYKVAYISNFTDVDDKIINRAREEGITPQEVADKYIAAFREDVTA
                     LGVKPATRHPRVVEFMADIIRFVEDLIEKGFAYESQGDVYFRVEKSHNYAKLANKTLE
                     DLELGASGRTDEETARKENPVDFALWKSSKPGEISWDSPWGPGRPGWHIECSVMSTEI
                     LGDTIDIHGGGADLEFPHHTNEIAQSEAKTGKAFANYWMHNGFVNIDNVKMSKSLGNF
                     ITVHDALKTLDGQVLRFFFATQHYRKPINFTEKAVRDAETNLKYLKNTYEQPFTGNVD
                     AQELQNFKDKFVAAMDEDFNAANGITVVFEMAKWINSGNYDASVKQALADMLEIFGIV
                     FVEEVLDAEIEDLIQKRQEARANRDFATADQIRDQLVTQGIKLLDTKDGVRWTRD"
     gene            15699..16085
                     /locus_tag="VYO11_001587"
     CDS             15699..16085
                     /locus_tag="VYO11_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HEV1596128.1"
                     /translation="MIDVNLINGIALAFEGDAVYSMYIRRHLILKGMTKPNKLHQEAT
                     KYVSAKAQARLIALMLEEQVLTEKEEEIYKRGRNTNSHTKAKNADVVTYRMSTGFEAV
                     MGYLHMTENLERLESLVSWCIQKVEG"
     gene            16089..16973
                     /locus_tag="VYO11_001588"
     CDS             16089..16973
                     /locus_tag="VYO11_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PucR family transcriptional regulator"
                     /protein_id="HEV1596129.1"
                     /translation="MREKELQDWFPEARISDQPVEKEGYLTLPLASQQWILLEEAGLS
                     EREKQLVALLTQQEQARSLNPWYSYLVEGKGQAPQVFKKIQLVYCHLSYFQQENLTSW
                     LDMMRTLFPNCQTVLQVGAQDYVFVLQQDKYTSVRDILSDTIEAVEYDFGLRLSIMLG
                     QVWSQTGHQALSDLIKAERDLFKTWWRQGHQGVHTFSQLYLWSMGERLVDLKPIKECL
                     HQMILDQDQIQEIILSLWENSAVLTKTAQQLYLHRNSLQYKIDKWEELTGLQLKELTD
                     LTLCYQLILGSLSTIVGL"
     gene            17110..17709
                     /locus_tag="VYO11_001589"
     CDS             17110..17709
                     /locus_tag="VYO11_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001166174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1596130.1"
                     /translation="MQILCYFTITVVAKPNNSGEVHLDVSIEDNQGGSGYNFSSVSSS
                     SQTAKYEGTGYNNNSSLYITIDKTSDATALLKLKLNNVDNQPATEVPSSGITVKLNAK
                     DNAGNWTSASNKKEVTVKIVSAKPTYPDKILVKNPDNIKDTEKNAIIEKLKEANKNHP
                     AGAPTFAKGEGEHANDIVATYSDGTTYYVPLNDVTKYAR"
     gene            17852..18022
                     /locus_tag="VYO11_001590"
                     /pseudo
     CDS             17852..18022
                     /locus_tag="VYO11_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
BASE COUNT         5452 a         3481 c         4100 g         5086 t
ORIGIN      
        1 attaatttta ctttcccaat cgatttgttt tcatcttatt tcaatccgct ataaagttag
       61 ataagaataa gctaacaagc agaagtaaga taggtcttgc aagaatggta aaaatctgat
      121 aaactaagta gtaattgaat aggaatctga aagactagta gcccaaggga agtatatcag
      181 ggaggagagc cgtgactgca agctctctat atgaaagctg ggtgaattca cttgcgcatg
      241 gatttagaaa tgaaggtctg acttgtcaga tgaaaacgga tggtaccgcg tgtcaacgct
      301 ccgagtggag tttttggcat gtggttttct ttttatctac gagagactga tggaggaaat
      361 atgtcaacta ttgaagaaca attaaaagcg cttcgcgaag aaacgctggc tagcttgaag
      421 cagattactg ctggaaatga aaaagagatg caagatttgc gtgtctctgt ccttggtaaa
      481 aagggttcgc tcactgaaat cctcaaaggg atgaaagatg tttctgctga gatgcgtcca
      541 atcatcggga aacacgtcaa tgaagctcgt gatgtcttga ctgctgcttt tgaagaaaca
      601 gctaagctct tggaagaaaa gaaagtcgcg gctcaactgg ctagcgagag tatcgatgtg
      661 acgcttccag gtcgtccagt tgcgactggt caccgtcacg ttttgacaca aaccagtgaa
      721 gaaatcgaag atatcttcat cggtatgggt tatcaagtcg tggatggttt tgaagtagag
      781 caagactact ataactttga acgtatgaac cttccaaaag accacccagc tcgtgatatg
      841 caggatactt tctatatcac tgaagaaatc ttgctccgta cccacacgtc tccagttcag
      901 gcgcgtgcta tggatgccca tgatttttct aaaggtcctt tgaagatgat ctcgccaggg
      961 cgtgtcttcc gtcgcgatac ggacgatgcg acccacagtc accaattcca ccaaatcgaa
     1021 ggcttggtag ttgggaaaaa tatctctatg gctgatcttc aaggaacgct tcagttgatt
     1081 gtccaaaaaa tgtttggtga agagcgtcaa attcgtttgc gtccatctta cttcccattc
     1141 acagagccat ctgttgaggt ggatgtttct tgcttcaagt gtggtggaga aggctgtaac
     1201 gtatgtaaga aaacaggttg gatcgaaatt atgggagccg gtatggttca cccacgtgtc
     1261 cttgaaatga gtggtatcga tgcgactgta tactctggtt ttgcctttgg tcttggacaa
     1321 gagcgtgtag ctatgctccg ttatggaatc aacgatatcc gtggattcta ccaaggagat
     1381 gtccgcttct cagaacagtt taaataatga ttagaaaagt agaaatggca gatgttgagg
     1441 tgttggctaa aattgccaaa caagcctttc gtgaaacctt tgcgtatgat aatacggaag
     1501 agcagttaca ggaatacttt gaagaggctt atagtctgaa aactttgtca actgagttgg
     1561 gaaatcctga ctctgaaacc tatttcatta tgcatgagga ggagatagct ggttttctca
     1621 aagtcaactg gggaagtgct caaactgaga gagaattaga ggacgctttt gaaattcaac
     1681 gcctctatgt gctacaaaaa ttccaaggat ttggaatagg taagcaactg tttgaattcg
     1741 cacttgaact tgctacaaaa aatagttttt cttgggcttg gctaggtgtt tgggagcata
     1801 atacaaaagc tcaagcgttt tataatcgat atggttttga aaaatttagc caacatcatt
     1861 ttatggttgg tcaaaaagta gatacggatt ggttactgag aaagaaatta aggtaagaag
     1921 aggattcttc tattgaaatg ataggaaagg aaaagaacca gtgtggcaat ggtcattctg
     1981 gagaactaaa ttatgcttgt atcttataaa tggttaaaag aattggtgga cattgatgtg
     2041 ccatcacagg agttggctga aaaaatgtca accacaggga tcgaggtaga gagtgtcgaa
     2101 tcaccagctg ctgatctctc aaaaattgtt gtcggtgagg tcttgtcttg cgaagatgtg
     2161 ccagagactc acctccatgt ttgtcaggtt aacgttggcg aagaagaagc ccgtcagatc
     2221 gtttgtggtg ccccaaatgt gcgtgctggg atcaaggtca tggtggctct tccaggagct
     2281 cgtatcgctg ataactacaa aatcaaaaaa ggaaaaatcc gtggtttgga gtcacttgga
     2341 atgatctgtt cacttggtga attgggaatt tctgactcag ttgtgcctaa ggaattcgca
     2401 gatggcatcc aaatcttgcc agaaaatacc gtgccaggtg aggaagtctt ttcttaccta
     2461 gacttggatg atgaaatcat cgaactttcc atcacaccaa accgtgcaga tgccctttct
     2521 atgtgtggag tggctcacga agtggcagcc atctatgaca aggcagtcaa ctttaaagaa
     2581 tttactctaa cagaaactaa tgaagctgcg gcagatgccc tttctgtcag cattgggaca
     2641 gacaaggcgc cttactatgc agctcgtatc ttggacaatg tgattatcgc accaagtcca
     2701 caatggttgc aaaaccttct catgaacgaa ggcatccgtc ccatcaataa cgttgtagac
     2761 gtgacaaact acatcctgct ctactttggt caacctatgc atgcttttga cttggacaca
     2821 tttgaaggga ctgacatccg tgtgcgtgaa gcgcgtgctg gtgaaaaatt ggtgaccttg
     2881 gacggtgaag aacgtgactt ggacgtgaat gacctagtca tcactgttgc agacaagcca
     2941 gtagcccttg caggtgtcat gggtggtcaa gcaacagaaa tctctgaaaa atctagtcgt
     3001 gttgtccttg aagctgctgt tttcaatggt aaatctatcc gtaagacaag tggtcgcctg
     3061 aaccttcgtt cagaatcgtc ttctcgcttt gaaaaaggca tcaatgtggc aacagtcaat
     3121 gaagcccttg atgcggcagc tagcatgatt gcagaacttg caggtgcgac ggtgcgtaag
     3181 ggtatcgttt cagcgggtga gcttgatacc tctgatgtgg aagtttcttc aacccttgct
     3241 gatgttaacc gtgtcctcgg aactgagctg tcttatgctg atgtcgaaga cgtcttccgt
     3301 cgtcttggtt ttggtctttc tggaaatgca gacagcttta cagtcagcgt accacgtcgt
     3361 cgttgggata tcacaatcga agctgacctc tttgaagaaa tcgctcgtat ctatggatat
     3421 gaccgcttgc caactagtct accaaaagac gatggtacag ctggtgaatt gactgtgaca
     3481 caaaaactcc gccgtcaagt tcgtaccatt gctgaaggag caggtttgac agaaatcatc
     3541 acctatgctc taacaactcc tgaaaaagca gttgagttta cggctcaacc aagtaacctt
     3601 acggaactca tgtggccaat gactgtggat cgttcagtcc tccgtcaaaa tatgatttca
     3661 ggtatccttg ataccgttgc ctacaacgtg gctcgtaaga ataaaaactt ggccctttac
     3721 gagattggaa aagtctttga acaaacaggt aatccaagag aagaacttcc aaatgaaatt
     3781 aacagttttg cctttgcctt gacaggcttg gttgctgaaa aagatttcca aacagcagca
     3841 gttccagttg atttcttcta tgctaaggga atccttgaag ccctatttac tcgcttggga
     3901 ctccaagtaa cctatacagc aacatctgaa atcgctagcc ttcatccagg tcgtacagca
     3961 gtcatttcac tcggtgacca agttcttggt ttccttggcc aagtgcatcc agtcactgct
     4021 aaggcttatg atattccaga aacgtatgta gctgagctta acctttcagc tatcgaagct
     4081 gcgcttcagc cagcgactcc atttgtagaa atcaccaaat tcccggcagt cagccgtgac
     4141 gttgcccttc tcctcaaggc agaagtgact catcaagaag ttgtagatgc tatccaagct
     4201 gccggcgtga aacgtttgac agatatcaaa ctctttgacg tcttctcagg tgagaaattg
     4261 ggacttggta tgaagtcaat ggcttatagc ttgaccttcc aaaatccaga agatagctta
     4321 acggacgaag aagtcgcacg ctatatggaa aaaatccaag tatcgctcga agaaaaagtg
     4381 aatgcagaag tgcgttaaac gatagtatga tacaaattcc ccctctagtt tatgaacact
     4441 agaggggtga ttttatataa aataattaaa atgtgatttc tgtaaaaata catctatgat
     4501 cagagttttg aaaacttaca atgtctaaat ctctaacata gtagtggttt ttaggcaata
     4561 agatatgatc tatcgttgca ttaaaaagtt ttggactttg gctattccaa gttcctcttt
     4621 caaaaggtgg aagtgcattc aatgcgtccc tatgagagct tatttttgca agtgctccat
     4681 gacgcatagt tgcattaaaa tcacctgcaa taatagcctt tggatatttt gaagccaatt
     4741 gattatgaat gatgtttaag tcttgcttcc agatttccat taaacctggc agaggaggag
     4801 cagtatgcaa ggcaatgata tctggtatat tttgttttct cgaatgtaat acaattgtcc
     4861 cgaaccgtgt tgtatgaaaa gttttagctt ctgtatagaa accataactt ttcttgacaa
     4921 tcacagtcac aggagctatt ccactattgg taggtggaga agtgaaaata tcatagttgg
     4981 ccatagaaag tccaacttga tgaaacaata gtttgattct ctggttttct tgctcacctc
     5041 tgatattggt agctagttca gggaatatag ccatatcggc atcaaaatgg ctaaaaattc
     5101 gctcaatatg ttgtgcttct atttgattag cgacgttcca agttactaat tttaaggttt
     5161 tagtcttatt tgatgcagaa gaaagggttt tatctgttcc gaataatagt aatatgagcg
     5221 atagtaagag caaaatgcca gagtaaaacc gtatttgttt atttttcttg taaaaagata
     5281 gggaaaaaaa tacgaaactt aaaatagaag ccatagttgc agtagctaag gggaaggcat
     5341 aaatctgtgc caagataggt ctggtagata gccaaatatt aagattagaa gatggaaaaa
     5401 aagaataagc tatgataggg ataacaaaga gaatgaccga aagggcagag agaaatgttt
     5461 taatcattgt gtgagtacct caatttgcaa tggttgctcg gagctaatgt gactttactt
     5521 gattgatatt ctttttcttg tcttcctcat agattaagta caacccaagt aaaaaagttc
     5581 aatttaagat tgaaatgatt aaaaggcaca gaaatgcaag acaattatac tacaaaaggc
     5641 aaacatttga caatcgatag ccgtcgctta atcgaacgat ggaaaaaaga aggaaaatca
     5701 aatagagaaa ttgcctctct acttggaaaa gctcctcaaa ctatccacac tgaaatcaag
     5761 cgtgggacag tccgacaatg tcttggaaaa gggcgcttca aagagattta ttctgccgac
     5821 tacgctcaac agtcttaaga aactaaagga aaagattctc cactatacat aaccaaaaat
     5881 tttcgcctga aatgatggtg atggctaaag gggttaacgt gggaatttca accatttact
     5941 attggattca tcgtggaaaa ttggggttaa gcaagcagga tctgctttat cctagaaaag
     6001 gaaaatcgct taagaaatag gctagcacca actttaaacc cgctggtcaa tctatcgaat
     6061 cataattcgc tcattttttt aaaaatacat agacgtaaaa aaaagagggt taagtgatga
     6121 agaatagtgc tattgggagt aattggaagg atgtccatct gagctcttta gcaaggagga
     6181 aatccttgaa agtgatatgc gagtggctat catgagcgag ttgattgagg ctaggtatga
     6241 acaaggaatc agtcagaaaa agctggaaga agtcagtgga ataagccagc ctgtcatagc
     6301 taggatggag acaggagaga gcagtcttca gttggatacg gtcttaaaag ttctaaccag
     6361 tctaggaaag acactagcag tcgttccact tgaacagggg aaaagttgac tagaatcagt
     6421 tatagtcttt tctaataaca ggtcatagtc acttataaga attactaata acatgtttta
     6481 gtattctaat tggaatatag ctgtaaagta agaattacaa aggatttgag atgtttgctt
     6541 caagtctttt tcttttgtcc gaaacagata tatagtttca aactatatca aaccctaatt
     6601 ttttacaatt atacagacgc tttcttttct gttaagatag tttcaacaac aaattttgga
     6661 ggacacatca tgtcaactac aatcatcggt ttccctcgtt tgggcgaatt ccgtgaatta
     6721 aaatttacaa ctgaaaaata ctttagaaaa gaaatctcag aagaagaact tttagcagca
     6781 gcaaaagact tgcgtgctaa acactggaac attgtcaaag aaaaaggcat cactgaaatt
     6841 ccatcaaatg acttttctca ctatgataac ttcctagatg cggctttcct tttcaacgtg
     6901 gtgcctgcat ccgttcaaaa cttggacttg tctgaccttg agcgctactt cgctttggga
     6961 cgtggttacc agggagaaaa aggggacgtt cgcgcccttc caatgaagaa atggttcaac
     7021 actaactacc actacatcgt tcctaaattt gaaaaagaca ctcaagtaaa attggctggt
     7081 cacaagattt tcgatgagtt ccaagaagca aaagaacttg gattgaacac tcgtcctgtt
     7141 cttgtaggtc ccttcacttt ccttcaattg tcagactttg aagaaggcgt gaaagcagac
     7201 gacttcgtag atagcttagt agttgcttac caagaagttt ttgctaaatt ggctgaactt
     7261 ggtgcgactc gcatccaatt ggatgaagcg gctcttgtaa aagacttgac agctgaagaa
     7321 aaagctctct tcttgaacct ttacaacaaa ctcttggctg acaaaaaagg tcttgaagtc
     7381 ttgcttcaaa cttatttcgg tgatgttcgt gacgtatacg ctgaccttgt aaacttacca
     7441 gtagatgcta tcggtcttga ctttgttgaa ggtaagaaaa ctcttgaact cgttaaaggt
     7501 ggcttcccag ctgacaagac tctctatgca ggtattgtca atggtaaaaa catctggcgt
     7561 aacaactacg aaaagagctt ggctgttctt gagcaaatcc cagctgaaaa catcgttttg
     7621 acaagctctt gctcacttct tcatgtgcca tttacaactg ctaatgaaga atttgaacca
     7681 gcactcttga accactttgc ctttgcagtt gaaaaattgg atgaaatccg tgacttggat
     7741 gctatccgca atggtcaagg ttcagaagct cttgcagcca acaaagaact ctttgcgact
     7801 gagcgtgttg gtgaaaatgc tgaacttcgt gcgcgtatcg ctggcttgac agacgcagac
     7861 tacactcgtt tgccagcctt tgcagaacgt gaagctatcc aagaagaagc ttttaaactt
     7921 ccagctcttc caacaacaac gattggttca ttccctcaaa caaaagaagt tcgtgccaaa
     7981 cgtttggctt accgtaaagg tgaattgtct caaaaagagt acgacgcttt ccttgctgaa
     8041 acgattgacg aatggatcaa gtggcaagaa gatattgact ttgatgtcct tgttcacggt
     8101 gaatttgagc gtaatgacat ggttgagtac ttcggtcaaa acttgtcagg atacctcttc
     8161 tctaaaaatg gatgggtaca atcatacggt atgcgtgggg taaaaccacc aatcatctgg
     8221 ggtgatgtca ctcgtcttaa ccctatcact gttaaatggt ctagctatgc acaaagtcgt
     8281 acaaacaaac ctgttaaagg tatgttgact ggacctgtta ccatcctcaa ctggtcattc
     8341 ccacgtgaag acatctctat caaggattct actcttcaaa tcgcccttgc tatcaaggat
     8401 gaagtgcttg accttgaagc tgctggtgtg aaaatcatcc aaattgatga ggctgctctt
     8461 cgtgaaaaat tgccactccg tcgtagtgac tggtacgaag attaccttga ctgggcaatt
     8521 cctgccttcc gcttggtaca ctcaacagta gcgtcagaca cacaaatcca cactcacatg
     8581 tgttactcag aatttacaga tatcatccca gctatcgata acatggatgc agacgttatt
     8641 tcctttgaag ccagccgttc aaaccttgaa atcttggacg aactcaaagc gaaaaacttc
     8701 caaacagaag tgggacctgg ggtttacgat atccactcac ctcgtgtacc aaatgaaggc
     8761 gaaatcgaca acacaatcga agccatcctt gctaaagtgc caagcaagaa agtttggatc
     8821 aaccctgact gtggtttgaa aacacgtggt atcccagaaa caaaagaaag cttgatccgc
     8881 cttgttgaag cagctaaagc tgcgcgtgag aaattgtaag attggatttc tctccataca
     8941 gtggttgttc aaaaagaaat caactagaaa aggttattac atatgtcatg ccaaacaccg
     9001 tcactctcat ttgaagtgtt ccctccaaac ccagccgtgg gtaatgataa cattatttta
     9061 gccttgcagg atatgcagga gttggctccc cattttatca gtgtaactgc cagcaataat
     9121 aaatttaata tcaaggaaac gacggttcgt ttggctgact ttatccaaaa tgacttggcg
     9181 attccgacca ttgcccactt gccagctatt tatctaacta aggacaaggt tgctgaaact
     9241 attgctgact tggacaaagt tggggtgcag aaaatcttgg ctcttcgtgg ggatattatt
     9301 ccagacgtgg aaccacaaaa ggatttccgc tatgcaaccg acttgattga gcttatcaag
     9361 gaacaagccc ctcactttga tattattgga gcttgctatc cagaagggca tccagattcg
     9421 ccaaatcaga tttcagatat tcaaaatctt aagaagaaag tggatgcagg ctgttcgagc
     9481 ctcgtaactc agctcttctt tgacaatgag cacttctatg attttcagga caagtgcatc
     9541 ttggctggga ttgatgttcc cattcatgca ggaattatgc caattctgaa tcgaaatcag
     9601 gctctccgac tcttgaagac ttgtgagaat atccatcttc cacgcaaatt taaagccatc
     9661 ttagacaagt atgagcatga ccctgagtcg ctcagagcag caggacttgc ctatgcagtg
     9721 gaccaaatcg tagacttggt aactcaggat gttgccggtg tgcatctcta tacgatgaat
     9781 aatgctgata cagcaaaata catccatcaa gcaacccatg ccttgtttaa tcaccagtct
     9841 ctaggataat aaaagcaaac cattcttctc aggtgagggg aatggttcct ttttaatggt
     9901 aaagacctca ctttttaaga aaaatatgat aaaataaatt ctgtacgtac ttgatacaaa
     9961 gatgaaggta ttaaataata caatgcattt aaactgtaag atttaacgac acgagtgagt
    10021 caaatcgatg ttatttgacg agagagttag taaagcattt agctaatcgc ccgatagcga
    10081 ttagcgtgaa agctttagat actttagtat taaacctttc taatgatgta tcttgaaaac
    10141 tgaacttgcc tacaactctg tggaaaaaga taaatctccc taggagcagt cgctccgtcg
    10201 ttcgatttcc tatcttcctt tgagttgctt gacggcttgg tatcttgatg acttgaattt
    10261 tggtctcatt tcttaggaaa aaagataagc ttcctagcac tcgtcgagtg cgaagtcacc
    10321 ttcctatttt tctacagaaa tgttcggcaa gccgaaccgt ccaaaatatc ttgtgtaatt
    10381 gaacacggcc gaaaagctgt gtaaaaaaga taaactgtct tgtcttcatc gaagacttcg
    10441 tcagtttcct atttttactt tgcttttgac gtccttggta tcttgatctt tgtaggcaag
    10501 gcgtataatt tcatcaatcc aaaggggatt aaaatggcaa aacaagtgtt tcaaacgact
    10561 tttgcgggtc gtgagttaat tgtagagact ggtcaggttg ctaagcaagc aaatggatct
    10621 gttgtcgtac gttacggtga gtcaactgtc ttgactgctg ccgttatgtc taagaaaatg
    10681 gcaactgggg atttcttccc actccaagtc aactacgaag aaaaaatgta tgcggctggg
    10741 aagtttcctg gtggctttat gaaacgtgaa ggacgtcctt caacagatgc gaccttgaca
    10801 gcgcgtttga ttgaccgtcc gattcgtcct atgtttgcgg aaggtttccg taatgaagtc
    10861 caagtcatca atacagtgct ttcttatgat gaaaatgcat ctgcaccaat ggctgctatg
    10921 tttggttcat ctttggcact gtctatttca gatattccat ttgacggacc aattgctggg
    10981 gtacaagtgg gatatgtaga tggccaaatc atcatcaacc caagtcaaga acaagcagag
    11041 caatctcttc ttgaattgac agtagctgga accaagcacg ctatcaacat ggtagagtct
    11101 ggtgccaaag aattgtcaga agaaatcatg ttggaagcgc ttcttaaagg gcacgaagct
    11161 gtcaaagaat tgattgcctt ccaagaagaa atcgttgctg ctgtcggtaa agaaaaagca
    11221 gaagtggaat tgcttcacgt ggatgctgaa ttgcaagctg aaatcattgc agcctacaac
    11281 agtgacctcc aaaaggcagt tcaagtagaa gagaaattgg cccgtgaagc tgcaactcaa
    11341 gcagtgaaag accaagtgac tgccgtttac gaagaaaaat atgcggacca cgaagaattt
    11401 gaccgtatta tgcgtgatgt ggctgaaatc ttggaacaaa tggaacacgc agaagtgcga
    11461 cgtttaatta cagaagacaa ggtgcgtcct gatggtcgta aggtcgatga aatccgtcct
    11521 ttggatgcgg ttgttgactt ccttcctcgt gtacatggtt caggtctctt tactcgtggg
    11581 caaactcaag ctctttcagt cttgaccttg gctccgatgg gagaaactca aatcattgat
    11641 ggtttggatc cagagtacaa gaaacgcttt atgcaccact ataacttccc tcaatattct
    11701 gtaggggaaa caggtcgtta cggtgcgcca ggtcgtcgtg aaatcggtca cggtgctctt
    11761 ggtgagcgtg ctcttgctca agtcttgcca agcttggaag aattcccata cgctatccgt
    11821 ctagtagcag aagttttgga atcaaacggt tcttcatctc aagcttctat ctgtgcggga
    11881 actcttgccc ttatggctgg tggtgtgcca atcaaggcgc cagtagctgg tattgctatg
    11941 ggacttatct cagatggaaa taactacaca gtattgacag atatccaagg tttggaagat
    12001 cactttggag atatggactt caaggttgca ggtactcgtg atgggattac agcccttcaa
    12061 atggatatca agattcaagg gattactgca gaaatcttga cggaggctct tgctcaagcc
    12121 aagaaagcgc gttttgaaat ccttgatgtc attgaagcaa ccattccaga agttcgtcca
    12181 gaattggctc caactgctcc gaaaattgat acgatcaaga ttgatgtgga caagattaag
    12241 attgtcatcg gtaagggtgg agaaaccatc gacaagatta ttgctgaaac aggtgttaag
    12301 attgatatag acgaagaagg aaatgtgtct atctactcta gtgaccaaga tgctattaac
    12361 cgtgccaaag aaattattgc tggtttggtt cgtgaagcca aagtggatga agtttaccgt
    12421 gctaaagtcg ttcgtatcga gaaatttggt gcctttgtta acctctttga taagacagat
    12481 gcccttgttc atatctctga gatggcttgg actcgtacca atcgtgtaga ggatttggta
    12541 gaaatcgggg atgaagttga tgttaaggtt atcaagattg atgaaaaagg ccgtatcgat
    12601 gcttctatga aggctcttct acctcgtccg ccaaaacctg agcatgatga aaaaggtgaa
    12661 aagtctgagc gccctcaccg cccacgtcat cacaaggatc acaaacctaa gaaagaattt
    12721 acagaaacac caaaagattc agaataagaa aaggagaaat gtatggggtg gtggcgcgaa
    12781 accattgata tcgtaaaaga aaatgatcca gcggcccgca ccactttgga ggttttgctg
    12841 acttatccag gtgtcaaggc cttggcggcc caccgtctct cgcattttct ctggaagcac
    12901 agcttcaaac tcttagctcg tatgcacagt cagttttggc gcttttggac tcagattgag
    12961 attcatccag gagcccagat tgattcaggt gtctttattg accatggttc tggtctggtg
    13021 attggagaga cagcgattgt tgaaaaaggc gttcttctct atcacggagt gactcttggg
    13081 ggaacaggga aagactgtgg caaacgccat ccgactgtac gaaagggagc cctcatatca
    13141 gcccatgccc aagttatcgg acctgtggaa attggtgaaa atgccaaggt cggtgctgca
    13201 gcagttgtcg tagcagatgt acctagtgat gtgacggttg tcggtattcc ggccaagatt
    13261 gtccgtcttc atggtaagaa agatgagcct gttattcacg cagtcgaaga aaaacgagag
    13321 tattatgtca ataaactcga gcaggctaaa gatgccagtc acagatcgtc tggtttgtag
    13381 aggataccta tatgattcaa gcaagaaaca agttaagcca agaggagcta tctgaggcga
    13441 aaaaagtaat taactgttgc caaaactatg acggtaccta tcgcgatccc tatctctcta
    13501 acatgcttaa ttttgaccca aacatgcccg cctttttcct ttattatgaa aaaggcaaac
    13561 ttgttggttt attaactgtc tatgcagatg accaagatgt agaagtgacg atactggttc
    13621 atccaggtca tcgccgtcag gggattgcgc gtgcattgtt tactagtttt gagagagaaa
    13681 cagcttcttt ccctattcgg tcagtcactt ttcagacaga acgtattttt ttagagaatc
    13741 atcctgactt tgccagtaac tggggactaa tcgaggatga agagacagaa acttggttag
    13801 gtaaggatag aagaccttat ccgttagcaa atgtttccca tcttgaaatt ttgttagcag
    13861 atagttcgta tcaggatcaa attagtcaat taaaatttca ggcattttca gaggaacatg
    13921 aatcgagaga agttgtggat agatatgtcg ctgaagctct gaaagatcca gaaagccgac
    13981 tatatatttt attaaaagct ggtcaggtta ttgggacttg cacggttgat ttatcgagcg
    14041 atacgaatta cttctacggt ttagcaatat cagaacctga acgtgggaaa ggctatggaa
    14101 gctacttagc aaaatccctt gtcaaccaac taattgagca aaatgataag gaatttcaga
    14161 ttgcagtgga agatagcaat gtaggtgcca aacgtttgta tgaaaaaatt ggctttgtca
    14221 aacagacaca ggtggtttat ctgaatgaga aaggagcaag ggattccgaa gtgtagagac
    14281 attcggactg aaatttactt gagctcttag tttagtgatg aaactaacag ttcttggatt
    14341 ttagctttcc tgattatgat ttatgattaa aatctatgac accatgtctc gtgatttgcg
    14401 agaatttgtc ccgattgagg acggcaagat caagatgtat gtttgtgggc caacggtgta
    14461 caactatatc cacgtgggaa acgcccgttc gacggtagct tttgatacga ttcgtcgcta
    14521 ttttgagtac cgtgggtata aggttgccta tatttccaat tttacagatg tggatgataa
    14581 gattatcaac cgtgccaggg aagaaggcat cacgcctcag gaggttgcgg ataagtacat
    14641 cgctgccttt cgtgaggatg tgacggcctt gggcgtgaaa cctgcgactc gccatccgcg
    14701 tgtagtggag tttatggcag acatcatccg ttttgtggaa gacttgatcg agaaaggctt
    14761 tgcctatgag agtcaagggg atgtctattt ccgtgtagaa aaatcccaca actatgctaa
    14821 attggctaat aaaaccttgg aagatttgga gctaggtgct tcaggtcgta ccgatgaaga
    14881 aacggctcgt aaggaaaatc ctgtagactt tgctctatgg aaatcttcca aaccaggtga
    14941 gatttcttgg gatagtcctt ggggacctgg acgtccgggt tggcatattg agtgttcagt
    15001 catgtcgaca gagattttag gtgataccat tgatatccac ggtggtggag ctgacctaga
    15061 gtttccacac cacaccaatg aaattgccca atctgaagct aaaacaggca aggcttttgc
    15121 taactactgg atgcacaatg gctttgtcaa tatcgacaat gtcaaaatgt ctaagtcctt
    15181 gggtaacttc attacggtac acgatgccct taaaactctt gatgggcaag tacttcgttt
    15241 cttctttgcg acccagcact accgtaagcc tatcaacttc acggaaaagg cagttcgcga
    15301 tgccgagacc aatctcaagt atctgaagaa tacttacgaa caaccattta caggaaacgt
    15361 ggatgcccaa gagttacaaa actttaaaga taagtttgta gcagctatgg atgaagattt
    15421 taatgctgcc aacggtatca cagttgtctt tgaaatggcc aaatggatca actcagggaa
    15481 ctatgatgca agtgtcaagc aagctcttgc agatatgtta gaaatttttg gaattgtctt
    15541 tgttgaggaa gttttggatg cagagattga agacttgatt caaaaacgcc aagaggcgcg
    15601 tgccaatcgt gactttgcga cagcagacca aatccgtgac caattggtta ctcaaggaat
    15661 taagctcctt gataccaagg atggagtgag gtggacacgt gattgatgtc aatctcatta
    15721 acgggattgc gctagccttt gagggggatg cggtgtattc tatgtatatt cgccgtcacc
    15781 tcatcctcaa aggtatgacc aaacccaata aactccatca agaagcaacc aagtatgtgt
    15841 cagccaaggc tcaggctcgc ctgattgctc tcatgttgga ggagcaggtc ctaacggaaa
    15901 aagaagaaga aatctacaaa cgtggccgca ataccaatag ccacacaaag gctaaaaatg
    15961 cagatgtcgt gacttatcgt atgtccacgg gatttgaagc ggttatgggc tatctccata
    16021 tgactgagaa tctggaacgt cttgagagtt tggtttcatg gtgcatccaa aaagtggagg
    16081 gctagaacat gagggaaaaa gaactacaag actggtttcc tgaggctcgg atttcagacc
    16141 aaccagtaga gaaagagggc tatctcacgc tccctttagc ttctcagcag tggattttgc
    16201 tggaggaagc tgggctcagc gagcgtgaaa agcagttggt tgcccttttg acccagcagg
    16261 agcaggctcg ttcgctaaac ccttggtatt cctatctggt tgaaggcaag ggacaggcac
    16321 cgcaagtttt taaaaagatt cagttggttt attgccatct ttcttatttt cagcaggaaa
    16381 atctgacttc ttggctagat atgatgcgga ctctttttcc gaattgtcag acagtgctac
    16441 aggtcggagc tcaggattat gttttcgtgc ttcaacaaga caaatacact tctgtaagag
    16501 atattttaag tgatacgatt gaagcggttg agtatgattt tggacttcgt ctttctatca
    16561 tgttgggtca ggtttggtct cagacaggac atcaagccct atcagactta atcaaagctg
    16621 agcgggattt gttcaagaca tggtggcgtc agggtcacca aggtgttcat actttttctc
    16681 agctctatct ttggagtatg ggagaaagac tcgtggactt gaagccaatt aaagaatgtc
    16741 tacaccagat gattttggat caagatcaga ttcaggaaat cattctctct ctttgggaaa
    16801 atagtgctgt tctcactaaa acagcccagc aactctatct gcaccgcaat tctctccaat
    16861 acaagattga taaatgggaa gagttgacag ggcttcagtt gaaagagttg accgacctga
    16921 ccttgtgtta tcaattgatt ttaggttctt tgtcaactat agttggtttg taaagaagtt
    16981 aatatttgga gaagaggatt gccatcttct ccatttttat gtgcagagtt atagtggctt
    17041 gatgctggga aagtacactg tgactgctaa aacattccta gaagctgctt tgatttccct
    17101 aatctattta tgcaaatttt atgttatttt actataacag ttgttgctaa gccaaataat
    17161 agtggggaag ttcatttaga cgtaagcatt gaagataatc agggaggtag tgggtataat
    17221 ttcagttctg tttcaagtag ctcacaaaca gctaaatatg aaggaactgg ttataataac
    17281 aattcatcat tatatataac gattgataaa acgtctgatg caacagctct tttgaaatta
    17341 aagttgaata atgttgataa tcaacctgct actgaagttc ctagttcagg aattactgta
    17401 aaattaaatg ctaaagataa tgctggaaac tggacaagtg cttcgaataa aaaagaagta
    17461 acagtaaaaa ttgtttctgc taaaccgaca tatccagaca aaatcttagt gaaaaatcct
    17521 gataatataa aagatacaga aaaaaatgcc attattgaaa aattgaaaga ggcaaataaa
    17581 aatcatccag caggagctcc aacctttgct aaaggtgaag gagagcatgc aaatgatatt
    17641 gtagcaactt attcagatgg tacaacttat tatgtaccgt taaatgatgt gacaaaatat
    17701 gcgaggtagt ggctgtacca ctcacttatt cacctccccg tgatttgtag tagtgatagg
    17761 ctttctcact attattataa aacaaaataa agatcacaac actttttcat tctgtgttgt
    17821 gccttgagtg aaacgaaagg aatgaattat aaatatgaaa agtatagtca ctagcataga
    17881 tgagcgcttg cgtactcgcc tacgagtgat tatctggaag caatggaaga agaaatcgag
    17941 acgattatgg ggattgctta agttaggggt tcctaaatgg atagcagata aggtatctgg
    18001 ctggggcgac cactatcaat tatagtaaaa tgaaataaga ataggacgaa tcgatcaggg
    18061 aagtcaaatc gatttctaac aatattttag aagtagaggt atattattct agtttcaat
//
LOCUS       DAVLXH010000044        17557 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00028199
            SAMN33607166-rid17955573.denovo.044, whole genome shotgun sequence.
ACCESSION   DAVLXH010000044 DAVLXH010000000
VERSION     DAVLXH010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607166
            Sequence Read Archive: SRR23725544
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17557)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17557)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721421.1
            Genome Coverage       :: 115x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:42:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,210
            CDSs (total)                      :: 2,161
            Genes (coding)                    :: 2,023
            CDSs (with protein)               :: 2,023
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 73 of 138
            Pseudo Genes (incomplete)         :: 60 of 138
            Pseudo Genes (internal stop)      :: 40 of 138
            Pseudo Genes (multiple problems)  :: 31 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17557
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607166-rid17955573.denovo.044"
                     /strain="AUSMDU00028199"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1349"
     gene            complement(127..1062)
                     /locus_tag="VYO11_001591"
     CDS             complement(127..1062)
                     /locus_tag="VYO11_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional biotin--[acetyl-CoA-carboxylase]
                     synthetase/biotin operon repressor"
                     /protein_id="HEV1596131.1"
                     /translation="MKSYQAVYQILSKETDYISGEKIAEKLSLSRTSIWKAIKRLEQE
                     GIEIDSIKNRGYKLMNGDLILPEILEENLPIKVSFKPETKSTQLDAKEAIDLGHEANT
                     LYLASYQTAGRGRFQRSFYSPQGGIYMTLHLKPNLPYDKLPSYTLLVAGAVYKAIKNL
                     TLIDVDIKWVNDIYLNNHKIGGILTEAMTSVETGLVTDIIIGVGINFTIKDFPQELKE
                     KAGSLFKATAPITRNELIIEIWRTFFETPAEELLYLYKKQSFILGKEVTFTLEQKDYK
                     GFAKDISENGKLLVQCDNGKEIWLNSGEISLNSWK"
     gene            complement(1059..1919)
                     /locus_tag="VYO11_001592"
     CDS             complement(1059..1919)
                     /locus_tag="VYO11_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000959966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HEV1596132.1"
                     /translation="MLVFSEYQTGTIDLALSFYGYEECTPNYSFGPAIRDTYVLHYIT
                     KGQGKFHYKGKIVDLKEGDFFLLKPEELTFYQADSKEPWAYYWLGITGGKSPDYFALS
                     QISDQSYLIQSETCHTQTTAKLISDIVRFAQITKSSELAQLHIMGQLHELMFHLGTIA
                     PNQKKKNISSTHQLYLECKRLIDSHYPQSLTIQDLAKELSVHRSYLSSVFKEFNTLSP
                     KEYLLYVRMHRARQLLENTQESIKVIAYSVGFSDPLHFSKAYKQYFNQTPSHTRKEYS
                     QYQLVRKATL"
     gene            2027..4189
                     /locus_tag="VYO11_001593"
     CDS             2027..4189
                     /locus_tag="VYO11_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000538915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HEV1596133.1"
                     /translation="MGVRIENNLFYVESKNLSLIIENRNGYLLLKHLGKTIKNYKGSN
                     SVYERDHAFSGNPTATNRTFSLDTQRQIFGQHGLGDFRKPTIQVQHNVTEVTDFRFVE
                     AKILKGQNGPQGLPSPHSMDDTETLVLMLEDSKAQLSLTLYYTTFNNDATIASYSKLD
                     NNSNQEVVIYKDFSFMADFPAADYEIVTLQGAYAREKTVRRQQVEQGIFSISSNRGAS
                     GHAQTPALLLCEQGVTEDAGNVFAIQLMYSGNFEAFVQKNQLNEVRVAIGINPENFSW
                     KLAPEEYFETPVALVTHSDQGLTGISHESQNFVLEHIMLSEFSKKERPILINNWEATY
                     FDFQREKLLELADEAKKVGIELFVLDDGWFGNRFDDNRALGDWVVNEEKLGGSLESLI
                     SAIHERGLQFGLWLEPEMISVDSDLYRQHPDWAIQVPGYEHTYSRNQLVLNLANPQVV
                     EYLKSVLDQFLSYHDIDYIKWDMNRNITKLGNGLTYLETQMQSHQYMLGLYELVSYLT
                     EKHSHILFESCSGGGGRNDLGMMRYFPQVWASDNTDAIARLPIQYGSSYLYPTISMGA
                     HVSAVPNHQMGRMTPLETRGLVAMMGNLGYELDLTNLSDEEKATIANQVNLYKELRPV
                     VQLGQQYRLINPDTVSNEAAVQFNYGNQTIVTYVRVLSVVETMETTLKLKNLDEEGLY
                     KLQENGEVYSGAELMYAGLTVILSQGDFLSRQYIFRKL"
     gene            4281..5540
                     /locus_tag="VYO11_001594"
     CDS             4281..5540
                     /locus_tag="VYO11_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEV1596134.1"
                     /translation="MEWYKKIGLLATTGLALFGLGACSNYGKSADDTVTIEYFNQKKE
                     MTKTLEEITRDFEKENPKIKVKVVNVPNAGEVLKTRVLAGDVPDVVNIYPQSIELQEW
                     AKAGVFEDLSNKDYLKRVKNGYAEKYAVNEKVYNVPFTANAYGIYYNKDKFEELGLKV
                     PETWDEFEQLVKDIVAKGQTPFGIAGADAWTLNGYNQLAFATATGGGKEANQYLRYSQ
                     PNAIKLSDPIMKDDIKVMDILRINGSKQKNWEGAGYTDVIGAFARGDVLMTPNGSWAI
                     TAINEQKPNFKIGTFMIPGKEKGQSLTVGAGDLAWSISATTKHPKEANAFVEYMTRPE
                     VMQKYYDVDGSPTAIEGVKQAGEDSPLAGMTEYAFTDRHLVWLQQYWTSEADFHTLTM
                     NYVLTGDKQGMVNDLNAFFNPMKADVD"
     gene            5554..6420
                     /locus_tag="VYO11_001595"
     CDS             5554..6420
                     /locus_tag="VYO11_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV1596135.1"
                     /translation="MKKVLQKYWAWAFVVIPLLLQAIFFYVPMFQGAFYSFTNWTGLT
                     YNYKFVGLNNFKLLFMDPKFMNAIGFTAIITIAMVVGEIALGIFIARVLNSKIKGQTF
                     FRAWFFFPAVLSGLTVALIFKQVFNYGLPAIGNALHIEFLQTSLLGTKWGAIFAAVFV
                     LLWQGVAMPIIIFLAGLQSIPTEITEAARIDGATSKQVFWNIELPYLLPSVSIVFILA
                     LKGGLTAFDQVFAMTGGGPNNATTSLGLLVYNYAFKNNQFGYANAIAVILFFLIVVIS
                     IIQLRVSKKFEI"
     gene            6434..7267
                     /locus_tag="VYO11_001596"
     CDS             6434..7267
                     /locus_tag="VYO11_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEV1596136.1"
                     /translation="MKQDERKALIGKYILLILGSVLILVPLLATLFSSFKPTKDIVDN
                     FFGFPTNFTWDNFSRLLADGIGGYYWNSVVITVLSLLAVMIFIPMAAYSIARNMSKRK
                     AFTIMYTLLILGIFVPFQVIMIPITVMMSKLGLANTFGLILLYLTYAIPQTLFLYVGY
                     IKISIPESLDEAAEIDGANQFTTYFRIIFPMMKPMHATTMIINALWFWNDFMLPLLVL
                     NRDSKMWTLPLFQYNYAGQYFNDYGPSFASYVVGIISITIVYLFFQRHIISGMSNGAV
                     K"
     gene            7578..9020
                     /gene="gtfA"
                     /locus_tag="VYO11_001597"
     CDS             7578..9020
                     /gene="gtfA"
                     /locus_tag="VYO11_001597"
                     /EC_number="2.4.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose phosphorylase"
                     /protein_id="HEV1596137.1"
                     /translation="MPIQNKTMLITYSDSLGNNLKDLYDNLEEHFGDAIGGVHLLPFF
                     PSTGDRGFAPVDYDEVDSAFGDWEDVKRLGERYYLMFDFMINHISRQSKYYKDYQEKH
                     EASEFKDLFLNWDKFWPENRPTQSDVDLIYKRKDRAPKQEIVFEDGSVEHLWNTFGEE
                     QIDLDVTKEVTMEFIRKTIQHLASNGCDLIRLDAFAYAVKKLDTNDFFVEPDIWDLLD
                     KVRDIAAEYGTELLPEIHEHYSIQFKIADHDYYVYDFALPMVTLYTLYSSRTERLAKW
                     LKMSPMKQFTTLDTHDGIGVVDVKDILTDEEIDYASNELYKVGANVKRKYSSAEYNNL
                     DIYQINSTYYSALGDDDVKYFLARLIQAFAPGIPQVYYVGLLAGKNDLKLLEETKEGR
                     NINRHYYSNEEIAKEVQRPVVKALLNLFSFRNRSEAFDLEGTTEIETPTAHSIVIKRQ
                     NKDKSVTAVAEIDLQNQTYRVIENGVEVTF"
     gene            9158..10351
                     /locus_tag="VYO11_001598"
     CDS             9158..10351
                     /locus_tag="VYO11_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008293041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HEV1596138.1"
                     /translation="MKSIGFIEKLKGLSSKELILLGIILSIFLPFYLFVVVLCLYIIS
                     LIFTGDMKSILQKMGEHPMLLLFLSYSTVISILAQNWMGLVASVGMFLFTIFFLHYQS
                     ILSHKFFRLILQFVLFGSVLSAAFASLEHFQIVKKFNYAFLSPNMQVWHQNRAEVTFF
                     NPNYYGIICCFCIMIAFYLFTTTKLNWLKVFCVIAGFVNLFGLNFTQNRTAFPAIIAG
                     AIIYLFTTIKNWKAFWLSIGVFAIGLSFLFSSDLGVRMGTLDSSMEERISIWDAGMAL
                     FKQNPFWGEGPLTYMHSYPRIHAPYHEHAHSLYIDTILSYGIVGTILLVLSSVAPVRL
                     MMDMSQESGKRPIIGLYLSFLTVVAVHGIFDLALFWIQSGFIFLLVMCSIPLEHRMLV
                     SDMTD"
     gene            11037..13016
                     /locus_tag="VYO11_001599"
     CDS             11037..13016
                     /locus_tag="VYO11_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000742236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV1596139.1"
                     /translation="MKKNRVFATAGLVLLAAGVLAACSSSKSSDSSAPKAYGYVYTAD
                     PETLDYLISSKNSTTVVTSNGIDGLFTNDNYGNLAPAVAEDWEVSKDGLTYTYKIRKG
                     VKWFTSDGEEYAEVTAKDFVNGLKHAADKKSEAMYLAENSVKGLADYLSGTSTDFSTV
                     GVKAVDDYTLQYTLNQPEPFWNSKLTYSIFWPLNEEFETSKGSDFAKPTDPTSLLYNG
                     PFLLKGLTAKSSVEFVKNEQYWDKENVHLDTINLAYYDGSDQESLERNFTSGAYSYAR
                     LYPTSSNYSKVAEEYKDNIYYTQSGSGIAGLGVNIDRQSYNYTSKTTDSEKVATKKAL
                     LNKDFRQALNFALDRSAYSAQINGKDGAALAVRNLFVKPDFVSAGEKTFGDLVAAQLP
                     AYGDEWKGVNLADGQDGLFNADKAKAEFAKAKKALEADGVQFPIHLDVPVDQASKNYI
                     SRIQSFKQSVETVLGVENVVVDIQQMTSDEFLNITYYAANASSEDWDVSGGVSWGPDY
                     QDPSTYLDILKTTSSETTKTYLGFDNPNSPSVVQVGLKEYDKLVDEAARETSDLNVRY
                     EKYAAAQAWLTDSSLFIPAMASSGAAPVLSRIVPFTGASAQTGSKGSDVYFKYLKLQD
                     KVVTKEEYEKAREKWLKEKAESNEKAQKELASHVK"
     gene            13083..14579
                     /locus_tag="VYO11_001600"
     CDS             13083..14579
                     /locus_tag="VYO11_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1596140.1"
                     /translation="MKKYIFMRVLRSLVSIFLVTTLTYTIIYTLVPRKLIFKQDPNYN
                     KIATTADKRDNYENTVFERMGYIEYYDTKELQEKASSMDSSVTVEANATNKAIYEKYI
                     NQLGHGWTLGEFTESGQFYATREIPIFERVFHFYANLIDIDHTNKIQDPENPDLKRYL
                     RFENDPAIGWSLVGSGTKHKYLLYFNSQFPFVHQNFVNLNLGDSYPTYANTPVLQVIT
                     QGQGQTKTAQVQFPTGKKTSSVNIYSRTYKSPSQADSREVASYGKDDPYTATESNYQY
                     PSMIVSSAITGLIGLVLAYALAVPLGSAMARFKNTWIDSLSTGTLTFLLALPTIALVY
                     IVRLIGSSIALPDSFPILGAGDWRSYVLPAVILGLLGAPVTAIWIRRYMIDLQSQDFV
                     RFARAKGLSEKEISNKHIFKNAMVPLVSGIPGAIIGVIGGATLTETVFAFPGMGKMLI
                     DSVKASNNSMVVGLVFIFTCISIFSRLLGDIWMTIIDPRIKLTEKGGK"
     gene            14579..15505
                     /locus_tag="VYO11_001601"
     CDS             14579..15505
                     /locus_tag="VYO11_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1596141.1"
                     /translation="MSTIDKEKFQFVKRDDFASETIDAPAYSYWKSVFKQFMKKKSTV
                     VMLGILVAIILISFIYPMFSKFDFNDVSKVNDFSVRYIKPNAEHWFGTDSNGKSLFDG
                     VWFGARNSILISVIATVINLVIGVFVGGIWGISKSVDRVMMEVYNVISNIPPLLIVIV
                     LTYSIGAGFWNLIFAMSVTTWIGIAFMIRVQILRYRDLEYNLASRTLGTPTLKIVAKN
                     IMPQLVSVIVTTMTQMLPSFISYEAFLSFFGLGLPITVPSLGRLISDYSQNVTTNAYL
                     FWIPLTTLVLVSLSLFVVGQNLADASDPRTHR"
     gene            15514..16581
                     /locus_tag="VYO11_001602"
     CDS             15514..16581
                     /locus_tag="VYO11_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1596142.1"
                     /translation="MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALV
                     GESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDLTALSSHKEWEQIRGAKIATIFQ
                     DPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
                     SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITH
                     DLGVVASIADKVAVMYAGEIVEYGTVEEVFYDPRHPYTWSLLSSLPQLADDKGDLYSI
                     PGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSETHWAKTWLLHEDAPKVEKP
                     AVIANLHDKIREKMGFAHLAD"
     gene            16592..17518
                     /locus_tag="VYO11_001603"
     CDS             16592..17518
                     /locus_tag="VYO11_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1596143.1"
                     /translation="MSEKLVEIKDLEISFGEGSKKFVAVKNANFFINKGETFSLVGES
                     GSGKTTIGRAIIGLNDTSNGDIIFDGQKINGKKSREQAAELIRRIQMIFQDPAASLNE
                     RATVDYIISEGLYNHRLFKDEEERKEKVQNIIREVGLLAEHLTRYPHEFSGGQRQRIG
                     IARALVMQPDFVIADEPISALDVSVRAQVLNLLKKFQKELGLTYLFIAHDLSVVRFIS
                     DRIAVIYKGVIVEVAETEELFNNPIHPYTQALLSAVPIPDPILERKKVLKVYDPSQHD
                     YETDKPSMVEIRPGHYVWANQTELARYQKGLN"
BASE COUNT         5168 a         3123 c         3679 g         5587 t
ORIGIN      
        1 gttttaatga gagtttgtaa ctctcttttt tgtttttaga gacaataaaa cttcagatcc
       61 gtaaaactta attgaattac taatctgaag ttatttttat atcgtttata ttataattgt
      121 gttattttac ttccaactat tgagagaaat ttcgccacta tttagccaga tttcttttcc
      181 gttatcacat tgaactaaaa gttttccatt ttctgagatg tctttagcaa atcccttgta
      241 gtctttttgc tctagtgtga aagtgacttc ttttcctaga atgaatgact gttttttgta
      301 taggtataat agctcttctg ctggtgtttc gaagaaagta cgccagattt ctatgatcaa
      361 ttcattcctt gttataggag ctgtagcttt aaataagctg ccagcttttt cttttaattc
      421 ctgagggaag tctttaatag tgaaattgat acctactcca ataatgatat ctgtgactaa
      481 gccagtttct acagaggtca ttgcttcagt aaggattcct ccaattttat gattgtttag
      541 atagatatca ttgacccatt ttatgtcgac atctattaaa gttaggttct taatggcttt
      601 gtagacagct ccagctacaa gtagtgtgta ggatggtaat ttgtcatagg ggagatttgg
      661 tttaagatgg agtgtcatat aaataccacc ttgtggtgag tagaaggaac gttgaaaacg
      721 gcctcggcct gctgtttgat aggaagctag atagagggta tttgcttcat ggcctaaatc
      781 aattgcttct tttgcatcta gttgtgttga ttttgtttcg ggtttaaagc tgactttaat
      841 tggaagattt tcttctagaa tctctggaag aataaggtca ccattcatca gtttatatcc
      901 tctatttttg atactatcaa tttcaatgcc ttcttgttct agtcgcttga tggctttcca
      961 aattgatgtt cggcttaggg atagtttttc tgcgattttt tctccgctga tatagtcggt
     1021 ttctttagat aggatttggt agacagcttg gtaggatttc ataatgttgc ctttcttact
     1081 agttggtatt gagagtattc ttttcttgta tgacttggag tctgattaaa gtattgttta
     1141 taagctttcg aaaaatggag tggatctgaa aaacctaccg agtatgcaat taccttgatg
     1201 gactcttggg tattttcgag aagttgtcta gctcggtgca ttcgaacgta gagtaggtat
     1261 tctttgggtg ataaggtatt aaattctttg aatacgcttg ataagtagct tctgtgaacg
     1321 gatagttctt ttgctaaatc ttgaattgta agtgattgag gatagtggct atcaattaat
     1381 cgtttgcatt caagatagag ttggtgggtt gatgaaatat tctttttttt ctgattggga
     1441 gcaatagttc ccagatgaaa catcagttca tgaagttgtc ccatgatatg gagttgagct
     1501 aattcacttg attttgtaat ctgagcgaag cggacaatgt ctgagatgag ttttgcagta
     1561 gtctgggtat gacaagtttc agattggatg agataggatt gatcagaaat ttgagaaaga
     1621 gcaaaataat caggggattt ccctccagtg attcctaacc agtagtaggc ccaaggttct
     1681 ttactatctg cttgataaaa ggttagttcc tctggtttta atagaaagaa atctccttct
     1741 tttaaatcaa caattttacc cttgtaatga aattttcctt gtcctttagt aatgtaatgt
     1801 aggacgtatg tatcacgaat ggctggacca aaagagtaat taggtgtgca ttcctcatat
     1861 ccataaaagc ttagggcaag gtcgattgtt ccagtctggt attctgaaaa aactaacatg
     1921 tgctacctcc tacctaacat tttaccatat tcttgagaca tttttctatt ttagaaagcg
     1981 atttcaggtg ataaaatata atcaataaag tgatgaggtg aagtaaatgg gagttaggat
     2041 agagaataat ctattttatg ttgagagtaa aaatctaagt ttgattattg aaaatcgaaa
     2101 tggctactta cttttgaaac atttaggaaa gactattaag aactataaag gttccaatag
     2161 tgtttatgaa cgagaccatg ccttttcagg aaatccaaca gctactaatc gaacctttag
     2221 tttagatact caacgtcaaa tttttggaca acatggctta ggagatttta ggaaaccaac
     2281 catacaggtt cagcataatg taactgaagt aacagacttt cgatttgtag aagcaaagat
     2341 tttaaaaggt cagaatggtc cacagggctt accttctcca catagcatgg acgatacaga
     2401 gactcttgtc ttaatgttag aagattctaa ggctcaactt agtctgactt tgtattatac
     2461 tacttttaat aatgatgcga ctattgctag ctacagtaaa ttagataata atagtaatca
     2521 ggaagttgtc atctataaag atttttcttt tatggctgat tttccagctg cagattacga
     2581 aatagtaact ctgcagggtg cttatgctcg tgaaaagact gttagacgtc aacaggtaga
     2641 acaaggaatc ttttcgatta gttcaaaccg aggtgcttct ggtcatgctc aaacaccagc
     2701 tcttctacta tgcgaacaag gagtcacaga ggatgctggg aatgtgtttg ctattcaact
     2761 aatgtatagt ggcaactttg aagcttttgt tcaaaaaaat caattgaatg aagttcgggt
     2821 ggctattggc attaatccag aaaacttttc ttggaagtta gcccctgagg aatactttga
     2881 aacaccggta gctttagtga ctcattcaga tcagggatta actggtatta gtcatgaaag
     2941 tcagaatttt gtactggagc acattatgct aagtgaattt tctaaaaaag aacgtccaat
     3001 tctaatcaat aactgggaag ctacttactt tgactttcag agagaaaaac tgttagagtt
     3061 agcagatgaa gctaagaaag ttggcattga actttttgta ttagatgatg gttggtttgg
     3121 caatcgtttt gatgataatc gtgctttagg tgattgggtt gttaatgagg aaaaactggg
     3181 tggaagtcta gaaagtctga tttcagctat ccatgaaaga ggtttgcagt ttggactttg
     3241 gttagaaccc gaaatgattt ctgtagatag tgatttgtat cgtcaacatc ctgactgggc
     3301 tattcaggtt cctggctatg agcatactta ttctcggaat caattagtac ttaatcttgc
     3361 caatcctcag gtagtagaat acttgaaaag tgtcttagat caattcctat cttatcatga
     3421 tattgattac attaaatggg atatgaaccg caatatcact aagctaggga atggattaac
     3481 ttatctagag acacagatgc aatctcatca gtacatgctg gggctttacg aactcgtttc
     3541 ttatctgaca gagaagcaca gccatattct ctttgagtcc tgctctggtg gtggtggacg
     3601 aaatgatctt ggtatgatgc gctatttccc acaagtctgg gctagtgata atactgatgc
     3661 cattgcacgt ttaccaattc aatacggttc atcctatctc tatccaacca tttctatggg
     3721 ggctcatgtg tcagcagtac cgaatcatca gatgggacga atgacaccat tagaaacacg
     3781 tggccttgta gcaatgatgg gaaatttggg ctatgaactt gatttgacaa atttatcaga
     3841 tgaagagaaa gctacgattg ctaatcaggt gaacttgtat aaagaattac gaccagtagt
     3901 tcagttagga cagcagtata gactaattaa tcctgatact gtatccaatg aagcagctgt
     3961 acaatttaat tacggaaatc aaacgattgt aacctacgtt cgcgttttat ctgttgtaga
     4021 gaccatggaa acaactttaa aattaaaaaa tttggatgaa gagggactat ataaattaca
     4081 ggaaaatggc gaagtttact caggtgcaga actaatgtat gcgggcctaa ctgttatctt
     4141 atcccaagga gattttttga gtagacagta tatttttaga aaactatgat atgtactgac
     4201 ctcaaaagtt agatttattc tatctaactt ttgaggtgca gtttgataag ggtgtataaa
     4261 tttataaagg aggctttcta atggaatggt ataaaaaaat cggacttctt gcaactacag
     4321 gtttagcttt gtttgggctc ggtgcttgct ccaactatgg taaatctgcg gatgacacag
     4381 tgaccatcga gtatttcaac cagaaaaaag aaatgaccaa aaccttggaa gaaatcactc
     4441 gtgattttga gaaggaaaac cctaagataa aggtcaaagt cgtcaatgta ccaaatgctg
     4501 gtgaagtatt gaagacacgc gttctcgcag gagatgtgcc tgatgtggtc aatatttacc
     4561 cacagtccat cgaactgcaa gaatgggcaa aagcaggtgt ctttgaagat ttgagtaaca
     4621 aagactacct gaaacgcgtg aaaaatggct acgctgaaaa atatgctgta aacgaaaaag
     4681 tttacaacgt tccttttaca gctaatgctt atggaattta ctacaacaaa gataaattcg
     4741 aagaactggg cttgaaagtt cctgaaacct gggatgaatt tgaacagtta gtcaaagata
     4801 tcgttgctaa aggacaaaca ccatttggaa ttgcaggtgc agatgcttgg acactcaatg
     4861 gttacaatca attagccttt gcgacagcaa caggtggagg aaaagaagca aatcaatacc
     4921 ttcgttattc tcaaccaaat gccattaaat tgtcggatcc gattatgaaa gatgatatca
     4981 aggtcatgga catccttcgc atcaatggct ctaagcaaaa gaactgggaa ggtgctggct
     5041 ataccgatgt tatcggagcc ttcgcacgtg gggatgtcct catgacacca aatgggtctt
     5101 gggcgatcac agcgattaat gaacaaaaac cgaactttaa gattgggacc ttcatgattc
     5161 caggaaaaga aaaaggacaa agcttaaccg ttggtgcggg agacttggca tggtctatct
     5221 cagccaccac caaacatcca aaagaagcca atgcctttgt ggaatatatg acccgtccag
     5281 aagtcatgca aaaatactac gatgtggacg gatctccaac agcgatcgaa ggggtcaaac
     5341 aagcaggaga agattcaccg cttgctggta tgaccgaata tgcctttacg gatcgtcact
     5401 tggtctggtt gcaacaatac tggaccagtg aagcagactt ccataccttg accatgaact
     5461 atgtcttgac cggtgataaa caaggcatgg tcaatgattt gaatgccttc tttaacccga
     5521 tgaaagcgga tgtggattag gagtagagag actatgaaaa aagtattaca aaaatattgg
     5581 gcatgggctt ttgtggtcat ccccctcttg ttacaagcaa ttttcttcta tgtgccgatg
     5641 tttcaaggag ccttttacag ttttaccaac tggacaggat tgacttacaa ctacaaattt
     5701 gtcggcttaa acaactttaa gctcctcttc atggatccaa aattcatgaa tgcgattggc
     5761 tttaccgcaa tcattacgat tgccatggtg gttggtgaga ttgcactcgg gatcttcatt
     5821 gcgcgtgtct tgaactctaa aatcaaaggc caaaccttct tccgtgcttg gttcttcttc
     5881 ccagctgttt tatctggttt gacagtggct ttgatcttca agcaagtctt caactacggt
     5941 cttccagcga ttgggaatgc ccttcatatt gaatttctcc aaaccagtct tttagggact
     6001 aagtggggag caatctttgc ggctgtcttt gtccttcttt ggcaaggggt ggctatgccc
     6061 atcatcatct tcctagctgg tttgcaatct attccaactg agattacaga ggcagcaagg
     6121 attgatggtg cgactagcaa gcaagttttc tggaacattg aattgcctta cttgctacca
     6181 agtgtctcta tagtctttat cctagcccta aaaggtgggc tgactgcctt tgaccaagtc
     6241 tttgccatga ccggtggtgg tccaaacaat gccacaacct cacttgggct cttggtttat
     6301 aactatgcct ttaaaaacaa ccaattcggt tatgccaatg ccattgccgt aatcttgttc
     6361 ttcttaattg tagtgatttc gatcatccaa ttgagagtat ctaagaaatt tgaaatttaa
     6421 gaggagaagc atgatgaaac aagatgaaag aaaagccctg attggcaaat acattctatt
     6481 gattctagga tcggttctga ttttagtgcc gctccttgct accctcttta gttccttcaa
     6541 acccactaag gatattgtag ataatttctt tggctttcca accaacttca catgggacaa
     6601 ctttagccgt ctcttagctg atgggattgg aggctattat tggaactctg tcgtcatcac
     6661 tgtcttgtct ttacttgcag taatgatctt tatccctatg gcagcctact ccatcgctcg
     6721 caatatgagt aaaagaaaag cctttaccat catgtatacc ctcttaatcc tcggaatctt
     6781 cgtacctttc caagtcatca tgattccgat tacggttatg atgagtaaac tcggtttggc
     6841 taataccttt ggtttgatct tgctctactt gacctatgcg attccacaga ccctctttct
     6901 ctatgttggc tatatcaaaa tctcgattcc agaaagtctg gatgaagcag cagagatcga
     6961 tggggctaat caatttacaa cctatttccg catcatcttc ccaatgatga aaccgatgca
     7021 tgcgacaacc atgattatca atgccctttg gttctggaat gacttcatgt tgccactcct
     7081 tgtcttgaac cgggattcca aaatgtggac tctgcctttg ttccaataca actacgcagg
     7141 ccaatatttc aacgactacg gaccaagctt tgcctcttac gtggtcggca ttatcagtat
     7201 caccattgtc tatctcttct tccaacgcca tatcatttca ggaatgagca acggggcagt
     7261 gaagtaatac tcaatgaaaa tcaaagagca aactaggaag ctagccgcag gctgtacttg
     7321 agtacggtaa ggtgaagctg acgtggtttg aagagatttt cgaatagtat aagaagagct
     7381 catggaatct atagtctttg acacagagga agagttcagc ttgttgataa ttctatgtag
     7441 aaaacaagaa agtagtactt tgtttatcac agtctatatt agtacgagtt tgatgataaa
     7501 tagagattta aaatgaattt tatttatgaa gccagatcat atgagacttg gcttcaatta
     7561 gaaaaaggag agtaatgatg ccaattcaaa ataaaaccat gttgattacc tattctgata
     7621 gccttggaaa taatcttaaa gacttatatg ataatttgga agagcatttt ggagatgcta
     7681 ttggaggagt tcacctttta ccatttttcc catcaacagg tgatcgtgga tttgcgccag
     7741 ttgactacga cgaagtggac tcagcttttg gtgattggga ggatgttaag cgtttaggtg
     7801 agagatatta tcttatgttt gattttatga ttaatcatat ttctcgtcaa tccaagtatt
     7861 ataaggacta tcaagaaaaa catgaagcca gtgaatttaa agatctcttt ttaaactggg
     7921 ataagttttg gccagaaaac cgtccgacac agtctgatgt agatttaatt tacaagcgta
     7981 aggatcgtgc accaaagcaa gagattgtgt ttgaagatgg ttcagtggaa catttgtgga
     8041 atacctttgg tgaggagcag attgatcttg atgtgaccaa agaagtaact atggaattta
     8101 tccgtaagac cattcagcac ttggcaagta atgggtgtga tttgattcgt ctagatgcct
     8161 ttgcttatgc agtgaagaaa ttggatacta atgatttctt tgtggaacca gatatttggg
     8221 atttattgga caaagttcga gatatcgctg ctgagtatgg gacagagctt ttacctgaga
     8281 ttcatgaaca ctattcgatt cagtttaaaa tagcagacca tgattactat gtttatgatt
     8341 ttgctcttcc aatggtgaca ctttatactc tttacagttc cagaacagag cgtttggcta
     8401 agtggttaaa gatgagcccg atgaagcaat ttacgacgct agatacccat gatgggattg
     8461 gagtagtaga tgtcaaggat atcctgaccg atgaggagat tgactatgct tcaaatgaac
     8521 tctataaggt tggagccaat gtcaaacgta agtactctag tgccgagtat aacaacttag
     8581 atatctacca aatcaattca acctactatt cagcgcttgg agatgatgat gtcaagtatt
     8641 ttctcgctcg tctaattcaa gcttttgccc caggtattcc tcaggtttac tatgtgggtc
     8701 tattagcagg caagaatgac ttgaaattat tagaagaaac taaagaaggt cgaaatatta
     8761 atcgtcatta ctatagcaac gaggaaatag caaaagaagt gcaacgacct gttgtgaagg
     8821 cccttctcaa tctattttct ttccgtaacc gttcagaagc ctttgatcta gaagggacta
     8881 ctgagataga gacaccaaca gctcacagca ttgtaatcaa acgtcaaaat aaagataagt
     8941 ccgtaacagc agtagcagaa attgatttgc aaaatcagac ttatcgggta attgagaatg
     9001 gagttgaagt aacattttga agccttgata tggtggataa aatagggttt ttattttgga
     9061 aaacgtttcc tttgttttca aattgctaaa aaagtggtac aatataggat agcttactat
     9121 tatctgaatc agctgatttg gagagaaagg attcattttg aaatcaatag gctttattga
     9181 aaagctgaag gggttgtcta gtaaagagct gattttattg ggaattatcc taagtatctt
     9241 tttacccttt tatctttttg tagttgtact ctgtttatat attatcagtt tgatttttac
     9301 aggagacatg aaaagtattc ttcagaaaat gggggagcat ccgatgctgc ttctttttct
     9361 tagctatagt actgttatat ccattcttgc acaaaattgg atgggtcttg tggcttcagt
     9421 aggaatgttt ctatttacta ttttcttttt gcactatcag tcgattttat cccataaatt
     9481 ctttcgattg attttgcagt tcgtcttgtt tggtagtgtc ttgtcagctg cttttgccag
     9541 tttagaacat ttccaaattg tgaagaaatt taactatgct tttctttcac ccaatatgca
     9601 ggtgtggcat cagaaccggg cagaagtgac cttctttaat cctaattatt atggaattat
     9661 ttgttgtttc tgtattatga ttgctttcta tctgtttaca acgaccaagt tgaattggtt
     9721 gaaagtattc tgtgtgattg caggctttgt taatctcttt ggtttgaact ttactcaaaa
     9781 tcgaactgcc tttcctgcta ttatcgctgg agcaattatc tatctcttta cgactattaa
     9841 aaactggaag gccttttggc ttagtattgg ggtcttcgcg attggtttga gtttcctctt
     9901 ttctagtgat ttgggagttc gaatgggtac tttagactct tctatggaag aacgcatttc
     9961 tatctgggat gctgggatgg ccttgtttaa gcaaaatcct ttttggggtg aagggccatt
    10021 gacctatatg cactcttatc ctcggataca tgctccttat catgaacatg cccacagtct
    10081 ttatattgat acgattctga gttacggaat tgtgggtacc attttattag ttctgtcttc
    10141 tgttgctcct gttcgcttga tgatggatat gagtcaggag tcggggaaac gtccgattat
    10201 cggcctttat ctatctttcc ttacagtggt tgctgtgcac ggaatttttg acttggctct
    10261 cttctggatt cagtcaggct ttattttctt gctagttatg tgcagtattc cattggagca
    10321 tcgaatgttg gtatcggaca tgacggatta agttttataa gtttgaaatc ttctaccttg
    10381 ggtaggagat tttttatacg atgggcatgt cgtggatctg aggtgtaagt cctctgtagg
    10441 gatccactac cggtgaatac aatagcgctc cccaagcctg actatcgtga ggtagcggat
    10501 taaaatggtc tggggataga tcgttttaag tctgacgcag gaaataagaa ttgtcagaga
    10561 aagcaatagt gaaatcgtag gctatgaata gaaacgtgat agcgaggagc atatagtgga
    10621 caaggtagcg agaaatttta aagtataaaa gatagtctta atctatatgt gtaaatcacg
    10681 aaagtaattg aattcggaat aaggttggtg tgaaaagaca tagtaaactg aatcttgaat
    10741 actagaatga tacttctaca atattgttat aatttaattt gaattccaaa atcacattgt
    10801 tccgtccgta tttcatttta ctgtatgtct tcctaagctc caaaatttct gtgtcaaatt
    10861 tcctattttc actgtagtct ttgacacttc gaacgacaat ttgaatcata tattcaaaaa
    10921 aaaatgaaaa atttgtgcca acaagcctaa atattctgaa aatttgtttg atttttaatg
    10981 gataatgtga tataatggtt gtcaatctat aattcacata aacagaggag tagaaaatga
    11041 aaaaaaatcg tgtatttgct acagcaggtc ttgttttatt agcagcaggt gtacttgcag
    11101 catgcagttc ttcaaaatca tctgattcat cagcccctaa agcttatggc tatgtttata
    11161 cagcagaccc agaaaccttg gactacctga tttcaagtaa aaatagtaca acagtagtga
    11221 cttcaaatgg gattgatggt ttattcacta acgataatta cggtaatctt gctcctgcag
    11281 ttgcagagga ttgggaagtc tctaaggatg gtttgaccta cacttataag attcgtaaag
    11341 gggttaaatg gtttacctct gatggagaag aatatgcaga ggtgacggct aaagatttcg
    11401 tgaacggttt aaaacacgca gcagataaaa aatcagaagc tatgtattta gctgaaaatt
    11461 cggttaaagg cttggcagat tatctatcag gaacttcaac agatttttca acagttggtg
    11521 tcaaggcggt tgatgattat acgttacaat acactttgaa ccagcctgaa ccgttctgga
    11581 actctaagtt gacctattct attttctggc ctctgaatga agaattcgaa acatcaaaag
    11641 gaagcgattt tgctaaacca acagatccga catccttgct ttataatggt ccattcttgt
    11701 tgaaagggtt gactgcaaaa tcttctgtag agtttgtaaa aaatgagcaa tattgggata
    11761 aagaaaatgt ccacctagat actatcaatc tagcttacta tgatggatca gatcaggagt
    11821 cgctagagcg taacttcact agtggagctt atagttatgc ccgtctttac cctaccagct
    11881 ccaactattc taaggttgca gaagaataca aggacaatat ctattacaca caatcaggct
    11941 ctgggattgc tggtctgggt gtgaatattg atcgccaaag ttacaactat acctctaaaa
    12001 ctacagattc agagaaagta gctactaaga aggcattgct taacaaagat ttccgtcaag
    12061 ccttgaattt tgctcttgat cgctcagctt actcagctca aatcaatggt aaagatggag
    12121 cagctttagc agttcgtaat ttatttgtaa aaccagactt tgtttcagct ggtgagaaga
    12181 cctttggtga tttagtcgct gctcaacttc ctgcttatgg tgatgagtgg aaaggtgtga
    12241 atttagctga tgggcaggat ggtttattca atgctgacaa ggccaaggca gagtttgcga
    12301 aagctaagaa agctttagaa gcagacggcg ttcagtttcc tattcatctg gacgttccag
    12361 tagaccaagc atcaaaaaac tacatatctc gtattcagtc ttttaaacaa tctgtagaaa
    12421 cagttcttgg tgttgaaaat gtcgttgttg atattcaaca aatgacaagt gatgaattcc
    12481 ttaatattac ttactatgct gccaatgctt catctgagga ttgggatgta tcaggaggag
    12541 tttcatgggg tccagactat caagacccat ctacttacct ggatatttta aaaacaacta
    12601 gcagtgaaac tacaaaaaca tatttaggat ttgataatcc aaatagccct tcagtagttc
    12661 aagttggttt gaaagaatac gataaattag ttgatgaagc tgccagagag acaagcgact
    12721 tgaatgtccg ttatgaaaaa tatgcagcgg ctcaagcatg gttgacagat agttcactct
    12781 ttattcctgc tatggcttct tctggtgcag caccagtgct ttcacgaatt gttccattta
    12841 ctggagcttc tgcgcaaaca ggctctaagg ggtcagatgt ttacttcaaa tatttgaaat
    12901 tacaagataa agtggtgact aaggaagagt atgaaaaagc tcgtgaaaaa tggttgaaag
    12961 aaaaagctga atcaaatgag aaagctcaaa aagaattggc aagtcatgtg aagtaaataa
    13021 tttctaatag aactttctct ccatgaggag aaggttcttt tgggattttt aaaggaaata
    13081 atatgaaaaa atatattttt atgcgtgttt tgcggtcatt ggtttcgatt ttcttagtaa
    13141 cgactttgac ctacacgatt atctatacct tggttcctcg aaaattgatt ttcaagcagg
    13201 atcctaacta taataaaatt gcgacaacgg ctgataaacg tgataactat gaaaatactg
    13261 tgtttgagcg tatgggctac attgagtatt acgatactaa agagttgcaa gaaaaggcaa
    13321 gtagcatgga ttcttctgta acagtagaag caaatgcgac caataaagct atttatgaaa
    13381 agtacatcaa tcaattaggt catggttgga ctttgggaga atttactgaa agtggtcaat
    13441 tctatgctac tcgtgaaatt ccaatttttg aacgtgtttt tcacttctat gctaacttga
    13501 ttgacattga ccatacaaat aaaatccaag accctgaaaa tccagacttg aaacgctacc
    13561 ttcgttttga aaatgatcca gctatcggat ggtcattggt cggttcagga actaaacata
    13621 aatatctctt gtactttaac agtcagttcc catttgttca tcaaaacttt gtgaacttga
    13681 atttaggtga ctcttaccca acctatgcta atacaccagt tcttcaggtt attactcaag
    13741 gtcaaggaca aaccaaaact gcccaagttc agttcccaac aggtaagaaa acgtcttctg
    13801 taaatattta ctcaagaacc tacaagtcac ctagtcaggc tgactctcgt gaagtagcta
    13861 gctatgggaa agatgatcct tatacagcga ctgaaagtaa ttaccaatat ccatctatga
    13921 ttgtcagctc tgctattact ggtttgattg gtttggttct tgcctatgct cttgccgtgc
    13981 cacttggttc agccatggct cgtttcaaga acacttggat tgatagcctc tcaacaggga
    14041 ctttgacctt cttgcttgct cttccaacga ttgccttggt ttacatcgtt cgattgattg
    14101 gatcatctat tgcccttcca gattcattcc ctatcttggg agctggagat tggcgttctt
    14161 acgttttacc agcagtcatc cttggtttgt tgggtgctcc tgttacagcc atttggattc
    14221 gtcgttacat gattgacttg caatctcaag actttgttcg tttcgctcgt gcaaaaggtt
    14281 tgtctgaaaa agaaatttca aacaaacaca tctttaaaaa tgccatggtt ccgctggttt
    14341 caggaattcc tggtgccatt attggggtta tcggtggtgc aacccttact gaaacagtct
    14401 tcgccttccc aggtatgggt aaaatgttga ttgactctgt aaaagcatct aataactcta
    14461 tggtcgttgg tcttgtcttc atctttacat gtatttctat cttctcacgt cttttgggag
    14521 atatttggat gactattatt gacccacgta ttaaattgac tgagaaagga ggcaaataat
    14581 gtctacaatc gataaagaaa aatttcagtt tgtaaaacgt gacgattttg cctctgaaac
    14641 tattgatgcg ccagcatatt cttactggaa atcagtgttt aaacaattta tgaagaaaaa
    14701 atcaactgta gtcatgttgg gaatcttggt agccatcatt ttgataagtt tcatctaccc
    14761 aatgttttct aagtttgatt tcaatgatgt cagcaaggta aacgacttta gtgttcgtta
    14821 tatcaagcca aatgcggagc attggttcgg tactgacagt aacggtaaat cgctctttga
    14881 cggtgtctgg ttcggagctc gtaactccat cctcatttct gtgattgcga cagtgattaa
    14941 cttggttatc ggtgtttttg tcggtggtat ttggggtatt tcaaaatcag ttgaccgtgt
    15001 catgatggaa gtttacaacg tcatctcaaa catcccacct cttttgattg ttattgtctt
    15061 gacttactca atcggagctg gattctggaa tctgattttt gccatgagcg taacaacatg
    15121 gattggtatt gccttcatga tccgtgtgca aatcttgcgc tatcgtgact tggaatacaa
    15181 cttggcgtca cgtactttgg gaacaccaac cttgaagatt gttgccaaaa atatcatgcc
    15241 tcaattggta tctgttattg tgacaaccat gactcaaatg cttccaagct ttatctcata
    15301 cgaagccttc ttgtctttct tcggtcttgg attaccgatt acagtgccaa gtttgggtcg
    15361 tttgatttcg gattattcac aaaacgtaac aaccaatgct tacttgttct ggattccatt
    15421 gacaaccctt gtcttggtat ccttgtccct tttcgtagtt ggtcaaaact tagcggatgc
    15481 tagtgatcca cgtacacata gataggagta gaaatgacaa aagaaaaaaa tgtaattttg
    15541 actgctcgcg atattgtcgt ggaatttgac gttcgtgaca aagtattgac agccattcgc
    15601 ggcgtttccc ttgaactagt tgaaggagaa gtattagcct tggtaggtga gtcaggatca
    15661 ggtaaatctg ttttgacaaa gaccttcaca ggtatgctcg aagaaaatgg tcgtattgcc
    15721 caaggtagta ttgactaccg tggtcaggac ttgacagctt tatcttctca caaggagtgg
    15781 gaacaaattc gtggtgctaa gattgcgact atcttccagg acccaatgac tagtttggac
    15841 cccattaaaa caattggtag tcagattaca gaagttattg taaaacacca aggaaaaaca
    15901 gctaaagaag cgaaagaatt ggccattgac tacatgaata aggttggcat tccagacgca
    15961 gatagacgtt ttaatgaata cccattccaa tattctggag gaatgcgtca acgtatcgtt
    16021 attgcgattg cccttgcctg ccgacctgat gtcttgatct gtgatgagcc aacaactgcc
    16081 ttggatgtaa ctattcaagc tcagattatt gatttgctaa aatctttaca aaacgagtat
    16141 catttcacaa caatctttat tacccacgac cttggtgtgg tggcaagtat tgcggataag
    16201 gtagcggtta tgtatgcagg agaaatcgtt gagtatggaa cggttgagga agtcttctat
    16261 gaccctcgcc atccatatac atggagtctc ttgtctagct tgcctcagct tgctgatgat
    16321 aaaggggatc tttactcaat cccaggaaca cctccgtcac tttatactga cctgaaaggg
    16381 gatgcttttg ccttgcgttc tgactacgca atgcagattg acttcgaaca aaaagctcct
    16441 caattctcag tatcagagac acattgggct aaaacttggc ttcttcatga ggatgctcca
    16501 aaagtagaaa aaccagctgt gattgcaaat ctccatgata agatccgtga aaaaatggga
    16561 tttgcccatc tggctgacta ggaggaagga aatgtctgaa aaattagtag aaatcaaaga
    16621 tttagaaatt tccttcggtg aaggaagtaa gaagtttgtc gcggttaaaa atgctaactt
    16681 ctttatcaac aagggagaaa ctttctcgct tgtaggtgag tccggtagtg ggaaaacaac
    16741 tattggtcgt gctatcatcg gtctaaatga tacaagtaat ggagatatca tttttgatgg
    16801 tcaaaagatt aatggtaaga aatcgcgtga acaagctgcg gaattgattc gtcgaatcca
    16861 gatgattttc caagaccctg ccgcaagttt gaatgaacgt gcgactgttg attatattat
    16921 ttctgaaggt ctttacaatc accgtttatt taaggatgaa gaagaacgta aagagaaagt
    16981 tcaaaatatt atccgtgaag taggtcttct tgctgagcac ttgactcgtt accctcatga
    17041 attctcaggc ggtcaacgtc aacgtatcgg tattgcccgt gccttggtca tgcaaccaga
    17101 ctttgttatt gcagatgagc caatttcagc cttggacgtt tctgtacgtg cccaagtctt
    17161 gaacttgctc aaaaaattcc aaaaagagct cggcctgacc tatctcttca tcgcccatga
    17221 cttgtcggtt gttcgcttta tttcagatcg tatcgcagtt atttacaagg gtgttattgt
    17281 agaggttgca gaaacagaag aattgtttaa caatccaatt cacccatata ctcaagcctt
    17341 gctttcagcg gtaccaatcc cagatccaat cttggaacgt aagaaggtct tgaaggttta
    17401 cgacccaagt caacacgact atgagactga taagccgtct atggtagaaa tccgtccagg
    17461 tcactatgtt tgggcgaacc aaaccgaatt ggcacgttat caaaaaggac taaactagta
    17521 atggttttat aatttccatg tcaattttta tggaaat
//
LOCUS       DAVLXH010000045        17162 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00028199
            SAMN33607166-rid17955573.denovo.045, whole genome shotgun sequence.
ACCESSION   DAVLXH010000045 DAVLXH010000000
VERSION     DAVLXH010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607166
            Sequence Read Archive: SRR23725544
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17162)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17162)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721421.1
            Genome Coverage       :: 115x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:42:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,210
            CDSs (total)                      :: 2,161
            Genes (coding)                    :: 2,023
            CDSs (with protein)               :: 2,023
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 73 of 138
            Pseudo Genes (incomplete)         :: 60 of 138
            Pseudo Genes (internal stop)      :: 40 of 138
            Pseudo Genes (multiple problems)  :: 31 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17162
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607166-rid17955573.denovo.045"
                     /strain="AUSMDU00028199"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1349"
     gene            63..537
                     /locus_tag="VYO11_001604"
                     /pseudo
     CDS             63..537
                     /locus_tag="VYO11_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730798.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Type 1 glutamine amidotransferase-like
                     domain-containing protein"
     gene            819..1066
                     /locus_tag="VYO11_001605"
                     /pseudo
     CDS             819..1066
                     /locus_tag="VYO11_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000335280.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside phosphotransferase"
     gene            1171..1473
                     /locus_tag="VYO11_001606"
                     /pseudo
     CDS             1171..1473
                     /locus_tag="VYO11_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            1629..2858
                     /locus_tag="VYO11_001607"
     CDS             1629..2858
                     /locus_tag="VYO11_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HEV1596144.1"
                     /translation="MKISKRHLLNYSILIPYLLLSILGLIVVYSTTSAILIEEGKSAL
                     QLVRNQGIFWIVSLILIALIYKLRLDFLRNERLIILVILIEMLLLFLARFIGISVNGA
                     YGWISVAGVTIQPAEYLKIIIIWYLAHRFSKQQEEIATYDFQVLTQNQWLPRAFNDWR
                     FVLLVLIGSLGIFPDLGNATILVLVSLIMYTVSGIAYRWFSTILALVSATSVFVLTTI
                     SLIGVETFSKIPVFGYVAKRFSAFFNPFADRADAGHQLANSYFAMVNGGWFGLGLGNS
                     IEKRGYLPEAHTDFVFSIVIEEFGFVGASLILALLFFMILRIILVGIRAENPFNAMVA
                     LGVGGMMLVQVFVNIGGISGLIPSTGVTFPFLSQGGNSLLVLSVAVAFVLNIDASEKR
                     AKLYRELENQPMNLLLK"
     gene            2878..5574
                     /gene="ppc"
                     /locus_tag="VYO11_001608"
     CDS             2878..5574
                     /gene="ppc"
                     /locus_tag="VYO11_001608"
                     /EC_number="4.1.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxylase"
                     /protein_id="HEV1596145.1"
                     /translation="MSLQKLENSSNKSVVQEEVLILTELLEDITKNMLAPETFEKIIQ
                     LKELSTQEDYQGLNRLVTSLSNDEMVYISRYFSILPLLINISEDVDLAYEINHQNNID
                     QDYLGKLSTTIKLVAEKENAVDILEHLNVVPVLTAHPTQVQRKSMLDLTNHIHSLLRK
                     YRDVKLGLINKDKWYNDLRRYIEIIMQTDMIREKKLKVTNEITNAMEYYNSSFLKAVP
                     HLTTEYKRLAQAHGLNLKQAKPITMGMWIGGDRDGNPFVTAKTLKQSALTQCEVIMNY
                     YDKKIYQLYREFSLSTSIVNVSKQVREMARQSKDNSIYREKELYRRALFDIQSKIQAT
                     KTYLIEDEEVGTRYETANDFYKDLIAIRDSLLENKGESLISGDFVELLQAVEIFGFYL
                     ASIDMRQDSSVYEACVAELLKSAGIHSRYSELSEEEKCDLLLKELEEDPRILSATHAE
                     KSELLAKELAIFKTARVLKDKLGDDVIRQTIISHATSLSDMLELAILLKEVGLVDTER
                     ARVQIVPLFETIEDLDHSEETMRKYLSLSLAKKWIDSRNNYQEIMLGYSDSNKDGGYL
                     SSCWTLYKAQQQLTAIGDEFGVKVTFFHGRGGTVGRGGGPTYEAITSQPLKSIKDRIR
                     LTEQGEVIGNKYGNKDAAYYNLEMLVSAAINRMITQKKSDTNTPNRYEAIMDQVVDRS
                     YDVYRDLVFGNEHFYDYFFESSPIKAISSFNIGSRPAARKTITEIGGLRAIPWVFSWS
                     QSRVMFPGWYGVGSSFKEFINKNPENIAILRDMYQNWPFFQSLLSNVDMVLSKSNMNI
                     AFEYAKLCEDEQVKAIYEIILNEWQVTKNVILAIEGHDELLADNPYLKASLDYRMPYF
                     NILNYIQLELIKRQRRGELSSDQERLIHITINGIATGLRNSG"
     misc_binding    5657..5873
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            5986..6990
                     /locus_tag="VYO11_001609"
     CDS             5986..6990
                     /locus_tag="VYO11_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEV1596146.1"
                     /translation="MKNKRLIGIIAALAVLVAGSLIYSSMNKSEAQNNKDEKKITKIG
                     VLQFVSHPSLDLIYKGIQDGLAEEGYKDDQVKIDFMNSEGDQSKVATMSKQLVANGND
                     LVVGIATPAAQGLASATKDLPVIMAAITDPIGANLVKDLKKPGGNVTGVSDHNPAQQQ
                     VELIKALTPNVKTIGALYSSSEDNSKTQVEEFKAYAEKAGLTVETFAVPSTNEIASTV
                     TVMTSKVDAIWVPIDNTIASGFPTVVSSNQSSKKPIYPSATAMVEVGGLASVVIDQHD
                     LGVATGKMIVQVLKGAKPADTPVNVFSTGKSVINKKIAQELGITIPESVLKEAGQVIE
                     "
     gene            7059..7925
                     /locus_tag="VYO11_001610"
     CDS             7059..7925
                     /locus_tag="VYO11_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1596147.1"
                     /translation="MIVSIISQGFVWAILGLGIFMTFRILNFPDMTTEGSFPLGGAVA
                     VTLITKGVNPFLATLVAVGAGCLAGMAAGLLYTKGKIPTLLSGILVMTSCHSIMLLIM
                     GRANLGLLGTKQIQDVLPFDSDLNQLLTGLIFVSIVIALMLFFLDTKLGQAYIATGDN
                     PDMARSFGIHTGRMELMGLVLSNGVIALAGALIAQQEGYADVSRGIGVIVVGLASLII
                     GEVIFKSLSLAERLVTIVVGSIAYQFLVWAVIALGFNTSYLRLYSALILAVCLMIPTF
                     KQTILKGAKLSK"
     gene            7922..8680
                     /locus_tag="VYO11_001611"
     CDS             7922..8680
                     /locus_tag="VYO11_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1596148.1"
                     /translation="MTAIVELKNATKIVKNGFDEEKIILNDVSLKIFERDFITILGGN
                     GAGKSTLFNTIAGTLSLTSGTIRILGEDLTKFSPEKRAKYLSRVFQDPKMGTAPRMTV
                     AENLLIAKFRGEKRGLLPRRLTSYKDEFQATIEKVGNGLEKHLNTPIEFLSGGQRQAL
                     SLLMATLKRPELLLLDEHTAALDPKTSVALMELTDEFVKKDQLTALMITHHMEDALKY
                     GNRLIVMKEGRVIQDLKQEEKAKMKISDYYQLFE"
     gene            8770..10530
                     /gene="dnaG"
                     /locus_tag="VYO11_001612"
     CDS             8770..10530
                     /gene="dnaG"
                     /locus_tag="VYO11_001612"
                     /EC_number="2.7.7.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000227865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HEV1596149.1"
                     /translation="MVDKQVIEEIKNNANIVEVIGDVISLQKAGRNYLGLCPFHGEKT
                     PSFNVVEDKQFYHCFGCGRSGDVFKFIEEYQGVTFMEAVQILGQRVGIEVEKPLYSEQ
                     KPASPYQALYDMHEDAAKFYHAILMTTTMGEEARNYLYQRGLTDEVLKHFWIGLAPPE
                     RNYLYQRLSDQYREEDLLDSGLFYLSDANQFVDTFHNRIMFPLTNDQGKVIAFSGRIW
                     QKTDSQTSKYKNSRSTAIFNKSYELYHTDRAKKSSGKTSEIYLMEGFMDVIAAYRAGI
                     ENAVASMGTALSREHVEHLKRLTKKLVLVYDGDKAGQAAILKALDEIGDMPVQIVSMP
                     DNLDPDEYLQKNGPEDLAYLLTKTRISPIEFYIHQYKPENSENLQAQIEFIEKIAPLI
                     VQEKSIAAQNSYIHILADSLASFDYTQIEQIVNESRQVQRQNRMERISRPTPITMPVT
                     KQLSAIMRAEAHLLYRMMESPLVLNDYRLREDFAFATPEFQVLYDLLGQYGNLPPEVL
                     AEQTEEVERAWYQVLAQDLPAEISPQELSEVEMTRNKALLNQDNMRIKKKVQEASHVG
                     DTDTALEELERLISQKRRME"
     gene            10533..11642
                     /gene="rpoD"
                     /locus_tag="VYO11_001613"
     CDS             10533..11642
                     /gene="rpoD"
                     /locus_tag="VYO11_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HEV1596150.1"
                     /translation="MATKQKEVTTFDVQVAEFIRNHKQKGTATDDEINASLVIPFTLD
                     ADGIEDLLQRIQDAGISITDNEGNPSARVLSNEEEPELSDEDLIGSTSAKVNDPVRMY
                     LKEIGVVPLLTNEEEKELALAVEAGDIEAKQRLAEANLRLVVSIAKRYVGRGMQFLDL
                     IQEGNMGLMKAVDKFDYSKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETINK
                     LVREQRNLLQELGQDPTPEQIAERMDMTPDKVREILKIAQEPVSLETPIGEEDDSHLG
                     DFIEDEVIENPVDYTTRIVLREQLDEILDTLTDREENVLRLRFGLDDGKMRTLEDVGK
                     VFNVTRERIRQIEAKALRKLRQPSRSKPLRDFIED"
     gene            11656..11985
                     /locus_tag="VYO11_001614"
     CDS             11656..11985
                     /locus_tag="VYO11_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HEV1596151.1"
                     /translation="MAYTEEQIENIKTRILTALEEVIDPELGIDIVNLGLIYEIRFDG
                     DTGQTEIDMTLTTMGCPLADLLTDQIYDAMIEVPEVTDTEVKLVWYPAWTVEKMSRYA
                     RIALGIK"
     gene            12100..13143
                     /gene="cpoA"
                     /locus_tag="VYO11_001615"
     CDS             12100..13143
                     /gene="cpoA"
                     /locus_tag="VYO11_001615"
                     /EC_number="2.4.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosylglucosyldiacylglycerol synthase"
                     /protein_id="HEV1596152.1"
                     /translation="MEKKKLRINMLSSSEKVAGQGVSGAYRELVRLLHRAAKDQLIVT
                     ENLPIEADVTHFHTIDFPYYLSTFQKKRSGRKIGYVHFLPATLEGSLKIPFFLKGIVK
                     RYVFSFYNRMEHLVVVNPMFIEDLVAAGIPREKVTYIPNFVNKEKWHPLPQEEVVRLR
                     TDLGLSDNQFIVVGAGQVQKRKGIDDFIRLAEELPQITFIWAGGFSFGGMTDGYEHYK
                     KIMENPPKNLIFPGIVSPERMRELYALADLFLLPSYNELFPMTILEAASCEAPIMLRD
                     LDLYKVILEGNYRATAGREEMKEAILEYQANPAVLKDLKEKAKNISREYSEEHLLQIW
                     LDFYEKQAALGRK"
     gene            13159..14484
                     /locus_tag="VYO11_001616"
     CDS             13159..14484
                     /locus_tag="VYO11_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HEV1596153.1"
                     /translation="MRIGLFTDTYFPQVSGVATSIRTLKTELEKQGHAVFIFTTTDKD
                     VNRYEDWQIIRIPSVPFFAFKDRRFAYRGFSKALEIAKQYQLDIIHTQTEFSLGLLGI
                     WIARELKIPVIHTYHTQYEDYVHYIAKGMLIRPSMVKYLVRGFLHDVDGVICPSEIVR
                     DLLSDYKVKVEKRVIPTGIELAKFERPEIKQENLKELRSKLGIQDGEKTLLSLSRISY
                     EKNIQAVLAAFADVLKEEDKVKLVVAGDGPYLNDLKEQAQNLEIQDSVIFTGMIAPSE
                     TALYYKAADFFISASTSETQGLTYLESLASGTPVIAHGNPYLNNLISDKMFGTLYYGE
                     HDLAGAILEALIATPDMNEHTLSEKLYEISAENFGKRVHEFYLDAIISNNFQKDLAKD
                     DTVSQRIFKTVLYLQQQVVAVPVKGSRRMLKASKTQLISMRDYWKDHEE"
     gene            14515..14691
                     /locus_tag="VYO11_001617"
     CDS             14515..14691
                     /locus_tag="VYO11_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HEV1596154.1"
                     /translation="MRSGRDKKIAGVCAGVAHYLDMDPTIVQVIWGVLTCCYGAGIVA
                     YIILWIIAPVATDY"
     gene            14750..14884
                     /locus_tag="VYO11_001618"
     CDS             14750..14884
                     /locus_tag="VYO11_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HEV1596155.1"
                     /translation="MAFGDNGNRKKTMFEKITLFIVIIMLVASLLGIFATAIGALSNL
                     "
     gene            14948..16258
                     /gene="obgE"
                     /locus_tag="VYO11_001619"
     CDS             14948..16258
                     /gene="obgE"
                     /locus_tag="VYO11_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HEV1596156.1"
                     /translation="MSMFLDTAKIKVKAGNGGDGMVAFRREKYVPNGGPWGGDGGRGG
                     NVVFVVDEGLRTLMDFRYNRHFKADSGEKGMTKGMHGRGAEDLRVRVPQGTTVRDAET
                     GKVLTDLIEHGQEFIVAHGGRGGRGNIRFATPKNPAPEISENGEPGQERELQLELKIL
                     ADVGLVGFPSVGKSTLLSVITSAKPKIGAYHFTTIVPNLGMVRTQSGESFAVADLPGL
                     IEGASQGVGLGTQFLRHIERTRVILHIIDMSASEGRDPYEDYLAINKELESYNLRLME
                     RPQIIVANKMDMPESQENLEDFKKKLAENYDEFEELPAIFPISGLTKQGLATLLDATA
                     ELLDKTPEFLLYDESDMEEEAYYGFDEEEKAFEISRDDDATWVLSGEKLMKLFNMTNF
                     DRDESVMKFARQLRGMGVDEALRARGAKDGDLVRIGKFEFEFVD"
     gene            16268..16426
                     /locus_tag="VYO11_001620"
     CDS             16268..16426
                     /locus_tag="VYO11_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1596157.1"
                     /translation="MGDKPISFRDADGNFVSAADVWNEKKLEELFNRLNPNRALRLAR
                     TKKENPSQ"
     gene            complement(16477..17162)
                     /locus_tag="VYO11_001621"
                     /pseudo
     CDS             complement(16477..17162)
                     /locus_tag="VYO11_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558202.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         5301 a         2941 c         3835 g         5085 t
ORIGIN      
        1 tatcaaccaa gattaaaaga attatcattt ttacagtttt tcgagaaaat tgggaaccgt
       61 acatgaaaaa gtacacggaa gtttttcaaa gtcaatttcc taatctaaac attgattact
      121 tgctcctgga cactgagcag attgatcttg atagctatct agatgctgac ataattatca
      181 tcggtggtgg aaatacggaa aaatatattg ctaacttatg ttaatcagga gttcaaaagt
      241 tatatcgatc atatgcttaa taaagaggca aaaattatag gattttctgc aggagcccta
      301 ctattaggag aaaaagtcta tgtctcacct aatgataatt cagatcatca gataaagata
      361 aaaaatggat taggactctt tagtcagttt ttaattagtg tccattatga ttcctggaat
      421 gataaagcaa ataaggatag agctgaagaa ctcgttaatg ttcccataat tccactaaat
      481 gatcattctt gtcttgtatt ggataaactt ggaaacatca tagagaaaat tgactaactt
      541 tcataatgta aaaatggatc taggaaataa aagtgtagac gaactggata ggttactagt
      601 gaaaactgca aaaagtgttg taaagtgaat cggagtgtgc ttgatggatt ttagtagtaa
      661 gatagccata aataagggct ggtcagatga taaaaaatat tgtgtgacag atcaaaatca
      721 gtaaaaatat ttcttgcgtg tttctgataa gtcgaagtta gattataaaa aaatttgaat
      781 ttgatatgat ggagaaagta gcttctcttg gagttccgat gtgtaaacca attagcattg
      841 aactctgcga tgacgaagta cattctttac acgaatggat agacggaaga gatgcaatag
      901 atagcatttt agcttattca gaaaaccaac aatacacata tggtgtagaa gcaggaaaga
      961 tacttagaaa gattcataca attcctgcta cagaagtttg tgaagattgg gaaatttttt
     1021 taatctaaaa attgatgata aaatctccaa cgaaatgata tggtaagtcc gaaacgctca
     1081 gtgtgtaagc ttgttgctaa aagcgtaaaa accttggaac gaaaggaata atagacttcc
     1141 tgcgaaacaa aaatacaata caataaaact atggatgatg aagcaagtaa acaattaagc
     1201 gatagccgtt tcaagatcct tgtaggtgtt cagcgcacga cttttgaaga gatgttagct
     1261 gtgttaaaaa cagcttatca acgtaaacgc gcaaaaggtg gacgaaaaag caaattaagc
     1321 ctagacgatc tccttatggt aactattcaa tacatgcgag aatagagcac ttatgaacaa
     1381 attgcggctg attttggcat tcacgaaagc aacttaatcc gtcggagtca atgggttgaa
     1441 gcaactctta ttcaaaatgg ttttacgatt tcaaattctg ccttaattct gtaaaaacag
     1501 taaaattcga aggattgtaa ggtaagagtt tttttctttc tgaaaaaatg gtataatagc
     1561 aatcaaaact agaaaataaa acggaatttg gaacagattt gtctgtatcc tagtagagtg
     1621 gtgatactat gaagattagt aagaggcact tattaaatta ttccatcttg attccctact
     1681 tgcttttatc tattttgggc ttgattgtgg tctattcgac caccagtgct attttaattg
     1741 aagaaggcaa gagcgccttg cagttggttc gaaaccaagg aatcttttgg attgttagtt
     1801 tgatactgat tgccttaatt tataaattga gactagattt tttgagaaat gagcgactaa
     1861 tcattttagt tatattaata gaaatgcttt tattgttctt ggctcgtttt attggtattt
     1921 cagtaaacgg ggcatacggt tggatttcgg ttgcaggagt aactattcag ccagctgagt
     1981 acttaaaaat cattattatt tggtatttag ctcaccgatt ctccaaacag caagaagaaa
     2041 tagctactta tgattttcaa gttttgactc aaaatcaatg gcttccccgt gcttttaatg
     2101 attggcgatt cgttctccta gttctgattg gaagtttggg aattttccct gatttaggaa
     2161 atgcgactat tttagtcttg gtttccttga ttatgtatac agttagtgga atcgcttatc
     2221 gctggttttc aaccattctg gcgctcgtat ctgccacttc tgtctttgtc ttgaccacta
     2281 tcagcctaat cggtgttgag accttttcaa aaattccagt atttggctat gtagccaagc
     2341 gctttagtgc cttttttaat ccttttgccg atcgtgctga tgcgggtcat cagttagcta
     2401 attcttattt tgccatggtc aatggcggtt ggtttggtct aggtcttgga aactcgattg
     2461 aaaaacgagg ttatttgcca gaagctcata cagactttgt cttttctatc gtgattgaag
     2521 aatttggctt tgttggtgcc agtcttattt tagctctctt gtttttcatg attttgcgga
     2581 ttatcttggt cggtattcga gcggagaatc ctttcaatgc catggttgca ctcggtgtcg
     2641 gagggatgat gttggttcag gtatttgtca atatcggagg gatttcgggc ttgattccat
     2701 ctacaggagt aaccttcccc ttcttatccc agggtggaaa tagtcttcta gtcttatcag
     2761 tggcagtagc ctttgtctta aatattgatg ccagtgaaaa acgcgctaag ttgtaccgag
     2821 aattggaaaa tcaaccaatg aaccttctgt tgaagtagga taaagaaagg atagtttatg
     2881 tctcttcaaa aattagaaaa ttctagtaat aaaagtgttg tgcaagaaga agtcttgatt
     2941 ctaacagaat tactggaaga tattactaaa aatatgcttg ccccagagac ctttgaaaaa
     3001 ataatacagt tgaaagaatt atcaacgcag gaagattatc aaggtctaaa ccgtctagtg
     3061 actagcttat caaatgatga aatggtctat atttcacgct atttctctat cttgcctctt
     3121 ttgattaata tttcagagga tgtggattta gcttatgaaa tcaatcatca aaataatatt
     3181 gatcaggact atttaggtaa attatctaca acgattaaat tggtagcaga aaaggaaaat
     3241 gccgttgata tcctagaaca cttgaatgtt gttccggttt tgacagccca tccaacacaa
     3301 gtgcaacgca aaagtatgtt ggatttaaca aatcatattc atagtctttt gcgtaaatac
     3361 cgtgatgtta agttggggtt gatcaataaa gataaatggt acaatgattt gcgtcgttac
     3421 atcgaaatta tcatgcagac agacatgatt cgtgagaaaa aattaaaagt gactaacgaa
     3481 atcacgaatg ctatggaata ttataacagc tcctttttga aagctgtacc tcatttgacg
     3541 acggagtata agcgcttagc gcaagcgcat ggtctgaatt taaaacaggc taaaccaatc
     3601 accatgggta tgtggatagg tggtgaccgt gatggaaatc catttgttac agcaaagacc
     3661 ttgaagcagt ctgcactcac tcagtgtgaa gtcatcatga actactatga taaaaagatt
     3721 taccaacttt atcgtgaatt ttctctttca actagcattg tcaacgtcag caagcaagtc
     3781 agagaaatgg ctcgtcaatc caaggataac tcgatttacc gcgaaaaaga gctttaccgt
     3841 cgtgccttgt ttgatattca atcaaaaatt caggcaacta aaacctatct gattgaggat
     3901 gaagaagttg ggactcgtta tgaaaccgcc aatgatttct acaaggattt gattgccatt
     3961 cgagattctc tactagaaaa taagggcgag tccttgattt caggtgattt tgtggaatta
     4021 ttgcaggcag tagagatatt tggtttttac ttagcatcaa ttgatatgcg acaagactct
     4081 agcgtctatg aagcctgtgt ggcagaactc ttgaaatcag caggaattca ttctcgttat
     4141 agcgagttga gcgaagaaga aaagtgtgac cttctcttga aagaattaga agaagatccc
     4201 cgaattcttt ctgcgactca cgcagaaaaa tcagaattat tagcaaaaga actagctatt
     4261 tttaagacgg ctcgtgtttt gaaagataag ttgggagatg atgtcatccg tcagaccatc
     4321 atttcacatg caaccagcct ttctgatatg ctagaattag ctattctgtt aaaagaagta
     4381 ggactggtgg atacggaaag ggcgcgtgtt cagattgttc ccctttttga aacaattgaa
     4441 gacttggatc attcagagga aacaatgaga aaatatcttt ctcttagcct tgccaaaaaa
     4501 tggattgact cacgaaataa ctaccaagaa atcatgcttg gctactctga cagtaataaa
     4561 gatggcggtt acttgtcatc atgttggacc ctctacaagg ctcaacaaca attgactgct
     4621 attggagatg aatttggcgt taaggttacc ttcttccatg gtcgtggtgg tactgtcggt
     4681 cgtggtggtg ggccaaccta tgaagccatt acatctcaac cgctcaagtc tatcaaggat
     4741 cgtatccgct tgacggagca gggtgaagta attgggaata aatacggtaa caaagacgcc
     4801 gcttactata accttgaaat gctagtatcg gcagctatta accgtatgat tactcagaag
     4861 aagagtgata ccaatacccc aaatcgttat gaagccatta tggatcaagt agtggaccgt
     4921 agttacgatg tctaccgtga tttggtcttt ggtaatgagc atttctatga ttatttcttc
     4981 gagtcaagtc caatcaaggc tatttcaagt tttaatattg gttctcgtcc agccgctcgt
     5041 aagactatta ctgaaatcgg tggtttgcgt gccatccctt gggtattctc atggtcacag
     5101 agtcgtgtta tgttccctgg atggtacggg gttggttcaa gcttcaagga atttatcaat
     5161 aaaaatccag agaatattgc tatcttacga gatatgtacc aaaattggcc tttcttccaa
     5221 tcgcttcttt caaatgttga tatggttttg tcaaaatcaa atatgaatat tgcttttgaa
     5281 tatgctaaac tttgtgaaga cgagcaagtt aaggccatct atgagattat tttaaatgaa
     5341 tggcaagtta ctaagaacgt tatcttggct attgaaggac atgacgaact cttagctgac
     5401 aatccatatc taaaagctag tctggattac cgtatgcctt actttaatat tctcaactat
     5461 attcagttag agttgattaa acgccaacgt cgtggagaat tgtccagtga tcaagaacga
     5521 ttgattcata tcaccatcaa cggaattgcg acaggattgc gtaattcagg ttgataattt
     5581 tcaagagtga atgctaaaag tgaatatcaa aaaaattcta atagactatt gacaagtagt
     5641 ttaaaaatga tataatttaa ccattcagaa agtaatcata caaacttttt agagagtctg
     5701 tggtagctga aaacagataa gtggcaatga tgaaaattgg gctgaatgct atttagaatt
     5761 tgaaattata aaaattcggt aagcacacct tacagtgcat ctcgttattg cgagactgag
     5821 cgatagggaa attccctata attgaggtgg taccgcgcat cgacgtcctc acacaagttt
     5881 tttgtgtgag gatttttttg atggaggtta gtatggaaag aaaacgatgg cgtcgcttgt
     5941 ttagataagt gaaatatgtt aaaggaaata aaaaggagaa acagaatgaa aaataaacgt
     6001 ttaattggaa ttattgctgc attagcagtc ttagtagcag gaagcttgat ttattcttca
     6061 atgaataaat cagaagctca gaataataag gatgagaaga aaataaccaa gattggtgtg
     6121 cttcaatttg tgagccatcc atcccttgat ttgatttata aagggatcca agatggactt
     6181 gcagaagaag gatataaaga tgatcaagtt aaaattgatt ttatgaactc agaaggtgac
     6241 caaagtaagg ttgcgacaat gagtaaacaa ttggttgcaa atgggaatga ccttgtggtt
     6301 ggtatcgcaa caccagcagc ccaagggttg gctagtgcaa caaaagacct accggttatc
     6361 atggccgcta ttacagaccc aattggtgct aacttggtta aagatttgaa aaaaccaggt
     6421 ggcaacgtta caggggtatc tgaccacaat ccagctcaac aacaagttga actcatcaag
     6481 gctctgacac cgaatgtgaa aacaatcgga gctctttact caagtagcga agacaattca
     6541 aaaacacagg tcgaagaatt taaggcttat gctgaaaaag caggtctgac agtggaaaca
     6601 tttgcagttc cttcaacaaa tgaaattgcc tcaactgtca ctgttatgac tagcaaggta
     6661 gatgctattt gggttccaat tgataacacc attgcatcag gatttccaac ggttgtctct
     6721 agcaatcaaa gttctaagaa accaatttat cccagtgcga cagctatggt agaagtaggt
     6781 ggtttggcat cagttgtaat tgaccaacat gaccttggtg tggcaacagg taaaatgatt
     6841 gtgcaagtct tgaaaggtgc aaaaccagcc gataccccag tcaatgtctt ttcaactggt
     6901 aagtcagtca tcaataaaaa aatagcacaa gaactaggta ttactattcc tgagtctgtt
     6961 ctcaaagaag caggacaagt catcgaataa ataaggtagg gaggaggaga ctcttcccat
     7021 tttttaaaaa gatgaatata gaaaggatta aataaaatat gattgtttcc attatttctc
     7081 aaggatttgt ctgggctatt ctaggtctgg gaatctttat gacatttagg attttaaact
     7141 ttccagatat gacgacagaa ggttccttcc ctcttggggg agctgttgct gtcactttga
     7201 taaccaaagg cgtgaaccca tttttagcga cacttgttgc tgtaggagca ggttgtttgg
     7261 ctggaatggc agcaggcctt ctttatacaa aagggaagat cccaaccttg ctctcaggga
     7321 ttttggtgat gacttcttgt cactcaatca tgctcttgat tatgggacgt gcaaatttag
     7381 gcctgcttgg aaccaagcaa attcaggatg ttttgccttt tgattcggat ttgaatcaac
     7441 tcttgacagg tctcatcttt gtgagtattg ttattgctct catgctcttt ttcttggaca
     7501 ctaaactcgg acaagcctat attgctacag gggataatcc tgatatggct agaagtttcg
     7561 ggattcatac tggacgcatg gagctcatgg gcttggtctt atcaaatggt gtgattgccc
     7621 ttgcaggtgc cctcattgct cagcaagaag gctatgccga tgtatctcga gggatcgggg
     7681 ttatcgttgt ggggcttgca agtttgatta ttggagaagt tattttcaag agtttgagct
     7741 tggcagagcg tttggttact atcgttgtag gttctatcgc ttatcaattt ttagtgtggg
     7801 cagttatcgc acttggcttt aatacaagtt accttcgttt atacagtgcc ttgattttag
     7861 cagtctgcct catgattcca acatttaagc aaacaatctt gaaaggagcc aagttaagca
     7921 aatgacagca attgtagaat taaaaaatgc aaccaaaatc gttaaaaatg gctttgatga
     7981 agaaaagatt attttaaatg atgtttcctt aaaaattttt gaacgggact ttatcacgat
     8041 tttgggcgga aatggtgctg gaaaatcaac cctctttaac actatagcag ggaccttatc
     8101 actaactagt ggaactatcc gtattttagg tgaagatctc actaagtttt cacccgagaa
     8161 gcgtgccaag tacctgtctc gtgtcttcca agatccaaag atggggacag ctccccgtat
     8221 gacggtcgct gaaaatcttt taatcgccaa gtttcgtggt gaaaagcgtg gattgttacc
     8281 acgacgcttg actagctata aggatgaatt tcaggcaact attgaaaaag taggaaatgg
     8341 tcttgagaaa cacttgaata caccgattga gttcttatct ggtggacaaa gacaggcttt
     8401 gagtctcttg atggcaacct tgaagcgacc tgaattactc ttgttagacg agcatactgc
     8461 tgccctggat ccaaagacta gtgttgcttt gatggaattg acagatgaat ttgttaagaa
     8521 agatcaattg acagccctta tgattaccca tcatatggaa gatgctctca aatatggcaa
     8581 tcgcttgatt gtcatgaaag aaggacgggt tatccaagat ttgaaacaag aagaaaaagc
     8641 aaaaatgaaa atctctgatt attatcaact ctttgaataa agtagggaaa atgagtgaaa
     8701 tggtttactt tttttctgaa ataaagtata ctatataaag taaactatga taacatggag
     8761 gtattgtgta tggttgacaa acaagtcatt gaagaaatca aaaacaatgc caacattgtg
     8821 gaagtcatag gagatgtgat ttctttacaa aaggcaggac ggaactatct agggctctgt
     8881 ccttttcatg gtgaaaaaac accttctttc aacgttgtag aggacaagca gttttaccac
     8941 tgttttggtt gtggtcgctc aggtgatgtc tttaaattca tcgaggagta ccaaggggtt
     9001 acctttatgg aggctgtcca aatcttaggt cagcgtgtcg ggattgaggt tgaaaaaccg
     9061 ctttatagtg aacagaagcc agcctcgcct taccaagctc tttatgatat gcacgaagat
     9121 gcggctaaat tttaccatgc tattctcatg acaacgacta tgggcgaaga ggccagaaat
     9181 tacctttatc agcggggttt gacagatgaa gtgcttaaac atttttggat tggtttagca
     9241 cctccagaac gaaactatct ctatcaacgt ttgtctgatc agtatcgtga agaggattta
     9301 ctggattcag gtctgtttta tctctcggat gccaatcaat ttgtagacac ctttcacaat
     9361 cgcattatgt ttcccctgac aaatgaccaa ggaaaggtca ttgccttctc aggtcgtatc
     9421 tggcaaaaaa cggattcaca aacttctaag tataaaaaca gccgatcgac tgcaattttt
     9481 aacaaaagtt acgaattata tcatacggat agggcaaaaa aatcttctgg aaaaactagt
     9541 gagatttacc tgatggaagg attcatggat gttattgcag cctatcgggc tggaatcgaa
     9601 aatgctgtgg cgtcgatggg aacggccttg agtcgagagc atgttgagca tctgaaaagg
     9661 ttaaccaaga aattggttct tgtttacgat ggagataagg ctgggcaagc cgcgatattg
     9721 aaagcattgg atgaaattgg tgatatgcct gtgcaaatcg ttagcatgcc tgataacttg
     9781 gatcctgatg agtatctaca aaaaaatggt ccagaagact tggcctatct attaacaaaa
     9841 actcgtatta gtccgattga gttctacatt catcagtaca aacctgaaaa cagtgaaaat
     9901 ctgcaggctc agattgagtt tattgaaaaa atagctccct tgattgttca agaaaagtcc
     9961 atcgctgctc aaaacagcta tattcatatt ttagctgaca gtctggcgtc ctttgattat
    10021 acccagattg agcagattgt taatgagagt cgtcaggtgc aaaggcagaa tcgcatggaa
    10081 agaatttcca gaccgacgcc aatcaccatg cctgtcacca agcagttatc ggctattatg
    10141 agggcagaag cccatctact ctatcggatg atggaatccc ctcttgtttt gaacgattac
    10201 cgtttgcgag aagactttgc atttgctaca cctgaatttc aggtcttata tgacttgctt
    10261 ggccagtatg gaaatcttcc tccagaagtt ttagcagagc agacagagga agttgaaaga
    10321 gcttggtacc aagttttagc tcaggatttg cctgctgaga tatcgccgca ggaacttagt
    10381 gaagtagaga tgactcgaaa caaggctctc ttgaatcagg acaatatgag aatcaaaaag
    10441 aaggtgcagg aagctagcca tgtaggagat acagatacag ccctagaaga attggaacgt
    10501 ttaatttccc aaaagagaag aatggagtaa taatggcaac aaaacaaaaa gaagtaacaa
    10561 catttgacgt acaggtagca gaatttatcc gtaatcataa gcaaaaaggg acagcaacag
    10621 atgatgaaat caatgcaagt ctggttattc cttttacctt ggacgctgat gggattgaag
    10681 atctcttgca acggattcag gatgcaggca tttctatcac agataacgaa ggaaatccaa
    10741 gtgcgcgtgt tcttagcaat gaagaagaac cagaactcag cgatgaggac ttgattgggt
    10801 caacttctgc taaggtcaat gaccctgtcc gtatgtactt gaaagaaata ggggtcgttc
    10861 ctctcttgac caatgaagag gagaaagagt tggcactggc tgttgaagct ggcgatatcg
    10921 aagccaaaca acgtcttgcg gaagccaatc ttcgtttggt tgtttctatt gccaaacgct
    10981 atgtcggtcg tggcatgcag ttccttgact tgattcaaga aggaaatatg ggcttgatga
    11041 aggcggttga caagtttgac tattctaaag ggttcaagtt ttcaacttat gcaacttggt
    11101 ggattcgtca ggctatcact cgtgctattg cggatcaagc tcgtaccatc cgtatcccag
    11161 ttcacatggt tgaaactatc aataaattgg ttcgtgaaca gcggaatctc cttcaagaat
    11221 tggggcaaga tccgacacca gaacagattg ctgaacgaat ggatatgaca cctgataagg
    11281 ttcgtgaaat cttgaagatt gcccaagaac cagtatctct tgaaactcct atcggtgaag
    11341 aagacgatag ccaccttgga gactttatcg aagatgaagt gattgaaaat ccagtggatt
    11401 atacgactcg tatcgtcttg cgtgagcaat tggatgaaat cttagatact cttacagacc
    11461 gtgaagaaaa tgttctgcgt ctacgttttg gactagatga tggaaaaatg cgcacacttg
    11521 aagatgtggg gaaagtcttt aacgtaactc gtgagcgtat ccgtcagatt gaagcaaagg
    11581 ctttgagaaa actacgccaa ccaagccgca gcaaaccgct tcgtgatttt attgaagact
    11641 aagagtgagg aaaatatggc ttatacagaa gagcaaattg aaaacatcaa aacacggatt
    11701 ttaacagcct tggaagaagt catcgaccct gagttgggaa tcgatattgt caatcttggt
    11761 ttgatctatg agattcgttt tgacggtgac acagggcaaa cagagattga catgactttg
    11821 acaactatgg gttgtccctt agcagacctt ttgacagacc agatttatga tgctatgata
    11881 gaggttccag aagtaacgga tactgaggtt aaattagtct ggtatccagc ctggacagtt
    11941 gaaaaaatga gtcgctatgc ccgcattgcc ctaggcatta agtaaacata taaaagcatg
    12001 tgagagactg ttggaaaagc gaggaaattt cccctctttt cctctagtct ctcctttctt
    12061 ttgctgattt tattcaaaga aaatgatata atagtagtta tggagaaaaa gaaattacgc
    12121 atcaatatgt tgagttcaag tgagaaagta gcaggacagg gagtttcagg tgcttaccgt
    12181 gaattagttc gtcttcttca ccgtgctgcc aaggaccaat tgattgttac agaaaatctt
    12241 ccaatcgagg cagatgtgac tcactttcat acgattgatt ttccctatta tttatcaacc
    12301 ttccaaaaga aacgctcagg gagaaagatt ggctatgtgc atttcttgcc agctacactt
    12361 gagggaagtt tgaaaattcc atttttctta aagggaattg tgaaacgcta tgtattttct
    12421 ttttacaacc ggatggagca cttggttgtg gtcaatccta tgtttattga ggatttggta
    12481 gcagctggta ttccacgtga aaaagtgacc tatattccta actttgtcaa caaggaaaaa
    12541 tggcatcctc taccacaaga agaggtagtc agactgcgca cagatcttgg tcttagtgac
    12601 aatcagttta tcgtagtagg tgctgggcaa gttcagaaac gtaaagggat tgatgacttt
    12661 atccgtctgg ctgaggaatt gcctcagatt acctttatct gggctggtgg cttctctttt
    12721 ggtggtatga cagatggtta tgaacactat aagaaaatta tggaaaatcc ccctaaaaat
    12781 ttgatttttc caggcattgt atcgccagag cggatgcgcg aattgtatgc tctagcggat
    12841 cttttcttgt tgcctagtta caatgagctc tttcctatga ctattttaga agctgcgagt
    12901 tgtgaggctc ctattatgtt gcgtgattta gatctctata aggtgatttt ggagggaaat
    12961 tatcgggcga cagcgggtag agaagagatg aaagaggcta ttttggaata tcaagcaaat
    13021 cctgctgtct taaaagatct caaagaaaag gctaagaata tttccagaga gtattctgaa
    13081 gagcatctgt tacaaatctg gttggacttt tatgagaaac aagccgcttt agggagaaag
    13141 taaaaagtga ggtaatctat gcgaattggt ttatttacag atacctattt tcctcaggtt
    13201 tctggtgttg cgaccagtat tcgaaccttg aaaacagaac ttgaaaagca gggacatgct
    13261 gtttttatct ttacgacgac agataaggat gtcaatcgct acgaagattg gcaaattatc
    13321 cgcattccaa gtgttccttt ctttgctttt aaggatcgtc gctttgccta ccgaggtttt
    13381 agcaaggcac ttgaaattgc taaacagtat cagctagata ttatccatac tcagacagaa
    13441 ttttctcttg gcctgttggg gatttggatt gcgcgtgaat tgaaaattcc agtcatccat
    13501 acctatcaca cccagtatga agactatgtc cattatattg ctaaggggat gttgatccgg
    13561 ccgagtatgg tcaagtatct ggttagaggt ttcctgcatg atgtggatgg ggttatttgc
    13621 cctagtgaga ttgtccgtga cttgctatct gattataagg tcaaggttga aaaacgggtc
    13681 attcctactg ggattgaatt agccaagttt gagcgtccgg aaatcaagca ggaaaatttg
    13741 aaagaactgc gtagtaaact agggattcaa gatggtgaaa agacgttgct tagtctttcg
    13801 agaatctcct atgaaaaaaa tattcaagca gttttagcag cctttgctga tgttctgaaa
    13861 gaggaagaca aggttaaact ggtagtagct ggggatggcc cttatctgaa tgacctcaaa
    13921 gagcaagccc agaacctaga gattcaagac tcagtcatct ttacagggat gattgctcct
    13981 agtgagacgg ctctttacta taaagcggcg gatttcttca tttcggcatc gacaagcgaa
    14041 acgcaaggtt tgacctactt ggaaagctta gccagtggaa cacctgtcat tgctcacgga
    14101 aatccttatt tgaacaacct catcagtgat aaaatgtttg gaaccttgta ctatggagaa
    14161 catgatttgg ctggtgctat tttggaagcc ctgattgcaa caccagacat gaacgagcat
    14221 accttatcag agaaattgta tgagatttca gctgagaact ttgggaaacg agtgcatgag
    14281 ttttatctgg atgccattat ttcaaataac ttccagaaag atttggctaa agatgatacg
    14341 gtcagtcagc gtatctttaa gacagttttg tatcttcagc aacaggtggt tgctgtacct
    14401 gtaaaaggat ctagacgcat gttgaaggct tcaaaaacac agttgatcag tatgagagac
    14461 tattggaaag accatgaaga atagaaagag gaacagctat gaaaaaaaca attaatgaga
    14521 agcggtcgtg ataaaaagat tgcgggtgtt tgtgctgggg tggcccatta tctggatatg
    14581 gatccgacta tcgttcaagt catttggggt gttcttactt gctgttacgg agctggaatt
    14641 gtagcttaca ttattttatg gattatcgca ccagtagcaa ctgactattg aaaactagct
    14701 caattcatgc taagataata gaaaatagaa tgtaacgaag gagagaaaaa tggcatttgg
    14761 agataatgga aatcgtaaaa aaactatgtt tgagaaaata accttgttta tcgtgattat
    14821 catgctagta gcaagtttat tgggaatttt tgcaactgca attggtgccc tcagtaatct
    14881 ataaaataga ttcaagaaaa tttagtgact gggatttccc agcccttttt taaagtgaga
    14941 agaaataatg agtatgtttt tagatacagc taagattaag gtcaaggctg gtaatggtgg
    15001 cgatggtatg gttgcctttc gtcgtgaaaa atatgtccct aatggaggcc cttggggtgg
    15061 tgatggtggt cgtggaggca atgtggtctt cgttgtagac gaaggactac gtaccttgat
    15121 ggatttccgc tacaatcgtc atttcaaggc tgattctggt gaaaaaggga tgaccaaagg
    15181 gatgcatggt cgtggtgctg aggaccttag agttcgagta ccacaaggta cgactgttcg
    15241 tgatgcggag actggcaagg ttttaacaga tttgattgaa catgggcaag aatttatcgt
    15301 tgcccacggt ggtcgtggtg gacgtggaaa tattcgtttc gcgacaccaa aaaatcctgc
    15361 accggaaatc tctgaaaatg gagaaccagg tcaggaacgt gagttacaat tggaactaaa
    15421 aatcttggca gatgtcggtt tagtaggatt cccatctgta gggaagtcaa cacttttaag
    15481 tgttattacc tcagctaagc ctaaaattgg tgcctaccac tttaccacta ttgtaccaaa
    15541 tttaggtatg gttcgcaccc aatcaggtga atcctttgca gtagccgact tgccaggttt
    15601 gattgaaggg gctagtcaag gtgttggttt gggaactcag ttcctccgtc acatcgagcg
    15661 tacacgtgtt atccttcaca tcattgatat gtcagctagc gaaggccgtg atccatatga
    15721 ggactaccta gctatcaata aagagctgga gtcttacaat cttcgcctca tggagcgtcc
    15781 acagattatt gtagctaata agatggacat gcctgagagt caggaaaatc ttgaagactt
    15841 taagaaaaaa ttggctgaaa attatgatga atttgaagag ttaccagcta tcttcccaat
    15901 ttctggattg accaagcaag gtctggcaac acttttagat gctacagctg aattgttaga
    15961 caagacacca gaatttttgc tctacgacga gtccgatatg gaagaagaag cttactatgg
    16021 atttgacgaa gaagaaaaag cctttgaaat tagtcgtgat gacgatgcga catgggtact
    16081 ttctggtgaa aaactcatga aactctttaa tatgaccaac tttgatcgtg atgaatctgt
    16141 catgaaattt gcccgtcagc ttcgtggtat gggggttgat gaagcccttc gtgcgcgtgg
    16201 agctaaagat ggggatttgg tccgcattgg taaatttgag tttgaatttg tagactagga
    16261 gactggtatg ggagataaac cgatatcttt ccgagatgcg gatggtaatt ttgtttccgc
    16321 cgcagacgtt tggaatgaaa agaaattgga agaactattt aatcgtctca atccaaatcg
    16381 tgccttgaga ttggcacgaa ctaaaaagga aaatccatct cagtaaagaa gctaaaaaat
    16441 cccggctctt tgtcaactgt agtgggttga agtcagctaa gctcgagaaa ggacaaattt
    16501 cgtcctttct tttttgatgt taagagcgat aaaaatccgt tttttgaagt tttcaaagtt
    16561 tcgaaaacca aaggcattgc gtttgatgag attattggtc gcttccaatt tggcgtttga
    16621 atagggtagt tgaagggcgt tgacgatttt ctctttgtcc tttagaaagg ttttaaagac
    16681 agtctgaaaa agaggatgaa cctgcttaag attgtcctca ataagtccga aaaatttctc
    16741 agggtctttg ttctgaaagt gaaacagcaa gagttgatag atctgataga tctgatagtg
    16801 gtgtttcaag tcttgtgaat agcttaaaat cttgtcaaga atttctttat ttgttaagtg
    16861 catgcgaaaa gtagggcgat aaaaatgttt atcgctgagt ttacggctat cctgttgaat
    16921 gagtttccag tagcgcttga tagccttgta tttatgggat tttcgatgaa actgattcat
    16981 gatttgaaca cgcacacgac tcatagcacg actaagatgt tgtacaatgt gaaagcgatc
    17041 aagaacgatt ttagcattcg ggagtgaaac agtctgggag actgtttcag cctgagccta
    17101 gaaatttgaa agcgaggctg tttagctaag tcatagtaag ggctaaacat atccatagta
    17161 at
//
LOCUS       DAVLXH010000046        16572 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00028199
            SAMN33607166-rid17955573.denovo.046, whole genome shotgun sequence.
ACCESSION   DAVLXH010000046 DAVLXH010000000
VERSION     DAVLXH010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607166
            Sequence Read Archive: SRR23725544
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16572)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16572)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721421.1
            Genome Coverage       :: 115x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:42:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,210
            CDSs (total)                      :: 2,161
            Genes (coding)                    :: 2,023
            CDSs (with protein)               :: 2,023
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 73 of 138
            Pseudo Genes (incomplete)         :: 60 of 138
            Pseudo Genes (internal stop)      :: 40 of 138
            Pseudo Genes (multiple problems)  :: 31 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16572
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607166-rid17955573.denovo.046"
                     /strain="AUSMDU00028199"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1349"
     gene            complement(107..823)
                     /locus_tag="VYO11_001622"
     CDS             complement(107..823)
                     /locus_tag="VYO11_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001007200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEV1596158.1"
                     /translation="MAIPKYQYIKDELKNKIISGQFSSGDKFYTEAELISMYDVSSIT
                     VVRALNDLAKDGYIVRQQGKGTFVSRARKHKLVEFSDIELFNAKDDKVTVLSIERGNK
                     LVYLEKLGLRGDQFYYKIERIRESNGVVYIYHTSYIPEQYINANYPNLEYYSSIYNRF
                     KLDYHIHMNDEHFEEINEIVFPTPEHAASVLGVDEHFPTVLQTKITKLESTGQVLEYS
                     ETYKRSDYYKIKFISCDRDH"
     gene            1171..2958
                     /locus_tag="VYO11_001623"
     CDS             1171..2958
                     /locus_tag="VYO11_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase"
                     /protein_id="HEV1596159.1"
                     /translation="MTRFEIRDDFYLDGKSFKILSGAIHYFRVPPEDWYHSLYNLKAL
                     GFNTVETYVAWNLHEPREGEFHFEGDLDLEKFLQIAQDLGLYAIVRPSPFICAEWEFG
                     GLPAWLLTKNMRIRSSDPAYIEAVGRYYDQLLPRLVPRLLDNGGNILMMQVENEYGSY
                     GEDKAYLRAIRQLMEECGVTCPLFTSDGPWRATLKAGTLIEEDLFVTGNFGSKAPYNF
                     SQMQEFFDEHGKKWPLMCMEFWDGWFNRWKEPIITRDPKELADAVREVLEQGSINLYM
                     FHGGTNFGFMNGCSARGTLDLPQVTSYDYDALLDEEGNPTAKYLAVKKMMATHFSEYP
                     QLEPLYKESMELDAIPLVEKVSLFETLDSLSSPVESLYPQKMEELGQSYGYLLYRTET
                     NWDAEEERLRIIDGRDRAQLYVDGQWVKTQYQTEIGEDIFYQGKKNGLSRLDILIENM
                     GRVNYGHKFLADTQRKGIRTGVCKDLHFLLNWKHYPLPLDNPEKIDFSKGWTQGQPAF
                     YAYDFTVEEPKDTYLDLSEFGKGVAFVNGQNLGRFWNVGPTLSLYIPHCYLKEGANRI
                     IIFETEGQYKEEIHLTRKPTLKHIKGENL"
     gene            2955..3431
                     /locus_tag="VYO11_001624"
     CDS             2955..3431
                     /locus_tag="VYO11_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HEV1596160.1"
                     /translation="MTIVGCRIDGRLIHGQVANLWAGKLNVSRIMVVDDEVVNNDIEK
                     SGLKLATPPGVKLSILPVEKAAANILAGKYDSQRLFIVARKPDRFLGLVEAGVPLETL
                     NVGNMSQTPETRSITRSINVVDKDVEDFHKLAEKGVKLTAQMVPNDPISDFLSLLK"
     gene            3459..4364
                     /locus_tag="VYO11_001625"
     CDS             3459..4364
                     /locus_tag="VYO11_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEV1596161.1"
                     /translation="MIQWWQILLLTLYSAYQICDELTIVSSAGSPVFAGFITGLIMGD
                     VTTGLLIGGNLQLFVLGVGTFGGASRIDATSGAVLATAFSVSQGIDAPLAITTIAVPV
                     AALLTYFDVLGRMTTTFFAHRVDAAIERFDYKGIERNYLLGAIPWALSRALPVFFALA
                     FGGAFVQSVVDFVEAYKWVADGLTLAGRMLPGLGFAILLRYLPVKRNLHYLAMGFGLT
                     AMLTVLYSYVTGLGGAVAGIVGTLPAEVAEKIGFVNNFKGLSMIGISIVGIFLAVLHF
                     KNSQKVAVAAPSTPSESGEIEDDEF"
     gene            4351..5166
                     /locus_tag="VYO11_001626"
     CDS             4351..5166
                     /locus_tag="VYO11_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEV1596162.1"
                     /translation="MTNSNYKLTKEDFNQINKRSLFTFQLGWNYERMQASGYLYMILP
                     QLRKMYGDGTPELKEMMKVHTQFFNTSPFFHTIIAGFDLAMEEKDGVGSKDAVNGIKT
                     GLMGPFAPLGDTIFGSLVPAIMGSVAATMAIAGQPWGIFLWIAVAVAYDIFRWKQLEF
                     AYKEGVNLINNMQSTLTALIDAASVLGVFMMGALVATVINFEISYKLPIGEKMIDFQD
                     ILNQIFPRLLPAIFTAFIFWLLGKKGMNSTKAIGIIIVLALALSALGHFALGM"
     gene            5173..5577
                     /locus_tag="VYO11_001627"
     CDS             5173..5577
                     /locus_tag="VYO11_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007284837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV1596163.1"
                     /translation="MTKSLILVSHGRFCEELRGSTEMIMGPQDNIYTVALLPEDGPEE
                     FTAKFEAVIEGLDDFLVFADLLGGTPCNVVSRLIMEGRDIDLYAGMNLPMVIEFINAS
                     LTGADADYKSRAAESIVKVNDLLAGFDDDEDE"
     gene            5825..6991
                     /locus_tag="VYO11_001628"
     CDS             5825..6991
                     /locus_tag="VYO11_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HEV1596164.1"
                     /translation="MLHYTKEDLLELGAEITTREIYQQPDVWREAFEFYQAKREEIAA
                     FLQEIADKYDYIKVILTGAGTSAYVGDTLLPYFKEVYDERKWNFNAIATTDIVANPAT
                     YLKKDVATVLVSFARSGNSPESVATVDLAKSLVDELYQVTITCAADGKLALQAHGDDR
                     NLLLLQPAVSNDAGFAMTSSFTSMMLTALLVFDPTEFAVKSERFEVVSSLARKVLDKA
                     EDVKELVDLDFNRVIYLGAGPFFGLAHEAQLKILELTAGQVATMYESPVGFRHGPKSL
                     INDNTVVLVFGTTTDYTRKYDLDLVREVAGDQIARRVVLLSDQAFGLENVKEVALGCG
                     GVLNDIYRVFPYIVYAQLFALLTSLKVENKPDTPSPTGTVNRVVQGVIIHEYQK"
     gene            7107..8144
                     /locus_tag="VYO11_001629"
     CDS             7107..8144
                     /locus_tag="VYO11_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HEV1596165.1"
                     /translation="MKAYTERVFGNVEGEDVLAYRFETDGGYQLEVMTYGATILRYVA
                     PDKAGNFANVILGFDDFDSYVGNSPKHGASVGPVAGRIAGATFELNGKTYDLEVNNAS
                     NCNHSGSTGWDSSLFEVEEVSDHGLTLYTERTDGTGGFPGNLKIWISYHLEETGAYEI
                     SYKVTTDQDTLVNPTNHSYFNLSGDFTQTIDRHVFQLNTEGIYSIAPDGVPAKTPEAN
                     RDVVKHIYNGTLLKDIFAEEDEQIQLASGLDHPFALPVGHDNAGFLYDQNSGRFLLFK
                     TEAPCFVVYTANFVDESVIIGGQPMLQHNGIALEAQALPDAIHSDLKGQVILKAGQTF
                     TSKTRYELVVK"
     gene            8351..9205
                     /locus_tag="VYO11_001630"
     CDS             8351..9205
                     /locus_tag="VYO11_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEV1596166.1"
                     /translation="MTYEYKSHIYLAETVLNVKDLASQTAFYQQVIGLEILSQTETES
                     ILGLGEKVLVQLIQAQESGEVREHYGLYHLAILLPTRKALADVLKHLTDLQIPLVGGA
                     DHGYSEAIYLEDLEGNGIELYRDKPVSTWDIREDGRIIGVTEALAAQDIYELGERVEP
                     FILAEGTRMGHIHLSVKDSRKSSQFYQKVLGLEDKFSVPSASWIAAGDYHHHLAVNEW
                     GGKGLASRKQGLPGLAYYVIEVAHKKELLTIAQRAQEVDAPIKWMTSSKLEITDSDGI
                     VTRIRLAR"
     gene            9355..9595
                     /locus_tag="VYO11_001631"
                     /pseudo
     CDS             9355..9595
                     /locus_tag="VYO11_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845567.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensing transcriptional repressor"
     gene            complement(9926..10018)
                     /locus_tag="VYO11_001632"
                     /pseudo
     CDS             complement(9926..10018)
                     /locus_tag="VYO11_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(10054..10350)
                     /locus_tag="VYO11_001633"
     CDS             complement(10054..10350)
                     /locus_tag="VYO11_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000450185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEV1596167.1"
                     /translation="METSISMADFYGKYQNENLELIDVREAHEFQAGHAPGAKNLPLS
                     TLEQGYKELKPDHEYYVICQGGVRSASTCQFLISQGLTVTNVEGGMNAWPGQVE"
     gene            complement(10340..10501)
                     /locus_tag="VYO11_001634"
     CDS             complement(10340..10501)
                     /locus_tag="VYO11_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014932007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(FAD)-dependent dehydrogenase"
                     /protein_id="HEV1596168.1"
                     /translation="MDKKQAYIVSCHSGLRSYIAEPILKQAGFTAQNLDGAYSLYKMV
                     NPEGVEYGN"
     gene            10571..11335
                     /locus_tag="VYO11_001635"
     CDS             10571..11335
                     /locus_tag="VYO11_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside phosphorylase"
                     /protein_id="HEV1596169.1"
                     /translation="MIQKHAIPILEFDDNPQAVIMPNHEGLDLQLPKKCVYAFLGEEI
                     DRYAREVGANCVGEFVSATKTYPVYVINYKGEEVCLAQAPVGSAPAAQFMDWLVGYGV
                     EQIISTGTCGVLADIEENAFLVPVRALRDEGASYHYVAPSRYMEMQPEAIAAIEEVLE
                     DRGIPYEEVMTWTTDGFYRETAEKVAYRKEEGCAVVEMECSALAAVAQLRGVLWGELL
                     FTADSLADLDQYDSRDWGSEAFNKALELSLASVHHL"
     gene            11900..13279
                     /locus_tag="VYO11_001636"
     CDS             11900..13279
                     /locus_tag="VYO11_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000897732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HEV1596170.1"
                     /translation="MLFKLSKEKIELGLSRLSPARRIFLSFALVILLGSLLLSLPFVQ
                     VESSRATYFDHLFTAVSAVCVTGLSTLPVAHTYNIWGQIICLLLIQIGGLGLMTFIGV
                     FYIQSKQKLSLRSRATIQDSFSYGETRSLRKFVYSIFLTTFLVESLGAILLSFRLIPQ
                     LGWGRGLFSSIFLAISAFCNAGFDNLGSTSLFAFQTDLLVNLVIAGLIITGGLGFMVW
                     FDLAGHVGRKKKGRLHFHTKLVLLLTIGLLLFGTATTLFLEWNNAGTIGNLPVADKVL
                     VSFFQTVTMRTAGFSTIDYTQAHPVTLLIYILQMFLGGAPGGTAGGLKITTFFVLLVF
                     ARSELLGLPHANVARRTIAPRTVQKSFSVFIIFLMSFLIGLILLGITAKGNPPFIHLI
                     FETISALSTVGVTANLTPDLGKLALSVIMPLMFMGRIGPLTLFVSLADYHPEKKDMIH
                     YMKADISIG"
     gene            13293..13958
                     /locus_tag="VYO11_001637"
     CDS             13293..13958
                     /locus_tag="VYO11_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001283913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HEV1596171.1"
                     /translation="MSDRTIGILGLGIFGSSVLAALAKQDMNIIAIDDHAERINQFEP
                     VLARGVIGDITDEELLRSAGIDTCDTVVVATGENLESSVLAVMHCKSLGVPTVIAKVK
                     SQTAKKVLEKIGADSVISPEYEMGQSLAQTILFHNSVDVFQLDKNVSIVEMKIPQSWA
                     GQSLSKLDLRGKYNLNILGFREQENSPLDVEFGPDDLLKADTYILAVINNQYLDTLVA
                     LNS"
     gene            14088..14168
                     /locus_tag="VYO11_001638"
                     /pseudo
     CDS             14088..14168
                     /locus_tag="VYO11_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            14314..14763
                     /locus_tag="VYO11_001639"
     CDS             14314..14763
                     /locus_tag="VYO11_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV1596172.1"
                     /translation="MKLLSIAISSYNAAAYLHYCVESLVIGGEQVEILIINDGSQDQT
                     QEIAECLASKYPNIVRAIYQENKGHGGVVNCGLAEASGRYFKVVDSDDWVDPRAYLKI
                     LETLQELESKGQEVDAFVTNFVYEKEGQSRKKSMSYESVLPVRQIFD"
     gene            14920..15330
                     /locus_tag="VYO11_001640"
     CDS             14920..15330
                     /locus_tag="VYO11_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 2"
                     /protein_id="HEV1596173.1"
                     /translation="MYYLPVDFYRYLIGREDQSVNEQVMIKRIDQQLKVNRLLVDQLD
                     LSQVSHPKMREYLLNHIEITTVISSTLLNRSETAEHLAKKRQLWTYIQQKNPEVFQAI
                     RKTMLSRLTKHSVLPDRKLSNVVYQITKSVYGFN"
     gene            15446..>16572
                     /gene="pavB"
                     /locus_tag="VYO11_001641"
     CDS             15446..>16572
                     /gene="pavB"
                     /locus_tag="VYO11_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding SSURE repeat adhesin PavB"
                     /protein_id="HEV1596174.1"
                     /translation="MKFNPNQRYTRWSIRRLSVGVASVVVASGFFVLVGQPSSVRADV
                     VNPTPGQVLPEETSGTKEGDLSEKPGDTVLTQAKPEGVTGNTNSLPTPTERTEVSEET
                     NSSSLDTLFEKDEEAQKNPELTDVLKETVDTADVDGTQASPAETTPEQVKGGVKENTK
                     DSIDVPAAYLEKAEGKGPFTAGVNQVIPYELFAGDGMLTRLLLKASDNAPWSDNGTAK
                     NPALPPLEGLTKGKYFYEVDLNGNTVGKQGQALIDQLRSNGTQTYKATVKVYGNKDGK
                     ADLTNLVATKNVDININGLVAKETVEKAVKDNVKDSIDVPAAYLEQAKGEGPFTAGVN
                     HVIPYELFAGDGMLTRLLLKASDKAPWSDNGDAKNPALSPLG"
BASE COUNT         4650 a         3113 c         3759 g         5050 t
ORIGIN      
        1 atattccaca aattatagaa tcttccaaaa ataggtaagc gctacctttt tggtgtggta
       61 taataagcat agaaaaagcc cgagcgatta ggctcaggct ttcttcttag tgatcacggt
      121 cacatgagat gaatttaatc ttgtagtaat cagatcgttt gtaagtttca ctgtattcta
      181 aaacttggcc agttgattcg agtttggtga ttttagtttg taggacagta gggaaatgtt
      241 catcgactcc gaggactgaa gccgcatgtt ctggagttgg aaagactatt tcgttgattt
      301 cttcaaagtg ttcatcattc atgtgaatgt ggtagtctaa cttgaaacga ttatagatag
      361 aactatagta ttcaaggttt ggataatttg cgttgatata ttgttctggg atgtaggatg
      421 tatggtagat ataaacgaca ccgtttgatt cgcggatacg ttcaatcttg tagtagaatt
      481 gatcgccgcg tagacccaat ttttccaagt aaacaagctt gtttccgcgt tcaattgaaa
      541 gaacagttac cttatcatct ttagcattga agagttcaat atctgaaaac tctacaagct
      601 tgtgtttgcg tgcacgtgaa acgaaggttc cttttccttg ttggcggaca atatagccat
      661 ctttggcaag gtcgtttaag gcgcgaacaa ctgtgataga gctgacatcg tacattgaaa
      721 tgagttctgc ttcagtgtaa aatttatctc cactgctaaa ctgcccagag atgattttat
      781 tttttaattc gtcttttatg tattgatatt tgggaattgc catattttta cctctatttt
      841 ccttctccat agaagatttt accataaaag cgaaaaaaat agtagtcttt tgaataaaaa
      901 attagaataa tagtttgaaa aattaagcga tatagggatt gctcatattt tatcaatgta
      961 ttctatgcaa aattatttta ggtcctatat tccgaattta aagagcgttt gaaatgggtc
     1021 taaaaatgtt tgaaactaat tgaatgtgtg tataatagta aaaatgcagt aaatatcccg
     1081 acaatttcta ttgacaattc aaacagattg gtttataatt aatataacaa caagtgaaag
     1141 cgcaaacttt cgcggtcgga aggtagtttt atgacacgat ttgagatacg agatgatttc
     1201 tatctcgatg gaaaatcatt taagatttta tctggtgcca ttcattattt tagggttcct
     1261 ccagaggatt ggtatcattc gctctataac ttgaaggctc ttggttttaa tacggtagag
     1321 acttatgttg cttggaattt acacgagcct cgtgaaggtg agtttcattt tgaaggtgat
     1381 ctggatttag agaaatttct ccaaatagcg caggatttgg gtctctacgc aattgtgcgt
     1441 ccgtctccat ttatctgtgc ggaatgggaa ttcggtggct taccagcttg gctcttgacc
     1501 aagaacatgc gaattcgctc atccgaccca gcatatatcg aggcagttgg tcgctactat
     1561 gatcagttat tgccaagact ggtgcctcgt ttgttggaca atggtggcaa tattctcatg
     1621 atgcaggttg aaaatgagta tggttcttac ggagaagata aggcttacct gagagcgatt
     1681 cgacagctaa tggaagagtg tggcgtaacc tgtcccctct ttacatcaga tggtccatgg
     1741 cgagctactc tgaaagctgg aaccttaatt gaagaggacc tctttgtaac aggaaacttt
     1801 ggttctaagg caccttacaa cttttcgcag atgcaggaat tctttgatga acatggtaag
     1861 aaatggccac tcatgtgtat ggagttctgg gatggttggt tcaatcgctg gaaagaaccg
     1921 attatcacac gggatcctaa ggaattggca gatgcagttc gagaggtttt ggaacaaggc
     1981 tctatcaatc tttacatgtt ccacggtggt acaaactttg gtttcatgaa tggttgctca
     2041 gctcgaggaa ctttggacct gccacaagtt acgtcttatg attacgatgc ccttctggat
     2101 gaagaaggaa atccaactgc taaatatctt gcagtcaaga agatgatggc aacacatttt
     2161 tcagagtatc cgcagttgga accactctac aaagagagta tggagttgga tgctattcca
     2221 ctagttgaaa aagtttcttt gtttgaaacc ttagatagct tgtcaagtcc tgtagaaagt
     2281 ctctatcctc aaaagatgga ggagctggga caaagttatg gctacctact ttatcgaaca
     2341 gaaacaaact gggatgcaga agaagaaaga cttcgtatca ttgatggtcg agatagggcc
     2401 cagctgtatg tcgatggtca gtgggttaaa actcaatatc agacagagat tggggaagat
     2461 attttttatc aaggtaaaaa gaacgggcta tctaggttag atatcttgat agaaaatatg
     2521 gggcgtgtca actatgggca taagttctta gcggatacgc aacgtaaggg aattcggaca
     2581 ggggtctgta aggatctgca tttcttacta aactggaaac actatccact cccactagac
     2641 aatcctgaga aaattgattt ttcaaaagga tggactcaag gacaaccagc cttttacgct
     2701 tatgacttta cagtcgaaga gccaaaagat acttacctag acttgtctga gtttggtaag
     2761 ggggttgcct ttgtcaatgg gcagaatcta ggacgttttt ggaacgttgg cccaactctc
     2821 tcactttata tccctcattg ctatctcaag gaaggtgcca accgcatcat tatctttgaa
     2881 acagaaggtc aatataaaga agagattcat ttaactcgta aacctacact aaaacatata
     2941 aagggggaaa acttatgaca attgtaggat gccgtattga tggacgtttg atccacggac
     3001 aagtagccaa tctttgggct ggaaaactaa atgtttcacg cattatggtt gtagacgacg
     3061 aagttgtcaa caacgatatt gaaaagagtg gtttgaaact tgcgacacca ccaggtgtga
     3121 aattgagtat tttgccagtt gagaaagctg cagccaatat tcttgctggc aaatacgata
     3181 gccaacgtct ctttatcgtg gctcgtaaac cggaccgctt ccttggtttg gtagaagcag
     3241 gtgtaccact tgaaactctt aatgttggga atatgtctca aacaccagaa actcgttcta
     3301 ttacacgttc tatcaacgta gtagacaagg atgtggaaga cttccacaaa ctggcagaaa
     3361 aaggtgttaa acttactgct cagatggttc caaatgatcc aatttcagac tttttgagct
     3421 tattaaaata ggaaaaaaat ttttaggagg tcattgttat gatacaatgg tggcaaattt
     3481 tacttctcac tttgtactca gcttatcaaa tctgtgatga gttgacgatc gtttcatctg
     3541 caggttcccc tgtatttgct ggtttcatta ctggtttaat catgggagat gtgactactg
     3601 gtttacttat cggtggtaac ttgcaactgt tcgttcttgg ggttggtacc ttcggtggtg
     3661 cttctcgtat cgacgcaact tctggtgcgg ttcttgcgac agccttctct gtttcacaag
     3721 gaattgatgc accgcttgcc attactacaa tcgctgtacc agtagcagct ctcttgactt
     3781 acttcgacgt tcttggtcgt atgactacta ccttcttcgc tcaccgtgtg gatgctgcaa
     3841 tcgaacgctt tgactataaa ggtattgaac gcaactactt gcttggtgcg attccgtggg
     3901 ctctatctcg tgcccttcca gtcttctttg cccttgcttt tggtggtgcc tttgtacaat
     3961 cagtagtaga cttcgttgaa gcctacaaat gggttgcaga tggcttgaca ctcgcaggac
     4021 gtatgcttcc aggtcttgga tttgcaatct tgcttcgtta ccttccagtt aaacgtaatc
     4081 ttcactacct tgctatggga tttggtttga cagctatgtt gactgttctt tactcatatg
     4141 taacaggtct tggtggcgct gttgctggta tcgtaggtac tcttcctgct gaagttgctg
     4201 aaaaaattgg tttcgtgaac aacttcaaag gtttgtctat gattggtatt tctatcgtag
     4261 gtattttcct tgcagtgctt cacttcaaaa atagccaaaa agtagctgta gcagcacctt
     4321 ctacaccatc agaaagtggg gaaatcgaag atgacgaatt ctaattacaa acttacaaaa
     4381 gaagatttta atcaaatcaa caaacgtagc ttgtttactt tccaattagg ttggaactac
     4441 gaacgtatgc aagcttctgg ttacctttac atgatcttgc ctcagttgcg taaaatgtat
     4501 ggtgatggaa ctcctgaatt gaaagaaatg atgaaagttc atactcaatt cttcaatact
     4561 tcgccattct tccatactat tatcgctggt tttgaccttg ccatggaaga aaaagatggt
     4621 gtaggttcaa aagacgccgt taacggtatc aagacaggtt tgatgggacc attcgctcct
     4681 cttggggata caatctttgg ttcacttgta cctgctatca tggggtcagt cgcagcaact
     4741 atggctatcg ctggccaacc ttgggggatc ttcctttgga ttgcagttgc agtagcgtat
     4801 gacatcttcc gttggaaaca gttggaattt gcttacaaag aaggggttaa ccttatcaac
     4861 aacatgcaaa gtaccttgac agctttgatt gacgctgcat ctgtacttgg tgtcttcatg
     4921 atgggtgctc ttgtagcaac agtgattaac tttgaaattt cttacaagtt gccaatcggt
     4981 gaaaagatga ttgatttcca agacatcttg aaccaaatct tcccacgttt gcttccagca
     5041 atctttactg cctttatctt ctggttgctt ggtaagaaag gtatgaactc tactaaagct
     5101 atcggtatta ttatcgtact tgctttggct ctttctgccc ttggtcactt tgcacttgga
     5161 atgtaattcc ttatgactaa atcattaatt ttggtgagcc atggtcgctt ctgtgaggag
     5221 cttagaggta gcacagaaat gattatgggc ccacaagaca acatttacac agtagctctt
     5281 cttccagaag atggcccaga agaatttact gctaaatttg aagctgttat tgaagggttg
     5341 gatgatttcc tagtctttgc ggatcttctc ggtgggacac cttgtaatgt ggtcagtcgc
     5401 ttgatcatgg aaggtcgtga tattgacctt tacgcaggga tgaatcttcc aatggtgatt
     5461 gaatttatca atgcgagcct tacaggcgca gatgcggact acaagagccg tgctgcagaa
     5521 agcattgtga aagttaatga cctgttagcg ggcttcgatg atgacgaaga tgaataatac
     5581 tcttcgaaaa tctcttcaaa ctacgtcaac gtcgccttgc cgtaggtata tgttactgac
     5641 ttcgtcagtt ctatctgcaa cctcaaagca gtgctttgag cagcctgcgg ctagtttcct
     5701 attttagttg gaactcgatt caattcatgt gacaacgtga aaatcgttag agcattttat
     5761 atagaatata catgggaatg gagcttactc ccattcctat atttaataga aaaagaggaa
     5821 ctcaatgcta cattatacaa aagaagactt gctcgaattg ggtgcagaaa tcactacgcg
     5881 tgaaatctac caacagcctg atgtatggag agaagctttt gaattttatc aagcaaaacg
     5941 tgaagaaatt gcagcctttc tacaagaaat cgctgataaa tatgactata ttaaagttat
     6001 cttgacaggt gctgggactt ctgcttatgt gggagatacc ttgctacctt attttaagga
     6061 agtctatgac gaacgcaaat ggaatttcaa tgctattgcg acaacagata tcgttgccaa
     6121 tccagcaacc tatttgaaaa aagatgtggc aactgtcctt gtgtcttttg ctcgtagtgg
     6181 gaactcgcct gaaagtgtgg cgactgttga tttggccaaa tccttggtgg atgagcttta
     6241 tcaagtgacg attacttgtg cagcagatgg taaattggct cttcaagctc acggtgatga
     6301 ccgtaatctc ttgctcttgc aaccagctgt ctctaatgat gctggatttg ccatgacttc
     6361 tagctttacg tctatgatgt tgacagctct cttggtcttt gatcctacag aatttgctgt
     6421 taagtctgaa cgttttgaag ttgtatctag tcttgcccgt aaagttttag acaaggcaga
     6481 agatgtcaaa gagctcgttg atttagactt taaccgtgtc atctatctag gcgctggtcc
     6541 tttctttgga cttgctcatg aagctcagct caagattttg gaattaactg ctggtcaagt
     6601 tgcgaccatg tatgaaagcc cagttggctt ccgtcacggt ccaaaatctc ttatcaacga
     6661 caatacagtt gttttggtct ttggtacaac gacagactac actcgtaagt acgacttgga
     6721 cttggttcgt gaagttgctg gtgaccagat tgctcgtcgt gttgtgcttt tgagtgatca
     6781 agcttttggt cttgaaaatg tcaaagaagt ggcccttggt tgtggcggtg tcttgaatga
     6841 tatttaccgt gtcttccctt acatcgttta tgcccaactc tttgctctat tgacttcact
     6901 caaggtagaa aataaaccag atacaccgtc tcctacaggt acagtaaacc gtgtagtaca
     6961 aggtgtcata attcacgaat atcaaaagta agacagtgtt tatgaattct tgacaagagg
     7021 atttgtaaat tatcagataa accatagatt gtcagtacgc tttctatggt ttgtttgctt
     7081 gagagaaata gtaaaaggag aacagaatga aagcatacac agagcgtgta tttggaaatg
     7141 ttgagggcga ggatgtcttg gcctatcgat ttgagacaga cggtggctac caacttgagg
     7201 ttatgactta tggcgcgacc atcttgcgct atgtcgcacc tgacaaggct ggaaattttg
     7261 ccaatgttat cttgggattt gatgactttg atagttatgt aggcaatagt cccaagcatg
     7321 gagcaagtgt aggtcctgta gcgggtcgta ttgcaggtgc gacctttgag ctcaatggta
     7381 agacctatga ccttgaggtt aataatgcta gcaactgtaa tcacagtggt tcaactggtt
     7441 gggattccag cttgtttgaa gttgaagaag taagcgatca tggcttgact ctctacacag
     7501 agcgtacaga tgggacagga gggttccctg gaaatctcaa gatttggatc agttatcact
     7561 tggaagaaac tggtgcctat gaaatcagct acaaggtaac gaccgatcag gatacgctgg
     7621 tcaatccaac caaccacagc tatttcaact tgtctggtga tttcacgcag acgattgacc
     7681 gtcatgtctt ccaactaaac acagagggca tttactcaat cgctcctgac ggtgttcctg
     7741 ccaaaactcc agaagccaac cgtgatgtgg tcaaacacat ctacaatggt accttgttga
     7801 aggatatctt tgcagaagaa gatgagcaaa tccagctggc atcaggtttg gatcacccat
     7861 ttgcccttcc tgtaggccat gacaatgctg gattccttta tgaccaaaat tcaggtcgct
     7921 tcctgctttt caagacagaa gctccttgct ttgtggtcta cacagcaaac tttgtggatg
     7981 aaagtgtcat cataggaggt cagccaatgc tacagcacaa tgggattgct cttgaagcgc
     8041 aagctttacc agatgccatt cacagtgacc ttaaaggcca agtcattctt aaagctggtc
     8101 aaaccttcac cagtaagaca cgttatgaac ttgttgtgaa ataaaaaagc tggtcaaaaa
     8161 gtctttaaaa ttaaaataac gcatattgtc aggtgatgaa aagtttgata atatgcgttt
     8221 tattatgaaa tgatttactt tatattatcc tgaaatggtg ttatttttga gttatctggc
     8281 ttgactttct tgatggaaat tatataatag ttgtaataat tataattaca acgagaaaag
     8341 aggaccattt atgacctatg aatataagag tcacatttat ttggcagaga cagttttaaa
     8401 tgtaaaggat ttggccagtc aaacagcctt ttatcagcaa gttattggtt tagaaatctt
     8461 atctcaaact gagacagagt ccattctagg ccttggtgaa aaagtcttgg tacagctgat
     8521 tcaagcacaa gagagcggag aagtgaggga acattatggt ctttaccatt tggccattct
     8581 cttgcccaca cgcaaggctt tggctgatgt cttgaaacac ctgacagatt tacagattcc
     8641 tcttgtcggc ggtgcagacc atggttacag tgaagctatt tacttggaag atttggaggg
     8701 aaatggcatt gaactctatc gagataagcc agtttccaca tgggatattc gagaagatgg
     8761 acgcattatc ggagtgacgg aggctcttgc ggcgcaggac atttatgagt tgggggaaag
     8821 agtagagccc tttatcctgg cagaaggtac gagaatgggg catattcatc tttccgtcaa
     8881 ggatagtcga aagtccagcc agttttatca aaaggtgtta gggctagagg ataaattcag
     8941 tgtgcctagc gctagttgga ttgcggctgg agattaccat catcatttag cagttaacga
     9001 atggggagga aaaggtctgg cttcgcgtaa gcaaggctta ccaggtttag cctactatgt
     9061 catcgaagtc gcacataaaa aagaactgtt aacgattgcc caacgagcac aagaagttga
     9121 cgcaccaatc aaatggatga catcgagcaa attggaaatc acagactcag atggcatcgt
     9181 gacccgtatt cgtttagcaa ggtaaaatta ggaattttta ataagttata agtattgcta
     9241 gtttgctttt tgaacggtct ttggtaacag aactgcgtga gctggatggg tgagaatttt
     9301 gacaaagaag ctgattagag atataatgaa gaaaaatcga gcaaggaaaa agaaatgaca
     9361 aattcaaagt atattactcg tttgaaacgt tcagagggcc agttgcgtgg gattcaaaag
     9421 atgattgaag gagatcgtga cgcaactgac agcagtgaga tctagtgtag agcgcgtgat
     9481 tgagatgata attaccgaaa atcttactga atgtatcaat cagccactag atgattctga
     9541 agctcaaaag gaacgcttag aaaaggctat ccgatacttg attaaacgga aataaatgaa
     9601 tgttttgaga cgatatgtgc aaaggtctat taactattgg aatagtttaa tgggagtcaa
     9661 aagaagttgt aaaaaatctt taaaattaaa aaaacgcata gtatcaggta ttgaaatgta
     9721 ctgaccccaa aaagttagat tttttctgtc taacttttgg ggtgcagttc ataagaacct
     9781 tggtaatatg cgttttatta tggggagatt tatacttttc gaaaatctct tcaaaccagg
     9841 tcagcttcac cttgccgtag atatggttac tgacttcgtc agttctatcc acaacctcaa
     9901 aacagtgttt tgagctgact tcgtcagttc catccacaac cttaaaacag tgttttgagc
     9961 agcctgcggc taacttccta gtttgcactt taattttcat tgagtattac ttcatcttct
    10021 catgaaattg agtttttgcc cagctcctct tgattattct acttgaccag gccaagcatt
    10081 cataccacct tctacgttgg taacggtgag gccttgggag atgagaaatt ggcaggtaga
    10141 tgcagagcgg actcctcctt gacaaataac atagtattca tggtcaggtt tgagttcttt
    10201 gtagccttgc tctaaggtac ttaatggaag atttttggca cctggtgcat gtcctgcttg
    10261 gaattcatgt gcttcacgga catcgataag ttctagattt tcattttggt attttccata
    10321 aaagtcagcc atgctgatac tagtttccat attctactcc ttctgggtta accattttgt
    10381 atagtgaata agcgccgtca aggttttggg cggtaaatcc tgcttgcttg aggataggct
    10441 ctgcgatata gctgcgcaaa ccactgtggc agctgacgat gtaggcttgt tttttgtcca
    10501 gttcatcagc ttcctccttg acactcggtc agattttgat acaatagtac aaaattagag
    10561 gaggcaggct atgattcaga aacatgcgat tcctatttta gagtttgatg acaatcctca
    10621 ggcggttatc atgcccaatc acgaggggct ggacttgcag ttgccaaaga agtgtgttta
    10681 tgcattttta ggtgaggaga ttgaccgcta tgcgagggaa gtaggggcga actgtgttgg
    10741 cgaatttgtt tctgccacca agacctatcc agtctatgtc atcaactaca agggtgagga
    10801 ggtctgtctg gctcaggctc ctgttggctc cgctccagca gcccagttta tggattggtt
    10861 ggttggctat ggtgtggagc agattatctc tactgggacc tgtggtgtcc tagctgatat
    10921 agaggaaaat gcctttctag tccctgttcg cgctctgcga gatgaaggag ccagttacca
    10981 ctatgtggca ccttctcgtt atatggaaat gcagccagag gctattgctg ctattgagga
    11041 agttttggaa gacagaggga ttccttatga agaagtcatg acctggacga cagacggttt
    11101 ttaccgagaa acggctgaaa aggtggctta tcgtaaggaa gaaggctgtg ctgttgtgga
    11161 gatggagtgt tccgctcttg cggcagtagc tcaattgcgt ggggttctct ggggtgaatt
    11221 gttgttcaca gcagattctc tagcggactt ggaccagtac gacagtcgtg actggggctc
    11281 ggaagctttt aataaggcgc tagaactgag tttagcaagt gttcaccacc tttagttgta
    11341 ctggcaaagg atttgtttta tcataaaatg tctagctcat acttttcaaa aatatgttta
    11401 aacgaggtca ccttcctctt gtcctaggca tgttgaggtt gggaaaaatc tttaaaatca
    11461 gaaaaacgta tcatatcagg tgatgaaaac tttgatacta tgcgttttat gttggtaaga
    11521 tttagagtga gatgaaatga tactcttcga aaatctcttc aaaccaggtc agcttcacct
    11581 tgccgtatag atgttactga cttcgtcagt tctatctgca acctcaaaac agtgttttga
    11641 gcaacctgtg actagctttc taagcgatgc cttggttctc attgcctata atcaaaaaga
    11701 gaaattttct cctgaaaagc atatagagta gctggcgtta aaagctcctg tcttgctttt
    11761 ttgacctata gtcacatcta tcaagtattg ttcttgccta agctatcaat aaaaaggtgg
    11821 cattttttag gcttggtgtt agtagatttt gccttatcct atctaagtca tttcgaactt
    11881 tttatggtac aatggaaaca tgttattcaa attatctaag gaaaaaatag agctaggctt
    11941 atctcgttta tcgccagccc gtcgtatttt tttgagtttt gccttggtca ttttactagg
    12001 ctctcttctt ttgagcttgc cctttgtcca agttgaaagc tcacgagcga cttattttga
    12061 tcatcttttc actgctgtct ctgcagtctg tgtgacaggt ctctcaaccc ttccagtagc
    12121 tcacacctat aatatatggg gccaaataat ctgtttgctc ttgattcaga tcggtggtct
    12181 agggctcatg acctttattg gggttttcta tatccagagc aagcaaaagc ttagtcttcg
    12241 tagccgtgca actattcagg atagttttag ttatggagaa actcgatctt tgagaaagtt
    12301 tgtctattct atttttctca cgaccttttt ggttgagagc ttgggagcta ttttgcttag
    12361 ttttcgcctt attcctcaac ttggctgggg acgtggtctt tttagttcca tttttctagc
    12421 gatctcagcc ttctgtaatg ccggttttga taatttaggg agcaccagtt tatttgcttt
    12481 tcagaccgat ttactggtca atctggtgat tgcaggcttg attattacag gcggccttgg
    12541 ttttatggtc tggtttgatt tggctggtca tgtaggaaga aagaaaaaag gacgtctgca
    12601 ctttcatact aagcttgtac tattgttgac tataggtttg ttgttatttg gaacggcaac
    12661 tactctcttt cttgagtgga acaatgctgg aacgattggc aatctccctg ttgccgataa
    12721 ggttttagtt agcttttttc aaacagtgac gatgcgaaca gctggctttt ctacgataga
    12781 ttatactcag gctcatcctg tgactctttt gatttatatc ttacagatgt ttctaggtgg
    12841 ggcacctgga ggaacagctg ggggactcaa gattacgaca ttttttgtcc tcttggtctt
    12901 tgcacgaagt gagcttctag gcttgcctca tgccaatgtt gcgagacgaa cgattgcgcc
    12961 gcgaacggtt caaaaatcct ttagtgtctt tattatcttt ttgatgagct tcttgatagg
    13021 attgattctg ctagggataa cagccaaagg caatcctccc tttatccacc tcatatttga
    13081 aaccatttca gctcttagta cagttggtgt aacggcaaat ctgactcctg accttgggaa
    13141 attggctctc agtgttatca tgccacttat gtttatggga cgaattggtc ccttgacctt
    13201 gtttgttagc ttggcagatt accatccaga aaagaaagat atgattcact atatgaaagc
    13261 agatattagt attggttaag aaaggaaaga tcatgtcaga tcgtacgatt ggaattttgg
    13321 gcttgggaat ttttgggagc agtgtcctag ctgccctagc caagcaggat atgaatatta
    13381 tcgctattga tgaccacgca gagcgcatca atcagtttga gccagttttg gcgcgtggag
    13441 tgattggtga catcacagat gaagaattat tgagatcagc agggattgat acctgcgata
    13501 ccgttgtagt cgcgacaggt gaaaatctgg agtcgagtgt gcttgcggtt atgcactgta
    13561 agagtttggg ggtaccgact gttattgcta aggtcaaaag tcagaccgct aagaaagtgc
    13621 tagaaaagat tggagctgac tcggttatct cgccagagta tgaaatgggg cagtctctag
    13681 cacagaccat tcttttccat aatagtgttg atgtctttca gttggataaa aatgtgtcta
    13741 tcgtggagat gaaaattcct cagtcttggg caggtcaaag tctgagtaaa ttagacctcc
    13801 gtggcaaata caatctgaat attttgggtt tccgagagca ggaaaattcc ccattggatg
    13861 ttgaatttgg accagatgac ctcttgaaag cagataccta tattttggca gtcatcaaca
    13921 accagtattt ggatacccta gtagcattga attcgtaaag agggatgacc cctctttttt
    13981 gatgcccaag atggcaaata gagacagaag ccccttgtct tctagttaaa agttcttcaa
    14041 aggctggact ttatgataaa atagaaagaa gtgacaagag agagtaatac tcaatgaaaa
    14101 tcaaagatca aactaggaaa ctagctgcgg gctgctcaaa acactgtttt gaggttgtgg
    14161 atagaactga cgaagtcagc tcaaaacact gttttgaggt tgcagataga actgacgaag
    14221 tcagtaacat ctatacggca aggcgacgtt gacgcggttt gaagagattt tcgaagagta
    14281 taagaaaaaa tcagtcccct aaaggagcag attatgaagt tattgtctat cgccatttct
    14341 agctataatg cagcagccta tcttcattac tgtgtggagt cgctagtgat tggtggtgag
    14401 caagttgaga ttttgattat caatgacggg tctcaggatc agactcagga aatcgctgag
    14461 tgtttagcta gcaagtatcc taacatcgtt agagccatct atcaggaaaa taaaggccat
    14521 ggcggtgtgg tcaattgcgg tttggcagag gcttctgggc gctattttaa agtagttgac
    14581 agtgatgact gggtggatcc tcgtgcctac ttgaaaattc ttgaaacctt gcaggaactt
    14641 gagagcaagg gtcaagaggt ggatgccttt gtgaccaatt ttgtctatga aaaggaaggt
    14701 cagtctcgta agaagagtat gagttacgag tcagtcttgc ctgttcggca gatttttgac
    14761 taggaccagg tcggaaattt ctccaaaggc cagtatatca tgatacactc gctgatttat
    14821 cggacagatt tgttgcgtgc tagccagttc taactgcctg aacatacttt ttatgtcgat
    14881 gatctctttg tctttacgcc ccttcagcag gtcaagacca tgtactatct gcctgtcgat
    14941 ttctatcgtt atttgattgg gcgtgaggac cagtctgtca atgagcaagt gatgattaag
    15001 cgcattgacc agcaactcaa ggtcaatcga ctcttggtag accagcttga tttgtcccaa
    15061 gtgagtcatc ctaaaatgcg agaatatctg ctgaatcata ttgaaatcac gacggtgatt
    15121 tccagtaccc tgctcaaccg atctgaaaca gcggagcatc tggcaaaaaa acgccaattg
    15181 tggacctata ttcagcagaa aaatccagaa gtctttcagg ctattcgtaa gaccatgttg
    15241 agccgtttga ccaaacattc tgtcttgcca gatcgcaaac tgtccaatgt cgtctatcaa
    15301 atcaccaaat ctgtttatgg atttaattaa tataagtgtt ttataagagg catttaagaa
    15361 aaattttaac tttttcttag tcctttttaa tttcaggaga ttatactaga gtcatcaaat
    15421 aaagaaagac tctaaggaga atcctatgaa attcaatcca aatcaaagat atactcgttg
    15481 gtctattcgc cgtctcagtg tcggtgttgc ctcagttgtt gtggctagtg gcttctttgt
    15541 cctagttggt cagccaagtt ctgtacgtgc cgatgtggtc aatccgaccc caggtcaagt
    15601 cttacctgaa gagacatcgg gaacgaaaga gggtgactta tcagaaaaac caggagacac
    15661 cgttctcact caagcgaaac ctgagggcgt tactggaaat acgaattcac ttccgacacc
    15721 tacagaaaga actgaagtga gcgaggaaac aaactcttct agtctggata cactttttga
    15781 aaaagatgaa gaagctcaaa aaaatccaga gctaacagat gtcttaaaag aaactgtaga
    15841 tacagctgat gtggatggga cacaagcaag tccagcagaa actactcctg aacaagtaaa
    15901 aggtggagtg aaagaaaata caaaagacag catcgatgtt cctgctgctt atcttgaaaa
    15961 agctgaaggg aaaggtcctt tcactgccgg tgtaaaccaa gtaattcctt atgaactatt
    16021 cgctggtgat ggtatgttaa ctcgtctatt actaaaagct tcggataatg ctccttggtc
    16081 tgacaatggt actgctaaaa atcctgcttt acctcctctt gaaggattaa caaaagggaa
    16141 atacttctat gaagtagact taaatggcaa tactgttggt aaacaaggtc aagctttaat
    16201 tgatcaactt cgctctaatg gtactcaaac ttataaagct actgttaaag tttacggaaa
    16261 taaagacggt aaagctgact tgactaatct agttgctact aaaaatgtag acatcaacat
    16321 caatggatta gttgctaaag aaactgtcga aaaagctgtt aaagataacg ttaaagacag
    16381 tatcgatgtt ccagcagcct acctagaaca agccaagggt gaaggtccat tcacagcagg
    16441 tgtcaaccat gtgattccat acgaactctt cgcaggtgat ggcatgttga ctcgtctctt
    16501 gctcaaggca tctgacaagg caccatggtc agataacggt gacgctaaaa acccagccct
    16561 atctccacta gg
//
LOCUS       DAVLXH010000047        16023 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00028199
            SAMN33607166-rid17955573.denovo.047, whole genome shotgun sequence.
ACCESSION   DAVLXH010000047 DAVLXH010000000
VERSION     DAVLXH010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607166
            Sequence Read Archive: SRR23725544
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16023)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16023)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721421.1
            Genome Coverage       :: 115x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:42:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,210
            CDSs (total)                      :: 2,161
            Genes (coding)                    :: 2,023
            CDSs (with protein)               :: 2,023
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 73 of 138
            Pseudo Genes (incomplete)         :: 60 of 138
            Pseudo Genes (internal stop)      :: 40 of 138
            Pseudo Genes (multiple problems)  :: 31 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16023
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607166-rid17955573.denovo.047"
                     /strain="AUSMDU00028199"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1349"
     gene            <1..665
                     /locus_tag="VYO11_001642"
     CDS             <1..665
                     /locus_tag="VYO11_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV1596175.1"
                     /translation="IRDHFLKYDRAVRCRVKIITMDMFSPYYGLAKQLRFHIVQHLSR
                     AMSRVRVQIMNQFHRKSHEYKAIKRYWKLIQQDSRKLSDKRFYRPTFRMHLTNKEILD
                     KILSYSEDLKHHYQIYQLLLFHFQNKDLEKFFGLIEDNLKQVHPIFQTVFKTFLKNKE
                     KIVNALQLPYSNAKLEATNNLIKLIKRNAFGFRNFENFKKRIFIALNIKKERTNFVLS
                     RA"
     gene            complement(764..2386)
                     /gene="groL"
                     /locus_tag="VYO11_001643"
     CDS             complement(764..2386)
                     /gene="groL"
                     /locus_tag="VYO11_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166362.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HEV1596176.1"
                     /translation="MSKEIKFSSDARSAMVRGVDILADTVKVTLGPKGRNVVLEKSFG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     IKNVTAGANPIGIRRGIETAVAAAVEALKNNAIPVANKEAIAQVAAVSSRSEKVGEYI
                     SEAMEKVGKDGVITIEESRGMETELEVVEGMQFDRGYLSQYMVTDSEKMVADLENPYI
                     LITDKKISNIQEILPLLESILQSNRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITEDLGLELKDATIEALGQAARVTVDKDSTVIVEGA
                     GNPEAISHRVAVIKSQIETTTSEFDREKLQERLAKLSGGVAVIKVGAATETELKEMKL
                     RIEDALNATRAAVEEGIVAGGGTALANVIPAVATLELTGDEATGRNIVLRALEEPVRQ
                     IAHNAGFEGSIVIDRLKNAELGIGFNAATGEWVNMIDQGIIDPVKVSRSALQNAASVA
                     SLILTTEAVVANKPEPVAPAPAMDPSMMGGMM"
     gene            complement(2402..2686)
                     /gene="groES"
                     /locus_tag="VYO11_001644"
     CDS             complement(2402..2686)
                     /gene="groES"
                     /locus_tag="VYO11_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HEV1596177.1"
                     /translation="MLKPLGDRVVLKIEEKEQTVGGFVLAGSAQEKTKTAQVVATGQG
                     VRTLNGDLVAPSVKTGDRVLVEAHAGLDVKDGDEKYIIVGEANILAIIEE"
     gene            complement(2956..3351)
                     /locus_tag="VYO11_001645"
     CDS             complement(2956..3351)
                     /locus_tag="VYO11_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEV1596178.1"
                     /translation="MYNKVILIGRLTSTPELHKTNNDKSVARATIAVNRRYKDQNGER
                     EADFVNMVLWGRLAETLASYATKGSLISVDGELRTRRFEKNGQMNYVTEVLVTGFQLL
                     ESRAQRAMRENNAGQDLADLVLEEEELPF"
     gene            complement(3429..4190)
                     /locus_tag="VYO11_001646"
     CDS             complement(3429..4190)
                     /locus_tag="VYO11_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HEV1596179.1"
                     /translation="MAKNVVITGATSGIGEAIARAYLEQGEDVVLTGRRIDRLEILKS
                     EFAVSFPNQTVWTFPLDVTDMVMVKTVCSDILETIGRIDILVNNAGLALDLAPYQDYE
                     ELDMLTMLDTNVKGLMAVTRCFLPAMVKANQGHIINMGSTAGIYAYAGAAVYSATKAA
                     VKTFSDGLRIDTIATDIKVTTIQPGIVETDFSTVRFHGDKERAASVYQGIEALQAQDI
                     ADTVVYVTSQPRRVQITDMTIMANQQATGFMVHKK"
     gene            complement(4223..4849)
                     /locus_tag="VYO11_001647"
     CDS             complement(4223..4849)
                     /locus_tag="VYO11_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 and tRNA-binding domain-containing
                     protein"
                     /protein_id="HEV1596180.1"
                     /translation="MIFTYNKEHVGDVLMVIVKNSGDAKLNVERKDKVARVFLKENGE
                     TVAWNIFEVSSLFEIAERGQVFLSDEQVARLNQELQAEGFTEEIVNDKEPKFVVGEIV
                     EMVAHPDSDHLNICQVAVASDKIVQIVAGAPNARVGLKTIVALPGAMMPKGNFIFPGE
                     LRGEKSFGMMCSPRELHLPNAPQKRGVLELSEDQVVGTPFDPAKHWTA"
     gene            complement(4865..5182)
                     /locus_tag="VYO11_001648"
     CDS             complement(4865..5182)
                     /locus_tag="VYO11_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000615765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HEV1596181.1"
                     /translation="MIQPASLEELASLVEKDGKKVFLFVADWCGDCRYIYPALPEIEE
                     SNPEFTFIRVDRDQYIDLAKLWDVYGIPSLVVLEKDKEIGRFVNRDRKSKQQINDFLA
                     GLK"
     gene            complement(5179..5478)
                     /locus_tag="VYO11_001649"
     CDS             complement(5179..5478)
                     /locus_tag="VYO11_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001013971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4651 domain-containing protein"
                     /protein_id="HEV1596182.1"
                     /translation="MNGMKAKKMWMAGLALLGIGSLALATKKVADDRKLMKTQEELTE
                     IVRDHFSDMGEIATLYVQVYESSLESLVGGVIFEDGRHYTFVYENEDLVYEEEVL"
     gene            complement(5815..6006)
                     /locus_tag="VYO11_001650"
     CDS             complement(5815..6006)
                     /locus_tag="VYO11_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000291825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein"
                     /protein_id="HEV1596183.1"
                     /translation="MYYSVDDVVSNAFKKRMILDSFFAFNCSGTMKVSTWVYDKGEWY
                     YVSSSGSMIANDWVKDNGK"
     gene            complement(6167..6841)
                     /locus_tag="VYO11_001651"
     CDS             complement(6167..6841)
                     /locus_tag="VYO11_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1596184.1"
                     /translation="MKKKAFGIVLLVLAAWILLQGNFGIPSLDGKIWPLLGIVFFAYK
                     SIESILRRHLTSAVFTGLLAIIIANYAYDLLPVTNHSLIWASILVVLGVGYLTHSSKF
                     WNEKKWWYNGKKTVVTDKEVAFGSGTFYKQDQDLVDDQVEVAFGDAKIYYDNAEMLGD
                     FATLNIEVAFGNATVYVPQHWRVDLKVETSFGAAKADAPVAPTSKTLTIRGDVAFGKL
                     EIVYVK"
     gene            complement(6847..7293)
                     /locus_tag="VYO11_001652"
     CDS             complement(6847..7293)
                     /locus_tag="VYO11_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1596185.1"
                     /translation="MKLRIEIDGNLEETEIVIKTPTLTDEIADLQRLLQESKAPRLTF
                     YKGTGEYYLDLSEILFFETEGSKIYAHNQKEAYEVRLKLYELEAILPRYFSRVSKSTI
                     VNIRQIYSVDKSFSGTGTISFYQTHKEVHVSRHYQSLLKENLRNMR"
     gene            complement(7407..7910)
                     /locus_tag="VYO11_001653"
     CDS             complement(7407..7910)
                     /locus_tag="VYO11_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HEV1596186.1"
                     /translation="MKNYQEWYRNIRSRLTSRPILLFLLRSFNRLMTVAMPLVYLILL
                     VTTYLQLGLGQQVGVYVLIPASGFVALSLFRKKINHPRPYETWNICPLLDKDSSGRSM
                     PSRHVFSATIISMACLHASLPIGLVCLIFSALLGLVRVLGGVHYPKDVLVGYACGLVW
                     GFLFFLF"
     gene            complement(7907..8269)
                     /locus_tag="VYO11_001654"
     CDS             complement(7907..8269)
                     /locus_tag="VYO11_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 domain-containing protein"
                     /protein_id="HEV1596187.1"
                     /translation="MSQKLYNMKFAAVYLALIAKVERKGGKAESVHQVTSWLTGYEVS
                     DVLACLDRDVTYGDFFRQAPYYVPERIAITGKICGVRIEEIDDPLMQEIRRLDKLVDW
                     LAKGKTSQQVLEKYEKHK"
     gene            complement(8335..10194)
                     /locus_tag="VYO11_001655"
                     /pseudo
     CDS             complement(8335..10194)
                     /locus_tag="VYO11_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001850459.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein/permease"
     gene            complement(10211..10680)
                     /locus_tag="VYO11_001656"
                     /pseudo
     CDS             complement(10211..10680)
                     /locus_tag="VYO11_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360543.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
     gene            complement(10804..11520)
                     /locus_tag="VYO11_001657"
     CDS             complement(10804..11520)
                     /locus_tag="VYO11_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV1596188.1"
                     /translation="MGRKWANIVAKKTAKDGANSKVYAKFGVEIYVAAKKGDPDPESN
                     SALKFVIDRAKQAQVPKHIIDKAIDKAKGNTDETFTEGRYEGFGPNGSMLIVDTLTSN
                     VNRTAANVRAAFGKNGGNMGASGSVSYLFDNKGVIVFGGEDADAVFEQLLEADVDVDD
                     VEAQEGTITVYTAPTDLHKAIVALRESGIEEFQVTELEMIPQSEVELSGEDLETFEKL
                     YSVLEDDEDVQKIYTNVDGF"
     gene            complement(12401..13816)
                     /gene="ply"
                     /locus_tag="VYO11_001658"
     CDS             complement(12401..13816)
                     /gene="ply"
                     /locus_tag="VYO11_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cholesterol-dependent cytolysin pneumolysin"
                     /protein_id="HEV1596189.1"
                     /translation="MANKAVNDFILAMNYDKKKLLTHQGESIENRFIKEGNQLPDEFV
                     VIERKKRSLSTNTSDISVTATNDSRLYPGALLVVDETLLENNPTLLAVDRAPMTYSID
                     LPGLASSDSFLQVEDPSNSSVRGAVNDLLAKWHQDYGQVNNVPARMQYEKITAHSMEQ
                     LKVKFGSDFEKTGNSLDIDFNSVHSGEKQIQIVNFKQIYYTVSVDAVKNPGDVFQDTV
                     TVEDLKQRGISAERPLVYISSVAYGRQVYLKLETTSKSDEVEAAFEALIKGVKVAPQT
                     EWKQILDNTEVKAVILGGDPSSGARVVTGKVDMVEDLIQEGSRFTADHPGLPISYTTS
                     FLRDNVVATFQNSTDYVETKVTAYRNGDLLLDHSGAYVAQYYITWNELSYDHQGKEVL
                     TPKAWDRNGQDLTAHFTTSIPLKGNVRNLSVKIRECTGLAWEWWRTVYEKTDLPLVRK
                     RTISIWGTTLYPQVEDKVEND"
     gene            complement(13827..14159)
                     /locus_tag="VYO11_001659"
     CDS             complement(13827..14159)
                     /locus_tag="VYO11_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1596190.1"
                     /translation="MYICIDNSMTKNKELVKNQTFKPALLTRRLVKNFMIEEPDLARN
                     PFTRPTLIDLDKVFMLDNTVIPTSYLARRRRNVSEELYEEILDYLVQPRLISLNKSEF
                     MQLNPGTY"
     gene            complement(14230..14838)
                     /locus_tag="VYO11_001660"
     CDS             complement(14230..14838)
                     /locus_tag="VYO11_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1596191.1"
                     /translation="MSQSSYLSPLLWLKKEADKEKMSATQCQIFFFYYQMFELLFARE
                     SDMKDLCLGTKGFYFSQLEKNLLSGVSRFLKNLEGKVTLKANQEVSARKALFLALTTS
                     QSDWQELAPVFDFYQTIGRLENPSLLSSQDRQHLMWIYQSALEKDYIVKVIGDKHFVL
                     KRQDATKLTARQTQTLEILSQSEDLVNPVYVTLGEKGVLLLD"
     gene            complement(14851..15309)
                     /locus_tag="VYO11_001661"
     CDS             complement(14851..15309)
                     /locus_tag="VYO11_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000186958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4231 domain-containing protein"
                     /protein_id="HEV1596192.1"
                     /translation="MTPEEMYLTERLDVQIAHFLKKSVQHRRRYKVLKITEIVAGFLI
                     AVFCAIPMPGDRYRLISVALSSLGLLCEGIINLYNAKENWISYQKTAQLLEKEKFLYQ
                     CQTEKYAGKTKAFALFVKTCEGLISEEINQWESIQSKEVAASADAPVKKE"
     gene            15434..15833
                     /locus_tag="VYO11_001662"
                     /pseudo
     CDS             15434..15833
                     /locus_tag="VYO11_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         4734 a         3648 c         2883 g         4758 t
ORIGIN      
        1 tcatccgaga tcactttctt aaatatgata gagccgtccg atgtcgcgtc aaaattatta
       61 ctatggatat gtttagccct tactatggct tggctaaaca gcttcgcttt cacattgtac
      121 aacatcttag ccgtgctatg agtcgtgtgc gtgtccaaat catgaatcag tttcatcgaa
      181 aatcccatga atacaaggct atcaaacgtt actggaaact catccaacag gatagtcgta
      241 aattgagcga taaacgtttt tatcgcccta cttttcgcat gcacttaaca aataaagaaa
      301 ttcttgacaa gattttaagc tattcagaag acttgaaaca ccactatcag atctatcaac
      361 tcttactttt tcactttcag aacaaagacc ttgagaaatt tttcggactc attgaggaca
      421 atctgaagca ggttcatcct atttttcaga ctgtctttaa aacctttcta aagaacaaag
      481 aaaaaatcgt caacgctctt caattacctt attccaacgc aaaattggaa gcgaccaata
      541 atctcatcaa acttatcaaa cgaaacgcct ttggatttcg gaactttgaa aacttcaaaa
      601 aaaggatttt tatcgctctg aacatcaaaa aagaaaggac gaattttgtc ctttctcgag
      661 cttagctgac ttcaacccac tacagttgac aaagagccta taaaaagaag ggttagtcat
      721 tccctccttt tgtgtttttt ataagttgtt ttctatagaa agcttacatc atcccgccca
      781 tcatacttgg atccattgct ggagctgggg ctactggttc tggtttattg gctacgactg
      841 cttctgttgt caaaatcaag ctggctacag atgctgcatt ttgtagggct gaacgactca
      901 ctttaactgg atcaatgata ccttgatcaa tcatgttaac ccactcgcca gttgctgcgt
      961 tgaatcctat accaagctca gcatttttca aacgatcgat aacgatagat ccttcaaatc
     1021 ctgcattgtg agcaatttga cgaacgggtt cttccaaagc acggagaaca atattacgtc
     1081 ctgttgcttc atctcctgtc aattccaaag tagcaacagc tggaatcaca ttggcaagag
     1141 ctgttccacc acctgcaaca ataccttctt caacagctgc acgagtagcg ttgagggcat
     1201 cttcaatgcg gagtttcatt tctttcaact cagtttcagt tgcggctccg accttaataa
     1261 ccgctacacc acctgacaat ttggccaagc gttcttgcaa tttttcacgg tcaaattcag
     1321 aagttgtagt ttcgatttga gacttgataa ccgcaacacg gtgagaaatc gcttcaggat
     1381 ttcctgcacc ttctacaata accgtgctat ctttgtccac ggtcactctc gctgcttgac
     1441 caagagcttc aattgtcgca tctttcaact caagaccaag gtcttctgtg ataactgttc
     1501 cgcctgttaa gatggcgata tcttcaagca tagctttgcg acggtcacca aaaccaggtg
     1561 ccttgactgc tactacgttg aaggttccac gaattttgtt caaaacaaga gttggaagag
     1621 cctcgccatc cacatcatcc gcaataatca agagtggacg attgctttgg agaatgcttt
     1681 ccaaaagtgg caagatttct tggatattgg aaattttctt gtctgtaatc aaaatgtacg
     1741 gattttcaag gtcagccacc attttttcgc tatcagtcac catgtactgt gaaaggtaac
     1801 cacggtcaaa ctgcattcct tctacgactt caagctctgt ttccatacca cgtgactctt
     1861 cgatggtgat gacaccgtct ttgccaactt tttccattgc ttcagagatg tactcaccaa
     1921 ctttttcaga acgagaagat acggctgcaa cttgagcgat agcttcttta ttggcaacag
     1981 ggatggcgtt gtttttcaaa gcttcaactg ctgcggcaac tgctgtttca atcccacgac
     2041 gaataccgat tggatttgca cctgctgtga cgtttttgat tccttcacgg acgattgctt
     2101 gggtcaaaac agttgcagtt gtagttccat cacctgcgat atcattggtt tttgaagcca
     2161 cttctgatac caatttggca cccatatttt caaaatggtc ttctaattca atttctttgg
     2221 caatagtcac accgtcattg gtaatcaatg gtgagccaaa tgatttttca agaacgacat
     2281 tgcgaccttt tggtcccaag gttactttaa cagtgtctgc aaggatatcg acaccacgga
     2341 ccatagctga acgggcatct gatgaaaatt taatttcttt tgacatactt actttctcct
     2401 tctattcttc aatgattgcc aagatgttag cttcgcctac gatgatgtac ttttcatcgc
     2461 catctttgac atcaagacct gcgtgggctt caactaagac acggtctcca gttttaacac
     2521 ttggagcaac caagtcaccg ttcaaggtac gaacaccttg tccagtagcc acaacttggg
     2581 ctgttttggt tttttcttgg gctgaacctg cgagaacaaa gcccccaacg gtttgttctt
     2641 tttcttctat ttttaagacc acacggtccc ctaatggttt caacatctga tttcctccat
     2701 aatgagatag atattattag cactctttat acctgagtgc taattcatag ttctattgta
     2761 tcacttagtc agaaataatc aagaaaaaag tctgactttc tcaagataaa aagcctgaga
     2821 ccaactcaga ctttttaatg tttatactca atgaaaatca aagagcaaac taggaagcta
     2881 gccgcaggct gctcaaagca ttgctttgat gttgtggata aagctaacgt ggtttgaaga
     2941 gattttcgaa gagtattaaa atggcaattc ttcctcttcc aagactaaat ctgccaaatc
     3001 ttggcctgca ttattttcac gcatagcacg ttgggcacga ctttccaaga gttggaatcc
     3061 tgtcacaagg acttcggtta cataattcat ctgaccattt ttctcaaagc gacgggtacg
     3121 caattctcca tcaacggaaa tgagactacc tttggttgcg tagcttgcca aagtttctgc
     3181 tagtctgccc catagaacca tattgacaaa atcagcttca cgttcaccgt tttggtcttt
     3241 gtaacgacgg ttgacagcga tagttgctcg cgctactgac ttgtcattgt tggttttgtg
     3301 caattctggt gtagacgtta aacgtccaat caagataact ttattataca tattttcttc
     3361 ctcctactta tctattcgta ggaaatcaaa aaaagttaca gaaatttgta acttttcgag
     3421 aaaatttttt attttttatg aaccatgaaa cctgtcgcct gttgattggc cataatggtc
     3481 atatctgtaa tctgaacacg acgaggttga ctagtcacat agactactgt atctgcaata
     3541 tcctgagctt gcaaagcttc tattccttgg taaacggacg cagctcgttc tttatcacca
     3601 tgaaaacgca ctgtagaaaa atctgtttcg acaattccag gctgaatggt cgtcaccttg
     3661 atatccgttg cgatggtatc aattcgcagt ccatctgaaa aggtcttaac tgccgccttg
     3721 gtggctgagt aaacagctgc accagcatag gcataaattc ctgcggttga ccccatattg
     3781 ataatatgac cttgattggc ttttaccatt gctggcaaga aacagcgagt gactgccatc
     3841 aaacctttga cattggtatc caacatggtc agcatatcca actcttcata gtcttgatag
     3901 ggagctaagt caagagccag tccggcgttg ttgaccaaga tatcaatcct ccctatcgtt
     3961 tctagaatat cagagcaaac agtcttcacc atgaccatat ccgtcacatc tagtggaaaa
     4021 gtccagacgg tttgatttgg aaagcttact gcaaactccg acttgaggat ttctaatctg
     4081 tctatccgtc gtcctgttag aacgacatcc tcaccctgct ccagataagc acgcgcaatc
     4141 gcttcaccga ttcctgaggt tgctcccgta atcactacat tttttgccat cttatttcct
     4201 tctatcagat gctgacaagt tcctaggcag tccagtgttt cgctgggtcg aacggtgttc
     4261 cgacaacttg gtcttctgat aattcaagca ccccacgttt ttgcggagca tttggcaaat
     4321 gcaattcacg aggactacac atcatcccaa aactcttttc accacgaagt tcgcctggga
     4381 aaatgaaatt cccttttggc atcatggcac caggaagagc cacaatggtt ttcaacccaa
     4441 cacgcgcatt aggtgctcct gcaacgattt gcactatctt gtcacttgcg actgcaactt
     4501 ggcagatgtt gaggtggtca ctgtctggat gagctaccat ctcgacaatt tcaccaacaa
     4561 caaacttagg ttccttatca ttaacaattt cttctgtaaa accttccgcc tgtaattctt
     4621 ggttcaaacg agcgacttgc tcatctgata aaaagacttg accgcgctct gcaatttcaa
     4681 acaagctcga aacctcaaaa atgttccaag ctactgtttc cccattttct ttgaggaaaa
     4741 cacgggctac cttgtctttg cgttccacat tcagtttagc atctccgcta tttttcacga
     4801 tgaccataag gacatcaccg acatgttctt tgttatatgt aaaaatcatt gtttcctttt
     4861 tctcctattt caatcctgct aaaaaatcgt taatttgttg cttgctttta cggtcgcgat
     4921 tgacaaaacg accgatttcc ttgtcctttt ctagaacaac aaggctaggg attccatata
     4981 catcccagag tttggccaaa tctatatact ggtctctatc cactcgaata aaggtaaact
     5041 ctggattact ctcctcaatt tctggtaagg caggatagat ataacggcaa tcgccacacc
     5101 agtccgccac aaaaaggaag accttcttac cgtctttttc tactaaagat gccaattctt
     5161 ctaaacttgc tggctgtatc ataagacttc ctcctcatag actaggtctt cattttcata
     5221 gacaaaggta taatgacgac catcctcaaa aatgacgcca ccaaccaagc tctccagact
     5281 gctttcgtaa acttgaacat agagggtcgc aatttccccc atgtcggaaa aatggtctcg
     5341 cacaatctct gtcaactctt cctgagtctt catgagctta cggtcatctg caactttttt
     5401 cgtggcaaga gcaaggcttc cgatacctag cagagccaag cctgccatcc acattttttt
     5461 agctttcata ccattcattt taacacaaaa aaggcttcag gacaaatgag gaagcagcag
     5521 aaaagcaagt aaaaagcctc ttcctttaag gaaaaggact tcttatactc aatgaaaatc
     5581 aaagaccaaa ctaggaagct agccgcaggc tgctcaaagc actgctttga ggttgtagat
     5641 agaactgacg aagtcagctc aaaacactgt tttgaggttg tggatgaagc tgacgtggtt
     5701 tgaagagatt ttcaaagagt attattctta ttgccaggca cctaagttgc caacgtagta
     5761 accatcaggt gtgtaggtat tgcgaagcat cttacctgat gaagccagat aatactactt
     5821 gccattgtct ttgacccaat cattcgcaat catggaacca gaagaactta cataatacca
     5881 ttctcccttg tcataaaccc aagtactgac tttcatggtt cctgagcaat taaaggcaaa
     5941 aaaactgtcc aatatcattc gttttttaaa agcatttgac actacatcat ctacgctgta
     6001 gtacatagat acatcaaacg taaaagccaa aatatcgaaa aatatacaac ttttaaaggc
     6061 agcatttcat tttttaaagt ctaacaacca tagaactgaa atcagagcaa ggcatcaatt
     6121 tcctactctt agtacgtcta ttttgatggt tgaagtgaag atttttttat ttaacgtaga
     6181 caatttccaa cttcccaaaa gccacatctc cacggatagt caaggttttg ctggttgggg
     6241 ctacaggagc gtcagcctta gctgcaccaa aggaggtttc tactttcaaa tctacacgcc
     6301 agtgttgtgg aacatagacg gttgcatttc cgaaggccac ttcaatattt aaagttgcaa
     6361 aatcacctag catctctgca ttatcatagt agattttagc atccccaaaa gcgacttcca
     6421 cttggtcatc tacgagatct tgatcttgct tatagaaggt cccgctacca aaagcgactt
     6481 ccttatccgt gacgactgtt tttttcccat tgtaccacca ttttttttca ttccagaact
     6541 tacttgaatg cgtcagataa ccaacaccaa gtaccaccaa gatgctagcc caaataagag
     6601 aatgattggt aactggtaac aagtcataag cgtaatttgc aatgatgatc gccagtaaac
     6661 ctgtaaaaac tgccgaagtg agatgacgtc taaggatgga ctcaatggac ttataagcaa
     6721 aaaaaacaat acctagtaaa ggccatattt taccatccaa agaaggaatt ccaaaattcc
     6781 cttgcagcaa gatccaagct gctaaaacca ataaaacaat accaaatgct ttctttttca
     6841 tgttttttac ctcatgtttc ttagattttc ttttaggagg gattggtaat gccgtgacac
     6901 atgaacctcc ttgtgggttt gataaaagga aatggtgccc gttcctgaaa aggacttgtc
     6961 caccgaatag atttgccgaa tattaacgat cgttgacttg gatactcgac taaaatagcg
     7021 aggaaggata gcctccaact catagagctt gaggcgaacc tcataagctt ccttctggtt
     7081 atgagcgtag atcttgctcc cttctgtttc aaagaagaga atttctgaca ggtctagata
     7141 atattcacct gtccccttgt aaaaagtcaa cctcggagcc tttgactctt gcaagagccg
     7201 ttgcaagtct gcaatttcat ctgtcaaagt gggggtcttg atgacaattt cagtctcctc
     7261 taaattgccg tcaatctcaa ttcgtaactt catcacatct cctttctgac tctactatat
     7321 caaagctaag ttaggaatac aagggcaaaa aagcaagtgg tcaatttgaa gcagtaagtg
     7381 gttgtaggac tagcttaact tacatgtcag aataggaaga aaaggaatcc ccacaccaaa
     7441 ccacaagcat agccaaccaa gacatccttg ggataatgaa caccccctaa aaccctcacc
     7501 aaccccagca aagctgaaaa gatcaagcat actaagccaa taggtagact agcatgcaga
     7561 caggccatgg agatgatagt tgccgaaaag acatggcgac tgggcatcga ccgtcccgaa
     7621 ctatccttat caagaagggg acagatattc caagtttcat aaggtctcgg gtgattgatt
     7681 ttcttacgaa acagggacaa ggccacaaaa cctgatgcag gaataagcac ataaacccca
     7741 acttgctgac caagtcctag ttgcaggtaa gtggtgacta gcaagatcag atagaccagg
     7801 ggcatggcga ctgtcatcaa acgattgaaa ctgcgtaata ggaataaaag aattggacga
     7861 ctagttagtc tggatctgat atttcgatac cattcttgat aatttttcat ttatgcttct
     7921 catacttttc tagaacttgt tgagatgttt tccccttggc aagccaatcc actagcttgt
     7981 ccaagcgacg tatttcctgc atcagaggat catcaatttc ctcaatacgg acaccgcaaa
     8041 tcttccctgt aattgcaatt cgttcaggga cataatatgg tgcttgtcga aaaaaatctc
     8101 cgtaagtaac atccctatcc agacaagcaa gaacgtcact cacttcatac cctgtcaacc
     8161 aactggtcac ttggtgaact gactctgcct ttccaccctt tcgctcaact tttgcaatca
     8221 aggctaagta gacagcagca aatttcatat tgtataattt ctgactcata cttctctctt
     8281 tctatgtgta ctagtataaa taagaaaaag aaggtcgtca agccttcttt tgatttattc
     8341 ttctgcttca tcttctgtaa attgactatt gtacaagtca gcgtagaagc caccttgcgc
     8401 catcagttcc tcatagttgc cttgctcgat gatatttcca tctttcatga ccaagatcaa
     8461 gtctgcattt cggatggttg acaagcggtg ggcaatgaca aaggatgtgc gtccttccat
     8521 caaacggtcc atggcttttt ggatcaattc ctctgtccgt gtgtcaacag aagaagtcgc
     8581 ctcatccaaa atcaaaagcg gtgcatcctt aagaagggca cgagcaatag tcaatagttg
     8641 tttttgtctt acagacaagg tcacggtgtc atccaagatg gtatcatagc catctggcaa
     8701 ggtcataata aagtggtgaa ttcccacagc cttactagct tccatcattc gttcatcact
     8761 aatccctatt tgattataga tgagattgtc tcgaatagtt ccttcaaaga gccaggtatc
     8821 ctgcaagacc attgaaaagg catcatgcac ttctgaacgc gtcatagcct tggtatccac
     8881 accatcaatg cgaatacttc ccttatcaat ctcatagaat ttcatcaaaa gattgacaat
     8941 ggttgtctta ccagccccag tcggcccaac aatggcaacc ttttgaccag catgagctgt
     9001 cgcagagaag tcatagtctt gaacattgac accgtccacc agaatttctc ctggtgacac
     9061 gtcgtagaaa cgtggaatca gattgaccag agttgattta ccagaacctg ttgacccaat
     9121 aaaggccact gtttgaccag tttctgcttt aaagctaaca tgttcaataa ctgcctccga
     9181 atttgccgca tagcggaagg tcacatcctt aaactcgacc tgacctttga agttttcatc
     9241 agtcagctgc acttgaacag ggttttggat agaagaatgc aaatctaaaa cttgattaat
     9301 ccgcttagca gagaccatag ttcggggaag aacgatgaag agtgctccca tgagaaggaa
     9361 gcccatgaca acctacatgg cataagacat gaaaacaatc atgtcactaa agaaaggcag
     9421 acgcgctatc ggagcagcgt cgttaatcac ataggcccca atccagtaaa tcgccacact
     9481 caaaccactt gaaatcccca tcatgatagg attcaaaata gccataagac ggttgacaaa
     9541 caaattttaa cgggtcaatt catcatttac tgctgcaaat ttttcatttt gataatcctc
     9601 tgcattgtag gcacgaacga cacgaatacc tgttaaactc tcacgagtga tactgttcag
     9661 tttatctgtc agcccctgaa tcaaggactg ttttggaaag gctagcgtca tcaaaacggt
     9721 cgtcatcagg acgttgacaa tcactgccac aagtacggcc cagagccagt attctgaatg
     9781 acctaaaatc ttcccaatag cccagatagc cataattgga ccacacgtta ccacttgcaa
     9841 gtccatagta atcaacattt gaacttgagt aatgtcattg gtagtacgca tcaagaggct
     9901 aggaattgaa aatttcttaa tctctgtctg cgagtaatcc aaaactcggt taaaaatatc
     9961 acttctcagc ctactagtat aagaagccgc cactcgggat gcaaaaaatc caactgcaac
    10021 tacggacaag aaggcaagaa agggcattcc catcatcatg cttgccggct gccacaactc
    10081 atctaaatta gttccttgac tacctagcaa atccgtaatt ttcgagatat aggtcggcac
    10141 ttccaactct agatagaccg aaaagcaagt aaagagaatg gctagtaaaa tcatccccca
    10201 ttcttttcta ctaattcttt tggctaattt ctttattctc tcctcctatt cccttgatat
    10261 ttgcctgtag ttgaccgaga actttctcaa aaatcagtaa ttcatcttca tcaatgtctt
    10321 ccatcaactg cttgtctatg cgttcaaaaa agccttaacc tgttgcatct gagaacgtgc
    10381 tttgtccgtc agacgaacaa acttagcccg cttatcaaca ggactcgcct ccaattccac
    10441 caaaccattt tgcactatac gcttaaccag attactagca acagacttgg taatattgag
    10501 ttcctgctcg atatctttaa tcaagaccaa gtcttggttt ttctcgcgat tatccaaaaa
    10561 acgcacaacc tgaccttgcg gcccacccat aaattcaatg ccgcaacgtt tggcttcctt
    10621 ttgcaccatc aggtaaattt gatgaccaaa acgcttaaag actaacatcg gtttatccat
    10681 aatctccccc ttctaaataa aaatagttct ctggagaata attaaatttc tatgagaact
    10741 attttcttga ttaaaaaaat cccaagtgat tttctcactt aggatcatgt tctataggtt
    10801 agattaaaac ccatctacgt tcgtataaat cttttggacg tcttcgtcgt cttcaagaac
    10861 gctgtaaagt ttttcaaagg tttcaaggtc ttcgcctgac aattccactt ctgactgagg
    10921 aatcatttcc aattcagtca cttggaattc ttcaatacca gactcacgga gagcaacgat
    10981 agccttgtga aggtcagttg gcgctgtgta aactgtgatt gtaccttctt gtgcttctac
    11041 gtcatccaca tccacatccg cttcgagcaa ttgctcaaag actgcgtccg catcttcacc
    11101 tccaaataca ataacacctt tgttgtcaaa aaggtaagaa acagaacctg aagcgcccat
    11161 gtttccgccg tttttaccaa aggctgcacg gacattggct gctgtacggt taacgttaga
    11221 agtcaaagta tccacaatta gcatagagcc atttggccca aaaccttcgt aacgtccttc
    11281 tgtaaaggtt tcgtctgtgt ttcctttggc tttatcaatc gctttatcga taatgtgttt
    11341 tggcacttgg gcttgtttag cacggtcgat aacgaatttc aaagctgagt ttgattctgg
    11401 atctggatca ccttttttag ctgctacata gatttctaca ccaaattttg catatacttt
    11461 agagttagct ccatctttag ccgttttctt ggctacgata ttggcccatt tacgtcccat
    11521 taggaatctc cttttttcac attttaatct ttcttattat aacacaagtt tttttgattt
    11581 tcactagagg aaatggattt tattagcaaa tcaagctagg atagcacttt acctgctaag
    11641 atggtcttgc ctttctatct ttatcaacag acactcatcc acattcaaaa aacaaactag
    11701 accattatct gcaaatagaa agtttcagcc aagtttgaca aagtcagctc aaattactgt
    11761 ttgaagtttg tagatataag cgacaaaaac aatcatactg caccttttgt tgacagtcta
    11821 ctccagacat atcatagttc aagtaaatac tttgaaattc aacagttctt ataggcgcta
    11881 ttgtattcta agaaatcaat agaagagttt ctaagcaaac ctctaatact caataaaaat
    11941 caaagagcaa actagaaagc tagcctcagg ttgctcaaaa cactgttttg aggttgcgga
    12001 tggggctgac atggtttgaa gagattttcg aagagtataa tttacgtgtt cccaagatgg
    12061 agaagttaga ctagtacact ggcacttcta aaacattgct agcaattgat ttgttcatat
    12121 ttaatttcat tttttccata aatgggtatt aaatataaac agcaaaatat ttccgatacg
    12181 tgtcgttctt gaatttccaa tcatctaaaa caagtaaagg ataatcaatc ccctgtatat
    12241 caaggaattg gctacccttt ttactttttt acacattctg tttgatagat tcattttaac
    12301 atcacgagca tactccaatg gaaatcgcta ggcaagagat aaactttcag atatccgcag
    12361 agagatcatc gcctcttttt gtcgcaagca ttctcctctc ctagtcattt tctaccttat
    12421 cttctacctg aggatagaga gttgttcccc aaatagaaat cgtccgctta cgcactagtg
    12481 gcaaatcggt tttttcataa accgtacgcc accattccca ggcaagcccg gtacactctc
    12541 taattttgac agagagatta cgaacattcc cttttaaagg aatactagtg gtaaagtgag
    12601 ccgttaaatc ctgcccattt ctgtcccaag ccttaggagt caagacttcc ttaccttgat
    12661 gatcatagga taattcattc caagtaatat aatattgggc aacataggca ccactatgat
    12721 ccagcagtaa atctccgttt ctgtaagctg taaccttagt ctcaacatag tctgtactat
    12781 tttgaaaggt cgcaactaca ttgtcacgta aaaaagaagt tgtataggaa atcggcaagc
    12841 ctggatgatc tgctgtaaag cgactgcctt cttgaatcaa gtcctctacc atatccacct
    12901 tgcctgttac aactcgggca cccgaacttg ggtcgccccc taaaataacc gccttcactt
    12961 ctgtattgtc caaaatctgc ttccactctg tctgaggagc taccttgact ccttttatca
    13021 aagcttcaaa agcagcctct acttcatcac tcttactcgt ggtttccaac ttgagataga
    13081 cttggcgccc ataagcaaca ctcgaaatat agaccaaagg acgctctgca gaaattcctc
    13141 tctgttttaa atcctctacc gttacagtat cttgaaacac atctcctgga tttttaacag
    13201 catctacgct gactgtataa taaatctgct taaaattaac aatctgaatc tgcttttcgc
    13261 ctgaatggac agagttaaaa tcaatatcaa gagaattccc tgtcttttca aagtcagaac
    13321 caaacttgac cttgagttgt tccatgctgt gagccgtgat tttttcatac tgcattctag
    13381 ctgggacatt attgacctga ccataatctt gatgccactt agccaacaaa tcgtttaccg
    13441 ctccgcgaac acttgaattg ctggggtctt ccacttggag aaagctatcg ctacttgcca
    13501 aaccaggcaa atcaatacta taagtcatcg gagcacgatc gaccgcaaga agagtgggat
    13561 tattctctaa caaggtctca tccactacga gaagtgctcc aggatagagg cgactgtcgt
    13621 tggtagctgt tacagaaata tcacttgtat ttgtcgacaa gctccgcttc tttctttcga
    13681 taacaacaaa ctcatcgggt agctgattac cctctttgat gaaacgattt tcaatacttt
    13741 ctccctgatg ggtcaagagt ttctttttat cgtaattcat agctagtata aagtcattta
    13801 ctgctttatt tgccatcttc tacctcctaa taagttcctg gattgagttg cataaactca
    13861 gacttgttca gcgaaatcag ccgtggttgg actaagtaat ccaaaatttc ctcgtacaat
    13921 tcttctgaga cattgcgtcg ccgtctggct aaataagaag tcggaatgac cgtattatcc
    13981 aacataaata ccttatctaa gtcaatcaag gttggtcttg taaaaggatt acgagctaga
    14041 tccggctctt ctatcataaa gttcttgacc aaacgtctgg tcaagagagc tggtttgaag
    14101 gtctgatttt taaccaactc tttgttttta gtcatgctgt tgtcaataca gatatacata
    14161 tgattcttca cagccaaatc gctactaata gtcggaaaag gcaaataaag agctacaaca
    14221 tctcctctct taatcaagca agagcacccc cttttctcct aatgtaacat agacaggatt
    14281 gaccaagtct tctgattgac tcagaatttc caaagtttga gtttggcgcg ctgtcaattt
    14341 agtagcatct tgtctcttca atacaaaatg cttgtcgcca ataaccttga caatataatc
    14401 cttctccaaa gctgactggt aaatccacat cagatgttgt ctgtcctgag aactcaagag
    14461 agaaggattt tcaagcctcc cgatagtctg ataaaaatca aaaacaggag ctaactcctg
    14521 ccaatctgat tggctagttg tcaaggctag aaaaagggct ttgcgagctg atacttcttg
    14581 gttagccttg agagttactt tcccctccaa gttttttaga aatcgggaaa ctccagaaag
    14641 caaatttttc tctaactgcg agaaataaaa acctttcgtt cccagacata agtctttcat
    14701 gtcgctttct ctagcaaata agagctcaaa catttgatag taaaagaaaa atatctggca
    14761 ctgggtcgcg ctcatctttt ccttatcggc ttcttttttt aaccagagca agggcgacag
    14821 gtagctggat tgagacattt cctctacctc ctactctttt ttaactggag catctgcact
    14881 agctgccact tcttttgact ggatactttc ccactggtta atctcctctg agataagacc
    14941 ttcgcatgtc ttgacaaata gggcaaaagc cttggtcttt cctgcatatt tctccgtttg
    15001 gcattgatag aggaattttt ctttctccag gagttgcgca gttttttggt aagaaatcca
    15061 attttccttt gcattataca aattgataat cccctcacac agcaagccga gactggataa
    15121 ggcaaccgaa atcaaacggt agcgatcacc tggcatagga atagcacaaa agacagctat
    15181 gaggaaacct gccacgattt ctgttatttt taatacctta tagcgcctac gatgttgaac
    15241 gcttttcttt aaaaaatgag ctatctgtac gtctaatcgc tctgtcaggt acatttcttc
    15301 tggcgtcata ttcgtaactc ctttcattta ctttgataac catagtataa catatttgaa
    15361 tatcaaagta tagtaaaaac tggactataa cttattagac tccctgcgaa acaaaatatg
    15421 gtatagtagt tctatgaatt atgaagcaag taaacaatta actgatacac gatttaagcg
    15481 tcttgttggt gttcagcgta ccacttttga agagatgtta gctgtattaa aaacagctta
    15541 tcaaaaaagt cggacaagct ggtaaaatct tggctgacag taattatcaa gggctcatga
    15601 agatatatcc tcaagcacaa actccacgta aatccagcaa actcaagcca ctaacagttg
    15661 aagataaagt ctataaccat gcgctatcta aggagagaag caaggttgag aacatctttg
    15721 ccaaagtaaa aacgtttaaa atgttttcaa caacctgtcg aaatcatcgt aaacgcttcg
    15781 gattacgaat gaatttgagt gctggtatta tcaatcatga actaggattc tagttttgca
    15841 ggaagtctat tttaaaaatt gaagaaatta aaaagagatg atattaggga gaactgattt
    15901 aaaagttctc cctatttaat attattaaat aaaacctaat tatatagtaa actgaaataa
    15961 gatataaaca aatgaattgg agcttagcat ccatttccag caatttttta gaaactacag
    16021 tga
//
LOCUS       DAVLXH010000048        15128 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00028199
            SAMN33607166-rid17955573.denovo.048, whole genome shotgun sequence.
ACCESSION   DAVLXH010000048 DAVLXH010000000
VERSION     DAVLXH010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607166
            Sequence Read Archive: SRR23725544
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15128)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15128)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721421.1
            Genome Coverage       :: 115x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:42:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,210
            CDSs (total)                      :: 2,161
            Genes (coding)                    :: 2,023
            CDSs (with protein)               :: 2,023
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 73 of 138
            Pseudo Genes (incomplete)         :: 60 of 138
            Pseudo Genes (internal stop)      :: 40 of 138
            Pseudo Genes (multiple problems)  :: 31 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15128
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607166-rid17955573.denovo.048"
                     /strain="AUSMDU00028199"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1349"
     gene            140..439
                     /locus_tag="VYO11_001663"
     CDS             140..439
                     /locus_tag="VYO11_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HEV1596193.1"
                     /translation="MKTKKHRLLALALISSFTLLGAASAAVQYPDGGVWTYGEGSGGG
                     WAFSNYYHGKKYHYSSVVSKWDSHSDKGSAPAGKTSEAWIWTKFGEQVSFYYDYD"
     gene            510..2531
                     /locus_tag="VYO11_001664"
     CDS             510..2531
                     /locus_tag="VYO11_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000732428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEV1596194.1"
                     /translation="MKKLFILLSTFFLSFFFAWIIVLRAPQYLYASYDSVTLLRVKKE
                     AQEPTREVFEQELEKFVNSEQSLIARRIVEPSKDGTTHFTYATYGQGTLPKQFQEASQ
                     ESRERSDPLNSYLLLSGSLTKEKLADKLGDLGYKAIADRKTPPYSLAFRMLLNPLILI
                     SLAIFGLSFFALVIITRIKEMRAAGIKLFSGQTLLSIMGHSLSTDIKWLLLSALLSFL
                     GGGVVLFSQGLFYPILLATYGFGISFYLLFLLAISILLMLLYLMSLSYKALVPVIKGR
                     LPLKRLMILTLLCQLVAVFTVGYAVKTGLTSYQRLKELEISKQAWHDRVDYYQISFGL
                     GDRVNDTENQNKWYEFSKEAVEKEQALFVKENLIHFANPQGKNENGETLDTYSPDANV
                     LYVSPSYLDKENVAVNDETRQKLAHLQKGEFGLLLPESLRSQEAELKKVFEERLNYYG
                     KSSEDKDAPLEYEMRAIVSYLPTGQKRFVYNNGESPVSIQYLTDPILVVFTPTSTGDS
                     FISKYVWSINAGKQLFIKGYESGLELLKKAGIYEQVSYLKEGRSVYLTRYNEVQTETA
                     TLILGAIVGIASSLLLFYSVNLLYFEQFRRDILIKRISGLRFFETHAQYMVSQFASFV
                     FGASFFILSSRDLVIGLLTLLVFLASAVLTLYRQAQKESRVSMTIMKGK"
     gene            2533..3174
                     /locus_tag="VYO11_001665"
     CDS             2533..3174
                     /locus_tag="VYO11_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1596195.1"
                     /translation="MIELKNISKKFGSRQLFSDTNLHFEGGKIYALIGTSGCGKTTLL
                     NMIGRLEPYDKGQIIYDGTSLKDIKPSVFFRDYLGYLFQDFGLIESQTVKENLNLGLV
                     GKKLKEKEKISLMKQALNRVNLSYLDLKQPIFELSGGEAQRVALAKIILKDPPLILAD
                     EPTASLDPKNSEELLSILESLKNPNRTIIIATHNPLIWEQVDQVIRVTDLSHR"
     gene            3278..4630
                     /locus_tag="VYO11_001666"
     CDS             3278..4630
                     /locus_tag="VYO11_001666"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HEV1596196.1"
                     /translation="MKVIDQFKNKKVLVLGLAKSGESAARLLDKLGAIVTVNDGKPFE
                     DNPAAQCLLEEGIKVITGGHPLELLDEEFALMVKNPGIPYSNPMIEKALAKGIPVLTE
                     VELAYLISEAPIIGITGSNGKTTTTTMIGEVLTAAGQHGLLSGNIGYPASQVAQIASD
                     KDTLVMELSSFQLMGVQEFQPEIAVITNLMPTHIDYHGSFSEYVAAKWNIQNKMTAAD
                     FLVLNFNQDLAKDLTSKTEATVVPFSTLEKVDGAYLEDGQLYFRGEVVMAANEIGVPG
                     SHNVENALATIAVAKLRGVDNQTIKETLSAFGGVKHRLQFVDDIKGVKFYNDSKSTNI
                     LATQKALSGFDNSKVVLIAGGLDRGNEFDELVPDITGLKKMVILGQSAERVKRAADKA
                     GVAYVEATDIADATRKAYELATQGDVVLLSPANASWDMYANFEVRGDLFIDTVAELKE
                     "
     gene            4632..5690
                     /locus_tag="VYO11_001667"
     CDS             4632..5690
                     /locus_tag="VYO11_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine--N-acetylmuramyl-
                     (pentapeptide) pyrophosphoryl-undecaprenol
                     N-acetylglucosamine transferase"
                     /protein_id="HEV1596197.1"
                     /translation="MKKIVFTGGGTVGHVTLNLLLMPKFIEDGWEVHYIGDKRGIEHQ
                     EILKSGLDVTFHSIATGKLRRYFSWQNMLDVFKVCWGIVQSLFIMLRLRPQTLFSKGG
                     FVSVPPVIAARVSGVPVFIHESDLSMGLANKIAYKFATKMYSTFEQASSLSKVEHVGA
                     VTKVSDQKNPEPDELVDIQSHFNHKLPTVLFVGGSAGARVFNQLVTDHKKELTERYNI
                     INLTGDSSLNELRQNLFRVDYVTDLYQPLMELADIVVTRGGANTIFELLAIAKLHVIV
                     PLGREASRGDQIENAAYFVKKGYAEDLQESDLTLDSLEEKLSHLLSHKEDYQAKMKAS
                     KELKSLADFYQLLKKDLS"
     gene            5700..6899
                     /gene="divIB"
                     /locus_tag="VYO11_001668"
     CDS             5700..6899
                     /gene="divIB"
                     /locus_tag="VYO11_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIB"
                     /protein_id="HEV1596198.1"
                     /translation="MSKDKKNEDKEILEELKELSEWQKRNQEYLKKKAEEEAALAEEK
                     EKERQARMGEESEKSEDKQDQESETDQEDSESAKEESEEKVASSEADKEKEEKEESES
                     KEKEEQDKKLAKKATKEKPAKAKIPGIHILRAFTILFLSLLLLIVSAYLLSPYATMKD
                     IRVEGTVQTTADDIRQASGIQDSDYTINLLLDKAKYEKQIKSNYWVESAQLVYQFPTK
                     FTIKVKEYDIVAYYISGENHYPILSSGQLETSSVSLNSLPETYLSVLFNDSEQIKVFV
                     SELAQISPELKAAIQKVELAPSKVTSDLIRLTMNDSDEVLVPLSEMSKKLPYYSKIKP
                     QLSEPSVVDMEAGIYSYTVADKLIMEAEEKAKQEAKEAEKKQEEEQKKQEEESNRNQT
                     TQRSSRR"
     gene            7132..7833
                     /gene="pyrF"
                     /locus_tag="VYO11_001669"
     CDS             7132..7833
                     /gene="pyrF"
                     /locus_tag="VYO11_001669"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HEV1596199.1"
                     /translation="MREHRPIIALDFPSFEAVKEFLALFPAEESLYLKVGMELYYAAG
                     PEIVSYLKGLGHSVFLDLKLHDIPNTVKSAMKVLSQLGVDMTNVHAAGGVEMMKAARE
                     GLGSQAKLIAVTQLTSTSEAQMQEFQNIQTSLQESVIHYAKKTAEAGLDGVVCSAQEV
                     QVIKQATNPDFICLTPGIRPAGVAVGDQKRVMTPADAYQIGSDYIVVGRPITQAEDPV
                     ATYHAIKDEWTQDWN"
     gene            7867..8499
                     /locus_tag="VYO11_001670"
     CDS             7867..8499
                     /locus_tag="VYO11_001670"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HEV1596200.1"
                     /translation="MTLAKDIASHLLKIQAVYLKPEEPFTWASGIKSPIYTDNRVTLA
                     YPETRTLIENGFVEAIKEAFPEVEVIAGTATAGIPHGAIIADKMDLPFAYIRSKPKDH
                     GAGNQIEGRVAQGQKMVVVEDLISTGGSVLEAVAAAKREGADVLGVVAIFSYQLPKAD
                     KNFADAGVKLVTLSNYSELIHLAQEEGYITPEGLDLLKRFKEDQENWQEG"
     gene            8679..9082
                     /locus_tag="VYO11_001671"
                     /pseudo
     CDS             8679..9082
                     /locus_tag="VYO11_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000829085.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            9178..9942
                     /locus_tag="VYO11_001672"
     CDS             9178..9942
                     /locus_tag="VYO11_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1596201.1"
                     /translation="MEFFICNLVRVVQSPRFYMSLFLTLLCMSLGNFLAFNGIYKIEG
                     LSIFFAASSIRGFSPISLVAALICTLPYSSQIIEDAESHFLTAQLCRISKKKYLAIVG
                     STVIISSFLVFFLPYLLLLGINLLVTPYQEIYIGDYSGALKELFDSNQLLYSLVTTLW
                     YGVWGAVFSIFGLASALLVKKKLGAIFIPVAYMMVGGILWAILGLSYLEPVTTLALGY
                     QKDISLSLVSAHLAFILFVSCLVVYGTFFLHSEDYV"
     gene            9942..10694
                     /locus_tag="VYO11_001673"
     CDS             9942..10694
                     /locus_tag="VYO11_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1596202.1"
                     /translation="MKQFVQFYKKDFLAVLVYFILLLSCVLSSTVYLLRCRQYSIHPN
                     VLEWILVLLQDMTTGVYCFPFTYILFFFYLMNNYFNRLECRIRLKSIKHFTSFSFKLA
                     ALSTGIWTATLFLLIFLIAFSNGFSFSLEIKEVDFLREFYGISIANNASFFIGFFFSY
                     IAYYFFLSLLTISSFSWFKKSNMSLVFLFTFLFVESLFWIYQLNNGIIGLLPIFQYMV
                     NSNPYALIYWLTLLSIIIPLTVFSVHRNWRRV"
     gene            10704..11402
                     /locus_tag="VYO11_001674"
     CDS             10704..11402
                     /locus_tag="VYO11_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1596203.1"
                     /translation="MGKLSSHMWRLNQIIYTKYFWGYVLFWILICLGLWYWLEGNDRL
                     VIEILKGPNLSQNSFLVLSIWLLHWFIIHTFFLAVVYRRRASDFFMEVIRFSSIKLWI
                     RYQIWTCFLYGLILIMVKVLVIQFMLQLPNWDIGVLFIVDSLNACVLSLLCFMLYALG
                     ANVQMNFACVSFFLLMIVFGGLFVGNRTNYLFYILNRGNGDIGRDLFLQLLFLVFLFK
                     SIFYFTRQKRRFIE"
     gene            11399..12046
                     /locus_tag="VYO11_001675"
     CDS             11399..12046
                     /locus_tag="VYO11_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1596204.1"
                     /translation="MNEIITLKNIELKLKKTCVFQNLNFSCKQGEIIGITGANGSGKS
                     VLFKLIAGLYSPSYGEVLINGENIVPERKIPANLGALIEEPGFINYYSGFKNLQYLAS
                     IRGVVGNQEINDTLKIVGLYEQKDQKVKTYSLGMRKKLGIAQAIMENPSILLLDEPMN
                     ALDKSSVENMRTLFRKLSSEKGTTILIASHSEEDIRILCDKVYAIEDKVCTLCSD"
     gene            complement(12133..12999)
                     /locus_tag="VYO11_001676"
     CDS             complement(12133..12999)
                     /locus_tag="VYO11_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV1596205.1"
                     /translation="MKLFKPLLTVLALAFALIFITACSSGGNAGSSSGKTTAKARTID
                     EIKKSGELRIAVFGDKKPFGYVDNDGSYQGYDIELGNQLAQDLGVKVKYISVDAANRA
                     EYLISNKVDITLANFTVTDERKKQVDFALPYMKVSLGVVSPKTGLITDVKQLEGKTLI
                     VTKGTTAETYFEKNHPEIKLQKYDQYSDSYQALLDGRGDAFSTDNTEVLAWALENKGF
                     EVGITSLGDPDTIAAAVQKGNQELLDFINKDIEKLGKENFFHKAYEKTLHPTYGDAAK
                     ADDLVVEGGKVD"
     gene            complement(13011..13769)
                     /locus_tag="VYO11_001677"
     CDS             complement(13011..13769)
                     /locus_tag="VYO11_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV1596206.1"
                     /translation="MSETILEIKELKKSFGDNPILQGLSLEIKKGEVVVILGASGCGK
                     STLLRCLNGLESIQGGDIFLDGQSIVENKKDFHLVRQKIGMVFQSYELFPHLDVLQNL
                     ILGPIKTQGRDKKEVTEEALQLLDRVGLLDKQHSFARQLSGGQKQRVAIVRTLLMNPE
                     IILFDEVTASLDPEMVREVLELINDLAQEGRTMILVTHEMQFAQAIADRIIFLDQGKI
                     AEEGTAQAFFTNPQTKRAQEFLNVFDFSQFGSYL"
     gene            complement(13770..14447)
                     /locus_tag="VYO11_001678"
     CDS             complement(13770..14447)
                     /locus_tag="VYO11_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001154125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV1596207.1"
                     /translation="MQDSEIQVLFQGNNLLRILQGLGVTIGISILSVLLSMMFGTVMG
                     IIMTSHSRIIRFLTRLYLEFIRIMPQLVLLFIVYFGLARNFNINISGETSAIIVFTLW
                     GTAEMGDLVRGAITSLPKHQFESGQALGLTNVQLYYHIIIPQVLRRLLPQAINLVTRM
                     IKTTSLVVLIGVVEVTKVGQQIIDSNRLTIPTASFWIYGTILVLYFAVCYPISKLSTH
                     LEKHWRN"
     gene            complement(14407..15087)
                     /locus_tag="VYO11_001679"
     CDS             complement(14407..15087)
                     /locus_tag="VYO11_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000384089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV1596208.1"
                     /translation="MDWSIVEQYLPLYQKAFFLTLHIAVWGILGSFLLGLIVSIIRHY
                     RIPVLAQVATAYIELSRNTPLLIQLFFLYFGLPRIGIVLSSEVCATLGLVFLGGSYMA
                     ESFRSGLEAISQTQQEIGLAIGLTPLQVFRYVVLPQATAVALPSFSANVIFLIKETSV
                     FSAVALADLMYVAKDLIGLYYETDIALAMLVVAYLIMLLPISLVFSWIERRFRHAGFG
                     NPSTLSGK"
BASE COUNT         4564 a         2622 c         3251 g         4691 t
ORIGIN      
        1 aaattcgatt ttttccttga caacaaataa taaaaatgct attcttatta tataagaaat
       61 cggtttcaaa aaagagagag gaggatttat tttgttgcat tgttgctcag ggtgtgcttt
      121 ttttgaaagg aaaaataaaa tgaaaacgaa aaaacataga ttacttgctc tagctcttat
      181 ttcaagcttt acattattgg gagctgcatc agctgctgta caatatccag atggaggagt
      241 atggacatat ggagaaggtt caggaggtgg ttgggctttt tcaaattact atcatggtaa
      301 aaaatatcat tattcttctg ttgtaagtaa atgggatagt cattcagata aaggatcagc
      361 acctgcaggg aaaacttcag aggcttggat ttggactaaa tttggggaac aagtatcatt
      421 ttactatgac tatgactaat atttagtttt cttagataat tccccttgta agaaattaca
      481 gggggaattt tgtttacaag gagtctacta tgaagaaact attcatatta ctatcaactt
      541 tttttctcag cttcttcttt gcttggatta ttgtcttacg tgcgccacaa tatttatatg
      601 caagctatga ttccgttact ttacttcgtg tcaaaaaaga ggctcaggaa ccgactcgtg
      661 aggtatttga acaggaattg gagaagtttg taaactcaga acagagttta atagctagga
      721 gaattgtaga accgagtaag gatgggacga ctcactttac ttatgcaact tatggtcagg
      781 gaacattacc aaaacaattc caagaagcta gccaagaaag tcgtgaacgt agtgatccgc
      841 taaatagtta tctcctttta tcaggctcct tgacaaaaga aaagctagct gataaattag
      901 gagatttagg ttataaagca attgctgacc gaaagacacc tccctattct cttgcttttc
      961 gaatgttact aaatcccctt attttaatta gtttagcaat atttggctta tctttctttg
     1021 ctttagtgat tatcactcgg attaaggaaa tgagagcagc aggtataaaa ctcttttctg
     1081 gtcagactct cttatccatt atggggcatt ctttatctac tgatattaag tggctccttc
     1141 tatcagccct cctttccttc ctaggtgggg gagtcgttct ttttagtcaa ggtttgtttt
     1201 atcctatctt gttagccacc tatggttttg ggattagttt ctatctgttg tttttattgg
     1261 cgatttcaat tttactaatg ctcctttatc taatgagttt gagttacaaa gcattagttc
     1321 ccgttattaa gggaagatta ccccttaaac gcctgatgat tttaacccta ttgtgtcagt
     1381 tggttgctgt ctttacagtg ggatacgctg ttaagacagg tttgacgtct taccaacgat
     1441 tgaaagaact tgaaatttca aaacaagcat ggcatgacag agtagactat tatcaaattt
     1501 cttttggctt aggtgacaga gtaaatgata cagaaaatca gaataagtgg tatgaatttt
     1561 ccaaagaagc agttgaaaaa gaacaggctc tatttgtaaa agagaatctc attcattttg
     1621 caaatcctca aggaaaaaat gaaaacgggg aaacactgga tacctatagt ccagatgcta
     1681 atgttctcta tgtgagtcca agttatttag acaaggaaaa tgtggctgta aatgatgaga
     1741 ctagacagaa actagctcat cttcaaaaag gggaatttgg actcttatta ccagaatctc
     1801 ttcgttcaca ggaagcagaa cttaagaaag tttttgaaga acgtttgaac tattacggaa
     1861 aatcaagcga ggataaagac gctcctttag agtatgaaat gagagcgatt gttagctatc
     1921 ttccaacagg acaaaaacgc tttgtttata ataacggtga aagtccagta tctattcagt
     1981 acttaaccga tccgatttta gttgtattta ctccaacatc tacaggtgat agtttcattt
     2041 caaaatatgt ttggtctatc aatgctggaa aacaactctt tatcaaagga tatgagagtg
     2101 ggctagaact cttaaagaaa gctggaattt atgagcaagt atcctatctt aaagaaggaa
     2161 gaagtgttta tctaactcgt tataatgaag ttcaaactga aacagcaact ttaatcttag
     2221 gagctattgt tgggatagcc agttccttat tactctttta ttctgtcaat cttctatatt
     2281 tcgagcaatt ccgccgagat atcttgatta aacgaatttc aggtttacga ttttttgaaa
     2341 cacatgctca gtatatggtt agccaatttg ccagttttgt atttggtgct agtttcttta
     2401 ttttaagcag tcgagacttg gtgattggct tgctcacttt attggtcttt ctagctagtg
     2461 cagttttgac gctttaccgt caagcgcaga aagaatctcg tgtttctatg acaattatga
     2521 aaggaaaata ggatgattga actaaagaat atatctaaaa aatttggaag ccgtcagcta
     2581 ttttcagata cgaatcttca ttttgaaggt gggaaaattt atgccttaat cggtacaagt
     2641 ggctgtggta agacaacact cttgaatatg attggacgat tagagccata tgacaaagga
     2701 caaatcatct atgatggtac ttctcttaag gacatcaagc cttctgtttt ctttagagat
     2761 tacttgggat acttatttca agattttggc ttaattgaaa gccaaaccgt caaagagaat
     2821 ctcaatctgg gtttagttgg taaaaagttg aaggaaaaag agaaaatctc tttgatgaaa
     2881 caagctctaa accgtgtaaa cctctcttat ttggatttga agcaacctat atttgagtta
     2941 tcaggaggag aagcacaacg tgttgcatta gcgaagataa ttttaaagga tccacctttg
     3001 atcctcgcag atgaaccaac cgcttcctta gaccccaaaa actctgagga attactttcc
     3061 atcctagaat ctttaaaaaa tccgaatcgg accattatta ttgcgaccca caatcctctg
     3121 atttgggagc aagtggatca ggtcattcga gttaccgatt tatcacatag atgatatggt
     3181 aagattcagt tagaagaaag agtcacaaac acactttgtg gcttttttat ttccataaaa
     3241 atggtaaaat agtaggagta gaaatggagt tcgagacatg aaagtaatag atcaatttaa
     3301 aaataagaaa gtccttgttt taggtttggc caagtctggt gaatctgcgg ctcgtttgtt
     3361 ggacaagtta ggtgccattg tgacagtaaa tgatgggaag cctttcgagg acaatccagc
     3421 tgcccaatgt ttgctggaag aagggatcaa ggtcattaca ggtggccatc ctttggaact
     3481 cttggatgaa gagttcgccc tcatggtaaa aaatccaggt atcccctaca gcaatcccat
     3541 gattgaaaag gctttggcca agggaattcc agtcttgact gaggtggaat tggcttattt
     3601 gatttcagaa gcaccgatta ttggtatcac aggatcgaac ggtaagacaa ccacaacgac
     3661 tatgattggg gaagttttga ctgctgctgg gcaacatggt cttttatcag ggaatatcgg
     3721 ctatcctgcc agtcaggttg ctcaaatagc atcagataag gacacgcttg ttatggaact
     3781 ttcttctttc caactcatgg gtgttcaaga attccagcca gagattgcgg ttattaccaa
     3841 cctcatgcca actcatatcg actaccatgg gtcattttct gaatatgtag cagccaagtg
     3901 gaatatccag aacaagatga cagcagctga tttccttgtc ttgaacttta atcaagactt
     3961 ggcaaaagac ttgacttcca agacagaagc cactgttgta ccattttcaa cacttgaaaa
     4021 ggttgatgga gcttatctgg aagatggtca actctacttc cgtggtgaag tagtcatggc
     4081 agcgaatgaa atcggtgttc caggtagcca caatgtggaa aatgcccttg cgactattgc
     4141 tgtagccaag cttcgtggtg tggacaatca aaccatcaag gaaactcttt cagccttcgg
     4201 tggtgtcaaa caccgtctcc agtttgtgga tgacatcaag ggtgttaaat tctataacga
     4261 cagtaaatca actaatatct tggctactca aaaagccttg tcaggatttg ataacagcaa
     4321 ggtcgtcttg attgcaggtg gtttggaccg tggcaatgag tttgacgaat tggtgccaga
     4381 cattactgga ctcaagaaga tggtcatcct gggtcaatct gcagaacgtg tcaaacgggc
     4441 agcagacaag gctggtgtcg cttatgtgga ggcgacagat attgcagatg cgacccgcaa
     4501 ggcctatgag cttgcgactc aaggagatgt ggttcttctt agtcctgcca atgccagctg
     4561 ggatatgtat gctaactttg aagtacgtgg cgacctcttt atcgacacag tagcggagtt
     4621 aaaagaataa tatgaaaaaa attgtcttta caggtggggg gacggttgga cacgttaccc
     4681 tcaatctttt gttaatgccc aagttcatcg aagatggttg ggaagtccac tatatcgggg
     4741 acaagcgtgg tatcgaacac caagaaatcc ttaagtcagg tttggatgtc accttccatt
     4801 ctattgcgac tggaaaattg cgtcgctatt tctcttggca aaatatgctg gacgtcttca
     4861 aagtttgctg gggaatcgtc caatcgctct ttatcatgtt gcgacttcgt ccacagaccc
     4921 ttttttcaaa ggggggcttt gtctcagtac cgcctgttat cgctgcgcgt gtgtcaggag
     4981 tgcctgtctt tattcacgaa tctgacctgt ctatgggctt ggccaataaa atcgcctata
     5041 aatttgcgac taagatgtat tcaacctttg agcaagcttc gagtttgtct aaggttgagc
     5101 atgtgggagc agtgaccaag gtttcagatc aaaaaaatcc agaaccagat gaattggtgg
     5161 atattcaaag ccattttaat cataaattgc cgactgtatt gtttgttggc ggttctgcag
     5221 gtgctcgtgt ctttaaccaa ttggtgacag accataagaa agaactaaca gagcgctaca
     5281 atattatcaa tctaactgga gattctagcc tgaatgagtt gaggcaaaat ctttttcgtg
     5341 ttgactatgt gaccgatctc tatcaaccct tgatggaatt ggctgatatt gttgtgacac
     5401 gaggtggtgc caatacgatt tttgagctct tggcgatagc aaaattgcat gtcattgtgc
     5461 cgcttggtcg tgaagctagt cgtggtgacc agattgaaaa tgcagcttac tttgtaaaaa
     5521 aaggctatgc agaagacctt caagaaagcg atttgacctt ggatagtttg gaagagaagc
     5581 tttctcactt actaagtcac aaggaagatt accaagctaa gatgaaagct tctaaggaat
     5641 tgaaatctct agcagatttt tatcaattgt tgaaaaaaga tttatcataa ggaaagtaaa
     5701 tgtcaaaaga taagaaaaat gaggacaaag aaatcctcga agaattgaaa gagttatcag
     5761 aatggcagaa acgaaaccaa gaatatctaa aaaagaaggc tgaagaagaa gcggctctag
     5821 ctgaggagaa ggaaaaggaa agacaagctc ggatgggaga agaatctgag aagtcagagg
     5881 acaaacagga ccaggagagt gaaacagacc aggaagattc agaatcagct aaggaagagt
     5941 ctgaagaaaa agtagcatcc tcagaggctg acaaagagaa agaagagaaa gaagaatcag
     6001 agtctaaaga gaaggaggaa caggataaaa agcttgctaa aaaggctaca aaggaaaaac
     6061 cagccaaagc aaagattcct ggtatccata tcttgcgagc cttcacgatt ttatttctaa
     6121 gtctgctttt attgattgtc tctgcctact tgctcagtcc ttatgcgacc atgaaagata
     6181 ttcgtgttga gggaacggtg caaactacag ctgatgatat tcgacaggct tcaggcattc
     6241 aggattcgga ttatacgatt aaccttctgc tagacaaggc aaaatatgaa aagcagatta
     6301 agtctaacta ttgggttgaa tcagctcaac ttgtctatca atttccaact aagttcacta
     6361 ttaaggtcaa ggaatatgat attgtggcct actatatttc tggtgaaaat cattatccta
     6421 ttctttccag tggtcagctt gagactagtt ctgtgagtct gaacagttta ccagaaactt
     6481 atttatcagt tctctttaat gatagtgaac aaatcaaggt ttttgtctca gaacttgctc
     6541 aaattagccc agaactcaag gcggctatcc aaaaggtgga attagcccca agcaaggtga
     6601 catccgattt aattcgattg accatgaatg attcggacga agtcttggtt cctctatctg
     6661 aaatgagtaa gaaactgcca tattacagta agattaagcc acaattgtca gaaccgagtg
     6721 tggtcgacat ggaagctgga atctacagct acactgtggc ggataaatta attatggagg
     6781 ctgaggaaaa agccaaacaa gaggccaagg aagccgagaa aaaacaagaa gaagaacaga
     6841 aaaaacaaga ggaagagagc aatcgaaacc aaacgaccca gcgctcatcg cgtcgctagg
     6901 tttacttttt ctcttatagt tatttagtga ccatgttttt acttgacaag tgctagtaga
     6961 aataatagaa taatagaaaa cctttaaagc agtccagaga ggcagctaag gttagacggt
     7021 gaaagggtgg agactaccca tttttcgtgg aaccttgctg ttggcaggtt ccttttttcg
     7081 tggcttctgt tggtcagact ctctcactag taaaggtaaa aggagaaacc tatgcgagaa
     7141 catcgtccaa tcattgctct tgattttcct agttttgagg cggtcaagga atttttagct
     7201 cttttcccag cagaagaaag cctttatctc aaggtaggga tggagcttta ttacgcagcg
     7261 gggcctgaga ttgtgtccta cttaaaaggt ttgggtcata gtgtcttttt ggatctcaaa
     7321 cttcatgaca ttcctaatac agtcaagtca gccatgaagg tcttgtctca gcttggtgtc
     7381 gatatgacta atgtccatgc ggctggtggt gtagagatga tgaaggcggc gcgtgaaggt
     7441 cttgggagtc aagccaaatt gatcgctgta actcagctca catcaacgtc agaagctcag
     7501 atgcaggagt ttcaaaatat ccaaaccagt ctgcaagagt ctgtgattca ctatgccaag
     7561 aagacagctg aagctggctt ggatggtgtt gtttgctcgg ctcaggaagt acaagtcatc
     7621 aagcaggcta ccaatccaga ttttatctgt ctgacaccag ggattcgtcc agctggtgtt
     7681 gcagttggag atcaaaaacg agtcatgaca cctgctgatg cctatcaaat cggcagtgac
     7741 tatatcgtag tgggacgtcc cattacccaa gctgaggatc ctgttgcaac ttatcatgcc
     7801 atcaaggatg aatggacaca ggactggaat taaagaacta gattagaaaa ataaaaggag
     7861 aataccatga cacttgctaa agatatcgct agccacctct tgaaaatcca agccgtttac
     7921 ctcaaaccag aggaaccctt cacttgggca tctggtatca agtcaccgat ttacactgat
     7981 aatcgtgtga cactagccta tccagaaact cgtaccctaa ttgaaaatgg ttttgtggaa
     8041 gctatcaaag aagcctttcc tgaagtagaa gtgattgcag gaactgcaac agcagggatt
     8101 ccacacggag ccattattgc tgataaaatg gacttgcctt ttgcctacat ccgtagcaaa
     8161 ccaaaagacc acggagctgg taatcaaatc gaaggtcgcg tagctcaagg tcaaaaaatg
     8221 gtagtggttg aagaccttat ttcaacgggt ggttcagttc ttgaagctgt agcagcagcc
     8281 aagcgagaag gagcagatgt acttggagtt gtagcgattt tcagctacca attgccaaaa
     8341 gcagataaga actttgcaga tgctggtgtt aaacttgtga cgctttcaaa ctatagcgag
     8401 cttatccatc tagcccaaga agaaggttac atcacgccag agggccttga tcttctaaaa
     8461 cgctttaaag aagaccaaga aaattggcaa gaaggttagg tcagtaagat aaagagagac
     8521 gaggctaccg agcctctttt accattttat ttaaaatatg ataatatttt aaataaaatg
     8581 attgacaacg ctttctttta ttgatataat gaaaatataa tatgtatcaa attgatcaat
     8641 caactatctt gtttatcact tcttaggagg acgatgtcat gaaaagaaga aaaatatatt
     8701 ccttttttgc gtagttacaa ttgcatctag tttgtttctc cctacagttt tagctagaca
     8761 gattggaaat tatgatttaa cgttgccgcg ttggggttcg gatacaacta gtgagcttga
     8821 gaaagaaaac gcctctgctg gaattaataa tagtgacagc actggtggcg gtaaaaggtt
     8881 aaatacctct attcgtagcg cctatagtgg gtcagatatt accccggtat attcattggg
     8941 gtctggctct aggattgtca tgtactataa tggaggtggt gacaattata ttggttctgg
     9001 tactagatta gctatggcgc cacaatttgg aaatcatgta agaattcata cttcaggttc
     9061 ttggagtcca gattcttatt aacttacttg tcagagtaag ccttaaagat ggttgattgt
     9121 gggtgtagca tgaaaaaaga atgctacacc ctatttttat tataaggagg agtaaggatg
     9181 gaatttttca tttgtaatct tgtacgagtc gttcaatcac ctcgatttta tatgtcttta
     9241 tttttgaccc ttctttgcat gagtttagga aatttccttg ctttcaatgg tatttataaa
     9301 attgaaggtt tatcgatttt ttttgccgct tcttctattc gaggattttc accgattagc
     9361 ctagtagctg cacttatctg tacactgccc tattctagtc agataataga ggatgctgag
     9421 agtcattttc taacagcaca attgtgtcga atttctaaaa agaagtatct ggctattgtg
     9481 ggtagtactg taattatttc ttcttttcta gtcttttttc tcccctattt attattatta
     9541 ggaattaatc ttttagtgac tccttatcag gaaatttata ttggagatta tagtggtgcc
     9601 ttaaaagaat tatttgattc caatcagttg ctctatagtc ttgtgacgac tctctggtat
     9661 ggagtttggg gcgctgtgtt ctctattttt ggactagcta gtgctttgct agtgaagaaa
     9721 aaattaggag ctattttcat cccagttgcc tatatgatgg ttggtggtat tttatgggct
     9781 attttagggc tatcttactt agaacctgtg acaacgctag ctttgggata tcagaaagat
     9841 atcagtcttt ccttagttag tgctcatctt gcttttattt tatttgttag ttgtttggtt
     9901 gtttatggta cattttttct acattcagag gactatgtat aatgaaacaa tttgttcaat
     9961 tttataaaaa agatttctta gcagtattgg tttattttat attactgcta tcctgtgttt
    10021 tatctagtac agtatattta ttgcgctgtc gccaatattc aatccatcca aatgtattag
    10081 aatggatctt agttttactt caagatatga cgactggagt atattgcttt ccgttcacat
    10141 atatattgtt ctttttttat ttgatgaata actattttaa taggttggag tgtcgcattc
    10201 gtctgaaatc aattaagcac tttaccagtt ttagtttcaa attagcagct cttagtacgg
    10261 ggatttggac ggcgacttta tttttattga tttttctaat tgcatttagt aatggtttta
    10321 gcttctcttt ggagataaag gaggttgatt ttttaagaga attttatggt ataagtattg
    10381 caaacaatgc tagtttcttt ataggatttt ttttctctta tatagcatac tatttctttt
    10441 tatccttact tactattagc agtttttctt ggtttaaaaa atcaaacatg agcttagtat
    10501 ttctgtttac ttttttattt gtagaatcct tattctggat ttatcagttg aacaatggga
    10561 taattggatt attgccaatt tttcagtata tggtaaattc caatccgtat gcattgattt
    10621 attggcttac attactatct atcataattc cattgactgt attttctgtt catagaaact
    10681 ggaggagagt gtaaaagttg gaaatgggaa agttaagtag tcacatgtgg aggttgaatc
    10741 agataatcta taccaagtac ttttggggtt atgttctttt ttggatattg atttgtttag
    10801 gattatggta ttggttagaa ggaaatgata gacttgttat agaaatttta aaagggccta
    10861 atctgagtca aaactctttt ttagtcttat ctatatggtt gcttcattgg tttattattc
    10921 atacattttt tctagcagtt gtatatcgta gaagagcatc cgatttcttt atggaagtga
    10981 ttcgattttc ttctattaag ctctggatta ggtatcagat ttggacctgt tttctttatg
    11041 gacttatttt aatcatggta aaagttctag tgattcaatt tatgttacag ttaccaaact
    11101 gggatatagg agttttgttt atagttgatt ctttgaatgc ttgtgtgcta tccttgcttt
    11161 gctttatgtt atacgcacta ggagcgaatg tacaaatgaa ctttgcttgc gttagtttct
    11221 ttttactcat gattgtgttt ggtggtctat ttgtaggaaa tcgaactaat tatctatttt
    11281 atattttgaa tcgagggaat ggagatatag gacgagattt atttcttcag ttgctatttt
    11341 tagtctttct ttttaaaagc attttctatt tcactcgtca aaagaggagg tttatagaat
    11401 gaatgaaata attacattaa aaaatattga gttgaaatta aaaaaaacat gtgtttttca
    11461 aaaccttaat tttagttgta aacaggggga aattatagga attactggtg cgaatggctc
    11521 agggaaaagt gtattgttta aattaatagc tggtttatat agtccgtctt atggagaagt
    11581 gttaatcaat ggggaaaata ttgttcctga gagaaaaatt ccagctaatt tgggagcttt
    11641 gattgaagaa cctggtttta taaattatta tagtggcttt aagaatttac aatatttggc
    11701 aagcatacga ggagtagttg gtaatcagga aatcaatgat acactgaaaa tagttggtct
    11761 atatgagcaa aaagaccaga aagttaaaac ttattcgcta ggtatgagga aaaagctagg
    11821 gattgctcaa gcaattatgg agaatccctc tattctttta ctagatgaac ctatgaatgc
    11881 cttggataaa tcaagtgtag aaaatatgag aacattgttt agaaaactct ctagtgaaaa
    11941 agggacaaca attttgattg ctagtcatag tgaagaggat attcgtatct tatgtgataa
    12001 agtatatgca atagaagata aagtatgtac actgtgttca gattgaacat cttagataga
    12061 ctcaggatgt tataggtaaa atcttaaaaa gggattggag cttaaaatcc agttcctttt
    12121 aagagttaat gactaatcaa cttttccacc ttcaacaacc aggtcatctg ctttagcagc
    12181 gtcaccatag gttgggtgaa gtgttttttc ataggccttg tggaagaagt tttccttgcc
    12241 taatttttca atatctttat tgatgaagtc tagcaattct tggttgcctt tttgaactgc
    12301 tgccgcaatg gtatcgggat caccgaggga agtaattcct acttcaaatc ctttattttc
    12361 aagcgcccaa gctagaactt ccgtattgtc agttgaaaag gcatctccac gtccgtcaag
    12421 aagagcttgg taagagtcac tgtattggtc gtatttttgg agtttgattt ctggatgatt
    12481 cttttcaaaa taagtctcag cagtcgttcc ttttgtgaca attaaggttt taccttcaag
    12541 ttgtttgacg tctgtaatga gaccagtctt aggtgatacg acacccagag aaactttcat
    12601 atatggaagg gcaaaatcaa cttgtttctt acgttcgtca gttactgtaa agttagcaag
    12661 agtaatatct accttgtttg aaatcaagta ttccgcacgg ttggcagcat cgactgaaat
    12721 gtatttaacc ttgacaccaa ggtcttgagc tagttggttc cctagttcaa tatcgtagcc
    12781 ttggtaagaa ccatcattgt caacgtagcc aaacggtttt ttatctccaa acacggcgat
    12841 tcgcagttca ccgctttttt tgatttcatc gatagtgcga gctttggcag ttgtttttcc
    12901 agaggatgaa ccagcgtttc cacctgagct acaagcagtg ataaagataa gggcaaaggc
    12961 aagtgctaaa acagttaaga gtggtttgaa tagtttcata agaatctcct ttatagatat
    13021 gagccgaatt ggctaaagtc aaagacgttt aaaaattcct gggctcgttt ggtttgcgga
    13081 ttggtaaaga aggcttgagc tgttccttct tcagcgattt tcccttggtc gaggaagata
    13141 atccggtcag caatggcttg ggcaaactgc atttcgtggg ttactaaaat catggtacgg
    13201 ccttcttggg ccaaatcatt gataagttcc agcacctcac gcaccatttc tggatccagc
    13261 gaagcagtca cctcgtcaaa aaggatgatt tctggattca ttaggagggt acggacaatt
    13321 gcaacacgtt gcttctgtcc accagataat tgacgggcaa agctatgttg tttatccagc
    13381 aaaccgacac gatctagtaa ttgcaaagct tcttccgtta cttctttctt gtcccttcct
    13441 tgagttttga tagggcctag gatgaggttt tgtaagacat ccagatgggg aaagagttca
    13501 taactttgaa agaccatgcc aatcttttgg cgaactaggt gaaaatcttt tttattttca
    13561 acgatagact gaccatccag aaaaatatct ccaccttgaa tactttctaa gccgttgagg
    13621 caacgaagga gggtactttt cccacaacca gatgccccta ggatgacaac aacttcccct
    13681 tttttaattt ctagagaaag tccttggagg atgggattgt ctccgaagga tttttttagt
    13741 tccttgattt ctaagatagt ttcagacatt tagtttctcc aatgtttttc taagtgagtg
    13801 gatagtttgg aaatagggta gcaaactgcg aaatataaga ctagaatggt tccataaatc
    13861 caaaatgaag cagttgggat ggtcaggcga ttgctatcga tgatttgttg tccaactttg
    13921 gtcacttcca caaccccaat caaaacaact aatgaagtgg ttttaatcat ccgagtgaca
    13981 agattgatag cctgcggtag cagtcttctc aagacttgtg ggatgatgat gtggtagtaa
    14041 agttgaacat tagtcaagcc gagtgcttgt ccactttcaa actgatgttt agggagagaa
    14101 gtgatagctc cacgtaccaa gtctcccatt tcagctgttc cccagagggt aaaaacgata
    14161 atagctgaag tctcacctga gatattgata ttaaagtttc gagccaagcc aaagtaaacg
    14221 atgaagagta gcaccagctg gggcatgata cggataaatt ccagatacaa tcgtgttaaa
    14281 aatcgtatga ttctagaatg ggaggtcatg atgattccca tgactgttcc gaacatcatg
    14341 gataagagga cagacaggat ggatatccca atcgtaacgc ccaatccctg taagattctc
    14401 aggagattat ttccctgaaa gagtacttgg atttccgaat cctgcatggc ggaacctcct
    14461 ttctatccag ctaaagacca gtgagatggg tagcagcatg atcagataag caactaccaa
    14521 catagctagc gcaatgtctg tctcatagta gagaccaatc aaatccttgg cgacgtacat
    14581 gaggtcggcc aaagccactg ctgagaaaac agaggtttcc ttgataagga aaatgacatt
    14641 ggcactaaag gaggggagtg ccaccgctgt tgcttgcgga agaaccacat agcgaaagac
    14701 ctgtagaggt gtcagaccaa tagcgaggcc aatctcctgc tgggtttgac tgatggcttc
    14761 cagcccactt cggaaagatt ctgccatata ggatcctcct aaaaagacaa gcccaagcgt
    14821 tgcacagact tctgaagata ggacaatccc gattcgggga agaccgaagt agagaaagaa
    14881 gagttgaatc aaaaggggcg tattacgtga caattcaatg taggctgtcg ctacttgcgc
    14941 caaaacaggg attcgataat gtcggatgat actaacgatt aaaccgagca gaaaggatcc
    15001 caaaattccc caaactgcaa tatgcaaggt cagaaagaat gccttttgat atagtggtag
    15061 atattgttca acaatggacc aatccaaaaa tagaacctcc catctagaaa taatacagtt
    15121 attgtagc
//
LOCUS       DAVLXH010000049        14258 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00028199
            SAMN33607166-rid17955573.denovo.049, whole genome shotgun sequence.
ACCESSION   DAVLXH010000049 DAVLXH010000000
VERSION     DAVLXH010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607166
            Sequence Read Archive: SRR23725544
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14258)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14258)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721421.1
            Genome Coverage       :: 115x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:42:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,210
            CDSs (total)                      :: 2,161
            Genes (coding)                    :: 2,023
            CDSs (with protein)               :: 2,023
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 73 of 138
            Pseudo Genes (incomplete)         :: 60 of 138
            Pseudo Genes (internal stop)      :: 40 of 138
            Pseudo Genes (multiple problems)  :: 31 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14258
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607166-rid17955573.denovo.049"
                     /strain="AUSMDU00028199"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1349"
     gene            83..880
                     /locus_tag="VYO11_001680"
     CDS             83..880
                     /locus_tag="VYO11_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HEV1596209.1"
                     /translation="MVSSEFISKIEFACNKKESLYSQSKFKYAIRSMFAGAFLTFSTA
                     AGAVGADLINKIAPGSGRFLFPFVFAWGLAYIVFLNAELVTSNMMFLTAGSFLKKISW
                     RKTAEILLYCTLFNLIGALIAGWGFAHSAAYANLTHDSFISGVVEMKLGRSNELVLLE
                     AILANIFVNIAILSFILVKDGGAKLWLVLSAIYMFVFLTNEHIAANFASFAIVKFSVA
                     ADSIANFGVGNMLRHWGVTFIGNFIGGGLLMGLPYAFLNKNEDTYVD"
     gene            1028..1150
                     /locus_tag="VYO11_001681"
     CDS             1028..1150
                     /locus_tag="VYO11_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetylhomoserine sulfhydrylase"
                     /protein_id="HEV1596210.1"
                     /translation="MTRDFKFETLQLHAGQVVAPATKSRAVPIYQTTFFVFDDT"
     gene            1172..2212
                     /locus_tag="VYO11_001682"
     CDS             1172..2212
                     /locus_tag="VYO11_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001231001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetylhomoserine
                     aminocarboxypropyltransferase/cysteine synthase"
                     /protein_id="HEV1596211.1"
                     /translation="MRKPGNIYTRITNPTTAALEGGVEALATASGMTAVTYTILALAH
                     AGEHVVAASTIYGGTFNLLKEPLPRYGITTTFVDVDNLEEVEAAIKDNTKLVLIETLG
                     NPLINIPDLEKLAEIAHKHQIPLVSDNTFATPYLINVFSHGVDIAIHSATKFIGGHGT
                     TIGGIIVDSGRFDWTASGKFPQFVDEGPSCHNLSYTRDVGAAAFIIAVRVQLLRDTGA
                     ALSPFNAFLLLQRLETSSLRVERHVQNAETIVDFLVNHPKVEKVNYPKLADSPYHALA
                     EKYLPKGVGSIFTFHVKGGEEEARKVIDNLEIFSDLANAADAKSLVVHPATTTHGQLS
                     EKDLEAAGVTPN"
     gene            2383..3657
                     /locus_tag="VYO11_001683"
     CDS             2383..3657
                     /locus_tag="VYO11_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2130 domain-containing protein"
                     /protein_id="HEV1596212.1"
                     /translation="MNEIKCPNCGEVFTVNESQYAELLSQVRTAEFDKELHDRMKQEL
                     ALAEQKAMNEQQTKLAQKDQEIAQLQSQIQNFDTEKELAKKEVEQTSHQALLAKDKEV
                     QALENQLATLRLEHENQLQKTLSDLEKERNQVKNQLLLQEKENELSLASVKQNYEAQL
                     KAASEQVEFYKNFKAQQSTKAIGESLEQYAESEFNKVRSFAFPNAYFEKDNKVSSRGS
                     KGDFIFRECDENGVEIISIMFEMKNEADGTEKKHKNADFYKELDKDRREKNCEYAVLV
                     TMLEADNDYFNTGIVDVSHEYEKMYVVRPQFFIQLIGLLRNAALNSLKYKQELALVRE
                     QNIDITHFEEDLDAFKLAFAKNYNSASTNFGKAIDEIDKAIKRMEEVKKFLTTSENQL
                     RLAHNKLEDVSVKKLTRKNPTMKAKFEALKGE"
     gene            3667..4545
                     /gene="truB"
                     /locus_tag="VYO11_001684"
     CDS             3667..4545
                     /gene="truB"
                     /locus_tag="VYO11_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HEV1596213.1"
                     /translation="MNGIINLKKEAGMTSHDAVFKLRKILGTKKIGHGGTLDPDVVGV
                     LPIAVGKATRMVEFMQDEGKIYEGEITLGYSTTTEDASGEVIAETPVLSPLDEKLVDE
                     AIASLTGLITQIPPMYSAVKVNGRKLYEYARAGQEVERPERQVTIYQFERTSPISYDG
                     QLARFTFRVKCSKGTYIRTLSVDLGEKLGYAAHMSHLTRTSAAGLQLEDALALEEIAE
                     KVEAGQLDFLHPLEIGTGDLVKVFLTPEEATEVRFGRFIELDQTDKELAAFEDDKLLA
                     ILEKRGNLYKPRKVFS"
     gene            4786..5088
                     /locus_tag="VYO11_001685"
     CDS             4786..5088
                     /locus_tag="VYO11_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000985087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEV1596214.1"
                     /translation="MMRNEFRERVEQLLQQKEINENSELSHLFRLAIQNLDRNEKYQS
                     VMANLSQGLSLYLMTHHYQAPKSVIDFGLWIAKAPSQERGRLAFLQMLAQTLQGFR"
     gene            5196..5834
                     /gene="udk"
                     /locus_tag="VYO11_001686"
     CDS             5196..5834
                     /gene="udk"
                     /locus_tag="VYO11_001686"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HEV1596215.1"
                     /translation="MQNRPIIIGVTGGSGGGKTSVSRAILSHFPDEKISMIEHDSYYK
                     DQSHLTFEERVKTNYDHPFAFDTDLMIEQIKELLAGRPVDIPTYDYTEHTRSSKTYRQ
                     EPQDVFIVEGILVLEDKRLRDLMDIKIFVDTDDDVRIIRRIKRDMEERGRSLDSVINQ
                     YLGVVKPMYHQFIESTKRYADIVIPEGVSNTVAIDLLTTKIAKILEEARNSK"
     gene            5962..7302
                     /locus_tag="VYO11_001687"
     CDS             5962..7302
                     /locus_tag="VYO11_001687"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HEV1596216.1"
                     /translation="MEKYLSVTTLTKYLKMKFDKDPYLERVYLTGQVSNFRKRPTHQY
                     FSLKDDHAVIQATIWSGIYQKLGFDLEEGMKINVIGRVQVYEPSGSYSIIIEKAEPDG
                     VGALAIQFEQLKKKLTEEGLFQERFKQALPQFSKRIGVVTSRSGAVIRDIITTVSRRF
                     PGVDILLYPTKVQGEGAAEEIARNIARANQRDDLDLLIIGRGGGSIEDLWAFNEEIVV
                     RAIFESRLPVISSVGHETDVTLADFVADRRAATPTAAAELATPVTKLDVLAHLQNQEK
                     RIATAVRNVLSKKQETLKKCSQSVIFRQPERLYDGYLQRLDQLQLRLKQSLRTRISDN
                     KQLVQARTHQLVQLSPVTKIQRYQDRLGQLDKLLGSQMALVYDAKVAEAKRLSEALLM
                     LDTSRIVARGYAIVKKEESIVDSVESLKKKDQVTLLMRDGQVELEVKDVKTKEI"
     gene            7280..7492
                     /locus_tag="VYO11_001688"
     CDS             7280..7492
                     /locus_tag="VYO11_001688"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HEV1596217.1"
                     /translation="MSKQKKFEENLAELETIVQSLENGEIALEDAITAFQKGMVLSKE
                     LQATLDKAEKTLVKVMQEDGTESDFE"
     gene            7489..8364
                     /locus_tag="VYO11_001689"
     CDS             7489..8364
                     /locus_tag="VYO11_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HEV1596218.1"
                     /translation="MKKQEKLALVESALEDFYGDQQFASSLRESVLYSIHAGGKRIRP
                     FLLLEVLEALQVAIKPAHAQVATALEMIHTGSLIHDDLPAMDDDDYRRGRLTNHKKFG
                     EAMAILAGDALFLDPYALIAQADLPSQIKVDLIANLSLASGSLGMVAGQVLDMEGEHQ
                     HLSLEELQTIHANKTGKLLAYPFQAAAIIAELSPEMQVKLKTVGELIGLAFQVRDDVL
                     DVTASFEEIGKTPQKDLQAEKSTYPALLGLEESIAFCNQTLDQANEKLEEIAQQLPFE
                     TESIVSVVESLRING"
     gene            8357..9172
                     /locus_tag="VYO11_001690"
     CDS             8357..9172
                     /locus_tag="VYO11_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HEV1596219.1"
                     /translation="MAKERVDVLAYKQGLFETREQAKRGVMAGLVVAVLNGERFDKPG
                     EKIPDDTELKLKGEKLKYVSRGGLKLEKALQVFDLSVDGATTIDIGASTGGFTDVMLQ
                     NSAKLVFAVDVGTNQLAWKLRQDPRVVSMEQFNFRYAEKTDFEQEPSFASIDVSFISL
                     SLILPALHRVLADQGQVVALVKPQFEAGREQIGKNGIIRDAKVHQNVLESVTAMAVEV
                     GFSVLGLDFSPIQGGHGNIEFLAYLKKEKSASNQILAEIKEAVERAHSQFKNE"
     gene            9165..9596
                     /locus_tag="VYO11_001691"
     CDS             9165..9596
                     /locus_tag="VYO11_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001034407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEV1596220.1"
                     /translation="MNKKERLEKIRRLVTDYQIGTQEEIVEHLKEAGITATQATVSRD
                     IKELGIVKIPLRDNTYVYELPKSIVKSLQLAEDNIESAELMDKMINLQVIPGNTAFVK
                     AQLIDTFADKIFSCLTDDSSILVIARSGSLAEEIFEQVKNW"
     gene            9603..11270
                     /gene="recN"
                     /locus_tag="VYO11_001692"
     CDS             9603..11270
                     /gene="recN"
                     /locus_tag="VYO11_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HEV1596221.1"
                     /translation="MLLEISIKNFAIIEAISLNFEKGMTVLTGETGAGKSIIIDAMNM
                     MLGARATTDVIRHGAPKAEIEGLFSVENSRLLQEIFDEQGLELGDEIIIRREILQNGR
                     SISRVNGQMVNLSVLRAIGQHLVDIHGQHDHEELMRPQLHIQMLDEFGDAAFWDLKET
                     YQTSFDAYRKMRKQVLEVKKNQQEHKARIEMLEFQMAEIEAANLQAGEDLALNQERDK
                     LLNHKNIADTLTNAYSMLDNEDFSSLANVRSAMNDMESVEEYDSEYREISSSLSETYY
                     VLEDISKRLEAIIEDLDFDGNRLMQVENRLDLLHTITRKYGGTVDDVLLYFAKITEEY
                     NLLTGNNLSSEDMEAELKKLEVNLVNLAGQLASARHNLAQQLEAEIKQELQDLYMEKA
                     QFQVRFSKGKFSREGNKMVEFYISTNPGEDFKPLVKVASGGELSRLMLAIKSAFSRKE
                     GKTSIVFDEVDTGVSGRVAQAIAQKIHKIGQHGQVLAISHLPQVIAIADYQFFIEKIS
                     NDHSTVSTVRLLTVEERVEEVAKMLAGDDVTEAALTQARELLRNREK"
     gene            11272..12000
                     /locus_tag="VYO11_001693"
     CDS             11272..12000
                     /locus_tag="VYO11_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000133310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein phosphatase"
                     /protein_id="HEV1596222.1"
                     /translation="MTDYYVIGDVHGKAGMLEDLLKTWDGQTQLLFLGDLIDRGEDSH
                     RVLEMVKDLVDNQGAICLSGNHEYMFLTWLDDPEESYDHYRRNGGDTTINSILGRPLD
                     APVDGVEDAKRVAAEAADLVEFIRQMPFVVETDKYIFVHAGIDLTLDDWHETTDYKKV
                     WLRKPFHGAENHTGKTIVFGHTPVYGLLQQERGTSELWTTEDGKIGMDGGAVYGGVLH
                     GIVFTDQGMTEHHFIENDGFVAED"
     gene            12079..13902
                     /gene="lepA"
                     /locus_tag="VYO11_001694"
     CDS             12079..13902
                     /gene="lepA"
                     /locus_tag="VYO11_001694"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001047203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HEV1596223.1"
                     /translation="MNLEELKKRQEKIRNFSIIAHIDHGKSTLADRILEKTETVSSRE
                     MQAQLLDSMELERERGITIKLNAIELNYTAKDGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAILVVDAAQGIEAQTLANVYLALDNDLEIMPIINKIDLPAADPERVRTEIEDVI
                     GLDASEAVLASAKAGIGIEEILEQIVEKVPAPTGDVTAPLKALIFDSVYDAYRGVILQ
                     VRVMDGVVKPGDKIQLMSNSKTFDVAEVGIFTPKAVGRDFLATGDVGYIAASIKTVQD
                     TRVGDTVTLATNPAAEPLHGYKQMNPMVFAGLYPIESNKYNDLREALEKLQLNDASLQ
                     FEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVIYKVNLTDGESMD
                     VSNPSEFPDPTKIATIEEPYVKAQIMVPQEFVGAVMELAQRKRGDFVTMDYIDDNRVN
                     VIYQIPLAEIVFDFFDKLKSSTRGYASFDYELSEYRPSKLVKMDILLNGDKVDALSFI
                     VHKDFAYERGKLIVDKLKKIIPRQQFEVPIQAAIGHKIVARTDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKAGKKRMKSIGSVEVPQEAFLSVLSMDEE"
     gene            complement(14061..14141)
                     /locus_tag="VYO11_001695"
                     /pseudo
     CDS             complement(14061..14141)
                     /locus_tag="VYO11_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
BASE COUNT         4229 a         2599 c         3388 g         4042 t
ORIGIN      
        1 acttttatga aatacagaaa acgcttccta aaacctaaag tttgtgatat aattatcaag
       61 aaaaaagatt taggagttta ttatggtttc ttcagaattt atctcaaaga ttgaatttgc
      121 ttgcaataag aaagaaagtc tttatagtca aagcaaattt aagtatgcga ttcgttcgat
      181 gttcgcaggt gcatttttaa ccttcagtac tgctgcaggt gcagttgggg ctgacttgat
      241 taataaaatt gcaccaggta gtggacgctt cctctttcca ttcgtttttg cttggggctt
      301 ggcctacatt gtttttttga atgccgagtt ggtcacttca aacatgatgt tcttgactgc
      361 tggtagtttc ttaaaaaaaa tctcttggag aaaaacagct gagattttac tatactgtac
      421 cttgttcaac cttatcggag ccttgatagc agggtggggc tttgctcatt cggcagccta
      481 tgcgaatctg acacacgata gtttcatctc aggtgttgtt gagatgaagt taggccgctc
      541 aaatgaattg gtcttgcttg aggcgatttt ggcaaatatt tttgtaaata ttgcgattct
      601 gtcatttatt ttggtcaaag atggtggtgc caaactttgg cttgtgttgt cagctattta
      661 catgtttgta ttcttaacaa acgagcacat tgcggcgaac tttgcttctt tcgcgattgt
      721 gaaattcagt gttgctgcgg attcaattgc caacttcggt gttggaaata tgcttcgcca
      781 ctggggtgtg actttcatcg gaaactttat cggaggaggc ctcttgatgg gtcttccata
      841 tgccttcctc aataaaaacg aagatactta tgtagattaa gaaaatgagc acgattgagt
      901 cgtgcttttt tcattttcaa aataaggtaa tagctatttc ttatatcaaa atatagaaaa
      961 ctgatatttg taaactataa ctcaaggtgc tacaatatcc ttaataaaat aatatggagg
     1021 tcaccttatg actcgtgatt ttaaatttga aactctacaa ctacatgctg gtcaagttgt
     1081 ggctccagct actaagtctc gtgcagtgcc gatttatcaa acaacatttt ttgtttttga
     1141 tgacacgtag gaaggtgccg atctgtttgc cttgaggaaa ccagggaaca tttatactcg
     1201 tatcaccaat cctacaacag ctgcccttga aggtggtgtt gaagcgctag caacagcatc
     1261 aggtatgact gcagtgactt atacgatttt ggcgcttgcc catgctggtg agcatgtagt
     1321 ggctgcttcg actatttacg gtggaacctt caatcttttg aaagaacccc ttcctcgtta
     1381 tggtatcaca acaacctttg tcgatgttga taatttggag gaagtagaag cagctatcaa
     1441 agacaatacc aagcttgtct tgattgaaac cttgggtaac cccttgatta atattccaga
     1501 cctggaaaaa ctggcagaga ttgctcataa acatcaaatc ccacttgtgt cagacaatac
     1561 ttttgcaaca ccttatttga ttaacgtctt ctctcatggc gttgacattg ccattcactc
     1621 tgcgactaag tttatcggtg ggcatggtac aactattgga ggaataattg tcgatagtgg
     1681 tcgttttgac tggacggctt cagggaaatt ccctcaattt gttgacgagg gtccaagctg
     1741 ccacaatttg agctatactc gtgatgtggg tgcagcagcc tttattatag ctgttcgagt
     1801 tcaattgctt cgtgatacag gtgcagcctt gtcaccattc aatgctttcc tcttgctaca
     1861 aagacttgaa acctcttcac ttcgtgtgga acgccatgta caaaatgctg agacaattgt
     1921 tgattttctt gtcaaccatc ctaaggtaga aaaggtaaat tatccaaaac ttgcagatag
     1981 tccttatcat gccttggctg agaaatactt gccaaaaggt gtcggttcaa tctttacctt
     2041 ccacgtcaaa ggtggcgagg aagaagcacg caaggtcatt gataatttag aaatcttttc
     2101 tgaccttgca aacgcggcag atgctaaatc gcttgttgtc catccagcaa caaccactca
     2161 cggtcaattg tcagaaaaag acctagaagc agcaggtgtc acaccaaact aaattcgttt
     2221 gtcaatcggt cttgaaaatg tagaagattt gattgaagac ttgcgcttgg ccttggaaaa
     2281 aatttaaagt aaaagaagat aaacagtggg cttcgactca ctgtttttga ttttccctca
     2341 ggcatgatat aatggttaaa gaagtctaga aagaggaacg atatgaacga aatcaaatgt
     2401 cccaactgtg gggaagtctt tacagtaaat gagagtcagt atgccgaact cttgtcccaa
     2461 gtgagaacgg cagagtttga taaggaacta cacgatagga tgaagcagga actggccttg
     2521 gctgagcaaa aggccatgaa tgagcaacag actaaactgg ctcagaagga tcaagaaatt
     2581 gcgcaattgc agagtcaaat ccaaaacttt gatacagaaa aagaattggc caagaaagaa
     2641 gttgaacaga caagccatca ggccttattg gctaaggaca aggaagtaca ggccttggaa
     2701 aaccagttgg cgaccttgcg tttggagcat gaaaatcaac tgcaaaagac cctttctgac
     2761 ctagaaaaag aacgcaatca ggtcaaaaat cagctcctac tgcaagaaaa ggaaaatgag
     2821 ttgtctttgg cttctgttaa gcaaaactac gaagcccagc tcaaagcagc cagtgaacaa
     2881 gtcgagtttt ataagaattt taaggctcaa caatctacaa aagcgattgg ggaaagccta
     2941 gaacagtatg cagagagtga gtttaacaag gtccgtagtt tcgcctttcc aaatgcttac
     3001 tttgagaagg ataacaaggt ctcttcgcgt gggtctaaag gggactttat cttccgtgag
     3061 tgtgatgaaa atggagttga aatcatttct atcatgtttg agatgaaaaa cgaagcggac
     3121 ggaacagaga agaagcacaa gaatgcagat ttttacaagg aattggacaa ggaccgtcgg
     3181 gagaagaact gtgagtatgc cgttttggtg accatgcttg aggccgataa tgactacttt
     3241 aacacaggga ttgttgacgt cagccacgag tatgaaaaaa tgtatgttgt tcgtcctcaa
     3301 ttctttatcc agttgattgg tctcttacgt aatgcggcgc taaattccct aaaatacaag
     3361 caggagttgg ccttggttcg cgagcaaaat attgacatta cgcattttga ggaagatttg
     3421 gatgccttta agctagcttt tgctaagaac tataattcag cttcgactaa ctttggaaaa
     3481 gctattgatg aaatcgacaa ggccatcaaa cgcatggaag aggttaagaa attcctgact
     3541 acatctgaaa accaactccg tctagctcac aacaaattgg aagatgtctc tgttaaaaaa
     3601 ttgacccgga aaaatccaac aatgaaagcg aagttcgaag cactgaaggg ggagtagaaa
     3661 gcaaaaatga acggtattat caacttaaaa aaagaagcag gaatgacctc gcatgatgcg
     3721 gtttttaaac tgcgtaagat tttgggaacc aagaaaattg gtcatggtgg aaccttggat
     3781 ccggatgtgg tgggtgtttt gccgattgcg gttggcaagg cgacacgcat ggtcgagttt
     3841 atgcaggacg agggtaagat ctatgagggg gaaatcactc tgggctattc cacgacgact
     3901 gaggatgcta gtggggaagt gatcgcagaa acccctgttt tgtctccctt ggatgaaaag
     3961 cttgttgatg aagcgattgc tagcttgact gggcttatta ctcagattcc ccctatgtat
     4021 tcggcagtta aggttaatgg tcgcaagctc tatgagtatg cgcgtgctgg tcaggaagtg
     4081 gagcgtccag aacgtcaggt gaccatttat caatttgagc gaacaagtcc gatttcttat
     4141 gatggccaac ttgctcgatt cacttttcgt gtaaaatgca gtaaagggac ttacatccgt
     4201 actttgtcag ttgatttggg tgaaaagctt ggttatgcgg ctcatatgtc ccatttgact
     4261 cgtactagtg ctgctggctt acaattagaa gacgctcttg ccttggagga aattgctgaa
     4321 aaagtagagg ctgggcaatt agattttctc catcctttag agattgggac aggtgacctt
     4381 gtcaaagttt tcctaactcc agaagaggct acagaagttc gctttggtcg ttttattgag
     4441 ctagaccaaa cggacaaaga actggctgcc tttgaagatg ataaattgtt agccattcta
     4501 gaaaaacggg gcaatctcta taagccaagg aaggttttta gctagatcgt ttaggaataa
     4561 aaatcgggtg atagataaca attgcttgat aaaacctcat actaatagta gaatggtttt
     4621 gggaattata atattccaat tgttgcgagt tgtaggtact caaataatct atatagaaat
     4681 ttagaggtgt gaaatgaagc aatttaaaat tctttcagat aaatatttag agtccattac
     4741 aggttctggt gggaacttag gcccaggatt tggtgtgata attccatgat gcgaaatgag
     4801 tttcgagaaa gggtggagca acttcttcaa caaaaagaaa taaatgaaaa tagtgagttg
     4861 agtcacctgt ttcgtcttgc tatacaaaat ttagacagaa atgaaaaata ccaatcggtc
     4921 atggccaatt tgagtcaagg gttgtcactt tacctcatga cgcatcatta ccaggcacct
     4981 aagtctgtca ttgattttgg tttatggatt gccaaagctc ctagccagga aagagggaga
     5041 ttggctttct tgcagatgct tgctcaaacc ctacagggct ttcgttaaaa ctgtcgaaca
     5101 tcagagggaa gactctggtg ttttttgctg atgagactat aaattttgta aaaaatgtga
     5161 tagaatagac gacggataaa ataacggagg atagcatgca aaatagacca atcattattg
     5221 gagtgacagg tggttctggt ggtggtaaaa ccagtgtttc aagagccatt ttatcgcatt
     5281 ttcctgatga aaagatttcc atgattgagc atgattcata ctacaaggat cagtctcatt
     5341 tgacctttga agagcgtgtc aaaaccaact atgaccatcc ttttgccttt gatacagact
     5401 tgatgatcga gcagattaag gaattgttgg cagggcgtcc ggtggacatc ccgacctacg
     5461 actatacaga gcatacacgg agtagcaaga cctatcgtca ggagcctcaa gatgtcttta
     5521 tcgttgaggg cattttggtc ttggaggaca agcgtctgcg cgatttgatg gatatcaaga
     5581 tttttgtgga tacggatgac gatgtgcgta ttattcgtcg tatcaagcgt gatatggagg
     5641 agcgtggccg tagccttgat agcgttatta accagtactt aggtgtggtc aaaccaatgt
     5701 accaccagtt tatcgagtca actaagcgtt atgctgatat cgtcattcct gaaggggtta
     5761 gcaataccgt ggctatcgac ctgttgacga ccaagattgc aaagattttg gaagaagctc
     5821 gaaacagcaa ataatcacat gtggaggcct tgcctccttt ttctattttt ccctcataat
     5881 ggtacataaa tggagatttt taggcatatt tttggtataa taatacccat gaaagagcaa
     5941 gtaaatgaat agtaggtgga gatggaaaag tatttatcgg taacaacttt gaccaagtat
     6001 ctgaaaatga aattcgataa agacccatac ttggaacggg tctatttaac tggtcaagtt
     6061 tccaactttc gtaaacgacc tactcaccaa tatttctccc taaaggatga ccatgcagtt
     6121 attcaagcga ccatctggtc tgggatttat cagaaattag ggtttgacct ggaagaagga
     6181 atgaagatca atgtgattgg gcgtgtacag gtctatgaac caagtggtag ctactccatc
     6241 atcattgaaa aagctgagcc tgatggggtt ggggcgcttg cgattcagtt tgaacaactt
     6301 aagaaaaaat tgacagaaga aggcctgttt caagaacgct tcaagcaagc tctgccccaa
     6361 ttttctaaga gaattggtgt agtaaccagc cgtagtggag ccgttattcg agatattatc
     6421 acgaccgtca gcaggcgatt cccaggtgtt gacatccttc tttatccgac caaggttcaa
     6481 ggtgaagggg ctgcggagga aattgctaga aatattgcgc gtgctaatca acgggacgat
     6541 ttggatttgc tcattattgg tcgtggaggt ggttctattg aggatctctg ggcctttaac
     6601 gaagaaattg tggtacgagc tatttttgaa tctcgtttgc cagttatctc tagtgtgggg
     6661 catgagacgg atgtgacctt ggcagatttt gtggcagatc gacgcgctgc aacgccaaca
     6721 gcggcggctg aactggcaac acctgtgacc aagttggatg tattagctca tttgcaaaat
     6781 caggaaaaac ggatagcaac ggcagtccga aatgttctat ctaagaaaca agagactttg
     6841 aaaaaatgca gtcagtctgt tatctttaga caacctgagc gcttgtatga cggttatttg
     6901 caacgcttgg accaactgca actgcgtttg aaacaaagtt tgcgaactcg gatttctgat
     6961 aacaaacaat tagttcaagc aagaactcat caattagtac aattatcacc tgttaccaaa
     7021 atccaacgct atcaagaccg tttaggacag ttggacaagc tcttaggtag ccaaatggcg
     7081 ttagtttatg acgccaaggt tgctgaggcc aagcgacttt cggaagcttt gctcatgttg
     7141 gatactagcc gaatcgtggc gcgtggttat gctattgtca aaaaagaaga gtccattgta
     7201 gattcggttg agagtttgaa gaaaaaagac caagtaacgc ttttgatgcg agatggtcaa
     7261 gtagaattag aggttaaaga tgtcaaaaca aaagaaattt gaggaaaatc tagcagaact
     7321 ggaaaccatt gtccaaagtt tggaaaatgg tgaaattgct ctggaagatg cgattactgc
     7381 ctttcaaaag ggcatggtct tgtcaaaaga gctccaagct acgctggaca aggctgaaaa
     7441 gaccttggtc aaggtcatgc aagaagacgg aacagaaagt gattttgaat gaaaaagcaa
     7501 gaaaaattag ctcttgtcga gtcggctttg gaagattttt atggagacca gcagtttgcc
     7561 tctagtttac gggagtctgt tctctattct attcatgctg gtggcaagcg tattcggcct
     7621 tttctcttgt tagaagttct ggaagccttg caggttgcca tcaaacctgc tcacgcgcag
     7681 gtagctactg ccttggagat gattcataca gggagcttga ttcacgatga ccttcctgct
     7741 atggatgatg acgattatcg aagagggcgg ttaaccaatc acaagaaatt cggtgaagct
     7801 atggccattt tggctggaga tgccttattc ttagacccat atgccttgat tgcgcaggca
     7861 gatttgccaa gtcagatcaa ggtggacttg attgccaact tatcccttgc ttcaggtagt
     7921 ctgggtatgg tggcagggca agttttggat atggagggcg aacaccagca cttgtctctg
     7981 gaagaacttc agactattca tgccaataag actgggaagt tactagccta tcccttccaa
     8041 gcggcagcta ttatagctga attgtcacct gaaatgcagg tgaagctgaa aactgtgggt
     8101 gaattgattg gacttgcttt tcaagtcaga gatgatgtac tggatgtgac agctagtttt
     8161 gaggaaatcg gcaagacacc tcaaaaggat ttgcaggcag aaaaatcaac ctatcctgcc
     8221 ttgttgggct tggaagagtc cattgccttt tgtaaccaaa ccctggatca agctaatgaa
     8281 aaattagaag aaattgccca gcagcttccc tttgaaacag aatcgattgt aagtgtagta
     8341 gaaagtttga gaatcaatgg ctaaggaaag agtggatgta ctagcttata aacaggggtt
     8401 gtttgaaacg agagagcagg ccaagcgagg tgtgatggct ggcctagtcg tagcagtcct
     8461 taatggagaa cggtttgaca agccaggaga gaaaattcca gatgataccg aattaaaact
     8521 caagggggag aaactcaagt atgtcagccg tggtggtttg aaactggaaa aggccttgca
     8581 ggtctttgat ttgtcggtgg atggcgcgac tacgattgat atcggggcct ctactggagg
     8641 ttttaccgat gtcatgctac agaatagtgc caagttggtc tttgcagtcg atgttggtac
     8701 caatcagttg gcttggaaat tacgccaaga cccacgagtt gtcagcatgg agcagttcaa
     8761 tttccgctat gctgaaaaga ctgatttcga gcaggagccg agctttgcca gtattgatgt
     8821 gagtttcatt tcccttagtc tgattttgcc agccttgcac cgtgtcttgg ctgatcaagg
     8881 tcaggtggta gcacttgtca aacctcagtt tgaggcagga cgtgagcaga ttgggaaaaa
     8941 tggaattatt cgagatgcta aggttcatca gaatgtcctt gaatctgtaa cagctatggc
     9001 agtagaggta ggtttttcag tccttggctt ggacttttct cccatccaag gtggacatgg
     9061 aaatattgaa tttttagcgt atttgaaaaa agaaaagtca gcaagcaatc agattcttgc
     9121 tgagattaaa gaagcagtag agagggcgca tagtcaattt aaaaatgaat aaaaaagaga
     9181 gacttgaaaa aattagaaga ttggtgacag attatcaaat cggcacgcaa gaagaaattg
     9241 tagaacattt gaaagaagca ggtatcactg ccactcaggc gacggtatcc cgagatatca
     9301 aagagttagg tattgtcaaa attcctttga gagacaacac ctatgtctac gaattaccaa
     9361 aatcaatcgt aaaaagtctg caactggctg aagacaatat cgaatcggct gaattgatgg
     9421 ataagatgat caatctccaa gttattccag gaaatacggc ttttgtaaaa gctcagttaa
     9481 tcgatacttt tgcagacaag atttttagtt gtttgactga tgatagctcg attttagtca
     9541 ttgccagaag tggaagtcta gcagaggaaa tctttgaaca agtaaaaaat tggtaggtct
     9601 atatgttact tgaaatttcg ataaaaaact ttgccattat tgaggctatt tccctcaatt
     9661 ttgaaaaggg gatgactgtc ctgactggtg aaacgggtgc agggaagtcg attatcattg
     9721 atgccatgaa tatgatgttg ggagctcgtg cgacgacaga tgttattcgt catggtgcac
     9781 caaaggcaga gattgagggg cttttctcag ttgagaatag tcgtctttta caggaaattt
     9841 ttgatgagca aggtttagaa ttaggtgatg aaattatcat ccgtcgggaa atcttgcaaa
     9901 atggtcgtag tatcagccgt gtaaatggtc agatggttaa tctgtctgtt ttgcgagcta
     9961 ttgggcaaca tcttgtagat attcatggtc agcatgacca tgaggagtta atgcgtcccc
    10021 aactgcatat ccagatgttg gatgaatttg gtgatgccgc tttttgggac ttgaaagaaa
    10081 cctatcaaac gagttttgat gcctatcgga aaatgcgcaa gcaggttctg gaagtcaaga
    10141 aaaaccaaca ggaacacaag gcacgtatcg aaatgttgga atttcaaatg gcagagattg
    10201 aggcagcaaa cttgcaggct ggagaagact tggctctcaa tcaagagcga gataaactcc
    10261 tcaaccacaa aaatattgcg gatacactga ccaatgccta cagtatgttg gacaatgaag
    10321 atttttcaag tctggccaat gttcgttcag ccatgaatga catggaaagt gtcgaagagt
    10381 atgattctga ataccgtgaa atttcaagct ctctgtctga gacctactat gttttagaag
    10441 acattagcaa acgtttggaa gctatcattg aggaccttga ttttgatggc aatcgcctga
    10501 tgcaggttga gaatcgtttg gacctccttc atactattac tcgtaagtat ggtgggactg
    10561 ttgatgatgt tttgctttat tttgccaaga ttacggaaga atacaatctc ttgacaggca
    10621 ataatctttc gtctgaggac atggaagcag agcttaagaa gttggaagtc aatcttgtca
    10681 atttggcagg tcaacttgct tctgctcgtc ataatttggc tcagcaactc gaagctgaga
    10741 ttaaacaaga actgcaagat ctttatatgg aaaaagccca gtttcaggtt cgttttagta
    10801 agggaaaatt cagtcgtgag ggaaataaaa tggttgagtt ttatatttca accaaccctg
    10861 gagaagactt taaacccttg gttaaggttg cttctggagg ggaattatct cgtctcatgt
    10921 tagccattaa gtctgccttt tcacgtaaag aaggcaagac tagcattgtc tttgatgagg
    10981 tggatacggg agtttcaggt cgtgttgctc aagctattgc tcagaaaatt cataaaattg
    11041 gtcagcatgg tcaggttttg gctatctccc atttgccaca agtaattgcg attgcagatt
    11101 atcaattctt tattgagaag attagtaatg accattcaac ggtttcgact gttcgtctct
    11161 tgacggtcga agagcgagtg gaggaagttg ccaagatgtt ggcaggtgat gatgtgacag
    11221 aagcagccct gacgcaagcc agagaattgt tgagaaacag ggagaaataa gatgacagat
    11281 tattatgtaa ttggagatgt tcacggaaaa gctgggatgc tggaagacct tcttaaaacc
    11341 tgggatggtc agacccagtt gctctttcta ggtgatttga ttgacagagg tgaggatagt
    11401 caccgtgttc ttgaaatggt caaggacttg gtggacaatc aaggggctat ctgtttgtct
    11461 ggaaaccacg agtatatgtt tttgacttgg ctagatgacc cagaagaaag ttatgaccat
    11521 tatcgtcgca atggtggaga tacaaccatt aactctatcc taggtcgtcc cttggatgca
    11581 ccagttgatg gagtagaaga tgccaagcgg gttgccgctg aagcggcaga cttggtcgaa
    11641 ttcattcgtc aaatgccatt tgtagtagag acagacaagt atatctttgt tcacgcaggt
    11701 attgatttga ctttggacga ctggcatgaa acaacagatt ataaaaaagt atggcttaga
    11761 aaaccattcc acggagctga aaatcatact ggaaaaacca ttgtcttcgg tcatacaccg
    11821 gtctatggtt tgttacagca agaacgcggt acatctgagc tttggactac agaagatggc
    11881 aagattggaa tggatggagg agctgtttat ggtggtgtcc ttcacgggat tgtctttaca
    11941 gaccaaggaa tgacagaaca ccactttatc gaaaatgacg gctttgtcgc tgaagattag
    12001 tactcctagc agggtatggt cttgtcaaaa tatcaaaaac aatttataat aaatagatac
    12061 cctgaaagga agagaatcat gaacttagaa gaattgaaaa aacgacagga gaagatccgt
    12121 aacttctcta ttatcgccca tattgaccac ggaaaatcaa ctctagcaga ccgcattttg
    12181 gaaaaaacag agacggtttc aagtcgtgaa atgcaggccc agcttttgga tagcatggag
    12241 ctagagcggg aacgtggaat tactattaag ttgaatgcca tcgagttgaa ttacactgca
    12301 aaagatgggg aaacttatat tttccacttg attgacacac cagggcacgt tgactttacc
    12361 tatgaagttt cacgttcgct agctgcctgt gagggtgcta ttttggtggt cgatgcggct
    12421 caaggaattg aggctcaaac tcttgccaac gtttatctgg ctttggataa tgatttggaa
    12481 atcatgccta tcattaataa aattgacctg ccggctgcag atccggagcg cgtgcgtaca
    12541 gagattgaag atgtgattgg tttggatgcc agtgaagcag ttttggcttc tgccaaggct
    12601 ggtattggga ttgaagaaat cctcgagcaa attgtagaaa aagtaccagc accaacgggt
    12661 gatgtgacgg cgccacttaa ggccttgatt ttcgactctg tttacgatgc ttaccgtggg
    12721 gttatcctcc aagtacgtgt catggacgga gtggtcaaac ctggtgataa gattcagctc
    12781 atgagcaata gtaagacctt tgatgtggcc gaagtcggta tttttacacc aaaagcggtt
    12841 ggtcgtgatt tccttgcgac tggtgatgtt ggttacattg cggcgtctat caagacggtt
    12901 caggatactc gtgtgggtga taccgttacc ttggcaacca atcctgcggc agaaccatta
    12961 catggttata agcagatgaa tcctatggtc tttgcgggtc tctacccaat cgaatcaaac
    13021 aagtacaatg acctgcgtga agcgcttgaa aaattgcaac tgaatgatgc tagtcttcag
    13081 tttgaaccag aaacatctca ggcacttgga tttggtttcc gttgtggatt tcttggactt
    13141 ctccatatgg atgttattca ggaacgttta gagcgtgagt tcaatattga cctcatcatg
    13201 acagctccgt ctgttattta caaagttaat ttgaccgacg gtgagtctat ggatgtgtct
    13261 aacccatctg agtttccaga cccaactaag attgcgacca ttgaagagcc ttatgtcaag
    13321 gcgcaaatca tggtaccaca ggagttcgtc ggagcagtaa tggagctagc tcagcgtaag
    13381 cgtggggact ttgtgactat ggactatatt gatgataacc gtgtcaatgt tatctatcaa
    13441 attcctcttg ctgaaattgt ctttgacttc tttgataaac ttaagtcttc gacacgtggt
    13501 tatgcaagct ttgactacga attgtcagaa tatcgcccat ctaagctggt gaaaatggat
    13561 atccttctca atggagataa ggtggatgcc ctcagcttta tcgttcacaa ggactttgcc
    13621 tacgaacgtg ggaaactcat cgttgataaa ctcaagaaaa tcatccctcg ccaacaattt
    13681 gaagttccaa tccaagcggc tattggacac aagattgtcg ctcgtactga tatcaaggcc
    13741 cttcgtaaga acgtacttgc taaatgttat ggtggtgacg tttctcgtaa gcgtaaactc
    13801 cttgaaaaac aaaaagctgg taagaaacgc atgaaatcca tcggatcagt tgaagttccg
    13861 caagaagcct tcctcagcgt cttgagtatg gatgaagaat aagttatcag aaatgccttt
    13921 ccttgttcac aggaaattta tataaaaatc aatagtaaag caggcttaga tggtctgctt
    13981 ttttagtttt tatactcttc gaaaatctct tcaaaccacg tcagcgtcgc cttaccgtat
    14041 gtatggttac tgacttcgtc agtttcatct acaacctcaa aactgtgttt tgagtaacct
    14101 gctgctagct tcctagtttg ctctttgatt ttcattgagt attagaacag aaaaatgctt
    14161 ggagtatttg tttgtgtgtt tatttttata taacaaacta taaacaaaac aaaaatataa
    14221 aaaaagagac aaaaaagaat agaaagtaat taacaacg
//
LOCUS       DAVLXH010000050        14134 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00028199
            SAMN33607166-rid17955573.denovo.050, whole genome shotgun sequence.
ACCESSION   DAVLXH010000050 DAVLXH010000000
VERSION     DAVLXH010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607166
            Sequence Read Archive: SRR23725544
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14134)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14134)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721421.1
            Genome Coverage       :: 115x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:42:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,210
            CDSs (total)                      :: 2,161
            Genes (coding)                    :: 2,023
            CDSs (with protein)               :: 2,023
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 73 of 138
            Pseudo Genes (incomplete)         :: 60 of 138
            Pseudo Genes (internal stop)      :: 40 of 138
            Pseudo Genes (multiple problems)  :: 31 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14134
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607166-rid17955573.denovo.050"
                     /strain="AUSMDU00028199"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1349"
     gene            95..325
                     /locus_tag="VYO11_001696"
     CDS             95..325
                     /locus_tag="VYO11_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000037109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HEV1596224.1"
                     /translation="MSKKDKKIEIQVADAKVNVGKDSFEGYTLTIGKKVIGEIAELDG
                     QFAIIKNGNVDSFYKKLEKAVEILIENYNLAK"
     gene            375..455
                     /locus_tag="VYO11_001697"
     tRNA            375..455
                     /locus_tag="VYO11_001697"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:409..411,aa:Tyr,seq:gta)
     gene            465..536
                     /locus_tag="VYO11_001698"
     tRNA            465..536
                     /locus_tag="VYO11_001698"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:497..499,aa:Gln,seq:ttg)
     gene            698..1900
                     /gene="rpsA"
                     /locus_tag="VYO11_001699"
     CDS             698..1900
                     /gene="rpsA"
                     /locus_tag="VYO11_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HEV1596225.1"
                     /translation="MNEFEDLLNSVSQVETGDVVSAEVLTVDATQANVAISGTGVEGV
                     LTLRELTNDRDADINDFVKVGEVLDVLVLRQVVGKDTDTVTYLVSKKRLEARKAWDKL
                     VGREEEVVTVKGTRAVKGGLSVEFEGVRGFIPASMLDTRFVRNAERFVGQEFDTKIKE
                     VNAKENRFILSRREVVEAATAAARAEVFGKLAVGDVVTGKVARITSFGAFIDLGGVDG
                     LVHLTELSHERNVSPKSVVTVGEEIEVKILDLNEEEGRVSLSLKATVPGPWDGVEQKL
                     AKGDVVEGTVKRLTDFGAFVEVLPGIDGLVHVSQISHKRIENPKEALKVGQEVQVKVL
                     EVNADAERVSLSIKALEERPAQEEGQKEEKRAARPRRPRRQEKRDFELPETQTGFSMA
                     DLFGDIEL"
     gene            complement(1985..3311)
                     /locus_tag="VYO11_001700"
                     /pseudo
     CDS             complement(1985..3311)
                     /locus_tag="VYO11_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            3505..4002
                     /locus_tag="VYO11_001701"
     CDS             3505..4002
                     /locus_tag="VYO11_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HEV1596226.1"
                     /translation="MLKSEKQSRYQMLNEELSFLLEGETNVLANLSNASALIKSRFPN
                     TVFAGFYLFDGKELVLGPFQGGVSCIRIALGKGVCGEAAHFQETVIVGDVTTYLNYIS
                     CDSLAKSEIVVPMMKNGQLLGVLDLDSSEIEDYDAMDRDYLEQFVAILLEKTAWDFTM
                     FEEKS"
     gene            4002..5657
                     /gene="dnaX"
                     /locus_tag="VYO11_001702"
     CDS             4002..5657
                     /gene="dnaX"
                     /locus_tag="VYO11_001702"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HEV1596227.1"
                     /translation="MYQALYRKYRSQNFSQLVGQEVVAKTLKQAVEQEKISHAYLFSG
                     PRGTGKTSVAKIFAKAMNCPNQVGGEPCNNCYICQAVTDGSLEDVIEMDAASNNGVDE
                     IREIRDKSTYAPSLARYKVYIIDEVHMLSTGAFNALLKTLEEPTQNVVFILATTELHK
                     IPATILSRVQRFEFKSIKTQDIKEHIHYILEKENISSEPEAVEIIARRAEGGMRDALS
                     ILDQALSLTQGNELTTAISEEITGTISLSALDDYVAALSQQDVPKALSCLNLLFDNGK
                     SMTRFVTDLLHYLRDLLIVQTGGENTHHSSVFVENLALPQKNLFEMIRLATVNLADIK
                     SSLQPKIYAEMMTVCLAEIKPEPALSGAVENEIATLRQEVARLKQELSNAGAVPKQVA
                     PAPSRPATGKTVYRVDRNKVQSILQEAVENPDLARQNLIRLQNAWGEVIESLGGPDKA
                     LLVGSQPVAANEHHAILAFESNFNAGQTMKRDNLNTMFGNILSQAAGFSPEILAISME
                     EWKEVRAAFSAKAKSSQTEKEVEESLIPEGFEFLADKVKVEED"
     gene            5685..5879
                     /locus_tag="VYO11_001703"
     CDS             5685..5879
                     /locus_tag="VYO11_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3272 domain-containing protein"
                     /protein_id="HEV1596228.1"
                     /translation="MNKQQFIIMALFTAAETYFFNEAWMTGRYIMAAFWAILLFRNFR
                     VSYVMGKIVDVIDQHFNRKD"
     gene            6029..6799
                     /gene="sufC"
                     /locus_tag="VYO11_001704"
     CDS             6029..6799
                     /gene="sufC"
                     /locus_tag="VYO11_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000114488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HEV1596229.1"
                     /translation="MSVIEIKDLHVEIEGKEILKGVNLTLKTGEIAAIMGPNGTGKST
                     LSAAIMGNPNYEVTKGEVLFDGVNILELEVDERARMGLFLAMQYPSEIPGITNAEFLR
                     AAMNAGKEDDEKISVREFITKLDEKMELLNMKEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFALLDEIDSGLDIDALKVVSKGVNAMRGEGFGAMIITHYQRLLNYITPDVVHV
                     MMEGRVVLSGGPELAARLEREGYAKLAEELGYDYKEEL"
     gene            6827..8089
                     /gene="sufD"
                     /locus_tag="VYO11_001705"
     CDS             6827..8089
                     /gene="sufD"
                     /locus_tag="VYO11_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HEV1596230.1"
                     /translation="MTRENIKLFSEMHAEPSWLADLRQKAFDKIETLELPVIERVKFH
                     RWNLGDGTITENEPSANVPDFTALDHHLKLVQVGTQTVFEQTPVELAEQGVVFTDFHS
                     ALEEIPELIEEFFMSSVKYDDDKLAAYHTAYFNSGAVLYIPDNVEITEPIEGIFYQDS
                     DSNVPFNKHIMIIAGKNSKISYLERLESRGEGSDKVTANITVEVIARSGAQVKFAAID
                     RLGENVTAYISRRGKLGNDASIDWAIGVMNEGNVVADFDSDLIGNGSHADLKVVALSS
                     GRQVQGIDTRVTNYGCNSIGNILQHGVILEKATLTFNGIGHIIKGAKGADAQQESRVL
                     MLSDQARSDANPILLIDENDVTAGHAASIGQVDPEDMYYLMSRGLDKATAERLVVRGF
                     LGSVIVEIPVKEVRDEMIATIEEKLSKR"
     gene            8100..9326
                     /locus_tag="VYO11_001706"
     CDS             8100..9326
                     /locus_tag="VYO11_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000887707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEV1596231.1"
                     /translation="MLDVEAIRKDFPILDQIVNDEPLVYLDNAATTQKPLVVLKAINS
                     YYEQDNANVHRGVHTLAERATASYEAARETIRKFINAGSTKEVLFTRGTTTSLNWVAR
                     FAEEILAEGDRVLISVMEHHSNIIPWQEACRKTGAELVYVYLKDGALDMEDLRAKLTD
                     KVKFVSLAHASNVLGVVNPIKEITQLAHQVGAIMVVDGAQSTPHMKIDVQDLDLDFFA
                     FSGHKMAGPTGIGVLYGKEKYLEQMSPVEFGGEMIDFVYEQFASWKELPWKFEAGTPN
                     MAGAIGLATAVDYLEKIGMDAVEAHEQELIAYVYPKLQAIEGLTIYGSQDLAQRSGVI
                     AFNLGDLHPHDLATALDYEGVAVRAGHHCAQPLLQYLEVPATARASFYIYNTKADCDK
                     LVDALQKTKEFFNGTF"
     gene            9313..9753
                     /locus_tag="VYO11_001707"
     CDS             9313..9753
                     /locus_tag="VYO11_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HEV1596232.1"
                     /translation="MALSKLDSLYMAVVADHSKNPHHQGKLEDAEQTSLNNPTCGDVI
                     NLSVKFDAEDRLEDIAFLNSGCTISTASASMMTDAVLGKTKQEILELATIFSEMVQGQ
                     KDERQGQLGDAAFLSGVAKFPQRIKCATLAWNALKKTIENQEKQ"
     gene            9807..11219
                     /gene="sufB"
                     /locus_tag="VYO11_001708"
     CDS             9807..11219
                     /gene="sufB"
                     /locus_tag="VYO11_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HEV1596233.1"
                     /translation="MAEERVEPKPIDLGEYKFGFHDDVEPVLSTGKGLNEGVIRELSA
                     AKGEPEWMLEFRLKSYETFKKMPMQTWGADLSEIDFDDLIYYQKPSDKPARSWDDVPE
                     KIKETFERIGIPEAERAYLAGASAQYESEVVYHNMKEEFQKLGIIFTDTDSALKEYPD
                     LFKQYFAKLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDIPLQTYFRINNENIGQFE
                     RTLIIVDEGASVHYVEGCTAPTYSSNSLHAAIVEIFALDGAYMRYTTIQNWSDNVYNL
                     VTKRAKAQKDATVEWIDGNLGAKTTMKYPSVYLDGEGARGTMLSIAFANAGQHQDTGA
                     KMIHNAPHTSSSIVSKSIAKGGGKVDYRGQVTFNKNSKKSVSHIECDTIIMDDLSASD
                     TIPFNEIHNSQVALEHEAKVSKISEEQLYYLMSRGLSESEATEMIVMGFVEPFTKELP
                     MEYAVELNRLISYEMEGSVG"
     gene            complement(11450..12691)
                     /locus_tag="VYO11_001709"
     CDS             complement(11450..12691)
                     /locus_tag="VYO11_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HEV1596234.1"
                     /translation="MKKIFLTLLTVSLLGGASTAVAQDFTIAAKHAIAVEANTGKILY
                     EKDATQPVEIASITKLITVYLVYEALENGSITLSTPVDISDYPYQLTTNSEASNIPME
                     ARNYTVEELLEATLVSSANSAAIALAEKIAGSEKDFVDMMRAKLLEWGIQDATVVNTT
                     GLNNETLGDNIYPGSKKDEENKLSAYDVAIVARNLIKKYPQVLEITKKPSSTFAGMTI
                     TSTNYMLEGMPAYRGGFDGLKTGTTDKAGESFVGTTVEKGMRVITVVLNADHQDNNPY
                     ARFTATSSLMDYISSTFTLRKIVQQGDAYQDSKAPVQDGKEDTVTAVAPEDIYLIEQI
                     GNQSSQSVQFTPDSKAIPAPLEAGTVVGHLTYEDKDLIGQGYITTERPSFEMVADKKI
                     EKAFFLKVWWNQFVRFVNEKL"
     gene            12794..13903
                     /locus_tag="VYO11_001710"
     CDS             12794..13903
                     /locus_tag="VYO11_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEV1596235.1"
                     /translation="MFRRNKLFFWTTEILLLTIIFYLWRQMGSLINPFVSVLNTIMIP
                     FLLGGFLYYLTNPIVTFLNKVCKLNRLLGILITLCTLVWGMVIGVVYLLPILINQLSS
                     LIISSQTIYSRVQDLIIDLSNYPALQNLDVEATIQQLNLSYVDILQNILNSVSNSVGS
                     VLSALISTVLILIMTPVFLVYFLLDGHKFLPMLERTILKRDRLHIAGLLKNLNATIAR
                     YISGVSIDAIIIGCLAYIGYSIIGLKYALVFAIFSGVANLIPYVGPSIGLIPMIIANI
                     FTDPHRLLIAVIYMLVVQQVDGNILYPRIVGSVMKVHPITILVLLLLSSNIYGVVGMI
                     VAVPTYSILKEISKFLSRLYENHKIMKERERELAK"
BASE COUNT         4239 a         2501 c         3093 g         4301 t
ORIGIN      
        1 ataaaactct atatcagaga agcctgatat agagtttttt cttgctagtt ttaggatttt
       61 cttgtaaaat agaaaaagtg aagagaggta tgaaatgagc aagaaagata aaaaaatcga
      121 aattcaagta gcggatgcca aagttaatgt tggtaaagac agttttgaag gttatacatt
      181 gactatcggt aaaaaagtta tcggagaaat tgccgaatta gacggacaat ttgccattat
      241 aaagaatggg aatgtcgata gtttttataa aaaattggaa aaagctgtgg aaattttgat
      301 tgaaaattat aatttagcaa aataagtctt gtttttttga aattttcatg atataatagt
      361 ccatgttgat tgtaggagag atagcgaaga ggctaaacgc ggcggactgt aaatccgctc
      421 cttcgggttc gggggttcga atccctctct ctccatttca ttaatggggt atagccaagc
      481 ggtaaggcaa gggactttga ctccctcatg cgttggttcg aatccagcta ccccagttct
      541 taggtaataa tcaagataga aagcaaaata tcttagggta ttttattttt ataattgaaa
      601 gacgtgaatg atatgaacat gtccttgcgg gtgcttagga aaaaaattat aagtatgtca
      661 agtttaagaa aaacttgatt gttggaggat tttttagatg aacgaatttg aagatttgct
      721 aaatagcgtt agtcaagttg agactggtga tgttgttagt gctgaagtat tgacagttga
      781 tgcgactcaa gctaacgttg caatctctgg aactggtgtt gaaggtgtct tgactcttcg
      841 cgaattgaca aacgatcgtg atgcagatat caatgacttt gttaaagtag gagaagtatt
      901 ggatgttctt gtacttcgtc aagtagttgg taaagatact gatacagtta cataccttgt
      961 atctaaaaaa cgccttgaag ctcgcaaagc atgggacaaa cttgttggtc gcgaagaaga
     1021 agttgttact gttaaaggaa cgcgtgccgt taaaggtgga ctttcagtag aatttgaagg
     1081 tgttcgtgga tttatcccag cttcaatgtt ggatactcgt ttcgtacgta acgctgagcg
     1141 ttttgtaggt caagaatttg atactaaaat caaagaagtt aacgctaaag aaaaccgctt
     1201 catcctttca cgtcgtgaag ttgttgaagc agctactgca gcagctcgcg ctgaagtatt
     1261 cggtaaattg gctgttggtg atgttgtaac tggtaaagtt gctcgtatca caagcttcgg
     1321 cgctttcatc gaccttggtg gtgttgacgg attggttcac ttgactgaat tgtcacatga
     1381 acgtaacgta tcaccaaaat cagttgtaac tgttggtgaa gaaattgaag tgaaaatcct
     1441 tgatcttaac gaagaagaag gacgtgtatc actttcactt aaagcaacag taccaggacc
     1501 atgggatggc gttgagcaaa aattggctaa aggtgatgta gtagaaggaa cagttaaacg
     1561 tttgactgac ttcggtgcat ttgttgaagt attgccaggt atcgatggac ttgttcacgt
     1621 atcacaaatt tcacacaaac ggattgaaaa tccaaaagaa gctcttaaag ttggtcaaga
     1681 agttcaagtt aaagttcttg aagttaacgc agatgcagaa cgcgtgtcac tttctattaa
     1741 agctcttgaa gaacgtccag cccaagaaga aggacaaaaa gaagaaaaac gtgctgctcg
     1801 tccacgtcgt ccaagacgtc aagaaaagcg tgatttcgaa cttccagaaa cacaaacagg
     1861 attttcaatg gctgatttgt ttggtgatat cgaactttaa tcaaattgaa aattcacaaa
     1921 atcctttgtt tactaaacaa gggatttttc tggctctttg tcaactgtag tgggttgaag
     1981 tcagctaagc tcgagaaagg acaaatttcg tcctttcttt tttgatgttc aaagcgataa
     2041 aaatccgttt tttgaagttt tcaaagtttc gaaaaccaaa ggcattgcgc ttgataagtt
     2101 tgatgagatt attggtcgct tccagtttgg cattagaata gtgtagttga agggcgttga
     2161 taatcttttc tttatctttg aggaaggttt taaagacagt ctgaaaaata ggatgagact
     2221 gcttaagatt gtcctcaata agtccgaaaa atttctctgg ttccttattc tggaagtgaa
     2281 acagcaagag ctgatagagc tgatagtggt gtttcaagtc ttgtgaatag ctcaaaagct
     2341 tgtctaaaat ctctttattg gttaaatgca tacgaaaagt aggacgataa aatcgcttat
     2401 cactcagttt acggctatcc tgttgtatga gcttccagta gcgcttgata gccttgtatt
     2461 catgggattt ttgatgaaac tgattcatga tttgaacacg cacacgactc atagcacggc
     2521 taagatgttg tacaatgtga aagcgatcaa gaacgatttt agcattcggg agtgaaacag
     2581 tctgggagac tgtttcagcc tgagcctaga aatttgaaag cgaagctgtt tagccaagtc
     2641 atagtaagga ctaaacatat ccatagtaat gattttgacg cgacatcgga cggctctatc
     2701 atatttaaga aagtgatctc ggatgacagc ttgtgttctg ccttcaagaa cagtgatgat
     2761 attgagattg ttaaaatctt gcgcaataaa gctcatctcc atctcccgat tgaaacagtc
     2821 actccccgga ctgtttcaac gtcccaggac ataatctcag gaagacgcga aaaatcatgc
     2881 tcaaagtgag aatcattgag ctttcgaatg acagttgaag ttgaaatggc cagctgatga
     2941 gcaatatcgg tcatagaaat cttctcaatc aacttttgcg caattttttg gttgataata
     3001 cgaggaattt gatgattctt cttgacgata gaagtttcag cgaccatcat tttagaacaa
     3061 tgatagcact tgaaacgacg ctttctaagg agaattctag taggcatacc agtcgtttca
     3121 agataaggaa ttttagaagg tttttgaaag tcatatttct tcatttgact tccgcactca
     3181 ggacaagatg gagcttcata gtccagtttg gcgatgattt ccttgtgtgt atccttattg
     3241 acgatgtcta aaatctggat attagggtct ttaatgtcta gtaattttgt gataaaatgt
     3301 aattattcca tatgattctt tctaatgagt tgttttgtcg cttttcatta taggtcatat
     3361 gggacttttt ttctacacaa aaataggctc cataatatcc ataggggatt tacccactac
     3421 aaatattata gagcccaaaa tcctttgttt actaaacaag ggatttttct tttgtctctg
     3481 ctcctttttt gatataatag ttctatgtta aaatcagaaa aacaatcacg ttatcaaatg
     3541 ttaaatgaag aattgtcctt cctattggaa ggcgaaacca atgttttggc taatctttcc
     3601 aacgccagtg ctctcataaa atcacgtttt cctaataccg tatttgcagg cttttatttg
     3661 ttcgatggaa aggaattggt tttaggcccc ttccaaggag gtgtttcctg catccgtatt
     3721 gcactaggca agggtgtttg tggtgaggca gctcactttc aggaaactgt tattgttgga
     3781 gatgtgacga cctatctcaa ctatatttct tgtgatagtc tagctaaaag tgaaattgtg
     3841 gtgccgatga tgaagaatgg tcagttactt ggagttctgg atctggattc ttcagagatt
     3901 gaggattacg atgctatgga tcgagattat ttggaacaat ttgtcgctat tttgcttgaa
     3961 aagacagcat gggactttac gatgtttgag gaaaaatctt aatgtatcaa gcactttatc
     4021 gaaaatatag aagtcaaaac ttctcccagt tagttggtca agaagttgtg gctaagactc
     4081 ttaaacaagc ggtggagcaa gagaaaataa gtcacgctta tcttttttct ggtcctcgtg
     4141 gaacgggaaa aaccagtgtt gctaaaatct ttgccaaggc tatgaactgt cccaatcaag
     4201 tgggtggcga accttgcaat aactgctata tttgtcaagc agtgacggac ggtagtttag
     4261 aagatgtcat tgaaatggat gcagcttcta ataatggggt agatgaaatt cgcgaaattc
     4321 gtgataaatc tacctatgcg cctagccttg ctcgttataa ggtttatatc atagatgagg
     4381 ttcacatgct gtctacaggg gcttttaatg ccctcctaaa gacgctggaa gaaccaacac
     4441 agaatgtagt ctttattttg gccactactg aattgcacaa gattcctgct actattctat
     4501 cccgtgtgca acgttttgag tttaaatcaa ttaagacaca ggatattaag gaacatattc
     4561 actatatctt agaaaaagaa aatatcagtt ctgaaccaga ggctgtggaa atcattgcca
     4621 gacgggcgga aggtggaatg cgggacgcct tgtctatttt ggatcaagcc ctgagtttga
     4681 cacagggaaa tgagctgacg actgctatct ctgaagaaat tactggcacc attagcctat
     4741 cagccttgga tgattatgtg gcggccttgt ctcaacagga tgttcccaaa gctttgtctt
     4801 gcttgaatct tctttttgac aatggtaaga gcatgactcg ttttgtgacc gatcttttgc
     4861 actatttaag agacttgtta attgttcaaa cagggggaga aaatactcat catagttcag
     4921 tctttgtaga aaatttggca cttcctcaaa aaaatctgtt tgaaatgatt cgcttagcaa
     4981 cagtgaattt agcagatatt aagtctagtt tgcagcccaa gatttatgct gaaatgatga
     5041 ccgtctgttt ggcggaaatc aagcccgaac cagctctatc aggagcggtt gaaaatgaaa
     5101 ttgctacgct gagacaggaa gttgcccgtc tcaaacaaga gctttctaat gcaggtgcgg
     5161 ttcctaaaca agttgcacca gctcctagtc gaccagctac gggcaaaaca gtctatcgtg
     5221 tcgatcgcaa taaagtgcaa tctatcttac aagaggccgt cgaaaatcct gatttagcac
     5281 gtcaaaatct aattcgtttg cagaatgcct ggggagaggt aattgaaagt ctaggtgggc
     5341 cggacaaggc tctgctagtt ggttctcaac cggttgctgc caatgaacac catgctattc
     5401 ttgcttttga gtctaacttc aatgctggtc aaactatgaa acgagacaat ctcaatacca
     5461 tgtttggtaa tatcctcagt caggcggcag gtttttcacc tgagatttta gctatttcca
     5521 tggaggaatg gaaagaagtt cgcgcagcct tttcagccaa agccaaatct tctcaaactg
     5581 aaaaagaagt agaagaaagc ctgattccag aaggatttga atttttggct gataaagtga
     5641 aggtagagga agactaaaga aagatttcat gatacaataa gtttatgaat aaacaacaat
     5701 ttattattat ggcgctattt acagctgctg agacctattt tttcaatgaa gcctggatga
     5761 ctggccgcta tattatggca gccttttggg caattttact ctttagaaat ttccgagtca
     5821 gttatgtgat gggtaaaatt gttgatgtca tcgatcagca ttttaatagg aaagactagc
     5881 cctcagcttc cagacaaaat caaagccttt taggcttttt tttgttatac tagaaaagta
     5941 tatttataga atttttgctc tatttctggg gaaatcagac gtttttctag taagtactgt
     6001 aaaagttttg aaaaagaaag gaactatcat gtcagtaata gagatcaaag atcttcacgt
     6061 tgagattgaa ggaaaagaaa ttttaaaagg ggttaacctg accctgaaaa caggagaaat
     6121 tgccgctatc atgggaccaa atggtacagg taaatcgact ctttctgccg ctatcatggg
     6181 aaatccaaac tatgaagtaa ctaaaggtga agttttgttt gatggcgtaa acatccttga
     6241 gttggaagtg gatgagcgtg cgcgtatggg acttttcctt gctatgcaat acccatcaga
     6301 aatccctgga attaccaatg ctgagtttct tcgtgccgct atgaatgcgg gtaaagaaga
     6361 tgatgagaag atttcagttc gtgagtttat tactaagcta gatgaaaaaa tggaattgct
     6421 caacatgaaa gaagaaatgg cagagcgtta cctcaacgaa ggcttctctg gtggtgagaa
     6481 aaaacgcaat gaaattcttc aacttttgat gttggagcca acatttgctc ttttggacga
     6541 gattgactca ggtcttgata ttgacgctct taaagttgtg tctaaaggtg tcaatgccat
     6601 gcgtggtgaa ggttttggtg ctatgatcat cactcactac caacgtcttt tgaactatat
     6661 cacacctgat gtggtacacg tgatgatgga aggtcgtgtt gtcctttctg gtggtccaga
     6721 attggctgcg cgtttggaac gtgaaggata cgcaaaacta gctgaagaac ttggctacga
     6781 ctacaaggaa gaattgtaat tccctcgtat cttttaggag aagtaaatga ctagagaaaa
     6841 tattaaactt ttttcagaaa tgcacgctga accaagctgg ttggctgatc tccgtcaaaa
     6901 agcttttgac aagattgaga ctttggaatt accagttatt gagcgtgtca aattccaccg
     6961 ttggaatctg ggtgatggaa cgattacaga aaatgagcca tcagcaaatg ttccagattt
     7021 cacagcttta gatcatcact tgaagttggt gcaagtagga actcaaactg ttttcgaaca
     7081 aactccagtt gagttagctg aacagggtgt tgtcttcaca gactttcact cagctttaga
     7141 agaaattcca gagctgatcg aagaattctt catgtcatct gttaagtatg atgatgacaa
     7201 gttggcggct taccacacag cttactttaa cagtggtgct gtactctata ttccagataa
     7261 cgtagaaatc acagagccaa ttgaaggaat tttctaccaa gatagcgata gcaatgtgcc
     7321 gtttaacaag catattatga ttatcgctgg taaaaattct aagattagtt atctggagcg
     7381 tttagagtca cgcggtgaag gaagtgacaa agtaactgcc aatatcacag tggaagtgat
     7441 tgcacgttct ggtgcgcaag tcaagtttgc tgctatcgac cgtctaggtg aaaacgtcac
     7501 tgcctacatt agccgtcgtg gtaaattagg caacgatgca agtattgact gggctatcgg
     7561 tgtcatgaac gaaggaaatg tcgttgctga ttttgatagt gacttgattg gtaatggtag
     7621 ccatgctgac ctcaaggttg tagctctttc aagtggtcgt caggtacaag ggattgatac
     7681 tcgtgtaact aactatggct gcaactctat cggaaatatc ctacaacatg gggttatcct
     7741 tgaaaaagca actttgactt tcaatggtat cggccacatc atcaagggtg ctaagggagc
     7801 agatgcgcaa caagagagcc gtgttctcat gctttcagac caagcgcgtt cagatgctaa
     7861 cccaattctt ttgattgatg aaaatgatgt cactgcagga cacgcagcgt ctatcggaca
     7921 agttgatcca gaagacatgt attacctcat gagtcgtgga ttggataagg caactgcaga
     7981 gcgtttggtt gttcgtggtt tccttggatc tgttatcgtg gagattccag tcaaggaagt
     8041 tcgtgatgaa atgattgcaa ctatcgaaga gaaattgtca aaacgctaag gggaagccta
     8101 tgttagatgt agaagcgatt cgcaaggatt ttccaatttt agatcagatt gtcaatgatg
     8161 aacctctggt ctatctggac aatgctgcga cgacacaaaa accactagta gttctgaaag
     8221 ctattaacag ttactatgag caggacaatg ccaatgttca ccgtggtgtc cataccttag
     8281 cggaacgagc gacagcttct tatgaagctg ctcgtgaaac cattcgtaag tttattaatg
     8341 caggctctac aaaggaagtt ctctttacca gaggaacgac aaccagcctt aactgggtgg
     8401 cacgctttgc tgaggaaatt ctcgctgagg gagaccgggt cttgatttca gtaatggaac
     8461 accattctaa tatcattcca tggcaggaag cttgtcgaaa gactggagca gagcttgtct
     8521 atgtctatct taaagacggt gccttggata tggaggattt gcgagctaaa ttgactgata
     8581 aggttaaatt tgtttcccta gctcatgcct ccaatgttct tggtgtggtc aatccgatca
     8641 aggaaatcac tcaattagcc caccaagttg gggcaattat ggtagtggat ggtgctcaat
     8701 ctacacctca tatgaagatt gatgtccagg acttggatct ggactttttc gccttttcgg
     8761 gtcacaagat ggctggtccg actggtatcg gtgtccttta cggcaaagaa aagtatcttg
     8821 agcaaatgtc tccagtagaa tttggcggcg agatgattga ttttgtctac gagcaatttg
     8881 ctagttggaa ggaattgcct tggaaatttg aggctggaac gccaaatatg gcaggagcta
     8941 ttggacttgc gactgcagtt gattatctgg aaaagattgg tatggatgcc gttgaagctc
     9001 atgaacagga attgattgcg tacgtctatc caaaactgca ggcaattgag ggattgacca
     9061 tttacggttc tcaggatttg gctcaacgtt cgggtgttat tgcctttaac ctaggtgatc
     9121 tccatcctca cgatcttgcg acggctctgg attatgaagg agtggctgtt cgtgctggtc
     9181 accattgtgc gcaacccttg cttcagtatt tggaagtccc agcaacagct cgtgcaagtt
     9241 tttatatcta caataccaag gcagattgcg acaaactagt cgatgcccta caaaagacaa
     9301 aggagttttt caatggcact ttctaaacta gatagccttt atatggcagt ggtagcagac
     9361 cattcgaaaa atccacatca ccaagggaag ttagaagatg ctgagcaaac cagtctcaac
     9421 aatccgactt gtggggatgt catcaacctc tctgtcaagt ttgatgcaga ggaccgtttg
     9481 gaagatattg cttttctaaa ttcaggatgc acgatttcaa ctgcttctgc tagtatgatg
     9541 acagatgccg ttttaggaaa aaccaaacaa gaaattttag aactggcgac tattttttct
     9601 gaaatggttc aagggcaaaa agatgagcgt caaggccaac ttggagacgc ggcattcttg
     9661 tcaggtgttg ccaaattccc tcaaagaatc aagtgtgcaa ccctagcttg gaatgccctt
     9721 aagaaaacaa ttgaaaatca agaaaaacag taagacaagt ttcttttgtc ttatgaatta
     9781 ttagaaatga agaaagaaag gatactatgg ctgaagaaag agtagaacca aaaccaattg
     9841 accttggtga atataaattt ggtttccatg acgatgtaga gcctgtctta tcgacaggaa
     9901 aaggactcaa cgaaggtgtt attcgtgaat tatctgctgc taagggtgag cctgagtgga
     9961 tgttggagtt ccgtttgaag tcttatgaaa ccttcaaaaa aatgcccatg caaacttggg
    10021 gagcagactt gtcagagatt gactttgatg acttaatcta ctaccaaaaa ccatctgaca
    10081 aaccagcccg ttcttgggat gatgtacctg aaaagattaa agaaaccttt gaacgtatcg
    10141 ggattccaga agctgaacgt gcttatttag caggggcttc tgcccagtac gagtcagaag
    10201 tggtttacca caacatgaag gaagagttcc aaaaattagg tattatcttt acagatacag
    10261 attccgcact caaggaatac ccagacttat ttaaacaata ctttgcgaag ttggtaccgc
    10321 cgacagataa caagttggca gccctcaact cagcagtatg gtcgggtgga acttttatct
    10381 acgtgccaaa aggtgtcaag gtagatattc cacttcaaac ttatttccgt atcaataacg
    10441 aaaatatagg tcagttcgaa cgtaccttga ttatcgttga tgagggagca agcgtccact
    10501 acgtagaagg atgtacagca ccaacatatt caagcaatag cttacacgct gccattgtag
    10561 aaatttttgc tttggacgga gcttatatgc gttatacaac tatccaaaac tggtctgata
    10621 acgtctataa cttggtaaca aagcgtgcta aggctcaaaa ggatgctact gttgagtgga
    10681 ttgatggaaa cttgggtgcc aaaacgacta tgaaatatcc atctgtttac cttgatggag
    10741 aaggagcgcg tggtaccatg ctctctatcg cctttgctaa tgcagggcaa caccaagaca
    10801 cgggtgctaa gatgattcac aatgctccac ataccagctc gtctattgtg tctaaatcca
    10861 tcgctaaagg tggaggaaag gttgactacc gtggacaagt cacctttaac aagaactcta
    10921 agaaatctgt ttcccacatt gaatgtgata ccattatcat ggatgacttg tcagcatcag
    10981 atactattcc atttaatgaa attcacaact cgcaagtggc tttggaacac gaagccaaag
    11041 tatctaagat ttcagaagag caattgtatt atctcatgag ccgtggattg tcagaatctg
    11101 aggcaactga aatgattgtc atgggatttg tagaaccctt tacaaaagaa cttccaatgg
    11161 aatacgcagt tgagctgaac cgcttgatta gctatgaaat ggagggatca gttggataaa
    11221 atttgatttt atactcttcg aaaatctctt caagccacgt cagcatcgcc ttaccgtatg
    11281 tatggttact gacttcgtca gtttcatcta caacctcaaa acagtgtttt gagcaacctg
    11341 cggctagctt cctagtttgt tctttgattt tgagtattag atttactcaa aatcaaggat
    11401 tttgaagatg aacttgtatc aaaaaatcgc ggtttaaaat cgcgattttt tataatttct
    11461 cgttaacaaa gcggacaaac tgattccacc aaacttttaa gaagaaggct ttttcaattt
    11521 tcttgtctgc taccatttcg aaactagggc gctctgtggt gatgtaacct tgaccaatca
    11581 agtccttgtc ttcataagtc aaatggccaa ccactgttcc agcttcaagt ggtgctggga
    11641 ttgctttgga atcaggtgtg aattgaacag attgggaaga ttgattccca atctgttcga
    11701 ttagatagat atcctctgga gccactgcag ttactgtatc ttcttttcca tcttgtacag
    11761 gggctttgct atcttgatag gcatcgcctt gttgaacgat tttgcgaagt gtaaatgtag
    11821 aagaaatata atccattagg gaagatgtag ctgtaaatcg agcgtaagga ttattgtctt
    11881 gatgatctgc atttaaaaca actgtgatga ctctcatgcc tttttcgaca gtagtaccaa
    11941 caaaagactc tccagcctta tctgttgttc ctgtttttag cccatcaaaa ccaccacggt
    12001 aagcaggcat accttctaac atgtagttgg ttgaagtgat tgtcatccca gcaaaagtag
    12061 aagaaggttt tttagtgatt tctaagactt gtgggtattt tttgatgagg ttgcgagcaa
    12121 cgatagcgac atcataagca ctaagcttat tttcctcatc ttttttagaa cctgggtaaa
    12181 tgttatcccc tagagtttca ttgttaagac ctgtcgtatt gacaacagtg gcatcctgaa
    12241 ttccccattc caagagtttt gcccgcatca tatcgacgaa atctttttct gagccagcaa
    12301 ttttctcagc tagggcaata gcggcgctgt tggcactaga taccagagtt gcttcaagca
    12361 actcttcgac agtataatta cgggcctcca taggaatatt actggcttca gaatttgtcg
    12421 tcaattgata aggataatca gaaatatcta caggagtgga gagggtaata cttccgtttt
    12481 ccaaagcttc atagaccaga taaacagtaa tcaattttgt tatggaagca atttcgacag
    12541 gttgcgttgc atccttctca tagagaattt taccagtatt tgcctcaaca gcaatcgcat
    12601 gtttagcggc aatggtaaaa tcttgagcaa cagcagtaga agcaccccct aaaagagaga
    12661 cagttaacaa agttaaaaat atttttttca tagtagtctt attctatcat aaagaaaaaa
    12721 aatattcttg ctttaataat tcatctgtta agctttttga aaatatggta aaataaagtg
    12781 agggaggtaa ctcatgtttc gtagaaataa attatttttt tggaccacag aaattttact
    12841 cttaaccatc atcttttacc tatggagaca gatggggtct ttgattaacc cttttgttag
    12901 cgtgcttaat acaattatga ttccattttt attaggaggc tttctttatt atttgacaaa
    12961 ccctattgtt actttcttaa ataaagtctg taaactcaat cgtttgcttg gtattttaat
    13021 taccttgtgt actttggtct ggggaatggt cataggtgtt gtctatctct tacctatttt
    13081 gattaatcag ttatctagtt tgattatatc tagtcaaact atttatagtc gagtacaaga
    13141 cttaatcata gacttatcta attatcctgc gctccagaat ttggatgtag aagctacaat
    13201 tcagcagtta aacttatcct atgtggatat tcttcaaaat atcctaaata gcgtatcaaa
    13261 tagtgtgggg agcgtcttgt cagctcttat cagtactgtt ttgattttga ttatgactcc
    13321 agtttttttg gtttatttct tattagatgg acataaattc ttgcccatgc ttgaaagaac
    13381 gattctaaag agggatcgct tgcatattgc aggcttatta aagaatttaa atgcgacgat
    13441 tgctcgctat attagtggag tttcgattga cgcaatcatt ataggttgtt tggcttatat
    13501 tggctatagt attattggtt taaaatatgc tttagttttt gccatttttt ctggtgtagc
    13561 caatttaatt ccttatgtgg ggccaagtat tggtttgatt cctatgatca tcgcaaatat
    13621 attcactgat ccccatagac tgctgattgc agtgatttat atgcttgttg ttcagcaggt
    13681 agatggcaat atcttatatc ctcgaatcgt aggaagtgtt atgaaggttc atccaatcac
    13741 gattttagtt ttacttttgt tgtcaagcaa tatctatggt gtagttggaa tgattgtcgc
    13801 agtgccaacc tattctatct tgaaagaaat ttctaagttc ttatcccgtt tgtatgaaaa
    13861 tcataaaata atgaaagaac gagaaagaga attagctaag taaaagtcag gagaaccctg
    13921 atttttcttt actggaagtg gcctttagat tagaagactg aaaataagtt aaagtcttaa
    13981 actaattttc acagctaaga atagtagaag ttaatctgat aaaaatcgaa aaaaccagtg
    14041 gaattctgtg tcagggtaag ttccactggt tttcatagtc tattaaagtt cgaatgaaac
    14101 ctatttatag tagattgaaa ctagaatagt acac
//
LOCUS       DAVLXH010000051        14032 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00028199
            SAMN33607166-rid17955573.denovo.051, whole genome shotgun sequence.
ACCESSION   DAVLXH010000051 DAVLXH010000000
VERSION     DAVLXH010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607166
            Sequence Read Archive: SRR23725544
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14032)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14032)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721421.1
            Genome Coverage       :: 115x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:42:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,210
            CDSs (total)                      :: 2,161
            Genes (coding)                    :: 2,023
            CDSs (with protein)               :: 2,023
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 73 of 138
            Pseudo Genes (incomplete)         :: 60 of 138
            Pseudo Genes (internal stop)      :: 40 of 138
            Pseudo Genes (multiple problems)  :: 31 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14032
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607166-rid17955573.denovo.051"
                     /strain="AUSMDU00028199"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1349"
     gene            complement(15..866)
                     /locus_tag="VYO11_001711"
     CDS             complement(15..866)
                     /locus_tag="VYO11_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV1596236.1"
                     /translation="MRWDYGQIFKEIRKSKGLTQQDVCGQVIHRTTLTNIEHGKVIPS
                     FENMVFLLEQIDMSLAEFKYICNEYHPSKRRDIIVESQNPSTFQDTRKMVELTEKCQK
                     YLKTHHDVPIQNIYRHTKIVTELRTKGFKNNHVLKDLYEEIWDYLEPMDTWYISDLKL
                     LGTILFFFPSENLPLLIDRIMKTIEKYKYFRETKAFLSSFLANLSTVYFQHHLFKECE
                     TITLQLLVLAEELKIYDILGFSQVRLGILQHNSDLIDKGITLLRLTKEEALVKILEKE
                     INDFSNL"
     gene            1193..1584
                     /locus_tag="VYO11_001712"
                     /pseudo
     CDS             1193..1584
                     /locus_tag="VYO11_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000694289.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            1606..2397
                     /locus_tag="VYO11_001713"
     CDS             1606..2397
                     /locus_tag="VYO11_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1596237.1"
                     /translation="MKIPLLTFARHKFVYVLLTLLFLALVYRDVLMTYFFFDIHAPDL
                     AKFDGQAIKNDLLKSALDFRILQFNLGFYQSFIIPIIIVLLGFQYIELKNKVLRLSIG
                     REVSYQGLKRKLTLQVASIPCLIYLVTVLIIAILTHFFGTFSPLGWNSLFSDGSSLQR
                     LLDGEITSYLFFTCVLLIGIFINAIYFLQIVDYVGNVTRSAITYLMFLWLGSMLLYSA
                     LPYYMVPMTSLMQASYGDVSLMKLFTPYILYIVPYMVLEKYEDNV"
     gene            2390..3031
                     /locus_tag="VYO11_001714"
     CDS             2390..3031
                     /locus_tag="VYO11_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000475766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1596238.1"
                     /translation="MFKNFNNIWLKRKIVLLLRIVLMMILINYLLSTAVQKQDAVIFF
                     KRELISIFSYNDYSEANLEIPKLLLNLSLFMVGWLSVILLESDLADHYHHLIRYQSSS
                     FFDYTRKRLVVISKFFTQDLLVWFLGLLPLGIHFKTVALFFLLAQLMMLYLLLSYLIA
                     LISAGAGFSFFLYFLAFVGQEWMMDHIVTVYLLLLSLLVMLIVSRLEEKFKKG"
     gene            3035..3685
                     /locus_tag="VYO11_001715"
     CDS             3035..3685
                     /locus_tag="VYO11_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV1596239.1"
                     /translation="MKLEIINGQKIYGKRPILNQLNLVFQSGKIYGLKGDNGSGKTVL
                     LKVLAGYIKLDKGKVLQDGKVYGIKNHYIQDAGILIEKVEFLSHLSLRENLELLRYFS
                     SKVTEKRIAYWIQYYDLQEFEDVEYRHLSLGTKQKMALIQAFISSPSILFLDEPMNAL
                     DEKSVRLTKQVILSYLKKENGLVILTSHISEDISDLCTDVLVVENGHIQYVKDIQS"
     gene            3696..3983
                     /locus_tag="VYO11_001716"
     CDS             3696..3983
                     /locus_tag="VYO11_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000940707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1596240.1"
                     /translation="MAHLKSFITRYSKVYIGLVLLIWLSFFFIPWDRAILGVRIDIFI
                     IQKVLLVFGILSILMALLSKKVSLFVFGLICCLSLWINLFITFAILPIFGN"
     gene            4129..6642
                     /gene="secA"
                     /locus_tag="VYO11_001717"
     CDS             4129..6642
                     /gene="secA"
                     /locus_tag="VYO11_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HEV1596241.1"
                     /translation="MANILKTIIENDKGEIRRLEKMADKVFKYEDQMAALTDDQLKAK
                     TVEFKERYQNGESLDSLLYEAFAVVREGAKRVLGLFPYKVQVMGGIVLHHGDVPEMRT
                     GEGKTLTATMPVYLNALSGKGVHVVTVNEYLSERDATEMGELYSWLGLSVGINLATKS
                     PMEKKEAYECDITYSTNSEIGFDYLRDNMVVRAENMVQRPLNYALVDEVDSILIDEAR
                     TPLIVSGANAVETSQLYHMADHYVKSLNKDDYIIDVQSKTIGLSDSGIDRAESYFKLE
                     NLYDIENVALTHFIDNALRANYIMLLDIDYVVSEEQEILIVDQFTGRTMEGRRYSDGL
                     HQAIEAKEGVPIQDETKTSASITYQNLFRMYKKLSGMTGTGKTEEEEFREIYNIRVIP
                     IPTNRPVQRIDHSDLLYASIESKFKAVVEDVKARYQKGQPVLVGTVAVETSDYISKKL
                     VAAGVPHEVLNAKNHYREAQIIMNAGQRGAVTIATNMAGRGTDIKLGEGVRELGGLCV
                     IGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDDLMKRFGSERLKGIFERLNMSE
                     EAIESRMLTRQVEAAQKRVEGNNYDTRKQVLQYDDVMREQREIIYAQRYDVITADRDL
                     APEIQSMIKRTIERVVDGHARAKQDEKLEAILNFAKYNLLPEDSITMEDLSGLSDKAI
                     KEELFQRALKVYDSQVSKLRDEEAVKEFQKVLILRVVDNKWTDHIDALDQLRNAVGLR
                     GYAQNNPVVEYQAEGFRMFNDMIGSIEFDVTRLMMKAQIHEQERPQTERHISTTATRN
                     IAAHQASMPEDLDLSQIGRNELCPCGSGKKFKNCHGKRQ"
     gene            6723..7754
                     /locus_tag="VYO11_001718"
     CDS             6723..7754
                     /locus_tag="VYO11_001718"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000232189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HEV1596242.1"
                     /translation="MVFTAKSSKINIEEVRALSKLEGQALERKSQRDQELEAIIRGED
                     QRILLVIGPCSSDNEEAVLEYAKRLAVLQEEVADRIFMVMRVYTAKPRTNGDGYKGLI
                     HQPNATEAPSLINGIKAVRHLHYRVITETGMTTADEMLYPENLPLVDDLISYMAVGAR
                     SVEDQQHRFVASGAGFSTGFKNPTSGNLNVMFNGIYAAQNKQSFLFLGKEVETTGNPL
                     SHAILRGALNEYGKNIPNYYYDNLIDTIAQYEKMGLENPFIIIDTNHDNSGKQYIEQI
                     RIVRQTLINRAWNEKIKQFVRGFMIESYLEDGRQNEPEVFGKSITDPCLGWDNTEALV
                     REIYKTLGE"
     gene            7756..8787
                     /locus_tag="VYO11_001719"
     CDS             7756..8787
                     /locus_tag="VYO11_001719"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HEV1596243.1"
                     /translation="MAFIEKGQEIDMEVIKAETQLSADALRLKESRDRELADIISGED
                     DRILLVIGPCSSDNEEAVLEYARRLSALQKKVADKIFMVMRVYTAKPRTNGDGYKGLV
                     HQPDTSKAPSLINGLQAVRQLHYRVITETGLTTADEMLYPSNLILVDDLVSYHAVGAR
                     SVEDQEHRFVASGIDAPVGMKNPTSGNLGVMFNAIYAAQNKQTFLYHGQEVETSGNPL
                     AHVILRGAVNEYGNYMPNYYYENLLQAIERYETMGLENPFILIDTNHDNSGKQYMEQI
                     RIVRQTLQNRDWNEKIKKTVRGFMIESYLADGRQNQPEIFGCSITDPCLGWENTEALV
                     EEIYVTLTK"
     gene            8826..9194
                     /locus_tag="VYO11_001720"
     CDS             8826..9194
                     /locus_tag="VYO11_001720"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000061844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HEV1596244.1"
                     /translation="MRMIVGHGIDIEELASIESAVTRHEGFAKRVLTAQEMERFTSLK
                     GRRQIEYLAGRWSAKEAFSKAMGTGISKLGFQDLEVLNNERGAPYFSQAPFSGKIWLS
                     ISHTDQFVTASVILEENHES"
     gene            9184..10287
                     /locus_tag="VYO11_001721"
     CDS             9184..10287
                     /locus_tag="VYO11_001721"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000648075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HEV1596245.1"
                     /translation="MKASPHRPTKALIHLGAIRQNIQQMGAHIPQGTLKWAVVKANAY
                     GHGAVAVAKAIQDDVDGFCVSNIDEAIELRQAGLSKPILILGVSEIEAVALAKEYDFT
                     LTVAGLEWIQALLDKEVDLTGLTVHLKIDSGMGRIGFREVSEVEQAQDLLQKHGVCVE
                     GIFTHFATADEESDDYFNAQLERFKTILASMKEVPELVHASNSATTLWHVETIFNAVR
                     MGDAMYGLNPSGAVLDLPYDLIPALTLESALVHVKTVPAGACMGYGATYQADSEQVIA
                     TVPIGYADGWTRDMQNFSVLVDGQACPIVGRVSMDQITIRLPKLYPLGTKVTLIGSNG
                     DKEITATQVATYRVTINYEVVCLLSDRIPREYY"
     gene            10306..12321
                     /gene="recG"
                     /locus_tag="VYO11_001722"
     CDS             10306..12321
                     /gene="recG"
                     /locus_tag="VYO11_001722"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HEV1596246.1"
                     /translation="MNLHQPLHVLPGVGPKSAEKYAKLGIENLQDLLLYFPFRYEDFK
                     TKQVLELEDGEKAVLSGQVVTPASVQYYGFKRNRLRFSLKQGEVVFAVNFFNQPYLAD
                     KIELGATLAVFGKWDRAKASLTGMKVLAQVEDDLQPVYRLAQGISQASLVKVIKTAFD
                     QGLDLLIEENLPQSLLDKYKLMSRCQAVRAMHFPKDLAEYKQALRRIKFEELFYFQMQ
                     LQTLKSENRVQGSGLVLNWSQEKVTAVKVSLPFALTQAQEKSLQEILTDMKSDHHMNR
                     LLQGDVGSGKTVVAGLAMFAAVTAGYQAALMVPTEILAEQHFESLQNLFPNLKLALLT
                     GSLKAAEKREVLETIAKGEADLIIGTHALIQDGVEYARLGLIIIDEQHRFGVGQRRIL
                     REKGDNPDVLMMTATPIPRTLAITAFGDMDVSIIDQMPAGRKPIVTRWIKHEQLPQVL
                     TWLEGEIQKGSQAYVISPLIEESEALDLKNAIALSEELTTHFAGKAEVALLHGRMKSD
                     EKDQIMQDFKERKTDILVSTTVIEVGVNVPNATVMIIMDADRFGLSQLHQLRGRVGRG
                     DKQSYAVLVANPKTDSGKDRMRIMTETTNGFVLAEEDLKMRGSGEIFGTRQSGLPEFQ
                     VADIIEDFPILEEARKVASYISSIEAWQEDPEWRMIALHLEKKEHLD"
     gene            12637..13617
                     /locus_tag="VYO11_001723"
     CDS             12637..13617
                     /locus_tag="VYO11_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetylxylan esterase"
                     /protein_id="HEV1596247.1"
                     /translation="MKNPALLEEIKTYRGRDEVPEDFDAFWDGEVKNVSTPPSYHLEE
                     RDFHIPQVKCYELTFEGSKEGKVYARIVLPKSEEKVPLIFHFHGYMGRGWDWADMLGF
                     TVAGYGVVSMDVRGQSGYSQDGLRSPLGNTVKGHIIRGAMEGRDHLFYKDVYLDIYQL
                     VEIVASLSQVDEKRLSSYGASQGGALALVAAALNPRIQKTVAIYPFLSDFRRVIEIGN
                     TSEAYDELFRYFKFHDPFHETEEEIMATLAYIDVKNLAHRIQGEVKMITGLDDDVCYP
                     ITQFAIYNRLTCDKTYRIMPEYAHEAMNVFVNDQVYNWLCGSEIPFKYLK"
BASE COUNT         4130 a         2554 c         3123 g         4225 t
ORIGIN      
        1 agagttatta caaattatag gtttgaaaaa tcattaattt ctttttcgag tattttaact
       61 aatgcctctt ctttggttag tcgtaataaa gttattcctt tatcaatcaa atcggagtta
      121 tgttgtagta ttcccaagcg tacttgagag aatccaagaa tatcgtatat ttttaattct
      181 tctgctaata ccaaaagttg tagggtgatt gtttcacatt ctttgaataa atgatgttga
      241 aaatatacag tggagagatt ggctaaaaaa gatgataaaa atgcttttgt ttctcggaag
      301 tatttatatt tctcgatggt tttcataatt ctatcaataa gaaggggaag attttcagaa
      361 ggaaagaaaa agagaatggt tccaagcaat ttcaaatcac taatgtacca tgtatccata
      421 ggttcaagat agtcccaaat ttcttcatac aaatctttca agacgtggtt gtttttgaat
      481 cctttagttc gtaactctgt gacaattttt gtatgacgat agatattttg aataggaaca
      541 tcgtgatgtg tcttaagata tttttgacat ttctcagtga gttcaaccat ttttctagta
      601 tcttgaaaag tagacggatt ttggctctct acaataatat ctcgcctttt actaggatgg
      661 tattcgttgc atatatactt gaattctgcc aagctcatat caatttgttc aagaagaaat
      721 accatgtttt caaaactggg aataacttta ccgtgttcaa tatttgttag agttgttcga
      781 tgtatgactt gtccacatac atcttgttgg gtcaatcctt ttgactttcg aatttcttta
      841 aaaatttgtc cataatccca tctcatattg ttcctcctag gtaaatgtga atattttcta
      901 catttataaa aaacgtagaa aaaggtggta ttattatatc aaaaaggagg gaaaaagtca
      961 tgggctttaa aaaatatttg aagaatttac cgaaaaactc tggatttttg atttggagtt
     1021 ggattcaact tatctggttt gaaacatggt tttggggata aagaaattag agtctataca
     1081 taataagtaa aggaggaatt tgtatgatat accatcgttt agaataagtc tatatttaaa
     1141 atagaagtta taaggaatct tcttgaataa aaaatgaaag gaaacagaaa aaatgaaaat
     1201 taagaaatta ttgaaaatgg ttattcctgt tttaatgata agtgctgttg gaactacttt
     1261 cgtagaagca aatcagatag gtgcttttag taattttgtt attactacca gttataagag
     1321 aacaggttat ttgactaaaa aaatgaaggt gcggaatata tcatgaactt aaatccttgt
     1381 agaaatttac atcccatgac tgttaagcat cgtatagtaa attctaatgg agaagctcgt
     1441 agtggagaat cgttaacaac ctgtggtact cgttcaactc atggtaattg ggcaacggtt
     1501 ggctatgttt atgcagcaga tatggcaaga caaaattggt gggatttatc agctgccatt
     1561 tcaggtagtt ggtcaccaaa ttaattcgta aagtaggtat aatttatgaa gattcctctc
     1621 ttaacttttg caaggcataa atttgtttat gtcttgctta ctttgctttt tcttgctttg
     1681 gtttatcgtg atgttttgat gacttatttc ttttttgata ttcatgcgcc cgatctagct
     1741 aaattcgatg gacaagcaat taaaaatgac ttattaaaat cagcattaga ttttcgtatt
     1801 ctccagttca atctaggttt ttatcaatca tttattattc caatcatcat tgttttgcta
     1861 ggttttcaat atattgagct gaaaaataaa gttttacgat tgagtattgg aagagaagtg
     1921 agttatcaag ggttaaaaag aaagttgact ttgcaagttg caagtatccc ttgtttgata
     1981 tatttagtga ctgtgctgat aattgcaatt ttaactcatt tctttgggac tttttctcct
     2041 cttggatgga attctctatt ttctgatggg agtagtttac aaaggctcct agatggagag
     2101 ataacaagct atttgttctt tacttgtgtc ctactaatcg gtattttcat caatgcaatc
     2161 tattttttac aaatagttga ttatgtgggg aatgtgactc gttcggcaat cacctatttg
     2221 atgtttcttt ggcttggttc tatgctgctc tatagtgcct tgccttacta tatggttcct
     2281 atgacgagtt tgatgcaagc tagctatggg gatgtaagtt tgatgaaact ctttactcct
     2341 tatatccttt atattgtccc ttatatggtg cttgaaaaat atgaagataa tgtttaagaa
     2401 ttttaacaat atttggctaa agagaaagat cgttttacta cttcgtatag ttctgatgat
     2461 gattttgata aactatctat tgtcaacagc ggttcaaaag caggatgctg ttatcttttt
     2521 caagagagaa ttgatttcaa tcttttccta taatgactat tctgaagcga atttagaaat
     2581 ccccaaactc ttgttaaacc tttcgctttt catggtagga tggctctctg tcattttact
     2641 tgaaagtgat ttggcagacc attaccatca cttgattcgc tatcaatcaa gctccttttt
     2701 cgattataca aggaaacgat tggttgtcat ttctaaattt tttactcaag atttacttgt
     2761 ctggttcctt ggtttacttc cgctaggaat tcatttcaaa acagtcgcac ttttcttttt
     2821 acttgctcag ttaatgatgt tgtacttact actgtcttat ctgatagcac tgattagtgc
     2881 gggcgctggt ttttcctttt ttctctattt tttagcattt gtgggacaag aatggatgat
     2941 ggatcatatt gtaacagtgt atttactact cttaagctta ttagttatgt tgattgttag
     3001 tcgcttggaa gagaaattta agaaaggata aacgatgaaa cttgaaatta taaatggaca
     3061 gaaaatttat gggaaaagac ctattttaaa tcagttgaat ttggtgtttc aatcaggaaa
     3121 aatttatgga cttaaaggtg ataatggatc tggcaagacg gttcttttaa aggtacttgc
     3181 tggttatatt aagcttgaca aaggaaaagt tcttcaagat ggtaaagttt acgggataaa
     3241 aaatcattat attcaggatg caggaatttt aattgaaaaa gtcgagtttt tatctcattt
     3301 atccctgaga gaaaatttgg aactgttaag gtatttttca tctaaagtta cggaaaaaag
     3361 aattgcctat tggattcaat actatgattt acaggaattt gaagacgttg aataccggca
     3421 tttatccttg ggaacaaagc aaaaaatggc cttgattcaa gcctttattt cctctccttc
     3481 tatactcttt ctcgatgaac ctatgaatgc tttggatgag aaaagtgtga ggttaaccaa
     3541 acaggtcatt ttatcttacc tgaaaaaaga aaatggtctg gttatcctga cgtcgcacat
     3601 atcggaagat atttcagacc tttgtacaga tgtattagtt gtcgaaaatg gacatataca
     3661 atatgtaaag gatatacaat cctaggagat ggcttatggc acatctaaaa tcatttatta
     3721 cacgctattc caaggtttat attggtttag ttctgctgat ctggctgtct ttcttcttta
     3781 tcccttggga tagagcgatt ctgggggtaa ggattgacat cttcatcata cagaaagtct
     3841 tgctagtttt tggaattctg tccattttga tggccttgct gtccaagaaa gtcagtctct
     3901 ttgtttttgg actgatttgc tgtctttctc tttggattaa cttatttatc acatttgcca
     3961 ttttgccaat ttttggcaat taaacagtca taaaagtcgg agaggttagc ttgaaaacta
     4021 acctcttttt ccttttcaaa atggggattc ttccttgaaa ataatcagta attgtgctaa
     4081 aattaaagga acattctaaa atattcggaa tttaaagtaa ggaaaaacat ggctaatatt
     4141 ttaaaaacaa ttatcgaaaa tgataaagga gaaatccgtc gtctggaaaa gatggctgac
     4201 aaggttttca aatacgaaga ccaaatggct gctttgactg acgaccaact aaaagcaaaa
     4261 acagttgaat ttaaggaacg ttatcaaaat ggagaatcac tggattcatt gctttacgaa
     4321 gcatttgcgg ttgtccgtga aggtgccaaa cgtgtcctag gtctcttccc ttataaggtt
     4381 caggtcatgg gggggattgt tcttcaccat ggtgacgtgc cagagatgcg tacaggggaa
     4441 gggaaaacct tgactgcgac catgccggta tacctcaatg ccctttcagg taaaggggtt
     4501 cacgtagtta cggttaatga atacctgtca gaacgtgacg cgactgagat gggtgaattg
     4561 tactcttggc ttggtttgtc agtagggatt aacttggcta ccaaatctcc aatggagaaa
     4621 aaagaagcct atgagtgtga tattacttac tcaactaact cagaaatcgg atttgactac
     4681 cttcgtgaca atatggtcgt tcgcgctgaa aacatggtac aacgtccgct taactatgcc
     4741 ttggtcgatg aggttgattc tatcttgatt gacgaggctc gtacaccttt gattgtatca
     4801 ggtgccaatg cggttgaaac cagtcagttg tatcacatgg cagaccacta tgtaaaatct
     4861 ttgaacaaag atgactacat catcgatgtg cagtctaaga ctattggttt gtctgattca
     4921 gggattgaca gggctgaaag ctacttcaaa cttgaaaacc tctatgacat cgaaaacgtg
     4981 gctttgaccc actttatcga taacgccctt cgtgccaact acatcatgct tctcgatatt
     5041 gactatgtgg tgagcgaaga gcaagaaatc ttgattgtcg accaatttac aggtcgtacc
     5101 atggaaggtc gtcgttattc tgatggattg caccaagcta ttgaagccaa agaaggtgtg
     5161 ccaatccagg atgaaaccaa gacatctgcc tcaatcacgt accaaaacct tttccgtatg
     5221 tacaaaaaat tgtctggtat gacgggtaca ggtaagactg aggaagaaga atttcgtgaa
     5281 atctacaaca ttcgtgttat tccaatccca acaaaccgtc ctgttcaacg tattgaccac
     5341 tcagaccttc tttatgcaag tatcgaatct aagtttaaag cggttgtcga agacgttaag
     5401 gctcgttacc aaaagggtca acctgtcttg gttggtacag tagcggttga aactagtgac
     5461 tacatttcta agaaattggt cgcagctggt gttcctcacg aagtcttgaa tgccaaaaac
     5521 cactatagag aagcccaaat catcatgaat gctggtcaac gtggtgccgt taccatcgca
     5581 accaacatgg cgggtcgtgg taccgacatc aagcttggtg aaggtgttcg tgaacttgga
     5641 ggactttgtg ttattggtac agaacgtcat gaaagtcgtc gtatcgataa ccagcttcgt
     5701 ggacgttcag gtcgtcaagg agatccaggt gagtcacaat tctacctatc tcttgaagat
     5761 gatttgatga aacgttttgg ttctgaacgc ttgaagggaa tctttgaacg tctcaacatg
     5821 tctgaagagg cgattgagtc tcgcatgttg acgcgtcagg ttgaagcagc tcagaaacgt
     5881 gtcgaaggaa ataactacga tacccgtaaa caagtccttc aatacgatga tgtcatgcgt
     5941 gaacaacgtg agattatcta tgctcaacgt tacgatgtca tcactgcaga tcgtgacttg
     6001 gcacctgaaa ttcagtctat gattaagcgc acgattgaac gtgtcgttga tggtcatgcg
     6061 cgtgccaaac aagatgaaaa actagaggca attttgaact ttgctaagta caacttgctt
     6121 cctgaagatt ctattacgat ggaagacttg tcaggcttgt ctgataaggc catcaaggaa
     6181 gagcttttcc aacgtgcctt gaaggtttac gatagtcagg tttcaaaact acgcgatgaa
     6241 gaagcagtta aagaattcca aaaagttttg attctacgag tggtggataa caagtggaca
     6301 gatcatatcg atgcccttga tcaattgcgt aacgcggttg gacttcgtgg ctatgctcag
     6361 aacaaccctg ttgttgagta tcaggcagaa ggtttccgta tgtttaatga tatgattggt
     6421 tcgattgagt ttgatgtgac acgcttgatg atgaaagcac aaattcatga acaagaaaga
     6481 ccacagacag aacgtcatat cagtacaaca gcgactcgca atatcgctgc tcaccaagca
     6541 agtatgccag aagatttgga tttgagccag attggacgca atgaactttg cccatgtggt
     6601 tctggtaaga aatttaaaaa ctgtcacggt aaaagacaat aaaatgagat agtttagagg
     6661 cggatatctt gtgaaaagta aatttttact gggtatccgt ttgctttata aggagatgag
     6721 ttatggtatt tacagcaaaa agctctaaaa taaatataga agaagttcgt gccttgtcaa
     6781 aattagaagg tcaggctttg gagaggaaat cacagcgaga tcaagagcta gaagccatta
     6841 tacgtggaga agaccagcga attctcttgg taatcgggcc atgctcatct gacaacgaag
     6901 aagctgtcct tgaatacgct aagcgtttgg cagtcctaca agaagaagtg gcagatcgta
     6961 tctttatggt tatgcgtgtt tatactgcca aaccccgtac caacggagat ggctataagg
     7021 gcttgattca ccagcctaac gcgacagaag cgcctagtct tatcaatgga atcaaagccg
     7081 ttcgccatct tcactatcgt gtcatcacag aaacagggat gacaactgct gatgaaatgc
     7141 tttatcctga aaaccttccg cttgtagatg atttgatttc ttacatggca gttggtgccc
     7201 gttcagttga agaccagcaa caccgctttg tggcaagtgg ggcaggattt tctactggtt
     7261 ttaaaaatcc aacctctgga aatctcaatg tcatgtttaa tgggatttat gctgctcaaa
     7321 acaaacaaag tttccttttc ttaggaaaag aagtagaaac aactgggaac ccgctttcac
     7381 acgctattct tcgtggtgct cttaatgagt atggaaaaaa tattcccaac tactattatg
     7441 acaatttaat tgataccatt gcccagtatg agaaaatggg cttggaaaat ccttttatca
     7501 tcattgatac caatcatgac aattctggta agcagtatat tgaacagatc cgaattgtcc
     7561 gccagacctt gattaaccgt gcttggaatg aaaaaattaa gcagttcgtt cgtggtttta
     7621 tgattgagtc ttatctggaa gatggtcgac aaaatgagcc agaagtattt ggtaagtcta
     7681 tcacagaccc ttgcctgggt tgggataaca cagaagctct tgtcagagaa atttacaaaa
     7741 cgttaggaga ataagatggc atttattgaa aaaggtcaag aaatcgatat ggaagtcatc
     7801 aaggctgaaa cccaattgtc tgcggatgcc ttgagactca aggaaagccg tgacagggaa
     7861 ttggcagata ttatttcagg ggaagatgac cgtattctct tggtgattgg tccttgctct
     7921 tctgataatg aagaggcggt cttggaatat gctcgccgtt tatccgcctt gcaaaagaag
     7981 gtagcggaca agattttcat ggtcatgcgc gtgtatactg ctaagcctcg taccaatgga
     8041 gacggctata aaggattggt tcaccagcca gatacttcta aggctccaag cctgattaac
     8101 ggcttgcagg ctgtgcgcca gttgcactac cgcgtgatta cagagactgg tttgacaacg
     8161 gcagatgaga tgctttatcc gtcaaatctg atcttggtgg atgacttggt cagctaccat
     8221 gccgttggag ctcgttctgt ggaagaccaa gagcaccgct ttgtggcttc tgggattgat
     8281 gcaccagtag ggatgaaaaa tccaacctca ggaaatttgg gtgttatgtt taacgccatc
     8341 tatgctgctc aaaacaagca aaccttcctt tatcatgggc aggaagttga gacatcaggt
     8401 aatcctttgg cccatgttat cctccgtgga gcagtcaacg agtatggcaa ttatatgccg
     8461 aattactact atgaaaacct actccaagcc attgaacgct atgaaaccat gggacttgaa
     8521 aatcctttta tcctcattga caccaaccat gataactcag gcaagcaata tatggagcag
     8581 attcgaattg ttcgccagac cttgcagaat cgtgattgga atgagaaaat taaaaagacg
     8641 gttcgaggat ttatgattga atcttaccta gcagatggtc gtcaaaacca accagagatc
     8701 tttggttgct ctattactga cccttgccta ggttgggaaa atacagaggc cttggtagaa
     8761 gagatttatg ttaccttgac aaaataagtg aaaaggatgg agttggggaa tctcaactcc
     8821 ttttgatgag aatgatagtt ggacacggaa ttgacatcga agaattggct tcgatagaaa
     8881 gtgcagttac acgacatgaa ggatttgcta agcgtgtact gaccgctcag gaaatggagc
     8941 gcttcaccag tctcaaagga cgcaggcaaa tagaatattt agctggtcgc tggtcggcta
     9001 aggaggcctt ttccaaggct atgggaacgg gcattagcaa gctcggtttt caggatttgg
     9061 aagtcttgaa caatgaacgt ggggcgcctt attttagtca ggcaccattt tcaggaaaga
     9121 tttggctgtc tatcagccac accgatcagt ttgtgacagc cagtgtcatt ttggaggaaa
     9181 atcatgaaag ctagtccaca tagaccaacc aaggctctga ttcatctggg agctattcga
     9241 caaaatattc agcaaatggg ggctcatatc cctcaaggaa cgctcaagtg ggctgtggtc
     9301 aaggccaatg cttatggtca tggagctgtt gccgttgcca aggcaattca agatgatgtt
     9361 gatggctttt gcgtttccaa tatcgatgaa gccattgaac tcagacaagc tggactcagc
     9421 aagccaatcc tcattttagg agtttctgaa atcgaagctg ttgctctagc taaagaatat
     9481 gacttcacct tgacagtggc tggactggag tggattcaag cactcttaga taaggaagtg
     9541 gacctaactg gattgacagt ccacctcaag attgattcag ggatgggacg gattggtttt
     9601 agagaggtca gtgaggttga gcaggctcaa gatttgctcc aaaaacacgg tgtttgtgtt
     9661 gaaggaatct ttacccactt tgctactgct gatgaggaat cagatgacta ttttaatgcc
     9721 cagttagaac ggtttaaaac tattttagct agtatgaagg aagttccaga gctggttcat
     9781 gctagcaatt ctgcaacgac tctttggcat gtagagacta ttttcaatgc ggttcgtatg
     9841 ggagatgcca tgtatggcct caatccaagt ggagcggtct tggatttgcc ttatgatttg
     9901 ataccggcct tgaccttgga gtctgctctg gttcatgtca agacagttcc agctggagct
     9961 tgcatgggct atggagcaac ttatcaagcg gatagcgagc aagtcatcgc gaccgtgcca
    10021 atcgggtatg cagatggatg gacaagagac atgcaaaatt tctctgtctt ggtagatggc
    10081 caagcttgcc caattgtcgg cagggtttcg atggaccaaa tcactattcg attgcctaag
    10141 ctttatccgc taggaaccaa ggtaaccttg attggctcca atggggataa ggaaatcact
    10201 gcaactcagg tagcgaccta ccgcgtcacc attaactatg aggtggtttg cctcctcagc
    10261 gaccgtattc cgagagaata ttattagaaa agaaaggagt ggagcatgaa tctacatcaa
    10321 cccttgcatg tcttgcctgg tgtgggacca aagtcagcag aaaaatacgc caaactagga
    10381 attgaaaact tgcaagatct cttgctctac tttcctttcc gttatgaaga cttcaaaacc
    10441 aagcaggtgc tggaactaga agacggtgag aaggcagttc tttctggtca ggtagtgact
    10501 cctgctagtg tccagtatta tggtttcaag cgcaatcgcc tgcgttttag tctcaagcag
    10561 ggagaggtcg tttttgcggt gaatttcttt aaccagccct atctggctga taaaatagag
    10621 ttgggagcaa cccttgctgt ctttggaaaa tgggaccgcg ctaaggctag tctgactggg
    10681 atgaaggttc tggctcaggt agaagatgac ctccagcctg tctatcgtct ggctcaggga
    10741 atcagtcagg ccagtctggt taaggtcatc aagacggctt ttgatcaggg actggacctc
    10801 ttgatagaag aaaatctgcc ccagtcttta ctagacaaat acaaactcat gtcccgttgt
    10861 caggcagtcc gagctatgca ttttccaaag gatttggcag aatacaagca ggctcttcgc
    10921 cgtatcaagt ttgaggaact cttttatttc caaatgcagt tgcagacgct caagtctgaa
    10981 aatagagttc agggaagtgg tctggttctg aattggtctc aggaaaaagt gacagcagtt
    11041 aaagtaagtc ttccttttgc cctgacccaa gctcaggaaa agagtttgca ggaaatttta
    11101 actgatatga agtccgacca ccacatgaat cgtctcctac aaggggatgt ggggagtgga
    11161 aaaacggtag tcgctggctt ggccatgttt gcggcagtga cagcaggtta tcaggctgcc
    11221 ctaatggtac caacagaaat cctcgcagag caacactttg agagtttaca gaaccttttt
    11281 cccaatttga aactggctct cttgacaggt tccttgaaag ctgcagaaaa gagagaggtc
    11341 ttggagacca ttgccaaggg tgaggctgat ttgattatag gaactcacgc tctgatacaa
    11401 gatggggtgg agtatgctcg tcttggtttg attattatcg atgagcagca ccgttttggt
    11461 gtagggcaaa ggcgtatttt acgggaaaaa ggtgacaatc cagatgtcct catgatgacg
    11521 gcgactccca ttccacggac gcttgccatc acagcctttg gagatatgga tgtttccatt
    11581 atcgaccaga tgccagcagg tcggaagcct attgtgacgc gctggatcaa acatgagcaa
    11641 ctacctcagg tcttgacttg gttagagggg gaaattcaaa aaggttccca agcctatgtc
    11701 atctctcctt tgattgaaga atcagaagct ctagatttga aaaatgccat tgccttatca
    11761 gaggagttga cgactcattt tgcaggcaag gcagaggtgg ctcttctaca tggtaggatg
    11821 aagagtgacg aaaaagacca gatcatgcag gatttcaagg agagaaagac ggatattctg
    11881 gtttcgacga cggttattga ggttggggtc aacgttccca atgcgactgt catgattatc
    11941 atggatgccg atcgcttcgg tctcagtcaa cttcaccagc ttagaggtcg tgtcggtcgg
    12001 ggggacaagc agtcctacgc tgttctcgtt gccaatccca agacggattc tgggaaagac
    12061 cgcatgcgca tcatgacaga aacgaccaat ggatttgtcc ttgcggagga agatttgaaa
    12121 atgcgtggtt ctggtgagat ttttggaacc agacagtcag gacttccaga gttccaagtg
    12181 gctgatatta tcgaagattt tccgatttta gaagaagcaa gaaaggttgc tagctacatt
    12241 agttctatag aagcttggca agaagatcca gagtggcgca tgattgccct tcatctggaa
    12301 aagaaagaac atctggatta agctttctct aaggaaaact taagctagtt tttaggtttg
    12361 gctcttatac taaagtcatc aaaaagaaac gaggactctc atatgacagt aacgattaaa
    12421 gtaaattacc aaaccacttt ccaaaagaag gaagcaaaaa actagtataa acagaagaga
    12481 gagcgaaatg ctctttttcg tttctaaaac tactttcagc ccatcatcct aaaagtaaag
    12541 aatctaaatt cactttctat ttatccttct ttcttgcatt gattacatag atatgctaca
    12601 gttgtggtaa cgattacaaa ataaaaggag catgctatga aaaatccagc tttgctagaa
    12661 gaaattaaga cctatagagg aagggatgag gttccggaag actttgatgc tttctgggat
    12721 ggggaagtga aaaatgtttc cacacctcca tcctaccact tggaggaaag agatttccac
    12781 attcctcaag tcaagtgcta tgagttaaca tttgaaggaa gcaaggaagg aaaggtctat
    12841 gcacgcattg ttcttccaaa gagtgaggag aaggttccac taatcttcca ttttcatggt
    12901 tatatgggac gtggctggga ctgggccgac atgctgggct tcaccgtagc tggttacggt
    12961 gttgtttcca tggatgtgcg gggccagtca ggttactcac aagacggctt gcgttctcct
    13021 ttaggaaata ccgtgaaggg gcatattatc cgtggtgcta tggaaggtcg ggaccacctc
    13081 ttttataagg atgtttatct ggatatttac cagttggtcg aaattgttgc tagtctgtct
    13141 caggttgatg agaagcgtct ttctagctat ggtgcctcac aaggaggggc tctagctcta
    13201 gttgcagcag cgctcaatcc tcgaattcag aaaacagttg ccatttatcc cttcttgtca
    13261 gacttcagac gggtgattga gattggtaat actagcgagg cttacgacga acttttccgt
    13321 tatttcaagt ttcacgaccc cttccatgaa acagaggagg aaatcatggc gacccttgcc
    13381 tatatcgatg tcaaaaatct tgcccatcgt atccaaggtg aggttaagat gattacgggc
    13441 ttggacgacg atgtttgcta tcccattacc cagtttgcga tttataatcg tctgacctgc
    13501 gataaaacct atcgtatcat gcctgagtat gctcacgaag ccatgaatgt atttgtcaat
    13561 gaccaagtct acaactggct ctgtggaagt gagattcctt ttaaatatct aaaataagga
    13621 gtcgactcta agcacaaaat cttaaaaatt acaaacacgc atagtatcag gggattaaaa
    13681 aaacttgata ctatgcgttt tatcatggaa atatagtaaa atgaaacaag aacaggacaa
    13741 atcgatcagg acagtcaaat cgatttctaa caatgtttta gaagtagatg tgtactattc
    13801 tagtttcaat ctattatatt tatagaattt tttgttgcta gatttgtcaa attgcttaaa
    13861 ataatttttt tcagaaagca aaagccgata cctatcgagt agggtagttc ttgctatcgt
    13921 caggcttgtc tgtaggtgtt aacacttttc aaaaatctct tcaaacaacg tcagctttgc
    13981 cttgccgtat atatgttact gacttcgtca gttctatctg ccacctcaaa ac
//
LOCUS       DAVLXH010000052        13289 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00028199
            SAMN33607166-rid17955573.denovo.052, whole genome shotgun sequence.
ACCESSION   DAVLXH010000052 DAVLXH010000000
VERSION     DAVLXH010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607166
            Sequence Read Archive: SRR23725544
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13289)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13289)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721421.1
            Genome Coverage       :: 115x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:42:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,210
            CDSs (total)                      :: 2,161
            Genes (coding)                    :: 2,023
            CDSs (with protein)               :: 2,023
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 73 of 138
            Pseudo Genes (incomplete)         :: 60 of 138
            Pseudo Genes (internal stop)      :: 40 of 138
            Pseudo Genes (multiple problems)  :: 31 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13289
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607166-rid17955573.denovo.052"
                     /strain="AUSMDU00028199"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1349"
     gene            complement(250..1416)
                     /locus_tag="VYO11_001724"
     CDS             complement(250..1416)
                     /locus_tag="VYO11_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001108652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HEV1596248.1"
                     /translation="MNYLVISPYYPQNFQQFTIELANKGITVLGIGQESYEQLDEPLR
                     NSLTEYFRVDNLENIDEVKRAVAFLFYKHGPIGRIESHNEYWLELDATLREQFNVFGA
                     KPEDLKKTKYKSEMKKLFKKAGVPVVPGAVIKTEADVDQAVKEIGLPMIAKPDNGVGA
                     AATFKLETEDDINHFKQEWDHSTLYFFEKFVTSSEICTFDGLVDKDGKIVFSTTFDYA
                     YTPLDLMIYKMDNSYYVLKDMDPKLRKYGEAIVKEFGMKERFFHIEFFREGDDYITIE
                     YNNRPAGGFTIDVYNFAHSLDLYRGYAAIVAGEEFPASDFETQYCLATSRRANAHYVY
                     SEEDLLAKYSQQFKVKKVMPAAFAELQGDYLYMLTTPSRQEMEQMIADFGQRQE"
     gene            complement(1429..2168)
                     /locus_tag="VYO11_001725"
                     /pseudo
     CDS             complement(1429..2168)
                     /locus_tag="VYO11_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000546805.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
     gene            complement(2190..3014)
                     /locus_tag="VYO11_001726"
     CDS             complement(2190..3014)
                     /locus_tag="VYO11_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001076725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEV1596249.1"
                     /translation="MNQSYFYLKMKEHKLKVPYTGKERRVRILLPKDYEKDTDRSYPV
                     VYFHDGQNVFYSKESFIGYSWKIIPAIKRNPDISHMIVVAIDNDGMGRMNEYAAWKFQ
                     ESPTPGQQFGGKGVEYAEFVMEVVKPFIDETYRTKADCQHTAMIGSSLGGNITQFIGL
                     EYQDQIGCLGVFSSANWLHQEAFNRYFECQKLSPDQRIFIYVGTEEADDTDKTLMDGN
                     IKQAYIDSSLCYYHDLIAGGVHLDNLVLKVQSGAIHSEIPWSENLPDCLRFFAEKW"
     gene            complement(3152..4366)
                     /gene="thiI"
                     /locus_tag="VYO11_001727"
     CDS             complement(3152..4366)
                     /gene="thiI"
                     /locus_tag="VYO11_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HEV1596250.1"
                     /translation="MQYSEIMIRYGELSTKGKNRMRFINKLRNNISDVLSIYAQVKVT
                     ADRDRAHAYLNGADYTAVAESLKQVFGIQNFSPVYKVEKSVEVLKSSVQEIMRDIYKE
                     GMTFKISSKRSDHNFELDSRELNQTLGGAVFEAIPNVQVQMKSPDINLQVEIREEAAY
                     LSYETIRGAGGLPVGTSGKGMLMLSGGIDSPVAGYLALKRGVDIEAVHFASPPYTSPG
                     ALKKAQDLTRKLTKFGGNIQFIEVPFTEIQEEIKAKAPEAYLMTLTRRFMMRITDRIR
                     EVRNGLVIINGESLGQVASQTLESMKAINAVTNTPIIRPVVTMDKLEIIDIAQEIDTF
                     DISIQPFEDCCTIFAPDRPKTNPKIKNAEQYEARMDVEGLVERAVAGIMITEITPQAE
                     KDEVDDLIDNLL"
     gene            complement(4375..5517)
                     /locus_tag="VYO11_001728"
     CDS             complement(4375..5517)
                     /locus_tag="VYO11_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEV1596251.1"
                     /translation="MIYFDNSATTKPYPEALETYMQVASKILGNPSSLHRLGDQATRI
                     LDASRQQIADLIGKKSDEIFFTSGGTEGDNWLIKGVAFEKAQFGKHIIVSAIEHPAVK
                     ESALWLKSQGFEVDFAPVDKKGLVDVEALAGLIRHDTILVSIMAVNNEIGSIQPIEAI
                     SEFLADKPTISFHVDAVQALAKIPTEKYLTERVDCATFSSHKFHGVRGVGFVYIKSGK
                     KITPLLTGGGQERDYRSTTENVAGIAATAKALRLSMEKLDIFRSKTGQMKAVIHQALL
                     NYPDIFVFSDEEDFAPHILTFGIKGVRGEVIVHAFEDYDIFISTTSACSSKAGKPAGT
                     LIAMGVDKDKAKSAVRLSLDLENDMSQVEQFLTKLKLIYNQTRKVR"
     gene            5655..6080
                     /locus_tag="VYO11_001729"
     CDS             5655..6080
                     /locus_tag="VYO11_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1596252.1"
                     /translation="MSNYRRTSKPKTEHIKKGFTVFQKTVATIASILGLITASITIMN
                     ALDNNKNIKKEPTTSQTTTIVKEIQKESPKENTSPTKETNTSQEKTQQEETPKSSVKE
                     EKKEDQKTATQDSSTPASSKPATENEKQPNTPTSENNTQ"
     gene            complement(6279..8504)
                     /locus_tag="VYO11_001730"
     CDS             complement(6279..8504)
                     /locus_tag="VYO11_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HEV1596253.1"
                     /translation="MLISLGIAILLIFAAFKLGAAGITLYNLIRLLVGSLAYLAIFGL
                     LIYLFFFKWIRKQEGLLSGFFTIFAGLLLIFEAYLVWKYGLDKSVLKGTMAQVVTDLT
                     GFRTTSFAGGGLIGVALYIPTAFLFSNIGTYFIGSILILVGSLLVSPWSVYDIAEFFS
                     RGFAKWWEGHERRKEERFVKQEEKARQKAEKEARLEQEETEKALLDLPPVDMETGEIL
                     TEEAVQNLPPIPEEKWVEPEIILPQAELKFPEQEDDSDDQDVQVDFSAKEALEYKLPS
                     LQLFAPDKPKDQSKEKKIVRENIKILEATFASFGIKVTVERAEIGPSVTKYEVKPAVG
                     VRVNRISNLSDDLALALAAKDVRIEAPIPGKSLIGIEVPNSDIATVSFRELWEQSQTK
                     AENFLEIPLGKAVNGTARAFDLSKMPHLLVAGSTGSGKSVAVNGIIASILMKARPDQV
                     KFMMVDPKMVELSVYNDIPHLLIPVVTNPRKASKALQKVVDEMENRYELFAKVGVRNI
                     AGFNAKVEEFNSQSEYKQIPLPFIVVIVDELADLMMVASKEVEDAIIRLGQKARAAGI
                     HMILATQRPSVDVISGLIKANVPSRVAFAVSSGTDSRTILDENGAEKLLGRGDMLFKP
                     IDENHPVRLQGSFISDDDVERIVNFIKTQADADYDESFDPGEVSENEGEFSDGDAGGD
                     PLFEEAKSLVIETQKASASMIQRRLSVGFNRATRLMEELEMAGVIGPAEGTKPRKVLQ
                     Q"
     gene            complement(8668..10620)
                     /locus_tag="VYO11_001731"
     CDS             complement(8668..10620)
                     /locus_tag="VYO11_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV1596254.1"
                     /translation="MKIQDLLRKDVMLLDLQATEKTAVIDEMIKNLTEHGYVTDFETF
                     KEGILAREALTSTGLGDGIAMPHSKNAAVKEATVLFAKSNKGVDYESLDGQATDLFFM
                     IAAPEGANDTHLAALAELSQYLMKDGFADKLRQATSADQVIELFDQASEKTEELVQAP
                     ANDSGDFIVAVTACTTGIAHTYMAQEALQKVAAEMGVGIKVETNGASGVGNQLTAEDI
                     RKAKAIIIAADKAVEMDRFDGKPLINRPVADGIRKTEELINLALSGDTEVYRAANGAK
                     AATASNEKQSLGGAFYKHLMSGVSQMLPFVIGGGIMIALAFLIDGALSVPNENLGNLG
                     SYHELASMFMKIGGAAFGLMLPVFAGYVAYSIAEKPGLVAGFVAGAIAKEGFAFGKIP
                     YAAGGEATSTLAGVSSGFLGALVGGFIAGALVLAIKKYVKVPRSLEGAKSILLLPLLG
                     TILTGFVMLAVNIPMAAINTAMNDFLGGLGGGSAVLLGIVLGGMMAVDMGGPVNKAAY
                     VFGTGTLAATVSSGGSVAMAAVMAGGMVPPLAIFVATLLFKDKFTKEERNSGLTNIIM
                     GLSFITEGAIPFGAADPARAIPSFILGSAVAGGLVGLTGIKLMAPHGGIFVIALTSNA
                     LLYLVSVLVGAIVSGVVYGYLRKPQA"
     gene            complement(10617..11528)
                     /gene="pfkB"
                     /locus_tag="VYO11_001732"
     CDS             complement(10617..11528)
                     /gene="pfkB"
                     /locus_tag="VYO11_001732"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015605104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HEV1596255.1"
                     /translation="MIYTVTLNPSIDYIVRLDQVKVGSVNRMDSDDKFAGGKGINVSR
                     VLKRLNIPNTATGFIGGFTGKFITDTLAEEEIETRFVQVAEDTRINVKIKADQETEIN
                     GTGPTVESVQLEELKAILSSLTAEDTVVFAGSSAKNLGNVIYKDLISLTRQTGAQVVC
                     DFEGQTLIDSLDYQPLLVKPNNHELGAIFGVKLESLDEIEKYARELLAKGAQNVIISM
                     AGDGALLVTSEGAYFAKPIKGTVKNSVGAGDSMVAGFTGEFVKSKDVVEAFKWGVACG
                     TATTFSDDLATAEFIKETYGKVEVEKR"
     gene            complement(11525..12265)
                     /locus_tag="VYO11_001733"
     CDS             complement(11525..12265)
                     /locus_tag="VYO11_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEV1596256.1"
                     /translation="MLKTERKQLILEELNQHHVVSLEKLVSLLETSESTVRRDLDELE
                     AENKLRRVHGGAELPHSLQEEETIQEKSVKNLQEKKLLAQKAASLIKEKDVIFIDAGT
                     TTAFLIHELVNKNVTVVTNSIHHAAQLVEKQIPTVMVGGNVKTATDASIGGVALNQIN
                     QLHFDRAFIGMNGVDDGYYTTPDMEEGAVKRAILENAKQTYVLVDSSKIGQTCFAKVA
                     PLKRAIVITSQGHELLQVIKEKTEVIEV"
     gene            12427..12514
                     /locus_tag="VYO11_001734"
     tRNA            12427..12514
                     /locus_tag="VYO11_001734"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:12461..12463,aa:Ser,seq:gga)
     gene            complement(12697..13044)
                     /gene="ssrA"
                     /locus_tag="VYO11_001735"
     tmRNA           complement(12697..13044)
                     /gene="ssrA"
                     /locus_tag="VYO11_001735"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
BASE COUNT         3906 a         2995 c         2545 g         3843 t
ORIGIN      
        1 tagactggtt tggtatcctg aaaactatat cgtataggtg tcgtcatgga tccttttagc
       61 tgatttaagg atacgcaaac acaatactat gactcaattg aaatattaaa atttaatttc
      121 tgaccaccta atcctgcttc aaatagttat cgaacaagtt ttatgatagc taccttgttg
      181 ggatgctctt attttttatc agacaaaaca aaaggattaa gggagttaat ttccttaatc
      241 cgatagttct tattcttgac gttgtccgaa atctgcaatc atctgctcca tttcttgtcg
      301 actcggagtg gtcagcatat acaggtaatc tccttgaagt tccgcgaagg cagctggcat
      361 gactttttta accttgaact gctggctata tttggcaagc aaatcctctt ctgaataaac
      421 atagtgagca tttgcacggc gagaagtagc caaacaatac tgagtttcaa agtctgacgc
      481 cgggaactcc tctcctgcga caatagctgc atagccacga taaaggtcca aggaatgagc
      541 aaagttataa acatcaatgg taaaaccacc tgcagggcgg ttattgtact cgatggtaat
      601 ataatcgtcc ccctcacgga agaactcaat atggaaaaac cgttctttca taccaaattc
      661 tttgacaatt gcttccccat acttgcgcag tttaggatcc atatccttga gcacataata
      721 agaattgtcc atcttataaa tcatgaggtc aagcggtgta taggcgtagt caaaggttgt
      781 tgagaagaca atctttccat ccttgtccac gagcccgtca aaggtacaga tttcgctgga
      841 agtgacaaat ttttcaaaga aataaagggt tgaatggtcc cattcttgct tgaagtgatt
      901 gatatcgtct tctgtctcaa gtttaaaggt tgcggctgct cccactccat tatcaggttt
      961 ggcaatcatt ggaagaccga tttctttcac tgcttgatca acatctgctt ccgtcttgat
     1021 aacagctcca ggtaccacag gaacacctgc ttttttgaaa agtttcttca tttcagactt
     1081 atatttcgtc tttttgagat cctctggttt ggcaccaaaa acattgaatt gttctctgag
     1141 tgttgcgtct agctcaagcc agtattcatt gtgagactcg atgcggccaa ttggaccatg
     1201 tttataaaag agaaaagcaa ctgcacgttt gacttcatct atgttctcaa gattatcaac
     1261 acgaaaatac tcggtcaagc tattgcgcaa gggctcatcc aattgctcgt aagactcttg
     1321 accaattccc aagactgtga tgcctttatt agctagttcg atggtaaact gttgaaagtt
     1381 ttgtggatag tagggagaaa taacaaggta attcataggt aactcctttt ataaatagag
     1441 attaccgagg aaataaggca tttgtttacg ccaccattcc cagtcatggg cgacatcatg
     1501 tccccattca gcaaaccagg ctggaatttg tttcttgtca aaggcttctt tgagcttgta
     1561 aaaggatggc aaaccatctt gttcccaggc tccaagcccc gtacacagca caatctctgc
     1621 ctgacggtaa cggtcaataa accagccgtc gttttggttc caaatataat ctactggcga
     1681 gttttggtaa atagcatcat cgttgtagta atcaccgaca aagaaacgtg cgtcgtaaac
     1741 accactgaga gcaatcactt tggtaaagac atctggatgc tggaggaaga aattgagtgc
     1801 atgataggct cccatagagc aacctgtcgt catcatgcca tcaaaccaac ctgtcttgtg
     1861 cttgataaaa gaatggcctc ctcaatcaca taacgttcgt aggcacggtg catttccgct
     1921 tggtcatgag catttttcca agtagccaac cagctctcac tatccacact agatagggta
     1981 aagaactgga caaggccttc ctcgataaag gaagcacagg catcaatcat gccaaaatca
     2041 tagtattcgt tgtgactacc acctgatgaa gcaaagacca caactggaat cccaccatgt
     2101 ccataacggt taaggtacat ttcacggtta agatgaccac tccagtggct aagatgttca
     2161 atatgcattt cgttttttcc tttcttaact taccattttt ctgcaaaaaa tctcagacaa
     2221 tctggtagat tttctgacca agggatttca ctatggatgg caccagactg aacttttagc
     2281 acaagattat ccagatgtac tccccctgct atcaaatcat ggtaatagca aagcgacgag
     2341 tcgatatagg cttgtttgat attgccatcc atcaaggtct tgtctgtatc atctgcttct
     2401 tctgttccta catagatgaa gatgcgctgg tcaggcgata gtttctggca ctcgaaatag
     2461 cggttaaagg cttcttggtg gagccagttt gcagatgaaa aaacgcccaa gcaaccaatt
     2521 tggtcttggt attccaaacc gataaactgg gtaatattgc ctcctagtga ggaaccaatc
     2581 atagccgtat gctggcagtc tgcttttgta cgataggtct catcgataaa aggcttgacc
     2641 acctccatga caaactcagc atactccaca cccttaccac caaactgctg ccctggggta
     2701 ggagattctt ggaacttcca agccgcatac tcattcatcc gccccatacc atcattgtca
     2761 atagcaacga caatcatgtg actgatatcc ggatttcgtt tgatagctgg gataatcttc
     2821 catgaatatc caatgaaaga ctctttgcta taaaaaacat tttgcccgtc atgaaagtat
     2881 acaacaggat aggaacggtc tgtatctttc tcataatctt taggaagaag aatacgtaca
     2941 cggcgctcct tacctgtata aggaaccttg agtttgtgtt ctttcatttt tagataaaag
     3001 taggattgat tcattgtcag aaaactctct atattcaaaa ttttatatca ttatatcatg
     3061 aaaatagaaa aaagttagtt ttttacctgt ttttagaaaa aaaaaactaa ctttttttac
     3121 tgattttcgc tattcttttg gattttctga attagagtag attatcaatc aagtcatcaa
     3181 cttcatcttt ttcggcttga ggtgtgattt cagtaatcat gattccagcc actgctcgct
     3241 caaccaagcc ttcaacatcc atacgcgctt cgtactgctc cgcattctta attttaggat
     3301 ttgtttttgg acgatctggt gcaaaaatgg tacaacagtc ttcaaacggt tggattgaaa
     3361 tgtcaaaggt atcgatttcc tgggcgatgt caatgatttc caacttgtcc atggtaacca
     3421 caggacgaat gatgggagtg ttggtaacag cattgatagc cttcatactt tcaagggttt
     3481 ggctggctac ttgacctaga ctttccccat tgatgataac caaaccattt cgtacctcac
     3541 gaatacggtc agtaatccgc atcataaagc gacgagttag agtcatcaaa taagcttctg
     3601 gcgctttggc tttgatttcc tcttgaatct ctgtgaaagg cacctcgata aactggatat
     3661 ttccgccaaa cttggtcaat ttacgtgtca agtcctgcgc tttcttgagg gcaccaggac
     3721 tagtatatgg tggactagca aagtgaactg cctcgatatc caccccacgc ttaagagcaa
     3781 gataacctgc tacaggtgag tcaatccctc ctgacaacat gagcatccct ttacctgaag
     3841 ttccaactgg caaaccacca gccccacgaa tggtttcata agaaagatag gctgcttctt
     3901 cacgaatctc cacctgaaga ttgatgtcag gacttttcat ttgaacttgc acatttggaa
     3961 tggcttcgaa tacagcccct ccaagtgttt ggttgagttc acgactatca agttcaaagt
     4021 tgtggtcgct acgcttgcta gaaatcttaa aggtcatacc ttccttgtag atgtcccgca
     4081 taatctcttg gacagaagac ttcaaaactt ctacagattt ttcaacctta taaacaggag
     4141 aaaagttttg aattccaaaa acttgtttga gagattctgc aactgctgtg taatcagctc
     4201 cattgaggta agcgtgggca cggtcgcgat ctgctgttac cttaacttgg gcatagatag
     4261 acaaaacgtc cgaaatatta ttacgaagtt tattgatgaa acgcatacgg tttttaccct
     4321 tggttgacaa ctctccgtag cgaatcataa tttctgaata ctgcatgaat gctcctatct
     4381 tacttttcta gtttgattgt aaatcaattt taacttggtc aaaaactgct cgacctgact
     4441 catatcattt tccaagtcta ggctaagacg cacagctgac ttggccttat ctttgtccac
     4501 tcccatggca atcaaggtac cggctggttt tcctgcctta gatgaacaag ctgaggttgt
     4561 tgagatgaaa atatcatagt cttcaaaggc gtgaacgatg acttcacctc gaacaccttt
     4621 gattccaaaa gtcagaatat gaggtgcaaa gtcttcctca tctgaaaaga caaaaatatc
     4681 cggatagttc agaagagctt ggtgaatcac tgccttcatc tgcccagtct tgctcctaaa
     4741 gatatctagc ttttccatag ataaacggag agccttggct gtcgctgcaa tccctgccac
     4801 attttcagtt gtcgaacgat aatctcgctc ctggccacca cctgtaagaa gaggtgtaat
     4861 cttcttgcca gatttgatat agacaaagcc aacaccacgg acaccatgaa atttatgact
     4921 cgagaaggtc gcgcaatcca cccgttctgt cagatacttt tcagtcggaa ttttggcaag
     4981 cgcctgaacc gcatcaacgt ggaaggaaat agtcggcttg tctgccaaga attctgaaat
     5041 agcctcaata ggttggatag agccgatttc attgttcaca gccatgatgg aaacgaggat
     5101 tgtatcatgc cgtatcaaac ctgctaacgc ctcaacatcg accaagcctt tcttatcaac
     5161 tggagcaaaa tccacttcaa atccttgact tttcaaccag agggctgact ctttgactgc
     5221 tggatgttca atggctgaaa caatgatgtg cttgccaaac tgagcttttt caaaggccac
     5281 acccttgata agccagttat ccccttctgt tccacccgag gtaaagaaga tttcatcgct
     5341 tttcttaccg attaaatctg caatctgttg gcgagaagca tctaagattc gtgttgcttg
     5401 gtctcccaaa cgatggagac tagatgggtt tcctaaaatt tttgaagcga cctgcatata
     5461 ggtttcaagg gcttcaggat aaggcttggt cgtcgctgaa ttatcaaagt aaatcatgtt
     5521 tctcacgctt tctaaaatca cttcctctat tgtatcatga aacggagctt gcgacaagaa
     5581 agggaaattt ctcttttttt aagatttttt taaagaaaca gagtataata aatcataatc
     5641 aaaggagaga atgtatgtct aactatcgta gaacttcaaa accaaaaaca gaacacatca
     5701 aaaaaggctt tacagtcttt caaaaaaccg ttgctacaat cgctagtatc cttggcttga
     5761 ttaccgcaag tatcacgatt atgaacgcct tggataataa caaaaatatt aaaaaagaac
     5821 ctacgacaag ccagacgaca accattgtca aagaaatcca aaaggaatcc cctaaggaaa
     5881 acaccagtcc aactaaagag actaacacta gtcaagaaaa aacacagcaa gaggaaacac
     5941 caaaatctag cgtcaaggaa gagaaaaaag aagatcagaa aacagcaact caggactctt
     6001 ctactcctgc ttcaagtaaa cctgctactg aaaacgaaaa acagcccaat actccaactt
     6061 cagaaaataa tactcaatga aaatcaaaga gcaaactagg aagctagccg caggttgctc
     6121 aaaacactgt tttgaggttg tggatagaac tgacagagtc agtatcatat acctacgaca
     6181 aggcgaagct gacgtggttt gaagagattt gcgaagagta taaaagtaat caataaccag
     6241 taaaatagct ccttccaacc ttggaaagaa gctatttttt attgctgcaa tacttttctt
     6301 ggcttggtac cttcagctgg accaatgaca cctgccatct caagctcttc catgagacgg
     6361 gtcgcacggt taaatccaac tgacaaacga cgctgaatca tggatgcact ggctttctgt
     6421 gtttcgataa ccaaagactt agcttcttca aaaagcggat caccaccagc atctccatcc
     6481 gaaaattctc cttcattttc agaaacctca cctggatcaa aactctcatc gtagtctgca
     6541 tctgcctgag tcttgatgaa gttcacaatg cgctcaacat cgtcatccga gataaaggag
     6601 ccttggagac gaactggatg attttcatca atcggtttaa agagcatgtc tcctcgacca
     6661 agaagttttt ctgctccatt ttcatccaaa atcgtacggg agtctgttcc tgatgaaacc
     6721 gcaaatgcta cacgagatgg aacattggcc ttaatcaaac cagagatgac atcaacagat
     6781 gggcgctgag ttgcaagaat catgtggata cctgcagcac gcgccttctg cccaagacgg
     6841 atgatagcat cttccacttc cttgctggcc accatcatga ggtcagccaa ctcatccaca
     6901 atcacgacaa tgaatggtag cggaatttgc ttgtactcag actgggaatt gaactcttct
     6961 accttggcat taaaacctgc aatattccga actcccacct tggcaaagag ttcataacgg
     7021 ttttccattt catccacaac cttttgcaga gccttgctgg ctttgcgtgg attggtcacg
     7081 actggaatca agaggtgggg aatatcattg taaacagata actcaaccat cttgggatcg
     7141 accatcataa atttaacttg atctggtctc gccttcatga gaatgctagc aataatgccg
     7201 ttaactgcta ctgacttccc tgaacccgtt gaacctgcaa ctagcaagtg gggcatttta
     7261 gaaaggtcaa aagctcttgc ggttccatta acagccttcc ctaaaggaat ttccaagaaa
     7321 ttttctgctt tcgtttgcga ttgttcccat agttctcgga aagatacagt ggcaatatcg
     7381 gagttgggca cttcaattcc gattagggat ttcccaggga ttggtgcttc aatccggaca
     7441 tccttagcag ccaaggctag agcgaggtca tctgatagat tggaaatgcg gttgaccctt
     7501 acaccaacag ccggcttgac ttcatacttg gtcactgatg gcccaatttc ggcccgttca
     7561 actgttacct taataccaaa gctagcaaag gttgcttcta agattttgat attttctctg
     7621 acaattttct tctctttaga ctgatctttt ggtttatctg gtgcaaagag ttgtaagctt
     7681 ggaagtttgt attcaagggc ttctttggct gaaaaatcga cctgaacatc ttggtcatct
     7741 gagtcatctt cctgttcagg gaatttaagt tcagcttgag gcaggatgat ttctggttcc
     7801 acccactttt cttctggaat aggtggaaga ttttgaacag cttcctctgt cagaatttca
     7861 cccgtttcca tatcaacagg aggcaaatcg agtaaggctt tttcagtctc ttcttgttct
     7921 aatctagcct ctttctcagc cttttggcga gctttttctt cttgtttgac aaagcgttcc
     7981 tcttttcgac gctcgtgccc ttcccaccat ttggcaaagc ctctactgaa aaattcagca
     8041 atatcgtaaa cagaccaagg gctgactagg agagaaccca ctaaaatcaa gatagaacca
     8101 ataaagtaag ttccgatatt tgaaaagaga aaggctgttg gaatataaag agcgaccccg
     8161 atcaagcccc ctccagcaaa actagtcgtt cgaaaaccag tcagatctgt cacaacctga
     8221 gccatggtcc cttttagaac ggacttgtcc aaaccatatt tccaaaccaa gtaggcctca
     8281 aaaatcaaga gtaagccagc aaatatggtg aaaaagccag ataagagtcc ttcctgtttt
     8341 cgtatccact tgaaaaagaa gagatagatt aataggccga atatcgccag ataagctagg
     8401 ctacccacta gcaagcgaat taaattataa agggttatac ctgcagcccc taatttgaag
     8461 gctgcgaaaa tcaataaaat cgcaattcct aacgaaatca acattcgttg aatcgcttct
     8521 tttctttcca gttctgcttt agacggtctc cgtcttgttg tacttgtatt cttgtttgcc
     8581 attcttctat tataccatat ttcacaggca tttcgggaag agaaaaagac tgcaccaaac
     8641 ggtccaatct tttcattttt ctatttttta tgcttgtggt ttgcgtaggt aaccataaac
     8701 cacaccactt acgattgctc ctaccaagac agaaacgagg taaaggagag catttgaagt
     8761 aagggcgata acgaagattc ctccgtgtgg cgccatgagt ttgataccag taagaccaac
     8821 gagtccacct gctactgctg aaccaaggat gaagcttgga atcgcacgag ctgggtcagc
     8881 ggcaccaaat ggaatcgctc cctcagtgat aaatgacaag cccatgatga tgtttgtcaa
     8941 accagagtta cgttcttcct tagtaaattt atctttgaaa agaagagttg cgacaaagat
     9001 tgcaagtggt ggcaccattc ctccagccat aactgctgcc atggctacag aaccacctga
     9061 agaaacagtt gctgcaagcg tacctgtacc aaaaacataa gctgctttat taactggtcc
     9121 acccatgtca acagccatca ttccaccaag gacgatacca agaaggacag ctgaacctcc
     9181 tccaagaccg cctaggaagt cattcatagc agtgttgatt gcagccattg ggatatttac
     9241 agctagcata acaaatcctg tcaagattgt tccaagaagt ggcaatagaa ggattgattt
     9301 agcaccttcg agtgaacgag gaactttaac gtatttcttg atggcaagaa ccaaggcacc
     9361 tgcgataaat ccaccaacaa gggcacctag gaaaccagat gagacacctg caagagttga
     9421 agttgcttca ccacctgcgg cataaggaat tttaccaaag gcaaaacctt ctttggcaat
     9481 agcaccagcc acgaaacctg ctaccaaacc tggtttttca gcaatagagt aggcaacata
     9541 acccgcaaag actggaagca tcaaaccaaa ggcagctcca ccaattttca tgaacataga
     9601 agctaactca tggtaagaac caagattgcc aaggttttca tttggaacac tcaaagcacc
     9661 gtcaatcaag aaggcaaggg caatcatgat accaccaccg ataacgaatg gtaacatttg
     9721 agatacacca ctcatcaagt gtttgtagaa ggcaccacca aggctttgtt tttcgttaga
     9781 ggctgttgca gcttttgcac cattagcggc acggtagact tcagtatctc ctgaaagagc
     9841 caagttaatt agctcttctg tcttacggat accgtcagca actggacgat tgatcaatgg
     9901 ttttccatca aatcgatcca tttcaacggc cttgtctgct gcaatgataa tagctttagc
     9961 cttacggata tcttctgcag ttagttgatt tccaacaccg ctagcaccgt tggtttcgac
    10021 cttgatacca acccccattt cagcagctac tttttgaagg gcttcttggg ccatgtaagt
    10081 gtgggcaata cctgttgtac aagctgtaac agctacgata aagtcaccag agtcattagc
    10141 aggtgcttga acaagttcct cagttttttc tgaagcttgg tcaaaaagtt cgataacttg
    10201 gtctgcagat gttgcttgac gaagtttgtc tgcaaaaccg tctttcatca agtattgaga
    10261 caattctgcc aaggctgcca agtgagtatc attggcacct tctggagctg caatcatgaa
    10321 gaagaggtca gttgcttgtc catccaagct ctcgtagtca acacccttat ttgacttagc
    10381 aaatagaact gtcgcttctt tgacagcagc gtttttgctg tgaggcattg cgattccatc
    10441 acccaaacca gtagaagtca aagcttcacg cgccaaaatt ccttctttaa atgtttcaaa
    10501 atctgttaca taaccgtgct ctgtcaaatt tttaatcatc tcgtcgatga cagctgtttt
    10561 ttcagttgcc tgcaaatcca gcaacatgac atcttttctc aataaatctt gaattttcat
    10621 cgtttttcta cctcaacttt tccatatgtt tctttaataa attccgccgt tgccaagtca
    10681 tctgagaagg tagttgccgt tccgcaagcc actccccatt tgaaggcttc tactacgtct
    10741 tttgatttga caaattcacc tgtgaatcca gcaaccatag aatcaccagc tccaactgaa
    10801 tttttgactg ttcctttgat tggtttagcg aagtaagctc cctcagatgt gacaagaagg
    10861 gcaccatcac cagccataga gataataaca ttttgagcac ccttagccag taactcacga
    10921 gcgtatttct caatttcatc taaactttcg agtttaaccc caaaaatcgc tccaagttca
    10981 tgattgtttg gttttacaag aagaggctgg tagtccaaac tatcaattaa agtctgtcct
    11041 tcaaagtcac agaccacttg cgcaccagtc tggcgcgtca aggaaatcaa atccttatag
    11101 ataacattgc ctagattttt agcacttgaa cctgcaaaga caactgtatc ttctgctgtc
    11161 agactagata aaatagcttt caattcttct agctgaaccg attcaacagt tggacccgtt
    11221 ccgttgattt ctgtttcttg gtctgctttg attttaacat tgatacgagt atcttctgcc
    11281 acctggacaa aacgtgtctc gatttcttcc tctgctaaag tatctgtgat aaatttacca
    11341 gtaaagccac cgataaatcc cgtcgctgta tttggtatat tcaaacgttt caagacacgg
    11401 ctgacattga ttcctttccc accagcaaac ttatcatcac tgtccatacg atttacacta
    11461 ccaactttga cttggtccaa acgaacgata tagtcaatgg atggattgag tgtgactgta
    11521 taaatcatac ttctattacc tccgttttct ccttaataac ctgcaagagc tcatgccctt
    11581 gactagtgat aacgatagcg cgtttgagtg gtgctacctt ggcaaagcaa gtttgtccaa
    11641 tttttgacga atccaccaag acgtaggtct gcttggcatt ctccaaaata gctcttttca
    11701 cagctccctc ctccatatca ggagtcgtat aatagccatc gtcaacacca ttcattccga
    11761 taaaggcacg gtcaaagtgc aattggttaa tctggttaag agcaacgccc ccgatactag
    11821 catctgtcgc cgtcttgacg tttcctccaa ccatgacagt tggaatctgc ttttcaacca
    11881 actgagcggc atggtgaatg gagttggtca caactgtaac attcttattg accaattcat
    11941 gaatcaaaaa agcagttgtt gttccagcat cgataaagat gacatctttt tctttaatga
    12001 gagaggctgc tttctgagcc agcaacttct tttcttgaag gtttttgaca gatttttctt
    12061 gaatggtttc ttcttcctgt aaggagtggg ggagttctgc tccaccatgc acacgacgaa
    12121 gcttgttttc cgcttccaac tcatccaagt ctcttcgaac cgttgattct gacgtttcta
    12181 gcaaactaac taatttttct agagaaacta catgatgctg atttaactcc tctaaaatta
    12241 gttgtttacg ttctgttttt aacactgaat cacctcctgt tatcgtttac actattcatt
    12301 ctatcatact ttctttcgaa gtcaagcatt ttttatcatt ttctttcaaa atctatcatt
    12361 tttcttattt ctagaatttt tattgcaaga taagagcctt tatggtagac tatttgagta
    12421 agtattggaa gattactcaa gaggcttaag aggccgtgtt ggaaacgcgg taggcgtgta
    12481 atagcgtgcg tgggttcgaa tcccatgtct tccgtcgaaa aaagattatt tttaggatgc
    12541 gacaaatgtt gtatcctttt ttctatcctt tttttaaaat agggtctgtt tgtgactccc
    12601 tttttagcaa aagaatgcaa aggaatacca aagataaaaa taaaaaacgt tgatttaaca
    12661 acgttttacc aaggaatgca aaagaatgca aaggaataat ggagccggtg ggagtcgaac
    12721 ccacgtccaa acacctgcca acatatttgt ctacaaccat aggttatgta ttattttaac
    12781 agcccctcga cacataactc aagtctagaa actgcgagtc tatcaatctc ttatcaagcc
    12841 gctagacaag gcttaatcgt atctcgctaa taataagacc tgtcattgaa cacgagcaat
    12901 ccaaatcggg tcacgcctgc tggtttttag gcagctagag cgtaagaagt gttatttttt
    12961 gcagttatat ttaactgagc gtttacgtcg ccacacgagt cgcaaaatat gcctcataat
    13021 gcctgtcgaa tccgtaacga ccccaaaaga caataaaacc attatacctt atctaactca
    13081 aaaatgcaaa aagaaatcac atacctaaga tgaagctatc tgttttgaag aaattcacga
    13141 agagaattat tctaaaatac tttcagatga gaattttcgt actctcttta tttcaattca
    13201 tttgagttta aaaactataa aatcaatcct tatattattc ggtctacttt tcacttattg
    13261 caccaaaata tagtaaaatg aaataagaa
//
LOCUS       DAVLXH010000053        12817 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00028199
            SAMN33607166-rid17955573.denovo.053, whole genome shotgun sequence.
ACCESSION   DAVLXH010000053 DAVLXH010000000
VERSION     DAVLXH010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607166
            Sequence Read Archive: SRR23725544
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12817)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12817)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721421.1
            Genome Coverage       :: 115x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:42:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,210
            CDSs (total)                      :: 2,161
            Genes (coding)                    :: 2,023
            CDSs (with protein)               :: 2,023
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 73 of 138
            Pseudo Genes (incomplete)         :: 60 of 138
            Pseudo Genes (internal stop)      :: 40 of 138
            Pseudo Genes (multiple problems)  :: 31 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12817
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607166-rid17955573.denovo.053"
                     /strain="AUSMDU00028199"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1349"
     gene            <1..1076
                     /gene="dnaN"
                     /locus_tag="VYO11_001736"
     CDS             <1..1076
                     /gene="dnaN"
                     /locus_tag="VYO11_001736"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HEV1596257.1"
                     /translation="ISSKNAIPILSTVKIDVTNEGITLIGSNGQISIENFISQKNEDA
                     GLLITSLGSILLEASFFINVVSSLPDVTLDFKEIEQNQIVLTSGKSEITLKGKDSEQY
                     PRIQEISASTPLILETKLLKKIINETAFAASTQESRPILTGVHFVLSQHKELKTVATD
                     SHRLSQKKLTLEKNSDDFDVVIPSRSLREFSAVFTDDIETVEIFFANNQILFRSENIS
                     FYTRLLEGNYPDTDRLIPTDFNTTITFNVVNLRQSMERARLLSSATQNGTVKLEIKDG
                     VVSAHVHSPEVGKVNEEIDTDQVTGEDLTISFNPTYLIDSLKALNSEKVTISFISAVR
                     PFTLVPADTDEDFMQLITPVRTN"
     gene            1141..1335
                     /locus_tag="VYO11_001737"
     CDS             1141..1335
                     /locus_tag="VYO11_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 family protein"
                     /protein_id="HEV1596258.1"
                     /translation="MYQVGNFVEMKKSHACTIKSTGKKANRWEITRVGADIKIKCSNC
                     EHVVMMGRYDFERKMNKIID"
     gene            1419..2534
                     /gene="ychF"
                     /locus_tag="VYO11_001738"
     CDS             1419..2534
                     /gene="ychF"
                     /locus_tag="VYO11_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HEV1596259.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDERLQKLTEMITPKKTVPTTFEFTDIAGIVKGASKGEGLGNKFLANIREVDAIVH
                     VVRAFDDENVMREQGREDAFVDPLADIDTINLELILADLESVNKRYARVEKMARTQKD
                     KESVAEFNVLQKIKPVLEDGKSARTIEFTDEEQKVVKGLFLLTTKPVLYVANVDEDVV
                     SEPDSIDYVKQIREFAATENAEVVVISARAEEEISELDDEDKKEFLEAIGLTESGVDK
                     LTRAAYHLLGLGTYFTAGEKEVRAWTFKRGMKAPQAAGIIHSDFEKGFIRAVTMSYED
                     LVKYGSEKAVKEAGRLREEGKEYIVQDGDIMEFRFNV"
     gene            2605..3174
                     /locus_tag="VYO11_001739"
     CDS             2605..3174
                     /locus_tag="VYO11_001739"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HEV1596260.1"
                     /translation="MTKLLVGLGNPGDKYFETKHNVGFMLIDQLAKKQNVTFTHDKIF
                     QADLASFFLNGEKIYLVKPTTFMNESGKAVHALLTYYGLDIDDLLIIYDDLDMEVGKI
                     RLRAKGSAGGHNGIKSIIQHIGTQVFNRVKIGIGRPKNGMSVVHHVLSKFDRDEYIGI
                     LQSVDKVDDSVNYYLQEKNFEKTMQRYNG"
     gene            3175..6684
                     /gene="mfd"
                     /locus_tag="VYO11_001740"
     CDS             3175..6684
                     /gene="mfd"
                     /locus_tag="VYO11_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000258090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HEV1596261.1"
                     /translation="MVTLLDLFSENDQIKKWHQNLTDKKRQLILGLSTSTKALAIASS
                     LEKEDRIVLLMSTYGEAEGLVSDLISILGEELVYPFLVDDAPMVEFLMSSQEKIISRV
                     EALRFLTDSSKKGILVCNIAASRLILPSPNAFKDSIVKISVGEEYDQHAFIHQLKENG
                     YRKVTQVQTQGEFSLRGDILDIFEISQLEPCRIEFFGDEIDGIRSFEVETQLSKENKT
                     ELTIFPASDMLLREKDYQRGQSALEKQISKTLSPILKSYLEEILSSFHQKQSHADSRK
                     FLSLCYDKTWTVFDYIEKDTPIFFDDYQKLMNQYEVFERELAQYFTEELQNSKAFSDM
                     QYFSDIEQIYKKQSPVTFFSNLQKGLGNLKFDKIYQFNQYPMQEFFNQFSFLKEEIER
                     YKKMDYTIILQSSNLMGSKTLEDMLEEYQIKLDSRDKTNICKESVNLIEGNLRHGFHF
                     VDEKILLITEHEIFQKKLKRRFRRQHVSNAERLKDYNELEKGDYVVHHIHGIGQYLGI
                     ETIEIKGIHRDYVSVQYQNGDQISIPVEQIHLLSKYISSDGKAPKLNKLNDGHFKKAK
                     QKVKNQVEDIADDLIKLYSERSQLKGFAFSADDDDQDAFDDAFPYVETDDQLRSIEEI
                     KRDMQASQPMDRLLVGDVGFGKTEVAMRAAFKAVNDHKQVVILVPTTVLAQQHYTNFK
                     ERFQNFAVNIDVLSRFRSKKEQTATLEKLKNGQVDILIGTHRVLSKDVVFADLGLMII
                     DEEQRFGVKHKETLKELKKQVDVLTLTATPIPRTLHMSMLGIRDLSVIETPPTNRYPV
                     QTYVLEKNDSVIRDAVLREMERGGQVYYLYNKVDTIVQKVSELQELIPEASIGYVHGR
                     MSEVQLENTLLDFIEGQYDILVTTTIIETGVDIPNANTLFIENADHMGLSTLYQLRGR
                     VGRSNRIAYAYLMYRPEKSISEVSEKRLEAIKGFTELGSGFKIAMRDLSIRGAGNLLG
                     KSQSGFIDSVGFELYSQLLEEAIAKRNGNANANTRTKGNAELILQIDAYLPDTYISDQ
                     RHKIEIYKKIRQIDNRVNYEELQEELIDRFGEYPDVVAYLLEIGLVKSYLDKVFVQRV
                     ERKDNKITIQFEKVTQRLFLAQDYFKALSVTNLKAGIAENKGLMELVFDVQNKKDYEI
                     LEGLLIFGESLLEIKESKEENSI"
     gene            6742..7008
                     /locus_tag="VYO11_001741"
     CDS             6742..7008
                     /locus_tag="VYO11_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HEV1596262.1"
                     /translation="MRLDKYLKVSRIIKRRTVAKEVADKGRIKVNGILAKSSTDLKVN
                     DQVEIRFGNKLLLVKVLEMKDSTKKEDAAGMYEIISETRVEENV"
     gene            7001..7369
                     /locus_tag="VYO11_001742"
     CDS             7001..7369
                     /locus_tag="VYO11_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HEV1596263.1"
                     /translation="MSKNIVQLNNSFIQNEYQRRRYLMKERQKRNRFMGGVLILIMLL
                     FILPTFNLAQSYQQLLQRRQQLADLQTQYQTLSDEKDKETAFATKLKDEDYAAKYTRA
                     KYYYSKSREKVYTIPDLLQR"
     gene            7489..8757
                     /locus_tag="VYO11_001743"
     CDS             7489..8757
                     /locus_tag="VYO11_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A beta-lactamase-related serine hydrolase"
                     /protein_id="HEV1596264.1"
                     /translation="MRKFLIILLLPSFLTISKVVSTEKEVVYTSKEIYYLSQSDFGIY
                     FREKLSSPMVYGEVPVYANEDLVVESGKLTPKTSFQITEWRLNKQGIPVFKLSNHQFI
                     AADKRFLYDQSEVTPTIKKVWLESDFKLYNSPYDLKEVKSSLSAYSQVSIDKTMFVEG
                     REFLHIDQAGWVAKESTSEEDNRMSKVQEMLSEKYQKDSFSIYVKQLTTGKEAGINQD
                     EKMYAASVLKLSYLYYTQEKINEGLYQLDTTVKYVSAVNDFPGSYKPEGSGSLPKKED
                     NKEYSLKDLITKVSKESDNVAHNLLGYYISNQSDATFKSKMSAIMGDDWDPKEKLISS
                     KMAGKFMEAIYNQNGFVLESLTKTDFDSQRIAKGVSVKVAHKIGDADEFKHDTGVVYA
                     DSPFILSIFTKNSDYDTISKIAKDVYEVLK"
     gene            8754..10031
                     /gene="tilS"
                     /locus_tag="VYO11_001744"
     CDS             8754..10031
                     /gene="tilS"
                     /locus_tag="VYO11_001744"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HEV1596265.1"
                     /translation="MREPDFLNHFLKKGYFKKHAKAVLALSGGLDSMFLFKVLSTYQK
                     ELEIELILAHVNHKQRIESDWEEKELRKLAAEAELPIYISNFSGEFSEARARNFRYDF
                     FQEVMKKTGATALVTAHHADDQVETIFMRLIRGTRLRYLSGIKEKQVVGEIEIIRPFL
                     HFQKKDFPSIFHFEDTSNQENHYFRNRIRNSYLPKLEKENPRFRDAILGIGNEILDYD
                     LAIAELSNNINVEDLQQLFSYSESTQRVLLQTYLNRFPDLNLTKTQFAEVQQILKSKS
                     QYRHPIKNGYELIKEYQQFQICKISPQADEKEDELVLHYQNQVAYQGYLFSFGLPLEG
                     ELIQQIPVSRETSIHIRHRKTGDVLIQNGHRKKLRRLFIDLKIPMEKRNSALIIEQFG
                     EIVSILGIATNNLSKKTKNDIMNTVLYIEKIDR"
     gene            10035..10577
                     /gene="hpt"
                     /locus_tag="VYO11_001745"
     CDS             10035..10577
                     /gene="hpt"
                     /locus_tag="VYO11_001745"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HEV1596266.1"
                     /translation="MLENDIKKVLVSHDEITEAAKKLGAQLTKDYAGKNPILVGILKG
                     SIPFMAELVKHIDTHIEMDFMMVSSYHGGTASSGVINIKQDVTQDIKGRHVLFVEDII
                     DTGQTLKNLRDMFKAREAASVKIATLLDKPEGRVVEIEADYTCFTIPNEFVVGYGLDY
                     KENYRNLPYIGVLKEEVYSN"
     gene            10593..12551
                     /gene="ftsH"
                     /locus_tag="VYO11_001746"
     CDS             10593..12551
                     /gene="ftsH"
                     /locus_tag="VYO11_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HEV1596267.1"
                     /translation="MKKQNNGLIKNPFLWLLFIFFLVTGFQYFYSGNNSGGSQQINYT
                     ELVQEITDGNVKELTYQPNGSVIEVSGVYKNPKTSKEGTGIQFFTPSVTKVEKFTSTI
                     LPADTTVSELQKLATDHKAEVTVKHESSSGIWINLLVSIVPFGILFFFLFSMMGNMGG
                     GNGRNPMSFGRSKAKAANKEDIKVRFSDVAGAEEEKQELVEVVEFLKDPKRFTKLGAR
                     IPAGVLLEGPPGTGKTLLAKAVAGEAGVPFFSISGSDFVEMFVGVGASRVRSLFEDAK
                     KAAPAIIFIDEIDAVGRQRGVGLGGGNDEREQTLNQLLIEMDGFEGNEGIIVIAATNR
                     SDVLDPALLRPGRFDRKVLVGRPDVKGREAILKVHAKNKPLAEDVDLKLVAQQTPGFV
                     GADLENVLNEAALVAARRNKSIIDASDIDEAEDRVIAGPSKKDKTVSQKERELVAYHE
                     AGHTIVGLVLSNARVVHKVTIVPRGRAGGYMIALPKEDQMLLSKEDMKEQLAGLMGGR
                     VAEEIIFNVQTTGASNDFEQATQMARAMVTEYGMSEKLGPVQYEGNHAMLGAQSPQKS
                     ISEQTAYEIDEEVRSLLNEARNKAAEIIQSNRETHKLIAEALLKYETLDSTQIKALYE
                     TGKMPEAVEEESHALSYDEVKSKMNDEK"
BASE COUNT         4408 a         1915 c         2628 g         3866 t
ORIGIN      
        1 ctattagttc taaaaatgcc attcctattt tatcaacagt aaaaattgac gtgaccaatg
       61 aaggtattac tttaattggt tcaaatggtc aaatttcaat tgaaaatttt atttctcaaa
      121 aaaatgaaga tgctggtttg ttaattactt ctttaggttc gatccttctt gaagcttctt
      181 tctttatcaa tgtagtatct agtttacctg atgtaactct tgattttaaa gaaattgaac
      241 aaaatcaaat tgttttaacc agtggcaaat cagaaattac cctaaaagga aaagatagcg
      301 aacaatatcc acgaatccaa gaaatttcag caagcactcc tttaatactt gaaacaaaat
      361 tactcaagaa aattattaat gaaacagcct ttgctgcaag tacacaagag agtcgtccga
      421 ttttaacagg tgtccacttc gtattgagtc aacacaaaga gttaaaaaca gttgcaacag
      481 actctcatcg cctaagccag aaaaaattga ctcttgaaaa aaatagtgat gattttgatg
      541 tcgtaattcc tagccgttct ctacgcgaat tttcagcggt atttacagat gatatcgaaa
      601 ctgtagagat tttctttgcc aataaccaaa tcctctttag aagcgaaaat attagcttct
      661 atactcgtct cctagaagga aactatcctg atacagatcg cttgattcca acagacttta
      721 acactactat tacttttaat gtggtaaact tacgccagtc aatggagcgt gcccgtcttt
      781 tatcaagtgc gactcaaaat ggtactgtga aacttgaaat taaggatggg gttgttagcg
      841 cccatgttca ctctccagaa gttggtaaag taaacgaaga aatcgatact gatcaggtta
      901 ctggtgaaga tttgaccatt agtttcaacc caacttactt gattgattct cttaaagctt
      961 taaatagcga aaaggtgacc attagcttta tctcagctgt tcgtccattt actcttgtgc
     1021 cagcagatac tgacgaagac ttcatgcagc tcattacacc agttcgtaca aattaagtga
     1081 aagaggttga gcctggctcg cctcttttat gatataatcg aaaaagaaaa ggagagtagt
     1141 atgtatcaag ttggaaattt tgttgagatg aaaaaatcac acgcttgtac aatcaagtcg
     1201 actggtaaaa aggctaatcg ttgggaaatt acacgtgtag gagcagatat caaaataaaa
     1261 tgcagtaatt gtgagcatgt tgtcatgatg gggcgatatg attttgagcg aaaaatgaat
     1321 aaaattattg actgagaacc cttagttaga gggttagcac tttatccctt tttgtgttat
     1381 aatattaggg attgaaatga aaacggagaa tgagaaatat ggctttgaca gcaggtatcg
     1441 ttggtttgcc aaacgttggt aaatcaacac tatttaatgc aattacaaaa gcaggagcag
     1501 aggcagcaaa ctacccattt gcgactattg atccaaatgt tggaatggtg gaagttccag
     1561 atgaacgcct acaaaaacta actgaaatga taactcctaa aaagacagtt cccacaacat
     1621 ttgaatttac ggatattgca gggattgtaa aaggagcttc aaaaggagaa gggctaggga
     1681 ataaattctt ggccaatatt cgtgaagtag atgcgattgt tcacgtagtt cgtgcttttg
     1741 atgatgaaaa tgtgatgcgc gagcaaggac gtgaagacgc ctttgtagat ccacttgcag
     1801 atattgatac aattaatctg gaattaattc ttgctgactt agaatcagtg aacaaacgat
     1861 atgcgcgtgt agaaaagatg gcacgtacgc aaaaagataa agaatcagta gcagaattta
     1921 atgttcttca aaagattaaa ccagtcctag aagacgggaa atcagctcgt accattgaat
     1981 ttacagatga ggaacaaaag gttgtcaaag gtcttttcct tttgacgact aaaccagttc
     2041 tttatgtagc taatgtggac gaggatgtgg tttcagaacc tgactctatc gactatgtca
     2101 aacaaattcg tgaatttgca gcgacagaaa atgctgaagt agtcgttatt tctgcgcgtg
     2161 ctgaggaaga aatttctgaa ttggatgatg aagataaaaa agagtttctt gaagccattg
     2221 gtttgacaga atcaggtgta gataagttga cgcgtgcagc ttaccacttg cttggattgg
     2281 gaacttactt tacagctggt gaaaaagaag ttcgcgcttg gactttcaaa cgtggtatga
     2341 aggctcctca agcagctggt attatccact cagactttga aaaaggtttt attcgtgcag
     2401 taaccatgtc atatgaagat ctagtgaaat acggatctga aaaggccgta aaagaagctg
     2461 gacgcttgcg tgaagaagga aaagaatata tcgttcaaga tggcgatatc atggaattcc
     2521 gctttaatgt ctaaaaatta ataaatggtg tcaattaggt tggaaaaaaa ttccaaccct
     2581 tttggctttt gaaaggaaaa ataaatgacc aaattacttg taggcttggg aaatccaggg
     2641 gataaatatt ttgaaacaaa acacaatgtt ggttttatgt tgattgatca actagcgaag
     2701 aaacagaatg tcacttttac acacgataag atatttcaag ctgacctagc atcctttttc
     2761 ctaaatggag aaaaaattta tctggttaaa ccaacgacct ttatgaatga aagtggaaaa
     2821 gcagttcatg ctttattaac ttactatggt ttggatattg acgatttact tatcatttac
     2881 gatgatcttg acatggaagt tgggaaaatt cgtttaagag caaaaggctc agcaggtggt
     2941 cataatggta tcaagtctat tattcaacat ataggaactc aggtctttaa ccgtgttaag
     3001 attggaattg gaagacctaa aaatggtatg tcagttgttc atcatgtttt gagtaagttt
     3061 gacagggatg agtatatcgg tattttacag tctgttgaca aagttgacga ttctgtaaac
     3121 tactatttac aagagaaaaa ttttgagaaa acaatgcaga ggtataacgg ataaatggtg
     3181 accttattag atttattctc agaaaatgat cagattaaaa aatggcatca aaatttaaca
     3241 gataagaaaa gacaactaat acttggttta tcaacatcta ctaaggctct tgcaattgca
     3301 agcagtttag aaaaagaaga taggattgtg ttattgatgt caacttatgg agaagcagaa
     3361 ggacttgtta gtgatcttat atctatcttg ggtgaggaac tcgtctatcc atttttggta
     3421 gatgatgctc ctatggtgga gtttttgatg tcttcacagg aaaaaattat ttcacgggtt
     3481 gaagccttgc gttttttgac tgattcatct aagaaaggga ttttagtttg taatatcgca
     3541 gcaagtcgat tgattttacc gtctcccaat gcattcaaag atagtattgt aaaaatctca
     3601 gttggtgaag aatatgatca acacgcgttt atccatcagt taaaggaaaa tggctatcga
     3661 aaagttactc aagtacaaac tcagggcgaa tttagtcttc gaggagatat tttagatatt
     3721 tttgaaatat cccagttaga accttgtcga attgagtttt ttggtgatga aattgatggt
     3781 atcaggtcat ttgaagtaga aacacaatta tcgaaagaaa ataagacaga actcactatc
     3841 tttccagcta gtgatatgct tttgagagaa aaggattatc aacgaggaca gtcagcttta
     3901 gaaaaacaaa tttcaaaaac tttatcacct attttgaaat catacctaga agaaattctt
     3961 tcaagttttc accaaaaaca aagtcatgca gactctcgga agtttttatc tttgtgctat
     4021 gataagacat ggactgtctt tgattatatt gaaaaagata ctccaatatt ctttgatgat
     4081 tatcaaaaat tgatgaatca gtatgaagtc tttgaaagag aattagcgca gtactttaca
     4141 gaagaattac agaatagtaa agcattttct gatatgcagt atttttctga tattgaacaa
     4201 atctataaaa aacaaagtcc agtgaccttt ttttctaatc ttcaaaaggg tttaggaaat
     4261 ctcaaatttg acaaaattta tcaattcaat caatatccta tgcaggaatt tttcaatcag
     4321 ttttcttttc taaaagaaga aattgaacga tataaaaaaa tggattacac cattattctg
     4381 cagtctagca atttaatggg aagtaaaaca ttggaggata tgttagagga atatcagatt
     4441 aaattggatt ctagagataa gacaaatatc tgtaaagaat ctgtaaactt aatagagggt
     4501 aatctcagac atggttttca ttttgtagat gaaaagattt tattgataac tgaacatgag
     4561 atttttcaaa agaaattaaa gcgtcgtttt cgaagacaac atgtttcaaa tgcagagaga
     4621 ttaaaagatt acaatgaact tgaaaaaggg gactatgttg tccatcatat ccatgggatt
     4681 ggtcaatatc taggaattga aaccattgaa atcaagggaa ttcatcgtga ttatgtcagt
     4741 gtccaatacc aaaatggtga tcaaatttct attcccgtgg aacagattca tctactgtcc
     4801 aaatatattt caagtgatgg taaagctcca aaactcaata aattaaatga cggtcatttt
     4861 aaaaaggcca agcaaaaggt taagaaccag gtagaggata tagctgatga tttaatcaaa
     4921 ctctactctg aacgtagtca gttgaagggt tttgctttct cagctgatga tgatgatcaa
     4981 gatgcctttg atgatgcttt cccttatgtt gaaacggatg atcaacttcg tagtattgag
     5041 gaaatcaaga gggatatgca ggcttctcag ccaatggatc gacttttagt tggggatgtt
     5101 ggttttggaa agactgaagt tgctatgcgt gcagccttta aagcagtcaa tgatcacaaa
     5161 caggttgtca ttctagttcc gacgacggtt ttagcgcaac agcactatac gaattttaag
     5221 gaacgattcc aaaattttgc agttaatatt gatgtgttga gtcgctttag aagtaaaaaa
     5281 gagcagactg caacacttga aaaattgaaa aacggtcaag tcgatatttt gattggaaca
     5341 catcgtgttt tgtcaaaaga tgttgtgttt gctgatttgg gcttgatgat tattgatgag
     5401 gaacagcgat ttggtgtcaa gcataaggaa actttgaaag aactgaagaa acaagtggat
     5461 gtcctaacct tgaccgctac gccaatccct cgtaccctcc atatgtctat gctgggaatc
     5521 agagatttat ctgttattga aactccgccg actaatcgct atcctgttca gacctatgtt
     5581 ttggaaaaga atgatagtgt cattcgtgat gctgtcttgc gtgaaatgga gcgtggaggt
     5641 caagtttatt atctttacaa caaagttgac acaattgttc agaaggtttc agaattacag
     5701 gagttgattc cggaggcttc gattggatat gttcatggtc gaatgagtga agtccagttg
     5761 gaaaatactc tattagactt tattgaggga caatacgata tcttggtgac gactactatt
     5821 attgagacag gggtggacat tccaaatgct aatactttat ttattgaaaa tgcggaccat
     5881 atgggcttgt caaccttata tcagttaaga ggaagagtcg gtcgtagtaa tcgtattgct
     5941 tatgcttatc tcatgtatcg tccagaaaaa tcaatcagtg aagtctctga aaagagatta
     6001 gaagcgatta aaggatttac agaattgggc tctggcttta agattgcaat gcgagatctt
     6061 tcgattcgtg gagcaggaaa tcttttagga aaatcccagt ctggtttcat tgattctgtt
     6121 ggttttgaat tgtattcgca gttattagag gaagctattg ctaaacgaaa cggtaatgct
     6181 aacgctaaca caagaaccaa agggaatgct gagttgattt tgcaaattga tgcctatctt
     6241 cctgatactt atatttctga tcaacgacat aagattgaaa tttacaagaa aattcgtcaa
     6301 attgacaacc gtgtcaatta tgaagagtta caagaggagt tgatagaccg ttttggagaa
     6361 tacccagatg tagtagccta tctgttagag attggtttgg ttaaatcata cttggacaag
     6421 gtctttgttc aacgtgtgga aagaaaagat aataaaatta caattcaatt tgaaaaagtc
     6481 actcaacgac tgtttttagc tcaagattat tttaaagctt tatccgtaac gaacttaaaa
     6541 gcaggcatcg ctgagaataa gggattaatg gagcttgtat ttgatgtcca aaataagaaa
     6601 gattatgaaa ttttagaagg tttgctgatt tttggagaaa gtttattaga gataaaagag
     6661 tctaaggaag aaaattccat ttgatatttt tcttctataa aatagataaa aatggtacaa
     6721 taataaattg aggtaataag gatgagatta gataaatatt taaaagtatc gcgaattatc
     6781 aagcgtcgta cagtcgcaaa ggaagtagca gataaaggta gaatcaaggt taatggaatc
     6841 ttggccaaaa gttcaacgga cttgaaagtt aatgaccaag ttgaaattcg ctttggcaat
     6901 aagttgctgc ttgtaaaagt actagagatg aaagatagta caaaaaaaga agatgcagca
     6961 ggaatgtatg aaattatcag tgaaacacgg gtagaagaaa atgtctaaaa atattgtaca
     7021 attgaataat tcttttattc aaaatgaata ccaacgtcgt cgctacctga tgaaagaacg
     7081 acaaaaacgg aatcgtttta tgggaggggt attgattttg attatgctat tatttatctt
     7141 gccaactttt aatttagcgc agagttatca gcaattactc caaagacgtc agcaattagc
     7201 agacttgcaa actcagtatc aaactttgag tgatgaaaag gataaggaga cagcatttgc
     7261 taccaagttg aaagatgaag attatgctgc taaatataca cgagcgaagt actattattc
     7321 taagtcgagg gaaaaagttt atacgattcc tgacttgctt caaaggtgat aaaatggaaa
     7381 atttattaga cgtaatagag caatttttga gtttgtcaga tgaaaagctg gaagaattgg
     7441 ctgataaaaa tcaattattg cgtttacaag aagaaaagga aaggaagaat gcgtaaattc
     7501 ttaattattt tgttgctacc aagttttttg accatttcaa aagtcgttag cacagaaaaa
     7561 gaagtcgtct atacttcgaa agaaatttat tacctttcac aatctgactt tggtatttat
     7621 tttagagaaa aattaagttc tcccatggtt tatggagagg ttcctgttta tgcgaatgaa
     7681 gatttagtag tggaatctgg gaaattgact cccaaaacaa gttttcaaat aaccgagtgg
     7741 cgcttaaata aacaaggaat tccagtattt aagctatcaa atcatcaatt tatagctgcg
     7801 gacaaacgat ttttatatga tcaatcagag gtaactccaa caataaaaaa agtatggtta
     7861 gaatctgact ttaaactgta caatagtcct tatgatttaa aagaagtgaa atcatcctta
     7921 tcagcttatt cgcaagtatc aatcgacaag accatgtttg tagaaggaag agaatttcta
     7981 catattgatc aggctggatg ggtagctaaa gaatcaactt ctgaagaaga taatcggatg
     8041 agtaaagttc aagaaatgtt atctgaaaaa tatcagaaag attctttctc tatttatgtt
     8101 aagcaactga ctactggaaa agaagctggt atcaatcaag atgaaaagat gtatgcagcc
     8161 agcgttttga aactctctta tctctattat acgcaagaaa aaataaatga gggtctttat
     8221 cagttagata cgactgtaaa atacgtatct gcagtcaatg attttccagg ttcttataaa
     8281 ccagagggaa gtggtagtct tcctaaaaaa gaagataata aagaatattc tttaaaggat
     8341 ttaattacga aagtatcaaa agaatctgat aatgtagctc ataatctatt gggatattac
     8401 atttcaaacc aatctgatgc cacattcaaa tccaagatgt ctgccattat gggagatgat
     8461 tgggatccaa aagaaaaatt gatttcttct aagatggccg ggaagtttat ggaagctatt
     8521 tataatcaaa atggatttgt gctagagtct ttgactaaaa cagattttga tagtcagcga
     8581 attgccaaag gtgtttctgt taaagtagct cataaaattg gagatgcgga tgaatttaag
     8641 catgatacgg gtgttgtcta tgcagattct ccatttattc tttctatttt cactaagaat
     8701 tctgattatg atacgatttc taagatagcc aaggatgttt atgaggttct aaaatgaggg
     8761 aaccagattt tttaaatcat tttctcaaga agggatattt caaaaagcat gctaaggcgg
     8821 ttctagctct ttctggtgga ttagattcca tgtttctatt taaggtattg tctacttatc
     8881 aaaaagagtt agagattgaa ttgattctag ctcatgtgaa tcataagcag agaattgaat
     8941 cagattggga agaaaaggaa ttaaggaagt tggctgctga agcagagctt cctatttata
     9001 tcagcaattt ttcaggagaa ttttcagaag cgcgtgcacg aaattttcgt tatgattttt
     9061 ttcaagaggt catgaaaaag acaggtgcga cagctttagt cactgcccac catgctgatg
     9121 atcaggtgga aacgattttt atgcgcttga ttcgaggaac tcgcttgcgc tatctatcag
     9181 gaattaagga gaagcaagta gtcggagaga tagaaatcat tcgtcccttc ttgcattttc
     9241 agaaaaaaga ctttccatca atttttcact ttgaagatac atcaaatcag gagaatcatt
     9301 attttcgaaa tcgtattcga aattcttact taccaaaatt ggaaaaagaa aatcctcgat
     9361 ttagggatgc aatcttaggc attggcaatg aaattttaga ttatgatttg gcaatagctg
     9421 aattatctaa caatattaat gtggaagatt tacagcagtt attttcttac tctgagtcta
     9481 cacaaagagt tttacttcaa acttatctga atcgttttcc agatttgaat cttacaaaaa
     9541 ctcagtttgc tgaagttcag cagattttaa aatctaaaag ccagtatcgt catccgatta
     9601 aaaatggcta tgaattgata aaagagtacc aacagtttca gatttgtaaa atcagtccgc
     9661 aggctgatga aaaggaagat gaacttgtgt tacactatca aaatcaggta gcttatcaag
     9721 gatatttatt ttcttttgga cttccattag aaggtgaatt aattcaacaa atacctgttt
     9781 cacgtgaaac atccatacac attcgtcatc gaaaaacagg agatgttttg attcaaaatg
     9841 ggcatagaaa aaaactcaga cgtttattta ttgatttgaa aatccctatg gaaaagagaa
     9901 actctgctct tattattgag caatttggtg aaattgtctc aattttggga attgcgacca
     9961 ataatttgag taaaaaaacg aaaaatgata taatgaacac tgtactttat atagaaaaaa
    10021 tagataggta aaaaatgtta gaaaacgata ttaaaaaagt cctcgtttca cacgatgaaa
    10081 ttacagaagc agctaaaaaa ctaggtgctc aattaactaa agactatgca ggaaaaaatc
    10141 caatcttagt tgggatttta aaaggatcta ttccttttat ggctgaattg gtcaaacata
    10201 ttgatacaca tattgaaatg gacttcatga tggtttctag ctaccatggt ggaacagcaa
    10261 gtagtggtgt tatcaatatt aaacaagatg tgactcaaga tatcaaagga agacatgttc
    10321 tatttgtaga agatatcatt gatacaggtc aaactttgaa gaatttgcga gatatgttta
    10381 aagcaagaga agcagcttct gttaaaattg caaccttgtt ggataaacca gaaggacgtg
    10441 ttgtagaaat tgaggcagac tatacctgct ttactatccc aaatgagttt gtagtaggtt
    10501 atggtttaga ctacaaagaa aattatcgta atcttcctta tattggagta ttgaaagagg
    10561 aagtgtattc aaattagaaa gaataatctt taatgaaaaa acaaaataat ggtttaatta
    10621 aaaatccttt tctatggtta ttatttatct ttttccttgt gacaggattc cagtatttct
    10681 attctgggaa taactcagga ggaagtcagc aaatcaacta tactgagttg gtacaagaaa
    10741 ttaccgatgg taatgtaaaa gaattaactt accaaccaaa tggtagtgtt atcgaagttt
    10801 ctggtgtcta taaaaatcct aaaacaagta aagaaggaac aggtattcag tttttcacgc
    10861 catctgttac taaggtagag aaatttacca gcactattct tcctgcagat actaccgtat
    10921 cagaattgca aaaacttgct actgaccata aagcagaagt aactgttaag catgaaagtt
    10981 caagtggtat atggattaat ctactcgtat ccattgtgcc atttggaatt ctattcttct
    11041 tcctattctc tatgatggga aatatgggag gaggcaatgg ccgtaatcca atgagttttg
    11101 gacgtagtaa ggctaaagca gcaaataaag aagatattaa agtaagattt tcagatgttg
    11161 ctggagctga agaagaaaaa caagaactag ttgaagttgt tgagttctta aaagatccaa
    11221 aacgattcac aaaacttgga gcccgtattc cagcaggtgt tcttttggag ggacctccgg
    11281 ggacaggtaa aactttgctt gctaaggcag tcgctggaga agcaggtgtt ccattcttta
    11341 gtatctcagg ttctgacttt gtagaaatgt ttgtcggagt tggagctagt cgtgttcgct
    11401 ctctttttga ggatgccaaa aaagcagcac cagctatcat ctttatcgat gaaattgatg
    11461 ctgttggacg tcaacgtgga gtcggtctcg gcggaggtaa tgacgaacgt gaacaaacct
    11521 tgaaccaact tttgattgag atggatggtt ttgagggaaa tgaagggatt atcgtcatcg
    11581 ctgcgacaaa ccgttcagat gtacttgatc ctgccctttt gcgtccagga cgttttgata
    11641 gaaaagtatt ggttggccgt cctgatgtta aaggtcgtga agcaatcttg aaagttcacg
    11701 ctaagaacaa gcctttagca gaagatgttg atttgaaatt agtggctcaa caaactccag
    11761 gctttgttgg tgctgattta gagaatgtct tgaatgaagc agctttagtt gctgctcgtc
    11821 gcaataaatc gataattgat gcttcagata ttgatgaagc agaagataga gttattgctg
    11881 gaccttctaa gaaagataag acagtttcac aaaaagaacg agaattggtt gcttaccatg
    11941 aggcaggaca taccattgtt ggtctagtct tgtcgaatgc tcgcgttgtc cataaggtta
    12001 caattgtacc acgcggccgt gcaggcggat acatgattgc acttcctaaa gaggatcaaa
    12061 tgcttctatc taaagaagat atgaaagagc aattggctgg cttaatgggt ggacgtgtag
    12121 ctgaagaaat tatctttaat gtccaaacta caggagcttc aaacgacttt gaacaagcga
    12181 cacaaatggc acgtgcaatg gttacagagt acggtatgag tgaaaaactt ggcccagtac
    12241 aatatgaagg aaaccatgct atgcttggtg cacagagtcc tcaaaaatca atttcagaac
    12301 aaacagctta tgaaattgat gaagaggttc gttcattatt aaatgaggca cgaaataaag
    12361 ctgctgaaat tattcagtca aatcgtgaaa ctcacaagtt aattgcagaa gcattattga
    12421 aatacgaaac attggatagt acacaaatta aagctcttta cgaaacagga aagatgcctg
    12481 aagcagtaga agaggaatct catgcactat cctatgatga agtaaagtca aaaatgaatg
    12541 acgaaaaata accctgagag aggctggagc ctctcttttt tgtgcagttt aggagctaaa
    12601 gggaacagaa tggagaaaat ggaacaaatg tgttttctaa tctgttagac tgtatctaga
    12661 aaggggaaaa ttatgattaa agaattgtat gaagaagtcc aagggactgt gtataagtgt
    12721 agaaatgaat attaccttca tttatgggaa ttgtcggatt gggaccaaga aggcatgctc
    12781 tgcttacatg aattgattag tagagaagaa ggactgg
//
LOCUS       DAVLXH010000054        12517 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00028199
            SAMN33607166-rid17955573.denovo.054, whole genome shotgun sequence.
ACCESSION   DAVLXH010000054 DAVLXH010000000
VERSION     DAVLXH010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607166
            Sequence Read Archive: SRR23725544
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12517)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12517)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721421.1
            Genome Coverage       :: 115x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:42:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,210
            CDSs (total)                      :: 2,161
            Genes (coding)                    :: 2,023
            CDSs (with protein)               :: 2,023
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 73 of 138
            Pseudo Genes (incomplete)         :: 60 of 138
            Pseudo Genes (internal stop)      :: 40 of 138
            Pseudo Genes (multiple problems)  :: 31 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12517
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607166-rid17955573.denovo.054"
                     /strain="AUSMDU00028199"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1349"
     gene            complement(147..2144)
                     /gene="metG"
                     /locus_tag="VYO11_001747"
     CDS             complement(147..2144)
                     /gene="metG"
                     /locus_tag="VYO11_001747"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HEV1596268.1"
                     /translation="MSEKNFYITTPIYYPSGKLHIGSAYTTIACDVLARYKRLMGYDV
                     FYLTGLDEHGQKIQQKAEEAGITPQAYVDGMAVGVKELWQLLDISYDKFIRTTDDYHE
                     KVVAQVFERLLAQDDIYLGEYSGWYSVSDEEFFTESQLAEVFRDEAGNVTGGIAPSGH
                     EVEWVSEESYFLRLSKYQDRLVEFFKAHPEFITPDGRLNEMLRNFIEPGLEDLAVSRT
                     TFTWGVPVPSNPKHVVYVWIDALLNYATALGYAQDEHGNFDKFWNGTVFHMVGKDILR
                     FHSIYWPILLMMLDVKLPDRLIAHGWFVMKDGKMSKSKGNVVYPEMLVERYGLDPLRY
                     YLMRNLPVGSDGTFTPEDYVGRINYELANDLGNLLNRTVSMINKYFDGQIPAYVEGVT
                     EFDHVLAEVAEQSIADFHTHMEAVDYPRALEAVWTLISRTNKYIDETAPWVLDKDEAL
                     RDQLASVMSHLAASIRVVAHLIEPFMMETSRAVLTQLGLEEVSSLENLSLADFPADVT
                     VVAKGTPIFPRLNMEEEIAYIKEQMEGNKPAVEKEWNPDEVELKLNKDEIKFEDFDKV
                     EIRVAEVKEVSKVEGSDKLLQFRLDAGDGEDRQILSGIAKYYPNEQELVGKKVQIVAN
                     LKPRKMMKKYVSQGMILSAEHDGKLTLLTVDPAVPNGSVIG"
     gene            complement(2268..3527)
                     /locus_tag="VYO11_001748"
     CDS             complement(2268..3527)
                     /locus_tag="VYO11_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1596269.1"
                     /translation="MQNLKFAFSSIMAHKMRSLLTMIGIIIGVSSVVVIMALGDSLSR
                     QVNKDMTKSQKNISVFFSPKKSKDGSFTQKQSAFTVSGKEEEVPVEPPKPQESWVQEA
                     AKLKGVDSYYVTNSTNAILTYQDKKVENANLTGGNRTYMDAVKNEIIAGRSLREQDFK
                     EFASVILLDEELSISLFESPQEAINKVVEVNGFSYRVIGVYTSPEAKRSKIYGFGGLP
                     ITTNISLAANFNIDEIASIVFRVNDTSLTPTLGPELARKMTELAGLQQGEYQVADESV
                     VFAEIQQSFSFMTTIISSIAGISLFVGGTGVMNIMLVSVTERTREIGLRKALGATRAN
                     ILIQFLIESMILTLLGGLIGLTIASGLTALAGLLLQGLIEGIEVGVSIPVALFSLAVS
                     ASVGMIFGVLPANKASKLDPIEALRYE"
     gene            complement(3529..4230)
                     /locus_tag="VYO11_001749"
     CDS             complement(3529..4230)
                     /locus_tag="VYO11_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1596270.1"
                     /translation="MKQLISLKNIFRSYRNGDQELQVLKNINLEVNEGEFVAIMGPSG
                     SGKSTLMNTIGMLDTPTSGEYYLEGQEVAGLGEKQLAKVRNQQIGFVFQQFFLLSKLN
                     ALQNVELPLIYAGVSSSKRRKLAEEYLDKVELTERSHHLPSELSGGQKQRVAIARALV
                     NNPSIILADEPTGALDTKTGNQIMQLLVDLNKEGKTIIMVTHEPEIAAYAKRQIVIRD
                     GVISSDSAQLGKEEN"
     gene            complement(4214..5413)
                     /locus_tag="VYO11_001750"
     CDS             complement(4214..5413)
                     /locus_tag="VYO11_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HEV1596271.1"
                     /translation="MKKKNGKAKKWQLYAAIGAASVVVLGAGGILLFRQPSQTAVKDE
                     PTHLVVAKEGSVASSVLLSGTVTAKNEQYVYFDASKGDLDEILVSVGDKVSEGQALVK
                     YSSSEAQAAYDSASRAVAKADRHINELNQARNEAASAQAPQLPAPVGGEDATVQSPTP
                     VAGNSVASIDAQLGDARDARADAAAQLSKAQSQLDATTVLSTLEGTVVEVNSNVSKSP
                     TGASQVMVHIVSNENLQVKGELSEYNLANLSVGQEVSFTSKVYPDKKWTGKLSYISDY
                     PKNNGEAASPAAGNNTGSKYPYTIDVTGEVGDLKQGFSVNIEVKSKTKAILVPVSSLV
                     MDDSKNYVWIVDEQQKAKKVEVSLGNADAENQEITSGLTNGAKVISNPTSSLEEGKEV
                     KADEATN"
     gene            5699..7045
                     /gene="gor"
                     /locus_tag="VYO11_001751"
     CDS             5699..7045
                     /gene="gor"
                     /locus_tag="VYO11_001751"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HEV1596272.1"
                     /translation="MREYDIIAIGGGSGGIATMNRAGEHGAKAAVIEEKKLGGTCVNV
                     GCVPKKIMWYGAQIAETFHQFGEDYGFKTTDLNFNFATLRRNREAYIDRARSSYDGSF
                     KRNGVDLIEGHAEFVDSHTVSVNGELIRAKHIVIATGAHPSIPNIPGAELGGSSDDVF
                     AWEELPESVAILGAGYIAVELAGVLHTFGVKTDLFVRRDRPLRGFDSYIVEGLVKEME
                     RINLPLHTHKVPAKLEKTAKGITIHFEDGTSHTASQVIWATGRRPNVKSLQLEKAGVT
                     LNERGFIQVDEYQNTVVEGIYALGDVTGEKELTPVAIKAGRTLSERLFNGKTTAKMDY
                     STIPTVVFSHPAIGTVGLTEEQAIKEYGQDQIKVYKSSFASMYSACTRNRQESRFKLI
                     TAGSEEKVVGLHGIGYGVDEMIQGFAVAIKMGATKADFDATVAIHPTASEEFVTMR"
     gene            7242..7778
                     /locus_tag="VYO11_001752"
     CDS             7242..7778
                     /locus_tag="VYO11_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000709035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HEV1596273.1"
                     /translation="MKKAHVYAIPAIGAALIAALAQISLPIGPVPFTLQNFAIGLIAT
                     VFRPREAVLSAGLYLLLGAIGLPVFAGGGAGFQALVGPTAGYLWFYLVYSGLTSSLTN
                     SKSGVVKIFLANLLGDALVFVGGILSLHFLAGMAFEKALAVGVLPFIIPDLGKLLAIS
                     FISRPLLQRLKNQAYFTN"
     gene            7829..7915
                     /locus_tag="VYO11_001753"
                     /pseudo
     CDS             7829..7915
                     /locus_tag="VYO11_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(7984..8199)
                     /locus_tag="VYO11_001754"
     CDS             complement(7984..8199)
                     /locus_tag="VYO11_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000807422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HEV1596274.1"
                     /translation="MAEFTFEIEEHLLTLSENEKGWTKEINRVSFNGAPAKFDIRAWS
                     PDHTKMGKGITLSNEEFQTMVDAFKGN"
     gene            8297..8617
                     /locus_tag="VYO11_001755"
     CDS             8297..8617
                     /locus_tag="VYO11_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001216095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1596275.1"
                     /translation="MRHKFQQVLNKIHDFLNGYDQPDQTETNSLTATIEEAIQKQTAV
                     HLILSETSFTGDIIKYDQQGQQIIVKNFSKNVSRIIRISDIQRLRFVPSTVQTAQKNR
                     FKKE"
     gene            complement(8647..8985)
                     /locus_tag="VYO11_001756"
     CDS             complement(8647..8985)
                     /locus_tag="VYO11_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1596276.1"
                     /translation="MQVIKRNGEIAEFNPDKIYQAILKAAQTVYVLTDDLRQNLAQVT
                     KKVVLDLQEAKVERATISMIQSMVEHRLLGAGYITIAEHYISYRLQRDLERSGYGDHI
                     AVHLHFEQIR"
     gene            complement(8997..9716)
                     /gene="trmD"
                     /locus_tag="VYO11_001757"
     CDS             complement(8997..9716)
                     /gene="trmD"
                     /locus_tag="VYO11_001757"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HEV1596277.1"
                     /translation="MKIDILTLFPEMFSPLEHSIVGKAREKGLLDIQYHNFRENAEKA
                     RHVDDEPYGGGQGMLLRAQPIFDSFDAIEKKNPRVILLDPAGKQFDQAYAEDLAQEEE
                     LIFICGHYEGYDERIKTLVTDEISLGDYVLTGGELAAMTMIDATVRLIPEVIGKESSH
                     QDDSFSSGLLEYPQYTRPYDYRGMVVPDVLMSGHHEKIRQWRLYESLKKTYERRPDLL
                     EHYQLTVEEEKMLAEIKENKE"
     gene            complement(9706..10224)
                     /gene="rimM"
                     /locus_tag="VYO11_001758"
     CDS             complement(9706..10224)
                     /gene="rimM"
                     /locus_tag="VYO11_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HEV1596278.1"
                     /translation="MNYFNVGKIVNTQGLQGEMRVLSVTDFAEERFKKGAELALFDEK
                     DQFVQTVTIASHRKQKNFDIIKFKDMYHINTIEKYKGYSLKVAEEDLNDLDDGEFYYH
                     EIIGLEVYEGDSLVGTIKEILQPGANDVWVVKRKGKRDLLLPYIPPVVLNVDIPNKRV
                     DVEILEGLDDED"
     gene            complement(10255..11043)
                     /locus_tag="VYO11_001759"
     CDS             complement(10255..11043)
                     /locus_tag="VYO11_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000819180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEV1596279.1"
                     /translation="MKRFEVSTEIGSLSVAYQKQKKVLVCLNGAGLLPSYENFSLILE
                     KPPPTIGYLTIDFPNTGRSPIHDQAGKNLDNLADVVYEVLEELGISEYILCAHSWSGI
                     LACKLLEKPIKCQTLVAIEPTTKKVMFADFSENPYPEMEEQMRLIDECGPELYFKNLT
                     QATFSPETNKKIWELMQEKGLELENQDPEFQISGEITEEDFEDVSIEAHIPVFVFCQP
                     YREKEYRESEYWTSNTKLILGGNHHYLQWSESEKIAAIIRELSE"
     gene            complement(11147..11390)
                     /locus_tag="VYO11_001760"
                     /pseudo
     CDS             complement(11147..11390)
                     /locus_tag="VYO11_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000779614.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
     gene            complement(11620..11859)
                     /locus_tag="VYO11_001761"
     CDS             complement(11620..11859)
                     /locus_tag="VYO11_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HEV1596280.1"
                     /translation="MDTIENLIIAIVKPLISQPDALTIKIEDTPEFLEYHLNLDQSDV
                     GRVIGRKGRTISAIRTIVYSVPTEYKKVRIVIDEK"
     gene            complement(11879..12151)
                     /gene="rpsP"
                     /locus_tag="VYO11_001762"
     CDS             complement(11879..12151)
                     /gene="rpsP"
                     /locus_tag="VYO11_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HEV1596281.1"
                     /translation="MAVKIRLTRMGSKKKPFYRINVADSRSPRDGRFIETVGTYNPLV
                     AENQVTLKEDRVLAWLANGAQPSDTVRNILSKEGVLKKFHDSKFSK"
     gene            12321..>12517
                     /locus_tag="VYO11_001763"
     CDS             12321..>12517
                     /locus_tag="VYO11_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000953868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1596282.1"
                     /translation="MLSVNTILEKFYKEHQVKPFISPERDLDTWLLSPKPVPKRNMDL
                     LVDDSLAGDIILLWRIQFGTFT"
BASE COUNT         3608 a         2722 c         2269 g         3918 t
ORIGIN      
        1 catgttttga gctgacttcg tcagttctat ctacaacctc aaaacagtgt tttgagcaac
       61 ctgcggctag cttcctagtt tgctctttga ttttcattga gtataaataa aaaaacagaa
      121 ctagcctgaa ctagtcctgt ctacttttac ccaatcacac ttccatttgg tacagctgga
      181 tcaactgtga gaagggttaa tttgccatca tgttcagctg agagaatcat accctggctg
      241 acatattttt tcatcatttt acgtggtttg aggttagcaa cgatttgaac tttcttgccg
      301 accaattctt gttcatttgg atagtatttt gcaattcctg aaagaatctg acgatcttct
      361 ccatcaccag catccaagcg gaattgaagc aacttatctg aaccttctac tttagacact
      421 tctttgactt ctgcgacacg gatttcaacc ttgtcaaagt cttcaaactt gatttcatcc
      481 ttgtttagtt tgagctcaac ttcgtccgga ttccattctt tttcgactgc tggtttattg
      541 ccttccattt gttccttgat ataggcgatt tcttcttcca tatttagacg tggaaagata
      601 ggtgttcctt tggcaactac agtcacatct gctgggaagt cagccaaact caagttttca
      661 agactagaaa cttcttccaa accaagttga gtcaaaactg cacgactagt ttccatcata
      721 aatggttcaa tcaagtgagc aactacacga atgctggctg ccaagtggct catgacactt
      781 gccaattggt cacgaagagc ttcatccttg tccaagaccc atggtgcagt ctcatcgatg
      841 tatttattgg tacgagagat cagagtccag actgcttcaa gcgcacgtgg atagtcaact
      901 gcttccatgt gtgtatggaa gtctgcgatt gattgttctg caacctcagc aagaacatga
      961 tcaaattcag tcacaccttc tacataggca gggatttgtc catcaaagta cttattaatc
     1021 atggaaaccg tacggttaag gaggttccca aggtcattag ccaattcata gttgatacgg
     1081 ccgacatagt cttcaggagt aaaggttccg tctgaaccaa ctggaaggtt acgcatgagg
     1141 tagtaacgaa gtggatctag tccataacgc tctaccaaca tttcagggta aacgacattc
     1201 ccttttgact tagacatttt tccgtctttc atgacaaacc aaccatgggc aatcaaacga
     1261 tcaggtaatt taacatccaa catcataaga aggattggcc agtagataga gtggaagcga
     1321 aggatatctt ttcctaccat atggaagact gttccattcc agaacttgtc aaagttacca
     1381 tgttcgtctt gagcgtagcc aagagctgtc gcatagttaa gaagggcatc aatccaaacg
     1441 tagacaacgt gttttggatt tgatgggaca ggcactcccc atgtaaaggt tgtacgagat
     1501 accgccaaat cttccaaacc tggctcgatg aagttgcgta gcatttcatt aaggcgacca
     1561 tctggcgtga taaattcagg atgagctttg aaaaattcga ccaaacggtc ttggtatttg
     1621 ctaaggcgaa ggaagtatga ttcttcagaa acccattcaa cctcatgacc tgatggagca
     1681 ataccaccag tcacatttcc agcttcatca cggaaaactt ctgccagctg gctttctgta
     1741 aagaattctt cgtctgatac tgaataccaa ccagagtatt cacccaagta gatatcatct
     1801 tgagcaagta agcgttcaaa gacctgtgca acaacttttt catggtagtc atcagttgta
     1861 cggataaatt tatcgtatga gatatctagt aattgccaga gttctttaac tccaaccgcc
     1921 attccatcaa cataggcttg aggtgtaata ccagcttctt ccgctttctg ctggattttc
     1981 tgaccatgtt catcaagacc tgtcagataa aatacatcgt agcccatcag gcgtttgtaa
     2041 cgtgctagga catcacatgc gatagttgtg taggcagaac cgatatgaag tttcccagat
     2101 ggatagtaaa tcggcgttgt aatataaaaa tttttttcag acataatttt tcctttccag
     2161 gcaaatgaaa cctgtttttc taacacttca ttatatcata tttttaatga atttcgatag
     2221 ggaaatccat acaaaaacaa gatagacgag tgtccatctt gttgatctca ttcataacga
     2281 agggcttcaa ttggatcaag tttcgatgcc ttgttggctg gcaagactcc aaaaatcata
     2341 ccaacactag ccgaaactgc aagactaaat agggcaactg ggattgatac tccaacttct
     2401 ataccttcta ttaaaccttg cagtaacaaa cctgctaagg cagttaaacc acttgcaatt
     2461 gtcaagccaa ttaagccacc taacaaggtc aaaatcatgg attcaatcaa aaactgaatt
     2521 aaaatattgg cacgtgttgc gcccaaagcc ttacgaagac caatctcacg agtgcgctct
     2581 gtcaccgaaa ccagcatgat gttcatgaca ccagttcctc caacaaagag agaaatccct
     2641 gcgatggaac taataatcgt cgtcataaaa ctaaacgatt gttgaatttc tgcaaataca
     2701 acggactcat ctgccacctg gtattctccc tgttgtaagc ctgcaagctc tgtcattttt
     2761 cgtgccagtt ctggacccag agttggggtt aaactggtat cattcactcg aaagacaata
     2821 ctagctattt catctatatt aaaattcgca gcaagggaga tattggtagt aataggcaag
     2881 ccaccaaacc catatatttt tgacctttta gcctccggac tagtataaac cccaatgacc
     2941 cggtaactaa atccattgac ttctacaacc ttgttaatag cctcttgagg agattcaaat
     3001 aaactaatgg acaattcctc atctagcaaa atgacacttg caaactcttt gaaatcttgc
     3061 tctctcagac tacgacctgc aataatttca ttcttaacag cgtccatgta agttctgttt
     3121 ccacctgtca aattagcatt ctcaaccttt ttatcttgat aggtcaagat ggcattcgtt
     3181 gaattggtta catagtaact atccactccc ttcagtttag ctgcctcttg gacccaggat
     3241 tcttgcggtt ttggcggttc aacaggaact tcctcttcct ttccagaaac cgtaaaagct
     3301 gattgtttct gagtaaaaga cccatcttta ctttttttag gagagaaaaa gacgctaata
     3361 tttttctgag atttagtcat atctttattg acttgacgag atagggaatc acccaaagcc
     3421 ataatcacaa caactgatga aacaccgata ataatcccaa tcatagtaag caaagaacgc
     3481 atcttgtgag ccatgataga tgaaaaggca aatttcagat tctgcatctt agttttcctc
     3541 ctttcctaac tgagcactgt cagacgaaat gaccccatcc cgaatgacaa tctgacgttt
     3601 ggcataggca gcaatctcag gctcatgcgt taccatgata atggtttttc cttctttatt
     3661 caaatcaacc aataattgca taatttggtt acctgttttg gtatccaagg ctcctgtcgg
     3721 ttcatccgct aggataatag aaggattgtt taccaaggca cgcgcaatgg ctacacgttg
     3781 cttttgacca ccagataatt ctgaaggtaa atggtgacta cgttctgtca attcaacctt
     3841 gtctaaatat tcctcagcca acttgcgacg ttttgaagac gaaactcctg cgtaaatcaa
     3901 gggcaattct acattttgca gagcattgag cttcgataga agaaagaact gctgaaagac
     3961 aaaaccgatt tgttggttac ggaccttagc tagttgtttt tcaccaagcc cagccacttc
     4021 ttgaccttca agataatatt ctccactggt tggtgtatcc aacatgccaa tcgtattcat
     4081 cagagtggac ttaccagacc cagatggtcc catgatggct acaaattcac cctcattcac
     4141 ttctagattg atatttttga gaacctgcag ttcttggtca ccattacggt aacttctgaa
     4201 gatatttttt agactaatta gttgcttcat cagccttcac ctcttttcct tcttccaagg
     4261 aagatgttgg attactgatg accttagcac cgttcgttaa accagaagtg atttcttgat
     4321 tttctgcgtc agcatttccc aatgaaacct caactttttt agccttttgt tgttcatcca
     4381 caatccagac ataattttta ctatcatcca ttactagact gctaacagga acaagaatag
     4441 ccttagtttt gcttttaacc tcaatgttga cagaaaaacc ttgtttcaaa tcaccaacct
     4501 cgcctgtcac atcaatagta taagggtatt tagaacctgt attattcccg gctgctggac
     4561 tagctgcttc accattgttt ttaggatagt cagaaatata gcttaatttc ccagtccatt
     4621 ttttatcagg atacacttta gaagtaaagc ttacttcttg acctacagaa aggttggcta
     4681 gattgtactc agacaattct cccttgactt gtaaattttc attgctgaca atatgaacca
     4741 taacttgact cgcccctgtt ggagatttag aaacattgct attgacttcg actacagttc
     4801 cctctagggt actgagaaca gttgttgcat ccaattgact ttgagccttg cttaattgcg
     4861 ctgcagcatc tgcacgcgca tcacgggcat cacccaattg agcatcaata gaagcaacag
     4921 aatttccagc cactggagtt gggctttgca ccgttgcatc ttctcctcct actggcgctg
     4981 gtaactgtgg agcctgagct gaagcggctt catttcgtgc ttgattgagt tcattgatat
     5041 gacgatctgc cttagctact gctcgactag ctgaatcata ggccgcctgc gcttctgaac
     5101 tactgtactt gactaaagcc tgcccttcgc tgaccttatc gcccacagaa acaaggattt
     5161 catctaaatc acccttacta gcatcaaaat aaacatattg ttcatttttt gctgttactg
     5221 tccctgacaa taaaacagag gatgccacgc ttccttcctt ggcaacaaca agatgagtag
     5281 gctcatcttt tacagcagtc tgagaaggtt gtctaaaaag taaaatcccc ccggcaccca
     5341 atacaactac actcgcagca ccgattgctg catacagttg ccacttttta gctttaccat
     5401 tctttttctt cataatgaaa ctccttttct tttttacaat actttgctat tataccaaat
     5461 ttccctccag caaacaatgc agttcagatg gaaataatgg cagttcagga ttaaacaatc
     5521 gttcggaatt ttgcttttat attgtactag atatataata cactatcttg acttatttgg
     5581 caagcttttt tgcaattttt tgtgcgtagc agatttttgc aatcaaatca aaaaaagaat
     5641 aaaatataac tatcaaaaaa gacactctac tatttaaaag attacaaagg agttttcaat
     5701 gagagaatat gatatcattg ctatcggtgg aggtagcgga ggaatcgcta ccatgaaccg
     5761 tgctggtgaa catggagcca aagcagccgt tattgaggaa aagaaattag gtggaacctg
     5821 tgtcaacgtc ggttgtgttc ctaaaaaaat catgtggtac ggggcgcaaa tcgctgagac
     5881 tttccatcaa tttggagaag actacggctt taagactact gatcttaact ttaactttgc
     5941 aaccctacgt cgcaatcgtg aagcctacat tgatcgcgct cgttcttctt atgatggtag
     6001 ttttaaacgc aacggtgtag acttgattga aggtcatgct gaatttgtag attctcatac
     6061 tgtaagcgta aatggtgaac tgattcgtgc taaacatatc gtgattgcta caggtgccca
     6121 tccaagtatt cctaatattc ctggtgctga gctaggtggc tcttctgacg atgtatttgc
     6181 ctgggaagaa cttccagagt cagttgccat tctaggcgct ggttatatcg ccgttgaatt
     6241 agctggcgta ctccacactt ttggtgtcaa gacagatctc tttgttcgcc gcgatcgtcc
     6301 tttacgtggt tttgattcct acatcgttga aggtttggtc aaggaaatgg aaagaataaa
     6361 cttgccactt catactcaca aagtccctgc caagttagaa aaaactgcta aaggcattac
     6421 cattcatttc gaggatggta ccagtcacac agctagccaa gttatctggg ctacaggtcg
     6481 ccgtccaaac gttaagagct tgcaacttga aaaagctgga gtgactctga atgaacgtgg
     6541 ctttatccaa gtagatgaat accaaaatac tgttgttgag ggaatctatg ctctaggtga
     6601 tgtaacgggc gagaaagaac tgactccagt tgcaatcaag gccggacgta ccctatctga
     6661 acgtctcttt aacggaaaaa ctactgcaaa aatggattac tcaactattc caactgttgt
     6721 cttttcacac cctgctatcg gaactgttgg tttgacagaa gagcaagcta ttaaagaata
     6781 cggtcaagac caaatcaagg tttataaatc aagctttgca tctatgtact ctgcttgcac
     6841 tcgcaaccgt caagaatccc gtttcaaact cataacagct ggttcagaag aaaaagttgt
     6901 cggacttcat ggaattggct acggcgttga tgaaatgatt cagggatttg ccgttgctat
     6961 caaaatggga gcaaccaagg ctgactttga tgcaactgtg gcaattcacc caactgcatc
     7021 tgaagaattt gtaaccatgc gttaatcgaa acaaaagaag ctgatataaa tatgtctgct
     7081 tcttttttaa tgattttcga atcaacaaaa aaattatcca acttgactag tcacgaaaat
     7141 cggctgttac agtttttgtt accttgtttt taaaaaatgg ttgacatcga ctcctatatg
     7201 agtataatag ttactataca ttagaaaaga ggttaactat tttgaaaaaa gctcacgttt
     7261 atgctatccc tgctattggg gctgctctca ttgctgcttt ggcacaaatc agtcttccaa
     7321 ttggacctgt tcccttcact ctgcaaaact ttgcaattgg cttgattgct actgtcttta
     7381 gaccgagaga ggctgtactt tctgctggac tctatcttct tctaggtgct atcggtcttc
     7441 ctgtctttgc aggaggtgga gctggttttc aggctttagt tggccctact gcaggctatc
     7501 tttggtttta tctcgtttac tctggactta cttcctctct aaccaacagc aagagtggtg
     7561 ttgttaagat ttttcttgca aacctcttgg gtgatgccct tgtctttgtc ggcgggattc
     7621 tcagcttgca tttcctagct ggaatggcat ttgaaaaagc tcttgctgtg ggggttcttc
     7681 cctttatcat tccagacctt ggcaaacttc tggctattag ttttattagc cgtcccctac
     7741 ttcaacgcct taaaaatcag gcttacttta ctaactaaaa aaggatatcg agttatcatg
     7801 actcaatatc cttttctttt attttgaaaa cttatactca atgaaaatca aagagcaaac
     7861 taggaagcta gccgcaggct gctcaaaaca ctgttttgag gttgtggatg aaactgacga
     7921 agtcagtaac catacatacg gcaaggcaaa gctgacgcgg tttgaagaga ttttcgaaga
     7981 gtattagttg cctttaaagg catccaccat cgtttgaaat tcttcatttg agagagtaat
     8041 ccctttgccc attttagtat ggtctggact ccaagcacga atatcaaact ttgcaggggc
     8101 accattaaag ctcacacggt taatttcctt ggtccaacct ttttcgtttt cagaaagagt
     8161 caacaagtgc tcttcgattt caaatgtaaa ttctgccatt ttcttctcct tttttagttt
     8221 cattagttta ttcgtaaaat cttgtagatt ttaggaaaat tttatataat attgatataa
     8281 aagaagggag gccaatatga gacataaatt ccagcaagtt ctaaataaaa tacatgattt
     8341 tttaaatgga tatgaccaac ctgaccagac tgaaaccaac tcccttacag ccactattga
     8401 agaggctatc cagaaacaaa ccgctgttca ccttatcttg tctgagacaa gctttacagg
     8461 tgacatcatc aaatatgatc agcaaggcca gcaaattatc gtgaaaaatt tttccaaaaa
     8521 tgtgagccgg attatccgta taagcgatat tcaacgcctg cgatttgtcc cctcaactgt
     8581 ccaaacagcc caaaaaaata gatttaagaa agagtgagat gtagttgctt catcccactc
     8641 tttttcttag cgaatttgtt caaaatgtaa atgaactgca atatgatctc cataaccact
     8701 tctttccaag tcacgttgta aacgatagga aatgtagtgt tctgcaatgg taatgtaacc
     8761 tgcgcccaat aaacgatgtt caaccataga ttgaatcata ctgatagtcg cacgttccac
     8821 cttggcttct tgtaaatcca aaactacctt cttagtgact tgagcaagat tttgacgcaa
     8881 atcatctgtc aaaacataaa cagtttgggc tgccttcaag atggcttggt aaatcttatc
     8941 tggattaaat tcagcaattt cgccattacg tttgattact tgcataggtt tctcctttat
     9001 tctttgtttt ctttgatttc tgccagcatt ttttcttctt ctactgtcag ttgataatgt
     9061 tcaagtaaat ctggtctgcg ctcgtaggtt ttctttaaac tctcgtacaa tcgccactga
     9121 cgaatctttt catggtggcc actcatcaat acatctggca cgaccatgcc tcgataatca
     9181 tagggacgtg tgtactgagg atattctaaa agacctgaag aaaaactatc atcttggtgg
     9241 ctagactcct tgccaatcac ttctggaatc aggcgaactg tagcatcaat catggtcata
     9301 gctgccaatt ctccaccagt gaggacatag tcgcctaggg aaatctcatc tgttaccaag
     9361 gtcttaatgc gctcatcata accctcatag tgcccacaga taaagattag ctcttcctct
     9421 tgagccaaat cttcagcata agcctgatca aactgctttc cagcaggatc gaggagaata
     9481 acgcgcggat ttttcttttc aatagcatca aaggaatcga aaataggttg tgctctgagc
     9541 aacataccct gaccgcctcc gtagggctca tcatctacat gacgggcctt ttcagcattt
     9601 tctcgaaaat tatgatactg gatatccaag agcccttttt ctcgagcctt tccaacgatt
     9661 gagtgctcca gtggagaaaa catctctgga aagagggtta aaatatcaat cttcatcgtc
     9721 taacccttct aagatttcca catcgacccg tttatttgga atatcaacat tgagaaccac
     9781 tggtgggata taaggtaaaa gcaaatcacg tttgcctttt cgtttgacca cccagacatc
     9841 attagcacct ggttgcagga tttccttgat ggttccaacc aagctatcac cctcatagac
     9901 ttccaaaccg ataatctcgt gatagtaaaa ttcaccatcg tctaggtcat tcaaatcttc
     9961 ctcagcgacc ttgagactat atcccttgta cttttcgata gtattgatat ggtacatatc
    10021 tttgaattta ataatgtcaa agttcttctg tttacggtgg ctagcgatgg tcactgtttg
    10081 gacaaactga tctttttcat caaacaaagc cagctcagct ccttttttaa accgttcttc
    10141 tgcaaaatcc gtcacagaca agactcgcat ctcaccctgt aatccctgcg tattaacgat
    10201 tttcccaaca ttaaagtagt tcatcttgtc tcctgtaatc tccttttttc catcttattc
    10261 tgacaattct cgaataatag ccgcaatttt ttccgattct gaccattgta aataatggtg
    10321 attccctcct aaaatgagtt tagtattgga agtccaatat tctgattctc tgtactcttt
    10381 ttctctataa ggctgacaaa aaacaaatac aggaatatga gcttctatag atacatcctc
    10441 aaaatcttcc tcagtaatct ctccagatat ctgaaattct ggatcttgat tttccaactc
    10501 taagcctttt tcttgcatca attcccagat ttttttattc gtttcaggac taaatgttgc
    10561 ttgagttaag ttcttaaaat aaagttcagg accacactcg tcaatcagcc tcatctgctc
    10621 ttccatttct ggataaggat tttctgaaaa atcagcaaac atgacttttt tagttgtcgg
    10681 ttcaattgct actaaagtct gacacttaat tggtttctcg agtaatttgc aagctaaaat
    10741 tccactccaa ctatgtgcac aaagtatata ttcagaaatc cctaattctt caagtacttc
    10801 ataaaccaca tctgcaagat tatctagatt ttttccagct tggtcatgaa tcggactcct
    10861 acctgtgttc ggaaaatcaa ttgtcaaata accaattgta ggaggaggtt tttcaagtat
    10921 aagtgaaaaa ttttcataac ttggtagcaa acctgctccg tttagacaaa ctagcacttt
    10981 cttttgcttt tgataagcaa cagagagact accaatttct gtagatactt caaacctctt
    11041 cataaagaaa tccactcatt ctatataatg aattattaaa aatccttatc ctttatttta
    11101 tcacgttcca aggattttct caagttggag gaaggggaca acatctctac tttcccttca
    11161 aaaatccttc caaatcatgt ttatgttggt aattaacggc tgcggttttg tctttctcaa
    11221 agacagtctt ggtaaggtca atatgattaa tagctacgat tgcgacggtg tagtaaatga
    11281 tatcagccag ttctctggca agttcctcgt tcgaatccta tcccttcttt tcgaccagag
    11341 cgcctattca aaacctcggc tacttctccg acttcctcca ctaacttcat aaagagacct
    11401 tcatcagtcc gagactgctg ttaatgttcg agtaagtagt cttggaattg cctaaacgtt
    11461 caatctttta tagtatattg aaactagaat agtacacctt tacttctaaa acattgttag
    11521 aaatcgattt gactgtcctg atcgatttgt cctgttatta tttcatttta ctatatcttc
    11581 tattccacac aaaaaagcga gacatccgtc ccgcccttct tatttttcgt caataacgat
    11641 tcttactttt ttgtattcag ttgggacaga gtagacaatc gttcttatcg cagaaatagt
    11701 gcgaccctta cgaccgatta cacgacccac atcgctttga tcaagattca aatgatattc
    11761 caaaaattct ggtgtatctt caatcttgat agttaaggca tctggttgtg aaattaaggg
    11821 tttcacaatc gcaataatga gattttcaat cgtatccatc tgtcaaccta ctttaaactt
    11881 attttgagaa tttagaatcg tggaattttt tcaatacgcc ttcttttgaa aggatgttac
    11941 gtactgtgtc tgaaggttga gctccattag ccaaccatgc aagaacgcgg tcttctttca
    12001 aagttacttg gttttcagca acaagtgggt tgtaagttcc aactgtttcg atgaaacgtc
    12061 cgtcacgtgg tgaacgtgaa tctgctacgt tgatacggta gaaaggtttt ttcttagaac
    12121 ccatacgagt caaacggatt ttaactgcca tttttaaagt ctcatttctt taatttttta
    12181 tttcggtgaa atagctgagc tatttagcac atgttctatt atagcagatt tctggcaggt
    12241 gtcaagaaaa aaacttgaca gactataaat ttcttaaagc atttaaaaat ttgttagaat
    12301 aggaaataaa tgtttgaaag atgctatccg tgaatactat tttagaaaaa ttttataaag
    12361 aacaccaagt caaacccttc atatcgcctg aacgagattt ggatacttgg cttctaagtc
    12421 ccaagcccgt tcccaagcga aatatggact tattagtaga tgattcacta gcaggagata
    12481 tcattttact atggagaatc cagtttggta cttttac
//
LOCUS       DAVLXH010000055        12279 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00028199
            SAMN33607166-rid17955573.denovo.055, whole genome shotgun sequence.
ACCESSION   DAVLXH010000055 DAVLXH010000000
VERSION     DAVLXH010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607166
            Sequence Read Archive: SRR23725544
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12279)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12279)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721421.1
            Genome Coverage       :: 115x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:42:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,210
            CDSs (total)                      :: 2,161
            Genes (coding)                    :: 2,023
            CDSs (with protein)               :: 2,023
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 73 of 138
            Pseudo Genes (incomplete)         :: 60 of 138
            Pseudo Genes (internal stop)      :: 40 of 138
            Pseudo Genes (multiple problems)  :: 31 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12279
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607166-rid17955573.denovo.055"
                     /strain="AUSMDU00028199"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1349"
     gene            31..840
                     /locus_tag="VYO11_001764"
     CDS             31..840
                     /locus_tag="VYO11_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000926538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HEV1596283.1"
                     /translation="MLLQKELIPMIEANLPNMAYAEKDIAKFFLKQQPLNDYSSKALC
                     EYLNVSKATLTRFAKKCGFKGFRQFIFKYQEMIHEKEKLALYTEATEKVLSDYEEMLR
                     KTYTVLDEVQLERIAEMIETAERVYLYGKGSSVLALQEMKMRFMRLGVIGEVLSDEDM
                     ILWSSLLLNENCLVIGASISGQTDIVLEGLQKAADKGAKTVLMTTRKFDEEDCFFDEL
                     LLLASTDHLSYGNRISPQFPILLITDCLFSNYLESPERQYYYNQTIIHKEE"
     gene            845..1546
                     /locus_tag="VYO11_001765"
     CDS             845..1546
                     /locus_tag="VYO11_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HEV1596284.1"
                     /translation="MSQIWTKEKFISQVQGGVIVSCQALPGEALYNEEFSLMPFMAKA
                     ALEAGAVGIRANSVRDIKAIQKVVDLPIIGIIKRDYPPQEPYITATMKEVDELVECGT
                     TVIAFDATLRPRYDGLVVSEFIKKIKEKYPNQLLMADVSNLDEGLYAFKSGVDFVGTT
                     LSGYTSTSVQSDEPDFELMKKLADFNIPVIAEGKIHYPEQLKKAYSLGVTSVVIGGAI
                     TRPKEIAQRFINVIK"
     gene            1571..2488
                     /locus_tag="VYO11_001766"
     CDS             1571..2488
                     /locus_tag="VYO11_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminate lyase"
                     /protein_id="HEV1596285.1"
                     /translation="MKDLTKYKGVIPAFYACYDENGEISQDRVKSLVQYFIDKGVKGI
                     YVNGSSGECIYQSVEDRKQIIEAVMEVAKGKLTVINHIACNNTKDSIELAKHSESVGV
                     DAIAAIPPIYFKLPEYSIAAYWNAMSEAASNTDFIIYNIPQLAGVALTGSLYATMRQN
                     PRVIGVKNSSMPVQDIQMFVAAGGEDYIVFNGPDEQYLGGRLMGAEAGIGGTYGVMPD
                     LFLKLESLIQERDLDTAKKLQYAINEVIYKMISGKANMYAVAKEVLRLNEKLDLGSVR
                     QPLEALAEGDLEVAKQAAELIQQARKEFL"
     gene            2516..4057
                     /locus_tag="VYO11_001767"
     CDS             2516..4057
                     /locus_tag="VYO11_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000537364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:solute symporter"
                     /protein_id="HEV1596286.1"
                     /translation="MGTTGFTIIDLIILIVYLLAVLVAGIYFSKKEMKGKEFFKGDGS
                     VPWYVTSVSIFATMLSPISFLGLAGSSYAGSWILWFAQLGMVVAIPLTIRFILPIFAR
                     IDIDTAYDYLDKRFNSKALRIISALLFIIYQLGRMSIIMYLPSAGLSVLTGIDINILI
                     ILMGVVAIVYSYTGGLKSVLWTDFIQGVILISGVVLALFVLIANIKGGFGAVAETLAN
                     GKFLAANEKLFDPNLLSNSIFLIVMGSGFTILSSYASSQDLVQRFTTTQNIKKLNKML
                     FTNGVLSLATATVFYLIGTGLYVFYQVQNADSAASNIPQDQIFMYFIAYQLPVGITGL
                     ILAAIYAASQSTISTGLNSVATSWTLDIQDVISKNMSDNRRTKIAQFVSLAVGLFSIG
                     VSIVMAHSDIKSAYEWFNSFMGLVLGLLGGVFILGFVSKKANKQGAYAALIVSTIVMV
                     FIKYFLPPTAVSYWAYSLISISVSVVSGYIVSVLTGNKVSAPKYTTIHDITEIKADSS
                     WEVRH"
     gene            4076..4534
                     /locus_tag="VYO11_001768"
     CDS             4076..4534
                     /locus_tag="VYO11_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HEV1596287.1"
                     /translation="MIISEQSDFKRYASVNKYFSKVCDFLENTNLTDLVDGKIDIDGE
                     NVFANCMTYLADGVPGDIFETHKKYLDIHIVVENTEKMAVTSPVRAQSRVPFSEEKDI
                     AFYDSKDYQIVELLPGNMLVTFEEDLHQPKIHCNDETVKKLVIKVLNEEK"
     gene            4536..6758
                     /locus_tag="VYO11_001769"
     CDS             4536..6758
                     /locus_tag="VYO11_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000739354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exo-alpha-sialidase"
                     /protein_id="HEV1596288.1"
                     /translation="MKKNIKQYVTLGTVVVLSAFVANSVAAQETETSEVSTPKLVQPV
                     APTTPISEVQPTSDNSSEVTVQPRTVETTVKDPSSTAEETPVLEKNNVTLTGGGENVT
                     KELKDKFTSGDFTVVIKYNQSSEKGLQALFGISNSKPGQQNSYVDVFLRDNGELGMEA
                     RDTSSNKNNLVSRPASVWGKYKQEAVTNTVAVVADSVKKTYSLYANGTKVVEKKVDNF
                     LNIKDIKGIDYYMLGGVKRAGKTAFGFNGTLENIKFFNSALDEETVKKMTTNAVTGHL
                     IYTANDTTGSNYFRIPVLYTFSNGRVFSSIDARYGGTHDFLNKINIATSYSDDNGKTW
                     TKPKLTLAFDDFAPVPLEWPREVGGRDLQISGGATYIDSVIVEKKNKQVLMFADVMPA
                     GVSFREATRKDSGYKQIDGNYYLKLRKQGDTDYNYTIRENGTVYDDRTNRPTEFSVDK
                     NFGIKQNGNYLTVEQYSVSFENNKKTEYRNGTKVHMNIFYKDALFKVVPTNYIAYISS
                     NDHGESWSAPTLLPPIMGLNRNAPYLGPGRGIIESSTGRILIPSYTGKESAFIYSDDN
                     GASWKVKVVPLPSSWSAEAQFVELSPGVIQAYMRTNNGKIAYLTSKDAGTTWSAPEYL
                     KFVSNPSYGTQLSIINYSQLIDGKKAVILSTPNSTNGRKHGQIWIGLINDDNTIDWRY
                     HHDVDYSNYGYSYSTLTELPNHEIGLMFEKFDSWSRNELHMKNVVPYITFKIEDLKKN
                     "
     gene            6798..7907
                     /locus_tag="VYO11_001770"
     CDS             6798..7907
                     /locus_tag="VYO11_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEV1596289.1"
                     /translation="MVNYGIVGAGYFGADLARSMNKIEDAKVVAVFDPNHGEEVAQEL
                     GSDVCASLDELVAREDIDCVIVASPSYLHREPVVKAAQHGKHVFCEKPIALSYEDCKA
                     MVDACKENNVIFMAGHIMNFFNGVHHAKELITQGKIGKVLYCHAARTGWEEQQPTVSW
                     KKLRSQSGGHLYHHIHELDCIQFIMGGLPEKATMVGGNVYHKGENFGDEDDMLIVNLE
                     YSDDRYAVLEYGNAFRWGEHYVLIQGTEGAIKLDLFNTGGTLRVKGEGESHFLVHETQ
                     EEDDDRTAIYTGRGMDGAIAYGKPGVRCPLWLQTCIDKEMEYLHDIIKGGEITEEFEK
                     LLNGVAALESIATADACTLSVKEDRKVSLSEITNA"
     gene            8064..8954
                     /locus_tag="VYO11_001771"
     CDS             8064..8954
                     /locus_tag="VYO11_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEV1596290.1"
                     /translation="MKIIGIDIGGTTIKADLYDEFGTSLNHFKEIETIIDYDLGTNQI
                     LNQVCDLIGEYTLNHSIDGVGISTAGVVNANTGEIIYAGYTIPGYIGVNFTAEIEKRF
                     GLYTFVENDVNCAALGELWKGQAKDKKNVVMVTIGTGIGGSIIVNGQIVNGFNYTAGE
                     VGYIPVGNSDWQSKASTTALIHLYQKKSLKTNQTGRTFFTDLRSGDKVAEETFEIFVE
                     NLTKGLLTISYLLNPEILILGGGILDSKDILLPEIQSSLAKNAMDNRFLPKNLVAATL
                     GNEAGRIGAVKNFLDRISNK"
     gene            8979..9302
                     /locus_tag="VYO11_001772"
     CDS             8979..9302
                     /locus_tag="VYO11_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1596291.1"
                     /translation="MTNSVFSTMQDIENVATDIIKSYDNEIYTYKAVSQEELEKLEKS
                     YDEKSHEELVSIESNLEMKQQNLIDEVNKTIKENDANIQYISSSRRGEFVEKIIGRVV
                     EKYGH"
     gene            9292..11283
                     /locus_tag="VYO11_001773"
     CDS             9292..11283
                     /locus_tag="VYO11_001773"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HEV1596292.1"
                     /translation="MAISQMKRISLLFSKSSLDDVLKTIQELESVQFRDLKVQDNWSE
                     ALEKDEVVFPTIQIFHTSNSNHGVIEGNDALTYLMNQQQHLEATVEKLQEYLPKENTF
                     KLLQQPPITTSYEELEKFGKANVAEGVLKKVNHQINRVHELERHIQSNNEEIERLIKW
                     EKLEIVPANLEQFSFCKGKVGTIPRTEDNRLYNSLLENNIEVQEIFSNDREYGVVVFY
                     QSSYSIDFDEYLFEPFDYSRKELPKQRVVDLDQENMQLITEKENIIASLQDSKKYLID
                     LQWQIDYILSIYARQISKNNFLCTPHLVALEGWIEETRILYFIKVMDEHFGHSIYIYE
                     SETLTDNQDEIPIKLTNHSLIEPFELLTEMYALPKYYEKDPTPVLAPFYFTFFGMMVA
                     DLGYGLLLFLGTMLALKIFHLPSATKRFLKFFNILGVAVAIWGGIYGSFFGYELPFHL
                     ISTTSDVMTILVVSVVFGFITVFAGLLASGLQKVRMKKYAEAYNSGFAWCVILLGLLF
                     IAVGMLMPDMRPLFVLGKWVSIFNAVGILIVSIIQTKSLSGIGAGLFNLYNISSYIGD
                     LVSFTRLMALGLSGASIASAFNLIVGLFPGILAKLTIGLVLFILLHAINIFLSLLSGY
                     VHGARLIFVEFFGKFYEGGGKPFQPLKASEKYIKVITKN"
     gene            11299..11775
                     /locus_tag="VYO11_001774"
     CDS             11299..11775
                     /locus_tag="VYO11_001774"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit K"
                     /protein_id="HEV1596293.1"
                     /translation="MEHLATYFSTYGGAFFAALGIVLAVGLSGMGSAYGVGKAGQSAA
                     ALLKEQPEKFASALILQLLPGTQGLYGFVIGILIWLQLTPELPLEKGVAYFFVALPIA
                     IVGYFSAKHQGNVAVAGMQILAKRPKEFMKGAILAAMVETYAILAFVVSFILTLRV"
     gene            11809..>12279
                     /locus_tag="VYO11_001775"
     CDS             11809..>12279
                     /locus_tag="VYO11_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000067169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1596294.1"
                     /translation="MSNLENLRESVIEQAHEKGRMKLLDSKKKIDDEFEMQKSLIIKK
                     KEAEHERKLKELQQKYQIIFQQLKNKERQSTLVSKQKILKELFQSALLEMESWSADKE
                     MEFIYRILERYSQQEVIVTFGERTLAKFNLEQLEKLKFSFPNYLFSEQPISNESG"
BASE COUNT         4157 a         1767 c         2432 g         3923 t
ORIGIN      
        1 gtaaacgttt acttcaacta aggagctcat atgttactgc aaaaagaact aattccaatg
       61 atagaagcta acttaccaaa tatggcatat gctgaaaaag acattgctaa attcttctta
      121 aaacagcaac ctctgaatga ttattcatct aaagcattgt gcgaatacct taatgtatcc
      181 aaagcaacat tgactcgatt tgcgaaaaaa tgtggtttta aaggttttag acaattcatt
      241 ttcaaatacc aagagatgat tcatgagaaa gaaaagttgg cattatatac agaggcaaca
      301 gaaaaagttt tatccgacta tgaggaaatg ttgagaaaaa cttacacggt tcttgatgaa
      361 gttcaacttg agcgtattgc tgagatgata gaaactgctg agcgtgtata tctctacggt
      421 aaaggaagtt ctgttcttgc tttacaagaa atgaagatga gatttatgcg tctcggagtg
      481 attggtgaag tattatcaga cgaggatatg attttgtgga gtagcttact acttaatgaa
      541 aattgccttg tcattggagc atccatttca ggtcaaactg atattgtact agaaggtcta
      601 caaaaagctg cagataaagg cgctaaaaca gttttaatga ctacaagaaa atttgacgaa
      661 gaagattgtt tctttgatga actattgtta ttagcttcga ccgatcatct ctcgtatggc
      721 aatcgcatat cacctcagtt tccaatactt ttaattacag actgcttatt ctctaattat
      781 ctggaaagtc cagagagaca atattattac aatcaaacta ttatccataa ggaggaataa
      841 taaaatgagc caaatttgga ctaaagaaaa atttataagc caagttcaag gtggagtcat
      901 tgtttcttgt caagctttac ctggtgaagc cctttataat gaagaattta gcttgatgcc
      961 ttttatggct aaagcagctt tagaggcagg agcagtgggc attcgcgcaa attctgtgcg
     1021 tgatattaaa gcaattcaga aagtagtaga tttaccaata attggaatta tcaaaaggga
     1081 ttatccacct caagaaccat atattactgc tacgatgaaa gaagtagatg aacttgtaga
     1141 atgcggaaca acagtcattg catttgatgc aactttaaga ccaagatatg atggcttagt
     1201 tgtcagtgaa tttatcaaaa aaataaaaga aaaatatccg aatcaattgc tgatggcgga
     1261 tgtaagtaat ttagatgaag gtctctatgc atttaaatca ggcgttgatt ttgttggtac
     1321 aacattatca ggttacacaa gtacaagtgt acaatcagat gagcctgatt ttgaactaat
     1381 gaaaaaattg gctgatttta atattccggt aattgccgaa ggaaaaattc attatccaga
     1441 acaattaaaa aaagcttata gtttaggtgt taccagtgta gtcattggtg gagcgattac
     1501 acgtccaaaa gaaattgctc agcgatttat taatgtcatc aaataaaaaa caatataaag
     1561 gagaaatctg atgaaagatt taactaaata caaaggcgtt atccctgcat tttatgcttg
     1621 ctatgatgaa aatggtgaaa ttagccaaga tcgtgtaaaa tctctggtac aatatttcat
     1681 tgacaaaggt gtaaaaggta tctatgtaaa tggttcttca ggtgaatgta tttaccaaag
     1741 tgtagaagat cgtaaacaaa ttattgaagc tgttatggaa gttgctaaag gtaaattaac
     1801 agttatcaac catattgcat gtaataacac gaaagatagt atcgaattgg caaaacattc
     1861 agaaagtgtt ggagtcgatg ctattgcagc tatcccacct atttatttca aattgccaga
     1921 gtattcaatc gcagcatatt ggaatgcaat gagtgaagct gcgtcaaata cagattttat
     1981 tatctataat attccacaat tggcaggggt tgcgttgact ggtagtttgt atgcaacaat
     2041 gcgtcaaaat cctcgtgtga ttggagttaa aaattcttct atgcctgtac aagatattca
     2101 aatgtttgta gctgcaggtg gagaagatta cattgtattc aatggtccag atgaacaata
     2161 tcttggtggt cgcttgatgg gagcagaagc tggtattggt ggtacttatg gcgttatgcc
     2221 agatttgttc ttgaaattgg aaagtttgat tcaagaacga gatttagata cagctaaaaa
     2281 acttcaatat gctatcaatg aagttatcta taagatgata tcaggtaagg caaatatgta
     2341 tgctgtagca aaagaagttt tgcgtctaaa tgaaaaactt gatttaggtt ctgttcgtca
     2401 acctttagaa gcattggcag aaggtgactt ggaagttgca aaacaagcag cagaacttat
     2461 tcaacaagca cgaaaagaat ttttataata aataaaatca atatggagat atgttatggg
     2521 cacaacagga tttacaataa ttgacttaat tatcttgatt gtttatttac ttgcggtgtt
     2581 ggttgcaggt atctatttct ctaaaaaaga gatgaaagga aaagagttct ttaaaggaga
     2641 tggttcggtt ccttggtatg ttacttcggt atccattttt gccacaatgc tcagtccgat
     2701 ttccttcttg ggactcgctg gtagctctta tgcaggtagc tggattttat ggtttgctca
     2761 attagggatg gtagtagcta ttccactgac aattcgtttt atcttaccta tctttgcacg
     2821 gatagacatc gatacggcat atgattactt ggataaacgt tttaattcta aagcacttcg
     2881 tattatttca gcactcttgt ttattattta tcaattggga cgtatgtcta tcattatgta
     2941 cctcccatca gctggtttat cagtattgac aggaattgac atcaatattt tgattatttt
     3001 gatgggtgta gttgcaattg tttattctta tactggtggt ctaaaatccg tattatggac
     3061 agactttatt caaggtgtga ttctgattag tggtgtcgtt ttagctttat ttgtactgat
     3121 tgctaatatt aaaggtggct ttggtgcagt agcagaaaca ttagcaaacg ggaaattcct
     3181 tgctgcaaat gaaaaacttt tcgatcctaa cttgctttca aactccatct ttttaattgt
     3241 gatgggttca ggctttacaa tcttgtcttc ctatgcttca tctcaagatt tggttcaacg
     3301 ttttactaca acacaaaata ttaagaaact taataagatg ttgttcacaa acggtgtttt
     3361 gtcacttgca actgcaacag tcttttactt gattggtaca ggcttgtacg tattctatca
     3421 agtacaaaat gcagatagtg cagctagcaa tatccctcaa gaccaaatct ttatgtactt
     3481 tattgcatac cagttaccag taggtatcac aggtttgatc ttggcagcga tttatgcagc
     3541 atctcaatca actatttcaa caggtttgaa ctctgttgca acttcatgga cattggatat
     3601 tcaagatgtc atttctaaaa atatgtcaga caatcgtcgt acgaaaattg cacaattcgt
     3661 atctctagca gtaggtttat tctcaattgg tgtttccatt gtcatggctc actcagatat
     3721 taaatctgca tacgaatggt tcaatagttt catgggactt gtacttggtc tacttggtgg
     3781 tgtatttatt cttggatttg tttctaaaaa agcaaataaa caaggtgctt atgcagcgct
     3841 gattgtatca accatcgtca tggtatttat taaatacttc cttcctccaa cagctgttag
     3901 ctactgggca tattcattga tttcaatctc tgtatcagta gtttcaggtt atattgtatc
     3961 tgttcttact ggaaataaag tatctgcacc taaatataca acgattcatg atattacaga
     4021 aattaaagcg gattcaagtt gggaagttcg tcactaatag aaaagagaaa ataatatgat
     4081 tatttctgaa caatctgatt ttaaacgata tgcttctgtc aataaatatt tttcaaaagt
     4141 ctgtgatttt ttagaaaata caaatttgac agatttagtt gatggaaaaa ttgatattga
     4201 cggggaaaat gtttttgcaa attgtatgac ttatctagct gatggagttc caggagatat
     4261 ttttgaaact cataagaaat atttagatat tcatattgtt gttgaaaata ctgaaaaaat
     4321 ggcagtaact tccccagttc gtgcccagtc acgtgtacct tttagcgaag agaaggatat
     4381 tgctttttac gatagcaaag actatcaaat tgttgaattg cttccaggga atatgttggt
     4441 gacttttgaa gaagatcttc accaaccaaa gattcattgc aatgatgaaa cggttaaaaa
     4501 acttgttatc aaagttttaa acgaggaaaa ataaaatgaa aaaaaatatt aaacaatatg
     4561 taaccttagg tactgtagtg gtattatcag catttgttgc taactcagtt gcagctcagg
     4621 agactgaaac ttctgaagta tcaacaccaa agttggtgca acctgttgca ccaacgactc
     4681 cgatttcgga agtacaacct acatcggata actcttcgga agttactgta caacctcgaa
     4741 cagttgaaac tactgttaag gatccatctt ctacagcgga agaaactcct gtcttagaaa
     4801 aaaataatgt tactttaaca gggggcggag aaaatgttac taaagagtta aaggataaat
     4861 ttactagcgg tgactttact gtagtgatta agtacaatca gtcaagtgag aaaggcttac
     4921 aagctctgtt tggaatatct aattccaaac ccggtcaaca aaatagttat gtagatgtgt
     4981 tccttagaga caatggtgag ttggggatgg aagcgcgtga tacttcttcc aataaaaata
     5041 acctagtatc cagacctgct tcagtttggg gtaagtacaa acaagaggct gtgactaaca
     5101 ctgttgcagt agtagcagat tcagtcaaaa aaacatattc tttatacgca aatggtacaa
     5161 aagtagtaga aaagaaagtg gataatttcc taaacatcaa ggatattaaa ggtattgatt
     5221 actatatgct tgggggagtg aaacgtgcag gaaaaacggc gtttggtttt aacggaacac
     5281 tagaaaatat caaattcttt aatagtgcat tggatgaaga aactgttaaa aagatgacaa
     5341 caaacgctgt tactggacat ttaatttata cggctaatga tacaacaggt tctaactatt
     5401 tccgtattcc agttctgtat acttttagca atggtcgggt attttcaagc attgacgctc
     5461 gttacggtgg aactcatgat ttcttgaata aaattaatat tgctacaagt tatagtgatg
     5521 ataatggtaa gacatggact aaaccaaaat taacattggc attcgatgat tttgcgccag
     5581 taccattaga atggcctcgt gaagttggtg gacgtgactt acaaatcagc ggtggtgcaa
     5641 cctatattga ctctgttatt gttgaaaaaa agaacaaaca agtactcatg tttgctgatg
     5701 tgatgcctgc tggagtaagt tttagagaag caactagaaa agattcaggt tataaacaaa
     5761 ttgatggtaa ttattacctt aaattaagga aacaaggtga tactgattac aattatacta
     5821 ttcgtgagaa tggtactgta tacgacgatc gtaccaacag accaactgaa ttttcagtag
     5881 ataaaaattt cggtattaaa caaaatggta attatttgac ggtagagcaa tattcggttt
     5941 catttgaaaa taataaaaag actgaatatc gtaatgggac taaagtccat atgaatatct
     6001 tctacaaaga tgcattgttt aaagtagtgc caacgaacta tattgcatat atttctagca
     6061 atgatcatgg cgaatcttgg tctgcaccaa ctttattacc tcctataatg ggacttaatc
     6121 ggaatgcgcc atatttaggt cctggacgtg gaatcattga aagctcaact ggacgtattc
     6181 ttattccgtc ttacactggt aaagagtctg cgttcattta tagtgacgat aatggagcat
     6241 cttggaaagt taaagtagtg ccacttcctt ctagttggtc agcagaagca caatttgtag
     6301 aattgagtcc aggagtaatt caagcatata tgcgtacaaa taatggtaaa attgcatatt
     6361 taacaagtaa agacgcaggt actacttgga gtgcaccgga atatttgaaa tttgtttcaa
     6421 atccaagtta tggaacacaa ttatcaatca tcaattatag ccaattgatt gatggtaaaa
     6481 aggctgtcat tttaagtact ccaaactcca caaatggtcg taaacacgga caaatttgga
     6541 ttggtctaat taatgatgat aatacaattg attggcgtta tcatcacgac gttgattata
     6601 gtaactatgg atactcatat tcaacattga cagagttacc aaatcatgaa attggattga
     6661 tgtttgaaaa atttgattca tggtctcgta atgaacttca tatgaaaaat gttgtaccat
     6721 atataacatt taagattgaa gatctgaaaa agaattaaag ctgaaatttg aaaatatata
     6781 aaaagaggat aaaaattatg gtaaattacg gtattgttgg agctggatat tttggagctg
     6841 atttagctcg ctcaatgaac aaaattgaag atgcaaaagt ggttgcggta tttgacccaa
     6901 atcatggaga agaagttgct caagagttgg gatcagatgt ttgtgcaagt ttagatgaac
     6961 ttgtagcacg tgaagatatt gattgtgtga tcgtagcttc acctagctac cttcaccgtg
     7021 aaccagttgt gaaagctgct caacatggca aacacgtatt ttgtgaaaag ccaattgcat
     7081 tgtcttatga agattgtaaa gccatggttg acgcatgtaa agaaaataat gtcatcttta
     7141 tggctggtca catcatgaac ttctttaacg gtgtacacca tgctaaagaa ttgattactc
     7201 aaggtaaaat cggtaaagtt ctttattgcc atgctgctcg tacaggttgg gaagaacaac
     7261 aaccaactgt atcatggaag aaacttcgtt ctcaatctgg aggacatttg taccaccata
     7321 ttcatgaatt agattgcatt cagtttatca tgggaggact tcctgaaaaa gcgacaatgg
     7381 taggaggcaa tgtatatcat aaaggtgaaa actttggtga tgaagatgat atgctcattg
     7441 taaacttaga atactctgat gatcgttatg ctgttttgga atatggtaat gctttccgtt
     7501 ggggtgaaca ctacgtcttg attcaaggaa ctgaaggagc tatcaaactt gacttgttca
     7561 atactggcgg tactcttcgt gttaaaggtg aaggagaatc acacttctta gttcatgaaa
     7621 ctcaagagga agatgatgat cgtacagcta tctataccgg tcgtggtatg gatggagcaa
     7681 ttgcgtacgg taaaccagga gtacgttgcc cattatggtt gcaaacatgt attgataaag
     7741 aaatggaata tctacatgac attattaaag gtggagaaat tacagaagaa tttgaaaaac
     7801 ttctcaatgg tgtagctgct ttagaatcaa tcgctaccgc tgatgcatgt actttatcag
     7861 ttaaagaaga tcgaaaagta agtctttcag aaatcacaaa tgcttaactt ttgtaaaaca
     7921 gaatagtaaa ttcttgtcat tatataattt ctaaagttct gtgatacaac tcattgaata
     7981 aagaaataga gatgggactg ggataatgcc cagtcccatt ttttatcaaa aagtaatgag
     8041 atcaaaaatg tgggagtgtt gaaatgaaga ttataggtat cgatattggc ggaacaacaa
     8101 ttaaggcaga tttatacgat gagtttggaa cgagtttgaa tcatttcaaa gagatagaaa
     8161 caattattga ctatgatttg ggaacgaatc agatattaaa tcaggtctgt gatttaattg
     8221 gtgagtatac tttaaatcat tcaattgatg gtgttgggat ttccactgct ggagttgtta
     8281 atgctaatac tggagaaatc atctatgcag gctatacaat accagggtat atcggagtaa
     8341 actttactgc cgaaatagaa aaacgttttg ggttgtatac ttttgttgaa aatgatgtta
     8401 attgtgctgc attaggtgaa ttgtggaagg gacaagccaa agataagaaa aatgtagtaa
     8461 tggttactat tggaacaggt ataggaggca gtattattgt caacggacaa attgttaacg
     8521 gatttaacta tactgctggt gaagtaggtt atattcctgt aggtaattcg gattggcaaa
     8581 gtaaagcctc aacaaccgca ttgattcatt tatatcaaaa aaagagcttg aaaactaatc
     8641 aaactggacg tactttcttc actgatttaa gatctggaga taaagttgct gaagaaactt
     8701 ttgaaatttt tgtagaaaat ctaacaaaag gtttattaac gatttcttat ctacttaatc
     8761 cagaaattct catattagga ggtgggattc tggatagtaa ggatattttg ttacctgaaa
     8821 ttcaaagttc tttagctaaa aatgcaatgg ataataggtt tttacctaaa aatcttgtgg
     8881 cagctacatt aggaaatgaa gctggtcgta taggagctgt aaaaaatttc ttagatagaa
     8941 tttctaataa atagtatgta agataaggag gtgtcacaat gactaactct gtattttcga
     9001 caatgcaaga tattgagaat gttgcaaccg atattataaa atcatatgat aatgagattt
     9061 atacttataa agctgtttcc caagaagaat tggaaaaact agaaaaaagt tatgatgaaa
     9121 aaagtcacga agaattagtt tcaatagaaa gcaatttaga aatgaaacaa cagaacctta
     9181 ttgatgaggt taataaaaca atcaaggaaa atgatgcaaa tattcagtat atttcatcaa
     9241 gtaggagagg agaatttgta gaaaaaatta ttggtagggt ggtagaaaaa tatggccatt
     9301 agtcagatga aaagaatctc tctactattt tctaaaagta gtcttgatga tgttttaaaa
     9361 actattcaag aactagagtc agtgcagttc cgtgatttaa aggttcagga taattggtca
     9421 gaagctctag aaaaagatga agttgtattt ccaactattc aaatttttca tacttctaat
     9481 tccaatcatg gggttattga gggaaatgat gccttgactt atttgatgaa tcaacaacaa
     9541 catttagaag caactgtaga gaaattacaa gaatacctac cgaaagaaaa cacgtttaaa
     9601 ttattgcagc aacctccgat aactacctct tatgaagaat tagagaaatt tggtaaagct
     9661 aatgttgctg agggtgttct taaaaaagtg aatcatcaaa ttaacagagt tcatgaatta
     9721 gaaagacaca ttcaaagtaa taatgaggaa atagagcgat taataaagtg ggaaaaatta
     9781 gaaattgttc ctgcgaattt agaacaattt tctttctgta aaggaaaagt cggaacaatt
     9841 ccaaggactg aagataatcg cttatacaat agtcttttag aaaacaatat tgaagttcaa
     9901 gaaatatttt ctaatgatag agagtacggt gttgttgttt tctatcagtc tagttactct
     9961 atagattttg atgaatactt atttgaacca tttgattatt ctagaaagga attaccgaag
    10021 cagcgagtag tagatttaga tcaagaaaac atgcagttaa taactgaaaa agagaatatt
    10081 atcgcatcgt tgcaagattc aaagaaatat ttgatagatt tacaatggca aatagactat
    10141 attttatcta tctatgctcg tcaaatctct aagaataact ttttgtgcac tccgcatcta
    10201 gttgcattag aaggatggat agaagaaact cgtattttat attttataaa agttatggat
    10261 gagcattttg gacattctat ttatatttat gaatcggaaa cattgacgga taatcaagat
    10321 gaaataccta tcaaattaac gaatcattct ttaattgaac catttgaatt attgacagaa
    10381 atgtatgctc tgcccaaata ttatgagaaa gatcctacac ctgtattagc accattttac
    10441 tttacatttt ttggaatgat ggttgctgat ttaggctatg gtttactatt gtttttagga
    10501 acaatgttag cattaaaaat ttttcatcta ccttcagcaa ctaagagatt tttaaaattc
    10561 tttaatatat taggggtagc cgttgcaatt tggggtggaa tctatggctc attttttgga
    10621 tatgagttgc catttcatct gatatctaca acctctgatg ttatgactat attagtagtg
    10681 tcagttgtgt ttgggtttat tacagtattt gcaggtttgt tagcttcagg actacaaaaa
    10741 gtaagaatga agaaatatgc agaagcatat aattcaggat ttgcgtggtg tgttattctg
    10801 cttggcttgt tatttattgc tgttggaatg ttgatgcctg atatgagacc gttatttgta
    10861 ttagggaaat gggtatctat ttttaatgct gtggggattt tgattgtttc tattattcaa
    10921 accaaaagct tgtcaggtat tggagcagga ttgtttaatc tatataacat ttcatcttat
    10981 ataggtgatt tagttagttt cactcgattg atggcattag gattatctgg agcaagtata
    11041 gcatcagctt tcaatttaat tgttggtttg tttccgggaa tattggctaa actgacaatt
    11101 ggattagtat tattcattct tttacatgcg atcaatattt ttctatcgtt actatcagga
    11161 tatgttcatg gagcacgtct gatatttgtt gaattttttg gtaagtttta tgagggtgga
    11221 ggaaaaccat ttcaaccttt gaaggcttct gagaaatata ttaaggttat tacaaagaat
    11281 taatggagga tatatataat ggaacattta gcaacttatt tttcaaccta tggaggagct
    11341 ttcttcgctg cattgggaat tgtattggcg gttggattaa gcggtatggg gtctgcttat
    11401 ggagttggta aggctgggca atctgccgca gctttactga aagaacagcc tgaaaagttt
    11461 gcctcagctt tgatattgca attattgccc ggaacacaag gattatatgg ttttgttatt
    11521 ggaattttaa tttggttgca attaactcca gaacttcctt tagaaaaagg cgttgcttat
    11581 ttctttgtag ctcttccaat tgctattgta ggatactttt cagctaagca tcaaggaaat
    11641 gtagcagtag cgggaatgca aatcttggct aaaagaccaa aagaattcat gaagggagca
    11701 attttagctg ccatggtaga aacctatgca attcttgctt ttgtcgtatc attcattttg
    11761 acccttcgtg tataagaaat aaatttgcaa ttcaaaggag gtgtctaaat gagcaattta
    11821 gaaaacttac gagagtctgt tattgaacaa gctcatgaaa aagggcgtat gaaattattg
    11881 gattccaaaa agaagattga tgatgaattt gaaatgcaaa agtcgctcat tataaagaaa
    11941 aaagaagctg aacatgaacg aaagttaaaa gaattgcaac agaaatatca aataattttt
    12001 caacaattaa aaaataagga acgccaatca acgttagtat caaaacagaa aatattaaaa
    12061 gaactttttc aatctgcttt actagaaatg gaatcttgga gtgcagataa agaaatggag
    12121 ttcatctatc gaattctgga acgatattca caacaagagg tcatagtaac ctttggggaa
    12181 cggactttag ctaaattcaa tttggaacaa ttagagaaat tgaaattctc ttttccaaat
    12241 tatttattta gtgaacaacc tatctcaaat gaatcaggc
//
LOCUS       DAVLXH010000056        12076 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00028199
            SAMN33607166-rid17955573.denovo.056, whole genome shotgun sequence.
ACCESSION   DAVLXH010000056 DAVLXH010000000
VERSION     DAVLXH010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607166
            Sequence Read Archive: SRR23725544
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12076)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12076)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721421.1
            Genome Coverage       :: 115x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:42:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,210
            CDSs (total)                      :: 2,161
            Genes (coding)                    :: 2,023
            CDSs (with protein)               :: 2,023
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 73 of 138
            Pseudo Genes (incomplete)         :: 60 of 138
            Pseudo Genes (internal stop)      :: 40 of 138
            Pseudo Genes (multiple problems)  :: 31 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12076
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607166-rid17955573.denovo.056"
                     /strain="AUSMDU00028199"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1349"
     gene            545..2224
                     /locus_tag="VYO11_001776"
     CDS             545..2224
                     /locus_tag="VYO11_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000721501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-fucosidase"
                     /protein_id="HEV1596295.1"
                     /translation="MKKIKPHGPLPSQTQLAYLGDELAAFIHFGPNTFYDQEWGTGQE
                     DPERFNPSQLDAREWVRVLKETGFKKLILVVKHHDGFVLYPTAHTDYSVKVSPWRRGK
                     GDLLLEVSQAATEFDMDMGVYLSPWDAHSPLYHVDREADYNAYYLAQLKEILSNPNYG
                     NAGKFAEVWMDGARGEGAQKVNYEFEKWFETIRDLQGDCLIFSTEGTSIHWIGNERGH
                     AGDPLWQKMNPDKLGTEAELNYLQHGDPSGTIFSIGEADVSIRPGWFYHEDQDPKSLE
                     ELVEIYFHSVGRGTPLLLNIPPNQAGLFDAKDIERLYEFATYRNELYKEDLALGAEVS
                     GPALSADFACRHLTDGLETSSWASDADLPIQLELDLGSPKTFDVIELREDLKLGQRIA
                     AFHVQVEVDGVWQEFGRGFTVGHKRLLRGPLVEAQKVRVMITEAQSIPVLTKISLCKT
                     PGLSKKEVVQELAFAEKSLAVAKGETLHFRIERSESSSSLEAKISIQPGTGVHGVAYQ
                     DEIQVLQFQAGESKKDLHLPTLYFAGDKTLDFYLNLTVDGQLVDQLQVQVS"
     gene            complement(2264..4348)
                     /locus_tag="VYO11_001777"
     CDS             complement(2264..4348)
                     /locus_tag="VYO11_001777"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000803403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HEV1596296.1"
                     /translation="MKPLLETIDTRFGTASKHAFSRGNTLPYTGVPFGMNYFVPQTSD
                     QDGAWFFDPHLPIFQGIRLTHQPSPWIGDYSWLLLTPVTSQLGGDSLFHRQSSYDRDK
                     ASFQPHYLKIFSLRYQIETQLTPTCYGASIRLKQKQGKALSLYLHATDELTVEQVDKR
                     TLALRQEGKTETNKNSLTMFTALQMNTDILAISQEAGDWRIDLASSQTEMQLATSFIS
                     PSQALINLPQEDFDSCKTSAQADWENLLHRFDIIETGEADRTFFDHCLYRLFLFPQTF
                     YEVDESGQAIHMDLATGTVKPGVLFSNNGFWDTFRTTFPLFALIIPEHYQRFLEGFLN
                     SYRDTGFLPKWLAPDERGMMPGTLLDGIIADSACKDVAPDLEGKLFQAMLETASKADP
                     LGINGRHGLAQYQELGYLSTDHHESVSHTLDYAYSDFCIASCAKKLENIEIAETYKAA
                     SQNYRQLFDAETGYMRARDNQGNFHPDFSPYSWGRDYAECSAIQATLGVLHDIPGLIQ
                     LMGGKETFSNYLLKACQDAPLFETTGYGYEIHEMSEMATAPFGQIAISNQPSFHIPYL
                     FRYSDYPDYTALLIKTLRQKAFHPSWEAYPGDEDNGSLSAWYIWSALGFYPTCPGKPS
                     YDLGIPLFDHLRVYLAKEDKWLDIHTKQNHNHFNFVKECRLDKTLVSTIQHQDLLKAE
                     QLTFTLSWLPSH"
     gene            4519..5799
                     /locus_tag="VYO11_001778"
     CDS             4519..5799
                     /locus_tag="VYO11_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HEV1596297.1"
                     /translation="MIYSKEIVREWLDEVAERAKDHPEWVDVFERCYTDTLDNTVEIL
                     EDGSTFVLTGDIPAMWLRDSTAQLRPYLHVAKRDALLRQTIAGLVKRQMTLVLKDPYA
                     NSFNIEENWKGHHETDHTDLNGWIWERKYEVDSLCYPLQLAYLLWKETGETGQFDETF
                     VAATKEILHLWTVEQDHKNSPYRFVRDTDRKEDTLVNDGFGPDFAVTGMTWSAFRPSD
                     DCCQYSYLIPSNMFAVVVLGYVQEIFAALNLADSQSVIADTKRLQDEIQEGIENYAYT
                     TNSKGEKIYAFEVDGLGNASIMDDPNVPSLLAAPYLGYCSVDDEVYQATRRTILSSEN
                     PYFYQGEYASGLGSSHTFYRYIWPIALSIQGLTTRDKAEKKFLLDQLVACDGGTGVMH
                     ESFHVDDPTLYSREWFSWANMMFCELVLDYLDIR"
     gene            5890..8535
                     /locus_tag="VYO11_001779"
     CDS             5890..8535
                     /locus_tag="VYO11_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000432759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HEV1596298.1"
                     /translation="MENVVVHIISHSHWDREWYLPFESHRMQLVELFDNLFDLFENDP
                     EFKSFHLDGQTIVLDDYLQIRPENRDKVQRYIDEGKLKIGPFYILQDDYLISSEANVR
                     NTLIGQQEAAKWGKSTQIGYFPDTFGNMGQAPQILQKSGIHVAAFGRGVKPIGFDNQV
                     LEDEQFTSQFSEMYWQGVDGSRVLGILFANWYSNGNEIPVDKDEALTFWKQKLSDVRA
                     YASTNQWLMMNGCDHQPVQKNLSEAIRVANELFPDVIFVHSSFDEYVQAVEGALPEHL
                     STVTGELTSQETDGWYTLANTSSSRIYLKQAFQENSNLLEQVVEPLTIITGGHNHKDQ
                     LTYAWKTLLQNAPHDSICGCSVDEVHREMETRFAKVNQVGNFVKSNLLNEWKGKIATD
                     KAQSDYLFTVINTGLHDKVDTVSTVIDVATCDFKELHPTEGYKKMAALILPSYRVEDL
                     DGRPVEATIEDLGANFEYDLPKDKFRQARIARQVRVTIPVHLAPLSWTTFQLLEGKQE
                     HREGIYQNGVIDTPFVTVSVDDNITVYDKTTHEAYEDFIRFEDRGDIGNEYIYFQPKG
                     TEPIFAELKGHEVLENTDRYAKILLKHELTVPVSADEKLEEEQQGIIEFMKREAGRSE
                     ELTNIPLETELTVFVDNPQIRFKTRFTNTAKDHRIRLLVKTHNTRPSNDSESIYEVVT
                     RPNKPAASWENPENPQHQQAFVSLYDDEKGVTVSNKGLNEYEILGDNTIAVTILRASG
                     ELGDWGYFPTPEAQCLREFEVEFALECHQAQERFSAYRRAKALQTPFTSLQLARQEGS
                     VVATGSLLSHSVLSIPQVCPTAFKVAENEEGYVLRYYNMSQENVRISEHQQTILDLLE
                     RPYPVHSGLLAPQEIRTEFIKKEEI"
     gene            8618..9487
                     /locus_tag="VYO11_001780"
     CDS             8618..9487
                     /locus_tag="VYO11_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEV1596299.1"
                     /translation="MTIATIDIGGTGIKFASLTPDGKILDKTSISTPENLEDLLAWLD
                     QRLSEQDYSGIAMSVPGAVNQETGVIDGFSAVPYIRGFSWYEALSSYQLPVHLENDAN
                     CVGLSELLAHPELENAACVVIGTGIGGAMIINGRLHRGRHGLGGEFGYMTTLAPAGKL
                     NNWSQLASTGNMVRYVIEKSGHTDWDGRKIYQEAAAGNALCQEAIERMNCNLAQGLLN
                     IQYLIDPDVISLGGSISQNPDFIQGVKKAVDNFVDTYEEYTVAPVIQACTYHADANLY
                     GALVNWLQEEKQW"
     gene            9481..11361
                     /locus_tag="VYO11_001781"
     CDS             9481..11361
                     /locus_tag="VYO11_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HEV1596300.1"
                     /translation="MVRFTGLSPKQTQAIEVLKGHISLPDVEVAVTQSDQASISIQGE
                     EGHYQLTYRKPHQLYRALSLLVTVLAEADKVEIEEQAAYEDLAYMVDCSRNAVLNVAS
                     AKQMIEVLALMGYSTFELYMEDTYQIEGQPYFGYFRGAYSAEELQEIEAYAQQFDMTF
                     VPCIQTLAHLSAFVKWGVKEVQELRDVEDILLIGEEKVYDLIDGMFATLSKLKTRKVN
                     IGMDEAHLVGLGRYLILNGVVDRSLLMCQHLERVLDIADKYGFHCQMWSDMFFKLMSA
                     DGQYDRDVEIPEETRVYLDRLKDRVTLVYWDYYQDSEEKYNRNFRNHHKISHDLAFAG
                     GAWKWIGFTPHNHFSRLVAIEANKACRANQIKEVIVTGWGDNGGETAQFSILPSLQIW
                     AELSYRHDLDSLSAHFKTNTGLTVEDFMQIDLANLLPDLPGNLSGINPNRYVFYQDVL
                     CPILDRHMTPEQDKPHFAQAAETLANIKEKAGNYAYLFETQAQLNAILSSKVDVGRRI
                     RQAYQADDKESLQQIARQELPELRSQIEDFHALFSHQWLKENKVFGLDTVDIRMGGLL
                     QRIKRAESRIEVYLAGQLDRIDELEVEILPFTDFYADKDFAATTANQWHTIATASTIY
                     TT"
     gene            11652..12014
                     /locus_tag="VYO11_001782"
     CDS             11652..12014
                     /locus_tag="VYO11_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1596301.1"
                     /translation="MPKTKTLAELADVILWSFDFANDHAHAFFMDNIEWSHADSYFLS
                     FVSDDVEERYTENVYLDSLSVKQKFKFIFDFGDEWRFECQVLREIETEDEEAYLVRSV
                     GTSPEQYPDYDGFDYEEW"
BASE COUNT         3419 a         2463 c         2917 g         3277 t
ORIGIN      
        1 atttttttaa aaaatttttc aaaaaatata caaatgacca aaaagtgtcc aattatcatc
       61 tggttatcac ttggatctgt ataaagagaa atgtttgtgt gaaaggataa aaagatgcaa
      121 cattcttttg aagatagatt ttggagaagc atttcttgtt caattgtaca aattatagaa
      181 tcttttctga gtatttagga agagataatt atcttattga ccctcttttt attttttgtt
      241 atagtcgacg aggtgatagc ttagaataat cacttattca caatctgtgg aaaagtctgg
      301 atagtgaatg gtcttcacac aatgacctga aagaagcctg agaataatta tggagagtag
      361 cattctgaga ggtgttagca gaaccatatg acagagctgt ttgaagaggg aatattgagg
      421 agaaaaatcc tgagcctacc agttggagtt ggaaagagct gactgttaga tcatggttta
      481 ttatccacaa cctgtggata accttgtgaa taagagaagt tgctaaagaa ggagatatat
      541 aacgatgaag aaaatcaaac cgcatggacc gttaccaagt cagactcagc tagcttatct
      601 gggagatgaa ctagcagctt ttatccactt cggtcctaat accttttatg accaagaatg
      661 ggggactgga caggaggatc ctgagcgctt taacccgagt cagttggatg cgcgtgagtg
      721 ggttcgtgtg ctcaaggaaa cgggcttcaa aaagttgatt ttggtggtca agcaccacga
      781 tggctttgtc ctttatccga cagctcacac agattattcg gttaaggtca gtccttggag
      841 gagaggaaag ggcgacttgc tccttgaagt atcccaagct gccacagagt ttgatatgga
      901 tatgggggtc tacctgtcac cgtgggatgc ccatagtccc ctctatcatg tggaccgaga
      961 agcggactac aatgcctatt atctggctca gttgaaggaa atcttatcaa atcctaacta
     1021 tgggaatgct ggtaagttcg ctgaggtttg gatggatggt gccagaggag agggcgcgca
     1081 aaaggttaat tatgaatttg aaaaatggtt tgaaaccatt cgtgacttgc agggcgattg
     1141 tttgattttt tcaacagaag gcaccagtat ccactggatt ggcaatgaac gagggcatgc
     1201 aggtgatcca ctgtggcaaa agatgaatcc tgataaacta ggaacagaag cagagctgaa
     1261 ctatcttcag cacggggatc cctcgggcac gattttttcg atcggagagg cagatgtttc
     1321 catccgtcca ggctggttct accatgagga tcaggatcct aagtctctcg aggagttggt
     1381 cgaaatctac tttcactcag tagggcgagg aactccactc ttgcttaata ttccgccgaa
     1441 tcaagctggg ctctttgatg caaaggatat tgaacgactt tatgaatttg cgacctatcg
     1501 caatgagctc tataaagaag atttggctct gggagctgag gtatctggtc cagctctttc
     1561 cgcagacttt gcttgtcgcc atttgacaga cggccttgag accagctctt gggcaagcga
     1621 tgcagacttg cccatccagt tagaactcga tttaggttct cctaaaactt ttgatgtaat
     1681 tgagttaaga gaagatttga agctagggca acgaatcgct gcttttcatg tgcaagtaga
     1741 ggtggatggt gtctggcagg aatttggcag gggcttcaca gttggtcata agcgcctctt
     1801 gcgaggtccg ctagtagagg cacaaaaggt gcgcgtgatg attaccgagg cacaatctat
     1861 tcctgtattg accaagattt ccctttgtaa aactcctgga ttatcaaaaa aagaagttgt
     1921 tcaggaacta gcatttgcag aaaaaagcct agctgtggca aagggagaga ctcttcattt
     1981 taggattgaa cgtagtgaaa gtagctcctc tttagaggct aagatttcga ttcaaccggg
     2041 gacaggtgtc catggtgtcg cctatcagga tgagattcaa gtccttcaat tccaagcagg
     2101 ggaaagcaaa aaagatttgc atctaccaac cctgtatttc gcaggagata aaaccttgga
     2161 tttctatctg aacctaacgg tggatggtca gcttgtggat caacttcaag tccaagtttc
     2221 ataaaagaag aacctttgcg cgatgcaaag gttcttttgg ttattagtga cttggtaacc
     2281 agctgagggt gaaagttagt tgttcagctt ttaagaggtc ttggtgttga atagttgata
     2341 cgagtgtttt gtccagtcgg cattctttga caaagttaaa atggttgtgg ttttgtttag
     2401 tatggatatc cagccattta tcttctttag cgaggtagac tcgtagatgg tcaaagagag
     2461 ggattccgag gtcatagctt ggttttcctg gacaggttgg ataaaatccg agagctgacc
     2521 agatgtacca agcagagaga ctaccattgt cttcatctcc aggataggct tcccaacttg
     2581 ggtgaaaagc tttctgacgg agcgtcttga taagaagggc agtgtagtca gggtaatcgc
     2641 tgtagcggaa gagataagga atgtggaaac taggctggtt ggaaatggct atttgtccaa
     2701 aaggagcagt agccatctcg ctcatttcgt gaatttcgta accatagcct gttgtttcaa
     2761 agaggggagc atcttgacaa gctttcaaaa gatagttgct aaaggtttct tttccaccca
     2821 tcagttggat taagccaggg atgtcgtgga gaacgcctaa agtagcttga atggcagagc
     2881 attcagcgta gtctcgcccc caactataag gagagaagtc agggtgaaag tttccttgat
     2941 tgtctcgtgc tcgcatgtaa cctgtctcag cgtcaaatag ctggcggtaa ttttgtgaag
     3001 cagccttgta ggtttcagcg atttctatgt tctctagttt tttggcacag ctagcgatac
     3061 aaaagtcact ataggcatag tctagagtat ggctaacact ttcgtggtgg tcggtagaga
     3121 ggtaacctag ttcttggtat tgggctagtc cgtggcggcc attgattccg agagggtcgg
     3181 ctttgctggc tgtttcgagc atggcttgga agagttttcc ttctaggtca ggggccacgt
     3241 ccttgcaggc gctatctgcg ataataccgt ctaaaagtgt acctggcatc ataccccgtt
     3301 catctggagc cagccatttt ggaaggaaac cagtatcgcg gtagctattg aggaaacctt
     3361 ctaaaaagcg ttgatagtgc tccggtatga taagggcaaa gagggggaag gtggtgcgga
     3421 aggtatccca gaaaccattg ttgctaaaga ggacaccagg cttgacagta ccagtagcca
     3481 gatccatgtg gatggcttgc cctgactcat caacctcata aaaagtctgt gggaagagga
     3541 agagtctgta gaggcagtgg tcaaagaagg ttcggtcagc ctctcctgtc tctataatgt
     3601 caaaacgatg gaggagattt tcccaatccg cttgggcact tgttttacag ctatcaaaat
     3661 cttcttgagg tagattgatt agagcttgag aaggagagat gaaagaagtg gctagttgca
     3721 tctcggtttg actacttgct aagtcaattc gccagtcccc agcttcttgg ctgatagcaa
     3781 gaatatccgt gttcatttgc agggcagtaa acatcgttag cgaatttttg ttggtttcag
     3841 ttttaccttc ttgtcgcagg gcaagagttc gcttatctac ttgctctact gtcagttcat
     3901 ctgttgcgtg aagatagagg gagagggctt tgccttgctt ttgcttcaaa cgaatagaag
     3961 caccgtagca agtcggtgtg agctgggttt caatctgata gcgcagggag aaaatcttta
     4021 gataatgagg ttggaaagag gccttatccc tatcatagga agattggcgg tgaaagaggc
     4081 tgtctccacc cagttgactg gtgacgggtg tcagaaggag ccaagagtag tccccaatcc
     4141 aaggactggg ctggtgagtt aatcgaatcc cctgaaagat aggcagatgc ggatcaaaaa
     4201 accaagctcc atcctggtca ctggtctggg gcacaaagta attcattcca aaaggcacgc
     4261 ctgtgtatgg cagggtattt ccccgagaga aggcatgctt gctagcagta ccaaagcggg
     4321 tatcgatggt ttcaagtagt ggtttcatag tctttccttt agctgttttt ctacattata
     4381 tcagaaaaag agggccttta gaaaaggagt ttcaaaaata actattttgt agaaaaatga
     4441 ctatcatttg tgtatgtatt ttctgtctca aaagctatat actgaaaatg aaacttgttt
     4501 gaaagaggaa attgcacgat gatttattcg aaagaaattg ttagagaatg gctagatgaa
     4561 gtagcagagc gggctaagga ccatccagag tgggtggatg ttttcgagcg ttgctacacc
     4621 gataccttgg acaatacggt tgaaatctta gaagatggtt caacttttgt cttgactggg
     4681 gatattcctg ctatgtggct tcgggattcg acagcccaac tcagacccta ccttcatgta
     4741 gctaaaagag atgccctcct gcgtcagacc attgcaggtt tggtcaaacg tcagatgacc
     4801 ttggtactca aggatcctta tgccaattcc ttcaacatag aggaaaactg gaaggggcac
     4861 cacgagaccg accacaccga ccttaatggc tggatttggg aacgcaagta tgaggtggac
     4921 tcgctttgct atcctttgca gttggcttat ctcctctgga aagagactgg cgagactggt
     4981 cagtttgatg agacttttgt cgcagcgact aaggaaattc tccatctatg gacagttgaa
     5041 caagaccaca agaactctcc ttatcgtttt gtccgagata cggaccgtaa ggaagacacc
     5101 ttggtaaatg atggctttgg acctgacttt gcagtgacag gtatgacttg gtcagccttt
     5161 cgtccgagtg atgactgttg ccagtatagt tacttgattc cgtcaaatat gtttgctgta
     5221 gtagtcttgg gttatgtgca agaaatcttc gcagcattaa acctagctga tagccagagt
     5281 gttattgctg ataccaagcg tcttcaggat gaaatccaag aaggaatcga aaactacgct
     5341 tacaccacca acagcaaggg cgaaaagatt tacgcttttg aagtggatgg cctaggaaat
     5401 gccagcatca tggatgatcc aaatgtacca agtctactag ctgcgcccta tctgggctac
     5461 tgttcggtcg atgatgaagt gtatcaagct actcgtcgta ccattttgag ctctgaaaat
     5521 ccatacttct accaaggaga atacgctagc ggtctcggaa gttctcatac cttctatcgc
     5581 tatatctggc caatcgccct ttctatccaa ggattgacaa caagagataa ggcagagaaa
     5641 aaattcttgc tggatcagct ggttgcctgc gatggtggta caggtgtcat gcacgaaagc
     5701 ttccacgtag atgatccgac cctctactct cgtgaatggt tctcctgggc taacatgatg
     5761 ttctgtgagt tggtcttgga ttacttggat attcgctaag gggctcgctt tagctcaacc
     5821 gattcttatc agaatcacaa gtttacattt aaaacgttaa aatttaaatt tagaatgagg
     5881 ttttacttca tggaaaatgt tgttgtacat attatctcac atagtcactg ggaccgtgag
     5941 tggtacttgc cttttgaaag ccatcgtatg cagttggtgg aattgtttga caatctcttt
     6001 gatctctttg aaaatgaccc tgagttcaag agtttccact tggatggaca aactattgtc
     6061 cttgacgact acttacaaat tcgccctgaa aatcgtgaca aggtccaacg ctacattgac
     6121 gagggcaaac ttaaaattgg tcccttttac atcttgcagg atgactactt gatctccagt
     6181 gaagccaatg tccgcaatac cttgattggt caacaagaag ctgccaaatg gggtaaatca
     6241 acccagattg gctactttcc agataccttt ggaaatatgg gacaagcgcc tcaaattctt
     6301 caaaaatcag gcattcacgt ggcggccttt ggtcgtggtg tgaagccgat tggatttgac
     6361 aaccaagtcc ttgaagatga gcagtttaca tcccagtttt cagaaatgta ctggcagggt
     6421 gtggatggta gtcgtgtttt aggtattctc tttgccaact ggtacagtaa tgggaatgaa
     6481 atcccagttg acaaagatga ggccttgacc ttctggaaac aaaaattgtc agatgtgcgt
     6541 gcctacgctt cgaccaacca atggttgatg atgaacggct gtgaccacca gcctgtccag
     6601 aaaaatctga gcgaagccat tcgtgtggca aatgaactct tcccggatgt aatctttgtt
     6661 catagttctt ttgatgaata tgttcaagct gtagaaggtg cgcttcctga acacttatca
     6721 actgttacag gtgagttgac cagtcaggaa acagatggct ggtacacact tgccaacact
     6781 tcttcatccc gcatttacct aaaacaagcc ttccaagaaa atagcaacct cctagagcaa
     6841 gtggtagaac ccttgactat tatcactggt ggacacaacc acaaggacca gttgacctat
     6901 gcttggaaaa cacttttgca gaatgcgcca catgatagta tctgtggctg tagcgtggac
     6961 gaagttcacc gcgagatgga aacgcgtttt gccaaggtca accaagtagg aaactttgtt
     7021 aaaagtaatt tgctcaatga gtggaagggt aaaattgcta cggataaggc tcaaagtgac
     7081 tatctcttta ctgtcattaa cacaggcttg catgataagg tcgatactgt cagcacagtg
     7141 attgatgtgg cgacttgtga tttcaaggaa ttgcacccaa cagaaggcta caaaaagatg
     7201 gctgctctta tcttgccaag ttaccgtgtg gaggacttgg atggtcgtcc tgtagaggct
     7261 acaatcgaag acctcggagc taattttgaa tacgatttac caaaagataa gttccgccaa
     7321 gctcgtattg ctcgacaagt gcgtgtgacc attccagttc acctagcacc gctttcttgg
     7381 acaaccttcc aattgctgga aggaaaacaa gaacaccgtg agggtattta ccaaaacgga
     7441 gtgattgata caccattcgt aacggtgagt gtggatgaca acatcacagt ctatgacaag
     7501 acaactcacg aagcctatga agactttatc cgctttgaag accggggtga catcggaaac
     7561 gagtatatct atttccaacc aaaaggaaca gagccaatct ttgcagagct taagggccac
     7621 gaggtattgg aaaacacaga tcgctatgct aaaatcttgc tcaaacatga attgaccgtg
     7681 cctgtcagtg cggatgaaaa gctagaagaa gagcaacaag gtatcatcga gtttatgaag
     7741 cgtgaggctg gacggtcaga agaattgaca aacattcctc tggaaactga gttgactgtc
     7801 ttcgttgaca atccacaaat ccgcttcaag actcgcttta ctaacactgc caaggatcac
     7861 cgtatccgtc tcttggtcaa gactcataac acgcgtccaa gcaatgattc tgaaagtatc
     7921 tatgaggtgg tgacacgacc aaacaaacca gctgcttcat gggaaaatcc tgaaaatcct
     7981 caacaccaac aagcttttgt cagtctgtat gacgatgaaa aaggggtgac tgtatccaac
     8041 aagggattga atgaatacga aatccttggg gataacacca ttgccgtgac cattttgcgt
     8101 gcatcaggtg agctaggtga ctggggctac ttcccaacgc cagaagcaca atgcttgcgt
     8161 gagtttgaag tcgagtttgc acttgaatgc caccaagccc aagaacgctt ctcagcctat
     8221 cgtcgtgcca aagccttgca gacaccgttt accagccttc agcttgctag acaggaagga
     8281 agcgtggttg cgactggtag cctcttgagc cattctgttc tcagcatacc gcaagtttgt
     8341 ccaacagcct ttaaagtggc ggaaaatgaa gaaggctatg tccttcgtta ctataatatg
     8401 agtcaagaaa atgtgcgcat atcagaacat caacaaacca ttcttgactt acttgagcga
     8461 ccatatccag ttcattcagg actattggct ccacaagaga ttcgtacaga attcatcaaa
     8521 aaagaagaaa tttaatttca aaaagtaaac atcaaaagaa aggaggggcg aaaaagtaag
     8581 aactaactgc tgattcgcct cttttatggt aaaaacaatg accattgcaa cgattgatat
     8641 cggagggact gggattaagt ttgccagtct gactcctgat gggaaaatac tggataagac
     8701 aagtatttca acgcctgaaa acttggagga tttactagcg tggctagatc aacgcttgtc
     8761 agaacaggat tacagtggga ttgctatgag cgttccaggt gcagtcaatc aagagacagg
     8821 tgtgattgat ggcttcagtg cggtgcccta catccgtggc ttttcttggt atgaggctct
     8881 tagctcttat cagctacctg tccatttaga aaatgatgcc aactgcgttg gactcagtga
     8941 actactagct catccagagc ttgaaaatgc agcctgtgtc gtgattggga cagggattgg
     9001 cggagccatg attatcaatg gtagacttca tcgaggtcgc cacggtctgg gtggagaatt
     9061 tggctacatg acaacccttg cccctgctgg aaaacttaat aactggtcgc aactagcatc
     9121 aactgggaat atggtacgat acgtaattga aaaatctggt catactgatt gggacggtcg
     9181 caagatttac caagaggccg cagctggtaa tgctctttgt caagaagcca ttgagcgcat
     9241 gaactgcaat ctggcgcaag gcttgctcaa tatccagtat ctgatcgatc cagatgtcat
     9301 cagtctgggt ggctctatca gtcaaaatcc agattttatc caaggtgtca agaaggctgt
     9361 tgataacttt gtcgatacct acgaagaata cacggtcgcc ccagttatcc aggcctgcac
     9421 ctatcacgca gatgcaaatc tctacggtgc ccttgtcaac tggctacagg aggaaaagca
     9481 atggtaagat ttacaggact tagtcccaaa caaacgcaag ctattgaggt tttaaaaggt
     9541 cacatttctc taccagatgt ggaagtggct gtcactcagt ctgaccaagc ctctatctct
     9601 atccagggtg aggaaggtca ctatcaattg acctaccgca aacctcacca actttatcgt
     9661 gccttatcct tgttggtaac agttctagca gaagctgata aagtagagat tgaggaacaa
     9721 gcagcttacg aagatttggc ttacatggtt gactgttctc gaaatgcggt gctgaatgtg
     9781 gcttctgcca agcagatgat tgaggtcttg gctctcatgg gctactcaac ctttgagctt
     9841 tacatggaag acacttacca gattgaagga cagccttact ttggctattt ccgtggagct
     9901 tattcagcag aggagttgca ggaaatcgaa gcctatgctc aacagtttga catgaccttt
     9961 gtaccatgca tccagacctt ggcccacttg tcggcctttg tcaaatgggg tgtcaaggaa
    10021 gtgcaggagc tccgtgatgt agaggacatt cttctcattg gcgaagaaaa ggtttatgac
    10081 ctgattgatg gcatgtttgc cacgttgtct aaactgaaga ctcgcaaggt caatatcggg
    10141 atggacgaag cccacttggt tggtttggga cgctacctga ttttgaacgg tgttgtggat
    10201 cgtagtctcc tcatgtgcca acacttggag cgcgtgctgg atattgctga caaatatggt
    10261 ttccactgcc agatgtggag tgatatgttc ttcaaactca tgtcagcgga tggccagtac
    10321 gaccgtgatg tggaaattcc agaggaaact cgtgtctacc tagaccgtct caaagaccgt
    10381 gtgactctgg tttactggga ttattatcag gatagcgagg aaaaatacaa ccgtaatttc
    10441 cgcaatcatc acaagattag ccatgacctt gcatttgcag ggggagcttg gaagtggatt
    10501 ggctttacac ctcacaacca ttttagccgt ctagtggcta tcgaggctaa taaagcctgc
    10561 cgtgccaatc agattaaaga agtcatcgta acgggttggg gagacaatgg gggtgaaact
    10621 gcccagttct ctatcctacc aagcttgcaa atctgggcag aactcagcta tcgccatgac
    10681 ctagatagtt tgtctgcgca cttcaagacc aatactggtc taacggttga ggattttatg
    10741 cagattgacc ttgccaacct cttaccagac ctaccaggca atctcagtgg catcaatccc
    10801 aaccgatatg tcttttatca ggatgttctt tgtccgatac ttgaccgaca catgacacct
    10861 gaacaggaca aaccgcactt cgctcaggct gctgagacgc ttgctaacat taaagaaaaa
    10921 gctggaaact atgcttatct ctttgaaact caggcccagt tgaatgctat tttaagtagc
    10981 aaagtagatg tgggacgacg cattcgtcag gcctaccaag cggatgataa agaaagttta
    11041 caacaaatcg ccagacaaga attaccagaa cttagaagcc aaattgaaga cttccatgcc
    11101 ctctttagtc accaatggct gaaagaaaac aaggtctttg gtttggatac agttgacatc
    11161 cgtatgggcg gactcttgca acgcatcaaa cgagcagaaa gccgtatcga ggtttatctg
    11221 gctggccagc ttgaccgcat cgacgagctg gaagttgaaa tcctaccatt tactgacttc
    11281 tacgcagaca aggatttcgc agcaactaca gctaaccagt ggcataccat tgcgacagct
    11341 tcgacgattt atacgactta atactcttcg aaaatctctt caaaccacgt cagcttccat
    11401 ctacaacctc aaaacagtgt tttgagcagc ctgcagctag cttcctagtt tgctctttga
    11461 ttttcattga gtataaaaac aagaacacct tgcttggcgc agggtgtttc gcgtgaaaca
    11521 gaagaattat ctggtttcaa atgctacagt taaaattagt aaaacaagaa atagaagctg
    11581 aaaagccagc atctgtagag gcttggatca tttccgtcaa atttaaaaaa ggttgctacc
    11641 gacatatata gattccaaaa acaaaaacgt tagcggaact agcagatgtg attttatgga
    11701 gttttgattt tgcaaatgat catgctcacg catttttcat ggataatatt gagtggagtc
    11761 atgcagattc ttactttctt agctttgtta gtgacgatgt tgaagaacgt tacacagaaa
    11821 atgtctatct ggatagccta agtgtcaaac aaaaatttaa gtttattttc gacttcggtg
    11881 atgaatggcg ttttgaatgc caagtgctga gagaaatcga gacagaggac gaagaagctt
    11941 atctcgtacg ttcggttgga acgtcgccag aacaatatcc agattatgat ggttttgact
    12001 atgaagaatg gtaaaattga aatcagtctg tgtaggctta gtatttcaat agacttcctg
    12061 caaaactaga atccta
//
LOCUS       DAVLXH010000057        11830 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00028199
            SAMN33607166-rid17955573.denovo.057, whole genome shotgun sequence.
ACCESSION   DAVLXH010000057 DAVLXH010000000
VERSION     DAVLXH010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607166
            Sequence Read Archive: SRR23725544
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11830)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11830)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721421.1
            Genome Coverage       :: 115x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:42:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,210
            CDSs (total)                      :: 2,161
            Genes (coding)                    :: 2,023
            CDSs (with protein)               :: 2,023
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 73 of 138
            Pseudo Genes (incomplete)         :: 60 of 138
            Pseudo Genes (internal stop)      :: 40 of 138
            Pseudo Genes (multiple problems)  :: 31 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11830
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607166-rid17955573.denovo.057"
                     /strain="AUSMDU00028199"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1349"
     gene            1..456
                     /locus_tag="VYO11_001783"
                     /pseudo
     CDS             1..456
                     /locus_tag="VYO11_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000476106.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsK"
     gene            416..1597
                     /locus_tag="VYO11_001784"
                     /pseudo
     CDS             416..1597
                     /locus_tag="VYO11_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014678337.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
     gene            complement(1860..2252)
                     /gene="rpsI"
                     /locus_tag="VYO11_001785"
     CDS             complement(1860..2252)
                     /gene="rpsI"
                     /locus_tag="VYO11_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HEV1596302.1"
                     /translation="MSQAQYAGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     RLVINQPFAVTSTVGSYDVFVNVVGGGYAGQSGAIRHGIARALLQVDPDFRDSLKRAG
                     LLTRDSRKVERKKPGLKKARKASQFSKR"
     gene            complement(2272..2718)
                     /gene="rplM"
                     /locus_tag="VYO11_001786"
     CDS             complement(2272..2718)
                     /gene="rplM"
                     /locus_tag="VYO11_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HEV1596303.1"
                     /translation="MNKTTFMAKPGQVERKWYVVDATDVPLGRLSAVVASVLRGKNKP
                     TFTPHTDTGDFVIVINAEKVKLTGKKATDKIYYTHSNHPGGLKQISAGELRSKNAVRL
                     IEKSVKGMLPHNTLGRAQGMKLKVFVGAEHTHAAQQPEVLDISGLI"
     gene            3074..3391
                     /locus_tag="VYO11_001787"
     CDS             3074..3391
                     /locus_tag="VYO11_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HEV1596304.1"
                     /translation="MAFTNTHMRSASFGIVTSLPDDIIDSFWYIIDHFLKNVFELEEE
                     LEFQLLNNQGKITFHFSSQHLPTAIDFDFNHPFDPRYPPRVLVLDMDGRETILLPEEN
                     DLF"
     gene            complement(3436..4248)
                     /gene="folK"
                     /locus_tag="VYO11_001788"
     CDS             complement(3436..4248)
                     /gene="folK"
                     /locus_tag="VYO11_001788"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HEV1596305.1"
                     /translation="MDQLQIKDLEMFAYHGLFPSEKELGQKFVVSAILSYDMTKAATD
                     LDLTASVHYGELCQQWTTWFQETSEDLIETVAYKLVERTFESYPLVQEMKLELKKPWA
                     PVHLSLDTCSVTIHRRKQRAFIALGSNMGDKQVNLKQAIDKLRARGIHILKESSVLET
                     EPWGGVEQDSFANQVVEVETWLPAQDLLETLLAIESELGRVREVHWGPRLIDLDLLFV
                     EDQILYTDDLILPHPYIAERLFVLESLQEIAPHFIHPILKQPIRNLYDALKK"
     gene            complement(4291..4845)
                     /gene="folE"
                     /locus_tag="VYO11_001789"
     CDS             complement(4291..4845)
                     /gene="folE"
                     /locus_tag="VYO11_001789"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HEV1596306.1"
                     /translation="MDTQKIEAAVKMIIEAVGENVNREGLQETPARVARMYQEIFSGL
                     GQTAEEHLSKSFEIIDDNMVVEKDIFFHTMCEHHFLPFYGRAHIAYIPDGRVAGLSKL
                     ARTVEVYSKKPQIQERLNIEVADALMDYLGAKGAFVVIEAEHMCMSMRGVRKPGTATL
                     TTVARGLFETDKDLRDQAYRLMGL"
     gene            complement(4826..6148)
                     /locus_tag="VYO11_001790"
     CDS             complement(4826..6148)
                     /locus_tag="VYO11_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000658404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HEV1596307.1"
                     /translation="MKEIENNQWIANYRTDQPHFGLERMMELLALRGNPHLKLKVIHI
                     GGTNGKGSTIAFLKNLLEKLGLRVGVFSSPYLIHYTDQISINGESIPEARLETLMADY
                     QSLLEGEAVANLQGTTEFEIITALAYDYFASEQVDVAIMEVGMGGLLDSTNVCQPILT
                     GITTIGLDHVALLGDTLEVIAEQKAGIIKQGMPLVTGRIAPEALTVIDRIAEGKDAPR
                     LAYGTDYQVRHQESVVTGEVFDYTSAVRQGRFQTSLLGLYQIENAGMAIALLDTFCQE
                     DGRELASNDFLGQALEETSWPGRLEIVSRDPLMILDGAHNPHAIKALLVTLQERFADH
                     HKEILFTCIKTKALEDMLDLLGAMPDTELTLTHFADSRATDESVLKEAAKSRNLSYQD
                     WHDFLDQNLTDKKEEKQTVRIVTGSLYFLSQVRAYLMERKNENGYTKD"
     gene            complement(6150..7130)
                     /gene="folP"
                     /locus_tag="VYO11_001791"
     CDS             complement(6150..7130)
                     /gene="folP"
                     /locus_tag="VYO11_001791"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HEV1596308.1"
                     /translation="MVKSLEGVTDMSSKANHAKTAICGIINVTPDSFSDGGQFFALEQ
                     ALQQARKLIAEGASMLDIGGESTRPRPGSSYVEIEEEIQRVVPVIKAIRKESDVLISI
                     DTWKSQVAEAALAAGANLVNDITGLMGDEKMAHVVAKAGAKVVIMFNPVMARPQHPSS
                     LIFPHFGFGQAFTEEELADFETLPIEDLMEAFFDRALSRANQAGIAQENILLDPGIGF
                     GLTKKENLLLLRDLDRLHQKGYPIFLGVSRKRFVINILEESGFEVNPETELGFRNRDT
                     ASAHVTSIAARQGVEVVRVHDVASHRMAVEIASTIRLADEAENLDLKQYK"
     gene            complement(7224..7931)
                     /locus_tag="VYO11_001792"
     CDS             complement(7224..7931)
                     /locus_tag="VYO11_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV1596309.1"
                     /translation="MKEKNMWKELLNRAGWILVFLLAVLLYQVPLVVTSILTLKEVAL
                     LQSGLIVAGLSIVVLALFIFGARKTQLASFNFSFFRAKDLARLGLSYLVIICSNILGS
                     ILLQLSNETTTANQSQINDMVQNSSLISSFFLLALLAPICEEILCRGIVPKKIFRGKE
                     NLGFVVGTIVFALLHQPSNLPSLLIYGVMSIVLSWTAYKTQRLEMSILLHMIVNGVVF
                     CLLALVVIMSRTLGISV"
     gene            complement(7984..9402)
                     /locus_tag="VYO11_001793"
     CDS             complement(7984..9402)
                     /locus_tag="VYO11_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HEV1596310.1"
                     /translation="MDKLFKLKENGTDVRTEVLAGLTTFFAMSYILFVNPQILSQTGM
                     PAQGVFLATIIGAVAGTLMMAFYANLPYAQAPGMGLNAFFTFTVVFGLGYSWQEALAM
                     VFICGIISLIITLTNVRKMIIESIPNALRSAISAGIGVFLAYVGIKNAGLLKFTIDPG
                     NYTVVGEGADKAQATIAANSSAVPGLVSFNNPAVLVALAGLAITIFFVIKGIKGGIIL
                     SILTTTVLAIAVGLVDLSSIDFANNHVGAAFEDLKTIFGAALGSEGLGALVSDTARLP
                     ETLMAILAFSLTDIFDTIGTLIGTGEKVGIVATNGENHQSAKLDKALYSDLIGTTVGA
                     IAGTSNVTTYVESAAGIGAGGRTGLTALVVAICFAISSFFSPLLAIVPTAATAPILII
                     VGIMMLGSLKNIHWDDMSEAVPAFFTSIFMGFSYSITQGIAVGFLTYTLTKLVKGQVK
                     DVHAMIWILDALFILNYISMAL"
     gene            9592..10404
                     /locus_tag="VYO11_001794"
     CDS             9592..10404
                     /locus_tag="VYO11_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV1596311.1"
                     /translation="MTKKIIAVDLDGTLLNSDSQISDFTKKTIKKVAEKGHQVIITTG
                     RPYRMSKDFYRELGLDTPMINFNGSLTHLPDQVWDFEKCLTVDKKYLLDMVQRSEDIQ
                     ADFIAGEYRKKFYITNPNEEIANPKLFGVEAFQPEDQFQPELVTKDPNCILLQTRASD
                     KYALAKDMNAFYQHQLSINTWGGPLNILECTPKGVNKAFALDYLLKIMNRDKKDLIAF
                     GDEHNDTEMLAFAGKGYAMKNANPELLPYADEQISLTNDQDGVAKTLQDLFL"
     gene            10743..11762
                     /gene="adhP"
                     /locus_tag="VYO11_001795"
     CDS             10743..11762
                     /gene="adhP"
                     /locus_tag="VYO11_001795"
                     /EC_number="1.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase AdhP"
                     /protein_id="HEV1596312.1"
                     /translation="MKAVVVNPESTGVAIEEKVLRPLETGEALVEVEYCGVCHTDLHV
                     AHGDFGQVPGRVLGHEGIGIVKEIAPDVKSLKVGDRVSVAWFFEGCGTCEYCTTGRET
                     LCRTVKNAGYSVDGGMAEQCIATADYAVKVPDGLDPAQASSITCAGVTTYKAIKEAKV
                     EPGQWVVLYGAGGLGNLAVQYAKKVFNAHVIAVDINNDKLTLAKEVGADIVINGLEVE
                     DVAGLIKEKTDGGAHSAVVTAVSKVAFNQAVDSIRAGGRVVAVGLPSEMMELSIVKTV
                     LDGIQVIGSLVGTRKDLEEAFQFGAEGLVVPVVQKRPVEDAVAIFDEMEKGQIQGRMV
                     LDFTH"
BASE COUNT         3651 a         2569 c         2252 g         3358 t
ORIGIN      
        1 agatataatt tagattatta cctaattatc agagaaagct tattgtatgt attacataca
       61 aaccgccttt atacaacaca taaagatagc tcaggatatg aaaaaatctc taggagcgca
      121 atcttacaat acgagttaga caaacaaaag gggcatatct ttatcaaagc tctgattact
      181 ggtgatgaat ttagtaaaag ggtacaatca cttgatgatg ttcttgctgg agtactcgaa
      241 ctggaactag aatacaaaat tattcgtcct agttttatgg aataccattt ctattacaag
      301 aaacctgaca ggttagttct tcaatctcac aaccagaagc aagagataga taaccttaat
      361 atagatttag gatacggtgt gaattataat cctatcaagt gtcctcatat tctagttgcc
      421 ggaggtacag gaagcgggaa atcagtattt atatctttaa ggaaatcact ttgttaaacg
      481 ctataaaaca agaaaggagg ctaaagaagc tgaattagaa attctaacaa agatacatca
      541 acttgaaaat ggagaggata tcccactcct taaaactagt gatattcttt tctctgagtt
      601 ctttaataat atttggtggg attcatacaa agctggtcaa acaacttcaa caactaaacc
      661 cccaacacaa gttactattg ataatactga aatagttttc aggaagcaca tcttaccaat
      721 gttcggtaat tattcaatca attttctgaa tcagaataag caaatcgtac taaacttaat
      781 gactgctaaa gctgaagaat atgctaattt caaggttatt cgaagctatg taaactcaat
      841 tttcgattgg gctgaagaat tagaatacat tgaatcaaat agattatcaa aaagcataaa
      901 acgtattaaa gcaagtaaaa aaataaagct agaagaagct aaggatgagg aagatttgta
      961 tctatctagt gaagaattac aagattggtt tgatgctttt agagaagatt tggagaacga
     1021 caaattatca ctaaaagatt atgtcctatt ctttacaacc tttattttga gcgatagaaa
     1081 atcagaatcc tatgctctac attggaaaaa catagacttg gcaaacgctc aaattggctt
     1141 aaggcatgca cttgacaaat ataagaatgt aaagtcaaca aaaggaaata agaaaacgat
     1201 tttttcaatt cctagttacc ttgtatcact tctttcagaa tggaaaaaac agcagaaata
     1261 tgagttagcg aaatttggta taatgcaaac atccgatcaa ctagtcttta cctatataga
     1321 tacgaaaggt aatgtaaata gccctctaca cgttgattat ctcaataaca aaatgaactc
     1381 tgtaaaaaga cgacacccaa agttaaaaca cgctacacct cataaattac gacatacagg
     1441 agcgacactt gctaaaaagg caggaatgag cttagaagcc atttctgaag tattaactca
     1501 tagtgataca attacaacta aaacttatgt taatgcttca aacatagttc cattatctgc
     1561 tggacaagtt gcctaccaac atcttaaaaa caagtagggt aattttaggg caaattttag
     1621 ggaaaacttt tttagaaagt atagaaaaaa gcacccatag ggcaaacctt tgagtgcttt
     1681 gaaacattga tataatcgta ttgattaacg ttttgaggca actgaccttg tcaggttgca
     1741 gccacatttg taagcgacta aagtcgcaac aactgtgtca attgcaccaa tttagtaaga
     1801 aagtataaaa aaagaacacc ccgaaaggtg ctctgtataa gtatagtaat tctttcgaat
     1861 taacgtttac taaattgtga tgctttacga gctttcttaa gacctggttt cttacgttca
     1921 actttacgtg agtcacgtgt aagaagtcct gcgcgtttca atgaatcgcg gaagtctggg
     1981 tctacttgaa gaagggcacg agcgataccg tgacggatag ctcctgattg accagcgtat
     2041 ccaccaccta caacgttaac gaaaacgtcg tatgaaccta cagttgaagt aactgcgaat
     2101 ggttggttga tgacaagacg aaggtcagcg tgtgggatat actcttcaac atcttttttg
     2161 ttaacagtga ttttaccagt tcctggaaca aggcgaacgc gtgcaacagc gtttttacga
     2221 cgtccagtac ctgcatattg tgcttgtgac atactttatt tgttcctttc cttagataag
     2281 tcctgaaatg tcaagaactt ctggttgttg tgcagcatga gtgtgctcag ctccaacaaa
     2341 tactttcaac ttcatacctt gagcgcgtcc aagtgtattg tgtggaagca tacctttaac
     2401 tgatttctca atcaaacgta ctgcattttt agaacgaagt tcacctgcag agatttgttt
     2461 caatccacct gggtggtttg agtgagtgta gtagatttta tcagttgctt ttttaccagt
     2521 caatttaact ttttcagcat tgataacaat cacgaagtca cctgtatcag tgtgtggtgt
     2581 aaatgttggt ttgttttttc cgcgaagtac gctagcaact actgcagaaa gacgtccaag
     2641 tggtacatca gttgcgtcaa ctacgtacca tttacgttca acttggcctg gtttagccat
     2701 aaatgttgtt ttgttcatga tttctcctat atatagttcg atttttgttt acggtgatgg
     2761 gtgttccttc ccatcgaaaa gtatttggaa ggttccgggg cctttcaaat ggggtaaaca
     2821 ataccgccta ctatcatacc aaatttcacc cctaaaagtc aatagatata aaaaatattt
     2881 ttcggtaact tctcaaaata actgaaagtt atataatcaa gttaatttgg gaatttacct
     2941 attaacttcg gtagattttt gggaattttt tccctatttc tccctgtaac taaaatcctt
     3001 ttcaaaaaat caccttttct tgatttttaa tcctatttgc tgtatgataa gggaaaagaa
     3061 aggggacaga gatatggctt ttaccaatac ccacatgcgg tctgctagtt ttggcattgt
     3121 taccagcttg cccgatgaca tcattgactc tttttggtat atcatcgatc atttcttaaa
     3181 aaatgtcttt gaattggaag aagaactcga gtttcaattg cttaataacc aaggaaagat
     3241 taccttccac ttttcaagtc aacacctccc tacagccatt gattttgact ttaaccatcc
     3301 tttcgaccct cgttatcccc caagagtact ggttttagac atggacggta gagaaactat
     3361 cctcctccca gaagaaaatg acctatttta aaaactctag ccttcagttg caagtaactg
     3421 aaaactagag tttttctatt ttttcaaagc atcatacaag ttgcggatcg gttgttttaa
     3481 tatcggatgg ataaaatgag gcgcaatttc ctgtaaggac tcaaggacaa aaaggcgttc
     3541 cgctatgtaa ggatgaggca atatgaggtc gtctgtataa aggatctggt cctccacaaa
     3601 gagcaagtcc aaatcaatca aacgaggtcc ccaatgcact tctctcaccc gtcccagctc
     3661 tgactcaatg gctaacaagg tttctaacaa gtcttgtgct ggtagccagg tttccacctc
     3721 aaccacttga ttggcaaagc tatcctgctc cactccaccc caaggctccg tctctaagac
     3781 actggactct ttgagaatat ggatgccacg agctcgcagt ttgtcaatgg cttgcttcaa
     3841 gtttacttgt ttatctccca tattgcttcc tagggcgata aaggctcgtt gcttgcggcg
     3901 atgaatggtt accgagcaag tatctagtga caaatgcacc ggtgcccaag gttttttcag
     3961 ttccaacttc atttcttgga caagaggata agactcaaag gtacgttcca ccagtttata
     4021 ggctaccgtt tcaatcaaat cttcactcgt ttcctgaaac caagtcgtcc actgctgaca
     4081 caattctccg taatggacag aggctgttaa atccaagtct gtagctgcct tggtcatatc
     4141 ataggatagg atggctgaaa cgacaaattt ctgccccaat tctttctcac taggaaaaag
     4201 accatgatag gcaaacattt ccaaatcctt aatctgcagt tgatccataa tgattccttt
     4261 ctagaaaaat ccgcttgaag cggattcttt ttatagcccc attaaacgat aagcttggtc
     4321 acggagatcc ttatctgttt caaatagacc acgagctact gtcgtcaagg ttgcagtgcc
     4381 tggttttcta acaccacgca tactcataca catatgttcc gcctcaatga caacaaaggc
     4441 tcctttagca cctagatagt ccatcaaggc atcggccact tcgatattca aacgttcttg
     4501 aatttgtggt tttttcgaat aaacttcaac cgtacgggct agcttagaca agcctgccac
     4561 acgaccatct ggaatgtagg caatgtgcgc tctaccataa aatggcaaga agtggtgttc
     4621 acacatggta tggaaaaaga tatccttttc taccaccata ttatcgtcaa taatttcaaa
     4681 ggattttgac aaatgttcct ctgctgtttg accaagacct gaaaaaatct cttgatacat
     4741 acgggctaca cgagcaggtg tttcctgcaa gccctcgcga ttaacgttct ctcctacagc
     4801 ctcgataatc atttttacag ctgcttcaat cttttgtgta tccattctcg ttcttcctct
     4861 ccatcagata ggccctcact tggctcaaga aatacaagga acctgtgaca atcctaactg
     4921 tttgtttctc ttctttttta tctgtcaaat tctgatctag aaaatcatgc caatcttggt
     4981 agctgagatt tctagactta gctgcctctt tcagcacgct ttcatccgtc gcccgactat
     5041 ccgcaaaatg tgttagagta agctcggtat ctggcatggc tcccagcaag tccaacatat
     5101 cctccaaggc tttggttttg atacaagtga agaggatttc cttatgatga tccgcaaaac
     5161 gttcttgcaa ggttaccaac aaggccttga tagcatgggg attatgggct ccatccaaaa
     5221 tcatcaaggg atctcttgac acgatttcca aacgccctgg ccaacttgtt tcttccaagg
     5281 cttgaccaag aaagtcattg cttgctagct ctcgaccatc ttcttgacaa aaagtatcaa
     5341 gtaaagctat ggccatccca gcattctcta tttggtacaa accaagcagg ctagtctgga
     5401 agcgaccttg tctgacagca cttgtatagt caaagacttc ccctgtcacc acactttctt
     5461 gatgacgaac ctgataatct gtcccgtagg caagtctcgg cgcatctttc ccttccgcaa
     5521 tgcggtcaat cacagtcaag gcttctggag caatacgccc tgttaccaag ggcatccctt
     5581 gtttgataat acctgccttc tgctctgcta tgacctccaa ggtgtcacca agtagggcca
     5641 catgatccaa gccaatagtt gtaattcctg tcaaaatggg ctgacagaca ttggtactat
     5701 ccaaaagtcc acccatgcca acttccatga tggccacatc tacttgctct gaggcaaagt
     5761 agtcataggc cagggctgtg ataatctcaa actcggttgt gccctgtaaa ttggcgaccg
     5821 cttctccctc cagcaaagac tgatagtctg ccatgagggt ttctagtctc gcttccggga
     5881 tagattcccc attgatgcta atctgatctg tgtaatgaat gagataggga gagctgaaaa
     5941 cgccaactct cagccctagc ttttccagca gatttttcaa aaaagcaatg gtcgaaccct
     6001 tgccgttggt ccctccgata tggatgacct tgagtttgag atggggattg ccacgcaatg
     6061 ctaacagttc catcattcgt tccaagccaa aatgcggttg gtccgtccga taattagcaa
     6121 tccactgatt gttttcaatt tctttcatat tatttatatt gttttaaatc tagattttcc
     6181 gcttcatcag ccagacgaat agtggaggca atttcaactg ccatcctgtg actagctacg
     6241 tcatgcacgc gcactacttc tactccctgc ctcgcagcga tactagttac atgagccgaa
     6301 gctgtgtccc gattacggaa accaagttct gtctcaggat tgacttcaaa accactttct
     6361 tcaaggatat tgatgacaaa ccgcttgcgc gacactccaa gaaagattgg atagcccttc
     6421 tgatggagtc tatccaggtc ccgtaaaaga agtagatttt ctttcttggt cagaccaaat
     6481 ccaatccctg gatccaacag gatattttct tgtgcgatcc cagcttgatt cgctctcgat
     6541 agggctctgt caaagaaagc ctccatcaag tcttcgattg gcaatgtttc aaagtcagct
     6601 aactcttcct ctgtaaaagc ttgaccaaag ccaaaatgag gaaatatgag cgagctagga
     6661 tgctgaggtc gcgccatgac tggattaaac ataatgacta ctttcgctcc agcctttgca
     6721 accacatggg ccattttttc atcacccata agaccagtga tatcattgac tagattggca
     6781 ccagcagcca aagcagcctc tgccacctga cttttccaag tatcaataga aatgaggaca
     6841 tcactttcct tgcgaatcgc tttgatcact ggaacaacac gctggatttc ctcttctatc
     6901 tcaacatagc tacttcccgg ccgaggccga gtcgattctc cgccgatatc gagcatactg
     6961 gctccttccg ctatcaattt acgagcctgc tggagtgcct gctcaagagc aaaaaattga
     7021 ccaccgtccg aaaaggagtc tggggttaca ttgataattc cgcaaatagc tgtctttgca
     7081 tgattggctt tacttgacat atcggtcact ccctcaaggc ttttcaccat attatttctc
     7141 tattttacca taaaaagaaa aagatggaca cgattgcatt catctttttc ccattagaaa
     7201 caagtaagca attgtcaaaa atcttaaaca gaaatcccta atgtccgact catgatcacc
     7261 acaagagcta gcaaacagaa aacaacccca ttcacaatca tgtgaagtaa gatagacatt
     7321 tccaaacgtt gggtcttgta agccgtccaa gacagaacga tcgacataac tccataaatc
     7381 aataaagaag gtaaattact tggttgatgc aataaagcaa acacaatcgt accgactaca
     7441 aatcccaagt tctccttgcc tcggaaaatc tttttaggaa caatcccacg acacaagatt
     7501 tcctcacaaa tcggagcaag caaggctagc aagaagaagc tagaaatcag agaactattc
     7561 tgaaccatat cgttaatctg agactggtta gctgttgtcg tctcatttga cagttgtaac
     7621 aagatagaac caagtatatt tgaacagata atgactaaat aactcaagcc caaacgtgcc
     7681 aaatccttag ctctaaaaaa agaaaaatta aaacttgcta actgcgtttt acgagctcca
     7741 aaaataaata gtgccaacac tacaatcgaa agaccagcaa ctatcagtcc tgactgtagc
     7801 agggctactt cttttaaagt caaaatagag gtaaccacta ggggaacctg atataaaagg
     7861 acggcaagta aaaagaccaa aatccagcct gcacgattca acaattcttt ccacatattt
     7921 ttctctttta tcacctatct cctttgtatt aaaaaagggg ggaaatcccc ctgggtcatt
     7981 ctattataag gccatgctga tgtagttaag gataaacaag gcatccaaaa tccaaatcat
     8041 ggcatgaaca tctttaactt gacctttgac aagcttagtc aaagtgtaag tcaagaaacc
     8101 aactgcaatc ccttgagtga tagagtagct gaatcccata aagatagatg tgaagaaggc
     8161 aggaactgct tcagacatat catcccaatg gatatttttc aagctaccaa gcatcataat
     8221 cccaacgata atcaagattg gagctgtagc cgctgttggt acgatcgcta gaagcgggct
     8281 aaagaagctt gaaatcgcaa aacagatagc tacaaccaag gctgtcaaac cagtacgtcc
     8341 acctgcaccg ataccagcag cagactcaac ataagtcgtt acgtttgaag tacctgcaat
     8401 ggcaccgact gtcgttccaa tcaaatcaga gtaaagagcc ttatccaatt tggctgattg
     8461 gtgattttca ccatttgtcg ctacaatacc aactttttca cctgtaccga tcaaggtacc
     8521 aattgtgtca aaaatatctg tcaatgagaa ggcaagaatg gccatcagag tttcaggcaa
     8581 gcgagctgta tctgaaacca aagctcccaa accttctgaa ccaagagctg caccaaagat
     8641 tgtcttcaaa tcttcaaaag ctgcaccaac atggttatta gcaaaatcga tactagacaa
     8701 atcaaccaaa ccaactgcaa tagcaagaac agttgttgtc aagatagaga gaataattcc
     8761 ccctttaatc cctttgatga caaagaagat agtaatggca agtcctgcaa gagccactaa
     8821 aacagctgga ttattaaagc tgaccaatcc tggaactgct gaagagtttg ctgcaatcgt
     8881 tgcttgagct ttgtcagccc cttctcctac aacagtatag ttgcctggat caatcgtgaa
     8941 tttcaaaagt ccagcattct taatccctac ataggcaagg aagacaccga taccagctga
     9001 aatagctgag cgaagagcat tgggaatcga ttcaatgatc attttacgaa catttgtcaa
     9061 ggtaataatc aatgaaataa tcccacagat gaagaccata gctagggctt cttgccaaga
     9121 ataaccaagc ccgaatacaa ctgtaaaggt aaagaaggca ttgagtccca tacctggcgc
     9181 ttgggcataa ggtaagttag cataaaaagc catcatcaag gtacccgcta ctgcaccaat
     9241 aatcgtcgct aggaagacgc cctgagcagg cattcctgtt tgtgaaagta tttgtgggtt
     9301 tacaaagaga atatagctca ttgcaaagaa agttgttaaa ccagcgagaa cctctgtacg
     9361 aacgtctgta ccgttctctt ttagtttaaa taatttgtcc atcatcaatc tccttttaat
     9421 ttttacgaac aataatagaa ttatatcatt tatcattcac tttttcaatg tatttgtttg
     9481 atttgtttaa gaaattaatc caatttcatt ttttgtttgg aatctgcttt tctgcctgct
     9541 ttctgttata atagaagaca tcttatctga aaacacacta gaaaggtcca tatgacgaaa
     9601 aaaattattg cagttgacct ggatggaacc ctgctcaact cagacagtca aatttctgac
     9661 tttaccaaaa aaaccatcaa aaaagttgct gaaaaaggcc atcaggttat tattacgaca
     9721 ggtcgccctt accgtatgtc aaaagatttt taccgtgaac tgggcttaga cactcctatg
     9781 attaacttca acggatccct tactcattta ccagaccaag tttgggattt tgaaaagtgt
     9841 ttgactgtag acaaaaaata tctgctagat atggttcaac gttcagagga cattcaagcc
     9901 gattttatcg ctggagaata tcgtaaaaaa ttctacatta caaatcccaa tgaagaaatt
     9961 gccaatccca aactatttgg tgtagaagct ttccagcctg aagatcaatt ccagcctgaa
    10021 ttggtgacca aggaccctaa ctgtatcctc ttgcagacca gagccagtga caaatatgcc
    10081 ttggcaaaag acatgaacgc cttctaccag catcaacttt ctatcaatac ctggggaggt
    10141 ccgctcaata tccttgaatg taccccaaaa ggtgtcaaca aggcctttgc tttggactac
    10201 ttgctcaaga taatgaatcg tgacaaaaaa gatttgattg cctttggaga tgaacacaat
    10261 gataccgaaa tgctcgcttt tgctgggaag ggttatgcca tgaaaaatgc caatccagag
    10321 ctactccctt atgcagatga gcaaatttcc cttaccaacg accaagatgg ggttgccaaa
    10381 accctacaag acttattctt ataacctata ctgatactca atgagaatca aagagcaaac
    10441 taggaagcta gccgtaggtt gctcaaagca ctgctttgag gttgtagatg aagctgacgt
    10501 ggtttgaaga gattttcgaa gagtatgacc agcttgcaag ctggtctttg tgctcttttc
    10561 acagtctcat caaccagtta atcgattgtt ctactttttg tctccaaaac cttggaaaag
    10621 gcttcctttt gtgatatact tcacatataa atacaagaga gctcgtcaca ctcgactctg
    10681 ttgacaaaaa atcaatccag tcccgttgtc cctgttctcg gtcaatatca aggaggatag
    10741 ctatgaaagc tgttgttgta aatccagaaa gcactggtgt tgctattgaa gaaaaagtac
    10801 tccgtccact tgaaactggg gaagcacttg tagaagttga atactgtggc gtttgccaca
    10861 ccgacctcca cgttgctcat ggtgactttg gtcaagtccc aggacgtgtt cttgggcacg
    10921 aaggtatcgg tatcgttaaa gagattgctc cagatgtgaa aagccttaaa gtcggtgacc
    10981 gcgtcagcgt tgcttggttc tttgaaggat gtggcacttg cgaatactgt acaactggtc
    11041 gcgaaaccct ttgccgtaca gtgaaaaatg ctggctactc agtagacggt ggtatggctg
    11101 aacaatgtat cgcaactgct gactatgctg tcaaagttcc tgacggactt gatccagccc
    11161 aagcttcttc tatcacatgt gctggagtaa caacctataa agctatcaaa gaagcaaaag
    11221 ttgaaccagg ccaatgggtt gttctttacg gtgctggtgg acttggtaac ctcgctgttc
    11281 aatacgctaa aaaagtattc aatgctcatg ttatcgcagt cgatatcaac aatgacaaac
    11341 ttacccttgc aaaagaagta ggcgctgaca ttgtgattaa cggcctcgaa gttgaagatg
    11401 tagctggact cattaaagaa aaaactgatg gaggagctca ttcagctgtc gtaactgctg
    11461 tgtctaaagt tgccttcaac caggctgttg actccattcg tgctggtggt cgcgtcgtcg
    11521 ctgttggtct tccttctgaa atgatggaac tcagcatcgt taaaacagtc ctcgatggaa
    11581 tccaagtcat cggttctctt gtcggaactc gtaaagactt agaagaagcc ttccaatttg
    11641 gtgcagaagg tctggtagtc ccagttgttc aaaaacgtcc agtagaagat gctgttgcca
    11701 ttttcgacga aatggaaaaa ggccaaatcc aaggacgtat ggtactcgac ttcacccact
    11761 aatttaatag aaacctattt taaaagttgg aagcttcttc caactttttt atattaaatt
    11821 ttaaataaga
//
LOCUS       DAVLXH010000058        11565 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00028199
            SAMN33607166-rid17955573.denovo.058, whole genome shotgun sequence.
ACCESSION   DAVLXH010000058 DAVLXH010000000
VERSION     DAVLXH010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607166
            Sequence Read Archive: SRR23725544
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11565)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11565)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721421.1
            Genome Coverage       :: 115x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:42:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,210
            CDSs (total)                      :: 2,161
            Genes (coding)                    :: 2,023
            CDSs (with protein)               :: 2,023
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 73 of 138
            Pseudo Genes (incomplete)         :: 60 of 138
            Pseudo Genes (internal stop)      :: 40 of 138
            Pseudo Genes (multiple problems)  :: 31 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11565
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607166-rid17955573.denovo.058"
                     /strain="AUSMDU00028199"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1349"
     gene            731..1723
                     /locus_tag="VYO11_001796"
     CDS             731..1723
                     /locus_tag="VYO11_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV1596313.1"
                     /translation="MAMIEVEHLQKHFVKIVKEPGLKGALRSFIHPEKQTFEAVKDLT
                     FEVPKGQILGFIGANGAGKSTTIKMLTGILKPTSGFCRINGKIPQDNRQDYVKDIGVV
                     FGQRTQLWWDLALQETYTVLKEIYDVPNSLFHKRMDFLNEVLDLKDFIKDPVRTLSLG
                     QRMRADIAASLLHNPKVLFLDEPTIGLDVSVKDNIRRAITQINQEEETTILLTTHDLS
                     DIEQLCDRIFMIDKGQEIFDGTVSQLKETFGKMKTLSFELLPGQSHLVSHYEGLSDMT
                     IDRQGNSLNIEFDSSRYQSADIIKQTLSDFEIRDLKMVDTDIEDIIRRFYRKEL"
     gene            1725..2543
                     /locus_tag="VYO11_001797"
     CDS             1725..2543
                     /locus_tag="VYO11_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 family transporter protein"
                     /protein_id="HEV1596314.1"
                     /translation="MIKLWRRYKPFINAGVQELITYRVNFILYRIGDVMGAFVAFYLW
                     KAVFDSSQESLIQGFSMADITLYIIMSFVTNLLTRSDSSFMIGEEVKDGSIIMRLLRP
                     VHFAASYLFTELGSKWLIFISVGLPFLSVIVLMKIISGQGIVEVLGLTVLYLFSLTLA
                     YLINFFFNICFGFSAFVFKNLWGSNLLKTSIVAFMSGSLIPLAFFPKVVSDILSFLPF
                     SSLIYTPVMIIVGKYDASQILQALLLQFFWLLVMVGLSQLIWKRVQSFITIQGG"
     gene            2545..3330
                     /locus_tag="VYO11_001798"
     CDS             2545..3330
                     /locus_tag="VYO11_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1596315.1"
                     /translation="MKKYQRMHLIFIRQYIKQIMEYKVDFVVGVLGVFLAQGLNLLFL
                     NVIFQHIPFLEGWTFQEIAFIYGFSLIPKGMDHLFFDNLWALGQRLVRKGEFDKYLTR
                     PINPLFHILVETFQIDALGELLVGGILLGTTVTSIVWTLPKFLLFLVCIPFATLIYTS
                     LKIATASIAFWTKQSGAMIYIFYMFNDFAKYPISIYNSLLRWLISFIVPFAFTAYYPA
                     SYFLQEKDVFFNVGGLMLISLVFFVISLKLWDKGLDSYESAGS"
     gene            3428..3646
                     /locus_tag="VYO11_001799"
     CDS             3428..3646
                     /locus_tag="VYO11_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family acetyltransferase"
                     /protein_id="HEV1596316.1"
                     /translation="MKDLPEWFGIPESTQAYIEGTTTLQVWTAYQESDLTGFVSLSYS
                     SEDCAEIDCLGVKKLIKVEKLGANCLLL"
     gene            3631..3828
                     /locus_tag="VYO11_001800"
     CDS             3631..3828
                     /locus_tag="VYO11_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1596317.1"
                     /translation="MLATLESEAHKKVGYLQVKTVAEGSNKDYDRTNDFYRGLGFKKL
                     EIFPQLWNPQNPCQILIKKLE"
     gene            complement(4254..4328)
                     /locus_tag="VYO11_001801"
                     /pseudo
     CDS             complement(4254..4328)
                     /locus_tag="VYO11_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829418.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            4561..10995
                     /locus_tag="VYO11_001802"
     CDS             4561..10995
                     /locus_tag="VYO11_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HEV1596318.1"
                     /translation="MKKSTVLSLTTAAVILAAYAPHEVVLADTSNSEDALSISDKEKV
                     VVDKETENKEKHKDIHNAIETSKDTEEKKTTVIEEKEVVSKNPVIDTKTSNEEARIKE
                     DSNQSQGDNAHSSANKGTENPKKEDRLVYIAEFKDKESGEKAIKGLSNLKNTKVLYTY
                     DRIFNGSAIETTPDNLDKIKQIEGISSVERAQKVQPMMNHARKEIGVEEAIDYLKSIN
                     APFGKNFDGRGMVISNIDTGTDYRHKAMRIDDDAKASMRFKKENLKGTDKNYWLSDKI
                     PHAFNYYNGGKITVEKYDDGRDYFDPHGMHIAGILAGNDTEQDIKNFNGIDGIAPNAQ
                     IFSYKMYSDAGSGFAGDETMFHAIEDSIKHNVDVVSVSSGFTGTGLVGEKYWQAIRAL
                     RKAGIPMVVATGNYATSASSSSWDLVANNHLKMTDTGNVTRTAAHEDAIAVASAKNQT
                     VEFDKVNIGGESFKYRNIGAFFDKNKITTNEDGTKAPSKLKFVYIGKGQDQDLIGLDL
                     RGKIAVMDRIYTKDLKNAFKKAMDKGARAIMVVNTVNYYNRDNWTELPAMGYEADEGT
                     KSQVFSISGDDGVKLWNMINPNKKTEVKRNNKEDFKDKLEQYYPIDMESFNSNKPNVG
                     DEKEIDFKFAPDTDKELYKEDIIVPAGSTSWGPRIDLLLKPDVSAPGKNIKSTLNVIN
                     GKSTYGYMSGTSMATPIVAASTVLIRPKLKEMLERPVLKNLKGDDKIDLTSLTKIALQ
                     NTARPMMDATSWKEKSQYFASPRQQGAGLINVANALRNEVVATFKNTDSKGLVNSYGS
                     ISLKEIKGDKKYFTIKLHNTSNRPLTFKVSASAITTDSLTDRLKLDETYKDEKSPDGK
                     QIVPEIHPEKVKGANITFEHDTFTIGANSSFDLNAVINVGEAKNKNKFVESFIHFESV
                     EEMEALNSNGKKINFQPSLSMPLMGFAGNWNHEPILDKWAWEEGSRSKTLGGYDDDGK
                     PKIPGTLNKGIGGEHGIDKFNPAGVIQNRKDKNTTSLDQNPELFAFNNEGINAPSSSG
                     SKIANIYPLDSNGNPQDAQLERGLTPSPLVLRSAEEGLISIVNTNKEGENQRDLKVIS
                     REHFIRGILNSKSNDAKGIKSSKLKVWGDLKWDGLIYNPRGREENAPESKDNQDPATK
                     IRGQFEPIAEGQYFYKFKYRLTKDYPWQVSYIPVKIDNTAPKIVSVDFSNPEKIKLIT
                     KDTYHKVKDQYKNETLFARDQKEHPEKFDEIANEVWYAGAALVNEDGEVEKNLEVTYA
                     GEGQGRNRKLDKDGNTIYEIKGAGDLRGKIIEVIALDGSSNFTKIHRIKFANQADEKG
                     MISYYLVDPDQDSSKYQKLGEIAESKFKNLGNGKEGSLKKDTTGVEHHHQENEESIKE
                     KSSFTIDRNISTIRDFENKDLKKLIKKKFREVDDFTSETGKRIEEYDYKYDDKGNIIA
                     YDDGSALQYETEKLDEIKSKIYGVLSPSKDGHFEILGKISNVSKNAKVYYGNSYKSIE
                     IKATKYDSHSKTMIFDLYANINDIVDGLAFAGDMRLFVKDDNQIKAETKIRMPEKNKE
                     TKAEYPYVSSYGNVIELGEGDLSKNKPDNLTKMESGKIYSDSEKQQYLLKDNIILRKG
                     YALKVTTYNPGKTDMLEGNGVYSKEDIAKIQKANPNLRVLSETTIYADSRNVEDGRST
                     QAVLMSALDGFNIIRYQVFTFKMNDKGEAIDKDGNLVTDSSKLVLFGKDDKEYTGEDK
                     SNVEAIKEDGSMLFIDTKPVNLSMDKNYFNPSKSNKIYVRNPEFYLRGKISDKGGFNW
                     ELRVNESVVDNYLIYGDLHIDNTRDFNIKLNVKDGDIMDWGMKDYKANGFPDKVTDMD
                     GNVYLQTGYSDLNAKAVGVHYQFLYDNVKPEVNIDPKGNTSIEYADGKSVVFNINDKR
                     NNGFDGEIQEQHIYVNGKEYTSFDDIKQITDKTLNIKIVVKDFARNTTVKEFILNKDT
                     GEVSELKPHRVTVTIQNGKEMSSTIVSEEDFILPVYKGELEKGYQFDGWEISGFEGKK
                     DAGYVINLSKDTFIKPVFKKIEEKKEEENKPTFDVSKKKDNPQVNHSQLNESHRKEDL
                     QREDHSQKSDSTKDVTATVLDKNNISSKSTTNNPNKLPKTGTASGAQTLLAAGIMFIV
                     GIFLGLKKKNQD"
BASE COUNT         4046 a         1732 c         2316 g         3471 t
ORIGIN      
        1 tatttcaatc cgctatatat tatggtatcg aatcttcatc agaatgataa aattaatcaa
       61 ttaatatctg attacaaaca gaatatgaaa gctttttata tcactattga aaaatttata
      121 cgagatgatg aaagccttaa gtgttatttt acaaaggtta tttcaagtcg ttccaaggta
      181 acaagtctag atcagattga agctgataaa acgatacaaa gaaaatattc aagtgagcta
      241 aaaaaattta ttggatttta taatgagatt atttgtgagg aaaatagttt cctacatgta
      301 cgaaagaggt ggtcgagttg gtttaggtag tcggtgcgtg agttgataat tctcagggta
      361 tggacttctt tttcatgaat gaggtaaaag agcaggtatt gtttagagac aatcattctg
      421 agcatatttt ctggatagag ggagtatccg attttatgat caaagttaat accgccctct
      481 ggtgagaaga tgagtaggtt ggtaatttaa actattaaac agaatttttg attaaaagta
      541 ttatttcatg agagaaatcc taatttcaca attcataggt aaacgcttgc attctgtttt
      601 ttattggact ataataggtt ggtataaagc cttctgtagt aataaaatgt agaaggtgta
      661 gaaagtaagg atttagaata tttgtagtta aaaacacaat gttgctattc cttacgatag
      721 ggagatagat atggcaatga tagaagtgga acatcttcag aaacattttg tgaagattgt
      781 taaggaaccg ggcttgaagg gggctttgcg ctcctttatt catcctgaaa agcagacctt
      841 tgaagcggtc aaggatttga cctttgaggt tccaaaaggg cagattttag gatttatcgg
      901 ggcaaatggt gctgggaagt cgacaaccat taaaatgctg acaggaattt tgaaaccaac
      961 atctggtttt tgtcggatta acggcaagat tccccaggac aatcggcaag attatgtcaa
     1021 agatattggc gtagtctttg gacaacgcac ccagctatgg tgggatttgg ctctgcaaga
     1081 gacctacact gtcttaaaag agatttatga tgtgccaaac tcgctctttc ataagcgcat
     1141 ggactttttg aatgaagtct tggatttgaa ggactttatc aaggatcccg tgcggactct
     1201 ttcactggga caacggatgc gggcggatat tgcggcctcc ttgctccaca atcccaaggt
     1261 tcttttttta gatgagccga ccattggttt ggacgtttcg gttaaggata atattcgtcg
     1321 ggcaattact cagattaatc aagaggaaga aactaccatt cttttgacca ctcacgattt
     1381 gagtgatatt gagcaacttt gtgatcggat tttcatgatt gacaaggggc aagagatttt
     1441 tgatggaacg gtgagccaac tcaaggagac ctttggtaag atgaagactc tctcttttga
     1501 actgctacca ggtcaaagtc atctcgtctc tcactatgaa ggtctgtctg atatgaccat
     1561 tgatagacaa ggaaacagcc tcaacattga atttgatagt tctcgctacc agtcagctga
     1621 cattatcaag caaaccctgt ctgattttga aatccgcgat ttgaagatgg tggatacgga
     1681 tattgaggat attatccgtc gcttctaccg aaaggagctc taggatgatc aaattgtgga
     1741 gacgttataa accctttatc aatgcagggg ttcaggagtt gattacttac cgagtcaact
     1801 ttattctcta tcggattggc gatgtcatgg gggcttttgt ggccttttat ctctggaagg
     1861 ctgtctttga ttcttcgcaa gagtctttga ttcagggctt cagtatggcg gatatcaccc
     1921 tctacatcat catgagtttt gtgaccaatc ttctgactag atccgattcg tcctttatga
     1981 ttggggagga ggtcaaggat ggctccatta tcatgcgttt gttgcgacca gtgcattttg
     2041 cggcctccta tcttttcacc gagcttggtt ccaagtggtt gatttttatc agcgttggcc
     2101 ttccattttt aagtgtcatt gtcttgatga aaatcatatc gggtcaaggt attgtagagg
     2161 tgctaggatt aactgtcctt tatcttttta gcttaacgct cgcctatctg attaactttt
     2221 tctttaatat ttgctttgga ttttcagcct ttgtgtttaa aaatctttgg ggttccaacc
     2281 tacttaagac ttccatagtg gcttttatgt cggggagttt gattcccttg gcattctttc
     2341 caaaggttgt ttcagatatt ctctcctttt tgcctttttc atccttgatt tatactccag
     2401 ttatgatcat tgttggaaaa tacgatgcca gtcagattct tcaggcactc cttttgcagt
     2461 tcttctggct cttagtgatg gtgggattgt ctcagttgat ttggaaacgg gtccagtcct
     2521 ttatcaccat tcaaggaggt tagtatgaaa aaatatcaac gaatgcatct gatttttatc
     2581 agacaataca tcaaacaaat catggaatat aaggtggatt ttgtggttgg tgtcttggga
     2641 gtctttctgg ctcaaggctt gaatctcttg tttctcaatg tcatctttca acatattcca
     2701 ttcctagaag gctggacctt tcaagagata gctttcattt atggattttc cttgattccc
     2761 aagggaatgg accatctctt ttttgacaat ctctgggcac tagggcaacg cctagtccga
     2821 aaaggggagt ttgacaagta tctgactcgt cccatcaatc ctctctttca catcctagtt
     2881 gaaacctttc agattgatgc cttgggtgaa ctcttagtcg gtggtatttt attgggaaca
     2941 acagtgacca gcattgtttg gactcttcca aaattcctgc ttttcctagt ttgtattcct
     3001 tttgcgacct tgatttatac ttctcttaaa atcgcaacag ccagtatcgc cttttggact
     3061 aagcagtcag gcgccatgat ttacatcttc tatatgttca atgactttgc taagtatccg
     3121 atttctattt acaattctct tcttcgttgg ttgattagct ttatcgtgcc tttcgccttt
     3181 acagcctact atccagctag ctatttctta caggaaaagg atgtgttctt taacgtagga
     3241 ggtttgatgt tgatttctct ggttttcttt gttatttccc ttaaactttg ggataagggc
     3301 ttagattcct acgaaagtgc gggttcgtaa aagctaaagt aagactaaaa tcaagaaagg
     3361 aacttatgat gtttgtaatt gaagaagtca aggatgaaaa tcaaaaaagg cagttgtcgc
     3421 tgaggttttg aaggatttgc cagaatggtt tggaatccca gaaagcacac aagcctatat
     3481 agaaggaacc acgacactgc aagtttggac cgcctatcag gagagtgatt tgactggatt
     3541 tgtaagctta tcctattcga gtgaagattg tgcagagatt gattgtctcg gcgtaaaaaa
     3601 gcttatcaag gtagaaaaat tgggagccaa ttgcttgcta ctttagagag tgaagctcat
     3661 aaaaaagttg gttatctgca ggtcaaaaca gtggcagaag gttctaataa agattatgat
     3721 cgaacaaatg acttttatcg aggtcttggc tttaaaaagt tagagatttt tcctcaacta
     3781 tggaatccgc aaaatccttg tcagattttg attaaaaagc ttgaataata ttacttgaca
     3841 tctattctca gagtgctata ctgtaagtgt aatcgccgat ttagcttagt tggtagagca
     3901 aggcactcgt aaagcctagg ttataggtag ataaacgact gaggatttga aaaaatagat
     3961 aggtagaaga taaccgttaa gccttactct tagcggttat ttatattgtt taatagcgct
     4021 aatatttcat caattatgcc tgttttcgtg tttctggtag ttgttcaagt ttattgctac
     4081 tatttttgat ggtatgaatg tgcttataat gtatcccggt taacgaaagt tttggactta
     4141 tactcttcga aaatctcttc aaaccacgtc aacgtcgcct tgccgtgcgt atggttactg
     4201 actacgtcag ttctatccac aacctcaaaa cagtgttttg agctgactac gtcagttcca
     4261 tctacaacct caaaacagtg ttttgagcaa cctgcggcta gtttcctagt ttgctctttg
     4321 attttcattg agtactaatc ttatttttta acgtgtgcta aaaaataaat taatgcatgt
     4381 taatttttct tgaattaaat ttttttaaat gatatactgt ttttatggag agataacaat
     4441 tatatataaa tgtactactc tatttcctag ataatactta gtaaaacttt ttataacaaa
     4501 ggctagcaaa gttaaagttt attatctatt ggaagttaaa taaatatgta aggaattaaa
     4561 atgaaaaaaa gtacggtatt gtcattaacc acagctgcag ttattttagc agcctatgcc
     4621 cctcatgagg tagtcttagc agacacatct aactctgaag atgctttaag catctctgat
     4681 aaagaaaaag tagtagtaga taaggaaaca gaaaataaag agaaacataa agatattcat
     4741 aatgctatag aaacttcaaa ggatactgaa gaaaagaaaa caacagttat tgaggaaaaa
     4801 gaagttgtta gtaaaaatcc tgtgatagac actaaaacta gcaatgaaga agcaagaatc
     4861 aaagaagatt ccaatcaatc ccaaggagat aatgcacact cgtctgcaaa taaaggcaca
     4921 gaaaatccga aaaaagaaga tagacttgtc tatattgctg aatttaaaga taaagaatct
     4981 ggagaaaaag caatcaaggg actatccaat cttaagaata caaaagtttt atatacttat
     5041 gatagaattt ttaacggtag tgccatagaa acaactccag ataacttgga caaaattaaa
     5101 caaatagaag gtatttcatc ggttgaaagg gcacaaaaag tccaacccat gatgaatcat
     5161 gccagaaagg aaattggagt tgaggaagct attgattacc taaagtctat caatgctccg
     5221 tttgggaaaa attttgatgg tagaggtatg gtcatttcaa atatcgatac tggaacagat
     5281 tatagacata aggctatgag aatcgatgat gatgccaaag cctcaatgag atttaaaaaa
     5341 gaaaacttaa aaggtactga taaaaattat tggttgagtg ataaaatccc tcatgcgttc
     5401 aattattata atggtggcaa aatcactgta gaaaaatatg atgatggaag ggattatttt
     5461 gacccacatg ggatgcatat tgcagggatt cttgctggaa atgatactga acaagatatc
     5521 aaaaacttta acggcataga tggaattgca cctaatgcac aaattttctc ttacaaaatg
     5581 tattctgacg caggatctgg gtttgcgggt gatgaaacaa tgtttcatgc tattgaagat
     5641 tctatcaaac acaacgttga tgttgtttcg gtatcatctg gttttacagg aacaggtctt
     5701 gtaggtgaga aatattggca agctattagg gcattaagaa aagcaggcat tccaatggtt
     5761 gtcgctacgg gtaactatgc gacttctgct tcaagttctt catgggattt agtagccaat
     5821 aatcatctga aaatgaccga cactggaaat gtaacacgaa ctgcagcaca tgaagatgcg
     5881 atagcggtcg cttctgctaa aaatcaaaca gttgagtttg ataaagttaa cataggtgga
     5941 gaaagtttta aatacagaaa tataggggcc tttttcgata agaataaaat cacaacaaat
     6001 gaagatggaa caaaagctcc tagtaaatta aaatttgtat atataggcaa ggggcaagac
     6061 caagatttga taggtttgga tcttaggggc aaaattgcag taatggatag aatttataca
     6121 aaggatttaa aaaatgcttt taaaaaagct atggataagg gtgcacgcgc cattatggtt
     6181 gtaaatactg taaattacta caatagagat aattggacag agcttccagc tatgggatat
     6241 gaagcggatg aaggtactaa aagtcaagtg ttttcaattt caggagatga tggtgtaaag
     6301 ctatggaaca tgattaatcc taataaaaaa actgaagtca aaagaaataa taaagaagat
     6361 tttaaagata aattggagca atactatcca attgatatgg aaagttttaa ttccaacaaa
     6421 ccgaatgtag gtgacgaaaa agagattgac tttaagtttg cacctgacac agacaaagaa
     6481 ctctataaag aagatatcat cgttccagca ggatctacat cttgggggcc aagaatagat
     6541 ttacttttaa aacccgatgt ttcagcacct ggtaaaaata ttaaatccac gcttaatgtt
     6601 attaatggca aatcaactta tggctatatg tcaggaacta gtatggcgac tccaatcgtg
     6661 gcagcttcta ctgttttgat tagaccgaaa ttaaaggaaa tgcttgaaag acctgtattg
     6721 aaaaatctta agggagatga caaaatagat cttacaagtc ttacaaaaat tgccctacaa
     6781 aatactgcgc gacctatgat ggatgcaact tcttggaaag aaaaaagtca atactttgca
     6841 tcacctagac aacagggagc aggcctaatt aatgtggcca atgctttgag aaatgaagtt
     6901 gtagcaactt tcaaaaacac tgattctaaa ggtttggtaa actcatatgg ttccatttct
     6961 cttaaagaaa taaaaggtga taaaaaatac tttacaatca agcttcacaa tacatcaaac
     7021 agacctttga cttttaaagt ttcagcatca gcgataacta cagattctct aactgacaga
     7081 ttaaaacttg atgaaacata taaagatgaa aaatctccag atggtaagca aattgttcca
     7141 gaaattcacc cagaaaaagt caaaggagca aatatcacat ttgagcatga tactttcact
     7201 ataggcgcaa attctagctt tgatttgaat gcggttataa atgttggaga ggctaaaaac
     7261 aaaaataaat ttgtagaatc atttattcat tttgagtcag tggaagaaat ggaagctcta
     7321 aactccaacg ggaagaaaat aaacttccaa ccttctttgt cgatgcctct aatgggattt
     7381 gctgggaatt ggaaccacga accaatcctt gataaatggg cttgggaaga agggtcaaga
     7441 tcaaaaacac tgggaggtta tgatgatgat ggtaaaccga aaattccagg aaccttaaat
     7501 aagggaattg gtggagaaca tggtatagat aaatttaatc cagcaggagt tatacaaaat
     7561 agaaaagata aaaatacaac atccctggat caaaatccag aattatttgc tttcaataac
     7621 gaggggatca acgctccatc atcaagtggt tctaagattg ctaacattta tcctttagat
     7681 tcaaatggaa atcctcaaga tgctcaactt gaaagaggat taacaccttc tccacttgta
     7741 ttaagaagtg cagaagaagg attgatttca atagtaaata caaataaaga gggagaaaat
     7801 caaagagact taaaagtcat ttcgagagaa cactttatta gaggaatttt aaattctaaa
     7861 agcaatgatg caaagggaat caaatcatct aaactaaaag tttggggtga cttgaagtgg
     7921 gatggactca tctataatcc tagaggtaga gaagaaaatg caccagaaag taaggataat
     7981 caagatcctg ctactaagat aagaggtcaa tttgaaccga ttgcagaagg tcaatatttc
     8041 tataaattta aatatagatt aactaaagat tacccatggc aggtttccta tattcctgta
     8101 aaaattgata acaccgcccc taagattgtt tcggttgatt tttcaaatcc tgaaaaaatt
     8161 aagttgatta caaaggatac ttatcataag gtaaaagatc agtataagaa tgaaacgcta
     8221 tttgcgagag atcaaaaaga acatcctgaa aaatttgacg agattgcgaa cgaagtttgg
     8281 tatgctggcg ccgctcttgt taatgaagat ggagaggttg aaaaaaatct tgaagtaact
     8341 tacgcaggtg agggtcaagg aagaaataga aaacttgaca aagacggaaa taccatttat
     8401 gaaattaaag gtgcgggaga tttaagggga aaaatcattg aagtcattgc attagatggt
     8461 tctagcaatt tcacaaagat tcatagaatt aaatttgcta atcaggctga tgaaaagggg
     8521 atgatttcct attatctagt agatcctgat caagattcat ctaaatatca aaagcttggc
     8581 gagattgcag aatctaaatt taaaaattta ggaaatggaa aagagggtag tctaaaaaaa
     8641 gatacaactg gggtagaaca tcatcatcaa gaaaatgaag agtctattaa agaaaaatct
     8701 agttttacta ttgatagaaa tatttcaaca attagagact ttgaaaataa agacttaaag
     8761 aaactcatta aaaagaaatt tagagaagtt gatgatttta caagtgaaac tggtaagaga
     8821 atagaggaat acgattataa atacgatgat aagggaaata ttattgctta tgacgatggt
     8881 agtgccttac aatatgaaac tgaaaaactt gacgaaataa aatcaaaaat ttatggtgtt
     8941 ctaagcccat ctaaagatgg acactttgaa attcttggaa agataagcaa tgtttctaaa
     9001 aatgccaagg tatattatgg aaatagctat aaatcgatag aaatcaaagc gactaagtat
     9061 gattcacatt caaaaacgat gatatttgat ttatacgcta atattaatga tattgtagat
     9121 ggattagctt ttgctggaga tatgagatta tttgttaaag atgacaatca aataaaagct
     9181 gaaactaaga ttagaatgcc tgaaaaaaat aaggaaacta aagcagaata tccctatgta
     9241 tcaagttatg ggaatgtaat cgaattagga gaaggagatc tttcaaagaa caaaccagac
     9301 aatttaacta aaatggaatc tggtaaaatc tattctgatt cagaaaaaca acaatatctg
     9361 ttaaaggata acatcattct aagaaaaggc tatgcactaa aagtgactac ctataatcct
     9421 ggaaaaacgg atatgttaga aggaaatgga gtctatagca aggaagatat agcaaaaata
     9481 caaaaggcca atcctaatct aagagtcctt tcagaaacaa caatttatgc tgatagtaga
     9541 aatgttgaag atggaagaag tacccaagct gtattaatgt cggctttgga cggctttaac
     9601 attataaggt atcaagtgtt tacatttaaa atgaacgata aaggggaagc tatcgataaa
     9661 gacggaaatc ttgtgacaga ttcttctaaa cttgtattat ttggtaagga tgataaagaa
     9721 tacactggag aggataagtc caatgtagaa gctataaaag aagatggctc catgttattt
     9781 attgatacca aaccagtaaa cctttcaatg gataagaact actttaatcc atctaaatct
     9841 aataaaattt atgtacgaaa tccagaattt tatttaagag gtaagatttc tgataagggt
     9901 ggttttaact gggaattgag agttaatgaa tcggttgtag ataattattt aatctacgga
     9961 gatttacaca ttgataacac tagagatttt aatattaagc tgaatgttaa agacggtgac
    10021 atcatggact ggggaatgaa agactataaa gcaaacggat ttccagataa ggtaacagat
    10081 atggatggaa atgtttatct tcaaactggc tatagcgatt tgaatgctaa agcagttgga
    10141 gtccactatc agtttttata tgataatgtt aaacccgaag taaacattga tcctaaggga
    10201 aatactagta tcgaatatgc tgatggaaaa tctgtagtct ttaacatcaa tgataaaaga
    10261 aataatggat tcgatggtga gattcaagaa caacatattt atgtaaatgg aaaagaatat
    10321 acatcatttg atgatattaa acaaataaca gacaagacac taaacattaa gattgttgta
    10381 aaagattttg caagaaatac aaccgtaaaa gaattcattt taaataaaga tacgggagag
    10441 gtaagtgaat taaaacctca tagggtaact gtgaccattc aaaatggaaa agaaatgagt
    10501 tcaacgatag tgtcggaaga agattttatt ttacctgttt ataagggtga attagaaaaa
    10561 ggataccaat ttgatggttg ggaaatttct ggtttcgaag gtaaaaaaga cgctggctat
    10621 gttattaatc tatcaaaaga tacctttata aaacctgtat tcaagaaaat agaggagaaa
    10681 aaggaggaag aaaataaacc tacttttgat gtatcgaaaa agaaagataa cccacaagta
    10741 aaccatagtc aattaaatga aagtcacaga aaagaggatt tacaaagaga agatcattca
    10801 caaaaatctg attcaactaa ggatgttaca gctacagttc ttgataaaaa caatatcagt
    10861 agtaaatcaa ctactaacaa tcctaataag ttgccaaaaa ctggaacagc aagcggagcc
    10921 cagacactat tagctgccgg aataatgttt atagtaggaa tttttcttgg attgaagaaa
    10981 aaaaatcaag attaagacaa aagctataga aaaaaatggt ttatgtactg agattagata
    11041 gtgaggtgat gacatagttt tgtgaaaaca gccatttata actcaattat ttagtttact
    11101 tcactattga tactatttgg agttattaat ggacttagtt tagataacta atgaattgat
    11161 tgcaagggtt agtattgaca atattggtca tattgattag aaaatagagt ctatcaaaat
    11221 ttaaaggcta atagaggtga tgagacaatt tcaaggaatt aagtagcgtt tggttgctta
    11281 attccttttt atttggaagg aagtttttcg taaccgccca ataacgaagt ctattggacg
    11341 gttacgatat gatcactgac ttcgtcagtc ttatctacaa cctcaaaact gtgttttgag
    11401 caacctgcgg ctagcttcct agtttactct ttgattttca ttgagtatta gaacagcaaa
    11461 aatgcttgga gtatttgttt gtgtgtttgt ttttatataa caaactataa acaaaacaaa
    11521 aatataaaaa aagagacaaa aaagaacaga aagtaattga caacg
//
LOCUS       DAVLXH010000059        10939 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00028199
            SAMN33607166-rid17955573.denovo.059, whole genome shotgun sequence.
ACCESSION   DAVLXH010000059 DAVLXH010000000
VERSION     DAVLXH010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607166
            Sequence Read Archive: SRR23725544
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10939)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10939)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721421.1
            Genome Coverage       :: 115x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:42:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,210
            CDSs (total)                      :: 2,161
            Genes (coding)                    :: 2,023
            CDSs (with protein)               :: 2,023
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 73 of 138
            Pseudo Genes (incomplete)         :: 60 of 138
            Pseudo Genes (internal stop)      :: 40 of 138
            Pseudo Genes (multiple problems)  :: 31 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10939
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607166-rid17955573.denovo.059"
                     /strain="AUSMDU00028199"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1349"
     gene            1..958
                     /locus_tag="VYO11_001803"
                     /pseudo
     CDS             1..958
                     /locus_tag="VYO11_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(1086..2048)
                     /gene="cbpF"
                     /locus_tag="VYO11_001804"
                     /pseudo
     CDS             complement(1086..2048)
                     /gene="cbpF"
                     /locus_tag="VYO11_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771060.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpF"
     gene            complement(2067..2892)
                     /gene="cbpG"
                     /locus_tag="VYO11_001805"
                     /pseudo
     CDS             complement(2067..2892)
                     /gene="cbpG"
                     /locus_tag="VYO11_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001100143.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpG"
     gene            complement(2973..3212)
                     /locus_tag="VYO11_001806"
     CDS             complement(2973..3212)
                     /locus_tag="VYO11_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000754500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1596319.1"
                     /translation="MKKTVYKKLGISIIASTLLASQLSTVSALSVISSTGEEYEVSET
                     LEKGPGSNDSSLSEISPTYGSYYQKQSEVLSVMMI"
     gene            complement(3362..3628)
                     /locus_tag="VYO11_001807"
                     /pseudo
     CDS             complement(3362..3628)
                     /locus_tag="VYO11_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060522.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
     gene            complement(3653..3961)
                     /locus_tag="VYO11_001808"
     CDS             complement(3653..3961)
                     /locus_tag="VYO11_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HEV1596320.1"
                     /translation="MDWDFADTCWEKEPRKYQYVAANYLKAMQSYLKETDLPKLEQLV
                     VTKSWWDTVDILDRVVGSLVYEHPELEEIILILFENLFKPRQLYLQPQNSVLRLQISS
                     "
     gene            complement(3886..4128)
                     /locus_tag="VYO11_001809"
     CDS             complement(3886..4128)
                     /locus_tag="VYO11_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HEV1596321.1"
                     /translation="MSLADLLEELEAAKDSKKARPMEAYMRHQFSFLGIAVPERNKLY
                     KNIYQKRKKQRLSIGILQTLAGKRSLENTNMWLLTI"
     gene            complement(4129..4761)
                     /locus_tag="VYO11_001810"
     CDS             complement(4129..4761)
                     /locus_tag="VYO11_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1596322.1"
                     /translation="MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEASNGSQGIDLALE
                     LRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIVTSYLDNEKIMPVLDAGAKGYML
                     KTSSADELLHAVSKVAAGELAIEQEVSKKVEYHRNHMELHEELTARERDVLQLIAKGY
                     ENQRIADDLFISLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVGQEEF"
     gene            complement(4775..5770)
                     /locus_tag="VYO11_001811"
     CDS             complement(4775..5770)
                     /locus_tag="VYO11_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV1596323.1"
                     /translation="MKKQAYVIIALTSFLFVFFFSHSLLEILDFDWSIFLHDVEKTEK
                     FVFLLLVFSMSMTCLLVLFWRGIEELSLRKMQANLKRLLAGQEVVQVVDPDLDASFKS
                     LSGKLNLLTEALQKAENHSLAQEEEIIEKERKRIARDLHDTVSQELFAAHMILSGISQ
                     QALKLDREKMQTQLQSVTAILETAQKDLRVLLLHLRPVELEQKSLIEGIQILLKELED
                     KSDLRVSLKQNMTKLPKKIEEHIFRILQELISNTLRHAQASCLDVYLYQTDVELQLKV
                     VDNGIGFQLGSLDDLSYGLRNIKERVEDMAGTVQLLTAPKQGLAVDIRIPLLDKE"
     gene            complement(5767..6465)
                     /locus_tag="VYO11_001812"
     CDS             complement(5767..6465)
                     /locus_tag="VYO11_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein"
                     /protein_id="HEV1596324.1"
                     /translation="MRKFKIFLFIEACLLTGALILMVSEHFSRFLLILFLFLLLIRYY
                     TGKEGNNLLLVAATILFFFIVMLNPFVILAIFVAVIYSLFLLYPMMNQEKEQTNLVFE
                     EVVTVKKEKNRWFGNLHHFSSYQTCQFDDINLFRFMGKDTIHLERVILTNHDNVIILR
                     KMVGTTKISVPVDVEVSLSVNCLYGDLTFFNQPKRALRNEHYHQETKDYLKSNKSVKI
                     FLTTMIGDVEVVRG"
     gene            complement(6543..7553)
                     /locus_tag="VYO11_001813"
     CDS             complement(6543..7553)
                     /locus_tag="VYO11_001813"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000210649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HEV1596325.1"
                     /translation="MTTNRKDEHILYALEQKSSYNSFDEVELIHSSLPLYNLDEIDLS
                     TEFAGRKWDFPFYINAMTGGSNKGREINQKLAQVAESCGILFVTGSYSAALKNPTDDS
                     FSVKSSHPNLLLGTNIGLDKPVELGLQTVEEMNPVLLQVHVNVMQELLMPEGERKFRS
                     WQSHLADYSEQIPVPIVLKEVGFGMDAKTIERAYEFGVRTVDLSGRGGTSFAYIENRR
                     SGQRDYLNQWGQSTMQALLNAQEWKDKVELLVSGGVRNPLDMIKCLVFGAKAVGLSRT
                     VLELVETYTVEEVIGIVQGWKADLRLIMCSLNCATIADLQKVDYLLYGKLKEANDQMK
                     KA"
     gene            complement(7537..8544)
                     /locus_tag="VYO11_001814"
     CDS             complement(7537..8544)
                     /locus_tag="VYO11_001814"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000562378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HEV1596326.1"
                     /translation="MIAVKTCGKLYWAGEYAILEPGQLALIKDIPIYMRAEIAFSDSY
                     RIYSDMFDFAVDLRPNPDYSLIQETIALMGDFLAVRGQNLRPFSLKICGKMEREGKKF
                     GLGSSGSVVVLVVKALLALYNLSVDQNLLFKLTSAVLLKRGDNGSMGDLACIVAEDLV
                     LYQSFDRQKVAAWLEEENLATVLERDWGFFISQVKPTLECDFLVGWTKEVAVSSHMVQ
                     QIKQNINQNFLSSSKETVVSLVEALEQGKAEKVIEQVEVASKLLEGLSTDIYTPLLRQ
                     LKEASQDLQAVAKSSGAGGGDCGIALSFDAQSTKTLKNRWADLGIELLYQERIGHDDK
                     S"
     gene            complement(8531..9484)
                     /gene="mvaD"
                     /locus_tag="VYO11_001815"
     CDS             complement(8531..9484)
                     /gene="mvaD"
                     /locus_tag="VYO11_001815"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HEV1596327.1"
                     /translation="MDREPVTVRSYANIAIIKYWGKKKEKEMVPATSSISLTLENMYT
                     ETTLSPLPANVTADEFYINGQLQNEVEHAKMSKIIDRYRPAGEGFVRIDTQNNMPTAA
                     GLSSSSSGLSALVKACNAYFKLGLDRSQLAQEAKFASGSSSRSFYGPLGAWDKDSGEI
                     YPVETDLKLAMIMLVLEDKKKPISSRDGMKLCVETSTTFDDWVRQSEKDYQDMLIYLK
                     ENDFAKIGELTEKNALAMHATTKTASPAFSYLTDASYEAMDFVRQLREKGEACYFTMD
                     AGPNVKVFCQEKDLEHLSEIFGQRYRLIVSKTKDLSQDDCC"
     gene            complement(9466..10344)
                     /gene="mvk"
                     /locus_tag="VYO11_001816"
     CDS             complement(9466..10344)
                     /gene="mvk"
                     /locus_tag="VYO11_001816"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HEV1596328.1"
                     /translation="MTKKVGVGQAHSKIILIGEHAVVYGYPAISLPLLEVEVTCKVVP
                     AESPWRLYEEDTLSMAVYASLEYLDITEACIRCEIDSAIPEKRGMGSSAAISIAAIRA
                     VFDYYQADLPHDVLEILVNRAEMIAHMNPSGLDAKTCLSDQPIRFIKNVGFTELEMDL
                     SAYLVIADTGVYGHTREAIQVVQNKGKDALPFLHALGELTQQAEVAISQKDAEGLGQI
                     LSQAHLHLKEIGVSSPEADFLVETTLSHGALGAKMSGGGLGGCIIALVTNLTHAQELA
                     ERLEEKGAVQTWIESL"
     gene            complement(10466..10795)
                     /locus_tag="VYO11_001817"
     CDS             complement(10466..10795)
                     /locus_tag="VYO11_001817"
                     /inference="COORDINATES: protein motif:HMM:NF024736.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV1596329.1"
                     /translation="MTRKAYDTDLNDQEWAKIEPYFCKHRTYKWPKRVLVNETLYVTK
                     TGCQWRMLPHDFPLYLMVWSFFHRSMTTGWFQVNGRWYYAYSSGALAVNTTVDGYSVN
                     YNGEWVR"
BASE COUNT         3255 a         2522 c         1939 g         3223 t
ORIGIN      
        1 gagacctgaa gagagaacag aattagaacg tcttcaagca gaaaatgagt acctgagagc
       61 ggagaatgcc atcctaaaaa agttaagaga actccgattg aaggaggaaa aagagaaaga
      121 agaaagacag aaattgttca agaattaatg actgagtttt cgttagatct tcttctaaaa
      181 gccattaaac tagctcgttc gacctactac tatcacttga aacagctaga taaaccagat
      241 aaggaccaag agcttaaagc tgaaattcaa tccattttta tcgaacacaa gggaaattat
      301 gcttatcgtc ggatttattt agaactaaga aatcgtggtt atctggtaaa ttataaaaga
      361 gttcaaggct tgatgaaagt actcaattta caagctaaaa tgcgacagaa acgaaaatgg
      421 caagaaggca gagaatctca ttcaaggcca atttgaaggc tctaaaacaa tggaaaagtg
      481 ctacacagat gtgacagaat ttgccattcc agcaagtact caaaagcttt acttatcacc
      541 agttttagat ggctttaaca gcgaaattat cgcctataat ctttcaactt cacccaactt
      601 agaacaagta caaacaatgt tggaacaggc attcacagag aagcactacg agaatacgat
      661 tctccatagt gaccaaggct ggcaatacca acacgattct tatcatcagt tcctagagag
      721 taagggaatt caagcatcca tgtcacgtaa gggtaacagc ccagacaatg gtatgatgga
      781 gtccttcttt gggattctga aatcggaaat gttttacggt tatgagaagt cgtttcagtc
      841 gtttaagcaa ttggaacaag ctattgtaga ctatattgat tactacaaca ataaacgaat
      901 taaggtaaaa ctaaaaggac ttagccctgt gcaatacaga actaaatcct tcggataaat
      961 tatttgtcta actttttggg gtcagtacag aaaaactttg atactatgcg ttttttgatt
     1021 gtgaagactt ttatccacct attatacaaa gttaagtatc catcacagtt tacaattagc
     1081 cttcattact taacccattc accattatag tttaagtagt aaccacctac tgtggtatta
     1141 acagctaaag cacctgaatc ataggcatag taccagttac cattgacttg gaaccagcct
     1201 gttttcatat ctccattact tgcatttaga tagtaccaag tcgaaccttc ctgataccaa
     1261 ccagttgcca tagctcctga tgaacggaga tagtaccact tgttaccaag gtattgccag
     1321 ccagttctca tatcaccatt ttcagtatct aaatagtacc aagttgagcc ttccttatac
     1381 caaccagttt gcataatgcc agttgttgga tctagatagt accatggagc tgcttttagc
     1441 ttctcttcat cataggtaag agggtaatcc ttaacccaac cacgtgctag ctctccaacc
     1501 gtcaatctgt tgatgcgcga atcaaagcca ccatccttct gtaaataata ccaatgaccc
     1561 tcttcgtaaa tccaaccagt ttttaaagta tgataactac gctgatcttc aaaataatag
     1621 actcatttct ctgctgggct atcatattct tccccatgat gtttgttggt attcgtagca
     1681 gtttttgctt ctaaaacttg cttgccaaca aattcttgta atacaccatc ttgaccaaaa
     1741 taaaaccaat ctggtctaag agaaatctct attcttggag aaggaccaat cgtaaccccc
     1801 ttgtgtggag caggtatata ttgccagccg acaaccatct ctccggataa aggatcaaaa
     1861 taatagtact tcccatctat cactctccag taggtttctt ttagatcccc ctttttgtag
     1921 taggttctac cattttcttg gacaaactgc catccttcag aatcatctgc aaatactgta
     1981 ctggtcccta gcaaaccgaa gaaaaatgtg gctagtgcga cttgcatcat ttttttcaaa
     2041 agcttcattt tatatatcct ccaacattaa atccactcac cagatgaagc gaagttataa
     2101 actttaccat cgatagtttg gctacctgta accattgctc catttgaatt gagataatac
     2161 cattttccat ttactttttg ccaatctgta agcatcttac cggaactgtc taaataatac
     2221 caagtatcat ttatctcctg ccaacccgtt tgtttatcat gttgtctata atggtaccaa
     2281 ctaccattta ttttcttcca tccttcaaga gagtaacctt taagaaccga ataaataaat
     2341 aaatggcaaa tttcgttcat ttaatttaac tgcactgtta atttgattag ctccatctcc
     2401 taaagtatgc actcctacta cacggtgact agcatcataa actgtagatc cactagaccc
     2461 ctctaaagta tcaacttggt aatccaagaa catgccatca tcacttaaaa cttgtttttt
     2521 atctgtatac atttgatgaa ctttaaaatt atatgatgga tagcctgtga tagtcacagt
     2581 tattcctgtc aaattttttt gactagtagg aagacccaaa gtccctaatt ttgcaccaat
     2641 gggctcttct agaattaata aagccaagtc atattccctt gcatccttag aatttaaatt
     2701 tctaaattcc ttcaaataac gaacttcctt tactttgatc tttccaaatg gttcttgact
     2761 tggactaaca gccggaagaa cataaatatc atccgcttct ttcccatagt catgtctgta
     2821 gtagttgtga gccgctgtaa ttaacacatt atctttaata aaattcgcac ttcccctccc
     2881 ttctacattc attccatcgg ctactccata atacttagat aaaaccatag ctgaagtcga
     2941 atacggatac tgtaaagtat tatcaatttt aatcaaatca tcattaccga taatacttct
     3001 gattgctttt ggtagtatga accatatgtt ggtgaaatct cagataatga agaatcatta
     3061 gatcctggac ctttttctag tgtctcactt acctcatatt cttcacccgt actagaaata
     3121 acactcaaag cagatactgt cgataactgg ctagccaata aagtactcgc aataattgaa
     3181 atacccaatt ttttataaac agttttcttc attattgtat cctcctaatg taattatagc
     3241 gtactattct aaatttctta atctactata gaatcaagaa atctaccacc ttctttaaat
     3301 accctccatt atcacataaa caggtaaact tttcaattaa tgactgcgct tttcaatcac
     3361 gctagaggta cttacttgct tctttgatac taagttcagc cattctttcc ttgtttttct
     3421 caataaagca tgttacccaa gtgggattcg ttttggagta gtctcgcaga gtccagccaa
     3481 tggctttatt gataaaaaat tctgtttggt tcaagttatg aagtagaatc ttttccatta
     3541 attgagtatt ggtcttctct tttcttaaca actggtggtc aatagcgaca cgtctcagcc
     3601 agatattatc tgataggctc cattttatac tcaatgaaaa tcaaagagca aactaggaag
     3661 atatctgcaa cctcaaaaca ctgttttgag gttgcagata gagctgacgt ggtttgaaga
     3721 gattttcgaa gagtattaag attatttctt ctagttcagg gtgttcatac accaaactcc
     3781 ctactactcg atctaggata tctaccgtgt cccaccagga ttttgtcacg actaactgct
     3841 ctagcttagg caaatcggtt tcctttagat aagactgcat tgctttcaaa tagttagcag
     3901 ccacatattg gtattttcta ggctcctttt cccagcaagt gtctgcaaaa tcccaatcga
     3961 taatctttgt ttttttcgct tctggtaaat atttttatag agtttatttc tttcaggcac
     4021 cgcaatacct agaaaagaaa attgatggcg catataggct tccatgggcc ttgctttttt
     4081 agagtctttt gctgcttcta gctcctcaag taaatctgct aaactcatct aaaactcctc
     4141 ttgccccacc aaatggtgct gaaaggcata gacagccgcc tgggtacgat cgctgacttc
     4201 aagtttggca agaatattgg acacgtgggt cttgaccgtc ttgagagaga taaagaggtc
     4261 atctgcgatg cgctgatttt cgtagccctt ggcgatgagt tggagaacat ctcgctcacg
     4321 cgcagtcaat tcttcatgaa gttccatatg attgcggtgg tattcaacct tcttgctaac
     4381 ctcttgctca atggccagct cgccagcagc taccttactg acggcatgaa gcaattcatc
     4441 tgcactagaa gtcttgagca tatagccttt ggcaccagca tctaagactg gcatgatttt
     4501 ttcattgtcc aaataagagg tcacaatcaa aatcttggct tcaggccatt ctttaaggat
     4561 tgctaaggtc gcgtcaatcc cattcatctc aggcatgaca atatccatga caatgacatc
     4621 tggacgcagt tccaaggcca agtcaatccc ttgagacccg ttggacgcct cacccacaac
     4681 ttctacatcg tcttggaggt caaagtagct tttcaagccc aaacggacca tttcatggtc
     4741 atctactagt aaaattttca tctttactcc tttatcattc cttatctaac aggggaatac
     4801 ggatatcaac tgccagccct tgcttgggag ctgttaataa ctgaaccgtc cctgccatat
     4861 cttcaacccg ctccttgata tttcgcagtc cataactcaa gtcgtctaag ctccctaact
     4921 ggaaaccaat cccattgtcc accaccttca gttgcaattc aacatctgtc tgatagaggt
     4981 agacatctag gcaagatgcc tgggcatggc ggagcgtatt gctaatcaac tcttgcagga
     5041 tacggaaaat atgctcctcg attttcttag gcaatttcgt catattctgc ttgagactaa
     5101 ccctaagatc actcttgtcc tcaagctctt ttaagagaat ttgaatccct tctatcaagc
     5161 tcttctgctc cagttcaact ggtcgcaaat gcaagagcaa aacccgcaaa tccttctggg
     5221 ctgtttctaa aatagctgtg acactctgca actgggtctg catcttttct ctatccaatt
     5281 tcaaagcctg ctgactgata cccgataaaa tcatgtgggc cgcaaacaac tcctgactga
     5341 ctgtatcgtg caaatcccga gcaattcgct tccgttcctt ctcgatgatt tcctcttcct
     5401 gagcaaggct atgattttca gctttttgaa gagcctctgt caaaaggtta agtttacctg
     5461 ataaggactt gaaactggca tccaaatctg gatctacaac ctgaactact tcttgccctg
     5521 ccaataaacg cttgagatta gcctgcattt ttcttagaga aagctcttcg atccctcgcc
     5581 aaaacaggac taagagacag gtcatggaca tgctgaaaac caacaataaa aagacaaatt
     5641 tttctgtttt ttcgacatcg tgcaaaaaga tagaccagtc aaaatcaagt atttccagca
     5701 agctatggga gaaaaaaaag acaaacagga aggaggtgag agcgataatg acataggctt
     5761 gttttttcat cctctaacca cctccacatc accaatcata gtggtcaaga aaatcttgac
     5821 actcttgtta ctcttgagat agtcttttgt ttcttgatga tagtgttcat tgcggagggc
     5881 tcgcttgggc tggttgaaaa aagtcaaatc cccatagaga cagttaacgc tgagactgac
     5941 ttccacatct acaggtacgc tgattttggt cgttcctacc atctttctga ggataatgac
     6001 attgtcatga ttggttaaga tgaccctctc cagatgaata gtgtccttgc ccatgaagcg
     6061 aaagagattg atatcatcga attggcaagt ctggtagctt gaaaaatgat gaagatttcc
     6121 aaaccaacga tttttctcct tcttaaccgt cacgacctct tcaaaaacca aattggtctg
     6181 ctctttttcc tggttcatca tcgggtaaag aagaaagagg ctatagataa ccgcaacaaa
     6241 aatagctaga atcacaaaag gattgagcat aacgatgaaa aagaagagaa tggttgccgc
     6301 tactaaaaga agattatttc cctctttacc agtgtagtag cgaatcaaaa gcaaaaagag
     6361 gaatagtatc agcagaaaac gcgaaaaatg ctctgatacc atcaaaatca gagctcctgt
     6421 cagaagacag gcttcgataa ataaaaagat tttaaatttt ctcataggtt catcctctcc
     6481 cttctatttt atcacaattc aaaaaagtca cctcagtctg aggatggaaa aaaaggcgct
     6541 ggttacgcct ttttcatctg atcatttgct tcttttaatt ttccataaag aagatagtct
     6601 actttttgta gatctgctat ggtggcacag ttaagggaac acataatcaa gcgtagatct
     6661 gctttccagc cttggacaat gccaatcact tcttcaactg tgtaggtttc aaccaattcc
     6721 agaacggttc gtgacaatcc cacagcctta gcaccaaaaa ccaagcactt aatcatatcc
     6781 agcggattcc gaacccctcc actaaccaag agttcgacct tatctttcca ttcttgggca
     6841 ttgagaaggg cctgcatggt agactgaccc cattgattga ggtaatcacg ctggccacta
     6901 cgacggtttt cgatataggc aaagctggtg ccaccacgac ccgataggtc cactgtacga
     6961 acaccgaatt cataggctct ttcgattgtc ttggcatcca ttccaaagcc cacttccttg
     7021 aggacaatag gaacgggaat ttgctcgcta taatctgcta gatgcgattg ccagcttcta
     7081 aacttccttt ctccctcggg catgagtaat tcctgcatga cattgacatg cacttgcaat
     7141 agaacaggat tcatctcttc tacagtctga agtcctaact cgacaggctt gtccaatcca
     7201 atattggttc caaggaggag attgggatga ctagacttga cagaaaaaga atcatccgtt
     7261 ggatttttga gggctgcgct ataagaaccc gttacaaata aaataccaca ggattccgcc
     7321 acctgagcca gcttttgatt gatttctctt cccttattac ttccaccagt catggcattg
     7381 atataaaaag gaaagtccca ctttcgacca gcaaactctg tcgaaagatc gatttcatcc
     7441 agattgtaaa gaggcaagga agaatgaatc agctccacct catcaaagct attataggaa
     7501 cttttctgct caagggcata gaggatatgc tcgtccttac gatttgtcgt catgtcctat
     7561 cctttcttga tataagagct caatccccag atcggcccaa cgatttttta aggttttggt
     7621 tgattgcgca tcaaaactca aggcgatgcc acagtcacca ccaccagcac cactactctt
     7681 ggcaacggcc tgcaaatctt gactggcttc tttcaactgt ctaagcaaag gcgtgtaaat
     7741 atctgtactc aagccttcta aaagcttgct ggctacttct acttgctcga taactttttc
     7801 ggctttcccc tgctccaagg cttcgaccaa agaaaccacc gtttcttttg aggaacttaa
     7861 aaaattttga ttgatatttt gcttgatttg ctggaccatg tgactcgata cagccacttc
     7921 cttggtccat cccactaaga aatcacattc taaagttggt ttcacttgtg agataaaaaa
     7981 tccccaatca cgctccagaa ctgtcgccaa gttttcttct tctaaccaag cagccacctt
     8041 ctggcgatca aatgactggt agagaaccaa atcctctgcc acaatacagg caaggtcgcc
     8101 catggaacca ttgtctcctc gcttgagcaa gacagcgcta gtcagcttga acaagagatt
     8161 ctgatcaacc gaaagattat agagagccag taaagccttg acaaccaaga caacgacgct
     8221 gccactagaa cctagaccaa actttttccc ttctcgttcc attttgccac agatttttag
     8281 ggaaaaaggt cttaaattct gaccgcgaac agcgaggaag tctcccatca aagcaatcgt
     8341 ttcttgaatc aagctgtagt caggattagg ccttaagtcc actgcgaaat caaacatatc
     8401 tgaatagata cggtagctgt cagaaaaagc aatttcagcc ctcatataga tgggaatatc
     8461 ctttatcaaa gctaactgcc ctggctctaa aatagcatat tcacctgccc aatagagttt
     8521 tccgcaagtt ttaacagcaa tcatcttgac tcaaatcctt tgtttttgac acaatcaagc
     8581 gataacgctg accgaaaatt tctgataaat gctccaagtc tttctcctga cagaagacct
     8641 taacattggg accagcatcc atggtaaagt agcaggcctc tcctttctca cgaagctggc
     8701 gaacaaagtc catagcctca taagaggcat ccgtcagata agaaaaggct ggactagcag
     8761 tctttgtcgt agcatgcata gccagggcat ttttctccgt taattctcca atcttggcaa
     8821 aatcattttc cttgagataa atcagcatat cctgatagtc cttctcagac tgacgaaccc
     8881 agtcgtcgaa agtcgtcgag gtttccacac aaagtttcat cccgtcacgg ctagagattg
     8941 gttttttctt gtcctctagc accaacataa tcatagctag tttcaagtct gtctctacag
     9001 ggtaaatttc tccactatcc ttatcccagg ctcctagtgg tccataaaaa ctccgagaag
     9061 aagagcctga ggcaaacttg gcttcctgcg ctaactgact tctatccaat ccaagcttga
     9121 aataagcatt acaagccttg accagggcgg acaaaccact agaacttgag gacaggcccg
     9181 ctgccgtagg catattgttt tgagtatcga tacggacaaa gccctcacca gctggacgat
     9241 aacggtcaat aatcttactc atcttggcat gctcgacctc attttgtagc tgaccattga
     9301 tgtaaaattc gtcagctgtt acattggctg gtaaaggcga caaggtcgtc tctgtataca
     9361 tattttccaa agttagagaa atactgctag tagcaggcac catctctttt tcttttttct
     9421 ttccccaata tttgataata gcaatatttg cgtaggaacg tactgttaca ggctctctat
     9481 ccatgtctga acagctcctt tctcttctaa tctttctgct agttcttgtg cgtgtgtcaa
     9541 attggttacc aaggctatga tacaacctcc tagcccacca ccgctcatct tggcacccag
     9601 agcaccatgg ctaagagtcg tttcaaccaa aaagtctgcc tcagggctac tgactccaat
     9661 ttcttttaaa tgtaaatgcg cttgactgag gatttgtccc agtccttcag catctttttg
     9721 tgaaatcgca acttctgctt gctgggttaa ttctcccaag gcatgcaaaa acggtagggc
     9781 atccttgccc ttattttgaa ccacttggat ggcttcacga gtatgaccat aaacacccgt
     9841 atcggcaatc accaaatagg cggataaatc catctcaagt tctgtaaatc ctacgttctt
     9901 gataaagcga ataggttggt cactgagaca ggtcttagca tccaaaccac taggattcat
     9961 atgggcaatc atttcagctc gattgaccaa gatttctagt acatcatgag gcagatcagc
    10021 ctgatagtag tcaaataccg cacgaatggc cgctatgctg atagccgctg acgaacccat
    10081 cccccgtttc tcagggatag ccgagtcaat ctcacaacga atgcaggctt ctgtgatatc
    10141 caaatactcc agtgaggcat aaaccgccat ggacaaggta tcctcctcat aaaggcgcca
    10201 aggactctct gcaggaacta ccttacaggt cacctccacc tccaaaagag gcagggaaat
    10261 ggcaggataa ccgtaaacga ccgcatgttc ccctattaaa attatcttac tatgtgcctg
    10321 accgacacca actttttttg tcattttttc cttttactag acgaaaaaac gtcttatttt
    10381 tcatacaagt attaattctt tcctatctat tttattatat tttcacaaaa aaagcgattg
    10441 tttccattca caatcgcttc tttcattacc gaacccattc accattataa ttgacagaat
    10501 agccatctac agtcgtattc actgccaagg cacctgagct ataagcgtag taccatctgc
    10561 cattgacctg gaaccaacct gtcgtcatag aacgatgaaa gaaactccat accattaagt
    10621 aaagaggaaa gtcatgaggg agcatgcgcc attgacaacc tgttttagtg acgtacaaag
    10681 tttcattaac aagtactcgt ttcggccatt tataggtgcg gtgtttgcag aaatagggtt
    10741 caatcttcgc ccattcttga tcgtttaaat cagtatcata tgctttgcgt gtcataactc
    10801 tagtttaaca tttttttgtg aatacaggtt ctaaataatc gaccacgaaa atttcttaag
    10861 tggaaaacgc cttatgaagt atgctacggg aaacttatgc acttaatttg acaactcaat
    10921 atgtaaaaat atatactat
//
LOCUS       DAVLXH010000060        10695 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00028199
            SAMN33607166-rid17955573.denovo.060, whole genome shotgun sequence.
ACCESSION   DAVLXH010000060 DAVLXH010000000
VERSION     DAVLXH010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607166
            Sequence Read Archive: SRR23725544
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10695)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10695)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721421.1
            Genome Coverage       :: 115x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:42:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,210
            CDSs (total)                      :: 2,161
            Genes (coding)                    :: 2,023
            CDSs (with protein)               :: 2,023
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 73 of 138
            Pseudo Genes (incomplete)         :: 60 of 138
            Pseudo Genes (internal stop)      :: 40 of 138
            Pseudo Genes (multiple problems)  :: 31 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10695
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607166-rid17955573.denovo.060"
                     /strain="AUSMDU00028199"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1349"
     gene            complement(66..1490)
                     /locus_tag="VYO11_001818"
     CDS             complement(66..1490)
                     /locus_tag="VYO11_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent glyceraldehyde-3-phosphate
                     dehydrogenase"
                     /protein_id="HEV1596330.1"
                     /translation="MTRYQNLVNGKWKSSEQEITIYSPINQEELGTVPAMTQTEADEA
                     MQAARAALPAWRALSAIERAAYLHKTAAILERDKEKIGTILAKEVAKGIKAAIGEVVR
                     TADLIRYAAEEGLRITGQAMEGGGFEAASKNKLAVVRREPVGIVLAIAPFNYPVNLSA
                     SKIAPALIAGNVVMFKPPTQGSISGLLLAKAFEEAGIPAGVFNTITGRGSEIGDYIIE
                     HKEVNFINFTGSTPIGERIGRLAGMRPIMLELGGKDAALVLEDADLEHAAKQIVAGAF
                     SYSGQRCTAIKRVIVLESVADKLATLLQEEVSKLTVGDPFDNADITPVIDNASADFIW
                     GLIEDAQEKEAQALTPIKREGNLLWPVLFDQVTKDMKVAWEEPFGPVLPIIRVASVEE
                     AIAFANESEFGLQSSVFTNDFKKAFEIAEKLEVGTVHINNKTQRGPDNFPFLGVKGSG
                     AGVQGIKYSIEAMTNVKSIVFDVK"
     gene            complement(2035..4314)
                     /gene="pulA"
                     /locus_tag="VYO11_001819"
     CDS             complement(2035..4314)
                     /gene="pulA"
                     /locus_tag="VYO11_001819"
                     /EC_number="3.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pullulanase"
                     /protein_id="HEV1596331.1"
                     /translation="MYNYPMRIHYHRKNGEYDTCSFVKSQDQRIDLLTYKEDYFGALF
                     SFEHPSSHVIESLNFVVHTGQTSKEYSIRFNHYPLLTEVWILEGDDRIYYSENPAIAS
                     PFYKNQNPFAFDKAINSASFDHHWGYQGELGCRVEDNQAHFSLWSPTATEVQVVVYES
                     AANDAPVWKTFEMKRGNSYSYNHKDNTIGVWSLDVEEDLVGKTYQYQVQFPHHQTLTR
                     DPYTIATSPDGKRSAILSHVEKQVENFEVKHGSEATWRLENPCKAVICEMHIRDLTKS
                     PTSGVDEHLRGTFLGAAQAGTVNQYGQSTAFDYIKKLGYNYVQLQPIADRHKEYDEDG
                     NVTYNWGYDPQNYNAPETSFSTNPDDPAQVIRDLKVMVQAYHDAGIGVIMDVVYNHTF
                     SVVDAPFQTTVPDYYYRMNPDGTFQNGTGVGNETASEHEMFRKYMIDSLLYWVQEYNI
                     DGFRFDLMGIHDVKTMQMIRQSLDEIDSNIILYGEGWDMGTGLPPYDKAKKDNAYQMP
                     NIGFFNDNQRDAVKGGEVYGAIKSGFVSGAATEPILAKAILGSRELGTYTHPNQVLNY
                     VEAHDNYNLHDLLATLHPDQSSEQIMRKVETATAMNLLMQGMAFMEIGQEFGRTKLVA
                     TGENGELTHDDRERAMNSYNAPDSVNQVNWNLINERQDSIEFIRQVIRLKTKTGAFSY
                     SSYDEIYHHVFVHSAIEHSGCLIYEVHGKEHLLVVVNAKSEPYQFENAGNLAMLVTNS
                     RSKEDNVLNDISLAVLSVL"
     gene            complement(4426..6384)
                     /gene="ligA"
                     /locus_tag="VYO11_001820"
     CDS             complement(4426..6384)
                     /gene="ligA"
                     /locus_tag="VYO11_001820"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HEV1596332.1"
                     /translation="MNKRMNELVALLNRYATEYYTSDNPSVADSEYDRLYRELVELET
                     AYPEQVLADSPTHRVGGKVLDGFEKYSHQYPLYSLQDAFSREELDAFDARVRKEVAHP
                     TYICELKIDGLSISLTYEKGILVAGVTRGDGSIGENITENLKRVKDIPLTLPEELDIT
                     VRGECYMPRASFDQVNQVRQENGEPEFANPRNAAAGTLRQLDTAVVAKRNLATFLYQE
                     ASPSTRDSQEKGLKYLEQLGFVVNPKRILAENIDEIWNFIQEVGQERENLPYDIDGVV
                     IKVNDLASQEELGFTVKAPKWAVAYKFPAEEKEAQLLSVDWTVGRTGVVTPTANLTPV
                     QLAGTTVSRATLHNVDYIAEKDIRKDDTVIVYKAGDIIPAVLRVVESKRVSEEKLDIP
                     TNCPSCNSDLLHFEDEVALRCINPRCPAQIMEGLIHFASRDAMNITGLGPSIVEKLFA
                     ANLVKDVADIYRLQEEDFLLLEGVKEKSAAKLYQAIQASKENSAEKLLFGLGIRHVGS
                     KASQLLLQYFHSIENLYQADSEEVASIESLGGVIAKSLQTYFATEGSEILLRELKETG
                     VNLDYKGQTVVADAALSGLTVVLTGKLERLKRSEAKSKLESLGAKVTGSVSKKTNLVV
                     VGADAGSKLQKAQELGIQVRDEAWLESL"
     gene            complement(6477..7656)
                     /locus_tag="VYO11_001821"
                     /pseudo
     CDS             complement(6477..7656)
                     /locus_tag="VYO11_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001083019.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
     gene            complement(7736..8599)
                     /locus_tag="VYO11_001822"
     CDS             complement(7736..8599)
                     /locus_tag="VYO11_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012291596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HEV1596333.1"
                     /translation="MEHLGKVFREFRTSGNYSLKEAAGESCSTSQLSRFELGESDLAV
                     SRFFEILDNIHVTIENFMDKARNFHNHEHVSMMAQIIPLYYSNDIAGFQKLQREQLEK
                     SKSSTTPLYFELNWILLQGLICQRDASYDMKQDDLDKVADYLFKTEEWTMYELILFGN
                     LYSFYDVDYVTRIGREVMEREEFYQEISRHKRLVLILALNCYQHCLEHSSFYNANYFE
                     AYTEKIIDKGIKLYERNVFHYLKGFALYQKGQCKEGCKQMQEAMHIFDVLGLPEQVAY
                     YQEHYEKFVKS"
     gene            complement(8602..10503)
                     /locus_tag="VYO11_001823"
     CDS             complement(8602..10503)
                     /locus_tag="VYO11_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000584877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEV1596334.1"
                     /translation="MIILQANKIERSFAGEVLFDNINLQVDERDRIALVGKNGAGKST
                     LLKILVGEEEPTSGEINKKKDISLSYLAQDSRFESENTIYDEMLHVFNNLRRTERQLR
                     QMELEMGEKSGEDLDKLMSDYDRLSENFRQAGGFTYEADIRAILNGFKFDESMWQMKI
                     AELSGGQNTRLALAKMLLEKPNLLVLDEPTNHLDIETISWLENYLVNYSGALIIVSHD
                     RYFLDKVATITLDLTKHSLDRYVGNYSRFVELKEQKLVTEAKNYEKQQKEISALEDFV
                     NRNLVRASTTKRAQSRRKQLEKMERLDKPEAGKKSANMTFQSEKTSGNVVLTVENAAV
                     GYDGEVLSQPINLDLRKMNAVAIVGPNGIGKSTFIKSIVDQIPFIKGEKRFGANVEVG
                     YYDQTQSKLTPSNTVLDELWNDFKLTPEVEIRNRLGAFLFSGDDVKKSVGMLSGGEKA
                     RLLLAKLSMENNNFLILDEPTNHLDIDSKEVLENALIDFDGTLLFVSHDRYFINRVAT
                     HVLELSENGSTLYLGDYDYYVEKKATAEMSQTEEASTSNQAKEASPVNDYQAQKESQK
                     EVRKLMRQIESLEAEIEELESQSQAISEQMLETNDADKLMELQAELDKISHRQEEAML
                     EWEELSEQV"
BASE COUNT         3205 a         2357 c         1912 g         3221 t
ORIGIN      
        1 ctataattat tattatttta tagcaaaaaa ataaaaccag gaaaacaatt tcctgatttt
       61 acacgttatt tcacatcaaa aacaatggat ttgacatttg tcatcgcttc aatgctatat
      121 ttaattcctt gcactccagc tccagaacct ttgacaccaa ggaatgggaa attatctgga
      181 ccacgctggg ttttattatt aatgtggact gtacctactt caagtttttc agcaatttca
      241 aaggcttttt tgaaatcatt tgtaaagact gatgattgaa ggccgaattc agattcgttg
      301 gcaaaggcaa tagcttcctc tacactagcc acacgaatga ttggtaaaac aggaccaaat
      361 ggctcttccc atgccacttt catatctttt gtaacttggt caaaaagcac tggccagagg
      421 agattgccct cacgtttgat tggtgtaaga gcctgagcct ctttttcttg tgcatcctca
      481 atcaagcccc aaatgaagtc ggctgaagca ttgtcaataa caggtgtaat atcagcattg
      541 tcaaatggat caccaactgt taatttagaa acttcttcct gaagcaaagt agctaattta
      601 tctgctacac tttcgagaac aatgacacgt ttaatggccg tgcaacgttg tcctgagtag
      661 ctaaaggctc ccgcaacaat ttgcttggca gcatgttcca aatctgcatc ttctagtaca
      721 agagctgcat ctttcccacc aagttccaac atgataggac gcataccagc taaacgacca
      781 atacgttctc caataggggt tgaacctgta aagttgatga agttgacttc tttgtgctca
      841 atgatataat ccccaatttc tgaaccacga cctgtaatgg tgttgaaaac acctgccgga
      901 atccctgctt cttcaaatgc tttagccaac aagagtccag aaatggaacc ttgtgttggt
      961 ggcttaaaca tgaccacatt ccctgcaatc aaggcaggtg caattttaga agcagataaa
     1021 ttaactggat aattaaaggg agcaatcgct agcacgatac caactggttc acgacggaca
     1081 acagccagtt tgtttttact tgctgcctca aaaccaccac cttccattgc ttgtccagtg
     1141 atacggagac cttcctcagc agcataacga atcaagtctg ctgtacgcac tacttctcca
     1201 attgctgctt taatcccttt tgctacttct ttggcaagga tagtaccaat tttttcctta
     1261 tcgcgttcta aaatagctgc tgttttatgc aaataagccg cacgttcaat tgctgataaa
     1321 gctcgccatg ctggcagggc tgcacgcgca gcttgcatag cctcatcagc ttcagtctga
     1381 gtcatggctg gaactgtacc caattcttct tgattgattg gtgaataaat cgtaatttct
     1441 tgttcagatg atttccattt tccatttact aaattctgat atcttgtcaa attcttgtcc
     1501 tcctgaaaat gattaagata tattttacca aattttcaga aaatcacaac ccttttttca
     1561 aaatttttga gattattttc acaagcttga tttttcaaag tatactcaat aaaaataaaa
     1621 aaaatccact acatcaaggc gagactaatg tggtttgaag aaattttcga agagcgtgaa
     1681 tgagtatcat ctatagtaaa ataaaaaaac tgaacaattt ggttggggac agtcaaacca
     1741 atttctcaca atgttttaga aacaagggtg tgctattcca atttcaggct actataactg
     1801 tcatagattg ctgaaacaaa gtctaggtaa aagtcttcat aataaaaaga ccccctatca
     1861 agtgttcaaa aactttgata ggaggtcttg ttttgtgaaa atatttatca aattttctat
     1921 acaagtgagc tgttagccag gttctttcta ttctttcaat ttcaatgaat ggatttttta
     1981 ccaatactca taactgggaa tttgtctgtg taaaaatagc gagatagatg gtatttataa
     2041 aacactcaag acagctagac taatatcatt taaaacatta tcttcttttg agcgactgtt
     2101 ggttaccaac atagctaaat ttcctgcatt ttcaaattga tagggttctg atttagcatt
     2161 cacaactacc aagaggtgtt ctttgccgtg aacttcatag ataaggcagc cgctatgttc
     2221 aatcgcagaa tgcacaaaga catgatggta aatttcatca tagctagagt aagaaaaggc
     2281 accagttttt gtcttcaatc ggatgacttg acggataaac tcaatactgt cttgacgctc
     2341 attaatcaag ttccagttca cttggttcac actgtcagga gcattatagc tattcatcgc
     2401 acgctctcta tcatcatggg tcaactcacc attttcacca gtcgcaacca gtttggtacg
     2461 accaaattct tgaccgattt ccataaaggc catcccctgc atgagcagat tcatggctgt
     2521 ggcagtttcg accttgcgca tgatttgctc tgaactttgg tctggatgaa gggttgccaa
     2581 taaatcgtga agattgtaat tgtcatgggc ttctacatag ttaagcacct gatttggatg
     2641 tgtataggtt cctaattcac gacttcctag gattgcttta gctagaattg gctctgtcgc
     2701 agcaccactg acaaaacctg acttgatagc accataaact tctccccctt tgacagcatc
     2761 gcgctgattg tcattaaaga aaccaatatt tggcatctgg taggcattgt ccttcttggc
     2821 cttatcataa gggggaagac ctgttcccat atcccatcct tctccataga ggataatgtt
     2881 ggagtcgatt tcatccaagc tttgacgaat catctgcatg gtcttgacat catgaatccc
     2941 catcaagtca aaacggaagc cgtcaatatt atattcctgc acccagtata gaagagaatc
     3001 aatcatatac ttgcgaaaca tttcgtgttc actggctgtt tcatttccaa cacccgttcc
     3061 attctggaag gtaccatctg gattcatacg ataatagtaa tcagggactg ttgtttggaa
     3121 tggtgcatca acaactgaga aggtatggtt atagactaca tccataatga ctccaatacc
     3181 cgcatcgtga taagcttgaa ccatcacctt caaatcacga atgacctgag ctggatcatc
     3241 tggattagtt gaaaaactag tttctggcgc gttatagttt tgtggatcat aaccccagtt
     3301 gtaggttaca tttccatcct catcgtattc tttatgacgg tctgcaattg gttgcaattg
     3361 aacataattg tagcccagct tcttgatgta atcaaaagca gttgactggc cgtattggtt
     3421 aactgttcca gcctgagcag cacccaagaa agttcctcga agatgttcat ctacacccga
     3481 tgtaggtgat ttagtcaaat cacgaatgtg catttcacag ataactgcct tacatggatt
     3541 ttccaagcgc caagtagcct ccgaaccgtg cttaacctcg aagttttcaa cttgcttttc
     3601 tacatggctc agaatagctg aacgtttgcc atcagggctg gtcgcgattg tataaggatc
     3661 acgtgtcagt gtttggtgat gagggaattg gacttgatac tgataagtct tacctaccaa
     3721 atcttcttca acatccaaac tccagacacc gattgtattg tccttatgat tataagagta
     3781 gctattgcct cttttcatct caaaagtctt ccaaacgggt gcatcattag cagctgattc
     3841 ataaacgaca acttgcactt ctgtcgctgt aggtgaccag agggaaaaat gagcctgatt
     3901 gtcctctaca cggcaaccca attctccttg gtaaccccaa tgatgatcaa aactagcact
     3961 gttaatggcc ttatcaaagg caaaaggatt ttgattttta tagaaaggac tggcaatagc
     4021 aggattttca gagtaataaa tcctatcatc gccttccaaa atccagacct ctgttaatag
     4081 gggatagtga ttaaaacgga tagaatattc tttactagtt tgacctgtat gaaccacaaa
     4141 attcaagctt tctataacat gtgaacttgg gtgttcaaag ctaaataaag ctccaaaata
     4201 atcttctttg taggttagca aatcaattcg ttgatcctga ctttttacaa aggagcaagt
     4261 gtcatattct ccattcttac gatggtaatg aatgcgcata gggtagttat acatttttta
     4321 tttttccttt ttactttgtt tctatttcac taataaattt ttgtcaatct cgtctcaatt
     4381 aacagacata gtcatattct ctaaactctg tttttaaacg atccattaca aactttctag
     4441 ccatgcctca tctctgacct ggataccaag ttcttgtgct ttttgcagct tacttccagc
     4501 gtctgcacct accacgacga ggttggtctt tttagaaaca ctacctgtca ctttggcacc
     4561 cagactttcg agtttacttt tagcttctga gcgcttgagt cgttccaatt ttcctgtcaa
     4621 taccacggtc aaacctgaca aggccgcatc cgctactacc gtctgtcctt tatagtccag
     4681 attgacccca gtttctttca attctctgag cagaatttca gagccttctg tcgcaaaata
     4741 agtctgaaga cttttggcaa tcacgccacc tagactttca atactagcca cttcctctga
     4801 atctgcctga tacagatttt caattgaatg gaaatattga agtaaaagct gactagcctt
     4861 gcttccgaca tgacgaattc ccaaaccaaa taagagcttc tcggcagaat tttcctttga
     4921 tgcttggata gcctgataca gtttagcagc ggacttttcc ttaaccccct ctaaaaggag
     4981 gaaatcctct tcttgcaaac gataaatatc cgccacatcc ttgactaaat tagcagcaaa
     5041 aagcttctca acaatagatg gaccaaggcc tgtaatattc atagcatcac gagaagcaaa
     5101 gtgaatcaag ccttccatga tttgagcagg gcaacgcgga ttgatacaac gtagggccac
     5161 ttcatcttca aagtgcaaca agtcagagtt acaacttgga cagtttgtag ggatatctag
     5221 tttttcttca gaaacccgtt tggactctac cacacgtaaa acggcaggga tgatgtcacc
     5281 agccttatat acaatgaccg tatcgtcttt tcggatatct ttttcagcaa tataatctac
     5341 attgtgcagg gtcgcacggc taacagtcgt accggcaagt tgtactggtg ttagattagc
     5401 agttggagtt acaacaccgg tacggccaac tgtccagtca actgataaga gttgagcttc
     5461 tttttcttca gcagggaact tgtaggctac tgcccacttt ggagccttaa ctgtaaaacc
     5521 aagttcttct tgacttgcta ggtcgttgac cttgattacc actccatcaa tatcgtaagg
     5581 cagattttcc cgttcctgtc ctacttcttg gataaaattc cagatttcat ctatgttttc
     5641 agccaagatt cgcttaggat tgaccacaaa acctagttgt tctaggtact tcaaaccctt
     5701 ttcttggcta tcacgagttg aagggctggc ttcttgatag agaaacgttg caagattacg
     5761 cttggcaact actgctgtat ccaactgacg cagagttcct gctgccgcat tacgaggatt
     5821 agcaaattca ggctctccat tttcttggcg cacttggtta acttggtcaa aggaagcgcg
     5881 tggcatgtaa cattccccac gaactgtgat atctagttct tctggcaaag tcaaagggat
     5941 gtccttaaca cgcttgaggt tttctgtgat attttcacca attgaaccat ctccacgtgt
     6001 taccccagca accaaaatcc ccttttcata agtcagcgag atagataagc catcgatttt
     6061 cagctcacaa atataggtcg gatgagccac ttccttacga acacgcgcat caaaagcatc
     6121 tagctcctca cgtgaaaaag catcctgcaa actataaaga ggatactgat gactgtattt
     6181 ttcaaaacca tctaaaacct tgccaccaac acgatgagtc ggactgtctg ctagcacttg
     6241 ctctggataa gcagtttcta actcgaccaa ctcacggtaa aggcggtcat actcactgtc
     6301 tgcaaccgag ggattatcgc tggtatagta ctcagtcgca tagcgattga gcaaagcgac
     6361 taactcattc attcttttat tcataagacc attttaccat aaaacaagcc ctcctcacaa
     6421 acgagaaggg cggaaaaaac acttagtttg aaattatttt tgaaactcaa gcaaccttat
     6481 atcaattttt caaaatgagt tcgaacataa ataaacgata tacaagacaa gatgataaca
     6541 ccacttccaa ttatcaggaa agaagagaga tgtacacttg gcaagactgt cataaatcct
     6601 tttgcaatag gcataaatag aatagctaag gtaaaaattg tactcagtac tcttccaaga
     6661 aattcgctct caaccttggt ttgtacttga gtaaaaaagt gaatattaaa aatcgtcata
     6721 aacaattcac aaactaaatt tccagaaaag gaaagaaaag ttggaagtgg taatcccatc
     6781 ataaaaactc cgacacctgt caaagccagt aaaatcaaaa gattataaat attagctttt
     6841 gattttactg gctagaagag ccccaatgat ggaaccaata gcccccatag ttaaaatact
     6901 tgcataggct ccttctgacc cgtaaagctg attcgaaaag ggaagtagaa attcaaaagc
     6961 tgcaaaaaag aaattaacgc tggaagctac cagcaaaagg aagaaaattt cttgctgatg
     7021 ccagatatag tgtaacccat ccttgatatc tacaaaaata tctctcccag taaaagcctt
     7081 tttctcttga acttttgctt cctcttttgg aaggaaagcc actagaacaa aagcaatgaa
     7141 aaaagtcagc gagtctagca gtagcgtcat atggagactt gcaaactgta aaacaaggaa
     7201 ggaaagaaca ggagagctaa cacctacaac ctgcaaaacc agctctaagc gagaattata
     7261 gatcacaatc tcatctttct ccaccacttc agttatgata gctttattgg ctgtgcgaga
     7321 aaaggcaaaa gcaatagcct gcacaatgtt agcaacaatc aaagcgccaa tcatccagct
     7381 atcattcctt atgaaagaaa tagccagaca aagaatccca caaacaagat ctgccgtcat
     7441 taaaatctta cgacgagaaa aacggtctga aataactccg ccaaagggat tgacgagaat
     7501 agatgtgacg agctcagaaa tctgatacat tcctaaaact gtctgtccta tagtccccat
     7561 agaagccaac cagacactat ttccataatc atagagcata tttcccattt tattgatagc
     7621 cccacggcta atcaactgca ctgcatagcg attcatatta aagctcctct caaattttga
     7681 aactattgta tcaaaaccga aaggagcttt ttattttttc ccttatttgg gaaaattaac
     7741 ttttgacaaa tttttcgtag tgttcctgat aataggctac ttgctctgga agacctaaca
     7801 catcaaaaat atgcatggcc tcttgcatct gcttacagcc ttctttacac tgtccttttt
     7861 gatataaggc aaaacctttt aaataatgga aaacattacg ctcataaagc ttaatacctt
     7921 tgtcaataat cttctctgta taagcctcaa aatagttggc attataaaaa gaagaatgct
     7981 ctaaacaatg ctggtaacaa ttgagggcca aaatcaacac taatctctta tggcgactaa
     8041 tctcttggta aaattcctcc ctctccataa cttctctacc aatccgagtg acatagtcta
     8101 catcgtagaa actatagagg ttaccgaaaa gaatcaactc atacatggtc cattcttctg
     8161 ttttgaagag ataatctgct accttatcca aatcatcctg cttcatatca taactcgcat
     8221 ctctttgaca aatcagacct tgtagcaaaa tccagttcag ctcaaaataa aggggagtcg
     8281 tcgaactctt agacttttca agttgttctc tttgaagctt ttgaaaacct gcaatatcgt
     8341 ttgaatagta aagtgggata atctgtgcca tcatagacac atgttcatga ttatgaaaat
     8401 tccttgcctt atccatgaaa ttttcgattg ttacatgaat gttatccaaa atctcaaaga
     8461 aacgggagac tgccaggtca gactccccaa gctcaaagcg agataactga gaggtagagc
     8521 aggattcgcc tgctgcttcc tttaaagaat aatttccact tgttcgaaat tcacgaaata
     8581 cttttccaag atgttccatc tttacacctg ctctgataat tcttcccact caagcatagc
     8641 ttcttcctga cgatggctga ttttgtccag ctcagcctgt aattccatga gtttgtcggc
     8701 atcgtttgtt tccaacattt gttcagaaat ggcttggctt tgactttcta gctcttcaat
     8761 ttcagcttct agactttcga tttgtcgcat gagtttgcga acttcttttt gactttcttt
     8821 ctgggcctga tagtcattga ctggacttgc ttcctttgct tgattgctag ttgaagcttc
     8881 ctcagtctga ctcatttctg ctgttgcttt cttctcaaca tagtagtcgt aatctccaag
     8941 gtagagagtt gaaccattct cagacaattc caaaacatga gttgccacac gattgataaa
     9001 gtaacgatca tgactgacaa acagcaaggt tccatcaaag tcaatcaagg cattttctag
     9061 cacttcctta ctatcaatat ccaagtggtt ggtcggctca tccagaatca aaaagttatt
     9121 gttttccata gacaatttag ctaaaagcaa acgagctttt tcgccaccag atagcatgcc
     9181 gactgatttt ttaacatcat ctcctgagaa aaggaaggct ccaagacggt tgcggatttc
     9241 aacttctggt gtcagtttga aatcattcca gagttcatcc agcaccgtat tacttggtgt
     9301 cagcttgctt tgggtttggt catagtaacc aacctcaaca ttagcgccaa agcgcttttc
     9361 tcccttgata aaaggaatct ggtccacaat agacttgata aaggttgact tgccgatacc
     9421 atttggacca acgatagcga cagcattcat cttacgaaga tctaggttga taggttgtga
     9481 caagacttcc ccgtcatagc caacagctgc attttcaaca gtcaaaacaa cattgcccga
     9541 cgttttttca gactggaagg tcatgttggc tgatttcttg ccagcttcag gcttgtccaa
     9601 acgttccatt ttttccagtt gtttacggcg agattgagca cgtttagtcg ttgaagcacg
     9661 aactagattg cgattgacaa agtcttccag agcagagatt tccttctgtt gcttttcata
     9721 gttttttgcc tcagtaacta gcttttgctc cttcaattcg acaaaacgag agtaattccc
     9781 cacatagcga tccaaggaat gcttggtcaa atctagcgta attgtcgcaa ccttgtccaa
     9841 gaaataacgg tcgtggctga cgataatgag ggcaccgcta tagtttacca agtaattctc
     9901 tagccaggag atggtttcaa tatccaagtg gttagttggc tcgtccaaga ccaagagatt
     9961 gggcttttca aggagcattt tagctagagc caaacgagta ttttgaccac cagaaagctc
    10021 agcaattttc atctgccaca tagactcgtc aaacttgaat ccattcaaaa tcgctcgaat
    10081 atcagcttca taggtaaagc cacctgcttg gcgaaaattc tcagataagc ggtcataatc
    10141 tgacatcagt ttatccaaat cctcaccaga cttttcaccc atctccagct ccatctgacg
    10201 cagttgtctc tccgtccgac gcaaattatt aaagacatga agcatttcat cgtagatggt
    10261 attttcagac tcaaaacggc tatcttgggc taggtaagac agagaaatat cttttttctt
    10321 attgatttct ccgctagttg gctcctcttc tccaactaaa atcttcaaaa gagtagactt
    10381 acctgcacca tttttcccaa caagggcaat ccgatctcgt tcatcaacct gcaggttgat
    10441 attatcgaaa agaacctctc ctgcaaaaga acgttcaatt ttattagctt gtaaaataat
    10501 cataagagta gtatagcatg tttccctaag gcattcaaga taatcgtaag tcttttagta
    10561 caacttttat aacataaaat aaactaaatt atgtatattt tatattagat tcttcactat
    10621 cttgttggat tttctaacca gctaatcttg tttcaaatag ttatcgcaca agcctattat
    10681 ttaattcttt tcatt
//
LOCUS       DAVLXH010000061        10675 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00028199
            SAMN33607166-rid17955573.denovo.061, whole genome shotgun sequence.
ACCESSION   DAVLXH010000061 DAVLXH010000000
VERSION     DAVLXH010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607166
            Sequence Read Archive: SRR23725544
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10675)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10675)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721421.1
            Genome Coverage       :: 115x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:42:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,210
            CDSs (total)                      :: 2,161
            Genes (coding)                    :: 2,023
            CDSs (with protein)               :: 2,023
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 73 of 138
            Pseudo Genes (incomplete)         :: 60 of 138
            Pseudo Genes (internal stop)      :: 40 of 138
            Pseudo Genes (multiple problems)  :: 31 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10675
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607166-rid17955573.denovo.061"
                     /strain="AUSMDU00028199"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1349"
     gene            1..610
                     /locus_tag="VYO11_001824"
                     /pseudo
     CDS             1..610
                     /locus_tag="VYO11_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            510..956
                     /locus_tag="VYO11_001825"
     CDS             510..956
                     /locus_tag="VYO11_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEV1596335.1"
                     /translation="MRKHGLISKSTSKGYYQVAIPFTRLFCLVLVSIDYINCLSETTD
                     KNWHKSDRIFVTNTGKPVHSSILSKSLQRANERLKKPIPKHLSPHIFRHTTISILSEN
                     KIPLKTITDRVDHSDSEVTTSIYTHVTKNMKDEAINVLDKVMKKIF"
     gene            complement(1094..2398)
                     /gene="eno"
                     /locus_tag="VYO11_001826"
     CDS             complement(1094..2398)
                     /gene="eno"
                     /locus_tag="VYO11_001826"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HEV1596336.1"
                     /translation="MSIITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTG
                     EHEAVELRDGDKSRYGGLGTQKAVDNVNNIIAEAIIGYDVRDQQAIDRAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEIPLYSYLGGFNTKVLPTPMMNIINGGSHSDAPI
                     AFQEFMILPVGAPTFKEALRYGAEIFHALKKILKSRGLETAVGDEGGFAPRFEGTEDG
                     VETILAAIEAAGYVPGKDVFIGFDCASSEFYDKERKVYDYTKFEGEGAAVRTSAEQID
                     YLEELVNKYPIITIEDGMDENDWDGWKALTERLGKKVQLVGDDFFVTNTDYLARGIQE
                     GAANSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAGQ
                     IKTGSLSRTDRIAKYNQLLRIEDQLGEVAEYRGLKSFYNLKK"
     gene            2562..3008
                     /locus_tag="VYO11_001827"
     CDS             2562..3008
                     /locus_tag="VYO11_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000131081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HEV1596337.1"
                     /translation="MTDLSKQLLEKAHGGLKINPDEQRRYLGTFEERVLGYVDIDTAN
                     SPQLEKGFLFILENLQEKAEPLFVKISPTIEFDKQVFYLKEAKETDSQATIVSEEHIT
                     SPFGLVIHSNAPVQVEEKDLRLAFPKLWEVKKEEPAKTSLWKKWFS"
     gene            complement(3005..4120)
                     /locus_tag="VYO11_001828"
     CDS             complement(3005..4120)
                     /locus_tag="VYO11_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HEV1596338.1"
                     /translation="MKIVIAPDSFKESLTAQQVAEAIKRGFQQSIADVECLLCPVGDG
                     GEGTVDAIRHSLDLKEKWIQVTDPFGQKEAMRYFQKGELALFEVADLVGLGKIPLEKR
                     NPLQIQTCGIGELILHLISKGIKDIYIGVGGTASNDGGLGIAAGLGYQFYDRDGNVLP
                     ASGQSLLNLASVSTENRYKIPEGVQIHILADVVSPLCGHQGATYTFGNQKGLHPTMFA
                     VVDQAIQDFYEKFSPATLEIKGAGAGGGLAGGLCAFAQASIVSGIDTCLDLINFDKKV
                     SDADLVVVGEGRLDSQSFAGKAPIGVAKRTPVGVPVIAICGSLAEDLPPLPFENIQAV
                     FSILEKSEPLEDSLKNASLYLERTAANIGHLLNMCKI"
     gene            complement(4129..4774)
                     /gene="serB"
                     /locus_tag="VYO11_001829"
                     /pseudo
     CDS             complement(4129..4774)
                     /gene="serB"
                     /locus_tag="VYO11_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000084485.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoserine phosphatase SerB"
     gene            complement(4833..6266)
                     /gene="glgA"
                     /locus_tag="VYO11_001830"
     CDS             complement(4833..6266)
                     /gene="glgA"
                     /locus_tag="VYO11_001830"
                     /EC_number="2.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen synthase GlgA"
                     /protein_id="HEV1596339.1"
                     /translation="MKILFVAAEGAPFSKTGGLGDVIGALPKSLVKAGHEVAVILPYY
                     DMVEAKFGNQIEDVLHFEVSVGWRRQYCGIKKTVLNGVTFYFIDNQYYFFRGHVYGDF
                     DDGERFAFFQLAAIEAMERIDFIPDLLHVHDYHTAMIPFLLKEKYRWIQAYEDIETVL
                     TIHNLEFQGQFSEGMLGDLFGVGFERYADGTLRWNNCLNWMKAGILYANRVSTVSPSY
                     AHEIMTSQFGCNLDQILKMESGKVSGIVNGIDADLYNPQTDALLDYHFNQEDLSGKAK
                     NKAKLQERVGLPVRADVPLVGIVSRLTRQKGFDVVVESLHHILQEDVQIVLLGTGDPA
                     FEGAFSWFAQIYPDKLSTNITFDVKLAQEIYAACDLFLMPSRFEPCGLSQMMAMRYGT
                     LPLVHEVGGLRDTVRAFNPIEGSGTGFSFDNLSPYWLNWTFQTALDLYRNHPDIWRNL
                     QKQAMESDFSWDTACKSYLDLYHSLVN"
     gene            complement(6263..7402)
                     /gene="glgD"
                     /locus_tag="VYO11_001831"
     CDS             complement(6263..7402)
                     /gene="glgD"
                     /locus_tag="VYO11_001831"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase subunit
                     GlgD"
                     /protein_id="HEV1596340.1"
                     /translation="MKIDKYSAILGNTVGFHNMSTLTDHRPVASLPFGGKYRLIDFPL
                     SSLANAGVRSVFGIFQQDNISSVFDHIRSGREWGLSTLLSHYYLGIYNTRVESSTVGK
                     EYYQQLLTYLKRSGSNQTVALNCDVLINIDLNQVFHLHSTTKEPITVVYKKLAKKDIS
                     EVNAILDVDETDHVLSHKLFDSKSTAETFNMSTDIFVVDTPWLIEHLEEEAKKEHPEK
                     LRYVLRDLAVKEGAFAYEYTGYLANIHSVKSYYQANIDMLESQKFYSLFSPNQKIYTK
                     VKNEEPTYYANTSKVSTSQFASGSIIEGQVANSVLSRNIHVHKDSLVKDSLLFPRVVI
                     GEGAQVEYAILDKGVEVEPGVVIRGTAEHPVVVKKGAKVTEDIHS"
     gene            complement(7392..8534)
                     /locus_tag="VYO11_001832"
     CDS             complement(7392..8534)
                     /locus_tag="VYO11_001832"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000787267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase"
                     /protein_id="HEV1596341.1"
                     /translation="MKNEMLALILAGGQGTRLGKLTQSIAKPAVQFGGRYRIIDFALS
                     NCANSGIHNVGVVTQYQPLALNNHIGNGSSWGLDGINSGVSILQPYSASEGNRWFEGT
                     SHAIYQNIDYIDSVNPEYVLILSGDHIYKMDYDDMLQSHKDNNASLTVAVLDVPLKEA
                     SRFGIMNTDANNRIVEFEEKPTQPKSTKASMGIYIFDWQRLRNMLVAAEKSKVGMSDF
                     GKNVIPNYLESGESVYAYEFSGYWKDVGTIESLWEANMEYISPENALDSRNRQWKIYS
                     RNLISPPNFLGANAHVEDSLVVDGCFVDGTVKHSILSTGAQVREGAEVLDSVIMSGAI
                     IGQGAKIKRAIIGEGAIISDGVEIDGTDEVQVVGYNEVVGVATDED"
     gene            complement(8524..10452)
                     /gene="glgB"
                     /locus_tag="VYO11_001833"
     CDS             complement(8524..10452)
                     /gene="glgB"
                     /locus_tag="VYO11_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-alpha-glucan branching protein GlgB"
                     /protein_id="HEV1596342.1"
                     /translation="MDNREALKTFMTGENFYLQHYLGAHREELNGEHGYTFRVWAPNA
                     QAVHLVGDFTNWIENQIPMVRNDFGVWEVFTNMAQEGHIYKYHVTRQNGHQLMKIDPF
                     AVRYEARPGTGAIVTELPDKKWRDGLWLARRKRWGFAERPVNIYEVHAGSWKRNPDGS
                     PYSFAQLKDELIPYLVEMNYTHIEFMPLMSHPLGLSWGYQLMGYFALEHAYGRPEEFQ
                     DFVEECHTHNIGVIVDWVPGHFTINDDALAYYDGTPTFEYQDHNKAHNHGWGALNFDL
                     GKNEVQSFLISCIKHWIDVYHLDGIRVDAVSNMLYLDYDDAPWTPNKDGGNLNYEGYY
                     FLQRLNEVIKLEYPDVMMIAEESSSATKITGMKEIGGLGFDYKWNMGWMNDILRFYEE
                     DPIYRKYDFNLVTFSFMYVFKENYLLPFSHDEVVHGKKSMMHKMWGDRYNQFAGLRNL
                     YTYQICHPGKKLLFMGSEYGQFLEWKSEEQLEWSNIEDPMNAKMKYFTSQLNQFYKDH
                     RCLWEIDTSYDGIEIIDADNRDQSVLSFIRKGKKGEMLVCIFNMVPVERKDFTIGLPV
                     AGIYEEVWNTELEEWGGVWKEHNQTVQTQEGLWKDYEQTLTFTLPAMGASVWKIKRRL
                     KSTKTVTNKNQKGVENEK"
BASE COUNT         3269 a         2348 c         1884 g         3174 t
ORIGIN      
        1 aagctaaaag agaaaacagg agagctaaac caccaagtaa aaggaacaaa accaagaaaa
       61 gttgatagag atagacttaa aaactatctt actgacaatc cagatgctta tttgactgaa
      121 atagcttctg aatttggctg tcatccaact accatccact atgcgctcaa agctatgggc
      181 tacactcgaa aaaaagaacc acacctacta tgaacaagac ccagaaaaag tagccttatt
      241 tcttaagaat tttaatagtt taaagcacct agcacaggtc taacaaataa atggtgagtt
      301 aatcgctcca atgatttacg aagagacgat gacgagcgac ttttttgaag cttggtttca
      361 gaagtttctc ttaccaacat taaccacacc atcggttatt attatggata atgcaagatt
      421 ccatagaatg gggaagctag aacttttatg cgaagagttt gggcataaac ttttacctct
      481 tcctccctac tcgcctgagt acaatcttat tgagaaaaca tgggctcata tcaaaaagca
      541 cctcaaaagg gtattaccaa gttgcaatac cttttacgag gctcttttgt cttgttcttg
      601 tttcaattga ctatataaat tgtctaagcg aaacaaccga taagaattgg cacaaaagcg
      661 accgtatttt tgttaccaat acaggaaaac cagttcatag ttctatcttg agcaagtctc
      721 tccagcgagc aaacgaacgc cttaaaaaac caattcccaa acatctgtcc cctcacatct
      781 tcagacacac cactattagc atcttatcag aaaataaaat tcctttaaaa acaatcacgg
      841 acagggttga tcattccgac tctgaagtca ctacttccat ctacacccac gtcacaaaga
      901 acatgaaaga tgaagcaatc aatgtactgg ataaagttat gaaaaagatt ttttaaaaag
      961 ttttgtccct tttttgccct ctaaatacaa aaatagccct tcggataaaa tccgaggggc
     1021 tagaaacgtt gttaaatcaa cggccgaact tttgaatttc atggttcggg ataaaatagt
     1081 tcactgaact attttatttt ttaaggttgt agaatgattt caatccacga tattcagcta
     1141 cttcaccaag ttggtcttcg atacgaagca attggttgta tttagcgata cggtctgtac
     1201 gtgaaagtga accagtcttg atttgtcctg cgttagttgc aactgcgata tcagcgattg
     1261 ttgaatcttc agtttcacct gaacggtgtg atacaacagc agtgtaacca gcttctttag
     1321 ccatttcgat agcttcaaaa gtttcagtaa gagtaccgat ttggttaact ttgataagga
     1381 ttgagttagc agcaccttct tggataccac gtgcaaggta gtcagtgttt gttacgaaga
     1441 agtcgtcacc aacaagttgt actttcttac caagacgttc agtaagagct ttccaaccat
     1501 cccagtcgtt ttcatccata ccatcttcaa tagtgatgat tgggtatttg ttaaccaatt
     1561 cttcaaggta gtcgatttgt tctgcagatg tacgaacagc agcaccttca ccttcaaatt
     1621 tagtgtagtc gtaaacttta cgttctttat cgtagaattc tgatgaagca cagtcaaatc
     1681 cgataaatac gtctttacct ggtacatatc cagcagcttc aatcgcagca aggatagttt
     1741 caacaccatc ttcagttcct tcgaaacgag gagcgaatcc accttcgtca cctacggcag
     1801 tttccaaacc acgtgattta aggattttct taagagcgtg gaagatttca gcaccgtaac
     1861 gaagggcttc tttaaatgtt ggcgcaccaa ctggcaagat catgaactct tggaaagcaa
     1921 ttggagcgtc agagtgagaa ccaccgttga tgatgttcat cattggagtt ggaagaactt
     1981 tagtgttgaa tccaccaaga tagctgtaaa gtgggatttc aaggtagtca gcagcagcac
     2041 gagctacagc gatagacaca ccgaggattg cattcgcacc caatttacct ttgttaggag
     2101 taccgtcaag tgcgatcata gcacggtcaa tagcttgttg atcacgtaca tcgtagccaa
     2161 tgatagcttc agcaatgatg ttgtttacgt tgtcaacagc tttttgtgta ccaagaccac
     2221 cgtaacgaga tttgtcaccg tcgcgaagtt caactgcttc gtgttcacca gtagaagctc
     2281 ctgatggaac cataccacgt ccgaaagcac ctgattcagt gtaaacttct acttcaagtg
     2341 ttgggttacc gcgtgagtct aggacttcgc gagcgtaaac atcagtaata attgacattt
     2401 tttactctcc ttatgagtta aattttttac acctctataa taccttaaaa cccctccttt
     2461 ttcaagaaaa aacgttatct ttgtgcaact tttccttaac tttataaagt aatcgctttc
     2521 ttttgtctgt tttattctaa cttttatgat atactgtttt catgacagat ttatcaaaac
     2581 aattacttga aaaagctcat ggtgggttaa aaataaatcc ggatgagcaa agacgctatc
     2641 ttggtacttt tgaggaaaga gttcttggat atgtagatat tgacacagca aatagccctc
     2701 agttagaaaa aggcttttta tttattttag aaaaccttca ggaaaaagca gagccactat
     2761 ttgtgaagat ttcaccaact atcgaatttg ataagcaagt tttctactta aaagaagcaa
     2821 aagaaactga tagtcaagcc accatagtat ctgaagagca tattacttct ccttttggcc
     2881 tggttattca tagcaatgca ccagttcaag tagaagaaaa agaccttcga cttgcttttc
     2941 caaaactttg ggaagttaaa aaggaagaac cagccaaaac atccttatgg aagaaatggt
     3001 ttagctaaat cttgcacata tttaataagt gcccaatatt ggcagccgtg cgctccagat
     3061 agagactggc atttttcaaa ctatcttcta aaggttcact tttctccaaa atagaaaaga
     3121 cagcttggat attttcaaat ggtaggggag gtaaatcttc agcaagacta ccgcaaatag
     3181 caataacagg aactccaaca ggggttcttt ttgcaacacc tataggcgct ttcccagcaa
     3241 agctttgact atcaagtctt ccttctccaa caacaaccaa gtcagcatct gaaactttct
     3301 tatcaaagtt gattaagtcc aagcaggtat caattccaga cacgatactt gcctgagcaa
     3361 aggcacacaa accaccagca aggcctccac ctgctcctgc tcctttaatt tctaatgttg
     3421 caggtgagaa tttttcataa aaatcttgga tcgcctgatc tactactgca aacatagtcg
     3481 gatgtagacc tttttgattg ccaaaagtgt aagtcgcacc ttgatgacca cataagggac
     3541 tcacgacatc tgctaaaata tgaatttgaa caccttcagg aattttatag cgattttctg
     3601 ttgaaacaga agctaagttt aataaggatt gaccggaagc aggcaagaca tttccatccc
     3661 tatcataaaa ttgataacct aaaccagcag caatccccag tcctccatca ttactggccg
     3721 tgccaccaac accgatataa atatctttaa tccctttaga aatgagatgg agaatcaact
     3781 ctccaatacc acaagtttgg atttgaagtg gatttcgttt ctctagcgga atttttccaa
     3841 gaccaaccaa gtcagctact tcaaatagtg ccagttcccc tttttgaaaa tagcgcatgg
     3901 cttctttttg tccaaaaggg tctgtcactt ggatccattt ttcttttagg tcaagagaat
     3961 gtcggatagc atctacagta ccttctcccc catcaccaac agggcagagg agacattcta
     4021 catctgctat cgattgttgg aagcctcttt ttattgcttc agctacctgt tgagctgtca
     4081 agctttcctt aaacgaatcc ggtgcaatta caatcttcat attttccctc attctaaaca
     4141 gtcaatcaaa ggaagaactt ctaaaaaatc cctcttgtca acatgatgtg gtatttcttt
     4201 tttgagcatt tctttggaac aaaaggcgat tcctaactcc gccgacttca acattaatag
     4261 attattgacc ccatcaccga ttgccaccgt tctttcttta gaaagtttta gtttctttct
     4321 ccatttttcc agagtttctt ttttgacctg gggacttata atttgtccaa ctaattttcc
     4381 tgttaaaaga ccttctttga cttcaagctg gttggcagtg aaataggcaa taccaaggga
     4441 ttttgctaat ctctccaact attggtgtaa atccaccagg caccagacca actaggatgc
     4501 cattcttttg gagaatagag atgaactctg ggacatttag cgatagatga attgagttga
     4561 agacgttatc aaagaccaaa ataggaagac cttccaacaa ggacactctt tttcttaaac
     4621 tgctttcaaa gaccaactct cctcgcattg ctcgacttgt aatctgcgaa atttccgcct
     4681 catgacctgc ctctctccct aaaagatcaa tcacttcttc taggattaag gttccatcta
     4741 catccaaaac acacaagcct tttacttgag acatcagttc tcctctctaa acagcctaaa
     4801 aatcgtatga agtcatcata cgattttatc tattaattaa ctaaactatg gtacaagtca
     4861 aggtatgact tgcaggctgt atcccatgag aagtcactct ccatagcttg tttttgtagg
     4921 tttctccaaa tgtctggatg gtttctatac aagtccaatg ctgtttggaa agtccaattt
     4981 aaccaataag gagatagatt gtcaaagcta aagccagtac cgcttccttc gattggattg
     5041 aaagcgcgaa ctgtatctcg caagcctcca acttcatgga ccaatggcaa ggttccataa
     5101 cgcatagcca tcatttgaga caagccacac ggttcaaaac gacttggcat gaggaagagg
     5161 tcacaagcag cgtagatttc ctgagcaagt ttgacatcaa aagtgatatt tgttgatagc
     5221 ttgtctgggt aaatctgagc aaaccatgag aaagctcctt caaaggctgg atcgccagtt
     5281 cccaaaagaa caatctgaac atcttcttgc aagatatggt gaagactttc gaccaccaca
     5341 tcaaaacctt tttgacgtgt caaacgagaa acaattccca ccagtggaac gtctgctcta
     5401 acaggcaagc caactctttc ttgcaatttt gccttatttt tggctttccc agacaaatct
     5461 tcctgattga aatgatagtc taaaagagca tccgtctgag gattataaag atcagcatca
     5521 atcccattca cgataccaga tactttacca gactccattt taagaatctg atccaaatta
     5581 catccaaact gactagtcat aatttcatga gcatagctag gtgaaacagt tgaaacacgg
     5641 ttcgcataga gaatacctgc cttcatccag ttcagacagt tgttccatcg aagggtgcca
     5701 tcagcgtaac gttcaaagcc aactccaaac aaatcaccca acattccttc tgaaaattgt
     5761 ccttggaatt ctaaattatg aatggttaaa actgtttcaa tgtcctcata ggcttgaatc
     5821 caacggtatt tttccttcaa caagaaagga atcatagctg tatggtagtc atgaacatgg
     5881 agaagatcag gaataaagtc aatcctttcc atagcctcaa tggcagccag ttggaaaaag
     5941 gcaaagcgtt ctccgtcatc aaaatcaccg taaacatgac cacggaagaa ataatattga
     6001 ttgtcaataa agtagaaggt tacaccattt aatactgttt tcttaattcc acaatactgt
     6061 ctgcgccaac caacgctcac ctcaaaatga agcacatctt caatctgatt tccaaattta
     6121 gcctctacca tatcatagta gggtaaaatc actgcaactt cgtgcccagc ttttaccagt
     6181 gattttggaa gagcgccaat gacgtctccc aaaccacctg tttttgaaaa gggtgcaccc
     6241 tctgctgcta caaataaaat tttcatgaat gaatatcctc tgttacttta gcacctttct
     6301 taaccacaac tggatgttct gcagttcctc gaatcacaac accaggctca acttcaaccc
     6361 ctttgtccaa gatagcatat tcgacctgag ctccttctcc aataacaaca cgagggaaga
     6421 gcaggctatc tttaaccaag ctatccttat ggacatgaat attacgtgat aaaacagaat
     6481 tagctacttg accttcaata atactaccag aggcaaactg agaagtgctt accttagatg
     6541 tattagcata gtaagttggc tcttcgtttt tgacctttgt ataaatcttt tggtttggtg
     6601 agaaaagaga atagaatttt tgtgattcaa gcatatcgat attcgcttga taataagatt
     6661 taacagagtg aatattggct agatagcctg tgtactcgta ggcgaaagct ccctctttta
     6721 cagccaaatc ccgtaaaaca tagcgcaatt tctctggatg ttctttttta gcttcttctt
     6781 ccaagtgttc aatcaaccaa ggtgtatcaa cgacaaagat atctgtagac atattgaacg
     6841 tttcagctgt tgacttgcta tcaaagagtt tatgagaaag aacatggtct gtttcatcta
     6901 catccaagat tgcatttact tctgaaatat ctttcttagc tagtttttta taaactacag
     6961 tgataggctc ttttgttgta ctatgtaggt gaaaaacttg gttcaaatca atgttaataa
     7021 gaacatcgca gttgagggca accgtttggt ttgagccaga acgtttcaaa taagtaagaa
     7081 gctgttggta gtattctttt ccaactgtac tactttctac acgggtattg taaattccta
     7141 gatagtaatg actaagaagg gttgataagc cccactcgcg tcctgaacga atatggtcaa
     7201 atactgagct gatattatcc tgctggaaaa taccaaagac actacgaaca cctgcattag
     7261 caaggcttga aagtgggaag tcaatcaaac gatatttccc accaaatggc aaacttgcta
     7321 ctggacggtg gtccgtcaat gtcgacatat tgtgaaaacc aactgtattt cctaaaatgg
     7381 cagaatattt atcaatcttc atctgttgct acccccacta cttcattata tcctacaact
     7441 tgtacttcat ctgttccatc aatttcgaca ccgtcagaaa taatcgcacc ttcaccaata
     7501 atggcacgtt taatcttagc tccttgacca atgatagctc cactcatgat aactgaatca
     7561 aggacttccg ctccttcgcg aacttgcgcg cctgttgaaa ggatagaatg tttaacagtt
     7621 ccatcaacga aacatccgtc tacaactaat gagtcttcca catgagcatt tgccccgagg
     7681 aagtttggtg gtgaaatcaa gtttcttgag taaatcttcc attgacggtt acgactatcc
     7741 aaggcatttt ctggagaaat atactccatg ttcgcttccc aaagtgactc aatagtacca
     7801 acatctttcc aataaccact aaattcgtaa gcataaacac tttcacctga ctcaaggtaa
     7861 tttggaatga catttttacc aaagtctgac atgccaacct tgctcttttc agcagcgact
     7921 aacatattac gaaggcgttg ccaatcaaaa atgtagattc ccatagaagc ttttgtagat
     7981 ttaggttgag ttggtttttc ttcaaattca acaatacgat tgttagcatc tgtgttcatg
     8041 ataccaaaac ggcttgcttc tttaagaggg acgtctaaaa ctgctactgt caagctggca
     8101 ttattatcct tatgagactg gagcatatca tcatagtcca ttttgtagat gtggtcccca
     8161 gacaaaatca agacatactc aggattgaca ctgtcgatat agtcgatatt ttggtaaata
     8221 gcgtgactag ttccctcaaa ccaacgattt ccttcacttg cagaataagg ttgaagaata
     8281 gagacgcctg aattaatacc gtctagtccc cagcttgaac cattcccaat atggttgttg
     8341 agagcaagtg gttgatactg tgtaacgacc ccaacattat gaatccctga gttggcacag
     8401 tttgataggg caaagtcaat gatacggtag cgcccaccaa attgcacagc tggttttgcg
     8461 atgctttgag tgagtttacc gagacgagtt ccttgcccac cagcaagaat caaagctaac
     8521 atttcatttt tcattttcta ctcctttttg gtttttattt gtgacggttt tagtagattt
     8581 caagcgacgt ttgattttcc atacacttgc tcccatagcc ggtagagtaa aggttaaggt
     8641 ctgctcataa tctttccata gtccttcttg cgtttgaaca gtttgattat gttctttcca
     8701 aacgcctccc cactcttcca actcagtatt ccatacttct tcgtaaattc ctgcaacggg
     8761 tagtccgatt gtaaaatctt tccgctcaac aggtaccatg ttaaagatac agactaacat
     8821 ttctcccttt ttacccttac gaataaagga aagaacactc tggtctcgat tatccgcatc
     8881 aatgatttca ataccatcat agctggtatc gatttcccac agacagcgat gatctttgta
     8941 aaactggttt agctgagaag tgaaatactt catcttagca ttcattgggt cttctatgtt
     9001 agaccattcc aactgttctt cagatttcca ttctaggaat tgaccgtatt cgctacccat
     9061 gaagagcaat ttcttaccag ggtgacaaat ttggtacgta tagagattgc gcaagcctgc
     9121 aaattgattg taacgatctc cccacatctt atgcatcata ctcttcttgc catgaaccac
     9181 ttcatcgtgc gagaatggca agagataatt ctccttgaaa acatacataa agctgaaagt
     9241 caccaggtta aagtcatatt tacgatagat cggatcttct tcgtagaaac ggaggatatc
     9301 attcatccag cccatgttcc atttgtagtc aaatcctaga ccaccaatct ctttcattcc
     9361 cgtaatcttg gtcgcagacg aactttcttc tgcaatcatc atcacatctg gatattctaa
     9421 cttaataacc tcattcaagc gctgaaggaa ataataacct tcatagttga gatttccgcc
     9481 atctttatta ggtgtccatg gagcatcatc atagtccaaa tagagcatgt tgctaacagc
     9541 atccacacga ataccatcca aatgatagac atcaatccaa tgcttaatgc aagaaattaa
     9601 gaaggactgg acttcatttt ttccaaggtc aaaattaagg gcaccccaac catggttatg
     9661 agccttatta tggtcttggt attcaaaagt cggtgtccca tcataatagg ctaaggcatc
     9721 atcgttgatg gtaaagtgac ctggtaccca gtccacaata accccaatat tatgggtatg
     9781 acactcctcg acaaaatctt gaaactcctc tggtcggcca taagcatgct ctaaagcgaa
     9841 gtaacccata agctggtacc cccaactcaa acctagtggg tgggacatca agggcataaa
     9901 ctcaatatga gtatagttca tctcaactag gtaaggaatg agttcatctt tcaattgggc
     9961 aaaactataa ggactgccat caggatttct cttccaagag ccagcatgaa cctcgtaaat
    10021 attgacagga cgttcagcaa agccccaacg ttttcttcgt gccagccaaa gtccatccct
    10081 ccatttctta tcaggaagct ctgttacgat tgcccctgtt cctggacgag cctcatacct
    10141 gacagcaaaa gggtcaatct tcatcagttg atgaccattt tgacgtgtga catgatattt
    10201 gtaaatatgc ccttcttgag ccatattggt aaagacttcc cagaccccaa agtcatttct
    10261 taccattgga atctgatttt caatccagtt ggtaaaatca ccaaccaagt gaacagcctg
    10321 agcattaggt gcccaaacac ggaaggtata gccatgctct ccatttagtt cttccctatg
    10381 tgctcctaga taatgttgga gataaaaatt ttcacccgtc ataaaggttt ttaatgcttc
    10441 tctattatcc atatactccc cttcttctgt aagcgttttc tatgttttta ttatactacc
    10501 tttttagaga agattcaagt aaattactat acttctttaa ttattttgaa aatctacaac
    10561 aagttcactt actcgttcaa ttgtaaatca atattttttc aaaaaattgc gaaaacgcct
    10621 ttctttttct actatagtga aatgaaataa aacatgcgca aatcgatcag gacag
//
LOCUS       DAVLXH010000062        10252 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00028199
            SAMN33607166-rid17955573.denovo.062, whole genome shotgun sequence.
ACCESSION   DAVLXH010000062 DAVLXH010000000
VERSION     DAVLXH010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607166
            Sequence Read Archive: SRR23725544
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10252)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10252)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721421.1
            Genome Coverage       :: 115x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:42:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,210
            CDSs (total)                      :: 2,161
            Genes (coding)                    :: 2,023
            CDSs (with protein)               :: 2,023
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 73 of 138
            Pseudo Genes (incomplete)         :: 60 of 138
            Pseudo Genes (internal stop)      :: 40 of 138
            Pseudo Genes (multiple problems)  :: 31 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10252
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607166-rid17955573.denovo.062"
                     /strain="AUSMDU00028199"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1349"
     gene            <1..156
                     /locus_tag="VYO11_001834"
     CDS             <1..156
                     /locus_tag="VYO11_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV1596343.1"
                     /translation="LLFFIINNSSSSQTNILAQLMDFFTGNGHLEDLSKISEPEKLYA
                     YIAEATA"
     gene            194..496
                     /locus_tag="VYO11_001835"
     CDS             194..496
                     /locus_tag="VYO11_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV1596344.1"
                     /translation="MIKILAACGAGVNSSHQIKSALEEELSNRGYDVHCDAVMVKDVN
                     EDLMKGYDIFTPIAATDLGFEPGIPVIEAGPILFRIPAMSVPVFDNIRLPAKQNMV"
     gene            504..1308
                     /locus_tag="VYO11_001836"
     CDS             join(504..872,874..1308)
                     /locus_tag="VYO11_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
                     /protein_id="HEV1596345.1"
                     /translation="MNYEASKQLTDARFKRLVGVQRTTFEEMLAVLKTAYQLKHAKGG
                     RKPKLSLEDLLMATLQYVREYRTYEQIAADFGIHESNLLRRSQWVEVTLVQSGFTISR
                     TPLSSEDTVMIDATEVKINRPKKELANDSGKKKCHAMKAQAIVTSQGRIVSLDIAVNY
                     CHDMKLFKMSRRNIGQAGKILADSGYQGLMKIYPQAQTPRKSSKLKPLTVEDKAYNHA
                     LSKDRSKVENIFAKVKTFKMFSTTYRNHRKRFGLRMNLIAGIINHELGF"
     gene            1357..1820
                     /locus_tag="VYO11_001837"
                     /pseudo
     CDS             1357..1820
                     /locus_tag="VYO11_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000883906.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="aldose epimerase"
     gene            1977..2402
                     /gene="lacA"
                     /locus_tag="VYO11_001838"
     CDS             1977..2402
                     /gene="lacA"
                     /locus_tag="VYO11_001838"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HEV1596346.1"
                     /translation="MSIVIGADAAGLRLKEVVKDFLEKENFHLVDVTAEGQDFVDVTL
                     AVAAEVNKEEQNLGIVIDAYGAGPFMVATKIKGMVAAEVSDERSAYMTRGHNNSRMIT
                     MGAQLVGDELAKNIAKGFVNGKYDGGRHQIRVDMLNKMG"
     gene            2433..2948
                     /gene="lacB"
                     /locus_tag="VYO11_001839"
     CDS             2433..2948
                     /gene="lacB"
                     /locus_tag="VYO11_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HEV1596347.1"
                     /translation="MRIAIGCDHIVTDEKMAVSEFLKSKGYEVIDFGTYDHTRTHYPI
                     FGKKVGEAVTSGQADLGVCICGTGVGINNAVNKVPGIRSALVRDMTTALYAKEQLNAN
                     VIGFGGKITGELLMCDIIEAFIHAEYKPSEENKKLIAKIEHLESHNAQQTDANFFTEF
                     LEKWDRGEYHD"
     gene            2959..3888
                     /locus_tag="VYO11_001840"
     CDS             2959..3888
                     /locus_tag="VYO11_001840"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HEV1596348.1"
                     /translation="MILTVTMNPSIDISYPLDELKIDTVNRVVDVTKTAGGKGLNVTR
                     VLSEFGDSVLATGLVGGKLGEFLVEHIDNQVKKDFFSIQGETRNCIAILHGDNQTEVL
                     EKGPEVLEQEGQDFLEHFKKLLESVEVVAISGSLPAGLPVDYYASLVELANQAGKPVV
                     LDCSGAALQAVLESPHKPTVIKPNNEELSQLLGREVSEDLDELKEVLQEPLFAGIEWI
                     IVSLGANGTFAKHGDTFYKVDIPRIQVVNPVGSGDSTVAGISSGLLHKESDAELLIKA
                     NVLGMLNAQEKMTGHVNMANYQVLYDQLIVKEV"
     gene            3890..4870
                     /gene="lacD"
                     /locus_tag="VYO11_001841"
     CDS             3890..4870
                     /gene="lacD"
                     /locus_tag="VYO11_001841"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HEV1596349.1"
                     /translation="MALTEQKRVRLEKLSDENGIISALAFDQRGALKRLMAQHQTEEP
                     TVAQMEELKVLVADELTKYASSMLLDPEYGLPATKALDEKAGLLLAYEKTGYDTTSTK
                     RLPDCLDVWSAKRIKEEGADAVKFLLYYDVDSSDELNQEKQAYIERIGSECVAEDIPF
                     FLEILAYDEKIADAGSVEYAKVKPHKVIGAMKVFSDPRFNIDVLKVEVPVNIKYVEGF
                     AEGEVVYTREEAAAFFKAQDEATNLPYIYLSAGVSAKLFQDTLVFAHESGANFNGVLC
                     GRATWAGSVEAYIKDGEAAAREWLRTTGFENIDELNKVLQTTATSWKERV"
     gene            5104..5940
                     /locus_tag="VYO11_001842"
     CDS             5104..5940
                     /locus_tag="VYO11_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HEV1596350.1"
                     /translation="MYRILNPMNHNVSLVRNDKGEEVIVIGKGIAFGKKKGDLIAENQ
                     VEKIFRMKTEESRENFMALLKDVPLDFITVTYEIIDKLSKKYHYPIQEYLYVTLTDHI
                     YCSYQALTQGRYKDSNLPDISAKYPVAFQIANEAFEIYRQKLADHFPEDEIIRIAYHF
                     INAEGENEVELVESIDKRKEILRNVEEVLTDYAIQRTKKNNHFYDRFMIHLNYFLDYL
                     DRSRDDNQSLLDMEDHIKQSYPKAFEIGSKIYDVITQHTGLDLYKSERVYLVLHIQRL
                     LS"
     gene            5976..6293
                     /locus_tag="VYO11_001843"
     CDS             5976..6293
                     /locus_tag="VYO11_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEV1596351.1"
                     /translation="MNREEVTLLGFEIVAYAGDARSKLLEALKAAEAGDFEKADALVE
                     EAGSCIAEAHHAQTSLLTKEASGEDLAYSVTMMHGQDHLMTTILLKDLMHHLIELYKR
                     GVK"
     gene            6295..7989
                     /locus_tag="VYO11_001844"
     CDS             6295..7989
                     /locus_tag="VYO11_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001037357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEV1596352.1"
                     /translation="MDKLIIFIEKGKPFFEKLSRNIYLRAIKDGFISSMPAVLFSSIF
                     ILIAAVPNIFGFKWSDEQLAFILKPYNYSMGILALLVAGTTAKSLTDSVNTRSMEKTN
                     QINYMSTFLAAVVGLLILAADPIEGGFANGLLGTRGLLTAFLAAFITVNIYKVCIKNN
                     VTIRLPEEVPPNIAQVFKDVIPFALSVLSIYGLDLIVRNIFGTNVAESVGKILAPLFS
                     ATDGYIGLAIVFGAYAFFWFVGIHGPSVVEPLIVAISYANIEANVQLVQAGMHADKIL
                     NPVTQTFVVTMGGTGATLVVPFMFMWLCKSKRNRIVGRASVVPTFFGVNEPILFGAPI
                     VLNPIFFIPFVTAPIINVWIMKFFVDVLQMNSFSIILPWTTPAPIGIVMGTALAPLSF
                     VLAITLIIIDTLIYYPFVKVYDHQILEEERKGNSSSELKEKVAANFNTAKADAILEKA
                     GVDAAQNTITEETNVLVLCAGGGTSGLLANALNKAAAEYNVPVKAAAGGYGAHREMLP
                     EFDLVILAPQVASNFEDMKAETDKLGIKLAKTEGAQYIKLTRDGKGALAFVQEQFD"
     gene            8204..9610
                     /gene="lacG"
                     /locus_tag="VYO11_001845"
     CDS             8204..9610
                     /gene="lacG"
                     /locus_tag="VYO11_001845"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HEV1596353.1"
                     /translation="MTKTLPKDFIFGGATAAYQAEGATHTDGKGPVAWDKYLEDNYWY
                     TAEPASDFYNRYPVDLKLAEEYGVNGIRISIAWSRIFPTGYGQVNAKGVEFYHNLFAE
                     CHKRHVEPFVTLHHFDTPEALHSNGDFLNRENIEHFVDYAAFCFEEFPEVNYWTTFNE
                     IGPIGDGQYLVGKFPPGIQYDLAKVFQSHHNMMVSHARAVKLYKEKGYKGEIGVVHAL
                     PTKYPLDPENPADVRAAELEDIIHNKFILDATYLGRYSAETMEGVNHILSVNGGSLDL
                     REEDFTALEAAKDLNDFLGINYYMSDWMEAFDGETEIIHNGKGEKGSSKYQIKGVGRR
                     VAPDYVPRTDWDWIIYPQGLYDQIMRVKKDYPNYKKIYITENGLGYKDEFVDNTVYDD
                     GRIDYVKQHLEILSDAIADGANVKGYFIWSLMDVFSWSNGYEKRYGLFYVDFETQERY
                     PKKSAHWYKKVAETQIID"
     gene            9653..9790
                     /locus_tag="VYO11_001846"
     CDS             9653..9790
                     /locus_tag="VYO11_001846"
                     /inference="COORDINATES: protein motif:HMM:NF024424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3884 family protein"
                     /protein_id="HEV1596354.1"
                     /translation="MFKDFIQSIYEKVYIINFEKCSQIPCLTSEELKSLGKWYVSTGK
                     E"
     gene            9791..9904
                     /locus_tag="VYO11_001847"
     CDS             9791..9904
                     /locus_tag="VYO11_001847"
                     /inference="COORDINATES: protein motif:HMM:NF024424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3884 family protein"
                     /protein_id="HEV1596355.1"
                     /translation="MCHSDADLEEFKNLFLNFINPEEWDTISFDSDFMPFQ"
BASE COUNT         3304 a         1753 c         2096 g         3099 t
ORIGIN      
        1 ttgctcttct ttatcatcaa taactcaagt tcaagtcaaa caaatattct ggctcagttg
       61 atggactttt tcacaggaaa tggacatctt gaagatctat caaaaatttc cgaaccagaa
      121 aaactttatg cttacattgc tgaagcaacc gcttaatctt gtctattaaa aaataaaatc
      181 ggaggaaatc caaatgatta aaattcttgc tgcctgcggt gcaggtgtta actcaagtca
      241 ccaaattaaa agtgctctag aagaagaact ttcaaaccgt ggttacgatg ttcactgtga
      301 tgcagttatg gtgaaagatg taaacgaaga ccttatgaaa ggttacgata tctttacacc
      361 aatcgctgca acagaccttg gttttgaacc aggtatccca gttatcgaag ctgggccaat
      421 cttattccgt atcccagcaa tgagcgttcc agtatttgac aatattagac ttcctgcgaa
      481 acaaaatatg gtatagtagt tccatgaatt atgaagcaag taaacaacta actgatgcac
      541 gatttaagcg tcttgttggt gttcagcgta ccacttttga agagatgtta gctgtattaa
      601 aaacagctta tcaacttaaa cacgcaaaag gtggacgaaa acctaaatta agcctagaag
      661 accttcttat ggccactctt caatatgtgc gagaatatcg aacttatgaa caaattgcgg
      721 ctgattttgg tattcacgaa agcaacttac tccgtcggag ccaatgggtt gaagtaactc
      781 ttgttcaaag tggttttacg atttcaagaa ctcctctcag ttctgaggac acggtaatga
      841 ttgatgcgac ggaagtaaaa atcaatcgcc ctaaaaaaag aattagcgaa tgattctggt
      901 aaaaagaaat gccacgctat gaaggctcaa gcgattgtca caagtcaagg gagaattgtt
      961 tctttggata tcgctgtgaa ctattgtcat gatatgaagt tgttcaaaat gagtcgcaga
     1021 aatatcggac aagctggaaa aatcttggct gacagtggtt atcaagggct catgaagata
     1081 tatcctcaag cacaaactcc acgtaaatcc agcaaactca agccgctaac agttgaagat
     1141 aaagcctata accatgcgct atccaaggat agaagcaagg ttgagaacat ctttgccaaa
     1201 gtaaaaacgt ttaaaatgtt ttcaacaacc tatcgaaatc atcgtaaacg cttcggatta
     1261 cgaatgaatt tgattgctgg cattatcaat catgaactag gattctagtt ttgcaggaag
     1321 tctaataaag aaactagcaa ggtcaggcct tactttattg gtggacatcc aggatttaat
     1381 tgtcctctac ttgatgatga agtctatgaa gattattatc tagagtttga gaaagaagag
     1441 atttgctctg ttccacgtcc tttcccagaa acaggtatgt tggatttcca agatagaagt
     1501 ccatggctag agggacaaaa agaaatagat cttagttatg atcttttcag cacagatgca
     1561 gtgactttgg atgaattgca atctcgaaca attgcccttc gttctcttaa acatgataag
     1621 ggattgaaag tgcattttgc agaatttcca aacctcatca tctggtcaac tttgaacaag
     1681 ggacctttca ttacctttga accatggtct ggcttgtcaa cattcttgaa gaaggagatc
     1741 atttagaaga taagaagaat gtttgtctct tagaagccaa tcaggttgaa gaattagggt
     1801 ttgagataga agttttataa aaaagtaaaa aataaataac aaaaacaaac acaaactatt
     1861 gacttcttca aacaatagta gtatattatg tttgtgagga ctaattgact gttttttaaa
     1921 gatagccaat acactgctgg aatccagcat agaaaaaata aaaaggagta tacaatatgt
     1981 ctattgttat cggtgcagat gctgcaggtt tgagattgaa agaagttgtg aaagacttct
     2041 tagaaaaaga aaacttccac cttgtggatg ttacagctga aggtcaagac tttgttgatg
     2101 tgactctcgc tgttgctgca gaagtaaaca aagaagaaca aaaccttggt atcgtgattg
     2161 atgcttatgg agctggtcca tttatggttg caactaagat caaaggaatg gttgctgcag
     2221 aagtatctga cgaacgttca gcttatatga ctcgtggcca caacaactca cgtatgatca
     2281 ctatgggggc acaacttgtt ggtgatgaat tggctaaaaa tatcgctaaa ggatttgtta
     2341 acggtaaata cgacggtggt cgtcaccaaa ttagggtcga catgttgaac aaaatgggct
     2401 aattagatta tagtaagaaa ggtaagttaa aaatgagaat tgcaattgga tgtgaccaca
     2461 tcgtaacaga tgaaaaaatg gcggtttcag aatttttgaa atcaaaagga tatgaagtca
     2521 ttgactttgg tacctatgac catacacgta ctcactaccc aatctttggt aaaaaagtag
     2581 gggaagcagt aactagtggt caagctgatc tcggggtatg tatctgtggt actggtgttg
     2641 gtatcaacaa cgctgtaaat aaagttccag gtattcgttc tgccttggtt cgtgatatga
     2701 caacagccct ttatgctaaa gaacaattga acgccaacgt tatcggtttt ggtggtaaga
     2761 ttactggtga attgcttatg tgtgatatca tcgaagcttt cattcatgct gaatacaaac
     2821 catctgaaga aaacaaaaaa ttgattgcga aaattgaaca ccttgaaagt cacaatgctc
     2881 aacaaacaga cgcaaacttc ttcactgaat tccttgaaaa atgggatcgc ggagaatacc
     2941 acgactaaga ggtaacctat gattttaaca gttacaatga acccatccat tgatatttcc
     3001 tatcccttgg atgagttgaa gattgatact gtcaatcgtg tggtggatgt aaccaaaacg
     3061 gctggtggta agggactcaa tgttacccga gtactttcag aatttggcga ttctgttctt
     3121 gctactggtt tagtgggtgg caaacttggt gagtttttgg ttgaacatat cgataatcaa
     3181 gtaaagaaag atttcttctc aattcaggga gaaactcgta actgtatcgc tattctccac
     3241 ggagacaacc aaacagaagt tcttgaaaaa ggtcctgaag tattggaaca ggaaggtcaa
     3301 gactttttgg aacatttcaa aaaactcttg gagtcagttg aagtagtggc catctcaggt
     3361 agtctgccag ctggccttcc agttgattac tatgcgagct tggtagaact tgctaatcaa
     3421 gctggcaagc ctgtagtctt ggactgctca ggtgcagcac ttcaggctgt tcttgaatca
     3481 ccccataaac caacagtcat caaaccaaat aatgaagaat tgtctcagct tcttggaaga
     3541 gaagtttctg aggatttgga tgaattaaaa gaagtacttc aagaaccttt gtttgcaggg
     3601 attgaatgga ttatcgtttc acttggtgcc aacggtactt ttgccaaaca tggtgacact
     3661 ttctacaagg tagatattcc tagaattcag gtggtaaatc ctgttggatc tggagactct
     3721 actgtggcag gaatttcttc aggacttctt cacaaagaat cggatgcaga attactcatc
     3781 aaggcaaatg tccttggtat gctcaatgct caagaaaaaa tgactggtca tgtcaacatg
     3841 gccaactatc aagttctata tgatcaatta atagtaaaag aggtataaaa tggctttaac
     3901 agaacaaaaa cgtgtacgct tagaaaaact ttctgatgaa aatggtatca tctcagctct
     3961 tgcatttgac caacgtggtg ctttgaaacg cctcatggct caacaccaaa cagaagaacc
     4021 aactgtggcc caaatggaag aacttaaagt cttggtagca gatgaattga ctaaatacgc
     4081 ttcatctatg cttcttgacc ctgagtatgg acttccagca actaaggctc ttgatgaaaa
     4141 agctggtctt ctccttgctt atgaaaaaac aggttatgac acaacaagca caaaacgctt
     4201 gccagactgc ttggatgtct ggtctgcaaa acgtattaaa gaagaaggtg cagatgcagt
     4261 taaattcttg ctttactatg atgtagatag ctcagacgaa ctcaatcaag aaaaacaagc
     4321 ctacatcgaa cgcatcggtt ctgagtgtgt ggctgaagat atcccattct tccttgaaat
     4381 tcttgcttac gatgaaaaaa ttgcggatgc aggttctgta gaatacgcga aagtaaaacc
     4441 acacaaagtt attggcgcta tgaaagtctt ttcagaccca cgctttaaca ttgatgtctt
     4501 gaaagttgaa gttcctgtta acattaaata tgttgaaggc ttcgctgaag gtgaagtagt
     4561 ttatacacgt gaagaagcag cagccttctt caaagcgcaa gatgaagcaa cgaacttgcc
     4621 atacatctac ttgagtgctg gtgtatcagc taaactcttc caagatactc ttgtatttgc
     4681 tcatgaatca ggtgcaaact ttaacggagt tctttgtggc cgtgctacat gggcagggtc
     4741 agttgaagct tacatcaaag atggtgaagc agcagctcgc gaatggcttc gcacaactgg
     4801 atttgaaaac attgatgagc tcaataaagt tcttcaaaca acagcgactt catggaaaga
     4861 acgtgtgtaa gaaagtcctc ctagtttagg aacatgaatc taaaaaaatt taaaaaaagt
     4921 tgtatgtaaa ggtttacaaa ataacttact tgtgctatac ttaaatcaca agttaataca
     4981 aggtgagtgt tactaagtaa tattaggcat gatcacaggt gaattagaaa tcagctgatt
     5041 ttctagttca tttgtggtca ttttttgtac ttatatacct ttaagatata aaaggaggtt
     5101 gacatgtatc gaattctaaa tccaatgaat cacaatgtct cgcttgtcag aaatgataag
     5161 ggagaagagg tgattgtaat tggtaagggg attgcattcg gaaagaagaa gggggatttg
     5221 attgctgaaa atcaggttga gaaaatcttt cggatgaaga ccgaagagtc cagagaaaac
     5281 tttatggctc ttctcaaaga tgttccgctt gattttatca cagtgaccta tgaaatcatt
     5341 gataagctat caaagaaata tcattatccg attcaagagt atctctatgt aaccttgaca
     5401 gatcatattt actgttctta tcaagctcta actcaaggaa ggtacaagga tagtaatctg
     5461 ccagatattt ctgctaagta tcctgtcgct tttcaaatcg caaatgaagc ttttgaaatt
     5521 taccgtcaga agctagcaga tcattttcct gaggacgaaa ttattcggat tgcttatcat
     5581 ttcattaatg ctgaaggtga aaatgaagtg gaacttgtgg agtcgattga taagaggaaa
     5641 gaaattctca ggaatgttga agaagtttta acggactatg caattcaacg aactaaaaag
     5701 aataaccatt tctatgatcg ctttatgatc catttgaatt atttcttgga ttatttagac
     5761 agatctagag atgataacca atcacttctg gatatggaag atcatattaa acaatcctat
     5821 ccaaaagcct tcgagattgg ttccaagatc tatgatgtga ttacgcaaca tacgggtctt
     5881 gatttgtata aaagtgaacg agtttatcta gttctacata tccaacgttt attgtcataa
     5941 aaatttattt aaaactatat aaggagaatt ctatcatgaa tagagaagaa gtaacattgt
     6001 taggttttga aatcgtagcc tatgctggcg atgctcgttc aaaactattg gaagccttga
     6061 aggctgctga agctggtgat tttgaaaaag cggacgctct ggtagaggaa gctggtagct
     6121 gtattgcaga ggctcaccac gcgcaaacaa gtctattgac taaggaagct tctggtgagg
     6181 acttagcgta tagtgtgacc atgatgcatg gtcaagatca cttgatgaca actatcttgt
     6241 taaaagacct aatgcaccat ttaattgaac tttacaagag aggagttaaa taaaatggat
     6301 aagttaataa tttttattga gaaaggaaag cctttctttg agaaattatc gagaaatata
     6361 tacttaagag cgataaaaga tggttttatt tccagtatgc cagcagtatt attctcaagt
     6421 atttttatac taatagctgc tgtgcccaat atttttgggt ttaaatggtc tgatgaacag
     6481 ttagctttta ttttgaaacc ttacaactac tcaatgggga ttttagctct cttagtagct
     6541 gggacaactg caaaatcgtt aacagattca gttaatacac gtagtatgga gaaaaccaac
     6601 caaatcaact acatgtcaac ttttttagca gctgttgttg gattgttaat actggcagct
     6661 gatccaattg aaggtggatt tgctaatggt cttttaggta ctagaggatt acttactgca
     6721 tttttggcag cttttattac agtaaatatc tataaagtat gtattaaaaa taatgtaacc
     6781 attagacttc ctgaagaggt tccaccaaat attgcacaag tttttaaaga tgttattccg
     6841 tttgccttat ctgttctttc aatatatgga ttggatttaa ttgttagaaa tatttttggt
     6901 acaaatgtag cagaatctgt tggtaaaata ttagcccctc tattttcagc tactgatggt
     6961 tatatcggtt tagctattgt atttggtgct tatgctttct tttggtttgt tggaattcat
     7021 gggccatctg ttgtagaacc tttaattgta gctatcagtt atgcaaatat agaagctaat
     7081 gttcagcttg tgcaagctgg tatgcacgca gataaaattt taaatccagt tactcaaact
     7141 tttgttgtaa caatgggtgg tactggtgca acactagtag ttccatttat gtttatgtgg
     7201 ttatgtaaat caaaaagaaa tagaattgtc ggacgtgcgt ctgtagttcc tactttcttt
     7261 ggcgtaaatg aaccaatcct atttggtgct ccaattgttt taaatcctat cttctttatt
     7321 ccgtttgtta ctgctcctat tatcaatgtt tggattatga aattttttgt agatgttcta
     7381 caaatgaata gtttcagtat tattttacct tggacaacac ctgctccaat tggtattgtt
     7441 atgggaacgg cgctggctcc attgtcattc gtcttggcta taactttaat cattatcgac
     7501 actttaatct attatccatt tgttaaagtt tatgaccatc aaattttaga agaagaacgg
     7561 aaaggaaact cttcatctga attgaaagaa aaagttgctg caaacttcaa cactgcaaaa
     7621 gcggatgcta ttcttgaaaa agcgggtgtc gatgcagcac aaaataccat cactgaagaa
     7681 acaaatgtcc tcgttctctg tgcaggtgga ggtacaagtg gtctccttgc aaatgctttg
     7741 aataaggcag cagcagaata caatgtccct gtgaaagcag cagcaggcgg ctatggtgct
     7801 caccgtgaaa tgttgccaga gtttgatttg gttatccttg ctcctcaagt tgcttcaaac
     7861 tttgaagata tgaaggcaga aacagataag ctcggtatta aacttgctaa gacagaaggc
     7921 gctcaataca tcaaattaac tcgtgatgga aaaggtgccc tagcattcgt acaagagcaa
     7981 ttcgattaag gctaggaact gtgaaacagt ctcccatcgt tacggaaatc gctatggcga
     8041 atttcctaat cgccttatta attcgtcggt aaaaagatat cgtttttacc tcctcatgtc
     8101 acaattcagt gacttggtac aagaagtgag atggagaagc atggctcact gactcctctc
     8161 ctctcacttt tactttattt aaatcaagaa ataggtgaaa aaaatgacaa aaacacttcc
     8221 aaaagacttt attttcggtg gcgcaacagc tgcttatcaa gcagaaggtg ctacacatac
     8281 tgatggaaaa ggaccagttg cttgggataa atatcttgag gataactact ggtacactgc
     8341 cgaaccagct agtgattttt acaatcgata tccagttgac ctcaagctag cagaagagta
     8401 tggtgtcaat ggtattcgaa tttctattgc ttggtcacgt attttcccga ctggttacgg
     8461 ccaagtaaat gctaaaggtg ttgagtttta tcataattta tttgcagagt gtcacaaacg
     8521 tcatgttgag ccttttgtaa ctcttcatca ctttgacacg ccagaagctc tccactcaaa
     8581 tggagacttc ttaaaccgtg aaaatatcga acattttgta gactacgctg ccttctgttt
     8641 tgaagaattt ccagaagtaa actattggac aacctttaat gaaattggac caatcggtga
     8701 tggtcaatat ttggttggga aattccctcc aggtatccag tacgaccttg ccaaagtctt
     8761 tcaatcacac cacaatatga tggtgtctca tgcacgcgcg gtaaaattgt acaaagagaa
     8821 aggctataaa ggggaaattg gtgttgttca cgccctgcct actaaatatc ctctagatcc
     8881 tgaaaatcca gcagatgttc gtgcagctga gttggaagat atcatccaca ataaattcat
     8941 cttagacgca acttatctag gtcgctattc agctgaaacc atggaaggtg tcaaccatat
     9001 cttatcagtc aatggtggta gtttggatct tcgtgaagaa gattttacag cattagaagc
     9061 tgcaaaagac ttgaatgatt tcctaggaat caactactat atgagtgact ggatggaagc
     9121 ctttgatgga gaaactgaaa ttatccataa tggtaaaggt gaaaaaggaa gctctaagta
     9181 tcaaatcaaa ggtgttggtc gtcgtgtagc tcctgactat gtaccacgca cggattggga
     9241 ttggattatc taccctcaag gtttgtatga ccaaatcatg cgtgtgaaga aagattatcc
     9301 taactacaag aagatttaca tcactgaaaa tggtctcggc tataaagatg agttcgttga
     9361 taacactgtt tacgatgatg gtcgtattga ttacgtgaaa caacacttgg agatcttgtc
     9421 tgatgcgatt gcagatggag ctaatgtaaa aggttacttc atttggtcat taatggatgt
     9481 cttctcatgg tcaaacggtt atgagaaacg ttatggtctc ttctacgtag attttgaaac
     9541 tcaagaacgt tatcctaaga aatcagctca ctggtacaag aaagtagcgg aaactcagat
     9601 tatagactag tagaattagt cattagatat agaattttag taagtcaaaa agatgttcaa
     9661 agattttatc caatctattt atgaaaaagt ttatattata aatttcgaaa aatgctctca
     9721 aataccgtgt ttgacgagtg aagaattgaa aagtcttgga aaatggtatg tctcgactgg
     9781 taaagaatga atttgtcatt cagatgctga tctggaagaa tttaaaaatc tatttttaaa
     9841 ttttatcaat cctgaagaat gggatactat ctcctttgat tcagatttta tgccgtttca
     9901 ataatcgtaa ccaatttctc aaaaaagtta aatcttatat ttagtactct gtaaaactct
     9961 tatctaatca cgttgcttat actcaatgaa aatcaaagag caactttaaa ctaggaagcg
    10021 agtcgcagat ttctcaatgt atagctttga ggaattgggc aaaaagtctt tgatatagaa
    10081 aaaagcatag tatcaggtgt tgaaacacct gatactatgc tttttattgt gggaagattt
    10141 actttttttc ttctgaaatt gagttgttac ccaggctctt tcagtttatt aaggcttgat
    10201 gactttaatg tgtttagata gcttaaaaag gattgaatca cttagtttag aa
//
LOCUS       DAVLXH010000063        10220 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00028199
            SAMN33607166-rid17955573.denovo.063, whole genome shotgun sequence.
ACCESSION   DAVLXH010000063 DAVLXH010000000
VERSION     DAVLXH010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607166
            Sequence Read Archive: SRR23725544
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10220)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10220)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721421.1
            Genome Coverage       :: 115x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:42:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,210
            CDSs (total)                      :: 2,161
            Genes (coding)                    :: 2,023
            CDSs (with protein)               :: 2,023
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 73 of 138
            Pseudo Genes (incomplete)         :: 60 of 138
            Pseudo Genes (internal stop)      :: 40 of 138
            Pseudo Genes (multiple problems)  :: 31 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10220
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607166-rid17955573.denovo.063"
                     /strain="AUSMDU00028199"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1349"
     gene            <1..238
                     /locus_tag="VYO11_001848"
     CDS             <1..238
                     /locus_tag="VYO11_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV1596356.1"
                     /translation="KGIQASMSRKGNSPDNGMMESFFGILKSEMFYGYEKNFRSLENL
                     EQAIVDYIDYYNNKRIKVKLKGLSPVQYRTKSFG"
     gene            complement(283..924)
                     /gene="plsY"
                     /locus_tag="VYO11_001849"
     CDS             complement(283..924)
                     /gene="plsY"
                     /locus_tag="VYO11_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HEV1596357.1"
                     /translation="MITIVLLILAYLLGSIPSGLWIGQVFFQINLREHGSGNTGTTNT
                     FRILGKKAGMATFVIDFFKGTLATLLPIIFHLQGVSPLIFGLLAVIGHTFPIFAGFKG
                     GKAVATSAGVIFGFAPIFCLYLAIIFFGALYLGSMISLSSVTASIAAVIGVLLFPLFG
                     FILSNYDSLFITIILALASLIIIRHKDNIARIKNKTENLVPWGLNLTHQDPKK"
     gene            1060..3003
                     /gene="parE"
                     /locus_tag="VYO11_001850"
     CDS             1060..3003
                     /gene="parE"
                     /locus_tag="VYO11_001850"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HEV1596358.1"
                     /translation="MSKKEININNYNDDAIQVLEGLDAVRKRPGMYIGSTDGAGLHHL
                     VWEIVDNAVDEALSGFGDRIDVTINKDGSLTVQDHGRGMPTGMHAMGIPTVEVIFTIL
                     HAGGKFGQGGYKTSGGLHGVGSSVVNALSNWLEVEITRDGAVYKQRFENGGKPVTTLK
                     KIGTAPKSKTGTKVTFMPDATIFSTTDFKYNTISERLNESAFLLKNVTLSLTDKRTDE
                     AIEFHYENGVQDFVSYLNEDKEILTPVLYFEGEDNGFQVEVALQYNDGFSDNILSFVN
                     NVRTKDGGTHETGLKSAITKVMNDYARKTGLLKEKDKNLEGSDYREGLAAVLSILVPE
                     EHLQFEGQTKDKLGSPLARPVVDGIVADKLTFFLMENGELASNLIRKAIKARDAREAA
                     RKARDESRNGKKNKKDKGLLSGKLTPAQSKNPAKNELYLVEGDSAGGSAKQGRDRKFQ
                     AILPLRGKVVNTAKAKMADILKNEEINTMIYTIGAGVGADFSIEDANYDKIIIMTDAD
                     TDGAHIQTLLLTFFYRYMRPLVEAGHVYIALPPLYKMSKGKGKKEEVAYAWTDGELEE
                     LRKQFGKGATLQRYKGLGEMNADQLWETTMNPETRTLIRVTIEDLARAERRVNVLMGD
                     KVEPRRKWIEDNVKFTLEEATVF"
     gene            3423..5894
                     /gene="parC"
                     /locus_tag="VYO11_001851"
     CDS             3423..5894
                     /gene="parC"
                     /locus_tag="VYO11_001851"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HEV1596359.1"
                     /translation="MSNIQNMSLEDIMGERFGRYSKYIIQDRALPDIRDGLKPVQRRI
                     LYSMNKDSNTFDKSYRKSAKSVGNIMGNFHPHGDSSIYDAMVRMSQNWKNREILVEMH
                     GNNGSMDGDPPAAMRYTEARLSEIAGYLLQDIEKNTVPFAWNFDDTEKEPTVLPAAFP
                     NLLVNGSTGISAGYATDIPPHNLAEVIDAAVYMIDHPTAKIDKLMEFLPGPDFPTGAI
                     IQGRDEIKKAYETGKGRVVVRSKTEIEKLKGGKEQIVITEIPYEINKANLVKKIDDVR
                     VNNKVAGIAEVRDESDRDGLRIAIELKKDANTELVLNYLFKYTDLQINYNFNMVAIDN
                     FTPRQVGIVPILSSYIAHRREVILARSRFDKEKAEKRLHIVEGLIRVISILDEVIALI
                     RASENKADAKENLKVSYDFTEEQAEAIVTLQLYRLTNTDVVVLQEEEAELREKIAMLA
                     AIIGDERTMYNLMKKELREVKKKFATPRLSSLEDTAKAIEIDTASLIAEEDTYVSVTK
                     AGYIKRTSPRSFAASTLEEIGKRDDDRLIFVQSAKTTQHLLMFTSLGNVIYRPIHELA
                     DIRWKDIGEHLSQTITNFETNEEILYVEVLDQFDDATTYFAVTRLGQIKRVERKEFTP
                     WRTYRSKSVKYAKLKDDTDQIVAVAPIKLDDVVLVSQNGYALRFNIEEVPVVGAKAAG
                     VKAMNLKEDDVLQSGFICNTSSFYLLTQRGSLKRVSIEEILATSRAKRGLQVLRELKN
                     KPHRVFLAGAVAEQGFVGDFFSTEVDVNDQTLLVQSNKGTIYESRLQDLNLSERTSNG
                     SFISDTISDEEVFDAYLQEVVTEDK"
     gene            6026..7048
                     /locus_tag="VYO11_001852"
     CDS             6026..7048
                     /locus_tag="VYO11_001852"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HEV1596360.1"
                     /translation="MTVTIDWENLGFSYMKLPYRYLAHFKNGQWDQGELTEDATLHIS
                     ESSPSLHYGQQAFEGLKAYRTKDGSVQLFRPDENAKRLQRTCDRLLMPQVPTDMFVEA
                     CKAVVRANEEYVPPYGIGGTLYLRPLLIGVGDIIGVKPAEEYIFTIFAMPVGNYFKGG
                     LVPTNFLIQDEYDRAAPNGTGAAKVGGNYAASLLPGKMAKSRHFSDVIYLDPSTHTKI
                     EEVGSANFFGITADNEFVTPLSPSILPSITKYSLLYLAEHRLGLTPIEGDVPIDNLDR
                     FVEAGACGTAAVISPIGGIQHGDDFHVFYSETEVGPVTRKLYNELTGIQFGDIEAPEG
                     WIVKVD"
     gene            7104..7808
                     /locus_tag="VYO11_001853"
     CDS             7104..7808
                     /locus_tag="VYO11_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV1596361.1"
                     /translation="MVLSTSAILVACGKTDKEADAPTTFSYVYAVDPASLGYSIATRT
                     SRTDVIGNVIDGLMENDKYGNVAPSQKDYDLNSTGWAPSYQDPASYLNIMDPKSGSAM
                     KHLGITKGKDKDVVAKPGLDKYKKLLEDAVSETTDLEKRYEKYAKAQAWSTDSSLLMP
                     TASSGGSPVVSNVVPFSKPYSQVGIKGEPYIFKGMKLQKDIVTTKEYNEVFKKWQKEK
                     LESNSKYQKELEKYIK"
     gene            7873..8562
                     /locus_tag="VYO11_001854"
     CDS             7873..8562
                     /locus_tag="VYO11_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HEV1596362.1"
                     /translation="MEWIRLIGIAIIVVGFILKFDTIATVVLAGLVTALVSGVSLVEF
                     LEILGKEFSNQRVLTIFMVTLPLVGLSETFGLKQRSIDLIRKIKGLTVGNFYTVYFFI
                     RELAGFFSIRLGGHPQFVRPLVQPMGEAAAESQLGRKLTEVEDETIKARAAANENFGN
                     FFAQNTFVGAGGVLLIGGTLDQLGYESNYAGIASTSIIVAVITLIVVGIYNYLFDKKL
                     ISKKTRGGEQK"
     gene            8559..9482
                     /locus_tag="VYO11_001855"
     CDS             8559..9482
                     /locus_tag="VYO11_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HEV1596363.1"
                     /translation="MTELAKQLLELTYIVIGCQFLHTAYCSYKDKTNPVRLGTSAFWT
                     LLSITFIGGSYMPNMSIGIIVILLSLLTLFKQVRIGTLPSLDEMKANIESNRLKNKIF
                     IPVMLMAILALVLAQMIPEFSKISISLAALFATISVLVITNSHPKSLLSENNRMTQQV
                     STSGIVPQLLGALGAIFTVAGVGDVISHLISGIVPSDSRFIGVLAYVLGMVLFTMIMG
                     NAFAAFTVITAGVGVPFVFALGANPIVAGALAMTAGYCGTLLTPMAANFNALPAALMD
                     MKDQNGVIKAQAGVALVMIVIHIFLMYFLAF"
     gene            9497..10141
                     /gene="pcp"
                     /locus_tag="VYO11_001856"
     CDS             9497..10141
                     /gene="pcp"
                     /locus_tag="VYO11_001856"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HEV1596364.1"
                     /translation="MKILVTGFNPFGGEKINPALEAVKLLPSEINGAEVRWVEIPTVF
                     YKSSEVLEAEILRYQPDAVLCIGQAGGRTGLTPERVAINQDDARIPDNEGNQPIDTPI
                     RIDGASAYFSSLPIKAMVQAIKKQGLPAVVSNSAGTFVCNHLMYQALYLVDKKFPNMR
                     AGFMHIPYMMEQVVNKPNTAGMSLCDIVRGIEVAIEAIVDYKDKDLQLVGGETH"
BASE COUNT         3154 a         1837 c         2306 g         2923 t
ORIGIN      
        1 taagggaatt caagcatcta tgtcacgcaa gggaaacagc ccagacaacg gcatgatgga
       61 atctttcttt ggcattttga aatcggagat gttttatggt tatgagaaga actttagatc
      121 tttagaaaac cttgaacaag ctattgtgga ctatattgat tactacaaca ataaacgaat
      181 taaggtaaaa ctaaaaggac ttagccctgt gcaatacaga actaaatcct tcggataaat
      241 taattgtcta acttttgggg tgcagttcac agaactggca ttttattttt taggatcttg
      301 atgggttaag ttcaatcccc aagggaccaa attttcagtt ttatttttga tacgagctat
      361 attgtcctta tgacgaatga taatcaaact agcaagtgct aagataatag tgatgaagag
      421 agagtcatag ttactcagga taaaaccaaa aagtggaaag agcagaaccc cgataacagc
      481 cgcaatcgat gctgtgacac tagacaatga aatcatactg ccaagataga gagctccaaa
      541 gaagataatc gcaaggtaga gacagaagat aggcgcaaat ccgaaaatca ctccagcact
      601 ggttgcgaca gccttaccac ctttaaatcc tgcaaagata gggaaggtat ggccgataac
      661 agccaaaagt ccaaagatga gaggagaaac gccttgtaga tgaaaaataa tcggaagcag
      721 cgttgctagg gttcctttga aaaagtcaat cacaaaggtt gccataccag ctttcttacc
      781 taaaatgcgg aaggtgttgg tcgttccagt gttaccagaa ccatgctcgc gtagattgat
      841 ttgaaagaat acttgtccaa tccagagacc agatggaatc gaacccagca gataggctag
      901 gattaataaa actattgtaa tcatactcct attatatcat gaattgggaa agaaaagcag
      961 agaatctctg ctgaaattgt cacatcggag aaagaaaaat tttgcaaaat ccttggaaaa
     1021 cctgtagaat agtaaagatg aacgaatagg aggttccttg tgtcaaaaaa ggaaatcaat
     1081 attaacaatt ataatgatga tgctattcag gtgctagaag ggttggatgc ggtccgaaaa
     1141 cgtccaggga tgtatattgg atcgaccgat ggcgctggtc ttcatcacct agtttgggaa
     1201 atcgttgata atgcagtcga tgaagccttg tctgggtttg gtgatcgtat tgatgtaact
     1261 atcaataaag acggtagtct aacggttcaa gaccatggac gtgggatgcc gacaggtatg
     1321 cacgctatgg gaattccaac tgttgaggtt atctttacca ttcttcatgc cggagggaaa
     1381 ttcggtcaag gtggctataa gacatcaggt ggacttcacg gagtgggttc ttccgttgtt
     1441 aacgcccttt ctaactggtt agaagttgaa attacccgtg atggtgcagt ttacaagcaa
     1501 cgtttcgaaa atggtggaaa acctgtcacg actttgaaga aaatcggtac agcacccaag
     1561 tctaaaacag gcaccaaagt tacttttatg cctgacgcga ctatcttttc tacgacagat
     1621 ttcaagtaca ataccatttc agagcgcctt aatgaatcag cctttctctt gaaaaatgtg
     1681 accttgtctt taacggacaa gcgaacagat gaagcgattg agttccacta tgagaatgga
     1741 gtacaagatt ttgtttctta tctcaacgaa gataaggaaa tcttgacgcc agttctttac
     1801 tttgaagggg aagacaatgg ttttcaagtg gaagtagccc tccagtacaa tgacggattc
     1861 tcagataaca ttctatcctt tgtcaataac gttcgcacca aggacggtgg aacgcacgag
     1921 acaggactca agtctgccat taccaaggtc atgaatgact atgcacgtaa aacaggtctt
     1981 ctcaaggaaa aagataaaaa ccttgaaggt tcagactatc gtgagggact agcggccgtt
     2041 ctttctatct tagttcctga agaacacttg cagtttgaag gacagaccaa ggataaacta
     2101 ggaagccccc tagctcgccc agttgtggat ggaatagtgg ctgataagtt gacctttttc
     2161 cttatggaaa atggggaatt agcttctaac ctcatccgca aggctatcaa ggcccgtgat
     2221 gctcgtgaag cagcacgtaa ggcgcgtgat gagagccgaa atgggaagaa aaacaagaaa
     2281 gataagggct tgttgtctgg gaaattgacc ccagcccaat ctaagaatcc tgctaagaat
     2341 gaactctatc tagttgaggg ggactctgcc ggtggttctg ccaaacaagg tcgtgaccgc
     2401 aagttccagg ctattctacc tcttcgtggt aaggttgtca atacagccaa ggccaagatg
     2461 gcggatatcc tcaaaaatga agagattaat accatgattt ataccattgg tgcgggtgtt
     2521 ggagcagact tctctattga agatgccaac tatgataaga tcattatcat gaccgatgcg
     2581 gataccgacg gtgcccatat ccagaccttg ctcttgacat ttttctaccg ttacatgcgt
     2641 ccgctagtcg aggcaggtca tgtctatatt gccctcccac ctctttataa gatgtccaaa
     2701 ggtaaaggca agaaagaaga agtggcctac gcttggacgg acggagaact agaagaactc
     2761 cgtaaacagt tcggtaaagg cgctaccctc caacgataca aaggacttgg tgagatgaat
     2821 gcggaccagc tctgggaaac aaccatgaac ccagaaacac gtaccctcat ccgtgtcaca
     2881 attgaagatt tagcgcgcgc cgaacgccgc gtcaatgttc tcatgggaga taaggtagaa
     2941 ccacgccgta aatggattga agataatgtc aagtttacgc tagaagaagc gacagtgttt
     3001 taatgaaaga aaataatatg ttagtaaact ggaaattaga gtcggatgtg aatgactatg
     3061 tgaaaaagca gtttgaaaat cttggtttga aaaaattgca ggattattaa tgaagaatct
     3121 gctatgagtg cttatctcaa agaggcgctt aagggagcgg ctaagacaca aactaagact
     3181 aattttggaa aaccagattt tcatattgaa aaatacaaac aggatagttt ggttacttat
     3241 cgtaactgaa cacgggagga attcccgtaa aatatctttt actgcataaa aacctactct
     3301 acattctttg aaaggagttg aacacgccct agatactgtg tgaaaaagat aaattctctt
     3361 gtgagtttgc ttacttcaag aattttctat tttcacttgg tattttatgg gctttgtatc
     3421 ttatgtctaa cattcaaaac atgtccctgg aggacatcat gggagagcgc tttggtcgct
     3481 actccaagta cattattcaa gaccgggctt tgccagatat tcgtgatggg ttgaagccgg
     3541 ttcagcgccg tattctttat tctatgaata aggatagcaa tacttttgac aagagctacc
     3601 gtaagtcggc caagtcagtc gggaacatca tggggaattt ccacccacac ggggattctt
     3661 ctatctatga tgccatggtt cgtatgtcac agaactggaa aaatcgtgag attctagttg
     3721 aaatgcacgg taataacggt tctatggacg gagatcctcc tgcggctatg cgttatactg
     3781 aggcacgttt gtctgaaatt gcaggttacc ttcttcagga tatcgagaaa aatacagttc
     3841 cttttgcatg gaactttgac gatacggaga aagaaccaac ggtcttgcca gcagcctttc
     3901 caaacctctt ggtcaatggt tcgactggga tttcggctgg ttatgccaca gacattcctc
     3961 cccataattt agctgaggtc atagatgctg cagtttacat gattgaccac ccaactgcaa
     4021 agattgataa actcatggaa ttcttgcctg gaccagactt ccctacaggg gctattattc
     4081 agggtcgtga tgaaatcaag aaagcttatg agactgggaa agggcgcgtg gttgttcgtt
     4141 ccaagactga aattgaaaag ctaaaaggtg gtaaggaaca aatcgttatt actgagattc
     4201 cttatgaaat caataaggcc aatctagtta agaaaatcga tgatgttcgt gttaataaca
     4261 aggtagctgg gattgctgag gttcgtgatg agtctgaccg tgatggtctt cgtatcgcta
     4321 tcgaacttaa gaaagacgct aatactgagc ttgttctcaa ctacttattt aagtacaccg
     4381 acctacaaat caactacaac tttaatatgg tggcgattga caatttcaca cctcgtcagg
     4441 ttgggattgt tccaatcctg tctagctaca tcgctcaccg tcgagaagtg attttggcgc
     4501 gttcacgctt tgacaaagaa aaggctgaga aacgtctcca tatcgtcgaa ggtttgattc
     4561 gtgtgatttc gattttggat gaagtcattg ctcttatccg tgcttctgag aataaggcgg
     4621 acgccaagga aaacctcaaa gttagctatg attttacgga agaacaggct gaggctatcg
     4681 taactttgca actgtaccgt ttgaccaata ccgatgtggt tgtcttgcag gaagaagaag
     4741 cagagcttcg tgagaagatt gctatgctgg cggctattat cggtgatgaa aggactatgt
     4801 acaatctcat gaagaaagaa cttcgtgagg tcaagaagaa atttgcaact cctcgtttga
     4861 gttctttaga agacactgcg aaagcaattg agattgatac agctagtctt atcgctgagg
     4921 aagataccta cgtcagcgtg accaaggcag gttacatcaa gcgtaccagt ccacgttcct
     4981 ttgcggcttc caccttggaa gaaattggca agcgtgatga tgaccgtttg atttttgttc
     5041 aatctgccaa gacaacccag cacctcttga tgttcacaag tcttggaaat gtcatctaca
     5101 gaccaatcca tgagttggca gatattcgtt ggaaggacat cggagagcat ctgagccaaa
     5161 ccatcacaaa ctttgaaacg aatgaagaaa tcctttatgt ggaagtactg gatcagtttg
     5221 acgatgcgac aacctacttt gcagtgactc gccttggtca aatcaaacgg gtagagcgaa
     5281 aagaattcac tccatggcgg acctatagat ctaagtctgt caagtatgct aagctcaaag
     5341 acgatacaga tcagattgta gcagtggctc cgattaaact agatgatgtt gtcttggtta
     5401 gtcaaaatgg ttatgccctg cgtttcaata tcgaagaggt tccggttgtc ggtgctaagg
     5461 cagcaggtgt caaggctatg aatttgaaag aagatgatgt cctccaatct ggctttatct
     5521 gtaatacttc gtccttctac ctcttgaccc agcgtggaag cttgaaacgt gtttccattg
     5581 aggaaattct agcaaccagc cgtgccaaac gaggattaca agtcttgcgt gagttgaaaa
     5641 acaaaccgca tcgtgtcttc ttggcaggag cagttgcaga gcaaggattt gttggcgatt
     5701 tcttcagtac ggaagtggat gtgaacgacc aaactctact tgtccaatcc aataaaggaa
     5761 caatctatga aagccgattg caagacttga acttgtcaga acgcactagc aatggaagct
     5821 tcatttctga cacgatttca gatgaagaag tttttgacgc ttatcttcag gaagtagtta
     5881 ctgaagataa ataagtgaaa tgaagaatca gttctaagag ctggttttta ttggagaaat
     5941 tttctgaaaa ttacaaaata tacttgctat tttagaaaaa tagtgtagaa tataagaaat
     6001 aggtttttag aataaggagt ggaatatgac agtaacgatt gattgggaaa acctcggttt
     6061 ttcctatatg aaattacctt atcgctatct tgctcatttc aaaaatggac aatgggatca
     6121 aggagagctt acagaggatg caactttgca tatttcagag tcttctccaa gtcttcacta
     6181 tggacaacaa gcatttgaag gtttgaaagc ttatcgtact aaggatggca gtgttcaact
     6241 gttccgtcct gatgaaaatg ctaaacgcct gcaacgtaca tgtgaccgtc tcttgatgcc
     6301 acaagttccg acagacatgt ttgtagaagc ttgtaaagca gttgtccgtg cgaatgaaga
     6361 atacgtacca ccatacggaa taggtggaac tttatatctt cgccctcttt tgattggtgt
     6421 cggagatatt atcggggtaa aaccggcaga agagtacatt ttcaccatct ttgctatgcc
     6481 agttggaaat tactttaaag gtggtttggt cccaaccaac ttcttgattc aggatgagta
     6541 cgaccgtgca gcaccaaatg gtacaggtgc ggctaaggtt ggtggaaact atgctgcaag
     6601 tctcttacca ggaaaaatgg ccaagtcacg ccatttctca gatgttatct atctggaccc
     6661 atcaactcat acaaagattg aagaagtcgg atcagctaat ttctttggaa ttacagctga
     6721 taatgaattt gtaacaccat tgagtccatc tatcttgcca tctattacca agtattcctt
     6781 gctttatttg gcagaacatc gcttgggatt aactcctatt gagggtgatg ttccaattga
     6841 taatcttgac cgttttgtag aggcaggtgc ctgtggtaca gcagcggtta tttctccaat
     6901 tggaggtatt caacatggtg atgatttcca tgtattctat agtgaaacag aagtaggtcc
     6961 tgtgacgcgt aaattatata atgaattgac gggtattcag tttggcgata ttgaagcgcc
     7021 agaaggttgg attgtaaaag tagattaaaa taaaccaaag gagatttttt atgaaataga
     7081 aaaagtggct cttaacagca ggagtggtcc tgagcacgtc agctatttta gtggcttgtg
     7141 gaaaaactga taaagaagca gatgcaccga caacattttc ttatgtctat gcagtagatc
     7201 cagcatcatt gggctacagt atagcgactc gaacatcgag gacagacgtt attggaaatg
     7261 ttattgatgg tttgatggaa aatgataaat acggcaatgt tgctccttct caaaaagact
     7321 atgatttgaa cagtacagga tgggctccaa gctatcaaga tccagcgtct tacttgaata
     7381 ttatggatcc aaaatctggt tctgccatga aacaccttgg cattacgaaa ggaaaagata
     7441 aggatgttgt agctaaacct ggtttggata aatataagaa attgttagaa gatgctgttt
     7501 ctgagaccac tgacctagag aagagatatg aaaaatatgc caaagctcaa gcttggtcga
     7561 cagatagttc attattgatg ccaacagctt catctggtgg ttctccagtt gtaagtaacg
     7621 tagtaccatt ctcaaaacca tactcacaag ttggtattaa gggggaacca tatatcttta
     7681 aaggaatgaa attgcaaaaa gatattgtta caacaaaaga atataacgag gtttttaaaa
     7741 aatggcaaaa agaaaaattg gaatccaata gcaaatacca aaaagaacta gaaaaataca
     7801 ttaaataagg aatggtattg atcttgataa aatttttaaa atactgtcat tttgaatata
     7861 aaggagtttg atatggagtg gattagatta ataggaatag caatcattgt tgtgggtttt
     7921 attttaaaat ttgatacaat tgcaacagta gtcttagctg gtttggttac agctttagtt
     7981 tcaggtgttt ctctcgttga atttttggag attttgggaa aagaatttag caatcagcga
     8041 gtgctcacga tttttatggt taccttgcct cttgtggggc tgtcagaaac ctttggactc
     8101 aagcaacgat caatcgattt gattcgaaag attaaaggtc tgacagttgg aaacttctat
     8161 acagtttatt tctttattcg agagttagct ggtttctttt caattcgtct aggaggacac
     8221 cctcagtttg tcagaccttt ggttcaacct atgggagaag cagctgcaga gtctcaatta
     8281 ggtagaaagt taacagaggt tgaagatgag acaataaaag cgcgtgcggc tgcgaatgaa
     8341 aattttggaa atttctttgc tcaaaatacg tttgtaggtg ctgggggagt cctcttgata
     8401 gggggaacat tagatcagtt aggctatgaa agcaattatg cagggattgc ttctacatct
     8461 attattgttg ctgttataac acttattgta gtggggattt acaattattt atttgataaa
     8521 aaattgatat caaaaaagac taggggagga gaacaaaaat gacagagttg gcaaagcaac
     8581 tattagagtt gacctatatt gtgattggtt gtcaatttct ccatacagcc tattgtagtt
     8641 ataaagataa aacaaaccca gttcgacttg ggacatctgc attttggact ctattgtcta
     8701 ttacgtttat aggtggttcc tatatgccaa atatgagtat tggtattatt gtaatcctat
     8761 tatcgctgtt aacattgttt aagcaagtcc gtatcggaac cttgccatcc ttagatgaaa
     8821 tgaaagccaa tattgaatct aacaggttga aaaataaaat ttttattcca gttatgctga
     8881 tggcaatact tgcgttggtc ttagcgcaaa tgattccaga atttagcaag atttcgatta
     8941 gccttgccgc cttgtttgct acaatttctg ttcttgtgat taccaatagt caccctaaga
     9001 gtctgttatc agaaaataat cgaatgactc agcaagtttc aacaagtggg attgttcctc
     9061 aattattagg ggctttgggg gctattttta ctgtagcagg tgttggtgat gttatctctc
     9121 atctgattag cggtattgtt ccttcagata gtcgctttat aggagttttg gcttatgttc
     9181 ttggaatggt tctattcaca atgattatgg gaaatgcttt tgcagcattc accgttatta
     9241 cagcaggtgt tggagttccc tttgtatttg ctctgggagc taatccaatt gtggctggtg
     9301 ctcttgccat gacagcaggt tattgtggga ccttattgac cccaatggct gctaatttta
     9361 acgctctacc agcagcattg atggatatga aagatcagaa tggcgttata aaggctcaag
     9421 caggtgttgc tctagtaatg attgttattc acatattctt aatgtacttt ctcgcatttt
     9481 agtaaaggaa aataaaatga aaatattggt tacaggtttt aatccttttg gaggtgaaaa
     9541 gattaatcca gctttggagg ctgtaaaatt attaccatct gagattaatg gggctgaagt
     9601 tcgctgggta gaaattccaa cggtttttta taagtcgtca gaagttttag aggcagaaat
     9661 attacgatat caaccagatg ctgtactttg tattggacaa gcaggcggca ggaccggctt
     9721 aacacctgaa cgagtggcta ttaatcaaga tgatgctcgc atacctgata acgaaggcaa
     9781 tcaaccaatt gatacaccga ttcgtattga tggagcatcg gcctatttta gtagtttacc
     9841 tatcaaagcg atggtacaag ctatcaaaaa acagggactt ccggcagttg tatccaatag
     9901 tgcaggaacc tttgtttgca atcatttgat gtaccaagct ctttatttag tggataaaaa
     9961 attccctaat atgagagcag gtttcatgca tattccatat atgatggaac aagtagtaaa
    10021 taagccgaat actgcaggaa tgagtctatg tgatattgta agaggcatag aggtagctat
    10081 tgaagctatt gtagactaca aagataagga tttgcagtta gtaggcggtg agactcactg
    10141 ataacctaaa aaggatagtc aattatgctt gtttactaac tattaactat gctaaatcaa
    10201 ttgaggttgt ttacataaaa
//
LOCUS       DAVLXH010000064        10174 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00028199
            SAMN33607166-rid17955573.denovo.064, whole genome shotgun sequence.
ACCESSION   DAVLXH010000064 DAVLXH010000000
VERSION     DAVLXH010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607166
            Sequence Read Archive: SRR23725544
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10174)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10174)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721421.1
            Genome Coverage       :: 115x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:42:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,210
            CDSs (total)                      :: 2,161
            Genes (coding)                    :: 2,023
            CDSs (with protein)               :: 2,023
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 73 of 138
            Pseudo Genes (incomplete)         :: 60 of 138
            Pseudo Genes (internal stop)      :: 40 of 138
            Pseudo Genes (multiple problems)  :: 31 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10174
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607166-rid17955573.denovo.064"
                     /strain="AUSMDU00028199"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1349"
     gene            89..1264
                     /gene="mutY"
                     /locus_tag="VYO11_001857"
     CDS             89..1264
                     /gene="mutY"
                     /locus_tag="VYO11_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HEV1596365.1"
                     /translation="MLDLKEYGIVMWPEEKVISFREKLLAWYDENKRDLPWRRSKNPY
                     HIWVSEIMLQQTRVDTVIPYYERFLDWFPTVESLATAPEESLLKAWEGLGYYSRVRNM
                     QAAAQQIMTDFGGQFPNTYEGISSLKGIGPYTAGAISSIAFNLPEPAVDGNVMRVLAR
                     LFEVNHDIGIPSNRKIFQAMMEILINPDRPGDFNQALMDLGSDIESPVNPRPEESPVK
                     DFSAAYQNGTMDRYPIKSPKKKPVPIYLKALVVKNSQGQFLLEKNESEKLLAGFWHFP
                     FIEVDNFSQEEQFDLFHQVAEESVNFGPSPEESFQQDYDLDVDWLDVCFDTVQHVFSH
                     RKWHVQIVAGQVSDFHDFSDREVRWLSPEEFKNYPLAKPQQKIWQAYAQANLDSSQD"
     gene            1319..2023
                     /locus_tag="VYO11_001858"
     CDS             1319..2023
                     /locus_tag="VYO11_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000722069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1596366.1"
                     /translation="MKKILIVDDEKPISDIIKFNMTKEGYEVVTAFNGREALEQFEAE
                     QPDIIILDLMLPEIDGLEVAKTIRKTSSVPILMLSAKDSEFDKVIGLELGADDYVTKP
                     FSNRELQARVKALLRRSQPMPVDGQEADSKPQPIQIGDLEIVPDAYVAKKYGEELDLT
                     HREFELLYHLASHTGQVITREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPE
                     YILTRRGVGYYMRNNA"
     gene            2016..3365
                     /gene="vicK"
                     /locus_tag="VYO11_001859"
     CDS             2016..3365
                     /gene="vicK"
                     /locus_tag="VYO11_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     VicK"
                     /protein_id="HEV1596367.1"
                     /translation="MLDLLKQTIFTRDFIFILILLGFILVVTLLLLENRRDNIQLKQI
                     NQKVKDLIAGDYSKVLDMQGGSEITNITNNLNDLSEVIRLTQENLEQESKRLNSILFY
                     MTDGVLATNRRGQIIMINDTAKKQLGLVKEDVLNRSILELLKIEENYELRDLITQSPE
                     LLLDSQDINGEYLNLRVRFALIRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSH
                     ELRTPLTSVKSYLEALDEGALCETVAPDFIKVSLDETNRMMRMVTDLLHLSRIDNATS
                     HLDVELINFTAFITFILNRFDKMKGQEKEKKYELVRDYPINSIWMEIDTDKMTQVVDN
                     ILNNAIKYSPDGGKITVRMKTTEDQMILSISDHGLGIPKQDLPRIFDRFYRVDRARSR
                     AQGGTGLGLSIAKEIIKQHKGFIWAKSEYGKGSTFTIVLPYDKDAVKEEVWEDEVED"
     gene            3367..4176
                     /locus_tag="VYO11_001860"
     CDS             3367..4176
                     /locus_tag="VYO11_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEV1596368.1"
                     /translation="MSEIGFKYSILASGSSGNSFYLETSKKKLLVDAGLSGKKITSLL
                     AEINRKPEDLDAILITHEHSDHIHGVGVLARKYGMDLYANEKTWQAMENSKYLGKVDS
                     SQKHIFEMGKTKTFGDIDIESFGVSHDAVAPQFYRFMKDDKSFVLLTDTGYVSDRMAG
                     IVENADGYLIEANHDVEILRSGSYAWRLKQRILSDLGHLSNEDGAEAMIRTLGNRTKK
                     IYLGHLSKENNIKELAHMTMVNQLAQADLGVGVDFKVYDTSPDTATPLTEI"
     gene            4267..4509
                     /locus_tag="VYO11_001861"
     CDS             4267..4509
                     /locus_tag="VYO11_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HEV1596369.1"
                     /translation="MTTITLKVSEADKTFMKAMAKFEGVSLSELIRTKTLEALEDEYD
                     ARVADLAYQEYLEDLEKGVEPITWEEMMHDLGLKDE"
     gene            4511..4765
                     /locus_tag="VYO11_001862"
     CDS             4511..4765
                     /locus_tag="VYO11_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HEV1596370.1"
                     /translation="MYKLVPTRRFIKQLKKLDRYTQKLITNYLQTNVLEDPRRHGKAL
                     VGNRVGQWRYRIGNYRVIVQIVDDELVVATLEVGHRRDIY"
     gene            4812..5585
                     /locus_tag="VYO11_001863"
     CDS             4812..5585
                     /locus_tag="VYO11_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ion transporter"
                     /protein_id="HEV1596371.1"
                     /translation="MKKKWFFADYYDTTIILLALISVILVLLGFAEMIDLDNPPYSII
                     DLVIWGVFVIDYSWRFFTTKRKWRFILENIFDLLAILPLNAIFTVFRLGRIFRLAKLT
                     KLLKLTRLLRIIGLTGKLERKISRFLRTNGLIYILYVNIFIVLVGSSILSVVEEKSFS
                     DSLWWALVTVTTVGYGDIVPASIFGKWLAVLLMLVGIGTIGMLTSALTNFFVKDNPDE
                     QIKLDKLQDELSSQRILLEKQSKKIEELHKMIQDLIEKT"
     gene            complement(5848..6834)
                     /locus_tag="VYO11_001864"
     CDS             complement(5848..6834)
                     /locus_tag="VYO11_001864"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019768616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HEV1596372.1"
                     /translation="MTSTKQHKKVILVGDGAVGSSYAFALVNQGIAQELGIIEIPQLH
                     EKAVGDALDLSHALAFTSPKKIYAAQYSDCADADLVVITAGAPQKPGETRLDLVGKNL
                     AINKSIVTQVVESGFKGIFLVAANPVDVLTYSTWKFSGFPKERVIGSGTSLDSARFRQ
                     ALAEKLDVDARSVHAYIMGEHGDSEFAVWSHANIAGVNLEEFLKDTQNVQEAELIELF
                     EGVRDAAYTIINKKGATYYGIAVALARITKAILDDENAVLPLSVFQEGQYGVENVFIG
                     QPAVVGAHGIVRPVNIPLNDAETQKMQASAKELQAIIDEAWKNPEFQEASKN"
     gene            7028..9496
                     /gene="gyrA"
                     /locus_tag="VYO11_001865"
     CDS             7028..9496
                     /gene="gyrA"
                     /locus_tag="VYO11_001865"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001152996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HEV1596373.1"
                     /translation="MQDKNLVNVNLTKEMKASFIDYAMSVIVARALPDVRDGLKPVHR
                     RILYGMNELGVTPDKPHKKSARITGDVMGKYHPHGDSSIYEAMVRMAQWWSYRYMLVD
                     GHGNFGSMDGDSAAAQRYTEARMSKIALEMLRDINKNTVDFVDNYDANEREPLVLPAR
                     FPNLLVNGATGIAVGMATNIPPHNLGETIDAVKLVMDNPEVTTKDLMEVLPGPDFPTG
                     ALVMGKSGIHKAYETGKGSIVLRSRTEIETTKTGRERIVVTEFPYMVNKTKVHEHIVR
                     LVQEKRIEGITAVRDESNREGVRFVIEVKRDASANVILNNLFKMTQMQTNFGFNMLAI
                     QNGIPKILSLRQILDAYIEHQKEVVVRRTRFDKEKAEARAHILEGLLIALDHIDEVIR
                     IIRASETDAEAQAELMSKFKLSERQSQAILDMRLRRLTGLERDKIQSEYDDLLALIAD
                     LADILAKPERVSQIIKDELDEVKRKFSDKRRTELMIGQVLSLEDEDLIEESDVLITLS
                     NRGYIKRLDQDEFTAQKRGGRGVQGTGVKDDDFVRELVSTSTHDHLLFFTNKGRVYRL
                     KGYEIPEYGRTAKGLPVVNLLKLDEDESIQTVINVESDRSDDAYLFFTTRHGIVKRTS
                     VKEFANIRQNGLKALNLKDEDELINVLLAEGDMDIIIGTKFGYAVRFNQSAVRGMSRI
                     ATGVKGVNLREGDTVVGASLITDQDEVLIITEKGYGKRTVATEYPTKGRGGKGMQTAK
                     ITEKNGLLAGLMTVQGDEDLMIITDTGVMIRTNLANISQTGRATMGVKVMRLDQDAQI
                     VTFTTVAVAEKEEVGTENETEGEA"
     gene            9496..>10174
                     /gene="srtA"
                     /locus_tag="VYO11_001866"
     CDS             9496..>10174
                     /gene="srtA"
                     /locus_tag="VYO11_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase SrtA"
                     /protein_id="HEV1596374.1"
                     /translation="MSQKNNKKKNKRKNLLTNILAGFLILLSLALIFNTQIRNIFIVW
                     NTNKYQVSQVSKEKLEENQDTEGNFDFDSVKAISSEAVLTSQWDAQKLPVIGGIAIPE
                     LEMNLPIFKGLDNVNLFYGAGTMKREQVMGEGNYSLASHHIFGVDNANKMLFSPLDNA
                     KNGMKIYLTDKNKVYTYEIREVKRVTPDRVDEVDDRDGVNEITLVTCEDLAATERIIV
                     KGDLKETK"
BASE COUNT         3138 a         1716 c         2293 g         3027 t
ORIGIN      
        1 agtagataga aaagttatat actatctatt gaaaatatta taaatcagat acaaagacag
       61 gtgaaacctt ctgtgttata ctagagatat gttagatttg aaagaatacg gtatcgtcat
      121 gtggccggag gagaaagtca tttctttccg tgagaaactt ctcgcttggt atgatgaaaa
      181 caaaagagat ttgccttgga ggagaagtaa aaatccttat cacatctggg tatctgaaat
      241 catgcttcag cagaccaggg tggatacagt tatcccttac tacgaaagat ttttggactg
      301 gtttccaact gtcgaaagtc tggcaactgc gcctgaggag agtttactga aagcttggga
      361 gggcttgggc tattattctc gagttcgcaa tatgcaggct gcagcccagc agattatgac
      421 tgactttggt ggccaatttc caaataccta tgaaggaatt tccagcttga aagggattgg
      481 accttacaca gcaggagcca tttccagtat tgcttttaac ttgcctgagc cagctgtaga
      541 tggtaatgtc atgcgggtct tggcgcgtct gtttgaagtc aaccacgata ttgggattcc
      601 aagtaatcga aaaatttttc aggcaatgat ggagatcttg attaatccag atcgtccggg
      661 tgattttaat caagccttga tggacttagg gtctgatatt gagtctcctg taaatcccag
      721 acctgaagaa agcccagtca aggactttag tgcggcatat cagaatggaa ccatggaccg
      781 ttatccaatt aaatctccta agaaaaagcc ggttcctatt tatcttaaag ccttagttgt
      841 gaaaaattct caaggacaat ttttacttga aaaaaatgaa agcgaaaagc tcttggcagg
      901 tttttggcat ttccccttta tagaagttga taacttttcg caagaagagc agtttgacct
      961 ctttcatcag gttgcggaag aaagtgtgaa ctttggcccc agtccagaag agagtttcca
     1021 gcaggactat gacctagatg ttgattggct tgatgtttgt tttgatacag tccagcatgt
     1081 ttttagtcat cgaaaatggc atgtacagat tgtagcaggt caggtgagtg acttccatga
     1141 tttttcagat agggaagttc gttggctttc accagaagaa ttcaagaatt acccacttgc
     1201 caaaccccaa caaaaaatct ggcaggctta tgcacaagcc aacttagaca gtagccaaga
     1261 ctagctattg tgtcttctga ctattttttg gtataatagt agagaaaaag gtgaacatat
     1321 gaaaaaaata ctaattgtag atgatgagaa accaatctcg gatattatca agtttaatat
     1381 gaccaaggaa ggttacgaag ttgtaactgc ttttaatggt cgtgaagcgc tagagcaatt
     1441 tgaagcagag caaccagata ttattattct ggatttgatg cttccagaaa ttgatggttt
     1501 agaagttgct aagaccattc gtaagacaag cagtgtgccc attcttatgc tttcagccaa
     1561 agatagtgaa tttgataagg ttatcggttt ggaacttggg gcagatgact atgtaacgaa
     1621 acccttctcc aatcgtgagt tgcaggcgcg tgttaaagct cttctgcgtc gttctcaacc
     1681 tatgccagta gatggtcagg aagcagatag taaacctcaa cctatccaaa ttggggattt
     1741 agaaattgtt ccagacgcct acgtggctaa aaaatatggc gaagaactag acttaaccca
     1801 tcgtgaattt gagcttttgt atcatttagc atcgcataca ggtcaagtca tcacgcgcga
     1861 acacttgctt gagactgtct ggggttatga ctattttggt gatgtccgca cagttgatgt
     1921 gactgtacga cgtctgcgtg agaagattga agatacgccc agccgaccag agtatatctt
     1981 gacgcgccgt ggtgtagggt attacatgag aaataatgct tgatttactg aaacaaacca
     2041 tttttaccag agattttatc tttatcctga ttttgttagg tttcatcctt gttgtgaccc
     2101 tcttattact ggaaaataga cgtgataata ttcagttgaa gcaaatcaat caaaaggtta
     2161 aagatttgat tgcaggagat tattccaagg ttcttgatat gcaaggtggg tctgaaatca
     2221 ccaatattac caataatttg aatgacttgt cggaggttat tcgtctcact caggaaaatc
     2281 tagaacaaga gagtaagagg ctaaatagta ttctgtttta tatgacagat ggggttcttg
     2341 cgaccaaccg tcggggtcag attatcatga ttaacgatac agccaagaag caactggggt
     2401 tggttaagga agatgttctg aatagaagca ttttggaatt gctcaagata gaagaaaact
     2461 atgaattgcg tgatttgatt acccaaagtc cagaattgtt gctagattcc caagatatca
     2521 atggcgaata tttgaacctt cgagttcgct ttgccttgat acgtcgagag tctggcttta
     2581 tttcaggttt ggtggctgtt ttgcatgata cgacggagca ggagaaggaa gaacgcgaac
     2641 gaagactctt tgtttccaat gttagccatg agttacggac tcctctgact agcgtaaaat
     2701 cctatcttga agccttggat gagggggctt tgtgtgaaac tgtagcacca gactttatca
     2761 aggtttctct tgatgaaacc aaccgtatga tgcgcatggt gacggatctc ctccatcttt
     2821 cacgtattga taatgctacc agtcatctag atgtggaact gattaacttc actgctttta
     2881 ttacctttat cctcaatcgt tttgacaaga tgaaaggaca ggaaaaggag aaaaaatatg
     2941 agttggtgag agattatccc atcaattcta tctggatgga aattgataca gataagatga
     3001 cgcaggttgt cgacaatatt ttaaataatg ctattaagta ttcgccagat gggggtaaaa
     3061 tcactgtcag aatgaagaca actgaagacc agatgatttt atccatttct gaccacggtt
     3121 tggggattcc taagcaggat ttaccacgta tctttgaccg tttttatcgt gtggatcgtg
     3181 ctagaagtcg tgcacaaggt ggtacaggtc taggactgtc tatcgctaaa gaaattatca
     3241 aacaacataa gggctttatt tgggccaaga gtgaatacgg caagggttca acctttacca
     3301 ttgtgctccc ttatgataag gatgcagtga aagaagaagt atgggaggat gaagtagaag
     3361 actagaatga gtgaaatagg ctttaaatac agtattttag cgtcgggttc cagtggaaat
     3421 tctttttatc tggaaacctc aaaaaagaag cttttagtag atgcaggctt gtctggcaag
     3481 aaaattacca gtctgctagc tgaaattaac cgtaagccag aagacctgga tgccatcttg
     3541 attacccatg agcattcaga tcatatccat ggagtaggcg ttttggctcg caagtatggt
     3601 atggatcttt atgccaatga aaagacctgg caagctatgg aaaatagtaa atatcttggt
     3661 aaggtggatt cttcgcaaaa gcatattttt gaaatgggta aaaccaaaac ctttggagat
     3721 atcgacatcg agagttttgg tgtaagccat gatgcagtcg caccgcagtt ctatcgcttt
     3781 atgaaggatg ataagagttt tgtccttttg acagatacag gttatgtcag tgaccgtatg
     3841 gcgggcattg tcgaaaatgc ggatggctat cttatcgagg ccaaccatga tgtagagatt
     3901 ttgcgatcag gttcttacgc ttggcgactc aaacaacgaa tcctatctga ccttggtcac
     3961 ctttctaacg aggacggtgc tgaagctatg attcggacgc taggaaatcg tactaagaag
     4021 atttaccttg ggcatttatc taaggaaaat aatatcaagg aactggctca tatgaccatg
     4081 gtcaatcagc tggctcaagc tgatctggga gtcggagtag actttaaggt ttatgatacc
     4141 tcaccagata ccgcaacacc attgacagag atataaaaag aacgctgaga aggtgttctt
     4201 tttatattga ctgaacacct aaaaagtaat acaatggtgt taccattaaa aaagggagca
     4261 caaaagatga ctactattac attaaaagtt tctgaagctg ataaaacatt tatgaaagca
     4321 atggctaagt ttgaaggagt ttccctttcg gaacttattc gcaccaaaac tcttgaagcc
     4381 ctagaagatg aatacgatgc tcgtgtggca gatttagcct atcaagagta tttagaagac
     4441 ttggaaaaag gagttgaacc cattacttgg gaagaaatga tgcatgattt aggcttgaag
     4501 gatgaataat ttgtataaat tagttccaac aagacgtttt atcaagcaat tgaaaaaatt
     4561 ggaccgttat acgcagaagc taattacaaa ctatttacaa accaatgttt tggaagatcc
     4621 aagacgacac ggaaaggctt tggttggtaa tcgcgttggt caatggcgct atagaattgg
     4681 taattatcga gttatcgtac aaattgtaga tgatgaatta gttgttgcta ctctagaagt
     4741 tggtcatcgg agagatattt attaaattaa agctgagtaa taacagtata gaaagtaagg
     4801 agagtaaaaa tttgaagaaa aaatggtttt ttgcagatta ttatgacaca acaattattt
     4861 tacttgcttt aatctctgtt attctggtat tacttggatt tgctgagatg attgatttgg
     4921 acaatccgcc ttatagtatt attgatttag taatctgggg tgtttttgta attgattata
     4981 gttggcgctt ttttacgact aaaagaaaat ggcgctttat tcttgaaaat atttttgatt
     5041 tattggctat tctcccttta aatgctattt ttacagtgtt tcgattaggg cgtatctttc
     5101 gtttagctaa actaacaaaa ttactgaaac tgactcgttt acttagaata attggactta
     5161 caggtaaatt agaaagaaaa attagtagat tcttacggac aaatggcctg atttatatct
     5221 tgtatgttaa tatctttatt gttctagtag ggagttcgat tttatccgtt gttgaagaaa
     5281 aatccttctc agatagtctt tggtgggctc ttgtgacagt aactactgtt ggatatgggg
     5341 atattgttcc tgcttccatt tttgggaaat ggctagcagt tttactgatg cttgtcggta
     5401 ttggaacaat agggatgtta acaagtgctt tgacgaactt ttttgtaaag gataatccag
     5461 atgaacagat aaaacttgat aaactccaag atgaattatc tagtcagaga atattactag
     5521 agaaacaatc taaaaagata gaagaactac ataaaatgat acaagatttg attgaaaaaa
     5581 cataataaaa ataaagatga gaaaaagttt gaactgagga gaaattaagt aagttttgac
     5641 acaatagaac gcatattatc aggtataaaa acttgatatt atgcgtttta ttgtgggaag
     5701 atgtataatg gattgaaata agatatgaac aaatcgatta ggaatttaaa gcattttata
     5761 acaacgtttt agagtaacgg ggtactattt catataatac aggaaaaaac aactccctga
     5821 tgattcaagg agttgtctat agttaaatta gtttttagaa gcttcttgga attctggatt
     5881 tttccatgct tcgtcaataa tagcttgcaa ttctttagca gatgcttgca ttttttgagt
     5941 ttctgcatcg ttcaatggaa tgtttactgg acgaacgata ccatgtgcac caacaacagc
     6001 tggttgaccg ataaagacat tctcaactcc gtattgacct tcttggaata ctgaaagtgg
     6061 aagtactgcg ttttcatcgt caaggattgc tttagtgata cgagcaaggg ctactgcgat
     6121 accgtagtat gttgcacctt ttttgttgat gattgtgtag gctgcatcac gaacaccttc
     6181 gaacaattca atcaattcag cttcttgaac attttgagtg tctttaagga attcttcaag
     6241 gtttacacca gcgatgttag cgtgtgacca aacagcgaac tcagagtcac cgtgttcacc
     6301 catgatgtag gcgtgcactg aacgagcatc cacatccaat ttttcagcaa gtgcttgacg
     6361 gaaacgagct gagtcaagtg aagtacctga accgataacg cgttctttag ggaaaccaga
     6421 gaatttccaa gttgagtaag tcaaaacgtc aactgggtta gcagcaacaa ggaagatacc
     6481 tttgaaacca gattcaacaa cttgagttac gattgatttg ttgatagcaa ggtttttacc
     6541 tacaaggtca agacgagttt cacctggttt ttgaggtgca cctgcagtga tcacaacaag
     6601 gtcagcgtct gcacagtcag agtattgagc tgcatagatt tttttaggtg aagtgaaggc
     6661 aagggcgtga ctaaggtcaa gcgcatcacc aacagctttt tcatgcaatt gtggaatttc
     6721 gataattcca agctcttgtg caattccttg gttaacaagt gcaaaagcgt aagatgaacc
     6781 tacagcacca tcaccgacaa ggataacttt tttgtgttgt ttagttgaag tcattgtttt
     6841 aaacatctcc ttaattttat taggggattt tccctagaca acttcattct atcactttta
     6901 aaaaactttg tcacgaatat gccttatagt tctcgatgta aacgttttag tggtttagag
     6961 gctgaaatag atgggaattt atggtataat gttgttactt actaattgtg aaatgaggca
     7021 tttattaatg caggataaaa atttagtgaa tgtcaatctg acaaaggaga tgaaggcaag
     7081 ttttatcgac tacgccatga gtgttatcgt agcgcgagct cttcctgatg ttcgagatgg
     7141 cttaaaacct gttcaccgtc gcattctcta cggaatgaat gaattgggtg tgaccccaga
     7201 caaaccccat aaaaaatctg ctcgtattac aggggatgtc atgggtaaat atcacccaca
     7261 cggggattcc tctatttatg aagctatggt ccgtatggct caatggtgga gctaccgtta
     7321 catgcttgta gatggtcatg ggaattttgg ttccatggat ggagatagtg ctgccgctca
     7381 acgttatacc gaggcacgta tgagcaagat tgctctggaa atgcttcgtg atatcaacaa
     7441 aaatacagtt gatttcgttg ataactatga tgccaatgaa cgggaaccct tggtcttgcc
     7501 agcgcgtttt ccaaaccttt tggttaatgg agcaactggt atcgcggttg ggatggcaac
     7561 caatattcca cctcataatc tgggtgaaac cattgatgca gtgaagttgg tcatggataa
     7621 tcctgaagtg actaccaagg acttgatgga agtcttgcct ggaccagatt ttccaactgg
     7681 tgctcttgtc atggggaaat caggtatcca taaggcttat gaaacaggta aaggttcgat
     7741 tgtcctacgt tctcgtacag agattgaaac gactaagact ggtcgtgagc gtatcgttgt
     7801 aacagaattt ccttacatgg tcaataaaac caaggtgcat gagcatattg ttcgcttggt
     7861 tcaggaaaaa cgcattgagg gtatcacagc agtacgtgat gagtcaaacc gtgaaggtgt
     7921 tcgatttgtt attgaagtca agcgcgacgc ctcagccaat gttattctca ataacctctt
     7981 caaaatgacc caaatgcaaa ccaattttgg tttcaatatg ctcgctatcc aaaatggtat
     8041 accgaaaatt ttgtctcttc gtcagatttt ggatgcttat atcgagcacc aaaaagaagt
     8101 ggttgttcgt cgtacacgtt ttgataagga aaaagcggaa gcgcgcgctc atatcttaga
     8161 aggtctcttg attgcgctag accatatcga cgaagtgatt cgtatcatcc gtgctagtga
     8221 aacggatgcg gaagctcaag ctgagttgat gagcaagttt aagctttctg aacgtcaaag
     8281 tcaagctatc cttgatatgc gtcttcgtcg tttgacaggt ttggaacgcg ataagattca
     8341 atctgagtat gatgacctct tggctctgat tgcggattta gcagatattc ttgctaagcc
     8401 tgaacgtgtt tctcaaatta tcaaagacga attggatgaa gttaaacgta aattttctga
     8461 taagcgccgt acagagttga tgattggaca ggtcttgagt ctcgaggatg aggacttgat
     8521 tgaagaatcg gatgtcttga ttaccctttc taacagaggc tacattaagc gtttggatca
     8581 ggacgagttc actgctcaaa aacgtggggg tcgtggtgtc caaggaacgg gagtgaaaga
     8641 tgatgacttt gttcgtgagt tagtgtcaac tagcacccat gatcatctgc tcttcttcac
     8701 aaacaaggga cgtgtctatc gtcttaaagg ttatgaaatt cctgagtatg gtcggactgc
     8761 caaagggcta ccagtagtca atctcttgaa attggatgaa gacgaaagta ttcagacggt
     8821 tatcaatgtt gagtctgatc gcagtgatga tgcttatctc ttctttacaa cccgtcacgg
     8881 tattgtgaag agaactagtg ttaaggagtt tgccaatatt cgtcaaaatg gtctcaaagc
     8941 gctgaattta aaggatgaag atgagttaat caatgtcttg ttggcagaag gagatatgga
     9001 tattatcatt ggtaccaagt ttggttatgc agttcgcttt aatcaatcag ccgttcgtgg
     9061 tatgagccgt atcgccactg gtgtgaaagg ggttaacctt cgtgaaggag acacagttgt
     9121 tggtgccagc ttgattactg atcaagatga ggttcttatt atcacagaaa aaggatatgg
     9181 taagcgtaca gtcgctactg aatacccaac aaaaggtcgt ggtggtaagg gaatgcagac
     9241 agctaaaatt accgaaaaaa atggcttgct ggccggtctt atgactgttc aaggggatga
     9301 ggatttgatg attatcactg atacaggtgt catgattcga accaatcttg ccaatatttc
     9361 acaaacagga cgtgcaacta tgggagttaa agtaatgcgc ctggatcaag atgctcagat
     9421 agtgactttc acaacggttg cggtggcaga aaaagaagaa gttgggacag aaaacgaaac
     9481 agaaggtgaa gcataatgtc tcaaaaaaat aataaaaaga aaaacaagcg aaaaaatctg
     9541 ctgacaaata tcctagcagg atttctgata ttactgtcac tggctttgat ttttaatact
     9601 caaattcgaa atattttcat agtctggaat accaataagt atcaagttag ccaggtatca
     9661 aaagaaaaat tagaagaaaa tcaggataca gaaggcaatt ttgactttga ttctgtcaaa
     9721 gctatctctt cggaagctgt tctaacttct caatgggatg ctcaaaaatt accagttatt
     9781 gggggaattg caattcctga attggaaatg aatttgccga tttttaaagg acttgataat
     9841 gttaatctct tctacggagc tggtacaatg aaacgcgagc aagtaatggg agaaggaaat
     9901 tatagtctag ctagtcacca tatctttggt gttgataatg ctaataaaat gttattttct
     9961 cctttagata atgctaaaaa tggcatgaag atttatctaa ccgataaaaa taaagtttat
    10021 acttatgaaa tacgtgaagt caaacgtgtg acaccggatc gtgttgatga agttgatgat
    10081 agagatgggg tcaatgaaat cacattagta acctgtgaag accttgctgc tacagaacgt
    10141 attattgtca aaggtgattt gaaagaaaca aaag
//
LOCUS       DAVLXH010000065        10080 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00028199
            SAMN33607166-rid17955573.denovo.065, whole genome shotgun sequence.
ACCESSION   DAVLXH010000065 DAVLXH010000000
VERSION     DAVLXH010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607166
            Sequence Read Archive: SRR23725544
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10080)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10080)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721421.1
            Genome Coverage       :: 115x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:42:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,210
            CDSs (total)                      :: 2,161
            Genes (coding)                    :: 2,023
            CDSs (with protein)               :: 2,023
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 73 of 138
            Pseudo Genes (incomplete)         :: 60 of 138
            Pseudo Genes (internal stop)      :: 40 of 138
            Pseudo Genes (multiple problems)  :: 31 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10080
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607166-rid17955573.denovo.065"
                     /strain="AUSMDU00028199"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1349"
     gene            28..341
                     /locus_tag="VYO11_001867"
                     /pseudo
     CDS             28..341
                     /locus_tag="VYO11_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829800.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            1025..1186
                     /locus_tag="VYO11_001868"
     CDS             1025..1186
                     /locus_tag="VYO11_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005761276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1596375.1"
                     /translation="MDNDWNGLADLIANLIAKYAGALDLDNLPDPTPAKNQEMKNSFD
                     MAKTQIETD"
     gene            1278..2962
                     /locus_tag="VYO11_001869"
                     /pseudo
     CDS             1278..2962
                     /locus_tag="VYO11_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031864.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
     gene            3230..3796
                     /locus_tag="VYO11_001870"
     CDS             3230..3796
                     /locus_tag="VYO11_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1596376.1"
                     /translation="MVILELYQNDYSKDLVAFDSIEDGKAFVAQIPGYTLETEDGFEV
                     EYFNPKNIPDYMEIIFNGNIVPLSKFMFDPEENVNIIWKEISNLSLKNDRVIEGYSKI
                     DAYVVNNHEVKAYVETRETNYRKAKDFLESRGYEIDRSFFGSEDGEAILYRKKGIEVW
                     HFLCHLDPMFVEIEDVEGYVKEEVGEIQ"
     gene            4118..4306
                     /locus_tag="VYO11_001871"
     CDS             4118..4306
                     /locus_tag="VYO11_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopG family transcriptional regulator"
                     /protein_id="HEV1596377.1"
                     /translation="MATDKNRIMISLDDKNLEKLENLVEDARDRRGMRLTKSQVIELL
                     LNTVDYFDDIMGAIYSKK"
     gene            4368..5126
                     /locus_tag="VYO11_001872"
     CDS             4368..5126
                     /locus_tag="VYO11_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HEV1596378.1"
                     /translation="MVVYIRQSKLPSEVSINKYNAQVGAYLQGEEAVLYQSFSEIKEL
                     TSEDIVVDYIMETRALLKMMGLNVPVHDYPIELKEFYGRKIYAGILGEIVNIPDNWGK
                     FIKPKAGSKVFTGRVVNGTHDLIGIGLPFDYPIWISEVVEFIAEWRCFVLDGRVLDVR
                     PYTGDYHAQFDASVIDEAISCWKDAPIAYGLDIGVTRDGRTLVVEVNDGYALGNYGLS
                     PLKSINFHRARWKEMVKPYFEKNEIFKIQQDVVF"
     gene            5184..5645
                     /locus_tag="VYO11_001873"
     CDS             5184..5645
                     /locus_tag="VYO11_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000901908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="HEV1596379.1"
                     /translation="MLGAIIGDIVGSVYEWNNIKTKDFPLFRKDCFFTDDTVMTCAVA
                     EAIMNGGQKDDFIDAMKKYGRMYPNADYGARFNAWLNSDNREPYNSFGNGSAMRISPC
                     AWIMDCGFYAKTGIWPSSRGLTSLSAEVTHNHPEGVKGAMATADAIFLCRF"
     gene            5679..6038
                     /locus_tag="VYO11_001874"
     CDS             5679..6038
                     /locus_tag="VYO11_001874"
                     /inference="COORDINATES: protein motif:HMM:NF015692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="HEV1596380.1"
                     /translation="MNDNPIECKRRIKDYIEKEYDYNLSQTLDEIRPNYRFNETCQET
                     VPQAIIAFLESRDFEDAIRNAISLGGDSDTLAAITCSIAEAAYGIPDWIKDKAYSYLD
                     EPLKDVVRRWENRIKVY"
     gene            6150..7034
                     /locus_tag="VYO11_001875"
     CDS             6150..7034
                     /locus_tag="VYO11_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HEV1596381.1"
                     /translation="MKKAMVIINPTSGGEKALDYKEKLENKAKEYFEYVETKITEKAL
                     DATHFAEEASREQYDAVVVFGGDGTVNEVISGIDERDYIPKLGIIPGGTGNLITKLLE
                     INQDIDGAIDELDFDLTNKIDIGKANDNYFGYIFSIGSLPEAIHNVEIEDKTKQGILA
                     YAVNTMKSVMTDQVFNIKVETENGNYVGEASHVLVLLTNYFADKKIFEENKDGYANIL
                     ILKDASIFSKLSVIPDLLKGDVIANDNIEYIKARNIKISSDSELESDVDGDKSDNLPV
                     EIKVLAQRVEVFSKPKED"
     gene            7197..8936
                     /locus_tag="VYO11_001876"
     CDS             7197..8936
                     /locus_tag="VYO11_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glycosidase"
                     /protein_id="HEV1596382.1"
                     /translation="MELSAIYHRTESEYAYLYKDKKLHIRIRTKKGDIESINLHYGDP
                     FIFMEEFYQDTKEMVKITSGTLFDHWQVEVSVDFARIQYLFELRDTEGQNILYGDKGC
                     VENSLENLHAIGNGFKLPYLHEIDACKVPDWVSNTVWYQIFPERFANGNALLNPEGTL
                     DWDSSVTPKSDDFFGGDLQGIIDHMDYLQDLGITGLYLCPIFESTSNHKYNTTDYFEI
                     DRHFGDKETFRELVDQAHHRGMKVMLDAVFNHIGSQSLQWKNVVKNGEQSAYKDWFHI
                     QQFPVTTEKLVNKRDLPYHVFGFEDYMPKLNTANPEVKNYLLKVATYWIEEFNIDAWR
                     LDVANEIDHQFWKDFRKAVLAKNPDLYILGEVWHTSQPWLNGDEFHAVMNYPLSDSIK
                     DYFLRGIKKTDQFIDEINGESMYYKQQISEVMFNLLDSHDTERILWTANEDVQLVKSA
                     LAFLFLQKGTPCIYYGTELALTGGPDPDCRRCMPWERVSSDNDMLNFMKRLIKIRKYA
                     SVIISHGKYSLQEIKSDLVALEWKYEGRILKAIFNQSTEDYLLEKEAVALASNCQELE
                     NQLVISPDGFVIF"
     gene            9211..9513
                     /locus_tag="VYO11_001877"
     CDS             9211..9513
                     /locus_tag="VYO11_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1596383.1"
                     /translation="MGAARDFLELINHKGLPLFNPLVGDSHVNNRQEYDNTGSGNLQP
                     EKWNETAKQLYNVIMWLIILWNAKPDTPLFNFKDEVIKYKTYEPFESSIKLVSINE"
     gene            9569..9997
                     /locus_tag="VYO11_001878"
     CDS             9569..9997
                     /locus_tag="VYO11_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1596384.1"
                     /translation="MDGITKDFIKTAKLMKQLWPQLTDKEAIDEVKKYTNGKNTAIFT
                     EVEGDTIVGLALCSLRFDYVEGCKYSPVGFLEGIIVDEEYRLKDIAKNLCTKCEEWAK
                     NKGCKEFASDCTLTNTDSIRFHLNIGFQEANRIIHFKKKL"
BASE COUNT         3607 a         1383 c         2111 g         2979 t
ORIGIN      
        1 taccgataga cagtagaggt actccagatt ggaattacat ggaaagatat agagatagat
       61 aaagagagag ggagagatag ataaaaagtc cacccccatt tttttatgga gaattcaaaa
      121 atgtaaggtt aagcaaagaa gaatataaaa atctaaaaga aaaattaaac tcacacacag
      181 atataatgat aaataaacta tccagataca tggaaagcag tggtaagacc tatcaaaacc
      241 actatgtgac aatcttaaaa tggtatgaag aagataaaga caaactaaga cagaaaggtt
      301 taaataaaaa aatgaattat gatgtaggag aatctttata gataaaaaga ggtggaaagg
      361 cactattaaa gactttaagt ctaaaaaggt atcaaagtat gccagagata aaaaaatata
      421 aatatgacac tttaaaggtg attagaaaat taaagaaatg ctagaagact tttagatgac
      481 agttaccaag agggtctaat tttcactgct acttatgcag tgggaattgg acctttttat
      541 ataagcaaat tctatttcaa aattggttac caagaaagac ttcttttcac tgttaagtat
      601 aagagggtaa tttatagaat tttgttacat taagataaat attttctgat ggtcaaattt
      661 taaaaagatt aataattctc gataaatttt gaaccttaac aattgaatag accaagacaa
      721 gacgttaatt atttttggag cgtaataacc tatccgtcaa gatctttcgg ctgaataatt
      781 cggcaaaaaa agttctgcta agtaaaaaga aagtgagcga taagtaagag tttgaatata
      841 gggagggata ccctatccgc tatgaagaaa atgaggataa tgatacttct aaggttgaag
      901 ccggctcatc cggaatagag gcggaggtga gattcctatg ttgctaatcc aaagcacttg
      961 tcaatgtcaa aaaacttaat taaacaaata attattagat ataaaacttt agaggaggta
     1021 tatattggac aatgactgga atggattggc tgatttaata gcaaatctga ttgcaaaata
     1081 tgctggtgct ttagatttag ataatctacc cgatccaacg ccagcaaaaa atcaagagat
     1141 gaaaaatagt tttgacatgg caaaaacaca aattgagacg gactaataaa agtgttataa
     1201 tatacttgaa atgatagtcc aaacttaaat taaaaaaatt atatatgata tagaaaaatt
     1261 atattgaggt taatactatg tcaaaagaaa aaataaaagt atacctctat acacgagtat
     1321 ctacgtcaat acagatagag gggtattcgt tagaggcaca aaaatcacga atgaaagctt
     1381 ttgctattta caacgattat gaaattgttg gagagtatga agatgccggg aagtctggca
     1441 agtctattga aggtagaata cagttcaatc gaatgatgga agatataaaa tctggaaaag
     1501 atggagtatc ttttgttctt gtgtttaagt tatcaagatt tgcaagaaat gccgctgatg
     1561 ttctttctac acttcagata atgcaggatt atggagttaa tcttatctgc gttgaagatg
     1621 gcattgattc atctaaagat gctgggaaac taatgatttc tgttttatca gctgtggctg
     1681 aaatagaaag agaaaacatc cgtattcaaa caatggaaga ttgcattcaa aaagcaaggg
     1741 aaggaaaatg gaatggtggc tttgctccgt atggatataa acttgaagac ggcaagctgt
     1801 ttataaatga ggaagaggca gttgcaataa gaacgatttt cgaccagtat gtaaatacta
     1861 cgataggagc caatgggata tctaaatact tagagaatca tggaattaga aaaatcccaa
     1921 gacagaatgg taagaatcct ttgtttgatg caggtcttat aagaaagata ttaaagaatc
     1981 ctgtatataa tgggaaaata gcatttggaa gaagaacttt agaaaaagtt catggtacaa
     2041 gaaatgaata taagcaggtt gaacaagatg aatatctaat atctgaaggg atacatgaag
     2101 ctatagtttc cgatgaagtt tggcaagctg ctcaggttaa gctaaaatct caagcaaaga
     2161 aatatgagca tgtgaataaa ggaaaagata cacgcacaca cttgctttct ggaattgtaa
     2221 aatgcccgat atgtggagtg ggaatgtttg ggaacaagtg tatcaagaaa aagaaagatg
     2281 gcacaaagta taaagatttt tattacttta ctatggttgt aaacataggc agatgataag
     2341 aggtcataag tgtacattca gtaagcaaat tagagaagaa ttgttagatg atgctgttgc
     2401 agaggtgatt gtcaagatag taagtaatcc gaaatttgct tctatgatgc aagaaaaaat
     2461 caacatgaag gtggatacct ctgaaataga aaaagaaata gataattacc aaaaggaatt
     2521 gagaaagagt cattctacaa agtttaagct aattgaggaa atagataatt tagatgttga
     2581 agataagcac tataagagaa ggaaacagga tttagatgat agactatatc gtatgtatga
     2641 caaaatagat gaattagaat catcactaat tgatgcgaaa gcaaagaaac agactattga
     2701 agctgaaaaa cttacaggag ataacatata taaggttctg atctattttg ataagctcta
     2761 taaagtcatg aatgatgtag agcgtaggca gttaatttca gctttgattt ctgaaattca
     2821 agtttatgaa gaaaaacaat ctaacggaca atggctaaaa tccattactt ttaagctacc
     2881 aattatagaa gaaaatctca acatagattt ggacaatgat gaacaagttg aatgtgtaag
     2941 tttattagag aaacgtagtt aatcctcaaa aggttcccca aactttttga gtcccactga
     3001 cgcatcacgc tgaggcggta tcactgcttg tacgagttga agcatcagcg aagtaaaagt
     3061 agatgttcag ccaatgcgac gaggtgagac cgaaggtcga taaggtgtgt tctgggtata
     3121 ggactcgtaa agtaagtagg aaatatgatg agatgataca gagagcctga attggtcagg
     3181 tgacgtgctt atttacatta gcctgataat gaaaatggag agattatcga tggttatatt
     3241 ggaattgtac caaaatgatt attctaaaga tttagtagca tttgattcca tagaagatgg
     3301 gaaagccttt gtggctcaaa tcccgggata cactctggaa acagaagatg gttttgaagt
     3361 ggagtatttt aatcctaaaa acataccgga ttatatggaa attattttta acggaaatat
     3421 tgttccttta tctaaattta tgttcgatcc tgaggaaaat gtaaacatta tttggaaaga
     3481 gatttcaaat ttatccctca aaaatgatag agtgatcgaa ggatattcaa aaattgatgc
     3541 atatgtcgtt aacaaccatg aagttaaagc ctatgtcgaa acaagagaaa cgaactatcg
     3601 taaagcaaaa gacttcttag aaagccgcgg atatgaaatc gacagaagct ttttcggaag
     3661 tgaagacggt gaagcgattc tttacagaaa aaaagggatc gaagtttggc atttcttgtg
     3721 tcacttagac ccaatgtttg tagagattga agatgtagaa ggatatgtta aagaagaagt
     3781 tggagagatt caatagtcaa ccaaagttcc ttgtgagtat atacctttgc tagtaaaaga
     3841 gtcaaaacgt tataacgaag ggggggaaga aaacccttga gtgtaagtct ttttcttgtt
     3901 tagagggaaa gtattagagt agccgctcat aatttatact agatttgata actgatttga
     3961 gacagatttt atttctataa atattgtgaa aattttttaa taccaaagat ttaaagttac
     4021 tgtgttaaaa atcctctcca cttttaaact aatgtattat aaaagccagt tgacacaagt
     4081 gttacacctg tgatagaatt aacttgaggt gatgaaaatg gcaaccgata aaaatagaat
     4141 aatgattagc ttggatgata aaaatctaga gaaacttgaa aatttagtag aagatgctag
     4201 agatagaagg ggaatgcgac taacaaagtc ccaggttatt gaattactcc taaataccgt
     4261 tgattatttc gatgatatta tgggggctat ttactcaaaa aaataagagc aaaattgcta
     4321 ttatttttta caaattggtg taacactagt gatataggag tgatgaaatg gttgtttata
     4381 ttagacaaag taaattacca agtgaggttt caattaataa atacaatgct caagtaggtg
     4441 cctacttaca aggagaagaa gctgttttat atcaatcttt ttctgaaata aaagagttaa
     4501 caagtgaaga tatagttgta gattatataa tggagactag agcattacta aaaatgatgg
     4561 gcttaaacgt tccggttcat gactatccta ttgagcttaa agagttttat ggtcgaaaga
     4621 tttatgctgg tattttagga gagattgtga atatacctga taattgggga aaatttatta
     4681 agcctaaagc tggttcaaaa gtctttactg gaagagttgt taatggaacc catgatttaa
     4741 taggtattgg tctacctttc gactatccta tatggattag tgaggttgta gaattcatag
     4801 ctgaatggcg ttgttttgtg ttagatggtc gcgtattaga tgttcgaccc tatacaggtg
     4861 attatcatgc acaatttgat gcaagtgtaa ttgatgaagc gatatcatgt tggaaagatg
     4921 cgccaatagc ttatggacta gatatcggtg ttactcgcga tggcagaaca cttgttgttg
     4981 aagtaaatga tggttatgca ttgggaaatt atggcctatc tcctttaaaa tcaatcaatt
     5041 ttcatagagc taggtggaaa gaaatggtaa aaccctattt tgaaaaaaat gaaattttta
     5101 aaatccaaca ggatgttgtt ttctaaaata aatatggtat ataaccaata taaaaagcat
     5161 caaaatgaac aaggaggaat ctgatgcttg gagcaattat tggagatatt gtcggttctg
     5221 tttacgaatg gaacaatatc aaaacaaagg actttccttt atttcggaag gactgctttt
     5281 ttacagatga cacggttatg acctgtgctg ttgcagaagc aattatgaat ggtggacaaa
     5341 aagacgactt cattgacgcg atgaagaaat atggcagaat gtatccgaat gctgattacg
     5401 gtgctcggtt taatgcatgg ctaaacagcg ataaccgtga gccttataat agctttggga
     5461 atggatcagc tatgcgtatt tctccatgtg cttggatcat ggactgtggt ttttatgcga
     5521 aaactggtat atggccatca tctagaggac ttacgagtct ttctgcagag gtaactcata
     5581 atcatccaga aggtgtcaaa ggcgctatgg ctacagctga tgctatcttt ctatgtcgtt
     5641 tttaatttgg tggttattgt agagagtacg agtaatcaat taacgacaat cctatagagt
     5701 gtaaaagacg aattaaggat tatatagaaa aagaatacga ttacaatcta tctcaaactt
     5761 tagatgaaat ccgtcctaac tatcgtttta acgaaacatg tcaggaaact gtccctcaag
     5821 ccattatcgc ctttcttgaa agtagagact tcgaagatgc gataagaaat gccatctcac
     5881 ttggtggcga cagtgatact ctcgcagcaa tcacttgtag catagcagag gcagcttacg
     5941 gtattcctga ttggatcaag gataaggcct attcttactt ggatgaaccc ttaaaggatg
     6001 tagttaggcg atgggaaaat agaataaaag tgtattaatc tccagtacgt cagatttctc
     6061 ttttctgtat tttcattgta taataggatt acatttactt gcatacgacg aaatgtaaac
     6121 atttctattt aaaattaagg ataaaatcaa tgaaaaaagc aatggtaatt atcaacccta
     6181 cttctggtgg cgagaaggct ttggattaca aagaaaagct ggagaataaa gcaaaagaat
     6241 actttgaata tgttgaaacc aaaattaccg aaaaagcgct ggatgcaaca cattttgctg
     6301 aagaagcttc tcgtgagcag tatgatgcag tggttgtgtt tggtggagat gggactgtca
     6361 atgaagtcat ttcaggtatt gatgagagag actacattcc taagttaggg attatcccag
     6421 gcggtacggg taacctcatt acaaaacttt tggaaatcaa tcaagacatc gatggcgcaa
     6481 ttgacgaact ggattttgat ttaaccaata agattgatat cggtaaagca aatgacaact
     6541 attttggtta tatctttagt atcggttctc tgcctgaggc gattcacaat gttgaaatag
     6601 aggacaaaac aaaacaaggt attttagcct atgctgtaaa tactatgaag tctgtcatga
     6661 cagatcaggt ctttaacatt aaggttgaga cagaaaatgg aaattatgtt ggtgaagcta
     6721 gccatgtttt ggtccttttg acaaattact tcgctgataa gaaaatcttt gaagaaaaca
     6781 aggacggcta tgccaacatt ttgattctga aagatgcctc tatattctcc aaattatccg
     6841 tcattcctga tttattaaaa ggggatgtta tcgcaaatga taatatcgag tatatcaaag
     6901 cgcgtaatat taaaatctct tcagatagtg aattggagtc agatgttgac ggagataaat
     6961 cagataacct acctgtagaa atcaaagtcc tagctcagcg agtagaagta ttttcaaaac
     7021 cgaaagagga ttagtatata gagaaagcct tttttaaggc tttttgtata ctttaaaaga
     7081 tagttccttt aacaacggac attccttgca aatagttcac aaaaatagta tactggattc
     7141 attgagtttg aaaacgtttg cgtaaaattt gaatgaatac tttaggagat aaattgatgg
     7201 aattgagtgc tatttaccat aggactgagt cggagtatgc ctatctttat aaggataaga
     7261 aactccatat tcgaattcga actaagaaag gggacattga aagcatcaac ttgcactatg
     7321 gggacccttt tatctttatg gaggagtttt atcaggatac aaaagaaatg gtcaagataa
     7381 cttctggtac cttatttgac cattggcagg ttgaagtgtc agttgacttt gcacgtatcc
     7441 agtatctttt tgagctcaga gatacagaag gtcaaaatat tttgtatggc gataaagggt
     7501 gtgtggaaaa ttctctagaa aatcttcatg caattgggaa tggatttaag ttgccttatc
     7561 ttcatgagat tgatgcctgc aaggttcctg actgggtttc aaatacggta tggtatcaga
     7621 tatttcctga aagatttgcc aatggcaatg ctctattaaa cccagaaggg actttagact
     7681 gggattcatc tgtcacacct aagagcgatg atttctttgg tggtgattta caggggatta
     7741 ttgatcatat ggattacttg caagacttgg gtattactgg actatatctt tgtcccatct
     7801 ttgaatctac aagcaatcac aagtacaata cgacagatta ctttgaaatt gaccgtcatt
     7861 ttggagacaa ggagaccttt cgggaactgg tggatcaagc gcatcatcgt ggcatgaaag
     7921 tcatgctgga tgcggtattt aatcatattg gttcgcaatc tcttcaatgg aaaaatgtcg
     7981 tcaaaaatgg tgaacagtct gcttataagg attggttcca tattcaacaa ttcccagtga
     8041 caactgaaaa gctagttaat aagagagact taccctatca tgtttttggt ttcgaggact
     8101 atatgcctaa gctaaataca gccaatccag aggtcaagaa ttatctttta aaggttgcga
     8161 cttattggat tgaagagttt aatatcgatg cttggcgttt ggatgtggct aatgagattg
     8221 accatcagtt ctggaaggat tttcgtaagg cagttttagc taaaaatcct gatctttata
     8281 tcctaggaga agtctggcat acatctcagc cttggctaaa tggagatgag ttccatgccg
     8341 tcatgaatta tcctttatct gatagtatca aggactattt cttacgagga attaagaaga
     8401 cagaccagtt catcgatgaa atcaatggag agtctatgta ttacaagcag cagatttcag
     8461 aggtcatgtt taatctcttg gattcacatg atacagagcg aatcctgtgg acggccaatg
     8521 aagatgttca actggttaaa tcagccttag cctttctctt tttacaaaaa ggaacaccgt
     8581 gcatttatta cggaaccgag ctagccttga ctggaggacc agatccagat tgtcgtcgtt
     8641 gtatgccttg ggaacgtgta tcaagtgaca atgatatgct gaactttatg aagaggctga
     8701 ttaagattcg gaaatacgcg tcagtaatca tttcgcatgg caagtatagc cttcaagaaa
     8761 tcaaatctga tctagtagct ctggaatgga aatacgaagg acggatcctc aaagcaatat
     8821 tcaaccaatc aacagaagat tatcttttag agaaagaagc agtagcacta gcaagcaatt
     8881 gccaagaatt ggagaatcag cttgtcatct ctccagatgg atttgtgatt ttctaaaaac
     8941 tagttgatga agattatggt acatttcata tcttatatag tataataagg ctagttacta
     9001 aacttgtaaa ggagaactta aatgaattgt agaggacatg aaacaagaca aagaattgtt
     9061 agagattttg aagtttagcc taaagcacat attaagctgt tagcaaatca acaaaaacat
     9121 agtgatgcag gagcaactat tgaagatgaa tattatgtat ttatcgctga gagtaaaatt
     9181 gatggcaaga aggaagttat tcagtgttgc atgggtgcgg caagggattt tttagaacta
     9241 attaatcaca aagggctacc tctttttaat ccgcttgtag gtgattctca tgtaaataat
     9301 agacaagaat atgacaatac agggagtgga aatttacaac ctgaaaagtg gaatgaaact
     9361 gcaaagcagc tttataatgt tataatgtgg ttgattattt tatggaatgc taagccggat
     9421 acacctttat ttaattttaa agacgaagta attaagtata aaacatatga gccttttgaa
     9481 agcagtataa aattggtatc aatcaatgag taacaaagta tcagcatgat tcgaaacatt
     9541 tacttgtaat ttgcggagga acatcaatat ggatggaata acaaaagatt ttataaaaac
     9601 ggctaaacta atgaaacaat tatggcccca attgaccgat aaagaagcta ttgatgaagt
     9661 aaaaaaatat acgaatggca aaaatactgc aatctttact gaagttgaag gtgacacaat
     9721 tgtaggtcta gcactatgtt cactcagatt tgattatgtt gaaggttgta aatatagtcc
     9781 tgttggattc ttagaaggga ttattgttga cgaggaatat cgtttaaagg atattgctaa
     9841 aaatctctgt acaaaatgtg aggaatgggc gaaaaataaa ggatgtaagg aatttgcaag
     9901 tgactgtact ttaacgaata cggattctat aagatttcat ctcaatattg gatttcagga
     9961 ggcaaataga attattcatt ttaagaaaaa attataattt agaaacgtga ataaacttgt
    10021 ttaaacttta tgtatcttta gaaagtgtgt taacttgaaa gaacaaattt ttttgatggg
//
LOCUS       DAVLXH010000066         9794 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00028199
            SAMN33607166-rid17955573.denovo.067, whole genome shotgun sequence.
ACCESSION   DAVLXH010000066 DAVLXH010000000
VERSION     DAVLXH010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607166
            Sequence Read Archive: SRR23725544
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9794)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9794)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721421.1
            Genome Coverage       :: 115x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:42:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,210
            CDSs (total)                      :: 2,161
            Genes (coding)                    :: 2,023
            CDSs (with protein)               :: 2,023
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 73 of 138
            Pseudo Genes (incomplete)         :: 60 of 138
            Pseudo Genes (internal stop)      :: 40 of 138
            Pseudo Genes (multiple problems)  :: 31 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9794
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607166-rid17955573.denovo.067"
                     /strain="AUSMDU00028199"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1349"
     gene            complement(417..2918)
                     /locus_tag="VYO11_001879"
     CDS             complement(417..2918)
                     /locus_tag="VYO11_001879"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014639013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HEV1596385.1"
                     /translation="MSFYNHKEIEPKWQGYWAEHHTFKTGTDASKPKFYALDMFPYPS
                     GAGLHVGHPEGYTATDILSRYKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTA
                     ENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVE
                     ELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLNDLDELDWSESIKD
                     MQRNWIGKSTGANVTFKVKGTDKEFTVFTTRPDTLFGATFTVLAPEHELVDAITSSEQ
                     AEAVADYKHQASLKSDLVRTDLAKEKTGVWTGAYAINPVNGKEMPIWIADYVLASYGT
                     GAVMAVPAHDQRDWEFAKQFDLPIVEVLEGGNVEEAAYTEDGLHVNSDFLDGLNKEDA
                     IAKIVAYLEEKGCGQEKVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPETELPLV
                     LPVTKDIRPSGTGESPLANLTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPH
                     NTEKLADEDLLKQWLPVDIYVGGAEHAVLHLLYARFWHKFLYDLGVVPTKEPFQKLFN
                     QGMILGTSYRDHRGALVTTDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDV
                     VEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITSKEILAENNGALD
                     KAYNETVKAVTEQIESLKFNTAIAQLMVFVNAANKEDKLYIDYAKGFIQLIAPFAPHL
                     AEELWQTVAETGESISYVAWPTWDESKLVEDEIEIVVQIKGKVRAKLMVAKDLSREEL
                     QEIALADEKVKAEIDGKEIVKVIAVPNKLVNIVVK"
     gene            complement(3373..4461)
                     /locus_tag="VYO11_001880"
     CDS             complement(3373..4461)
                     /locus_tag="VYO11_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol dehydrogenase"
                     /protein_id="HEV1596386.1"
                     /translation="MRIFASPSRYIQGENALFENAKSILDLGNYPILLCDQLVYDIVG
                     KRFEDYLHRYGFHIVLALFNGEASDNEINRVVALAEKENCDSIIGLGGGKTIDSAKAI
                     ADLIEKPVIIAPTIASTDAPVSALSVIYTDEGAFDHYLFYSKNPDLVLVDTKVISQAP
                     KRLLASGIADGLATWVEARAVMQANGKTMLGQQQTLAGVAIAKKCEETLFADGLQAMA
                     ACEAKVVTPALENIVEANTLLSGLGFESGGLAAAHAIHNGFTALTGDIHHLTHGEKVA
                     YGTLVQLLLENRPKEELDKYIEFYKKIGMPTTLKEMHLDQVGYDDLIKVGKQATMEGE
                     TIHQMPFKISPSDVAQAIIAVDAYVNSK"
     gene            complement(4479..5147)
                     /locus_tag="VYO11_001881"
     CDS             complement(4479..5147)
                     /locus_tag="VYO11_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HEV1596387.1"
                     /translation="MEFMLDTLNLDEIKKWSEILPLAGVTSNPTIAKREGSINFFERI
                     KDVRELIGSTPSIHVQVISQDFEGILKDAHEIRRQAGDDIFIKVPVTPAGLRAIKVLK
                     KEGYHITATAIYTVIQGLLAIEAGADYLAPYYNRMENLNIDSNSVIRQLALAIDRQNS
                     PSKILAASFKNVAQVNNALAAGAHAVTAGADVFESAFAMPSIQKAVDDFSDDWFVTQN
                     SRSI"
     gene            complement(5166..7604)
                     /locus_tag="VYO11_001882"
     CDS             complement(5166..7604)
                     /locus_tag="VYO11_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl radical protein"
                     /protein_id="HEV1596388.1"
                     /translation="MVNTEVARTTIKTEYFGSLTERMNKYREDVLNKKPYIDAERAVL
                     ATRAYERYKEQPNVLKRAYMLKEILENMSIYIEEESMIAGNQASSNKDAPIFPEYTLE
                     FVLNELDLFEKRDGDVFYITEETKEQLRSIAPFWENNNLRARAGALLPEEVSVYMETG
                     FFGMEGKMNSGDAHLAVNYQKLLQFGLRGFEERARKAKVALDLTDPASIDKYHFYDSI
                     FIVIDAIKVYAKRFVALAKSLAENANPKRKKELLEIADICSRVPYEPATTFAEAIQSV
                     WFIQCILQIESNGHSLSYGRFDQYMYPYMKADLESGKETEDSIVERLTNLWIKTITIN
                     KVRSQSHTFSSAGSPLYQNVTIGGQTRDKKDAVNPLSYLVLKSVAQTHLPQPNLTVRY
                     HAGLDARFMNECIEVMKLGFGMPAFNNDEIIIPSFIAKGVLEDDAYDYSAIGCVETAV
                     PGKWGYRCTGMSYMNFPKVLLITMNDGIDPASGKRFAPSFGHFKDMKNFSELENAWDK
                     TLRYLTRMSVIVENSIDLSLEREVPDILCSALTDDCIGRGKHLKEGGAVYDYISGLQV
                     GIANLSDSLAAIKKLVFEEERISPSQLWHALETDYAGEEGKVIQEMLIHDAPKYGNDD
                     DYADKLVTAAYDIYVDEIAKYPNTRYGRGPIGGIRYSGTSSISANVGQGRGTLATPDG
                     RNAGTPLAEGCSPSHNMDQHGPTSVLKSVSKLPTDEIVGGVLLNQKVNPQTLAKEEDK
                     LKLIALLRTFFNRLHGYHIQYNVVSRETLIDAQKHPEKHRDLIVRVAGYSAFFNVLSK
                     ATQDDIIGRTEHTL"
     gene            complement(7755..9053)
                     /locus_tag="VYO11_001883"
     CDS             complement(7755..9053)
                     /locus_tag="VYO11_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000041357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEV1596389.1"
                     /translation="MSKMDVQKIIAPMMKFVNMRGIIALKDGMLAILPLTVVGSLFLI
                     MGQLPFEGLNKSIASVFGANWTEPFMQVYSGTFAIMGLISCFSIAYSYAKNSGVEALP
                     AGVLSVSAFFILLRSSYIPKQGEAIGDAISKVWFGGQGIIGAIIIGLVVGSIYTFFIK
                     RKIVIKMPEQVPQAIAKQFEAMIPAFVIFLSSMIVYILAKSLTNGGTFIEMIYSAIQV
                     PLQGLTGSLYGAIGIAFFISFLWWFGVHGQSVVNGVVTALLLSNLDANKAMLASGNLS
                     LENGAHIVTQQFLDSFLILSGSGITFGLVVAMLFAAKSKQYQALGKVAAFPAIFNVNE
                     PVVFGFPIVMNPVMFVPFILVPVLAAVIVYGAIATGFMQPFSGVTLPWSTPAILSGFL
                     VGGWQGVVTQLLVLAMSTMVYFPFFKIQDRLACQNEIKQS"
     gene            complement(9070..9378)
                     /locus_tag="VYO11_001884"
     CDS             complement(9070..9378)
                     /locus_tag="VYO11_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000238716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV1596390.1"
                     /translation="MVKIGLFCAAGFSTGMLVNNMKIAAQSSGVEAEIEAFSQSKLAD
                     YAPNIDVALLGPQVAYTLDKSKEICDKCDVPIAVIPMMDYGMLDGKKVLDLALSLISG
                     "
     gene            complement(9424..9744)
                     /locus_tag="VYO11_001885"
     CDS             complement(9424..9744)
                     /locus_tag="VYO11_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEV1596391.1"
                     /translation="MEIIVPDQIIMGLILYAGDAKQHIYKALDYIKNGTCERCEEEIQ
                     LADAALLEAHNLQTKFLAQEASGTKTEITALFVHSQDHLMTSMTEINLIKEIISLRKE
                     LHKK"
BASE COUNT         3035 a         2076 c         1596 g         3087 t
ORIGIN      
        1 aattgataca cttcagactg tgtccttata atttcatttg gagatattcc aaaaatattg
       61 cttgatttat catttgaaaa actaaagaaa gtaataaaaa ctgcaaagag agtgtctaaa
      121 gtgagtatca aatttaaact ttccttgtcc caaagacaat ttttaaaata atatgcaccc
      181 actattgaca ttactaatac tataactgac actacaataa tagaaatctt aaataataaa
      241 atttcacact tcctgctatc gttcactaat ctattcattc tgacctattc taaaagtaac
      301 tctaaagttc atactctaga gttacttctt tttatttcac aacaatgtta actaatttag
      361 ttggcttcaa tagtccagtg gactattgaa ggtggcagat agagctaata aactcgttat
      421 ttaacgacga tattaacgag tttattcggt accgcaatta ctttcacgat ttccttaccg
      481 tcaatttctg ctttgacttt ttcatcagct aaagcgattt cttgtaattc ttcacgtgat
      541 agatctttag caaccatgag tttggcacga acttttcctt tgatttggac gacaatttca
      601 atttcatctt caaccaattt gctttcgtcc caagttggcc aagctacata agagattgac
      661 tcacctgttt ctgcgactgt ttgccagagt tcttctgcca agtgaggtgc aaatggtgca
      721 atcaattgaa taaagccttt ggcatagtca atataaagct tatcttcctt gttagcagca
      781 ttgacaaaga ccataagttg ggcaatagct gtgttgaatt tgagagactc aatttgctca
      841 gtaacagctt tgactgtttc gttgtaagcc ttgtcaagag caccattgtt ttccgcaagg
      901 atttctttac ttgtaatcaa acggtaaact cggtcaagga acttacggct tccttccaaa
      961 ccttcttctg accaagcaat cgaagcatcg agtggtccca taaacatttc ataaacacga
     1021 agggtatcgg caccgtattg ttccaccaca tcgtctgggt taacaacgtt cttgagcgat
     1081 ttagacatct tggctggcgc ttgctccaac tcttcccctg tttctacatg gaagaaggaa
     1141 ccatcacgtt tttcaacctt gtcggttgtc acaagagcac cacggtggtc acggtagctt
     1201 gttcccaaaa tcatcccttg gttaaagagt ttttggaatg gttccttagt cggaacaaca
     1261 ccgaggtcat agaggaattt atgccagaaa cgagcataaa gcaagtgaag tacagcatgt
     1321 tccgcaccac ccacgtagat atctactggc aaccattgtt tgaggaggtc ctcatcagcc
     1381 aatttctcag tattgtgcgg gtcaatatag cgaaggtagt accagcttga accagcccat
     1441 tgtggcatgg tgttagtttc acgacgacct ttgacaccat cttcacgagt cacttcaagc
     1501 cagtctgtca agttagctag tggactttca ccggtacctg aaggacggat gtccttggtg
     1561 acaggcaaga caagcggcaa ttcagtttca ggaacagctg ttgaagttcc atcttcccaa
     1621 tgaataattg gaattggttc accccagtaa cgttgacggc taaagagcca gtcgcggaga
     1681 cggtaggtaa ccttctcctg accacagcct ttttcttcca agtaagccac aatcttggca
     1741 atagcgtctt ctttgttcaa tccatctagg aagtctgaat tgacatgcag gccatcctct
     1801 gtgtaggcag cttcttcgac atttccacct tcaagtactt cgacgattgg aaggtcaaat
     1861 tgtttggcaa attcccagtc acgttggtcg tgggcaggca cagccataac cgcacctgtt
     1921 ccataactag caagaacata gtccgcaatc cagattggca tttccttacc attgacaggg
     1981 ttgatggcat aagcaccagt ccaaacacca gttttttcct tagcaaggtc tgtacgaacc
     2041 aagtcagact taaggctggc ttggtgttta tagtctgcta cagcttctgc ttgctctgaa
     2101 cttgtgatag cgtctactaa ttcatgttca ggagccaaga cagtgaaagt cgcaccgaaa
     2161 agtgtgtccg gacgagtagt aaagactgta aattccttgt ctgttccttt tactttgaaa
     2221 gttacattgg caccagttga tttaccaatc cagttgcgtt gcatatcctt gatagactct
     2281 gaccaatcta gttcatctaa gtcattgagc aagcgctctg cgtaagccgt gattttgagc
     2341 atccattggc gcattggttt gcggacaact ggatagcctc cacgctcaga agttccgtca
     2401 ggaagcactt cttcattggc aatggcagtt cccaattcct caacccagtt tactggcact
     2461 tcagcttcat aggccaagcc tttttcgtaa agcttggtga aaatccattg agtccacttg
     2521 tagtagtttg gatctgttgt gttgacttca cgatcccagt cataagaaaa tccaagcgca
     2581 ttgatctgac gtttgaagtt ggcaatgttt tccgctgtaa attctgctgg gtcattacca
     2641 gtatccatag cgtattgctc tgcaggcaaa ccaaaagcat cccaacccat tgggtgaagg
     2701 acattgtagc cttgcgcacg tttgtaacga ctgaggatat cggttgcagt ataaccttct
     2761 gggtgtccta cgtgcagacc agctccagac ggataaggga acatatcaag cgcataaaac
     2821 ttaggttttg atgcatctgt tcctgtctta aatgtatgat gttctgccca gtagccctgc
     2881 cacttaggct caatttcttt atgattataa aaactcatgg tctctctcca attttgtgat
     2941 gttactatta taccattttt gagggaattt gaaatgtgtt taaagaaaaa actgtatact
     3001 gtatctcatt aattttgatg actatgaatt gctctatctc ccacttttta tcccattgtt
     3061 atgcagtaaa tcaaggagta agtcaagaag cttatctcgt atagcacaaa atacttattt
     3121 tagaccgaag ataaaactgg aatgctaatt aatgtattca caataaatag ccgactacct
     3181 atgtcgcttt ttgatttatg aagaacgtat agtagactga atctgaaata gtacgaaaca
     3241 attgctaaaa catttataga aattaatttt actttcccaa tcgatttgtt ctcatcctat
     3301 ttcaatcttc tatagaattc aatacaggga tcaataaaag actaccattt ggaaaacagt
     3361 agtccttatt gtttattttg aatttacata ggcatctaca gcgataatag cttgagcaac
     3421 atctgaaggc gaaatcttaa acggcatctg atgaattgtc tcaccctcca tagttgcttg
     3481 tttaccaact tttattaaat catcatatcc aacttgatcc aaatgcattt cttttagagt
     3541 tgttggcata ccaatttttt tgtaaaactc aatatactta tcaagttctt ctttaggtct
     3601 attttccaat aatagttgta ctaaagttcc ataagctact ttttcaccat gtgttaaatg
     3661 atgaatgtca cctgtcaatg cagtaaaacc attatgaatt gcatgcgccg cagctaatcc
     3721 tccactttca aaacctagac cactcaataa agtattagct tcaacaatat tttctaatgc
     3781 tggtgtcacc actttagctt cacaagctgc catagcctgt aaaccatctg caaacagcgt
     3841 ttcttcacat ttcttcgcaa ttgcaactcc agccaatgtt tgctgttgtc ccaacatagt
     3901 ttttccattt gcctgcataa ccgcacgcgc ctcaacccaa gttgctaaac catctgcaat
     3961 accagacgct aataaacgct taggggcttg tgaaataact tttgtatcaa ccaaaactaa
     4021 atctggattt ttagaataaa atagataatg atcaaatgca ccttcatctg tataaataac
     4081 agataaagca gatacaggtg cgtcggtcga tgcaattgtt ggagcaataa taacaggctt
     4141 ttcaatcaaa tctgcaatag cttttgcgct atcaatcgtc tttcccccac caagaccgat
     4201 aatactatca caattttctt tctcagccaa ggcaacaact cgattgattt cattgtcaga
     4261 agcttcacca ttaaatagcg ccagaacaat atggaaacca tacctatgta gataatcttc
     4321 aaatcgtttt ccaacaatat cataaaccaa ctgatcgcat aatagaatcg ggtaatttcc
     4381 caaatccaaa attgatttgg cattttcaaa caaggcattt tccccctgaa tatatctaga
     4441 aggactagca aaaattctca tatgtatttc ctctctatct aaatggaacg actattttga
     4501 gtaacaaacc aatcgtcaga aaaatcatca accgcctttt ggatagatgg catggcgaaa
     4561 gctgattcaa aaacatctgc tcctgctgta acagcatgcg cacctgcagc taaagcatta
     4621 tttacttgtg ctacattttt aaaggatgca gctaaaatct tactaggaga gttctgtcta
     4681 tcaatagcaa gagctaattg acgaatgaca gaatttgaat caatgttcag attttccatt
     4741 ctattataat atggagctag gtaatccgct cctgcttcga tagctaataa tccctgaata
     4801 actgtataaa tagctgttgc agtgatatgg tagccctctt tttttagcac ctttattgca
     4861 cgtaatccag ctggagtaac aggtactttg ataaatatat catctcctgc ttgtcttcga
     4921 atttcatgag catcctttaa gatgccttca aaatcttgag aaatcacctg aacatgaata
     4981 gagggtgtag agccaatcaa ttctcttaca tctttgattc gttcaaaaaa attaatagaa
     5041 ccctctcttt ttgcaatagt gggatttgaa gttaccccag ctagcggcaa aatttcagac
     5101 cactttttaa tctcatctaa atttaatgtg tcaagcataa attccataaa aagaacctct
     5161 ttattttaca aagtatgctc agtacgtcct ataatgtcat cttgggttgc cttagaaaga
     5221 acattgaaga atgcagagta tcctgcaaca cgaacaatta agtctctgtg tttttcagga
     5281 tgtttctgag cgtcaatcag cgtctctctg gaaacaacat tgtattgaat atggtaccca
     5341 tgtaaacgat taaagaatgt tcgtaacaaa gcaattagtt ttaatttatc ttcttctttg
     5401 gctaacgttt gaggatttac tttctgattt aagagaaccc cacctacgat ttcatctgtt
     5461 ggtaattttg aaacagattt taaaacagat gtagggccgt gttgatccat attatgtgat
     5521 ggtgaacaac cctctgctaa cggtgtaccc gcgttgcgtc catctggagt tgctaatgtt
     5581 ccacgtccct gccctacgtt ggctgagata gaagatgttc ctgaataacg aattcctcca
     5641 attggacctc ttccataacg tgtattagga tatttagcaa tttcatcaac ataaatgtca
     5701 taagcagcag taaccaattt gtcagcataa tcatcatcat taccatactt aggtgcatca
     5761 tgaatcaaca tttcttgaat gaccttacct tcttctccgg cataatctgt ttccagtgca
     5821 tgccaaagct gacttgggct tatacgttct tcctcaaaca ccaatttttt aattgcagct
     5881 aatgaatccg acaaatttgc aattccaact tgcaatcctg atatataatc atatactgct
     5941 ccaccttctt taaggtgttt tccacgacca atacaatcat cagtcaatgc tgaacataga
     6001 atatcaggaa cttctcgttc caatgataaa tcaatagaat tttcaacaat aacactcatt
     6061 cgtgtcaaat atcttagtgt tttatcccaa gcattttcta attcagaaaa gttcttcata
     6121 tccttaaaat gaccaaagct tggtgcaaac cgtttacccg aagccggatc aattccatca
     6181 ttcatcgtga taagtagaac cttagggaag ttcatataac tcatacctgt gcaacgatag
     6241 ccccatttcc ccggaactgc cgtttcaaca catccaatgg cactgtaatc ataagcatca
     6301 tcttccaata ctccttttgc aataaaagaa ggaataataa tctcatcatt attaaatgca
     6361 ggcataccaa aaccaagttt catcacttca atacactcat tcatgaaacg agcatctaaa
     6421 cctgcatggt aacgtacagt tagattaggt tgcggtagat gggtttgtgc aactgatttt
     6481 aataccaaat aagataatgg gttaacagca tccttcttat ctcgagtctg tccaccaatt
     6541 gtaacatttt gatataaagg acttcctgct gaagaaaatg tatgtgattg actgcgaacc
     6601 ttattaattg taattgtctt aatccaaaga tttgtcagac gttcaacaat gctatcttct
     6661 gtttctttac cactttctaa atcagccttc atatatggat acatatattg atcaaaacgg
     6721 ccatatgaaa gagagtggcc attagattca atttgtaaaa tacattgaat aaaccaaact
     6781 gattgaatag cttctgcaaa agtagttgcc ggttcatatg ggactctaga gcaaatatct
     6841 gcaatctcaa gtaattcttt cttacgttta ggatttgcat tttcggctaa acttttagca
     6901 agagcaacaa agcgctttgc atatacttta atagcatcga ttacgataaa tatagagtcg
     6961 taaaaatgat atttatcaat acttgctgga tctgttaaat ctagagctac cttcgcttta
     7021 cgagcccgct cttcaaaacc tcttaaacca aattgcaaaa gtttctgata gttaactgct
     7081 aagtgagcat ctccagaatt catcttacct tccataccga agaatcctgt ttccatataa
     7141 acagacactt cttcaggtaa taaggcacca gctctagcac gtaaattatt attttcccaa
     7201 aacggagcaa tacttctaag ttgttctttt gtttcttctg taatatagaa aacatctcca
     7261 tcacgctttt caaaaagatc caactcattg agaacaaatt ctagcgtata ttccggaaaa
     7321 ataggagcat ctttattgga agaagcttga tttcccgcaa tcatagattc ttcttcaata
     7381 tagatagaca tattttccaa aatttctttc agcatatatg cacgttttag gacattaggt
     7441 tgttccttgt atcgttcata ggcgcgtgtt gctagaactg ctctctcagc atcaatataa
     7501 ggttttttat ttaaaacatc ttctcgatat ttgttcatcc tttcagtaag gctgccaaaa
     7561 tattctgtct tgattgttgt tcttgctact tctgtattta ccatcgtaag cacctttctt
     7621 tcgaaaatgt ttttatttct ttcgaaaata taataccgat ttttatagaa attttcaagc
     7681 ttttaactag aaaaatttta actctctaat ttttagcaca aatgtgtgag tttaacagta
     7741 acacacaaat acctctaaga ttgtttgatt tcattttggc aagctaaacg atcttgtatc
     7801 ttaaagaatg gaaagtaaac cattgtagac atcgccaata ctaataactg agtcacaaca
     7861 ccttgccatc cacccaccaa aaatcctgat agaatagctg gtgtactcca aggcaatgtt
     7921 acccctgaga atggttgcat gaaacctgtt gcaatagctc catatactat cacagctgca
     7981 agtacaggaa caagaatgaa aggtacaaac ataactggat tcatgacaat cggaaatcca
     8041 aatacaactg gctcatttac gttaaatatt gctggaaaag ctgcaacttt tcctaaggct
     8101 tggtattgtt ttgattttgc tgcaaaaagc atggcaacta caagaccaaa cgtaatccct
     8161 gaacctgata gaattaaaaa tgaatctaaa aattgttgag taacaatatg tgcaccattt
     8221 tctaatgata gattaccaga ggctaacata gctttattag catcaagatt agataaaagc
     8281 agagctgtca ctactccatt tactaccgat tgcccatgaa caccaaacca ccacaaaaat
     8341 gatataaaga atgcaattcc aatagcacca tacaaagatc cagttaaacc ttgcaacgga
     8401 acttgaatag cagaataaat catttctatg aatgttccgc cattagtcaa tgacttcgct
     8461 aaaatatata caatcataga agataagaaa attacaaatg ctggaatcat tgcttcaaac
     8521 tgtttggcaa tagcttgtgg aacttgttct ggcatcttaa taacaatttt tctctttata
     8581 aagaaggtat aaatacttcc tactaccaaa cctataatga tagcaccgat aattccttgg
     8641 cctccaaacc aaactttact aatagcgtcc ccaatcgcct caccttgttt agggatataa
     8701 gatgatctta gcaaaataaa gaatgcagat acagatagaa ctccagctgg taaagcctct
     8761 actccgctat tcttagcata agaataggca attgaaaaac aagaaattag acccataata
     8821 gcaaaagttc ctgaatatac ttgcataaac ggctctgtcc aattagctcc aaaaacacta
     8881 gcaatgctct tatttaatcc ttcgaacggc aattgtccca taatcaagaa caaactgcca
     8941 actactgtca atggcaaaat tgctaacatc ccatctttta gagctataat gccacgcata
     9001 ttcacaaact tcatcatcgg tgcaatgatt ttctgaacat ccatctttga cataataaat
     9061 ctccttttct tacccactaa tcaaagatag ggccaaatct aatacttttt tcccatctaa
     9121 cataccatag tccatcatcg gaataacagc tatcggaaca tcacacttat cacaaatttc
     9181 ttttgattta tctaatgtat aagcaacttg tggacccaat agtgcaacat ctatatttgg
     9241 cgcataatcc gctaatttag actgagaaaa cgcctctatt tctgcctcaa ctccactaga
     9301 ttgcgctgca attttcatat tatttacaag cataccagta gaaaaacctg ctgcacaaaa
     9361 caaaccaatc ttcaccatta tgttttcctc ctctatgtta ataacaatga taatactcta
     9421 gtattatttt ttatgaagtt cttttctcaa actaataatt tctttgatta aattaatctc
     9481 cgtcatacta gtcatgagat gatcttgtga atgaacaaag agagctgtaa tttctgtctt
     9541 tgtaccagac gcttcctgtg ccaagaattt tgtttgtaga ttatgagctt ctaataaggc
     9601 tgcatcagct aactggattt cttcttcaca tcgttcacat gtaccgttct ttatgtaatc
     9661 taatgcttta taaatatgtt gtttcgcatc gccagcatat aaaattaaac ccatgataat
     9721 ttgatctgga acaataattt ccataaattc ctcctcattt cactatgtaa aaagcttttt
     9781 tcatttgaaa tttt
//
LOCUS       DAVLXH010000067         9680 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00028199
            SAMN33607166-rid17955573.denovo.068, whole genome shotgun sequence.
ACCESSION   DAVLXH010000067 DAVLXH010000000
VERSION     DAVLXH010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607166
            Sequence Read Archive: SRR23725544
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9680)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9680)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721421.1
            Genome Coverage       :: 115x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:42:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,210
            CDSs (total)                      :: 2,161
            Genes (coding)                    :: 2,023
            CDSs (with protein)               :: 2,023
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 73 of 138
            Pseudo Genes (incomplete)         :: 60 of 138
            Pseudo Genes (internal stop)      :: 40 of 138
            Pseudo Genes (multiple problems)  :: 31 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9680
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607166-rid17955573.denovo.068"
                     /strain="AUSMDU00028199"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1349"
     gene            189..284
                     /locus_tag="VYO11_001886"
                     /pseudo
     CDS             189..284
                     /locus_tag="VYO11_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(537..1157)
                     /locus_tag="VYO11_001887"
     CDS             complement(537..1157)
                     /locus_tag="VYO11_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEV1596392.1"
                     /translation="MKLYFVRHGRTLWNQEGRFQGASGDSPLLPGSIETLKRLGQYLK
                     EIPFDQIYSSDLPRAVKSAEIIQSQLHTPCSLEIVPNLREWQLGKLEGLKIATLEAIY
                     PQQIQAFRSNLAQFDTRMFGAESLYSTTQRTIQFIKSLKDSPAERILIVGHGANLTAS
                     LRTLLGYKEPLLRKDGGLANASLTIIETHDFETFTLNTWNDTSYQS"
     gene            complement(1157..1639)
                     /locus_tag="VYO11_001888"
     CDS             complement(1157..1639)
                     /locus_tag="VYO11_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HEV1596393.1"
                     /translation="MAKKVKIKKTLVEQILSKAAIPHQGIQINALEGELPQGYERDQI
                     FKTLALLGDKTGPIIGIVPITQHLSEKKLAKISGNKKVSMIPQKDLEKTTGYIHGANN
                     PVGIRQKHNYHIFIDKIALDLDRMIVSAGEVGHSIIVAPQDLASFVKADFVDILEDIK
                     "
     gene            complement(1639..2481)
                     /locus_tag="VYO11_001889"
     CDS             complement(1639..2481)
                     /locus_tag="VYO11_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HEV1596394.1"
                     /translation="MLSWLARVIKGIVIALGFILPGISGGVLAAILGIYERMIGFLAH
                     PFKDLKENVLYFIPVAIGMLLGIGLFSYPIEYLLENYQVFVLWSFAGAIIGTVPSLLK
                     ESTRESDRDKIDLAWLWTTFIISGLGLYALNFVVGTLSASFLNFVLAGALLALGVLVP
                     GLSPSNLLLILGLYAPMLTGFKTFDLLGTFFPIGIGAGATLIVFSKLMDYALNNYHSR
                     VYHFIIGIVLSSTLLILIPNAGNAESIQYTGLSLVGYVIIAFFFALGIWLGIWMSQLE
                     DKYK"
     gene            complement(2576..3376)
                     /locus_tag="VYO11_001890"
     CDS             complement(2576..3376)
                     /locus_tag="VYO11_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 25 protein"
                     /protein_id="HEV1596395.1"
                     /translation="MRKQIHPLILFSFLGIMMFILIINRPLNDSQSFKTKSNIAQIEA
                     QALKHLDKPIIDLSGWQRPEEINYDALSQNISGAIVRVHSGAQTTKENDASFINGIDK
                     AYKSHITELQKRNVPVAVYAYVAGKSAQEMEKAAEVFYNAASPYSPSYYWLDVEDKTM
                     SNMNEGVENFRAKLASLGAKNIGIYVGVYFMEEHSIDTGKFTSVWIPSYGSDSGFLES
                     SPKTDLDYDIHQYTSKGKIAGFDHDLDINVISPLKNKEETFRKLFLKP"
     gene            3520..4899
                     /gene="glmU"
                     /locus_tag="VYO11_001891"
     CDS             3520..4899
                     /gene="glmU"
                     /locus_tag="VYO11_001891"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HEV1596396.1"
                     /translation="MSNFAIILAAGKGTRMKSDLPKVLHKVAGISMLEHVFRSVGAIQ
                     PEKTVTVVGHKAELVEEVLAGQTEFVTQSEQLGTGHAVMMTEPILEGLSGHTLVIAGD
                     TPLITGESLKNLIDFHINHKNVATILTAETDNPFGYGRIVRNDNAEVLRIVEQKDATD
                     FEKQIKEINTGTYVFDNERLFEALKNINTNNAQGEYYITDVIGIFRETGEKVGAYTLK
                     DFDESLGVNDRVALATAESVMRRRINHKHMVNGVSFVNPEATYIDIDVEIAPEVQIEA
                     NVTLKGQTKIGAETVLTNGTYVVDSTIGAGAVITNSMIEESSVADGVTVGPYAHIRPN
                     SSLGAQVHIGNFVEVKGSSIGENTKAGHLTYIGNCEVGSNVNFGAGTITVNYDGKNKY
                     KTVIGDNVFVGSNSTIIAPVELGDNSLVGAGSTITKDVPADAIAIGRGRQINKDEYAT
                     RLPHHPKNQ"
     gene            4909..5454
                     /locus_tag="VYO11_001892"
     CDS             4909..5454
                     /locus_tag="VYO11_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEV1596397.1"
                     /translation="MEFEEKTLSRKEIYQGPIFKLVQDQVELPEGKGTAQRDLIFHNG
                     AVCVLAVTDEQKLILVKQYRKAIEAVSYEIPAGKLEVGENTAPVAAALRELEEETAYT
                     GKLELLYDFYSAIGFCNEKLKLYLASDLTKVENPRPQDEDETLEVLEVSLEEAKELIQ
                     SGHICDAKTIMAVQYWELKKK"
     gene            5466..5780
                     /locus_tag="VYO11_001893"
     CDS             5466..5780
                     /locus_tag="VYO11_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="foldase"
                     /protein_id="HEV1596398.1"
                     /translation="MGKSLLTDEMIERANRGEKISGPPLLDDNEETKILPTSSSRFGY
                     ANPKNHGFSQETLKIQVEPSIHKSRRIENTKRNVFNSKLNKILFAVIFLLILLVLAMK
                     LL"
     gene            5797..6489
                     /locus_tag="VYO11_001894"
     CDS             5797..6489
                     /locus_tag="VYO11_001894"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HEV1596399.1"
                     /translation="MKIGIIAAMPEELAYLVQHLDNAQEQVVCGNTYHTGTIASHEVV
                     LVESGIGKVMSAMSVAILADHFQVDALINTGSAGAVAEGIAVGDVVIADKLAYHDVDV
                     TAFGYAYGQMAQQPLYFESDKTFVAQIQESLSQLDQNWHLGLIATGDSFVAGNDKIEA
                     IKSHFPEVLAVEMEGAAIAQAAHALNLPVLVIRAMSDNANHEANIFFDEFIIEAGRRS
                     AQVLLTFLKALD"
     gene            6566..7057
                     /gene="rocS"
                     /locus_tag="VYO11_001895"
     CDS             6566..7057
                     /gene="rocS"
                     /locus_tag="VYO11_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein RocS"
                     /protein_id="HEV1596400.1"
                     /translation="MSIEMTVSEIAEVLGLSRQAINNRVKELPEEDTDKNDKGVTVVT
                     RSGLIKLEEIYKKTIFEDEPVSEDVKQRELMEILVDEKNAEILRLYEQLKAKDRQLSE
                     KDEQMRIKDRQIAEKDKQLDQQQQLTLQAMKDQENLKLELDQAKEEVQSTKKGFFARL
                     FGG"
     gene            7155..7745
                     /locus_tag="VYO11_001896"
     CDS             7155..7745
                     /locus_tag="VYO11_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HEV1596401.1"
                     /translation="MERLEDYIAFDLEFNQHEGQTHLIQVSAVRFRDGREIDAYDSYV
                     HTSVPLKSFINGLTGITAETLKDAPPVEKVLEEFQEFVGSLLMIGYNAAKSDLPILAE
                     HGLDYSQQYKVDLYDEAFERRSSDLHGIANLKLQTVASFLGFQGQSHNSLEDARMTAR
                     VYESFLESDQARELLETESSLSNNPFGVLDLSQLFD"
     gene            7754..9517
                     /locus_tag="VYO11_001897"
     CDS             7754..9517
                     /locus_tag="VYO11_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HEV1596402.1"
                     /translation="MKPEKPKKLGLKQIYLNLDKILFLFFLIFMIVEYLWVPFNSWLA
                     SFLLDQTGYLFISYNNVLAILTHSPLISLAFLALIVINLLVAYFQIGLLFIGARHLLY
                     NEKRRLIEYIRKVFHESFGFMKKLTGAKALFIFFYIAMLFPFIRKMLKIYYLNKIVIP
                     EFIQAYLEDKYWMWWLSILLLSLIFLYVSVRLMFALPKIVYDQLTVREAVMFSLEKTK
                     KRVTFYAWNLFYILLKAHLLFYLPLIPLLLAQTLVDDITQRESLILGILNFVVIKNLY
                     YMALTYFLVKFVSFLTGKELDMLPRREKDHIVRWGVITCASLFFALEGYIYLEAPMVH
                     LPQLISHRGVSNANGIQNTVESLETTAQLKPDLVETDVQETKDGQFVMMHDANLKNLA
                     GINKSPQDLNLEELKGIDIFENGYQTKISSFEDYLSRANELGQKLLIEIKTSKKDSPD
                     MMNRFLARYAAKLKIYGHQIQSLDYHVVEKVRQYDAELPVYFIMPYNSVFPKTRATGY
                     TMEYSTLDEYFVSKLWTTDQKLYVWTVNDSEAISKSLHLGVDGVITDDLEKVQREIEV
                     AQENPEYTDLLLKKALEFFEF"
BASE COUNT         2988 a         1686 c         2070 g         2936 t
ORIGIN      
        1 aagacttttt gaccagcctc attttttaac ttgatactca gtgaaaagca aagattaaac
       61 taggaagcta gctgtaggct gctcaaagaa cagctttgag gttgcagata aaacttgtga
      121 ggtaaccaac atatataatg tgaagctgac gtggtttgaa tagattttag aagggtatga
      181 gtctggaagt tttaatggat aatgcaagat tccatagaat gggtaagcta gagttcttat
      241 gtgaagagtt tgggcataaa cttttacctt ttcctcccta ctcatcttag tatagaaaag
      301 tgaatctaaa atagtacata actgcttcta aaacattctt ataaattgat ttaaattctc
      361 aaatcatatt attcagttct tatttcattt tgctctacaa tcctgttgag aagacacgtg
      421 ttcatatcaa aaaggtattg gcaagttgca ataccttttt acaaggttct tttgtcttat
      481 ttttgtttca actgactata tctcctatgg ttctagttca gaaggctagg ctataattat
      541 gattgataag aagtatcatt ccaagtattg agagtgaatg tttcaaaatc atgggtttct
      601 ataatggtca ggctggcatt tgctagaccg ccatctttac gaagaagtgg ttctttatag
      661 cctaggagag tacgaagact ggcagtaaga ttggcgccgt gtccgacaat tagaatacgc
      721 tcagctggac tatcttttaa tgatttgata aattggatgg tccgctgagt tgtactatag
      781 agggattcgg ctccgaacat tcgagtgtca aattgagcaa gatttgaacg aaaagcctgg
      841 atttgttgcg ggtaaatagc ttccagggtt gcaattttca aaccttctaa cttcccaagt
      901 tgccattcac ggagattagg aacgatttct aaagaacagg gggtatggag ttgactttgg
      961 ataatctcag cagatttgac cgctcgaggt aaatcacttg aataaatctg atcaaaagga
     1021 atttccttga gatactggcc aagtcgtttt agggtttcaa tggatccagg aagaagagga
     1081 gaatcaccgc tagcaccttg aaaacgacct tcttggttcc agagggtacg accgtggcgg
     1141 acaaagtaga gtttcattac ttgatgtcct ccaaaatatc tacaaagtct gcctttacaa
     1201 agctagccaa gtcttgtggc gcgacgataa tgctgtgtcc gacttcgcct gcagagacaa
     1261 tcattcgatc caaatctaga gcaattttat cgataaaaat gtgataattg tgtttctgac
     1321 gaattccgac aggattattg gctccatgaa tgtaaccagt tgttttttct aagtcctttt
     1381 gtggaatcat gctcactttt ttattgccag aaattttagc tagtttcttt tcagacaagt
     1441 gctgagtgat agggacaatt ccgataatcg gtccggtctt gtctcccaaa agcgccaagg
     1501 ttttgaaaat ctgatctcgt tcataacctt gaggaagctc tccttctagg gcattgattt
     1561 gaatcccctg atgagggata gctgctttag ataggatttg ttccaccaat gtttttttga
     1621 ttttaacttt ttttgccatt atttatattt atcctccaat tgactcatcc aaataccaag
     1681 ccagattccc agcgcaaaga agaaggcgat gatgacataa ccgacaagtg aaagtcctgt
     1741 gtattggata ctttcagcgt ttcctgcatt tggaattaag atcaaaaggg tacttgatag
     1801 gacgataccg atgatgaaat gatagacgcg tgagtggtag ttgtttaagg cataatccat
     1861 caattttgaa aaaacgatga gagttgcacc tgcaccaatt ccaatcggaa agaaggttcc
     1921 caagagatca aaagttttaa aaccagtcaa cataggagca tagagtccca aaatcaaaag
     1981 taaattcgat gggctgaggc caggaaccaa gacgccaagg gccaatagtg cgcctgctag
     2041 gacgaagtta agaaagctgg cgcttaaggt tccaacgaca aaatttaagg catagagtcc
     2101 taatccagaa atgataaagg ttgtccataa ccaagctaaa tcaatcttgt ctcggtcaga
     2161 ttctcgagtt gattctttga ggaggctagg aactgtaccg ataatagctc ccgcaaagct
     2221 ccataataca aagacctgat aattttcaag caggtattca atcgggtagg aaaataagcc
     2281 gattcccaga agcataccga tggcaactgg aataaagtac aaaacatttt ctttaaggtc
     2341 tttaaaggga tgggccagaa agccaatcat tcgttcatag attcctaaga ttgctgctag
     2401 aacccctccg gaaattcctg gtaggataaa tccaagagca attacaatcc ctttaataac
     2461 gcgtgctaac catgagagca tatatttcct ccaactattt ctatttcaaa aaatccttac
     2521 tatattgtat cacaatcaga cacaaaaaga aaaagcaaat gataaacaaa tgcttttaag
     2581 gttttaaaaa aagttttcga aaggtttctt ctttattttt taagggagag ataacgttga
     2641 tatctaaatc gtggtcaaag ccggcaattt ttcctttaga tgtgtattgg tgaatatcat
     2701 aatctaaatc agttttagga ctgctctcca aaaatcctga gtctgagccg taggacggaa
     2761 tccaaacaga ggtaaacttg cctgtatcaa tactgtgttc ttccatgaag tagacaccaa
     2821 cgtagatgcc gatgttttta gcacctagtg atgctagttt tgctcgaaag ttttcgacac
     2881 cttcgttcat attagacatg gttttgtctt ccacgtcaag ccaatagtaa ctagggctgt
     2941 aaggagaggc agcattgtag aaaacttcgg cagccttttc catttcttgg gcactttttc
     3001 cagctacata agcgtagaca gcaactggga cattccgctt ttgaagttca gtgatatgac
     3061 tcttataggc cttgtctatt ccattgataa atgaagcatc attttctttt gtcgtttgag
     3121 caccactgtg aacacgaaca atagcacctg aaatattttg tgagagggca tcgtagttga
     3181 tttcctcagg acgctgccag ccagagaggt caataatcgg tttgtctaag tgtttcaaag
     3241 cctgtgcttc aatctgtgct atattggatt ttgttttaaa cgattggctg tcattaagtg
     3301 ggcgattgat gattaaaatg aacatcataa tccccaaaaa actaaataaa ataagtggat
     3361 gaatttgttt tctcatatct tataattcta ccctaaaaat caaaaaaaat caaaaaaatg
     3421 ggttaaggaa gagactttag agcatttttt cattcaagag tgcggaatga tttgaaatat
     3481 ggtataataa aagggaattt ctacagaaaa gagaagatta tgtcaaattt tgccattatt
     3541 ttagcagcgg gtaaagggac tcgcatgaaa tctgatttgc caaaagtttt gcacaaggtt
     3601 gcgggtattt ctatgttgga acatgttttc cgtagtgtgg gagctatcca acctgaaaag
     3661 acagtaacag ttgtaggaca caaggcagaa ttggttgagg aggtcttggc tggacagaca
     3721 gaatttgtga ctcaatctga acagttggga actggtcatg cagttatgat gacagagcct
     3781 atcttagaag gtttgtcagg acacaccttg gtcattgcag gagatactcc tttaatcact
     3841 ggtgaaagct tgaaaaactt gattgatttc catatcaatc ataaaaatgt ggccactatc
     3901 ttgactgctg aaacggataa tccttttggc tatggacgaa ttgttcgtaa tgacaatgct
     3961 gaggttcttc gtattgttga gcagaaggat gctacagatt ttgaaaagca aatcaaggaa
     4021 atcaacactg gaacatacgt ctttgacaac gagcgtttgt ttgaggcttt gaaaaatatc
     4081 aataccaata acgctcaagg cgaatactat attacagacg tcattggtat tttccgtgaa
     4141 actggtgaaa aagttggcgc ttatactttg aaagattttg atgaaagtct tggggtaaat
     4201 gaccgtgtgg cgcttgcgac agctgagtca gttatgcgtc gtcgcatcaa tcataaacac
     4261 atggtcaacg gtgttagctt tgtcaatcca gaagcaactt atatcgatat tgatgttgag
     4321 attgctccgg aagttcaaat cgaagccaat gttaccttga aagggcaaac gaaaattggt
     4381 gctgagactg ttttgacaaa cggtacttat gtagtggaca gcactatcgg agcaggagcg
     4441 gtcattacca attctatgat tgaggaaagt agtgttgcag acggtgtgac agtcggtcct
     4501 tatgctcaca ttcgtccaaa ttcaagtctg ggtgcccaag ttcatattgg taactttgtt
     4561 gaggtgaaag gatcttcaat cggtgagaat accaaggctg gtcatttgac ttatatcgga
     4621 aactgtgaag tgggaagcaa cgttaatttc ggtgctggaa ctattacagt caattatgac
     4681 ggcaaaaaca aatacaagac agtcattgga gacaatgtct ttgttggttc aaattcaacc
     4741 attattgcac cagtagaact tggtgacaat tccctcgttg gtgctggttc aactattact
     4801 aaagacgtgc cagcagatgc tattgctatt ggtcgcggtc gtcagatcaa taaagacgaa
     4861 tatgcaacac gtcttcctca tcatcctaag aaccagtagg agcctatcat ggagtttgaa
     4921 gaaaaaacgc ttagccgaaa agaaatctat caaggaccaa tatttaaact ggtccaagat
     4981 caggttgaat taccagaagg caagggaact gcccaacggg atttgatttt ccacaatggg
     5041 gctgtctgtg ttttagcagt aacggatgaa caaaaactta tcttggtcaa gcagtaccgc
     5101 aaagctatcg aggctgtctc ttacgaaatt ccagccggaa aattggaagt aggagaaaac
     5161 acagcccctg tggcagctgc ccttcgtgaa ttagaggaag aaacagccta tacagggaaa
     5221 ttagaactct tgtacgattt ttattcagct attggctttt gtaatgagaa gttaaaacta
     5281 tatttagcaa gcgatttgac aaaagtggaa aatccgcgtc cgcaggatga ggatgaaacc
     5341 ttggaagtcc ttgaagtgag cttagaagaa gcgaaagaat taatccaatc aggtcatatt
     5401 tgtgatgcca agacaattat ggctgttcag tattgggagt tgaagaaaaa atagaggagg
     5461 tcagtatggg taaatcttta ttaacggatg aaatgattga aagagctaat agaggcgaaa
     5521 aaatttcagg tcctcctttg ctagatgata atgaggagac taagatttta ccaacctctt
     5581 cttcccgttt tggttatgcc aatcctaaga atcatggttt tagccaggaa accttgaaga
     5641 ttcaggtcga accatctatt cataaaagcc gtcgcattga aaataccaag agaaatgtct
     5701 tcaattctaa gttgaataaa atcttattcg cggtcatctt tctcttgatt ttgcttgttt
     5761 tagcaatgaa acttttgtaa tagaaaagga attgaaatga aaataggaat tattgctgct
     5821 atgccagaag aactggctta tctggtccag catttagata atgcccagga gcaagttgtt
     5881 tgtgggaata cctatcatac aggaaccatt gcttctcatg aagtcgttct tgtagaaagt
     5941 ggaattggta aggtcatgtc tgctatgagt gtggcgattt tggctgatca tttccaggtg
     6001 gatgccctta ttaatacggg ttcagctggg gcagtagcag aaggtatcgc tgttggggat
     6061 gtcgtgattg ctgacaaatt agcctatcat gacgtggatg tcacagcttt tggctatgct
     6121 tatggacaaa tggcgcaaca accgctttat ttcgaatcag acaaaacctt tgttgctcaa
     6181 atccaagaga gtttatctca attggaccaa aactggcatc ttggtttgat tgctacagga
     6241 gatagttttg ttgcaggaaa tgacaagata gaagcgatta agtcccattt cccagaagtt
     6301 ttagccgtgg agatggaggg ggcagctatt gctcaagcag cgcatgccct caatctccca
     6361 gtcttagtca tcagagctat gagtgacaat gccaaccatg aagcaaacat cttttttgat
     6421 gagtttatta tcgaagctgg acgtcgctct gcccaagtct tgttgacctt tttgaaggct
     6481 ttagattaag cggaaatttg acagtttttc tagcttatga taagatttaa gtaaagaaaa
     6541 gctagaaaac gtttcagagg atattatgag tattgaaatg accgtcagtg agattgcaga
     6601 ggtcttagga ttatctcgcc aagcaatcaa taaccgtgtc aaagaattac cagaagaaga
     6661 cacagataaa aatgacaaag gggtaacagt tgttaccaga agtggcttga ttaagctaga
     6721 agaaatctat aaaaaaacga tttttgaaga tgagcctgtc agtgaagatg tcaaacaacg
     6781 tgaactgatg gagattctag tggatgagaa gaatgcagaa attcttcgtc tttatgaaca
     6841 attaaaagcc aaggatcgtc agttatcaga aaaagacgag cagatgcgta tcaaagaccg
     6901 tcagattgct gagaaagaca aacaattaga tcagcaacaa caattgaccc ttcaagccat
     6961 gaaggatcaa gaaaatctta agctagagct ggaccaagca aaagaagaag tccaatccac
     7021 taagaaaggc ttttttgctc gtttatttgg aggataatca aggagctgtt taggttaaat
     7081 gctaacctga tggcttcttt tgtttgtgaa tagtatagtt gattagaaca gagacagtag
     7141 aggagaggaa cagaatggaa cgattagaag attacattgc ttttgactta gaatttaatc
     7201 agcacgaagg acaaacacac ttgattcaag tatcggcagt gcgttttaga gatggtcggg
     7261 aaatcgatgc ctatgattcc tatgttcata ccagcgtccc tctaaaaagc tttatcaatg
     7321 gtttgaccgg gattacagct gagaccttaa aagatgctcc tccagttgag aaagtcttag
     7381 aagaattcca agagtttgtg ggttctttgc tgatgatagg ctacaatgct gctaaaagtg
     7441 atttacctat tttagcagag catggtttag actatagcca acagtacaag gtggatttgt
     7501 atgatgaagc ttttgaacgt cggagttcag atttacatgg tattgccaat ctcaaattgc
     7561 aaactgttgc ctcatttctt ggatttcaag gtcagtctca taatagttta gaggatgctc
     7621 ggatgacggc gcgtgtttac gaatccttct tagagtcgga tcaagctagg gaattgttag
     7681 agacagaaag tagcttatca aacaatcctt ttggtgtctt ggacttgtct caattatttg
     7741 actaggagtg cctatgaaac ctgaaaaacc taaaaaattg ggtcttaaac agatttacct
     7801 caatcttgat aaaatcctct ttctattttt cttgattttt atgatagtgg agtatttgtg
     7861 ggtaccattc aattcatggt tggctagctt cttattagat cagacaggtt atctttttat
     7921 ttcctataac aatgtcttag ccatccttac tcattctcca ttgattagtc tagctttttt
     7981 agccttgatt gtaattaacc ttctggttgc ttattttcaa ataggactcc tctttattgg
     8041 tgctcgtcat ctcctctata atgaaaagcg aaggctaatt gagtatatcc gcaaggtttt
     8101 ccatgaaagt tttggattta tgaaaaagct aactggcgct aaagccttgt ttatcttttt
     8161 ctatatagct atgctttttc cttttatacg gaaaatgctg aagatttatt atcttaataa
     8221 aatcgtcatt ccagagttta tccaagctta tttagaagat aaatattgga tgtggtggct
     8281 gagcatccta cttctatctc ttatctttct ctatgtctct gtcagattga tgtttgccct
     8341 tccgaagatt gtatatgatc agctgactgt tcgagaagca gtgatgttta gcttggagaa
     8401 aaccaagaag agagttactt tttatgcttg gaatttattt tacatcttgc tcaaagcaca
     8461 tttattattt tatcttcctt tgattccttt attattggct caaactttgg tagatgatat
     8521 cactcagaga gagtctctga ttcttggtat tttgaatttt gtcgtgatta aaaatctcta
     8581 ttatatggct ctgacttatt ttttggttaa atttgtttca tttttgacag gaaaggagct
     8641 ggatatgctt cctaggagag aaaaagatca catcgtgcga tggggtgtca taacttgtgc
     8701 cagtcttttc tttgccttag aaggttatat ttatctggag gctcccatgg ttcatctacc
     8761 tcaacttatt tctcaccgag gggtttccaa tgcaaatggg attcaaaata cagtagagtc
     8821 cttggaaact acagcacaac tcaaaccaga cttggtggag acggacgtgc aggaaacaaa
     8881 agatgggcag tttgtcatga tgcatgatgc taacttgaaa aatctagcag gtatcaataa
     8941 aagtcctcaa gacttaaact tggaggagct taaagggatt gatatttttg aaaatggcta
     9001 ccagactaaa atttcaagct ttgaagatta tctcagtcga gccaacgaac ttggtcaaaa
     9061 attactaatt gaaattaaaa ccagtaaaaa agatagtcca gacatgatga accgcttttt
     9121 agcccgttat gctgcaaagc tcaagattta tggacatcaa atccagtctt tagactacca
     9181 tgttgtcgaa aaagtaagac agtatgatgc cgaactgcca gtttatttca tcatgcccta
     9241 caattctgtc tttcctaaaa caagagcgac aggatatact atggagtact caaccttgga
     9301 tgaatatttt gtaagcaaac tatggacaac ggatcagaaa ctttatgtct ggactgtcaa
     9361 tgattcagaa gctatcagca aatctcttca cttaggagta gatggagtga ttacagatga
     9421 tttggaaaaa gttcagcggg aaatagaagt agcccaagaa aatccagaat atacggattt
     9481 gctcttgaaa aaagcattgg aattctttga attttagtaa taaaaaagag gaacggttgt
     9541 tcctcccatg ataggtaagt attcttgtga atgcttgctt ttttgtggtt gcaatccgtt
     9601 tacgagaatt gtttgtattg ttcttgtttc aatttacttt atagtgcttt gaagttggaa
     9661 tgctacacta taacttctaa
//
LOCUS       DAVLXH010000068         9605 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00028199
            SAMN33607166-rid17955573.denovo.069, whole genome shotgun sequence.
ACCESSION   DAVLXH010000068 DAVLXH010000000
VERSION     DAVLXH010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607166
            Sequence Read Archive: SRR23725544
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9605)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9605)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721421.1
            Genome Coverage       :: 115x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:42:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,210
            CDSs (total)                      :: 2,161
            Genes (coding)                    :: 2,023
            CDSs (with protein)               :: 2,023
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 73 of 138
            Pseudo Genes (incomplete)         :: 60 of 138
            Pseudo Genes (internal stop)      :: 40 of 138
            Pseudo Genes (multiple problems)  :: 31 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9605
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607166-rid17955573.denovo.069"
                     /strain="AUSMDU00028199"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1349"
     gene            <1..629
                     /locus_tag="VYO11_001898"
     CDS             <1..629
                     /locus_tag="VYO11_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000380539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="V-type ATPase subunit"
                     /protein_id="HEV1596403.1"
                     /translation="HLVSSLHSDTLPDFMVREVESIWNEYETFNNIRVLDVGADLAYF
                     KHLKLLSNELDEVLSQVIVEMIDFYNIITVKRGLSQNKSHGDILQLLSDEGSISAKEF
                     IYIVENQEIFVWFNKINPSLDSIFSTYELKMQDATISSSELEFLCDLLLYKTLDQGRY
                     NVEGPLVLARYLLGCEFEVKNLRMIISALQNTIPFESIKERIRPHYGS"
     gene            619..939
                     /locus_tag="VYO11_001899"
     CDS             619..939
                     /locus_tag="VYO11_001899"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000387939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit F"
                     /protein_id="HEV1596404.1"
                     /translation="MEANKYKIGIIGSRDIILPFSMIGFDIFPAYQEQEAINTLRKLA
                     QSDYGVIYITEDIASMILDTIRHYDSQVVPAIILLPTHKQGLNLGLKRIEDNVEKAVG
                     HNIL"
     gene            1002..2777
                     /locus_tag="VYO11_001900"
     CDS             1002..2777
                     /locus_tag="VYO11_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit A"
                     /protein_id="HEV1596405.1"
                     /translation="MTQGKIIKVSGPLVIASGMQEANIQDICRVGKLGLIGEIIEMRR
                     DQASIQVYEETSGLGPGEPVVTTGEPLSVELGPGLISQMFDGIQRPLDRFKLATHNDF
                     LVRGVEVPSLDRDIKWHFDSTISIGQKVSTGDILGTVKETEVVNHKIMVPYGISGEVV
                     SIASGDFTIDEVVYEIKKLDGSFYKGTLMQKWPVRKARPVSKRLIPEEPLITGQRVID
                     TFFPVTKGGAAAVPGPFGAGKTVVQHQVAKFANVDIVIYVGCGERGNEMTDVLNEFPE
                     LIDPNTGQSIMQRTVLIANTSNMPVAAREASIYTGITMAEYFRDMGYSVAIMADSTSR
                     WAEALREMSGRLEEMPGDEGYPAYLGSRIAEYYERAGRSQALGLPEREGTITAIGAVS
                     PPGGDISEPVTQNTLRIVKVFWGLDAPLAQRRHFPAINWLTSYSLYKDSVGTYIDDKE
                     KTDWNSKITRAMNYLQRESSLEEIVRLVGIDSLSENERLTMEIAKQIREDYLQQNAFD
                     SVDTFTSFAKQEAMLSNILTFADQANHALELGSYFTEIIEGTVAVRDRMARSKYVSED
                     RLDEIKIISNEITHQIQLILETGGL"
     gene            2778..4163
                     /locus_tag="VYO11_001901"
     CDS             2778..4163
                     /locus_tag="VYO11_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000111247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit B"
                     /protein_id="HEV1596406.1"
                     /translation="MSVIKEYRTASEVVGPLMIVEQVNNVSYNELVEIQLHNGEIRRG
                     QVLEIHEDKAMVQLFEGSSGINLEKSKIRFAGHALELAVSEDMVGRIFNGMGKPIDGG
                     PDLIPEKYLDIDGQAINPVSRDYPDEFIQTGISSIDHLNTLVRGQKLPVFSGSGLPHN
                     ELAAQIARQATVLNSDENFAVVFAAMGITFEEAEFFMEELRKTGAIDRSVLFMNLAND
                     PAIERIATPRIALTAAEYLAFEKDMHVLVIMTDMTNYCEALREVSAARREVPGRRGYP
                     GYLYTNLSTLYERAGRLVGKKGSVTQIPILTMPEDDITHPIPDLTGYITEGQIILSHE
                     LYNQGYRPPINVLPSLSRLKDKGSGEGKTRGDHAPTMNQLFAAYAQGKKVEELAVVLG
                     ESALSDVDKLYVKFTKRFEEEYINQGFYKNRNIEDTLNLGWELLSILPRTELKRIKDD
                     LLDKYLPLVEV"
     gene            4186..4797
                     /locus_tag="VYO11_001902"
     CDS             4186..4797
                     /locus_tag="VYO11_001902"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000251933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HEV1596407.1"
                     /translation="MVRLNVKPTRMELNNLKERLKTAERGHKLLKDKRDELMRRFISL
                     IRENNQLRKEVESYLIDNLKAFAVAKSLKNSLMVEELFSIPSKEIELFVEKENIMSVT
                     VPRMHMNITSQNENSEYSYLSSNSEMDDVFATMNSLIDKLLRLAEVEKTCQLMADEIE
                     KTRRRVNGLEYSIIPNLSETIHYIELKLEEAERANLVRIMKVK"
     gene            4873..5076
                     /locus_tag="VYO11_001903"
     CDS             4873..5076
                     /locus_tag="VYO11_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000218559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1596408.1"
                     /translation="MTVSGYLFQNFGLLDNENVSTDLDLGLISRKCNFKEKDKLKKDV
                     LARVGLTHIHLEQKIYELSGGEA"
     gene            5173..5283
                     /locus_tag="VYO11_001904"
     CDS             5173..5283
                     /locus_tag="VYO11_001904"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1596409.1"
                     /translation="MKLLLDMKNENRLIIIATHNPDIWNQADEVINLNQL"
     gene            complement(5383..6734)
                     /locus_tag="VYO11_001905"
     CDS             complement(join(5383..6293,6293..6734))
                     /locus_tag="VYO11_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611513.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3-like element ISSpn4 family transposase"
                     /protein_id="HEV1596410.1"
                     /translation="MKLSYEDKVQIYELRKQGYSLEKISNKFEINNSNLRYMIKLIDR
                     YGIEFIKKGKNRYYSPELKQEMIDKVLHENWSQDRVSLKYALPNRGMLPNWLAQYKKN
                     GYTIVEKTRERVPKMGRKRKKTWEEMTELERLQEENERLRTEVAYFKKVKRAGRQGRS
                     PRARKAEIVREMASGGFQLDLLLETARLARSTYYYQLKGLGGLDKDKDLKAEIQAIFT
                     EHKGNYGYRRVTLELRNRGFVVNHKKVQRLMKVLGLTARIRRKRKYSSYQGEIGKKAE
                     NLIQRQFEASRPMEKCYTDVTEFAIPASSQKLYLSPVLDGFNSEIIAYNLSTSPNLEQ
                     GKAMLNQAFTEKHYENTILHSDQGWQYQHDSYHRFLESKGIQASMSRKGNSPDNGMME
                     SFFGILKSEMFYGYEKTFQSLNQLEQAIVDYIDYYNNKRIKIKLKGLSPVQYRTKSFG
                     "
     gene            7319..7537
                     /locus_tag="VYO11_001906"
                     /pseudo
     CDS             7319..7537
                     /locus_tag="VYO11_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000869756.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(7837..8124)
                     /locus_tag="VYO11_001907"
                     /pseudo
     CDS             complement(7837..8124)
                     /locus_tag="VYO11_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            8123..8386
                     /locus_tag="VYO11_001908"
                     /pseudo
     CDS             8123..8386
                     /locus_tag="VYO11_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            8403..8981
                     /locus_tag="VYO11_001909"
                     /pseudo
     CDS             8403..8981
                     /locus_tag="VYO11_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151458.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
     gene            8994..9164
                     /locus_tag="VYO11_001910"
     CDS             8994..9164
                     /locus_tag="VYO11_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1596411.1"
                     /translation="MKKENEYVILTTASLGVMIGIVFAIFLDFPVEYGISLGLLNGIV
                     LGSLIVYKNNKN"
BASE COUNT         3164 a         1476 c         1851 g         3114 t
ORIGIN      
        1 aacatttagt ttcttcctta cattcagata cacttcctga ttttatggtt cgtgaagtag
       61 aatcaatttg gaatgagtat gaaactttta ataatattcg tgtacttgat gtcggagctg
      121 atctagcata ttttaaacat ctgaaacttt tatctaatga gttagatgag gtactgtctc
      181 aggttattgt cgaaatgatt gacttttata atattattac tgtaaaacgt ggtttatctc
      241 aaaataagag tcatggggat attttacaat tactttcaga tgaaggaagt atttctgcta
      301 aagaatttat atacattgta gaaaatcaag aaatatttgt gtggttcaat aaaataaatc
      361 caagcttaga ttcaatcttt tcaacttatg aattgaagat gcaggacgca acaatttcat
      421 cttctgagtt agaattttta tgtgatttac tattgtataa aactttagat caaggaaggt
      481 acaatgtaga ggggccgtta gttcttgcta gatatttatt gggatgtgag tttgaagtaa
      541 agaatctcag aatgatcata tcagctcttc aaaatacaat tccctttgaa tcaataaaag
      601 aaaggatacg cccacattat ggaagctaat aagtataaaa ttggcataat tggtagccgt
      661 gatattattt taccatttag catgattggg tttgatatat ttcctgccta ccaagaacaa
      721 gaagctataa atacactaag aaaattagct caatctgatt atggtgtcat ttatatcact
      781 gaagacattg cttcaatgat attagataca attcgccatt atgattccca agttgtgcct
      841 gctattattt tattaccgac tcataaacaa ggtttaaatt taggattaaa acgtatagag
      901 gataatgtag agaaagcagt aggacacaat attttataat aatgtacaaa attgtctgta
      961 atattattct ataatttttg gacttagtaa ggagaataac tttgactcaa gggaagatta
     1021 taaaagtatc gggacctcta gttattgcat caggtatgca ggaggctaat attcaagata
     1081 tttgccgtgt aggtaagcta gggttaatcg gtgaaattat tgaaatgaga agagatcagg
     1141 catctatcca agtctatgaa gaaacatctg gtcttggtcc gggagaacct gttgttacaa
     1201 ctggagaacc tctctcggtt gaattagggc ctggattgat ttctcaaatg tttgatggca
     1261 tacaacgccc attagatcga tttaaattgg ctactcataa tgattttcta gttcgtgggg
     1321 tagaagttcc aagtttggat agagatatta agtggcattt tgattccact atatcaattg
     1381 gtcaaaaagt gagtacgggt gatattcttg gaactgtcaa ggaaaccgaa gtagttaatc
     1441 ataaaattat ggttccttat ggaatatctg gcgaagtcgt ttctattgcc tctggcgatt
     1501 ttacaattga tgaagttgta tatgaaataa aaaaattgga cggtagtttc tataaaggaa
     1561 cacttatgca aaaatggcct gtccgcaagg cgcgtcctgt ttctaaacgt ttaatcccag
     1621 aagaaccatt aatcacaggt caacgagtta ttgatacatt ctttccagta accaaagggg
     1681 gagcagcagc tgttcctgga ccgtttggag caggaaagac agttgtacaa caccaagtag
     1741 ctaaatttgc caatgttgat attgttattt atgtcggttg tggagaacgt ggaaatgaaa
     1801 tgacggatgt actgaatgag tttcctgagt tgattgaccc taatacagga caatcaatta
     1861 tgcaacggac agttctgatt gctaatactt caaatatgcc tgttgctgct cgtgaggctt
     1921 caatttatac aggaattacc atggctgagt attttcgtga tatgggctac tctgtcgcca
     1981 ttatggctga ttcgacttca cgttgggcag aagcgctacg tgaaatgtca ggacgtctag
     2041 aagaaatgcc tggtgatgag ggttatcctg cttatcttgg aagtcgtatc gctgaatatt
     2101 atgaaagagc gggacgttct caggctctag ggcttccaga acgtgaagga acgattactg
     2161 ctattggagc tgtatcgcca cccggtggag atatttcaga accagttact caaaacactt
     2221 tacggattgt gaaagttttt tgggggcttg atgctccgtt ggcacagcga cgtcattttc
     2281 ctgcaattaa ctggcttacc tcttattcac tctataaaga cagtgtggga acttatatag
     2341 atgataaaga gaagacagat tggaatagta aaataactcg tgcgatgaac tacttacaac
     2401 gggaatctag tttagaggaa attgttcgtc ttgttggaat tgattctctg tctgaaaatg
     2461 aacgactaac gatggaaatt gctaaacaaa ttagagaaga ttatttgcaa cagaacgctt
     2521 ttgattcggt agatacattc acttcgtttg caaaacaaga agcaatgtta agtaatatcc
     2581 taacttttgc tgatcaggca aatcatgctt tagagttggg ttcttacttt acagagatta
     2641 tagaaggtac cgtggcagtt cgagaccgta tggcgagaag taaatatgtt tcagaagata
     2701 gattagatga aatcaaaatt atttcaaatg agattacaca tcaaattcaa ttgatattag
     2761 aaacaggagg tctataaatg agtgttataa aagaatatag aactgctagt gaagttgttg
     2821 ggcctcttat gattgttgaa caagttaata atgtgtctta caatgagtta gttgaaattc
     2881 aacttcataa tggagaaatt cgtcgtggac aagttttaga gatccacgaa gataaagcaa
     2941 tggttcagct ttttgaagga tctagtggaa taaatttaga aaagtctaaa attcgttttg
     3001 ctggtcatgc actagaattg gctgtatctg aggatatggt tggtagaatt tttaatggga
     3061 tgggaaaacc aattgatggt ggaccagatt taattccaga gaaatattta gatattgatg
     3121 gtcaagctat taatcctgta tctagagatt atccagatga atttattcag acagggatct
     3181 cctctattga tcatttgaat actcttgtac gtggtcaaaa attaccagta ttttcaggtt
     3241 cgggcttacc tcataatgaa ttagcagctc agatagcaag acaagcgact gttttaaatt
     3301 ctgatgaaaa ttttgcggtt gtatttgcag caatgggtat tacttttgaa gaagctgagt
     3361 tctttatgga agaactcaga aaaacaggag cgatcgatcg ttcagtctta tttatgaact
     3421 tggcaaatga tcctgcaatt gagcgtattg caactccccg cattgcttta actgcggcag
     3481 agtatctagc ttttgaaaaa gatatgcatg ttctagttat catgacggat atgactaact
     3541 attgtgaagc gttacgtgaa gtctcggcag ctcgccgtga agttccaggt agacgaggct
     3601 atccgggata tttatataca aatttatcaa ctctatacga aagggctggt cgcttagttg
     3661 gtaaaaaagg ttcagtgaca cagattccta ttttaacaat gccagaagat gacataacac
     3721 atccaattcc tgatttaact ggatacatta ctgaagggca aattattttg tcgcatgagt
     3781 tgtataatca aggttatcgt ccaccaatca atgttttacc ttctctctct cgattaaaag
     3841 ataagggatc tggagaaggt aaaactcgtg gagatcatgc tccaactatg aatcaactgt
     3901 ttgcagccta tgcccaaggg aaaaaggttg aagagttagc agtagtatta ggagaatcgg
     3961 ctttatctga tgtagataaa ttgtatgtga agtttacaaa gcgttttgaa gaagagtaca
     4021 tcaaccaagg attttataaa aatcgaaata ttgaagatac gttgaatctt gggtgggaat
     4081 tactatcaat tcttcctaga acagagttaa aacgtatcaa agatgatttg cttgataaat
     4141 acttaccttt ggtagaagtt taatccagaa atggagtgat tatctatggt gcgtttgaat
     4201 gtaaaaccaa ctcgtatgga attgaataac ttaaaggaac gtttgaaaac agctgaacgt
     4261 ggacataagt tattaaagga taaaagagat gaattgatga ggcgatttat ttctttgatt
     4321 cgtgagaata atcaacttcg gaaagaagta gaaagttatc taattgataa tctaaaagcc
     4381 tttgcagttg ctaaatcatt aaagaactct ctaatggtgg aggaattatt ttcaattcca
     4441 tcgaaagaaa ttgaattatt tgttgagaaa gaaaatatca tgagtgtaac agttcctaga
     4501 atgcatatga atattacttc tcaaaatgag aacagtgaat acagctattt atcttctaat
     4561 agtgaaatgg atgatgtatt tgctacaatg aatagtttaa ttgataaatt actaagactg
     4621 gcagaagttg aaaaaacgtg tcagttaatg gctgatgaaa tagaaaaaac acgtagacgt
     4681 gtaaatggat tagaatattc gattattcca aacttgtcag aaactattca ttatatagaa
     4741 ttgaaactag aggaggcaga aagagccaat ttagttcgga ttatgaaagt gaagtagatc
     4801 ctttatttag attttaatta gatgaaccaa tatcagcttg gataaggcgg taagcctttc
     4861 taagcttttt tattgacagt atcaggatat ctttttcaaa attttggttt gttagataat
     4921 gaaaatgttt ctaccgattt agatttagga ttaataagtc gtaaatgtaa ttttaaagaa
     4981 aaagataagt taaaaaaaga tgtattagca agagttggtc taactcatat tcatctagaa
     5041 caaaagatat atgaattgtc tggcggtgaa gcataacgtg ttgctttagc gaaaatcatt
     5101 cttaaaaatc caccattaat actcgcggat gagctgactg catcactcga tccgacgact
     5161 tcacaaggaa ttatgaaatt attattagat atgaaaaatg aaaatcgtct aatcatcatt
     5221 gcaactcata atcccgatat ttggaatcaa gcagatgaag ttataaattt aaatcaatta
     5281 tagttacagc caatatatat tttctatatt ttaaagttat tttatctgaa tccgtaaaag
     5341 cagttcaatc ttgtactgac ccccaaaagt tagacaatta atttatccga aggatttagt
     5401 tctgtattgc acaggactaa gtccttttag ttttatctta attcgtttgt tgttgtaata
     5461 atcaatatag tctacaatag cttgttccaa ttgattaagc gactgaaatg tcttctcata
     5521 accataaaac atttcggatt tcaaaatgcc aaagaaggac tccatcatgc cattgtctgg
     5581 gctgtttccc ttgcgtgaca tggatgcttg aattccctta ctctctagga accgatgata
     5641 agaatcgtgt tggtattgcc agccttgatc gctatggaga atggtattct cataatgttt
     5701 ctctgtaaag gcctggttta acatagcttt cccttgttct aagtttggtg aagttgaaag
     5761 attataggcg ataatttcgc tgttaaagcc atctaaaact ggcgataaat agagcttttg
     5821 actgcttgct ggaatggcaa actctgtcac atccgtatag cacttttcca ttggtctcga
     5881 tgcttcgaac tggcgttgaa tgagattctc tgctttcttg ccaatctctc cttggtagga
     5941 ggaatacttt cgtttccgac gaattcgagc tgttaaacca agaactttca tcagacgttg
     6001 aactttctta tgattcacca caaaaccacg atttcttagt tcaagagtaa ctctacgata
     6061 gccataattt cctttgtgct cagtaaaaat agcttgaatt tcagctttaa gatctttatc
     6121 tttgtcaagc ccacctagtc ccttcaactg atagtagtaa gtcgagcgag ctaaacgtgc
     6181 tgtttcaaga agtaaatcta attgaaatcc tcctgaagcc atttctctaa ctatctctgc
     6241 ctttctcgct ctagggcttc gtccctgtct tccagctctt ttaacttttt taagtaagcc
     6301 acctcggtac gtaagcgttc attctcctct tgaagtcgct ctagttctgt catttcttcc
     6361 caagttttct tacgtttacg tcccatttta ggtactctct ctcttgtttt ctcaacaata
     6421 gtatacccgt ttttcttgta ttgcgccagc caatttggaa gcataccacg atttgggaga
     6481 gcatatttga gagaaactct atcttgagac cagttttcat gtaaaacttt atcaatcatt
     6541 tcttgtttta gttctggaga atagtatcga tttttccctt ttttgatgaa ctctattccg
     6601 taacgatcaa tcaatttaat catgtaccta agattagaat tgtttatctc aaatttattt
     6661 gaaatcttct ctaagctata tccttgcttt cttagttcat agatctgaac tttatcctca
     6721 taactcaatt tcataataaa acaccccaaa aagtagattt tttctgtcta acttttgggg
     6781 tgcagttcat cttgtactgc ttttttcttt tacgacttac gctgtttggc ttcatgagca
     6841 agccctcaaa gtgaactaat aacaaatcat gagaagtcaa agtgatgaaa tttctgtaac
     6901 agaagtagag cgaattgctg aaccattaaa tgagtatatc tcgaagtaga agcgtctatt
     6961 ttgactttta gtctgataga atggtagttt gaaaatgtaa atgatagcta ctgttcataa
     7021 aacataaaag gtaagtacgg tgttgtgaga agagctagaa attagcactt acctgattat
     7081 tccaataacc tcaaagatgt gataaaaatt tcaactactc ttatctataa taaagctacc
     7141 tgttctttga aaattgaatt cactccgtct tgattagcgt gcctgtgtaa gtagggactg
     7201 agagtatttc cctgtgaagg gcaactggca caagacgtgt gtgagaattt tctaacagac
     7261 acggagttta tcgtttccag actcaaacga tgcgacaaac tagataaagg agttaatcat
     7321 gaaggtagta aacttgtatg atttgaaaca aatgggaaat aaaggtggtt gtaccatcca
     7381 attgattcat cactttcctt ttggtatggg cttaggacat ctcaaaaaag actacattga
     7441 atttaaacgt gttggtatct ttgatgggaa agcagtagaa gttactcttc gagaacctta
     7501 ttcgagagat ctacttcagg ttgtcaagtc aataaagtaa ctgacaccac gagtataatt
     7561 attagaaacg tggaatctta ttaaatttta taataaatat attaaatgaa aaattattag
     7621 atataaactt atgtaataaa acattgagga aataataaaa atctatgggt aatgttctga
     7681 aagtactttt aggttaggag agaaatataa tgatttttga aaattgattc aaaaaatagc
     7741 gaattgtaga aaacgcttaa caaatggtgt ataatagact tccagcgaaa caaaatatgc
     7801 tacaataaac ctatgaatta taaagcaacc ttatactcat ctgtcttcac aaagcattct
     7861 agtccatctc cgattaacga tggactttat catctccttc tccagtcctt gtatgacatc
     7921 ttccaaagtt cgaaaggctt tattcttaaa tccacgttta cgaatctctt tccacactta
     7981 ttcaatgggg ttcatctctg gtgtgtatgg aggaataaat gcaaagccaa tattagtcgg
     8041 aatctttaag gcacttgatt tatgccatat agcattgtcc ataacgagta aaatataatc
     8101 atctggataa gcttgtgaaa gtttggctga cagtggttat caagggctca tgaagatata
     8161 tcctcaagca caaactccac gtaaatccag caaactcaag ccgctaacag ttgaagataa
     8221 agcctataac catgcgctat ctaaggagag aagcaaggtt gagaacatct ttgccaaagt
     8281 aaaaacgttt aaaatgtttt caacaaccta tcgaaatcat cgtaaacgtt ttggattacg
     8341 aatgaatttg agtgctggta ttatcaatca tgaactagga ttctagtttt gcaggaagtc
     8401 tattatcaaa aataccatca ggattatata agattgatac aggaaaagtt ttatttgatg
     8461 gtgtaaatat taatcaaata gataaaaaaa tattaagtca aaatttagga gtagttccac
     8521 aggattcgtt tttattgaac agaagtattc ttgataacat aactttaaag cacgaagtta
     8581 cttcacaaaa gatagaggaa gtttgtaaag cagttcaaat ctatgatgaa atcatggcta
     8641 tgccgatgaa atttaatact atcatctcag agatgggttc aaatatttca ggtggtcaaa
     8701 gacaacggat agcactggca cgtgcattaa taaataatcc tagtattgta attttagatg
     8761 aagcaactag tgctttagac actattaatg aggaaagaat aacaaagtat ataaaaagtc
     8821 agggctgtac tcaaataatt gtagctcata gattgtcaac gattaaggat gcggatatta
     8881 ttgttgtaat gaaaggtggt aagattgttg agtcaggaaa tcataagtac ttaatggatc
     8941 ttggtggaga gtactacagc ttatatacaa aaaggaaatg aggtgtaaag aaaatgaaga
     9001 aagaaaatga atatgtaatt ttaacaacag cctcactagg ggtgatgatt ggaatagtgt
     9061 ttgcaatttt tttagatttt ccagttgaat atggtatttc tttaggctta ttgaatggaa
     9121 tagtattggg ttcgctgatt gtttacaaaa acaataagaa ttaagcataa ttttttgctg
     9181 taaactaagg agtagagatg gctatagttg aaattataaa tctaacaaaa agctttaaag
     9241 atattgaagt tattcataac acttaaataa tagagcaact acagtagtag cttaaaaaca
     9301 tgattaaatc gctattctta ggagtagcgg tttttctttt tgtttaatac tctttgaaaa
     9361 tctcttcaaa ccacgtcagc tttgccttgc cgtactcaag tacagcctgc gactcgcttc
     9421 ctagtttgct ttttgatttt cattgagtat aaaaagggtt aagtaagtat agtaaattga
     9481 aataagatat gaacaaatcg attagaaaag tcaaattaat ttctagaaat atgttagaaa
     9541 ttggtttgaa ttccgcaatc aatttgttca gtttttattt catttaatta gaatttccca
     9601 actgt
//
LOCUS       DAVLXH010000069         9603 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00028199
            SAMN33607166-rid17955573.denovo.070, whole genome shotgun sequence.
ACCESSION   DAVLXH010000069 DAVLXH010000000
VERSION     DAVLXH010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607166
            Sequence Read Archive: SRR23725544
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9603)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9603)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721421.1
            Genome Coverage       :: 115x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:42:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,210
            CDSs (total)                      :: 2,161
            Genes (coding)                    :: 2,023
            CDSs (with protein)               :: 2,023
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 73 of 138
            Pseudo Genes (incomplete)         :: 60 of 138
            Pseudo Genes (internal stop)      :: 40 of 138
            Pseudo Genes (multiple problems)  :: 31 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9603
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607166-rid17955573.denovo.070"
                     /strain="AUSMDU00028199"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1349"
     gene            453..1496
                     /locus_tag="VYO11_001911"
     CDS             453..1496
                     /locus_tag="VYO11_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00341 family protein"
                     /protein_id="HEV1596412.1"
                     /translation="MTNNKLYSLIEFRNKIYEELELSRSDLAILLCAMLIASIGLNMD
                     STPVIIGAMLISPLMTPILGVGLSLAIFDFKLLRKSFKILAIQILASLIASTLYFYLS
                     PISYASSEIVARTSPTIWDVLIAFVGGIAGIIGARKKETNNIVPGVAIATALMPPLCT
                     VGYAIASANLKFIIGSSYLFLINCSFIVIATYIGVRLMMVKKHYFKDNEEDSKMRRIL
                     LLVAVLLMIPSFISATTLVRETLKKESLKKFISEQFQGYNILKKTYSKKTHTLKLTIS
                     GNYLTEEELDMISSKRGDYGLSDVSVQVSQLSDSEQLSKEELVEYFFQYIKDKEAKEK
                     EKANKFYTESEEQ"
     gene            1663..3750
                     /gene="topA"
                     /locus_tag="VYO11_001912"
     CDS             1663..3750
                     /gene="topA"
                     /locus_tag="VYO11_001912"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HEV1596413.1"
                     /translation="MATATKKKKSTVKKNLVIVESPAKAKTIEKYLGRNYKVLASVGH
                     IRDLKKSSMSVDIENNYEPQYINIRGKGPLINDLKKEAKKANKVFLASDPDREGEAIS
                     WHLAHILNLDENDANRVVFNEITKDAVKNAFKEPRKIDMDLVDAQQARRILDRLVGYS
                     ISPILWKKVKKGLSAGRVQSIALKLIIDRENEINAFQPEEYWTVDAVFKKGTKQFHAS
                     FYGVDGKKMKLTSNDEVKEVLSRLTSKDFSVDQVDKKERKRNAPLPYTTSSMQMDAAN
                     KINFRTRKTMMVAQQLYEGINIGSGVQGLITYMRTDSTRISPVAQNEVASFITDRFGS
                     KYSKHGSKVKNASGAQDAHEAIRPSSVFNTPESIAKYLDKDQLKLYTLIWNRFVASQM
                     TAAVFDTMAVKLSQKGVQFAANGSQVKFDGYLAIYNDSDKNKMLPDMVVGDVVKQVNS
                     KPEQHFTQPPARYSEATLIKTLEENGVGRPSTYAPTIETIQKRYYVRLAAKRFEPTEL
                     GEIVNKLIVEYFPDIVNVTFTAEMEGKLDDVEVGKEQWRRVIDAFYKPFSKEVAKAEE
                     EMEKIQIKDEPAGFDCEVCGSPMVIKLGRFGKFYACSNFPDCRHTQAIVKEIGVECPS
                     CHQGQIIERKTKRNRLFYGCNRYPECEFTSWDKPVGRDCPKCGNFLMEKKVRGGGKQV
                     VCSKGDYEEEKIK"
     gene            3856..4215
                     /locus_tag="VYO11_001913"
     CDS             3856..4215
                     /locus_tag="VYO11_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaN family protein"
                     /protein_id="HEV1596414.1"
                     /translation="MRLIYLIIGFLSLTLAIVGVVLPLLPTTPFLLLSIACFSRSSKR
                     FEDWLYHTKLYQTYVADFRETKSITRERKKKIIVSIYILMGISIYFAPLLPVKIGLGA
                     LTIFITYYLFKVIPDKE"
     gene            4308..4940
                     /locus_tag="VYO11_001914"
     CDS             4308..4940
                     /locus_tag="VYO11_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HEV1596415.1"
                     /translation="MIYEFCAENVTLLEKAMQAGARRIELCDNLAVGGTTPSYGVTKA
                     AVELAANYDTTIMTMIRPRGGDFVYNDLEIAIMLEDIRLTAQAGSQGVVFGTLTADKK
                     LDKPNLEKLIAASKGMEIVFHMAFDELSDEDQLEAIDWLSQAGVTRILTRAGVSGDSL
                     EKRFVHYHRILEYAKGKIEILPGGGIDLENRQTFIDQVGVTQLHGTKVVF"
     gene            4984..5640
                     /locus_tag="VYO11_001915"
     CDS             4984..5640
                     /locus_tag="VYO11_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HEV1596416.1"
                     /translation="MFEIFKSYQFNQEKAHDYGFIENSEVWTYSCQILQGDFVMTVSI
                     TADNVNFQVFDQETGDLYPQVHMESMTGSFVASVREACLEILYQIRKACFDVQDFICH
                     QTKRIMTQVQEKYGNQLEYLWEKSPDTAVLRHEGNQKWYAVLMKISWNKLEKGREGQV
                     EAVNLKHDQVANLLSQKGIYPAFHMSKRYWISVSLDDTLSDEEVLELIEKSWNLTSKK
                     "
     gene            5659..6753
                     /locus_tag="VYO11_001916"
     CDS             5659..6753
                     /locus_tag="VYO11_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001010962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-isopropylmalate synthase"
                     /protein_id="HEV1596417.1"
                     /translation="MNFQLAKYSLLKKFSENIEFTAPEEYGAIFKYLIENVKTDRQII
                     YSPHCHDDLGMAVANSLAAVKNGAGRVEGTINGIRERAGNAALEEIAVALNIRQDYYQ
                     VETSIVLNETINTSEMVSRFSGIPVPKNKAVVGGNTFSHESGIHQDGVLKNPLTYEII
                     TPELVGVKIPLGKLSGRHAFVEKLRELALDFTEEDIKPLFAKFKALVDKKQEITDADI
                     RALVAGTMVENPEGFHFDDLQLQTHADNDIEALVSLANMDGEKVEFNATGQGSVEAIF
                     NAIDKFFNQSVRLVSYTIDAVTDGIDTQDRVLVTVENRDTETIFNAAGLDFDVLKASA
                     IVYINANTFVQKENAGEMGRSVSYHDMPSV"
     gene            6765..7802
                     /gene="leuB"
                     /locus_tag="VYO11_001917"
     CDS             6765..7802
                     /gene="leuB"
                     /locus_tag="VYO11_001917"
                     /EC_number="1.1.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydrogenase"
                     /protein_id="HEV1596418.1"
                     /translation="MAKKIVALAGDGIGPEIMEVGLEVLEALAEKTGFDYEIDRRPFG
                     GADIDAAWPPLPDETLKASREADAILLAAIGSPQYDGAVVRPEQGLMALRKELNIYAN
                     IRPVKIFDSLKHLSPLKLERIAGVDFVVVRELTGGIYFGDHILEERNARDINDYSYEE
                     VERIIRKAFEIARNRRKIVTSIDKQNVLATSKLWRKVAEEVAQDFPDVTLEHQLVDSA
                     AMLMITNPAKFDVIVTENLFGDILSDESSVLSGTLGVMPSASHSENGPSLYEPIHGSA
                     PDIAGQGIANPISMILSVVMMLRDSFGRYEDAERIKRAVETSLAAGILTRDIGGQAST
                     KEMTEAIIARL"
     gene            7799..8068
                     /locus_tag="VYO11_001918"
     CDS             7799..8068
                     /locus_tag="VYO11_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HEV1596419.1"
                     /translation="MKLDEKITLVLLIWNVIIFLIYGIDKFKARRRAWRIQEKILLIL
                     ALTCGGFGAWLAGITFHHKTRKWYFKTVWFLGMVTTLVALYFIWR"
     gene            8072..8431
                     /locus_tag="VYO11_001919"
     CDS             8072..8431
                     /locus_tag="VYO11_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase small subunit"
                     /protein_id="HEV1596420.1"
                     /translation="MAGSSREHAAWALANYGFKVVIAGTFGDIHYNNELNNGMLPIVQ
                     PREVREKLAQLKPTDHVTVDLEQQKIISPVEEFTFEIDSEWKHKLLNSLDDIGITLQY
                     EELIAAYEKQRPAYWQD"
     gene            8650..8793
                     /locus_tag="VYO11_001920"
     CDS             8650..8793
                     /locus_tag="VYO11_001920"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1596421.1"
                     /translation="MTSDKAGLERKFAAKERKRNKPGVVLCGSMDELCALAQLNPEIE
                     AFY"
     gene            8812..9066
                     /locus_tag="VYO11_001921"
     CDS             8812..9066
                     /locus_tag="VYO11_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1596422.1"
                     /translation="MLLGCILPWKPEAFEKLKAYGDGREELMTDVRGTSCFVIKFGKA
                     GEQLAAKLWEEGKMVYASYASMTKRLKLAMRARCNGVYGR"
     gene            9056..9217
                     /locus_tag="VYO11_001922"
     CDS             9056..9217
                     /locus_tag="VYO11_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1596423.1"
                     /translation="MVDKDGKLIPEQGGARSTSPAPVVIRKGLDIDKIMMHLSDTFNS
                     WDYRQREYY"
     gene            9382..>9603
                     /locus_tag="VYO11_001923"
     CDS             9382..>9603
                     /locus_tag="VYO11_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1596424.1"
                     /translation="MNKRKVSLEDFYKWYSLNKEELLNKATVGEKFNDKLKEEFLQEW
                     PLDRILTMSIDEYVIGKGQQNKSLCYALEK"
BASE COUNT         2995 a         1653 c         2133 g         2822 t
ORIGIN      
        1 ttagtgtaat tgagaaagga gaaatgattg tgattgatgt tggctaggtt atgttcaatg
       61 attcctaccg tctcaaatct tgtcagtaag gaaaaataaa ttcttcaaaa gtagagatta
      121 caaggcttgt ttaagaaaga attcaaagac cttgacaaat aaaaataaaa tggttattat
      181 aagaaatggt ctaaaataga tgatgatact tttcgaaaat ctttttacgt cagctcagct
      241 ttgccttgct gtgttttgag caagctacgg ttagcttccg agtttgattt tcatttacta
      301 gaaatgaaac tgatgagaga tatcagtaga catttgagtc aggatattat ggaaaatgat
      361 aaaaagagct tgtgagattg gcatatcaga ctactaaagt attgagtttg ttaggatttt
      421 agcgactagt tagctgggaa aggaagatat ttgtgacaaa taataaactg tattcgttga
      481 tagaatttag aaataaaata tatgaagaat tagaactttc cagaagtgat ttagcgattt
      541 tactatgtgc catgcttatc gcctctatcg gattaaatat ggattcgact cccgtgatta
      601 ttggagccat gttaatctct cctttgatga cacctattct gggagtgggg ctctctctag
      661 ctatatttga ttttaaattg ttaagaaaat cttttaaaat attagctatt caaattcttg
      721 ccagtctaat agcttcaaca ctttattttt atctttctcc catttcgtat gctagttcgg
      781 agattgttgc tagaacctct ccgactattt gggatgttct cattgctttt gtaggaggga
      841 tagcaggtat tattggtgct aggaaaaaag agaccaataa tattgttcct ggtgttgcta
      901 ttgcaaccgc cttgatgcct cctctttgta cagtaggtta tgctattgct tctgctaatc
      961 taaaatttat cataggctcc tcttacctat tcctcatcaa ttgtagcttt attgtcattg
     1021 cgacttatat aggtgttagg ttgatgatgg ttaagaaaca ttattttaaa gataatgaag
     1081 aagactctaa aatgcgtagg attttgcttc tagttgctgt tttgctgatg attccgagtt
     1141 tcatctctgc aacgacttta gtgagagaaa cgttgaaaaa agagtccctt aagaaattta
     1201 tatcagagca gtttcagggg tataatattt tgaaaaaaac ctattctaaa aagactcata
     1261 ccctaaagct aaccatttca ggaaattatt tgacagaaga agaactcgat atgatttcaa
     1321 gtaagagagg tgactatggt ttaagtgatg tttctgttca agtttcacaa ttgtctgatt
     1381 cagaacaact tagtaaggaa gagctggtgg agtatttctt ccagtatatc aaggataagg
     1441 aagcaaaaga aaaggaaaaa gctaataagt tttatacaga gtctgaggag caataatttc
     1501 ttgagaatag ctggtttttc tcgtgagtct tctatgtata tcaaaggaag actgaggttt
     1561 taagtataaa acttttcttc tattatagta gctaagtctt gacagggttc aaaaaatggt
     1621 ttacacttta taaagtttat tactttgaaa aggtgtgata ctgtggctac ggcaacaaaa
     1681 aagaaaaaat caacagttaa aaaaaatcta gtcatcgtgg agtcgcctgc taaggccaag
     1741 acgattgaaa aatatctagg cagaaactac aaggttttag ccagtgtcgg gcatatccgt
     1801 gatttgaaga aatccagtat gtccgtcgat attgaaaata attatgaacc gcaatatatt
     1861 aatatccgag gaaaaggccc tcttatcaat gacttgaaaa aagaagctaa aaaagctaat
     1921 aaagtttttc tcgcgagtga cccggaccgt gaaggagaag cgatttcttg gcatttggcc
     1981 catattctca acttggatga aaatgatgcc aaccgtgtgg tcttcaatga aatcaccaag
     2041 gatgcagtca aaaatgcttt taaagaacct cgtaagatcg atatggactt ggtcgatgcc
     2101 caacaagctc gtcggatctt ggaccgcttg gtagggtatt cgatttcgcc tattttgtgg
     2161 aagaaggtca agaagggctt gtcagcaggt cgcgttcagt ccattgccct taaactcatc
     2221 attgaccgtg aaaatgaaat caatgccttc cagccagaag aatactggac agttgatgct
     2281 gtctttaaaa agggaaccaa acaatttcat gcttccttct atggagtaga tggtaaaaag
     2341 atgaaactga ccagcaatga cgaagtcaag gaagtcttgt ctcgtctgac gagtaaagac
     2401 ttttcagtag atcaggtgga taagaaagag cgcaagcgca atgctccttt accctatacc
     2461 acttcatcta tgcagatgga tgctgccaat aaaatcaatt tccgtactcg aaaaaccatg
     2521 atggttgccc aacagctcta tgaaggaatt aatatcggtt ctggtgttca aggtttgatt
     2581 acctatatgc gtaccgattc gactcgtatc agtcctgtag cgcaaaatga ggtggcaagc
     2641 ttcattacgg atcgttttgg tagtaagtat tctaagcacg gtagcaaggt caaaaacgca
     2701 tcaggtgctc aggatgccca tgaggctatt cgtccgtcaa gtgtctttaa tacaccagaa
     2761 agcatcgcta agtatctgga caaggatcag ctcaagctat atacccttat ctggaatcgt
     2821 tttgtggcta gccagatgac agcggccgtt tttgatacca tggctgttaa attgtctcaa
     2881 aaaggggttc aatttgctgc caatggtagt caggttaagt ttgatggtta tcttgccatt
     2941 tataatgatt ctgacaagaa taagatgtta ccggacatgg ttgttggaga tgtggtcaaa
     3001 caggtcaata gcaaaccaga gcaacatttc acccaaccgc ctgcccgtta ttctgaagca
     3061 acactgatta aaaccttaga ggaaaatggg gttggacgtc catcaaccta cgcgccaacc
     3121 attgaaacca ttcagaaacg ttattatgtt cgcctggcag ccaaacgttt tgaaccgaca
     3181 gagttgggag aaattgtcaa taagctcatc gttgaatatt tcccagatat cgtaaacgtg
     3241 accttcacag ctgaaatgga aggtaaactg gatgatgtcg aagttggaaa agagcagtgg
     3301 cgacgggtca ttgatgcctt ttacaaacca ttctctaaag aagttgccaa ggctgaagaa
     3361 gaaatggaaa aaatccagat taaggatgaa ccagctggat ttgactgtga agtgtgtggc
     3421 agtccaatgg tcattaaact tggtcgtttt ggtaaattct acgcttgtag caatttccca
     3481 gattgccgtc atacccaagc aatcgtgaaa gagattggtg ttgagtgtcc aagctgtcat
     3541 cagggacaaa ttattgagcg aaaaaccaag cgtaatcgcc tcttctatgg ttgcaatcgc
     3601 tatccagaat gtgaatttac ctcttgggac aagcctgttg gtcgtgactg tccaaaatgt
     3661 ggcaacttcc tcatggagaa aaaagtccgt ggtggtggca agcaggttgt ttgtagcaaa
     3721 ggcgactacg aggaagaaaa gattaaataa gaggaggggc ccgaaagtaa atttcaggct
     3781 ccttttggtt agaacttgac aaaatacatc attttatgcg aaactagaag aagattattt
     3841 taactaggag aagttatgcg tcttatctat ctgataattg gttttttatc actgaccttg
     3901 gctattgttg gggttgtttt acccttgttg ccgacaacgc ctttcctttt gttgtctatt
     3961 gcttgtttct ccagaagttc caagcgtttc gaagactggc tttatcatac caagctctat
     4021 caaacatatg tagctgattt tcgcgagact aagtctatta cgcgtgaacg aaagaaaaaa
     4081 atcatcgtat ccatttacat tttgatgggg atttctattt attttgcccc tctcttacca
     4141 gtcaaaatcg gtctgggtgc tttgaccatc tttatcactt attatctttt caaggtcatt
     4201 ccagacaaag aatagttaaa acagtagtta tttgccttga taaaattgaa agcatattca
     4261 taacaatatg atataataaa tttgaagtaa tattcaagga gaatcaaatg atttacgaat
     4321 tttgtgctga aaatgtgact ttacttgaaa aagcgatgca ggctggagct cgtcggattg
     4381 aactctgtga taatctagca gttggtggga caacacccag ctatggagtg actaaggcag
     4441 cggttgaact ggcagctaac tacgatacaa ccatcatgac catgattcgg ccacgtggtg
     4501 gtgactttgt ctataatgac ctagaaattg ctatcatgct agaagacatt cgtttgactg
     4561 ctcaggctgg aagtcaaggg gttgtatttg gaactttaac tgctgataaa aagttggata
     4621 agcctaatct ggaaaagtta attgctgcat caaaaggaat ggaaattgtc tttcacatgg
     4681 cctttgatga actaagtgat gaagatcaac tggaagctat tgactggctc agtcaagccg
     4741 gtgtcactcg tatcctaact cgtgctggtg tgtctggcga ctccttagaa aaacgttttg
     4801 ttcactatca cagaattttg gagtacgcta aaggtaaaat tgaaattcta ccaggtgggg
     4861 ggattgacct tgaaaaccgt caaaccttta tcgaccaggt gggggtaaca caattgcatg
     4921 gtactaaggt tgttttttaa aaaatagaaa ggaactgcta gctttgggta gcagttttca
     4981 cttatgtttg aaatttttaa atcctatcaa tttaatcaag aaaaggctca tgattatggt
     5041 tttatagaaa atagcgaagt ctggacatat agttgccaga ttttgcaagg tgactttgtc
     5101 atgactgtgt ccatcactgc tgataatgtg aactttcaag tctttgacca agagactggt
     5161 gacctctatc ctcaagttca tatggaaagt atgacaggaa gttttgttgc aagtgtccgt
     5221 gaggcttgtc tggagattct ttaccagatt cggaaggctt gttttgatgt gcaagatttt
     5281 atctgtcatc agactaagcg tatcatgact caagttcagg aaaagtatgg aaaccagttg
     5341 gagtatctgt gggaaaaatc gcctgataca gctgtattgc gccatgaagg caatcaaaag
     5401 tggtatgccg tcttgatgaa aatctcttgg aataagctgg aaaagggcag agaaggacaa
     5461 gtggaagcag tcaacctcaa gcatgaccaa gtagctaatt tgctttcaca aaaggggatt
     5521 tatccagcct tccatatgag caagcgctac tggattagtg tgtcccttga tgatacttta
     5581 tcagatgaag aagtactgga attgatagaa aaaagttgga acttaacctc taaaaaatga
     5641 aatattttaa taattttcat gaactttcaa ttagctaaat attctttact gaagaaattt
     5701 tcagaaaata tagaatttac cgcgccagag gaatatggtg ccatcttcaa atacctgatt
     5761 gagaatgtca agacggatcg tcagatcatc tattcgcctc actgtcatga tgacctcgga
     5821 atggcagtgg caaatagtct tgctgctgtc aagaatggtg caggacgtgt tgaagggact
     5881 atcaatggta ttagggagcg agctggaaat gctgctttgg aagaaattgc agtggctctc
     5941 aatattcgcc aagattacta ccaagtagaa accagtattg tcctaaatga gaccatcaat
     6001 acgtcagaaa tggtttctcg cttctctggt attccagttc ctaaaaacaa agccgtcgtt
     6061 ggtggcaata ccttctccca cgaatctggt attcaccaag atggagtcct taaaaatcct
     6121 ctcacttatg agatcatcac acctgaattg gttggtgtta agattccgct tggaaaatta
     6181 tctggtcgcc atgcttttgt tgagaaactg agagaattgg ccctagattt tacagaagag
     6241 gatatcaaac cactctttgc taagttcaag gcactggtcg ataagaagca agaaatcaca
     6301 gatgcagata ttcgagcttt ggtagctgga accatggttg aaaatccaga aggcttccac
     6361 tttgatgatt tacaacttca aactcatgca gataatgaca ttgaagcgct cgttagccta
     6421 gccaatatgg atggtgagaa agtcgaattt aatgcgacag ggcaaggttc cgttgaagca
     6481 atctttaatg ctatcgataa gttctttaac caatctgttc gtttggtgtc ctacactatc
     6541 gatgcggtaa cagatggaat cgatacccag gatcgggttt tggtcactgt tgaaaacaga
     6601 gatacagaaa ccatctttaa tgcagcaggg cttgattttg atgtgttgaa ggcttctgct
     6661 attgtctata taaacgctaa tacctttgtt caaaaagaga atgcaggtga gatgggacgc
     6721 agtgtttctt accacgatat gcctagtgtg taaaggagaa ggctatggca aagaaaatag
     6781 tagctctagc aggagacgga attggcccag aaatcatgga ggttggttta gaagttctgg
     6841 aggctctagc tgaaaaaaca ggttttgact atgagattga cagacgaccg ttcggaggtg
     6901 cagatattga tgcagcatgg cctcccttac ctgatgaaac ccttaaggca agtagggaag
     6961 cagatgctat cctactagca gctatcggta gtcctcagta tgatggagca gtggttcgcc
     7021 ctgaacaagg cctgatggct ctccgtaagg aactcaatat ttacgctaat attcgtcctg
     7081 taaaaatctt tgacagtctc aagcatttgt caccactcaa actggaacga attgctggtg
     7141 tagactttgt cgtggtgcgt gaattgacag gcgggattta ctttggagat catattcttg
     7201 aagagcgcaa tgcgcgtgat atcaacgact atagctatga ggaagtggag cggattattc
     7261 gcaaagcctt tgaaattgca agaaatcgca gaaaaatcgt tactagtatc gataagcaaa
     7321 atgttctagc gacctcaaaa ctctggcgga aggtagctga ggaagtcgca caggatttcc
     7381 cagatgtaac cttggaacat cagctggtag actcagctgc tatgcttatg attaccaatc
     7441 ctgctaagtt tgatgttatt gtaacggaga atctttttgg agatatttta tctgatgaat
     7501 caagcgtctt atctggtaca cttggggtta tgccatcagc cagtcattct gaaaatggac
     7561 caagtctcta tgaacctatt cacggttcag cacctgatat tgcaggtcaa ggaattgcca
     7621 atcctatttc catgatttta tcagttgtca tgatgttgag agatagtttc ggacgttatg
     7681 aggatgcaga gcgtatcaaa cgtgctgttg agacaagtct ggcggcagga attttaacga
     7741 gagatatagg aggtcaggct tcaacaaagg aaatgacgga agctattatt gcaaggttat
     7801 gaagttagac gaaaaaatta ctctagtcct tttgatttgg aatgtcatca ttttcttgat
     7861 ttatggcatt gacaaattca aggcaagaag aagagcttgg cgcatccaag agaaaatctt
     7921 actcatttta gcccttactt gtggtggttt tggggcctgg ttagctggaa tcacttttca
     7981 ccacaagact cgaaaatggt actttaaaac agtttggttt cttgggatgg tgactacact
     8041 agtagcctta tattttattt ggaggtaatg gatggcaggg tcttcgaggg aacacgctgc
     8101 ttgggctcta gcgaactatg gttttaaggt cgtgattgca ggaactttcg gtgacattca
     8161 ttacaataat gaactcaata atggcatgtt gccaatcgtt cagcctagag aggttagaga
     8221 gaaactagcc cagctaaaac caaccgacca tgtaactgtg gacttggaac aacaaaaaat
     8281 catctcacca gttgaagaat tcaccttcga gatagatagc gagtggaaac ataaactcct
     8341 aaatagtttg gatgatatcg gtattacctt gcagtatgaa gagttgattg ctgcttatga
     8401 aaaacaacga ccagcctact ggcaggatta gaaaaaatag aaaaggaaat atagtaaact
     8461 gaaataagat gtaaacaaat gaattagagc ttaacatcca tttccagcaa ttttttagaa
     8521 actacagtgg actattctgg attcaacaca ttataaaatt atgacaaaac acattcacaa
     8581 gaaggctacg acattttaaa aggtgagggt ggatgtatcg tttgccctac taaagttggt
     8641 tacattatca tgaccagtga taaggcagga cttgagcgta agttcgcagc caaagaacgt
     8701 aagcgtaaca aaccaggtgt tgttctctgc ggtagcatgg atgaactttg cgctttagcg
     8761 caactcaacc cagaaattga agcattctac taaaaacatt gggatgaaga tattcttctt
     8821 ggttgtatcc ttccttggaa accagaagcc tttgaaaaac tcaaagcata cggggatggc
     8881 cgtgaagaac ttatgactga tgtacgtggt actagctgtt ttgttatcaa gtttggaaaa
     8941 gcaggtgaac aattggctgc caagctttgg gaagaaggta aaatggtcta cgcctcatat
     9001 gcttcaatga caaaacgatt gaaactcgct atgagagcaa ggtgtaatgg tgtctatggt
     9061 cgataaggac ggcaaactca tcccagaaca aggaggagca cgttcaacct caccagcacc
     9121 agttgtgatc cgtaaagggc ttgacattga taaaatcatg atgcacctgt cagacacctt
     9181 taactcatgg gattaccgtc agagagagta ttattaggat aaaaaagaag tctagtgtta
     9241 tgagatatta aagctcctaa cactgggctt tttgtttaga atttcttttc tttttctata
     9301 ggatatggta ttctatgtag aaaatatatg ttaataagta atgccaatat ttaaacatca
     9361 ttagtaaaag gagttagatt gatgaataaa agaaaagtta gtttagaaga tttttataaa
     9421 tggtatagtc taaataaaga agagttatta aataaggcaa ctgttggtga aaagtttaat
     9481 gataaattaa aagaagagtt tctccaggaa tggcctttgg ataggatttt aacaatgtca
     9541 atcgatgaat atgtaatagg aaagggacag caaaataagt ctttatgcta cgctcttgag
     9601 aag
//
LOCUS       DAVLXH010000070         9598 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00028199
            SAMN33607166-rid17955573.denovo.071, whole genome shotgun sequence.
ACCESSION   DAVLXH010000070 DAVLXH010000000
VERSION     DAVLXH010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607166
            Sequence Read Archive: SRR23725544
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9598)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9598)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721421.1
            Genome Coverage       :: 115x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:42:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,210
            CDSs (total)                      :: 2,161
            Genes (coding)                    :: 2,023
            CDSs (with protein)               :: 2,023
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 73 of 138
            Pseudo Genes (incomplete)         :: 60 of 138
            Pseudo Genes (internal stop)      :: 40 of 138
            Pseudo Genes (multiple problems)  :: 31 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9598
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607166-rid17955573.denovo.071"
                     /strain="AUSMDU00028199"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1349"
     gene            complement(<1..603)
                     /locus_tag="VYO11_001924"
     CDS             complement(<1..603)
                     /locus_tag="VYO11_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000917571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEV1596425.1"
                     /translation="MLKQEKLTKILEIVNSKGTITVKQIMDEIAVSDMTARRYLQELA
                     DKDLLIRVHGGAEKLRTNSLLTNERSNIEKQALQTAEKQEIAHFAGSLVEERETIFIG
                     PGTTLEFFARELPIDNIRVVTNSLPVFLILSERKLTDLILIGGNYRDITGAFVGTLTL
                     QNLSNLQFSKAFVSCNGIQNGALATFSEEEGEAQRIALNNS"
     gene            complement(785..1747)
                     /gene="nrdF"
                     /locus_tag="VYO11_001925"
     CDS             complement(785..1747)
                     /gene="nrdF"
                     /locus_tag="VYO11_001925"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HEV1596426.1"
                     /translation="METYYKAINWNAIEDVIDKSTWEKLTEQFWLDTRIPLSNDLDDW
                     RKLSNKEKDLVGKVFGGLTLLDTMQSETGVQALRADIRTPHEEAVFNNIQFMESVHAK
                     SYSSIFSTLNTKAEIEEIFEWTNTNPYLQKKAEIVNEIYLNGSPLEKKVASVFLETFL
                     FYSGFFTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEEEQEKLK
                     EWMYDLLYTLYENEEGYTESLYDGVGWTEEVKTFLRYNANKALMNMGQDPLFPDSAED
                     VNPIVMNGISTGTSNHDFFSQVGNGYLLGEVEAMQDDDYNYGLD"
     gene            complement(1935..4094)
                     /gene="nrdE"
                     /locus_tag="VYO11_001926"
     CDS             complement(1935..4094)
                     /gene="nrdE"
                     /locus_tag="VYO11_001926"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000523276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HEV1596427.1"
                     /translation="MGLKHLEDVTYFRLNNEINRPVNGQIMLHKDKEALDAFFKENVV
                     PNTMVFDSIKDKINYLIEHNYIETAFIKKYRPEFLEELAQFIKDQNFQFKSFMAAYKF
                     YNQYALKTNDGEYYLENMEDRVFFNALYFADGNEAVAIDIANEIIHQRYQPATPSFLN
                     AGRARRGELVSCFLIQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSTKKENADEKVR
                     VKTLSLGVVVPDKFYELARKNEEMYLFSPYSVEKEYGVPFNYIDITEKYDELVANPNI
                     RKTKIKARDLETEISKLQQESGYPYVVNIDTANRANPVDGKIIMSNLCSEILQVQEPS
                     LINDAQEFLQMGTDVSCNLGSTNVVNMMTSPDFGRSIRAMVRALTFVTDSSHIVAVPT
                     IDHGNSQAHTFGLGAMGLHSYLAQQLIEYGSPESVEFTSIYFMLMNYWTLVESNNIAR
                     ERGITFHNFEKSDYANGSYFDKYVTGEFVPTSDRVKELFKNVFIPGVADWAELRDKVQ
                     EDGLYHQNRLAVAPNGSISYINDVSASIHPITQRIEERQEKKIGKIYYPAAGLSTETI
                     PYYTSAYDMDMRKVIDVYAAATEHVDQGLSLTLFMRSDIPKGLYEWKRENKQTTRDLS
                     ILRNYAFNKGIKSIYYVRTFTDDGGEVGANQCESCVI"
     gene            complement(4175..4393)
                     /gene="nrdH"
                     /locus_tag="VYO11_001927"
     CDS             complement(4175..4393)
                     /gene="nrdH"
                     /locus_tag="VYO11_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000259243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HEV1596428.1"
                     /translation="MVTVYSKNNCVQCKMTKRFLDSNNVSYREINLDEQPEYVDQVKE
                     LGFSAAPVIQTPTEVFSGFQPGKLKQLA"
     gene            4744..5007
                     /locus_tag="VYO11_001928"
     CDS             4744..5007
                     /locus_tag="VYO11_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019775469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HEV1596429.1"
                     /translation="MASKDFHVVAETGIHARPATLLVQTASKFASDITLEYKGKSVNL
                     KSIMGVMSLGVGQGADVTISAEGADADDAIAAISETMEKEGLA"
     gene            5013..6746
                     /gene="ptsP"
                     /locus_tag="VYO11_001929"
     CDS             5013..6746
                     /gene="ptsP"
                     /locus_tag="VYO11_001929"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HEV1596430.1"
                     /translation="MTEMLKGIAASDGVAVAKAYLLVQPDLSFETITVEDTNAEEARL
                     DAALQASQDELSVIREKAVGTLGEEAAQVFDAHLMVLADPEMISQIKETIRAKKVNAE
                     AGLKEVTDMFITIFEGMEDNPYMQERAADIRDVTKRVLANLLGKKLPNPASINEEVIV
                     IAHDLTPSDTAQLDKNFVKAFVTNIGGRTSHSAIMARTLEIAAVLGTNNITEIVKDGD
                     ILAVNGITGEVIINPTDEQAAEFKAAGEAYAKQKAEWALLKDAQTVTADGKHFELAAN
                     IGTPKDVEGVNNNGAEAVGLYRTEFLYMDSQDFPTEDEQYEAYKAVLEGMNGKPVVVR
                     TMDIGGDKELPYFDMPHEMNPFLGFRALRISISETGDAMFRTQIRALLRASVHGQLRI
                     MFPMVALLKEFRAAKAVFDEEKANLLAEGVAVADNIQVGIMIEIPAAAMLADQFAKEV
                     DFFSIGTNDLIQYTMAADRMNEQVSYLYQPYNPSILRLINNVIKAAHAEGKWAGMCGE
                     MAGDQQAVPLLVGMGLDEFSMSATSVLRTRSLMKKLDTAKMEEYANRALTECSTMEEV
                     LELQKEYVNFD"
     gene            7001..9451
                     /gene="phtA"
                     /locus_tag="VYO11_001930"
     CDS             7001..9451
                     /gene="phtA"
                     /locus_tag="VYO11_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtA"
                     /protein_id="HEV1596431.1"
                     /translation="MKINKKYLVGSAAALILSVCSYELGLYQARTVKENNRVSYIDGK
                     QATQKTENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIFSEE
                     LLMKDPNYKLKDEDIVNEVKGGYVIKVDGKYYVYLKDAAHADNVRTKEEINRQKQEHS
                     QHREGGTPRNDGAVALARSQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKN
                     ELSASELAAAEAFLSGRGNLSNSRTYRRQNSDNTSRTNWVPSVSNPGTTNTNTSNNSN
                     TNSQASQSNDIDSLLKQLYKLPLSQRHVESDGLVFDPAQITSRTARGVAVPHGDHYHF
                     IPYSQMSELEERIARIIPLRYRSNHWVPDSRPEQPSPQPTPEPSPGPQPAPNLKIDSN
                     SSLVSQLVRKVGEGYVFEEKGISRYVFAKDLPSETVKNLESKLSKQESVSHTLTAKKE
                     NVAPRDQEFYDKAYNLLTEAHKALFENKGRNSDFQALDKLLERLNDESTNKEKLVDDL
                     LAFLAPITHPERLGKPNSQIEYTEDEVRIAQLADKYTTSDGYIFDEHDIISDEGDAYV
                     TPHMGHSHWIGKDSLSDKEKVAAQAYTKEKGILPPSPDADVKANPTGDSAAAIYNRVK
                     GEKRIPLVRLPYMVEHTVEVKNGNLIIPHKDHYHNIKFAWFDDHTYKAPNGYTLEDLF
                     ATIKYYVEHPDERPHSNDGWGNASEHVLGKKDHSEDPNKNFKADEEPVEETPAEPEVP
                     QVETEKVEAQLKEAEVLLAKVTDSSLKANATETLAGLRNNLTLQIMDNNSIMAEAEKL
                     LALLKGSNPSSVSKEKIN"
BASE COUNT         3034 a         1787 c         1984 g         2793 t
ORIGIN      
        1 agaattattt aaagcgatgc gttgagcctc tccctcttcc tcgctaaaag tagctagagc
       61 tccgttttga ataccattac agctaacgaa agctttagaa aattggagat tagagagatt
      121 ttgtagggtc aatgtaccaa caaaagcacc tgtaatatcg cgataatttc cacctattaa
      181 aatcaaatct gttaattttc gttcgcttaa aatcagaaaa acaggtagac tgttggttac
      241 gacgcggata ttgtcaatag gcaactcacg cgcaaaaaac tctaatgttg ttcctggtcc
      301 aatgaaaata gtttctcttt cttctactag actgcctgca aaatgggcta tttcttgttt
      361 ttctgccgtt tggagggctt gtttttcaat atttgatcgc tcattagtca aaagggagtt
      421 ggttcgaagt ttttcagctc caccatgcac acgaatcagc aaatctttat cagctaattc
      481 ctgtaaatag cgccttgcag tcatatctga aacggctatt tcgtccataa tctgtttaac
      541 tgttatggtt cctttactat ttactatctc taaaattttg gttaattttt cttgtttgag
      601 catattatca cctcgtttcc tactactatc ttaccataaa caaactcatc attcaaatac
      661 aaaaacaaca aaatgaaaca aaaacaaaaa tatcgaagtt tgttttcaaa actttcgata
      721 tttttgttgg gttataactt tgatgtttct agtttacttt ttgatgattg agagtgatgg
      781 agaattagtc taaaccgtag ttatagtcat cgtcttgcat ggcttcaact tcgccaagaa
      841 ggtaaccatt tccgacttga gagaagaagt catggttgga agttcctgtt gaaataccgt
      901 tcataacgat tgggttgaca tcttcagctg aatctgggaa aagtggatct tgtcccatgt
      961 tcatgagagc tttattggca ttgtagcgaa ggaaggtttt aacctcttca gtccaaccaa
     1021 caccgtcata aagactctct gtgtagcctt cttcattttc ataaagagta tagagtaggt
     1081 cgtacatcca ttctttgagt ttttcttgct cttcttcagg caattcattg aaaccaagtt
     1141 ggaatttgta accaatgtag gttccgtgaa cagactcgtc acgaataatc aatttaatga
     1201 tttctgcaac gttggctagt ttgttgttac cgagatagta gaggggagtg aagaaaccag
     1261 agtagaagag gaaggtttcg aggaagacgc tggcaacttt cttttcaagt gggctgccgt
     1321 ttaggtagat ttcgttgaca atctcagcct tcttttgtag gtaaggattg gtattggtcc
     1381 attcgaaaat ttcttcaatc tcagccttag tattcaaggt agaaaagatt gatgagtaag
     1441 atttagcgtg gacagattcc ataaattgga tgttattgaa aacagcttcc tcatgtggtg
     1501 tacggatgtc tgcgcgaagg gcttgaaccc cagtttcaga ttgcatagtg tcaagaaggg
     1561 ttaaaccacc aaaaactttt ccgaccaagt ctttctcttt gttagatagc tttctccagt
     1621 catccaagtc gtttgataag ggaatacgtg tatcgagcca aaattgctcc gtcagttttt
     1681 cccaagttga tttgtcgatg acatcttcga tggcattcca gttaatggct ttgtagtaag
     1741 tttccattta aaatctcttt ctgtgtttag tattgcgaac tcacaattat ttctacttta
     1801 ccataattct ataggagtat cgcacaaaaa gtcggaagcc cgacttttaa aatgttacat
     1861 aaattatgtt atgacatagt agatttgatt ttatctgtgc tgcttaggga aaaataatgt
     1921 ttctatgcta gaaactaaat cacacagctt tcacattggt tggcgccgac ttctccaccg
     1981 tcatctgtaa aggtacggac gtagtagata gacttgattc ccttgttaaa ggcatagtta
     2041 cgaaggatgg acaagtcacg tgtcgtttgt ttattttccc tcttccattc gtaaaggcct
     2101 tttggaatgt cactgcgcat gaagagggtg agtgaaagtc cttgatccac gtgttcagtc
     2161 gcagcagcgt aaacatcgat gactttacgc atatccatat cgtaggcaga agtgtagtaa
     2221 ggaatggttt ctgtagacaa gccagcagca gggtagtaga ttttaccaat tttcttctct
     2281 tggcgttctt cgatacgttg cgtaatcggg tggatagaag cagaaacgtc gttgatatag
     2341 ctgatagaac catttggcgc tacagcaagg cgattttggt ggtaaagacc atcttcttga
     2401 accttgtcgc gaagttcagc ccaatcagca acaccaggga taaagacatt tttgaagagt
     2461 tctttaacac ggtctgatgt tggaacaaat tcaccagtta catacttgtc aaagtaactt
     2521 ccgttagcat agtctgattt ttcaaagttg tggaaggtaa taccacgttc acgtgcaata
     2581 ttgtttgact ctaccaaggt ccagtagttc ataagcataa agtagatgct tgtaaattca
     2641 acagactcag gtgaaccata ttcaatgagt tgttgggcaa ggtagctgtg cagtcccatg
     2701 gcaccgagac caaaggtgtg ggcttggcta tttccatggt caatcgttgg tacagctacg
     2761 atatgtgaac tatctgtaac gaaagtaagg gcacgaacca tagcacggat agaacgacca
     2821 aaatcaggtg aagtcatcat gttaaccacg ttggttgaac ccaggttaca tgaaacatct
     2881 gttcccattt gaaggaattc ttgagcatcg ttgatcaagc ttggttcttg aacttgaaga
     2941 atctcagaac acaagttact catgataatc tttccatcaa caggatttgc acggttagcc
     3001 gtatcgatgt tgactacata aggatagcca gactcttgtt gcaatttaga gatttcagtt
     3061 tccaaatccc gcgccttgat ttttgtcttg cgaatatttg gatttgcgac caattcatcg
     3121 tatttttcag taatgtcgat gtaattgaat ggcacaccgt attctttttc tacagagtaa
     3181 gggctgaaga ggtacatttc ttcattttta cgagccaatt cgtagaattt atcaggtact
     3241 acaacaccaa gtgatagagt cttgacacgt actttttcat cagcgttttc tttcttagtt
     3301 gaaaggaaag cgatgatatc tgggtgaaag acgttgaggt agacaacgcc ggcaccttga
     3361 cgttgcccca attggttgga gtaagagaag ctgtcttcaa aaagcttcat aacaggaacg
     3421 acacctgaag cagctccttc atagcctttg ataggtgcac cagcttcacg aaggttgctg
     3481 agggtaattc ccacaccacc accaatacgt gaaagttgaa gagctgagtt gatagaacgc
     3541 ccgatagagt tcatatcatc cgtcacttgg attaggaaac aagataccaa ctccccacga
     3601 cgagcacgtc cagcattcaa gaaggaagga gtagcaggtt ggtagcgttg gtggatgatt
     3661 tcattggcaa tatcgattgc aacagcttca ttcccatcag cgaaataaag ggcgttgaag
     3721 aagacacggt cttccatatt ttcaagatag tattcaccgt cattagtctt taaggcatat
     3781 tgattgtaaa atttataagc tgccatgaat gacttgaatt ggaagttttg gtctttgata
     3841 aattgagcca attcttccaa gaactctgga cggtatttct tgataaaggc tgtttcgatg
     3901 tagttgtgtt caatgaggta attgattttg tctttgattg aatcaaaaac catagtgttt
     3961 ggaactacat tttctttaaa gaaagcatcc aaggcttcct tatctttatg aagcatgatt
     4021 tgtccattaa caggacggtt aatttcgtta ttaagacgga agtaagtcac gtcttcaaga
     4081 tgttttaatc ccataaaatt tcccttatct aattacaaaa gaaaggcttc taagttagcc
     4141 ctaaaagcag tttcttctgg atgatgtact aagattatgc taattgtttc agttttcctg
     4201 gttggaaacc tgaaaagact tcagttggtg tttggataac aggagctgcg ctaaaaccga
     4261 gctctttaac ttgatcgacg tactcaggtt gctcatcaag attgatttca cgataagaga
     4321 cattattact gtccaagaaa cgcttggtca ttttacattg gacacaattg tttttagaat
     4381 aaacggttac cattgtgtaa ctcctcttca aaatttaata ctatcttagt atatcagaaa
     4441 ataaaatttt gtcaatgatt taaactaaat atagtggtgt tcttttgttg tttttatata
     4501 taaacacaat atatagtgtt tgcattgtga aatagcaatg attatcctat aaattgtttt
     4561 tgaagaaact atatcctgtg ttttgttctc taggatagaa gattttcagc aagttatctg
     4621 aaaggaaatt gaaggaaaat ccagaaaatg cttgaaaaaa atcctagaag atggtataat
     4681 actaaattgt aagggttatc acatataact caaaaaaaga aagaacaaaa ggagagtcaa
     4741 actatggctt ctaaagattt ccacgtagtg gcagaaacag gtattcacgc acgtccagca
     4801 acattgttgg tacaaactgc tagcaaattt gcttcagata tcactcttga gtacaaaggt
     4861 aaatcagtta accttaaatc aattatgggt gttatgagtc ttggtgttgg ccaaggtgct
     4921 gacgtaacta tctcagctga aggtgcagat gcagatgacg ctatcgctgc aatctcagaa
     4981 acaatggaaa aagaaggatt ggcataaggg aaatgacaga aatgcttaaa ggaatcgcag
     5041 catctgacgg tgttgcagtt gcaaaagcat atctactcgt tcagccggat ttgtcatttg
     5101 agactattac agtcgaagat acaaacgcag aagaagctcg ccttgatgcc gctctacagg
     5161 catcacaaga cgagctttct gttattcgcg agaaagcagt aggtacgctc ggtgaagaag
     5221 cagctcaagt ttttgatgct cacttaatgg ttcttgctga cccagaaatg atcagccaaa
     5281 tcaaggaaac tatccgtgcg aagaaagtga atgcagaagc aggtctgaaa gaagttacag
     5341 atatgtttat cactatcttt gaaggcatgg aagacaaccc atacatgcaa gaacgcgcag
     5401 cggatatccg cgacgtgaca aaacgtgtat tggcaaacct tcttggtaaa aaattgccaa
     5461 acccagcttc tatcaatgaa gaagtgattg tgattgcgca tgacttgact ccttcagata
     5521 cagctcaatt ggacaaaaac tttgtaaaag cttttgtaac caacattggt ggacgtacaa
     5581 gccactcagc tatcatggca cgtacacttg aaattgctgc tgtattaggt acaaacaaca
     5641 tcactgaaat cgttaaagac ggtgacatcc ttgctgttaa cgggatcact ggagaagtga
     5701 ttatcaaccc aacagatgaa caagcggcag aatttaaagc agctggtgaa gcctatgcga
     5761 aacaaaaagc tgaatgggca cttttgaaag atgctcaaac agtgactgct gacggtaaac
     5821 acttcgagtt ggctgccaat attggtactc caaaagacgt tgaaggtgtt aacaacaacg
     5881 gtgcagaagc tgttggactt taccgtacag agttcttgta catggattct caagacttcc
     5941 caactgaaga tgagcagtat gaagcataca aggctgttct tgaaggaatg aacggtaaac
     6001 ctgttgtcgt tcgtacaatg gatatcggtg gagataagga acttccttac ttcgatatgc
     6061 ctcacgaaat gaacccattc cttggattcc gtgctcttcg gatctctatc tctgagactg
     6121 gagatgctat gttccgcaca caaatccgtg ctcttcttcg tgcgtctgtt cacggtcaat
     6181 tgcgtatcat gttcccaatg gttgcgctct tgaaagaatt ccgtgcagcg aaagcagtct
     6241 ttgatgaaga aaaagcaaac cttcttgctg aaggtgttgc agttgcggat aacattcaag
     6301 ttggtatcat gatcgagatt cctgcagcgg ctatgcttgc agaccaattt gctaaagaag
     6361 ttgacttctt ctcaattggt acaaatgact tgatccaata tacaatggca gcagaccgta
     6421 tgaacgaaca agtttcatac ctttaccaac catacaaccc atcaatccta cgcttgatta
     6481 acaatgtgat caaagcagct cacgctgaag gtaaatgggc tggtatgtgt ggtgagatgg
     6541 ctggtgacca acaagctgtt ccacttcttg tcggaatggg cttggatgag ttctctatgt
     6601 cagcaacatc tgtacttcgt acacgcagct tgatgaagaa actcgacaca gctaagatgg
     6661 aagagtacgc aaaccgtgcc cttacagaat gctcaacaat ggaagaagtt cttgaacttc
     6721 aaaaagaata cgttaatttt gattaatcga aaagtccctg caactcagtt acagggactt
     6781 tttttgatat tttaaaaaga attttcaaga aaatctttct tataaaaagt ccaaccttga
     6841 aaaagtagtg gtcagaacaa aaaatactta aatggttcat aaaattcttg acaagttgga
     6901 gatttaggag taaactatta accagttaag taatagagag gagtttctgc aatttagaaa
     6961 tgaattgcaa ctagaaatat caaatagaaa gagagtttcg atgaaaatta ataagaaata
     7021 ccttgttggt tctgcggcag ctttgatttt aagtgtttgt tcttacgagt tgggactgta
     7081 tcaagctaga acggttaagg aaaataatcg tgtttcctat atagatggaa aacaagcgac
     7141 gcaaaaaacg gagaatttga ctcctgatga ggttagcaag cgtgaaggaa tcaatgctga
     7201 gcaaatcgtc atcaagataa cagaccaagg ctatgtcact tcacatggcg accactatca
     7261 ttattacaat ggtaaggttc cttatgatgc gattttcagt gaagaattac tcatgaaaga
     7321 tccaaactat aagctaaaag atgaggatat tgttaatgag gtcaagggtg gatatgttat
     7381 caaggtagat ggaaaatact atgtttacct taaggatgct gcccacgcgg ataacgtccg
     7441 tacaaaagag gaaatcaatc gacaaaaaca agaacatagt caacatcgtg aaggtgggac
     7501 tccaagaaac gatggtgctg ttgccttggc acgttcgcaa ggacgctata ctacagatga
     7561 tggttatatc tttaatgctt ctgatatcat agaggatact ggtgatgctt atatcgttcc
     7621 tcatggagat cattaccatt acattcctaa gaatgagtta tcagctagcg agttggctgc
     7681 tgcagaagcc ttcctatctg gtcggggaaa tctgtcaaat tcaagaacct atcgccgaca
     7741 aaatagcgat aacacttcaa gaacaaactg ggtaccttct gtaagcaatc caggaactac
     7801 aaatactaac acaagcaaca acagcaacac taacagtcaa gcaagtcaaa gtaatgacat
     7861 tgatagtctc ttgaaacagc tctacaaact gcctttgagt caacgacatg tagaatctga
     7921 tggccttgtt ttcgacccag cgcaaatcac aagtcgaaca gctagaggtg ttgcagtgcc
     7981 acacggagat cattaccact tcatccctta ctctcaaatg tctgaattgg aagaacgaat
     8041 cgctcgtatt attccccttc gttatcgttc aaaccattgg gtaccagatt caaggccaga
     8101 acaaccaagt ccacaaccga ctccggaacc tagtccaggc ccgcaacctg caccaaatct
     8161 taaaatagac tcaaattctt ctttggttag tcagctggta cgaaaagttg gggaaggata
     8221 tgtattcgaa gaaaagggca tctctcgtta tgtctttgcg aaagatttac catctgaaac
     8281 tgttaaaaat cttgaaagta agttatcaaa acaagagagt gtttcacaca ctttaactgc
     8341 taaaaaagaa aatgttgctc ctcgtgacca agaattttat gataaagcat ataatctgtt
     8401 aactgaggct cataaagcct tgtttgaaaa taagggtcgt aattctgatt tccaagcctt
     8461 agacaaatta ttagaacgct tgaatgatga atcgactaat aaagaaaaat tggtagatga
     8521 tttattggca ttcctagcac caattaccca tccagagcga cttggcaagc caaattctca
     8581 aattgagtat actgaagacg aagttcgtat tgctcaatta gctgataagt atacaacgtc
     8641 agatggttac atttttgatg aacatgatat aatcagtgat gaaggagatg catatgtaac
     8701 gcctcatatg ggccatagtc actggattgg aaaagatagc ctttctgata aggaaaaagt
     8761 tgcagctcaa gcctatacta aagaaaaagg tatcctacct ccatctccag acgcagatgt
     8821 taaagcaaat ccaactggag atagtgcagc agctatttac aatcgtgtga aaggggaaaa
     8881 acgaattcca ctcgttcgac ttccatatat ggttgagcat acagttgagg ttaaaaacgg
     8941 taatttgatt attcctcata aggatcatta ccataatatt aaatttgctt ggtttgatga
     9001 tcacacatac aaagctccaa atggctatac cttggaagat ttgtttgcga cgattaagta
     9061 ctacgtagaa caccctgacg aacgtccaca ttctaatgat ggatggggca atgccagtga
     9121 gcatgtgtta ggcaagaaag accacagtga agatccaaat aagaacttca aagcggatga
     9181 agagccagta gaggaaacac ctgctgagcc agaagtccct caagtagaga ctgaaaaagt
     9241 agaagcccaa ctcaaagaag cagaagtttt gcttgcgaaa gtaacggatt ctagtctgaa
     9301 agccaatgca acagaaactc tagctggttt acgaaataat ttgactcttc aaattatgga
     9361 taacaatagt atcatggcag aagcagaaaa attacttgcg ttgttaaaag gaagtaatcc
     9421 ttcatctgta agtaaggaaa aaataaacta atgaaaaatg aaagtctcga taaagaggct
     9481 ttcattttta ttatgtatat atgtaaaatt cttgacaagc aatattaaaa agagtaaact
     9541 attaactagt taattaaccg gtttattact ttatagtgaa tcaaatatac ttaagaaa
//
LOCUS       DAVLXH010000071         9189 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00028199
            SAMN33607166-rid17955573.denovo.072, whole genome shotgun sequence.
ACCESSION   DAVLXH010000071 DAVLXH010000000
VERSION     DAVLXH010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607166
            Sequence Read Archive: SRR23725544
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9189)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9189)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721421.1
            Genome Coverage       :: 115x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:42:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,210
            CDSs (total)                      :: 2,161
            Genes (coding)                    :: 2,023
            CDSs (with protein)               :: 2,023
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 73 of 138
            Pseudo Genes (incomplete)         :: 60 of 138
            Pseudo Genes (internal stop)      :: 40 of 138
            Pseudo Genes (multiple problems)  :: 31 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9189
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607166-rid17955573.denovo.072"
                     /strain="AUSMDU00028199"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1349"
     gene            31..1512
                     /locus_tag="VYO11_001931"
     CDS             31..1512
                     /locus_tag="VYO11_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001205273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV1596432.1"
                     /translation="MRDLLSKKSHRQLELLELLFEHKRWFHRSELAELLNCTERAVKD
                     DLSHVKSAFPDLIFHSSTNGIRIINTDDSDIEMVYHHFFKHSTHFSILEFIFFNEGCQ
                     AESICKEFYISSSSLYRIISQINKVIKRQFQFEVSLTPVQIIGNERDIRYFFAQYFSE
                     KYYFLEWPFENFSSEPLSQLLELVYKETSFPMNLSTHRMLKLLLVTNLYRIKFGHFME
                     VDKDSFNDQSLDFLMQAEGIEGVAQSFESEYNISLDEEVVCQLFVSYFQKMFFIDESL
                     FMKCVKKDSYVEKSYHLLSDFIDQISVKYQIEMENKDNLIWHLHNTAHLYRQELFTEF
                     ILFDQKGNTIRNFQNIFPKFVSDIKKELSHYLETLEVCSSSMMVNHLSYTFITHTKHL
                     VINLLQNQPKLKVLVMSNFDQYHAKFVAETLSYYCSNNFELEVWTELELSKESLEDSS
                     YDIIISNFIIPPIENKRLIYSNNINTVSLIYLLNAMMFIRLDE"
     gene            1874..2875
                     /locus_tag="VYO11_001932"
     CDS             1874..2875
                     /locus_tag="VYO11_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV1596433.1"
                     /translation="MVEQRKSITMKDVALEAGVSVGTVSRVINKEKGIKEVTLKKVEQ
                     AIKTLNYIPDYYARGMKKNRTETIAIIVPSIWHPFFSEFAMHVENEVYKRNNKLLLCS
                     INGTNREQDYLEMLRHNKVDGVVAITYSPIEHYLTSGIPFVSIDRTYSDIAIPCVSSD
                     NDAGGREAAKQLISKGCQHLAFVGGHNTTINETKRRRISFEKYVQEHKIPLSIFDLDE
                     TVTDYYGKLESFLEENSSIDGIFTINDFTALDVIEILKKNGKRIPHDVQIIGYDGIKM
                     AGDRDYLLSTIEQPLEEMAKEAVRILFDIIDGKTVNLQTILPVKFVEGKTTKNENKS"
     gene            3024..3941
                     /locus_tag="VYO11_001933"
     CDS             3024..3941
                     /locus_tag="VYO11_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001084977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV1596434.1"
                     /translation="MNSKAKQVSLWERIKKQKLLLLMTVPGLVLTFIFKYIPMYGVLI
                     AFKDYNPLKGILGSDWIGFSEFTKFISSPNFGILLANTLKLSIYGLLLGFLPPIILAI
                     MLNQLLSEKVKKRIQLILYAPNFISVVVIVGMIFLFFSVGGPINNFLSMFGMKADFLT
                     NPDFFRPLYIFSGIWQGMGWASTLYTATLVNVDPALVEAARLDGANIFQRIWHIDIPA
                     LKPIMVIQFVLAAGGIMNVGYEKAFLMQTSLNLPTSEIISTYVYKVGLVSGDYSYSTA
                     VGLFNAVINVVLLVAVNQIVKRMNNGEGI"
     gene            3952..4842
                     /locus_tag="VYO11_001934"
     CDS             3952..4842
                     /locus_tag="VYO11_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEV1596435.1"
                     /translation="MKNSIMDTKFDRRILLLNKIIIVFIVLMTLLPLLYIVVASFMDP
                     KVLVSRGISFNPADWTVEGYQRVFSDQSILRGFINSLLYSFGFAALTVLLSVFTAYPL
                     SKKDLVGRRWINYFLIVTMFFGGGLVPTYLLVKELGMLNTPWAIIVPGAVNVWNIILA
                     RAYFQGLPEELVEAAVIDGANDLQIFFKIMLPLAKPIMFVLFLYAFVGQWNSYFDAMI
                     YIKDPNLEPLQLVLRKILIQSQPGQDMIGAQAAMNEMKRLAELIKYATIVISSLPLIV
                     MYPFFQKYFDKGIMAGSLKG"
     gene            4871..6487
                     /locus_tag="VYO11_001935"
     CDS             4871..6487
                     /locus_tag="VYO11_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEV1596436.1"
                     /translation="MKFKTFSKSAVLLTASLAVLAACGSKNTASSPDYKLEGVTFPLQ
                     EKKTLKFMTASSPLSPKDPNEKLILQRLEKETGVHIDWTNYQSDFAEKRNLDISSGDL
                     PDAIHNDGASDVDLMNWAKKGVIIPVEDLIDKYMPNLKKILDEKPEYKALMTAPDGHI
                     YSFPWIEELGDGKESIHSVNDMAWINKDWLKKLGLEMPKTTDDLIKVLEAFKNGDPNG
                     NGEADEIPFSFISGNGNEDFKFLFAAFGIGDNDDHLVVGNDGKVDFTADNDNYKEGVK
                     FIRQLQEKGLIDKEAFEHDWNSYIAKGHDQKFGVYFTWDKNNVTGSNESYDVLPVLAG
                     PSGQKHVARTNGMGFARDKMVITSVNKNLELTAKWIDAQYAPLQSVQNNWGTYGDDKQ
                     QNIFELDQASNSLKHLPLNGTAPAELRQKTEVGGPLAILDSYYGKVTTMPDDAKWRLD
                     LIKEYYVPYMSNDNNYPRVFMTQEDLDKIAYIEADMNDYIYRKRAEWIVNGNIDTEWD
                     DYKKELEKYGLSDYLAIKQKYYDQYQANKN"
     gene            6497..7816
                     /locus_tag="VYO11_001936"
     CDS             6497..7816
                     /locus_tag="VYO11_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HEV1596437.1"
                     /translation="MGDKKYTVEKANRFIAENKHLVNTQYKPEEHFSAEIGWINDPNG
                     FVYFRGEYHLFYQFYPYDSVWGPMHWGHAKSKDLVTWEHLPVALAPDQDYDRNGCFSG
                     SAIVKDDRLWLMYTGHIEEKTGVRQVQNMAFSDDGIHFEKIEQNPVATGADLPDELIA
                     ADFRDPKLFEKDGRYYSVVAAKHKDNVGCIVLLGSDNLVEWQFESIFLKGVEHQGFMW
                     ECPDYFELDGKDCLIMSPMRYQREGDSYHNINSSLLFTGKVDWREKRFIPESVQEIDH
                     GQDFYAPQTLLDDQNRRILIAWMQTWGRTLPTHDQEHKWACAMTLPRILRLEDGKLRQ
                     FPVKKGQYQIQIDKDCHYHLGNDIDYLEFGYDSNAQQVYIDRSHLIQKILGEEEQDTS
                     RRYVDIEAKELEVVLDKNSIEIFVNQGEASLTATYYLTVPAELSRID"
     gene            8212..8643
                     /locus_tag="VYO11_001937"
     CDS             8212..8643
                     /locus_tag="VYO11_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000794283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1596438.1"
                     /translation="MKNNERLGIKLSRDSVLGLREVRRLYLGSSDIPVPDSYVIEVAY
                     KQISNEIDIIDWVELNKSKIKISEISESVDIDATSLRTTLTLDTLVYEGMRDIQLKLR
                     ELTKGRVFFSFVVKLVLFASILKKKGLLEKFQESVNQVLTF"
     gene            8875..>9189
                     /locus_tag="VYO11_001938"
     CDS             8875..>9189
                     /locus_tag="VYO11_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000810873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1596439.1"
                     /translation="MKQKQPIVARTKQHTFEELIQDQKLERLAKFSPDLVGRYGFTAS
                     CASSFANLIKEAYGGKNLNVVYASRMLALWNIACSCYHKADGYSLADALFSDKKICLD
                     YFY"
BASE COUNT         3083 a         1389 c         1774 g         2943 t
ORIGIN      
        1 ccgataattt ataaagagag aaagatattc atgagagatt tattatctaa aaaaagtcat
       61 aggcaattag aattattaga attattattt gaacataaac gttggtttca tcgttctgaa
      121 ctagcagagt tattaaattg tacagaacgt gcagtcaaag atgatctatc ccatgttaaa
      181 tctgcttttc ctgacttgat ttttcattct tctactaatg gtatacgcat tattaatacc
      241 gatgatagtg atattgaaat ggtttaccat catttcttta aacattcaac tcatttttcg
      301 attttagaat tcatcttctt taatgaaggt tgtcaagctg agagtatttg taaagaattt
      361 tatatcagtt catcttcgct ctatcgtatt attagccaaa tcaataaagt gattaaaagg
      421 caatttcaat ttgaagtcag tctgacccct gttcaaatca ttggaaatga gagagacatt
      481 cgttactttt ttgcacaata tttttcagaa aaatattatt tcctagaatg gccatttgaa
      541 aatttttcat cagagccact atctcaattg ttagaattgg tttataagga aacaagcttt
      601 ccaatgaatt tgtcaacgca tagaatgcta aagttgctcc tagttacgaa cctatataga
      661 ataaagtttg gtcattttat ggaagtagat aaagattctt ttaacgacca aagtttggat
      721 tttttaatgc aggcagaagg aatagaaggt gttgctcaga gttttgaatc agaatacaat
      781 atctctttag atgaagaagt tgtttgccaa ttatttgtgt cttactttca aaaaatgttt
      841 ttcatagatg aaagtctctt tatgaaatgc gtaaaaaagg atagttatgt tgaaaaatct
      901 taccatctat tgagtgattt tattgatcag atttcagtca agtatcagat tgaaatggag
      961 aataaggata atctgatttg gcatctgcat aataccgcac atctgtatcg tcaagagttg
     1021 tttactgagt ttattttatt tgatcaaaaa gggaatacaa tcaggaactt tcaaaatatt
     1081 tttccaaaat ttgtttcaga tataaaaaaa gagctttctc actatttaga gactcttgag
     1141 gtttgttcta gttcaatgat ggtaaatcat ctatcttata ccttcatcac tcataccaaa
     1201 catttggtga ttaatttgct acaaaatcag cctaaactaa aggttttagt tatgagtaat
     1261 tttgatcagt atcatgcaaa attcgttgca gagacacttt cttattactg tagcaataat
     1321 tttgaactgg aagtttggac tgaattagaa ttatcaaagg aatctttaga agattcatct
     1381 tatgatatca ttatttctaa ttttattatt cctcctattg aaaataagag actcatctat
     1441 tcaaataata taaacacggt ctcactcata tatttgttaa atgccatgat gtttattcga
     1501 ttagatgagt aaccaaaaat aacaaaaaaa cgctatttcg cgtttgaact gtacctcaaa
     1561 agttagacag aaaaagtcta atttttgggg tgtttttgtt aagaaaatac cttcaatcat
     1621 ttaagcaaaa tgtacatcta gatttatagc catctaaaac tcttgctttt tttgtagaag
     1681 atacgaaaaa agccatgaaa ccaaggcttt tcctgtttta tgtagatgtt tacacatgaa
     1741 aattgaagta ttttcaaaag ctaattggag tgattttatt catgatggga taaatgatct
     1801 ggccaaaaat gattgagaaa tagttgctta aaaagcattt gcatgatact atatattgaa
     1861 aggaggtgat aatatggtag aacaaagaaa atcaattacc atgaaagatg ttgctttaga
     1921 agcaggagtt agtgttggaa ctgtttcacg tgtaattaat aaagaaaaag gcattaaaga
     1981 agtaactttg aaaaaagtgg aacaagcgat taaaactttg aattacattc cagattacta
     2041 cgctagagga atgaaaaaaa atcgaacaga aacgattgca atcattgtac caagtatctg
     2101 gcatcccttc ttttcagaat ttgctatgca tgtggaaaat gaagtctata agagaaataa
     2161 caaattactc ttatgttcta tcaatggtac aaatagagag caagactatc tggagatgtt
     2221 gcgtcataat aaagttgatg gagtggttgc cattacctat agtccaattg aacattactt
     2281 gacgtcagga attccctttg ttagtattga ccgcacatac tcagatattg ccattccttg
     2341 tgtttcatca gataatgatg caggtggaag agaagcagct aaacaattaa ttagtaaagg
     2401 atgtcagcat ttagcctttg tgggcggaca taatacaacc attaatgaaa ccaaacgtcg
     2461 tagaatttca tttgaaaagt atgtccaaga gcataaaata cctcttagta tttttgattt
     2521 ggatgagaca gttactgact attatggaaa gctagagagt ttcttggaag aaaattcttc
     2581 tatagatgga atttttacaa tcaacgattt tacagctttg gatgtgattg aaatactaaa
     2641 aaaaaatggc aaacgtattc ctcatgatgt tcaaattatt ggatacgatg gaattaaaat
     2701 ggctggagat agagattatc tactttcaac tattgaacaa ccattggaag aaatggcaaa
     2761 agaagcggtt cgtattttgt ttgatataat tgatggaaag actgttaatt tgcagacaat
     2821 cctaccagta aaatttgttg aaggaaaaac aacaaaaaat gaaaataagt cttgacagaa
     2881 agcgctatca atgatagaat gaattcagat aaaaagattt atttttaaaa caaaaatgaa
     2941 acgtttcaaa aaaagaaata aagagacagc gtcaagcgct atcttttcta gaaaaaatga
     3001 aacgtttcaa aaaggaggtt gctatgaata gcaaagcgaa gcaagtttct ctttgggaaa
     3061 gaatcaagaa acaaaaactc ttgttattga tgactgtccc cggtttagtt ttaaccttta
     3121 tctttaaata catccctatg tatggggttt taatcgcatt taaagattac aatcctttaa
     3181 aaggaatttt agggagtgat tggattggtt tttctgagtt tacaaaattc atatcctctc
     3241 ccaactttgg tatcttgtta gccaacacat taaaattaag tatctatggt ttattgcttg
     3301 gctttttacc accaatcatt cttgctatta tgctcaatca actcttgagt gaaaaagtca
     3361 aaaaacgaat tcagctcatt ttatacgcac caaactttat ctcagtcgtt gttattgtcg
     3421 gtatgatttt cctcttcttt tcagtgggag gaccaatcaa caattttctt tctatgtttg
     3481 gaatgaaggc tgacttcttg acaaatccag acttctttag acctttatac atctttagtg
     3541 gtatctggca aggaatgggc tgggcttcaa cgctctacac ggcaacattg gtaaatgtag
     3601 atccagcctt agtagaagca gctcgactgg atggagccaa tatcttccaa cgaatctggc
     3661 acattgatat tccagctctt aagcctatta tggttatcca atttgtttta gctgcaggtg
     3721 gaattatgaa tgtcggatat gaaaaagcat tcttgatgca gacatcgtta aatttgccaa
     3781 cttctgaaat tatctcgaca tatgtctata aagttggtct tgtatcagga gactattctt
     3841 actcaacagc ggttggtttg tttaatgcag tgattaacgt agtattgctt gttgcagtta
     3901 accaaatcgt taaacgcatg aataatggtg aaggaattta aggaggaaag tatgaaaaat
     3961 tcgattatgg atacaaaatt tgatagacgt atcttactct taaataaaat cattattgtc
     4021 tttatcgttt tgatgacttt gcttccttta ctttatatcg tcgtagcatc ctttatggat
     4081 cctaaggttc tggttagtag agggattagc tttaatccag ccgattggac tgtagaaggt
     4141 taccagcgtg tattcagtga ccaatctatt ctaagaggtt ttatcaattc tctactatac
     4201 tcttttggat ttgcagcttt aacagtcttg ctatctgtgt ttacagctta tcctctttct
     4261 aagaaagact tggttggacg tcgttggatt aactacttct tgattgtaac tatgttcttt
     4321 ggtggtggtt tagtcccaac ttacttgctc gtaaaagaat tgggaatgct caatactcca
     4381 tgggctatca ttgttccagg tgctgtcaat gtttggaata ttattcttgc tagggcctat
     4441 ttccaaggat tgcctgaaga attagttgaa gctgctgtca ttgatggtgc aaatgattta
     4501 cagattttct ttaaaatcat gcttcctctt gcaaaaccaa ttatgtttgt tctcttcctc
     4561 tatgcttttg taggacagtg gaactcatac tttgatgcaa tgatttatat caaggatcca
     4621 aacttggaac cattgcaact tgtacttcgt aaaattctca ttcagagcca accaggtcaa
     4681 gacatgattg gagcacaagc ggctatgaat gaaatgaaac gtttagctga attgattaaa
     4741 tacgcaacta ttgtcatttc cagcttgcca ttgattgtta tgtatccatt cttccaaaaa
     4801 tactttgata aaggaattat ggctggttca cttaaaggat aaaaaaagaa aaaataaaag
     4861 gagttttctc atgaaattca aaacattctc aaaatcagca gttttgttga cagctagttt
     4921 agcagtactt gcagcctgtg gctcaaaaaa tacagcttca agtccagatt ataagttgga
     4981 aggtgtaaca ttcccgcttc aagaaaagaa aacattgaag tttatgacag ccagttcacc
     5041 gttatctcct aaagacccaa atgaaaagtt aattttgcaa cgtttggaga aggaaactgg
     5101 cgttcatatt gactggacca actaccaatc cgactttgca gaaaaacgta acttggatat
     5161 ttctagtggt gatttaccag atgctatcca caacgacgga gcttcagatg tggacttgat
     5221 gaactgggct aaaaaaggtg ttattattcc agttgaagat ttgattgata aatacatgcc
     5281 aaatcttaag aaaattttgg atgagaaacc agagtacaag gccttgatga cagcacctga
     5341 tgggcacatt tactcattcc catggattga agagcttgga gatggtaaag agtctattca
     5401 cagcgtcaac gatatggctt ggattaacaa agattggctt aagaaacttg gtcttgaaat
     5461 gccaaaaact actgatgatt tgattaaagt cctagaagct ttcaaaaacg gggatccaaa
     5521 tggaaatgga gaggctgatg aaattccatt ttcatttatt agtggtaacg gaaacgaaga
     5581 ttttaaattc ctatttgctg catttggtat aggggataac gatgatcatt tagtagtagg
     5641 aaatgatggc aaagttgatt tcacagcaga taacgataac tataaagaag gtgtcaaatt
     5701 tatccgtcaa ttgcaagaaa aaggcttgat tgataaagaa gctttcgaac atgattggaa
     5761 tagttacatt gctaaaggtc atgatcagaa atttggtgtt tactttacat gggataagaa
     5821 taatgttact ggaagtaacg aaagttatga tgttttacca gtacttgctg gaccaagtgg
     5881 tcaaaaacac gtagctcgta caaacggtat gggatttgca cgtgacaaga tggttattac
     5941 cagtgtaaac aaaaacctag aattgacagc taaatggatt gatgcacaat acgctccact
     6001 ccaatctgtg caaaataact ggggaactta cggagatgac aaacaacaaa acatctttga
     6061 attggatcaa gcgtcaaata gtctaaaaca cttaccacta aacggaactg caccagcaga
     6121 acttcgtcaa aagactgaag taggaggacc actagctatc ctagattcat actatggtaa
     6181 agtaacaacc atgcctgatg atgccaaatg gcgtttggat cttatcaaag aatattatgt
     6241 tccttacatg agcaatgaca ataactatcc aagagtcttt atgacacagg aagatttgga
     6301 caagattgcc tatatcgaag cagatatgaa tgactatatc taccgtaaac gtgctgaatg
     6361 gattgtaaat ggcaatattg atactgagtg ggatgattac aagaaagaac ttgaaaaata
     6421 cggactttct gattacctcg ctattaaaca aaaatactac gaccaatacc aagcaaacaa
     6481 aaactagagg ttgattatgg gagataagaa atacacagta gaaaaagcca atcgttttat
     6541 agcagaaaat aaacatctcg ttaatactca atataagcct gaagaacatt tttcagctga
     6601 gattggttgg atcaatgatc caaatggatt tgtttatttt cgtggagaat accatctctt
     6661 ttatcaattc tatccatatg atagtgtttg gggacctatg cactggggac atgctaaaag
     6721 taaggacttg gtgacttggg agcacttgcc agtggcactt gctcctgatc aagattatga
     6781 ccgaaatggt tgtttctcag gctctgccat tgtcaaggat gatcgcctct ggctcatgta
     6841 cactgggcat atcgaagaaa aaaccggtgt ccgccaagtg caaaatatgg cattttcaga
     6901 cgacgggatt cactttgaaa agattgaaca aaatccagtt gcaacaggag cagacttgcc
     6961 agatgagttg attgctgctg atttccgtga tccaaaactc tttgaaaaag atggacgcta
     7021 ttactccgta gtagctgcca aacacaagga taatgtgggc tgtatcgttc tactagggtc
     7081 cgataaccta gtagaatggc agttcgaatc catcttttta aaaggggtag aacaccaagg
     7141 gtttatgtgg gaatgcccag attacttcga gttagatggg aaagattgcc ttattatgtc
     7201 acccatgcgt tatcagcgtg agggagactc atatcataac atcaactcat cgcttttgtt
     7261 cacgggtaag gtagattgga gagaaaaacg ttttatccca gaatcagttc aagaaattga
     7321 tcatggccaa gacttctatg cgcctcaaac attgttggac gatcaaaatc gtcgtatcct
     7381 gattgcttgg atgcagacat gggggcgtac ccttccaacc catgaccaag aacacaaatg
     7441 ggcatgtgcc atgactttac ctagaattct aagattggaa gatggcaaac tgagacaatt
     7501 ccctgttaaa aaaggccaat atcaaatcca aatagataaa gattgtcatt accacttagg
     7561 aaatgatata gattatcttg aatttggtta tgacagtaat gcgcagcaag tttacattga
     7621 tcgtagccat cttattcaaa aaattctagg tgaagaagaa caggacacta gtcgacggta
     7681 tgtagatatt gaagctaaag aattggaagt tgttctagat aaaaattcca tcgagatttt
     7741 tgtcaatcaa ggtgaagcaa gcttgactgc aacttattac ttaacggtgc cagctgagct
     7801 atcacgaatt gattaaaaat taagttattt ctcctaaaga aaaagttctc tttctaaaat
     7861 agtggaaaga ggactttttg tgttttgggt atataagctt agtttatggt atttgtaaaa
     7921 ttggtgttgg attatgattt aagctagttt tctaaagaat ttgaaaaaaa ttttatttaa
     7981 gcaaaaaaac cttggttcca aggcttttcc tgttgtattt agatgccccc tacaggaatt
     8041 gtaggagata tgttgtttag atgttcttga ttttctggtg ttttgtaacg tttaaatgag
     8101 tttttttgag tttgttggtg gggcgttgcc cggcaattgc ccgacttatt gtttgaaaaa
     8161 gaatttaaaa tatggtatag ttaattatag attaacactt ggggggaata gatgaagaat
     8221 aatgaaagat taggtattaa attaagtaga gatagcgttt taggattgag ggaagttaga
     8281 aggctttatt taggcagttc agatatccca gttcctgata gctatgtgat tgaagttgct
     8341 tataaacaga tatcaaatga gattgatatt attgattggg tagagttgaa caagtcaaaa
     8401 attaagataa gtgaaattag tgaaagcgta gatatagatg ccactagctt gagaacaact
     8461 ttgactttag acacattagt atatgaaggt atgagagata tacagttaaa gttgagagag
     8521 cttacaaagg ggagagtatt cttttcattt gtagtgaagt tagttttatt tgcttctatt
     8581 ttaaagaaaa aaggtttact agaaaaattt caagaaagtg ttaatcaagt attgactttt
     8641 tagttgagtt caagtatact ttaattagag agatttctct ctaaattttt tcgcttcttt
     8701 tgtgttaatc aaagatgaat acaaaaacat atttttttgc tctaaaaagt gttaatcaat
     8761 gatgtatttg ttagagaggt agataaatgg aattgagagc accaccagtt ataacagtat
     8821 aaaacgtata ataaaaatat tttaacttga attatagaaa aggagaaaca aatcatgaaa
     8881 caaaaacaac cgattgttgc tagaacgaaa caacatacat ttgaagagct tattcaagac
     8941 caaaagttag aaagattagc taaattttcg cctgatctgg ttggaaggta tggttttact
     9001 gctagctgtg cgtcttcatt tgcgaacttg attaaagaag cgtatggggg taaaaatcta
     9061 aacgtagttt atgcgagtcg gatgttggct ctctggaata ttgcttgcag ttgttatcat
     9121 aaggctgatg ggtattcttt agcagatgcg ctttttagtg ataaaaaaat ttgtctagat
     9181 tatttttat
//
LOCUS       DAVLXH010000072         9096 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00028199
            SAMN33607166-rid17955573.denovo.073, whole genome shotgun sequence.
ACCESSION   DAVLXH010000072 DAVLXH010000000
VERSION     DAVLXH010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607166
            Sequence Read Archive: SRR23725544
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9096)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9096)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721421.1
            Genome Coverage       :: 115x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:42:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,210
            CDSs (total)                      :: 2,161
            Genes (coding)                    :: 2,023
            CDSs (with protein)               :: 2,023
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 73 of 138
            Pseudo Genes (incomplete)         :: 60 of 138
            Pseudo Genes (internal stop)      :: 40 of 138
            Pseudo Genes (multiple problems)  :: 31 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9096
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607166-rid17955573.denovo.073"
                     /strain="AUSMDU00028199"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1349"
     gene            49..912
                     /locus_tag="VYO11_001939"
     CDS             49..912
                     /locus_tag="VYO11_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1596440.1"
                     /translation="MNTLAEKFRLKRKELRLSQQTLAEGICEQSQISKIERGHFIPSA
                     DLLFKLSQRLEVPLDYFFNEQIEIKSNLSNFKQLSARLLDDRNYDNLEYIYRIEIERS
                     TFLTLEDRTYLEWIKAIIDFYQYDSKCEAISSLENILLKVSSNTLIYLKALNTLSNFY
                     SLVGREQEYEANYSHLIELYQTKNLDHQEFLFGYIRVRYNYAHYLVSKEKYNEAIQEA
                     LETIELCKQRQTSYQLAPLLILVGNAGAKFLDREQVKNYYIEARELCKIYNNPLMLMK
                     IENYLKELDTV"
     gene            1295..1915
                     /locus_tag="VYO11_001940"
     CDS             1295..1915
                     /locus_tag="VYO11_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000839915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1596441.1"
                     /translation="MKSMRILFLLALIQISLSSCFLWKECILSFKQSTAFFIGSMVFV
                     SGICAGVNYLYTRKQEVHSVLASKKSVKLFYSMLLLINLLGAVLVLSDNLFIKNTLQQ
                     ELVDFLLPSFFFLFGLDLLIFLPLKKYVRDFLAMLDRKKTVLVTILATLLFLRNPMTI
                     VSLLIYTGLGLFFAAYLVPNSVKKEVSFYGHIFRDLVLVIVTLIFF"
     gene            2001..2444
                     /gene="tsaE"
                     /locus_tag="VYO11_001941"
     CDS             2001..2444
                     /gene="tsaE"
                     /locus_tag="VYO11_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HEV1596442.1"
                     /translation="MYTKNEEELQALGERLGHLLAKNDVLILIGELGAGKTTFTKGLA
                     KGLQISQMIKSPTYTIVREYEGRLPLYHLDVYRIEGDADSIDLDEFIFGGGVTVIEWG
                     NLLGDALPDAYLELEILKEADGRRLNFQAKGLRAEKLLEELQYGV"
     gene            2434..2952
                     /locus_tag="VYO11_001942"
     CDS             2434..2952
                     /locus_tag="VYO11_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1596443.1"
                     /translation="MEYELLIREAEPKDAAELVAFLNRVSLETDFTSLDGDGILLTSE
                     EMEIFLNKQASSDNQITLLAFLNGKIAGIVNITADQRKRVRHIGDLFIVIGKRYWNNG
                     LGSLLLEEAIEWAQASGILRRLQLTVQTRNQAAVHLYQKHGFVIEGSQERGAYIEEGK
                     FIDVYLMGKLID"
     gene            2960..3976
                     /locus_tag="VYO11_001943"
     CDS             2960..3976
                     /locus_tag="VYO11_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HEV1596444.1"
                     /translation="MVKKIIGMVLALLSVTVVGVGVFAYTIYQQGTETLAKTYKKIGE
                     ETKVIEATEPLTILLMGVDTGNAERTETWVGRSDSMILMTVNPKTKKTTMMSLERDIL
                     TRIESGNGQAHEAKLNSAYADGGAELAIETIQKMMNIHIDRYVMVNMRGLQKLVDAVG
                     GITVNNILGFPISISDQEEFNTISIGVGEQHIGGEEALVYARMRYQDPEGDYGRQKRQ
                     REVIQKVMEKALSLNSVGHYQEILKALSDNMQTNIDLSAKSIPNLLGYKDSFKTIETQ
                     QLQGEGEILQGVSYQIVSRAHMLEMQNILRRSLGQEEVTQLETNAVLFEDLFGRAPVG
                     DEDN"
     gene            4061..5317
                     /locus_tag="VYO11_001944"
     CDS             4061..5317
                     /locus_tag="VYO11_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HEV1596445.1"
                     /translation="MKAEIIAVGTEILTGQIVNTNAQFLSEKLAEIGVDVYFQTAVGD
                     NEVRLLSLLEIASQRSSLVILTGGLGPTEDDLTKQTLAKFLGKALVFDPQAQEKLDIF
                     FALRPDYARTPNNERQAQIVEGAIPLPNETGLAVGGKLEVDGVTYVVLPGPPSELKPM
                     VLNQLLPKLMTGNKLYSRVLRFFGIGESQLVTILADLIDNQIDPTLAPYAKTGEVTLR
                     LSTKASSQEEANQALDILENQILDCQTFEGISLRDFCYGYGEETSLASIVVEELKRQG
                     KTIAAAESLTAGLFQATVANFSGVSSIFEGGFVTYSLEEKSRMLDIPAKNLEEHGVVS
                     EFTAQKMAEQARSKTQSDFGISLTGVAGPDSLEGHPVGTVFIGLAQDQGTEVIKVNIG
                     GRSRADVRHIAVMHAFNLVRKALLSD"
     gene            5372..6538
                     /gene="recA"
                     /locus_tag="VYO11_001945"
     CDS             5372..6538
                     /gene="recA"
                     /locus_tag="VYO11_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HEV1596446.1"
                     /translation="MAKKPKKLEEISKKFGAEREKALNDALKLIEKDFGKGSIMRLGE
                     RAEQKVQVMSSGSLALDIALGSGGYPKGRIIEIYGPESSGKTTVALHAVAQAQKEGGI
                     AAFIDAEHALDPAYAAALGVNIDELLLSQPDSGEQGLEIAGKLIDSGAVDLVVVDSVA
                     ALVPRAEIDGDIGDSHVGLQARMMSQAMRKLGASINKTKTIAIFINQLREKVGVMFGN
                     PETTPGGRALKFYASVRLDVRGNTQIKGTGDQKETNVGKETKIKVVKNKVAPPFKEAV
                     VEIMYGEGISKTGELLKIASDLDIIKKAGAWYSYKDEKIGQGSENAKKYLAEHPEIFD
                     EIDKQVRSKFGLIDGEEVSEQDTENKKDEPKKEEAVNEEVPLDLGDELEIEIEE"
     gene            6845..8215
                     /locus_tag="VYO11_001946"
     CDS             6845..8215
                     /locus_tag="VYO11_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HEV1596447.1"
                     /translation="MNKKRTVDLIHGPILPSLLSFTFPILLSNIFQQLYNTADVLIVG
                     RFLGQESLAAVGATTAIFDLIVGFTLGVGNGMGIVIARYYGARNFTKIKEAVAATWIL
                     GALLSILVMLLGFLGLYPLLQYLDTPAEILPQSYQYISMIVTCVGVSFAYNLFAGLLR
                     SIGDSLAALGFLIFSALVNVVLDLYFITQLHLGVQSAGLATIISQGLSAVLCFYYIRK
                     SVPELLPQFKHFKWDKSLYADLLEQGLAMGLMSSIVSIGSVILQFSVNTFGAVIISAQ
                     TAARRIMTFALLPMTAISASMTTFASQNLGAKRPDRIVQGLRIGSRLSISWAVFVCIF
                     LFFASPALVSFLASSTDGYLIENGSLYLQISSTFYPILSLLLIYRNCLQGLGQKILPL
                     VSSFIELIGKIVFVVLIIPWAGYKGVILCEPLIWVAMTVQLYFSLFRHPLIKEGKAIL
                     ATKVQS"
     gene            8591..>9096
                     /gene="lytA"
                     /locus_tag="VYO11_001947"
     CDS             8591..>9096
                     /gene="lytA"
                     /locus_tag="VYO11_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase LytA"
                     /protein_id="HEV1596448.1"
                     /translation="MEINVSKLRTDLPQVGVQPYRQVHAHSTGNPHSTVQNEADYHWR
                     KDPELGFFSHIVGNGCIMQVGPVDNGAWDVGGGWNAETYAAVELIESHSTKEEFMTDY
                     RLYIELLRNLADEAGLPKTLDTGSLAGIKTHEYCTNNQPNNHSDHVDPYPYLAKWGIS
                     REQFKHDI"
BASE COUNT         2766 a         1542 c         2013 g         2775 t
ORIGIN      
        1 aaaaatttta taatgcaatt aagcaaatag gaaggtttat tatctttaat gaatacactc
       61 gcagagaaat tcagattgaa aagaaaagag ttgagactct cccaacaaac tcttgcagaa
      121 ggaatttgtg aacaaagtca gattagtaaa attgagagag ggcatttcat tccctccgca
      181 gaccttttgt tcaaactctc tcaacgactt gaagtaccat tagattattt ttttaatgaa
      241 caaattgaaa ttaaatctaa cctctctaat ttcaagcaat tgtctgctcg actattagac
      301 gatagaaatt atgataattt ggaatatatt tatagaattg agattgaacg aagtactttt
      361 ctaacactag aagaccgaac ttatcttgaa tggattaaag ctattattga cttctatcaa
      421 tatgacagta agtgtgaggc aatttcttca ttggaaaata tattattaaa agtctcttca
      481 aatactctga tttatttaaa ggcgttgaat actctatcta atttctattc cttagtgggt
      541 cgtgaacaag aatatgaggc aaactactct catttaatag agttgtatca gacaaaaaat
      601 ttggaccatc aagagttttt atttggctac atcagagttc gttacaacta cgctcactac
      661 ctagtatcaa aggaaaaata taatgaagcc atccaagaag ctcttgaaac gattgaactc
      721 tgtaaacaaa gacagacaag ctaccaattg gctcctctac ttattcttgt aggaaatgct
      781 ggagccaaat ttctagacag agaacaagtc aaaaattatt atatagaagc aagagagtta
      841 tgtaagattt ataacaatcc tttaatgttg atgaagatag aaaattattt gaaggaatta
      901 gatactgttt agttaatctt gacattatag tttttctgaa acgttaaata acctgtaagg
      961 ctgatagtta gattaatact atcagcctta tcattatgtg actctgagtc cgtctcgctc
     1021 cgtgaggtgc gagacaaaac aaccacccgt ttgacggatt ttcatgattt caaatttata
     1081 ttcttcgaaa atctcttcaa accacgtcag ctctatctgc aatctcaaaa cactgttttg
     1141 agcaacctgt ggctagctac ctagtttgat ctttgatttt cattgagtat tagtctctag
     1201 tgtttgttta gcgtcttaaa gagacatttg agaagattag aaacagttct ctcttttctc
     1261 ctagtataat gattggtagg aagggagaga gaagatgaaa tcaatgagaa tcttattttt
     1321 gttagcttta attcaaatca gtttgagtag ctgtttccta tggaaggaat gcatcttgtc
     1381 ctttaaacaa agtacagctt ttttcatcgg aagcatggtt ttcgtttcag gaatctgtgc
     1441 tggagtaaat tatctttata cccgtaagca agaagtccat agtgtcctag ccagtaagaa
     1501 gtcggtgaag cttttttaca gtatgttact cttaattaat ttgttaggag ctgttcttgt
     1561 tttgtcagat aacttgttca tcaaaaatac gctgcagcaa gaattagttg actttttatt
     1621 gccatccttc tttttcctat ttgggctaga tttgctgatt tttttaccct tgaaaaaata
     1681 cgtgcgcgat tttcttgcta tgctagacag aaaaaagaca gtgttggtga ctattttagc
     1741 aacacttctt ttcttaagaa atccaatgac cattgtctca cttctgattt atactggact
     1801 gggcttgttt tttgcagcct atcttgtccc aaattcggtt aagaaggaag tttcctttta
     1861 tggtcatatt ttccgagatc ttgtattggt cattgttacg ctcattttct tttagagaaa
     1921 gcctgttttt tatggatgtt atgatgataa gtttagtagg aaaatagaca caaaagaaaa
     1981 gtttttggta taataagagt atgtacacaa aaaatgaaga agagttgcaa gccttagggg
     2041 agcgtttggg ccatctatta gcaaagaatg atgttttaat cttaattgga gaactgggtg
     2101 caggtaaaac gacctttact aaaggacttg caaaaggatt acagatttct caaatgatta
     2161 aaagtcctac ctatactatc gtgagagagt atgaaggtcg acttccactt tatcacctag
     2221 atgtttatcg tattgaagga gatgctgatt ctatcgactt ggatgagttt atctttggtg
     2281 gcggcgtgac tgttattgag tggggaaatc tcttaggaga tgccttgcca gatgcttatt
     2341 tagaattgga aattctaaaa gaagcagatg gacgccgttt aaattttcag gcaaagggtt
     2401 tgcgtgctga gaaattgtta gaggagcttc aatatggagt atgaattgct cattagggaa
     2461 gcagagccca aagatgcagc tgaattagtg gcctttttaa atcgtgtgag tttggagaca
     2521 gactttacca gcctagacgg agatggtatt ctcttgacta gtgaggagat ggaaatattc
     2581 ctcaacaagc aagctagttc ggacaatcag ataaccttac ttgcattctt aaatggcaaa
     2641 attgctggta ttgtaaatat tacagctgac cagcgtaaga gagtccgtca tattggagat
     2701 ctcttcattg tgattggaaa aagatattgg aataatggct tgggaagttt gttgctagaa
     2761 gaagcgatag agtgggcaca agcaagtggc attctgcgtc gtctccaact gactgtccaa
     2821 actcgtaatc aagcagcagt ccatctttat caaaagcatg gctttgtcat tgaaggtagc
     2881 caagagcgtg gggcatatat agaagaaggg aaatttatcg atgtttactt gatgggtaaa
     2941 ctgatagatt agtagaaata tggttaaaaa aattattgga atggtgctag ctttactttc
     3001 tgtaactgta gtaggagtag gtgtttttgc ttatactatt tatcaacaag ggacagaaac
     3061 cttagctaaa acctataaaa aaatcggcga agaaaccaag gttattgaag cgactgaacc
     3121 tctaaccatt ctgttaatgg gagtggacac cggaaatgct gaacgaactg aaacttgggt
     3181 cggtagaagt gatagcatga tcttgatgac agtgaatcct aaaacgaaaa aaacaacaat
     3241 gatgagttta gagcgggata ttctgacgcg cattgaatca gggaatggtc aggctcatga
     3301 agcgaaactg aactcagcat atgcagatgg tggagcagag cttgctatag aaaccattca
     3361 aaaaatgatg aatatccata ttgatcgcta tgtgatggtc aatatgagag ggttgcaaaa
     3421 actagtggat gcagtaggag gtattacagt caataatatc ctaggtttcc caatttctat
     3481 cagtgaccaa gaagaattta atactatttc tatcggtgtt ggggagcaac atattggggg
     3541 agaagaagcc ctagtctatg cacgaatgcg ttaccaagat cctgaggggg attatggtcg
     3601 tcaaaaacgt caacgtgaag ttattcaaaa agtcatggaa aaagctctca gtttaaatag
     3661 cgttggtcat tatcaagaga ttctaaaagc tttgagtgac aatatgcaga ccaatattga
     3721 tttgtctgca aaaagtatcc ctaacttgct aggctataaa gattcattta aaaccattga
     3781 aactcagcag ttgcagggtg aaggagagat acttcaaggt gtttcttacc agattgtttc
     3841 gagagcacat atgttggaaa tgcaaaatat actccgacgt tctttgggac aagaagaagt
     3901 tactcagctt gaaaccaatg cggttttatt tgaagattta tttggcagag cacctgttgg
     3961 tgatgaagat aattaacttt tgatacaaat aaaaaaatca atcgtaggaa aattcctgcg
     4021 attttttcaa aaaaatacga atagataggt aggaggaaac atgaaagcag aaatcattgc
     4081 tgttggaaca gagattttga caggacagat tgtcaacacc aatgcccagt ttttgtcgga
     4141 aaaactagct gagattgggg tagatgtata ttttcagacg gctgtaggag acaatgaagt
     4201 tcgtctcttg tctttgcttg agattgccag tcaacgtagc agtctggtga ttttgacagg
     4261 cggtttgggg ccaactgagg acgacctaac caaacaaacc ctagctaaat ttttagggaa
     4321 agcattagtc tttgatcctc aggctcagga gaagttggat atcttttttg ccctgcgacc
     4381 agactatgcc cgaacaccga ataacgaaag acaagctcaa attgtagaag gagcgattcc
     4441 actgccaaac gaaacaggac tggctgttgg aggaaaatta gaagtagacg gagtgaccta
     4501 tgtcgtcctt ccaggtccgc caagtgaatt gaaacccatg gtcttaaacc aacttctacc
     4561 caagttgatg acagggaaca agctgtattc ccgagttctt cgtttctttg ggattggcga
     4621 gagccagttg gttacgattt tggctgattt aattgataat cagatcgatc ctaccttggc
     4681 cccttatgcc aagacaggag aagtcactct acgtctgtca acaaaggcta gcagtcaaga
     4741 agaggcgaat caagcgctgg atatcttgga aaatcaaatc ttggactgcc agactttcga
     4801 aggaatttct ttacgagact tttgctatgg ttatggggaa gaaactagtt tagccagcat
     4861 tgtggtagaa gaactgaaaa ggcaagggaa aaccatcgcg gctgcagaga gtttgacggc
     4921 aggtcttttc caagctaccg tggcgaattt ttctggagtt tcaagtatat ttgagggtgg
     4981 ttttgtgacc tatagcttgg aggaaaaatc aaggatgttg gatattcctg ccaagaattt
     5041 ggaagaacat ggtgtggtgt ctgaatttac agctcagaag atggctgagc aggcacgaag
     5101 caagacccag tctgattttg gaattagttt gactggagtg gcaggaccag atagcctaga
     5161 aggacaccca gttgggacag tcttcatagg cttggcgcaa gatcaaggaa ctgaggttat
     5221 caaggttaat attggaggca gaagccgagc agatgtacgt cacattgcgg ttatgcatgc
     5281 ctttaaccta gttcgcaagg ctttattaag tgactaactt ttgatataat agtagatagg
     5341 tctgaggatc attagaatgt aggagaatag aatggcgaaa aaaccaaaaa aattagaaga
     5401 aatttcaaaa aaatttgggg cagaacgtga aaaggccttg aatgacgctc ttaaattgat
     5461 tgagaaagac tttggtaaag gatcaatcat gcgtttgggt gaacgtgcgg agcaaaaggt
     5521 gcaagtgatg agctcaggtt ctttagctct tgacattgcc cttggctcag gtggttatcc
     5581 taagggacgt atcatcgaaa tctatggccc agagtcatct ggtaagacaa cggttgccct
     5641 tcatgcagtt gcacaagcgc aaaaagaagg tgggattgct gcctttatcg atgcggaaca
     5701 tgcccttgat ccagcttatg ctgcggccct tggtgtcaat attgacgaat tgctcttgtc
     5761 tcaaccagac tcaggagagc aaggtcttga gattgcggga aaattgattg actcaggtgc
     5821 agttgatctt gtcgtagtcg actcagttgc tgcccttgtt cctcgtgcgg aaattgatgg
     5881 agatatcgga gatagccatg ttggtttgca ggctcgtatg atgagccagg ccatgcgtaa
     5941 acttggcgcc tctatcaata aaaccaaaac aattgccatt tttatcaacc aattgcgtga
     6001 aaaagttgga gtgatgtttg gaaatccaga aacaacaccg ggcggacgtg ctttgaaatt
     6061 ctatgcttca gtccgcttgg atgttcgtgg taatacacaa attaagggaa ctggtgatca
     6121 aaaagaaacc aatgtcggta aagaaactaa gattaaggtt gtaaaaaata aggtagctcc
     6181 accgtttaag gaagccgtag ttgaaattat gtacggagaa ggaatttcta agactggtga
     6241 gcttttgaag attgcaagcg atttggatat tatcaaaaaa gcaggggctt ggtattctta
     6301 caaagatgaa aaaattgggc aaggttctga gaatgctaag aaatacttgg cagagcaccc
     6361 agaaatcttt gatgaaattg ataagcaagt ccgttctaaa tttggcttga ttgatggaga
     6421 agaagtttca gaacaagata ctgaaaacaa aaaagatgag ccaaagaaag aagaagcagt
     6481 gaatgaagaa gttccgcttg acttaggcga tgaacttgaa atcgaaattg aagaataagc
     6541 tgttaaagca gtggagaaat ccgctacttt ttcgattttt gattcaagtt tttagattat
     6601 atatagtagc ttgaaataag atatgaacaa ctttattagg aaagtcaaat taatttctag
     6661 aaatgtttta gcagctacag cgtactattc caaactcaac caactataat agatcgaaac
     6721 tagaatagta cacatctact tctaaaacat tgttaaaaat cgatttgact gtccttattt
     6781 cattccgcta tatataagtt tgctgtttct tgtcgctcct ctggaaagct gatataatag
     6841 ctttatgaat aaaaaacgaa cagtggacct gatacatggt ccgattcttc cctcgctctt
     6901 aagcttcacc tttccaatct tgctatcaaa tatttttcaa cagctctata acactgctga
     6961 tgtcttgatt gttggacgat ttcttggtca agaatccttg gctgcagtag gagcgacgac
     7021 agcgattttt gacctgattg taggctttac acttggtgtt ggcaatggca tggggattgt
     7081 cattgctcgt tattatgggg ctcggaattt cactaaaatc aaggaagcag tagcagccac
     7141 ctggatttta ggtgctcttt tgagcattct agttatgttg ctgggctttc ttggcttgta
     7201 tcctctcttg caatacttag atactcctgc agaaattctt cctcaatctt atcaatatat
     7261 ttctatgatt gtgacctgtg taggtgtcag ctttgcttat aatctttttg caggcttgtt
     7321 gcggtctatt ggtgacagtc tagcagccct gggatttctg attttctctg ccttggttaa
     7381 tgtggttctg gatctctatt ttattacgca attgcatctg ggagttcaat ccgcaggact
     7441 tgctaccatt atttcgcaag gtttatcagc ggttctctgc ttttattata ttcgtaaaag
     7501 tgtgccagaa ctcttgccac agtttaaaca tttcaaatgg gacaaaagct tgtacgcgga
     7561 tctcttggag caaggtttgg ctatgggctt gatgagttca attgtatcta tcggcagtgt
     7621 gattttacag ttttctgtta atacatttgg tgcagtgatt attagtgccc agacggcagc
     7681 tcgacgcatt atgacctttg cccttcttcc tatgaccgct atttctgcat caatgacgac
     7741 ctttgcttct cagaatctag gagctaagcg acctgaccgt attgttcaag gtcttcgaat
     7801 cggcagtcgt ttaagtatat cctgggcagt ttttgtttgt attttcctct tttttgccag
     7861 tccagctttg gtttccttct tggctagttc gacagatggt tacttgatag aaaatggaag
     7921 tctctatctg caaatcagtt caacctttta tcccattttg agcctcttgt tgatttatcg
     7981 caattgcttg cagggcttgg ggcaaaagat ccttcctcta gtttctagct ttattgaact
     8041 aatcggaaaa atcgtttttg tggttttgat tattccttgg gcaggatata agggtgttat
     8101 cctttgtgaa cctcttatct gggttgccat gacagttcaa ctgtacttct cattattccg
     8161 tcatcccttg ataaaagaag gcaaggcaat cttggcaacc aaagtgcaat cctagttgga
     8221 tttactgaat aaaatccatt tcctctagtg aaaatcgaaa aaacttgtgt tctcgtcttt
     8281 agtttggtgt tgaaaatagt ttaacagact tttgacttct tttatatgat ataataaagt
     8341 atagtattta tgaaaaggac atatagagac tgtaaaaata tacttttgaa aagcttttta
     8401 gtctggggtg ttattgtaga tagaatgcag accttgtcag tcctatttac agtgtcaaaa
     8461 tagtgcgttt tgaagttcta tctacaagcc taatcgtgac taagattgtc ttctttgtaa
     8521 ggtagaaata aaggagtttc tggttctgga ttgtaaaaaa tgagttgttt taattgataa
     8581 ggagtagaat atggaaatta atgtgagtaa attaagaaca gatttgcctc aagtcggcgt
     8641 gcaaccatat aggcaagtac acgcacactc aactgggaat ccgcattcaa ccgtacagaa
     8701 tgaagcggat tatcactggc ggaaagaccc agaattaggt tttttctcgc acattgttgg
     8761 gaacggttgc atcatgcagg taggacctgt tgataatggt gcctgggacg ttgggggcgg
     8821 ttggaatgct gagacctatg cagcggttga actgattgaa agccattcaa ctaaagaaga
     8881 gttcatgacg gactaccgcc tttatatcga actcttacgc aatctagcag atgaagcagg
     8941 tttgccgaaa acgcttgata cagggagttt agctggaatt aaaacgcacg agtattgcac
     9001 gaataaccaa ccaaacaacc actcagacca tgtggatcca tacccttact tggcaaaatg
     9061 gggcattagc cgtgagcagt ttaagcatga tattga
//
LOCUS       DAVLXH010000073         8992 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00028199
            SAMN33607166-rid17955573.denovo.074, whole genome shotgun sequence.
ACCESSION   DAVLXH010000073 DAVLXH010000000
VERSION     DAVLXH010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607166
            Sequence Read Archive: SRR23725544
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8992)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8992)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721421.1
            Genome Coverage       :: 115x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:42:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,210
            CDSs (total)                      :: 2,161
            Genes (coding)                    :: 2,023
            CDSs (with protein)               :: 2,023
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 73 of 138
            Pseudo Genes (incomplete)         :: 60 of 138
            Pseudo Genes (internal stop)      :: 40 of 138
            Pseudo Genes (multiple problems)  :: 31 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8992
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607166-rid17955573.denovo.074"
                     /strain="AUSMDU00028199"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1349"
     gene            complement(296..1144)
                     /gene="dprA"
                     /locus_tag="VYO11_001948"
     CDS             complement(296..1144)
                     /gene="dprA"
                     /locus_tag="VYO11_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HEV1596449.1"
                     /translation="MKITNYEIYKLKKSGLTNQQILKVLEYGENVDQELLLGDIADIS
                     GCRNPAVFMERYFQIDDAHLSKEFQKFPSFSILDDCYPWDLSEIYDAPVLLFYKGNLD
                     LLKFPKVAVVGSRACSKQGAKSVEKVIQGLENELVIVSGLAKGIDTAAHMAALQNGGK
                     TIAVIGTGLDVFYPKANKRLQDYIGNDHLVLSEYGPGEQPLKFHFPARNRIIAGLCRG
                     VIVAEAKMRSGSLITCERAMEEGRDVFAIPGSILDGLSDGCHHLIQEGAKLVTSGQDV
                     LAEFEF"
     gene            complement(1250..1939)
                     /locus_tag="VYO11_001949"
     CDS             complement(1250..1939)
                     /locus_tag="VYO11_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NTP transferase domain-containing protein"
                     /protein_id="HEV1596450.1"
                     /translation="MKAIILAAGLGTRLRPMTENTPKALVQVNQKPLIEYQIEFLKEK
                     GINDIIIIVGYLKEQFDYLKEKYGVRLVFNDKYADYNNFYSLYLVKEELANSYVIDAD
                     NYLFKNMFRNDLTRSTYFSVYREDCTNEWFLVYGDDYKVQDIIVDSKAGRILSGVSFW
                     DAPTAEKIVSFIDKAYASGEFVDLYWDNMVKDNIKELDVYVEELEGNSIYEIDSVQDY
                     RKLEEILKNEN"
     gene            complement(1951..2829)
                     /locus_tag="VYO11_001950"
     CDS             complement(1951..2829)
                     /locus_tag="VYO11_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HEV1596451.1"
                     /translation="MKSKNGVPFGLLSGIFWGLGLTVSAYIFSIFTDLSPFVVAAAHD
                     FLSIFILLAFLLVKEGKVRLSIFLNIRNVSVIIGALLAGPIGMQANLYAVKYIGSSLA
                     SSVSAIYPAISVLLAFFFLKHKISKNTVFGIVLIIGGIIAQTYKVEQVNSFYIGILCA
                     LVCAIAWGSESVLSSFAMESELSEIEALLIRQVTSFLSYLVIVLFSHQSFTAVANGQL
                     LGLMIVFAAFDMISYLAYYIAINRLQPAKATGLNVSYVVWTVLFAVVFLGAPLDMLTI
                     MTSLVVIAGVYIIIKE"
     gene            complement(2819..3688)
                     /gene="licA"
                     /locus_tag="VYO11_001951"
     CDS             complement(2819..3688)
                     /gene="licA"
                     /locus_tag="VYO11_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline kinase LicA"
                     /protein_id="HEV1596452.1"
                     /translation="MEKIIKEKISSLLSQEEEVLSVEQLGGMTNQNYLAKTTNKQYIV
                     KFFGKGTEKLINRQDEKYNLELLKDLGLDVKNYLFDIEAGIKVNEYIESAITLDSTSI
                     KTKFDKIAPILQTIHTSAKELRGEFAPFEEIKKYESLIEEQIPYANYESVRNAVFSLE
                     KRLADLGVDRKSCHIDLVPENFIESPQGRLYLIDWEYSSMNDPMWDLAALFLESEFTS
                     QEEETFLSHYESDQTPVSHEKIAIYKILQDTIWSLWTVYKEEQGEDFGDYGVNRYQRA
                     VKGLASYGGSDEK"
     gene            complement(3705..4727)
                     /locus_tag="VYO11_001952"
     CDS             complement(3705..4727)
                     /locus_tag="VYO11_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HEV1596453.1"
                     /translation="MINQIYQLTKPKFINVKYQEEAIDQENHILIRPNYMAVCHADQR
                     YYQGKRDPKILNKKLPMAMIHESCGTVISDPTGTYEVGQKVVMIPNQSPMQSDEEFYE
                     NYMTGTHFLSSGFDGFMREFVSLPKDRVVAYDAIEDTVAAITEFVSVGMHAMNRLLTL
                     AHSKRERIAVIGDGSLAFVVANIINYTLPESEIVVIGRHWEKLELFSFAKECYITDNI
                     PEELAFDHAFECCGGDGTGPAINDLIRYIRPQGTILMMGVSEYKVNLNTRDALEKGLI
                     LVGSSRSGRIDFKNAIQMMEVKKFANRLKNILYLEEPVREIKDIHRVFATDLNTAFKT
                     VFKWEV"
     gene            complement(4732..5439)
                     /locus_tag="VYO11_001953"
     CDS             complement(4732..5439)
                     /locus_tag="VYO11_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /protein_id="HEV1596454.1"
                     /translation="MIYAGILAGGTGTRMGISNLPKQFLELGDRPILIHTIEKFVLEP
                     SIEKIVVGVHGDWVSHAEDLVDKYLPLYKERIIITKGGADRNTSIKKIIEAIDAYRPL
                     TPEDIVVTHDSVRPFITLRMIQDNIQLAQNHDAVDTVVEAVDTIVESTNGQFITDIPN
                     RAHLYQGQTPQTFRCKDFVDLYGSLSDEEKEILTDACKIFVIKGKDVALAKGEYSNLK
                     ITTVTDLKIAKSMIEKD"
     gene            5775..7262
                     /gene="tacF"
                     /locus_tag="VYO11_001954"
     CDS             5775..7262
                     /gene="tacF"
                     /locus_tag="VYO11_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV teichoic acid flippase TacF"
                     /protein_id="HEV1596455.1"
                     /translation="MKSIKLNALSYMGIRVLNIIFPILTGTYVARVLDRTDYGYFNSV
                     DTILSFFLPFATYGVYNYGLRAISNVKDNKKDLNRTFSSLFYLCIACTILTTAVYILA
                     YPLFFIDNPIVKKVYLVMGIQLIAQIFSIEWVNEALENYSFLFYKTAFIRILMLVSIF
                     LFVKNEHDIVVYTLVMSLSTLINYLISYFWIKRDIKLVKIHLSDFKPLFLPLTAMLVF
                     ANANMLFTFLDRLFLVKTGIDVNVSYYTIAQRIVTVIAGVVTGAIGVSVPRLSYYLGK
                     GDKEAYVSLVNRGSRIFNFFIIPLSFGLMVLGPNAILLYGSEKYIGGGILTSLFAFRT
                     IILALDTILGSQILFTNGYEKRITVYTVFAGLLNLGLNSLLFFNHIVAPEYYLLTTML
                     SETSLLVFYIIFIHRKQLIHLGHIFSYTVRYSLFSLSFVAIYFLINFVYPVDMVINLP
                     FLINTGLIVLLSAISYISLLVFTKDSIFYEFLNHVLALKNKFKKS"
     gene            7272..8075
                     /locus_tag="VYO11_001955"
     CDS             7272..8075
                     /locus_tag="VYO11_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HEV1596456.1"
                     /translation="MKQLTVEDAKQIELEILDYIDTLCKKHNINYIINYGTLIGAVRH
                     EGFIPWDDDIDLSMPREDYQRFINIFQKEKSKYKLLSLETDKNYFNNFIKITDSTTKI
                     IDTRNTKTYESGIFIDIFPIDRFDDPKVIDTCYKLESFKLLSFSKHKNIVYKDSLLKD
                     WIRTAFWLLLRPVSPRYFANKIEKEIQKYSRENGQYMAFIPSKFKEKEVFPSGTFDKT
                     IDLPFENLSLPAPEKFDTILTQFYGDYMTLPPEEKRFYSHEFHAYKLED"
     gene            8077..8886
                     /locus_tag="VYO11_001956"
     CDS             8077..8886
                     /locus_tag="VYO11_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HEV1596457.1"
                     /translation="MQYLEKKEIKEIQLALLDYIDETCKKYDIPYFLSYGTMLGAIRH
                     KGMIPWDDDIDISLYREDYERLLKIIEEENHPRYKVLSYDTSSWYFHNFASILDTSTV
                     IEDHVKYKRHDTSLFIDVFPIDRFTDLSIVDKSYKYVALRQLAYIKKSRAVHGDSKLK
                     DFLRLCSWYALRFVNPRYFYKKIDQLVKNAVTNTPQYEGGVGIGKEGMKEIFPVDTFK
                     ELILTEFEGRMLPVPKKYDQFLTQMYGDYMTPPSKEMQEWYSHSIKAYRKN"
BASE COUNT         2826 a         1815 c         1513 g         2838 t
ORIGIN      
        1 tcactatact ttcccttata ctcaatgaaa atcaaagcac tgctttgagg ttgtagataa
       61 gactgacgaa gtcagctcaa aatactgttt tgaggttgca gatggaagct gacgtagttt
      121 gaagagattt tcgaagagta ttatatgaga aaaatcctct actctactaa tccacttaga
      181 aaaaacgcat attatcaagt gttaaaaact tgctaatatg cgttttatta tggaaatgtt
      241 gggttcattt tctcttaaaa ttgatttttt cttagaattc tagcttaggt catttttaaa
      301 attcaaattc cgcaagaaca tcttgcccac tggtgaccaa ttttgctcct tcttgaatca
      361 aatgatggca accgtctgat agtccatcta aaatgctacc aggaatagca aagacatcgc
      421 gtccttcttc cattgctcgc tcacacgtaa tgagactacc tgaacgcatc ttagcctctg
      481 ctacaatcac accacgacaa agtccagcaa tgatgcgatt acgggcagga aaatgaaatt
      541 tcagaggttg ttcgccaggt ccatattcac ttagaaccag atggtcattg ccgatgtagt
      601 cttgcaagcg tttattggct ttaggataaa acacatccag tcctgttcca atcactgcaa
      661 tggtttttcc gccattctga agagctgcca tatgagctgc tgtgtcaatg cccttggcca
      721 gaccactgac aataaccagt tcattttcca agccttgaat gactttttca actgacttag
      781 ctccctgttt gctacaagca cgactgccca cgaccgctac cttcgggaat ttcaggaggt
      841 caagatttcc cttgtaaaat aaaagtacag gcgcatcata tatttcactc aaatcccaag
      901 gataacagtc atctaaaata gagaaagatg gaaatttttg aaactctttc gacaaatgcg
      961 catcgtctat ctgaaaataa cgttccataa aaacggctgg attacggcaa cctgatatat
     1021 ctgcaatatc acccaacaaa agctcctgat caacattttc accgtattct agcactttca
     1081 aaatctgttg attggtcaaa cctgattttt ttaacttata gatttcatag tttgtgattt
     1141 tcataaataa ctccatttct ttttctactc atctatctat tcgtaaaagt tcgtaaaagt
     1201 tcgtaaaaaa tcaaaaaaca tccgactatt ttgccagatg ttggaatctt taattttcgt
     1261 ttttaagaat ttcttctaat ttacgatagt cttggacact atcgatctca taaatgctat
     1321 tgccttctaa ttcttcaaca tagacatcta gctctttgat attatcctta accatattgt
     1381 cccaatagag atcaacaaat tcaccacttg cataagcctt gtcgataaag ctgacaatct
     1441 tttctgcagt tggagcatcc cagaaggata caccactaag gatgcgacct gccttgctat
     1501 caacaataat gtcttgaacc ttgtagtcat ctccatagac caagaaccat tcgttggtac
     1561 aatcttcacg ataaacacta aaataagtcg aacgtgtcaa atcattgcgg aacatatttt
     1621 taaagagata attgtcagca tcaataacat agctgttggc caattcttct tttacaagat
     1681 agagagagta aaagttattg tagtcagcgt atttatcatt gaaaacgagg cgaacaccgt
     1741 atttttcttt taagtaatcg aattgttctt taagataacc aacaatgatg atgatgtcat
     1801 tgattccttt ttctttgaga aactcaattt ggtattcaat caaaggtttt tgattaacct
     1861 gaaccaaggc tttaggggta ttttcagtca taggacgcaa gcgagttccc aatcccgctg
     1921 ctaagataat ggctttcaca cgaatctcct ttattcttta ataataatat aaactccagc
     1981 aatgacgaca agtgacgtca taatggtcag catatctagc ggtgcaccca aaaaaacaac
     2041 tgcaaacaag accgtccata ctacatagct cacgttcaag cctgtagcct tggctggttg
     2101 caagcgattg atagcgatat aataagccaa gtaggaaatc atatcaaagg ctgcaaaaac
     2161 aatcatgaga cctagcaatt gtccattggc tactgcagta aatgactgat gagagaagag
     2221 cacaatcaca agataggaca agaacgaagt cacttgacgg attaagaggg cttcgatttc
     2281 actcagttca ctttccatag caaaggagct aagaacactc tcacttcccc atgcaatagc
     2341 acaaaccaaa gcacagagaa tcccaatgta gaaggaatta acctgttcaa ccttataggt
     2401 ctgggcaata atccctccaa taatcaagac aatcccaaat acagtatttt tcgaaatctt
     2461 gtgcttcaaa aagaagaaag ccaatagaac tgaaatcgca gggtaaatag ccgatacaga
     2521 tgaagctaaa gaacttccga tatacttaac tgcataaaga ttggcctgca taccgatagg
     2581 gcctgctagc aaggctccga tgataacact gacattgcga atatttaaga aaattgagag
     2641 gcgaactttc ccttctttta ccaagagaaa agctagtaag ataaagatgc tcaaaaaatc
     2701 atgagctgca gccaccacaa agggtgacaa atctgtaaaa atcgaaaaga tataagcact
     2761 aaccgttaga cccaagcccc agaaaatacc tgagagaagg ccaaaaggaa ctccgttttt
     2821 acttttcatc tgaacctcca taagaagcca aacctttaac agctctttgg taacgattca
     2881 caccatagtc accaaaatct tcaccttgct cttccttata gacagtccat agactccaaa
     2941 tagtatcttg taaaatttta taaatagcaa tcttttcatg agaaaccggt gtttggtcac
     3001 tctcatagtg agataagaaa gtttcttcct cttgggaagt gaattcagac tctaaaaaga
     3061 gggcagccaa atcccacatt ggatcattca ttgatgaata ttcccagtca atcaaataaa
     3121 gtcgtccttg aggtgattcg ataaagtttt caggcaccaa atcgatatga caagattttc
     3181 tgtcaacacc taagtcagcc agtcttttct ctaaggagaa gactgcattt ctaacagatt
     3241 catagttggc ataaggaatt tgttcttcaa tcaaggattc gtattttttg atttcttcaa
     3301 aaggagcaaa ttctcctctt aattccttag cagacgtatg aatagtttgt aatattggag
     3361 caattttgtc gaacttggtc ttgattgacg ttgaatcaag cgtaatcgca gattcgatat
     3421 actcatttac tttgatacca gcttcaatat caaaaagata attttttaca tctaagccta
     3481 aatcctttag tagttcaaga ttgtactttt catcttgtcg attgataagc ttttctgtcc
     3541 ctttaccaaa gaatttaaca atgtattgct tatttgttgt tttggccaaa tagttttgat
     3601 tggtcattcc acccagttgt tcaacactga ggacttcctc ttcttgacta agtaaggaag
     3661 aaattttttc tttaatgatt ttctccacaa ttaacctcca gtacttatac ttcccactta
     3721 aacactgttt taaaggctgt gtttaaatcg gttgcaaaga cacgatgaat atctttaatt
     3781 tctcttacag gttcttctag ataaaggata tttttaagac gattggcaaa tttcttgact
     3841 tccatcattt ggatagcatt tttaaaatca atgcgaccag aacgagatga cccaaccaaa
     3901 atcaagccct tttctaaggc atcgcgagta ttgagattga ctttatattc gctaactccc
     3961 atcatgagaa tcgttccctg aggacgaatg tagcgaatca agtcattaat agctggtcca
     4021 gtaccatcac caccacaaca ttcaaaagca tggtcaaagg ccaactcttc aggaatatta
     4081 tccgtaatat agcattcttt ggcaaatgag aagagttcca acttttccca atgacgacca
     4141 ataaccacaa tctctgattc tggcaaagta tagttgataa tattggcaac cacaaaagct
     4201 aaacttccat ctccaataac ggcgatccgc tcccgcttgc tatgagcaag agtcaataga
     4261 cgattcatag cgtgcatgcc cacactgaca aactctgtaa tggctgcaac cgtatcttca
     4321 atagcatcat aagccaccac acgatcttta gggagagaaa caaactctct cataaagcca
     4381 tcaaatccac tagacaagaa atgggtccct gtcatgtagt tttcatagaa ttcttcatca
     4441 ctctgcatag gagactgatt gggaatcatg acaacttttt gaccaacctc gtaggttccg
     4501 gtcgggtcag aaatgacggt tccacatgac tcgtgaatca ttgccattgg aagcttttta
     4561 ttcaaaatct tgggatcacg ttttccctga tagtaacgct gatccgcatg acagacagcc
     4621 atgtagttgg gacggataag gatatgattc tcttggtcaa tagcctcttc ctgatatttg
     4681 acattgataa acttaggctt agttagttga taaatttgat taatcatttt actagtcttt
     4741 ctcaatcata ctttttgcaa tcttcaaatc tgttacggtt gtaatcttca gatttgagta
     4801 ttcacctttg gccaaggcca catcttttcc tttgatcaca aagattttac atgcatctgt
     4861 caagatttcc ttctcttcat cagaaagaga tccataaagg tccacgaagt ccttgcaacg
     4921 gaatgtttga ggtgtttgtc cttgataaag gtgagcacga tttggaatat ctgtaataaa
     4981 ttgaccattg gtactttcaa cgatagtatc aactgcttct accactgtgt ccactgcgtc
     5041 atgattttgg gcaagttgga tattgtcctg aatcatgcga agtgtaataa atggacgaac
     5101 agaatcgtgg gtaacaacga tatcctctgg agtaagcgga cgataagcat caatggcttc
     5161 aatgattttc ttaatacttg tattgcggtc agcaccaccc tttgtaatga tgatacgttc
     5221 cttataaaga ggaagatatt tatctacaag atcttctgca tgagaaaccc agtctccatg
     5281 aacaccaact acaatttttt caatacttgg ctccaagaca aatttttcaa ttgtatgaat
     5341 caaaataggt cgatcaccta gctctaaaaa ttgttttggc aagttactga tccccatgcg
     5401 tgtgccagtt ccaccggcaa gaattcctgc ataaatcatc tattttctcc tttgtcttac
     5461 taaaaaaact tattctctct attataccac aatctagtcc tatcataaaa gaaatactgg
     5521 tcctcccctt ctagaatagg agaattatgc agttctatta ttcaaagaaa ctagtccatt
     5581 tctagtaatg actaggaatt ctgtagcaat tactaataaa tggctgcgaa attttagagt
     5641 ccttcagaat aatatacttt ccttaaagaa aacttaaaac ttaagatttg aaacttcaaa
     5701 gtgattactt gacttactgc ccttcatttc ttattagcta actttatgat ataatgaaaa
     5761 acgaggtaaa ttgaatgaaa agtataaaat taaatgctct atcttacatg ggaattcgtg
     5821 tcttgaatat tatttttccc atcctaactg gaacctatgt cgcgcgtgtc ttggaccgaa
     5881 ctgactatgg ttacttcaac tcagtcgaca ctattttgtc atttttcttg ccctttgcaa
     5941 cttatggtgt ctataactac ggtttaaggg ctatcagtaa tgtcaaggat aacaaaaaag
     6001 atcttaacag aaccttttct agtctttttt atttgtgcat cgcttgtacg attttgacca
     6061 ctgctgtcta tatcctagcc tatcctctct tctttattga taatccaatc gtcaaaaagg
     6121 tctaccttgt tatggggatt caactcattg cccagatttt ttcaatcgaa tgggtcaatg
     6181 aagctctgga aaattacagt tttctctttt acaaaactgc cttcatccgt atcctgatgc
     6241 tggtctctat tttcttattt gttaaaaatg aacacgatat tgttgtctat acacttgtga
     6301 tgagtttatc gacgctgatt aactacctga ttagttattt ttggattaaa agagacatca
     6361 aacttgttaa gattcaccta agtgatttta aaccactctt tctccctctg acagccatgt
     6421 tagtctttgc caatgccaat atgctcttca cttttttaga tcgcctcttc ctcgttaaaa
     6481 cagggattga tgtcaacgtt agttactata ccatagctca gcgaattgtg accgttatag
     6541 ctggggttgt aacaggtgca attggagtga gtgtgcctcg tctcagttac tatctgggga
     6601 aaggagacaa agaagcctat gtttctctgg ttaatagagg tagtcgaatc tttaacttct
     6661 ttatcattcc actgagtttt ggactcatgg ttttaggacc aaatgccatc ctactttacg
     6721 gtagtgaaaa atatatcgga ggcggcatct tgacctctct cttcgctttt cgtacgatta
     6781 tcctggcctt agataccatt cttggttccc aaattctctt taccaatggc tatgaaaaac
     6841 gtatcacagt ctatacagtc tttgctgggc tactcaattt gggcttgaat agtctcctct
     6901 ttttcaacca tatcgtggct cctgaatact acttactgac aactatgtta tcagagactt
     6961 ctctacttgt tttctatatc attttcatcc atagaaaaca actcatccac ttgggacata
     7021 tctttagcta tactgttcga tactctctct tttcactttc ctttgtagca atttatttcc
     7081 tgattaattt cgtgtatcct gtggatatgg tcattaattt gccatttttg attaatactg
     7141 gtttgattgt cttgctatca gctatctctt atattagtct acttgtcttc acaaaagata
     7201 gcattttcta tgaattttta aaccatgtcc tagccttaaa aaataaattt aaaaaatcat
     7261 aggagtttaa aatgaaacaa ctaaccgttg aagatgccaa acaaattgaa ttagaaattt
     7321 tggattatat tgatactctc tgtaaaaagc acaatatcaa ctatattatt aactacggta
     7381 ctctgattgg ggcggttcga catgagggct ttatcccttg ggacgacgat attgatttat
     7441 ccatgcctag agaagactac caacgattta ttaacatttt tcaaaaggaa aaaagcaagt
     7501 ataagctcct atccttagaa actgataaga actactttaa caactttatc aagataaccg
     7561 acagtacgac taaaattatt gatactcgaa atacaaaaac ctatgagtct ggtatcttta
     7621 tcgatatttt ccctatagat cgctttgatg atcctaaggt cattgatact tgttataaac
     7681 tggaaagctt caaactgctg tctttcagta aacataaaaa tattgtctat aaggatagcc
     7741 ttttaaaaga ttggatacga acagccttct ggttactcct tcgaccggtt tctcctcgtt
     7801 attttgcaaa taaaatcgag aaagaaattc aaaaatatag tcgtgaaaat gggcaatata
     7861 tggcttttat cccttcaaaa tttaaggaaa aggaagtctt cccaagtggt acctttgata
     7921 aaacaatcga tttacccttt gagaatttaa gccttcctgc acctgaaaaa tttgatacta
     7981 ttttgacaca attttatgga gattatatga ccctaccacc agaagaaaaa cgcttctaca
     8041 gtcatgaatt tcacgcttat aaattggagg attaggatgc aatatttaga aaaaaaagaa
     8101 attaaagaaa ttcaactagc cctgctggac tatattgatg agacttgtaa gaaatatgat
     8161 attccttatt ttctcagtta tggaaccatg cttggagcca tccgccacaa aggtatgatt
     8221 ccttgggatg atgatattga tatttccctt tatcgtgagg attatgagcg tttactgaag
     8281 attattgaag aagaaaatca ccctcgctac aaggttcttt cctacgatac atcttcttgg
     8341 tacttccata atttcgcatc gattttggac acttctactg ttatagaaga ccatgttaag
     8401 tacaagcgtc atgataccag ccttttcatc gatgtcttcc caattgatcg atttacagac
     8461 ttgagcattg tcgacaagag ctataagtat gtggctcttc gtcaactagc ttatatcaaa
     8521 aaatcacgag cagttcacgg tgatagcaaa ctaaaagatt ttcttagatt atgtagctgg
     8581 tacgctctcc gatttgtcaa tcctcgctac ttttacaaga aaattgatca actagtcaaa
     8641 aatgctgtaa ccaacactcc tcaatatgaa ggaggagttg ggatcggtaa ggaagggatg
     8701 aaagaaatct tcccagttga tacctttaaa gaactgattt taactgagtt tgagggccgt
     8761 atgttgcctg ttcccaaaaa atatgaccaa tttttaaccc agatgtatgg cgattatatg
     8821 acaccaccat caaaagaaat gcaagagtgg tatagtcata gcattaaagc ttatcgcaaa
     8881 aactgattga ggggtattat acaaactact aagatagagg ttattcaaaa acataatttt
     8941 agtagaaaat gaaatacata ttcccacaat aaaacgcatc atatcaaggt tt
//
LOCUS       DAVLXH010000074         8095 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00028199
            SAMN33607166-rid17955573.denovo.075, whole genome shotgun sequence.
ACCESSION   DAVLXH010000074 DAVLXH010000000
VERSION     DAVLXH010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607166
            Sequence Read Archive: SRR23725544
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8095)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8095)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721421.1
            Genome Coverage       :: 115x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:42:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,210
            CDSs (total)                      :: 2,161
            Genes (coding)                    :: 2,023
            CDSs (with protein)               :: 2,023
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 73 of 138
            Pseudo Genes (incomplete)         :: 60 of 138
            Pseudo Genes (internal stop)      :: 40 of 138
            Pseudo Genes (multiple problems)  :: 31 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8095
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607166-rid17955573.denovo.075"
                     /strain="AUSMDU00028199"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1349"
     gene            106..270
                     /locus_tag="VYO11_001957"
     CDS             106..270
                     /locus_tag="VYO11_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEV1596458.1"
                     /translation="MGIIANVFAGLVGAYAGQSLLGSWGPSIAGMALLPSIVGAAIVI
                     TVVSFFTGRK"
     gene            354..920
                     /gene="amaP"
                     /locus_tag="VYO11_001958"
     CDS             354..920
                     /gene="amaP"
                     /locus_tag="VYO11_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HEV1596459.1"
                     /translation="MSKAKKICFIIFCILILTIFLPVLIDYHQVSDLGIHLLSWRQNS
                     VVEFYLARYVFWGTVVLSTLVLLSILVVMFYPKRYLEIQLETKNDTLKLKNSAIEGFV
                     RSLVSDHRLIKNPTVHVNLRKNKCFVHVEGKILPSDNIADRCQIIQNEITNGLKQFFG
                     IERQVKLEVAVKNYQPKPQNKKTVSRVK"
     gene            932..1102
                     /locus_tag="VYO11_001959"
     CDS             932..1102
                     /locus_tag="VYO11_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HEV1596460.1"
                     /translation="MEWLKQYRYPIIAGLIGVFLACLIVSFGFFKTIFVLILGALGVA
                     AGLYIEKNYIDK"
     gene            1141..1749
                     /locus_tag="VYO11_001960"
     CDS             1141..1749
                     /locus_tag="VYO11_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEV1596461.1"
                     /translation="MSNEKNTNTNVEKKDATVVAHEIKGELTYEDKVIQKIIGLSLEN
                     VSGLLGIDGGFFSNLKEKIVNSDDVTSGVNVEVGKTQVAVDLNVIVEYQKNVPALYSE
                     IREIVSSEVAKMTDLEIVEINVNVVDIKTKEQHEADSVSLQDRVSDVAESTGEFTSEQ
                     FEKAKSGLGSGFSTVQEKVSEGVEAVKGAANGVVSHENTRVN"
     gene            1780..1983
                     /locus_tag="VYO11_001961"
     CDS             1780..1983
                     /locus_tag="VYO11_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HEV1596462.1"
                     /translation="MSVEEKLNQAKGSIKEGVGKAIGDEKMEKEGAAEKVVSKVKEVA
                     EDAKDAVEGAVEGVKNMLSGDDK"
     gene            complement(2094..2366)
                     /locus_tag="VYO11_001962"
                     /pseudo
     CDS             complement(2094..2366)
                     /locus_tag="VYO11_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514870.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            2675..2962
                     /locus_tag="VYO11_001963"
     CDS             2675..2962
                     /locus_tag="VYO11_001963"
                     /inference="COORDINATES: protein motif:HMM:NF033563.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HEV1596463.1"
                     /translation="MIVSLKTKSRKAKDMAESIQGWLAQFLVNLFKSITFDCGKEFSK
                     WKDISNHHDSESFFANLGCPRQRCLNEHSNRLLRCHDLPKQTDFNEVSQEF"
     gene            complement(3240..4010)
                     /locus_tag="VYO11_001964"
     CDS             complement(3240..4010)
                     /locus_tag="VYO11_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HEV1596464.1"
                     /translation="MVEIIYFLIIIIASGLGSISGMGGGIIIKPLMDSFGYHSVSDIA
                     FYSSFSVFIMAIISTIKRFSQSKEIKWRLIFTVSFSSVLGGFLGHLIFQVLLSQLSVR
                     LVSIVQMILLFVMLLVSFVLTDFKKTYQFDKIGFYMICGLLLGLISSFLGIGGGPLNV
                     SLLMVFFSISIKEATMYSLAIIFFSQLSHLATIVVVTGLNQYHLAPVPVIFLASICGG
                     VLGTVVSKVLPENWVRYCFKGMLFFVMGMTLYNLFHIL"
     gene            complement(4025..4651)
                     /locus_tag="VYO11_001965"
                     /pseudo
     CDS             complement(4025..4651)
                     /locus_tag="VYO11_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782422.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="SUMF1/EgtB/PvdO family nonheme iron enzyme"
     gene            complement(4557..5159)
                     /locus_tag="VYO11_001966"
     CDS             complement(4557..5159)
                     /locus_tag="VYO11_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEV1596465.1"
                     /translation="MNTMLDKMQEKLSPIAMKVGNQKFLVALRDSFVGTMPVIMTGSI
                     ALLLNAFLVDLPQQFHLESITKTFQWLVDINNLVFKGSIPIVSLLFIYCLEVNIAKIY
                     KVDTVSAGLVSLASFVISIGSTVTKSFPLANVGDVKLDQILQGIDNLAFDGKNLMVTI
                     GNVIPGNHINARGRKGGISSSCWDSVVVTSSERLLETSLR"
     gene            complement(5169..5486)
                     /locus_tag="VYO11_001967"
     CDS             complement(5169..5486)
                     /locus_tag="VYO11_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEV1596466.1"
                     /translation="MDESNLESVMGLIMYGGDAKSNAMEAIQAAKKGDFSKANRRLAD
                     ANAALLQAHKAQTEMLTKEAQGEETSISLLMVHAQDHLMTSLTFVDLAKEVVEVYERF
                     EKN"
     gene            complement(5503..5820)
                     /locus_tag="VYO11_001968"
     CDS             complement(5503..5820)
                     /locus_tag="VYO11_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001151647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV1596467.1"
                     /translation="MAKVTIMLACAAGMSTSLLVTKMQKAAEDKGLDAEIFAVPAPEA
                     EEIVATKEVNVLLLGPQVRYLLGDFQEKLKDRQIPVAVIPMTDYGMMNGSKVLDLAES
                     LLD"
     gene            complement(5835..6731)
                     /locus_tag="VYO11_001969"
     CDS             complement(5835..6731)
                     /locus_tag="VYO11_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HEV1596468.1"
                     /translation="MKRLISANPSEILQMNAEELKQSILASEGRVVLSENVVTRETFV
                     GDITNSEIARAFGADMILLNCVDVFEPKIYALDSSGDDVIHRLHQLVACPIGVNLEPI
                     DPSAKMLEETQEIVAGRVASVETLKRIEELGFDFVCLTGNPGTGVSNREIIKAVQTAK
                     ENFSGLIIAGKMHGAGVNEPVAELSVAEQLLEAGADVILVPAVGTVPAFHDQELREVV
                     DLVHSKGGLVLSAIGTSQETSDTDTIKEIALRNKICGVDIQHIGDAGYGGLATVDNIY
                     ALSKAIRGVRHTVSRLARSVNR"
     gene            complement(6734..7996)
                     /locus_tag="VYO11_001970"
     CDS             complement(6734..7996)
                     /locus_tag="VYO11_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEV1596469.1"
                     /translation="MEKLLQEKLLPVAARLGNNKALVSIRDGITLTIPLLLIGSLLMV
                     IASFPIPGWEKYLGDIGVADYLWKGVDSSFGLLGLVASFGIAYFMARQYKVDGIPAGI
                     VSLSSFITVTPFIRGEAGAGMPTAFMASKGLFVAMILGLINGYIYQWFINHNIQIKMP
                     DGVPPAVSKSFSAIIPGAVTIVGWLIVYATLDKLSLPNLHEIAQVALGGPLGLLGNNV
                     IGLLILIFLNSSFWFVGLHGGNVVNAVMKPLWLANLDANKVAYQTGETLPNIFTSVFM
                     DNFVFIGGGGATIGLVLALGYLAHKKKASKQLKTLAPITVIPGLFNINEPAMFGVPIV
                     LNILLLVPFILAPMFNLLVAWGAMASGLVPLTYTDPGWTMPPVISGLLATGSISGSLL
                     QIVLIVLDVLLYLPFVIAIEKRFKLLED"
BASE COUNT         2774 a         1594 c         1278 g         2449 t
ORIGIN      
        1 tttttgatat taaaataaaa aaggagggta ggcagtgttg tgatcaatta ttgctggagg
       61 tcttattggt ctcttggcag gtaaaatcac taaaaaagta gttctatggg aatcatcgca
      121 aatgtattcg ctggtttagt cggggcatat gcaggacaat ctcttttagg tagttggggt
      181 ccatcaatcg ctggaatggc tttgctccca tctattgtag gtgcagcgat tgtgattact
      241 gtagtgtcat tctttacagg tagaaagtaa acttttcgcc agtaaagtta gcaaactatt
      301 tttaaatcaa tgacgggaaa aatagtttaa atgttaaatc gaaaggattg tatatgtcaa
      361 aagcaaagaa aatatgtttc attattttct gtattttaat cttgacaatt ttccttcctg
      421 ttttgataga ttatcatcaa gttagtgatc taggtattca tctacttagc tggagacaga
      481 actccgtagt tgaattctat cttgctagat atgtcttttg ggggacagtg gttctatcaa
      541 ctttagtttt attatccatt ttagttgtga tgttttatcc taaacgttac ttggaaatcc
      601 aacttgaaac taaaaacgat acattaaaat taaagaattc ggcaatcgaa ggttttgtta
      661 gaagtttggt gagtgatcat agattgatca agaacccaac tgttcatgta aatttacgaa
      721 aaaataaatg tttcgttcat gtagaaggta aaattcttcc ttcagacaac atcgctgaca
      781 gatgccaaat aattcaaaat gaaataacta atggattgaa gcagtttttt ggtattgagc
      841 gtcaagtaaa acttgaagtt gcagtaaaaa attaccaacc aaaacctcaa aacaaaaaga
      901 ctgttagtcg tgtgaagtaa ggaagtaaaa aatggaatgg cttaaacaat atcgatatcc
      961 aattatcgct ggtctcatag gcgtatttct ggcttgtttg attgtctcct ttggcttctt
     1021 caaaacaata tttgtattga ttttaggagc actgggagtt gcagctggat tatatatcga
     1081 aaaaaactat atagataaat aaaaaaataa aaattactaa tttaattaaa ggagtttcat
     1141 atgtcaaacg aaaaaaacac aaacactaac gtagaaaaga aagatgctac tgttgtagct
     1201 cacgaaatca aaggggaact tacttacgaa gataaagtta tccaaaaaat cattggtctt
     1261 tcactagaaa acgtttcagg tcttttggga atcgatggtg gtttcttctc aaatcttaaa
     1321 gaaaaaatcg ttaacagcga tgacgtaaca agtggtgtta acgtagaagt tggtaaaaca
     1381 caagttgcag ttgacttaaa cgttattgtt gagtaccaaa aaaatgttcc agctttatat
     1441 tcagaaatca gagaaatcgt atcttcagaa gttgctaaaa tgactgactt ggaaattgtt
     1501 gaaatcaacg taaacgttgt cgacatcaaa actaaagaac agcatgaagc agactcagta
     1561 agccttcaag atcgcgtatc tgacgttgct gaatcaacag gagaattcac ttcagaacaa
     1621 ttcgaaaaag ctaaatctgg tcttggatct ggtttctcaa ctgttcaaga aaaagttagc
     1681 gaaggtgtag aagctgttaa aggtgcagca aatggtgtag tatctcacga aaacactcgt
     1741 gtaaactaag ataaaataaa tataacagga gaaattatca tgtcagtaga agaaaaatta
     1801 aatcaagcta aaggttctat taaagaaggt gttgggaaag ccatcggtga tgaaaaaatg
     1861 gaaaaagaag gagcagctga aaaagttgtt tctaaagtaa aagaagttgc cgaagacgct
     1921 aaagacgctg tagaaggtgc tgtagaaggt gttaaaaaca tgttgagtgg cgacgataaa
     1981 taaggttaaa agttacttta tcttttttgg taacattagt caaaagagtc tgagtcaaga
     2041 tgattctcag aaaacaaaaa gctagagatt cccaattgcg gaactctagc tttttaattt
     2101 tgcctctttc tcttattata tttcagcagg ttgttggcca tgagtatgaa tcccatgtca
     2161 attctcactt gacgcttacc tctcagatga catctcttat aacccaaaca aacctttatc
     2221 tgcccaaaga cagatttcat atcaatctta cgtttagcga aaatttgtct acccttggaa
     2281 gataaaagtg cctgatattc tttagttttt aaacactggt aacgttcatt catatacagt
     2341 cccttttgag gggctgattc aggttcataa tcgcagtcaa cattgatttc aaggctgttt
     2401 gctttctatc tccccttttt cataatgtat agtaaaatga aataataaca ggacgaatcg
     2461 atcgggacag tcaaatcgat ttctaacaat gttttagaag tagaggtgta ctattctagt
     2521 ttcaatctac tatattttcg tacaggtgct tcaatagttt ctatagtaaa atgaaccaaa
     2581 aatagtacac gttgcggtat aatgttcttg tggcatattc attagatttt cgtaaaaagt
     2641 tctctcctat ttgtgagcga acaggtatag tcaattgatt gtcagtttga agaccaagag
     2701 tcgtaaggca aaggatatgg cagaatccat ccaagggtgg ctggcacaat ttctagtgaa
     2761 cctctttaaa tctattacgt ttgactgtgg aaaagagttt tcaaaatgga aagatatttc
     2821 caatcatcac gatagtgaga gcttttttgc gaatctagga tgtccaagac agcggtgtct
     2881 caacgaacat tcaaatagac ttttaaggtg tcatgacttg ccaaagcaga cagatttcaa
     2941 cgaagtcagt caagaatttt aggctgggta aaaactcaat ttcaggagaa aatgaaataa
     3001 atattcccac aataaaacgc atagtatcaa agtttttcca acacctgata ttatacattt
     3061 tttaatttta aagacttttt cccagcctca agaaatcaca tcccacctaa atcctttgga
     3121 taccaaatac ctcatcaggt attttctgag ttggtaagac tgtctagctt aatttgacaa
     3181 atggagggcg ttaaatccag tttttacagg aagtctattt aaatattttc acactgacct
     3241 tacaaaatat gaaataaatt atataaagtc attcccatga caaagaataa catcccttta
     3301 aaacagtatc ttacccaatt ttcaggtaag acttttgata caaccgtccc caatacccct
     3361 ccgcatatag aagcaagaaa aataactgga acaggtgcta aatgatactg atttaaacct
     3421 gtaaccacaa caattgtagc caaatgagac aactgggaaa agaaaataat tgcaagagaa
     3481 tacatcgttg cttcttttat cgaaatagaa aaaaacacca tcaataaaga tacattgagc
     3541 ggaccaccac caatccctaa aaaactagaa atcaagccca atagaagacc acaaatcata
     3601 tagaatccta tcttatcaaa ttgataagtt tttttaaaat ctgttaaaac aaatgataca
     3661 agtagcatca caaatagtaa aatcatttga acaatggata ctagccgtac tgataactga
     3721 gataacaaaa cttgaaaaat aagatgacct agaaatcctc ctaaaacaga agaaaaggat
     3781 accgtaaaaa tcaatctcca ttttatctct ttactttgtg aaaatctttt gattgttgaa
     3841 ataatcgcca ttataaaaac agagaaacta gaataaaaag caatatcact gaccgaatgg
     3901 tatccaaaac tatccataag tggcttaatt ataattccac cacccatgcc tgatatagaa
     3961 cccaatccac tagctattat aatgattaga aaataaataa tctcaaccac tttttaagtc
     4021 catcctattc tttcaaacat ctaaaaccta gatggctact agtggaagta gaaatacatc
     4081 catttctagc agctactcgg tatcgattac aataagaaca atgacataaa aaggaacctc
     4141 ctctgatagc atactcctca tcttgtatcc catattttgg taactcatag tcatcttcat
     4201 taaaactagc taataaggta tatctcggat tgcgacacca ttcccaaaca ttcccaatca
     4261 tttgatatag accaaaatca ttaggtaaaa attcatagac aggagccgtt cctataaatc
     4321 catctaaggc agtattttca taaggaaatc ttccttgcca agtattggca tgataatatc
     4381 caccttctaa aagagtatct ccccaaggat attcagattg tcttcctcct ctagcagcat
     4441 attcccactg tgcttcagtc ggtaaagaca ttccgctcca attacagaaa gccaatgcat
     4501 cttctaaagc aacatgaact actggatggt cttctaaacc cactagatta ctattctcac
     4561 cgtagggatg tttccagcaa gcgttcggaa cttgtaacca ccacggagtc ccagcaggat
     4621 gaggatatcc ctccctttct gcctctggca ttaatatggt ttcctggaat cacattccca
     4681 atagttacca tcagattttt accatcaaat gctagattat caattccttg taagatttga
     4741 tctaatttca catctcctac atttgccaaa gggaaactct ttgtaactgt acttccaatc
     4801 gaaatgacaa acgaagcaag cgataccaaa ccagcagaaa ctgtatcaac cttataaatc
     4861 ttagcgatat tcacttccaa gcaatagatg aacaataagg aaacaattgg tatacttccc
     4921 ttgaatacca aattattgat gtcaacaagc cactgaaagg ttttcgtaat actttctagg
     4981 tgaaattgtt gtggtaaatc cactagaaaa gcatttaata acaaagcaat ggaacctgtc
     5041 ataataacag gcatagtccc cacaaatgaa tcacgtaaag caactaaaaa cttctgattc
     5101 ccaactttca ttgcaattgg agaaagtttt tcttgcattt tatccaacat tgtattcata
     5161 gcaaattcct aatttttttc aaatcgttcg tatacttcta ccacttcttt cgccaagtca
     5221 acaaaggtca gactcgtcat taaatgatct tgcgcgtgta ccatcaagag gctaattgat
     5281 gtttcttccc cctgtgcctc ttttgtcaac atttctgttt gagccttatg cgcctgtaat
     5341 aaggcagcat tcgcatcagc taatcttcga ttggctttag agaaatcccc tttttttgct
     5401 gcctgaatag cctccatagc attacttttg gcatccccac catacataat tagccccatt
     5461 acagattcta aattactttc atccataaca ttctcctcaa tcttagtcta ataaactttc
     5521 agctaaatct aaaactttag aaccattcat cattccgtaa tctgtcatcg gaataaccgc
     5581 cacaggaatc tgtctatctt ttagtttttc ttgaaagtcc cctagtaaat agcgaacttg
     5641 ggggcctaaa agcaacacat ttacttcttt tgttgctaca atttcttctg cttcaggagc
     5701 tggaactgca aaaatttctg catccaaccc cttatcttct gctgcctttt gcatctttgt
     5761 cactagcaga cttgtactca tacctgctgc acatgctaac ataattgtta ctttagccat
     5821 agcttactcc tttatcacct atttactgac ctagccaagc gagatactgt atgtctcact
     5881 cctctaattg ccttgctcaa tgcataaata ttatcgactg ttgccagtcc cccatatcct
     5941 gcgtcaccta tatgttgaat atcaactcca caaattttat ttctaagtgc aatttcctta
     6001 atagtatctg tatcagatgt ttcttggcta gtaccaatag cactcaatac aagaccaccc
     6061 ttactatgaa cgagatcaac gacttcacgc aactcttggt catgaaaggc tggaacggtt
     6121 ccaactgctg gaacaagtat cacatccgca cctgcttcca acaattgctc tgcgacagaa
     6181 agctctgcca caggctcatt cactcctgcc ccgtgcatct tacctgcaat aatcaaacca
     6241 gaaaagtttt ccttagcagt ttgaacagcc ttaatgattt ctcgattgct aactcctgtt
     6301 ccaggatttc cagtcaaaca gacaaagtca aaacctaact cctctattcg cttcaatgtt
     6361 tcaacactag caacacgacc tgcaacaatt tcctgtgttt cctctagcat ctttgcagat
     6421 gggtcaatcg gttccaaatt tacaccaatt ggacaagcaa caagctggtg taagcgatga
     6481 ataacatcat cacctgaact atccaaagca taaattttag gctcaaaaac atcaacacaa
     6541 ttcaataaaa tcatatcagc tccaaaagct ctagcaattt cagaattagt tatatcccca
     6601 acaaatgtct cacgagtaac tacattttca gatagaacaa ctctaccttc acttgctaaa
     6661 atactttgtt ttaattcttc agcattcatc tgtaatatct cagatggatt tgcactaatt
     6721 aaacgtttca ttctcaatcc tccaataact taaaccgttt ttcaatagct attacaaatg
     6781 gtaaataaag taagacatcc aaaacaatca atacaatttg taataatgaa ccagaaatac
     6841 ttcctgtagc aagtaaacca cttataacag gtggcatagt ccaacctgga tctgtataag
     6901 ttagcggaac caaacctgat gccattgctc cccacgctac tagtaagtta aacattggag
     6961 ctaagataaa tggaactagt aacaaaatgt tcaaaacaat aggaacgcca aacattgctg
     7021 gttcatttat attaaataat ccaggtataa cagttatagg tgccaaagtt tttagttgtt
     7081 tactagcttt cttcttatgt gctaaatatc ctaacgcaag aactaaacct atggttgcac
     7141 caccgccacc tatgaataca aaattatcca taaatacgct agtaaaaata tttggaagag
     7201 tttctccagt ttgataagct actttatttg catctagatt agctaaccat aacggtttca
     7261 taactgcatt aacaacattt cctccgtgta atcctacaaa ccaaaaacta ctattaagga
     7321 aaattaagat aagaaggcca ataacattat ttcctaaaag tccaagtgga cctcccaaag
     7381 ctacttgagc aatttcatga agattaggta aacttaattt atctaaagtt gcataaacaa
     7441 tcaaccaacc aacaatagtc actgcaccag gaataatggc actaaagctt ttagatactg
     7501 ctggtggaac accatccggc atttttatct gtatattatg atttataaac cattggtaga
     7561 tatagccatt aatcaatcct aaaatcatag caacaaataa accttttgat gccatgaaag
     7621 cggtaggcat tcctgctcca gcctctcctc taatgaaagg cgtaactgta ataaaagatg
     7681 ataatgacac aataccagca ggaataccat caactttgta ttgtctagcc ataaagtaag
     7741 cgataccaaa actagctaca agaccaagta atccaaaact actatcaaca cccttccata
     7801 aatagtcagc aacaccaata tcacccagat atttttccca tcctggaata ggaaaacttg
     7861 caataaccat tagtaatgaa cctatcaaca ataaaggtat agttagagta ataccgtctc
     7921 gaatagaaac caacgcttta ttattaccca atctagctgc tactggaagt aacttttctt
     7981 gtaataattt ttccataacc ttttcctctt aaatatattt tattatcaaa agttatcaat
     8041 tatctttatt ttttgacgtc aagttgttat ttgattatct tttgttattt atatt
//
LOCUS       DAVLXH010000075         7833 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00028199
            SAMN33607166-rid17955573.denovo.076, whole genome shotgun sequence.
ACCESSION   DAVLXH010000075 DAVLXH010000000
VERSION     DAVLXH010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607166
            Sequence Read Archive: SRR23725544
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7833)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7833)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721421.1
            Genome Coverage       :: 115x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:42:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,210
            CDSs (total)                      :: 2,161
            Genes (coding)                    :: 2,023
            CDSs (with protein)               :: 2,023
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 73 of 138
            Pseudo Genes (incomplete)         :: 60 of 138
            Pseudo Genes (internal stop)      :: 40 of 138
            Pseudo Genes (multiple problems)  :: 31 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7833
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607166-rid17955573.denovo.076"
                     /strain="AUSMDU00028199"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1349"
     misc_binding    173..398
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            470..1831
                     /gene="trpE"
                     /locus_tag="VYO11_001971"
     CDS             470..1831
                     /gene="trpE"
                     /locus_tag="VYO11_001971"
                     /EC_number="4.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate synthase component I"
                     /protein_id="HEV1596470.1"
                     /translation="MERIIHGDVLSPILAYMRLKGQHKVILESIPRDKETARFSILAY
                     NPVFEIKFENGILYQNGQVIDRDPLDFLYEVTHKRQHHSDLPFGGGAIGFVGYDMISL
                     YEEIGQIPEDTIGTPDMHFFVYESYMVFDHKKEKIHVIEDALYSERSQEELEKALNQV
                     LEELRIPAPNEFEYLDLSPLDFKPHIAPQKFEEMVETARDLIRNGDMFQCVLSQRFSA
                     EVTGNPFDFYRNLRVTNPSNYLYFYDFGDYQIIGASPESLVSVKNGIVTTNPIAGTRP
                     RGATDEEDKDLATDLLSDEKETAEHRMLVDLGRNDIGRISETASVQVTKYMEVELFRY
                     VMHLTSVVKGRLLPELTAMDALKATLPAGTVSGAPKIRAMRRIYELETEKRGVYAGAI
                     GYLSATGDMDLAIAIRTMILKNQRAYVQAGAGIVYDSIAQNEYQETINKAKSMTRIGE
                     LRP"
     gene            1828..2394
                     /locus_tag="VYO11_001972"
     CDS             1828..2394
                     /locus_tag="VYO11_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate/anthranilate synthase
                     component II"
                     /protein_id="HEV1596471.1"
                     /translation="MILLIDNYDSFTYNLAQYIGNFAEVQVLRNDDSKLYEEAEKADG
                     LVFSPGPGWPVDAGKMEDMIRDFAGKKPILGICLGHQAIAEVFGGKLGLAPKVMHGKQ
                     SNINFEAPSVLYQGIEDGRAVMRYHSILIEEMPEDFEVTARSTDDQAIMGIQHKNLPI
                     YGFQYHPESIGTPDGLSSIRNFIEKVVK"
     gene            2405..3409
                     /gene="trpD"
                     /locus_tag="VYO11_001973"
     CDS             2405..3409
                     /gene="trpD"
                     /locus_tag="VYO11_001973"
                     /EC_number="2.4.2.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate phosphoribosyltransferase"
                     /protein_id="HEV1596472.1"
                     /translation="MKEIIEKLAKFENLSGVEMMDVIERIVTGRVTEAQIASLLLALK
                     MKGETPEERTAIAQVMRGHAQHIPTEIHDAMDNCGTGGDKSFSFNISTTAAFVLAGGG
                     IHMAKHGNRSISSKSGSADVLEALGINLDLKPAELGKVFDKTGIVFLFAKNMHPAMKY
                     IMPARLELGIPTIMNLTGPLIHPMALETQLLGISRPELLESTAQVLKNMGRKRAIVVA
                     GPEGLDEAGLNGTTKIALLENGEISLSSFTPEDLGMEGYAMEDIRGGNAQENAEILLS
                     VLKNEASPFLETTVLNAGLGFYANGKIDSIKEGVALARQVIARGKALEKLRLLQEYQK
                     "
     gene            3406..4173
                     /gene="trpC"
                     /locus_tag="VYO11_001974"
     CDS             3406..4173
                     /gene="trpC"
                     /locus_tag="VYO11_001974"
                     /EC_number="4.1.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011227478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="indole-3-glycerol phosphate synthase TrpC"
                     /protein_id="HEV1596473.1"
                     /translation="MSQEFLARILEQKAREVEQMKLEQIQPLRQTYRLAEFLKNHQDR
                     LQVIAEVKKASPSLGDINLDVDIVQQAQTYEENGAVMISVLTDEVFFKGHLDYLREIS
                     SQVEIPTLNKDFIIDEKQIIRARNAGATVILLIVAALSEERLKELYDYATELGLEVLV
                     ETHNLAELEVAHRLGAEIIGVNNRNLTTFEVDLQTSVDLAPYFEEGRYYISESAIFTG
                     QDAERLAPYFNGILVGTALMQAENVAQRIKELQIDKG"
     gene            4160..4759
                     /locus_tag="VYO11_001975"
     CDS             4160..4759
                     /locus_tag="VYO11_001975"
                     /EC_number="5.3.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylanthranilate isomerase"
                     /protein_id="HEV1596474.1"
                     /translation="MTKVKICGLSTKEAVETAVSAGADYIGFVFAPSKRQVTLEEAAE
                     LAKLIPADVKKVGVFVSPSRVELLEAIDKVGLDLVQVHGQVADDLFENLPCASIQAVQ
                     VDGNGHVPNSQADYLLFDAPVAGSGQTFDWGQLDTTGLAQPFFIAGGLNEDNVVKAIQ
                     HFTPHAVDVSSGVETDGQKDHEKIRRFIERVKHGISGTK"
     gene            4737..5960
                     /gene="trpB"
                     /locus_tag="VYO11_001976"
     CDS             4737..5960
                     /gene="trpB"
                     /locus_tag="VYO11_001976"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit beta"
                     /protein_id="HEV1596475.1"
                     /translation="MAYQEPNKDGFYGKFGGRFVPETLMTAVLELEKAYRESQADPSF
                     QEELNQLLRQYVGRETPLYYAKNLTQHIGGAKIYLKREDLNHTGAHKINNALGQVWLA
                     KRMGKKKIIAETGAGQHGVATATAAALFNMECTIYMGEEDVKRQALNVFRMELLGAKV
                     EAVTDGSRVLKDAVNAALRSWVANIDDTHYILGSALGPHPFPEIVRDFQSVIGREAKQ
                     QYRDLTGQNLPDALVACVGGGSNAIGLFHPFVEDESVAMYGAEAAGLGVDTEHHAATL
                     TKGRPGVLHGSLMDVLQDAHGQILEAFSISAGLDYPGIGPEHSHYHDIKRASYVPVTD
                     EEALEGFQLLSRVEGIIPALESSHAIAFAVKLAKELGPEKSMIVCLSGRGDKDVVQVK
                     DRLEADAAKKGEAHA"
     gene            5953..6729
                     /locus_tag="VYO11_001977"
     CDS             5953..6729
                     /locus_tag="VYO11_001977"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit alpha"
                     /protein_id="HEV1596476.1"
                     /translation="MPKTLTKKLNAIKAAGKGIFVPYIMAGDHEKGLDGLAETIHFLE
                     DLGVSAIEVGIPFSDPVADGPVIEEAGLRSLAHGTSTQALVETLKIIKTEIPLVIMTY
                     FNPLFQYGVENFVKDLADTAVKGLIIPDLPHEHANFVEPFLADTDIALIPLVSLTTGI
                     ERQKELIEGAEGFVYAVAINGVTGKSGNYRADLDKHLAQLHQVADIPVLTGFGVSSQA
                     DLERFNAVSDGVIVGSKIVKALHQGEPIQDFIRQAVAYQK"
     gene            complement(6701..7360)
                     /locus_tag="VYO11_001978"
     CDS             complement(6701..7360)
                     /locus_tag="VYO11_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000564993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HEV1596477.1"
                     /translation="MIDFYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTRLR
                     PLDLIPILSQVFNRFRCRYCKVRYPVWYALFELSLGLLFLLYSWGWLSLGQVVLITAG
                     LTLGIYDFHHQEYPLLVWMTFQLILIASSGWNLVMVSFLILGILAHFIDIRMGAGDFL
                     FLASCALVFSVTELLILIQFASATGILAFLLQKKKERLPFVPFLLLATCLIIFGKLLL
                     V"
     gene            7430..>7833
                     /locus_tag="VYO11_001979"
     CDS             7430..>7833
                     /locus_tag="VYO11_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000155432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1596478.1"
                     /translation="MTIRFEEKVSTENAQFVCQWSNSLGKSFQEQWMGPRIPFLLTLQ
                     ALEGVFSIFDEQEFVGFIQKIRLEDSNLHIGRFFINPQKQEQGLGSKALRKFVSLAFE
                     NEDIDSISLNVFEANQRAQNLYQKEGFEIVQMV"
BASE COUNT         2336 a         1562 c         1939 g         1996 t
ORIGIN      
        1 agatagaact gacgaagtca gtaaccatac ctacggcaag gcgacgttga cgcggtttga
       61 agagattttc gaagagtata aaggtgtatc gaaataaaaa tctcctcatc aatatctctg
      121 gtcgtggagg caaggaccta gctgcgattg cagactacct tgaagctaaa aaataaaaga
      181 tggaaaaatt acagtccttt ctctcacaga gagcttgtgg ttgctggaaa caagcagaga
      241 aagctgtaag gttgggtcca tctgaaacga gagaagaaaa catcattctc aagggagtgc
      301 cctttatcgc acagcctgtt acagaatctt tctaagacag gaatgagaga taggagaaat
      361 cctataattg aggtggcacc gcgaatttcg tcctcacgca agttattttg cgtggggatt
      421 tttcatacag tcgccacgga ctagaagtag aactgaaagg gaaattacaa tggaacgaat
      481 cattcatgga gatgtcttat caccaatctt ggcttatatg cgcctaaagg ggcaacacaa
      541 ggttatctta gagagtattc cgagagacaa ggaaacagct cgtttttcta tcctagccta
      601 taatccagtt tttgagatta agtttgaaaa tggaattctt tatcaaaatg gtcaagtgat
      661 tgatcgggat cccttggatt tcctttatga agtgactcat aagagacagc accattcaga
      721 cctccctttt ggtggtgggg caattggttt tgttggttac gatatgattt cgctttatga
      781 agaaattggt caaattcctg aagatacaat tggaacgcca gacatgcatt tcttcgtcta
      841 tgagagttac atggtctttg accacaagaa ggagaaaatc catgtcatcg aggatgctct
      901 ttatagcgag cgtagtcaag aagaattgga aaaagccttg aaccaagtgc ttgaagaatt
      961 acgcattcct gctccaaatg aatttgaata cttggatcta tctccgttag acttcaaacc
     1021 tcatatcgct cctcagaagt ttgaggaaat ggtggaaaca gctcgtgact tgattcgtaa
     1081 tggtgatatg ttccaatgtg tactcagtca gcgcttctca gcagaagtta ctggaaatcc
     1141 atttgacttc tatagaaatc tccgcgtgac taatccttct aattacctct atttctatga
     1201 ttttggggat tatcaaatca tcggtgctag cccagaaagt ttggtttctg tcaaaaatgg
     1261 catcgtgaca accaatccga ttgccggtac gcgaccaaga ggtgctacgg atgaagaaga
     1321 caaggatttg gcgacagacc tgctttcgga tgagaaggaa acagcagagc atcggatgtt
     1381 agtagacttg gggcgtaatg atattggtcg catctctgaa acggccagtg tccaagtcac
     1441 caagtatatg gaagtggagc tcttccgcta tgttatgcat ttgaccagcg tggtcaaggg
     1501 acgtttgctt ccagaactca ctgctatgga tgccttgaaa gcaacacttc cagctggaac
     1561 cgtttctgga gcaccaaaga ttcgagcgat gagacgcatc tatgaactgg aaacagaaaa
     1621 acgtggcgta tacgcaggag caatcggcta cttgtctgcg acgggtgata tggatttggc
     1681 cattgccatc cgaaccatga ttctcaaaaa tcaaagagcc tatgtgcagg ctggggcagg
     1741 gattgtctac gactctatcg cccaaaacga ataccaagaa accattaaca aagcaaaatc
     1801 tatgactaga attggagaac taagaccatg attttattga ttgacaacta tgattctttt
     1861 acctataact tggcccaata cattgggaat tttgcagaag ttcaggttct gagaaatgat
     1921 gattccaagc tgtatgaaga agctgaaaaa gcagatggtc tggtcttttc tcctggtcct
     1981 ggttggccag ttgatgctgg aaagatggaa gacatgattc gtgattttgc aggcaagaag
     2041 ccgattctag ggatttgttt gggccaccaa gccattgcag aagtctttgg tggtaagcta
     2101 ggtttggctc caaaagtcat gcatgggaaa cagagcaata tcaactttga agcgccatct
     2161 gttttgtatc aaggtattga ggatggccgt gcggtcatgc gttatcacag tattttgatt
     2221 gaggaaatgc cagaagactt tgaagtgaca gctcgttcga ctgatgacca agccatcatg
     2281 gggattcaac ataaaaacct accgatttat ggcttccagt accatccaga gagcattgga
     2341 acgccagacg gcttgtcttc tattcggaat tttatcgaga aggttgtaaa gtgaggaaac
     2401 taggatgaaa gagattattg aaaaactagc aaaatttgaa aatttatcag gtgtggaaat
     2461 gatggatgtc attgagcgta tcgtaactgg gcgtgtaact gaagcgcaga ttgcttctct
     2521 cctcttagct cttaagatga agggggaaac acctgaagaa cgcacagcca ttgcccaagt
     2581 catgagagga catgcccagc atattccaac tgagattcat gatgccatgg acaactgtgg
     2641 tacaggtggg gacaagtctt tcagttttaa tatttccaca actgcagcct ttgtcttggc
     2701 tggtggcggt attcacatgg ccaagcatgg taaccgctcg atttcttcta aatctggttc
     2761 cgcagatgtc ctcgaagcct tgggaatcaa tcttgacctc aaaccagctg aactaggtaa
     2821 ggtctttgat aaaactggaa ttgtctttct cttcgctaaa aatatgcacc cagctatgaa
     2881 atacatcatg ccagctcgtt tggaattggg aattccaacg attatgaact tgactggtcc
     2941 actgattcat ccaatggctt tagaaacaca gcttcttgga attagtcgtc cagaactcct
     3001 agaaagtaca gctcaggttt tgaaaaatat gggtcgcaaa cgtgccatcg tggttgctgg
     3061 accagaaggg ttggatgaag ctggcttgaa cggaacaacc aagattgcac ttcttgaaaa
     3121 tggcgaaatc agcttgtcaa gctttactcc agaggatttg ggaatggaag gctatgctat
     3181 ggaagatatt cgtggtggga atgctcagga aaatgcagaa attttgctta gcgttctgaa
     3241 aaacgaagca agtccattct tggaaacgac agtcttgaat gctggtcttg gtttctatgc
     3301 taatggtaag attgatagca tcaaggaagg agttgccttg gcccgtcaag tgattgctag
     3361 aggcaaggcc cttgaaaaac tcagactgtt acaggagtac caaaaatgag tcaggaattt
     3421 ttagcacgaa tcttagagca gaaggcgcgt gaggtggagc agatgaagct ggagcaaatc
     3481 cagcctctgc gccagaccta tcgcttggca gaatttttga agaatcatca ggaccgcttg
     3541 caggtaatcg ctgaggtcaa gaaagctagc cctagtttgg gagatatcaa tctcgatgtg
     3601 gatattgtgc aacaggccca gacttatgaa gaaaacggag cagtgatgat ttcggtgttg
     3661 acagatgagg ttttctttaa agggcatttg gattatctac gggaaatttc cagtcaggta
     3721 gagattccga cgctcaacaa agactttatc atagatgaaa agcaaatcat ccgcgctcgc
     3781 aatgcaggtg cgacagttat cttgctcatt gtggcagcct tgtccgaaga acgcctcaag
     3841 gaactgtatg actacgcgac agagcttggt ctggaagtct tagtggagac tcacaatcta
     3901 gctgaactag aggtagccca cagacttggt gctgagatta tcggggtcaa caaccgcaac
     3961 ttgactacct ttgaggtcga cttgcagacc agtgtagatt tagcccctta ctttgaggaa
     4021 ggtcgctatt acatttctga atctgccatt ttcacagggc aggatgcgga acgactagcc
     4081 ccatacttta acggaatttt ggtagggaca gctcttatgc aggcagaaaa tgtggcccag
     4141 agaatcaagg agttgcagat tgacaaaggt taaaatttgt ggactatcga ccaaagaagc
     4201 ggtggaaaca gccgtttcag caggagccga ctatatcggt tttgtctttg cacctagtaa
     4261 aagacaggtg actttagaag aggcagctga gttggcaaag cttattcctg cagatgtgaa
     4321 aaaggttgga gtatttgttt caccaagtcg ggtagaactg ctggaagcga ttgacaaagt
     4381 tggcttggac ttggttcaag ttcacggtca ggtggcagat gatttatttg agaatttgcc
     4441 ttgtgccagt attcaggctg tgcaggtaga tggaaatggg catgtcccca attctcaggc
     4501 agactatcta ctctttgatg ccccagtggc agggagtggc cagacctttg actggggtca
     4561 actggatacg actggactag cacagccctt ctttatcgca ggtggcctta atgaagataa
     4621 tgtagtaaaa gcaattcaac attttactcc ccatgcagta gatgtatcga gcggagtgga
     4681 gacagatgga caaaaagatc atgaaaagat tagaagattt atagagaggg taaagcatgg
     4741 catatcagga accaaataaa gatggatttt acggaaaatt cggcggacgt tttgtcccag
     4801 aaacattgat gacagcagtt ttggagttgg agaaggccta ccgtgaaagt caggcagacc
     4861 caagtttcca agaggaatta aaccaacttt tgcgccagta cgtaggacgt gaaactcctc
     4921 tttattacgc aaaaaacttg acccagcata tcggcggagc caagatttat ctcaaacggg
     4981 aagaccttaa ccatacagga gcccacaaga ttaacaatgc cttaggacaa gtttggcttg
     5041 ccaaacgcat gggtaaaaag aaaattatcg cagaaacagg tgctggtcag cacggtgtgg
     5101 caactgcaac tgctgcggcc ctctttaaca tggaatgtac catctacatg ggtgaggaag
     5161 atgtcaaacg ccaagccctc aatgtcttcc gaatggagct tttgggagct aaggtcgagg
     5221 ccgtgacaga tggttcgcgc gtgctcaagg atgcggtcaa tgcagccctt cgttcatggg
     5281 tggctaatat cgatgatacc cactatattc ttggttctgc cttggggcct catccatttc
     5341 cagaaattgt tcgtgacttc caaagtgtca ttggtcgaga ggctaaacaa cagtaccgtg
     5401 acttgacagg acaaaatctg ccagatgccc tagtagcctg tgttggtggt gggtcgaatg
     5461 ccatcggtct cttccatccc tttgtagaag atgagtcagt agccatgtat ggagctgaag
     5521 cggctggact tggtgtggat acggagcacc acgcagctac cttgaccaag ggtcgtccag
     5581 gtgtccttca cggttccctc atggatgtgc tccaagatgc ccatggtcaa attcttgaag
     5641 ccttctctat ctcagcaggt ttggactatc ctggtatcgg tccagagcat tctcactacc
     5701 acgatattaa acgtgccagc tatgtccctg tgacagacga agaagccttg gaaggattcc
     5761 aactcttgtc tcgtgtggaa gggattatcc cagctttgga atctagccat gctatcgcct
     5821 ttgcggtgaa attggccaaa gaacttggac cagaaaagtc tatgattgtc tgcctatcag
     5881 gtcgtgggga caaggatgtg gttcaagtca aagaccgctt ggaagcagat gcagcaaaga
     5941 agggagaagc tcatgcctaa gacactaaca aaaaaattaa atgctattaa agcagctgga
     6001 aaaggaattt ttgttcccta tatcatggct ggtgaccacg aaaaaggttt ggacggtctt
     6061 gctgaaacaa ttcacttttt agaagatttg ggtgtctctg caattgaagt gggtattccc
     6121 ttttcagacc ctgttgcaga tggacctgtt atcgaagaag ctggcttgcg cagtttagcc
     6181 cacgggacct ctacccaggc tttagttgaa accttgaaaa tcattaaaac agagattcca
     6241 ctggtcatca tgacctactt caaccccctc tttcagtacg gtgtggagaa ctttgtcaaa
     6301 gatctggctg atacagctgt gaagggcttg attatcccag acttgcctca tgaacatgcc
     6361 aactttgtag aaccattttt ggcagataca gatatcgcct tgattccttt agtaagcttg
     6421 accacaggaa ttgagcgcca gaaagagttg attgaagggg cggagggatt cgtctatgcc
     6481 gttgccatca atggggtaac agggaaatca ggcaattacc gtgcagattt ggacaagcac
     6541 ttggcgcaac ttcatcaagt ggccgacatc ccagtcttga caggttttgg tgtatctagt
     6601 caagccgatc tggaacgctt caatgcggtg tcagatggtg ttatcgtcgg ttcaaaaata
     6661 gtaaaagctc tccaccaagg agagccgatt caggatttta tcagacaagc agtagcttac
     6721 caaaaataat caaacaagta gcaagtaaga ggaaaggcac gaaaggaagt ctttcctttt
     6781 tcttttgcag gagaaaggcc aggatacccg tcgcagaagc gaactgaatc aagatcagta
     6841 actccgttac gctaaagacg agagcacaag aagctaaaaa gaggaaatcc cctgcaccca
     6901 tgcggatatc gataaaatga gccaaaattc caagtatgag gaaggagacc atgaccagat
     6961 tccagccaga ggaagctatt aggattagct ggaaagtcat ccagaccagt aagggatatt
     7021 cctgatggtg aaagtcgtag atacccaagg tcaaaccagc ggtgattagg acgacttgcc
     7081 ccaaggagag ccatccccaa gagtaaagca gaaagaggag tcctaagctt aattcaaaga
     7141 gggcatacca gacaggatag cgaactttgc agtagcgaca gcgaaagcga ttgaagacct
     7201 gtgagagaat cggaatcaaa tctaagggac gcaagcgagt ctgacaggaa tcgcagtgac
     7261 tggctgaact gataatggat tgctctggaa aacggtcaat gaccaaacca agaaaggaag
     7321 cgagaatgct cccgacgaga aaaaaataaa aatcaatcat acttatctat tcgtaaaaaa
     7381 tgggagaaat agtataatgg agaaacatag ataaggtggt gaggaaaaga tgacaattcg
     7441 ttttgaagaa aaggtgagca cagaaaacgc tcaatttgta tgccagtggt ccaactccct
     7501 aggcaaatcc tttcaagaac aatggatggg accaaggatt ccttttctac tgacacttca
     7561 agccttggaa ggagtctttt caatctttga tgaacaagag tttgtgggat ttatccagaa
     7621 aatcaggcta gaagacagca atcttcatat cgggagattt tttatcaacc cccagaaaca
     7681 ggagcaaggc ttaggtagca aggctttaag gaaatttgtt agtttggcct ttgaaaatga
     7741 agatatagat agtatttctc taaatgtctt cgaggcaaat caaagagctc agaatcttta
     7801 ccaaaaagaa ggatttgaaa tcgttcaaat ggt
//
LOCUS       DAVLXH010000076         7721 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00028199
            SAMN33607166-rid17955573.denovo.077, whole genome shotgun sequence.
ACCESSION   DAVLXH010000076 DAVLXH010000000
VERSION     DAVLXH010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607166
            Sequence Read Archive: SRR23725544
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7721)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7721)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721421.1
            Genome Coverage       :: 115x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:42:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,210
            CDSs (total)                      :: 2,161
            Genes (coding)                    :: 2,023
            CDSs (with protein)               :: 2,023
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 73 of 138
            Pseudo Genes (incomplete)         :: 60 of 138
            Pseudo Genes (internal stop)      :: 40 of 138
            Pseudo Genes (multiple problems)  :: 31 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7721
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607166-rid17955573.denovo.077"
                     /strain="AUSMDU00028199"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1349"
     gene            26..568
                     /locus_tag="VYO11_001980"
     CDS             26..568
                     /locus_tag="VYO11_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator
                     C-terminal domain-containing protein"
                     /protein_id="HEV1596479.1"
                     /translation="MQESNKRLKTKRTIENAMVQLLMEQPFDKISTVKLVEKAGISRS
                     SFYTHYKDKYDMIEHYQSKLFHTFEYIFQKHAHHKRDAILEVFEYLESEPLLAALLSE
                     NGTKEIQNFLRNKLHIMLSTDLQKRFMQLNLNTTELEYSSIYLTHALFGVCQTWIAHG
                     KKESSQEITDFLMKMLGDTN"
     gene            complement(609..682)
                     /locus_tag="VYO11_001981"
     tRNA            complement(609..682)
                     /locus_tag="VYO11_001981"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(646..648),aa:Asn,seq:gtt)
     gene            complement(688..759)
                     /locus_tag="VYO11_001982"
     tRNA            complement(688..759)
                     /locus_tag="VYO11_001982"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(724..726),aa:Glu,seq:ttc)
     gene            complement(811..1563)
                     /locus_tag="VYO11_001983"
     CDS             complement(811..1563)
                     /locus_tag="VYO11_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000866085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1596480.1"
                     /translation="MKVLILEDVIEHQVRLERILDEISKESNIPISYKTTGKVREFEE
                     YIENDEVNQLYFLDIDIHGIEKKGFEVAQLIRHYNPYAIIVFITSRSEFATLTYKYQV
                     SALDFVDKDINDEMFKKRIEQNIFYTKSMLLENEDVVDYFDYNYKGNDLKIPYHDILY
                     IETTGVSHKLRIIGKNFAKEFYGTMTDIQEKDKHTQRFYSPHKSFLVNIGNIREIDRK
                     NLEIVFYEDHRCPISRLKIRKLKDILEKKSQK"
     gene            complement(1560..2885)
                     /locus_tag="VYO11_001984"
     CDS             complement(1560..2885)
                     /locus_tag="VYO11_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000362880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV1596481.1"
                     /translation="MDLFGFGTVIVHFLIISHSYHFICKGQINRKELFVFGAYTLLTE
                     IVFDFPLYILYLDGLGIERFLFPLGLYSYFRWMKQYERDRGLFLSLLLSLLYESTHNF
                     LSVTFSSITGDNFVLQYHFPFFFVVTVLTYFVTLKIIYYFHLELAYFDEDYLYPFLKK
                     VFFALLLLHIVSFVSDMVSTIKHLNSFGSILSSIVFISLLLTFFAMNSHKVQMEKEIA
                     LKQKKFEQKHLQNYTDEIVGLYNEIRGFRHDYAGMLVSMQMAIDSGNLQEIDRIYNEV
                     LVKANHKLRSDKYTYFDLNNIEDSALRSLVAQSIVYARNNGVEFTLEVKDTITKLPIE
                     LLDLVRIMSVLLNNAVEGSADSYKKQMEVAVIKMETETVIVIQNSCKMTMTPSGDLFA
                     LGFSTKGRNRGVGLNNVKELLDKYNNIILETEMEGSTFRQIIRFKREFE"
     gene            complement(2906..3031)
                     /gene="comC"
                     /locus_tag="VYO11_001985"
     CDS             complement(2906..3031)
                     /gene="comC"
                     /locus_tag="VYO11_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence-stimulating peptide ComC"
                     /protein_id="HEV1596482.1"
                     /translation="MKNTVKLEQFVALKEKDLQKIKGGEMRLSKFFRDFILQRKK"
     gene            complement(3196..3269)
                     /locus_tag="VYO11_001986"
     tRNA            complement(3196..3269)
                     /locus_tag="VYO11_001986"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(3233..3235),aa:Arg,seq:tct)
     gene            complement(3313..3792)
                     /gene="rlmH"
                     /locus_tag="VYO11_001987"
     CDS             complement(3313..3792)
                     /gene="rlmH"
                     /locus_tag="VYO11_001987"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000695929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HEV1596483.1"
                     /translation="MKIKVVTVGKLKEKYLKDGIAEYSKRISRFAKFEMIELSDEKTP
                     DKASESENQKILEIEGQRILSKIADRDFVIVLAIEGKTFFSEEFSKQLEETSIKGFST
                     LTFIIGGSLGLSSSVKNRANLSVSFGRLTLPHQLMRLVLVEQIYRAFTIQQGFPYHK"
     gene            3975..5156
                     /locus_tag="VYO11_001988"
     CDS             3975..5156
                     /locus_tag="VYO11_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine protease"
                     /protein_id="HEV1596484.1"
                     /translation="MKHLKTFYKKWFQLLVVIVISFFSGALGSFSITQLTQKSSVNNS
                     NNNSTITQTAYKNENSTTQAVNKVKDAVVSVITYSANRQNSVFGNDDTDTDSQRISSE
                     GSGVIYKKNDKEAYIVTNNHVINGASKVDIRLSDGTKVPGEIVGADTFSDIAVVKISS
                     EKVTTVAEFGDSSKLTVGETAIAIGSPLGSEYANTVTQGIVSSLNRNVSLRSEDGQAI
                     STKAIQTDTAINPGNSGGPLINIQGQVIGITSSKIATNGGTSVEGLGFAIPANDAINI
                     IEQLEKNGKVTRPALGIQMVNLSNVSTSDIRRLNIPSNVTSGVVVRSVQSNMPANGHL
                     EKYDVITKVDDKEIASSTDLQSALYNHSIGDTIKITYYRNGKEETTSIKLNKSSGDLE
                     S"
     gene            5214..5972
                     /locus_tag="VYO11_001989"
     CDS             5214..5972
                     /locus_tag="VYO11_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000410347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HEV1596485.1"
                     /translation="MEKFEMISITDIQKNPYQPRKEFDREKLDELAQSIKENGVIQPI
                     IVRQSPVIGYEILAGERRYRASLLAGLRSIPAVVKQISDQEMMVQSIIENLQRENLNP
                     IEEARAYESLVEKGFTHAEIADKMGKSRPYISNSIRLLSLPEQILSEVENGKLSQAHA
                     RSLVGLNKEQQDYFFQRIIEEDISVRKLETLLTEKKQKKQQKTNHFIQNEEKQLRKLL
                     GLDVEIKLSKKDSGKIIISFSNQEEYSRIINSLK"
     gene            6185..7546
                     /gene="dnaA"
                     /locus_tag="VYO11_001990"
     CDS             6185..7546
                     /gene="dnaA"
                     /locus_tag="VYO11_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HEV1596486.1"
                     /translation="MKEKQFWNRILEFAQERLTRSMYDFYAIQAELIKVEENVATIFL
                     PRSEMEMVWEKQLKDIIVVAGFEIYDAEITPHYIFTKPQDTTSSQVEEATNLTLYDYS
                     PKLVSIPYSDTGLKEKYTFDNFIQGDGNVWAVSAALAVSEDLALTYNPLFIYGGPGLG
                     KTHLLNAIGNEILKNIPNARVKYIPAESFINDFLDHLRLGEMEKFKKTYRSLDLLLID
                     DIQSLSGKKVATQEEFFNTFNALHDKQKQIVLTSDRSPKHLEGLEERLVTRFSWGLTQ
                     TITPPDFETRIAILQSKTEHLGYNFQSDTLEYLAGQFDSNVRDLEGAINDITLIARVK
                     KIKDITIDIAAEAIRARKQDVSQMLVIPIDKIQTEVGNFYGVSIKEMKGSRRLQNIVL
                     ARQVAMYLSRELTDNSLPKIGKEFGGKDHTTVIHAHAKIKSLIDQDDNLRLEIESIKK
                     KIK"
BASE COUNT         2685 a         1392 c         1215 g         2429 t
ORIGIN      
        1 tctaatttgt ttacaaggag gaaatatgca agaaagtaac aaacgcttaa aaacaaagcg
       61 aactattgaa aatgctatgg tacaattact gatggaacag ccatttgata aaatttctac
      121 tgtcaaatta gtagaaaaag ccggaattag tcgttccagc ttctatactc actataagga
      181 taagtatgat atgattgagc actatcaaag caagctattc catacatttg aatatatttt
      241 tcaaaaacat gctcatcaca aaagagacgc tattttagaa gtttttgaat atctagagtc
      301 agaaccactt ctggctgccc ttctttctga aaatgggact aaagaaatcc aaaatttctt
      361 acgaaataaa cttcatatca tgcttagtac agatttacaa aagcgattta tgcaactgaa
      421 tctaaatacc accgaattag aatatagtag catctatcta actcatgcac tttttggtgt
      481 ctgccaaact tggattgcac atggaaaaaa agaaagttct caagaaataa cagacttcct
      541 tatgaaaatg cttggtgata caaattgata caaaaagagg aacacagctg tgttcccttt
      601 tatctatact ccgccagtag gactcgaacc tacgacatca tgattaacag tcatgcgcta
      661 ctaccaactg agctatggcg gataaaatag tccgtacggg attcgaaccc gtgttaccgc
      721 cgtgaaaagg cggtgtctta accccttgac caacggacct tctatctgta gcagatataa
      781 ccattatatc aatttcttgc taattgtcaa tcacttttga gattttttct ctaaaatatc
      841 ttttaatttt ctaattttta atcttgaaat aggacaacga tggtcttcat agaaaacaat
      901 ttctaagttt tttcgatcaa tttctctgat attgcctata tttaccaaaa atgacttgtg
      961 aggagaataa aatcgctgag tatgtttgtc cttttcctga atatctgtca tggtaccata
     1021 aaactctttt gcaaaattct taccaataat gcgcaattta tgagataccc ctgttgtttc
     1081 aatatacaaa atatcatggt aaggaatttt taaatcattt cccttgtaat tgtagtcgaa
     1141 ataatctaca acatcttcat tttcaagtaa catactcttc gtgtagaaga tattttgctc
     1201 aattctcttc ttaaacatct catcattgat atccttatca acaaaatcta gggctgatac
     1261 ctgatattta taggttagag tcgcaaactc tgatcgacta gtgataaaga cgataatagc
     1321 gtaaggattg taatgacgaa tgagctgagc cacttcaaat ccctttttct caattccatg
     1381 aatatcgata tctaggaaat aaagctgatt tacttcatca ttttcaatgt attcttcaaa
     1441 ttcacggact tttcccgttg tcttgtatga tattggaata ttcgattctt tcgaaatttc
     1501 atccaatatt ctctctagtc tcacttgatg ttcaataaca tcttctaaaa ttaaaacttt
     1561 cattcaaatt ccctcttaaa tctaatgatt tgtctaaatg tactgccttc catctctgtt
     1621 tctaaaataa tattgttgta cttatctagt agttctttca cattatttaa tccgactccg
     1681 cgatttcttc ccttagtgga gaatcctaag gcaaatagat ctcctgaagg agtcatcgtc
     1741 attttacatg aattctgaat cacaataact gtttcagttt ccatcttaat aactgctact
     1801 tccatctgct ttttatagct atcagccgat ccttcgacag cattattcaa taaaacgctc
     1861 atgatacgaa ccaaatccaa tagttcaatt ggaagcttgg taatcgtatc ttttacttcc
     1921 agtgtaaact ctacaccatt atttcgagca tagacaattg actgagcaac caaacttcgt
     1981 aaagctgagt cttctatgtt gttcaaatca aagtaagtgt acttatctga acgcaattta
     2041 tgatttgctt tgactaaaac ttcattgtaa attctgtcaa tttcctgtaa attaccactg
     2101 tcaattgcca tctgcatgct gacaagcatt ccagcataat catgtcgaaa accacggatt
     2161 tcattataca gaccaacaat ttcatctgtg taattctgta aatgtttctg ttcaaatttc
     2221 ttctgcttca aagcaatctc tttctccatt tgaactttat gagaattcat tgcaaagaag
     2281 gtcaaaagga gagagataaa gacaatagat gacaaaatac ttccaaaact attcaaatgt
     2341 ttaatcgtac ttaccatatc tgaaacgaaa gatacaatat gtagcaatag taaagcaaaa
     2401 aatacttttt tcaagaaagg ataaaggtag tcctcgtcaa aataggctag ttccaaatgg
     2461 aaatagtaaa tgatttttaa tgtaacaaaa taggttaaca ccgtcacaac gaaaaagaat
     2521 gggaaatgat attgtaaaac aaaattatct cctgttatag aggagaaagt tacggacaga
     2581 aagttatgag tgctctcata taaaagagat agtagtaaac ttaggaatag tcctctatcc
     2641 ctctcatact gtttcatcca tcgaaaatag gaatataatc ccaaaggaaa taaaaatctt
     2701 tcaatcccta acccatctaa atatagaata tataagggaa aatcaaatac tatttctgtt
     2761 agtaatgtat aagcaccaaa aacgaataat tcttttctat ttatttgacc tttacaaata
     2821 aaatggtaac tgtgactaat aattaaaaaa tgaacaataa ccgtcccaaa tccaaataaa
     2881 tccattactc tttcccctta tttcattact tttttctttg taaaataaaa tcacggaaga
     2941 attttgacaa cctcatctcc ccacctttaa tcttttgtaa gtctttttcc ttcaaagcta
     3001 caaactgttc caatttaact gtgtttttca taataaaatc tcctaaaatg ttttttcttg
     3061 taagctaact tacaaaaaac attatacaaa atggaatttc gttttagata aaattctctc
     3121 aactgtcatt tttttctccc aaagtgtact tttttaagaa aaaagccggg aaaattccca
     3181 gctttgctat tatattgatc ccagcaggat tcgaacctgc gaccgttcgc ttagaaggcg
     3241 aatgctctat ccagctgagc tatgagacct aatacaatta ttctaccaaa aattcaatta
     3301 aaagtcaatt ttctatttat ggtaggggaa tccctgctga atcgtaaaag cgcgatagat
     3361 ttgttcaaca agaactagtc tcattaactg atggggtaag gttaggcgac caaaactgac
     3421 agaaagattg gctctatttt ttacagatga tgacaatcct aaacttcccc caataataaa
     3481 agtaagagta gaaaatcctt ttatagaagt ttcttctaac tgcttactaa attcttctga
     3541 gaagaaagtt ttcccttcaa tggctaacac aataacgaaa tcacggtcag caatttttga
     3601 taaaattctc tgaccttcta tttctaaaat cttttgattt tctgattcac tggccttatc
     3661 tggtgttttt tcatctgata actcaatcat ttcaaactta gcaaatctag aaattcgttt
     3721 tgaatactct gcgataccat cttttaaata cttttctttc agtttcccaa ctgttacaac
     3781 tttaattttc atgactctat tctaacatat tctctatttt ttcacatctt attcacaaaa
     3841 taaaaaatag atttcaatta agaaaatcac agtttcaaaa gagttatcca cagtttgtgt
     3901 aaaacttttg tgtttaagtt ataattaagc tagtcagttt atactttcag taattcaaac
     3961 atatggaggc aaatatgaaa catctaaaaa cattttacaa aaaatggttt caattattag
     4021 tcgttatcgt cattagcttt tttagtggag ccttgggtag tttttcaata actcaactaa
     4081 ctcaaaaaag tagtgtaaac aactctaaca acaatagtac tattacacaa actgcctata
     4141 agaacgaaaa ttcaacaaca caggctgtta acaaagtaaa agatgctgtt gtttctgtta
     4201 ttacttattc ggcaaacaga caaaatagcg tatttggcaa tgatgatact gacacagatt
     4261 ctcagcgaat ctctagtgaa ggatctggag ttatttataa aaagaatgat aaagaagctt
     4321 acatcgtcac caacaatcac gttataaatg gcgccagcaa agtagatatt agattgtcag
     4381 atgggactaa agtacctgga gaaattgtcg gagctgacac tttctctgat attgctgtcg
     4441 tcaaaatctc ttcagaaaaa gtgacaacag tagctgagtt tggtgattct agtaagttaa
     4501 ctgtaggaga aactgctatt gccatcggta gcccgttagg ttctgaatat gcaaatactg
     4561 tcactcaagg tatcgtatcc agtctcaata gaaatgtatc cttaagatcg gaagatggac
     4621 aagctatttc tacaaaagcc atccaaactg atactgctat taacccaggt aactctggcg
     4681 gcccactgat caatattcaa gggcaggtta tcggaattac ctcaagtaaa attgctacaa
     4741 atggaggaac atctgtagaa ggtcttggtt tcgcaattcc tgcaaatgat gctatcaata
     4801 ttattgaaca gttagaaaaa aacggaaaag tgacgcgtcc agctttggga atccagatgg
     4861 ttaatttatc taatgtgagt acaagcgaca tcagaagact caatattcca agtaatgtta
     4921 catctggtgt agttgttcgt tcggtacaaa gtaatatgcc tgccaatggt caccttgaaa
     4981 aatacgatgt aattacaaaa gtagatgaca aagagattgc ttcatcaaca gacttacaaa
     5041 gtgctcttta caaccattct atcggagaca ccattaagat aacctactat cgtaacggga
     5101 aagaagaaac tacctctatc aaacttaaca agagttcagg tgatttagaa tcttgattga
     5161 catctatgta aagaaagctt tacataagag aaaagatgtg ttagtgtaga atcatggaaa
     5221 aatttgaaat gatttctatc acagatatac aaaaaaatcc ctatcaaccc cgaaaagaat
     5281 ttgatagaga aaaactagat gaactagcac agtctatcaa agaaaatggg gtcattcaac
     5341 cgattattgt tcgtcaatct cctgttattg gttatgaaat ccttgcagga gagagacgct
     5401 atcgggcttc acttttagct ggtctacggt ctatcccagc tgttgttaaa cagatttcag
     5461 accaagagat gatggtccag tccattattg aaaatttaca gagagaaaat ttaaacccaa
     5521 tagaagaagc acgcgcctat gaatctctcg tagagaaagg attcacccat gctgaaattg
     5581 cagataagat gggcaagtct cgtccatata tcagcaactc cattcgttta ctttccttgc
     5641 cagaacagat tctctcagaa gtagaaaatg gcaaactatc acaagcccat gcgcgttccc
     5701 tagttgggtt aaataaggaa caacaagact atttctttca acggattata gaagaagata
     5761 tttctgtaag gaagttagaa actcttctga cagagaaaaa acaaaagaaa cagcaaaaaa
     5821 ctaatcattt catacaaaat gaagaaaaac agttaagaaa actactcggt ttagatgtag
     5881 aaattaaact atctaaaaaa gacagtggaa aaatcattat ttctttttca aatcaagaag
     5941 aatatagtag aattatcaac agcctgaaat aaggctgttc ttttattttt ttatctcaca
     6001 aggttatcca ctatgttttt cgataaaaag cttaataaat caataatttc ttcttttatc
     6061 cccaacctgt ggataaagtt tggtaacatt gtggattatt tttcacagct tgtggaaaat
     6121 tcttgctatc tatggtaaaa tatctctagt attaaacttt taaatagtaa aggaggagaa
     6181 aggattgaaa gaaaaacaat tttggaatcg tatattagaa tttgcacaag aaagactgac
     6241 tcgatccatg tatgatttct atgctattca agctgaactc atcaaggtag aggaaaatgt
     6301 tgccactata tttctacctc gctctgaaat ggaaatggtc tgggaaaaac aactaaaaga
     6361 tattattgta gtagctggtt ttgaaattta tgacgctgaa ataactcccc actatatttt
     6421 caccaaacct caagatacga ctagctcaca agttgaagaa gctacaaatt taactcttta
     6481 tgactatagt ccaaagttag tatctattcc ttattcagat acgggattaa aagaaaagta
     6541 tacctttgat aattttattc aaggggatgg aaatgtttgg gctgtatcag ccgctttagc
     6601 tgtctctgaa gatttggctc tgacctataa ccctcttttt atctatggag gaccaggcct
     6661 tggtaagact cacttattaa acgctattgg aaatgaaatt ctaaaaaata ttcctaatgc
     6721 gcgtgttaaa tatatccctg ccgaaagctt tattaatgac tttcttgatc acctaagact
     6781 tggggaaatg gaaaagttta aaaagaccta tcgtagtctt gatcttttgt taatcgatga
     6841 tatacagtca ctcagcggaa aaaaagtcgc aactcaggaa gaatttttca atacctttaa
     6901 cgcccttcat gacaagcaaa aacagattgt cctaacgagt gatcgtagtc caaaacatct
     6961 agaagggctc gaggagaggc ttgtcacgcg ttttagttgg ggattgacac aaactatcac
     7021 accccctgac tttgaaacac gtattgccat tttacaaagt aagacggaac atttaggcta
     7081 caatttccaa agtgatactc tagaatacct agctgggcaa tttgattcaa atgttcgaga
     7141 tcttgaggga gccatcaacg acatcacttt aattgccaga gtaaaaaaaa tcaaggatat
     7201 cactattgat attgctgcag aagccattag agcccgcaaa caagatgtta gccaaatgct
     7261 cgtcatccca attgataaaa tccaaactga agttggtaac ttttatggtg ttagtatcaa
     7321 agaaatgaag ggaagtagac gccttcaaaa tattgttttg gcccgtcaag tagccatgta
     7381 tttatctaga gaactaacag ataatagtct tccaaaaatt gggaaggaat ttgggggaaa
     7441 agatcatacc acagtcattc atgcccatgc caaaataaaa tctttgattg atcaagacga
     7501 taatttacgt ttagaaattg aatcaatcaa aaagaaaatc aaataatttg tggataactt
     7561 ttagtttttt atctttttta tccacatttt ttaaacaagc taaaaaactt gatatgactt
     7621 gtttaaaggc tgttttccac agatttcaca gactctatta ttactattat ctttctaata
     7681 ctaaaaataa ataaaggaga atccatgatt catttttcaa t
//
LOCUS       DAVLXH010000077         7313 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00028199
            SAMN33607166-rid17955573.denovo.078, whole genome shotgun sequence.
ACCESSION   DAVLXH010000077 DAVLXH010000000
VERSION     DAVLXH010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607166
            Sequence Read Archive: SRR23725544
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7313)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7313)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721421.1
            Genome Coverage       :: 115x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:42:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,210
            CDSs (total)                      :: 2,161
            Genes (coding)                    :: 2,023
            CDSs (with protein)               :: 2,023
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 73 of 138
            Pseudo Genes (incomplete)         :: 60 of 138
            Pseudo Genes (internal stop)      :: 40 of 138
            Pseudo Genes (multiple problems)  :: 31 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7313
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607166-rid17955573.denovo.078"
                     /strain="AUSMDU00028199"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1349"
     gene            <1..139
                     /locus_tag="VYO11_001991"
     CDS             <1..139
                     /locus_tag="VYO11_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HEV1596487.1"
                     /translation="ARNIKTSSDIELESDVDGDKSDNLPVDIKILGQHIEVYSVPKKQ
                     S"
     gene            339..3614
                     /gene="rexB"
                     /locus_tag="VYO11_001992"
     CDS             339..3614
                     /gene="rexB"
                     /locus_tag="VYO11_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent nuclease subunit B"
                     /protein_id="HEV1596488.1"
                     /translation="MKLLYTDIRTSLTEILTREAEELVAAGKRVFYIAPNSLSFEKER
                     AVLECLSQQASFSITVTRFAQMARYLVLNDLPAKTTLDDIGLGLAFYKCLAELDPKDL
                     RVYSAIKQDPQLIQQLIELYHEMTKSQMSFLDLENLTDEDKRADLLLIFEKVTAYLNQ
                     GQLAQGSQLSHLIEAIENDKVSSDFNQITLVIDGFTRFSAEEERVVDLLHGKGVEIVI
                     GAYASKKAYTSPFSEGNLYQASVKFLHHLASKYQTPAQDCSQTHEKMDSFDKASRLLE
                     SSYDFSELALDVDEKDRENLQIWSCLTQKEELELVARSIRQKLHENSDLSYKHFRILL
                     GDVASYQLSLKTIFDQYQIPFYLGRSEAMAHHPLTQFVESILALKRYRFRQEDLINLL
                     RTDLYTDLSQSDIDAFEQYIRYLGINGLPAFQQTFTKSHHGKFNLERLNVLRLRILAP
                     LETLFASRKQKAEKLLQKWSVFLKEGAVTKQLQDLTTTLEAVEQERQAEVWKAFCHVL
                     EQFATVFAGSQVSLEDFLALLHSGMSLSQYRTIPATVDTVLVQSYDLIAPLTADFVYA
                     IGLTQDNLPKISQNTSLLTDEERQNLNQATEEGVQLLIASSENLKKNRYTMLSLVNSA
                     RKQLFLSAPSLFNESESKESAYLQELIHFGFRRREKRMNHKGLSKEDMGSYHSLLSSL
                     VAYHQQGEMSDTEQDLTFVKVLSRVIGKKLDQQGLENPAIPISPSSKTLAKDTLQALY
                     PAKQEFYLSTSGLTEFYRNEYSYFLRYVLGLQEELRLRPDARSHGNFLHRIFERALQL
                     PNEDSFDQRLEQAIQETSQEREFEAIYQESLEAQFTKEVLLDVARTTGHILRHNPAIE
                     TIKEEANFGGKDQAFIQLDNGRSVFVRGKVDRIDRLKANGAIGVVDYKSSLTQFQFPH
                     FFNGLNSQLPTYLAALKREGEQNFFGAMYLEMAEPVQSLMAVKSLAGAVVEASKSMKY
                     QGLFLEKENSYLGEFYNKNKANQLTDEEFQLLLDYNAYLYKKAAEKILAGRFAINPYT
                     ENGRSIAPYVQQHQAITGFEANYHLGQARFLKKLDLADGKRLVGEKLKQAWFEKIREE
                     LNR"
     gene            3611..7261
                     /gene="addA"
                     /locus_tag="VYO11_001993"
     CDS             3611..7261
                     /gene="addA"
                     /locus_tag="VYO11_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HEV1596489.1"
                     /translation="MKLIPFLSEEEIQKLQEAEANSSKEQKKTAEQIEAIYTSGQNIL
                     VSASAGSGKTFVMAERILNQLARGVEISQLFISTFTVKAATELKERLEKKISKKIQET
                     DDVDLKQHLGRQLADLPNAAIGTMDSFTQKFLGKHGYLLDIAPNFRILQNQSEQLLLE
                     NEVFHEVFEAHYQGKQKETFSHLLKNFAGRGKDERGLRQQVYKIYDFLQSTSNPQKWL
                     SESFLKGFEKADFTSEKEKLTEQIKQALWDLESFFRYHLDNDAKEFAKAAYLENVQLI
                     LDEIGSLNQESDSQAYQAVLARVVAISKEKNGRALTNASRKADLKPLADAYNEERKTQ
                     FAKLGQLSDQITILDYQERYHQDTWELAKTFQTFMSHFVEAYRQRKRQENAFEFADIS
                     HYTIEILENFPQVRESYQERFHEVMVDEYQDTNHIQERMLELLSNGHNRFMVGDIKQS
                     IYRFRQADPQIFNEKFQRYAQNPQKGKLILLKENFRSSSEVLSATNDVFERLMDQEVG
                     EINYDNKHQLVFANTKLTPNPDNKAEFLLYDKDDTGEEEESQTETKLTGEMRLVIKEI
                     LKLHQEKGVAFKEIALLTSSRSRNDQILLALSEYGIPVKTDGEQNNYLQSLEVQVMLD
                     TLRVIHNPLQDYALVALMKSPMFGFDEDELARLSLQKAEDKVHENLYEKLVNAQKMAS
                     SQKGLIHTALAEKLKQFMDILASWRLYAKTHSLYDLIWKIYNDRFYYDYVGALPNGPA
                     RQANLYALALRADQFEKSNFKGLSRFIRMIDQVLEAQHDLASVAVAPPKDAVELMTIH
                     KSKGLEFPYVFILNMDQDFNKQDSMSEVILSRQNGLGVKYIAKMETGAVEDHYPKTIK
                     LSIPSLTYRQNEEELQLASYSEQMRLLYVAMTRAEKKLYLVGKGSREKLEAKQYPAAK
                     NGKLNSNTRLQARNFQDWLWAISKVFTKDKLNFSYRFIGEDQLTREAIGELETKSPLQ
                     DSSQADNRQSDTIKEALKMLKEVEVYNTLHRAAIELPSVQTPSQIKKFYEPVMDMEGV
                     EIAGQGQSVGKKISFDLPDFSTKEKVTGAEIGSATHELMQRIDLSQQLTLASLTETLK
                     QVQTSQAVRDKINLDKILAFFDTVLGQEILANTDHLYREQPFSMLKRDQKSQEDFVVR
                     GILDGYLLYENKIVLFDYKTDRYDEPSQLVDRYRGQLALYEEALSRAYSIENIEKYLI
                     LLGKDEVQVVKV"
BASE COUNT         2220 a         1557 c         1565 g         1971 t
ORIGIN      
        1 ggcacgtaat attaaaactt cttctgatat cgaattagag tccgatgttg atggcgataa
       61 atcagacaat ctaccagtcg acattaagat actgggacaa cacattgaag tgtattccgt
      121 acctaagaaa caatcataaa actcaaagcc ttgttaccga ggctttttta ttatgtgatt
      181 ttcagtagcc agacttattc tatctaatac aagtaaagct aagtatttaa gatttagcag
      241 atgatgaaga aaagaaagga tggcctaaat attttaacag atttacgagg ctaatcatgg
      301 tataatatag ggtgatgaaa aattccaacg aggctgagat gaaattactt tatactgata
      361 ttcggacttc tttgacagaa attctaacaa gagaggcaga agagctagtt gcagctggca
      421 agcgggtctt ctacattgcc cccaactctc tttcttttga aaaggaacgc gccgtgctgg
      481 aatgcttgtc ccagcaggct tctttttcga ttaccgtcac gcgctttgct caaatggctc
      541 gttatctggt cttgaatgat ttaccagcta aaactactct tgatgatatc ggtcttgggt
      601 tggcctttta caaatgcctt gccgaactcg atcccaagga cttgcgtgtt tatagcgcta
      661 ttaagcagga tcctcaattg atccagcagt taattgagct ttaccatgag atgaccaaat
      721 cccagatgag ttttttggac ttggagaatt taacagatga ggataagagg gcggatttac
      781 tcttgatttt tgagaaagta acagcctatc ttaatcaagg tcagttagcc cagggaagtc
      841 agttgtccca tttgattgag gctattgaga atgacaaggt aagtagtgat tttaatcaaa
      901 tcaccttggt cattgacggc tttactcgtt tttctgctga ggaagagcgg gttgtggact
      961 tacttcacgg caaaggtgtt gagattgtta tcggggctta tgctagtaag aaagcctata
     1021 ccagtccttt tagcgagggc aatctctacc aagccagcgt aaaatttctc catcatctgg
     1081 cttctaaata ccaaacgcct gctcaggact gttctcaaac tcatgagaag atggatagtt
     1141 ttgacaaggc ctctcgtttg ttggagtctt cttatgactt ttcagaactc gctttggatg
     1201 tcgatgagaa agaccgtgaa aatttacaaa tctggtcttg tttgacgcaa aaggaggagt
     1261 tggagctagt agcccgtagt attcgtcaga aattacatga gaactcagac ctgagctaca
     1321 agcattttcg tattctcttg ggggatgtag cttcttacca gttatctctc aaaaccattt
     1381 ttgaccagta tcagattcct ttttatcttg gtagaagcga agccatggct catcatccct
     1441 tgactcagtt tgtcgagtct attttagctt taaaacgtta ccgttttcgt caggaggatt
     1501 tgattaatct tcttagaact gatttgtata ctgacctcag tcagtctgat attgatgctt
     1561 ttgagcaata tatccgctat cttggtatca atggcttgcc agcctttcag caaaccttca
     1621 ccaaatccca ccatggaaaa tttaatcttg agcgtttgaa tgtcctccgc ctgagaattt
     1681 tagcacctct tgaaaccctc tttgccagcc gaaaacaaaa ggctgaaaaa ctcctacaaa
     1741 aatggagtgt ctttctaaaa gaaggagctg tgaccaagca gttacaagat ttgacaacca
     1801 ctttggaagc tgtagaacag gaaagacaag ccgaagtttg gaaggctttc tgccatgttt
     1861 tagaacaatt tgcgactgtt tttgctggtt cacaggttag tctggaagac ttcctagcct
     1921 tgctccattc tggaatgagt ttgtcccaat accgtaccat tccagcaaca gtggacactg
     1981 ttctggtgca gagttacgat ttgattgcac cattgactgc tgactttgtc tatgctattg
     2041 gactaactca ggacaattta ccaaaaattt ctcaaaacac cagtcttctg acagatgaag
     2101 aaaggcaaaa tctaaaccaa gcgaccgaag aaggcgttca attactgatt gccagcagtg
     2161 aaaatctcaa gaaaaatcgc tacactatgc tttccttggt caattctgct cgtaagcagt
     2221 tgttcttgtc ggctccaagc ctttttaacg aaagtgaaag taaggaatct gcctatcttc
     2281 aagagttgat ccattttgga tttaggcgga gagagaagag gatgaatcac aaaggactgt
     2341 ctaaggagga tatggggtcc tatcacagtc ttttgtctag tctggttgcc tatcaccagc
     2401 agggtgagat gagcgatact gagcaagatt tgacttttgt caaggttctg tcgcgtgtca
     2461 taggtaaaaa actagatcag caaggtctgg aaaatccagc catcccaatc agtccaagca
     2521 gcaagacctt agccaaggac accttgcaag ctctctatcc tgccaaacag gagttttacc
     2581 tgtctacgtc gggtttgaca gagttttatc gcaatgaata cagttatttc ctacgctacg
     2641 ttttaggctt gcaggaggaa ttacgtttgc gtcctgatgc ccgtagtcac gggaatttct
     2701 tgcatcgtat ctttgaacgc gccttacagt tgcctaatga agattccttt gaccaacgtc
     2761 tagaacaagc tattcaagaa accagtcaag aacgcgaatt tgaagctatt tatcaagaaa
     2821 gtttggaagc ccagtttacc aaggaagttt tgcttgatgt tgcacggacg actggacata
     2881 ttctccgaca caatccagcc atcgaaacca tcaaagaaga agcaaatttt ggtggaaaag
     2941 accaagcctt tattcaatta gacaatggac gcagtgtctt tgtacgaggc aaggtggacc
     3001 ggattgaccg tttgaaagct aatggagcga taggagtagt agactacaaa tccagtctga
     3061 ctcagttcca gtttcctcat ttctttaatg ggctcaattc tcagttacca acctatcttg
     3121 ctgccctaaa aagagaaggg gagcagaact ttttcggcgc catgtacttg gaaatggctg
     3181 aacctgtcca atctctgatg gcggtaaaaa gtctggcagg agcagtggta gaagccagca
     3241 aatctatgaa ataccaaggg ctcttcttgg aaaaagaaaa cagttattta ggcgaatttt
     3301 ataacaaaaa caaggctaat caactgacag atgaggaatt tcagctccta ctggactaca
     3361 atgcctatct ttacaagaaa gctgctgaga agattttagc aggccggttc gccatcaatc
     3421 cttatactga aaatggcaga agcattgccc catacgtcca gcaacatcag gctattacag
     3481 gctttgaagc caattaccat ctgggccaag cccgtttcct aaaaaagttg gacctagctg
     3541 atggcaagcg tctggtcgga gaaaaactca agcaagcttg gtttgaaaaa ataagagagg
     3601 agttaaatcg atgaagctta ttcccttttt aagtgaggag gagattcaaa aactgcaaga
     3661 agcagaagca aattcgagca aggaacaaaa gaaaactgcc gagcaaatcg aagctatcta
     3721 cacttctggc cagaatatcc tggtctcagc atcggctggt tctggaaaga cctttgtcat
     3781 ggcagagcgc attctgaacc aattggcgcg tggtgtcgaa atttctcaac tctttatctc
     3841 aacctttacc gtcaaggctg caactgaact taaagaacgt ttagagaaaa aaatcagcaa
     3901 gaaaattcaa gaaacagatg atgtcgacct caaacaacac ttgggacgcc agttggcaga
     3961 cttaccaaac gctgccattg gaaccatgga ctctttcaca caaaaattcc ttggcaaaca
     4021 tggttatctg cttgatattg cacctaattt ccgtatttta caaaaccaaa gcgagcaact
     4081 tcttctcgaa aacgaagtct ttcatgaggt ctttgaagcg cattaccaag gtaaacagaa
     4141 agagaccttt agtcatttgc tgaaaaactt tgctgggcgt ggcaaggacg aacggggtct
     4201 gcgccagcag gtctataaaa tctatgactt cctccaatcc accagtaatc ctcaaaagtg
     4261 gttgagtgaa tctttcctca aaggctttga gaaagctgat tttaccagtg aaaaagaaaa
     4321 actgactgag caaatcaaac aagccctttg ggatttggaa agctttttcc gttaccatct
     4381 ggataacgat gccaaggagt ttgcaaaggc tgcctattta gaaaatgttc agttaattct
     4441 ggatgaaatt ggctccctaa atcaggagtc cgatagtcag gcttatcagg cagtgcttgc
     4501 gcgtgttgtc gccatctcta aggagaaaaa cggtcgagct ctgactaatg ccagtcgtaa
     4561 ggctgatttg aagcccctgg ctgatgccta caacgaagag agaaagaccc agtttgctaa
     4621 actaggacaa ttatcagacc agataaccat tctcgactat caagaacgtt atcatcaaga
     4681 cacatgggaa ctagctaaaa ccttccaaac ctttatgagt cattttgtgg aggcttatcg
     4741 tcagcgcaaa cgccaggaaa atgcctttga attcgctgat atcagccatt acaccattga
     4801 gattttagag aatttcccac aagttcgtga gtcttatcag gagcgcttcc atgaagtcat
     4861 ggtcgatgag tatcaggata ccaaccatat tcaagaacgg atgctggaat tgttgtctaa
     4921 tggccacaat cgctttatgg tgggagatat caagcaatcc atctatcgtt tccgtcaggc
     4981 agacccgcag attttcaatg agaaattcca acgctatgcg caaaatcccc aaaaaggcaa
     5041 gctcattctc ctcaaggaaa atttccgtag tagttcagaa gtgctgtcag caaccaatga
     5101 tgtctttgaa cgtctcatgg accaagaggt cggcgaaatc aactatgata acaagcacca
     5161 gcttgttttt gccaatacca aactgactcc caatccagac aacaaggcag aatttctcct
     5221 ctacgacaag gacgatacag gtgaggaaga agagagtcaa acagaaacga aactaacagg
     5281 cgaaatgcgc ttagttatca aggagattct gaaacttcat caagaaaaag gtgttgcctt
     5341 taaggaaatt gcccttctga cctccagccg cagtcgtaat gaccagattc tcctcgccct
     5401 gtctgagtac ggaattcctg tcaaaactga cggagagcaa aacaattatc tccaatccct
     5461 agaagtgcaa gtcatgctag acactcttcg tgtcattcac aatcccctgc aagactacgc
     5521 cttggttgcc cttatgaagt ctccaatgtt tggttttgat gaggatgagc tagcacgttt
     5581 gtcccttcag aaagcagagg ataaagtcca cgaaaatctc tatgaaaaac tggtcaatgc
     5641 acaaaaaatg gcaagtagtc aaaaaggttt gattcacaca gctctagctg aaaaactaaa
     5701 gcaattcatg gatatcctag cttcttggcg cttgtatgcc aaaacccact ctctctatga
     5761 cttgatttgg aagatttaca acgaccgttt ttattatgac tatgttgggg ctttgccgaa
     5821 tggtcctgct aggcaggcca atctctatgc cctagcactg cgtgctgatc aatttgaaaa
     5881 gagcaatttc aaaggtttgt cgcgttttat tcgtatgatt gaccaagtct tagaagccca
     5941 gcacgatttg gcaagcgtgg ccgtcgcacc gccaaaagat gcagtagagc tcatgaccat
     6001 ccacaagagt aaggggctgg agtttcctta cgtctttatc ctcaatatgg atcaagattt
     6061 caacaagcaa gactctatgt cagaagtcat tctcagtcgt cagaatggtc ttggtgtcaa
     6121 atatattgcc aagatggaga caggggcagt agaagaccac tatcctaaaa ccatcaaact
     6181 ctccattcct agcctgacct ataggcagaa tgaagaggaa ttacagctag caagctattc
     6241 tgagcagatg cgtttgctgt atgttgctat gacgcgggct gagaaaaagc tctatcttgt
     6301 cggcaagggt tctcgtgaaa agctggaagc caagcaatac ccagcagcca aaaatgggaa
     6361 actaaatagc aatactagac tgcaagcacg gaatttccaa gattggcttt gggctatcag
     6421 taaagtgttt actaaggaca agctcaactt tagttatcgt tttattggcg aagatcagtt
     6481 gaccagagaa gctatcggag agttggaaac caagagtcct ctccaagata gctcccaagc
     6541 agacaatcgt cagtcagata ccatcaaaga agctctgaaa atgctgaagg aggtggaagt
     6601 ttataatact cttcaccgcg cagctattga acttcctagt gttcaaaccc caagtcaaat
     6661 caagaaattc tacgaaccag ttatggatat ggaaggtgtc gagattgctg gtcaaggtca
     6721 gtcagtaggc aagaaaatca gcttcgattt gccagatttt tcaacaaaag aaaaggtaac
     6781 tggagctgag attggtagtg ctactcacga actcatgcag agaattgacc tcagccagca
     6841 actaaccctt gctagcctaa cagaaacact caaacaagtt caaactagcc aagctgtcag
     6901 agacaagatc aatcttgata aaattcttgc tttctttgac acagtactcg gtcaggaaat
     6961 tcttgctaat accgaccatc tctatcgcga gcaacctttc tccatgctca aacgagacca
     7021 aaagagtcag gaagactttg ttgtccgtgg tatccttgat ggctatctgc tttacgaaaa
     7081 caaaattgtt ctgttcgact acaagacaga ccgctatgat gaaccaagtc aactcgtaga
     7141 ccgctatcgt ggtcagttag ctctatacga agaggcttta tcacgagcct attcgattga
     7201 aaatattgaa aaatacttga ttttactcgg taaagacgag gttcaagttg taaaagtata
     7261 acttatactc tttgaaaatc tcttcaaacc acgtcagctt cgccttgctg tat
//
LOCUS       DAVLXH010000078         7274 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00028199
            SAMN33607166-rid17955573.denovo.079, whole genome shotgun sequence.
ACCESSION   DAVLXH010000078 DAVLXH010000000
VERSION     DAVLXH010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607166
            Sequence Read Archive: SRR23725544
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7274)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7274)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721421.1
            Genome Coverage       :: 115x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:42:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,210
            CDSs (total)                      :: 2,161
            Genes (coding)                    :: 2,023
            CDSs (with protein)               :: 2,023
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 73 of 138
            Pseudo Genes (incomplete)         :: 60 of 138
            Pseudo Genes (internal stop)      :: 40 of 138
            Pseudo Genes (multiple problems)  :: 31 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7274
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607166-rid17955573.denovo.079"
                     /strain="AUSMDU00028199"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1349"
     gene            151..5091
                     /locus_tag="VYO11_001994"
     CDS             151..5091
                     /locus_tag="VYO11_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000795197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterial Ig-like domain-containing protein"
                     /protein_id="HEV1596490.1"
                     /translation="MKNPFFERRCRYSIRKLSVGACSLMIGAVLFAGPALAEETAVPE
                     NSGANTELVSGESEHSTNEADKQNEGEHTRENKLEKAEGVATASETAEAASAAKPEEK
                     ASEAVAETPSAEAKPKSDKETEAKPEATNQGDESKPAAEANKTEKEVQPDVPKNTEKT
                     LKPKEIKFNSWEELLKWEPGAREDDAINRGSVVLASRRTGHLVNEKASKEAKVQALSN
                     TNSKAKDHASVGGEEFKAYAFDYWQYLDSMVFWEGLVPTPDVIDAGHRNGVPVYGTLF
                     FNWSNSIADQERFAEALKQDADGSFPIARKLVDMAKYYGYDGYFINQETTGDLVKPLG
                     EKMRQFMLYSKEYAAKVNHPIKYSWYDAMTYNYGRYHQDGLGEYNYQFMQPEGDKVPA
                     DNFFANFNWDKTKNDYTIATANWIGRNPYDVFAGLELQQGGSYKTKVKWNDILDENGK
                     LRLSLGLFAPDTITSLGKTGEDYHKNEDIFFTGYQGDPTGQKPGDKDWYGIANLVADR
                     TPAVGNTFTTSFNTGHGKKWFVDGKVSKDSEWNYRSVSGVLPTWRWWQTSTGEKLRAE
                     YDFTDAYNGGNSLKFSGDVAGKTDQDVRLYSTKLEVTEKTKLRVAHKGGKGSKVYMAF
                     STTPDYKFDDADAWKELTLSDNWTNEEFDLSSLAGKTIYAVKLFFEHEGAVKDYQFNL
                     GQLTISDNHQEPQSPTSFSVVKQSLKNAQEAEAVVQFKGNKDADFYEVYEKDGDSWKL
                     LTGSSSTTIYLPKVSRSASAQGTTQELKVVAVGKNGVRSEAATTTFDWGMTVKDTSLP
                     KPLAENIVPGATVIDSTFPKTEGGEGIEGMLNGTITSLSDKWSSAQLSGSVDIRLTKP
                     RTVVRWVMDHAGAGGESVNDGLMNTKDFDLYYKDADGEWKLAKEVRGNKAHVTDITLD
                     KPITAQDWRLNVVTSDNGTPWKAIRIYNWKMYEKLDTESVNIPMAKAAARSLGNNKVQ
                     VGFADVPAGATITVYDNPNSQTPLATLKSEVGGDLASAPLDLTNQSGLLYYRTQLPGK
                     EISNVLAVSVPKDDRRIKSVSLETGPKKTSYAEGEDLDLRGGVLRVQYEGGTEDELIR
                     LTHAGVSVSGFDTHHKGEQNLTLQYLGQPVNANLSVTVTGQDEASPKTILGIEVSQEP
                     KKDYLVGDSLDLSEGRFAVAYSNDTMEEHSFTDEGVEISGYDAQKTGRQTLTLRYQGH
                     EVNFDVLVSPKAALNDEYLKQKLAEVEAAKNKVVYNFASPEVKEAFLKAIEAAEQVLK
                     DHETSTQDQVNDRLNKLTEAHKALNGQEKFTEEKTELDRLTGEAQELLAAKPNHPSGS
                     ALAPLLEKNKALVEKVDLSPEELATAKQSLKDLVALLKEDKSAVFSDSKTGVEVHFSN
                     KEKTVIKGLKVERVQASAEEKKYFAGEEAHVFEIEGLDEKGQDVDPSYASIVKIPIEK
                     DKKVKKVFFLPEGKEAVELAFEQTDSHVIFTAPHFTHYAFVYESAEKPQPAKPAPQNT
                     VLPKPTYQPASDQQKAPKLEVQEEKVAFHRQEHENAEMLVGEQRVIIQGRDGLLRHVF
                     EVDENGQRRLRSTEVIQEAIPEIVEIGTKVKTVPAVVATQEKPAQNTAVKSEEASKQL
                     PNTGTADANEALIAGLASLGLASLALTLRRKREDKD"
     gene            5181..6377
                     /locus_tag="VYO11_001995"
     CDS             5181..6377
                     /locus_tag="VYO11_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HEV1596491.1"
                     /translation="MAKLTVKDVDLKGKKVLVRVDFNVPLKDGVITNDNRITAALPTI
                     KYIIEQGGRAILFSHLGRVKEEADKAGKSLAPVAADLAAKLGQDVVFPGVTRGAELEA
                     AINALEDGQVLLVENTRYEDVDGKKESKNDPELGKYWASLGDGIFVNDAFGTAHRAHA
                     SNVGISANVEKAVAGFLLENEIAYIQEAVETPERPFVAILGGSKVSDKIGVIENLLEK
                     ADKVLIGGGMTYTFYKAQGIEIGNSLVEEDKLDVAKALLEKANGKLILPVDSKEANAF
                     AGYTEVRDTEGEAVSEGFLGLDIGPKSIAKFDEALTGAKTVVWNGPMGVFENPDFQAG
                     TIGVMDAIVKQPGVKSIIGGGDSAAAAINLGRADKFSWISTGGGASMELLEGKVLPGL
                     AALTEK"
     gene            complement(6451..>7274)
                     /locus_tag="VYO11_001996"
     CDS             complement(6451..>7274)
                     /locus_tag="VYO11_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001856869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ISL3-like element IS1167A family transposase"
                     /protein_id="HEV1596492.1"
                     /translation="DFSRLPKIMSWDEYAFTKGKMSFIAQDFDNLNIITVLEGRTQAV
                     IRNHFLRYDRAVRCQVKIITMDMFSPYYDLAKQLFPCAKIVLDRFHIIQHLSRAMSRF
                     RVQIMNQFERKSHEYKAIKRYWKLIQQDSRKLSDKRFYRPTFRMHLTNKEILDKILSY
                     SEDLKHHYQIYQLLLFHFQNKDPEKFFGLIEDNLKQVHPLFQTVFKTFLKNKEKIVNA
                     LQLHYSNAKLEATNNLIKLIKRNAFGFRNFENFKKRIFIALNIKKERTKFVLSQA"
BASE COUNT         2382 a         1329 c         1632 g         1931 t
ORIGIN      
        1 ccttatttta gatttgtgaa aacagctatt gttttttgtc taaaaatgtt ttaggataaa
       61 aatgtgatta tcatggttct agagttaaaa aaccacagaa tataaagcgc tttcttaaaa
      121 acaacaaaat caatctttta ggaggagaaa atgaagaatc cattttttga aagacgttgt
      181 cgttacagta ttcgtaagtt atcagtagga gcctgctcgc tgatgattgg tgctgtttta
      241 tttgctggtc cagccttggc tgaagaaact gcagttcctg aaaatagcgg agctaataca
      301 gagcttgttt caggagagag tgagcattcg accaatgaag ctgataagca gaatgaaggg
      361 gaacatacta gagaaaacaa gctagaaaag gcagaaggag tagcgacagc atctgaaact
      421 gcagaagcag ctagcgcagc taaaccagag gaaaaagcaa gtgaggcggt tgcagaaaca
      481 ccatctgcag aagcaaaacc taagtctgac aaggaaacag aagcaaagcc cgaagcaact
      541 aaccaagggg atgagtctaa gccagcagca gaagctaata agactgaaaa agaagtccag
      601 ccagatgtcc ctaaaaatac agaaaaaaca ttaaaaccaa aggaaatcaa atttaattct
      661 tgggaagaat tgttaaaatg ggaaccaggt gctcgtgaag atgatgctat taaccgcgga
      721 tctgttgtcc tcgcttcacg tcggacaggt catttagtca atgaaaaagc tagcaaggaa
      781 gcaaaagttc aagccttatc aaacactaat tctaaagcaa aagaccatgc ttctgttggt
      841 ggagaagagt tcaaggccta tgcttttgac tattggcaat atctagattc aatggtcttc
      901 tgggaaggtc tcgtaccaac tcctgacgtt attgatgcag gtcaccgtaa cggggttcct
      961 gtatacggta cactcttctt caactggtct aatagtattg cagatcaaga aagatttgct
     1021 gaagctttga agcaagacgc agatggtagc ttcccaattg cccgtaaatt ggtagacatg
     1081 gccaagtatt atggctatga tggctatttc atcaaccaag aaacaactgg agatttggtt
     1141 aaacctcttg gagaaaagat gcgccagttt atgctctata gcaaggaata tgctgctaag
     1201 gtaaaccatc caatcaagta ttcttggtac gatgccatga cctataacta tggacgttat
     1261 catcaagatg gtttgggaga atacaactac caattcatgc aaccagaagg agataaggtt
     1321 ccggcagata acttctttgc taactttaac tgggataaga ctaaaaatga ttacactatt
     1381 gcaactgcca actggattgg acgtaatcct tatgatgtat ttgcaggttt ggaattgcaa
     1441 cagggtggtt cctacaagac aaaggttaag tggaatgaca ttttagacga aaatgggaaa
     1501 ttgcgccttt ctcttggttt atttgcccca gataccatta caagtttagg aaaaactggt
     1561 gaagattatc ataaaaatga agatatcttc tttacaggtt atcaaggaga ccctactggc
     1621 caaaaaccag gtgacaaaga ttggtatggt attgctaacc tagttgcgga ccgtacgcca
     1681 gcggtaggta atacttttac tacttctttt aatacaggtc atggtaaaaa atggttcgta
     1741 gatggtaagg tttctaagga ttctgagtgg aattatcgtt cagtatcagg tgttcttcca
     1801 acatggcgct ggtggcagac ttcaacaggg gaaaaacttc gtgcagaata tgattttaca
     1861 gatgcctata atggcggaaa ttcccttaaa ttctctggtg atgtagccgg taagacagat
     1921 caggatgtga gactttattc tactaagtta gaagtaactg agaagaccaa acttcgtgtt
     1981 gcccacaagg gaggaaaagg ttctaaagtt tatatggcat tctctacaac tccagactac
     2041 aaattcgatg atgcagatgc atggaaagaa ctaacccttt ctgacaactg gacaaatgaa
     2101 gaatttgatc ttagctcact agcgggtaaa accatctatg cagtcaaact atttttcgag
     2161 catgaaggtg ctgtaaaaga ttatcagttc aacctaggac aattaactat ctcggacaat
     2221 caccaagagc cacaatcgcc gacaagcttt tctgtagtga aacaatctct taaaaatgcc
     2281 caagaagcgg aagcagttgt acaatttaaa ggcaacaagg atgcagattt ctatgaagtt
     2341 tatgaaaaag atggagacag ctggaaatta ctaactggct catcttctac aactatttat
     2401 ctaccaaaag ttagccgctc agcaagtgct cagggtacaa ctcaagaact gaaggttgta
     2461 gcagtcggta aaaatggagt tcgttcagaa gctgcaacca caacctttga ttggggtatg
     2521 actgtaaaag ataccagcct accaaaacca ctagctgaaa atatcgttcc aggtgcaaca
     2581 gttattgata gtactttccc taagactgaa ggtggagaag gtattgaagg tatgttgaac
     2641 ggtaccatta ctagcttgtc agataaatgg tcttcagctc agttgagtgg tagtgtggat
     2701 attcgtttga ccaagccacg taccgttgtt agatgggtca tggatcatgc aggggctggt
     2761 ggtgagtctg ttaacgatgg cttgatgaac actaaagact ttgaccttta ttataaagat
     2821 gcagatggtg agtggaagct agctaaggaa gtccgtggta acaaagcaca cgtgacagat
     2881 atcactcttg ataaaccaat cactgctcag gactggcgct tgaatgttgt cacttctgac
     2941 aatggaactc catggaaggc tattcgtatc tataactgga aaatgtatga aaagcttgat
     3001 actgagagtg tcaatattcc gatggccaag gctgcagccc gttctctagg caataacaag
     3061 gtacaagttg gctttgcaga tgtaccggct ggagcaacta ttaccgttta tgataatcca
     3121 aattctcaaa ctccgctcgc aaccttgaag agcgaagttg gaggagacct agcaagtgca
     3181 ccattggatt tgacaaatca atctggtctt ctttattatc gtacccagtt gccaggcaag
     3241 gaaattagta atgtcctagc agtttccgtt ccaaaagatg acagaagaat caagtcagtc
     3301 agcctagaaa caggacctaa gaaaacaagc tacgccgaag gggaggattt ggaccttaga
     3361 ggtggtgttc ttcgagttca gtatgaagga ggaactgagg acgaactcat tcgcctaact
     3421 cacgcaggtg tatcagtatc aggttttgat acgcatcata agggagaaca gaatcttact
     3481 ctccaatatt tgggacaacc agtaaatgct aatttgtcag tgactgtcac tggccaagat
     3541 gaagcaagtc cgaaaactat tttgggaatt gaagtaagtc aggaaccgaa aaaagattac
     3601 ctagttggtg atagcttaga cttgtctgaa ggacgctttg cagtggctta tagcaatgac
     3661 accatggaag aacattcctt tactgatgag ggagttgaaa tttctggtta cgatgctcaa
     3721 aagactggtc gtcaaacctt gacgcttcgt taccaaggtc atgaagtcaa ctttgatgtt
     3781 ttggtatctc caaaagcagc attgaacgat gagtacctca aacaaaaatt agcagaagtt
     3841 gaagctgcta agaacaaggt ggtctataac tttgcttcac cagaagtaaa agaagccttc
     3901 ttgaaagcaa ttgaagcggc cgaacaagtg ttgaaagacc atgaaactag cacccaagat
     3961 caagtcaatg accgacttaa taaattgaca gaagctcata aagctctgaa tggtcaagag
     4021 aaatttacgg aagaaaagac agagcttgat cgcttaacag gtgaggctca agaactcttg
     4081 gctgccaaac caaaccatcc ttcaggttct gccctagctc cgcttcttga gaaaaacaag
     4141 gccttggttg aaaaagtaga tttgagtcca gaagagcttg caacagcgaa acagagtcta
     4201 aaagatctgg ttgctttatt gaaagaagac aagtcagcag tcttttctga tagtaaaaca
     4261 ggtgttgaag tacacttctc aaataaagag aagactgtca tcaagggttt gaaagtagag
     4321 cgtgttcaag caagtgctga agagaagaaa tactttgctg gagaagaggc tcatgtcttt
     4381 gaaatagaag gtttggatga aaaaggtcaa gatgttgatc cctcttatgc ttctattgtg
     4441 aaaatcccaa ttgaaaaaga taagaaagtt aagaaagtat ttttcttacc tgaaggcaaa
     4501 gaggcagtag aattggcttt tgaacaaacg gatagtcatg ttatctttac agcacctcac
     4561 tttactcatt atgcctttgt ttatgaatct gctgaaaaac cacaacctgc taaaccagca
     4621 ccacaaaaca cagtccttcc aaaacctact tatcaaccgg cttctgatca acaaaaggct
     4681 cctaaattgg aagttcaaga ggaaaaggtt gcctttcatc gtcaagagca tgaaaatgct
     4741 gagatgctag ttggggaaca acgagtcatc atacagggac gagatggact gttaagacat
     4801 gtctttgaag ttgatgaaaa cggtcagcgt cgtcttcgtt caacagaagt catccaagaa
     4861 gcgattccag aaattgttga aattggaaca aaagtaaaaa cagtaccagc agtagtagct
     4921 acacaggaaa aaccagctca aaatacagca gttaaatcag aagaagcaag caaacaattg
     4981 ccaaatacag gaacagctga tgctaatgaa gccctaatag caggcttagc cagccttggt
     5041 cttgctagtt tagccttgac cttgagacgg aaaagagaag ataaagatta aatatcgaaa
     5101 aatcttgtga aatctttcct tatatttcca aagtgtgata taatagtttc gaataaaata
     5161 aataaaggag tttttgtaac atggcaaaac ttactgttaa agacgttgac ttgaaaggta
     5221 aaaaagtcct cgttcgtgtt gacttcaacg taccattgaa agatggcgta atcactaacg
     5281 ataaccgtat cacagcagct cttccaacta ttaagtacat catcgaacaa ggtggacgtg
     5341 caattctttt ctctcacctt ggacgtgtga aagaagaagc tgataaagct ggtaaatcac
     5401 ttgctcctgt agcagctgac ttggcagcaa aacttggtca agatgttgtt ttcccaggtg
     5461 tcactcgtgg tgctgaattg gaagcggcaa tcaacgctct tgaagatgga caagttctct
     5521 tggttgaaaa cactcgttac gaagatgttg acggcaagaa agaatctaaa aacgatcctg
     5581 aacttggtaa atactgggca tcacttggag atggtatctt cgtaaacgat gcattcggta
     5641 cagctcaccg tgcacacgca tctaacgttg gtatctcagc aaacgttgaa aaagcagttg
     5701 ctggtttcct tcttgaaaac gaaattgcct acatccaaga agcagttgaa actccagaac
     5761 gtccattcgt ggctatcctt ggtggttcaa aagtttcaga caagatcggt gttatcgaaa
     5821 acttgcttga aaaagctgat aaagtcctta tcggtggtgg gatgacttac acattctaca
     5881 aagcacaagg tatcgaaatc ggtaactcac ttgtagaaga agacaaattg gatgttgcga
     5941 aagctcttct tgaaaaagca aatggtaaat tgatcttgcc agttgactca aaagaagcta
     6001 acgcatttgc tggttacact gaagtgcgtg acactgaagg tgaagcagtt tctgaaggct
     6061 tccttggtct tgacatcggt ccaaaatcta tcgccaaatt tgacgaagct ttgactggtg
     6121 ccaaaacagt tgtatggaac ggacctatgg gtgtatttga aaacccagat ttccaagctg
     6181 gtacaatcgg tgtgatggac gctatcgtga aacaaccagg agttaaatca atcatcggtg
     6241 gtggtgactc agctgccgca gcgattaacc ttggccgtgc agacaagttc tcatggatta
     6301 gtacgggtgg tggagcatca atggaacttc ttgaaggtaa ggttcttcca ggacttgcag
     6361 ccttgacaga aaaataagat tttataaaca aatcaaagaa gagagggatg aaagttggct
     6421 ctttgtcaac tgtagtgggt tgaaaaaaag ctaagcttga gaaaggacaa atttcgtcct
     6481 ttcttttttg atattcaggg cgataaaaat ccgttttttg aagttttcaa agttccgaaa
     6541 accaaaggca ttgcgcttga taagtttgat gagattattg gtcgcttcca gtttggcatt
     6601 agaatagtgt agttgaaggg cgttgacgat tttctctttg ttctttagaa aggttttaaa
     6661 gacagtctga aaaagaggat gaacctgctt cagattgtcc tcaatgagtc cgaaaaattt
     6721 ctcagggtct ttgttctgaa agtgaaaaag taagagttga tagatctgat agtggtgttt
     6781 caagtcttct gaatagctta aaatcttgtc aagaatttct ttatttgtta agtgcatgcg
     6841 aaaagtaggg cgataaaaac gtttatcgct gagtttacga ctatcctgtt ggatgagttt
     6901 ccagtaacgc ttgatagcct tgtattcatg agattttcgt tcaaactgat tcataatttg
     6961 aacacgaaaa cgactcatgg cacggctgag atgttggata atatggaaac gatctagaac
     7021 gattttagca cacggaaaaa gctgtttagc caagtcatag taaggactaa acatatccat
     7081 cgtaatgatt ttcacttgac aacgaacggc tctatcgtag cgaagaaagt gatttcggat
     7141 gacagcttgt gttctgcctt caagaacagt gataatatta agattatcaa aatcttgcgc
     7201 aatgaaactc atctttccct tagtgaaggc atactcatcc caagacataa tctttggaag
     7261 ccgagaaaaa tcat
//
LOCUS       DAVLXH010000079         7175 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00028199
            SAMN33607166-rid17955573.denovo.080, whole genome shotgun sequence.
ACCESSION   DAVLXH010000079 DAVLXH010000000
VERSION     DAVLXH010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607166
            Sequence Read Archive: SRR23725544
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7175)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7175)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721421.1
            Genome Coverage       :: 115x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:42:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,210
            CDSs (total)                      :: 2,161
            Genes (coding)                    :: 2,023
            CDSs (with protein)               :: 2,023
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 73 of 138
            Pseudo Genes (incomplete)         :: 60 of 138
            Pseudo Genes (internal stop)      :: 40 of 138
            Pseudo Genes (multiple problems)  :: 31 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7175
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607166-rid17955573.denovo.080"
                     /strain="AUSMDU00028199"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1349"
     gene            1..483
                     /locus_tag="VYO11_001997"
                     /pseudo
     CDS             1..483
                     /locus_tag="VYO11_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="internal stop; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            569..1519
                     /locus_tag="VYO11_001998"
     CDS             569..1519
                     /locus_tag="VYO11_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HEV1596493.1"
                     /translation="MGKKRWARNGSESNDASYAQVVSLYDDTSISVSNNETDKVLTGS
                     LYTETNEQGLTIPSSLLKNWNEQTGKNLTTNDLIGKSVSASIVESAAETSKIAQFQTK
                     IVRVINDEDDMEDSNSFMLSHQIETILKEAGFTKAVSYFILELKDPSQTKVVTEELQK
                     NKKYTVFSQQRVLDIVITFIRVIQGLLIVLSSQAIVVAAVMIGIIIYINIMQRSKEIG
                     VMKAVGYQNRGVKGIFIYEAIWIVGIALLLAFLVAQGVGSLANAIVSHFYPSITKVFE
                     LNLLSVLGTLVFALLLGYVSAYFPARKISKMDPVESLRYE"
     gene            1696..2703
                     /gene="gap"
                     /locus_tag="VYO11_001999"
     CDS             1696..2703
                     /gene="gap"
                     /locus_tag="VYO11_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HEV1596494.1"
                     /translation="MVVKVGINGFGRIGRLAFRRIQNVEGVEVTRINDLTDPVMLAHL
                     LKYDTTQGRFDGTVEVKEGGFEVNGKFVKVSAERDPEQIDWATDGVEIVLEATGFFAK
                     KEAAEKHLKGGAKKVVITAPGGNDVKTVVFNTNHDVLDGTETVISGASCTTNCLAPMA
                     KALQDNFGVVEGLMTTIHAYTGDQMILDGPHRGGDLRRARAGAANIVPNSTGAAKAIG
                     LVIPELNGKLDGSAQRVPTPTGSVTELVAVLEKNVTVDEVNAAMKAASNESYGYTEDP
                     IVSSDIVGMSYGSLFDATQTKVLDVDGKQLVKVVSWYDNEMSYTAQLVRTLEYFAKIA
                     K"
     gene            complement(2770..3606)
                     /locus_tag="VYO11_002000"
     CDS             complement(2770..3606)
                     /locus_tag="VYO11_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000216776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEV1596495.1"
                     /translation="MTVKQLLEEQLLIPRKIRHFLRIKKHILINQEEVHWNEIVNPGD
                     VCQLTFDEEDYSQKTIPWGNPDLVQEVYQDQHLIIVNKPEGMKTHGNQPNEIALLNHV
                     STYVGQTCYVVHRLDMETSGLVLFAKNPFILPILNRLLEKKEISREYWALVDGNINRK
                     ELVFRDKIGRDRHDRRKRIVDAKNGQYAETHVSRLKQFSNKTSLARCKLKTGRTHQIR
                     VHLSHHNLPILGDPLYNSKSKTSRLMLHAFRLSFTHPLTLEKLTFTTLSNTFEKELKK
                     NG"
     gene            3732..5927
                     /locus_tag="VYO11_002001"
     CDS             3732..5927
                     /locus_tag="VYO11_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEV1596496.1"
                     /translation="MKLDKLFEKFLSLFKKETSELEDSDSTILRRSRSDRKKLAQVGP
                     IRKFWRRYHLTKIILILGLSAGLLVGIYLFAVAKSTNVNDLQNALKTRTLIFDREEKE
                     AGALSGQKGTYVELTDISKNLQNAVIATEDRSFYKNDGINYGRFFLAIVTAGRSGGGS
                     TITQQLAKNAYLSQDQTVERKAKEFFLALELSKKYSKEQILTMYLNNAYFGNGVWGVE
                     DASKKYFGVSASEVSLDQAATLAGMLKGPELYNPLNSVEDSTNRRDTVLQNMVAAGYI
                     DKNQETEAAEVDMASQLHDKYEGKISDYRYPSYFDAVVNEAVSKYNLTEEEIVNNGYR
                     IYTELDQNYQANMQVVYENTSLFPRAEDGTFAQSGSVALEPKTGGVRGVVGQVADNDK
                     TGFRNFNYATQSKRSPGSTIKPLVVYTPAVEAGWALNKQLDNHTMQYDSYKVDNYAGI
                     KTSREVPMYQALAESLNLPAVATVNDLGVDKAFEAGEKFGLNMEKVDRVLGVALGSGV
                     ETNPLQMAQAYAAFANEGLMPEAHFISRIENASGQVIASHKNSQKRVIDKSVADKMTS
                     MMLGTFTNGTGISSSPADYVMAGKTGTTEAVFNPEYTSDQWVIGYTPDVVISHWLGFP
                     TTDENHYLAGSTSNGAAHVFRNIANTILPYTPGSTFTVENAYKQNGIAPANTKRQVQT
                     NDNSQTDDNLSDIRGRAQSLVDEASRAISDAKIKEKAQTIWDSIVNLFR"
     gene            5980..6132
                     /gene="rpmG"
                     /locus_tag="VYO11_002002"
     CDS             5980..6132
                     /gene="rpmG"
                     /locus_tag="VYO11_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEV1596497.1"
                     /translation="MALKKASLACAVCGSRNYSIKISGNPKPTRLEVNKFCKHCGKYT
                     THRETR"
     gene            6142..6318
                     /gene="secE"
                     /locus_tag="VYO11_002003"
     CDS             6142..6318
                     /gene="secE"
                     /locus_tag="VYO11_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HEV1596498.1"
                     /translation="MRFIGDIFRLLKDTTWPTRKESWRDFRSIMEYTAFFVVIIYIFD
                     QLIVSGLIRFINIF"
     gene            6373..6909
                     /gene="nusG"
                     /locus_tag="VYO11_002004"
     CDS             6373..6909
                     /gene="nusG"
                     /locus_tag="VYO11_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000376740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HEV1596499.1"
                     /translation="MDSFDKGWFVLQTYSGYENKVKENLLQRAQTYNMLDNILRVEIP
                     TQTVQVEKNGKRKEVEENRFPGYVLVEMVMTDEAWFVVRNTPNVTGFVGSHGNRSKPT
                     PLLEQEIRDILVSMGQTVQEFDFDVEIGQTVRIIDGAFADYTGKITEIDNNKVKMIIS
                     MFGNDTVAEVNLNQIAEL"
     gene            7031..>7175
                     /locus_tag="VYO11_002005"
     CDS             7031..>7175
                     /locus_tag="VYO11_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1596500.1"
                     /translation="MIKELYEEVQGTVYKCRNEYYLHLWELSDWDQEGMLCLHELISR
                     EEGL"
BASE COUNT         2239 a         1239 c         1564 g         2133 t
ORIGIN      
        1 aattttaata gtttaaagca cctagcacct gtttagattg atgaaacagg attcgatact
       61 tatttttatc gagaatatgg tcgctcatta aaaggtcagt taagaagagg taaagtatct
      121 ggaagaagat atcagaggat ttctttggtt gcaggtctaa caaatggtga gttaatcgct
      181 ccaatgactt acgaagagat gatgacgagc gacttttttg aagcttggtt tcagaagttt
      241 ctcttaccaa cattaaccac accatcggtt attattatgg ataatgcaag attccataga
      301 atgggtaagt tagaactttt atgcgaggag tttgggcata aacttttacc tcttcctccc
      361 tactcacctg agtacaatcc tattgagaaa acatgggctc atatcaaaaa gcacctcaaa
      421 aaggtattac caagttgcaa taccttttat gaggctcttt tgtcctgctc ttgtttcaat
      481 tgactatagt tcacggatac agttgggaaa gaagctatta aatatttgga gagtcctttt
      541 gggatgaaca tgtcaaatat tactatagat gggcaagaaa agatgggcaa gaaatggatc
      601 tgagtcaaac gatgcttctt atgctcaagt agtgagtctt tatgatgata caagtatctc
      661 tgttagtaat aatgagacgg acaaagtgtt gactggatcc ctctatactg aaacaaatga
      721 acagggatta acgattccaa gcagtttact aaaaaattgg aatgaacaga caggaaaaaa
      781 tttgacaact aatgatctta ttggcaaatc agtctcagcc agcattgtag aaagtgctgc
      841 cgaaactagt aagattgctc aatttcaaac gaagattgta cgtgtaatca atgatgaaga
      901 tgacatggag gacagcaaca gtttcatgct gtctcatcaa attgaaacga ttttgaaaga
      961 ggctggattt acgaaagctg tatcttattt tatcttggaa ctcaaagatc catcacagac
     1021 aaaagtagta acagaagaat tacagaaaaa taagaagtat actgtgtttt ctcaacagag
     1081 agttcttgat attgtgatta cctttattcg tgttattcag ggattattga ttgtgctttc
     1141 atcacaagct attgtggtag cagcggttat gattggtatc attatttaca tcaatatcat
     1201 gcaacgttcc aaggaaatag gtgtcatgaa agcagttggt tatcagaatc gtggtgtcaa
     1261 aggaattttt atttacgagg ctatctggat tgtaggcatc gccttgctgc tggcattttt
     1321 ggttgcacaa ggggtgggaa gtttggcgaa tgcgattgta agtcactttt acccatccat
     1381 cactaaggtt tttgaattaa atcttttatc tgttttagga actctagttt tcgctctatt
     1441 acttggttat gtctcagcct acttcccggc gcgtaagatt agtaaaatgg atcctgtaga
     1501 atcgttacgc tatgaataat aagggattcc ttgatttaca gtcttaaaaa gaaactcaca
     1561 tagaaaaaca atggccatac ttgcaattca actcaaatag ttgtataata ggtttgttga
     1621 aaggtgattt gtagtgattc aagttactct tttcacaata aaaatttcat gattttcata
     1681 aggaggaaat cactaatggt agttaaagtt ggtattaacg gtttcggacg tatcggtcgt
     1741 cttgctttcc gtcgtatcca aaacgtagaa ggtgttgaag ttacacgcat caacgacctt
     1801 acagatccag ttatgcttgc acacttgttg aaatacgaca caactcaagg tcgtttcgac
     1861 ggtactgttg aagttaaaga aggtggattc gaagttaacg gtaaattcgt taaagtttct
     1921 gctgaacgtg atccagagca aatcgactgg gctactgacg gtgtagaaat cgttcttgaa
     1981 gctactggtt tctttgctaa gaaagaagca gctgaaaaac accttaaagg tggagctaaa
     2041 aaagttgtta tcactgctcc tggtggaaac gacgttaaaa cagttgtatt caacactaac
     2101 cacgacgttc ttgacggtac tgaaacagtt atctcaggtg cttcatgtac tacaaactgc
     2161 ttggctccaa tggctaaagc tcttcaagat aactttggtg ttgttgaagg attgatgact
     2221 actatccacg cttacactgg tgaccaaatg atccttgacg gaccacaccg tggtggtgac
     2281 cttcgccgtg ctcgcgctgg tgctgcaaac atcgttccta actcaactgg tgctgctaaa
     2341 gctatcggtc ttgtaatccc agaattgaac ggtaaacttg acggatctgc acaacgcgtt
     2401 ccaactccaa ctggatcagt tactgaattg gtagcagttc ttgaaaagaa cgttactgtt
     2461 gatgaagtga acgcagctat gaaagcagct tcaaacgaat catacggtta cacagaagat
     2521 ccaatcgtat cttcagatat cgtaggtatg tcttacggtt cattgtttga cgcaactcaa
     2581 actaaagttc ttgacgttga cggtaaacaa ttggttaaag ttgtatcatg gtacgacaac
     2641 gaaatgtcat acactgcaca acttgttcgt actcttgaat acttcgcaaa aattgctaaa
     2701 taattcttga gttgatagaa agcaaggctt tgtggtcttg ctttttatat ggaaaaatgg
     2761 atgacacgat catccattct tttttaattc tttttcaaat gtatttgaaa gggtagtgaa
     2821 agttagcttc tctaaagtaa gtgggtgggt aaaggaaagt cggaaggcat gaagcataag
     2881 ccgacttgtc tttgatttac tattatagag agggtcgccc aggataggaa gattatgatg
     2941 cgaaaggtgc acacgaatct gatgggttcg ccctgtcttt agcttgcaac gagccaagga
     3001 agtcttgttt gagaattgct ttaacctgct tacatgcgtt tcagcatatt gcccattttt
     3061 tgcatcaact attctttttc tacgatcatg gcgatcacgt ccaattttgt ctctgaaaac
     3121 aagttctttt ctgttgatat ttccatcaac tagagcccaa tattctctag aaatctcttt
     3181 tttctccaat aagcgattga gaatgggcag gataaaagga tttttggcaa agagaactaa
     3241 gccactggtt tccatgtcca gacgatgaac gacatagcag gtttggccaa cataggtact
     3301 gacatggtta agaagggcaa tttcgtttgg ttgattacca tgcgttttca tcccctctgg
     3361 tttgtttaca ataatcaagt gttgatcttg ataaacttcc tgcactaagt ctgggttgcc
     3421 ccaagggatc gtcttttggg aataatcttc ctcgtcaaaa gtcaactggc aaacatctcc
     3481 aggatttacg atttcgttcc agtggacttc ttcttgattt atcaaaatat gtttcttgat
     3541 tctcaaaaaa tgacggattt ttctagggat gaggagttgt tcctcaagta attgctttac
     3601 cgtcatttga ggtagagagg cgggtaatgt aaatgtgaat tgcatacaga tattgtaaca
     3661 aaaaaagccc tatttggata ggaaatagct aaattcttgt cttcctatga tgaagatgat
     3721 aaaataaacg catgaaatta gataaattat ttgagaaatt tctttctctt tttaaaaaag
     3781 aaacaagtga actagaggac tctgattcta ctatcttacg tcgctctcgt agtgatcgaa
     3841 aaaaattagc ccaagtaggt ccgattcgaa aattctggcg tcgttatcat ctaacaaaga
     3901 ttatccttat actaggtttg agtgcaggct tgctagttgg aatctatttg tttgctgtag
     3961 ccaagtcaac caatgtcaat gatttgcaaa atgccttgaa aactcgaact cttatttttg
     4021 accgtgaaga aaaagaggct ggtgccttgt ctggtcaaaa gggaacctat gttgagctga
     4081 ctgacatcag taaaaacttg cagaatgctg ttattgcgac agaagaccgt tctttctata
     4141 aaaatgacgg gattaactat ggccgtttct tcttggctat tgtcactgct ggccgttcag
     4201 gtggtggctc taccattacc caacagctgg ctaaaaacgc ctatttatcg caggatcaaa
     4261 ctgttgagag aaaagcgaaa gaatttttcc ttgccttaga attaagcaaa aaatatagta
     4321 aggagcaaat tctaaccatg taccttaaca acgcttattt tggaaatggt gtgtggggtg
     4381 tagaagatgc gagtaagaaa tactttggag tttctgcatc agaagtgagt ctggatcaag
     4441 ctgcgactct ggcagggatg ctcaaggggc cggaactgta taatcccttg aattccgtag
     4501 aagattctac taatcggcgc gatactgtct tgcagaatat ggttgcagca ggatatattg
     4561 ataaaaacca agaaaccgaa gctgctgaag ttgatatggc ttcgcaattg cacgataagt
     4621 atgaaggaaa aatctcagat taccgttacc cctcttattt tgatgcggtg gttaatgaag
     4681 ctgtttccaa gtataatcta acagaggaag agattgtcaa taatggctac cgcatttaca
     4741 cagagctgga ccaaaactac caagcaaata tgcaggttgt ttatgaaaac acatcgctat
     4801 ttccgagggc agaggatgga acgtttgctc aatcaggaag tgtagctctc gaaccgaaaa
     4861 cagggggagt tcgtggagtt gtcggtcaag ttgctgacaa tgataaaact ggattccgga
     4921 atttcaacta tgcaacccaa tcaaagcgta gtcctggttc tacaattaag cctttagttg
     4981 tttatacgcc agcagttgaa gcaggctggg ctttgaataa gcagttggat aaccatacca
     5041 tgcagtatga cagctataag gttgataact atgcagggat caaaacgagt cgagaagttc
     5101 ctatgtatca agccttggca gaatcgctta atctacctgc tgttgccact gttaatgatt
     5161 tgggtgtcga caaggctttt gaggcaggcg aaaaattcgg actcaacatg gaaaaggtcg
     5221 accgtgttct tggtgtcgcc ttgggaagcg gtgttgaaac caaccctctt caaatggctc
     5281 aagcatacgc cgcctttgca aatgaaggtt taatgcctga agctcatttt attagtagaa
     5341 ttgaaaatgc tagtggacaa gttattgcga gtcataaaaa ttcacaaaaa cgggtgattg
     5401 ataagtctgt agctgacaag atgaccagta tgatgttggg gactttcacc aacggtaccg
     5461 gtattagttc atcgcctgca gactatgtca tggcagggaa aactggaaca actgaagcag
     5521 ttttcaatcc ggagtacaca agtgaccagt gggtaattgg ttatactccg gatgtagtga
     5581 ttagccactg gcttggcttt ccgaccactg atgaaaacca ttatctagct ggctctactt
     5641 caaacggtgc agctcatgtc tttagaaaca ttgccaatac cattttacct tatacgccag
     5701 gaagtacctt tacggttgaa aatgcttata agcaaaatgg aattgcacca gccaatacaa
     5761 aaagacaagt acaaaccaat gataatagcc agacagatga taatttgtct gatattcgag
     5821 ggcgtgcgca aagtctagta gatgaggcta gccgggctat ctcagatgcg aagattaagg
     5881 aaaaggctca aacaatatgg gattcgatag tcaatctatt tcgctaagat gcttgtcaaa
     5941 gcctagcttt cttgttataa tggataagat ggaggcgtta tggcactaaa aaaagcaagc
     6001 ctagcttgtg cggtttgtgg ttcgagaaac tattcaatca agatcagcgg aaaccccaag
     6061 cctacacgac tagaagtaaa taaattttgt aagcattgtg gcaagtacac tacacacaga
     6121 gaaacgagat aggagagagc gatgcgtttt attggagata tttttagact tcttaaagac
     6181 acaacatggc caactcgcaa ggaaagctgg agagattttc gttctatcat ggaatacaca
     6241 gctttctttg tagtaattat ttacattttt gaccagttga ttgtttcagg tttgattcga
     6301 tttattaaca ttttttagaa gattagtgga gttaattaca ctagaaatct tctatttatg
     6361 aaaggaaata tcatggatag ttttgataaa gggtggtttg ttttacaaac ttattctggt
     6421 tatgaaaata aggtgaaaga aaatctatta caacgtgcac aaacctacaa tatgttggat
     6481 aatattctac gcgttgaaat tccaacacaa acagtgcaag ttgaaaaaaa tggaaagaga
     6541 aaagaagtag aagaaaatcg ctttccaggt tatgttcttg tagaaatggt catgacagat
     6601 gaagcttggt ttgttgttcg aaacacacca aatgttacag gatttgtcgg atcacacggg
     6661 aacagatcaa aaccaactcc attattggaa caagaaattc gcgacatttt ggtatctatg
     6721 ggacaaactg ttcaagaatt tgatttcgat gttgagattg gtcaaactgt acgtattatt
     6781 gatggtgctt ttgcagacta cactggtaag attacagaaa ttgataataa caaagtgaaa
     6841 atgattatct ctatgtttgg taatgacaca gttgcagaag taaatctaaa ccaaatcgca
     6901 gaattataac cctgagagag gctggaccct ctcttttttg tgcagtttag gagctaaagg
     6961 gaacagaatg gagaaaatgg aacaaatgtg ttttctaatc tgttagactg tatctagaaa
     7021 ggggaaaatt atgattaaag aattgtatga agaagtccaa gggactgttt ataagtgtag
     7081 aaatgaatat taccttcatt tatgggaatt gtcggattgg gaccaagaag gcatgctctg
     7141 cttacatgaa ttgattagta gagaagaagg actgg
//
LOCUS       DAVLXH010000080         7036 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00028199
            SAMN33607166-rid17955573.denovo.081, whole genome shotgun sequence.
ACCESSION   DAVLXH010000080 DAVLXH010000000
VERSION     DAVLXH010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607166
            Sequence Read Archive: SRR23725544
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7036)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7036)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721421.1
            Genome Coverage       :: 115x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:42:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,210
            CDSs (total)                      :: 2,161
            Genes (coding)                    :: 2,023
            CDSs (with protein)               :: 2,023
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 73 of 138
            Pseudo Genes (incomplete)         :: 60 of 138
            Pseudo Genes (internal stop)      :: 40 of 138
            Pseudo Genes (multiple problems)  :: 31 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7036
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607166-rid17955573.denovo.081"
                     /strain="AUSMDU00028199"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1349"
     gene            complement(<1..401)
                     /locus_tag="VYO11_002006"
     CDS             complement(<1..401)
                     /locus_tag="VYO11_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001856457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV1596501.1"
                     /translation="MEQLHFITKLLDIKDPNIKILDIINMDTHKEIIAKLDYEAPSCP
                     DCGSLMKKYDFQKPSKIPYLETTGMPSRILLRKRRFKCYHSSKMMVAETPLVKKNHQI
                     PRIINQKIAQKLIEKISMTDIAHQLAISTSTV"
     gene            629..1165
                     /locus_tag="VYO11_002007"
     CDS             629..1165
                     /locus_tag="VYO11_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HEV1596502.1"
                     /translation="MSYFKKYKFDKSQFKLGMRTFKTGIAVFLVLLIFGFFGFFGWKG
                     LQIGALTAVFSLRESFDESVHFGTSRILGNSIGGLYALVFFLLNTFFHEAFWVTLVVV
                     PICTMLTIMTNVAMNNKAGVIGGVAAMLIITLSIPSGETISYVFVRVSETFMGVFVAI
                     IVNYDIDRIRLFLEKKEK"
     gene            1242..1598
                     /gene="glnR"
                     /locus_tag="VYO11_002008"
     CDS             1242..1598
                     /gene="glnR"
                     /locus_tag="VYO11_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000659547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor GlnR"
                     /protein_id="HEV1596503.1"
                     /translation="MKEKEFRRNMAVFPIGSVMKLTDLSARQIRYYEDQELIKPDRNE
                     GNRRMYSLNDMDRLLEIKDYISEGYNIAAIKKKYAEREAKSKKAVSQTEVRRALHNEL
                     LQQGRFASVQSPFGRG"
     gene            1635..2981
                     /gene="glnA"
                     /locus_tag="VYO11_002009"
     CDS             1635..2981
                     /gene="glnA"
                     /locus_tag="VYO11_002009"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HEV1596504.1"
                     /translation="MPITAADIRREVKEKNVTFIRLMFSDILGTMKNVEIPATDEQLD
                     KVLSNKVMFDGSSIEGFVRINESDMYLYPDLDTWTVFPWGDENGSVAGLICDVYTTEG
                     EPFAGDPRGNLKRALRHMEEVGFKSFNLGPEPEFFLFKLDENGDPTLEVNDKGGYFDL
                     APTDLADNTRREIVNVLTKMGFEVEASHHEVAVGQHEIDFKYDEVLRACDKIQIFKLV
                     VKTIARKHGLYATFMAKPKFGIAGSGMHCNMSLFDAEGNNAFFDPNDPKGMQLSETAY
                     HFLGGLIKHAYNYTAIMNPTVNSYKRLVPGYEAPVYIAWAGRNRSPLVRVPASRGMGT
                     RLELRSVDPMANPYVAMAVLLEVGLYGIENKIEAPAPIEENIYIMTAEERKEAGITDL
                     PSTLHNALKALTEDEVVKAALGDHIYTSFLEAKRIEWASYATFVSQWEIDNYLDLY"
     gene            complement(3077..3196)
                     /locus_tag="VYO11_002010"
     CDS             complement(3077..3196)
                     /locus_tag="VYO11_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine synthetase"
                     /protein_id="HEV1596505.1"
                     /translation="MPDIVFEIEFFHSDSLIFFYTSDDKSNSQKSQEDFSKNK"
     gene            3741..5060
                     /locus_tag="VYO11_002011"
     CDS             3741..5060
                     /locus_tag="VYO11_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEV1596506.1"
                     /translation="MPDTWEWVRFSTLVEIVRGGSPRPIKDYLTSEVDGINWIKIGDT
                     EKGEKYINNVKEKIKKSGLNKTRFVKKGTFLLTNSMSFGRPYILNVDGAIHDGWLAIS
                     NYENSLNKDYLFYILSSNVVYSQFLSLISGAVVKNLNSDKVASILIPLPPLSEQQRIV
                     EAIESALEKVDEYAESYNRLEQLDKEFPDKLKKSILQYAMQGKLVEQDPNDESVEVLL
                     EKIRAEKQKLFEEGKIKKKDLDISIVSQGDDNSYYEEVPCEIPESWEWVRLNDITSYI
                     QRGKSPKYSNIPIYPVIAQKCNQWSGFSIDLARFIDPETVHSYQKERLLRDGDLMWNS
                     TGLGTLGRLAIYHENKNPYGWAVADSHVTVIRVLSGVINCHFIYNFLSSPIVQSVIEE
                     KASGSTKQKELLTKTIKEYLIPLPPLPEQSRIVDKIEQFFAHIDALI"
     gene            5117..5914
                     /gene="psrA"
                     /locus_tag="VYO11_002012"
     CDS             5117..5914
                     /gene="psrA"
                     /locus_tag="VYO11_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type DNA invertase PsrA"
                     /protein_id="HEV1596507.1"
                     /translation="MKDFELHLKKAGLAENTVRSYLYGVRFFLENYELKMEDLFEYKG
                     YLLDNFKPKTVNLRLQGVNKYLAFIGHDDLKLKFVKVQQKPFLEDVISHADYLFLKRS
                     LKKDGILKWHFVVWFLGATGARVSELIKLKVEHVEIGYFDIYSKGGKIRRLYIPKKLR
                     NSCLSWLESENRRSGYLFLNKFNEPITARGVAQQLKNYADKYKMNPKVIYPHSFRHLF
                     AKNFLAKYNDIALLADLMGHESIETTRIYLRKTATEQQNIVDKIVNW"
     gene            5925..6530
                     /locus_tag="VYO11_002013"
     CDS             5925..6530
                     /locus_tag="VYO11_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012291636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEV1596508.1"
                     /translation="MVKLTTCYFCDYGSYYGNIPMNWVVIKIKDIFSINTGLSYKKGD
                     LSINNKGIRIIRGGNIKPLEFSLLDNDYYIDTQFISSEQVYLKHNQLITPVSTSLEHI
                     GKFARIDKDYDGVVAGGFIFQLTPFESSEIISKFLLFNLSSPLFYKQLKAITKLSGQA
                     LYNIPKTTLSELLIPLAPFEEQELITQKVEKLFEKVNQLWK"
     gene            complement(6478..>7036)
                     /locus_tag="VYO11_002014"
     CDS             complement(6478..>7036)
                     /locus_tag="VYO11_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEV1596509.1"
                     /translation="NKDETTSYPIYEIPEAWRYIKFASLVNFRIGKTPPRSEATFWGT
                     EIPWVSISDMPISGYVTNTRESISKLALKSKKIDISPKGTLLMSFKLSIGKVAILDIP
                     ATHNEAIISIFPYANKENIIRDYLMIFLPLISTLGDSKDAIKGKTLNSTSISELLIPI
                     SNHEEMKRIISKVDLLFQKVSQLFE"
BASE COUNT         2291 a         1109 c         1337 g         2299 t
ORIGIN      
        1 acagttgaag ttgaaatggc cagctgatgg gcaatatcag tcatagaaat tttttcaatt
       61 aacttttgag caattttttg gttgatgata cgagggattt ggtgattttt ctttaccagg
      121 ggagtctcag caaccatcat ttttgaagag tgatagcact tgaaacggcg ttttctaagg
      181 agaattctag aaggcatacc agttgtttcg aggtaaggga tcttagacgg tttttgaaag
      241 tcatatttct tcattagact tccacaatca gggcaagatg gagcctcata atccagctta
      301 gcgataattt ctttgtgggt atccatattg atgatatcta gaatcttgat gtttgggtct
      361 ttaatatcga gcagttttgt gataaaatgt aattgttcca tatgaatctt tctaatgatg
      421 gttttgtcgc ttttcattat aggtcatatg ggactttttt tctacaataa aataggctcc
      481 ataatatcta tagtggattt acccactaca aatattatag agcctgaaag ttcctctttt
      541 cttttgctta aaataaaaac gcttcctctc aactattact cataaaaatc accgatttat
      601 gataaaatgg aaatagaaag ttgagattat gagttatttt aaaaaatata aattcgataa
      661 atcccagttc aaacttggta tgcgaacctt taaaacaggt attgctgttt ttctagttct
      721 cttgattttt ggcttttttg gcttttttgg ctggaaaggt cttcaaattg gtgctttgac
      781 agccgttttt agcctgaggg agagttttga tgagagtgtt cattttggga cttcgcgtat
      841 tctaggaaat agtatcggtg gactctatgc cttggtcttc ttcttattaa ataccttttt
      901 ccatgaagcc ttttgggtga ccttggtagt tgttccaatc tgcaccatgt taaccattat
      961 gacaaatgta gccatgaata acaaagcagg ggttattggt ggtgtagcag ctatgttaat
     1021 cattacccta tcaattccaa gtggtgagac aatttcgtac gtgtttgtac gtgtatcaga
     1081 aacgtttatg ggagtttttg tcgcaattat cgtaaattac gatattgatc gtattcgtct
     1141 ctttttagag aaaaaagaaa aataatgtta cattttataa cattatcaat tgacgtttgt
     1201 ctttttttag actataatag acagaaagaa ggaaattgta aatgaaggaa aaagaatttc
     1261 gccgaaatat ggctgttttt cctatcggca gtgttatgaa gttgaccgat ctatcggcgc
     1321 gtcagattcg ttattatgaa gatcaagagt tgatcaagcc cgatcgaaac gaaggaaatc
     1381 gtcgcatgta ttccttgaat gacatggatc gtctgcttga aatcaaagat tatatctctg
     1441 aaggttataa tatcgctgcc attaagaaaa aatatgctga acgtgaagcg aaatccaaga
     1501 aagcggttag tcagactgaa gtacgtcgtg cacttcacaa tgaactcctc caacaggggc
     1561 gttttgcttc agtacagtca ccttttggtc gcggttaggc aaccgcaagt agtcatagat
     1621 taaggagaaa acttatgcca atcacagctg cagatattcg tcgtgaagtc aaggaaaaaa
     1681 atgttacctt tattcgtctt atgttctcag atattttggg aaccatgaaa aacgtcgaaa
     1741 ttcctgctac agatgaacag ttagataagg tcttgtcgaa caaggttatg tttgatggat
     1801 cttctattga aggttttgta cgtatcaatg agtcggatat gtacttgtac ccggacttgg
     1861 atacatggac agtcttccct tggggagatg aaaatggaag tgttgcaggt ctgatctgtg
     1921 atgtctatac aacagaaggt gaaccatttg cgggtgaccc tcgtggtaat ttgaaacgag
     1981 ctcttcgtca catggaagaa gttggattca aatccttcaa ccttggtcca gagccagaat
     2041 tcttcctatt taagttggat gaaaatgggg acccaacact tgaagtgaat gacaagggtg
     2101 gctactttga tttggcacct actgaccttg cggacaacac acgtcgtgag attgtgaatg
     2161 tcttgaccaa aatgggattt gaagtagaag cgagtcacca cgaggttgcg gttggacagc
     2221 atgagattga ctttaagtac gatgaagttc tccgtgcttg tgataagatt caaatcttta
     2281 agcttgttgt taaaaccatt gctcgcaaac acggacttta cgcaacattt atggcgaagc
     2341 caaaatttgg tattgctgga tcaggtatgc actgtaatat gtccttgttt gatgcagaag
     2401 gaaataacgc cttctttgat ccaaatgatc caaaaggaat gcagttgtca gaaacagctt
     2461 accatttcct aggcggtttg atcaagcatg cttacaacta tactgccatc atgaacccaa
     2521 cagttaactc atacaaacgt ttggttccag gttatgaagc gcctgtttac attgcttggg
     2581 ctggtcgtaa ccgttcgcca cttgtgcgcg tacctgcttc acgtggtatg ggaactcgtc
     2641 ttgagttgcg ttcagtggat ccaatggcga acccttacgt tgctatggct gttcttttgg
     2701 aagttggttt gtatggtatt gaaaataaaa tcgaagcacc agctcctatc gaagaaaata
     2761 tctacatcat gacagcagaa gagcgcaagg aagctggtat tacagacctt ccatcaactc
     2821 ttcacaacgc tttgaaagct ttgacagaag atgaagtggt taaagctgct ctcggagatc
     2881 acatctatac tagcttcctt gaagccaaac gaatcgaatg ggcaagttat gcaaccttcg
     2941 tttcacaatg ggaaattgat aattatttag acctttacta atactaatat agaagaaaga
     3001 ttgcctgtgg gtaaacagtc acacagcagt ctaagccatc aaatacctat aacccttaaa
     3061 atagcgattt cggtcgctat ttatttttcg aaaaatcctc ttgactcttt tgcgaattag
     3121 atttatcatc agacgtgtag aagaaaatta aggagtcact atggaaaaat tcaatttcaa
     3181 aaacaatatc gggcaagaaa acaagttact tcaaatcgaa atctacaagt ttactaactt
     3241 ttgcaagctt caaaattaca catctgtaaa tattttttcg aaagatatat ttgaagccat
     3301 agtaaattga gactagaata gtacactaca tctgctaaaa atttctagaa actaatttaa
     3361 ctttcctaat cgatttgttt acatcttatt tcaatctact atattatctc aataaatgat
     3421 gatggcgact gttttgtttg tgcttgtcga tttttgaatc ctgatcgagc ggaagaatat
     3481 ttctgccgag gttgtcaagg ggaaaatcct gaagatattg aattttatga tgaacaatta
     3541 caggcagaaa aggtggaggc tttgaatatt cgattggaag taaaaaattg aattatctac
     3601 aatctcatca acaataaacc tatttcaacc ccattatcta taggcgtatt tttacgcctt
     3661 tttatatact tgaagcacat aagaaacatt atgggaagtt tgctgatgga agcactcaag
     3721 aaattgatgt tccttatgat attcctgata cttgggagtg ggtgaggttt tctacattgg
     3781 ttgaaattgt cagaggtggc tctccacgac caatcaaaga ttatcttact tctgaagtag
     3841 atggaataaa ttggataaaa ataggtgata ctgaaaaggg tgaaaagtat ataaataatg
     3901 ttaaagaaaa aatcaaaaaa tcagggctta acaaaactag atttgtaaaa aaaggtacat
     3961 ttttgttaac taattctatg agttttggta gaccttatat tttgaatgtt gatggtgcaa
     4021 tacacgatgg atggttggct atttcgaact atgaaaactc attaaataaa gattacctat
     4081 tctatattct ttcatcaaat gtagtttatt ctcaatttct atctctaatt agtggagctg
     4141 ttgtgaaaaa cttgaatagt gataaagttg cttctattct tatccctctc cctccactat
     4201 ccgaacaaca acgaatagta gaagcaatcg aatcagcttt agaaaaagta gatgaatatg
     4261 ctgaaagtta taatagacta gaacagctag ataaagaatt tccagataaa ctaaaaaaat
     4321 ctattcttca atatgctatg caaggaaaat tagttgaaca agacccaaat gatgaatcag
     4381 tcgaagtttt acttgaaaaa atacgagcag aaaaacaaaa actctttgaa gaaggcaaga
     4441 ttaaaaagaa agatttggac atttctattg tttcccaagg agatgataac tcttattatg
     4501 aggaagtacc ttgtgaaata ccagaaagtt gggaatgggt gaggttaaac gatataacct
     4561 cctacattca aagagggaag tctccaaaat attcaaatat tcctatatac cctgtgattg
     4621 ctcagaaatg taatcaatgg tctggctttt ctattgactt agcaagattt attgatcccg
     4681 aaacagttca tagttaccag aaagaaagat tactaagaga tggtgattta atgtggaatt
     4741 caacaggtct aggtacgtta ggacgattag ctatttacca tgaaaataaa aatccttatg
     4801 gctgggctgt tgcagatagc catgttacag ttataagagt cttatcggga gttattaatt
     4861 gccatttcat ctataatttt ctttcctctc ctattgttca gtcagttatt gaagaaaaag
     4921 cgtcgggtag tacaaaacaa aaagaattat taacgaaaac tataaaagaa tatttaatcc
     4981 ccctcccacc ccttcctgaa caatccagaa tcgttgataa aatcgaacaa tttttcgccc
     5041 atattgacgc actaatttag tataatagtt ttacgtgcgg tggaatttct atcaaacata
     5101 agataggagt tttacgttga aagattttga attacatttg aagaaagctg gtttagctga
     5161 aaatactgtg cgttcgtacc tttatggtgt tcgatttttc ttggagaatt acgaactcaa
     5221 aatggaagat ttatttgaat acaaaggata tttattagac aattttaaac ctaaaactgt
     5281 caatttgcga ctacaaggag taaataaata tctggctttt attggtcatg atgatttgaa
     5341 attaaaattt gtcaaagtac agcaaaaacc gtttttagaa gatgtcatta gccatgctga
     5401 ttaccttttt cttaaacgta gtttgaaaaa agatggtatt ttaaaatggc attttgtcgt
     5461 ttggttttta ggtgcaactg gggctcgtgt aagtgaactt attaaactaa aagtagagca
     5521 tgtagaaatc ggttattttg acatttactc aaaaggtggt aaaattcgta gactgtacat
     5581 tcctaaaaaa ttaagaaata gttgtcttag ttggttagaa tcagaaaatc gccgaagtgg
     5641 ttatttattt ttgaataaat ttaacgaacc aattacagca agaggagttg ctcaacagtt
     5701 aaaaaattat gctgataaat acaaaatgaa tcctaaagta atttaccctc attcttttag
     5761 gcatttattt gctaagaatt ttttagcgaa gtataatgat attgccttgc ttgcagattt
     5821 gatgggacac gaaagtatag aaactactcg aatttatcta aggaaaacag ctactgaaca
     5881 acaaaatatt gtagataaaa ttgttaattg gtaaaaaata acaggtggtc aaactgacta
     5941 cctgctattt ttgtgattat ggctcttatt atgggaatat acctatgaat tgggttgtta
     6001 taaaaataaa agatattttt tcaataaata caggtctttc ttacaagaag ggcgatttaa
     6061 gcattaataa taaaggtatt agaattatac gtggtggtaa tattaagcct ttagaatttt
     6121 ctctgttgga taatgattac tacattgata cacaattcat ctcctctgag caagtttatt
     6181 taaaacataa tcagctaata acacctgtat caacctcttt agaacatatt ggaaagtttg
     6241 caagaatcga taaagactat gatggtgttg tggctggtgg attcattttc caattaacac
     6301 cattcgaaag ttcagagatt atttcaaaat ttctattatt taacttgtcc tctccgttat
     6361 tttataaaca attgaaagca ataactaaac tatcaggtca agctttatat aatattccta
     6421 aaactacact aagcgagcta ttaattccgt tagctccttt tgaggaacag gaacttatta
     6481 ctcaaaaagt tgagaaactt tttgaaaaag taaatcaact ttggaaatga ttcttttcat
     6541 ctcttcatga ttagaaatag ggattaataa ttcggagata ctggtactat ttaatgtttt
     6601 ccctttgata gcatcttttg aatcacctaa agtagagata agtggcaaaa atatcattaa
     6661 gtaatctctg ataatatttt ctttattagc ataggggaat atcgatataa tggcttcatt
     6721 atgagtggca ggaatatcca atatggcaac ttttccaata gataatttaa agctcattaa
     6781 taaagttcct ttaggtgaaa tgtctatttt ctttgatttt aatgctaatt tagaaataga
     6841 ttctctcgta ttagttacat aaccagatat aggcatatct gatatagata cccagggtat
     6901 ttcagttccc caaaaagtag cttcactgcg tggaggagtt tttcctattc tgaagttaac
     6961 taggctagca aatttaatat atctccatgc ttctgggatt tcatatatag gataagaggt
     7021 tgtttcgtct ttattc
//
LOCUS       DAVLXH010000081         6869 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00028199
            SAMN33607166-rid17955573.denovo.082, whole genome shotgun sequence.
ACCESSION   DAVLXH010000081 DAVLXH010000000
VERSION     DAVLXH010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607166
            Sequence Read Archive: SRR23725544
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6869)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6869)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721421.1
            Genome Coverage       :: 115x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:42:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,210
            CDSs (total)                      :: 2,161
            Genes (coding)                    :: 2,023
            CDSs (with protein)               :: 2,023
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 73 of 138
            Pseudo Genes (incomplete)         :: 60 of 138
            Pseudo Genes (internal stop)      :: 40 of 138
            Pseudo Genes (multiple problems)  :: 31 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6869
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607166-rid17955573.denovo.082"
                     /strain="AUSMDU00028199"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1349"
     gene            43..3393
                     /locus_tag="VYO11_002015"
     CDS             43..3393
                     /locus_tag="VYO11_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000526318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEV1596510.1"
                     /translation="MGNFSFLLKNDEYESFSKPCIEAENMIATSTVATAFMARRALEQ
                     AVHWIYSHDSYLEAPYRATLSSLVWDDDFRDIVDSELHKQIVLLIRWGNHAAHGGEIK
                     EREAILALHHLYQFVNFIDYCYSNEFVERYFDEKCLPLSANIKYRETPQSMIKLQDSL
                     PELPDFHEQMAAQSVEVQETYTEKRETAAQRQDVPFHIEQLSEAETRKLFIDIDLRLA
                     GWIFEENCRVEIAVDGLKHGSGIGYCDYVLYGKNGKILAIVEAKKASVNPEVGEVQVK
                     EYAEALEKHIGYQPICFITNGLKHYILDGPNRRQIAGFYSQEELQLVMDRRHLQKPLE
                     DISSKIRDDISGRHYQKHAIASVCEAFSNHRRQALLVMATGAGKTRTAVSLVDILSRH
                     NWVKNVLFLADRTSLVKQAYDSFRKLLPDLSVCNFLEDKEGAQSSRMVFSTYPTMIGA
                     ISGQEEVNQRPFTVGHFDLIIIDESHRSIYQKYKSIFDYFDARIVGLTATPRQDLDKN
                     TYGFFNLENGVPTYAYDLEEAVKDGYLVAYHSIETKLKLPTDGLHYDDLSEEEKEHFD
                     SKFEDDSCEKDIDGSVFNSFIFNKSTVEIVLNELMTRGIQTASGDEIGKTIIFAKNHD
                     HAEYIRGIFNNRYPEKGSDYAQVIDYSIKHYQTLIDDFKIKEKYPQIAISVDMLDTGI
                     DVPEVVNLVFFKKVRSKTKFWQMIGRGTRLCKDLFGPEQDKENFLVFDYGDNFDYFRA
                     DPRDGEGRHIVSLTQRLFNIKVDLIRELQGLQYQEDQFARAYRQQLVSELQGRIESLN
                     ELDFRVRMVLDTVYSYRKLESWQNLTAVTSETIQKNLSPLLFDEDKEDEMARRFDLWL
                     LHIQLGQLTAKSSTVHISQVMKTARALSAIGNIPQVFEQAEIIRKVQEPEFWKEVNLS
                     DLEKIRLAIRDLLQFLDKTDRKPYYVNFEDRILSTVHETTAFLQVNDLRSYNEKVEHY
                     LKTHLDEESISKLYHNKKLTSDDMLALEKLLWEKLGSKADYQSHYENKAIPRLVREII
                     GLDRESANRIFSKFLSDENLNARQISFVKLIVDYIVENGFLETKVLTQEPFKSYGSVQ
                     LLFQHQLPVLRNIVQIIELINNRAGEAA"
     gene            3664..3741
                     /locus_tag="VYO11_002016"
                     /pseudo
     CDS             3664..3741
                     /locus_tag="VYO11_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(3979..4449)
                     /locus_tag="VYO11_002017"
     CDS             complement(3979..4449)
                     /locus_tag="VYO11_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001043003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEV1596511.1"
                     /translation="MNKSEHRHQLIRALITKNKIHTQAELQALLAKNDIQVTQATLSR
                     DIKNMNLSKVREEDSAYYVLNNGSISKWEKRLELYMEDALVWMRPVQHQVLLKTLPGL
                     AQSFGSIIDTLSFPDAIATLCGNDVCLIICEDADTAQKCFEELKKFAPPFFFEE"
     gene            complement(4466..6739)
                     /locus_tag="VYO11_002018"
     CDS             complement(4466..6739)
                     /locus_tag="VYO11_002018"
                     /EC_number="3.4.14.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Xaa-Pro dipeptidyl-peptidase"
                     /protein_id="HEV1596512.1"
                     /translation="MRFNQYSYINFPKENVLSELKKCGFDLQNTANHKDSLETFLRRF
                     FFTYQDTNYPLSILAADKKTDLLTFFQSEDELTADIFYTVAFQLLGFSYLVDFEDSDV
                     FRKETGFPIIYGDLIENLYQLLNTRTKKGNTLIDQLVSDGLIPEDNDYHYFNGKSLAT
                     FSNQDVIREVVYVESRVDTDQKGLSDLVKVSIIRPRFDGKIPAIMTASPYHQGTNDKA
                     SDKALYKMEGELEVKLPHKIELEKPQLNLVQPQGKAELIAEAEEKLTHINSSYTLNDY
                     FLPRGFANLYVSGVGTKDSTGFMTNGDYQQIEAYTNVIDWLNGRCRAFTDHTRQRQVK
                     ADWSNGKVATTGLSYLGTMSNGLATTGVDGLEVIIAEAGISSWYNYYRENGLVTSPGG
                     YPGEDFDSLAELTYSRNLLAGDYIRGNEAHQADLEKVKAQLDRKTGDYNQFWHDRNYL
                     LNAHKVKAEVVFTHGSQDWNVKPLHVYQMFHALPTHINKHLFFHNGAHVYMNNWQSID
                     FRESINALLTKKLLGQETDFQLPTVIWQDNTAPQTWLSLDNFGGQENCETFSLGQEEQ
                     AIQNQYPDKDFERYGKTYQTFNTELYQGKANQITINLPVTKDLHLNGRAQLNLRIKSS
                     TNKGLLSAQLLEFGQKKYLQPYPAILSARTIDNGRYHMLENLCELPFRPEAQRVVTKG
                     YLNLQNRNDLLLVEDITADEWMDVQFELQPTIYKLKEGDTLRLVLYTTDFEITIRDNT
                     DYHLTVDLAQSMLTLPC"
BASE COUNT         2103 a         1161 c         1489 g         2116 t
ORIGIN      
        1 tagtataata tagctaaact atttgtttaa agtgagaaaa aaatgggaaa ttttagcttt
       61 cttttaaaaa atgacgaata tgaatctttt tcaaaacctt gcattgaagc tgaaaatatg
      121 attgctacat caactgtggc tactgccttt atggcgcgtc gtgctttgga gcaggctgtc
      181 cattggatat atagtcacga ttcatattta gaagctccct atcgtgctac tctatcttct
      241 ttagtatggg atgatgattt tagggatatc gtagattctg aactccacaa gcagatagtt
      301 ctgttgattc ggtggggaaa ccatgctgct catggtggtg aaattaagga acgagaagcg
      361 attttagctt tacatcattt gtatcagttt gttaatttta tcgattattg ttacagcaat
      421 gaatttgtgg agcgttattt tgatgagaag tgcttaccac tttcagcaaa catcaaatac
      481 cgagaaactc cacaatctat gataaagtta caagacagtt taccagaact gcctgatttt
      541 catgaacaga tggctgctca gtccgtagaa gttcaagaga cttatactga aaaacgtgag
      601 actgcagcgc aacggcaaga tgtgcctttc catattgaac aattatctga ggcagagaca
      661 agaaagctct ttattgatat cgatctccgt ttagcaggat ggatatttga agaaaactgt
      721 cgtgttgaga tagccgttga tggtctcaag cacggttcag gaattggtta ctgtgactac
      781 gtactttatg gtaaaaatgg gaaaatttta gcgattgtgg aggctaaaaa agcctctgtc
      841 aatccagaag taggggaagt acaggtcaaa gaatatgctg aagctttgga gaaacatatc
      901 ggctatcagc caatttgctt tattacaaat gggttgaagc actatatact tgatggtccg
      961 aaccgccgcc agattgcagg cttttactct caagaagaat tgcaattagt gatggataga
     1021 cgtcatcttc aaaaaccgct tgaggatatt tctagtaaaa ttagggacga tatttccggg
     1081 cgtcactacc aaaaacatgc cattgcaagc gtttgtgaag ctttctctaa tcatcgtaga
     1141 caggcacttt tggttatggc aactggggcg gggaaaactc gtacagcagt ttctctagtt
     1201 gatatcttat cacgtcataa ctgggtaaaa aacgttctct tcttagccga tagaacttcc
     1261 ttggttaagc aagcctatga ttcgtttaga aaattactcc cagatctttc cgtttgtaac
     1321 ttcttagaag ataaagaagg agctcaatca agtcgtatgg tcttttcaac ttatccgacc
     1381 atgattggag cgattagtgg tcaagaagaa gtaaatcaac gcccttttac tgttgggcat
     1441 tttgacctta tcataattga cgaatctcac cgttctattt atcagaaata caagtccatt
     1501 tttgattatt ttgatgcaag aattgtaggc ttaacagcta ctccgcgtca agatttagat
     1561 aaaaacacct atggattctt taatttggag aatggggttc caacatatgc atatgatttg
     1621 gaagaggctg ttaaagacgg atatttagta gcctatcatt ctatcgaaac caaactgaaa
     1681 ctacctacgg atggtctaca ttatgatgat ttgtccgaag aagaaaagga acattttgat
     1741 agcaaatttg aagacgatag ctgtgaaaaa gatattgatg ggagtgtgtt taattccttt
     1801 attttcaata aaagtacagt agaaattgtt ttaaatgaac tcatgacaag aggaattcag
     1861 acagcctcgg gtgatgaaat tggtaaaact attatttttg ctaaaaatca tgaccatgcg
     1921 gaatatatca gaggtatttt taacaaccgc tatcctgaaa aagggagcga ctatgctcag
     1981 gtgattgatt atagtattaa gcattatcag accttgattg atgattttaa aattaaggag
     2041 aagtatcctc aaattgcgat ttctgtcgat atgttagata caggtattga tgtaccagag
     2101 gttgttaatt tagtcttctt caagaaagta cgctctaaaa ctaagttttg gcagatgatt
     2161 ggtcgaggaa cccgtctatg taaagattta tttggacctg agcaggataa ggaaaacttc
     2221 ttggtatttg attatgggga taattttgat tattttcgtg cagatccaag agatggagag
     2281 ggtcgtcaca ttgtttcgtt gactcagcgt ttatttaata tcaaagtgga cttgattcga
     2341 gaacttcagg gactccaata ccaagaagat cagtttgcga gagcataccg tcagcagctt
     2401 gtctcggaac ttcaaggtcg tatagagagc ttaaatgagt tggacttcag ggttcgtatg
     2461 gttttagata cagtttatag ctataggaaa ttggaaagtt ggcagaatct aactgctgtt
     2521 acaagtgaaa ccattcaaaa aaatctctct ccgcttttat ttgatgaaga taaagaagat
     2581 gagatggcga ggagatttga tttgtggttg cttcatattc agttggggca actgacagct
     2641 aaatcttcca ctgttcatat ttcccaagtg atgaagacgg ctagagctct ttctgctatt
     2701 ggcaatatcc cgcaggtttt tgagcaggct gaaattatca ggaaagtaca ggagcctgaa
     2761 ttttggaaag aagttaactt gtctgatttg gaaaaaattc gtcttgctat tcgagattta
     2821 ttacagtttt tggataaaac agaccgtaaa ccctactatg ttaactttga agatcgtata
     2881 ctctccactg ttcacgagac cacagcattt ttgcaggtca acgatcttcg gtcttacaat
     2941 gaaaaagttg agcattattt gaaaactcat ctggatgagg agtccatttc taagctatac
     3001 cataataaaa agttgacatc tgatgatatg cttgcacttg aaaaattgct ctgggaaaaa
     3061 ttaggtagta aagcagacta ccaaagtcat tatgaaaata aggcaattcc gagattggtt
     3121 cgtgagatta ttggcttaga tagagagtct gccaatcgta ttttttctaa atttttgtcg
     3181 gatgagaatc ttaatgccag gcagatttca tttgtaaaat tgattgtaga ctacattgta
     3241 gaaaatggtt ttttagagac gaaagtgtta acgcaagagc cgtttaaatc ttatggttct
     3301 gttcaactac tcttccaaca ccaactacca gtacttcgta atattgttca aatcattgaa
     3361 cttatcaata atcgagctgg agaagcggct taaattctaa agtgattgcc atgctgagac
     3421 tcatttaaaa ttaaaaagag tagaaattta tgctatatat gagaagtttt attaggaaga
     3481 atgtcatcgt tttcctagag tacagtatca gttgttaagt ggttgataaa tttcaaagta
     3541 gatacttgta ccacgatgtt tgttgatcga gttattaaca aaagagctac tttgatttta
     3601 aagaaataga aaacaaaaag ccgagcaaga attcaattgc aggagaaaat gaaataatac
     3661 tcaatgaaaa tcaaagagca aactaggaaa ctagctgcag gctgctcaaa acactgtttt
     3721 gaggttgcag ataagactga cgaagtcagc tcaaaacatg gttttgaggt tgtagatgaa
     3781 actgacgaag tcagtaacca tacctacggc aaggcgacgt tgacgcggat tgaagagatt
     3841 ttcgaagagt ataaatcttc ctaggataaa gcaaaacgca tagtatcaag ggttttcaac
     3901 acttgatact atgcgttttc tgatgttaaa gactttctac cagttttttt aagcataatt
     3961 gttagttgta gtcatttatt attcttcaaa gaaaaatggt ggggcgaatt ttttcagttc
     4021 ttcaaagcac ttttgagcag tatctgcatc ttcacagatg ataagacaga catcattacc
     4081 acaaagggta gcgatagcgt cagggaagct caaagtatca atgatagaac caaaggattg
     4141 agccagtcca ggaagggttt ttagtaggac ttggtgttga actgggcgca tccagacaag
     4201 ggcgtcttcc atgtagagtt cgagacgttt ttcccatttt gagatggaac cattgttaag
     4261 aacataataa gcgctatctt cttcgcggac ttttgatagg ttcatatttt tgatgtcgcg
     4321 tgagagggtt gcctgggtta cttgaatgtc gttcttagca agaagggctt gcaactcagc
     4381 ctgtgtatga atcttgtttt ttgtgataag agcgcgtata agttggtggc ggtgttctga
     4441 tttattcata ataatgtaac tccttttagc aaggtaaggt aagcatggac tgagcgaggt
     4501 cgacagtcaa gtggtagtct gtattgtcac ggatggtgat ttcaaagtca gtagtataga
     4561 ggactaaacg gagagtgtct ccttctttta gcttgtaaat agttggctgc agttcaaatt
     4621 gaacatccat ccattcatct gcagtaatat cctctactaa cagtaaatca tttctatttt
     4681 gtaaattaag gtaacctttt gtcacgactc gttgtgcctc tggtctaaat ggcaattcac
     4741 agagattttc caacatgtga tagcgaccgt tgtcaatggt tctagcactt aaaatagctg
     4801 gataaggttg taggtatttc ttttgcccaa attctagcag ttgggcagat aagagcccct
     4861 tgtttgtact ggatttgata cgaagattga gctgagcgcg accgtttagg tggagatctt
     4921 tagtcacagg aaggttaata gtaatctgat tggctttccc ttgatagagc tctgtattga
     4981 aggtttggta tgtcttacca tagcgctcaa aatccttatc tgggtactgg ttttgaatag
     5041 cttgctcttc ttgaccaagt gagaaggttt cacagttttc ttgcccaccg aagttatcaa
     5101 gtgataacca agtctgtgga gctgtattgt cctgccagat aacagtagga agttgaaagt
     5161 ctgtttcctg tcctagtaat ttcttggtca ataaggcatt tatggactca cggaagtcaa
     5221 ttgattgcca attgttcatg taaacatggg caccattatg gaaaaagaga tgcttgttta
     5281 tatgagtagg aagagcatgg aacatctggt aaacatgaag tggtttgaca ttccaatcct
     5341 gagaaccatg agtaaagaca acctctgcct ttactttatg ggcattgagc agataattgc
     5401 ggtcatgcca aaactgattg tagtccccag tttttcggtc tagctgagct ttcacttttt
     5461 ctaagtcagc ttggtgagct tcattgccac ggatatagtc gccagctaag agattacgag
     5521 aataggttaa ctcagcaagg gagtcaaagt cctcacctgg ataaccacct gggctagtca
     5581 ccagaccgtt ttcacggtag tagttgtacc atgatgaaat tcctgcctcg gcaatgataa
     5641 cttctaaacc atcgactcct gtagtcgcaa gaccattgga catggtacct agataggaaa
     5701 gtcctgttgt agcaactttt ccgtttgacc aatcagcctt gacttgacgc tggcgcgtgt
     5761 gatcagtaaa ggcacggcaa cggccgttaa gccaatcgat gacatttgta taagcctcga
     5821 tttgctggta gtctccatta gtcatgaaac ctgtcgagtc tttggtacca acacctgaga
     5881 catagagatt ggcaaagcct ctcggaagga agtagtcgtt tagtgtatag ctagagttga
     5941 tgtgagttag cttttcctca gcctctgcta taagctcagc tttaccttgg ggttggacga
     6001 gatttagttg aggtttctct agctcaatct tgtgaggaag cttaacctca agctcgccct
     6061 ccatcttgta gagagccttg tcactagcct tgtcattggt tccctgatga taagggctgg
     6121 ctgtcatgat ggcagggatt tttccatcaa aacgagggcg aataatgcta acctttacta
     6181 ggtctgatag ccctttttgg tcagtatcga cacgagactc aacgtaaacg acttcacgaa
     6241 tgacatcctg gttagaaaaa gtagccaaac tcttgccgtt aaagtagtgg tagtcattat
     6301 cctccggaat aagaccatca ctaacaagtt ggtcgataag agtatttcct tttttggtgc
     6361 gagtattgag taactgatag agattttcaa tcaagtcacc atatataatg ggaaatccag
     6421 tttctttacg aaaaacgtca ctatcttcga agtcaaccaa ataagaaaag cctaaaagtt
     6481 gaaaagcaac agtataaaaa atatctgctg tcagttcatc ttctgattga aaaaatgtca
     6541 gcaggtctgt ttttttatca gctgctagga tagaaagtgg gtagttggtg tcttgataag
     6601 tgaaaaagaa acgacgtaaa aaggtttcaa gtgagtcttt gtgattggct gtattttgta
     6661 aatcaaagcc acattttttt agttcagata agacattttc ttttggaaaa ttgatataac
     6721 tatattgatt aaaacgcata gaacctccat atagaatgac agttaaggtt attatatcaa
     6781 aaaaaaagca gaaagggaat tgttaacttc aaaaggaaat aatccaataa aaatgaataa
     6841 agtactaaat tcaatataga gaacagagt
//
LOCUS       DAVLXH010000082         6749 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00028199
            SAMN33607166-rid17955573.denovo.083, whole genome shotgun sequence.
ACCESSION   DAVLXH010000082 DAVLXH010000000
VERSION     DAVLXH010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607166
            Sequence Read Archive: SRR23725544
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6749)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6749)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721421.1
            Genome Coverage       :: 115x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:42:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,210
            CDSs (total)                      :: 2,161
            Genes (coding)                    :: 2,023
            CDSs (with protein)               :: 2,023
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 73 of 138
            Pseudo Genes (incomplete)         :: 60 of 138
            Pseudo Genes (internal stop)      :: 40 of 138
            Pseudo Genes (multiple problems)  :: 31 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6749
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607166-rid17955573.denovo.083"
                     /strain="AUSMDU00028199"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1349"
     gene            441..1232
                     /locus_tag="VYO11_002019"
     CDS             441..1232
                     /locus_tag="VYO11_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1596513.1"
                     /translation="MNFALNKGEIVGLVGRNGVGKSTLMKILVQNNQPTSGNIISSDN
                     IGYLIEEPKLFLSKTGLENLKYLSNLYGVDYNQERFRSLIQELDLTQSINKKVKTYSL
                     GTKQKLALLLTLVTKPDILILDEPTNGLDIESSQIVLAVLKKLALNENVGILISSHKL
                     EDIEEICERVLFLESGLLTFQKVGKDSHNFLFEIAFSSATDRDIFITKQEFGDIVQEE
                     GLRITMSGNIQSSELFKFFNENSIKVVDFETKKETLKDIYLNRSK"
     gene            1248..1976
                     /locus_tag="VYO11_002020"
     CDS             1248..1976
                     /locus_tag="VYO11_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1596514.1"
                     /translation="MKLNKLNFLKENIRNLYSSGVIYLSLLISFIPPILLTFFILKTQ
                     ETSLGIKHISNFYAMLGMLMAVIHANRVISRDFSHNTVSLFYNQQKNRMIYVLSNFLY
                     AISVSIIYALNGIVLLVIVSKLGIPGDLGLDFIVAIVVNTILLVLFYFLLSYIFYLYK
                     LKSGLVFGILVALLLFIPNILNTMMMNTSNDLFIKAIELLPFYSLPVFVASNTMSISQ
                     YLVVITTIILLYFFTLKKSKKYSF"
     gene            2361..2570
                     /locus_tag="VYO11_002021"
     CDS             2361..2570
                     /locus_tag="VYO11_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1596515.1"
                     /translation="MAKNLKLKLARVERDLTQGQLAEAVGVTRQTIGLIEAGKYNPSL
                     SLCQSICRCLGKTLDQLFWEEEDEK"
     gene            2560..3048
                     /locus_tag="VYO11_002022"
     CDS             2560..3048
                     /locus_tag="VYO11_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1596516.1"
                     /translation="MKNRFYYYQLLDEREEQLFNKAGSESFYICIALSLLSYIISVLA
                     PSLFNSNMLLIVIIIGTFYFFNRARYLGVTYYSRFHFTILGCFFLTLAITALLMLQNY
                     QFNIEIYQHNPLNFKYLSAWVITYIIYLPWIFIGNLGLKSYGEWAQKKFEQDMDELES
                     GE"
     gene            3164..4624
                     /locus_tag="VYO11_002023"
     CDS             3164..4624
                     /locus_tag="VYO11_002023"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HEV1596517.1"
                     /translation="MYPDDSLTLHTDLYQINMMQVYFDQGIHNKKAVFEVYFRQQPFK
                     NGYAVFAGLERIVNYLEGLRFSDSDIAYLELLGYHGAFLNYLRNFKLELTVRSAQEGD
                     LVFANEPIVQVEGPLAQCQLVETALLNIVNYQTLVATKAARIRSVIEDEPLMEFGTRR
                     AQEMDAAIWGTRAAVIGGANGTSNVRAGKLFDIPVLGTHAHALVQVYGNDYEAFKAYA
                     ATHKNCVFLVDTYDTLRIGVPAAIQVARELGDQINFMGVRIDSGDIAYISKKVRQQLD
                     EAGFTEAKIYASNDLDENTILNLKMQKAKIDVWGVGTKLITAYDQPALGAVYKIVAIE
                     DETGQMRNTIKLSNNAEKVSTPGKKQVWRITSREKGKSEGDYITYDGVDISDMTEIKM
                     FHPTYTYIKKTVRNFDAVPLLVDIFKEGILVYNLPSLTDIQDYARKEFDKLWDEYKRV
                     LNPQHYPVDLARDVWQDKMDLIDKMRKEALGEGEEE"
     gene            4621..5445
                     /gene="nadE"
                     /locus_tag="VYO11_002024"
     CDS             4621..5445
                     /gene="nadE"
                     /locus_tag="VYO11_002024"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HEV1596518.1"
                     /translation="MSLQETIIQELGVKPVIDAQEEIRRSIDFLKRYLKKHPFLKTFV
                     LGISGGQDSTLAGRLAQLAMEELRSETGDDSYKFIAVRLPYGVQADEADAQKALAFIQ
                     PDVSLVVNIKESADAMTAAVEATGSPVSDFNKGNIKARCRMIAQYALAGSHSGAVIGT
                     DHAAENITGFFTKFGDGGADILPLYRLNKRQGKQLLQKLGAEPALYEKIPTADLEEDK
                     PGLADEVALGVTYAEIDDYLEGKTISPEAQATIENWWHKGQHKRHLPITVFDDFWE"
     gene            5843..6394
                     /locus_tag="VYO11_002025"
     CDS             5843..6394
                     /locus_tag="VYO11_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1596519.1"
                     /translation="MKSIGTQILQTERLILRRFVESDAEAMFQNWASSAENLTYVTWD
                     PHPDVEITRNSICNWVASYTNLNYYKWAICLKENPEQVIGDISIVKIDEADLSCEIGY
                     VLGKAYWGNGMMTETLKAILDFCFTQAGFQKVRARYASLNPASGRVMEKAGMSYLQTI
                     VNGVERKGYLADLIYYGISREEC"
BASE COUNT         2129 a         1112 c         1402 g         2106 t
ORIGIN      
        1 gtttaatgta gttgtttagt tttaaaaaat tatgcaaagc tccatataca acacttaaac
       61 gagattaaag aatggcgaaa tcccttgatg cgcaagagat tagctgtcct tttttatttt
      121 ttaagtgata aagtcggagc ttaggtatca aagcctatca aattaaacaa agaagtgatg
      181 tttagatatt ttgaaaaaaa ttaataagca gaaaactctc tattattttg ttgtagagag
      241 ttttttgtta ataaaatttt acaaaatgac atttatatat tgcattaagt tagatatatg
      301 atataatgtt gttaaaaaga ggcgcaactt tttaaactca ataagaatca aagagcaaac
      361 catgaatatt aatggaggaa taaaaaatgt aagttataaa tgtaagtaag cattatggtc
      421 attcaatcat tctcaaagat ataaattttg cacttaacaa gggtgaaatt gttggtctag
      481 tagggagaaa tggagttggt aagagtacgt tgatgaaaat tcttgttcag aataatcaac
      541 cgacttcagg taatattata agcagtgata atattgggta tttaatcgaa gaaccaaaat
      601 tatttttatc taaaacaggt ttagagaatt taaaatattt gtcaaattta tatggtgttg
      661 actacaatca agaaagattt agaagtttga tccaagagtt agatttgact cagtctatta
      721 ataaaaaagt aaagacctat tctttgggta caaaacaaaa attagctttg cttctaactc
      781 tcgttacgaa acctgatata ttgattttag atgaaccgac taatggttta gatattgaat
      841 catcacaaat agttttagcg gttctaaaaa aattagcttt aaatgaaaac gtgggaattt
      901 taatatcgag tcataaatta gaagacattg aagaaatttg tgagagggtt cttttcttgg
      961 agagcgggct tttgacattt caaaaagtag gaaaagatag tcataatttc ttgtttgaga
     1021 tagctttttc atcagctaca gatagagaca ttttcattac caaacaagaa tttggggata
     1081 ttgttcagga agagggactg agaattacta tgtctgggaa tattcaaagt agtgagcttt
     1141 ttaaattttt taacgaaaac tctattaaag tagttgattt tgaaactaaa aaagagacgc
     1201 ttaaagatat ttacttaaat cgttcaaaat aaaggaaggt tataatcatg aaattaaata
     1261 aattgaattt tcttaaggaa aatataagaa atttatattc atcaggcgta atatatctca
     1321 gtttgcttat ctcgtttata ccgccgatat tgcttacatt ctttattcta aagactcaag
     1381 agacatcgct tggtattaag catatttcaa acttttatgc tatgctcggt atgttaatgg
     1441 ctgttataca tgctaatcga gttattagta gagatttttc ccacaatacg gtaagtttgt
     1501 tttataatca acagaagaat cggatgattt acgtcttgtc taattttcta tatgccatct
     1561 cagtttccat tatttatgct ttgaatggca ttgtgttact agtcatagta agtaaattgg
     1621 gtattccagg tgatttagga ttagatttta tagtagctat tgtagtcaat acaattttgt
     1681 tagtcctgtt ttattttcta ttatcttaca ttttctattt atacaaattg aaaagtggct
     1741 tggtatttgg tattttagta gctttactac tctttatccc taatatatta aatacgatga
     1801 tgatgaatac tagtaatgat ttgtttatca aagcaattga acttcttcct ttttattctt
     1861 tacctgtatt tgtggcttca aatacgatgt ctattagtca gtatcttgtg gtaatcacta
     1921 caatcatttt attgtacttt ttcactctca agaaaagcaa gaagtattca ttttagtttc
     1981 atttagtatt attttgcata cctaaaatac agtaaaaaat cagtcatctt ggtatgctcc
     2041 tgctttcact attcaacacg tttttgactt atactaggct catttccaaa agcattatat
     2101 aatagtgata tgaaaccaac taaactaaac aagaaatata agcaataaaa attcgtttaa
     2161 aagatcttac taaagctaat actaaataaa aataaaagag taaactagga agtttatttc
     2221 aaacaaccta aaatactgat tttcggctga agataatact ggaatgcaaa ttaatggggt
     2281 tataataaat agctgatagc ttgtgttggt tttggatttt ttaagagtag atgagtatta
     2341 aaactataag gaggacgaag gtggctaaaa atttaaaatt aaaattagct cgggtagagc
     2401 gtgatttaac acaaggtcaa ctggcagagg ctgtcggggt gacacgccag actattggtt
     2461 taatagaggc gggaaaatac aatcccagtc tctcgctctg ccagtctatt tgcagatgtt
     2521 tagggaaaac cctagaccaa ctattttggg aggaagaaga tgaaaaatag attttattat
     2581 tatcaattac tagacgaaag agaagaacaa ctgttcaata aagcgggctc tgaaagtttc
     2641 tatatctgca ttgctttgtc gctcctatct tatatcattt cagtattagc accaagcctt
     2701 tttaattcta atatgctgct aatcgttatc atcataggga cattttactt tttcaatcgt
     2761 gcccgttatc tgggagtgac ctactatagt cgttttcatt ttacgatttt gggttgtttt
     2821 ttcctaacct tggctattac ggctcttttg atgttgcaga attatcaatt caacatagaa
     2881 atttatcagc acaatccttt gaattttaaa tacctgtctg cttgggtcat tacttatatc
     2941 atttaccttc cgtggatctt tattggcaat cttggtctta agagctatgg cgaatgggct
     3001 cagaaaaaat ttgaacaaga tatggatgaa ttggagagtg gagaatagct tgttactctt
     3061 ttctcaatcc agctaaaatg tgatataata gtactaattt attggaatac atgaaagttc
     3121 ttgaaaattt tcatgggttt ctagctaagg aagtaggaaa agtatgtatc cagatgatag
     3181 tttgacattg cacacggact tgtaccagat caacatgatg caggtttact ttgaccaagg
     3241 gattcacaat aagaaggcgg tctttgaggt gtatttccgc caacagcctt ttaagaacgg
     3301 ctatgcggtt tttgcaggtt tggaaagaat tgtgaactat cttgaaggct tgcgtttttc
     3361 agatagtgat atagcctatt tggagttgct tggttatcat ggggcgttct tgaattacct
     3421 tcgcaatttc aagttggagt tgaccgttcg ttctgcccaa gaaggggatt tggtttttgc
     3481 taatgaaccg attgtgcagg tggaaggacc tctagcccaa tgtcagttgg tcgaaacggc
     3541 tcttttgaac atcgtcaact accagacctt ggtggcgacg aaggcagctc gtattcgttc
     3601 ggttatcgaa gatgaaccct tgatggagtt tgggacacgt cgggctcaag aaatggatgc
     3661 ggccatctgg ggaacacgcg cagcggtgat tggtggcgcc aatggaacca gcaacgtgcg
     3721 tgcgggtaag ctctttgata ttcctgtttt gggaacccat gcccatgcct tggtacaggt
     3781 ttatggcaat gactatgaag ctttcaaggc ttacgctgcg acccacaaaa attgtgtctt
     3841 tcttgtggat acctatgaca cccttcgcat cggtgtacca gctgccattc aggtggcgcg
     3901 tgagctgggt gatcagatta actttatggg tgtgcggatt gactctgggg atattgccta
     3961 catttctaag aaagtccgtc aacaactgga cgaggctgga tttacagagg ctaagattta
     4021 tgcttctaat gatttggacg aaaatactat cctcaacctc aagatgcaaa aggccaagat
     4081 tgatgtctgg ggcgtgggta ccaagctgat tacagcctat gaccagccag ctcttggtgc
     4141 agtttacaag attgttgcaa tcgaagatga aactggtcag atgcgcaata cgattaagct
     4201 gtctaataat gcggaaaaag tctctacgcc aggtaagaag caggtgtggc gcattaccag
     4261 tcgtgaaaaa ggcaagtcag aaggcgacta tatcacttat gatggtgtgg atattagcga
     4321 catgacagaa atcaagatgt tccatccgac ctatacatac atcaagaaga cggttcgtaa
     4381 ttttgatgcc gttcctctct tggtggatat cttcaaagaa ggaatattag tttacaactt
     4441 gcctagtttg actgacattc aggattatgc ccgtaaggaa tttgacaagt tgtgggatga
     4501 gtataagcgt gtgctcaatc cgcagcacta tccagtggat ttggctcgtg atgtatggca
     4561 agataagatg gacttgattg ataagatgcg caaggaagcc cttggtgaag gagaagaaga
     4621 atgagtttgc aagaaacgat tatccaagag ctgggtgtca aaccagtgat tgatgcccag
     4681 gaagaaatcc gtcgttctat tgatttctta aaaagatatc tgaaaaaaca tcccttccta
     4741 aaaacctttg tactagggat ttctggggga caagactcaa ccttggcagg gcgtttggcg
     4801 caattagcta tggaagaact gcgatctgaa acgggagacg acagctacaa atttatcgct
     4861 gtccgcctgc catacggagt gcaagctgat gaagcagatg ctcaaaaagc tctagccttc
     4921 atccagccag atgtcagctt ggttgtgaat atcaaggaat cagctgatgc catgacagct
     4981 gcagttgaag cgacaggtag tcctgtttca gacttcaaca aggggaatat caaggcacgt
     5041 tgccgtatga ttgctcagta tgcccttgct ggttcccata gcggagcggt cattggaaca
     5101 gaccacgccg cggaaaatat cacaggtttc tttaccaagt ttggtgacgg cggtgcggat
     5161 attctccctc tttaccgcct caataaacgc caaggaaaac agctcttgca gaaacttggc
     5221 gcagagccag ccctttatga aaaaatccca acggcagacc tagaagaaga taaaccaggc
     5281 ctagctgacg aagtcgcact tggagtcacc tacgcagaga ttgacgacta cctagaaggc
     5341 aaaacaatca gcccagaagc tcaagcgacc attgaaaact ggtggcacaa aggccaacac
     5401 aaacgccact tacccatcac tgtatttgat gacttttggg agtaaaaacc tccattggag
     5461 gtttttaccc tgagcctaga aatgagaaag cgaagaaggt ccgggggact ttttagcttc
     5521 ttgccctgaa attaaaaagc aagaaaaacc tccactggag gttttcagcc tctcatcttg
     5581 aaataagaaa gtgagagaag gtctggggga tcttgaaccc cgagtttaga aataagaaaa
     5641 tgaggcagat tcagtaactc gaagagttcg atttcatcgt cttacccctg caacgatgac
     5701 taggtttgaa aaagcttgct agagcgcatt tcaaaccagg cagcaactgc gtcaagaaat
     5761 tagaagacaa actcgttttc tagctgttac tgagttgagc ctttttacta cgagtataga
     5821 aataaggaag tgaggtagca tcatgaaatc tatcggtacg caaatattac agacagaacg
     5881 tttgatttta agaagatttg tggagagtga tgcagaagcc atgtttcaaa attgggcttc
     5941 atccgctgag aatctgacct atgttacctg ggatccccat cctgatgtcg aaatcactcg
     6001 aaactcgatt tgcaattggg ttgcttccta tactaatctc aactattata aatgggccat
     6061 ttgtctaaaa gaaaacccag agcaagtgat aggagatatc agcatcgtta agatagacga
     6121 ggctgattta agctgtgaaa ttggctatgt gttaggcaag gcttactggg gaaatggtat
     6181 gatgacagag actttgaaag ctatcttgga cttttgtttt actcaagcag gttttcaaaa
     6241 ggtcagagca cgttatgcca gtctcaaccc agcttcaggt cgtgtcatgg aaaaggctgg
     6301 aatgtcctat ctacaaacca ttgttaatgg tgtagagaga aaaggctatc ttgcggatct
     6361 tatttattat ggtataagta gggaagaatg ttgaattcta ttttctgttt ctatcgaagt
     6421 caactattta ttgtaaatat aataattagc attccaagtt tatttgcaac tttaaaatag
     6481 catattgatt agtacaagac agatgttcta gttccttctt taatctggtt tagtattagt
     6541 taaaaaatcg ctttaagctt gtaactaaga gggagctaat cgactagatt ctccagccga
     6601 acaggtggta atgtactttt tatagtgtaa tcctagctgt tgttaaattt aaaatagaat
     6661 cctctatcga gttagggaat taaattcaac caattttatt catgtttttt ctatcaaatt
     6721 atctaatatt aaaatagtct cattctgat
//
LOCUS       DAVLXH010000083         6572 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00028199
            SAMN33607166-rid17955573.denovo.084, whole genome shotgun sequence.
ACCESSION   DAVLXH010000083 DAVLXH010000000
VERSION     DAVLXH010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607166
            Sequence Read Archive: SRR23725544
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6572)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6572)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721421.1
            Genome Coverage       :: 115x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:42:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,210
            CDSs (total)                      :: 2,161
            Genes (coding)                    :: 2,023
            CDSs (with protein)               :: 2,023
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 73 of 138
            Pseudo Genes (incomplete)         :: 60 of 138
            Pseudo Genes (internal stop)      :: 40 of 138
            Pseudo Genes (multiple problems)  :: 31 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6572
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607166-rid17955573.denovo.084"
                     /strain="AUSMDU00028199"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1349"
     gene            1..321
                     /locus_tag="VYO11_002026"
                     /pseudo
     CDS             1..321
                     /locus_tag="VYO11_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            491..691
                     /locus_tag="VYO11_002027"
     CDS             491..691
                     /locus_tag="VYO11_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000226586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1596520.1"
                     /translation="MVASASASSTSTQAQEQVDKSELRALSQELDQRLKALATVSDPK
                     IDATKAVLLDAQKVPEDSALTE"
     gene            716..1132
                     /locus_tag="VYO11_002028"
     CDS             716..1132
                     /locus_tag="VYO11_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1596521.1"
                     /translation="MKAALDSLKDVKANASDSKPAQDKKDAKQGTEDSKDSDKMTETN
                     SVPAGVIVVSLLALLGVIAFWLIRRKKESEIQQLSTELIKVLGQLDAEKADKKVLAKA
                     QNLLQETLDFVKEENGLAETETKLVEELKAILDKLK"
     gene            1363..2070
                     /gene="ccdA2"
                     /locus_tag="VYO11_002029"
     CDS             1363..2070
                     /gene="ccdA2"
                     /locus_tag="VYO11_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004237834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HEV1596522.1"
                     /translation="METIVFLISVFLAGVLSFFSPCIFPLLPVYAGILLDDQESAKSF
                     SLFGRKVLWSGLIRTLCFIAGISLIFFILGFGAGYFGHILYANWFRYGMGAIIIILGL
                     HQMEIFHLKKLEVQKSFTFKKSDSNRYWSAFLLGITFSFGWTPCIGPVLSSVLALAAS
                     GGNGAWQGAIYTLIYTLGMALPFLVLALASGLVMPYFSKIKRHMMLLKKIGGFLIVLM
                     GILLLLGQVNVLAGIFE"
     gene            2081..2638
                     /gene="sdbB"
                     /locus_tag="VYO11_002030"
     CDS             2081..2638
                     /gene="sdbB"
                     /locus_tag="VYO11_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     lipoprotein SdbB"
                     /protein_id="HEV1596523.1"
                     /translation="MKKVMFAGLSLLSLVVLMACGEEETKKTQAAQQPKQQTTVQQIA
                     VGKDAPDFTLQSMDGKEVKLSDFKGKKVYLKFWASWCGPCKKSMPELMELAAKPDRDF
                     EILTVIAPGIQGEKTVEQFPQWFQEQGYKDIPVLYDTKATTFQAYQIRSIPTEYLIDS
                     QGKIGKIQFGAISNADAEAAFKEMN"
     gene            3012..4403
                     /locus_tag="VYO11_002031"
     CDS             3012..4403
                     /locus_tag="VYO11_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001020339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEV1596524.1"
                     /translation="MNIFRTKNVSLDKTEMHRHLKLWDLILLGIGAMVGTGVFTITGT
                     AAATLAGPALVISIVISALCVGLSALFFAEFASRVPATGGAYSYLYAILGEFPAWLAG
                     WLTMMEFMTAISGVASGWAAYFKGLLSQYGIAFPQALNGTFNPQAGTFVDLLPILVLV
                     LVTSLVLLNAKAALRFNSILVILKFSALALFVLVGIWNIKFDNWSNFAPYGFGQIYGA
                     STGIMAGASLMFFGFLGFESISMAVDEVKTPQKNIPRGIVLSLSIVTILYALVTLVLT
                     GVVHYSHLNVDDAVAFALRSVGISWAANYVSLVAILTLITVCISMTYALSRMIYSLAR
                     DGLVPAAFKELTKTSKIPKNATILTGLASAVAAGMFPLASIAAFLNICTLAYLIMLAY
                     GLIRLRKEKGMPKAGEFKTPLVPLLPILSIIICLSFMLQYNMNTWIAFLVALLVGSII
                     YFTYGYKHSTIEE"
     gene            4546..5463
                     /gene="adcAII"
                     /locus_tag="VYO11_002032"
     CDS             4546..5463
                     /gene="adcAII"
                     /locus_tag="VYO11_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding lipoprotein AdcAII"
                     /protein_id="HEV1596525.1"
                     /translation="MKKQNLFLVLLSVFLLCLGACGQKESQTGKGMKIVTSFYPIYAM
                     VKEVSGDLNDVRMIQSSSGIHSFEPSANDIAAIYDADVFVYHSHTLESWAGSLDPNLK
                     KSKVKVLEASEGMTLERVPGLEDVEAGDGVDEKTLYDPHTWLDPEKAGEEAQIIADKL
                     SEVDSEHKETYQKNAQAFIKKAQELTKKFQPKFEKATQKTFVTQHTAFSYLAKRFGLN
                     QLGIAGISPEQEPSPRQLTEIQEFVKTYKVKTIFTESNASSKVAETLVKSTGVGLKTL
                     NPLEADPQNDKTYLENLEENMSILAEELK"
     gene            5471..>6572
                     /locus_tag="VYO11_002033"
     CDS             5471..>6572
                     /locus_tag="VYO11_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEV1596526.1"
                     /translation="MKINKKYLAGSVAVLALSVCSYELGRHQAGQVKKESNRVSYIDG
                     DQAGQKAENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIISE
                     ELLMKDPNYQLKDSDIVNEIKGGYVIKVNGKYYVYLKDAAHADNIRTKEEIKRQKQEH
                     SHNHGGGSNDQAVVAARAQGRYTTDDGYIFNASDIIEDTGDAYIVPHGNHFHYIPKSD
                     LSASELAAAQAYWNGKQGSRPSSSSSHNANPAQPRLSENHNLTVTPTYHQNQGENISS
                     LLRELYAKPLSERHVESDGLIFDPAQITSRTARGVAVPHGNHYHFIPYEQMSELEKRI
                     ARIIPLRYRSNHWVPDSRPEQPSPQSTPEPSPS"
BASE COUNT         2019 a         1221 c         1369 g         1963 t
ORIGIN      
        1 aaaaactatc ttactgataa tccagacgct tatttgactg aaatagcttc tgaatttggc
       61 tgtcatccaa ctaccatcca ctatgcactc aaagctatgg gctacactcg aaaaaaagaa
      121 ccacacctac tatgaacaag acccagaaaa agtagcctta tttcttaaga attttaatag
      181 tttaaagcac ctagcacagg tctaacaaat ggtgaattaa tcgctccaat gacttacgaa
      241 gagatgatga cgagcgactt ttttgaagta tggtttcaga agtttctctt accaacatta
      301 accacaccat cggttattat agcgaaatga aataagaaca ggacaaatcg atcaggacag
      361 taaaatcgaa ttctaacaat gttttagaag tccatatgta ctattctagt ttcaatatac
      421 cataactgtt cctagtcaac ctgcaagtcc tgtcccagct ccaagctcag ctccgactca
      481 agatcctaga gtggtagcaa gcgcttcggc tagctcaacg agcacacaag ctcaagagca
      541 agttgacaag tctgaacttc gtgccttgag tcaagagtta gaccaacgct tgaaagcttt
      601 ggcaacagta tctgatccga aaatcgatgc aaccaaggct gtcctcctag atgctcaaaa
      661 agttccggaa gatagtgcct tgacagagta aggtctgcat actgcagtag agtctgtgaa
      721 ggctgccttg gactctctca aagatgtgaa agcaaatgct agcgacagca agcctgcaca
      781 ggacaagaag gatgcaaaac aaggaacgga agatagtaag gattcagata agatgactga
      841 aacaaactca gttccggcag gagtgattgt ggtcagtcta cttgccctcc taggcgtgat
      901 tgccttctgg ctgattcgcc gtaagaaaga gtcagaaatc cagcaattaa gcacggaatt
      961 gatcaaggtt ctaggacagc tagatgcaga aaaagcggat aaaaaagtcc ttgccaaagc
     1021 ccaaaacctt ctccaagaaa cccttgattt cgtgaaagaa gaaaatggct tagcagagac
     1081 agaaactaaa ctagtagagg agcttaaagc aatccttgac aaactcaagt aaaacatgat
     1141 ttatgaaatg tcagacctaa aagacatttt cgttcacaaa agcagcgatg agtaatcctt
     1201 gtcgttgctt tttggctatt ttgggggata agatccgcct tgactagcaa aagaaaagat
     1261 tggtccaata gtgcccgata cgattttgcg tagcagaaag cttacaaata aaattgaata
     1321 tagtaaaata ggattagaat tattaagaaa gttggttctt tattggaaac gatagtattt
     1381 ttaatctctg tttttctagc aggtgtttta tccttttttt ctccttgtat ttttcctctt
     1441 ctgccagtct atgctgggat tttattggat gatcaagaaa gtgcaaaaag cttttctttg
     1501 tttgggagaa aggttctctg gtcaggcttg attcgaacac tttgctttat cgctggtatc
     1561 tctctcattt tctttattct aggctttggt gctggttact ttggtcatat tctctatgca
     1621 aattggtttc gatatggcat gggagctatt attatcattt tgggtcttca ccagatggaa
     1681 atttttcatt tgaagaaatt agaagttcaa aaaagtttta cctttaaaaa atcagattct
     1741 aatcgttatt ggtcagcttt tttacttggt attaccttta gctttggttg gacaccttgt
     1801 attggtccag ttttaagttc tgttttagca cttgcggctt ctggaggcaa tggcgcttgg
     1861 caaggagcga tttatactct catttacact ctgggcatgg cccttccttt cttggtattg
     1921 gcactagctt caggtctagt catgccatat tttagtaaaa tcaagcgtca tatgatgcta
     1981 ctaaagaaaa ttggtggttt cctcattgtt ttaatgggaa ttttgttact attaggacaa
     2041 gtaaatgttc tagctggaat ttttgaataa aggaggacaa atgaaaaaag taatgtttgc
     2101 tggcttaagt ctcttgtcat tagttgtatt gatggcctgt ggtgaggaag aaactaaaaa
     2161 gactcaagca gcacaacagc caaaacaaca aacgactgta caacaaattg ctgttggaaa
     2221 agatgctcca gacttcacat tgcaatccat ggatggcaaa gaagttaagt tatctgattt
     2281 taagggtaaa aaggtttact tgaagttttg ggcttcatgg tgtggtccat gcaagaaaag
     2341 tatgccagag ttgatggaac tagcggcgaa accagatcgt gatttcgaaa ttcttactgt
     2401 cattgcacca ggaattcaag gtgaaaaaac tgttgagcaa ttcccacaat ggttccagga
     2461 acaaggatat aaggatatcc cagttcttta tgataccaaa gcaaccacct tccaagctta
     2521 tcaaattcga agcattccta cagaatattt aattgatagc caaggaaaga ttggaaagat
     2581 tcaatttggt gctatcagta atgcggatgc agaagcagca tttaaagaaa tgaactagaa
     2641 tcgataaaat ctgattacaa gatgtagtca gattttggta acttctaaaa ctaacttcca
     2701 gtttcccaca acctagcttt tagtatgaga aaaacgcgtg acatcagtgg aaatccgtct
     2761 tagactaact tccactggtt ttctttttct tgatatataa gggttcaaaa gcgaaaagac
     2821 tcagaaaaag tgcacgacaa atagccctaa aacagagtcg tcttagagta acttccagtt
     2881 ttgggagaga gatggaagtt actttgagaa gttacggtag tcagattttt ttagaaaaac
     2941 attttataaa tattcacata tctcctatat ttatggtaaa atagaattat cagtttattt
     3001 tggagtcaaa gatgaatata tttagaacaa agaatgttag tttagataaa acagagatgc
     3061 ataggcattt gaagttatgg gatttgattt tgctgggtat cggagccatg gtagggacag
     3121 gcgtctttac aatcacaggt actgcagctg caacacttgc tggcccagcc ctagtgattt
     3181 caatcgttat ttctgccttg tgtgtgggat tatcagccct cttttttgca gaatttgcct
     3241 cgcgagtacc cgctacagga ggtgcctata gttacctcta tgctatctta ggagaattcc
     3301 ctgcctggtt ggctggttgg ttaaccatga tggagttcat gacagccata tcaggcgtag
     3361 cttcgggttg ggcagcttat tttaaaggct tgctctctca atacgggata gcctttcctc
     3421 aggctttaaa tggtaccttt aatcctcaag cagggacatt tgttgattta ttgcctattc
     3481 ttgtcttggt cttggtgact tcgcttgttt tactaaatgc caaggcagcc ttacgcttta
     3541 attcgattct agttattttg aaattttccg ctttagctct ctttgtttta gtaggaattt
     3601 ggaatattaa gtttgataat tggagcaatt ttgctcctta cggttttgga caaatctatg
     3661 gagctagcac tggtattatg gctggtgcgt ccttgatgtt cttcggtttt ttgggatttg
     3721 aatccatctc tatggctgta gatgaagtca agactcctca aaaaaatatt cctagaggga
     3781 ttgtcttatc gctttctatc gtaaccattc tctatgcctt ggtgaccctt gttttgactg
     3841 gtgtggttca ctatagtcat ttaaatgtcg atgatgccgt tgcctttgcc cttcgtagtg
     3901 ttgggattag ttgggcagcc aactatgtgt cattagtggc tatcttgacc ttgattacag
     3961 tttgtatttc gatgacctat gccctatcgc gtatgattta cagtttagca cgtgacggct
     4021 tagtgcctgc tgcctttaag gaactgacga agactagcaa gataccaaag aatgctacta
     4081 tcttgacagg tctagcttca gcagtagcag caggaatgtt cccactagcc agtattgcag
     4141 cctttttaaa tatttgtacc ttagcctact tgatcatgtt ggcttatggt ctgattcgct
     4201 tacggaaaga aaaaggaatg cccaaagctg gggaatttaa aacaccattg gtacctctgt
     4261 taccaatttt atcgatcatc atttgtttat ccttcatgtt acagtataat atgaatacct
     4321 ggattgcttt cctagttgcg ttgttagtag gaagtattat ttacttcact tatggctata
     4381 agcattctac catagaagaa taaagtgaaa gtctattgag ttgttgacac tcagcagatt
     4441 tttatatgtg aaagaaattt caaatttttt ctaaaaatat cttgacagat taaattttca
     4501 ggagtagaat atttactagt taattaaatg gttaaggagt tgttcatgaa gaaacaaaat
     4561 ttatttttag tcctgttaag tgtctttctt ttgtgcttgg gggcttgtgg tcaaaaggaa
     4621 agtcagacag gaaaggggat gaaaattgtg accagttttt atcctatcta cgctatggtt
     4681 aaggaagtat ctggtgactt gaatgatgtt cggatgattc agtcaagtag tggtattcac
     4741 tcctttgaac cttcggcaaa tgatatcgca gccatctatg atgcagatgt ctttgtttac
     4801 cattctcata cactcgaatc ttgggcagga agtctggatc caaatctaaa aaaatccaaa
     4861 gtgaaggtct tagaggcttc tgagggaatg accttggaac gtgtccctgg actagaggat
     4921 gtggaagcag gggatggagt tgatgaaaaa acgctctatg accctcacac atggctagat
     4981 cctgaaaaag ctggagaaga agcccaaatt atcgctgata aactttcaga ggtggatagt
     5041 gagcataaag agacttatca aaaaaatgcg caagccttta tcaaaaaagc tcaggaattg
     5101 actaagaaat tccaaccaaa atttgaaaaa gcgactcaga aaacatttgt aacacaacat
     5161 acagcctttt cttatctagc gaagagattt gggcttaatc aacttggtat tgcaggcatc
     5221 tctcctgaac aagaaccaag tccacgacaa ttaacagaaa ttcaggaatt tgttaaaacc
     5281 tataaggtta aaacgatttt tacagaaagt aatgcttctt caaaagtagc tgaaactctt
     5341 gtcaaatcaa caggtgtggg tcttaaaact ctgaatcctt tagaggcaga cccacaaaat
     5401 gacaagacct atttagaaaa tctggaagaa aatatgagta ttctagcaga agaattaaag
     5461 tgaggaaaga atgaaaatca ataaaaaata tctagcaggt tcagtggcag tccttgccct
     5521 aagtgtttgt tcctatgaac ttggtcgtca ccaagctggt caggttaaga aagagtctaa
     5581 tcgagtttct tatatagatg gtgatcaggc tggtcaaaag gcagaaaatt tgacaccaga
     5641 tgaagtcagt aagagagagg ggatcaacgc cgaacaaatc gtcatcaaga ttacggatca
     5701 aggttatgtg acctctcatg gagaccatta tcattactat aatggcaagg ttccttatga
     5761 tgccatcatc agtgaagagc tcctcatgaa agatccgaat tatcagttga aggattcaga
     5821 cattgtcaat gaaatcaagg gtggttatgt cattaaggta aacggtaaat actatgttta
     5881 ccttaaggat gcagctcatg cggataatat tcggacaaaa gaagagatta aacgtcagaa
     5941 gcaggaacac agtcataatc acgggggtgg ttctaacgat caagcagtag ttgcagccag
     6001 agcccaagga cgctatacaa cggatgatgg ttatatcttc aatgcatctg atatcatcga
     6061 agatacgggc gatgcctata tcgttcctca tggcaatcac ttccactata ttcctaagag
     6121 tgatttatct gccagtgaat tagctgctgc ccaagcctat tggaatggga agcagggatc
     6181 tcgtccttct tcaagttcta gtcataatgc aaatccagct caaccaagat tgtcagagaa
     6241 ccacaatctg actgtcactc caacttatca tcaaaatcaa ggggaaaaca tttcaagcct
     6301 tttacgtgaa ttgtatgcta aacccttatc agaacgccat gtagaatctg atggccttat
     6361 tttcgaccca gcgcaaatca caagtcgaac cgccagaggt gtagctgtcc ctcatggtaa
     6421 ccattaccac tttatcccct atgaacaaat gtctgaattg gaaaaacgaa ttgctcgtat
     6481 tattcccctt cgttatcgtt caaaccattg ggtaccagat tcaagaccag aacaaccaag
     6541 tccacaatcg actccggaac ctagtccaag tc
//
LOCUS       DAVLXH010000084         6181 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00028199
            SAMN33607166-rid17955573.denovo.085, whole genome shotgun sequence.
ACCESSION   DAVLXH010000084 DAVLXH010000000
VERSION     DAVLXH010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607166
            Sequence Read Archive: SRR23725544
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6181)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6181)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721421.1
            Genome Coverage       :: 115x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:42:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,210
            CDSs (total)                      :: 2,161
            Genes (coding)                    :: 2,023
            CDSs (with protein)               :: 2,023
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 73 of 138
            Pseudo Genes (incomplete)         :: 60 of 138
            Pseudo Genes (internal stop)      :: 40 of 138
            Pseudo Genes (multiple problems)  :: 31 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6181
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607166-rid17955573.denovo.085"
                     /strain="AUSMDU00028199"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1349"
     gene            complement(85..360)
                     /locus_tag="VYO11_002034"
     CDS             complement(85..360)
                     /locus_tag="VYO11_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002950996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HEV1596527.1"
                     /translation="MANKQDLIAKVAEATELTKKDSAAAVEAVFAAVADYLAAGEKVQ
                     LIGFGNFEVRERAERKGRNPQTGKEMTIAASKVPAFKAGKALKDAVK"
     gene            complement(466..1305)
                     /locus_tag="VYO11_002035"
     CDS             complement(466..1305)
                     /locus_tag="VYO11_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000161411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEV1596528.1"
                     /translation="MTKIKIVTDSSVTIEPELVKQLDITIVPLSVMIDNVVYSDADLK
                     EEGKFLQLMQESKNLPKTSQPPVGVFAEIFEDLCKDGGQILAIHMSHALSGTVEAARQ
                     GASLSTADVTVVDSSFTDQALKFQVVEAAKLAQEGKDMEAILSHVEEVKNHTELYIGV
                     STLENLVKGGRIGRVTGLLSSLLNIRVVMQMKDHELQPMVKGRGTKTFKKWLDELITS
                     LSERAVAEIGISYSGSDDWAKEMKESLQAYVEKPISVLETGSIIQTHTGENAWAILIR
                     YHS"
     gene            1447..2295
                     /locus_tag="VYO11_002036"
     CDS             1447..2295
                     /locus_tag="VYO11_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000592058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEV1596529.1"
                     /translation="MIKKIYPIFTILLGAAIYAFGLTYFVVPHHLFEGGATGITLITF
                     YLFKIPVSLMNLLINIPLFILAWKIFGAKSLYSSLLGTLALSGWLAFFEHIPLHIDLQ
                     GDLLITALIAGILLGIGLGIIFNAGGTTGGTDILARILNKYTHISIGKLLFILDFCIL
                     MLILLIFKDLRLVSYTLLFDFIVSRVIDLIGEGGYAGKGFMIITKRPDQLAKAINDDL
                     GRGVTFISGQGYYSKENLKIIYCIVGRNEIVKTKEMIHRIDPQAFITITEAHEILGEG
                     FTFEKE"
     gene            complement(2388..3305)
                     /locus_tag="VYO11_002037"
     CDS             complement(2388..3305)
                     /locus_tag="VYO11_002037"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HEV1596530.1"
                     /translation="MIITIPIKNQKDIGTPSDSVVVLGYFDGIHKGHQELFRVANKAA
                     RKDLLPIVVMTFNESPKIALEPYHPDLFLHILNPAERERKLKREGVEELYLLDFSSQF
                     ASLTAQEFFATYIKAMNAKIIVAGFDYTFGSDKKTAEDLKDYFDGEVIIVPPVEDEKG
                     KISSTRIRQAILDGNVKEAGKLLGAPLPSRGMVVHGNARGRTIGYPTANLVLLDRTYM
                     PADGVYVVDVEIQRQKYRAMASVGKNVTFDGEEVRFEVNIFDFNQDIYGETVMVYWLD
                     RIRDMTKFNSVDQLVAQLKADEEVTRNWS"
     gene            3743..3948
                     /locus_tag="VYO11_002038"
                     /pseudo
     CDS             3743..3948
                     /locus_tag="VYO11_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844775.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
     gene            complement(4259..4552)
                     /gene="rpmA"
                     /locus_tag="VYO11_002039"
     CDS             complement(4259..4552)
                     /gene="rpmA"
                     /locus_tag="VYO11_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HEV1596531.1"
                     /translation="MLKMTLNNLQLFAHKKGGGSTSNGRDSQAKRLGAKAADGQTVTG
                     GSILYRQRGTHIYPGVNVGRGGDDTLFAKVEGVVRFERKGRDKKQVSVYPIAK"
     gene            complement(4569..4913)
                     /locus_tag="VYO11_002040"
     CDS             complement(4569..4913)
                     /locus_tag="VYO11_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HEV1596532.1"
                     /translation="MIQAVFERAEDGELRSAEITGHAESGEYGLDVVCASVSTLAINF
                     INSIEKFAGYEPILELNEDEGGYLMVEIPKDLPSHQREMTQLFFESFFLGMANLSENS
                     SEFVQTRVITEN"
     gene            complement(4929..5243)
                     /gene="rplU"
                     /locus_tag="VYO11_002041"
     CDS             complement(4929..5243)
                     /gene="rplU"
                     /locus_tag="VYO11_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HEV1596533.1"
                     /translation="MSTYAIIKTGGKQVKVEVGQAVYVEKLNVEAGQEVTFNEVVLVG
                     GENTVVGTPLVAGATVVGTVEKQGKQKKVVTYKYKPKKGSHRKQGHRQPYTKVVINAI
                     NA"
     misc_feature    complement(5279..5366)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            complement(5431..6129)
                     /locus_tag="VYO11_002042"
     CDS             complement(5431..6129)
                     /locus_tag="VYO11_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004241810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HEV1596534.1"
                     /translation="MGGKMRLLPIRKISRQSKRLALFLTFCAGYVDAYTFIVRGNTLV
                     AGQTGNVVFLSVELIKNNVSDVRDKVLTLLAFMMGVFLLTIYKEKLRIVKKPILSLIP
                     LAILSIIIGFVPQTVDNIYLVPPLAFCMGLVTTAFGEVSGIAYNNAFMTGNIKRTMLA
                     FGDYFRTKHTPFLREGFIFVSLLSSFVLGVVFSAYLTIFYHEKTILGVPIMMSVFYLS
                     MLFASWQKKVKEKA"
BASE COUNT         1898 a         1266 c         1038 g         1979 t
ORIGIN      
        1 actctattta ttactagatt tcataattaa aaagcctact gaccaagcta gaaagcttga
       61 tacaataggc tttttaaaga ctgattattt aacagcgtct ttaagagctt taccagcttt
      121 gaatgctggt actttagaag ctgcaattgt catttcttta ccagtttgtg ggttgcgacc
      181 tttacgttct gcacgctcac gaacttcaaa gttaccaaaa ccgatcaatt gaactttttc
      241 accagctgca agatagtcag ctactgctgc aaatacagct tcaactgctg ctgctgagtc
      301 tttcttagtc aattctgtag cttctgctac tttagcgatc aaatcttgtt tgtttgccat
      361 gttaatgatt cctccagata atttctaatt aacaaatata atcatatcct aaaatccctt
      421 ttaggtcaag ttaaaaacgc tatttcttcc aattttattt attttttagg agtggtaacg
      481 tatcaaaata gcccaagcgt tctcacccgt gtgagtttga ataatggaac ccgtttccaa
      541 aacagaaatt ggcttttcaa cataagcttg taagctttct ttcatctctt ttgcccaatc
      601 atcactacca gaatatgaaa ttccaatctc tgctacagca cgttcagaaa gcgatgttat
      661 caactcatct aaccattttt taaatgtttt agttccacga cctttaacca ttggctgcaa
      721 ttcatggtct ttcatttgca tgacaacacg gatattgaga agggagctca acaagccagt
      781 tacacggcca attcgtccac ctttgacaag attttccaaa gttgaaacac caatataaag
      841 ctctgtatgg tttttaacct cttctacatg agataaaatt gcctccatat ctttaccttc
      901 ttgagctaac ttcgcagcct caacaacttg gaatttcagg gcttggtcag tgaaggaact
      961 atcaacaaca gtcacatctg cagtagatag gctagcacct tggcgtgctg cttctaccgt
     1021 acccgaaaga gcatgggaca tatgaattgc aagaatctgg ccaccatctt tgcataggtc
     1081 ttcaaaaatc tcagcaaaga cacctacagg tggctgactt gttttcggaa gattcttact
     1141 ttcttgcatc aactgaagaa atttaccttc ttctttcaaa tccgcatcag aataaacaac
     1201 attatcaatc attacagata atggaacaat tgtaatatct aattgcttta ctagttcagg
     1261 ttcaatagta acagatgaat cggttacaat cttaattttt gtcatagtat caatctttct
     1321 attttaggat tcagattggt ttccttactt ctaattatat caaaaaaaag attaaaaatc
     1381 ctaatggagt caatcaaatt ttccgtaaaa tttgatataa tcaacttata agaaaagagg
     1441 tgtcctatga ttaaaaaaat ttaccccatt tttaccattt tactaggtgc tgctatttat
     1501 gcttttggac tgacttattt tgtagttccc catcatctct ttgaaggagg ggcgacaggc
     1561 attaccctca tcacctttta tctttttaaa atccctgttt ccctcatgaa cctgctgatt
     1621 aatattcccc ttttcatcct agcttggaag atctttggag ccaaatccct ctattctagt
     1681 ttactaggaa ccttagcttt gtccggctgg ttagcttttt ttgagcatat tccccttcat
     1741 attgatcttc aaggtgattt actaatcaca gcccttatag cgggaatcct attgggaatt
     1801 ggccttggaa ttatttttaa tgctggaggt acaactggcg gaactgatat tctagctcgt
     1861 attctcaaca aatacactca tatatccata ggaaaactgc tctttatctt agatttttgt
     1921 attctcatgt tgattctcct aatcttcaag gatttgagat tggtttccta cacgcttttg
     1981 tttgatttta ttgtttctcg tgttattgat ttgattggtg aaggaggata tgccggcaaa
     2041 ggctttatga ttatcacaaa acgtcctgac caacttgcta aggcgattaa tgatgacctc
     2101 ggaagaggtg ttacttttat ttctggtcaa ggctactata gtaaagaaaa tttgaaaatc
     2161 atctactgta ttgtcggaag aaatgaaatt gtgaaaacga aggaaatgat tcatcgaatc
     2221 gatcctcaag cctttataac tattacagaa gcccatgaaa tcctaggaga aggcttcacc
     2281 tttgaaaaag aataaaaaga ggtaatgtcg tgacctcaaa agttagacta aatcatctat
     2341 cttttgggtt acagacaacc tcttttttgt tttatttact caagctctta agaccaattc
     2401 cgagttactt cttcatcagc ctttaactga gccactaatt ggtcaactga gttaaatttg
     2461 gtcatatctc gaatgcgatc aagccaataa accatgacgg tttccccata aatatcttga
     2521 ttaaaatcaa aaatattgac ttcaaaacgt acttcttctc catcaaaggt cacatttttc
     2581 ccgacactag ccatagcacg atacttctgt ctttgaatct caacatcaac gacataaacg
     2641 ccatctgctg gcatataagt acggtctaaa agcactaaat tcgctgtcgg ataaccaatt
     2701 gtacgaccac gagcattacc atgaactacc atacctcttg atggaagcgg tgcccccaaa
     2761 agttttcctg cttctttcac atttccatct aaaatagctt gacggatacg agttgaacta
     2821 atctttcctt tctcatcttc tacaggtgga acaatgataa cttctccatc aaagtaatcc
     2881 tttaaatctt ctgctgtttt tttgtcagaa ccaaatgtat aatcaaaacc tgcaacaata
     2941 attttggcat tcatagcctt gatataagtt gcaaagaatt cttgtgcagt gagactagcg
     3001 aattgactac taaaatcaag gagatataat tcttctacac cttcgcgctt tagttttctt
     3061 tcacgttcag cagggttcaa aatatgcaaa aacaaatctg gatgataagg ctctaaagcg
     3121 atctttggag attcattaaa ggtcataacg acgataggta ataaatcctt tctcgcagcc
     3181 ttgttggcaa cacgaaataa ttcttgatgc cccttatgta tgccatcaaa atagccgaga
     3241 acaacgactg aatcagatgg tgtgccaata tctttttggt tttttatagg aatagtaata
     3301 atcataaaat aattatatca tagcgatagc tatttctgga acagaaaatc tgaaatgttg
     3361 tttttttcac atgaagtgta cctgttttca aaaagcactt tattctatcg ttgcttaact
     3421 atgaactttg caatattctt ctcaaaaact tgtaggacat cttcaaaatt ttgcaaggag
     3481 tgattagact tgttcggtaa ccataaagtg tcatactatg cttatgtatg aaaaagcaat
     3541 gcaactaact cctgagaact ttaaattact aattggtgcc gaaaaggtag aatttagaat
     3601 cgaggtacac ctatggctgt aaaatttaca aaatgagaca acttgggcaa gatgtttgaa
     3661 gaatttccta aactccctga tttgaagcaa atcactttcc ctgatgacaa agaaaaaagc
     3721 caaaacagca aagaaaaact agatgactgc tttccaacaa ctcccatcta gtgtgcttca
     3781 gactgggcta tttttctctc catctgttag cttggattct cagaccgttt cagctaaaga
     3841 atatcttttc ccttatcaga aggaacggct caagccattc agacaagtga agggacgaca
     3901 agccaatatt tgaaaccaga tagcagttct tatagtcaat tgaaataaaa tctgaagaaa
     3961 tcgagtagga aactcatatc aatttttaac agtgttctat tccagattca tactcaataa
     4021 aaattaaagt gcaaactagg aagttagccg caggctgtac ttgagtacgg caaggtgaaa
     4081 ctgacggggt ttgaatttga ttttcgaaga gtatcaatcc actatacata ttaaaaagta
     4141 tgggtatcaa aataaaaaaa caggctctcc gaaaactcgg aaagccttat tttaagctgt
     4201 ttctagcttc ctaaccttta catttcaagg ttcgggataa aaggttcaat ggaccttttt
     4261 atttagcgat tgggtaaaca gaaacttgtt ttttatcgcg tcctttacgt tcaaagcgta
     4321 ctacgccttc aactttagcg aacaaagtat cgtctccacc acgaccaacg tttacacctg
     4381 gatagatgtg tgtaccacgt tgacggtaaa ggattgatcc acctgttaca gtttgtccgt
     4441 cagctgcttt agctccaaga cgttttgctt gtgaatcacg tccgtttgat gtagaacctc
     4501 cacctttttt gtgggcgaaa agttgcaagt tgttaagagt catttttaac ataatgtttt
     4561 cctccgtgtt agttttctgt gataactctg gtttggacga actcagaaga gttctccgat
     4621 aagtttgcca tacctaagaa aaatgattca aagaataact gggtcatttc tctctggtgt
     4681 gaaggaagat cttttggtat ttcaaccatc agatagccac cttcatcttc gtttaattct
     4741 aggattggtt catagcctgc aaatttctca atagaattga taaagttaat ggcaagcgta
     4801 gaaaccgatg cacacacgac atctaagccg tattcgccac tctcggcgtg tccagtaatt
     4861 tccgcactcc tcagctcgcc atcttcggct ctctcaaaga ctgcttgtat catgtgttct
     4921 ccttaaaatt aagcgttaat tgcgttgatg acaacttttg tatatggttg acggtgacct
     4981 tgtttacggt ggctaccttt tttaggtttg tacttgtaag taacaacttt cttttgtttt
     5041 ccttgttttt caacagttcc aactacagta gctccagcaa caagtggagt tccgacaaca
     5101 gtgttttcac caccaacaag aacaacttcg ttaaaagtaa cttcttgacc agcttcaacg
     5161 ttcaattttt caacgtaaac tgcttgacca acttcaactt taacttgttt tccgccagtt
     5221 ttgataattg cgtatgtgct cattatgcac ctcctatgat ttttatgggt ttccccgatt
     5281 ttttgtgaag actcgcctag catcgtggga cgaaccactt aaacttgaat aatcaagcaa
     5341 cgatgttcgt gcggttgcac aggatcgtgc atagtcaact cttcaagtat agcatatctc
     5401 ctattttctt acaagtaata acacctaaaa tcaagctttt tcttttactt ttttctgcca
     5461 agaggcaaaa agcatgctga ggtaaaaaac gctcatcata ataggaacac caagaatggt
     5521 cttttcatga tagaaaatcg tcaaataggc tgaaaagaca acgccaagga caaaactact
     5581 aagcaggcta acaaatatga atccttcacg caaaaaagga gtgtgcttgg ttcggaaata
     5641 atctccaaaa gccagcatgg tccgtttgat attccctgtc ataaaagcgt tattataggc
     5701 aatacccgac acttctccaa aagcagttgt caccagtccc atacagaagg ccaagggcgg
     5761 cactagatag atattatcca cagtttgcgg cacaaaacca ataatgattg ataagattgc
     5821 caagggaatc aaggacagaa taggtttttt cacaattctc aatttttcct tataaatcgt
     5881 taataaaaag actcccatca taaacgctag caaggtgaga accttgtccc taacatccga
     5941 aacattattt ttaattaatt ctactgaaag aaagacaaca tttccagttt gtccagctac
     6001 aagggtattc ccgcgaacaa taaaagtgta agcatccaca tatccagcac aaaacgtcaa
     6061 aaaaagtgct aaccttttag actgacgtga tatttttctt ataggtaata acctcatttt
     6121 acctcccatt gtattttctc ttagaaatat tgtaccattt tctttctaaa aaatcgtagg
     6181 c
//
LOCUS       DAVLXH010000085         5659 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00028199
            SAMN33607166-rid17955573.denovo.086, whole genome shotgun sequence.
ACCESSION   DAVLXH010000085 DAVLXH010000000
VERSION     DAVLXH010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607166
            Sequence Read Archive: SRR23725544
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5659)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5659)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721421.1
            Genome Coverage       :: 115x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:42:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,210
            CDSs (total)                      :: 2,161
            Genes (coding)                    :: 2,023
            CDSs (with protein)               :: 2,023
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 73 of 138
            Pseudo Genes (incomplete)         :: 60 of 138
            Pseudo Genes (internal stop)      :: 40 of 138
            Pseudo Genes (multiple problems)  :: 31 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5659
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607166-rid17955573.denovo.086"
                     /strain="AUSMDU00028199"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1349"
     gene            695..1753
                     /locus_tag="VYO11_002043"
     CDS             695..1753
                     /locus_tag="VYO11_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1596535.1"
                     /translation="MKDDQKYLLAGLYSLLVAIFYFPLIESKGIFVSILMAVLLLYLI
                     YFIATVIHIVIIKFIRKKSFKYLVLYPFTYDGSWRFQPINLLYFPEMVRDVIPINLVQ
                     EYCQGQPYGLLKKMLKRIRLSREISLLLATIIVYFFTHRILPLSVFTFIFSYILLFVQ
                     SYLGSNTAWIGNRRLIIDDEFEKILLSKSYIKEISSARYSEYLTCEYKNLTPIILIAI
                     FENLLDSYLLQNQSEVDLDIFYKVLPLLYKEKYTMGFNYFVSLNYLLYKVGFLGIIYD
                     NEALRDLSKQYLNKNISELQDGSFEVGIQDAVASKQIVVINEFIACLNSRCMPSQYDR
                     FFYKDRPYIFSRKSPIKG"
     gene            2068..3045
                     /locus_tag="VYO11_002044"
     CDS             2068..3045
                     /locus_tag="VYO11_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1596536.1"
                     /translation="MKNKRYFFDTILMILLLISTIFCVSPVFIKLDILGTPSHAILTF
                     VLAIPLFYILSQCLHTLLLLVSSIFCKLRPIYFYFIFVIIIGARKYYRILFHQLMGFS
                     PGIAVFYKESQTTKNLFKFYYFLYFTTLISYYFFFTFVYDKPLLLPLISFSIIIALVQ
                     KLYRIENQQLFLLKSKVLTILESKKNCEFNLQDYHEIWKLQSKSELPCVALSYISLIK
                     PYLSESVREQIDLLEIKRFKKINHPISLYGMLDVIKLNLYLRHYNEKNKYESMLKKIL
                     EVRPDFVLIEQNIDDSLNSSQPLSLSLAISEIQLLLEVYMGIKHVSIRR"
     gene            3422..3796
                     /locus_tag="VYO11_002045"
     CDS             3422..3796
                     /locus_tag="VYO11_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPH_0224 family bacteriocin-like peptide"
                     /protein_id="HEV1596537.1"
                     /translation="MELVLPNNYVALEQEEMMYLDGGFSIPRWPVATAINIAFNGVLG
                     GGAISLVRNYIRNYGLRRVTSAIAGVAARYVGVRVANRVAGFALSAINGFAAWMSIGD
                     AITTIWANNDVNRRDPNLNALW"
     gene            4004..4906
                     /locus_tag="VYO11_002046"
     CDS             4004..4906
                     /locus_tag="VYO11_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1596538.1"
                     /translation="MIRKLIIFLLMLPLFVLWLELHVLVNNLLLNLESPLDFVISMSL
                     AFCSLILSKIVLDILYALKDLYKKEALITIFPFIFIRRKKVNVRFSPYFSFHRKSLSP
                     DDLRSRIIWSFILEIAIILVFILKIPFAIIMLTTIFFWTIMDINHLVFNKTEFLFNQS
                     KWEKEDSFESDLTNTLKDKIQKSELSYSDLMSLQLYDAMNQSTFLTDSELFEDILKKI
                     EDSHNTLLCTGLVELLLYEISISNNNNWQEKVDKIRIQLIRINQLDFFYYTSWLRQNF
                     DFCMNREYHKMKSRKLLLSNKKIV"
     gene            4962..5201
                     /locus_tag="VYO11_002047"
     CDS             4962..5201
                     /locus_tag="VYO11_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HEV1596539.1"
                     /translation="MELVLPNNYVVIDEEVMMYLDGGAYLSKRACQGICAAAGVLATA
                     AGKIAYCIGYGVLNRGCDINGNPYPWDGFISATVR"
     gene            5198..>5659
                     /locus_tag="VYO11_002048"
     CDS             5198..>5659
                     /locus_tag="VYO11_002048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1596540.1"
                     /translation="MSNVDKIRKIHIIVCWVYIFLSFRAIINDTEYFLLIFLAFIYSI
                     VSLPLYSVKNKIVSICLAINSILLISFPILINKFFPESFLTYTVLISVFILELAIFHL
                     IGEDFDIKLTNEYKKISQFRSKVSQSPWIKYLEISSFILTIFPSILYGTVDN"
BASE COUNT         1890 a          725 c          980 g         2064 t
ORIGIN      
        1 tctattgaag atataaatta aaaatgaggc tgggaaaaaa ctcaatttga aaatgaaatt
       61 gagtaaattt ttctattata taacgcatat tatcaagatt tttgaacacc tgataatatg
      121 cacttttctt attttaaaga ttttttgcct ttcttcattt cttgaatgaa ttggagagat
      181 gactttattt aggtgtttga cattactata gataggattt agcagtacta atatgaactc
      241 atattatagg tgtagactta aattttggaa gcaagctaaa ggatatctta tctaggtaac
      301 taagtgctat aacaagatat attggtggag ttagtatggc aactattact aatgctctta
      361 atattgcgac tactgttgct gaagtcttct cattaggagg agctattgca tatggtttag
      421 atataataaa ataaatctaa taaattatat tattatagct cttggtatga tattggcatt
      481 aattttggta ttatcaagag tgtatagaaa atatttttat agagacgatg atgactaaag
      541 tttttatcaa taatttgggc tccttgtcaa ctgtagtggg ttgaagaaaa gctaacgtct
      601 ggggaagggg ttaaagcttt gctttatcaa atattgactt acagagttgc tctattgtat
      661 tgatgtattc ttagtaaata atatggtgtt ttgaatgaaa gatgatcaga aatatttatt
      721 agcgggactt tattcgcttc tagttgcaat attttatttt ccattgattg agtccaaggg
      781 gatttttgta agtatattga tggcggtttt acttttatat ttaatatact tcattgcaac
      841 agtcattcat attgtgataa ttaagtttat aagaaaaaaa tcttttaagt atttggttct
      901 atatccattt acttacgatg ggagctggag atttcaacct ataaacttac tctactttcc
      961 agaaatggtg agagatgtca ttccgattaa tttagttcaa gaatattgcc aaggacaacc
     1021 ttacggactg ttaaaaaaga tgctgaaaag aattcgattg tcacgagaga tatctttact
     1081 cctggctacc attatcgtct atttttttac gcatagaatt ctacctcttt cagtatttac
     1141 gttcatattt tcttacatat tgctatttgt acaatcttat ttgggtagca ataccgcttg
     1201 gattggaaat agaagattaa taatagatga tgaatttgaa aaaatcttgc tttcaaaaag
     1261 ttatataaaa gaaatatcat ctgcacgata ctcagaatac ttgacatgtg aatacaaaaa
     1321 ccttacacca atcatattga tagctatttt tgaaaatttg cttgactcct acttgcttca
     1381 gaatcagagt gaggttgact tagatatttt ttataaagtt ttacctttgc tttataaaga
     1441 aaaatatact atgggattca attactttgt aagtttaaat tatttactat ataaggttgg
     1501 atttttggga atcatttacg ataatgaagc attaagagat ttgtcaaaac aatatttaaa
     1561 caaaaatatt tcggaattac aagatggttc tttcgaggtc ggtatacaag atgctgttgc
     1621 ctctaaacaa atagtagtta taaatgaatt tatagcttgt ttaaattcca gatgcatgcc
     1681 atcccaatat gatagatttt tttataaaga tagaccttat attttttcca gaaagagtcc
     1741 tattaagggg tgaaaatttg ttacatttgg attaacaagt gtcctaggga ttagaaataa
     1801 ctctagtata gctagatatt tttgagtaac tagaaatatc attaggctac tcatatgatt
     1861 gccagaaaag atggctgatg aatcttattt atactgttgc agtaggcatt gtctaggata
     1921 aataagctat cttgatgggg gagattggaa taattttagt agaaacatta aaggattatg
     1981 gacaagtagc gcaggattag gtgatgcaat gtgctaagtt ggcttggtgt tagcagtagt
     2041 attatttaac aatggaaagt agactaaatg aaaaataaac gttatttttt tgacacaatt
     2101 ttaatgattt tactgcttat aagcacgata ttttgtgtca gcccagtatt tataaaattg
     2161 gacatcttag gaactccctc tcatgccatc ttaacctttg tattggcgat accgttattc
     2221 tatattttgt ctcaatgctt acatactttg ctattactag tttcctcaat cttttgtaaa
     2281 ttaagaccaa tttattttta ttttatattt gtgatcatta taggagctag gaaatactat
     2341 cgaattctct ttcaccaact aatgggattt agtccaggaa tagcagtgtt ttataaggag
     2401 agtcaaacaa ctaagaatct gtttaaattt tactacttct tgtactttac aacactaatt
     2461 tcatactatt ttttctttac ttttgtgtat gacaaaccgt tgcttttgcc tcttatttca
     2521 ttttctatta tcatagcatt agtacaaaaa ctttatagaa ttgagaatca acaattattt
     2581 ctgttaaaat caaaggtact aacaatactg gaatctaaga agaattgtga gtttaatctt
     2641 caggattatc atgaaatttg gaaattgcaa tcaaaatctg agttgccatg cgtggcttta
     2701 tcttatatca gtttgatcaa gccatatctt tcagagagcg tgcgtgaaca aattgattta
     2761 ttagaaatta agcgatttaa aaaaataaat catccaatat cactttatgg tatgttggat
     2821 gttataaaat taaatctata tttacggcat tataatgaaa aaaataaata tgaatcaatg
     2881 ttaaagaaaa ttttagaggt aagaccagac tttgttttaa tcgagcagaa tattgatgat
     2941 agtttaaata gctcgcaacc attatcttta tctttagcca tttcagaaat ccaacttttg
     3001 cttgaagtgt atatggggat caaacatgtt tcaattagga gataaaacca gaataatatt
     3061 tgccattata ggggcaagtt gcatattagt cagtatgtat cttattccac ttattaaaac
     3121 tgagaataaa ttttgggaaa tacttttatt tatattaggt gtattgctaa ttggaattgc
     3181 gttactaagt caaaaaaaat aaattttgaa atagtattag tgagttcgca atcatttatt
     3241 gctagtggtt tagaactgtt aagtttcaaa caataattga ttttaaacct taggtaacct
     3301 ataaaaacaa ataaggtaga gaaaggatat cttatctagg tagctaagtg ataaaaacac
     3361 agtcgtctat cacttgttag gaaactatcc taactatgct taataaaaaa ggagaaaata
     3421 aatggaactc gtattaccaa ataattatgt tgctcttgag caagaagaga tgatgtatct
     3481 tgatggggga ttttctattc cgagatggcc tgttgcaaca gccattaata tagcttttaa
     3541 tggtgtttta ggtggaggag caatcagtct agttagaaat tatattcgta attatggttt
     3601 gcggcgagtt acaagcgcaa ttgctggagt agctgcaaga tatgttgggg tacgagttgc
     3661 aaatagagtg gcaggatttg cactgtctgc tattaatgga tttgcagctt ggatgtcaat
     3721 tggtgatgct attacaacaa tctgggccaa caatgatgta aataggagag acccaaattt
     3781 aaacgccttg tggtaactag atatgggtat taaaatggaa aaaatttttg ttattatttt
     3841 ttttgtatgt ctatttatat catccataac ttttttagcc tatgattttg ttagcgaaga
     3901 aataaaaaag ttgattattt ggattaatgt cgtttttttg attttaatca tagcaatgat
     3961 aatttatcca aaattaagaa aatgataagg acactgtaaa attatgatac gtaaactaat
     4021 cattttttta ttaatgctcc ctctttttgt cttgtggcta gagttgcatg tcctagtgaa
     4081 taacttacta ttgaatctag aatctcccct tgattttgtg attagtatga gtcttgcttt
     4141 ctgtagtttg attttatcaa aaatagtttt agacatacta tacgcattga aagatttgta
     4201 caagaaagaa gctcttatta cgatttttcc ctttattttt ataagaagga aaaaagtgaa
     4261 tgtgagattc tcgccctatt tttcattcca tcgtaaaagt ttgtcgcctg atgatttaag
     4321 atctaggatt atatggagtt ttattcttga aattgctatt atcctagtat ttattttaaa
     4381 aattcctttt gcaatcatca tgcttactac aatatttttc tggactataa tggatatcaa
     4441 tcatctcgtt tttaataaga cggaatttct tttcaatcaa agtaaatggg aaaaagaaga
     4501 ctcgtttgaa agtgatttga caaatacgtt aaaggataag atacaaaaat cagagctaag
     4561 ttattctgac ttaatgtctc ttcagctgta tgatgcgatg aaccaatcca cctttttaac
     4621 ggatagtgaa ctttttgagg atattttgaa aaaaatcgaa gattctcata acacccttct
     4681 gtgtacaggt cttgtcgagt tactgctgta tgagatttct attagtaaca ataacaactg
     4741 gcaagaaaag gttgataaaa ttagaataca gctcatcaga ataaatcaat tagatttttt
     4801 ctattataca agttggttaa ggcaaaattt tgatttctgt atgaatagag agtatcataa
     4861 aatgaaatct cggaaattat tactgagtaa taaaaagata gtttaagttc gtcctatttg
     4921 taaaacaaat gaaacaattt caactaagga ggagaaaaca aatggaactt gtattaccaa
     4981 ataattatgt tgtgattgat gaagaagtaa tgatgtatct tgatggggga gcttatttaa
     5041 gcaagcgtgc ttgtcaagga atttgcgcag cagcaggtgt attggctaca gcagcaggga
     5101 aaatagctta ctgtattgga tatggtgttc ttaatagagg ttgtgatatt aacgggaacc
     5161 cttatccttg ggatggattc atatctgcaa cagtaagatg agtaatgtag ataagattcg
     5221 aaaaatacac atcatcgtgt gttgggtgta tatattttta tcattcaggg cgattataaa
     5281 tgatacggag tattttttgc ttattttttt agcttttatc tactcaatag tatcactacc
     5341 tctatattct gtgaaaaata aaatagtatc tatctgtcta gccataaatt cgattctgtt
     5401 aatcagtttc cccattttaa tcaataagtt tttcccagaa agttttttga cttataccgt
     5461 attaataagt gtttttatcc tagagttagc aatctttcat ttaattgggg aagattttga
     5521 tattaaattg actaacgaat ataagaaaat tagtcagttt agaagcaagg tgtctcaatc
     5581 tccttggata aaatatttag agatttctag ttttatatta actatatttc catctattct
     5641 ttacggtaca gttgataat
//
LOCUS       DAVLXH010000086         5187 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00028199
            SAMN33607166-rid17955573.denovo.087, whole genome shotgun sequence.
ACCESSION   DAVLXH010000086 DAVLXH010000000
VERSION     DAVLXH010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607166
            Sequence Read Archive: SRR23725544
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5187)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5187)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721421.1
            Genome Coverage       :: 115x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:42:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,210
            CDSs (total)                      :: 2,161
            Genes (coding)                    :: 2,023
            CDSs (with protein)               :: 2,023
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 73 of 138
            Pseudo Genes (incomplete)         :: 60 of 138
            Pseudo Genes (internal stop)      :: 40 of 138
            Pseudo Genes (multiple problems)  :: 31 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5187
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607166-rid17955573.denovo.087"
                     /strain="AUSMDU00028199"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1349"
     gene            55..888
                     /locus_tag="VYO11_002049"
     CDS             55..888
                     /locus_tag="VYO11_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase family
                     protein"
                     /protein_id="HEV1596541.1"
                     /translation="MNPLKECYEKNGILIAAHRGTNGGNILQNTSKAYLNSIRHNADM
                     FEVDVIRSKDGEFFAFHDGQEPLVFGEKIDIRTLSSEEIQRKECFNSLNEPILQKIEK
                     ISDVLKNFEGQSLINIDRSWFYWDTFLDKLKTYPSLNQVLLKSPVKKELLEMLRDSGL
                     NVMYMPIIKTIEELDFVLSFEGINTVAVELVFQDLENPIISKKIIDDLHEKGLLIWVN
                     ALTLSDSIILSAKIDDDTAIAHDGESWGKLVSIGFDIIQTDWPLLLYQYLVEKNKKIK
                     K"
     gene            907..1968
                     /locus_tag="VYO11_002050"
     CDS             907..1968
                     /locus_tag="VYO11_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000475757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEV1596542.1"
                     /translation="MFKNFKKIAFTSSLILLAACSNNASNTNQSTDEGSVDKSQEIVI
                     YTNSASNGRADWLQTKASEQGYNLRLVDISGGELADRLIAEKNNAVADMVIGLNKLEF
                     NRIKAEKLLVKYSPKWADEVDSSLGDSEGYYSPIVNQPLVLIGNKDAKMPSDWTDFTD
                     SSYKGKYGISKLSTGTSKNIFASIVSRYKDEKGELGISDEGWKVAKAYLKNAHVYAEG
                     EDYISSIMDNNNDLKYSMMWGSGVLQNQKEREYKFQVMSPKVGVPYVTEQVGILNTSK
                     KQALLKEFVDWFGSSELQKEWSDKFGSIPANKKALEQAKDELKQFANSVKPQELDWEF
                     IGKNIDSWIEKAQLEFVEQ"
     gene            1985..2989
                     /locus_tag="VYO11_002051"
     CDS             1985..2989
                     /locus_tag="VYO11_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1596543.1"
                     /translation="MITFKDIQIKYNDFIAIDNLNLTINEGEFFTFLGPSGCGKSTTL
                     RALVGFLEPSQGQILVDNQDITNLDPEKREIGIVFQSYALFPTMTVFDNIAFGLKVKK
                     VSPEIIKAKVHEIAKKINISDEQLNRNISELSGGQQQRVALARALVLEPKILCLDEPL
                     SNLDAKLRVSLRKELKRLQKELGITTLYVTHDQEEALTLSDRIAVFNNGFIEQVGTPY
                     DIYNQSATQFVCDFIGSINKISQEVLKKLQGENKYFKETEGYIRLERVKLEKTSPQDL
                     SITGVISDIEFNGVLIKYKVDLSNSESIHIIEKNDGLSRHIIKEKVTMYINPRDIMQF
                     "
     gene            3001..4695
                     /locus_tag="VYO11_002052"
     CDS             3001..4695
                     /locus_tag="VYO11_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEV1596544.1"
                     /translation="MRKSLNWKDCLIRLGVLWLIFALIIYPNIELLSGVFYKNGSFTL
                     EAFNKIIHSQRAMSSIFNSFILAISMVFTVNIVGTLIVLLTEYWDIRGSKILKLGYMS
                     SLVYGGIVLATGYKFVYGANGLVTKTLSSIIPGLAPNWFQGFGAVLFIMTFACTSNHI
                     MFLTNAVRSVDYHTIEAAKNMGASPLKVFFSVVFPTFKPTLFALTILTFLTGLSAVSA
                     PLIVGGKDFQTINPLIISFAKTTSSRDLAALLAIMLGLATILLLTLLNHVEKGGNYVS
                     VSKTKASIKKQIISSPLWNTLAHIVAYVLFAIYMLPIVLIILYSFTDSLTIKTGTLDL
                     SKFTLANYANLFTDAQSFRPYLVSVVYAILAAVIATIIAIVISRIVHKNKSKFDKFFE
                     YGALIPWILPGTLIALGLMFTYNIPHLILFNLVLVGTVIILLIAYTIQKLPFSYRMIR
                     AVFFSIDNDMEEAARSMGASSFYTMVRVIIPYILPVVLSVVVLNFNSLLSDYDLSVFL
                     YHPLFQPLGIVIKQSTDETATLNAQAMMFVYSVILMIMSSAALYLSSLFQGKRGKR"
     gene            4697..>5187
                     /locus_tag="VYO11_002053"
     CDS             4697..>5187
                     /locus_tag="VYO11_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001054457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HEV1596545.1"
                     /translation="MNLSYELSIWEILLRCFLAILFGGIVGYERGVKNQAAGIRTYLL
                     VCLGTCVVMMTNQFITSRYGSGDPSRMGAQVISGLGFLGAGTIMVTNQKVKGLTTAAG
                     LWSSATIGLAIGIGFYEGAILAGVVLIAVLTLFTPLKDYLNSKTKIADYYLVFSSLEG
                     YNR"
BASE COUNT         1767 a          728 c          956 g         1736 t
ORIGIN      
        1 cgttccaaga aatcggatac aatgtaatta acaataaaga taggagaaaa taatttgaat
       61 ccattaaaag aatgctatga aaaaaacggt atactaattg cagcacaccg tggtacaaac
      121 ggaggaaata tattacaaaa cacatcaaaa gcctatttga attccatacg ccataacgca
      181 gatatgtttg aggttgatgt aattcgttca aaagatggag aattttttgc atttcacgat
      241 gggcaagaac ctttagtatt tggtgaaaaa attgatatta gaactttgag ttctgaagag
      301 atccaaagaa aggaatgttt taattcactg aatgaaccca tattacaaaa gattgaaaaa
      361 atttctgatg tattaaaaaa ttttgaggga cagtctttaa taaatataga tagaagttgg
      421 ttttactggg ataccttcct agataagtta aaaacatatc catctttgaa tcaagttctt
      481 ttaaaatcac ctgtaaaaaa agaattattg gaaatgctta gagactctgg tttgaatgtt
      541 atgtatatgc caattatcaa aacaattgaa gagttagatt ttgttctctc atttgaagga
      601 ataaatacag tagctgtcga acttgtattc caagatttag aaaatccaat cataagtaag
      661 aaaataattg atgatttaca tgaaaaagga ttacttattt gggttaatgc tttaacctta
      721 agtgattcaa ttattctttc ggctaagatt gatgatgata cagctattgc tcatgatggc
      781 gaatcttggg ggaaattggt ttcaatagga tttgatatta ttcaaacaga ttggccatta
      841 ttactttatc aatatctagt tgaaaaaaat aaaaaaataa aaaaataaaa ataaaggaga
      901 actatcatgt tcaaaaactt taaaaagatt gcattcactt cttcactaat tttacttgct
      961 gcttgctcaa acaatgcttc aaatacaaat cagtctactg atgaaggaag tgttgataaa
     1021 tctcaagaaa ttgtaatcta tacaaattcg gcttctaatg gacgtgcaga ttggttacaa
     1081 actaaagcat cagagcaagg atacaatctt cgtttggtag atatttcagg tggagaacta
     1141 gctgaccgtt tgattgcaga aaagaataat gctgtggctg atatggtaat tggattaaat
     1201 aaattagaat ttaaccgtat taaagctgaa aaacttcttg taaaatactc accaaaatgg
     1261 gctgatgaag tagatagctc tttgggagat tctgaagggt attattcacc aattgtaaat
     1321 caaccattag ttttgattgg taataaagat gctaaaatgc catccgactg gacagatttt
     1381 actgattcat cttataaagg taaatatggt atttcaaaat taagtacagg tacatctaag
     1441 aacatctttg caagtattgt ttcgagatat aaagatgaaa aaggtgagtt aggaatatct
     1501 gatgaaggtt ggaaagttgc aaaagcttac cttaaaaatg cacacgttta tgcagaaggt
     1561 gaagactata tctcttcaat tatggataat aataatgatc taaaatatag tatgatgtgg
     1621 ggatctggtg ttctacaaaa tcaaaaagaa cgtgaatata aattccaagt aatgtcacca
     1681 aaagttggtg ttccttatgt aactgaacaa gttgggattt taaatacaag taagaagcaa
     1741 gcattattaa aagaatttgt agattggttt ggctcttcag aacttcaaaa agaatggtct
     1801 gataaatttg gttcaattcc agctaataaa aaagctctag agcaagcaaa agatgaactc
     1861 aaacagtttg ctaatagtgt taaaccacaa gaacttgact gggagtttat cgggaaaaac
     1921 atcgattctt ggattgaaaa agcacagctt gaatttgttg aacaataata gttaggatta
     1981 agtgatgatt acatttaagg atattcaaat taagtataat gattttattg ccatcgataa
     2041 tctcaattta acaatcaatg agggagagtt tttcacattt ttaggaccaa gtggttgtgg
     2101 gaaatcaaca actcttcgtg cactagttgg atttttggag ccttcacagg ggcaaatact
     2161 agttgataat caagatatta cgaatttaga tccggaaaaa cgcgaaattg gtattgtgtt
     2221 tcaaagttat gcattattcc caacaatgac tgtttttgat aatattgctt ttggtctaaa
     2281 agttaaaaaa gtttctcctg aaattattaa agctaaagtt catgaaattg cgaaaaaaat
     2341 taatatctca gacgagcaac taaaccgaaa tatttctgaa ttatcagggg gacaacaaca
     2401 gcgtgtagct ttagcacgtg cattagtatt agaaccaaaa attctttgtt tggatgaacc
     2461 gttatcaaac ctagatgcca aactacgagt ttcgttgaga aaagaattga aacgattgca
     2521 aaaagaacta ggaatcacta ctctttatgt cacacatgat caagaagaag cattaacatt
     2581 atcagatagg attgctgtgt ttaataatgg atttattgag caagttggca cgccgtatga
     2641 tatttataat caatccgcaa ctcaatttgt ctgtgatttt attggctcaa tcaataaaat
     2701 tagccaagaa gttcttaaaa aattacaagg cgagaataaa tactttaaag aaactgaagg
     2761 atacatacgc ttagagcgtg ttaagttaga gaaaacttca cctcaagatt tatctataac
     2821 aggggtaatt agtgatattg agtttaatgg tgtacttatt aagtataaag tagacttgtc
     2881 gaatagtgaa agtattcata ttatcgaaaa gaatgatgga ctatcacgtc atataatcaa
     2941 agaaaaagtc actatgtaca ttaatccgcg tgatataatg caattttaag gagattgtgc
     3001 atgagaaaga gtctaaactg gaaagattgt ctcataagat taggagtttt atggctaatc
     3061 tttgccctga ttatttatcc aaatattgaa cttttgtctg gagtgtttta taaaaatggt
     3121 tcatttactc tagaggcatt caataagatt atacactctc agagagcgat gagtagtata
     3181 tttaatagct ttattttggc gatttcaatg gtctttactg taaatattgt tgggacattg
     3241 attgttctac tcacagagta ctgggatatt aggggttcaa aaatacttaa attaggttat
     3301 atgagctctc tagtatatgg aggaattgta ttagcgacag gatataaatt tgtttatggc
     3361 gctaatggtc ttgtaactaa aacgctctca agtataattc caggtcttgc ccctaactgg
     3421 tttcaaggat ttggtgcagt attgtttatt atgacatttg cttgtacctc aaatcacata
     3481 atgtttttaa caaatgcagt tcgtagtgtt gattatcata caattgaggc agctaaaaat
     3541 atgggtgcaa gtcctttaaa agttttcttt agtgtggttt ttccaacttt taaacctacg
     3601 ttatttgcct taaccatctt aacttttttg acaggtcttt cagcagtttc tgctcctttg
     3661 atagtagggg ggaaagattt tcaaactatt aacccattga ttatcagttt cgctaaaact
     3721 acaagttcga gagatttagc agctttacta gctatcatgt taggtttagc aactattcta
     3781 ttattgacac ttttgaatca tgtcgaaaaa ggaggtaatt atgtatctgt ttcgaaaacc
     3841 aaggctagta ttaagaagca gataatttct tctccattat ggaatactct tgctcacatt
     3901 gttgcgtatg tattgtttgc aatctatatg ttaccaatag ttttgataat tctatactcg
     3961 tttacagact cgttgacgat caagacggga actttagatc tatctaaatt tacgttagcg
     4021 aactatgcta atttatttac agatgctcaa tcatttcgtc cttacctagt cagcgttgtt
     4081 tatgcaattt tagctgcggt aattgctaca attatagcaa tagtaatttc acgtattgta
     4141 cataaaaaca agagtaagtt cgataaattc tttgagtatg gtgcactgat accatggata
     4201 ttgccaggta cattgattgc actaggatta atgttcactt ataatatacc tcatttaata
     4261 ctatttaatt tagttttagt aggaacagta attattttac ttattgcata tactattcaa
     4321 aaattaccat tttcttatag aatgattcgg gctgtatttt tcagtataga taatgatatg
     4381 gaagaagctg cacgtagtat gggtgcatct agtttctaca ctatggtgcg agttattata
     4441 ccgtatattt taccagtcgt attatcagta gttgtgttaa actttaattc tttattatct
     4501 gactatgact tatctgtatt cttgtaccat ccacttttcc aaccattggg aatcgttatt
     4561 aaacagtcta ctgatgaaac agcaacttta aatgcacagg caatgatgtt tgtttattct
     4621 gtaattttaa tgattatgtc tagtgcagct ctttatttat caagcctatt ccaaggtaaa
     4681 cgaggtaaga gataatatga atctttcata cgaactgagt atttgggaaa tacttcttag
     4741 gtgcttttta gcgattcttt tcggtggcat tgttggctat gagcgaggag tcaaaaacca
     4801 agcagcaggg attagaacct acttactagt ttgtttggga acttgtgttg taatgatgac
     4861 aaatcagttc atcactagtc gttatggtag cggtgatcct agtcgaatgg gagcccaagt
     4921 aattagtggc ttgggtttcc taggggcagg aacaatcatg gtaactaatc aaaaagttaa
     4981 aggtttaaca acagcagctg gattatggtc ttcagcaact attggtttag ctataggcat
     5041 tggtttttat gaaggtgcta ttttagccgg agttgtactc atagcagttt taactctatt
     5101 tactcctctt aaagattatt taaactcgaa aactaaaatt gctgattact acttggtttt
     5161 tagttcttta gaaggttata atcgttt
//
LOCUS       DAVLXH010000087         5111 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00028199
            SAMN33607166-rid17955573.denovo.088, whole genome shotgun sequence.
ACCESSION   DAVLXH010000087 DAVLXH010000000
VERSION     DAVLXH010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607166
            Sequence Read Archive: SRR23725544
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5111)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5111)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721421.1
            Genome Coverage       :: 115x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:42:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,210
            CDSs (total)                      :: 2,161
            Genes (coding)                    :: 2,023
            CDSs (with protein)               :: 2,023
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 73 of 138
            Pseudo Genes (incomplete)         :: 60 of 138
            Pseudo Genes (internal stop)      :: 40 of 138
            Pseudo Genes (multiple problems)  :: 31 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5111
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607166-rid17955573.denovo.088"
                     /strain="AUSMDU00028199"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1349"
     gene            60..503
                     /locus_tag="VYO11_002054"
     CDS             60..503
                     /locus_tag="VYO11_002054"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HEV1596546.1"
                     /translation="MKIRGFELVSSFTDENLLPKRETAHAAGYDLKVAVRTVVAPGEI
                     VLVPTGVKAYMQPTEVLYLYDRSSNPRKKGLVLINSVGVIDGDYYGNPGNEGHIFAQM
                     KNITDQEVVLEVGERIVQAVFATFLIADGDAADGVRTGGFGSTGH"
     gene            505..1020
                     /locus_tag="VYO11_002055"
     CDS             505..1020
                     /locus_tag="VYO11_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEV1596547.1"
                     /translation="MKIIFVRHGEPDYRELEERSYIGFGIDLAPLSEMGRQQVQKLSK
                     NPLLSSAEIIVSSAVTRALETASYVVCATGLPLKVEPLLHEWQVYKTGIENFETARRL
                     FLENKGELLPNSPIQYETATEMKSRFLECMSKYREHQTVVVVAHRMLMRQFVPNEKID
                     FCQVIECELEI"
     gene            1034..2395
                     /gene="radA"
                     /locus_tag="VYO11_002056"
     CDS             1034..2395
                     /gene="radA"
                     /locus_tag="VYO11_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000336571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HEV1596548.1"
                     /translation="MAKKKATFVCQNCGYNSPKYLGRCPNCGSWSSFVEEVEVAEVKN
                     ARVSLTGEKTKPMKLAEVTSINVNRTKTEMEEFNRVLGGGVVPGSLVLIGGDPGIGKS
                     TLLLQVSTQLSQVGTVLYVSGEESAQQIKLRAERLGDIDSEFYLYAETNMQSVRAEVE
                     RIQPDFLIIDSIQTIMSPEISGVQGSVSQVREVTAELMQLAKTNNIAIFIVGHVTKEG
                     TLAGPRMLEHMVDTVLYFEGERHHTFRILRAVKNRFGSTNEIGIFEMQSGGLVEVLNP
                     SQVFLEERLDGATGSSIVVTMEGTRPILAEVQALVTPTMFGNAKRTTTGLDFNRASLI
                     MAVLEKRAGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKDKPTNPQECFVGE
                     LGLTGEIRRVNRIEQRINEAAKLGFTKIYVPKNSLTGITLPKEIQVIGVATIQEVLKK
                     VFA"
     gene            2468..2965
                     /locus_tag="VYO11_002057"
     CDS             2468..2965
                     /locus_tag="VYO11_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase"
                     /protein_id="HEV1596549.1"
                     /translation="MSYFEQFMQANQAYVALHGQLNLPLKPKTRVAIVTCMDSRLHVA
                     QALGLALGDAHILRNAGGRVTEDMIRSLVISQQQMGTREIVVLHHTDCGAQTFENEPF
                     QEYLKEELGVDVSDQDFLPFQDIEESVREDMQLLIESPLIPDDVIISGAIYNVDTGSM
                     TVVEL"
     gene            2990..3790
                     /locus_tag="VYO11_002058"
     CDS             2990..3790
                     /locus_tag="VYO11_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrsW family intramembrane metalloprotease"
                     /protein_id="HEV1596550.1"
                     /translation="MKKSSILLLCIGLQYETIYYTDGSRSGAEYGLMGVSIFLALFYM
                     IPALYFLFRIGKKWELPKKVLILSLLGGMFLSGWLSSFANTYIHDLLGVLFPDSTFLN
                     AFESAIVAPLVEEPLKLLPLVFVLALIPVRKLKFLFLLGIASGLGFQMIEDIGYIRTD
                     LPEGFDFTISRILERIISGIASHWTFSGLAVVGVYLLYRAYKGQKVGKKQGLIFLGLA
                     LGTHFLFNSPFVELETELPLAIPVVTAIALYGFYHAYCFVEKHNELMT"
     gene            3935..4903
                     /locus_tag="VYO11_002059"
     CDS             3935..4903
                     /locus_tag="VYO11_002059"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEV1596551.1"
                     /translation="MSFSDLKLFALSSNKELAERVAQEIGIELGKSSVRQFSDGEIQV
                     NIEESIRGKHVFILQSTSSPVNDNLLEILIMVDALKRASAESVNVVMPYYGYARQDRK
                     ARAREPITSKLVANMLEVAGVDRLLTIDLHAAQIQGFFDIPVDHLMGAPLIADYFERR
                     GMVGSDYVVVSPDHGGVTRARKLAEFLKTSIAIIDKRRSVDKMNTSEVMNIIGKVEGK
                     TCILIDDMIDTAGTICHAADALAEAGAVEVYASCTHPVLSGPATDNIQKSAIKKLVVL
                     DTIYLPEERLIDKIEQISIAHLLGDAIVRIHEKRPLSPLFDIEKKI"
BASE COUNT         1388 a          888 c         1263 g         1572 t
ORIGIN      
        1 ttttccgaat aaataagata gaataatcta gaataaatga taatagaaaa gagaaaatta
       61 tgaaaattcg tggttttgaa ttggtttcga gttttacaga tgaaaattta ttgcccaagc
      121 gtgagacagc gcatgcggct ggttacgact taaaggttgc tgtgcgtaca gttgttgcgc
      181 caggagagat tgtcttggtt ccgacagggg ttaaggctta tatgcagccg actgaggttc
      241 tctacctcta tgatcgttct tcaaatcctc gtaagaaggg cttggtttta attaactcag
      301 ttggggtcat tgatggagat tattatggaa atcctggaaa tgaagggcat atttttgcgc
      361 agatgaagaa tatcacagac caagaggttg ttcttgaagt tggggagcgt attgtccagg
      421 ctgtttttgc tactttctta attgcagatg gagatgcggc tgatggcgtt cgaactggtg
      481 gatttggatc gacagggcac tagaatgaag attatctttg tacgtcatgg ggagccagat
      541 taccgtgagt tagaggagcg ttcttatata ggatttggga tagatttggc acccttgtct
      601 gagatgggac ggcagcaagt ccagaaattg agcaaaaatc ctttactctc gtcagctgaa
      661 ataatcgtat cttctgcagt cacaagagct ttagaaacgg cttcgtatgt ggtctgtgct
      721 acgggtcttc ctttaaaagt agagccttta ttacatgaat ggcaggtcta taaaacagga
      781 atagaaaact ttgaaacagc tagaagactg tttttagaaa acaaggggga gttgcttcct
      841 aatagtccta ttcaatatga gacagctacg gaaatgaagt ctcggtttct agaatgtatg
      901 tctaagtatc gagaacatca gactgtggta gttgttgctc atcgaatgct catgcgccag
      961 tttgtgccaa atgagaagat tgatttttgc caagtgattg agtgtgagtt agagatatag
     1021 aaagaggttt gtcatcgcaa agaaaaaagc gacatttgta tgtcaaaatt gtgggtataa
     1081 ttcccctaaa tatctgggac gttgccccaa ctgtgggtct tggtcttctt ttgtggaaga
     1141 ggttgaggtt gccgaggtca agaatgcgcg tgtgtccttg acaggtgaga aaaccaagcc
     1201 catgaaacta gctgaggtga cttccatcaa tgtcaatcga accaagacgg agatggagga
     1261 attcaaccgt gtgcttggag gcggagtggt accaggaagt ctcgtcctca tcggtgggga
     1321 tcctgggatt ggaaaatcaa ctcttctcct acaagtctca acccagttgt cccaagtggg
     1381 gacagttctc tatgtcagtg gggaggagtc tgcccagcag attaaactac gtgcagagcg
     1441 cttaggtgat attgatagtg agttttatct ctatgcagag accaatatgc agagtgttcg
     1501 tgcagaagtg gagcgtatcc agccagactt tctcattatt gattccatcc agaccatcat
     1561 gtctcctgag atttcagggg tgcaggggtc tgtttctcag gtacgtgaag tgaccgctga
     1621 actcatgcag ttggccaaga ccaataacat tgccatcttt atcgtaggtc atgtgaccaa
     1681 agaaggaacc ttggctgggc ctcgtatgtt ggagcatatg gtggatacgg tgctttactt
     1741 tgaaggggag cgtcaccaca cctttcgtat tttgagagcg gtcaaaaatc gttttggttc
     1801 cactaatgag attgggattt ttgagatgca gtcgggcggc ttggttgagg tactcaatcc
     1861 gagtcaagtt ttcctagaag agcgtttgga tggggcgact ggttcctcca tcgttgtaac
     1921 catggaaggg acgcgtccga ttttggcgga ggttcaggct ttggtaacac cgaccatgtt
     1981 tggaaatgcc aagcgtacta cgacaggact tgattttaac cgtgctagct tgattatggc
     2041 tgttttggaa aaacgggcag ggcttctctt gcaaaatcag gatgcctatc tcaaatctgc
     2101 tggtggtgtt aaattggatg aacctgcgat tgacttggct gttgcagttg ctattgcttc
     2161 gagctacaaa gacaagccaa ctaatcctca ggaatgtttt gtcggagaac tgggcttgac
     2221 aggagagatt cggcgcgtga atcgtattga gcaacgcatc aacgaagctg ctaaactggg
     2281 ctttactaag atttatgtac ctaagaattc cttgacagga atcactctgc ctaaggaaat
     2341 tcaggtcatt ggcgtggcaa cgattcagga agttttgaaa aaggtctttg cataatccgt
     2401 gacaaattct cttaaaaatg ataagatagg agaaatattt gactatcaaa ttttcaagga
     2461 gggaatcgtg tcgtattttg aacagtttat gcaagctaat caggcttatg ttgccctaca
     2521 tgggcagtta aatctgccac ttaaacccaa aacaagagta gctattgtga cctgtatgga
     2581 ctctcgtctg cacgttgcgc aagctctggg cttggcactt ggggatgctc atatcttgcg
     2641 gaatgcaggt ggtcgagtga ctgaagacat gattcgttcg ctagttattt cccagcaaca
     2701 aatggggaca agagagattg tggtattgca ccatacagac tgtggtgctc agacctttga
     2761 aaatgaacct tttcaggagt atttaaaaga ggaattaggt gtagatgtgt cagaccagga
     2821 cttcttgccc ttccaagata tagaagagag tgtacgcgag gatatgcaac tgcttatcga
     2881 gtctccccta ataccagacg atgtcattat ctctggtgct atttacaatg ttgatacagg
     2941 aagtatgaca gtcgtagaat tataaatact tcatttagaa agaaagtgta tgaagaaaag
     3001 cagtatttta ttgctatgta ttggtttaca gtatgaaacc atctactata cggacggttc
     3061 gaggtcaggt gcggaatatg gactaatggg agtttctatc tttctagctc tcttttacat
     3121 gattccggct ctttattttc tcttccgtat tgggaaaaaa tgggaattgc caaagaaggt
     3181 tttgattctg tctttattgg gagggatgtt cctttcaggc tggttgtcta gttttgctaa
     3241 tacttatatc catgatttac tgggggttct tttcccagat agtacatttt taaatgcctt
     3301 tgaaagtgct attgtggctc ctttggtaga agaacccttg aaattattgc cacttgtttt
     3361 tgttttggct ttgattcctg tgcgaaaatt aaaatttttg tttttacttg gaattgcctc
     3421 cggtttggga ttccaaatga ttgaggatat tggttatatt cgtacggatt tgccagaggg
     3481 ctttgacttt actatttcgc gaattttaga gcgtatcatc tcaggaattg cctctcactg
     3541 gactttttca ggtctagctg tagtaggtgt ttacttgctt tacagagcct ataaaggaca
     3601 gaaggttggc aagaaacagg gccttatttt tctaggttta gccttgggaa ctcacttctt
     3661 gtttaactct ccttttgtgg agttggaaac agagttgcct ttagcgattc cagtggttac
     3721 ggctattgct ctctatggtt tttatcatgc ttattgcttt gttgagaaac acaatgagtt
     3781 gatgacctag aatatttttc aaaagaatga tgcaagggta caaatatggt gcccttcttt
     3841 tatttttgat tgaaaaatag tgcaaaaagc gctacaatgg tagatggaaa atcttgtgaa
     3901 aagcacaagt tatacatata taccggagga aatcatgtct ttttctgatt taaagctgtt
     3961 tgccctttct tctaataaag aattggcaga acgtgtggcg caggagattg ggatagagtt
     4021 ggggaaatca agtgttcgcc aattttcaga tggagagatt caggtcaaca ttgaagaatc
     4081 aatccgtggg aaacacgtct ttatcctaca atcaactagt tcgcctgtaa atgacaatct
     4141 gcttgaaatt ttgattatgg tagatgcttt gaagcgtgcg agtgcagaat ctgtcaatgt
     4201 tgtcatgcct tactatgggt atgcacgtca ggatagaaag gcgagagcgc gtgagccaat
     4261 cacttcaaaa cttgtcgcaa atatgcttga agtagctgga gtggatcgtt tattgaccat
     4321 cgacttgcat gctgcgcaaa ttcaaggatt ctttgatatt cctgtggatc atttgatggg
     4381 tgctcctctg attgcagatt attttgagcg tcgtggtatg gttggttctg actatgtggt
     4441 tgtcagcccg gaccatggag gggtgactcg tgctcgtaag ttggcagaat ttttgaaaac
     4501 atctatcgct attattgata aacgtcgtag cgttgataag atgaatacta gtgaagttat
     4561 gaacatcatc ggtaaggttg aaggcaagac ttgtatcttg attgatgata tgattgatac
     4621 cgctggaacg atttgtcatg cggcagatgc tcttgcggaa gctggtgctg ttgaagtcta
     4681 tgcaagctgt acgcacccag ttctttctgg tcctgctacg gacaatatcc aaaaatcagc
     4741 tattaagaaa ttggttgttt tggataccat ctatcttcca gaagagcgtt tgattgataa
     4801 gattgagcag atttcaatcg ctcatctcct aggggatgct atcgtacgta ttcatgaaaa
     4861 acgaccactt tctccacttt tcgatattga gaaaaaaatt taatgaccaa gcctgagatg
     4921 attctcaggt tttttcgtct tttttccgaa taaatagata gtagcggtga atctagtaaa
     4981 gctagattta aaactgtgat ataataaaaa gagaagaaat atgactgtac gtcatcagaa
     5041 gtttcagcga ccatcatttt tgaacagtga tagcacttga atcgacgctt tctaaggaga
     5101 attctagtag g
//
LOCUS       DAVLXH010000088         5069 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00028199
            SAMN33607166-rid17955573.denovo.089, whole genome shotgun sequence.
ACCESSION   DAVLXH010000088 DAVLXH010000000
VERSION     DAVLXH010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607166
            Sequence Read Archive: SRR23725544
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5069)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5069)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721421.1
            Genome Coverage       :: 115x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:42:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,210
            CDSs (total)                      :: 2,161
            Genes (coding)                    :: 2,023
            CDSs (with protein)               :: 2,023
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 73 of 138
            Pseudo Genes (incomplete)         :: 60 of 138
            Pseudo Genes (internal stop)      :: 40 of 138
            Pseudo Genes (multiple problems)  :: 31 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5069
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607166-rid17955573.denovo.089"
                     /strain="AUSMDU00028199"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1349"
     gene            100..1593
                     /locus_tag="VYO11_002060"
     CDS             100..1593
                     /locus_tag="VYO11_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HEV1596552.1"
                     /translation="MITGELKNKIDQLWEILWTEGNANPLTNIEQLTYLLFMKDLDSV
                     ELGRESDAEFLGIPYEGVFPKDKPEYRWSTFKNIGDAQEVYRLMTQEIFPFIKNLKGD
                     TDDTAFSRYMREAIFQINKPATLQKAISILDVFPTRGLDVDFDNDKQSITDIGDIYEY
                     LLSKLSTAGKNGQFRTPRHIIDMMVELMQPTIKDIISDPAMGSAGFLVSASRYLKRKK
                     DEWETNTDNINHFHNQMFHGNDTDTTMLRLGAMNMMLHGVENPQISYLDSLSQDNEEA
                     DKYTLVLANPPFKGSLDYNSTSNDLLATVKTKKTELLFLSLFLRTLKPGGRAAVIVPD
                     GVLFGSSKAHKGIRQEIVENHKLDAVISMPSGVFKPYAGVSTAILIFTKTGNGGTDKV
                     WFYDMKADGLSLDDKRQPISDNDIPDIIERFHHLEKEAERQRTDQSFFVPVAEIKEND
                     YDLSINKYKEIEYEKVEYEPTEVILKKINDLEKEIQAGLAELEKLLK"
     gene            1606..2148
                     /locus_tag="VYO11_002061"
     CDS             1606..2148
                     /locus_tag="VYO11_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEV1596553.1"
                     /translation="MKKVKLGEVCEILSGYAFKSSQFNDNKIGLPLIRIRDVERGFSD
                     TYFEGTYPEEYLIKNGDLLITMDGSFILKKWEGDLALLNQRVCKIKITDKSVDEGYIS
                     WLIPKFLKEIEDKTPFVTVKHLSVAKIKDISFVLPNKLEQKLIAKKLNTISQIYDFRK
                     IQSEKFNELVKSRYSEEVVA"
     gene            2145..2732
                     /locus_tag="VYO11_002062"
     CDS             2145..2732
                     /locus_tag="VYO11_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000756206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEV1596554.1"
                     /translation="MKKVKLGQVATFINGYAFKPQDWSSEGKEIIRIQNLTKTSKGIN
                     YYSGTIDKKYIVEAGDILISWSGTLGVFQWCGRSAVLNQHIFKVVFDKIDIDKSYFKY
                     VVEKGLQDAVKHTHGSTMKHLTKKYFDNIMVSYTNLGEQQRIASELDLLSKLILRRQE
                     QLEELNLLVKSQLAIQKSLEELETLKKSLMQEYFG"
     gene            2792..3028
                     /locus_tag="VYO11_002063"
     CDS             2792..3028
                     /locus_tag="VYO11_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000260605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HEV1596555.1"
                     /translation="MVVKTRKQGNSITITIPSEFNIPSGVKYEAKLLPSGEIIFTPEE
                     LGQQVSYVSDDAFDLNLDKIFDEYDDVFKALVEK"
     gene            3025..3438
                     /locus_tag="VYO11_002064"
     CDS             3025..3438
                     /locus_tag="VYO11_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000158364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HEV1596556.1"
                     /translation="MTIYLTEKQIEKINALAIQRYSPNEKIQTVSPSALNMIVNLPEQ
                     FVFGKPLYPTIFDKATILFVQLIKKHVFANANKRTAFFVLVKFLQLNGYRFSITVEEA
                     VKMCVTIAVEALTDEKMTSYSKWISEHSVREKVKK"
     gene            3556..4521
                     /locus_tag="VYO11_002065"
     CDS             3556..4521
                     /locus_tag="VYO11_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEV1596557.1"
                     /translation="MESKVTIIMQEMLPLLNNEQLLALRESLEHHLVDGKKQQKYSNN
                     NLLQLFITAKQVEGCSSKTIRYYQRTIENLFNAIKESVTQLTTDDLRSYLANYQSEKD
                     CSKANLDNIRRILSSFFAWLEQEEYIIKNPIRRIKKIKTEQNVKETYTDEHLEIMRDN
                     CENLRDLAIIDLLASTGMRVGELVQLNRSDIDFENRECVVFGKGKKERPVYFDARTKI
                     HLRNYLNDRKDSHPALFVTLVGKVQRLGIAGVEIRLRKLGDKLGIQKVHPHKFRRTLA
                     TKAIDKGMPIEQVQKLLGHSKIDTTLAYAMVNQNNVKHSHQKFIS"
     gene            4487..>5069
                     /locus_tag="VYO11_002066"
     CDS             4487..>5069
                     /locus_tag="VYO11_002066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001852328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEV1596558.1"
                     /translation="MSSIHTKNSSLKSKSRFNEMFGENKIFESIDNLFDIIDGDRGKN
                     YPKSDELFSEEYCLFLNTKNVTKNGFSFDTKQFITKTKDKLLRKGKLERYDIVLTTRG
                     TVGNVAYYDELIKYKHLRINSGMVILRPKTPNLNQKFIIHVLRNNNYSRVISGSAQPQ
                     LPITKLKKILLPLPPLALQNEFADFVAQVDKSQF"
BASE COUNT         1821 a          741 c          981 g         1526 t
ORIGIN      
        1 tattcaggtg acgcatagat atagttaatt gaagctttgt ttgaaatctg ataaaataat
       61 gatattacta agttttaaaa actaaagaaa agggaagata tgattacagg cgaattaaaa
      121 aataaaatcg accagctgtg ggaaattctt tggacagaag gaaacgcaaa tcctttaaca
      181 aatattgaac agttgactta tctcttattt atgaaagatt tggatagtgt cgagcttgga
      241 cgtgaaagtg atgctgaatt tctagggatt ccttatgagg gagtttttcc aaaagataaa
      301 cctgaatacc gttggtcaac ttttaaaaat ataggagatg ctcaggaagt ttatcgttta
      361 atgactcagg agatttttcc gtttattaaa aatctcaagg gggatacaga tgatacagcc
      421 ttttcacgat atatgcgaga agctattttt caaataaata aacctgctac gcttcaaaag
      481 gcaatttcta tcttagatgt ttttccaact aggggattag atgtagattt tgataatgac
      541 aaacaaagta ttactgatat cggagatatc tatgaatatc tgttatcaaa attgtcgacc
      601 gcaggtaaaa atggacagtt ccgtacacct cgtcacatca tcgatatgat ggttgagttg
      661 atgcaaccga ctatcaaaga tatcatctca gatcccgcta tgggttctgc tggcttctta
      721 gtatctgcta gccgttactt aaagcgtaag aaagatgaat gggaaaccaa tacagataat
      781 atcaatcatt ttcataatca gatgtttcat ggaaatgata cggatacgac tatgttgaga
      841 cttggggcga tgaacatgat gctacatgga gtagaaaatc cacaaatcag ttaccttgac
      901 tcgctgtctc aagataatga agaagccgat aaatatactt tggttttagc aaatcctcct
      961 tttaagggct cacttgacta caattcaacc tctaatgacc ttcttgcaac cgtaaaaacc
     1021 aaaaaaacag aattactctt tctttctctt ttcttgcgaa ctttaaaacc aggtggacga
     1081 gcagcagtta tcgtacctga tggtgtcctt tttggttcgt ctaaagctca taaaggaatt
     1141 cgtcaggaaa ttgtagagaa tcataagctt gatgctgtaa tctcaatgcc tagtggtgtg
     1201 ttcaagcctt atgctggagt ttcaactgct attctcatct ttacaaaaac tggtaatggt
     1261 ggtactgaca aagtctggtt ttacgatatg aaagcggatg gtttaagttt ggatgataag
     1321 cgacaaccga ttagcgacaa tgatattcca gatattatcg aacgctttca tcatcttgaa
     1381 aaagaagcag aacgtcagag aacggatcaa tctttctttg ttccagttgc tgagataaag
     1441 gaaaatgatt atgatttgtc tatcaataaa tataaagaga ttgagtatga aaaagttgag
     1501 tatgaaccaa cagaagtcat attaaagaaa atcaatgatt tagaaaaaga aattcaagct
     1561 ggcttggctg aattggaaaa attactcaag tagggaggtg gctgtatgaa aaaagtgaag
     1621 ttgggggaag tttgtgagat tttatctggt tacgctttta aatcatcaca atttaatgat
     1681 aacaaaattg gtctcccctt aatacgaatt cgagatgtag aaagaggttt ttctgatacc
     1741 tactttgaag gaacttatcc cgaagaatat cttattaaaa atggagactt attgattaca
     1801 atggatggca gttttatatt gaaaaaatgg gagggggatt tagcgctact taatcaacgt
     1861 gtctgtaaaa ttaaaattac ggataaaagt gtagatgaag gttatatatc ttggttgatt
     1921 cctaaatttt taaaagaaat tgaagataag accccttttg ttacagtgaa acatctttca
     1981 gtagctaaaa taaaagatat ctcatttgta ttgcctaata aactagaaca aaagctaatt
     2041 gcaaaaaaac taaatacgat aagtcaaatt tatgattttc gtaaaattca atcagaaaaa
     2101 tttaacgagc tcgtcaaatc ccgatattcc gaggaggtgg ttgcatgaag aaagtgaaat
     2161 tagggcaagt ggctactttt atcaatggct atgcttttaa acctcaagat tggtcatctg
     2221 aagggaaaga gattatcaga atacagaatc tgactaaaac ttcaaaaggg ataaattatt
     2281 attcgggtac gattgataaa aaatacattg ttgaagctgg tgatattctt atttcgtggt
     2341 cgggtacatt aggggttttt cagtggtgtg gaagatccgc agtgttaaat cagcacattt
     2401 ttaaagtggt ttttgataag atagatatag ataaatcgta ttttaaatat gttgttgaaa
     2461 aaggtttaca agatgctgta aaacatactc atggttccac aatgaaacat ttaactaaaa
     2521 aatattttga taatattatg gtttcatata caaatttggg agagcaacaa agaattgcaa
     2581 gtgagctgga tttgttaagc aagctgattt taaggagaca agaacaactt gaagagctta
     2641 atctacttgt aaaatcacaa ttggcaatcc aaaaatctct ggaagaactt gaaactttga
     2701 agaaatctct gatgcaggag tattttggct gatattctgc cattgtaatt acggtaatga
     2761 tttgttataa tacttcaaag gaggaaatca gatggtagta aaaacaagaa aacaaggaaa
     2821 ttcaatcacc attacgattc caagtgaatt taatattcca agtggtgtta aatacgaagc
     2881 gaaattgtta ccaagtggtg agattatctt tactcctgaa gaattggggc agcaggtttc
     2941 ttatgtatct gatgatgcct ttgacttaaa tttagataaa atatttgacg aatacgacga
     3001 tgttttcaaa gctttggtgg aaaaatgaca atctatttga cagaaaagca aattgaaaaa
     3061 ataaatgctt tagcaattca acggtattct ccaaatgaga aaattcaaac agttagtcct
     3121 tctgccttaa atatgattgt gaacttacca gaacaatttg tctttgggaa gcctctttat
     3181 ccaacaattt ttgataaagc aacgatacta tttgtccaat tgataaagaa gcatgttttt
     3241 gctaatgcta ataaaagaac tgctttcttc gttttggtca aatttttaca attaaacggc
     3301 tatcgttttt ctataacggt agaagaagca gtaaaaatgt gtgtaaccat cgcagtagaa
     3361 gctttaactg atgaaaaaat gacaagctac tccaaatgga tttctgaaca ttctgttaga
     3421 gaaaaggtca aaaagtaacc tagtatgctg gatttgaatg agcacaagaa aataaatgaa
     3481 cagacaatat tagaattctg taatgcagaa actgatattg tctcttttta ttgatgaata
     3541 agaaagtgag aaattatgga atcaaaagtt acaattatca tgcaagaaat gttacctctt
     3601 ttaaataatg aacaattact agcgttgaga gagagtttag aacatcatct agtagacgga
     3661 aaaaagcagc agaagtattc gaataataac ctgttgcaac tatttattac cgccaagcag
     3721 gtagagggct gtagctcaaa aacaattcgt tattaccaga ggacgattga aaacttgttt
     3781 aatgctatta aagagtctgt gacacaactc acaacagatg atttaaggag ttatttagca
     3841 aattaccagt ctgaaaagga ttgtagtaag gcaaatttag acaatattag gcgtatattg
     3901 tcttcttttt ttgcttggct tgagcaagag gaatatatca ttaaaaatcc cattcgacgg
     3961 ataaagaaaa ttaagactga gcaaaatgtg aaggaaactt atactgatga acatttggaa
     4021 attatgcgtg ataactgtga aaatttgaga gatttggcaa taatagacct actagcatcg
     4081 acaggtatgc gtgtagggga gcttgtacag ttgaatcgtt cagatattga ttttgaaaac
     4141 agagagtgtg ttgtctttgg taaaggaaag aaggagagac cagtatattt tgacgctcgg
     4201 acgaaaattc atttaagaaa ttatcttaac gacagaaaag atagtcaccc tgctcttttt
     4261 gtaacgttag ttggaaaagt ccagaggctt ggaattgctg gtgtagagat tcgcttaaga
     4321 aagttaggag acaaactcgg tatacaaaag gttcacccac ataagttcag aagaacttta
     4381 gcgactaagg caattgataa aggtatgcct atcgaacaag tccaaaaact gctaggtcat
     4441 agcaagattg acacaaccct ggcctatgcc atggtcaatc aaaataatgt caagcattca
     4501 caccaaaaat tcatctctta aaagcaaatc ccgatttaac gagatgtttg gggaaaataa
     4561 aatatttgaa agcattgata acttatttga tattatagat ggtgataggg gcaaaaatta
     4621 tcctaaatca gatgagttgt ttagtgagga gtactgttta tttttaaata caaagaatgt
     4681 tactaaaaac ggattttcat tcgatacaaa gcaatttatc actaaaacaa aggataaatt
     4741 acttcgaaaa ggcaaacttg agcgttatga tatagtcttg acaacaagag gtactgttgg
     4801 aaatgtagcg tactacgatg aattaataaa atataaacat ttacgtataa attcaggtat
     4861 ggtaatatta cgtcccaaga caccaaatct aaatcagaaa tttattatcc atgttttaag
     4921 gaataataat tatagtcgag tgatatcagg aagtgctcag cctcagttac caattacaaa
     4981 attaaaaaaa atacttctcc ccctcccccc actagccctc caaaatgagt tcgcagactt
     5041 tgtagcccag gtcgacaaat cacaatttg
//
LOCUS       DAVLXH010000089         4854 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00028199
            SAMN33607166-rid17955573.denovo.090, whole genome shotgun sequence.
ACCESSION   DAVLXH010000089 DAVLXH010000000
VERSION     DAVLXH010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607166
            Sequence Read Archive: SRR23725544
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4854)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4854)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721421.1
            Genome Coverage       :: 115x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:42:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,210
            CDSs (total)                      :: 2,161
            Genes (coding)                    :: 2,023
            CDSs (with protein)               :: 2,023
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 73 of 138
            Pseudo Genes (incomplete)         :: 60 of 138
            Pseudo Genes (internal stop)      :: 40 of 138
            Pseudo Genes (multiple problems)  :: 31 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4854
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607166-rid17955573.denovo.090"
                     /strain="AUSMDU00028199"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1349"
     gene            complement(431..1159)
                     /locus_tag="VYO11_002067"
     CDS             complement(431..1159)
                     /locus_tag="VYO11_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEV1596559.1"
                     /translation="MSTKYLFIYNEIREKILCNKYTMNEQLPDEMTLAKQFACSRMTI
                     KKALDLLVSEGLIFRKRGQGTFVLSRGSSKRKLIVPERDIRGLTKISEDAHSTIDSRI
                     IHFKLEFANEFLAEKLQVALQSPVYNIYRLRIIDGKPYVLEQTYMSTDVIPGITEDIL
                     QKSIYNYIEGKLGLHIASATKILRASSSSENEQHYLQLLPTEPVFEVEQVAYLDNGTP
                     FEYSISRHRYDLFEFNSFALRHSS"
     gene            1317..2726
                     /locus_tag="VYO11_002068"
     CDS             1317..2726
                     /locus_tag="VYO11_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEV1596560.1"
                     /translation="MKKKLVFPNLFWWGAASSGPQTEGQYGKVHENVMDYWFKTHPED
                     FFDNVGPLVASNFFHTYTEDFHLMKEIGVNSFRTSIQWSRLIKNLETGEPDPKGIAFY
                     NAIIEEAKKNQMDLVMNLHHFDLPVELLQKYGGWESKHVVELFVKFAKTAFTCFGDKV
                     HYWTTFNEPMVIPEAGYLYAFHYPNLKGKGKEAVQIIYNLNLASAKVIQLYRSLGLDG
                     KIGIILNLTPAYPRSNSPEDLEASRFTDDFFNKVFLNPAVKGTFPERLVKQLERDGVL
                     WSHTEKELQLMKSNTVDFLGVNYYHPKRVQAQANPEEYQTPWMPDQYFKEYEWPERRM
                     NPYRGWEIFPKAIYDIAMIVKEEYDNIPWFISENGMGVENEARFIGENGVIDDVYRIE
                     FYEEHLRWLHKAIEEGSHCFGYHAWTAFDCWSWNNAYKNRYGFISVDLETQKRTIKSS
                     GRWYRKVSDNNGFEVEIEE"
     gene            2744..4039
                     /locus_tag="VYO11_002069"
     CDS             2744..4039
                     /locus_tag="VYO11_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000798148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEV1596561.1"
                     /translation="MKNSKFIDQFATFAGKLGNQIHLKTLRDAFVTVMPLYILAGLIV
                     LLNNTVFKWIFQGDTLTRFQYWGITIANGTLSISGMIIAVMVGYFLAKNRDFENPLAA
                     SMLSLVSLIVMMPNTVSVVPDGAKDAVNISGVLSFNNTGTGAMFAGVIVAIIATELFI
                     ELSNVKALQMNLGENIPPAVSRSFSVLLPVMTVISLFGVVSALLFNITGMNLISIITI
                     FIQEPIRHIGTSLIGVIIIYSLGNMLWLFGIHQAVIYSAILEPLLLINITENITAANN
                     GQAIPHIINLSQIQTFALMGGSGSTLCLLIATFLVSRNAVSKNVAKLSFGPGIFNINE
                     PVLFGYPIVYNISLAIPFITVPVLGILISYLATVTGFMSPAFIQVPWTTPVFLNAWLA
                     TAGDVRAVLVQFIIFALGVLLYIPFIKVNDKVVEQEMEG"
     gene            4044..4352
                     /locus_tag="VYO11_002070"
     CDS             4044..4352
                     /locus_tag="VYO11_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV1596562.1"
                     /translation="MKQILLVCNAGMSTSMLVKKMQQSATERGIEISIQAKSMTEAKK
                     NIHEADVILIGPQIRYELLAVKEIAGNIPVDTIDMRDYGMMNGAKVLEQALAWIGEIR
                     "
     gene            4349..4657
                     /locus_tag="VYO11_002071"
     CDS             4349..4657
                     /locus_tag="VYO11_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000134125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEV1596563.1"
                     /translation="MTEEMEYICFQLIANSGAAKSSFIEAIQLAKAGNLKEAKIKVEE
                     AEDSLVEAHKIHSNLIQKEATGEKIGFSLLFMHAEDQMASTEIIQLLSKEFIDLYQNK
                     "
BASE COUNT         1645 a          814 c          897 g         1498 t
ORIGIN      
        1 ataaaatttt tttaaatgat tatgattcag aatttattta atatattaaa agaagatatg
       61 aacaaataaa ttgggagatt gaaattcatt tctagcaatt tgttagaagt cacagtctac
      121 tattctaacc tcagtatact atatgtgtta caagaaaaga ctcaaaaact tctcgtcagt
      181 gtaagaatgt ttgaaacact atttaaaact aaataactat aagaagtaga tcaggtgaac
      241 aatttcagta cctactctat aagctatacg aagatatttt tcaacatgat ggataaaacg
      301 atcactcttt taaagccatc ttatttagaa aagagaaacc atttaagcat agatgggacc
      361 ttcttgccct gttttaaatt tttcttaaac tagagtctgt aaaagattgg cttcattttc
      421 acattttctc ctaggaggaa tgtcgtaatg caaaagaatt aaattcaaat aaatcatagc
      481 gatgacgact aatcgagtac tcaaacggag ttccgttatc caaataagcc acttgttcta
      541 cttcaaatac cggttccgtt ggaaggagct gcaagtaatg ttgctcattt tctgaactag
      601 aagaagctcg caagattttt gtagcactgg caatatgcaa tcctaacttt ccttcaatgt
      661 aattgtaaat cgatttttgt aaaatatctt cagtaatacc tggaataaca tcggtactca
      721 tataagtttg ttccagaaca taaggtttac cgtcaataat acgcaggcgg taaatattat
      781 aaactggact ctgcaaagcg acctgtagtt tttctgctaa aaattcattt gcaaattcta
      841 atttgaagtg aataatcctc gagtcaattg tagaatgagc atcttcagat atttttgtca
      901 gtccccggat atctctttct ggaacgatta attttctttt tgagctgcca cgagagagaa
      961 caaaggttcc ctgcccacgt tttctaaaaa ttaagccctc agaaactaac aagtctaaag
     1021 cttttttgat cgtcattcga ctacaggcaa actgtttagc taatgtcatt tcatcaggca
     1081 attgttcgtt catggtatat ttattacaaa gaatcttttc acgaatctca ttgtaaataa
     1141 ataaatattt tgtactcatt taatctggtt ctctctataa tattctaata gtagtataac
     1201 aaagttcaag aaatgaggca aacacaagat atgtataaac aatttttaaa aatgtctaga
     1261 caaattttaa aattatgcta tactttatgt atagaataat agaaaggagg ttgagcatga
     1321 aaaaaaagtt agtatttcct aatctgtttt ggtggggggc tgcttctagc ggacctcaga
     1381 cagaaggtca atatggaaaa gtacatgaaa atgtgatgga ctactggttc aaaacgcatc
     1441 cagaagattt tttcgataat gtcggacctc ttgtagccag taactttttt catacttaca
     1501 ccgaagattt ccacttgatg aaggaaattg gagttaattc tttccgcact tccatccaat
     1561 ggagtcgact catcaagaat ttagagacag gtgagcctga tccaaaaggt attgctttct
     1621 acaatgccat cattgaagaa gctaaaaaga accagatgga tcttgtgatg aatttacatc
     1681 attttgattt accagtggaa cttcttcaaa aatacggtgg ttgggaaagc aaacatgtag
     1741 tggagttatt cgtgaagttt gccaagactg ctttcacatg ctttggagat aaggttcatt
     1801 actggacaac tttcaatgag ccaatggtca ttccagaagc aggatactta tatgctttcc
     1861 attatccaaa tctaaaagga aagggaaaag aggccgtaca aatcatctat aatctaaacc
     1921 ttgctagtgc aaaagtgatt caactatatc gctcattagg acttgatgga aagattggga
     1981 ttattttaaa cttgacacct gcttatccaa gaagtaattc tccagaagac ttagaagcaa
     2041 gtcgatttac agatgacttc tttaacaaag tcttcttgaa tccagctgtt aaaggaactt
     2101 tcccagaaag attggtaaaa cagctagaga gagatggcgt gttatggagt cataccgaaa
     2161 aagagcttca actgatgaaa tcaaatacgg ttgattttct tggagtaaac tactaccatc
     2221 caaaacgtgt tcaagcacaa gcaaatcctg aggaatatca gacgccctgg atgccagacc
     2281 aatacttcaa agagtatgaa tggccggagc gtcgcatgaa tccatatcgt ggttgggaaa
     2341 tttttccgaa agccatttat gatattgcta tgattgtgaa ggaagaatat gataatattc
     2401 catggtttat cagtgaaaac ggaatgggtg ttgaaaacga agcacggttt atcggtgaaa
     2461 atggagttat cgatgacgtg tatcgtattg aattttatga agaacattta agatggctac
     2521 ataaagccat tgaagaggga agtcactgtt ttggatacca cgcttggacc gcatttgatt
     2581 gctggtcttg gaataatgca tataagaatc gttacggatt tatctccgtt gatttagaaa
     2641 cgcaaaagag aaccatcaag agctcaggaa gatggtatcg caaagtaagt gacaataacg
     2701 gttttgaagt agaaattgag gagtaaagag aggagatatt cagatgaaaa actcaaaatt
     2761 tatagatcaa tttgccacct ttgctggtaa actagggaac caaattcatt taaaaaccct
     2821 aagagatgca ttcgtaacag taatgccatt atatattttg gcaggtttaa tcgttctttt
     2881 gaacaacacg gtatttaagt ggattttcca aggggataca ttaacaagat tccaatattg
     2941 gggaataaca attgcaaacg gtactttaag tatttcaggt atgattattg ctgtaatggt
     3001 tggttatttc ttagctaaaa acagagattt cgaaaacccg ttagcagcat caatgctatc
     3061 attagtttct ttaattgtga tgatgccaaa tacagtttct gtagttcctg acggagcaaa
     3121 agatgcggta aacatttcag gtgttctttc attcaacaac acaggtacag gcgcaatgtt
     3181 cgccggggtt atcgtagcga ttattgcaac agaattattc attgaattat caaacgttaa
     3241 agctttacaa atgaaccttg gtgaaaatat tccaccagct gttagtagat catttagcgt
     3301 attacttcca gtcatgaccg tcatctcctt atttggggtt gtttcagcat tattattcaa
     3361 tataactgga atgaacttaa tctcaatcat tacaatcttt attcaagaac caattcgtca
     3421 tattggtaca agcttaatcg gggtcattat tatttactct ttaggaaata tgttatggct
     3481 atttggtatt caccaagcag ttatttacag tgccatccta gaaccattac tattaattaa
     3541 cattactgaa aacatcactg cagcaaataa tggacaagcc attccacaca tcatcaacct
     3601 atcacaaata caaacattcg ctttaatggg tggtagtgga tctacattat gtttattaat
     3661 agcaacattc ttagtgagtc gcaatgctgt ctctaaaaac gtggctaaat tatcttttgg
     3721 acctggtatc ttcaatatca atgaaccagt attattcggt tacccaatcg tttataacat
     3781 ttcattagct attccattta tcacagttcc agtccttggt attttaatca gctacttagc
     3841 aacagttaca ggattcatga gtcctgcatt tatacaagtt ccttggacta caccagtatt
     3901 cttaaatgca tggttagcaa cagcagggga cgtgagagca gttctagttc aattcatcat
     3961 ctttgcactt ggagttcttc tatacattcc atttatcaaa gttaatgaca aagttgttga
     4021 gcaagaaatg gaaggttaag attatgaaac aaattttatt agtatgtaat gcgggaatgt
     4081 cgacaagtat gcttgttaaa aaaatgcaac aaagtgcgac tgaacgtggg attgaaattt
     4141 ctatccaagc aaaatcaatg acagaagcta aaaagaatat ccatgaagca gatgtcattc
     4201 taattgggcc acaaattcgt tatgagttac ttgctgtgaa agaaattgca ggaaatatcc
     4261 ctgtagatac cattgatatg cgggattacg gaatgatgaa tggagcaaaa gttctggaac
     4321 aagcacttgc atggatagga gaaataagat gacagaagaa atggaatata tctgttttca
     4381 gctcattgcc aatagtggag cagccaaatc atcctttatt gaagccatcc aactagctaa
     4441 ggcaggaaat ttaaaagaag cgaaaattaa agttgaagaa gcggaagact ccttagtaga
     4501 agcgcacaag attcactcta atctcataca aaaagaagct actggagaaa aaataggatt
     4561 ctccttgcta tttatgcatg cagaagacca aatggcttca acagagatta ttcagttgct
     4621 atctaaagaa ttcatcgatc tctatcaaaa taaataggaa cactgtcgtt cccatctgtc
     4681 tttattaatg acggctacat tgtaggaacc tccaaaagtt ggacaaaatg attgaaagga
     4741 ttggatcctg cattacacaa gatccaatcc ttttctttta ctctagtttt tataatgtgt
     4801 tgaatttaga atagtccact gcagtttcta aaaaattgct ggaaatagat gtta
//
LOCUS       DAVLXH010000090         4645 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00028199
            SAMN33607166-rid17955573.denovo.091, whole genome shotgun sequence.
ACCESSION   DAVLXH010000090 DAVLXH010000000
VERSION     DAVLXH010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607166
            Sequence Read Archive: SRR23725544
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4645)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4645)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721421.1
            Genome Coverage       :: 115x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:42:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,210
            CDSs (total)                      :: 2,161
            Genes (coding)                    :: 2,023
            CDSs (with protein)               :: 2,023
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 73 of 138
            Pseudo Genes (incomplete)         :: 60 of 138
            Pseudo Genes (internal stop)      :: 40 of 138
            Pseudo Genes (multiple problems)  :: 31 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4645
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607166-rid17955573.denovo.091"
                     /strain="AUSMDU00028199"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1349"
     gene            <1..1323
                     /locus_tag="VYO11_002072"
     rRNA            <1..1323
                     /locus_tag="VYO11_002072"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
     gene            1375..1447
                     /locus_tag="VYO11_002073"
     tRNA            1375..1447
                     /locus_tag="VYO11_002073"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1408..1410,aa:Ala,seq:tgc)
     gene            1572..4473
                     /locus_tag="VYO11_002074"
     rRNA            1572..4473
                     /locus_tag="VYO11_002074"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
     gene            4550..>4645
                     /gene="rrf"
                     /locus_tag="VYO11_002075"
     rRNA            4550..>4645
                     /gene="rrf"
                     /locus_tag="VYO11_002075"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT         1286 a          957 c         1378 g         1024 t
ORIGIN      
        1 actaccagat ggacctgcgt tgtattagct agttggtggg gtaacggctc accaaggcga
       61 cgatacatag ccgacctgag agggtgatcg gccacactgg gactgagaca cggcccagac
      121 tcctacggga ggcagcagta gggaatcttc ggcaatggac ggaagtctga ccgagcaacg
      181 ccgcgtgagt gaagaaggtt ttcggatcgt aaagctctgt tgtaagagaa gaacgagtgt
      241 gagagtggaa agttcacact gtgacggtat cttaccagaa agggacggct aactacgtgc
      301 cagcagccgc ggtaatacgt aggtcccgag cgttgtccgg atttattggg cgtaaagcga
      361 gcgcaggcgg ttagataagt ctgaagttaa aggctgtggc ttaaccatag taggctttgg
      421 aaactgttta acttgagtgc aagaggggag agtggaattc catgtgtagc ggtgaaatgc
      481 gtagatatat ggaggaacac cggtggcgaa agcggctctc tggcttgtaa ctgacgctga
      541 ggctcgaaag cgtggggagc aaacaggatt agataccctg gtagtccacg ctgtaaacga
      601 tgagtgctag gtgttagacc ctttccgggg tttagtgccg tagctaacgc attaagcact
      661 ccgcctgggg agtacgaccg caaggttgaa actcaaagga attgacgggg gcccgcacaa
      721 gcggtggagc atgtggttta attcgaagca acgcgaagaa ccttaccagg tcttgacatc
      781 cctctgaccg ctctagagat agagttttcc ttcgggacag aggtgacagg tggtgcatgg
      841 ttgtcgtcag ctcgtgtcgt gagatgttgg gttaagtccc gcaacgagcg caacccctat
      901 tgttagttgc catcatttag ttgggcactc tagcgagact gccggtaata aaccggagga
      961 aggtggggat gacgtcaaat catcatgccc cttatgacct gggctacaca cgtgctacaa
     1021 tggctggtac aacgagtcgc aagccggtga cggcaagcta atctcttaaa gccagtctca
     1081 gttcggattg taggctgcaa ctcgcctaca tgaagtcgga atcgctagta atcgcggatc
     1141 agcacgccgc ggtgaatacg ttcccgggcc ttgtacacac cgcccgtcac accacgagag
     1201 tttgtaacac ccgaagtcgg tgaggtaacc gtaaggagcc agccgcctaa ggtgggatag
     1261 atgattgggg tgaagtcgta acaaggtagc cgtatcggaa ggtgcggctg gatcacctcc
     1321 tttctaagga taaggaactg cgcattggtc ttgtttagtc ttgagaggtc ttgtggggcc
     1381 ttagctcagc tgggagagcg cctgctttgc acgcaggagg tcagcggttc gatcccgcta
     1441 ggctccattg gtgagagatc accaagtaat gcacattgaa aattgaatat ctatatcaaa
     1501 tagtaacaag aaaataaacc gaaaacgctg tagtattaat aagagtttat gactgaaagg
     1561 tcagaaaata aggttaagtt aataagggcg cacggtggat gccttggcac taggagccga
     1621 cgaaggacgt gacaaacgac gatatgcctt gggtagctgt aagtaagcga tgatccaggg
     1681 atttccgaat gggggaaccc aacaggtaat acctgttacc cacatctgtt aaggatgtga
     1741 ggaggaagac gcagtgaact gaaacatcta agtagctgca ggaagagaaa gcaaaagcga
     1801 ttgccttagt agcggcgagc gaaacggcag aagggcaaac cgaagagttt actcttcggg
     1861 gttgtaggac tgcaatgtgg actcaaagat tatagaagaa tgatttggga agatcagcca
     1921 aagagagtaa tagcctcgta tttaaaatag tctttgtact tagcagtatc ctgagtacgg
     1981 cgggacacgt gaaatcccgt cggaatctgg gaggaccatc tcccaaccct aaatactccc
     2041 tagtgaccga tagtgaacca gtaccgtgag ggaaaggtga aaagcacccc gggaggggag
     2101 tgaaatagaa cctgaaaccg tgtgcctaca acaagttcga gcccgttaat gggtgagagc
     2161 gtgccttttg tagaatgaac cggcgagtta cgttatgatg cgaggttaag ttgaagagac
     2221 ggagccgtag ggaaaccgag tctgaatagg gcgccttagt atcatgacgt agacccgaaa
     2281 ccatgtgacc tacccatgag caggttgaag gtgcggtaag acgcactgga ggaccgaacc
     2341 agggcacgtt gaaaagtgct tggatgactt gtgggtagcg gagaaattcc aaacgaactt
     2401 ggagatagct ggttctctcc gaaatagctt tagggctagc gtcgacatta gagattcttg
     2461 gaggtagagc actgtttggg tgaggggtcc atcccggatt accaatctca gataaactcc
     2521 gaatgccaat gaattatggt cggcagtcag actgcgagtg ctaagatccg tagtcgaaag
     2581 ggaaacagcc cagaccacca gctaaggtcc caaaataatt gttaagtgga aaaggatgtg
     2641 gggttgcaca gacaactagg atgttagctt agaagcagct attcattcaa agagtgcgta
     2701 atagctcact agtcgagtga ccctgcgccg aaaatgtacc ggggctaaaa caatttaccg
     2761 aagctgtgga tacctttata ggtatggtag gagagcgttc tatgtgtgat gaaggtatac
     2821 cgtgaggagt gctggaacgc atagaagtga gaatgccggt atgagtagcg aaagacaggt
     2881 gagaatcctg tccaccgtaa gactaaggtt tccaggggaa ggctcgtccg ccctgggtta
     2941 gtcgggacct aaggagagac cgaaaggtgt atccgatgga caacaggttg atattcctgt
     3001 actagagtat gtagtgatgg agggacgcag taggctaact aaagcagacg attggaagag
     3061 tctgtctaag cagtgaggtg tgatatgagt caaatgctta tatctgtaac attgagctgt
     3121 gatggggagc gaagtttagt agcgaagtta gtgacgtcac actgccaaga aaagcttcta
     3181 gcgtttaaac atactctacc cgtaccgcaa accgacacag gtagtcgagg cgagtagcct
     3241 caggtgagcg agagaactct cgttaaggaa ctcggcaaaa tgaccccgta acttcgggag
     3301 aaggggtgct gactttaagt cagccgcagt gaataggccc aagcaactgt ttatcaaaaa
     3361 cacagctctc tgctaaatcg taagatgatg tatagggggt gacgcctgcc cggtgctgga
     3421 aggttaagag gagtgcttag cgtaagcgaa ggtatgaatt gaagccccag taaacggcgg
     3481 ccgtaactat aacggtccta aggtagcgaa attccttgtc gggtaagttc cgacccgcac
     3541 gaaaggcgta atgatttggg cactgtctca acgagagact cggtgaaatt ttagtacctg
     3601 tgaagatgca ggttacccgc gacaggacgg aaagacccca tggagcttta ctgcagtttg
     3661 atattgagtg tctgtaccac atgtacagga taggtaggag tctaagagat cgggacgcca
     3721 gtttcgaagg agacgctgtt gggatactac ccttgtgtta tggccactct aacccagata
     3781 ggtgatccct atcggagaca gtgtctgacg ggcagtttga ctggggcggt cgcctcctaa
     3841 aaggtaacgg aggcgcccaa aggttccctc agaatggttg gaaatcattc gcagagtgta
     3901 aaggtataag ggagcttgac tgcgagagct acaactcgag cagggacgaa agtcgggctt
     3961 agtgatccgg tggttccgta tggaagggcc atcgctcaac ggataaaagc taccctgggg
     4021 ataacaggct tatctccccc aagagttcac atcgacgggg aggtttggca cctcgatgtc
     4081 ggctcgtcgc atcctggggc tgtagtcggt cccaagggtt gggctgttcg cccattaaag
     4141 cggcacgcga gctgggttca gaacgtcgtg agacagttcg gtccctatcc gtcgcgggcg
     4201 taggaaattt gagaggatct gctcctagta cgagaggacc agagtggact taccgctggt
     4261 gtaccagttg tcttgccaaa ggcatcgctg ggtagctatg tagggaaggg ataaacgctg
     4321 aaagcatcta agtgtgaaac ccacctcaag atgagatttc ccatgattat atatcagtaa
     4381 gagccctgag agatgatcag gtagataggt tagaagtgga agtgtggcga cacatgtagc
     4441 ggactaatac taatagctcg aggacttatc caaagtaact gagaatatga aagcgaacgg
     4501 ttttcttaag ttgaatagat attcaatttt gagtaggtat tactcagagt taagtgacga
     4561 tagcctagga gatacacctg tacccatgcc gaacacagaa gttaagccct agaacgccgg
     4621 aagtagttgg gggttgcccc ctgtg
//
LOCUS       DAVLXH010000091         4596 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00028199
            SAMN33607166-rid17955573.denovo.092, whole genome shotgun sequence.
ACCESSION   DAVLXH010000091 DAVLXH010000000
VERSION     DAVLXH010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607166
            Sequence Read Archive: SRR23725544
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4596)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4596)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721421.1
            Genome Coverage       :: 115x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:42:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,210
            CDSs (total)                      :: 2,161
            Genes (coding)                    :: 2,023
            CDSs (with protein)               :: 2,023
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 73 of 138
            Pseudo Genes (incomplete)         :: 60 of 138
            Pseudo Genes (internal stop)      :: 40 of 138
            Pseudo Genes (multiple problems)  :: 31 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4596
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607166-rid17955573.denovo.092"
                     /strain="AUSMDU00028199"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1349"
     gene            complement(1..170)
                     /locus_tag="VYO11_002076"
                     /pseudo
     CDS             complement(1..170)
                     /locus_tag="VYO11_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(216..449)
                     /locus_tag="VYO11_002077"
     CDS             complement(216..449)
                     /locus_tag="VYO11_002077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEV1596564.1"
                     /translation="MTEKEIFDRIVTIIQERQGEDFVVTESLSLKDDLDADSVDLMEF
                     ILTLEDEFSIEISDEEIDQLQNVGDVVKIIQGK"
     gene            complement(455..1447)
                     /gene="plsX"
                     /locus_tag="VYO11_002078"
     CDS             complement(455..1447)
                     /gene="plsX"
                     /locus_tag="VYO11_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000717456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HEV1596565.1"
                     /translation="MKKIAVDAMGGDYAPQAIVEGVNQALSDFSDIEVRLYGDEAKIK
                     QYLTATERVSIIHTDEKIDSDDEPTRAIRNKKNASMVLAAKAVKDGEADAVLSAGNTG
                     ALLAAGFFIVGRIKNIDRPGLMSTFPTVDGKGFDMLDLGANAENTAQHLHQYAVLGSF
                     YAKNVRGIAQPRVGLLNNGTESSKGDPLRKETYELLAADESLNFIGNVEARDLMNGVA
                     DVVVADGFTGNAVLKSIEGTAMGIMGLLKTAITGGGLRAKLGALLLKDSLSGLKKQLN
                     YSDVGGAVLFGVKAPVVKTHGSSDAKAVYSTIRQIRTMLETDVVAQTAREFSGE"
     gene            complement(1444..2214)
                     /gene="recO"
                     /locus_tag="VYO11_002079"
     CDS             complement(1444..2214)
                     /gene="recO"
                     /locus_tag="VYO11_002079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000616164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HEV1596566.1"
                     /translation="MIQSITSQGLVLYNRNFREDDKLVKIFTEQVGKRMFFVKHAGQS
                     KLAPVIQPLVLARFLLRINDDGLSYIEDYHEVMTFPKINSDLFVMAYATYVAALADAS
                     LQDNQQDAPLFAFLQKTLELMEAGLDYQVLTNIFEIQILTRFGISLNFNECVFCHRVG
                     QAFDFSFKYGACLCPEHYHEDKRRCHLNPNIPYLLNQFQAIDFETLETISLKPGIKQE
                     LRQFMDQLYEEYVGIHLKSKKFIDSLADWGQLLKEEKK"
     gene            complement(2211..3380)
                     /locus_tag="VYO11_002080"
     CDS             complement(2211..3380)
                     /locus_tag="VYO11_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEV1596567.1"
                     /translation="MDLTKRFNKQLDKIQVSLIRQFDQAISEIPGVLRLTLGEPDFTT
                     PDHVKEAAKRAIDQNQSYYTGMSGLLTLRQAASDFVKEKYQLDYAPENEILVTIGATE
                     ALSATLTAILEEGDKVLLPAPAYPGYEPIVNLVGAEIVEIDTTENGFVLTPEMLEKAI
                     LEQGDKLKAVILNYPANPTGITYSREQLEALAAVLRKYEIFVVCDEVYSELTYTGEAH
                     VSLGTMLRDQAIIINGLSKSHAMTGWRLGLIFAPAAFTAQLIKSHQYLVTAANTMAQH
                     AAVEALTAGKNDAEPMKKEYIQRRDYIIEKMTALGFEIIKPDGAFYIFAKIPAGYNQD
                     SFAFLKDFAQKKAVAFIPGAAFGRYGEGYVRLSYAASMETIKEAMKRLEEYMREA"
     gene            3529..4539
                     /locus_tag="VYO11_002081"
     CDS             3529..4539
                     /locus_tag="VYO11_002081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YeiH family putative sulfate export transporter"
                     /protein_id="HEV1596568.1"
                     /translation="MSFLSKNGAGILVCLLISILSWYLGGFFPVIGAPVFAIFMGMLL
                     HPFLSSYKQLDVGLTFSSKKLLQYAVILLGFGLNISQVFAVGQSSLPVILSTISIALI
                     VAYLFQRFFALDTKLATLIGVGSSICGGSAIAATAPVIHAKEKEVAQAISVIFFFNVL
                     AALIFPTLGTWLHLSNDGFALFAGTAVNDTSSVTATASAWDSLYQTNTLESATIVKLT
                     RTLAIIPITLFLSYWQSREQKNKQGLQLKKVFPLFILYFILASLLTTLLTSLGVSSSF
                     FTPLKQLSKFLIIMAMSAIGLKTNLVAMVKSSGKSIVLGAVCWIAIILTSLGMQTLIG
                     IF"
BASE COUNT         1199 a         1183 c          873 g         1341 t
ORIGIN      
        1 ttctcaacct tgcttctctc cttagatagc gcatgattac aggctttatc ttcaactgtt
       61 agcggcttga gtttgctgga tttacgtgga gtttgtgctt gaggatatat cttcatgagc
      121 ccttgataac cactgtcagc caagatttta ccagcttgtc cgatatttct catttctaaa
      181 aaccatctac ttccgttgac ttggaactcc gattgctatt ttccttgaat gattttaacc
      241 acatctccta cgttttggag ttggtcaatt tcttcatcgc tgatttcgat actaaattca
      301 tcttccagag tcaagataaa ctccatcaag tcaacagaat ccgcatccaa atcgtctttc
      361 agactcaagg attctgtcac gacaaagtcc tctccctgtc gctcttggat aatggtcaca
      421 atacggtcaa aaatttcttt ttctgtcatc tcttttattc tcctgaaaat tcacgcgcag
      481 tctgggcaac cacgtctgtt tctagcatgg tacggatctg acgaatcgta ctataaacag
      541 ccttggcatc gcttgagcca tgagtcttga caacaggtgc cttaacacca aacaagaccg
      601 ctccaccaac atctgaataa ttgagctgtt ttttcaaacc actgaggctg tccttgagaa
      661 ggagggcacc tagtttcgct cgaagaccac cacctgtaat agctgtcttg agcaagccca
      721 tgattcccat agctgtccct tcgatggatt tgagcacagc gtttcccgtg aaaccatctg
      781 ccacaacaac atctgcaacg ccattcatca aatcacgcgc ttccacgttt ccgataaagt
      841 tcaaactttc atcagccgcc agtaattcat aagtttcctt acgaagcggg tcgcccttgc
      901 tactctctgt tccgttgttg agcaaaccaa cgcgtggttg cgcaatgcca cggacatttt
      961 tagcatagaa ggaacctaga accgcatatt gatggaggtg ctgggctgta ttttctgcat
     1021 tggcaccaag gtctagcatg tcaaaacctt ttccatcaac ggtaggaaag gtagacatga
     1081 gtccaggacg gtcgatattc ttgatacgac ccacgatgaa gaatcctgct gccaacaagg
     1141 cacctgtatt cccagccgaa aggacagcgt ctgcttcacc atctttgaca gccttggctg
     1201 ccaataccat actggcattt ttcttattcc taatagctct cgtaggttca tcatccgaat
     1261 caatcttctc atccgtatgg ataatgctga cgcgctctgt cgctgtcaga tattgcttga
     1321 ttttagcttc atctccgtaa agtcgaacct cgatatctga aaagtcagat agggcttgat
     1381 tgacaccctc aacaatggcc tgaggtgcgt aatcgccccc catggcatct actgcgattt
     1441 ttttcatttc ttttcctctt ttagtaattg tccccagtct gctagggaat caataaattt
     1501 ctttgatttt aggtgaatcc caacgtactc ttcatataat tgatccataa attggcgtag
     1561 ctcttgcttg attccaggct tgagcgaaat ggtctccaaa gtctcaaaat caatagcttg
     1621 aaattgattg agcagatagg ggatattggg attgagatga caacgtctct tatcctcatg
     1681 ataatgctct ggacagaggc aggctccata tttgaaagaa aagtcaaaag cctgaccaac
     1741 ccgatggcag aagacacact cattaaaatt gaggctgatt ccaaatcgag tcaaaatttg
     1801 aatttcaaaa atattggtca aaacctgata atccaagcct gcttccatca actccaaagt
     1861 cttttgcaaa aaagcaaaca agggagcatc ctgctgattg tcctgcaaac tagcatctgc
     1921 aagagctgcc acataggtcg cataggccat gacaaagagg tcactattaa tcttgggaaa
     1981 agtcatgacc tcatgatagt cttcgatgta actgagtccg tcatcattga ttcgcaagag
     2041 aaatcgtgcc agcaccaagg gctgaataac aggcgccagc ttagactgac cagcgtgttt
     2101 gacaaaaaac atgcgtttgc caacctgctc tgtaaaaatt ttgacgagct tgtcatcctc
     2161 acgaaaattg cgattgtaaa gcaccaagcc ttgactcgtg atagactgaa tcatgcttct
     2221 ctcatgtact cctcaagtcg tttcatggct tctttgatag tctccatgct ggctgcataa
     2281 gataggcgga cgtagccttc cccgtaacgt ccaaaggctg caccagggat aaaggcaacg
     2341 gccttcttct gagcaaaatc cttcagaaaa gcaaaggagt cttgattgta gcccgctgga
     2401 attttagcaa aaatatagaa ggcaccgtct ggtttgataa tctcaaaacc aagagcagtc
     2461 attttttcga tgatatagtc ccgacgctgg atatattcct tcttcatggg ctccgcatca
     2521 tttttaccag ccgtcaaggc ttctaccgca gcatgttgcg ccatggtatt tgcggcagtg
     2581 accaagtatt ggtgactctt gattaactgg gctgtgaagg ccgcaggagc gaaaatcagc
     2641 cccaaacgcc aacctgtcat ggcatgcgat ttagacaaac cattgataat aatagcctgg
     2701 tctctcaaca tcgttcctag agacacatgg gcttcgcctg tgtaggtcaa ttctgagtaa
     2761 acctcatcac agacaacaaa aatttcgtac ttgcgtaaaa cagctgccaa ggcctctaac
     2821 tgctctcgac tgtaggtaat tcctgtcgga ttggctggat agttgagaat aaccgccttg
     2881 agcttatcac cctgctccaa aatggccttc tccaacatct caggagtcaa gacaaaacca
     2941 ttttcagtcg tatcaatctc aacaatttct gccccaacta agttaacaat cggttcatag
     3001 cctggataag caggagctgg caaaagtacc ttgtctccct cttccaaaat agccgtcaaa
     3061 gtcgcagata aagcctctgt cgccccaatt gtaaccaaga tttcattttc aggagcatag
     3121 tccagttggt acttttcctt aacaaagtca ctagctgcct gacgtagagt cagcagacca
     3181 ctcatccctg tatagtagga ttggttctga tcaatcgctc gcttggccgc ctccttgaca
     3241 tggtctggcg ttgtaaaatc aggttccccc aaggtcaaac gcaagacccc aggaatctcc
     3301 gaaatagcct ggtcaaactg acgaatcaac gaaacttgaa ttttatctaa ctgtttatta
     3361 aagcgcttag ttaagtccat agatacctcc tactttcaaa acgtatctct attatactac
     3421 aaaagccccc cgaccgcaaa aatacattag agaatagctt tccactttct attttacttt
     3481 tcctctttac aggtctataa tggtaacaga ttctatttgg aggtttttat gtcatttcta
     3541 tcaaaaaatg gagcaggcat cttggtctgc cttctcattt ccatcctatc ttggtactta
     3601 ggaggattct tccctgttat tggcgcaccc gtttttgcga tttttatggg aatgctccta
     3661 catccctttc tctcgtctta taaacaactg gatgttggat tgacctttag ttccaagaaa
     3721 ttgctccagt atgccgttat cttacttggt tttggtctca atatctctca agtcttcgca
     3781 gttgggcaat cttcactccc tgtcatcctt tccaccattt caatagcctt gattgttgcc
     3841 tacctcttcc agcgcttctt tgccctggat acaaaactgg ctaccttgat tggagtaggt
     3901 tcttctatct gtgggggttc tgccattgca gcgacagcgc ctgttatcca tgctaaggaa
     3961 aaggaagtag cccaagccat ctccgttatc tttttcttca atgtcttggc tgcgctcatc
     4021 tttccaaccc tcggcacctg gcttcatcta tccaatgacg gcttcgccct ctttgcagga
     4081 actgcggtca atgatacttc ctctgtaacc gccacagcta gcgcttggga cagtctctac
     4141 cagaccaata ccctcgaatc cgcaaccatt gtcaaactca cgcgcaccct agctatcatc
     4201 cccatcactc tctttctctc ctactggcaa agtcgcgagc aaaaaaataa gcaaggctta
     4261 caactgaaaa aagtcttccc actttttatc ctttacttca tccttgcatc gctcctaacc
     4321 acccttctga cctctctcgg tgtgtctagt agtttcttta cccctctcaa acaactctct
     4381 aaattcctca ttatcatggc catgagtgcc atcggtctca aaactaatct ggtcgctatg
     4441 gtcaaatcca gtggaaaatc cattgttctc ggagccgtct gctggattgc catcatcctc
     4501 accagccttg gtatgcagac ccttatcggc attttctaat actcttcgaa aatctcttca
     4561 aaccacgtca acgtcgcctt gccgtaggta tatgtt
//
LOCUS       DAVLXH010000092         4388 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00028199
            SAMN33607166-rid17955573.denovo.093, whole genome shotgun sequence.
ACCESSION   DAVLXH010000092 DAVLXH010000000
VERSION     DAVLXH010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607166
            Sequence Read Archive: SRR23725544
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4388)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4388)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721421.1
            Genome Coverage       :: 115x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:42:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,210
            CDSs (total)                      :: 2,161
            Genes (coding)                    :: 2,023
            CDSs (with protein)               :: 2,023
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 73 of 138
            Pseudo Genes (incomplete)         :: 60 of 138
            Pseudo Genes (internal stop)      :: 40 of 138
            Pseudo Genes (multiple problems)  :: 31 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4388
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607166-rid17955573.denovo.093"
                     /strain="AUSMDU00028199"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1349"
     gene            74..1063
                     /gene="manX"
                     /locus_tag="VYO11_002082"
     CDS             74..1063
                     /gene="manX"
                     /locus_tag="VYO11_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HEV1596569.1"
                     /translation="MSIGIIIASHGEFAAGIHQSGSMIFGEQEKVQVVTFMPNEGPDD
                     LYAKFNNAVAAFDAEDEVLVLADLWSGSPFNQASRVMGENPERKFAIITGLNLPMLIQ
                     AYTERLMDAAAGVEKVAANIIKEAKDGIKALPEELNPVEEVASAAAAPVAQTAIPEGT
                     VIGDGKLKINLARLDTRLLHGQVATAWTPDSKANRIIVASDNVAKDDLRKELIKQAAP
                     GNVKANVVPIQKLIEISKDPRFGETHALILFETPQDALRAIEGGVPIKTLNVGSMAHS
                     TGKTLVNTVLSMDKEDVATFEKMRDLGVEFDVRKVPNDSKKDLFDLINKANVK"
     gene            1091..1894
                     /locus_tag="VYO11_002083"
     CDS             1091..1894
                     /locus_tag="VYO11_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HEV1596570.1"
                     /translation="MSIISMVLVIVVAFFAGLEGILDQFQFHQPLVACTLIGLVTGHL
                     EAGIILGGSLQMIALGWSNIGAAIAPDAALASVAAAIIMVLGGDFTKTGIGVAQAVAI
                     PLAVAGLFLTMIVRTISVGLVHTADAAAKKGDFGAVERAHFIALLFQGLRIALPAALL
                     LMVPTETVQSILSAMPDWLKDGMAIGGGMVVAVGYAMVINMMATREVWPFFALGFVLA
                     AVSDITLIGFGAIGVAIALIYLHLSKTGGNGGGGAATSNDPIGDILEDY"
     gene            1918..2829
                     /locus_tag="VYO11_002084"
     CDS             1918..2829
                     /locus_tag="VYO11_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEV1596571.1"
                     /translation="MTEKLQLTKSDRKKVWWRSTFLQGSWNFERMQNLGWAYTLIPAI
                     KKLYTKKEDQIAALERHLEFFNTHPYVAAPVMGVTLALEEERANGVEIDDAAIQGVKI
                     GMMGPLAGIGDPVFWFTVRPILGSLGASLALTGNILGPLLFFVAWNLIRMSFLWYVQE
                     IGYKAGSEITKDMSGGILQDITKGASILGMFILAVLVQRWVNIKFAFDVSKVQLDEKA
                     YIHWDKLPEGSKGIQEAFAQVGQGLSQTPEKVTTFQQNLDMLIPGLSGLLLTLLCMYL
                     LKKKVSPITIILALFAVGIVAHVLHIM"
     gene            complement(2885..4219)
                     /gene="pepC"
                     /locus_tag="VYO11_002085"
     CDS             complement(2885..4219)
                     /gene="pepC"
                     /locus_tag="VYO11_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000991632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase C"
                     /protein_id="HEV1596572.1"
                     /translation="MNAIQESFTDKLFANYEANVKYQAIENAASHNGIFAALERRQSH
                     VDNTPVFSLDLTKDKVTNQKASGRCWMFAALNTFRHKLISQYKLENFELSQAHTFFWD
                     KYEKSNWFLEQVIATSDQELTSRKVSFLLQTPQQDGGQWDMVVSLFEKYGVVPKSVYP
                     ESVSSSSSRELNAILNKLLRQDAQILRDLLVSGADQVTVQAKKEDLLQEIFNFLAMSL
                     GLPPRKFDFAYRDKDNNYKSEKGITPQEFYKKYVNLPLEDYVSVINAPTADKPYGKSY
                     TVEMLGNVVGSRAVRYINVPMERLKELAIAQMQAGETVWFGSDVGQLSNRKAGILATD
                     VYDFESSMDIKLTQDKAGRLDYSESLMTHAMVLTGVDLDENGKSTKWKVENSWGDKVG
                     TDGYFVASDAWMDEYTYQIVVRKELLTAEEQAAYGAEPIVLAPWDPMGALAK"
BASE COUNT         1198 a          949 c          922 g         1319 t
ORIGIN      
        1 aaacggttta tacttaaaca gtcttaaagt tttcttaaat gaaaactaaa acaaaaaagg
       61 aggaatgaca ataatgagta tcggaatcat tattgcgagc cacggcgaat ttgctgctgg
      121 tattcatcag tcaggatcta tgatctttgg tgaacaagaa aaggttcaag ttgtgacctt
      181 tatgccaaat gaaggtcctg atgatctata cgctaagttt aataacgctg ttgctgcatt
      241 tgacgcagaa gatgaggttc tagttttggc tgacctttgg agtggttctc catttaacca
      301 agctagtcgc gtgatgggag aaaatcctga gcgtaagttt gccatcatca caggacttaa
      361 cttaccgatg ttgattcaag cctacacaga gcgcctcatg gacgctgctg caggtgtaga
      421 aaaagtcgct gctaatatca ttaaagaagc caaagatggc atcaaagctc ttccagaaga
      481 gctaaatcca gttgaagaag ttgcaagcgc tgcagctgct ccagttgccc aaactgctat
      541 cccagaagga actgttatcg gagacggtaa attgaaaatc aatcttgccc gtcttgacac
      601 acgtctactt cacggtcagg ttgcaactgc ttggactcca gattcaaaag caaatcgtat
      661 catcgttgct tcagataacg tggctaaaga cgaccttcgt aaagaattga ttaaacaagc
      721 agctccaggt aatgtcaagg ctaacgtggt tccaattcaa aaactgattg agatttcaaa
      781 agacccacgt tttggagaaa cacatgccct tatcttgttt gaaacacctc aagatgccct
      841 tcgtgccatc gaaggcggcg tgccaatcaa gactcttaac gttggttcta tggctcactc
      901 aacaggtaaa acattggtca ataccgtttt gtctatggac aaagaagatg ttgctacatt
      961 tgaaaaaatg cgtgacttgg gtgttgaatt tgatgtccgt aaagtaccaa atgattctaa
     1021 aaaagatttg tttgacttga ttaacaaagc caatgtcaaa taagccatta tttatgaaag
     1081 gattttaaac atgtctatta tttctatggt tttagtaatc gttgtagcct tctttgcagg
     1141 tcttgaaggc atcctcgacc agttccaatt tcaccaacca cttgtagcct gtacccttat
     1201 tgggcttgta acaggtcact tggaagcagg gattatcctc ggtggatcgc ttcaaatgat
     1261 tgcccttggt tggtcaaata tcggtgctgc tatcgctcct gatgctgcac ttgcttctgt
     1321 cgctgctgcc attatcatgg ttcttggtgg tgactttacc aagactggta tcggtgttgc
     1381 ccaagcggtt gctatccctc ttgccgtagc tggacttttc ttgacaatga ttgttcgtac
     1441 aatttcagtt ggtttggttc atactgcaga tgctgccgct aaaaaaggtg acttcggcgc
     1501 tgtggagcgt gcgcatttca ttgcgctact tttccaagga cttcgtatcg cgcttcctgc
     1561 agctcttctc cttatggtac caactgaaac tgtacaaagt atccttagtg ccatgccaga
     1621 ctggctcaaa gatggtatgg ctatcggtgg tggtatggtc gttgccgttg gttacgccat
     1681 ggttatcaac atgatggcaa ctcgtgaagt atggccattc ttcgctcttg gtttcgttct
     1741 cgctgctgtg tcagatatta ctctaatcgg attcggtgct atcggtgttg ctatcgctct
     1801 tatctacctt cacctttcta aaactggtgg aaatggtggc ggaggagccg caacttctaa
     1861 cgacccaatc ggcgatatcc tagaagacta ctaagataag aaaggactga aaacatcatg
     1921 actgaaaaac ttcaattaac taaatcagat cgtaaaaaag tttggtggcg ttcaaccttc
     1981 ttacaagggt cttggaactt tgaacggatg caaaacttgg gctgggctta tacactcatt
     2041 ccagctatca aaaaactcta tactaaaaaa gaagatcaaa tcgctgctct tgagcgtcac
     2101 cttgagttct tcaacactca tccatacgta gctgctccag tcatgggggt tactcttgcg
     2161 cttgaagaag aacgtgctaa cggtgtggaa atcgatgacg ctgctatcca aggggttaaa
     2221 atcggtatga tgggacctct tgctggtatc ggtgacccag tattctggtt tacagtacgc
     2281 ccaatccttg gatctctcgg tgcttcactt gcccttactg gcaatatctt ggggccactc
     2341 ctcttctttg ttgcatggaa cttgattcgt atgtcattct tgtggtatgt tcaagagatt
     2401 ggatacaagg ctggatcaga aatcactaaa gatatgtctg gtggtatcct tcaagatatc
     2461 actaaaggag cttctatcct tgggatgttc attcttgctg tccttgttca acgctgggta
     2521 aatattaaat ttgctttcga tgtttctaaa gttcaactag atgaaaaggc ttatatccat
     2581 tgggataaat tgccagaagg gtctaaaggt atccaagaag cattcgcaca agtaggacaa
     2641 ggattgtctc aaactcctga aaaagttact actttccaac aaaacttgga tatgttgatt
     2701 cctggattat caggactact ccttacttta ctttgcatgt acttacttaa gaaaaaagta
     2761 tctccaatca ctattatcct tgccctcttc gcagtgggta ttgtggcaca tgttcttcac
     2821 atcatgtaat caagcaacta aaaaggaacc aggttctaaa atctgattcc ttttttctat
     2881 gcttttattt agccaaggct cccattggat cccatggtgc aagtacaatt ggttctgctc
     2941 cataggcagc ttgttcttct gctgtcagca attccttacg aacaacgatt tggtatgtgt
     3001 attcgtccat ccaagcgtct gaggcaacaa agtaaccatc tgtaccgacc ttgtctcccc
     3061 atgagttttc aaccttccac ttggttgatt taccattttc gtccaagtca acacctgtca
     3121 agaccatggc gtgggtcatc aagctttcgc tatagtccaa acgtccagcc ttgtcttgag
     3181 taagtttaat gtccatgctt gattcaaagt cataaacatc tgtcgcaagg attccagcct
     3241 tacggttact gagctggccg acatcagaac caaaccaaac agtctcacct gcttgcattt
     3301 gggcaatcgc caattctttc aagcgctcca ttggaacgtt gatgtaacga actgcacggc
     3361 taccaaccac attccccaac atctcaactg tgtaagattt tccgtaaggt ttatcagcag
     3421 ttggagcatt gataacagaa acgtagtctt ctaaaggaag attgacatat ttcttgtaga
     3481 actcttgtgg tgtgattcct ttttcacttt tgtagttgtt atctttatcg cgataagcaa
     3541 agtcaaactt gcgtggtgga agtcctaatg acatagcaag aaagttaaag atttcttgca
     3601 agaggtcttc tttcttagct tgaacagtca cttgatctgc accagaaaca agcaaatcac
     3661 gcaagatttg agcatcttga cgaagcaatt tattaaggat cgcatttagc tcacgactgc
     3721 tgctagatga aacagactca ggataaactg acttaggcac gacaccgtat ttttcaaaga
     3781 gggaaacgac catatcccat tgaccaccat cttgttgagg tgtttggagt aagaagctaa
     3841 ccttgcggct agtcaattct tggtctgaag tcgcaatgac ttgctccaag aaccagtttg
     3901 atttctcata cttatcccag aagaaagtgt gggcttgtga caactcaaag ttctccaatt
     3961 tgtattgcga gatgagtttg tggcggaagg tgttgagagc cgcaaacatc cagcaacgac
     4021 cagacgcttt ctggttagtg accttgtcct tggttaaatc caatgagaaa acaggtgtgt
     4081 tgtctacatg gctttggcga cgttccagag ctgcaaaaat tccgttgtgg ctggcagcat
     4141 tttcaatcgc ttggtatttt acatttgctt catagttggc aaatagttta tcagtaaatg
     4201 attcttgaat cgcgttcata gattcctcct tttattctac agtctattat aactcttttc
     4261 acaaaggaag caactaaaaa acataaaagg taaggacatt ctccctcacc tttttcgaat
     4321 ttatactctt cgaaaatctc ttcaaaccac gtcaacgtcg ccttgccgta ctcaagtaca
     4381 gcctgcgg
//
LOCUS       DAVLXH010000093         4267 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00028199
            SAMN33607166-rid17955573.denovo.094, whole genome shotgun sequence.
ACCESSION   DAVLXH010000093 DAVLXH010000000
VERSION     DAVLXH010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607166
            Sequence Read Archive: SRR23725544
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4267)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4267)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721421.1
            Genome Coverage       :: 115x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:42:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,210
            CDSs (total)                      :: 2,161
            Genes (coding)                    :: 2,023
            CDSs (with protein)               :: 2,023
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 73 of 138
            Pseudo Genes (incomplete)         :: 60 of 138
            Pseudo Genes (internal stop)      :: 40 of 138
            Pseudo Genes (multiple problems)  :: 31 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4267
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607166-rid17955573.denovo.094"
                     /strain="AUSMDU00028199"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1349"
     gene            complement(300..833)
                     /locus_tag="VYO11_002086"
     CDS             complement(300..833)
                     /locus_tag="VYO11_002086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HEV1596573.1"
                     /translation="MKLPKEGDFITIQSYKHDGSLHRTWRDTMVLKTTENAIIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNIIAMIRDNGTSYYCNMASPYYLDEEALKYI
                     DYDLDVKIFTDGEKRLLDVEEYERHKRKMNYSDDLDYILKEHVKILVDWINNGRGPFS
                     EAYVNIWYKRYVELKNR"
     gene            complement(922..1698)
                     /gene="recX"
                     /locus_tag="VYO11_002087"
     CDS             complement(922..1698)
                     /gene="recX"
                     /locus_tag="VYO11_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000705102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HEV1596574.1"
                     /translation="MKITKLEKKKRLYLMELDNVDKCYITEDTIVRFMLSRDKVISKE
                     ELTEIQDFAQFSYGKNLALYHLSFKARTEKEVREYLKKYDIDENIVSQVIANLKEDKW
                     INDGQYAYTIINTNQLSGDKGPYVLTQKLAQKGISKSTIEENLKEFDFSEVAQRVANK
                     LLKKYEGKLPARALQDKIIQNLTNKGFSYSDAKIAFDDLDSQVDQETTQELIFKELDK
                     QYTKYARKYEGYELKQRLTQVLARKGYDFSDIASVLREYL"
     gene            complement(1708..2484)
                     /locus_tag="VYO11_002088"
     CDS             complement(1708..2484)
                     /locus_tag="VYO11_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001086342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside 3'-phosphotransferase"
                     /protein_id="HEV1596575.1"
                     /translation="MNSKTPRFSILDFPEQLRSYIKGANLSDSSSHSSATVLYIDSGY
                     YLKIDQKGRLAQEAKITSWFETEGLGTPVITYLSANKDFLLTKEAIGSNALAFLNQPE
                     KLCQTLAQALNKLHSLKPQSFPSENHLKRYKEKALKNYQKGTFYNKTLLPQFHIHSRE
                     EAYQLIQEKGYILKADAFIHGDACLPNFILKDASHFSCFIDLGLAGFSDRHIDLFWAI
                     WSLHYNLQDATYAELFLDYYGREYVNMDKLRLVAAFEAFR"
     gene            2541..3896
                     /gene="rlmD"
                     /locus_tag="VYO11_002089"
     CDS             2541..3896
                     /gene="rlmD"
                     /locus_tag="VYO11_002089"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HEV1596576.1"
                     /translation="MNLKVKQKIPLKIKRMGINGEGIGFYQKTLVFVPGALKGEDIYC
                     QITSIRRNFVEAKLLKVNKKSKFRIVPSCTIYNECGGCQIMHLHYDKQLEFKTDLLHQ
                     ALKKFAPAGYENYEIRPTIGMQEPKYYRAKLQFQTRKFKNQVKAGLYAQNSHYLVELK
                     DCLVQDKETQVIANRLAELLTYHQIPITDERKVLGVRTIMVRRARKTGQVQIIIVTNR
                     QLNLTQLVKELVKDFPEVVTVAVNTNTAKTSEIYGEKTEIIWGQESIQEGVLNYEFSL
                     SPRAFYQLNPEQTEVLYSEAVKALDVDKEDHLIDAYCGVGTIGFAFAKKVKTLRGMDI
                     IPEAIEDAKRNAKRMGFDNTHYEAGTAEEIIPRWYKEGYRADALIVDPPRTGLDDKLL
                     DTILTYVPEKMVYISCNVSTLARDLVRLVEVYDLHYIQSVDMFPHTARTEAVVKLIKK
                     V"
     gene            3958..4029
                     /locus_tag="VYO11_002090"
     tRNA            3958..4029
                     /locus_tag="VYO11_002090"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3991..3993,aa:Glu,seq:ttc)
BASE COUNT         1369 a          738 c          804 g         1356 t
ORIGIN      
        1 atgtggaaat acaaaaaaat gtttttgata cgaagttgac ctgtattttt tatactaatc
       61 attttcgtat tttttgtatt aaacgatata agtttgttgt aaacttacaa ggaataaaga
      121 cattaaaaaa taacagtata tctatttgtt ttatatattt tacgaattct gcataaattt
      181 ctttctagta atgtgttgta actctgctat aatggattta ttcctttttg tgtttacaca
      241 atttatttta tactaccaaa aaaacaaggt caggattttg ttcctgacct ttgacaactt
      301 taccgattct ttagttctac atagcgcttg taccaaatgt ttacataggc ttctgagaaa
      361 ggaccacgtc cattgttaat ccaatcaaca agaattttga catgttcttt taaaatatag
      421 tccaagtcat cagaataatt cattttgcgt ttgtgacgct cgtattcttc aacgtccaag
      481 agacgttttt ccccatctgt aaaaatttta acatccaaat cgtaatcaat atacttcagt
      541 gcttcttcat ccagatagta ggggctagcc atattgcaat agtaagaagt tccattatca
      601 cgaatcatgg caatgatatt aaaccaatat ttcttgtgaa agtaaacaat agccggttct
      661 cgagtgaccc aacgacgacc atcactttcg gtaacaagtg tatgatcgtt gacaccaata
      721 atggcgtttt ctgttgtttt tagtaccatg gtgtcccgcc aagttcggtg gagactccca
      781 tcatgcttat aactttgaat tgtaataaag tcgccttctt ttggaagctt cataactaac
      841 caactttcta caatttataa gtttatcatt tactattgta ccataaaatt acctaaaatc
      901 tgtgaatttc acttggaaat attaaagata ttctctaaga acgcttgcta tatccgaaaa
      961 atcgtagccc tttcgtgcta aaacttgagt taaacgctgc ttcagttcgt atccttcata
     1021 ctttcgggca tacttagtat attgcttatc aagttccttg aagatgagtt cctgagtcgt
     1081 ttcttggtca acttggctat ctaagtcgtc aaaggcaatt ttagcatcag aataagagaa
     1141 gcccttgtta gtcaagttct ggataatctt atcttgcagg gcacgagctg gaagttttcc
     1201 ctcatatttt ttcaatagtt tattagctac acgttgagca acttcagaaa aatcaaattc
     1261 tttcaagttc tcttctatag tagattttga aatccctttt tgagctagtt tctgagtcag
     1321 cacataagga cccttgtctc ctgaaagttg attggtattg atgatagtat aagcgtactg
     1381 accatcatta atccacttat cttctttaag attagcaata acttgagaaa cgatgttttc
     1441 atcaatatcg tattttttca gatattctct gacttctttt tcagtgcgtg ctttaaagga
     1501 taagtggtag agggccagat tcttaccata agaaaactgg gcaaaatcct gaatctcggt
     1561 cagttcctct ttactaatga ccttatctct cgataacata aaacgaacaa ttgtgtcttc
     1621 ggtgatatag catttgtcga cattatcaag ctccatcaga tagagtcttt ttttcttttc
     1681 aagttttgtg attttcataa tttcctttca tctaaatgct tcgaaagctg caacaagtcg
     1741 gagtttatcc atatttacat attctctacc gtaatagtcg agaaataatt cagcatacgt
     1801 agcatcttgt aggttgtaat gaagggacca aattgcccaa aagaggtcga tatgtcggtc
     1861 actaaaacca gccaatccca agtcaataaa gcaagaaaaa tgagaggcat ccttcaagat
     1921 gaaatttggc aggcaggcat ctccatgaat aaaagcatca gctttgagaa tgtaaccttt
     1981 ctcttgtatc agttggtaag cttcttcacg actgtgaatg tgaaattgag gcagaagagt
     2041 cttgttataa aaagtcccct tctgatagtt ttttaaggct ttttctttat aacgcttcag
     2101 atgattttcc gacggaaaag attgtggttt aagactgtga agtttgttta atgcttgagc
     2161 cagggtttga cagagttttt cgggttgatt taaaaaagcg agagcgttgc tgccaatggc
     2221 ttctttagtc agaaggaagt ccttatttgc tgataaatag gtaatcactg gagttcccaa
     2281 tccttcagtt tcgaaccaac ttgtaatctt agcttcttga gctaatctgc ctttttgatc
     2341 tatttttaaa tagtaacctg aatctatata taggacagtt gcacttgaat gagaagaact
     2401 atcagagaga ttagctccct tgatatagct tcgtaattgt tcagggaaat ctagtatact
     2461 aaagcgaggt gtttttgaat tcatgctttt attgtaacat attcttaaat atcttagaaa
     2521 ctccatggta taatagacat atgaatctga aagtgaaaca aaaaatacca ttaaaaatca
     2581 agcgcatggg aattaacggt gagggaatcg gcttttacca aaaaacatta gtctttgtac
     2641 caggagctct caaaggcgaa gatatctatt gtcagattac ttctattaga cgcaactttg
     2701 ttgaagcaaa attactgaag gtcaacaaga agtctaaatt tcgaattgtg ccatcttgta
     2761 ctatttataa tgaatgcgga ggctgccaaa tcatgcacct gcattatgat aagcagctgg
     2821 agttcaagac ggacttactt catcaagcgc tgaaaaaatt tgctcctgca ggatatgaaa
     2881 attatgaaat tcgtccaact attggaatgc aggaaccaaa atattacaga gctaagttac
     2941 aatttcagac tcgaaaattt aaaaatcagg tcaaggcggg cttatatgca caaaactctc
     3001 actatttagt agagttgaaa gactgcctgg tacaagataa ggaaacccaa gtgattgcta
     3061 atcgcttagc agaattactt acttatcacc agattccaat cacggatgag agaaaagttc
     3121 taggtgtccg tactattatg gtccgacgcg cgagaaagac cggacaggtt cagattatta
     3181 ttgttacaaa ccgccagctt aatttaactc aattggtaaa agagttggtt aaagatttcc
     3241 cagaagttgt gacagtagct gttaatacaa atacagctaa aaccagtgag atatatggtg
     3301 aaaagacaga gattatctgg gggcaagaga gtattcaaga aggtgtactc aattatgaat
     3361 tttcactatc ccctcgagct ttttatcaac taaatcctga gcaaacagaa gtcctctata
     3421 gcgaagcagt aaaagcgctg gatgttgata aagaagacca tttgattgac gcttattgtg
     3481 gagttggaac gattggattt gcctttgcaa agaaagtaaa aacactcaga ggtatggata
     3541 ttattccaga agctattgaa gatgccaagc gaaatgctaa aagaatggga tttgacaata
     3601 ctcattatga agctggaacg gcagaagaga ttattcctcg ttggtacaag gaaggctacc
     3661 gagcagatgc tttgattgtt gacccaccac gtacaggtct ggatgataag ttattagata
     3721 ctattcttac ttatgtacca gaaaaaatgg tttatatttc ttgtaatgtt tcgaccttgg
     3781 ctcgtgattt ggtacgctta gtagaagtct atgatcttca ttatatccag tcggtcgata
     3841 tgttcccaca tacagctcga actgaagctg ttgtaaaatt aataaaaaaa gtttaaaaaa
     3901 ggtgttgaca aagtttgaaa agactgtata atagtaagag ttgaaaataa caactcaggt
     3961 ccgttggtca aggggttaag acaccgcctt ttcacggcgg taacacgggt tcgaatcccg
     4021 tacggactat ggtatgttgc ggttggaaca cttgatgaaa aaaagtttaa aaaagcttaa
     4081 aaatcttcaa aaaagtgttg acaagtgaaa gtggctgtga tatactaata tagttgtcgc
     4141 ttgagagaag caagtgacaa agacctttga aaactgaaca agacgaacca atgtgcaggg
     4201 cgctacaaca taagttgtag tactgaacaa tgaaaaaaca ataaatctgt cagtgacaga
     4261 aatgagt
//
LOCUS       DAVLXH010000094         3920 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00028199
            SAMN33607166-rid17955573.denovo.095, whole genome shotgun sequence.
ACCESSION   DAVLXH010000094 DAVLXH010000000
VERSION     DAVLXH010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607166
            Sequence Read Archive: SRR23725544
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3920)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3920)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721421.1
            Genome Coverage       :: 115x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:42:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,210
            CDSs (total)                      :: 2,161
            Genes (coding)                    :: 2,023
            CDSs (with protein)               :: 2,023
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 73 of 138
            Pseudo Genes (incomplete)         :: 60 of 138
            Pseudo Genes (internal stop)      :: 40 of 138
            Pseudo Genes (multiple problems)  :: 31 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3920
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607166-rid17955573.denovo.095"
                     /strain="AUSMDU00028199"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1349"
     gene            266..1669
                     /locus_tag="VYO11_002091"
     CDS             266..1669
                     /locus_tag="VYO11_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase"
                     /protein_id="HEV1596577.1"
                     /translation="MNNDEWVYQYPIGKFVERQGWKIHISSEYNSSHELLQDVAKICH
                     EMRIPFKHLSTEDKFIMRNGKLVSRGFSGKFITCYPNQNELESVLQRLESALKQYNGP
                     YILSDKRWDEAPIYLRYGVFRPSRDDEKKVVIDELIVGDEVVKDERLPVFKIPKGIVP
                     PDFLNKWLDKKDKKQGDFPFIIDNAIRFSNSGGIYNARLKEDGKKIILKEARPYTGLG
                     FDGTYSSERLASECKALKILNEWSEMPKIYWYGKIWEHTFLGIEHMKGVPLNRWVTNN
                     FPLYEVVDKTKDYLLRVSKIVEKLIDLTNKFHSENVYHQDLHLGNILVKDEDEISIID
                     WEQAVFSNDEKVVHKVAAPGFRAWRETLPSEIDWYGIRQIAHYLYMPLVTTSDLTYNY
                     VSQTRIEGKKLFESLGYTREHIDYVESLLSYLDSKCPQIENISRKKVLKPMHEIRTIE
                     SEQDIQDFIIKAFLLVN"
     gene            1858..2478
                     /locus_tag="VYO11_002092"
     CDS             1858..2478
                     /locus_tag="VYO11_002092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000656069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV1596578.1"
                     /translation="MKDVVYSITPENKLSIDFSFKSPFRVLLTGTSGSGKTTILNLIN
                     GSLKPQKGYVNLLSHGKKSSDSIPTVDQTPYIFDTTIRENVTLFQNEYFSDDQIIEVL
                     KKVNLYEELEKIDILNYKCGENGSNLSGGQKQKIALARALIRNNKVYLFDEISANLDN
                     DNSNSIHDILFNLGISFIEVSHHYDLNDKRYTDIYKLENGTLFKIK"
     gene            2493..3233
                     /locus_tag="VYO11_002093"
     CDS             2493..3233
                     /locus_tag="VYO11_002093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000356590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1596579.1"
                     /translation="MDKDYILKVKGLYHQFLLGNNKTLQVLKNVSLSASRGEFISILG
                     ISGSGKSTLLKCISSLLEPTSGEVILNGINPYKIRNAKLSSIRRNEVSFIFQAYNLIP
                     SLPVIENIALPLRLSQKKLTIKNVENLLKRMKFNAGLNDFVGTLSGGEQQKVAIARAV
                     IADSDIIFADEPTGALDSVSREVIFELLRELVGAGKCVIMVTHDIELASKTDRALILK
                     DGKIFKELHRPSGEELYKILEVQSTTEE"
     gene            3236..>3920
                     /locus_tag="VYO11_002094"
     CDS             3236..>3920
                     /locus_tag="VYO11_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000945307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HEV1596580.1"
                     /translation="MLRLVYYQFLHNKKQWLGVSPVIFVSSLVMGLAVNGVINVENNS
                     QVFVGLPDPKPIFMFPIVFGGVTLFFVLSNIINMLVEIFRDDYELLEVLGASRLQLSF
                     LVGGQIFIISSIISFIAYLCSIFVTSNYYYFLQYFFGENILPDIQFQTSAVGCIITVV
                     LISFLAFLSGCFYTFKKIRNRKSSKIRHVLSIVKRILLLAGFSVIWLLSLQQIFQDST
                     ILAKAQIIFN"
BASE COUNT         1379 a          496 c          760 g         1285 t
ORIGIN      
        1 gattctctgg agttatggat ctcgttccaa tatgtgcacg ttggaatgtc agtgcttata
       61 tggggggaat ccaaaggatt ctcccttttt attttaataa gtctgtctag ctatagatat
      121 attaagtttg atagaatttc ttggagattt tgttatggat tataatttca atttggagca
      181 tcctttcttt ttcactaata atgattatag tacagatact agcataaagt actaagtaag
      241 tctgcctttt aattggcacg aagtaatgaa taatgatgag tgggtttatc aataccctat
      301 tggaaaattt gttgaaagac aagggtggaa aatacacatt agttcagagt ataatagttc
      361 acacgaattg ttacaagatg tagcaaaaat ttgccatgaa atgcgaattc catttaaaca
      421 tcttagtaca gaagacaaat ttatcatgcg aaacgggaaa ttggttagtc gaggattttc
      481 tggtaaattt attacatgtt atccaaatca aaatgaatta gagtcggttt tgcaaaggtt
      541 agaaagtgcc ttaaagcaat ataatgggcc atatatttta agcgataaac gttgggatga
      601 agcaccaata tatctgaggt atggtgtgtt taggccgtca agggatgatg aaaagaaggt
      661 tgttattgat gaattaattg ttggcgatga agttgttaaa gatgaacgtt taccagtatt
      721 taaaattcca aaaggtatag tgccccctga ctttttgaat aaatggcttg acaagaaaga
      781 taaaaaacag ggagactttc cctttattat agataatgca attagatttt caaacagtgg
      841 tgggatatat aatgctagac taaaagaaga tgggaaaaaa ataattttaa aagaggctag
      901 accgtataca ggtctaggat ttgatggtac ttattcttca gagagattag cttcggagtg
      961 caaagcacta aaaattctaa atgaatggag tgagatgcct aaaatatact ggtacggtaa
     1021 gatctgggag cacaccttct taggaattga acatatgaag ggcgttccac taaatagatg
     1081 ggttaccaat aattttcctt tatatgaagt tgttgataag accaaagatt atctattgag
     1141 agtttcaaag atagtagaaa aactcatcga tttaacgaat aagtttcatt ctgaaaatgt
     1201 atatcatcaa gatttacatt taggaaatat cttggttaag gatgaagatg agattagtat
     1261 aatagactgg gaacaggctg tcttttcgaa tgatgaaaaa gttgtacata aagttgcagc
     1321 ccctggtttt agagcatggc gagaaacact tcccagtgag atagattggt atggtattag
     1381 acaaatagct cattatttat acatgccact agtaactaca tcggatttga catacaacta
     1441 tgtaagtcaa accaggatag aaggaaaaaa actatttgag tctttgggtt atacaagaga
     1501 acatatagat tatgtagaaa gtttattgtc atatctagat tctaaatgtc cacagattga
     1561 gaatatttcc aggaaaaaag ttttaaaacc catgcatgag attagaacta tcgagagtga
     1621 gcaagatata caagatttta ttataaaagc ttttctttta gtgaactgat aggtattttc
     1681 ttagcaaacg ataaagtttt agggccgata caatcaattg cctattcatt aaataagata
     1741 aatacaacca aagatttaag gaaaccgttt ttaaaatact taagtggaga gaagaatttt
     1801 gtagacgctg aacatgataa taacggactg tatacttcat caatagatga gatacacatg
     1861 aaagatgttg tatattctat tacaccagaa aataaattaa gtattgactt ctcatttaag
     1921 tcaccattta gggtattatt aacaggaact tctggcagtg ggaaaacaac gattttaaat
     1981 ttaattaatg gttctttaaa gccacaaaaa ggttatgtaa atttgttatc acatgggaaa
     2041 aagagttcag attcaatacc aacagttgat cagacaccat atatttttga cactactatt
     2101 cgtgagaacg taactttatt tcaaaatgaa tatttttcag atgatcagat aattgaggtg
     2161 ttaaaaaagg taaatctata tgaagaatta gaaaagatag atatactaaa ttataaatgt
     2221 ggtgaaaatg gtagtaattt gtctggaggt caaaaacaaa aaatagcttt agctagagct
     2281 ctgattagaa ataataaagt gtacttattt gacgaaatat cagctaattt agataatgat
     2341 aattcaaatt ccatacatga tattctgttc aatttaggta tttcatttat tgaagtttca
     2401 catcattatg acttaaatga caagagatac actgatatat ataaattgga aaatggaaca
     2461 cttttcaaaa ttaagtgatt ggaggcaaga atatggataa agattatata ttaaaagtga
     2521 aagggctgta tcatcaattt ttactaggaa ataataaaac gttgcaagtg ctgaaaaatg
     2581 tttctctttc tgcttcgaga ggagaattta taagtattct aggaattagt ggttctggaa
     2641 agtcaacttt attaaaatgt atttctagtt tgcttgaacc aacaagtggg gaagtaattt
     2701 taaatggaat caacccctat aaaatcagaa atgcaaaatt gtcaagtata agacgtaacg
     2761 aagtatcttt tatatttcaa gcatacaatt taataccttc cctgccggta atagaaaata
     2821 tagcacttcc tttgcgatta tcacaaaaaa aattaactat taaaaatgta gaaaacttac
     2881 tcaaaagaat gaagtttaat gctggcttaa acgattttgt tggaactctg tctggtggag
     2941 aacaacagaa ggttgctata gctagagcgg ttattgctga tagtgatata atatttgctg
     3001 atgagccaac tggggcttta gacagcgttt ctcgtgaagt aatttttgaa ttattgagag
     3061 agttagtagg ggcgggtaag tgtgtaatta tggtaacgca cgatatagaa ttggcctcga
     3121 aaactgatcg tgcattaata ttgaaagatg gaaaaatttt caaagaactt catagaccta
     3181 gcggggaaga gttgtataaa atcttagagg tacaatcaac tacggaggaa tagagatgct
     3241 cagattagtt tactatcaat ttttacataa taagaaacaa tggttaggcg tttcaccagt
     3301 aatttttgtt tcgagtttag ttatgggatt ggctgttaat ggggtaatta atgttgagaa
     3361 taattcgcaa gtatttgtcg gacttccaga tcctaaacca atttttatgt ttccgatagt
     3421 attcggagga gtaacattat tctttgtgct ctctaacata ataaatatgt tggttgaaat
     3481 ttttagagat gattacgaac ttctggaggt gttgggagca agtcgccttc aactatcatt
     3541 tcttgtgggg ggacagattt ttatcatttc ctcgattatt agttttattg catatctatg
     3601 ctctatattt gttacgtcaa attattatta ttttttacaa tactttttcg gggaaaatat
     3661 attacctgat atccaatttc aaacgagtgc tgttggatgt atcattacag tagtgttgat
     3721 ttcattttta gcctttctaa gtggttgctt ttatacgttc aagaagatta gaaataggaa
     3781 gagttctaaa ataaggcatg ttctttcaat agtaaaaaga atactgctat tggctggttt
     3841 tagtgttatc tggttgcttt ctttgcaaca aattttccaa gatagcacaa ttttagcgaa
     3901 ggcccagata atattcaata
//
LOCUS       DAVLXH010000095         3553 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00028199
            SAMN33607166-rid17955573.denovo.096, whole genome shotgun sequence.
ACCESSION   DAVLXH010000095 DAVLXH010000000
VERSION     DAVLXH010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607166
            Sequence Read Archive: SRR23725544
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3553)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3553)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721421.1
            Genome Coverage       :: 115x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:42:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,210
            CDSs (total)                      :: 2,161
            Genes (coding)                    :: 2,023
            CDSs (with protein)               :: 2,023
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 73 of 138
            Pseudo Genes (incomplete)         :: 60 of 138
            Pseudo Genes (internal stop)      :: 40 of 138
            Pseudo Genes (multiple problems)  :: 31 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3553
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607166-rid17955573.denovo.096"
                     /strain="AUSMDU00028199"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1349"
     gene            complement(<1..463)
                     /locus_tag="VYO11_002095"
     CDS             complement(<1..463)
                     /locus_tag="VYO11_002095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001111259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1596581.1"
                     /translation="MPANTKVIFQEMFADFQNYYVLIGGTATSIVLDSQGFKSRTTKD
                     YDMVIIDEVKNKEFYTTLNHFLELGEYQGSQKDEKAQLFRFTTTNSEFPSMIELFSIL
                     PEYPLKKDGREIPLYFDQDASLSALLLDEDYYNILVHVKETIQGYSVLSNCG"
     gene            complement(453..650)
                     /locus_tag="VYO11_002096"
     CDS             complement(453..650)
                     /locus_tag="VYO11_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000890145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1596582.1"
                     /translation="MLEIWKYRPFVSEFWNDFKNNHDKQFVDPISLYLTLKDDDDPRI
                     EEESEALENMILQYLGEDDAS"
     gene            complement(654..1448)
                     /locus_tag="VYO11_002097"
     CDS             complement(654..1448)
                     /locus_tag="VYO11_002097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001101205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1596583.1"
                     /translation="MNVKKIMSIFQSFYVDVSIEELTLTLPISFVKRFEYTQMTFHKE
                     SFLLIKEKRRGSLSSFVTQARTMGEKANMDVVLVFSKLSDSEKKQLLQARVPFVDFKG
                     NLFFPPLGLVLNANDTEIPKELTPSEQLTWIAFLLTKGQKVVNVDLLSQVTGLPNSTI
                     YRCLRTFKALYWLNKQNKLYTYTVSKKELFLKSVSCLFNPIKKRILLPDGDIKQIKSV
                     SNLLYGGAYALSHSTFLVETDENTSYVIWQRKFNQLSLPLSQHVLK"
     gene            complement(1856..2281)
                     /locus_tag="VYO11_002098"
     CDS             complement(1856..2281)
                     /locus_tag="VYO11_002098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000204068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1596584.1"
                     /translation="MTSRVFIDADCISVFLWVGTEHLLEKLYSGKIVIPQEVYDEINI
                     PTIPHLKSRIDQLVAKGSAEIVSIDIGTEEYALYRDLTRNHDSNKIIGKGEAASISLA
                     KKHNGILGSNNLRDVKSYVEEFSLEHMTTGDILIEAFKV"
     gene            complement(2410..2769)
                     /locus_tag="VYO11_002099"
     CDS             complement(2410..2769)
                     /locus_tag="VYO11_002099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1596585.1"
                     /translation="MKKSSVSLILIGEGDETERKADQFASYFLIFPSSLYRMVEEIRE
                     NANRTHLEVEDIIKLGQFYGISHKVMLYRLRNDGYLDAEEIKNMDISVIETASRLGYD
                     TSLYRPLSESKKEMSLG"
     gene            complement(2815..3021)
                     /locus_tag="VYO11_002100"
     CDS             complement(2815..3021)
                     /locus_tag="VYO11_002100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1596586.1"
                     /translation="MDLSNKAPNLRKKLGADGESPIDIFKLVQKIENLTLVFYGLGKN
                     ISGVCYKGTQFSLIAVNSDMPLGR"
     gene            complement(3008..3169)
                     /locus_tag="VYO11_002101"
     CDS             complement(3008..3169)
                     /locus_tag="VYO11_002101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1596587.1"
                     /translation="MNMINVCDVGKRIKELRISSNLTQDKIAEYLSLNQSMIAKMEKG
                     ERNITNGFK"
BASE COUNT         1147 a          706 c          446 g         1254 t
ORIGIN      
        1 gaccacaatt actcaatacc gaatacccct gaatggtttc ttttacatgc accaatatat
       61 tataataatc ttcatccaat aataaggctg ataaactagc atcttggtca aaatataagg
      121 gaatttctcg accgtccttc tttaatggat attctggtaa gatactaaat agttcaatca
      181 tagaaggaaa ctcagaatta gttgttgtaa atcgaaaaag ctgcgctttc tcatctttct
      241 gacttccttg atactctccc aattctaaaa aatgattcaa ggtagtataa aattccttat
      301 tttttacttc atcaatgatg accatatcat aatcttttgt tgtgcgactt ttaaatcctt
      361 gcgaatccaa tacgatagag gtagcagttc ccccaatcag aacataatag ttctgaaaat
      421 ccgcaaacat ttcttgaaaa ataactttcg tattagctgg catcatcttc tcccagatac
      481 tgtaatatca tattttctag tgcttcactc tcttcctcta tacgtgggtc atcatcatct
      541 tttaaggtca aataaagaga aatcggatct acaaattgtt tatcatgatt atttttaaaa
      601 tcattccaaa actcagatac aaaaggacga tatttccata tctctagcat ctttcatttt
      661 aaaacatgct gagaaagtgg caaggataac tgattgaatt ttctctgcca tatgacatag
      721 ctagtatttt catccgtttc aactaaaaaa gttgaatgcg acaaagcata agcaccacca
      781 tatagaaggt tagaaacaga ttttatctgc tttatatcgc catctggcaa taaaatccgt
      841 tttttgatgg gattaaataa acatgacacg gattttaaga ataattcttt ctttgacacc
      901 gtatatgtgt aaagcttatt ttgcttgttt aaccaatata aagctttaaa agtcctcaaa
      961 cacctataaa ttgttgagtt tggaagtcca gtgacttgtg aaagcaaatc aacatttact
     1021 actttttgac cttttgtcaa taaaaaggca atccacgtta attgttcgct aggtgttaat
     1081 tccttaggga tttcagtatc attcgcattg agtactagtc ccaatggagg gaagaaaagg
     1141 tttcccttaa agtctacaaa cggaactcta gcttgaagta attgcttttt ttcactgtct
     1201 gataacttcg aaaacaccaa aacaacatcc atattggctt tttcacccat agtgcgagcc
     1261 tgagtaacaa atgaactcaa actccccctt ctcttttctt taatcaataa aaatgattcc
     1321 ttatgaaaag tcatttgagt atactcaaac ctttttacaa aactgattgg taaagtcaaa
     1381 gtcagttcct caatactgac atcaacataa aaggattgaa aaattgacat tatctttttg
     1441 acattcatgt tttttcctta ttctatcatt tttattatat tttatcattc ggtataataa
     1501 aatataagtt ttttgataaa ataaccaaaa actactcgct atcccctctc acattaccct
     1561 acatatcgtt tgacatgcga ctgatagttc aggaaaactt caaggagaac ttttctctca
     1621 tccactatgc aggacttact atttcacttc tactcctata ggctcaattt gacacttttc
     1681 tttttcgaat tgctcatatg cctcctgaat agtgagttcg atttatccaa atttattttt
     1741 gtctattttg atgaatactt ccacgaagat agtctgaaaa tgaatttgca ccaattttcc
     1801 ttctcttttt aagcatatta ttccagatat gattgccctc ttgttcagta ataaattaca
     1861 ctttaaacgc ttcaatcagt atatctcctg ttgtcatatg ttctaaagaa aattcttcta
     1921 catatgattt aacatctctt aggttattac ttcctaatat cccattatgc tttttcgcta
     1981 aggaaataga agccgcttct cccttaccaa taatcttgtt actatcatga tttcttgtta
     2041 aatctctata taatgcgtat tcttcagttc caatgtctat gctcacaatc tcagctgaac
     2101 ccttagctac caactggtct atcctagatt ttaaatgggg aattgtaggt atattgattt
     2161 catcatacac ctcttgtgga ataacaattt tacccgaata gagcttttct aaaagatgtt
     2221 cagtgccaac ccataaaaat actgaaatac aatctgcatc aataaataca cgactagtca
     2281 aacgacaact cccccctctt catctagccc atatacaata tcatatctga aagcatctag
     2341 taacagttcc tcatacttcc cttgcgaaat tctgttattt tctaaaagtt gttcagttga
     2401 attaatatat tatcctaatg acatttcctt tttactttct gacaaaggac gatataaact
     2461 tgtatcatag cctaatcttg aagctgtctc tataacacta atatccatat ttttaatttc
     2521 ttctgcatca aggtatccat cattcctcaa tctatataac ataactttat gactgatacc
     2581 ataaaactga cccaatttta taatatcttc tacttcaaga tgagttctat tggcattttc
     2641 tctgatttcc tcaaccatcc tatacagtga agatgggaaa attaaaaaat aagaagcaaa
     2701 ctgatccgct tttctttcag tttcatctcc ttcaccaatc aagataagac tgactgaact
     2761 cttcttcacc tcatcataat aaagatgata cagtccatgt gctaaagaaa atctttacct
     2821 tcctaatggc atatctgaat tgactgcaat gagactgaac tgagttcctt tataacagac
     2881 tccgctaata ttctttccga gtccataaaa taccagcgtc aaattttcta tcttttgtac
     2941 caatttaaaa atatctatcg gcgattcacc atcagctccc aacttttttc taagatttgg
     3001 agctttatta cttaaatcca ttcgtgatat tcctttcacc tttttccatt ttggcaatca
     3061 tgctttgatt caaagacaaa tactcagcaa tcttatcttg agtaagattt gaagatattc
     3121 taagttcttt tattcttttt ccaacatcac atacatttat catattcata cacctctcat
     3181 aaaaagaata gcacactctt gtcataattt tttaaataaa aaaattatga caaaacaagg
     3241 aagcaattta ttgatgctgc ttaaaaatct aaaattgatg agttcctatc aaaaatcgta
     3301 tcttcaacct caaaacagta cttaaagcta tccgactcgg tttacattgt caaatttaga
     3361 ttttatttga gcataacttt ctagtttgct ttttgatttt tgtttaatat agtagcaaaa
     3421 attgaaggaa atatctccac aagaaaacgc atactattaa gctttttcaa gacctaataa
     3481 tatgcgctgt tctgatttga aagatattcc attattattt tactgtaatc aagccatctg
     3541 gctctactgt gaa
//
LOCUS       DAVLXH010000096         3426 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00028199
            SAMN33607166-rid17955573.denovo.097, whole genome shotgun sequence.
ACCESSION   DAVLXH010000096 DAVLXH010000000
VERSION     DAVLXH010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607166
            Sequence Read Archive: SRR23725544
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3426)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3426)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721421.1
            Genome Coverage       :: 115x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:42:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,210
            CDSs (total)                      :: 2,161
            Genes (coding)                    :: 2,023
            CDSs (with protein)               :: 2,023
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 73 of 138
            Pseudo Genes (incomplete)         :: 60 of 138
            Pseudo Genes (internal stop)      :: 40 of 138
            Pseudo Genes (multiple problems)  :: 31 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3426
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607166-rid17955573.denovo.097"
                     /strain="AUSMDU00028199"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1349"
     gene            160..2793
                     /gene="polA"
                     /locus_tag="VYO11_002102"
     CDS             160..2793
                     /gene="polA"
                     /locus_tag="VYO11_002102"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014932012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HEV1596588.1"
                     /translation="MDKKKLLLIDGSSVAFRAFFALYQQLDRFKNAAGLHTNAIYGFQ
                     LMLSHLLERVEPSHILVAFDAGKTTFRTEMYADYKGGRAKTPDEFREQFPFIRELLDH
                     MGIRHYELAQYEADDIIGTLDKLAEQDGFDITIVSGDKDLIQLTDEHTVVEISKKGVA
                     EFEAFTPDYLMEEMGLTPAQFIDLKALMGDKSDNIPGVTKVGEKTGIKLLLEHGSLEG
                     IYENIDGMKTSKMKENLINDKEQAFLSKTLATIDTKAPIAIGLEDLVYSGPDVENLGK
                     FYDEMGFKQLKQALNVSSADVAKGLDFTIVDQISQDMLSEESIFHFELFGENYHTDNL
                     VGFAWSCEDKLYATDKLELLQDPIFKDFLEKTSLRVYDFKKVKVLLQRFGVDLQAPAF
                     DIRLAKYLLSTVEDNEIATIASLYGQTYLVDDETFYGKGVKKAIPEREKFLEHLACKL
                     AVLVETEPILLEKLSENGQLELLYDMEQPLAFVLAKMEIAGIMVKKETLLEMQAENEL
                     VIEKLTQEIYELAGEEFNVNSPKQLGVLLFEKLGLPLEYTKKTKTGYSTAVDVLERLA
                     PIAPIVKKILDYRQIAKIQSTYVIGLQDWILADGKIHTRYVQDLTQTGRLSSVDPNLQ
                     NIPARLEQGRLIRKAFVPEWEDSVLLSSDYSQIELRVLAHISKDEHLIKAFQEGADIH
                     TSTAMRVFGIERPDDVTANDRRNAKAVNFGVVYGISDFGLSNNLGISRKEAKAYIDTY
                     FERFPGIKNYMDEVVREARDKSYVETLFKRRRELPDINSRNFNIRGFAERTAINSPIQ
                     GSAADILKIAMIQLDKALVAGGYQTKMLLQVHDEIVLEVPKSELVEMKKLVKQTMEEA
                     IQLSVPLIADENEGATWYEAK"
     gene            2878..3315
                     /locus_tag="VYO11_002103"
     CDS             2878..3315
                     /locus_tag="VYO11_002103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HEV1596589.1"
                     /translation="MSQEFINPSDGVIRRYLATSKTLAVVGLSDREETTSNRVTKEMQ
                     ARGYKIIPVNPKAAGGEILGEKAYASLAEIPFPVDIVNVYRRSEFLLDVARDFLKADA
                     KIFWAQLGLESLEAEEILRAGGCDDIVMNRCIKREHTRLIGEA"
BASE COUNT          924 a          606 c          879 g         1017 t
ORIGIN      
        1 tgtactatta tagattcaat atgctatatt atagcacatt tttaaatcta ggtttactag
       61 attctctggc tctatctatt tattcggaaa aagtttgaaa aatacttgct ctagctcttc
      121 ccaatggtat tttttgattc tttcctttat aatgggtgta tggataagaa aaaattatta
      181 ttgattgatg ggtcttctgt agcttttcgg gcgttttttg cgctgtatca gcagttggac
      241 cgttttaaga atgcggctgg tttgcatacc aatgcgattt atggtttcca gttgatgttg
      301 agtcatttgt tggagcgggt tgagccgagt catattttgg tggcttttga tgcgggaaag
      361 acgaccttcc ggacagagat gtatgcggac tataagggtg gtcgggccaa gactcctgat
      421 gagtttcgtg agcaatttcc tttcattcgt gagttgctgg atcatatggg gattcgtcac
      481 tatgagctgg ctcagtatga ggcggatgac atcattggga cgctggataa gctagcagag
      541 caggatggtt ttgatattac cattgtcagt ggggacaagg atttgattca gctgacggat
      601 gagcatacgg tggttgaaat ttccaagaaa ggtgtggctg agtttgaggc ctttacgcca
      661 gattacctca tggaagaaat gggcctcaca ccagctcagt ttatcgatct caaggcgctc
      721 atgggtgata agtcggataa tatccctggg gtgaccaaag tcggtgaaaa gacgggtatt
      781 aagctcttgc tggagcatgg ttcgcttgag gggatttatg aaaatattga tggaatgaag
      841 acttctaaga tgaaggaaaa tctcatcaat gacaaggaac aggccttttt gtctaaaaca
      901 ctagcgacca ttgataccaa ggcaccgatt gcgattggtt tagaggactt ggtctatagt
      961 ggtccagatg ttgaaaatct tgggaaattt tacgatgaga tgggcttcaa acagctcaag
     1021 caggctttaa atgtgtcgtc agctgatgtg gctaagggtt tagattttac tattgttgac
     1081 caaatcagtc aagatatgct gagtgaagag tctatcttcc actttgagct ttttggtgag
     1141 aattaccata cggataattt ggttggattt gcctggtctt gtgaggataa gctctatgcc
     1201 acagacaagc ttgagctgtt gcaagacccg attttcaagg atttcttaga aaaaacatct
     1261 ctgagagttt atgactttaa gaaggttaaa gttcttttgc aacgttttgg tgtggatttg
     1321 caggcgcctg cttttgacat ccgtttggct aaatacctcc tttcgactgt ggaggacaat
     1381 gaaattgcga ccatcgctag tctttatggt cagacttact tggttgatga tgaaactttc
     1441 tacggtaagg gtgttaaaaa ggccattcct gaacgtgaga aattcttgga acacttagct
     1501 tgtaaacttg ctgttttggt agaaacagag cctattttac ttgaaaaact cagcgaaaat
     1561 gggcaattag agcttcttta tgatatggag caacctctgg cttttgtcct tgccaagatg
     1621 gaaattgctg ggattatggt caagaaagag accttgcttg agatgcaggc tgaaaatgag
     1681 cttgtcattg aaaaactgac tcaagagatt tacgagctgg ctggtgagga gtttaatgtc
     1741 aactcgccta agcagttggg cgtgcttctc tttgagaaat tgggacttcc tctagaatac
     1801 actaagaaaa ccaagacagg ttattcgaca gcagtggatg tgttggagcg tctcgctcct
     1861 attgctccga ttgttaagaa aatcctggat taccgtcaaa ttgctaagat tcaatctact
     1921 tatgtaattg gcttgcagga ctggattttg gctgatggaa agattcatac tcgctatgtg
     1981 caggatttga cccagaccgg gcgtttgtct agtgtggatc caaacttgca aaatattcct
     2041 gcccgattgg aacaggggcg cttgattcgg aaggcttttg tgccagagtg ggaggatagt
     2101 gtgctactca gctctgacta ttcacagatt gaattgcgcg ttttggcgca tatttctaag
     2161 gatgagcact tgattaaggc cttccaagag ggggcagata tccatacttc gacagccatg
     2221 cgggtctttg gcattgagcg tcctgatgat gtgactgcaa acgaccgtcg caatgccaag
     2281 gcagttaact ttggagtggt ttatgggatt tcagactttg gcttgtctaa taatttggga
     2341 attagtcgta aggaagccaa agcctacatt gatacctact ttgaacgttt tccaggtatt
     2401 aaaaactaca tggatgaagt ggtgcgggag gcgcgtgata agagctatgt agagaccctc
     2461 tttaagcgtc gccgtgagtt gccagatatc aattcgcgca acttcaatat tcgtggtttt
     2521 gcggagcgaa ctgctatcaa ctcacctatc cagggttcgg cagcagatat tctcaagatt
     2581 gccatgattc agctggataa agccttggtt gcaggtggtt atcagactaa gatgctgtta
     2641 caagtgcacg atgaaatcgt ccttgaagtg cctaaatctg aattggtaga gatgaaaaaa
     2701 ttggtgaaac aaaccatgga agaagccatt caactcagtg ttcctcttat cgcagatgag
     2761 aatgaagggg caacctggta cgaggctaaa taaaaagggg gctagtcctc cttttttgta
     2821 gtagaattct gcaaaccttt tcaaaatatg ctatactgat gaaaaaggag gatttctatg
     2881 agtcaagaat ttatcaatcc aagtgatggc gtgattcgtc ggtatctcgc aacgagtaaa
     2941 acccttgctg tggtgggttt gtctgaccgt gaagaaacaa ccagcaatcg agtgacaaag
     3001 gaaatgcagg ctcggggcta taaaatcatc ccagtcaatc ccaaggcggc aggtggcgaa
     3061 atcttgggtg aaaaggctta tgctagcctc gctgaaattc cttttcctgt agatattgtc
     3121 aatgtttatc gtcgcagtga atttctgctc gatgtggcgc gtgattttct caaggctgat
     3181 gccaagattt tttgggcgca gctgggactt gaaagtctag aggcggaaga aatcttgcgt
     3241 gctggtggat gcgatgacat cgtgatgaat cgttgcatca agagagaaca tacacgcttg
     3301 attggggaag cataagaaaa aggtagctga tgggctacct tttgtgttat actcaatgaa
     3361 aatcaaagag caaactagga aactagctgc gggttgctca aaacactgtt ttgaggttgt
     3421 agatac
//
LOCUS       DAVLXH010000097         3191 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00028199
            SAMN33607166-rid17955573.denovo.098, whole genome shotgun sequence.
ACCESSION   DAVLXH010000097 DAVLXH010000000
VERSION     DAVLXH010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607166
            Sequence Read Archive: SRR23725544
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3191)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3191)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721421.1
            Genome Coverage       :: 115x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:42:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,210
            CDSs (total)                      :: 2,161
            Genes (coding)                    :: 2,023
            CDSs (with protein)               :: 2,023
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 73 of 138
            Pseudo Genes (incomplete)         :: 60 of 138
            Pseudo Genes (internal stop)      :: 40 of 138
            Pseudo Genes (multiple problems)  :: 31 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3191
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607166-rid17955573.denovo.098"
                     /strain="AUSMDU00028199"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1349"
     gene            <1..170
                     /locus_tag="VYO11_002104"
     CDS             <1..170
                     /locus_tag="VYO11_002104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEV1596590.1"
                     /translation="TVSFAISSKGEKMKVENISYRVDHRILFDNISFDTSSSGVTLIT
                     GKNGTGKSTLL"
     gene            complement(536..1846)
                     /locus_tag="VYO11_002105"
     CDS             complement(536..1846)
                     /locus_tag="VYO11_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HEV1596591.1"
                     /translation="MIHLIMISAIALAIGIGYRTKINIGLLAIAFSYLIATTLMGLSP
                     KELLHFWPTSLFFTIFSVSLFYNVATTNGTLDVLAQHILYRTRTHPNALYMILYLMAT
                     LLSALGAGFFTTMAVCCPLAITLCQKADKHPLIGAQAVNWGASGGANLITSSSGIVFQ
                     GLFKQMGWEEQAFSLGNHIFIVSIIYPLIVLLLLSCYSHYSKGRTNSSLTIDQPPLLS
                     KVQRQTTLLMISSMVLVWLFPLLHLIFPNIAWIATYQKTFDIGFVSILMVCLALRLKL
                     GKQEAILAKVPWATIIMLCGMSLLMSLAVKSGLVTLIGHLMTTTIPHFWLPLFFCVIA
                     GVMSLFSSTLSVVAPALFPIIAIISAQNPQIDIHLLTTATVIGALSTNISPFSSAGSL
                     IQLSLPNIEERGLAFKKQIILGVPISLSLGLLTTWILILLASLS"
     gene            2083..2955
                     /locus_tag="VYO11_002106"
     CDS             2083..2955
                     /locus_tag="VYO11_002106"
                     /EC_number="2.4.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylating nicotinate-nucleotide
                     diphosphorylase"
                     /protein_id="HEV1596592.1"
                     /translation="MSIISTDLTPFQIDDTLKAALREDVHSEDYSTNAIFDHHGQAKV
                     SLFAKEAGVLAGLTVFQRVFTLFDAEVTFQNPHQFKDGDRLTSGDLVLEIIGSVRSLL
                     TCERVALNFLQHLSGIASMTAAYVEALGDDCIKVFDTRKTTPNLRLFEKYAVRVGGGY
                     NHRFNLSDAIMLKDNHIAAVGSVQKAIAQARAYAPFVKMVEVEVESLAAAEEAAAAGA
                     DIIMLDNMSLEQIEQAITLIAGRSRIECSGNIDMTTISRFRGLAIDYVSSGSLTHSAK
                     SLDFSMKGLTYLDV"
     gene            3086..>3191
                     /locus_tag="VYO11_002107"
     CDS             3086..>3191
                     /locus_tag="VYO11_002107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
                     /protein_id="HEV1596593.1"
                     /translation="MAYSIDFRKKVLSYCERTGSITEASHVFQISRNTI"
BASE COUNT          982 a          538 c          717 g          954 t
ORIGIN      
        1 gaactgtttc ttttgctatt agttcaaaag gagaaaaaat gaaagtagaa aatatttcgt
       61 atagggtgga tcatcgtata ttgtttgata atatttcttt tgatacttcg agttcaggcg
      121 tgacattaat tactggtaaa aatggtacag gaaagtcaac tttactatag tagattgaaa
      181 ctagaatagt acacatctac ttctaaaata ttgttagaaa ttgatttgac tatcccgatc
      241 tatttgtcct gttcttattt catttcacta tatctcaaat tgagtatgac gaagtgcgct
      301 cccatgtcct gggaacgcac tttcttcata tttttcatat tcttgaatcc atcgataaag
      361 actattggga tgaattttta aagttgaact aatcattttt acaggatgag atttacagca
      421 gagagtttga aggctttatc aaaggttttt cttggcataa tgacttttcc tcgtttccac
      481 ttaattttgt gtctacttta ttataccaag tccaccctta agttagataa taaatctaac
      541 ttaaggaagc tagaaggatg agaatccagg tggtcaagag tcccaaactt aagctgatgg
      601 ggacacccag aataatttgc tttttgaagg caaggccacg ttcctctata ttgggaagtg
      661 agagttgaat gagagaacca gctgatgaaa agggtgagat attagtagat agagcgccaa
      721 taacggtggc tgttgtgagt aagtgaatat caatctgagg attttgagca ctgatgatag
      781 caatgatggg aaagagggct ggagctacaa cggatagggt ggaactaaag agtgacatca
      841 ctccggctat cacacaaaag aacagaggta accagaaatg aggaatggtt gttgtcatga
      901 ggtgccctat cagtgtgact aaacctgact tgaccgctag agacattagt aagctcatgc
      961 cgcagagcat gataattgta gcccagggaa ccttagctaa aatggcttct tgcttcccta
     1021 atttgagcct taaggcgagg cagaccatga gtattgagac aaagccaata tcaaatgttt
     1081 tttgataagt agctatccag gcgatgtttg ggaaaatgag atgcaacaag ggaaaaagcc
     1141 aaaccaaaac catgctgctg atcatgagca aggtggtttg tctttgaacc ttgctgagga
     1201 gtggtggttg gtcaatagtc aaggatgagt ttgttcttcc cttactatag tgactgtaac
     1261 aggataataa aagcaagacg atgagtgggt agataatgct gacgataaag atatgattgc
     1321 caagtgaaaa agcttgctcc tcccatccca tttgcttaaa caggccttga aagacaatgc
     1381 ctgagctact ggttatcaaa ttagcccctc ctgaagctcc ccaattgacg gcttgagctc
     1441 caatcaaagg gtgtttgtcc gctttttgac agagggtaat cgctagagga cagcaaacgg
     1501 ccatagtagt gaaaaatcca gcacctaaag cagacaaaag ggttgccatc aggtataaaa
     1561 tcatgtagag ggcgttaggg tgggtgcgtg tgcggtagag aatgtgttga gccaaaacat
     1621 caagagtacc gttagttgtt gcaacgttat aaaagagaga gacgctaaaa atggtaaaaa
     1681 agagtgaggt tggccaaaaa tgaagaagtt ctttggggct taatcccatg agagtggttg
     1741 cgatgaggta agaaaaagca atagccagca ggccaatatt gattttggtg cggtaaccaa
     1801 ttccaatggc tagagcaatg gcgctaatca ttattaaatg aatcattgaa ttgtcctttc
     1861 agttagaata tggaaatagg ttggcaattt tggcgctcaa aagaccacct gtttcctatt
     1921 ggtacttgac tattatacac aaaaaaaata caattgtctt gacaattgta ttgacacttg
     1981 ttagaattaa aaatgaggta ttcaggcttg tgatttccta tggaagttaa tagtaattgc
     2041 ctctagtgct tacaagtgat attaaaaata gaggacttag tgatgtcaat catttcaact
     2101 gatttaaccc cttttcaaat agatgataca ttgaaagcag ccttgcgaga agatgttcat
     2161 tccgaagatt acagtaccaa tgccattttt gatcatcatg gccaagccaa ggtgtcgctt
     2221 tttgccaagg aagctggtgt tttagcggga ctaaccgttt ttcaaagggt ttttacccta
     2281 tttgatgccg aggtgacctt ccagaatcct catcaattta aggatgggga tcgtttgact
     2341 agtggcgatt tggttttaga aatcataggc tcggtgagaa gtctcttaac atgtgaacgc
     2401 gttgccttga attttttaca acatttatca gggattgctt cgatgacagc tgcttatgta
     2461 gaagccttag gcgatgattg cattaaggta tttgatactc gaaaaactac tcctaattta
     2521 cgtctttttg agaaatatgc cgtgagagtt ggcggtggct ataatcatcg ctttaattta
     2581 tcagatgcta tcatgctaaa agacaatcac attgcggcag taggtagtgt tcaaaaggca
     2641 attgctcaag cgcgtgccta tgcccctttt gtgaaaatgg tcgaggtgga agtggaaagc
     2701 cttgctgctg ccgaagaagc tgcggcggcg ggtgctgata ttatcatgtt ggataatatg
     2761 tcattggaac agattgaaca ggccattacc ctaattgcag gacgttctcg gattgaatgt
     2821 tctggaaata ttgatatgac cactattagc cgttttcgtg gtttagcgat tgattacgtc
     2881 tccagtggta gtttaaccca tagtgctaag agtcttgatt tttccatgaa gggtttaacc
     2941 taccttgatg tctaagttgt aaaataaact aactttttaa aggatgtctt tcctctagaa
     3001 cgagttttat gtcagatagt ttaaacgcct cttcaaatat agtaaaatga accaaaaata
     3061 gtacaaaatg tggtataatc ttcttatggc atattcaata gattttcgta aaaaagttct
     3121 ctcttattgt gagcgaacag gtagtataac agaagcatca cacgttttcc aaatctcacg
     3181 taataccatt t
//
LOCUS       DAVLXH010000098         3001 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00028199
            SAMN33607166-rid17955573.denovo.099, whole genome shotgun sequence.
ACCESSION   DAVLXH010000098 DAVLXH010000000
VERSION     DAVLXH010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607166
            Sequence Read Archive: SRR23725544
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3001)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3001)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721421.1
            Genome Coverage       :: 115x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:42:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,210
            CDSs (total)                      :: 2,161
            Genes (coding)                    :: 2,023
            CDSs (with protein)               :: 2,023
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 73 of 138
            Pseudo Genes (incomplete)         :: 60 of 138
            Pseudo Genes (internal stop)      :: 40 of 138
            Pseudo Genes (multiple problems)  :: 31 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3001
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607166-rid17955573.denovo.099"
                     /strain="AUSMDU00028199"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1349"
     gene            28..1053
                     /locus_tag="VYO11_002108"
     CDS             28..1053
                     /locus_tag="VYO11_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000790748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-siderophore ABC transporter
                     substrate-binding protein"
                     /protein_id="HEV1596594.1"
                     /translation="MKNKFFLIAILAMCIVFSACSSNSVKNEENTSKEHAPDKIVLDH
                     AFGQTILDKKPERVATIAWGNHDVALALGIVPVGLSKANYGVSADKGVLPWTEEKIKE
                     LNGKANLFDDLDGLNFEAISNSKPDVILAGYSGITKEDYDTLSKIAPVAAYKSKPWQT
                     LWRDMIRIDSKALGMEKEGDELIKNTEARISKELEKHPEIKGKIKGKKVLFTMINAAD
                     TSKFWIYTSKDPRANYLTDLGLVFPESLKEFESEDSFAKEISAEEANKINDADVIITY
                     GDDKTLEALQKDPLLGKINAIKNGAVAVIPDNTPLAASCTPTPLSINYTIEEYLNLLG
                     NACKNAK"
     gene            1043..2050
                     /locus_tag="VYO11_002109"
     CDS             1043..2050
                     /locus_tag="VYO11_002109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001244688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEV1596595.1"
                     /translation="MRNKKQINLGIIFVICLGLLITIFLSLKLGTKEINIRDFLAAFG
                     MGNTNDDFIKSIIYKRIPRTIFAILAGSSLAISGVLMQSVTRNPIADPGILGINTGAS
                     LSVVIGLSFLGISSSISHISFAIIGGLVSAIFVYAIAVSGKAGLTPIKLALSGTCVSM
                     ALSSFVSFLILPNNNVLDKFRFWQIGSLGAATLSSISTLLPFIILGHLIAIFISSDLN
                     ALAMGDEMAVGLGVNVNRIRSLAIIASVLLCSSITAIGGPIGFVGLIVPHFCGLFISK
                     DIRTMTISSSFIGAELLLICDIIGRMLGKPGEIEVGIITAIIGGPVLIYVTMKNRGVN
                     N"
     gene            2050..>3001
                     /locus_tag="VYO11_002110"
     CDS             2050..>3001
                     /locus_tag="VYO11_002110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEV1596596.1"
                     /translation="MQNLIIGIQKRKNRITLFSSLFLLIIISLSFFILLIGDESYSFS
                     TLIKVLNSETVPGASFSIMEIRLPKLLAGIIAGWSFGLAGFIFQTMLRNPLASPDIIG
                     VTSSSSIAAVFCILVLKTNSLTTGIISITCGLTSSLILFLLAKKDGFSAARLIILGIG
                     FQAVTRAGTSFLLLKVARYELQEVMRWLSGSLSFTKLDDIPLVLIVSIIATILVLFFN
                     KRLEIIELGEEIAIGLGANPELSRLVLIFCAVSLTAFSTSITGPIACISFLAGPIALN
                     IGKKRSPILAGLVGVLLVLLSDIFSQNILPARYPVGVVTGL"
BASE COUNT         1015 a          429 c          526 g         1031 t
ORIGIN      
        1 gacttgaaat atgttcaagg agtttttatg aaaaacaaat tttttctaat agctatttta
       61 gctatgtgta tagtttttag cgcttgttct tctaattctg ttaaaaatga agaaaatact
      121 tctaaagagc atgcgcctga taaaatagtt ttagatcatg ctttcggtca aactatatta
      181 gataaaaaac ctgaaagagt tgcaactatt gcttggggaa atcatgatgt agcattagct
      241 ttaggaatag ttcctgttgg actttcaaaa gcaaattacg gtgtaagtgc tgataaagga
      301 gttttaccat ggacagaaga aaaaatcaaa gaactaaatg gtaaagctaa cctatttgac
      361 gatttggatg gacttaactt tgaagcaata tcaaattcta aaccagatgt tatcttagca
      421 ggttattctg gtataactaa agaagattat gacactctat caaaaattgc tcctgtagca
      481 gcatacaaat ctaaaccttg gcaaacttta tggagagata tgattagaat tgattcaaaa
      541 gccttaggta tggaaaaaga aggtgatgag ttaatcaaaa atactgaagc tcgtatatcc
      601 aaagaattag aaaaacatcc agaaatcaaa ggaaaaatca aaggaaaaaa agtattattt
      661 actatgatta atgctgcaga tacatcaaaa ttctggattt atactagcaa agatccaaga
      721 gcaaattatt taacagattt aggtctagtt ttccctgaat cattaaaaga atttgagagt
      781 gaagatagtt ttgcaaagga aatttctgca gaagaagcaa ataagataaa tgatgctgat
      841 gtaatcataa cttatggtga tgataaaact cttgaagctt tacaaaaaga tcctctttta
      901 ggtaaaataa atgcaattaa aaatggtgcc gttgctgtaa ttccagataa tacaccgtta
      961 gcagcctcat gcactccaac accactttca ataaactata ctattgaaga atatctaaat
     1021 cttttaggaa atgcatgcaa aaatgcgaaa taaaaaacaa ataaacctag gcataatttt
     1081 tgtaatctgc ctaggtcttc ttattacaat atttttgtca ttaaagcttg gaacaaaaga
     1141 aattaatatc agagattttt tagcagcttt tggaatgggt aatacaaatg atgattttat
     1201 taaatcaatt atatataaaa gaatacctag aactattttt gcaattttag caggttctag
     1261 tcttgccata agcggtgtat tgatgcaatc agttactaga aacccaatag ctgatccagg
     1321 tatactcggt ataaacacag gagcaagtct tagtgtagta attggtcttt cttttttagg
     1381 aatttcatca agcataagcc atataagttt tgcaatcatt ggtggcttag taagtgcaat
     1441 ttttgtatac gcgattgctg taagcggaaa agcaggcctt acccctataa aacttgcctt
     1501 atcaggaact tgtgttagta tggctttaag cagttttgta agttttttaa ttttaccgaa
     1561 taataacgtc ttagacaaat ttagattttg gcaaataggt agccttggag cagctacatt
     1621 atcttctata tctacactac taccttttat aattttaggt cacttgatag ctatatttat
     1681 ttcatcagat ttaaacgctt tagctatggg tgatgaaatg gctgttggtc ttggagttaa
     1741 tgttaatagg ataagatcac ttgcaataat tgcaagtgtg cttttatgtt caagtattac
     1801 tgcaattggt ggacctattg gcttcgtagg tcttatagtt cctcactttt gtggcttatt
     1861 tataagcaaa gatatacgca caatgaccat ttcttcatct tttataggtg cagagctctt
     1921 gcttatatgt gatataatcg gccgtatgtt aggtaaacca ggtgaaattg aagtagggat
     1981 aattactgca ataatcgggg gtccagtact tatttatgta actatgaaaa atagaggggt
     2041 taataactaa tgcaaaattt aattataggt attcaaaaaa gaaaaaatag aataacacta
     2101 ttctcctcac tatttttatt aataataatc agtctatcat ttttcatttt acttatcgga
     2161 gatgaaagtt attctttttc aactttgatt aaagtcttaa atagtgaaac tgttcctgga
     2221 gctagttttt cgattatgga aattagatta ccaaaattat tagcaggaat tatagctggc
     2281 tggtcttttg gattggcagg atttatcttt caaactatgt taagaaatcc tcttgcaagt
     2341 cctgatataa tcggtgtcac aagttcttca tctattgcag cggtcttttg catattggta
     2401 ttaaaaacaa atagtttaac tactggaatt atttcaataa cttgtggact aacatcatct
     2461 ttaatattat ttttactagc taaaaaagat ggtttttcag cagcaagact gataatatta
     2521 ggtattggtt ttcaagctgt cacaagagca ggcacctcat ttttattgtt gaaagtagca
     2581 agatatgaat tacaagaagt tatgagatgg ctcagtggct ctttatcttt tacaaagtta
     2641 gatgacatac ctcttgttct aatagtaagt attattgcta ctatattagt tttatttttt
     2701 aataaaagac tagaaattat tgaacttggt gaagaaatag caatcggact tggtgcaaat
     2761 cccgagcttt caaggcttgt tttaattttt tgcgctgtat ctttaactgc tttttctact
     2821 tcaattacag gaccaatagc ttgtatatct tttttagctg gtcccatagc cttaaatatt
     2881 ggcaagaaaa gaagcccaat attagctgga ttggttggag ttttactagt tttgttatca
     2941 gacatattct ctcaaaatat tttaccagct agatatccag taggtgttgt aactggcttg
     3001 t
//
LOCUS       DAVLXH010000099         2842 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00028199
            SAMN33607166-rid17955573.denovo.100, whole genome shotgun sequence.
ACCESSION   DAVLXH010000099 DAVLXH010000000
VERSION     DAVLXH010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607166
            Sequence Read Archive: SRR23725544
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2842)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2842)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721421.1
            Genome Coverage       :: 115x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:42:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,210
            CDSs (total)                      :: 2,161
            Genes (coding)                    :: 2,023
            CDSs (with protein)               :: 2,023
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 73 of 138
            Pseudo Genes (incomplete)         :: 60 of 138
            Pseudo Genes (internal stop)      :: 40 of 138
            Pseudo Genes (multiple problems)  :: 31 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2842
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607166-rid17955573.denovo.100"
                     /strain="AUSMDU00028199"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1349"
     gene            <1..793
                     /locus_tag="VYO11_002111"
     CDS             <1..793
                     /locus_tag="VYO11_002111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1596597.1"
                     /translation="WLFNISLVTVAVEGIGFAYGFNGGLTHKNFYAITILVSYILLFI
                     SRKHGTKYQVDSLVLWFDLFLLLVSNTRTIYIILVVFWIVVHSGFIKYIKKNHRPVII
                     TTWLVISLLSIIFFFKHIINNSESYTHRVLGIVNFFKYYESSKFHLFFGDAELAFGDM
                     TKGYTHNIRSVLGWDGTVEMPLLSVMIKNGYVGLIGYGVVLFKFISSVLSMEDRRVKN
                     IGLSILIPLLLSAMVENYIVNISFVFMPVCFCILCSIKNIEFKNN"
     gene            803..1771
                     /locus_tag="VYO11_002112"
     CDS             803..1771
                     /locus_tag="VYO11_002112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV1596598.1"
                     /translation="MKKVSIILPVYNVEQYIKKCLESIQQQTYPNLEVIIVNDGATDK
                     SVEYCEQICKIDSRFSVTHKENGGLSDARNVGIDKAKGDYLIFVDSDDFVSQDMVSYL
                     VSSMENNEADIAICDPAHYYSDRQNNDLNIFYPASSVKVYEKTEALCEMFYQKSFLVS
                     AWAKIYKKELFDDIRFPVGKLFEDSAVMYLLFEKCEKIVYSNAKLYAYVHRDNSITTK
                     KFSDKDLDILDISNTILDHYSGNFRVYKAAVSYKVSACFRILLNSSSEKKYNQIQKDC
                     MTYILRNWRNVLFDKNVRLKNKLALISITLFNPFVKFIYSKVNRWE"
     gene            1778..>2842
                     /locus_tag="VYO11_002113"
     CDS             1778..>2842
                     /locus_tag="VYO11_002113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001045980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 61 protein"
                     /protein_id="HEV1596599.1"
                     /translation="MNKYEERYQEDLSKNDFEKLINRRYLSDKELQVEYVKKGTVLPP
                     KVFEMKLSNKLGLQKALHGKGGVVDSKGNYVELSEQKAVGMRNRVYGSYKFNHKNLAI
                     RNEKVIYLNYFINQWGHFLLDVVGRLWYPLLKDTDTKLDYTCYAGTETKLEGNYLEFL
                     ELLGIDKSRLILINRPTQFSEIIIPESSILPGEYYTKEYKMLFNSLVANVKLDNNLES
                     KKIYCSRARLDLAKGKEFGENGIEKVFLKNGYTPVYMETMSLKEQIRTLLSATTIVLT
                     SGSLAHNLLFINNKINVFILNKTYRVNLHQFLINKISEASVSFVDIYRSPLPILYGYG
                     PFLMDITKPLVNFFEDSGFTY"
BASE COUNT         1000 a          349 c          496 g          997 t
ORIGIN      
        1 ttggctattt aatatttcat tagtaactgt tgctgttgag gggattggtt ttgcatatgg
       61 atttaatggt gggttgacgc ataagaattt ttatgcaatt acaattttag tttcctatat
      121 cctattgttt attagtagaa aacatggtac gaagtaccaa gttgatagct tagtattatg
      181 gtttgatctt tttttacttt tagtatctaa cacacggaca atatatataa tattagttgt
      241 tttttggatc gttgttcata gcggatttat taaatatata aagaaaaatc acagaccagt
      301 aattataacg acatggttag taatttcttt attatctata atattttttt tcaaacacat
      361 tataaataat agtgaatcct atactcatcg tgttttgggt attgttaatt tttttaaata
      421 ctacgaatct agcaaatttc atttattttt tggtgatgct gagttagcct ttggtgatat
      481 gacgaaaggt tatactcaca atataagaag tgttttaggt tgggatggaa ctgtggaaat
      541 gccgttgcta agtgttatga taaaaaatgg ttatgtcggc ttaatagggt atggagtagt
      601 cttatttaaa tttatatcct ctgtattatc tatggaagat agaagagtaa aaaatattgg
      661 cttatccatt ctaatacctc tacttctatc agcaatggtt gaaaattata tcgttaatat
      721 tagctttgta ttcatgccgg tctgtttttg tattttatgc tcaataaaaa atatagaatt
      781 taaaaataat tgaaagtgat ttatgaaaaa agtaagtatt attctacctg tctacaatgt
      841 tgaacagtat ataaaaaaat gcttagaatc aattcaacaa caaacttatc caaatttgga
      901 agtaatcatt gttaatgacg gagcaaccga taaaagcgtt gaatactgtg agcaaatttg
      961 taagatagat tctaggtttt ctgtcactca caaagaaaat ggtggacttt ccgatgcaag
     1021 aaatgtcggt atagataaag ccaagggaga ttacctcatt tttgttgaca gtgatgattt
     1081 tgtctctcaa gatatggtat cttatttagt atctagtatg gagaacaatg aggcagacat
     1141 tgctatttgc gatcctgctc attattatag tgaccgtcaa aacaatgatc ttaatatttt
     1201 ttatccggca tcaagcgtta aggtttacga aaaaacggaa gctctatgtg agatgtttta
     1261 tcaaaaatct tttttggtat ctgcttgggc taagatatat aaaaaggaac tatttgatga
     1321 tatcagattc cctgttggga agttatttga agatagtgct gttatgtatc tgctttttga
     1381 aaaatgtgaa aagatagtat attctaatgc gaaattatat gcctatgtgc atagagacaa
     1441 tagtattaca acaaagaagt tttcagataa agatttagat attttagaca tttcaaatac
     1501 tattcttgat cactatagtg ggaactttag agtttataaa gcggcagttt cctataaagt
     1561 ttcggcatgt tttagaattt tgttgaactc atcttcagaa aaaaaatata atcaaataca
     1621 aaaagattgt atgacatata ttttacgaaa ttggagaaat gtgttatttg ataaaaatgt
     1681 ccgattaaag aacaagcttg ccttgatttc tataactctt ttcaatcctt ttgttaaatt
     1741 tatctatagc aaagtaaaca gatgggaata atagcaaatg aacaaatatg aagaaagata
     1801 tcaggaagat ttatctaaga atgattttga gaaactaatc aatagaagat acctatcgga
     1861 taaagaacta caagttgaat atgtaaaaaa aggaacagtg ttacctccca aggtctttga
     1921 aatgaaacta tcaaataaac ttggtctaca aaaagctttg catgggaaag gtggtgttgt
     1981 agattcaaag gggaattatg ttgaactttc tgaacaaaaa gcagttggga tgagaaatcg
     2041 agtctatgga tcttacaaat ttaaccataa aaatttggct atcagaaatg aaaaagttat
     2101 ttacctaaac tatttcataa atcagtgggg acatttttta ctagatgttg tggggagatt
     2161 atggtatcca ttactaaaag atactgatac taaactggat tacacatgtt atgctggtac
     2221 agaaacgaaa cttgaaggaa actatttaga gtttttagaa ctcctcggta tagataaatc
     2281 acgcttaatt ttgataaatc gcccaactca attctcagag ataattatac ctgaaagttc
     2341 aattctgcca ggtgaatatt atacaaaaga atataaaatg ctttttaatt ctttagtagc
     2401 aaatgttaaa ttagataaca atttagaatc aaaaaaaatt tattgttcac gagctaggct
     2461 agatttagca aaaggtaaag agttcggtga gaatggtatt gaaaaggtct tcttaaaaaa
     2521 cggttatact ccagtttata tggaaacaat gtctttgaaa gaacaaataa gaacgctatt
     2581 atcagctaca acaatagtat taactagcgg ttcgttggct cataatttat tgtttataaa
     2641 caataaaatt aatgttttta ttttaaataa aacttataga gtaaatcttc accaattttt
     2701 aataaataaa atctcagaag ctagtgtgag ctttgtggat atttatcgtt ccccgttacc
     2761 tattttatat ggatatggtc catttttaat ggatattact aaacctttag tgaatttttt
     2821 tgaggacagt ggcttcacct at
//
LOCUS       DAVLXH010000100         2602 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00028199
            SAMN33607166-rid17955573.denovo.101, whole genome shotgun sequence.
ACCESSION   DAVLXH010000100 DAVLXH010000000
VERSION     DAVLXH010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607166
            Sequence Read Archive: SRR23725544
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2602)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2602)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721421.1
            Genome Coverage       :: 115x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:42:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,210
            CDSs (total)                      :: 2,161
            Genes (coding)                    :: 2,023
            CDSs (with protein)               :: 2,023
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 73 of 138
            Pseudo Genes (incomplete)         :: 60 of 138
            Pseudo Genes (internal stop)      :: 40 of 138
            Pseudo Genes (multiple problems)  :: 31 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2602
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607166-rid17955573.denovo.101"
                     /strain="AUSMDU00028199"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1349"
     gene            complement(<1..232)
                     /locus_tag="VYO11_002114"
     CDS             complement(<1..232)
                     /locus_tag="VYO11_002114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000005501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1596600.1"
                     /translation="MSEVDFNEAVTYEFTSDTCQLANSIYQSLFKFFDKKNFSGDLIF
                     TWKSPSLVKEGDYIGRRDSQVDNLRVIGNIFPN"
     gene            complement(290..1003)
                     /locus_tag="VYO11_002115"
     CDS             complement(290..1003)
                     /locus_tag="VYO11_002115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000499426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HEV1596601.1"
                     /translation="MFYKFLLFDLDHTLLDFDAAEDVALTQLLKEEGVADIQAYKDYY
                     VPMNKALWKDLELKKISKQELVNTRFSRLFAHFGQEKDGSFLAQRYQFYLAQQGQTLS
                     GAHDLLDSLIERDYNLYAATNGITAIQTGRLAQSGLAPYFNQVFISEQLQTQKPDALF
                     YEKIGQQIAEFSKEKTLMIGDSLTADIQGGNNAGIDTIWYNPHHLENHTQAQPTYEVY
                     SYQDLLDCLDKNILEKITF"
     gene            complement(1462..1842)
                     /locus_tag="VYO11_002116"
     CDS             complement(1462..1842)
                     /locus_tag="VYO11_002116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS-dependent dihydroxyacetone kinase
                     phosphotransferase subunit DhaM"
                     /protein_id="HEV1596602.1"
                     /translation="MESIGIGLVIVSHSKHIAEGVVELISKVAKDVPITYVGGTEGGG
                     IGTSFDQVDRVVSENPADTLLAFFDLGSAKMNLKMVTDFSDKSIIINRVPIVEGAYNA
                     AALLQAGAELSVIQIQLAELEINK"
     gene            complement(2264..>2602)
                     /locus_tag="VYO11_002117"
     CDS             complement(2264..>2602)
                     /locus_tag="VYO11_002117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine motif-containing protein"
                     /protein_id="HEV1596603.1"
                     /translation="KPSEEKPQTEKPEEETPREEKPQSEKPESPKPTEEPEESPEESE
                     EPQVETEKVEEKLREAEDLLGKIQDPIIKSNAKETLTGLKNNLLFGTQDNNTIMAEAE
                     KLLALLKESK"
BASE COUNT          796 a          513 c          415 g          878 t
ORIGIN      
        1 aattcggaaa tatatttcct attactctaa gattatctac ttgtgaatcc cttctcccaa
       61 tataatcccc ttctttgact aatgatggag atttccaagt aaaaattaaa tcgccagaga
      121 aatttttctt atcaaaaaac ttaaaaagag attgataaat actatttgct aattgacaag
      181 tgtcagatgt aaattcataa gtaacagctt cattaaaatc aacttcagac atttcaatgt
      241 actcttcaat agtaatatta gcttttttgt agtcattagc tcgtctcctt taaaatgtga
      301 tcttttcaag aatattttta tctaaacaat ccagcaagtc ttggtaagaa tagacttcgt
      361 aagtcggctg ggcttgtgtg tgattttcga ggtgatgagg attataccag atagtgtcaa
      421 tccccgcatt attgccacct tgaatgtcgg cagttagaga atctccaatc atcagcgtct
      481 tttctttact aaattcagca atttgctggc caatcttttc ataaaagaga gcatccggct
      541 tttgagtttg caactgttct gagataaaga cttgattgaa ataaggtgct agaccagatt
      601 gagccaaacg tcctgtctga atggcagtaa tgccatttgt cgcagcatac aagttataat
      661 cacgctcaat gaggctgtcc aagagatcat gagcgcccga tagtgtttgt ccctgctggg
      721 cgaggtaaaa ttggtaacgc tgggcaagaa aactaccgtc tttttcctgt ccaaaatgag
      781 caaataaacg agaaaagcgc gtgttaacca gctcttgttt actgattttc ttcagctcca
      841 agtctttcca gagagccttg ttcataggaa cgtaataatc tttataagcc tgaatatccg
      901 caactccttc ttcttttaga agttgggtca aagccacatc ctcagcagca tcaaaatcaa
      961 gaagagtgtg gtcgaggtcg aagagtagaa atttgtagaa caatttgagg ttttcctttc
     1021 tgaaaattca ttaagaacat tatatcataa agcacctcat acaattaact aatttaatca
     1081 cttaaaaaaa attcgaacac tttctataca actgacagct caaatctttc agaatagaac
     1141 aatactaact atcgagcacc ccgtcttcat aaatatatgt gtaattctag acctagaatt
     1201 cctataaact aaatgctttc atactcttcc aagtaattga ttgccttaaa ttttaatttt
     1261 tgaaggattc taaagctaga atagccccat cacaatcagt tttgattgat tcacaattta
     1321 gaaacactat agtttcactc ctgttaaaat aaaaaggaat tgcataaagc aatccctttc
     1381 tgattttgaa atcatttact taacatttta tagttgagat aatcaatagc ttacctataa
     1441 aaagagttat agtaaaattc cttatttatt gatttcaagc tccgctaact gtatttgaat
     1501 aactgacagt tctgcaccag cctgaagaag agcagctgca ttataggcac cttctacaat
     1561 tggaaccctg ttgatgatga tacttttatc actgaaatca gtcaccattt ttaagttcat
     1621 tttagcagaa cctaggtcaa aaaaggcaag taaagtatct gctggatttt cggaaacaac
     1681 cctatctact tgatcaaaac tcgttccaat tcctccgccc tcggttcctc ctacataagt
     1741 aatcggaaca tctttagcta ctttactaat cagttcaaca acaccttctg caatgtgttt
     1801 ggaatgtgaa acgataacaa gaccaatacc aatactttcc atcaaaccac tccagtttct
     1861 aaaatagcag taaagagtaa tcctgatgag aatgatccag gatcaatatg tccaagaaac
     1921 cacatgctcc taagacaaga gctaacagac tggccatcaa taatagtatt gttctttttt
     1981 tcatcattac tccttaacta gtgtttaact gattaattag ccagtaaata gtttatcttt
     2041 atttacacta tctgttaaga tatagtaaaa tgaaataaga acaggacagt caaatcgatt
     2101 tctaacaatg ttttagaagt agaggtatac tattctagtt tcaatctact atattttgca
     2161 cattttcatg aaaaaaatga gaactagaac tcacattctg ctctcatttt tcgttttccc
     2221 gttctcctat cctgttttta ggagttagaa aatgctgcta cctttactta ctctccttta
     2281 ataaagccaa tagtttttca gcttctgcca taatagtatt gttgtcctgg gtgccaaata
     2341 gtaaattatt ttttaatcct gtgagagtct ctttggcatt ggacttgata attggatcct
     2401 ggatttttcc aagtaaatct tcagcctctc tcagtttttc ttcaaccttt tcagtctcga
     2461 cctgaggttc ttctgattcc tctggtgatt cttctggttc ctctgttggt tttggagact
     2521 ctggtttctc gctttgcggt ttctcttctc gaggggtttc ttcctcaggt ttttctgtct
     2581 gaggtttctc ctcgcttggt tt
//
LOCUS       DAVLXH010000101         2588 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00028199
            SAMN33607166-rid17955573.denovo.102, whole genome shotgun sequence.
ACCESSION   DAVLXH010000101 DAVLXH010000000
VERSION     DAVLXH010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607166
            Sequence Read Archive: SRR23725544
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2588)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2588)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721421.1
            Genome Coverage       :: 115x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:42:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,210
            CDSs (total)                      :: 2,161
            Genes (coding)                    :: 2,023
            CDSs (with protein)               :: 2,023
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 73 of 138
            Pseudo Genes (incomplete)         :: 60 of 138
            Pseudo Genes (internal stop)      :: 40 of 138
            Pseudo Genes (multiple problems)  :: 31 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2588
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607166-rid17955573.denovo.102"
                     /strain="AUSMDU00028199"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1349"
     gene            complement(<1..71)
                     /gene="ffs"
                     /locus_tag="VYO11_002118"
     ncRNA           complement(<1..71)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="VYO11_002118"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            complement(104..571)
                     /locus_tag="VYO11_002119"
     CDS             complement(104..571)
                     /locus_tag="VYO11_002119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deaminase"
                     /protein_id="HEV1596604.1"
                     /translation="MYYTLEEKEVFMREALREAEIALEHDEIPIGCVIVKDGEIIGRG
                     HNAREELQRAVMHAEIMAIEDANLSEESWRLLDCTLFVTIEPCVMCSGAIGLARIPNV
                     VYGAKNQKFGAAGSLYDILTDERLNHRVEVEIGILEDECAAIMQDFFRNRRKK"
     gene            complement(772..2058)
                     /locus_tag="VYO11_002120"
     CDS             complement(772..2058)
                     /locus_tag="VYO11_002120"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HEV1596605.1"
                     /translation="MTSVVVVGTQWGDEGKGKITDFLSANAEVIARYQGGDNAGHTIV
                     IDGKKFKLHLIPSGIFFPEKISVIGNGMVVNPKSLVKELSYLHEEGVTTDNLRISDRA
                     HVILPYHIELDRLQEEAKGDNKIGTTIKGIGPAYMDKAARVGIRIADLLDKDIFRERL
                     ERNLAEKNRLFEKLYDSKAIVFDDIFEEYYEYGQQIKKYVIDTSVILNDALDNGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGIGPSKIDKVVGVCKAYTSRVGDGP
                     FPTELFDEVGERIREVGHEYGTTTGRPRRVGWFDSVVMRHSRRVSGITNLSLNSIDVL
                     SGLDTVKICVAYDLDGQRIDYYPASLEQLKRCKPIYEELPGWSEDITGVRNLEDLPEN
                     ARNYVRRVSELVGVRISTFSVGPGREQTNILESVWS"
     gene            complement(2289..2525)
                     /locus_tag="VYO11_002121"
     CDS             complement(2289..2525)
                     /locus_tag="VYO11_002121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecX"
                     /protein_id="HEV1596606.1"
                     /translation="MLQKIYEQMANFYDSIEEEYGPTFGDNFDWEHVHFKFLIYYLVR
                     YGIGCRKDFIVYHYRVAYRLYLEKLVMNRGFISC"
BASE COUNT          855 a          631 c          353 g          749 t
ORIGIN      
        1 tcaaatcgct tagggctgct ggattcctcc cctgacccgc ttcacgcaga actgttgctc
       61 cactatttat tatatcacat tcctattcat tttaaaagca aaattatttt ttccgtctat
      121 ttctaaaaaa atcctgcatg atagctgcgc attcatcttc caaaattcct atttcaacct
      181 ccacacgatg attgagacgc tcatctgtca agatatcgta caaactccca gcagcgccaa
      241 atttctggtt tttagcccca tagaccacat ttggaatgcg ggcaagccca atcgccccac
      301 tacacatgac acaaggttca atggtcacaa aaagtgtgca atccagcaag cgccagctct
      361 cctcactcaa gttcgcatcc tctatagcca taatttccgc atgcataacc gctcgctgta
      421 attcctcacg cgcattatgc ccacgaccaa tgatttcccc atctttgaca atcacacaac
      481 caattggaat ttcatcgtgt tcaagagcaa tctcagcctc tctcaaagcc tccctcataa
      541 agacttcttt ttcttcaagc gtataataca tctcttttct cttttcctac ttatcgattt
      601 tattattata tcatgaatcc caacacaaaa aaagccaccg aatgcggtga ctctataggg
      661 agattattat gaaaaagaaa agtttaggat atttgttaca acaagttagg aggtcttctt
      721 gtaaccgtct atagtatacc cgacctatct taaacaaatc ttaaaaatct cttaggacca
      781 aacactttct aaaatatttg tttgttcacg accaggacct actgagaaag tagaaatacg
      841 aacgccaacc aattcactca cacgacgaac atagttacgc gcattctcag gaagatcttc
      901 caaattgcga actccggtaa tatcttctga ccaacctggc aactcttcat agataggctt
      961 gcaacgtttc aattgctcaa gactagctgg atagtagtca atacgttgac cgtcaagatc
     1021 ataggccaca cagattttca cagtatccaa accgctcaaa acatcaatag agttcaaaga
     1081 aaggttagta ataccagaaa cacgacggct atgacgcatc acaactgagt caaaccaacc
     1141 tacacgacgt ggacgaccag ttgttgtacc atattcatga cccacttcac ggatacgttc
     1201 tcccacttca tcaaacaact cagttgggaa aggaccatct cctacacgac tcgtataagc
     1261 tttacataca cctacaacct tgtcaatctt gcttggaccg ataccagaac caattgtcac
     1321 accaccagct acagggtttg atgacgtaac aaatggataa gtaccttggt cgatatctag
     1381 cataacacct tgtgcacctt caaaaagcac acgtttgcca ttatcaagcg catcattcaa
     1441 gataacagat gtatctatca cgtatttctt gatttgttga ccatattcgt aatattcttc
     1501 aaaaatatca tcgaaaacaa tcgctttact gtcatacaat ttttcaaaaa gacgattctt
     1561 ttcagcaagg ttacgttcta aacgctcacg gaaaatatct ttatctaaaa gatctgcaat
     1621 acgaattcca acacgagcag ccttgtccat ataagctgga ccaattccct taattgtcgt
     1681 accaatctta ttgtcgccct tagcttcttc ttgcaagcga tccaactcga tatgataagg
     1741 caaaataaca tgcgcacgat cagaaatacg caagttatca gttgttacac cttcctcatg
     1801 aagatagctc aactctttta caagagattt aggatttaca accataccat tcccaatgac
     1861 agatattttt tcagggaaga aaatcccaga tggaatcaag tgcaacttaa atttcttacc
     1921 gtcaatcaca atcgtgtgac cagcattatc accaccttgg taacgtgcaa tcacttctgc
     1981 attcgctgaa aggaagtctg taatcttccc tttaccttca tcaccccatt gggtacctac
     2041 aacaacaact gaagtcataa tcttgtctga gccctcaggc tcttcctttc tcacatacat
     2101 ggcaggactc tcacctgcaa ttatatctta caatttatta taataaaaaa tcgccttttt
     2161 atcaagaaga aacaatagaa agatttgcta tttccaacta ttaaaaaatg atttagaaaa
     2221 attactagct atttactatt atctttccat aaaagagtaa attagttcgg aaatttacta
     2281 aaattacctc aacaagaaat aaaaccccga ttcattacca atttttcaag atacaaacga
     2341 taagcaacac gataatggta aacgataaaa tccttacgac aaccaatgcc atatctcact
     2401 aaataataaa ttaaaaattt aaaatgaaca tgttcccagt caaaattatc accaaatgta
     2461 ggaccatact cttcttcaat actatcatag aaattagcca tctgctcata aattttttgt
     2521 aacataatca aatactcctt ttctttttta taaacttatt ctaacaaaaa attttacaca
     2581 ttcactat
//
LOCUS       DAVLXH010000102         2577 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00028199
            SAMN33607166-rid17955573.denovo.103, whole genome shotgun sequence.
ACCESSION   DAVLXH010000102 DAVLXH010000000
VERSION     DAVLXH010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607166
            Sequence Read Archive: SRR23725544
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2577)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2577)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721421.1
            Genome Coverage       :: 115x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:42:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,210
            CDSs (total)                      :: 2,161
            Genes (coding)                    :: 2,023
            CDSs (with protein)               :: 2,023
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 73 of 138
            Pseudo Genes (incomplete)         :: 60 of 138
            Pseudo Genes (internal stop)      :: 40 of 138
            Pseudo Genes (multiple problems)  :: 31 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2577
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607166-rid17955573.denovo.103"
                     /strain="AUSMDU00028199"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1349"
     gene            complement(1..729)
                     /locus_tag="VYO11_002122"
                     /pseudo
     CDS             complement(1..729)
                     /locus_tag="VYO11_002122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="programmed frameshift; internal stop; incomplete;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(674..856)
                     /locus_tag="VYO11_002123"
     CDS             complement(674..856)
                     /locus_tag="VYO11_002123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEV1596607.1"
                     /translation="MDLKFEGVDLEYKKAKNNLPESFWETYSAFANTNGGKIILGIDE
                     KNIDTYQRVNRLPAKL"
     gene            1191..>2577
                     /gene="pcpA"
                     /locus_tag="VYO11_002124"
     CDS             1191..>2577
                     /gene="pcpA"
                     /locus_tag="VYO11_002124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000753868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein PcpA"
                     /protein_id="HEV1596608.1"
                     /translation="MKKTTILSLTTAAVILAAYVPNEPILADTPSSEVIKETKVGSII
                     QQNNIKYKVLTVEGNIGTVQVGNGVTPVEFEAGQDGKPFTIPTKITVGDKVFTVTEVA
                     SQAFSYYPDETGRIVYYPSSITIPSSIKKIQKKGFHGSKAKTIIFDKGSQLEKIEDRA
                     FDFSELEEIELPASLEYIGTSAFSFSQKLKKLTFSSSSKLELISHEAFANLSNLEKLT
                     LPKSVKTLGSNLFRLTTSLKHVDVEEGNESFASVDGVLFSKDKTQLIYYPSQKNDESY
                     KTPKETKELASYSFNKNSYLKKLELNEGLEKIGTFAFADAIKLEEISLPNSLETIERL
                     AFYGNLELKELILPDNVKNFGKHVMNGLPKLKSLTIGNNINSLPSFFLSGVLDSLKEI
                     HIKNKSTEFSVKKDTFAIPETVKFYVTSEHIKDVLKSNLSTSNDIIVEKVDNIKQETD
                     VAKPKKNSNRGV"
BASE COUNT          873 a          404 c          428 g          872 t
ORIGIN      
        1 ttctcaacct tgcttctctc cttggatagc gcatggttat aggctttatc ttcagctgtt
       61 agtggcttga gtttgctgga tttacgtgaa gtttgtgctt gaggacatat cttcatgagc
      121 ccttgataac cactgtcagc caagatttta ccaacttgtc tgatatttct gcaactcatt
      181 ttgaacaact tcatatcatg acaatagttc acagtgatat ccaaagaaac aattctccct
      241 tgacttgtga caatcgcttg agccttcata gcgtgaaatt tctttttacc agaatgattc
      301 gctaattgtt tttttagggc gattgatttg tacttccgtc gcatcaatca ttaccgtgtc
      361 ctcagagctg agaggagttc ttgaaatcgt aacaccactt tgaacaagag ttacttcaac
      421 ccattggctc cgacggatta agttgctttc gtggatacca aaatcagccg caatttcttc
      481 ataagtgcgg tattctcaca catattgaag agtggccata agaaggtctt ctaggcttaa
      541 tttaggtttt cgtccacctt ttgcgtgttt aagttgataa gctgttttta atacagctaa
      601 catctcttta aaagtcgtgc gctgaacacc aacaagacgc ttaaatcgtg tatcagttaa
      661 ttgtttactt gcttcataat ttcgcaggga gtctattgac tctttggtag gtgtcaatgt
      721 ttttttcatc tatcccgaga attattttcc cgccatttgt atttgcaaat gctgagtagg
      781 tttcccagaa agactctgga agattgtttt tagctttttt gtattctaaa tcaacccctt
      841 caaattttaa gtccatattt ttcctttaca tctgtttttt gtggttctgg tatttgttca
      901 agttgagtga taatatagcg aattgaattt cgagagtttt tactcagtta atttcttttt
      961 taacccactt taatttcttt tttaacgcgg gttaaaaaag aaattaaagt gggttaattt
     1021 tccttgactt aaaatttaaa aatgatatac tgtgtttatg gagagatgac aatttataaa
     1081 atgtactact ctattctact agataatgat tgaataaaac tttttataac aacggctagc
     1141 aaagttataa ttttatatct attagaaaat aaatatgtaa ggaaatttaa atgaaaaaaa
     1201 ctacaatatt atcattaact acagctgcgg ttattttagc agcatatgtc cctaatgaac
     1261 caatcctagc agatactcct agttcggaag taatcaaaga gactaaagtt ggaagtatta
     1321 ttcaacaaaa taatatcaaa tataaggttc taactgtaga aggtaacata ggaactgttc
     1381 aagtgggtaa tggagttact cctgtagagt ttgaagctgg tcaagatgga aaaccattca
     1441 cgattcctac aaaaatcaca gtaggtgata aagtatttac cgttactgaa gtagctagtc
     1501 aagcttttag ttattatcca gatgaaacag gtagaattgt ctactatcct agctctatta
     1561 ctatcccatc aagcataaaa aaaatacaaa aaaaaggctt ccatggaagt aaagctaaaa
     1621 ctattatttt tgacaaaggc agtcagctgg agaaaattga agatagagct tttgattttt
     1681 ctgaattaga agagattgaa ttgcctgcat ctctagaata tattggaaca agtgcatttt
     1741 cttttagtca aaaattgaaa aagctaacct tttcctcaag ttcaaaatta gaattaatat
     1801 cacatgaggc ttttgctaat ttatcaaatt tagagaaact aacattacca aaatcggtta
     1861 aaacattagg aagtaatcta tttagactca ctactagctt aaaacatgtt gatgttgaag
     1921 aaggaaatga atcgtttgcc tcagttgatg gtgttttgtt ttcaaaagat aaaactcaat
     1981 taatttatta tccaagtcaa aaaaatgacg aaagttataa aacgcctaaa gagacaaaag
     2041 aacttgcatc atattcgttt aataaaaatt cttacttgaa aaaactcgaa ttgaatgaag
     2101 gtttagaaaa aatcggtact tttgcatttg cggatgcgat taaacttgaa gaaattagct
     2161 taccaaatag tttagaaact attgaacgtt tagcctttta cggtaattta gaattaaaag
     2221 aacttatatt accagataat gttaaaaatt ttggtaaaca cgttatgaac ggtttaccaa
     2281 aattaaaaag tttaacaatt ggtaataata tcaactcatt gccgtccttc ttcctaagtg
     2341 gcgtcttaga ttcattaaag gaaattcata ttaagaataa aagtacagag ttttctgtga
     2401 aaaaagatac atttgcaatt cctgaaactg ttaagttcta tgtaacatca gaacatataa
     2461 aagatgttct taaatcaaat ttatctacta gtaatgatat cattgttgaa aaagtagata
     2521 atataaaaca agaaactgat gtagctaaac ctaaaaagaa ttctaatcgg ggagtag
//
LOCUS       DAVLXH010000103         2360 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00028199
            SAMN33607166-rid17955573.denovo.104, whole genome shotgun sequence.
ACCESSION   DAVLXH010000103 DAVLXH010000000
VERSION     DAVLXH010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607166
            Sequence Read Archive: SRR23725544
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2360)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2360)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721421.1
            Genome Coverage       :: 115x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:42:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,210
            CDSs (total)                      :: 2,161
            Genes (coding)                    :: 2,023
            CDSs (with protein)               :: 2,023
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 73 of 138
            Pseudo Genes (incomplete)         :: 60 of 138
            Pseudo Genes (internal stop)      :: 40 of 138
            Pseudo Genes (multiple problems)  :: 31 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2360
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607166-rid17955573.denovo.104"
                     /strain="AUSMDU00028199"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1349"
     gene            <1..201
                     /locus_tag="VYO11_002125"
     CDS             <1..201
                     /locus_tag="VYO11_002125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein A"
                     /protein_id="HEV1596609.1"
                     /translation="NANGSMATGWLKDGDTWYYLEASGAMKESQWFKVSDKWYYVNGS
                     GALAVNTTVGGYRVNANGKWVN"
     gene            541..>2360
                     /locus_tag="VYO11_002126"
     CDS             541..>2360
                     /locus_tag="VYO11_002126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RICH domain-containing protein"
                     /protein_id="HEV1596610.1"
                     /translation="MFKSNHERRMRYSIRKFSVGVASVAVASLFMGSVVHATEKEGST
                     QAATSSNMAKTEHRKAAKQFDEYINKMIQLDRRKDTQNRTLIIKLSAIKTKYLRELNV
                     LEEKSKDELPPKIKEELTAAFEQFKKDTLSTEPEKKVAEAKKKVEEAKKKAEDQKEKD
                     RRNYPTITYKTLELEIAESDVEVKKAELELVKVKANEPRDEEKIKQAEAKVESKQAEA
                     TRLKKIKTDREQAEATRLENIKTDREQAEEEAKVKDEPKKRTKRGVLGELATPDKKEN
                     DAKSSDSSVGEETLPSPSLKPEKKVAEAEKKVEEAKKKAEDQKEEDRRNYPTNTYKTL
                     ELEIAESDVEVKKAELELVKEEAKEPRNEEKVKQAKAEVESKQAEATRLEKIKTDRKK
                     AEEEAKRKAEESEKKAAEAKQKVDAEEYALEAKIAELEYEVQRLEKELKEIDESDSED
                     YLKEGLRAPLQSKLDTKKAKLSKLEELSDKIDELDAEIAKLEVQLKDAEGNNNVEAYF
                     KEGLEKTTAEKKAELEKAEADLKKAVDEPETPAPAPQPAPAPEKPAEKPAPAPAPEKP
                     APAPEKPAPTPETPKTGWKQENGMWYFYNTDGSMATGWLQ"
BASE COUNT          952 a          392 c          514 g          502 t
ORIGIN      
        1 aatgctaacg gttcgatggc aacaggttgg ctgaaagatg gagatacatg gtactatctt
       61 gaagcatcag gggctatgaa agaaagccaa tggttcaaag tatcagacaa atggtactat
      121 gtcaatggct caggtgccct tgcagtcaac acaactgtag gtggctatag agtcaatgcc
      181 aatggtaaat gggtaaacta aacctaatgt aactcgttaa tgctggcttc ctgtaagaac
      241 tctttaaagt attccctaca aataccatat cctttcagta gatactatac ccttgtagga
      301 agtttagatt aaaaaataac tctgtaatct ctagccggat ttatggcgct agagactacg
      361 gagtttaatt tctgttgaat tctagtttca ttagaatagc agaggaagaa aaattattgc
      421 aggaagttat tattccaaat ggaagaataa aaggatagcg aaaataatgt agcaaatttc
      481 atatacaatt catattagca ggatatactg tagttaatta aaattatgga gaatatagac
      541 atgtttaaat caaatcatga gcgaagaatg cgttattcca ttcgtaaatt tagtgtagga
      601 gtagctagtg tagctgttgc cagtcttttt atgggaagtg tggttcatgc gacagagaaa
      661 gagggaagta cccaagcagc cacttcttct aatatggcaa agacagaaca taggaaagct
      721 gctaaacaat tcgatgaata tataaacaaa atgatccaat tagatagaag aaaagatacc
      781 caaaatcgca ccttaatcat aaagttgagc gcaattaaaa cgaagtattt gcgtgaatta
      841 aatgttttag aagagaagtc gaaagatgag ttgccgccaa aaataaaaga agagttaacc
      901 gcagcttttg agcagtttaa aaaagataca ttatcaacag aaccagaaaa aaaggtagca
      961 gaagctaaga agaaggttga agaagctaag aaaaaagccg aggatcaaaa agaaaaagat
     1021 cgccgtaact acccaaccat tacttacaaa acgcttgaac ttgaaattgc tgagtccgat
     1081 gtggaagtta aaaaagcgga gcttgaacta gtaaaagtga aagctaacga acctcgagac
     1141 gaggaaaaaa ttaagcaagc agaagcgaaa gttgagagta aacaagctga ggctacaagg
     1201 ttaaaaaaaa tcaagacaga tcgtgaacaa gctgaggcta caaggttaga aaacatcaag
     1261 acagatcgtg aacaagcaga agaagaagct aaagttaaag atgaaccaaa gaagcggaca
     1321 aaacgaggag ttcttggaga gctagcaaca cctgataaaa aagaaaatga tgcgaagtct
     1381 tcagattcta gcgtaggtga agaaactctt ccaagcccat ccctgaaacc agaaaaaaag
     1441 gttgcagaag ctgagaagaa ggttgaagaa gctaagaaaa aagccgagga tcaaaaagaa
     1501 gaagatcgtc gtaactaccc aaccaatact tacaaaacgc ttgaacttga aattgctgag
     1561 tccgatgtgg aagttaaaaa agcggagctt gaactagtaa aagaggaagc taaggaacct
     1621 cgaaacgagg aaaaagttaa gcaagcaaaa gcggaagttg agagtaaaca agctgaggct
     1681 acaaggttag aaaaaatcaa gacagatcgt aaaaaagcag aagaagaagc taaacgaaaa
     1741 gcagaagaat ctgagaaaaa agctgctgaa gccaaacaaa aagtggatgc tgaagaatat
     1801 gctcttgaag ctaaaatcgc tgagttggaa tatgaagttc agagactaga aaaagagctc
     1861 aaagagattg atgagtctga ctcagaagat tatcttaaag aaggcctccg tgctcctctt
     1921 caatctaaat tggataccaa aaaagctaaa ctatcaaaac ttgaagagtt gagtgataag
     1981 attgatgagt tagacgctga aattgcaaaa cttgaagttc aacttaaaga tgctgaagga
     2041 aacaataatg tagaagccta ctttaaagaa ggtttagaga aaactactgc tgagaaaaaa
     2101 gctgaattag aaaaagctga agctgacctt aagaaagcag ttgatgagcc agaaactcca
     2161 gctccggctc ctcaaccagc tccagctcca gaaaaaccag ctgaaaaacc agctccagct
     2221 ccagctccag aaaaaccagc tccagctcca gaaaaaccag ctccaactcc agaaactcca
     2281 aaaacaggct ggaaacaaga aaacggtatg tggtacttct acaatactga tggttcaatg
     2341 gcaacaggct ggctccaaaa
//
LOCUS       DAVLXH010000104         2190 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00028199
            SAMN33607166-rid17955573.denovo.105, whole genome shotgun sequence.
ACCESSION   DAVLXH010000104 DAVLXH010000000
VERSION     DAVLXH010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607166
            Sequence Read Archive: SRR23725544
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2190)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2190)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721421.1
            Genome Coverage       :: 115x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:42:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,210
            CDSs (total)                      :: 2,161
            Genes (coding)                    :: 2,023
            CDSs (with protein)               :: 2,023
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 73 of 138
            Pseudo Genes (incomplete)         :: 60 of 138
            Pseudo Genes (internal stop)      :: 40 of 138
            Pseudo Genes (multiple problems)  :: 31 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2190
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607166-rid17955573.denovo.105"
                     /strain="AUSMDU00028199"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1349"
     gene            <1..627
                     /locus_tag="VYO11_002127"
     CDS             <1..627
                     /locus_tag="VYO11_002127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HEV1596611.1"
                     /translation="ITMDMFSPYYDLARQLFPCAKIVLDRFHIVQHLSRAMSRVRVQI
                     MNQFHRKSHEYKAIKRYWKLIQQDSRKLSDKRFYRPTFRMHLTNKEILNKLLSYSEDL
                     KHHYQLLLFHFQNKEPEKFFELIEDNLKQVHPIFQTVFKTFLKDKEKIINALQLPYSN
                     AKLEATNNLIKLIKRNAFGFRNFENFKKRIFIALNIKKERTKFVLSRA"
     gene            complement(761..848)
                     /locus_tag="VYO11_002128"
     tRNA            complement(761..848)
                     /locus_tag="VYO11_002128"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(812..814),aa:Ser,seq:gct)
     gene            complement(855..928)
                     /locus_tag="VYO11_002129"
     tRNA            complement(855..928)
                     /locus_tag="VYO11_002129"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(892..894),aa:Ile,seq:gat)
     gene            complement(964..1034)
                     /locus_tag="VYO11_002130"
     tRNA            complement(964..1034)
                     /locus_tag="VYO11_002130"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1000..1002),aa:Gly,seq:tcc)
     gene            complement(1054..1126)
                     /locus_tag="VYO11_002131"
     tRNA            complement(1054..1126)
                     /locus_tag="VYO11_002131"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1091..1093),aa:Phe,seq:gaa)
     gene            complement(1130..1203)
                     /locus_tag="VYO11_002132"
     tRNA            complement(1130..1203)
                     /locus_tag="VYO11_002132"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1167..1169),aa:Met,seq:cat)
     gene            complement(1217..1306)
                     /locus_tag="VYO11_002133"
     tRNA            complement(1217..1306)
                     /locus_tag="VYO11_002133"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1268..1270),aa:Ser,seq:tga)
     gene            complement(1317..1390)
                     /locus_tag="VYO11_002134"
     tRNA            complement(1317..1390)
                     /locus_tag="VYO11_002134"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1354..1356),aa:Ile,seq:cat)
     gene            complement(1404..1477)
                     /locus_tag="VYO11_002135"
     tRNA            complement(1404..1477)
                     /locus_tag="VYO11_002135"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1441..1443),aa:Met,seq:cat)
     gene            complement(1483..1556)
                     /locus_tag="VYO11_002136"
     tRNA            complement(1483..1556)
                     /locus_tag="VYO11_002136"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1520..1522),aa:Pro,seq:tgg)
     gene            complement(1572..1645)
                     /locus_tag="VYO11_002137"
     tRNA            complement(1572..1645)
                     /locus_tag="VYO11_002137"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1609..1611),aa:Arg,seq:acg)
     gene            complement(1655..1740)
                     /locus_tag="VYO11_002138"
     tRNA            complement(1655..1740)
                     /locus_tag="VYO11_002138"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1704..1706),aa:Leu,seq:taa)
     gene            complement(1748..1819)
                     /locus_tag="VYO11_002139"
     tRNA            complement(1748..1819)
                     /locus_tag="VYO11_002139"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1785..1787),aa:Gly,seq:gcc)
     gene            complement(1842..1914)
                     /locus_tag="VYO11_002140"
     tRNA            complement(1842..1914)
                     /locus_tag="VYO11_002140"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1879..1881),aa:Thr,seq:tgt)
     gene            complement(1933..2014)
                     /locus_tag="VYO11_002141"
     tRNA            complement(1933..2014)
                     /locus_tag="VYO11_002141"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1978..1980),aa:Leu,seq:tag)
     gene            complement(2020..2092)
                     /locus_tag="VYO11_002142"
     tRNA            complement(2020..2092)
                     /locus_tag="VYO11_002142"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(2057..2059),aa:Lys,seq:ttt)
     gene            complement(2117..2189)
                     /locus_tag="VYO11_002143"
     tRNA            complement(2117..2189)
                     /locus_tag="VYO11_002143"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(2154..2156),aa:Asp,seq:gtc)
BASE COUNT          644 a          563 c          435 g          548 t
ORIGIN      
        1 attactatgg atatgtttag tccttactat gacttagcta gacaactttt cccatgtgct
       61 aaaatcgtgt tggatcgctt tcacattgta caacatctta gccgtgctat gagtcgtgtg
      121 cgtgttcaaa tcatgaatca gtttcatcga aaatcccatg aatacaaggc tatcaagcgc
      181 tactggaagc tcatacaaca ggatagtcgt aaactgagtg ataagcgatt ttatcgtcct
      241 acttttcgta tgcacttaac caataaagag attttaaaca agcttttgag ttattcggaa
      301 gacttgaaac accactatca gctcttactt tttcacttcc agaataagga accagagaaa
      361 tttttcgaac ttattgagga caatcttaag caggttcatc ctatttttca gactgtcttt
      421 aaaaccttcc tcaaagataa agaaaagatt attaacgccc ttcaactacc ctattctaat
      481 gccaaactgg aagcgaccaa taatctcatc aaacttatca agcgcaatgc ctttggattt
      541 cggaactttg aaaacttcaa aaaacggatt ttcatcgctt tgaacatcaa aaaagaaagg
      601 acaaaatttg tcctttctcg agcttagctt ttcttcaacc cactacagtt gacaaagagc
      661 cataaaaata acttcagatt agtaattcaa ttaagtttta cggatctgaa gctttattgt
      721 ctctaaaaat aaaaaagaga gttacaaact ctcattaaaa cggagaataa gggattcgaa
      781 cccttgcgcc agttacccga cctaacgatt tagcaaaccg tcctcttcag cctcttgagt
      841 aattctccaa ttaatgggca cgagtggact cgaaccaccg acctcacgct tatcaggcgt
      901 gcgctctaac cacctgagct acgcgcccaa gttaaaaaac ttggtaattt gaacaaagtt
      961 caaagcgggt gacgagaatc gaactcgcga caacagcttg gaaggctgta gttttaccac
     1021 taaactacac ccgcataaat actatcaata aaatggcgcg agacggaatc gaaccgccga
     1081 cacatggagc ttcaatccat tgctctacca actgagctac cgagccttat tgcgggagca
     1141 ggatttgaac ctacgacctt cgggttatga gcccgacgag ctaccgagct gctccatccc
     1201 gcgttaataa tataaaagga ggatgtggga ttcgaaccca cgcacgcttt tacacgcctg
     1261 acggttttca agaccgttcc cttcagccgg acttgggtaa tcctccaata ttcaaatgga
     1321 ccttgtagga cttgaaccta cgaccactcg gttatgagcc gagagctcta accagctgag
     1381 ctaaaggtcc aacaagatca ttatagcggc gaaggggatc gaacccccga cctcccgggt
     1441 atgaaccgga cgctctagcc agctgagcta caccgccatg aatcgggaag acaggattcg
     1501 aacctgcgac accttggtcc caaaccaagt actctaccaa gctgagctac ttcccgagtt
     1561 aaatagaaaa atgcacccta gaggagtcga acctctaacc gcctgattcg tagtcaggta
     1621 ctctatccag ttgagctaag ggtgctccat attatgccga ggaccggaat cgaaccggta
     1681 cgatcgttac caatcgcagg attttaagtc ctgtgcgtct gccagttccg ccaccccggc
     1741 ctctctaagc gaacgacggg attcgaaccc gcgaccccca ccttggcaag gtggtgttct
     1801 accactgaac tacgttcgca ctgttttctt ctatctaaaa atgccggcta catgacttga
     1861 acacgcgacc ctctgattac aaatcagatg ctctaccaac tgagctaagc cggctcattt
     1921 gttatatctt aatgcgggtt aagggacttg aacccccacg ccgttaagcg ccagatccta
     1981 aatctggtgc gtctgccaat tccgccaaac ccgcatatat gacccgtact gggctcgaac
     2041 cagtgaccca ttgattaaaa gtcaattgct ctaccaactg agctaacgag tctaaaataa
     2101 cttgcgttac cttaaacggt cccgacggga atcgaacccg cgatcttcgc cgtgacaggg
     2161 cgacgtgata accgctacac tacgggacct
//
LOCUS       DAVLXH010000105         1922 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00028199
            SAMN33607166-rid17955573.denovo.106, whole genome shotgun sequence.
ACCESSION   DAVLXH010000105 DAVLXH010000000
VERSION     DAVLXH010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607166
            Sequence Read Archive: SRR23725544
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1922)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1922)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721421.1
            Genome Coverage       :: 115x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:42:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,210
            CDSs (total)                      :: 2,161
            Genes (coding)                    :: 2,023
            CDSs (with protein)               :: 2,023
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 73 of 138
            Pseudo Genes (incomplete)         :: 60 of 138
            Pseudo Genes (internal stop)      :: 40 of 138
            Pseudo Genes (multiple problems)  :: 31 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1922
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607166-rid17955573.denovo.106"
                     /strain="AUSMDU00028199"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1349"
     gene            complement(47..166)
                     /locus_tag="VYO11_002144"
     CDS             complement(47..166)
                     /locus_tag="VYO11_002144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000346296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HEV1596612.1"
                     /translation="MDFKSFIIGLVVGIFGPYMDDLIRKIFSKSSKKDTDSTL"
     gene            complement(270..419)
                     /gene="blpO"
                     /locus_tag="VYO11_002145"
     CDS             complement(270..419)
                     /gene="blpO"
                     /locus_tag="VYO11_002145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpO"
                     /protein_id="HEV1596613.1"
                     /translation="MDTKMMSQFAVMDNEMLACVEGGDIDWGRKISCAAGVAYGAIDG
                     CATTV"
     gene            complement(663..866)
                     /gene="blpN"
                     /locus_tag="VYO11_002146"
     CDS             complement(663..866)
                     /gene="blpN"
                     /locus_tag="VYO11_002146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit BlpN"
                     /protein_id="HEV1596614.1"
                     /translation="MNTYCNINETMLSEVYGGNSGGAAVVAALGCAAGGVKYGRLLGP
                     WGAAIGGIGGAVVCGYLAYTATS"
     gene            complement(882..1136)
                     /gene="blpM"
                     /locus_tag="VYO11_002147"
     CDS             complement(882..1136)
                     /gene="blpM"
                     /locus_tag="VYO11_002147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000379879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit BlpM"
                     /protein_id="HEV1596615.1"
                     /translation="MNTKMMEQFHEMDITMLSSIEGGKNNWQTNVLEGGGAAFGGWGL
                     GTAICAASGVGAPFMGACGYIGAKFGVDLWAGVTGATGGF"
     gene            complement(1280..1922)
                     /locus_tag="VYO11_002148"
                     /pseudo
     CDS             complement(1280..1922)
                     /locus_tag="VYO11_002148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="IS5 family transposase"
BASE COUNT          601 a          429 c          268 g          624 t
ORIGIN      
        1 ctcccctgta aattaagcta gcaaatacag gggagaaatt tattttttag agagtactat
       61 ccgtatcctt tttggaagat tttgaaaata tttttctaat taagtcatcc atataaggac
      121 caaatatacc aactactaaa ccaataataa aacttttaaa atccataatt accaccaaca
      181 tattgctgca taggctacac ctccaagtat agctccacct gcagcaccag ctacacctat
      241 tcctatagca aatggtccca atagaaatgt caaaccgttg ttgcacaccc atcaattgcg
      301 ccatatgcaa cccctgctgc acaactaatt tttcttcccc aatcaatatc tccaccttca
      361 acgcaagcaa gcatttcatt atccataact gcaaattgtg acatcatttt tgtatccata
      421 tagtatatca cttttcagtt acggaacaag tttaatataa aaattatcaa aaaaacatag
      481 gcaataaaga gaaaaattaa tttatcatag attagaaata atatgacaaa acaattcaat
      541 gatgttaatt caatagtctt ttgtttttta tcggagatac ttatggatag ataaataaga
      601 taggtttgaa aagcgaagag aataataaag aatatagcct tcataaaatt tagctttcat
      661 ttttatgatg tagcggtata ggctaaatat ccacaaacca ctgctcctcc aattcctcct
      721 attgcagcgc cccatggtcc tagaagtctc ccatatttca ctccacccgc tgcacaacct
      781 aaagcagcaa ctacagctgc tcctccggaa ttacctccat aaacctcact cagcattgtt
      841 tcatttatat tacaataagt attcatacaa gtctcctttt attaaaatcc acccgttgcc
      901 cctgttactc ctgcccaaag atccacacca aatttagctc ctatgtatcc acatgctccc
      961 ataaatggtg ctccaacacc actcgcagca caaatagctg tccctagccc ccagccacca
     1021 aaagcagcac caccaccttc taagacatta gtttgccaat tattcttgcc tccttcaata
     1081 ctagataaca tagttatatc catttcatga aattgttcca tcatttttgt attcataaca
     1141 aatactcctt ttttattttt gtcttgttgc aactttgaca agtttagtat atcattgttt
     1201 tttaaaattt ttcatccaaa tcttgaattg tcatcgaaac gtcttgaatt gcaaaaatta
     1261 cattagactt cctgcaaaac tagaatccta gttcatgatt gataatgcca gcaatcaaat
     1321 tcattcgtaa tccgaagcgt ttacgatgat ttcgataggt tgttgaaaac attttaaacg
     1381 tttttacttt ggcaaggatg ctctcaacct tgcttctctc cttagataac gcatggttat
     1441 aggctttatc tttaactgtt agcggtttga gtttgctgga tttacgtgga gtttgtgctt
     1501 gaggatatat cttcatgagc ccttgataat tactgtcagc caaggtttta ccagtttgtc
     1561 caatatttct gcgactcatt ttgaacaact tcatatcgtg gcaatagttc acagtgatat
     1621 ccaaagaaac aattctccct tgacttgtga caatcgcttg agccttcata gcgtgaaatt
     1681 tctttttacc agaataattg gctagttgat ttttttagga cgatttattt ttacctctgt
     1741 tgcatccaca atcaccgtat cctcagcact aagatgagtt tttgaaatcg taacaccact
     1801 ttgaacaaga gttacttcaa cccattggct ccgacggatt aagttgcttt cgtgaatacc
     1861 aagatcagcc gcaatttctt cataagtgcg gtattctcac acatattgaa gagtggccat
     1921 aa
//
LOCUS       DAVLXH010000106         1895 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00028199
            SAMN33607166-rid17955573.denovo.107, whole genome shotgun sequence.
ACCESSION   DAVLXH010000106 DAVLXH010000000
VERSION     DAVLXH010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607166
            Sequence Read Archive: SRR23725544
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1895)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1895)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721421.1
            Genome Coverage       :: 115x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:42:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,210
            CDSs (total)                      :: 2,161
            Genes (coding)                    :: 2,023
            CDSs (with protein)               :: 2,023
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 73 of 138
            Pseudo Genes (incomplete)         :: 60 of 138
            Pseudo Genes (internal stop)      :: 40 of 138
            Pseudo Genes (multiple problems)  :: 31 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1895
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607166-rid17955573.denovo.107"
                     /strain="AUSMDU00028199"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1349"
     gene            147..416
                     /gene="blpJ"
                     /locus_tag="VYO11_002149"
     CDS             147..416
                     /gene="blpJ"
                     /locus_tag="VYO11_002149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpJ"
                     /protein_id="HEV1596616.1"
                     /translation="MNTKMLSQLEVMDTEMLAKVEGGYSSTDCQNALITGVTTGIITG
                     GTGAGLATLGVAGLAGAFVGAHIGAIGGGLTCLGGMVGDKLGLSW"
     gene            485..715
                     /gene="blpU"
                     /locus_tag="VYO11_002150"
     CDS             485..715
                     /gene="blpU"
                     /locus_tag="VYO11_002150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpU"
                     /protein_id="HEV1596617.1"
                     /translation="MDTKMMSQFSVMDTEMLACVEGGGCNWGDFAKAGVGGAAARGLQ
                     LGIKTGTWQGAATGAAGGAILGGVAYAATCWW"
     gene            718..837
                     /locus_tag="VYO11_002151"
     CDS             718..837
                     /locus_tag="VYO11_002151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HEV1596618.1"
                     /translation="MDFKSFIIGLVVGIFGPYMDNLIRKIFSKFPKKDTDSTP"
     gene            1134..1298
                     /locus_tag="VYO11_002152"
     CDS             1134..1298
                     /locus_tag="VYO11_002152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1596619.1"
                     /translation="MKKKILIIFVLYLIMSIFLYPLRESAWYQLFYTIAYVIAVMIYF
                     AINKKKGEKK"
     gene            1295..1699
                     /locus_tag="VYO11_002153"
     CDS             1295..1699
                     /locus_tag="VYO11_002153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000846948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein"
                     /protein_id="HEV1596620.1"
                     /translation="MKTFLAKKRNIFLARLFLGQLPLLVSTYLFLSRQFLNFSVVFQF
                     LLVVINLASILVTVYLTREMRIREFEDDDLVSPRTNQLMFIGLTGFMSIICLYRGITA
                     GESYQQLIAYIGAVLCLIIMLLLMWGLKYYKK"
BASE COUNT          588 a          257 c          391 g          659 t
ORIGIN      
        1 actaaaaaat aggtactgct acctttaaga agatagtaga cgtgtatact tttttaagaa
       61 aatcaaaaag atactataaa aaatctattt gtttattgaa tttaagactt tggtaacaaa
      121 ttgaaaataa aaaggaggta ttcatcatga atacaaaaat gttgtcacag ttagaggtta
      181 tggatactga aatgcttgcg aaagttgaag gggggtatag ctccactgat tgtcaaaatg
      241 cactgattac aggagtcact acgggaatta taactggtgg aactggagca ggtttggcca
      301 ctttaggagt agctggactt gctggtgcat ttgttggagc acacattggt gcaattgggg
      361 gtggattaac atgcttagga ggtatggttg gtgataaatt gggactaagt tggtaagact
      421 tatagtaaaa ttatgaggat tctattctga tttattttag ttttttaaaa aaggagtatt
      481 tgtcatggat acaaaaatga tgtcacaatt ttctgttatg gatactgaaa tgcttgcttg
      541 cgttgaaggt ggcggatgca attggggaga ttttgccaaa gcaggtgttg gaggagcagc
      601 agcaagaggt cttcaactag gcattaaaac aggaacatgg caaggtgcag caactggtgc
      661 tgcgggtgga gctatacttg gaggtgtagc ctatgcagca acatgttggt ggtaattatg
      721 gattttaaaa gttttattat tggtttagta gttggtatat ttggtcctta tatggataat
      781 ttaattagaa aaatattttc aaaatttccc aaaaaggata cagatagtac cccctaaaaa
      841 ataaatttct cccctgtatt tgctagctta atttacaggg gagtttcttt aattttgttt
      901 cgcctgtcaa aatgatatgt gatagcagga tgaaaagtct acaaacaagt tggtatcaat
      961 acaatataaa gaggaaagta tgtttttcat gcttgctttt ttaattttta caattcaaga
     1021 ggttttgatg accatttatg atttgagtga tccaaggtca aaataagtgc tatactagca
     1081 gtgtaaatgt tcttgctcaa ctaagataaa tcgcacattt aggaggaaat cttatgaaga
     1141 aaaaaatact gattattttc gttctgtatc taatcatgtc catctttcta tatccgctta
     1201 gggagagtgc ttggtatcag ctattttata ccatagccta tgtgattgca gttatgatct
     1261 attttgctat caataaaaag aaaggagaaa agaaatgaaa acttttcttg ctaaaaaacg
     1321 gaacatcttc cttgcgagat tgttcttagg tcagttgccc ttgcttgttt ctacttatct
     1381 atttctatct cgtcagtttt taaatttttc cgtagttttc caatttcttt tagtagttat
     1441 taacttggct tctattttgg ttactgttta tctcactagg gaaatgagga taagagagtt
     1501 tgaagatgat gatttggtta gtcctagaac caatcaactt atgtttatcg gcttgacagg
     1561 ttttatgtct attatttgtt tgtatagagg tatcacagca ggagaatctt atcaacaact
     1621 aatcgcttat attggcgctg ttctctgctt aatcatcatg cttctgctca tgtggggctt
     1681 gaagtattat aaaaagtaga gcttaatgaa gtataaaaga aaagggtaag tgtttttgca
     1741 atacttaccc ttttataata gattccctgc gaaacaaaat atggtatagt atattgaaac
     1801 tagaatagta cgcctctact tctaaaacat tgttagaaat cgatttgact gtcctgatcg
     1861 atttatcctg ttcttatttc attttactat agttc
//
LOCUS       DAVLXH010000107         1887 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00028199
            SAMN33607166-rid17955573.denovo.108, whole genome shotgun sequence.
ACCESSION   DAVLXH010000107 DAVLXH010000000
VERSION     DAVLXH010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607166
            Sequence Read Archive: SRR23725544
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1887)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1887)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721421.1
            Genome Coverage       :: 115x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:42:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,210
            CDSs (total)                      :: 2,161
            Genes (coding)                    :: 2,023
            CDSs (with protein)               :: 2,023
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 73 of 138
            Pseudo Genes (incomplete)         :: 60 of 138
            Pseudo Genes (internal stop)      :: 40 of 138
            Pseudo Genes (multiple problems)  :: 31 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1887
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607166-rid17955573.denovo.108"
                     /strain="AUSMDU00028199"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1349"
     gene            complement(<1..1010)
                     /locus_tag="VYO11_002154"
     CDS             complement(<1..1010)
                     /locus_tag="VYO11_002154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HEV1596621.1"
                     /translation="MNIAVIGLGHVGLAYALLFASKYKVVAYDIDSVKINNLKKGTLP
                     SKNEELMKFFCENNLNITFFDTFSEIKNNIDYYIIALPTDYDEKIGSFNTYEIEQTVS
                     KILRVKPNGKIILKSTVPIGFSNKLKRLFDTKNIIFVPEFLREGCSIYDNLYPSRIVV
                     GDETVEGRKIAELFLSISTHSTANIKNVMLVSPTEAEAIKLFSNTFLALRVAFFNELD
                     SFAERRSLNAEVVIKGVCLDPRIGNFYNNPSFGFGGYCLPKDTKQLKKEFIEINAPVI
                     EAIDISNTNRKQFIVKQILERKPKIVGIYKLGMKYNSDNYKESAILSIINELLIVGIK
                     ILV"
     gene            complement(1023..1772)
                     /locus_tag="VYO11_002155"
     CDS             complement(1023..1772)
                     /locus_tag="VYO11_002155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000069862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HEV1596622.1"
                     /translation="MSNNTKYIFLSPHLDDAIFSCSDYISKLTSEGEIVLVITIFSGY
                     PLSQQLQPSAKQFHKLCNLGKYPIEERKKEDRLACERLQCDFRHLSYYECLYRKDRNG
                     NFLYRHIYSELKNEDTLKNDIIKELLMHLDDKCVVYCPLSLGDHVDHVFVNSIGRALE
                     FMRYKVIYYEDFPYVSDSSMVSYMGKTKELKMYQEELDEKHYIDRISSILCYKSQILI
                     IWKSVEKLLNNIKELYLRNGAAYSIRFWIKK"
BASE COUNT          654 a          343 c          213 g          677 t
ORIGIN      
        1 actaaaattt ttataccgac aatcaatagt tcattaatta tacttaaaat agctgactct
       61 ttgtaattat ctgaattata tttcatcccc aatttatata ttcctactat ctttggcttt
      121 cgttccaata tttgtttaac tatgaactgt tttctatttg tgtttgaaat atcaatcgct
      181 tctatcactg gggcatttat ttctataaat tcttttttta attgtttagt atctttggga
      241 agacaatatc ctccaaatcc aaaagaagga ttattataaa aatttccaat tcttggatct
      301 aaacaaacac cttttattac aacttcagca tttaaacttc tcctctcagc aaaagaatct
      361 agttcattaa aaaaagcaac acggagagct aagaatgtgt tagaaaaaag cttaattgct
      421 tctgcttcag taggagaaac taacataaca tttttaatat tggcagtact atgagtacta
      481 atcgaaagga acaactctgc aatttttctt ccttcaactg tctcatctcc aacaactatg
      541 cgacttggat ataaattatc atatatagaa caaccttctc tcaaaaattc agggacaaaa
      601 atgatatttt ttgtatcaaa cagccttttt aatttgtttg aaaagccgat cggaactgtt
      661 gactttaaaa taatctttcc attaggtttt accctcagaa tcttcgatac cgtttgttcg
      721 atttcatatg tattaaaact accaattttc tcatcataat ctgtcggaag cgcaataata
      781 taataatcaa tattattttt aatttcagaa aatgtatcaa aaaaagtaat atttaagtta
      841 ttctcgcaaa aaaacttcat aagctcttca tttttagatg gaagagtgcc cttttttaaa
      901 ttatttattt ttacagaatc tatatcatat gcaacaactt tatatttaga tgcaaatagt
      961 aacgcgtagg ccagcccaac atgccccaaa ccaattactg ctatattcat aaaactactt
     1021 ccttatttct taatccaaaa tctaatagaa taagctgccc cattccttaa atacaactct
     1081 ttaatattgt ttaaaagttt ttcaactgat ttccagatta tcaaaatctg agatttatag
     1141 cacaatattg atgatattct atcaatataa tgtttttcat caagttcctc ttgatacatt
     1201 tttaattctt tagtttttcc catataacta accatactac tatcacttac atatgggaag
     1261 tcctcataat atattacttt ataacgcata aattcaagcg cccttccaat actattcaca
     1321 aaaacatgat caacatggtc accaagtgaa agcggacaat atacgacaca tttatcgtct
     1381 aaatgcatta acagctcttt tatgatatca ttctttaatg tgtcctcatt ttttaattca
     1441 ctatagatat gacggtatag aaaattgcca tttctatctt tcctatagag acattcatag
     1501 tacgataagt gtctaaaatc acattgtaga cgttcacaag ctaacctgtc ttctttcttc
     1561 ctttcttcaa tcggatattt cccaaggtta cacaacttat gaaattgctt agcagagggc
     1621 tgtagctgtt ggctcaaagg gtaaccagaa aatatagtaa taacaagtac aatttctcct
     1681 tctgaagtta attttgaaat ataatcacta caggaaaaaa ttgcgtcatc taaatgtgga
     1741 gataaaaaga tatacttagt attgttactc ataaccattc cctctacaat ttatctaaaa
     1801 actcactaag tgtctgatta aattccacat catcaaaaaa attcacctta ttcttaataa
     1861 tgaatatttc gttaaataaa catatat
//
LOCUS       DAVLXH010000108         1851 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00028199
            SAMN33607166-rid17955573.denovo.109, whole genome shotgun sequence.
ACCESSION   DAVLXH010000108 DAVLXH010000000
VERSION     DAVLXH010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607166
            Sequence Read Archive: SRR23725544
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1851)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1851)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721421.1
            Genome Coverage       :: 115x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:42:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,210
            CDSs (total)                      :: 2,161
            Genes (coding)                    :: 2,023
            CDSs (with protein)               :: 2,023
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 73 of 138
            Pseudo Genes (incomplete)         :: 60 of 138
            Pseudo Genes (internal stop)      :: 40 of 138
            Pseudo Genes (multiple problems)  :: 31 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1851
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607166-rid17955573.denovo.109"
                     /strain="AUSMDU00028199"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1349"
     gene            105..1106
                     /locus_tag="VYO11_002156"
     CDS             105..1106
                     /locus_tag="VYO11_002156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000789954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV1596623.1"
                     /translation="MKNINGKKVTIYDIARLSGFSPKTVSRVINGGVNVKEETYQAIQ
                     KVIEELSYIPNAYAKNLTKKEAINILISVKKIDSFPLIWFHTLLDKVLRTCKEFGVNA
                     IVEYFGEEDTISNSIISSTGSLVDGVIVFYESVDDIRIQYLKKNHMPFLVFGESQTSG
                     VVYVSNNNFQATYDMMKAVTEEKFKNMWLLMGGESHVNKDRERGVRSFLNDKNYFMDL
                     KVIYGLSTIDSVYSYAMQHLTTQNYPDIIFVSGDEKVQGLIRACYEKGILIPDDISII
                     GFDNIPISQYYTPALSTIAPNYVKLAKEMIEGVLAIIKGESVTSVEVSPKFVRRQSF"
     gene            1714..1791
                     /locus_tag="VYO11_002157"
                     /pseudo
     CDS             1714..1791
                     /locus_tag="VYO11_002157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
BASE COUNT          627 a          242 c          367 g          615 t
ORIGIN      
        1 taattttgtg aatttgtgga tcttaaataa tttactaaat tctcttgtta aaaaaaatta
       61 aatattgtat agtaatatta gaatgtttgt aatagaggac tgaaatgaaa aatataaatg
      121 ggaaaaaggt aactatttat gatattgcac gtttatcagg tttttctcca aaaacagttt
      181 cacgagttat taatggtgga gtaaatgtta aagaagaaac ttatcaagcg attcaaaaag
      241 ttatagagga attgtcgtat attccaaatg catatgcaaa aaatttaact aaaaaagaag
      301 ctataaatat attgatttct gtaaaaaaaa tcgactcttt tcctttaatt tggtttcata
      361 cgctgttaga taaagtgtta cggacgtgta aagaatttgg tgttaatgct atagttgagt
      421 actttggaga ggaggataca attagtaatt caattatatc aagcacaggt agcctagtag
      481 atggtgttat tgttttttat gaaagtgtag atgatatcag aattcagtat ttaaagaaga
      541 accatatgcc ttttcttgtt ttcggtgaat ctcaaacgtc tggagtagtc tatgtatcta
      601 ataataattt tcaagctact tatgatatga tgaaagctgt aactgaagaa aaatttaaaa
      661 atatgtggtt gcttatggga ggagaatccc atgttaataa ggatcgtgaa agaggtgtgc
      721 gttcttttct gaatgataaa aattacttta tggatttaaa agtcatttat ggcttatcta
      781 caattgattc agtttattct tatgcaatgc agcacttgac tacccaaaat tatccggaca
      841 ttatttttgt ttcaggagat gaaaaggttc agggcttgat tcgtgcgtgc tatgagaaag
      901 gaattcttat tccagatgat atttctatca ttggatttga taatattcct atttctcagt
      961 attatactcc agctttgtct acaattgctc ccaattatgt taaattggct aaagaaatga
     1021 tagaaggtgt tttagcaatt attaaagggg aaagtgtcac atctgttgaa gtttctccta
     1081 aatttgttag gagacagagt ttctagtatt gtttaattct tgaaaatcct agtggaaaag
     1141 atggagtgtt ctaaaataag ttctgtttag cctccattca gtttctattg agttggatcc
     1201 aatttctaac aagtgggaca tgttcatgtt cgatctaagg aagacatggt cacattcgaa
     1261 tgatattttc aaaaaaatcg taaaaaagtc ttgacaaaga aaaaacaaag tattaaaata
     1321 agttcaacaa atcagaaaag taactatttt tgattttcag ggagcctgtg gggattgtga
     1381 ataggtggtt ggaagtagtg aaagtgggct gattttgaaa atgaatttga aacaatgaaa
     1441 attcggtgcg cacaccttac agtgcagctt gttgttaaac aaggcagaga tgtaaaggga
     1501 tagtcccttt ataattgagg tggcaccgcg ttaccaacgc cctcacacgg aagtatattc
     1561 tgtgtgtggg cttttttcta tccgtcgttt ggtttatctt ttattaggac cttaagtcgc
     1621 tttgatgaac ttgagttcta tctacagctc cttgcctact actaaaagca aacaaaaagg
     1681 ctggactaat acgaaaaaag ctagtaatac tcaatgaaaa tcaaagagca aactaagaaa
     1741 ctagccgcag gttgctcaaa acactgtttt gaggttgtgg atagaactga cgaagtcagc
     1801 tcaaaatact gttttgaggt tgtggataga actgacgaag tcagctcaaa a
//
LOCUS       DAVLXH010000109         1702 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00028199
            SAMN33607166-rid17955573.denovo.110, whole genome shotgun sequence.
ACCESSION   DAVLXH010000109 DAVLXH010000000
VERSION     DAVLXH010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607166
            Sequence Read Archive: SRR23725544
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1702)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1702)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721421.1
            Genome Coverage       :: 115x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:42:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,210
            CDSs (total)                      :: 2,161
            Genes (coding)                    :: 2,023
            CDSs (with protein)               :: 2,023
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 73 of 138
            Pseudo Genes (incomplete)         :: 60 of 138
            Pseudo Genes (internal stop)      :: 40 of 138
            Pseudo Genes (multiple problems)  :: 31 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1702
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607166-rid17955573.denovo.110"
                     /strain="AUSMDU00028199"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1349"
     gene            28..917
                     /locus_tag="VYO11_002158"
                     /pseudo
     CDS             28..917
                     /locus_tag="VYO11_002158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            complement(950..1290)
                     /gene="tnpB"
                     /locus_tag="VYO11_002159"
                     /pseudo
     CDS             complement(950..1290)
                     /gene="tnpB"
                     /locus_tag="VYO11_002159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849103.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
     gene            complement(1506..>1702)
                     /locus_tag="VYO11_002160"
     CDS             complement(1506..>1702)
                     /locus_tag="VYO11_002160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="integrase core domain-containing protein"
                     /protein_id="HEV1596624.1"
                     /translation="DNGMMESFFGILKSEMFYGYEKTFKSLNRLEQAIIDYIDYYNNK
                     RIKVKLKGLSPVQYRTKSFG"
BASE COUNT          533 a          308 c          337 g          524 t
ORIGIN      
        1 ggtgtactgt tatagattca atatactata gactgtaatc aaacaacgat ttggcgaaat
       61 gtaaaaaaat atgaggagtt cggactcgac tctctccttc aagaaacacg tggtggtcgt
      121 aaccatgcat atatgacgat tgagcaagag aaagcctttc ttgcccgtca tttgaagact
      181 acagatgcag gagaatttgt tacaattgat gccttatttc aggcttataa aaaggagtta
      241 ggtcgttcct acacacgtga tgccttctat caactgttga agcgccatgg ttggcgaaat
      301 attatgccac gtccagaaca tcctaggaaa gcagacgctc aaaccattgt cgcgtctaaa
      361 aataaaatct caattcaaga agaaaagaaa gcgatttaaa accagtagac gttttcgtaa
      421 ggttcgcttg atgtaccaag atgaggctgg tttcggtaga atcagtaaac tgggatcttg
      481 ttgggctcca ataggagtag gtccacatgt ccatagtcac tatatacgag aatttcgcta
      541 ttgttatgcc tatacaggcg aatcattttt cttaatagct ggtggatgta atactgagtg
      601 gatgaacgcc tttttagaag agctttcaca agcttatcct tttactcgtt atggacaatg
      661 ctatatggca taaatcaagt accttaaaga ttccgactaa tattggcttt gcatttattc
      721 ctccgtacac accagagatg aaccccattg aacaagtgtg gaaagagatt cgtaaacgtg
      781 gatttaaaaa taaagccttt caaactttgg aagatgtcat gaatcaactt taagatatca
      841 tacaaggact ggagaaggag gtgataaagc ccatcgttaa tcggagatgg actagaatgc
      901 tttttgaaag cagatgagta taaaaagaaa gtcctcattt caatagaaat cacgactttc
      961 tgatggattt atttttggag tgatagaaaa gcccttcata agccagtcta cttgttcagg
     1021 tgtgagagct ttgacatcct tttctgtact gggccaagtc agtctgccgt tctcaaagcg
     1081 tttatatagt agccaaaatc cttgaccatc ccagtaaagg gctttaaagc ggtctttacg
     1141 tccaccacaa aagagaaaga cttgaccgga gaaaggatcc aattcaaagt gggttttaac
     1201 tacataggct aatgagtcta ttccctgcct catatctatc ttgctacaaa caaggtgaac
     1261 ttgacctaaa tcacttagtt gaattatcat agtacaatac ctttcctccg ataattattt
     1321 tttatctagt atactggaag ttggggaatt aggatagata ccttgttatg acgcgcttac
     1381 gtaacttgta actagctgcc tagtttgatc tttgcttctt cattgattag cagtagattt
     1441 caaaatgata aaaacgtata atagtaggtg tagtgtactg ccccccaaaa agttagacaa
     1501 ttaatttatc cgaaggattt agttctgtat tgcacagggc taagtccttt tagttttacc
     1561 ttaattcgtt tattgttgta gtaatcaata tagtctataa tggcttgttc caatcggtta
     1621 agtgatttaa atgttttctc atagccataa aacatttcgg attttaaaat gccaaagaaa
     1681 gattccatca taccgttgtc tt
//
LOCUS       DAVLXH010000110         1614 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00028199
            SAMN33607166-rid17955573.denovo.111, whole genome shotgun sequence.
ACCESSION   DAVLXH010000110 DAVLXH010000000
VERSION     DAVLXH010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607166
            Sequence Read Archive: SRR23725544
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1614)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1614)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721421.1
            Genome Coverage       :: 115x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:42:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,210
            CDSs (total)                      :: 2,161
            Genes (coding)                    :: 2,023
            CDSs (with protein)               :: 2,023
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 73 of 138
            Pseudo Genes (incomplete)         :: 60 of 138
            Pseudo Genes (internal stop)      :: 40 of 138
            Pseudo Genes (multiple problems)  :: 31 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1614
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607166-rid17955573.denovo.111"
                     /strain="AUSMDU00028199"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1349"
     gene            16..906
                     /locus_tag="VYO11_002161"
                     /pseudo
     CDS             16..906
                     /locus_tag="VYO11_002161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000370602.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            903..1373
                     /locus_tag="VYO11_002162"
     CDS             903..1373
                     /locus_tag="VYO11_002162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013851449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1596625.1"
                     /translation="MTRVYKSVRLAYEAKVWIDELIQEKERKIQELNKEDFLDKLEKT
                     LLKNHYDELNGLSFNIILKASIGSVIEESYRNTKHYPIDKWQKLRQQMERDVKNVNPN
                     LETTVTPRIYLDEDVLAGLDDFRYVLMKEDCATRLPRLSYIIKLVVYSYWKEQH"
BASE COUNT          626 a          258 c          247 g          483 t
ORIGIN      
        1 agaataggta gaattatgga taacacaaaa gttattgaat ggttaaatta ctgtgaccaa
       61 aacgatatca aaccatggtt atgggatttt aaaaattgtt actctagcga gttaaccgca
      121 gataatattt caaattttct aaaatataaa aatggagaac tcgtaaatcc ttccacattt
      181 tgtatcacaa aacaggttgg tagtaacgct gactgcgata aagaggcact cccactttat
      241 aatgttttag gttggcaaca ttccgagaga gatataataa gaggtgagac cttaaattct
      301 tatataacta catttactca agctattacc aatgacccga attataaaga aatttgtaaa
      361 aagattggag taaacttaaa tgaatatcta aacaagcagt atccaatctt acaccataat
      421 aaaaactatc aaaatttcaa gatgattcaa aaaaacctaa aagaatttga agcattcgca
      481 aaattaacac atacaatcgg aaactttact gtattgcctc attggatgaa tactggacga
      541 tacaatttct caaaagatta ctgggatatt acaatgcttt ctcttcaaga atggcttact
      601 aatttatctc ctcaagcatg gaaaaatttt attgatacat actatcttca accctatgtt
      661 gataataact atcaaacaga ggtattttgg gaaactcata actacgaata catttatccc
      721 aagaaaaccg aagatttctc catcttccta aaaagagtca atgaacggat tgaggagcgc
      781 gggaaattca tcattaaata aatatgcgat aaactaaata aaaaagattt ccatttctat
      841 aaggaaattg aaaatatgga taaaattaaa tactcaaatg aatttgaaca agagaggaaa
      901 caatgactag agtatataaa agcgtccgcc ttgcgtacga ggcaaaggta tggatagatg
      961 aattgattca agaaaaagaa cgtaaaattc aagaacttaa taaagaggat tttctagata
     1021 aacttgaaaa aacacttctt aaaaatcact atgatgaatt gaatggtctt tcatttaata
     1081 tcattctaaa agcctcaata gggagtgtca tagaagaatc ctatcgaaat actaaacact
     1141 atccaattga caaatggcaa aagctacgtc agcagatgga aagggacgta aaaaatgtta
     1201 atcctaactt agaaaccaca gttactcccc gtatttatct agacgaggat gtgcttgctg
     1261 ggcttgatga ttttcgctat gttttgatga aagaggactg tgctactaga ctacctcgtc
     1321 ttagctacat tatcaaactt gttgtatatt cctactggaa agaacaacac taatctaatc
     1381 agttctactg tttagatttt catttcttta aaatgtatat ttgttgtact actaataaat
     1441 ctagaaaaat aggtaatcta tgtttaaatt aaagaaagtc gctgacttaa aaagaaatta
     1501 tatcatttca actaacaaat taaaggtaac tcattggtca atattaagcc tctctatctg
     1561 cattatgctt actattattg caaatattag agcccctgac cttattaaaa tccc
//
LOCUS       DAVLXH010000111         1457 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00028199
            SAMN33607166-rid17955573.denovo.112, whole genome shotgun sequence.
ACCESSION   DAVLXH010000111 DAVLXH010000000
VERSION     DAVLXH010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607166
            Sequence Read Archive: SRR23725544
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1457)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1457)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721421.1
            Genome Coverage       :: 115x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:42:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,210
            CDSs (total)                      :: 2,161
            Genes (coding)                    :: 2,023
            CDSs (with protein)               :: 2,023
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 73 of 138
            Pseudo Genes (incomplete)         :: 60 of 138
            Pseudo Genes (internal stop)      :: 40 of 138
            Pseudo Genes (multiple problems)  :: 31 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1457
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607166-rid17955573.denovo.112"
                     /strain="AUSMDU00028199"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1349"
     gene            23..358
                     /locus_tag="VYO11_002163"
                     /pseudo
     CDS             23..358
                     /locus_tag="VYO11_002163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(1071..1331)
                     /locus_tag="VYO11_002164"
     CDS             complement(1071..1331)
                     /locus_tag="VYO11_002164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1596626.1"
                     /translation="MRERSATGAQGLSKSIKKHLNDLTRLTASLLGDEKLSAITSSSA
                     VKADMHRFVIELEPVKSTILQNNDISLDQNEIFEILKNFLDG"
BASE COUNT          495 a          276 c          253 g          433 t
ORIGIN      
        1 ttaaaaacag cttatcaaaa aagtcggaca agctggtaaa atcttggctg acagtggtta
       61 tcaagggctc atgaagatat atcctcaagc acaaactcca cgtaaatcca gcaaactcaa
      121 gccgctaaca gttgaagata aagcctgtaa ccatgcgcta tctaaggaga gaagcaaggt
      181 tgagaacatc tttgccaaag taaaaacgtt taaaatgatt tcgacaacct atcgaaatca
      241 tcgtaaacgc ttcggattac gaatgaattt gattgctgat attatcaatc atgaactagg
      301 attttggttt cgcaggaagt ctattatata tatgcacaga catatgaaat ctttttgata
      361 cagccttctt tttacataga gagacagcag ttatgatata tttatccata cacaacatct
      421 tctgtaccaa tactacaata ttggtacatt ttgattacac aatcgtttca aaaaatatga
      481 tggaagccta agtattttat agtaattccc ttcctatcaa ctagatcaac cagttgagtg
      541 ttgaatgttg aaacacccta gcctcagcaa aggactatga tcagcatttc ctagccaata
      601 ggacgctcca aatcacctat tctaagtcca tcactagctt ggtcagtaag atacagactg
      661 caaggcgaga ctgacgtggt tgatgagatt ttggaagagt attacaatca tagattcacc
      721 agtagacttg accgcagatt taactatagt agattgaaac tagaatagta catctctgct
      781 tctaaaacat tgttagaaat cgatttgact gtcctgatca atttgtcctg ttctcgtttc
      841 atttcactat actaaaaaac cacctgaaac aaatcaagtg actagaggat aaaaacaaag
      901 actaggcaaa aagttttgaa aagcaaaaaa cgcataatat caggtcttga aaaaccttga
      961 tactatacgt ttgattgtgg gaagattgac ttcattttct cctgaaattg aagttttttc
     1021 tagtttccag atatagacga attcaatata gccatctcgc tacaattatt ttaaccatcg
     1081 agaaaatttt tcagaatttc aaaaatttca ttttgatcca atgaaatgtc attattttga
     1141 agaatagttg acttcacagg ctctaattct atcacaaagc ggtgcatgtc tgcttttacc
     1201 gcactacttg atgttatagc cgataacttt tcatctccta gcaaggaagc tgtcaaacgg
     1261 gtaaggtcat tcaaatgctt tttaatggac ttacttaaac cttgagcacc tgtggcagag
     1321 cgctccctca tatccagcca agctttagcc ttaaaaataa ttaatactca atgaaaatca
     1381 aagagcaaac taggaagcta gctgcaggct gctcaaaaca ctgttttgag gttgtagatg
     1441 gaagctgacg tggtttg
//
LOCUS       DAVLXH010000112         1457 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00028199
            SAMN33607166-rid17955573.denovo.113, whole genome shotgun sequence.
ACCESSION   DAVLXH010000112 DAVLXH010000000
VERSION     DAVLXH010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607166
            Sequence Read Archive: SRR23725544
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1457)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1457)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721421.1
            Genome Coverage       :: 115x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:42:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,210
            CDSs (total)                      :: 2,161
            Genes (coding)                    :: 2,023
            CDSs (with protein)               :: 2,023
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 73 of 138
            Pseudo Genes (incomplete)         :: 60 of 138
            Pseudo Genes (internal stop)      :: 40 of 138
            Pseudo Genes (multiple problems)  :: 31 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1457
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607166-rid17955573.denovo.113"
                     /strain="AUSMDU00028199"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1349"
     gene            129..1307
                     /locus_tag="VYO11_002165"
     CDS             129..1307
                     /locus_tag="VYO11_002165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HEV1596627.1"
                     /translation="MTLSKKQLQLRAKILETVYTLGPISRIEIATKTGITPATTSSIT
                     NDLIKENILLELGEDEHDTSVGRKKILLDIQAKRFYYIGCELSEKHFTFALGDNLGNI
                     LKEEKEIVTKQLIQEKGNQLINQTLKQFLNNCSDYEIEAIGIALPGRYLDDYKITTNN
                     PLWQHIDLEMIQSHFDKPLFFSNNVNCMAIGKRLFSRQQNDPNFAYFHFARGMHCSYI
                     YDGNIYGKGNLMIGEIGHTVVSSEGEECSCGRKGCLQTFAGESWLIKKSKILYHQSPY
                     SLLPSLVKNADDIDIQVILTAYQLGDTGIITLIHQALLYLSQTILNISMMIDSQKIYL
                     HSPLLTNQHIIQKLYSEMNYKPKLLYNRLPEVIIEPYNDFTAAHSAIALCLYHTILHS
                     "
BASE COUNT          539 a          263 c          210 g          445 t
ORIGIN      
        1 tttattatca atatataata aaaagagacc agtaagcaat gaaaagctta aaaagattaa
       61 catctacatt tatccatagt aaaaaatcat aggattttaa gaatctgaca actaggaaga
      121 aaactaatat gaccttatct aagaaacaat tacaactacg agctaaaata ctggaaacag
      181 tttacacatt aggtcccatt tcacgaattg aaatcgctac taaaacagga ataacacctg
      241 caacaactag cagtatcaca aatgatctga ttaaagaaaa cattctctta gaacttggtg
      301 aagacgaaca cgatacaagc gtagggagaa aaaaaatcct gctagacatt caagctaaac
      361 gattttacta cattggttgt gaactatctg aaaaacattt cacttttgct ttaggagata
      421 atctaggaaa tatcttaaag gaagagaaag aaattgttac taaacagtta atccaagaaa
      481 agggaaatca actcattaac cagacactaa agcaattctt aaataactgc tctgattatg
      541 aaatagaagc aattggaatc gcgctacctg gtcgctattt agatgattat aaaataacaa
      601 caaacaatcc tttatggcaa catatcgact tagaaatgat tcaatcccac tttgataagc
      661 ctttgttttt ctctaacaat gttaactgta tggctatagg taaacgccta tttagtcgcc
      721 aacagaatga ccctaatttt gcttattttc attttgctag aggtatgcac tgttcttata
      781 tctacgacgg aaacatttat gggaaaggaa atctaatgat tggagaaata gggcatacag
      841 ttgtttcatc tgagggagaa gaatgtagct gcgggcgcaa gggatgctta caaacttttg
      901 ctggagaatc ttggttaatc aaaaaatcaa aaattctata tcatcaatct ccctattctc
      961 tacttcctag tttagtcaaa aatgccgatg atattgatat ccaagttatt ttaaccgctt
     1021 atcaattagg tgacactgga ataatcacac ttatccatca agccttactc tatcttagtc
     1081 aaaccatttt aaatatcagt atgatgattg actctcaaaa aatctaccta catagtcctt
     1141 tactaacaaa tcaacacatc atccaaaaac tatatagtga aatgaactac aaacccaaac
     1201 tgctctataa tcgcctacct gaagtcatta ttgaacctta caatgatttt acagccgcac
     1261 actcagctat tgcactttgt ttgtatcata caattctaca ttcttaattt tctattacat
     1321 ttaataaata ggctaaaaag agggagtata tcataaaaag cgaataaacc tgttttctga
     1381 aaatcagaat tctgttttgt tcgctttctt tatatttgga attatactcc tatctcccct
     1441 ttttcataat gtatagt
//
LOCUS       DAVLXH010000113         1409 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00028199
            SAMN33607166-rid17955573.denovo.114, whole genome shotgun sequence.
ACCESSION   DAVLXH010000113 DAVLXH010000000
VERSION     DAVLXH010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607166
            Sequence Read Archive: SRR23725544
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1409)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1409)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721421.1
            Genome Coverage       :: 115x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:42:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,210
            CDSs (total)                      :: 2,161
            Genes (coding)                    :: 2,023
            CDSs (with protein)               :: 2,023
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 73 of 138
            Pseudo Genes (incomplete)         :: 60 of 138
            Pseudo Genes (internal stop)      :: 40 of 138
            Pseudo Genes (multiple problems)  :: 31 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1409
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607166-rid17955573.denovo.114"
                     /strain="AUSMDU00028199"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1349"
     gene            19..1365
                     /gene="gdhA"
                     /locus_tag="VYO11_002166"
     CDS             19..1365
                     /gene="gdhA"
                     /locus_tag="VYO11_002166"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HEV1596628.1"
                     /translation="MTSAKEYIQSVFETVKTRNGHEAEFLQAVEEFFNTLEPVFEKHP
                     EYIEENILARITEPERVVSFRVPWVDRDGKIQVNRGYRVQFNSAVGPYKGGLRFHPTV
                     NQGILKFLGFEQIFKNVLTGLPIGGGKGGSDFDPKGKTDAEVMRFCQSFMTELQKHIG
                     PSLDVPAGDIGVGGREIGYLYGQYKRLNQFDAGVLTGKPLGFGGSLIRPEATGYGLVY
                     YTEEMLKANGNSFAGKKVVISGSGNVAQYALQKATELGATVISVSDSNGYVIDENGID
                     FDLLVDVKEKRRARLTEYAAEKATATYHEGTVWTYAGNYDIALPCATQNEINGEAAKR
                     LVAQGVICVSEGANMPSDLDAIKVYKENGILYGPAKAANAGGVAVSALEMSQNSLRLS
                     WTREEVDDRLKDIMTNIFNTAKTTSETYGLDKDYLAGANIAAFENVANAMIAQGIV"
BASE COUNT          418 a          285 c          306 g          400 t
ORIGIN      
        1 caataaaagg agaacgatat gacatctgct aaagaatata tccaaagcgt gttcgaaact
       61 gtaaaaactc gtaacgggca cgaggctgaa ttcctccaag ctgttgaaga atttttcaac
      121 actttggaac ctgtatttga aaaacaccct gagtatatcg aagaaaatat cttggcacgt
      181 attactgagc ctgagcgcgt ggtttctttc cgtgttcctt gggttgaccg tgatggaaaa
      241 attcaagtaa accgtggtta ccgtgttcaa ttcaactcag ctgttggacc atacaaaggt
      301 ggacttcgtt tccacccaac tgtaaaccaa gggatcttga aattcctcgg atttgaacaa
      361 atctttaaaa atgtcttaac tggacttcct atcggtggag gtaaaggtgg atcagacttc
      421 gatcctaaag gtaaaacaga tgctgaagtg atgcgcttct gccaaagctt catgactgaa
      481 ttgcaaaaac acatcggacc atcacttgac gtacctgctg gtgatatcgg tgttggtgga
      541 cgtgagattg gttaccttta cggtcaatac aaacgtctta accaatttga tgctggtgtc
      601 ttgactggta aacctcttgg atttggtggt agcttgattc gtccagaagc aactggttac
      661 ggtttggttt actatactga agaaatgctc aaagctaacg gtaacagctt tgctggtaag
      721 aaagtcgtta tttcaggttc tggtaacgtt gctcaatatg ctcttcaaaa agcaactgaa
      781 ctcggtgcaa ctgttatttc tgtttctgac tcaaatggtt atgtcatcga tgaaaatggt
      841 atcgacttcg atcttttggt tgatgttaaa gaaaaacgtc gtgctcgttt gactgagtat
      901 gcagctgaaa aagcaactgc aacctaccac gaaggtactg tatggactta cgctggaaac
      961 tatgacattg ctcttccatg tgccactcaa aacgaaatca acggtgaagc agctaaacgt
     1021 ttggttgctc aaggcgttat ctgtgtatct gaaggtgcca acatgccgag cgaccttgat
     1081 gccatcaaag tttacaaaga aaatggtatc ttatacggac ctgcaaaagc tgccaacgct
     1141 ggtggtgtag ccgtttcagc tcttgaaatg agccaaaaca gtcttcgcct ctcatggact
     1201 cgtgaagaag ttgatgaccg tctcaaagac atcatgacaa acatcttcaa cacagctaaa
     1261 acaacttcag aaacatacgg tcttgataaa gactaccttg caggagctaa cattgctgcc
     1321 tttgaaaatg tagcaaatgc catgattgca caaggtattg tttaagattt atttactcaa
     1381 tcctcaatca ctacgattgg ggattttta
//
LOCUS       DAVLXH010000114         1387 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00028199
            SAMN33607166-rid17955573.denovo.115, whole genome shotgun sequence.
ACCESSION   DAVLXH010000114 DAVLXH010000000
VERSION     DAVLXH010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607166
            Sequence Read Archive: SRR23725544
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1387)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1387)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721421.1
            Genome Coverage       :: 115x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:42:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,210
            CDSs (total)                      :: 2,161
            Genes (coding)                    :: 2,023
            CDSs (with protein)               :: 2,023
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 73 of 138
            Pseudo Genes (incomplete)         :: 60 of 138
            Pseudo Genes (internal stop)      :: 40 of 138
            Pseudo Genes (multiple problems)  :: 31 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1387
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607166-rid17955573.denovo.115"
                     /strain="AUSMDU00028199"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1349"
     gene            88..1266
                     /locus_tag="VYO11_002167"
     CDS             88..1266
                     /locus_tag="VYO11_002167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1596629.1"
                     /translation="MTLPVRKSLHDAVLQASKADTWEQATKEWNEVSLIFNGIGRSNC
                     VCGNAIKYAYELFNGVTGQRLFPIGSDCVRHFHRLSLDQQLEEEEKLLRKVENLTRKA
                     QKKEKIKVNKSDFDERLLKWLWEKGVFKPNRGNQFAPERDCQLFLEVFQGGSWTKAEP
                     KKKARMEEVLEKCIKPFLLGKSDDQLYLVKLGKEKIDYEQELRIQAEKERKKRDKIAK
                     QYADNLVLAMGPAERAYQDYFGFTETLTQEERKWEKILFGKNRAERAIKAKQYQKELE
                     KDQRIASQDPIERKQKQTWLLNSYFRELPEEKARFSRLLLEYRKNGEVPFSTEYLSDH
                     LIDFFYKMKAFEFEIAPEQVRDFLKKSLQEDHRSSAQGSWIEGILLNCLKPFLERLVI
                     "
BASE COUNT          475 a          270 c          292 g          350 t
ORIGIN      
        1 acaacctcaa aacagtgttt tgagctgact gcgactagct ttctagtttg ctctttgatt
       61 tttattgagt attagaaagg agacctcatg acacttccag ttagaaaatc cctgcacgat
      121 gcagttttac aggcttcgaa agcggatact tgggaacaag ctaccaagga atggaatgaa
      181 gtttccttga tttttaacgg tatcggccgt agcaattgtg tctgtggaaa tgccatcaaa
      241 tacgcttatg aactctttaa cggtgtcaca ggccaacgcc tctttccaat tggtagcgac
      301 tgtgttcgtc attttcatcg attgtccctt gaccagcaat tggaagagga agaaaaactg
      361 ctcagaaagg ttgaaaatct aaccagaaaa gctcagaaaa aggaaaaaat caaggtcaat
      421 aaaagtgact ttgacgagcg acttctaaaa tggctctggg aaaaaggtgt tttcaaaccc
      481 aatcgtggca atcaatttgc gcctgagaga gactgccagc ttttcctaga agtctttcag
      541 ggaggaagtt ggaccaaggc ggaaccaaag aaaaaggctc ggatggaaga agtccttgaa
      601 aagtgtatca aacccttttt acttgggaaa tcggatgacc aactctacct tgtcaagcta
      661 ggcaaggaga aaattgacta cgaacaagaa ctccgtatcc aggcagagaa agaacgcaag
      721 aagagggata aaatcgccaa gcaatatgca gacaatctgg ttctagccat gggacccgca
      781 gagcgtgctt atcaagatta ctttggcttt acagagaccc tgactcaaga agaacgcaag
      841 tgggaaaaaa ttctttttgg taaaaataga gcagaacggg ctatcaaggc caaacaatac
      901 caaaaagagc tggaaaaaga ccaacgaatt gccagtcagg atccaattga aagaaaacag
      961 aagcagactt ggctcctcaa ttcctatttt cgtgagcttc ctgaagaaaa agctcgattt
     1021 tctaggctct tattagaata tcgaaaaaat ggtgaagtac ccttttcaac tgaatacctg
     1081 tcagatcatc tcatcgactt tttctataaa atgaaagcct ttgaatttga aatcgcacca
     1141 gaacaagtcc gagattttct aaaaaaaagc ctgcaggaag accatcgctc atcagcacaa
     1201 ggaagctgga tagaaggaat tctcctcaac tgcctcaaac catttttaga acgattagtg
     1261 atatgagtaa cacctaccgt gtaaatttca tggtaggtgt tattgtacct caaaataata
     1321 taaaacaaag tatgaaagcg catctcaatt ttaagacttt tttgtaaatt aagagtataa
     1381 ttaaggt
//
LOCUS       DAVLXH010000115         1346 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00028199
            SAMN33607166-rid17955573.denovo.116, whole genome shotgun sequence.
ACCESSION   DAVLXH010000115 DAVLXH010000000
VERSION     DAVLXH010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607166
            Sequence Read Archive: SRR23725544
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1346)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1346)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721421.1
            Genome Coverage       :: 115x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:42:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,210
            CDSs (total)                      :: 2,161
            Genes (coding)                    :: 2,023
            CDSs (with protein)               :: 2,023
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 73 of 138
            Pseudo Genes (incomplete)         :: 60 of 138
            Pseudo Genes (internal stop)      :: 40 of 138
            Pseudo Genes (multiple problems)  :: 31 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1346
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607166-rid17955573.denovo.116"
                     /strain="AUSMDU00028199"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1349"
     gene            complement(176..1346)
                     /locus_tag="VYO11_002168"
                     /pseudo
     CDS             complement(176..1346)
                     /locus_tag="VYO11_002168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT          369 a          261 c          230 g          486 t
ORIGIN      
        1 gaagaattta ttcgagaaac agaacactcc ttaaatatta gagaaaaaac actgtataac
       61 attgtgaata tagtaagtga catccataaa ctgggaatat aaaattgtag atatagctcc
      121 tacaaatttt atatatacca aaaatgtact gcaccccaaa agttagacaa ttaatttatc
      181 cgaaggattt agttctgtac tgcacagggc taagtccttt tagttttacc ttaattcgtt
      241 tattgttgta gtaatcaata tagtctacaa tagcttgttc caattgctta agcgactgaa
      301 acgacttctc ataaccgtaa aacatttccg atttcagaat cccaaagaag gactccatca
      361 taccattgtc tgggctgtta cccttacgtg acatggatgc ttgaattccc ttactctcta
      421 gaaaccgatg ataagaatcg tgttgatatt gccagccttg gtcactatgg agaatcgtat
      481 tctcatagtg cttctctgtg aatgcctgtt ccaacattgt ttgtacttgt tctaagttgg
      541 gtgaagttga aagattatag gcgataattt cgctattaaa gccatctaaa actggtgata
      601 agtaaagctt ttgagtactt gctggaatgg caaattctgt cacatctgtg tagcactttt
      661 ccattgtttt agagccttca aattggcctt gaatgagatt ctctgccttc ttaccaacgt
      721 ctcctttatg agaagaatat tttcgtttct gtcgcatttt agcttgtaaa ttgagtactt
      781 tcatcaagcc ttgaactctt ttatgattta ccagataacc acgatttctt agttctaaat
      841 gaacccggcg ataagtataa tttcccttgt gttcgataaa aatggattga atttcagctt
      901 taagctcttg gtccttatct ggtttatcta gctgtttcaa gtgatagtag taggtcgaac
      961 gagctagttt aatggctttt agaagaagag ctaacgaaaa ctcagtcatt aattcttgaa
     1021 caatttctgt ctttcttctt tctctttttc ctccttcaat cggagttctc ttaacttttt
     1081 taggatggca ttctccgctc tcaggtactc attttctgct tgaagatgtt ctaattctgt
     1141 cctctcttca ggtctcgttt ttggcttacg tcccatttta ggtactctcc ctcttgtttt
     1201 ctcaacaata gtatacccgt ttttcctgta ttgtgctagc cagttaagaa gtatcgtacg
     1261 acttgggagg ccgtattcaa gagaaactct atctttagtc cagccttcat gtcagacttt
     1321 attaatcatt tcttgtttta aatcag
//
LOCUS       DAVLXH010000116         1278 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00028199
            SAMN33607166-rid17955573.denovo.117, whole genome shotgun sequence.
ACCESSION   DAVLXH010000116 DAVLXH010000000
VERSION     DAVLXH010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607166
            Sequence Read Archive: SRR23725544
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1278)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1278)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721421.1
            Genome Coverage       :: 115x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:42:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,210
            CDSs (total)                      :: 2,161
            Genes (coding)                    :: 2,023
            CDSs (with protein)               :: 2,023
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 73 of 138
            Pseudo Genes (incomplete)         :: 60 of 138
            Pseudo Genes (internal stop)      :: 40 of 138
            Pseudo Genes (multiple problems)  :: 31 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1278
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607166-rid17955573.denovo.117"
                     /strain="AUSMDU00028199"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1349"
     gene            complement(1..413)
                     /locus_tag="VYO11_002169"
                     /pseudo
     CDS             complement(1..413)
                     /locus_tag="VYO11_002169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
     gene            complement(659..970)
                     /locus_tag="VYO11_002170"
     CDS             complement(659..970)
                     /locus_tag="VYO11_002170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1596630.1"
                     /translation="MIEAQGFLVDKQTRCIHYHSKLDIIALQCYDCKKYYACYRCHDS
                     LENHPFEPYPLSLIQDKPILCGVCLKLLTYKQYKESLSCPFCFSRFNPGCQNHKERYF
                     K"
     gene            complement(985..>1278)
                     /locus_tag="VYO11_002171"
     CDS             complement(985..>1278)
                     /locus_tag="VYO11_002171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase C-terminal
                     domain-containing protein"
                     /protein_id="HEV1596631.1"
                     /translation="EVVSYDDAAQTATIRQRNVINEGDQVEFYGPGFRHFETYIEDLH
                     DAKGNKIDRAPNPMELLTIKVPQPVQSGDMVRALKEGLINLYKEDGTSVTVRA"
BASE COUNT          383 a          264 c          219 g          412 t
ORIGIN      
        1 attttacgac gagcaccaaa caactgctca ttttcagatg gtgtaccata gtaaaatcct
       61 gtagccagtt cacgttgggc aaccttccac atctcgtcca ccaagtcttg tttgatagct
      121 tcaaactttt caggactttc aagataggca tccacagccg ccttgtagca gttggttact
      181 gttaatacat agtgaataga ctccatacgt ccttcgattt ttagactgtc cacaccattt
      241 tcaatcatat ctggaatgtg gtcaatcata gacatgtcaa cggctgacat tgaaaattct
      301 tctggaatct caccctgcaa actcttacgt tctttcccaa atggcatatc gtaaaggtcg
      361 tacttccaac ggcatgactg agaacatcca ccacggttgg catcacgcat actctagacg
      421 gattgttttg acaattctaa tcttttagac tttgcataat aactgttaaa cagttgaaaa
      481 ttgacccagt tttaacaagt agtcaaaata ccagataaag gaaaaaagtc tttaaaatct
      541 taaaaacgca tagtatcagg tattgaacaa tcttgatatt atgcgtttta ttgtgggaag
      601 atttacttca ttttctcttg gaattgagtt ttctcctact tcaaaactag atgatttgct
      661 atttaaaata gcgttcctta tgattttggc aacctggatt aaagcgagaa aaacaaaagg
      721 ggcaacttaa gctttcttta tattgcttat atgttagtag ttttagacaa acaccacata
      781 aaataggctt atcctgtatc aaagataagg gatacggctc aaaagggtga ttttctaatg
      841 aatcatgaca ccgataacaa gcataatact ttttacaatc atagcattgt aaagcaataa
      901 tatccagctt gctatggtaa tgaatgcatc ttgtttgctt atccactaag aaaccctgtg
      961 cctctatcat ttccttttcc tttcttaagc tcgaactgtg acgctggttc catcttcctt
     1021 ataaagattg atgagtcctt cttttaatgc acgaaccatg tctcctgatt gaacgggttg
     1081 aggcacctta atagtcaata gttccattgg atttggagcg cggtcgattt tattgccttt
     1141 ggcatcatgc aaatcttcaa tataggtttc aaaatgacgg aaacctggac cataaaactc
     1201 aacttggtcc ccttcgttaa tgacatttcg ttgacgaata gttgctgttt gtgccgcatc
     1261 atcataagaa accacttc
//
LOCUS       DAVLXH010000117         1237 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00028199
            SAMN33607166-rid17955573.denovo.118, whole genome shotgun sequence.
ACCESSION   DAVLXH010000117 DAVLXH010000000
VERSION     DAVLXH010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607166
            Sequence Read Archive: SRR23725544
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1237)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1237)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721421.1
            Genome Coverage       :: 115x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:42:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,210
            CDSs (total)                      :: 2,161
            Genes (coding)                    :: 2,023
            CDSs (with protein)               :: 2,023
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 73 of 138
            Pseudo Genes (incomplete)         :: 60 of 138
            Pseudo Genes (internal stop)      :: 40 of 138
            Pseudo Genes (multiple problems)  :: 31 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1237
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607166-rid17955573.denovo.118"
                     /strain="AUSMDU00028199"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1349"
     gene            60..410
                     /locus_tag="VYO11_002172"
     CDS             60..410
                     /locus_tag="VYO11_002172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
                     /protein_id="HEV1596632.1"
                     /translation="MLRHPCISPTNDLIAKKIFSNPEITCQFIRDMLDLPAKNVTILE
                     GSDIHVLLSMPYSVQDFYTSIDVLAELDNGPQVIIEIQVHHQNFFINHLWTYLCSQVN
                     QNLEKIRQREGDTH"
     gene            625..741
                     /locus_tag="VYO11_002173"
     CDS             625..741
                     /locus_tag="VYO11_002173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000233180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
                     /protein_id="HEV1596633.1"
                     /translation="MVGVFRQQALYPATATSHYPSKSTAGLQELVRGGQENV"
     gene            734..967
                     /locus_tag="VYO11_002174"
     CDS             734..967
                     /locus_tag="VYO11_002174"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1596634.1"
                     /translation="MFSQLHMREEQVLLAQDYALETARAEGLEQGLERGKVEGREERK
                     LFAFLDIVRQGLLTSEVASQQLGMSVSEFEALL"
     gene            1094..>1237
                     /locus_tag="VYO11_002175"
     CDS             1094..>1237
                     /locus_tag="VYO11_002175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV1596635.1"
                     /translation="MEQLHFITKLLDIKDPNVQILNIINKDTHKEIIAKLDYDAPSCP
                     ECGN"
BASE COUNT          405 a          247 c          259 g          326 t
ORIGIN      
        1 ttttctgata gagttgttca catcttattt caactcacta tagaaggagg aaaaggagga
       61 ttctcagaca tccgtgcatc agcccaacta atgatttgat tgctaagaaa atattcagca
      121 atccagaaat cacttgtcaa tttattcgcg atatgctgga cttgccagca aaaaatgtga
      181 ccattttgga gggaagcgat attcacgtat tactctccat gccttactcg gtgcaggatt
      241 tttataccag tatagacgtc ttggcggagt tggataacgg tccacaagta attattgaga
      301 ttcaagtcca tcatcagaat tttttcatca atcacttgtg gacttacctg tgcagtcagg
      361 ttaatcaaaa tcttgaaaaa attcgtcagc gagaaggtga tactcactag agctacaaac
      421 acatcgctcc tgtttacgcc attgctatcg tggatagtaa ttatttctca gatgacctgg
      481 cttttcatag ctttagtatg cgcgaagaca caacaggtga ggtattggcg attaccaaca
      541 atggacagga aaaccatctg gttaagatgg cattcttgga attaaaaaat acagagaaac
      601 cagcaaagac aaggttcgca agccatggtt ggagtttttc ggcaacaagc cctttaccca
      661 gcaaccgcaa cgagccatta cccaagcaaa tcaactgctg gactacaaga gctggtccga
      721 ggaggacagg aaaatgttta gtcaactaca tatgcgagaa gaacaagtct tgttagcaca
      781 ggactatgcc ttggaaactg ctagggctga aggccttgaa caaggactag agcgtgggaa
      841 agttgaagga agggaagaaa ggaaactttt tgccttccta gacatagtac gccaaggtct
      901 tctgacttct gaggttgcca gccagcaatt aggtatgtca gtatctgaat ttgaggcact
      961 gttgtaaaat ggctctataa tatttgtagt gtgtaaatcc cctatggata ttatggagcc
     1021 tattttgtgt agaaaaaaag tcccatatga cctataatga aaagcgacaa aacaactcat
     1081 tagaaagaat catatggaac aattacattt tatcacaaaa ttactagaca ttaaagaccc
     1141 taatgtccag attttaaaca tcatcaataa ggatacacac aaggaaatca tcgccaaact
     1201 ggactacgac gccccatctt gccctgagtg cggaaac
//
LOCUS       DAVLXH010000118         1207 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00028199
            SAMN33607166-rid17955573.denovo.119, whole genome shotgun sequence.
ACCESSION   DAVLXH010000118 DAVLXH010000000
VERSION     DAVLXH010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607166
            Sequence Read Archive: SRR23725544
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1207)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1207)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721421.1
            Genome Coverage       :: 115x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:42:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,210
            CDSs (total)                      :: 2,161
            Genes (coding)                    :: 2,023
            CDSs (with protein)               :: 2,023
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 73 of 138
            Pseudo Genes (incomplete)         :: 60 of 138
            Pseudo Genes (internal stop)      :: 40 of 138
            Pseudo Genes (multiple problems)  :: 31 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1207
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607166-rid17955573.denovo.119"
                     /strain="AUSMDU00028199"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1349"
     gene            complement(<1..971)
                     /locus_tag="VYO11_002176"
     CDS             complement(<1..971)
                     /locus_tag="VYO11_002176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEV1596636.1"
                     /translation="MTKTLKRPEVLSPAGTLEKLKVAVQYGADAVFIGGQAYGLRSRA
                     GNFTFEQMEEGVQFAAKYGAKVYVAANMVMHEGNEAGAGEWFRKLRDIGIAAVIVSDP
                     ALIMIAATEAPGLEIHLSTQASATNYETLEFWKELGLTRVVLAREVSMEELAEIRKRT
                     DVEIEAFVHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYDLYDMPFGKERKSL
                     QGEIPEEFSMSAVDMSMIDHIPDMIENGVDSLKIEGRMKSIHYVSTVTNCYKAAVDAY
                     LESSEKFEAIKQDLVDEMWKVAQRELATGFYYGIPSENEQLFGARRK"
BASE COUNT          359 a          288 c          212 g          348 t
ORIGIN      
        1 attttacggc gagcaccaaa caactgctca ttttcagatg gtataccgta gtagaaacct
       61 gttgccaatt cacgttgggc aaccttccac atctcgtcca ctaagtcttg tttgatagct
      121 tcaaactttt cagaactttc aagataggca tccacagccg ccttgtagca gttggttact
      181 gttgatacgt agtgaataga cttcatacgt ccttcgattt ttagactgtc cacaccattt
      241 tcaatcatat ctggaatgtg gtcaatcata gacatgtcaa cggctgacat tgaaaattct
      301 tctggaatct caccctgcaa actcttacgt tctttcccaa atggcatatc gtaaaggtcg
      361 tatttccaac ggcatgactg agaacatcca ccacggttgg catcacgcat actcatgtgg
      421 tttgaaagag tacaacgtcc agagtatgaa atacacatag ctccatggac aaaggcttca
      481 atttcaacat ctgtacgttt gcggatctca gctaattctt ccattgaaac ctcacgcgct
      541 aaaacgacac gagtcaagcc tagctctttc cagaactcaa gggtttcata gttagtggca
      601 ctggcttggg tagaaaggtg gatttcaagg cctggtgctt cagtcgctgc aatcataatc
      661 aaggctgggt cagatacgat aactgctgca atcccgatat cacgcagttt acggaaccac
      721 tcaccagcac cagcttcatt tccttcgtgc ataaccatat tagccgctac atagaccttg
      781 gcaccatact tggccgcaaa ctgcacgcct tcttccatct gttcgaaagt aaagtttccc
      841 gcacggctac gaagaccata ggcctgacca ccgataaaga cagcatctgc tccatactga
      901 acagctacct ttagcttctc taaagtccct gcaggtgata aaacctcagg acgttttaat
      961 gtttttgtca taatttctcc tatttgcaat ataaaagttt gacatttttc cttctcattt
     1021 tatagtaaat aaaggataaa atcaagccta gacggattgt tttgacaatt ctaatctttt
     1081 agactttgca taataactat taaacagtcg aaaattaccc cagttttaac aagtagtcaa
     1141 aaagtctaaa aaagtaaaaa ccagtatccc aagatactga ctcgtaaaaa tatataaatt
     1201 agtcctt
//
LOCUS       DAVLXH010000119         1153 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00028199
            SAMN33607166-rid17955573.denovo.120, whole genome shotgun sequence.
ACCESSION   DAVLXH010000119 DAVLXH010000000
VERSION     DAVLXH010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607166
            Sequence Read Archive: SRR23725544
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1153)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1153)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721421.1
            Genome Coverage       :: 115x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:42:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,210
            CDSs (total)                      :: 2,161
            Genes (coding)                    :: 2,023
            CDSs (with protein)               :: 2,023
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 73 of 138
            Pseudo Genes (incomplete)         :: 60 of 138
            Pseudo Genes (internal stop)      :: 40 of 138
            Pseudo Genes (multiple problems)  :: 31 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1153
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607166-rid17955573.denovo.120"
                     /strain="AUSMDU00028199"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1349"
     gene            1..449
                     /locus_tag="VYO11_002177"
                     /pseudo
     CDS             1..449
                     /locus_tag="VYO11_002177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="winged helix-turn-helix domain-containing
                     protein"
     gene            452..1123
                     /locus_tag="VYO11_002178"
                     /pseudo
     CDS             452..1123
                     /locus_tag="VYO11_002178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259617.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Dyp-type peroxidase"
BASE COUNT          343 a          207 c          256 g          347 t
ORIGIN      
        1 tctgatgggc aaatcttata aagagattat agaactttta gactgtaatc aaacaacgat
       61 ttagcgaaat gtaaaaaaat atgaggagtt cgaactcgac tctctccttc aagaaacacg
      121 tagtggtcgt aaccatgcat atatgacagt tgaggaagag aaagcctttc ttgcccgtca
      181 tttgaaggct gcagagtcag gagaatttgt tacaattgat gccttatttc aggcttataa
      241 aaaggagtta ggtcgttcct acacacgtga cgccttctat caactgttga agcgccatgg
      301 ttggcgaaat attatgccac gtccagaaca tcctaagaaa gcagacgctc aaaccattgt
      361 cgcgtctaaa aataaaatct caattcaaga agacaagaaa gcgctttaaa atcagtagac
      421 cttttcataa ggttcgcttg atgtaccaaa tagtacgccc atgcaaaaga atatctattt
      481 tgttgtcttg gacctgcata cgacggatag agataaaatt atccagctat tcaaggattg
      541 gacggatgac agttgggctc aatcctcatc gtttgacgct gacttttggt gtatctgcaa
      601 gtttcttgaa aaggatgaac ttggaaaaca agcgccctcg actgttcagg gatttacctc
      661 tatttcctaa ggagcaatta cgtgaaaaat atactggtgg agatattgtg attcatgctt
      721 gtgcagatga tgagcaaatt gcctttcacg ctattcgcaa tctcatccgt aaggggagaa
      781 atgcggtgcc ccctttggta agaaaaatga gtttgatgaa gtggatttga gtctcttacc
      841 tgatgattcg catgtttgtt tggccaaaga agtggataag ccacttttac gtcgttctta
      901 ttcttactca gatggcattg atgaaaagac tggtcagttt gatacgggtt tgctcttcat
      961 ttctttccag aaggatcctg ataactttgt taaggttcaa actaacctag gtgctactga
     1021 taagatgaat gaatacatca ctcacatagg tagtggactt tttacttgct ttggtggtgt
     1081 ggagaaagga ggctacattg gtcagaaatt attggaaggc taaaagctgg ttgcttgttt
     1141 tagctttgtc att
//
LOCUS       DAVLXH010000120         1043 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00028199
            SAMN33607166-rid17955573.denovo.121, whole genome shotgun sequence.
ACCESSION   DAVLXH010000120 DAVLXH010000000
VERSION     DAVLXH010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607166
            Sequence Read Archive: SRR23725544
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1043)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1043)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721421.1
            Genome Coverage       :: 115x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:42:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,210
            CDSs (total)                      :: 2,161
            Genes (coding)                    :: 2,023
            CDSs (with protein)               :: 2,023
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 73 of 138
            Pseudo Genes (incomplete)         :: 60 of 138
            Pseudo Genes (internal stop)      :: 40 of 138
            Pseudo Genes (multiple problems)  :: 31 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1043
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607166-rid17955573.denovo.121"
                     /strain="AUSMDU00028199"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1349"
     gene            180..362
                     /locus_tag="VYO11_002179"
     CDS             180..362
                     /locus_tag="VYO11_002179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001262531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ApaLI family restriction endonuclease"
                     /protein_id="HEV1596637.1"
                     /translation="MANDNKSHYLIYRVLGISFEEGENIDLYQNKGRFLYKYAGSFLE
                     EAAVLSFNEKFGTENT"
     gene            372..737
                     /locus_tag="VYO11_002180"
     CDS             372..737
                     /locus_tag="VYO11_002180"
                     /inference="COORDINATES: protein motif:HMM:NF021048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ApaLI family restriction endonuclease"
                     /protein_id="HEV1596638.1"
                     /translation="MPNSESTKPKTFEIDCLVGEKHAYEIKWWDATTDGDHITKEHTR
                     IKVIHNKGYIPIRLMFYYPNRTQAIKIQQTLETLYNGIGGKYYYGDSAWEHLRAVTGI
                     DLLSILTDIANKKTGVKSK"
     gene            734..1043
                     /locus_tag="VYO11_002181"
                     /pseudo
     CDS             734..1043
                     /locus_tag="VYO11_002181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811051.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
BASE COUNT          435 a          126 c          168 g          314 t
ORIGIN      
        1 tcaatattta aaaagaaaaa agctcaaaga atttattaaa ccatgttata atagatatag
       61 ctataatttt atttataaca agaggataga aatgaccgaa ttagaaagaa aaaatcgaaa
      121 aattagctaa gaaatattct gataacttaa acatcaaagt tcaagagaga gttcgtgaaa
      181 tggcaaatga taataagagc cattatttga tatacagagt tttaggtatt tcatttgaag
      241 aaggagaaaa tatcgatttg tatcaaaata aaggtcgttt tttatacaaa tatgctggtt
      301 catttttaga agaagctgca gtactatcct ttaacgaaaa atttggtaca gaaaatactt
      361 aaaaagttaa cattcctaat tctgaaagta caaaacctaa gacttttgaa attgattgtt
      421 tagtcggaga aaaacacgca tacgaaataa aatggtggga tgcaactaca gatggagacc
      481 atataactaa agaacacact agaataaaag ttattcataa caaaggatat ataccaattc
      541 ggttaatgtt ctactatcca aatagaactc aagctataaa aattcagcaa actttagaaa
      601 cattgtataa cggtattgga gggaaatatt attatggaga ttctgcctgg gaacatttaa
      661 gagcagtgac cggtattgat ttacttagta ttctaacaga tattgcaaat aaaaaaacag
      721 gggtaaaatc aaaatgacag tattaaaagg agataactta gaaatattaa aaactattga
      781 atcctcaagt attgatttaa tctatatgga ccctcctttc tttacacaga aaacccaaaa
      841 attatctaat aacaaaaata ttatgtattc attcgaagat acgtggactt cgattgagga
      901 ttacaaagaa tttttgtctg taagattaga agaatgcaaa agagtgctaa aaaatagtgg
      961 cagtatttcg ttcattgtga taaaattgca aatcatcata ttagattaat tttagataat
     1021 atctttggag cagatatgtt tca
//
LOCUS       DAVLXH010000121          930 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00028199
            SAMN33607166-rid17955573.denovo.122, whole genome shotgun sequence.
ACCESSION   DAVLXH010000121 DAVLXH010000000
VERSION     DAVLXH010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607166
            Sequence Read Archive: SRR23725544
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 930)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 930)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721421.1
            Genome Coverage       :: 115x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:42:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,210
            CDSs (total)                      :: 2,161
            Genes (coding)                    :: 2,023
            CDSs (with protein)               :: 2,023
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 73 of 138
            Pseudo Genes (incomplete)         :: 60 of 138
            Pseudo Genes (internal stop)      :: 40 of 138
            Pseudo Genes (multiple problems)  :: 31 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..930
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607166-rid17955573.denovo.122"
                     /strain="AUSMDU00028199"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1349"
     gene            <1..313
                     /locus_tag="VYO11_002182"
     CDS             <1..313
                     /locus_tag="VYO11_002182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HEV1596639.1"
                     /translation="KYFKTKFRNRILDYIRKQESQKRRYDKEPYEEVGEISHRISEGG
                     LWLDDYYLFHETLRDYRNKQSKEKQEELERVLSNERFRGRQRVLRDLRIVFKEFTIRT
                     H"
     gene            407..478
                     /locus_tag="VYO11_002183"
     tRNA            407..478
                     /locus_tag="VYO11_002183"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:440..442,aa:Glu,seq:ttc)
     gene            730..>930
                     /locus_tag="VYO11_002184"
     rRNA            730..>930
                     /locus_tag="VYO11_002184"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT          338 a          145 c          225 g          222 t
ORIGIN      
        1 gaaatatttc aaaaccaagt ttcgaaatcg aattttagac tatatccgta agcaggaaag
       61 tcagaagcgt agatacgata aagaacccta tgaagaagtg ggtgagatca gtcatcgtat
      121 aagtgagggg ggtctctggc tagatgatta ttatctcttt catgaaacac taagagatta
      181 tagaaacaaa caaagtaaag agaaacaaga agaactagaa cgcgtcttaa gcaatgaacg
      241 atttcgaggg cgtcaaagag tattaagaga cttacgcatt gtgtttaagg agtttactat
      301 ccgtacccat tagtaagtca tgcaaaaaaa atgaaaaaaa ttagaaaaag tagttgacaa
      361 agtttgaaaa ggctgtataa tagtaagagt tgaaaatagc aactcaggtc cgttggtcaa
      421 ggggttaaga caccgccttt tcacggcggt aacacgggtt cgaatcccgt acggactatg
      481 gtatgttgcg tcaggaccac ttgatgaaaa aaagtttaaa aaaacttaaa aatcttcaaa
      541 aaagtgttga caagtgaaag tggctgtgat atactaatat agttgtcgct tgagagaagc
      601 aagtgacaaa gacctttgaa aactgaacaa gacgaaccaa tgtgcagggc gctacaacgt
      661 aagttgtagt actgaacaat gaaaaaacaa taaatctgtc agtgacagaa atgagtgaga
      721 actcaaactt ttaatgagag tttgatcctg gctcaggacg aacgctggcg gcgtgcctaa
      781 tacatgcaag tagaacgctg aaggaggagc ttgcttctct ggatgagttg cgaacgggtg
      841 agtaacgcgt aggtaacctg cctggtagcg ggggataact attggaaacg atagctaata
      901 ccgcataaga gtagatgttg catgacattt
//
LOCUS       DAVLXH010000122          919 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00028199
            SAMN33607166-rid17955573.denovo.123, whole genome shotgun sequence.
ACCESSION   DAVLXH010000122 DAVLXH010000000
VERSION     DAVLXH010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607166
            Sequence Read Archive: SRR23725544
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 919)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 919)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721421.1
            Genome Coverage       :: 115x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:42:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,210
            CDSs (total)                      :: 2,161
            Genes (coding)                    :: 2,023
            CDSs (with protein)               :: 2,023
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 73 of 138
            Pseudo Genes (incomplete)         :: 60 of 138
            Pseudo Genes (internal stop)      :: 40 of 138
            Pseudo Genes (multiple problems)  :: 31 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..919
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607166-rid17955573.denovo.123"
                     /strain="AUSMDU00028199"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1349"
     gene            1..843
                     /locus_tag="VYO11_002185"
                     /pseudo
     CDS             1..843
                     /locus_tag="VYO11_002185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200043.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
     gene            836..>919
                     /locus_tag="VYO11_002186"
     CDS             836..>919
                     /locus_tag="VYO11_002186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV1596640.1"
                     /translation="MDRNIDQELVSIIIPTHNRYESLIRAVK"
BASE COUNT          338 a           82 c          195 g          304 t
ORIGIN      
        1 tatgttaaaa aaacttgaca agaatggatt tggaaaggtt aagacagtga taacatgcca
       61 tggatgggtt gaatataact taaaaaagaa attcttgact tattttgatt tttggacata
      121 ttctatggga gatgctttta tttgtgtatc tgaaactatg aaaaaaagat tggagagtat
      181 aataaaaaat aagaagatag ttgcaataaa taacggaatt aatgtatcaa atagcgattt
      241 agatgtagta ggtgttcaag actttaaaaa agaattttgt attccaaata acaaaaaatc
      301 atttgttatg ttgaaaggtt ggatccagaa aaaaggccgg atagattcct tgaatttgca
      361 gaaaaattat ttttagtcag agaagatgtg atttttatta tggctggaaa tggtagtatg
      421 tgggctgctt tgaaagaaaa aatttgccat ttgaaatgta gagataattt caggttactt
      481 ggtgaaatct atccagctac tatagtttac caaatatcgg atttattgta tattccttct
      541 gatacagaag gaatacctat gtgtgtttta gagtcaatgt cacaaggaac tccggtttta
      601 gctagtaatg ttggcgggtt aagtgaaatt attgaacata gggttgatgg atttttattt
      661 gagaaggaag atgttgaggg agtgtgtgct tgtgctaatt ttttactcaa tgattctgag
      721 tatttgaaat atataggtga gaatagtaaa tcaaaaataa gaaaacattt ttctgtgcaa
      781 aaaatgtttg tagaaaccat gagagtatat gatgaattat tagagaagag tagtcatgga
      841 taggaatata gatcaagaat tagtaagtat tataatacca acacataata ggtatgaatc
      901 tctgattaga gctgtgaaa
//
LOCUS       DAVLXH010000123          826 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00028199
            SAMN33607166-rid17955573.denovo.124, whole genome shotgun sequence.
ACCESSION   DAVLXH010000123 DAVLXH010000000
VERSION     DAVLXH010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607166
            Sequence Read Archive: SRR23725544
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 826)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 826)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721421.1
            Genome Coverage       :: 115x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:42:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,210
            CDSs (total)                      :: 2,161
            Genes (coding)                    :: 2,023
            CDSs (with protein)               :: 2,023
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 73 of 138
            Pseudo Genes (incomplete)         :: 60 of 138
            Pseudo Genes (internal stop)      :: 40 of 138
            Pseudo Genes (multiple problems)  :: 31 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..826
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607166-rid17955573.denovo.124"
                     /strain="AUSMDU00028199"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1349"
     gene            complement(<1..770)
                     /locus_tag="VYO11_002187"
     CDS             complement(<1..770)
                     /locus_tag="VYO11_002187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1596641.1"
                     /translation="MNLERFLKLSIYQMIVWCGIIFLDWVVKNYQVEVIQEFNLEIRN
                     RVATDISNSTYQEFHSKSSGTYLSWLNNDVQTLNDQAFKQLFLVIKGISGTIFAVVTL
                     NHYHWSLTVATLFSLMIMLLVPKIFASKMREVSLNLTNQNEAFLKSSETILNGFDVLA
                     SLNLLYVLPKKIKEAGILLKMVIQRKTTVETLAGAISFFLNIFFQISLVFLTGYLAIK
                     GIVKIGTIEAIGALTGVIFTALGELGGQLSSIIGTKPI"
BASE COUNT          293 a          150 c          116 g          267 t
ORIGIN      
        1 aaaataggct tcgtaccaat aatagaggat aattgacctc ctaattcacc tagcgctgta
       61 aaaataacac ctgttagtgc tcctattgct tcaatagtac caattttcac tattcctttt
      121 attgcaagat agcctgttaa aaaaacgaga gatatctgaa aaaaaatatt gagaaagaag
      181 ctaatagcgc ctgctaacgt ttctacagtt gtctttcttt gtataaccat ctttaataaa
      241 attcctgctt ctttaatttt cttaggcaat acatataaaa gattcaagga cgctaacaca
      301 tcaaatccat tcaatatagt ctcactagat tttaaaaaag cttcattttg gttagttaaa
      361 tttagactaa cttctcgcat tttcgatgca aagatttttg gtacaagtag cataatcatt
      421 aatgaaaaca aggtggctac agtcaatgac caatgatagt gattaagagt cacaactgca
      481 aatatagtac cagaaattcc ttttattact aaaaaaagtt gtttaaaagc ctgatcattt
      541 aaagtctgaa catcattatt tagccacgaa agatatgttc ctgatgattt actatgaaat
      601 tcttgatagg tagagttaga gatgtctgtg gcaactctat ttcgaatctc tagattaaac
      661 tcttggatca cttcaacctg ataatttttc actacccagt caaggaatat tatcccacac
      721 cagacaatca tttggtagat tgacaatttc aaaaaccgct ctaaattcat cgcaattaat
      781 tcattcaaca ccagagcatt aatagttgct gcataaatta gcaata
//
LOCUS       DAVLXH010000124          812 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00028199
            SAMN33607166-rid17955573.denovo.125, whole genome shotgun sequence.
ACCESSION   DAVLXH010000124 DAVLXH010000000
VERSION     DAVLXH010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607166
            Sequence Read Archive: SRR23725544
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 812)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 812)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721421.1
            Genome Coverage       :: 115x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:42:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,210
            CDSs (total)                      :: 2,161
            Genes (coding)                    :: 2,023
            CDSs (with protein)               :: 2,023
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 73 of 138
            Pseudo Genes (incomplete)         :: 60 of 138
            Pseudo Genes (internal stop)      :: 40 of 138
            Pseudo Genes (multiple problems)  :: 31 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..812
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607166-rid17955573.denovo.125"
                     /strain="AUSMDU00028199"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1349"
     gene            complement(1..812)
                     /locus_tag="VYO11_002188"
                     /pseudo
     CDS             complement(1..812)
                     /locus_tag="VYO11_002188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT          245 a          148 c          173 g          246 t
ORIGIN      
        1 cctgcttaag attgtcctcg ataagttcga aaaatttctc tggttcctta ttctggaagt
       61 gaaaaagcaa gagctgatag agctgatagt ggtgtttcaa gtcttgtgaa taactcaaaa
      121 gcttgtttaa aatctcttta ttggttaaat gcatacgaaa agtaggacga taaaatcgct
      181 tatcactcag tttacggcta tcctgttgta tgagcttcca gtagcgcttg atagccttgt
      241 attcatggga ttttcgatga aactgattca tgatttgaac acgcacacga ctcatagcac
      301 ggctaagatg ttgcacaatg tgaaagcgat caagaacgat tttagcattc gggagtgaaa
      361 cagtctggga gactgtttca gcctgagcct agaaatttga aagcgaagct gtttagccaa
      421 gtcatagtaa gggctaaaca tatccatagt aatgattttg acgcgacatc ggacggctct
      481 atcatattta agaaagtgat ctcggatgac agcttgtgtt ctaccttcaa gaacagtgat
      541 gatatcgagc ttttcaaaat cttgcgcaat aaagctcatc tccatctccc gattgaaaca
      601 gtcactcccc ggactgtttc aacgtcccaa gacataatct taggcagatt tctaaaatta
      661 cactcaaagt ggaagtcatt gagctttcga atgacagttg aagttgagat ggaaagctga
      721 tgggcaatat cagtcataga aatcttttca attaactttt gagcaatctt ttggttgatg
      781 atacgaggga tttgatgatt cttcttgacg at
//
LOCUS       DAVLXH010000125          775 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00028199
            SAMN33607166-rid17955573.denovo.126, whole genome shotgun sequence.
ACCESSION   DAVLXH010000125 DAVLXH010000000
VERSION     DAVLXH010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607166
            Sequence Read Archive: SRR23725544
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 775)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 775)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721421.1
            Genome Coverage       :: 115x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:42:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,210
            CDSs (total)                      :: 2,161
            Genes (coding)                    :: 2,023
            CDSs (with protein)               :: 2,023
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 73 of 138
            Pseudo Genes (incomplete)         :: 60 of 138
            Pseudo Genes (internal stop)      :: 40 of 138
            Pseudo Genes (multiple problems)  :: 31 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..775
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607166-rid17955573.denovo.126"
                     /strain="AUSMDU00028199"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1349"
     gene            1..645
                     /locus_tag="VYO11_002189"
                     /pseudo
     CDS             1..645
                     /locus_tag="VYO11_002189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000433508.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(680..>775)
                     /locus_tag="VYO11_002190"
     CDS             complement(680..>775)
                     /locus_tag="VYO11_002190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
                     /protein_id="HEV1596642.1"
                     /translation="KTWVHIKKNLKKVLPSCNTFYEALLSCSCFN"
BASE COUNT          250 a          167 c          124 g          234 t
ORIGIN      
        1 gacattgatc atcagttgtc tatttcaact tcaactgtca ttcgcaagat caatgatttt
       61 cactttgagc atgatttttc gcgtcttcct gagattatgt cctaggacgt tgaaacagtc
      121 cggggagtga ctgtttcaat cgggagatgg agatgagctt tattgctcag gactttgata
      181 aactcaatat cataactgtt cttgagagca gaacacaagc catcatccga aatcccatga
      241 atacaaggct atcaagcgct actggaagct cattcaacaa gatagtcaga aactgagtga
      301 taaacgattt tatcgcccta cttttcgtat gcacttgact aataaagaaa ttctagataa
      361 acttttgagc tattccgaag actttaaaca ccactataat ctctatcagc tcttgctttt
      421 ccacctctgt ttcagacttt gtttaaaacc ttcctcaaag ataaagagaa aatcgtcaac
      481 gcccttcaat taccttattc caacgccaaa ctggaagcca ccaataatct catcaaactt
      541 atcaagcaca atgcctttgg ttttaggaac tttgaaaact tcaaaaaaga aaggacgaaa
      601 tttgtccttt ctagatcttc gctttcttca acccactaca gttgacaaag aaccgaaaaa
      661 tgtctcgcct ctaatatagt caattgaaac aagaacaaga caaaagagcc tcataaaagg
      721 tattgcaact tggtaatacc tttttgaggt tctttttgat atgaacccat gtttt
//
LOCUS       DAVLXH010000126          748 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00028199
            SAMN33607166-rid17955573.denovo.127, whole genome shotgun sequence.
ACCESSION   DAVLXH010000126 DAVLXH010000000
VERSION     DAVLXH010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607166
            Sequence Read Archive: SRR23725544
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 748)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 748)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721421.1
            Genome Coverage       :: 115x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:42:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,210
            CDSs (total)                      :: 2,161
            Genes (coding)                    :: 2,023
            CDSs (with protein)               :: 2,023
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 73 of 138
            Pseudo Genes (incomplete)         :: 60 of 138
            Pseudo Genes (internal stop)      :: 40 of 138
            Pseudo Genes (multiple problems)  :: 31 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..748
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607166-rid17955573.denovo.127"
                     /strain="AUSMDU00028199"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1349"
     gene            <1..628
                     /locus_tag="VYO11_002191"
     CDS             <1..628
                     /locus_tag="VYO11_002191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000677523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1596643.1"
                     /translation="EGEVLLDNKSINSYKEKDLVKHIAILPQSPIIPESITVADLVSR
                     GRFPYRKPFKSLGKDDLEIINRSMVKANVEDLANNLVEELSGGQRQRVWIALALAQDT
                     SILLLDEPTTYLDISYQIELLDLLTDLNQKYKTTICMILHDINLTARYADYLFAIKEG
                     KLVAEGKPEDILNDKLVKDIFNLEAKIIRDPISNSPLMIPIGKHHVNS"
BASE COUNT          282 a          130 c          123 g          213 t
ORIGIN      
        1 agagggagaa gtattgcttg ataataaatc aattaattct tataaagaaa aagatttagt
       61 aaaacacata gctatattac ctcaatctcc aataatccct gaatcaataa cagtagctga
      121 tcttgtaagc cgtggtcgtt tcccctacag aaagcctttt aagagtcttg gaaaagatga
      181 ccttgaaata ataaacagat caatggttaa ggccaatgtt gaagatctag caaataacct
      241 agttgaagaa ctttctgggg gtcaaaggca aagagtatgg atagctctag ccctagccca
      301 agatacaagt atcctacttt tagatgagcc aactacttac ttggatatct catatcaaat
      361 agaactatta gacctcttga ctgatctaaa ccaaaaatat aagacaacca tttgcatgat
      421 tttgcacgat ataaatctaa cagcaagata cgctgattac ctatttgcaa ttaaagaagg
      481 taaacttgtt gcagagggaa agcctgaaga tatactaaat gataaactag ttaaagatat
      541 ctttaatctt gaagcaaaaa ttatacgtga ccctatttcc aattcgcctc taatgattcc
      601 tattggcaag caccatgtta actcttaata attgaatatt ggaattcatt taaaagtcgc
      661 aaattttgaa ctgaccctca aaagttaggc caaaaaacta actaaaggag gtcagttttt
      721 taatggcaaa tacagcacag aatttaag
//
LOCUS       DAVLXH010000127          726 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00028199
            SAMN33607166-rid17955573.denovo.128, whole genome shotgun sequence.
ACCESSION   DAVLXH010000127 DAVLXH010000000
VERSION     DAVLXH010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607166
            Sequence Read Archive: SRR23725544
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 726)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 726)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721421.1
            Genome Coverage       :: 115x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:42:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,210
            CDSs (total)                      :: 2,161
            Genes (coding)                    :: 2,023
            CDSs (with protein)               :: 2,023
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 73 of 138
            Pseudo Genes (incomplete)         :: 60 of 138
            Pseudo Genes (internal stop)      :: 40 of 138
            Pseudo Genes (multiple problems)  :: 31 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..726
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607166-rid17955573.denovo.128"
                     /strain="AUSMDU00028199"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1349"
     gene            <1..665
                     /locus_tag="VYO11_002192"
     CDS             <1..665
                     /locus_tag="VYO11_002192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEV1596644.1"
                     /translation="SNEDLGATNARNIGIKNSRGKYISFLDDDDEYMPDRILKLMACF
                     KKSRMKNLALVYSYGIIIYPNGTREEEKTDFVGNPLFVQMVHNIAGTSFWLCKKEVLE
                     LINGFEKIDSHQDGVVLLKLLAQGYQIDIVREFLVNYYAHSKENGITGVTQKTINADE
                     EYYNYCRKYFNLLSFNERILVTKKYYSLNIKRLLLIGDKCKALKVIKKAREEKIFNEF
                     LF"
BASE COUNT          274 a           74 c          137 g          241 t
ORIGIN      
        1 taagtaatga agatttaggt gcaactaatg ccagaaacat aggtataaaa aattctagag
       61 gtaagtatat atcattttta gacgatgatg atgaatatat gccagatcga attttaaagt
      121 tgatggcttg ttttaaaaag agtagaatga agaatttagc tttagtttat agttatggaa
      181 taataattta tccaaatggt acacgagaag aggagaagac cgattttgtt ggaaatccct
      241 tgtttgttca aatggttcac aatatagcag gtacgtcatt ttggttgtgt aaaaaagagg
      301 tgctagaatt aattaatggt tttgagaaaa tagattcaca tcaggacggt gttgttttat
      361 taaaactact tgctcaagga taccaaattg atatagtgcg agaattcttg gtgaattact
      421 acgctcacag taaagaaaac ggtatcactg gagtgacaca aaaaacaatt aatgcagatg
      481 aagaatatta taattactgt aggaaatatt ttaatttatt gagtttcaac gagagaatat
      541 tggttacaaa gaaatattat tctttaaaca taaagcggtt actattaata ggagacaaat
      601 gcaaggcttt aaaagtaatc aagaaggcaa gagaagaaaa aatttttaac gaatttcttt
      661 tttgaaatat atgttattat atcattttgg ctttttctat tgtatatatg acaactatgt
      721 tcaatt
//
LOCUS       DAVLXH010000128          677 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00028199
            SAMN33607166-rid17955573.denovo.129, whole genome shotgun sequence.
ACCESSION   DAVLXH010000128 DAVLXH010000000
VERSION     DAVLXH010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607166
            Sequence Read Archive: SRR23725544
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 677)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 677)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721421.1
            Genome Coverage       :: 115x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:42:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,210
            CDSs (total)                      :: 2,161
            Genes (coding)                    :: 2,023
            CDSs (with protein)               :: 2,023
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 73 of 138
            Pseudo Genes (incomplete)         :: 60 of 138
            Pseudo Genes (internal stop)      :: 40 of 138
            Pseudo Genes (multiple problems)  :: 31 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..677
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607166-rid17955573.denovo.129"
                     /strain="AUSMDU00028199"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1349"
     gene            93..455
                     /locus_tag="VYO11_002193"
     CDS             93..455
                     /locus_tag="VYO11_002193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-export chaperone SecB"
                     /protein_id="HEV1596645.1"
                     /translation="MLEVGLNFLISLFTFTFDILYPIVKVGHTDDYSHGAVKLSVSLV
                     DKDAMKKISVTVIGYFEINIDENITDILYVNGTAILYHYLRSIVSIVSAIDSSEAMLL
                     PTINVLELLDKSQPFEEE"
BASE COUNT          224 a           87 c          123 g          243 t
ORIGIN      
        1 cgtcagttcc atctacaacc tcaaaacagt gttttgagca acctgaggct agtttcctag
       61 tttgctcttt ggttttcatt gagtataaca gattgttaga agttggttta aatttcctaa
      121 tcagtttgtt cacatttacc ttcgatatat tatatcccat agttaaggtt ggtcatacag
      181 atgattatag tcatggagcc gtaaaactta gtgtttcttt agttgacaaa gatgccatga
      241 aaaaaatatc tgtaactgta ataggatatt ttgaaataaa tatagatgaa aatatcaccg
      301 atattctata cgtaaatggt actgctattc tttatcatta tttacgttct attgtttcaa
      361 tagtttcggc aattgatagc agtgaagcaa tgttgctacc taccattaat gttttagagt
      421 tactagataa atctcaacct tttgaagaag aataatttat tagctcacta aattgagggt
      481 aaggaaaagt aaaatcagta agaaaaatgt cttgcattat acagcaacct tttgggaatg
      541 agtagatgga ttgaataaaa ttttattaag agtggatgat ttatctgtag attattattg
      601 gacagttagt cttgaagtag tctaagaatt aggttataat cagtagaatc cttgctaata
      661 atgaggaggt tagttta
//
LOCUS       DAVLXH010000129          540 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00028199
            SAMN33607166-rid17955573.denovo.130, whole genome shotgun sequence.
ACCESSION   DAVLXH010000129 DAVLXH010000000
VERSION     DAVLXH010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607166
            Sequence Read Archive: SRR23725544
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 540)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 540)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721421.1
            Genome Coverage       :: 115x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:42:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,210
            CDSs (total)                      :: 2,161
            Genes (coding)                    :: 2,023
            CDSs (with protein)               :: 2,023
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 73 of 138
            Pseudo Genes (incomplete)         :: 60 of 138
            Pseudo Genes (internal stop)      :: 40 of 138
            Pseudo Genes (multiple problems)  :: 31 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..540
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607166-rid17955573.denovo.130"
                     /strain="AUSMDU00028199"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1349"
     gene            complement(<1..>540)
                     /locus_tag="VYO11_002194"
     CDS             complement(<1..>540)
                     /locus_tag="VYO11_002194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000049683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="polysaccharide biosynthesis C-terminal
                     domain-containing protein"
                     /protein_id="HEV1596646.1"
                     /translation="GIQASAIISVAYKIPQIFSTISAIFIQSWQISAIKIQEEKEGNT
                     FISKMLLYYNALLLIIASGIILFVKPISNILFGASFYSAWTLVPFLIISSLFNAISGY
                     IGAIMGAKMDTKNIAKSALVGMIANVFLNIVLTFLMGLQGITISTMIASFLIFYMRKD
                     SVEEIAPETYRAIYLSWFL"
BASE COUNT          201 a           94 c           75 g          170 t
ORIGIN      
        1 acaaaaacca cgaaagataa atagctctat atgtttctgg agcaatttct tcaacactat
       61 cttttctcat ataaaaaata agaaaactag ctatcatagt tgagattgta atcccctgta
      121 gtcccattaa aaatgttaat acaatattta aaaaaacatt agctatcatt ccaaccaaag
      181 cagatttagc aatattttta gtatccattt tagcgcccat tatcgctcct atataacccg
      241 aaatcgcatt aaacaaactg ctaataatta aaaacggtac aagcgtccac gctgaataaa
      301 atgaagctcc gaagagtata ttagagattg gttttacaaa tagaatgata ccgctcgcta
      361 taatcagcaa gagtgcatta taatataaaa gcatttttga tataaaggtg ttaccttctt
      421 tttcttcctg aatttttatt gcagatattt gccacgattg aatgaatata gcgctaattg
      481 tggaaaaaat ttgtggaatc ttataagcaa ctgaaataat cgcactagct tgtataccta
//
LOCUS       DAVLXH010000130          470 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00028199
            SAMN33607166-rid17955573.denovo.131, whole genome shotgun sequence.
ACCESSION   DAVLXH010000130 DAVLXH010000000
VERSION     DAVLXH010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607166
            Sequence Read Archive: SRR23725544
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 470)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 470)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721421.1
            Genome Coverage       :: 115x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:42:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,210
            CDSs (total)                      :: 2,161
            Genes (coding)                    :: 2,023
            CDSs (with protein)               :: 2,023
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 73 of 138
            Pseudo Genes (incomplete)         :: 60 of 138
            Pseudo Genes (internal stop)      :: 40 of 138
            Pseudo Genes (multiple problems)  :: 31 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..470
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607166-rid17955573.denovo.131"
                     /strain="AUSMDU00028199"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1349"
     gene            1..470
                     /locus_tag="VYO11_002195"
                     /pseudo
     CDS             1..470
                     /locus_tag="VYO11_002195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT          161 a           85 c           89 g          135 t
ORIGIN      
        1 aaagctatgg gctacactcg aaaaaaagaa ccacacctac tatgaacaag acccagaaaa
       61 agtagcctta tttcttaaga attttaatag tttaaagcac ctagcacctg tttagattga
      121 cgaaacagga ttcgatactt atttttatcg agaatatggt cgctcattaa aaggtcagtt
      181 aagaagaggc aaagtatctg gaagaagata tcagaggatt tctttggttg caggtctaac
      241 aaatggtgaa ttaatcgctc caatgactta cgaagagacg atgacgagcg acttttttga
      301 agtatggttt cagaaatttc tcttaccaac attaaccaca ccatcggtta ttattatgga
      361 taatgcaaga ttccatagaa tgggtaagct agaactcttg tgtgaagagt ttgggcataa
      421 acttttacct cttcctccct actcacctga gtacaatcct attgagaaaa
//
LOCUS       DAVLXH010000131          401 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00028199
            SAMN33607166-rid17955573.denovo.132, whole genome shotgun sequence.
ACCESSION   DAVLXH010000131 DAVLXH010000000
VERSION     DAVLXH010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607166
            Sequence Read Archive: SRR23725544
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 401)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 401)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721421.1
            Genome Coverage       :: 115x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:42:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,210
            CDSs (total)                      :: 2,161
            Genes (coding)                    :: 2,023
            CDSs (with protein)               :: 2,023
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 73 of 138
            Pseudo Genes (incomplete)         :: 60 of 138
            Pseudo Genes (internal stop)      :: 40 of 138
            Pseudo Genes (multiple problems)  :: 31 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..401
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607166-rid17955573.denovo.132"
                     /strain="AUSMDU00028199"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1349"
     gene            1..>401
                     /locus_tag="VYO11_002196"
     CDS             1..>401
                     /locus_tag="VYO11_002196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV1596647.1"
                     /translation="MEQLHFITKLLDIKDPNIQILDIINKDTHKEIIAKLDYDAPSCP
                     ECGSQMKKYDFQKPSKIPYLETTGMPTRILLRKRRFKCYHCSKMMVAETPLVKKNHQI
                     PRIINQKIAQKLIEKISMTDITHQLAISTSTV"
BASE COUNT          146 a           95 c           56 g          104 t
ORIGIN      
        1 atggaacaat tacattttat cacaaaactg ctcgatatta aagacccaaa tatccagatt
       61 ttagacatca tcaataagga tacacacaag gaaatcatcg ccaaactgga ctacgacgcc
      121 ccatcttgcc ctgagtgcgg aagtcaaatg aagaaatatg actttcaaaa accttctaaa
      181 atcccttacc tcgaaacaac tggtatgcct actagaattc tccttagaaa acgccgtttc
      241 aagtgctatc actgttcaaa aatgatggtt gctgagactc ccctggtaaa gaaaaatcac
      301 caaatccctc gtatcatcaa ccaaaaaatt gctcaaaagt taattgaaaa aatttctatg
      361 actgatatta cccatcagct ggccatttca acttcaactg t
//
LOCUS       DAVLXH010000132          380 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00028199
            SAMN33607166-rid17955573.denovo.133, whole genome shotgun sequence.
ACCESSION   DAVLXH010000132 DAVLXH010000000
VERSION     DAVLXH010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607166
            Sequence Read Archive: SRR23725544
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 380)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 380)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721421.1
            Genome Coverage       :: 115x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:42:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,210
            CDSs (total)                      :: 2,161
            Genes (coding)                    :: 2,023
            CDSs (with protein)               :: 2,023
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 73 of 138
            Pseudo Genes (incomplete)         :: 60 of 138
            Pseudo Genes (internal stop)      :: 40 of 138
            Pseudo Genes (multiple problems)  :: 31 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..380
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607166-rid17955573.denovo.133"
                     /strain="AUSMDU00028199"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1349"
     gene            <1..>380
                     /locus_tag="VYO11_002197"
     CDS             <1..>380
                     /locus_tag="VYO11_002197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000927608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1596648.1"
                     /translation="YLHIAYATSNNGSQGFSTTDSTNKTYIGTYTDYTQSDSTDYRVY
                     KWTLIKGADGTGISNVTNYYLATTVSTGITRTSAGWTTTPQPITSDKRYLWNYRVELY
                     TNGTSKTTEPAVIGVHGEKGERGL"
BASE COUNT          137 a           74 c           78 g           91 t
ORIGIN      
        1 tacttacata tagcttacgc cacatcaaat aacggctcac aaggcttctc aactactgac
       61 agtacaaata aaacgtatat cggaacatac acagattaca ctcagtcaga tagtacagat
      121 tacagagtgt ataagtggac gttgataaaa ggggcagatg gtactggtat ttctaatgta
      181 actaattatt atttagctac tacagtctca acaggtatca caagaacaag cgcagggtgg
      241 acaactacgc cacaacctat cacatcagac aagcgttatt tatggaatta tcgagttgag
      301 ctatacacaa acggtacaag taagacaaca gagcctgctg ttattggtgt gcacggggaa
      361 aaaggagaac gtggattaca
//
LOCUS       DAVLXH010000133          368 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00028199
            SAMN33607166-rid17955573.denovo.134, whole genome shotgun sequence.
ACCESSION   DAVLXH010000133 DAVLXH010000000
VERSION     DAVLXH010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607166
            Sequence Read Archive: SRR23725544
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 368)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 368)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721421.1
            Genome Coverage       :: 115x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:42:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,210
            CDSs (total)                      :: 2,161
            Genes (coding)                    :: 2,023
            CDSs (with protein)               :: 2,023
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 73 of 138
            Pseudo Genes (incomplete)         :: 60 of 138
            Pseudo Genes (internal stop)      :: 40 of 138
            Pseudo Genes (multiple problems)  :: 31 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..368
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607166-rid17955573.denovo.134"
                     /strain="AUSMDU00028199"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1349"
     gene            <1..>368
                     /locus_tag="VYO11_002198"
     CDS             <1..>368
                     /locus_tag="VYO11_002198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1596649.1"
                     /translation="PAPSNPIDEKLVKEAVRKVGDGYVFEENGVSRYIPAKDLSAETA
                     AGIDSKLAKQESLSHKLGAKKTDLPSSDREFYNKAYDLLARIHQDLLDNKGRQVDFEA
                     LDNLLERLKDVSSDKVKLVD"
BASE COUNT          123 a           64 c           85 g           96 t
ORIGIN      
        1 accagctcca agcaatccaa ttgatgagaa attggtcaaa gaagctgttc gaaaagtagg
       61 cgatggttat gtctttgagg agaatggagt ttctcgttat atcccagcca aggatctttc
      121 agcagaaaca gcagcaggca ttgatagcaa actggccaag caggaaagtt tatctcataa
      181 gctaggagct aagaaaactg acctcccatc tagtgatcga gaattttaca ataaggctta
      241 tgacttacta gcaagaattc accaagattt acttgataat aaaggtcgac aagttgattt
      301 tgaggctttg gataacctgt tggaacgact caaggatgtc tcaagtgata aagtcaagtt
      361 agtggatg
//
LOCUS       DAVLXH010000134        10072 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00028199
            SAMN33607166-rid17955573.guided.066, whole genome shotgun sequence.
ACCESSION   DAVLXH010000134 DAVLXH010000000
VERSION     DAVLXH010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607166
            Sequence Read Archive: SRR23725544
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10072)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10072)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721421.1
            Genome Coverage       :: 115x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:42:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,210
            CDSs (total)                      :: 2,161
            Genes (coding)                    :: 2,023
            CDSs (with protein)               :: 2,023
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 73 of 138
            Pseudo Genes (incomplete)         :: 60 of 138
            Pseudo Genes (internal stop)      :: 40 of 138
            Pseudo Genes (multiple problems)  :: 31 of 138
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10072
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607166-rid17955573.guided.066"
                     /strain="AUSMDU00028199"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1349"
     gene            1..302
                     /locus_tag="VYO11_002199"
                     /pseudo
     CDS             1..302
                     /locus_tag="VYO11_002199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000224688.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            986..1147
                     /locus_tag="VYO11_002200"
     CDS             986..1147
                     /locus_tag="VYO11_002200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005761276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1596650.1"
                     /translation="MDNDWNGLADLIANLIAKYAGALDLDNLPDPTPAKNQEMKNSFD
                     MAKTQIETD"
     gene            1239..2923
                     /locus_tag="VYO11_002201"
                     /pseudo
     CDS             1239..2923
                     /locus_tag="VYO11_002201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031864.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
     gene            3191..3757
                     /locus_tag="VYO11_002202"
     CDS             3191..3757
                     /locus_tag="VYO11_002202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1596651.1"
                     /translation="MVILELYQNDYSKDLVAFDSIEDGKAFVAQIPGYTLETEDGFEV
                     EYFNPKNIPDYMEIIFNGNIVPLSKFMFDPEENVNIIWKEISNLSLKNDRVIEGYSKI
                     DAYVVNNHEVKAYVETRETNYRKAKDFLESRGYEIDRSFFGSEDGEAILYRKKGIEVW
                     HFLCHLDPMFVEIEDVEGYVKEEVGEIQ"
     gene            4079..4267
                     /locus_tag="VYO11_002203"
     CDS             4079..4267
                     /locus_tag="VYO11_002203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopG family transcriptional regulator"
                     /protein_id="HEV1596652.1"
                     /translation="MATDKNRIMISLDDKNLEKLENLVEDARDRRGMRLTKSQVIELL
                     LNTVDYFDDIMGAIYSKK"
     gene            4329..5087
                     /locus_tag="VYO11_002204"
     CDS             4329..5087
                     /locus_tag="VYO11_002204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HEV1596653.1"
                     /translation="MVVYIRQSKLPSEVSINKYNAQVGAYLQGEEAVLYQSFSEIKEL
                     TSEDIVVDYIMETRALLKMMGLNVPVHDYPIELKEFYGRKIYAGILGEIVNIPDNWGK
                     FIKPKAGSKVFTGRVVNGTHDLIGIGLPFDYPIWISEVVEFIAEWRCFVLDGRVLDVR
                     PYTGDYHAQFDASVIDEAISCWKDAPIAYGLDIGVTRDGRTLVVEVNDGYALGNYGLS
                     PLKSINFHRARWKEMVKPYFEKNEIFKIQQDVVF"
     gene            5145..5606
                     /locus_tag="VYO11_002205"
     CDS             5145..5606
                     /locus_tag="VYO11_002205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000901908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="HEV1596654.1"
                     /translation="MLGAIIGDIVGSVYEWNNIKTKDFPLFRKDCFFTDDTVMTCAVA
                     EAIMNGGQKDDFIDAMKKYGRMYPNADYGARFNAWLNSDNREPYNSFGNGSAMRISPC
                     AWIMDCGFYAKTGIWPSSRGLTSLSAEVTHNHPEGVKGAMATADAIFLCRF"
     gene            5640..5999
                     /locus_tag="VYO11_002206"
     CDS             5640..5999
                     /locus_tag="VYO11_002206"
                     /inference="COORDINATES: protein motif:HMM:NF015692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="HEV1596655.1"
                     /translation="MNDNPIECKRRIKDYIEKEYDYNLSQTLDEIRPNYRFNETCQET
                     VPQAIIAFLESRDFEDAIRNAISLGGDSDTLAAITCSIAEAAYGIPDWIKDKAYSYLD
                     EPLKDVVRRWENRIKVY"
     gene            6111..6995
                     /locus_tag="VYO11_002207"
     CDS             6111..6995
                     /locus_tag="VYO11_002207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HEV1596656.1"
                     /translation="MKKAMVIINPTSGGEKALDYKEKLENKAKEYFEYVETKITEKAL
                     DATHFAEEASREQYDAVVVFGGDGTVNEVISGIDERDYIPKLGIIPGGTGNLITKLLE
                     INQDIDGAIDELDFDLTNKIDIGKANDNYFGYIFSIGSLPEAIHNVEIEDKTKQGILA
                     YAVNTMKSVMTDQVFNIKVETENGNYVGEASHVLVLLTNYFADKKIFEENKDGYANIL
                     ILKDASIFSKLSVIPDLLKGDVIANDNIEYIKARNIKISSDSELESDVDGDKSDNLPV
                     EIKVLAQRVEVFSKPKED"
     gene            7158..8897
                     /locus_tag="VYO11_002208"
     CDS             7158..8897
                     /locus_tag="VYO11_002208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glycosidase"
                     /protein_id="HEV1596657.1"
                     /translation="MELSAIYHRTESEYAYLYKDKKLHIRIRTKKGDIESINLHYGDP
                     FIFMEEFYQDTKEMVKITSGTLFDHWQVEVSVDFARIQYLFELRDTEGQNILYGDKGC
                     VENSLENLHAIGNGFKLPYLHEIDACKVPDWVSNTVWYQIFPERFANGNALLNPEGTL
                     DWDSSVTPKSDDFFGGDLQGIIDHMDYLQDLGITGLYLCPIFESTSNHKYNTTDYFEI
                     DRHFGDKETFRELVDQAHHRGMKVMLDAVFNHIGSQSLQWKNVVKNGEQSAYKDWFHI
                     QQFPVTTEKLVNKRDLPYHVFGFEDYMPKLNTANPEVKNYLLKVATYWIEEFNIDAWR
                     LDVANEIDHQFWKDFRKAVLAKNPDLYILGEVWHTSQPWLNGDEFHAVMNYPLSDSIK
                     DYFLRGIKKTDQFIDEINGESMYYKQQISEVMFNLLDSHDTERILWTANEDVQLVKSA
                     LAFLFLQKGTPCIYYGTELALTGGPDPDCRRCMPWERVSSDNDMLNFMKRLIKIRKYA
                     SVIISHGKYSLQEIKSDLVALEWKYEGRILKAIFNQSTEDYLLEKEAVALASNCQELE
                     NQLVISPDGFVIF"
     gene            9172..9474
                     /locus_tag="VYO11_002209"
     CDS             9172..9474
                     /locus_tag="VYO11_002209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1596658.1"
                     /translation="MGAARDFLELINHKGLPLFNPLVGDSHVNNRQEYDNTGSGNLQP
                     EKWNETAKQLYNVIMWLIILWNAKPDTPLFNFKDEVIKYKTYEPFESSIKLVSINE"
     gene            9530..9958
                     /locus_tag="VYO11_002210"
     CDS             9530..9958
                     /locus_tag="VYO11_002210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1596659.1"
                     /translation="MDGITKDFIKTAKLMKQLWPQLTDKEAIDEVKKYTNGKNTAIFT
                     EVEGDTIVGLALCSLRFDYVEGCKYSPVGFLEGIIVDEEYRLKDIAKNLCTKCEEWAK
                     NKGCKEFASDCTLTNTDSIRFHLNIGFQEANRIIHFKKKL"
BASE COUNT         3605 a         1381 c         2108 g         2978 t
ORIGIN      
        1 tggaaagata tagagataga taaagagaga gggagagata gataaaaagt ccacccccat
       61 ttttttatgg agaattcaaa aatgtaaggt taagcaaaga agaatataaa aatctaaaag
      121 aaaaattaaa ctcacacaca gatataatga taaataaact atccagatac atggaaagca
      181 gtggtaagac ctatcaaaac cactatgtga caatcttaaa atggtatgaa gaagataaag
      241 acaaactaag acagaaaggt ttaaataaaa aaatgaatta tgatgtagga gaatctttat
      301 agataaaaag aggtggaaag gcactattaa agactttaag tctaaaaagg tatcaaagta
      361 tgccagagat aaaaaaatat aaatatgaca ctttaaaggt gattagaaaa ttaaagaaat
      421 gctagaagac ttttagatga cagttaccaa gagggtctaa ttttcactgc tacttatgca
      481 gtgggaattg gaccttttta tataagcaaa ttctatttca aaattggtta ccaagaaaga
      541 cttcttttca ctgttaagta taagagggta atttatagaa ttttgttaca ttaagataaa
      601 tattttctga tggtcaaatt ttaaaaagat taataattct cgataaattt tgaaccttaa
      661 caattgaata gaccaagaca agacgttaat tatttttgga gcgtaataac ctatccgtca
      721 agatctttcg gctgaataat tcggcaaaaa aagttctgct aagtaaaaag aaagtgagcg
      781 ataagtaaga gtttgaatat agggagggat accctatccg ctatgaagaa aatgaggata
      841 atgatacttc taaggttgaa gccggctcat ccggaataga ggcggaggtg agattcctat
      901 gttgctaatc caaagcactt gtcaatgtca aaaaacttaa ttaaacaaat aattattaga
      961 tataaaactt tagaggaggt atatattgga caatgactgg aatggattgg ctgatttaat
     1021 agcaaatctg attgcaaaat atgctggtgc tttagattta gataatctac ccgatccaac
     1081 gccagcaaaa aatcaagaga tgaaaaatag ttttgacatg gcaaaaacac aaattgagac
     1141 ggactaataa aagtgttata atatacttga aatgatagtc caaacttaaa ttaaaaaaat
     1201 tatatatgat atagaaaaat tatattgagg ttaatactat gtcaaaagaa aaaataaaag
     1261 tatacctcta tacacgagta tctacgtcaa tacagataga ggggtattcg ttagaggcac
     1321 aaaaatcacg aatgaaagct tttgctattt acaacgatta tgaaattgtt ggagagtatg
     1381 aagatgccgg gaagtctggc aagtctattg aaggtagaat acagttcaat cgaatgatgg
     1441 aagatataaa atctggaaaa gatggagtat cttttgttct tgtgtttaag ttatcaagat
     1501 ttgcaagaaa tgccgctgat gttctttcta cacttcagat aatgcaggat tatggagtta
     1561 atcttatctg cgttgaagat ggcattgatt catctaaaga tgctgggaaa ctaatgattt
     1621 ctgttttatc agctgtggct gaaatagaaa gagaaaacat ccgtattcaa acaatggaag
     1681 attgcattca aaaagcaagg gaaggaaaat ggaatggtgg ctttgctccg tatggatata
     1741 aacttgaaga cggcaagctg tttataaatg aggaagaggc agttgcaata agaacgattt
     1801 tcgaccagta tgtaaatact acgataggag ccaatgggat atctaaatac ttagagaatc
     1861 atggaattag aaaaatccca agacagaatg gtaagaatcc tttgtttgat gcaggtctta
     1921 taagaaagat attaaagaat cctgtatata atgggaaaat agcatttgga agaagaactt
     1981 tagaaaaagt tcatggtaca agaaatgaat ataagcaggt tgaacaagat gaatatctaa
     2041 tatctgaagg gatacatgaa gctatagttt ccgatgaagt ttggcaagct gctcaggtta
     2101 agctaaaatc tcaagcaaag aaatatgagc atgtgaataa aggaaaagat acacgcacac
     2161 acttgctttc tggaattgta aaatgcccga tatgtggagt gggaatgttt gggaacaagt
     2221 gtatcaagaa aaagaaagat ggcacaaagt ataaagattt ttattacttt actatggttg
     2281 taaacatagg cagatgataa gaggtcataa gtgtacattc agtaagcaaa ttagagaaga
     2341 attgttagat gatgctgttg cagaggtgat tgtcaagata gtaagtaatc cgaaatttgc
     2401 ttctatgatg caagaaaaaa tcaacatgaa ggtggatacc tctgaaatag aaaaagaaat
     2461 agataattac caaaaggaat tgagaaagag tcattctaca aagtttaagc taattgagga
     2521 aatagataat ttagatgttg aagataagca ctataagaga aggaaacagg atttagatga
     2581 tagactatat cgtatgtatg acaaaataga tgaattagaa tcatcactaa ttgatgcgaa
     2641 agcaaagaaa cagactattg aagctgaaaa acttacagga gataacatat ataaggttct
     2701 gatctatttt gataagctct ataaagtcat gaatgatgta gagcgtaggc agttaatttc
     2761 agctttgatt tctgaaattc aagtttatga agaaaaacaa tctaacggac aatggctaaa
     2821 atccattact tttaagctac caattataga agaaaatctc aacatagatt tggacaatga
     2881 tgaacaagtt gaatgtgtaa gtttattaga gaaacgtagt taatcctcaa aaggttcccc
     2941 aaactttttg agtcccactg acgcatcacg ctgaggcggt atcactgctt gtacgagttg
     3001 aagcatcagc gaagtaaaag tagatgttca gccaatgcga cgaggtgaga ccgaaggtcg
     3061 ataaggtgtg ttctgggtat aggactcgta aagtaagtag gaaatatgat gagatgatac
     3121 agagagcctg aattggtcag gtgacgtgct tatttacatt agcctgataa tgaaaatgga
     3181 gagattatcg atggttatat tggaattgta ccaaaatgat tattctaaag atttagtagc
     3241 atttgattcc atagaagatg ggaaagcctt tgtggctcaa atcccgggat acactctgga
     3301 aacagaagat ggttttgaag tggagtattt taatcctaaa aacataccgg attatatgga
     3361 aattattttt aacggaaata ttgttccttt atctaaattt atgttcgatc ctgaggaaaa
     3421 tgtaaacatt atttggaaag agatttcaaa tttatccctc aaaaatgata gagtgatcga
     3481 aggatattca aaaattgatg catatgtcgt taacaaccat gaagttaaag cctatgtcga
     3541 aacaagagaa acgaactatc gtaaagcaaa agacttctta gaaagccgcg gatatgaaat
     3601 cgacagaagc tttttcggaa gtgaagacgg tgaagcgatt ctttacagaa aaaaagggat
     3661 cgaagtttgg catttcttgt gtcacttaga cccaatgttt gtagagattg aagatgtaga
     3721 aggatatgtt aaagaagaag ttggagagat tcaatagtca accaaagttc cttgtgagta
     3781 tatacctttg ctagtaaaag agtcaaaacg ttataacgaa gggggggaag aaaacccttg
     3841 agtgtaagtc tttttcttgt ttagagggaa agtattagag tagccgctca taatttatac
     3901 tagatttgat aactgatttg agacagattt tatttctata aatattgtga aaatttttta
     3961 ataccaaaga tttaaagtta ctgtgttaaa aatcctctcc acttttaaac taatgtatta
     4021 taaaagccag ttgacacaag tgttacacct gtgatagaat taacttgagg tgatgaaaat
     4081 ggcaaccgat aaaaatagaa taatgattag cttggatgat aaaaatctag agaaacttga
     4141 aaatttagta gaagatgcta gagatagaag gggaatgcga ctaacaaagt cccaggttat
     4201 tgaattactc ctaaataccg ttgattattt cgatgatatt atgggggcta tttactcaaa
     4261 aaaataagag caaaattgct attatttttt acaaattggt gtaacactag tgatatagga
     4321 gtgatgaaat ggttgtttat attagacaaa gtaaattacc aagtgaggtt tcaattaata
     4381 aatacaatgc tcaagtaggt gcctacttac aaggagaaga agctgtttta tatcaatctt
     4441 tttctgaaat aaaagagtta acaagtgaag atatagttgt agattatata atggagacta
     4501 gagcattact aaaaatgatg ggcttaaacg ttccggttca tgactatcct attgagctta
     4561 aagagtttta tggtcgaaag atttatgctg gtattttagg agagattgtg aatatacctg
     4621 ataattgggg aaaatttatt aagcctaaag ctggttcaaa agtctttact ggaagagttg
     4681 ttaatggaac ccatgattta ataggtattg gtctaccttt cgactatcct atatggatta
     4741 gtgaggttgt agaattcata gctgaatggc gttgttttgt gttagatggt cgcgtattag
     4801 atgttcgacc ctatacaggt gattatcatg cacaatttga tgcaagtgta attgatgaag
     4861 cgatatcatg ttggaaagat gcgccaatag cttatggact agatatcggt gttactcgcg
     4921 atggcagaac acttgttgtt gaagtaaatg atggttatgc attgggaaat tatggcctat
     4981 ctcctttaaa atcaatcaat tttcatagag ctaggtggaa agaaatggta aaaccctatt
     5041 ttgaaaaaaa tgaaattttt aaaatccaac aggatgttgt tttctaaaat aaatatggta
     5101 tataaccaat ataaaaagca tcaaaatgaa caaggaggaa tctgatgctt ggagcaatta
     5161 ttggagatat tgtcggttct gtttacgaat ggaacaatat caaaacaaag gactttcctt
     5221 tatttcggaa ggactgcttt tttacagatg acacggttat gacctgtgct gttgcagaag
     5281 caattatgaa tggtggacaa aaagacgact tcattgacgc gatgaagaaa tatggcagaa
     5341 tgtatccgaa tgctgattac ggtgctcggt ttaatgcatg gctaaacagc gataaccgtg
     5401 agccttataa tagctttggg aatggatcag ctatgcgtat ttctccatgt gcttggatca
     5461 tggactgtgg tttttatgcg aaaactggta tatggccatc atctagagga cttacgagtc
     5521 tttctgcaga ggtaactcat aatcatccag aaggtgtcaa aggcgctatg gctacagctg
     5581 atgctatctt tctatgtcgt ttttaatttg gtggttattg tagagagtac gagtaatcaa
     5641 ttaacgacaa tcctatagag tgtaaaagac gaattaagga ttatatagaa aaagaatacg
     5701 attacaatct atctcaaact ttagatgaaa tccgtcctaa ctatcgtttt aacgaaacat
     5761 gtcaggaaac tgtccctcaa gccattatcg cctttcttga aagtagagac ttcgaagatg
     5821 cgataagaaa tgccatctca cttggtggcg acagtgatac tctcgcagca atcacttgta
     5881 gcatagcaga ggcagcttac ggtattcctg attggatcaa ggataaggcc tattcttact
     5941 tggatgaacc cttaaaggat gtagttaggc gatgggaaaa tagaataaaa gtgtattaat
     6001 ctccagtacg tcagatttct cttttctgta ttttcattgt ataataggat tacatttact
     6061 tgcatacgac gaaatgtaaa catttctatt taaaattaag gataaaatca atgaaaaaag
     6121 caatggtaat tatcaaccct acttctggtg gcgagaaggc tttggattac aaagaaaagc
     6181 tggagaataa agcaaaagaa tactttgaat atgttgaaac caaaattacc gaaaaagcgc
     6241 tggatgcaac acattttgct gaagaagctt ctcgtgagca gtatgatgca gtggttgtgt
     6301 ttggtggaga tgggactgtc aatgaagtca tttcaggtat tgatgagaga gactacattc
     6361 ctaagttagg gattatccca ggcggtacgg gtaacctcat tacaaaactt ttggaaatca
     6421 atcaagacat cgatggcgca attgacgaac tggattttga tttaaccaat aagattgata
     6481 tcggtaaagc aaatgacaac tattttggtt atatctttag tatcggttct ctgcctgagg
     6541 cgattcacaa tgttgaaata gaggacaaaa caaaacaagg tattttagcc tatgctgtaa
     6601 atactatgaa gtctgtcatg acagatcagg tctttaacat taaggttgag acagaaaatg
     6661 gaaattatgt tggtgaagct agccatgttt tggtcctttt gacaaattac ttcgctgata
     6721 agaaaatctt tgaagaaaac aaggacggct atgccaacat tttgattctg aaagatgcct
     6781 ctatattctc caaattatcc gtcattcctg atttattaaa aggggatgtt atcgcaaatg
     6841 ataatatcga gtatatcaaa gcgcgtaata ttaaaatctc ttcagatagt gaattggagt
     6901 cagatgttga cggagataaa tcagataacc tacctgtaga aatcaaagtc ctagctcagc
     6961 gagtagaagt attttcaaaa ccgaaagagg attagtatat agagaaagcc ttttttaagg
     7021 ctttttgtat actttaaaag atagttcctt taacaacgga cattccttgc aaatagttca
     7081 caaaaatagt atactggatt cattgagttt gaaaacgttt gcgtaaaatt tgaatgaata
     7141 ctttaggaga taaattgatg gaattgagtg ctatttacca taggactgag tcggagtatg
     7201 cctatcttta taaggataag aaactccata ttcgaattcg aactaagaaa ggggacattg
     7261 aaagcatcaa cttgcactat ggggaccctt ttatctttat ggaggagttt tatcaggata
     7321 caaaagaaat ggtcaagata acttctggta ccttatttga ccattggcag gttgaagtgt
     7381 cagttgactt tgcacgtatc cagtatcttt ttgagctcag agatacagaa ggtcaaaata
     7441 ttttgtatgg cgataaaggg tgtgtggaaa attctctaga aaatcttcat gcaattggga
     7501 atggatttaa gttgccttat cttcatgaga ttgatgcctg caaggttcct gactgggttt
     7561 caaatacggt atggtatcag atatttcctg aaagatttgc caatggcaat gctctattaa
     7621 acccagaagg gactttagac tgggattcat ctgtcacacc taagagcgat gatttctttg
     7681 gtggtgattt acaggggatt attgatcata tggattactt gcaagacttg ggtattactg
     7741 gactatatct ttgtcccatc tttgaatcta caagcaatca caagtacaat acgacagatt
     7801 actttgaaat tgaccgtcat tttggagaca aggagacctt tcgggaactg gtggatcaag
     7861 cgcatcatcg tggcatgaaa gtcatgctgg atgcggtatt taatcatatt ggttcgcaat
     7921 ctcttcaatg gaaaaatgtc gtcaaaaatg gtgaacagtc tgcttataag gattggttcc
     7981 atattcaaca attcccagtg acaactgaaa agctagttaa taagagagac ttaccctatc
     8041 atgtttttgg tttcgaggac tatatgccta agctaaatac agccaatcca gaggtcaaga
     8101 attatctttt aaaggttgcg acttattgga ttgaagagtt taatatcgat gcttggcgtt
     8161 tggatgtggc taatgagatt gaccatcagt tctggaagga ttttcgtaag gcagttttag
     8221 ctaaaaatcc tgatctttat atcctaggag aagtctggca tacatctcag ccttggctaa
     8281 atggagatga gttccatgcc gtcatgaatt atcctttatc tgatagtatc aaggactatt
     8341 tcttacgagg aattaagaag acagaccagt tcatcgatga aatcaatgga gagtctatgt
     8401 attacaagca gcagatttca gaggtcatgt ttaatctctt ggattcacat gatacagagc
     8461 gaatcctgtg gacggccaat gaagatgttc aactggttaa atcagcctta gcctttctct
     8521 ttttacaaaa aggaacaccg tgcatttatt acggaaccga gctagccttg actggaggac
     8581 cagatccaga ttgtcgtcgt tgtatgcctt gggaacgtgt atcaagtgac aatgatatgc
     8641 tgaactttat gaagaggctg attaagattc ggaaatacgc gtcagtaatc atttcgcatg
     8701 gcaagtatag ccttcaagaa atcaaatctg atctagtagc tctggaatgg aaatacgaag
     8761 gacggatcct caaagcaata ttcaaccaat caacagaaga ttatctttta gagaaagaag
     8821 cagtagcact agcaagcaat tgccaagaat tggagaatca gcttgtcatc tctccagatg
     8881 gatttgtgat tttctaaaaa ctagttgatg aagattatgg tacatttcat atcttatata
     8941 gtataataag gctagttact aaacttgtaa aggagaactt aaatgaattg tagaggacat
     9001 gaaacaagac aaagaattgt tagagatttt gaagtttagc ctaaagcaca tattaagctg
     9061 ttagcaaatc aacaaaaaca tagtgatgca ggagcaacta ttgaagatga atattatgta
     9121 tttatcgctg agagtaaaat tgatggcaag aaggaagtta ttcagtgttg catgggtgcg
     9181 gcaagggatt ttttagaact aattaatcac aaagggctac ctctttttaa tccgcttgta
     9241 ggtgattctc atgtaaataa tagacaagaa tatgacaata cagggagtgg aaatttacaa
     9301 cctgaaaagt ggaatgaaac tgcaaagcag ctttataatg ttataatgtg gttgattatt
     9361 ttatggaatg ctaagccgga tacaccttta tttaatttta aagacgaagt aattaagtat
     9421 aaaacatatg agccttttga aagcagtata aaattggtat caatcaatga gtaacaaagt
     9481 atcagcatga ttcgaaacat ttacttgtaa tttgcggagg aacatcaata tggatggaat
     9541 aacaaaagat tttataaaaa cggctaaact aatgaaacaa ttatggcccc aattgaccga
     9601 taaagaagct attgatgaag taaaaaaata tacgaatggc aaaaatactg caatctttac
     9661 tgaagttgaa ggtgacacaa ttgtaggtct agcactatgt tcactcagat ttgattatgt
     9721 tgaaggttgt aaatatagtc ctgttggatt cttagaaggg attattgttg acgaggaata
     9781 tcgtttaaag gatattgcta aaaatctctg tacaaaatgt gaggaatggg cgaaaaataa
     9841 aggatgtaag gaatttgcaa gtgactgtac tttaacgaat acggattcta taagatttca
     9901 tctcaatatt ggatttcagg aggcaaatag aattattcat tttaagaaaa aattataatt
     9961 tagaaacgtg aataaacttg tttaaacttt atgtatcttt agaaagtgtg ttaacttgaa
    10021 agaacaaatt tttttgatgg gtgggaatcc cccaatgaag aaatatagta tt
//
